LOCUS       DAZULR010000001       109245 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.001, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000001 DAZULR010000000
VERSION     DAZULR010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 109245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 109245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..109245
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.001"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            59..667
                     /locus_tag="ACG8ZV_000001"
     CDS             59..667
                     /locus_tag="ACG8ZV_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFS4995378.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            835..2472
                     /locus_tag="ACG8ZV_000002"
     CDS             835..2472
                     /locus_tag="ACG8ZV_000002"
                     /EC_number="4.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004612 - phosphoenolpyruvate
                     carboxykinase (ATP) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HFS4995379.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(2544..3656)
                     /locus_tag="ACG8ZV_000003"
     CDS             complement(2544..3656)
                     /locus_tag="ACG8ZV_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFS4995380.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(3731..5104)
                     /locus_tag="ACG8ZV_000004"
     CDS             complement(3731..5104)
                     /locus_tag="ACG8ZV_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4995381.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            5325..5942
                     /locus_tag="ACG8ZV_000005"
     CDS             5325..5942
                     /locus_tag="ACG8ZV_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFS4995382.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            6040..6495
                     /gene="argR"
                     /locus_tag="ACG8ZV_000006"
     CDS             6040..6495
                     /gene="argR"
                     /locus_tag="ACG8ZV_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFS4995383.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            6513..8015
                     /locus_tag="ACG8ZV_000007"
     CDS             6513..8015
                     /locus_tag="ACG8ZV_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HFS4995384.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            8110..8316
                     /locus_tag="ACG8ZV_000008"
     CDS             8110..8316
                     /locus_tag="ACG8ZV_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995385.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            8402..8803
                     /locus_tag="ACG8ZV_000009"
     CDS             8402..8803
                     /locus_tag="ACG8ZV_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HFS4995386.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            8958..10289
                     /locus_tag="ACG8ZV_000010"
     CDS             8958..10289
                     /locus_tag="ACG8ZV_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HFS4995387.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            10311..10937
                     /locus_tag="ACG8ZV_000011"
     CDS             10311..10937
                     /locus_tag="ACG8ZV_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HFS4995388.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            11120..11701
                     /locus_tag="ACG8ZV_000012"
     CDS             11120..11701
                     /locus_tag="ACG8ZV_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFS4995389.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            12433..12995
                     /locus_tag="ACG8ZV_000013"
                     /pseudo
     CDS             12433..12995
                     /locus_tag="ACG8ZV_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349929.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase"
     gene            complement(13200..13538)
                     /locus_tag="ACG8ZV_000014"
     CDS             complement(13200..13538)
                     /locus_tag="ACG8ZV_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995390.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            13825..14055
                     /locus_tag="ACG8ZV_000015"
     CDS             13825..14055
                     /locus_tag="ACG8ZV_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFS4995391.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            14055..14396
                     /locus_tag="ACG8ZV_000016"
     CDS             14055..14396
                     /locus_tag="ACG8ZV_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFS4995392.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            15246..15431
                     /locus_tag="ACG8ZV_000017"
     CDS             15246..15431
                     /locus_tag="ACG8ZV_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995393.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            15936..16130
                     /locus_tag="ACG8ZV_000018"
     CDS             15936..16130
                     /locus_tag="ACG8ZV_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995394.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            16321..16570
                     /locus_tag="ACG8ZV_000019"
                     /pseudo
     CDS             16321..16570
                     /locus_tag="ACG8ZV_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(16814..17644)
                     /locus_tag="ACG8ZV_000020"
     CDS             complement(16814..17644)
                     /locus_tag="ACG8ZV_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HFS4995395.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            17852..19186
                     /locus_tag="ACG8ZV_000021"
     CDS             17852..19186
                     /locus_tag="ACG8ZV_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFS4995396.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            19227..20138
                     /locus_tag="ACG8ZV_000022"
     CDS             19227..20138
                     /locus_tag="ACG8ZV_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4995397.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            20135..20989
                     /locus_tag="ACG8ZV_000023"
     CDS             20135..20989
                     /locus_tag="ACG8ZV_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4995398.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            20986..21603
                     /locus_tag="ACG8ZV_000024"
     CDS             20986..21603
                     /locus_tag="ACG8ZV_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HFS4995399.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            21605..22123
                     /locus_tag="ACG8ZV_000025"
     CDS             21605..22123
                     /locus_tag="ACG8ZV_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HFS4995400.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            22420..22878
                     /locus_tag="ACG8ZV_000026"
     CDS             22420..22878
                     /locus_tag="ACG8ZV_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFS4995401.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            22987..26928
                     /locus_tag="ACG8ZV_000027"
     CDS             22987..26928
                     /locus_tag="ACG8ZV_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFS4995402.1"
                     /translation="MEKLDEPIVPSGQALQRIQRQLFNGILERLGPTATQDPYEYIYP
                     SGEVENEQHRYPKFTTNDYTKVLGNWTQSNERYQGDKGSPYDGENLIDDSDYTNGGAN
                     WRNYDYATNNGSTAGEEDRNVPAQTVQLWGNERNFENSYLDYNGAYIKKWVEPVLPSS
                     TASDLHPEDATTLYNVYLDVIGGEKKEISPIDIVFVLDKSASMSELTAGTNSQTKNAA
                     LIEAVNEMSKDLLSDPSLDIRIGMVNFYHNSTAINNHEQISSDIFPLTNDINRLTGSE
                     NTALNRTPIGGTPLTLGLKNGYETLYKDNGGENRNPEKILIVVGDGTPTFSYAPIQSS
                     YRTSTNGAWSNWTVMEDKIAEDNDVLFRNFEEFSGNTSNAGFTHPVTYASDFNRPEDE
                     VNVHYRYGEVKEGDNKATHWVGDGSSNNNTNGSPTSQEKSSAINTVAYHHWLKNKYQE
                     NPPSIFSIGLGIDGNVSGRQRLDAIGRNVLKNIADLEEDGVTPRYYNANNKNDIVTAL
                     EDISSTFKRTIQQATLYDETGFNVSPFGAGRSADIQFYHLDPGENGMKYQEPEIWDEE
                     RHGQAPPEVVATPTTYVGRENQAYKFSPISLGEGEMVRIKYQVKLDAGAQDGNFCTVN
                     NMAYIQNLEDYENDITTGRMYFPSSSIRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQ
                     NPESGEAEPIETSKTTTDGIAIFETKMPILGDETGAVSDIFWIREIAGPPRYQLVDET
                     YQFQIKKYAANEDEMLGHYELVDEYTSGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNI
                     EGTEYDELYVKLEMRNEFKPIHMNINKLIEGSNMPINGAEFELYETDGNGLEIGYPVA
                     KGLSGVNEVEEEKGRLTFYSVDEDGKYVIVDGEKVIHPIGEPDSFVYKDSEETTNYAE
                     YKIIESQNPEGFKEPDENDTWILRLYDNAIGTIQLKQTGEENWQYLTYTTDEEDRLWV
                     AFTAYNTFDYREIRVRKLDHEGHTLDGAGFDIRKVGDSSFPLYRAYTGNPLEPEESKR
                     LPGIGYFYSRAVGVEKYVDLNYDQPLHLSIGEYEVSESVAPNGYRLSDQVFQFALNEE
                     GKFIIEDTVIEDETAPLPEGYEIIDGVLQVTLEDELAPIDLELLKIDSMNSRRLEGAE
                     FSIEKQNSAGEYEIIEGGLAPDPNDSSLFNASDLLEGVYRIKEVKSPDSYRKLPGYFI
                     LEISYREEPDIENDRVVPGKEAGTLKVEISYYPNEEAETPDLQQELEYELLETNRIRL
                     QLSVGNDPENPLPATGGSGRLFYILLAAFFMALAGAAYGLFVRQSKKEGAR"
     gene            26928..28241
                     /locus_tag="ACG8ZV_000028"
     CDS             26928..28241
                     /locus_tag="ACG8ZV_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
                     /protein_id="HFS4995403.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            28234..29931
                     /locus_tag="ACG8ZV_000029"
     CDS             28234..29931
                     /locus_tag="ACG8ZV_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFS4995404.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            30005..30898
                     /locus_tag="ACG8ZV_000030"
     CDS             30005..30898
                     /locus_tag="ACG8ZV_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFS4995405.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            31082..31756
                     /locus_tag="ACG8ZV_000031"
     CDS             31082..31756
                     /locus_tag="ACG8ZV_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFS4995406.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            31774..32799
                     /locus_tag="ACG8ZV_000032"
     CDS             31774..32799
                     /locus_tag="ACG8ZV_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFS4995407.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            32888..33754
                     /locus_tag="ACG8ZV_000033"
     CDS             32888..33754
                     /locus_tag="ACG8ZV_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HFS4995408.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            33791..35167
                     /locus_tag="ACG8ZV_000034"
     CDS             33791..35167
                     /locus_tag="ACG8ZV_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFS4995409.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVIILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(35268..36464)
                     /locus_tag="ACG8ZV_000035"
     CDS             complement(35268..36464)
                     /locus_tag="ACG8ZV_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HFS4995410.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(36588..37250)
                     /locus_tag="ACG8ZV_000036"
     CDS             complement(36588..37250)
                     /locus_tag="ACG8ZV_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HFS4995411.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            37478..38041
                     /locus_tag="ACG8ZV_000037"
     CDS             37478..38041
                     /locus_tag="ACG8ZV_000037"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFS4995412.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            38054..38338
                     /gene="macP"
                     /locus_tag="ACG8ZV_000038"
     CDS             38054..38338
                     /gene="macP"
                     /locus_tag="ACG8ZV_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall synthase accessory phosphoprotein
                     MacP"
                     /protein_id="HFS4995413.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            38357..39049
                     /locus_tag="ACG8ZV_000039"
     CDS             38357..39049
                     /locus_tag="ACG8ZV_000039"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HFS4995414.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            39061..39606
                     /locus_tag="ACG8ZV_000040"
     CDS             39061..39606
                     /locus_tag="ACG8ZV_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HFS4995415.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            39877..43167
                     /locus_tag="ACG8ZV_000041"
     CDS             39877..43167
                     /locus_tag="ACG8ZV_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFS4995416.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEVPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGPDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKDHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERLTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNQATGEVLENAKDLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     ASYETKEILHTVDYRKPNYSTVYVTPEGSDTGNGSRQNPLSLTQALRYAYAGQTIVLA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWVLR
                     GFDVTNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVVIK
                     NSVAYRNGWVPGVEGEGNGNGFKMGDSSLSGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDFHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTVSKDWIESLNTHSQEGQQPVTRYANGSIHVHGLMQIKPEN
                     RQTEKGRVDGLPLSVGATFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVV
                     YVMKQRKK"
     gene            complement(43585..45492)
                     /locus_tag="ACG8ZV_000042"
     CDS             complement(43585..45492)
                     /locus_tag="ACG8ZV_000042"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M13-type metalloendopeptidase"
                     /protein_id="HFS4995417.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNEQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIQYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            45622..46497
                     /locus_tag="ACG8ZV_000043"
     CDS             45622..46497
                     /locus_tag="ACG8ZV_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HFS4995418.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            46577..47551
                     /locus_tag="ACG8ZV_000044"
     CDS             46577..47551
                     /locus_tag="ACG8ZV_000044"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HFS4995419.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            47730..48875
                     /locus_tag="ACG8ZV_000045"
     CDS             47730..48875
                     /locus_tag="ACG8ZV_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HFS4995420.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSSEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            49012..49356
                     /locus_tag="ACG8ZV_000046"
     CDS             49012..49356
                     /locus_tag="ACG8ZV_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HFS4995421.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            49627..50913
                     /gene="efmA"
                     /locus_tag="ACG8ZV_000047"
     CDS             49627..50913
                     /gene="efmA"
                     /locus_tag="ACG8ZV_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HFS4995422.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(51051..51650)
                     /locus_tag="ACG8ZV_000048"
     CDS             complement(51051..51650)
                     /locus_tag="ACG8ZV_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFS4995423.1"
                     /translation="MNYFTSDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELITQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            52054..53175
                     /gene="mnmA"
                     /locus_tag="ACG8ZV_000049"
     CDS             52054..53175
                     /gene="mnmA"
                     /locus_tag="ACG8ZV_000049"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HFS4995424.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGDMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            53421..54842
                     /gene="arcD"
                     /locus_tag="ACG8ZV_000050"
     CDS             53421..54842
                     /gene="arcD"
                     /locus_tag="ACG8ZV_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0043858 - arginine:ornithine antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006527 - arginine catabolic process
                     [Evidence IEA];
                     GO_process: GO:1903826 - L-arginine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HFS4995425.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            54856..55974
                     /locus_tag="ACG8ZV_000051"
     CDS             54856..55974
                     /locus_tag="ACG8ZV_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HFS4995426.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SEFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVNPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILER
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(56034..57326)
                     /locus_tag="ACG8ZV_000052"
     CDS             complement(56034..57326)
                     /locus_tag="ACG8ZV_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HFS4995427.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMSFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSISSGHSPSHRQ"
     gene            57476..58036
                     /locus_tag="ACG8ZV_000053"
     CDS             57476..58036
                     /locus_tag="ACG8ZV_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFS4995428.1"
                     /translation="MKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDIKAPSLY
                     NHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSNQAVYEL
                     LISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYLSLRFLG
                     YFTKEPTIDPEDSYFWMINDFIATLP"
     gene            58165..58542
                     /locus_tag="ACG8ZV_000054"
     CDS             58165..58542
                     /locus_tag="ACG8ZV_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HFS4995429.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEAEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESGKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            58475..60547
                     /locus_tag="ACG8ZV_000055"
     CDS             58475..60547
                     /locus_tag="ACG8ZV_000055"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_function: GO:0098847 - sequence-specific single
                     stranded DNA binding [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0051304 - chromosome separation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFS4995430.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLNLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEEQKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERIPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKMLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(60758..61705)
                     /locus_tag="ACG8ZV_000056"
     CDS             complement(60758..61705)
                     /locus_tag="ACG8ZV_000056"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFS4995431.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            61951..62415
                     /locus_tag="ACG8ZV_000057"
     CDS             61951..62415
                     /locus_tag="ACG8ZV_000057"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HFS4995432.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQQILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            complement(62477..63520)
                     /locus_tag="ACG8ZV_000058"
     CDS             complement(62477..63520)
                     /locus_tag="ACG8ZV_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HFS4995433.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGIKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLFYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(64020..64985)
                     /locus_tag="ACG8ZV_000059"
     CDS             complement(64020..64985)
                     /locus_tag="ACG8ZV_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HFS4995434.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            65219..66064
                     /locus_tag="ACG8ZV_000060"
     CDS             65219..66064
                     /locus_tag="ACG8ZV_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFS4995435.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEIANSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            66255..67442
                     /locus_tag="ACG8ZV_000061"
     CDS             66255..67442
                     /locus_tag="ACG8ZV_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFS4995436.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            67448..67804
                     /locus_tag="ACG8ZV_000062"
     CDS             67448..67804
                     /locus_tag="ACG8ZV_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HFS4995437.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            67806..68144
                     /locus_tag="ACG8ZV_000063"
     CDS             67806..68144
                     /locus_tag="ACG8ZV_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HFS4995438.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     misc_binding    68220..68476
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            68539..69573
                     /locus_tag="ACG8ZV_000064"
     CDS             68539..69573
                     /locus_tag="ACG8ZV_000064"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HFS4995439.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            69566..70252
                     /locus_tag="ACG8ZV_000065"
     CDS             69566..70252
                     /locus_tag="ACG8ZV_000065"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HFS4995440.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            70276..71124
                     /locus_tag="ACG8ZV_000066"
     CDS             70276..71124
                     /locus_tag="ACG8ZV_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFS4995441.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            71321..72094
                     /gene="sufC"
                     /locus_tag="ACG8ZV_000067"
     CDS             71321..72094
                     /gene="sufC"
                     /locus_tag="ACG8ZV_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HFS4995442.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLVKRLEAEGYAGISKELGIDYKEEEA"
     gene            72107..73393
                     /gene="sufD"
                     /locus_tag="ACG8ZV_000068"
     CDS             72107..73393
                     /gene="sufD"
                     /locus_tag="ACG8ZV_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HFS4995443.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            73390..74625
                     /locus_tag="ACG8ZV_000069"
     CDS             73390..74625
                     /locus_tag="ACG8ZV_000069"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HFS4995444.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAH
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     SFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVINPVQELAELVHENGGVIVVDGAQSAPHMTIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQELGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VIAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFKHGTI"
     gene            74612..75082
                     /gene="sufU"
                     /locus_tag="ACG8ZV_000070"
     CDS             74612..75082
                     /gene="sufU"
                     /locus_tag="ACG8ZV_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="HFS4995445.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            75087..76478
                     /gene="sufB"
                     /locus_tag="ACG8ZV_000071"
     CDS             75087..76478
                     /gene="sufB"
                     /locus_tag="ACG8ZV_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HFS4995446.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(76573..77715)
                     /locus_tag="ACG8ZV_000072"
     CDS             complement(76573..77715)
                     /locus_tag="ACG8ZV_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4995447.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(77754..78488)
                     /locus_tag="ACG8ZV_000073"
     CDS             complement(77754..78488)
                     /locus_tag="ACG8ZV_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFS4995448.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIIEEFDNNILLLTSSIEEQLEEMIDEGIHSQVEDMNYPEEAVNEIIDN
                     INKLKQTISSIGKKYTKKKMKGGDTI"
     gene            78723..78998
                     /locus_tag="ACG8ZV_000074"
     CDS             78723..78998
                     /locus_tag="ACG8ZV_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4995449.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMEQYKG"
     gene            79096..81093
                     /locus_tag="ACG8ZV_000075"
     CDS             79096..81093
                     /locus_tag="ACG8ZV_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995450.1"
                     /translation="METSMINIPIYVDQEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSVEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLEKIHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVGDNSVKNALIKNRGYFVKQGFTLERASKDIKKLYNVKASSSFLIYLAKGAGI
                     DETIKELILSGAGIVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(81169..81504)
                     /locus_tag="ACG8ZV_000076"
     CDS             complement(81169..81504)
                     /locus_tag="ACG8ZV_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFS4995451.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            81631..81846
                     /locus_tag="ACG8ZV_000077"
     CDS             81631..81846
                     /locus_tag="ACG8ZV_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFS4995452.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPINELFSDVFNKVNS"
     gene            81883..82245
                     /locus_tag="ACG8ZV_000078"
     CDS             81883..82245
                     /locus_tag="ACG8ZV_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HFS4995453.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGADEVKKSTEQTFS
                     EMKEQIVHGQETGKLYLIIGWVSMVVSLAFIPVVFGAVAVIMGYLYRETDEKMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            82291..82617
                     /locus_tag="ACG8ZV_000079"
     CDS             82291..82617
                     /locus_tag="ACG8ZV_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995454.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKATLDNGSAININVEYYPKKDRVYVEIPYT
                     EVLMLN"
     gene            82818..83594
                     /locus_tag="ACG8ZV_000080"
     CDS             82818..83594
                     /locus_tag="ACG8ZV_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995455.1"
                     /translation="MMKKNYLKTGIFLVIGTILVIQLSGCRNKDKDFYGYWSGTAEKI
                     PVDYNFKITKDRVIELQKNGEMVDFKYTLRHKKFDSTTFRSIMISKDELVKAIPELKE
                     TTGISNITFMPIDGEKDKLTVLVNLDEHLSTATLYRTTKDESPIGKVEKKNDTISRQT
                     VDKKIDTFIKTYAAIPPTWKLVNEDKGITINTDTEIPTDAQSLSDLLANLTGVSNAVS
                     EQVGKDIPLRLLENGKKDYSVVFKNGKVTDYNEIFEKVIE"
     gene            85350..86135
                     /locus_tag="ACG8ZV_000081"
     CDS             85350..86135
                     /locus_tag="ACG8ZV_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006701865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylase"
                     /protein_id="HFS4995456.1"
                     /translation="MVEDMVMVEEEQGRLIKSKKRVQKHGEVFTPQRTVKDMLDLPGI
                     KEACEELQTTFLEPSAGEGAFLVEVLTRKMAMVAREYNESLEQYENYSLLALSTLYGV
                     ELLEDNAQTCVMNMFQVFNDLYREQSKKHGTAMKRKVQDSAKTLISRNIKQGDFLTKR
                     TPDDNPIIFSEWTPKTLRKGQKKITVNRTEYSLEDIYSGVTREFGEAYSALPVFEQLD
                     LFSFDDEVDEEVSNDPILRYVAMPITEVYKEEMEEIDDDSVEI"
     gene            86113..90510
                     /locus_tag="ACG8ZV_000082"
     CDS             86113..90510
                     /locus_tag="ACG8ZV_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019788126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Eco57I restriction-modification methylase
                     domain-containing protein"
                     /protein_id="HFS4995457.1"
                     /translation="MTTALKSKAKYFDYLPKYGSKLEHFLGIPNLVDAINTYRVTVNQ
                     IPNEVAIGTRRYSEVAARKIASNVGIDQQSMKYVDVLRELRVRNNITPTIADLFHKLR
                     KYGNVAAHENGIIPVSEAVESLVTLDTLLRVFARNLSGDKSLNPKEEITDEMFVITYN
                     TFDRKLIYIQSAKDADGTWKMYQGLEKIGDASVPENYEADFTPNSEYLREYASRRIKQ
                     YMTTAGVPFVLHWAQLAVNKKNQFFRDHDVHEVLKRSGYNPQTIGEDDTGKPNEWFSV
                     TVDVAKKAIQAVKDGKGSLDSEKDDFDEFKINFRPEQKDAIEQTKTVFKTKDEMLWNA
                     KMRFGKTLSSLQVIKESQYKKVLIMTHRPVVSDGWFTDFKKIFTDGSYIYGSKQDGEK
                     IQNLVDTEKPFIYFASIQDLRGSEWAGGKAGDKNYEFLAIDWDFIIIDEAHEGNETEL
                     ANNVKAKLRKEHTKVLELSGTPFNLFDKYDEDNIFTWDYTMEQEAKEKWSVEHPNEPN
                     PYEGLPKVSMFTFEIPNKFDYFDENKAFNFREFFRVKEDDETKLLHEGDVRKFLDYIT
                     TNDEKTNFPFSKPEFRENLRHTLWLMPGVKEANAFERVLETHPIFKDYNIANVVKTGD
                     SEHASDSDLELVRKAIGNPAKSKTITLTVRKLTTGVNVPEWTGVFFLSNTESPTSYLQ
                     AAFRAQTPFNHAELGIKKNCYIFDFAPDRALKIMSGSVGLTSKKGKVNSSEQKKKLER
                     MLNFLPILGKQGNVMKEFSVDRMLTALKKAYAEKAVRTGFEDSSLYNDNLLNLDQADL
                     TKFEDLKKIVGSSKPTKVKDFIVSDNGMSEEEYEKASRAEKKPKRQRTKEEQEAIDRA
                     KRLREQRNKMISILRGVSIRIPMMIYGMDIDIKDDVTIEMFLNLVDEASWNEFMPEGL
                     SKGRFREFIEYYDADVFVEAGRIIRRRAKSYDELDVIERTRKIGELFSTFKNPDKETV
                     LTPWRVVNMHLGNTIGGLSFFDEEYQNSTENGQPIVRWRKTDCTDDIFKENRKILEIN
                     SKTGLYPLYAATSMYYVQLLKQSDINAGRVDSEAIWEKVLSEQIFVISKTPMAKTITK
                     RTLIGYNAWKVNVEYSSELVTSMKRSINDGLTNLKGVYKNVKFDVIIGNPPYQEKDGG
                     SGASATPLYNLFVETSVKLSERYVSMITPSKWFAGGKGLDKYRDFMLNSSSLKVMVDI
                     VNGKEIFPNTSIGGGVSYFLWDKKYNGLTQYTNQHDGVSNTQERKMNEFPVFVRYNEA
                     ISAIHKIGEHASVGDFVISRNPFGLPTKIRGEEVQDSRNSIKVISSGGVGFVPLEDIT
                     KGQDMVGKYKVISSSLTSEHAGEPNKNGMFKVISTNRVIKPNEVVTDSYLVLFSADTE
                     TEAINYLKYLRTRFYRFLLLQAVTSIHLSKDKFMFIPVQDFTSGSDINWNVGIEEVDM
                     QLFKKYSFDASEILFIDQTIVPILHEEYY"
     gene            complement(91950..92615)
                     /locus_tag="ACG8ZV_000083"
     CDS             complement(91950..92615)
                     /locus_tag="ACG8ZV_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4995458.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDF
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            92741..94777
                     /locus_tag="ACG8ZV_000084"
     CDS             92741..94777
                     /locus_tag="ACG8ZV_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HFS4995459.1"
                     /translation="MIIKKKFTVLLTIIVTGIMSGFALVSINKQVLYRTNEFFHQTDT
                     YTPIRLPQHFIGQEEYEQLIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLE
                     MTLYYQGDVKSSHEKVPYSNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERVISLF
                     TDRFNQAFHTDYATNIFEDFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLL
                     MNKEISLLLNNDFSLHQVLWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYV
                     FLFSGIYGISLISLLLVEKIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFS
                     SSQLAVSHEPPKEIAGEDYHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSI
                     LVNVSDYLNEENEQFGRGIKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRH
                     TDLKNDLAQITEYYQEISEKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSM
                     YLERNILSGEIYPPLKIKIGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLS
                     RSFHYLIQIFLLTFFSFFLLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNL
                     IKWGTTSVIFLFLIEREPKYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            94781..95419
                     /locus_tag="ACG8ZV_000085"
     CDS             94781..95419
                     /locus_tag="ACG8ZV_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4995460.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            95447..95875
                     /locus_tag="ACG8ZV_000086"
     CDS             95447..95875
                     /locus_tag="ACG8ZV_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995461.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            96332..97243
                     /locus_tag="ACG8ZV_000087"
     CDS             96332..97243
                     /locus_tag="ACG8ZV_000087"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFS4995462.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            97460..97897
                     /locus_tag="ACG8ZV_000088"
     CDS             97460..97897
                     /locus_tag="ACG8ZV_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995463.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            97992..98876
                     /locus_tag="ACG8ZV_000089"
     CDS             97992..98876
                     /locus_tag="ACG8ZV_000089"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFS4995464.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            99100..102267
                     /locus_tag="ACG8ZV_000090"
     CDS             99100..102267
                     /locus_tag="ACG8ZV_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HFS4995465.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSKYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            102335..102832
                     /locus_tag="ACG8ZV_000091"
     CDS             102335..102832
                     /locus_tag="ACG8ZV_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HFS4995466.1"
                     /translation="MILLLGFILWQTPVHASEFNFAVDFELPANQIDKNKTYINVRME
                     PGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESKSKFDETLSYDMKNLAK
                     TVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKENVSNKSTVGVVNQFSQV
                     KAILI"
     gene            102851..103315
                     /locus_tag="ACG8ZV_000092"
                     /pseudo
     CDS             102851..103315
                     /locus_tag="ACG8ZV_000092"
                     /inference="COORDINATES: protein motif:HMM:NF023225.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
     gene            103312..104070
                     /locus_tag="ACG8ZV_000093"
     CDS             103312..104070
                     /locus_tag="ACG8ZV_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFS4995467.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(104156..104896)
                     /locus_tag="ACG8ZV_000094"
     CDS             complement(104156..104896)
                     /locus_tag="ACG8ZV_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFS4995468.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            104957..106210
                     /locus_tag="ACG8ZV_000095"
     CDS             104957..106210
                     /locus_tag="ACG8ZV_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFS4995469.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLIGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            106532..106759
                     /locus_tag="ACG8ZV_000096"
     CDS             106532..106759
                     /locus_tag="ACG8ZV_000096"
                     /inference="COORDINATES: protein motif:HMM:NF013777.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFS4995470.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            106882..107208
                     /locus_tag="ACG8ZV_000097"
     CDS             106882..107208
                     /locus_tag="ACG8ZV_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HFS4995471.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            107276..107989
                     /locus_tag="ACG8ZV_000098"
     CDS             107276..107989
                     /locus_tag="ACG8ZV_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HFS4995472.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            108299..109150
                     /gene="licT"
                     /locus_tag="ACG8ZV_000099"
     CDS             108299..109150
                     /gene="licT"
                     /locus_tag="ACG8ZV_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HFS4995473.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
BASE COUNT        36174 a        18767 c        22879 g        31425 t
ORIGIN      
        1 aaatgataaa gttaatagcg tcgaaagaat aaaaaacgga gaaaaaaagg agtttaatat
       61 gaattcattt aagaaaattg ttttaggtac aacttttgct gctggtgcta ctgcaatgtt
      121 tgtaggaact acaaatgctc acgctgatga agtttataca gtaaaatcag gtgattcatt
      181 atctaagatc tcacaaaaat ttgcaggaga caactcaatg atcgatgcaa ttgctgaaaa
      241 aaattcgatc gcaaacatca accgcattta tgttggtgaa caattaacaa tcccaacttc
      301 aaatgattct tcagcaacaa cagaaaacaa aacaacagaa aatacagcat ctacaactga
      361 aacagcaacg caagaacata catacgttgc acctgttgaa acagttgaag tagctcctgc
      421 tgccccagct gctgcaacag cgccaacttc aagctctgca aaagaatgga tcgcacaaaa
      481 agaatcaggc ggttcataca cagctactaa cggacgttac atcggccgtt atcaattaga
      541 tgcttcatac ttaaacggcg actattcagc tgccaatcaa gaacgtgtag cagaacaata
      601 tgtaacatct cgttatggtt catgggatgc tgctaaaaca ttctggttag caaacggctg
      661 gtactaagcc gataaaagga aaatgatgaa accgagaaac ttgtttattc aagttctcgg
      721 tttttttgtg tgaaaaataa ctcgtttgct tcccacagcg cagcagtaca aataaaaact
      781 cgaataatgt ataataaaga aaacgttttt ttgtttaggg aatgaggagg agccatgagt
      841 acaaaagaga gtctcgaatt aaacgaaatc acaagtggaa atccactgtt atccagtatt
      901 cgatcgattg tagaaacgac attttacggt aataatgttc atgaagtttt tgataggaag
      961 acagcttatc aactagcaaa agggagtcca ggaacgatca tcacagattt aacaatctca
     1021 catgctgaag aactagattt accagctgat gttaggacac tagtattcaa tgatggaagc
     1081 attgtgggaa gaacagcaag tgctcggcgg atctttgagg acttagacaa ggaacaaagc
     1141 aaatacgaga aaattttaag agaagctgtg tatcaaagtc gcaagcgcca gttttaccat
     1201 acaaaagtaa tcgttggcct atctgaagaa ttttctgtgc aaagtcattt gctgattcca
     1261 gaaggatttg agaacaattt gtattcttat ttgctgaatt ttcagccagc gaattcgaag
     1321 atcttagaga cttatcaaaa gtctgtttcc tttgatgagg gagatcttta tatcttttgt
     1381 gatcccgaat ggacacatga aacatttcca aatggactca ttttgtttga tgctctccat
     1441 aatacagcgg ctgtgctagg attacgttac tttggagaat taaaaaaagc gactttgacg
     1501 cttgcttggg cattgggaaa tcgcaatggc tttattgcct gccacggtgg gatgaaacaa
     1561 tatgctagta atgaccagac ctatacgatg gctgtatttg ggttgtccgg ttctggaaaa
     1621 tcaacgatta ccttagcaaa acatacggaa ggtcactctg tttcgatctt gcatgacgat
     1681 gctttcgtta tttctcgaaa aaatggtttt gctactgcct tggaaccttc ttactttgat
     1741 aaaacacaag actatccgtc tgatgatccg gccatttctt ctttccttac ttgtcagaat
     1801 gtgggcgtga catgtacaag taaaggagaa aaagtcctag taacaggaga tatacgaaac
     1861 ggaaatgggc ggacagtcaa atcacgttat gcgacacccg accgagtcga tcatcttagc
     1921 gaaaagatcg atgctgtttt ttggatcatg aaagatgatt cgcttccgcc aattatcaag
     1981 atcaatgacc cagttttagc agcgtctttt ggtgcaacat tagcaacaaa acgatcagac
     2041 gcggaaaata tcactacaaa aagacagcta gatgagctag tcattgaacc atttgctaat
     2101 cctttccgtg tctatcctct tagggaagac tatcaagctt ttcgagagtt gtttttgaaa
     2161 cagcaaacag cctgctatgt cctgaatact ggatatttcg atgataaaaa aatcaaacct
     2221 gaaacgacat tgtcaatcgt tgaaagaatc gtgcaacaaa cggcagaatt caagtcgttt
     2281 ggtccatttg aagacatcca ctatttacct ataccagatt ttcctgtttc ttttgaggat
     2341 acgtcctata aaaatctggt gaaacaacga cttgatattc gtttacgatt cattgaagct
     2401 cagataggaa aagatctctt gccagatgaa gcaaaagaaa gtttggagaa tttgattcag
     2461 aaattgaact aaaataacag ctttttcaag aagtaatcca tgcgcaatat cgctcgggat
     2521 ccttacttga aaaagctgtt tttctatgat ggatttttcg taatataggt ggagatgtcc
     2581 ttttgataat cttccgtagg ccaatgacca gtatttaaga agttggctaa tagatagccg
     2641 atataaggac ctgtggtcaa gccagaagag cctagaccgc tagcagccag taagcttgga
     2701 tcatctggca gtacgccgaa aaatggggaa aaatctgacg tataagcacg ggtacctaca
     2761 cggaactcgt atggccagtt ttttatctga tctggatcag tcaagaactg ttctgtactc
     2821 ttagtcaatc ccttataagc ttcgctagta ggagccaaat cccagccttg atcgttttca
     2881 tgggtagcac ctaaaaggat ctttccatcc atgaaaggaa tgaaatcagc ttctccgtca
     2941 agcatagcaa caggccagtc ttgactcatc ttataagatg tctgaaatgc taagagctgc
     3001 cctttttgcg gacgtatatc tgcagcatag cctaattctt gtaataaagg cttaagtgcc
     3061 gggccaggtg tcaaaattac acgatcagct gtgtattctc caaacggtcc cttgatgagc
     3121 caagaatcgc tcttcttatg caaagtgact tttgcctgga tctgctccat ttgtttttgt
     3181 gctaaacgct gaccaagatg ttctaaatat gcttttccat ccagacgacc accaccactg
     3241 atacgcagtg aaactgctgg tttcaataac ggaagtgctt gagatgtctg ttcaggtgaa
     3301 agccattcga tgtttccaat ttctggcgct tcttcttttc gtttctcggc aagaacagcc
     3361 aattcagcta aatctttttc aggtcgaagc aaaagtgtcc ctgattgtgc gtaaatcgtt
     3421 tgatcaagtt ggaaatcttt tataagttta gggaaaaaag cagcgccgtc tttagccaga
     3481 cgataccatt gtttgtttct gcgtttcgac aaccaagggg agataatccc agcgctagct
     3541 ttagttgcct gtcctgtccc ttcatcaaat aaagcaacat tgaattttga tgtatctaag
     3601 taactggcta gggtcatacc aatgatcccg ccaccgataa tggcaatttt ttccataaaa
     3661 aagcctcctt ttacaaacaa ccattttcac acaaaaaaac ggcagatgca acacctgccg
     3721 tatatggaat ctacgctttt ttagcaaaga acagataata ggcgaatcga gcaaagctta
     3781 cgagaagcaa cagcaacaag acgcctaatg ctgcttttga tcctaatgta gtagacactt
     3841 catagttatg ggaagtatga tgctggacgt aattgataat gaccgctact aatgaagtag
     3901 ccacagcgcc agaaaactgc tgcaaggtat tgaacattgc gttcccgtct ccttgtagtt
     3961 cttcattcag tgcattcatt ccggtggtca tcatattgct gtaagataat ccgataccga
     4021 tcatataaaa cacatgacaa gcaatcaata cacccactga agcgtgtcct atgagtagga
     4081 ataatgctag ccaaccaatc aaagaaagaa tcagcccagc aaaaattggc ttcttcggac
     4141 catattgatc cagcattttc ccggaaaaag gagaaagcaa agcaccaacc gctgcgccgg
     4201 gaagcatcgc taatccagcg acaaaaggac tacttccttg aacgatctga aggaaattcg
     4261 gcaagacaaa agatacacca agtaataaaa actgataaac taagaagcca atcaaaaaca
     4321 agcggaatgt tttatttgaa agaatagaca gtcggatcag tggatgctcc acttttttac
     4381 ttcgatagta aaaaaggaac cagccaatac cgccgatgat taaagcaatc cagctggaaa
     4441 ctgttcccaa cgtactcaaa aatgttagac ttccactaaa caaaagacaa attcctaaaa
     4501 cgcttatcca atccaaataa ccactttttt gtactgccat ctcgggaata gcaaaccagc
     4561 cgataatcaa agaaagaaac aaaacgggca caagaaacag gaagatatga ttccatgtaa
     4621 aatgtgaagt cataatgcct ccataagtgg ggccaattgc tggagcaatg gccgttgtca
     4681 aagtaccgac acccatcatc gcgcctcgtc gattgagggg ggcaaatgtc aagataatat
     4741 ggaacatcaa cggaagagcg atacctgtcg ctgcaccttg gagcaatcga ccaaacaata
     4801 ggaccatgaa ggtaggagag aagaaatcga tcattatacc tgccaagaaa agcagatttg
     4861 aagctaaaaa gagttttttg agactaaaat tgcgattcaa ataagtagac agcggaacaa
     4921 tgatcgaaat catcaaaaga taaatcgttg ttacccattg gacttgtgca gtcgttaaat
     4981 caaactgtct gataagagtt gggaaagtta cattcatggc cgtctcgatc aatacgcccg
     5041 caaaagacat catccctgtt gcaattactg caggtactaa aagcagctgt ttttgttttg
     5101 tcatttacat cacctctaaa aaatttcgta aaaaaagaga gtgatttcta ttataaaaat
     5161 agaaaccgcc tctctctcga cacgccgaaa cgtgttatct gtacgattta tttacttcac
     5221 ttattctagc acaaactgaa aaatagtgtc aacacgatta gccaagtcac tcaaaaagag
     5281 gtatgataat aaataactaa atggaatttc gcggaggaag aaaaatggaa aaaattgaat
     5341 ggcgtaaaga caagagctat agtatgaaaa aaagcccgca aatactagag gttcctaaaa
     5401 aatcattctt tagcatcaga gggatcggcg acccgaatca ggaagacttt aaacgaagag
     5461 tagcctgtct atatgcagtc agctatgcaa tacgcatgtc gcctaaaaaa aattggctga
     5521 ttcctgatta tcagatgtat actgtctatc cactggaagg acaatgggga ctgcaagaaa
     5581 agtatttgca tgaaccagtg atgaaaaaag aacatttttc ttatcaattg atgatccgac
     5641 agcctgactt tgttacagaa gcgatagcac aagaagccat tcagcgttct agcaaacttc
     5701 cggaagactt gaaagaacaa gtagtattca aaaagatgga agaaggtctt tgtgcccaaa
     5761 tcttacacgt cgggccctat gccgaagaac cagcaacgtt tgagaaatta gaagcattca
     5821 tcgcaaaaga aggctatgaa agagcttcta aagaacacaa agagatttac atcagcgatc
     5881 caagaaaatc agcacctgaa aaaatgaaga cgattttgcg tgttaaaata gaaaaaggtt
     5941 agcaacctga atgaaaacaa aaaataaaag taaaaaatac caaaatatga agaaatatta
     6001 cttatctttt gctataatca acattgagag gtgtctaata tgaaaaagaa acagcgacaa
     6061 gcactgatcc gccagatcat tacagaacaa cctattggga cacaggaaga gctgcttgcg
     6121 cggctgcatg aagcaggcgc cgatgtgact caagcaacga tttctcgaga cattcgagaa
     6181 atgaagttag taaaaagtca aaatgaaaac aaaatagtac gctatacatt atttaaccag
     6241 ccatctgttt ctttaaatga agaacgtttg cgtacagcaa ttagacgcga ggttttgcgt
     6301 atccagtctg ttcagttcat ggttatcgta ttgactgaac gaaatggtgc cgatgtggta
     6361 acgaattggc tagatgaagt ggcttaccct gaagttgtcg gaacgatggc cggtgtagat
     6421 acattcatta ttatttgccg ctcagaagaa gaagcacagc gatttgcaga aaagctggaa
     6481 aaaatgaggg aataaatgag gaggactttt atatgaaaga tatgaaagcg ctgcaaaatg
     6541 gatcggatat tcgaggaatc gcattaccag ttgaaggata tgaagtaaac ttgacgacag
     6601 acatggtaaa aaagatcggc tggggactag caaactggat aaagaaaaag aagaaatcaa
     6661 ccgatccaaa taaaaaatgg acgattggga ttggtcatga cagtaggata agcggaccag
     6721 cactgaaaga ggcgttgatc caaagtctga aagaacaagg gatacatgtc atcgatttcg
     6781 aattagctac tacgcctgct atgtttatgt ccactcaatt tgaacagttc tcgtgcgatg
     6841 ctgcggttat gctgactgct agccatcttc cctattatta taatggaata aaattcttta
     6901 cctcagaagg aggagcagaa aaagaagata ttgcttttat cctatcacag cagcaaaaaa
     6961 taaaaagcga acaaactgga agcgtagaaa aagcagacct tttgacacct tatgcgcaag
     7021 atttagtcac aaaaattaaa aaggggattg gaacactaga aagcaaacca ctaaatggtt
     7081 ggaaaatcat tgttgatgcc ggaaatggtg ctggtggatt ctttgctgaa aaagtattga
     7141 atagcttagg tgcggattca acaggttccc aatttttgga accagatggc cgatttccta
     7201 atcatatccc aaatcctgat aataaagaag cgatggaaag tatcaagcag gctgttttag
     7261 caaatgaagc agatcttggg atcattttcg atacagatgt ggatcgttct gcagttgtca
     7321 gtgcttctgg aacagtgatc aatcgaaata atttgatcgc agtattaagt acaatcgtat
     7381 taaaagagca tccaggaaca agaatcgtga cgaattcccc tacttcttct catctacaaa
     7441 gattcattga agaaaaagga ggcatccaag ttcgttatat ttccggctat cgaaatgtaa
     7501 tcaataaagc attagaactt aaccgtcttg ggaaagatac acagctagcc atcgaaacaa
     7561 gcggacacgc tgcattcaag gaaaactatt ttctggatga tggtgcatat gtcatcgcaa
     7621 agatcctgat gcttttgcca gaattaaaaa gaaaaggtat cacattagat gaacaaatca
     7681 aagagttgaa acagcccgta gaagtacaag aaatccgatt aaaattgttc agcgatgaac
     7741 cacgcgaaca aggaaacaag atattagaag aaatgaagcg actgttggaa gaagaaaaag
     7801 ggatgaactt cgacccggaa aatgaagaag gtattcgata tgatctagaa gagccatacg
     7861 gaaacggctg gtttttgatc cgtttaagct tacatgagcc gttactagta ttacagatag
     7921 aaaatgatga attcggaaag aacaagttgg cgttagtaaa attagcaaaa ttattcggac
     7981 atttttctga tcttgaatca ttaacagcag aataaaccag tctttttgaa aggctagttg
     8041 cttggacggc aaaaaaagtg gtatggttaa atcgagtgct ggtagggaga ccagcaaaag
     8101 gaggaaaaaa tggtaacgaa tatggttatt tttttaacag tattggttta tggggtcaac
     8161 tttctggtat atatgtatct taaaatcaat catataaaag attatgtaga aaagattgct
     8221 atttattttg gaacaaatat gacgctgttg ttcacgagta gtattttttt gttttttgga
     8281 aaaatagtag aagacggcat tctggtattc gaataagcag aatttttgta gaaagcgcct
     8341 tacttgtcat acactataat tatagccaag tagcaaatgg tcaatcgaaa ggagcagtac
     8401 aatgaaaaaa gcatacgaaa cagcaatgat caaccatggc gggcgcaatg gagaagtcga
     8461 ggcaccaaat ggctcgatgc atatgaaaat cactcctcca ggaatccatg cagaaggaac
     8521 aaatccagaa caattatttg cagcaggtta tgcttcttgt ttcaatgggg cggtacaaca
     8581 tatgatcaaa gaagcaggaa tgacagcaga gtccacagta aaagcacgtg tctctcttta
     8641 taatttagat gatggcggct atcagatcgg tgtagtatta gaagtgcata tcgatggcat
     8701 cagcgaagaa gaagcccaaa aaattgcaga agatgcgcat gaattctgcc cttactccaa
     8761 agcaactaga ggaaatatcg atgtagaagt aacgattgtt tagaagaata aaggaaatcg
     8821 aaccagacta aaaacgtgaa aggaccgctt tttgtctggt tttttttgac aaataaagca
     8881 gatgatttgg agaatagaca attatcggtt atcatatttt tgtaccaatc ggtaggtaaa
     8941 aaagaagcga gggaaaaatg atggaaaaat atcaaaatat tgtgatcggt tttggaaagg
     9001 gcggtaagac tttagcgaag gcgttagctt caaaaggtga atcggtttta gtcgttgaaa
     9061 agtcaacacg tatgtatggc ggaacatgta tcaacatcgg ctgtattcct tctaaatcat
     9121 tgattttcaa tggagaaaga ggaatcgact ttacagaggc tgttgctcgg aaagaaaaat
     9181 tgacgggcat gcttcgcgcc aaaaattatc atatgatcag cgatgaggca actgggacag
     9241 tgatggacgg tacagcacgt tttctttcta accatcaaat cgaagtgacg aataatggtg
     9301 aaaaagtgat tgttgaaggc gaacggattt tcatcaatac tggttctgaa ccaatcattt
     9361 taccaatcaa aggattgaat acaagtcgct acttgattga ttctacgcaa gcgatggatc
     9421 aggaacaatt accggaaaaa ttagtgatca tcggggctgg atatattggc ttggaatttg
     9481 catcaatgtt caatgaatac ggatctaaag ttgtcgttct tgatgcccat tctgaatttc
     9541 ttccacgtga agatgaagat atcgcgcaaa tgattttaga agacatgaca aatgcgggaa
     9601 tcgaattcca tctaggtgta tctgtagatc aagtagcaga ccaagaatca acagctgccg
     9661 tcacctttac agaagatggc caagaagtaa caatccaagc gtcaaaagtt ttggctgcaa
     9721 ctggaagaaa accaagtaca gcatcacttg gattagaaaa tacagatgtt aaactaacag
     9781 atcgcggagc aatcgctgtg gatgaatacc ttcgtacaga tgcagacaac atttgggcga
     9841 ttggagacgt caaaggcgga ttgcagttca cttatatctc tctagatgat tatcgaatca
     9901 ttatggatca gttgaagggc gagaataaac gaacaacgaa taaccggaaa gctgtgcctt
     9961 acagtgtatt tatcactccg actttatcca atgtaggttt aacagaaaaa caagccaaag
    10021 cacaaggcgt caattacaaa ttattcaagt atatgacaag cggtgtccct aaagcacaag
    10081 tattagaaga tcctaaaggt gtattcaaag ttttagtcga ccctgaaact gacttgattc
    10141 taggggcaag tatctatgcg gaagattctc atgaagtcat caacttgatt tcgctagcta
    10201 tgaatggaaa acttccttat acgttattga gagatcaaat ctattctcat ccgacaatga
    10261 gtgaagctct aaatgatgta ttaaaataaa taacgaatgg agaatccacc atgttcaata
    10321 ataaaaatac agcagtagtt ctcactgacc cgcaagtcga gttcttgaaa ccagcaggcg
    10381 gtggctttgg tttgacaaaa gatatcttag aaaaatacaa tacgatcgaa aatatgattg
    10441 aaatggtaaa acaagcaaaa gaaaaaggat acaaactctt tatttctcct cattattttt
    10501 acccacatga ccataaatgg caatttggcg gtgcaggaga acatatgatg cttgagcagc
    10561 agatgtttgc tagaaaaagt caatatgaat cagtggaaga aggttcagga gccgatttta
    10621 tcgaagaatt gaaaccttat ttggatgaaa atacgatcat cagctctcct cataaaatct
    10681 ttggaccaga aagcaatgat ttggcgctcc aattgagaaa aaatggaatc gacacagtaa
    10741 ttcttggtgg aatgaacgga aacttgtgta gcgattccca tatgcgtgaa ttggtagaga
    10801 gtggattcaa tgttgtggta gcgacagatg caattggtgc tcctggccaa gaagcaatgg
    10861 atgcagcgtt gacgaacttt ggctttattg cagatcaagt gatgacaaca gaggaagtat
    10921 tagagcaact atcataagat aggaattgct tttgtcctcg cagttcttga atcaatgaac
    10981 atctagctat atgagaacag ttttatagtg agggctgtgt cagataattt ggcacagtct
    11041 tttttaaacg attaagaaga aaaaatgatg aatttactgt ataatatagg actatgagaa
    11101 atgaaaaagg agaatatcat tgaaaacaaa ggaaaagatc ttggaagcga ccaaagatct
    11161 tatttataaa aaaggctatc atgaaacgtc aatccgagat attctagcag cttctgatac
    11221 aggaaaaggt caattttatt attacttttc ttcaaaaaaa gaagtttgtc tagcggtgat
    11281 ccatgcgcat atggacgtat ggcagacaga attgttcgaa gacatcttaa atgctggaaa
    11341 acagccagaa gaagcattag aagaaatgtt ggactggatt ttcgctgatc atgagacaca
    11401 gatcacttat catggctgtc ctgtaggtaa tttgattatt gagttgagta cagtggatga
    11461 agaataccgt ctgttgctac tagaattagt caatcaatgg gtcaagtata cgaaacaaaa
    11521 tatcctggca ctttctgaag aaaaactgtc cgatgaagaa gcagaccgtc aagccaaagc
    11581 gttgattgct gaaatccagg gaagtatctt attgttgaaa gtcacacagg atctatcact
    11641 acttaggcag aattttcaat tgatcaaaga aagattgtta acttcgcaaa aggttcttta
    11701 ataattagag gttgtgacag aagtggtcag cttcaagaaa taagaaggaa tttacgaaaa
    11761 ttgcttctca aatttttgtg aaatttcggc ttatttttcg aagaagctac ttctggaaca
    11821 ccgtgtatta gaggttgtga aatcagcgct ttgacctgag tattagagaa acaaacggca
    11881 aaatagttcc tcatattttg ccgttttttg agctaatacc gaaggttagc tgattgaaca
    11941 ccgtttagtg gagaggttgt gaaaaagctg ccctgcatca agtaataaga acagccaaat
    12001 aaaaatagct gctcatattt ttcgtttggt tgggcttatt accgcagatg caagcttttg
    12061 aacaccgttt aaggaagagg ttgtgaaaaa gtcgcttagt ttcgagtatt aagaaaaatt
    12121 ttgtgaaaat agctttctac atttttgcat aaatttggct taataccgag aaactggctt
    12181 ttgaacaccg tttacccaga ggtcgtaagc ctgccgtttc actccgagtc acaaggaaca
    12241 atttcaaaaa gcagcttctc atgtttgttg aatattgtga cttgtgaccg aggagttggc
    12301 aggagaatac cattcactgg agagtttgtc acttgtcaca acttttttag ttctacaaaa
    12361 attgaaagcg ttttgttggt gcgaacttct tgttgcagtg tatgatagaa aaaaagattg
    12421 ggagggatta ggatgtgtgg tcgttatttt tttgatctag agtcagagct ccttcagaat
    12481 tattatcgag aagcccagac gaaacaaccg aagcaggcag cagaattagc agctggagaa
    12541 gtttttccgt caaatcttgt tgtgacgtta agaaaagagg aagaaaacat cctcactccg
    12601 gaaatcatga agtggggatt taccggattt aaaaaaggac aattgatgat taatgcccgt
    12661 gcagagacag tagaagaaaa aaagaccttt catcaaccat ttttgcaaaa tcgttgtgtt
    12721 ttcccaatga gtggaatgaa gaaaaagaca aatttatgtt ttcaaataag gaaaaaatag
    12781 tgtatattgg cggtttttat cgtagccatc aggatgaaaa aatggcagaa tcaatcataa
    12841 tgactactga acctaaccgc acagtcgcac caatccatga ccgaatgccg cttgtcttga
    12901 ctgaagaaca aatcgaacct tgggtaacag atatttcttt tgcgcgaaaa atcattactc
    12961 agcagatgcc tgaattagta atggagaagg tataacataa tcgatttttc aaagaaagag
    13021 cggcaaaaaa cgaaaaagac ttcagcacag atcccaaaaa caaagagaac agaagaaatg
    13081 ctcataagct gcatatactg catctatagg gtcacagtcg acctttctaa tgtatagctt
    13141 ctatttgttt tttactcgtg ctgcgagtct tttttattta tacctaacga tgtttatcat
    13201 tatgactctt tgaattcttg gaatctaaaa ttcaaagtta acgactggtt ggcagttgta
    13261 tattctctga atttatagat aagaggttgc catttatcca cattgatatg agttggatca
    13321 tgtaaaatcc cttcttctac aaaaatagct acgatctcac gttctacaat agcaaagtct
    13381 tgtctagttg aaattcgttg aaccaatgtt tctatttgaa gcgggcattc tttgatccga
    13441 acagttgaaa cttcttcacc tgctagtttc gtgaactttc ccaattgaaa tttgtcagag
    13501 caaaaggaat agccagcttt ttgtttataa tcgggcatga taggatggcc tgttgtcttt
    13561 gaaattttct cccaaagcgt tttatctgca aaattgaagg tagcgggggg ttagctatag
    13621 tatttgggta gcttttggat ccataggttc aatgtttctt ggattatttt tttagttaaa
    13681 gaaaaaatga actggctaca atttatttct atttatatcc aataagatat actttaaaca
    13741 aaacaatttt ctagatagtt tacaaagggg aattttgcgt tacttagtgt tatatagtat
    13801 acttttatta agggagtgat gataatgctt gttacaaaat ctagattaca aggaagttct
    13861 gtagtggtaa ctttaccttc tgataacgga aagaaacctt cagaaaacca agaatatatc
    13921 gttgtgtatt ctgatgatgg aacaattacg ttagttccaa aaattgaaga tccatttagt
    13981 ggtggggaag aggccgagta ttatgagaaa gacgaatggg aagatttaac tcctgaaggg
    14041 agagaaattt tatagtgtca gaagaaagaa tttatattcc taaaaaaggt gatattgtat
    14101 ggattgattt tgatccctcc gtaggaaaag aaattcaaaa aagacgacca ggactagtcg
    14161 tctctcgtta tgaatttaac cgtaaaacaa tgttttcggt catatgtcca attacttcca
    14221 ctataaagaa tttaccgaca cgttactcat tacctgaaga gctagatata aaaggacaag
    14281 taattattac acaattaaaa tctcttgatt ttaaggaacg aaaactcaaa aaaatagaaa
    14341 acttaccatt gcaagacatg gctaaaattg atcagattat acagtatatg ttttaagcat
    14401 tgtaagtaaa ctctataata tttttatatg ctaaacataa cgaaattaaa aaaaggccaa
    14461 gtaaatgtcg ttcattctac tagtgtggtc gatggcatta atttccgtat cttaaactaa
    14521 agaatatata gcattttaaa cgaatgattg aggtgatttc ctcaagtcat tcgttttttt
    14581 gtgtcacaaa acttgttttt tcacgacata tcttaacgta tacgaaaagt cgcgacaata
    14641 ctttaacaga aagaagaaaa agaacaactg acagttttag tcctaaaaaa tctaaactct
    14701 ttagatatga gtaatgtcat tttaaactat atcgatgctc aaaaacgtaa aatttgggat
    14761 caagatctgt ctaggaaaga atttctatag tttaactgaa taacacaaaa aggcatatca
    14821 tgcgacaaga aaaacaatga aaagagaaat ttgccatcac tggaacatcc atacagaaat
    14881 tagcatagat tctgaaaaat ctaccgctag tttttattta gttgttctaa cgacaccaat
    14941 acttgtaatg atcgaaaatg tgcaattggg tcagatagtg aaccaaagta gaatctcaaa
    15001 gcgacaatta tgaatgtaaa agtacctttt atgattagtt tattctctaa ttgattacat
    15061 cccgtataat taataaaatt actttaccga ttacacgatc ttatgtcagt agagctttta
    15121 ggtacactat caatacagtt cattccagta taatgtaagg ttttttttat tttgagtcac
    15181 tttttgtcaa tattattatt tacaatacct tctataataa aagttattta aggaagtgtc
    15241 tatgaatgag taaaaattct aaaggattcc taaccatctt attagctttt atagggtata
    15301 tgttggttgg gctgctaaaa tcatacagta atgagttgct gaatttttca acatttatta
    15361 atgatacatt agttccaagt ttgtttttca ttgtattttt tgctgttggt tattttataa
    15421 taaagatatg atgactaatt tagctcaact attccagcgt cagctgaaga tattgcaatt
    15481 cccgattcct taatcattta tctggatgag acagaaagtg aagttgcaac agatgtgcat
    15541 gtagttgagg ataaaaatga tagtttaaaa attaatagtt cagatacttt actaagagta
    15601 agtcctatct tttcagctgt tatttagatg caagtagcaa ctaagttagg tagtactcct
    15661 gcaatggata ggtatttgtg tgttcgatat ataagtggtc gaagtatcaa ggttatgtat
    15721 actggatggg agatagaaga gttaaaaatt ggaggtcacc gccacaaatg gaatttagat
    15781 ttagaggtac cttagatttg gtatagttat taaacacaag atggcctggt ttgtagggaa
    15841 agtcgaagag tatttttcca cttctgcgcc cctttaattt ttctagtaat gccgtgaatt
    15901 tgtgattaat tggaaatatg aagaaaggag agtctatgaa aacaacacta gttctattct
    15961 ataaaaagca tccttatttt acacttctga taaatatatt gttggctagt gttatcggga
    16021 tttctgttga atatctaata aataaagatt tcataggttc ttgtttttat acggctttat
    16081 ttcttggact tcttgaagca ttttccattt ataaaaaatc aaaaaaataa aatagattgc
    16141 cgtaagagat ctttttcatt tcattttttt ctgaaaaccc gttgtttctg tcagtgaagc
    16201 agcgggtttt tagatttatt gtctttagac ctaattgagc gcgccgagcg attgaaatac
    16261 aaaaccactt gctatgcggg tggagcaata aagggaaata gtttagcccg tacaaagtag
    16321 atgtgtaaat accacattgt attcacacca aagtatagaa gaaaaataat ttataatcaa
    16381 tatcgagcca atattcagga gatcatcaag agattgtgca aatctaaaat ataaatttgg
    16441 gtatcgacac ttttgggtgg aaggatacta tgtgacaaaa gtaggacaaa atgaagcgac
    16501 catcaaaaag tacattcaag aacaagaaaa acatgatagt gcgttagata agctgagtgt
    16561 acgagagtaa gacgatcctt ttaagggcta aggagtagta cataaacctt ttaagaggtg
    16621 ggcaaaactg gcaaaggcaa tatggcttga acataaaata tgaaagccag cgtctttagg
    16681 cgctggccgg tgatttgagc ttatagctct agagaaaacc acccttttga agggtggtta
    16741 tgattaatga ctttagtcag ttttgctcac aaagcgtgtg gaacaaaaaa cgggtgtttc
    16801 tacgggtaga tatttatttc ttgaatggag gtgtcccata catttttggt gttactggtt
    16861 ctaattttgg tgcagcgcct tcgatcttag gttctttcaa ccattgatat tcgccttcgc
    16921 catccagtgc tttgccacta gcccaagaac cttcactact ttggtctccc tctgagaagt
    16981 tatagaagtc ataagcaatg tcttttcgtt ctttgtcacg cgggaaagta cttgggacta
    17041 agattgaacc ttctttttct tctaattctt tcactgcaca ttcccataga ttttgatgat
    17101 agctatctct tgcaaggaga acagacagca tatcttttac gccacgatca tcgatcattt
    17161 cgtaaatacg tgctacttga agtcttcctt gtgattcggc atttaaatta gctctaaagt
    17221 ctgctaacaa gttgccactc gcaatgatat aggcaccgct ccatggattg cccacgctgt
    17281 cagcaggacg aggtcctaag ccagctacga tcgcgtgctg tggattcatt ccagagataa
    17341 tggcaccgat tgttggatct ttttgcatcg ctgcttcttg atcttcaaca ggcgcaccct
    17401 ctaataaacg agcaaccatt gtcgccaaca tttccacgtg gccgatttct tctgttgcaa
    17461 tgtccatcag catatcttta tatttttctt ctcctcggca gctccagcct tggaacaggt
    17521 actgcatagc tacactcatc tcgccatatt ggccgccgat cagctcctgc agatatttcg
    17581 cgattaatgg attcggacga tctggttttg cttcaaactg caattctttc tggtgtctaa
    17641 acatcaaaat tcctcctaat ctatttttaa tacattctca ttctgctacg aaagattaaa
    17701 aaattcaaag aaagcgctcg cgaattatat aaagtattgg tatcattaat aattttttta
    17761 gaatcatacc ttataaattg ttattttcag aacaaaatga tatcgttata ttaaaaccgg
    17821 catcggttac attaaaattt ggaggtaaaa tatgaaaaaa ttattgttta cagggttgct
    17881 ggcaagttca gcattgtttt tattaggagg atgcggatca agtaatgcaa gcgatgccag
    17941 ttcaagtgca gcaaattctt ctgaaaaaac aagtgatgga agaaaaaata ttgatttctg
    18001 gtccttttgg ggatccggtg cacgaaaaga agctatcgaa gaaatcattg aggatttcaa
    18061 tcaatcacaa aacgagatcc atgtaaatta taagtatcag ccatggggtg acatctggac
    18121 taaatcttta tctgcaataa cagctggaaa tgcacccgat gttattgtac aggacataaa
    18181 ttccgttgcc caaagagcag aagcacagca agcaactaat ctctccaaat atgtagaaaa
    18241 agacacttct aaggattttt atccgcagct ttgggataca gtagaatatg aaggtgatcc
    18301 ttatgcgatc ccattcaata cagatacaca agtcattttt tataataaaa agttatttaa
    18361 agaagctgga atcagtgaac aagatctacc gacaacttgg gatgaattag aagaaacagc
    18421 acgtaaacta gataaaaaag aaggaaaaga atttacacgc atcggttttt atccattatg
    18481 gaatttaggg gctgatgtat gggcgctaaa cgcagataac gggactagtt ggtttgacaa
    18541 agatgaaaaa gtcaagattg atactaaaaa taaagtggaa gccttggagt ggatccaaga
    18601 ctggcaagat tattatggga aaaatacgat caataaatta gaagccgaat ttgggtctgg
    18661 tgtatctgat ccatttattt ccggattagt agccatgcgt gcccaaaata tcaattatta
    18721 ctctagtttg atggaaaatg caccggatga ttttgatttt ggcgtgatgc agctcccaga
    18781 aaaagaagaa ggttcaggcc attggtcgtg gggtggcgga ttcgtcttgg aagtaccata
    18841 cggagcaaaa gatcctgagg cctcttatga attcatcaaa tatctttctt ctccagaagt
    18901 acaagaaaaa ttcggcgaaa aaagttttga tatcatggcg agcaagacag ccaatgagaa
    18961 tttagtgaat aatgacaacc taacggataa aggaaaaatg atctatcaaa tggcggacga
    19021 aaactttaaa aatacggtga tcacaccagt tcctttagat gctccggatt acacgacatt
    19081 agtgaatgaa cagattgacc agattctttt aggaacaaaa tcaccaaaag aaggattggc
    19141 agatgcacaa aaagcagtag aaaacttagt caagcaaaat caataatcca tttttgactg
    19201 tctaggtaca gaggaggcaa gaaaatttga agcgtttatc tatccgaaag aaaaaagaag
    19261 caagatgggc ctatttattt atctcgcctt ttattatcgg gttcttggta tttatgctag
    19321 ggcctatgct tttttcagtt attggtagtt tcaccgatta taatttgaca tccaagatga
    19381 atttcattgg tctagcaaat ttcaaaagaa tgttcgttca cgatgattta ttttggaaat
    19441 cgttatacaa caccgtttat ttcgtcatct tcaatgtacc gctgacgacg attttcagtg
    19501 tgtttttagc cacagtactc aatcaaaaaa tcaaaggaat cagtgtattc cgtacagctt
    19561 tctatttacc ggcagtctta tcaggagtag cagtctacat cttatggatg cagctgcttt
    19621 ctccatctgc aggattgatc aacacatttc tgggctggtt ccatatccct ggaccagctt
    19681 ggctgtttga tccacaatgg acgaaacctg cgttgatttt gatgaaaata tggagttctg
    19741 gaggagcaat gctactttac ttagctacat tacaaaatgt tcctagatct ttatatgaat
    19801 cagcagaaat cgatggagca ggcgtttggg gaaagttcaa aagtattact ttgccattaa
    19861 tcactcctat tattttttac gatgtgatca cctctacgat cggttctttc caaatttttc
    19921 aagaagctta tgtcatgacg aaaaatggaa caggcggacc tgcaaattct ttgctttttt
    19981 ataatctgca tatgtggaac aaggcgttcg tagcttttga tatgggttat gcgatggcta
    20041 tgtcaatgat cctgtttctg atcgtgttgg ttctgacgtt tgtcaatttg aagcttgcac
    20101 ctaagtgggt ctattattct ggaggtgacg gcaaatgatg gattatttca aaaagaccag
    20161 tgtgaatcgg caaacaaaaa aaatactaag ttatgtcctc atgacagtaa taggaatcat
    20221 tttgatcatt ccattgcttt ggatggtgtt tacttcattg aaaccaatgg aagaaatcgt
    20281 tcgttatcct ccgacctttt tcccagaaaa aatcgtatgg gaaaactatc tggatacgat
    20341 tgccgccttt cctttttggc gctatgcaag aaatacatta ttcatcactg tgctagtagt
    20401 gatcggtaat gtcctttcaa attcttttat tgcttatgga tttgcgaagc ttgattttcc
    20461 tgggaaaaag ctgatgtttg ctttggttct ttctacgatg atgatcccgg ggtttgtaac
    20521 gatgatccct caatatgtat tattctccaa gatcggctgg gtaggtactt atttgcccct
    20581 gatcgttcca tcgttcttcg gcaatgcgtt caatatattt ctgatgcgtc aattttactt
    20641 atcgatcaat aatgaattga tcgaagctgc tgaaatcgac ggagcgaatc atttgtatat
    20701 ttggagtcat ttgatgcttc cattgacgaa acctgccttg attaccattg cgatcaattc
    20761 cttcaacgca gcttggaatg atttcttagg tcctctgtta tatatccaag atcaagaaaa
    20821 atacacgtta cagattggct tgcaagtttt tcagaaccaa gcaacgacac aatggaatta
    20881 tctgatggca ggagcaacac ttgtcttgat cccgacgatt ttgctgttct tttttgcaca
    20941 acgttatttc attgaaggga tggatttgac aggaggttca aaaggatgat gaatcgatcg
    21001 attggtaaaa aagccaatga ttatttctta gaaatcattg aatggattcc acgtcttatc
    21061 catttacagc tactatggtt cctgtgcgtc ttgcctgttt tcacattagg aactgcaagt
    21121 cgaacagttc tgtatatgat ttatcattac aaaaaaaatg aagagaaaaa gctcggttca
    21181 ctattctgga aaaagtttcg tgagaacttc tctctttatg gaaagcaaga tagtttagca
    21241 agtgtttatt ttcttcttct attgatcgat tatcagattt tccgctattg gggtggggga
    21301 attggctata cattgatgta tactacgttg tttttgcttc tattaagcgc gcttctcttt
    21361 agttacaaaa tcttgcttca actggaacaa aaagaagctt cttggattac tgcatttttc
    21421 ttgtttttta atgatttcaa aagcgcgctt ttctatttgg caggcacgtt gatccttctt
    21481 gtcgcattct ggtttgcagg accaatctat tttgctttat taggtttcag tttcttgttt
    21541 tattttcaag tcctgctttt tatccatcgt acgcaagaaa aggttcttaa aaaggaggaa
    21601 taacatgttg cgtttgattg ctaaaatcga tgatagtatt atcaacaagt tcgccaagca
    21661 acggaaaacg gatagtcgaa aaatcaattt tttgaaattt atcagtaata tctctaatgg
    21721 tggttttatt tggttgctcc ttgctgctgt tttagtcttg atacctgata ctagagaata
    21781 tggtctagcc attcttatcg gcagtttgat ctattttttt gttggtttgc tttttatcaa
    21841 aaaaacgaca agacggaaaa gaccttatga aaaaaatcgt cggcttgtcc tttacacaag
    21901 taaaccgaag acttcttctt ttccttcagg acatacagcg ctagcctttt tatcagtagc
    21961 tgcgttgttc gaattaagtc cagttgcagg aatattagcc tttttatttg cttgtttgat
    22021 cgcttattcg aggatttttt tacttttaca ttatcctact gacattttag gaggagctat
    22081 tttaggaagt gttattggca tcctatgcgc tgccgttatc tgaattaatt gtacgaataa
    22141 agcatgagtg cgtaaatgcg catttgtgct ttattttttt gtttcgagga aagcgtagtt
    22201 gtttattcat ttgtcttaat aacttaagtt ttgttaaatg agaacgttat aaaattttat
    22261 aatttaattt taataataaa tgttgtataa ttggtgtttt taactaaaaa ggatatcatt
    22321 tgatttaaaa ttaaaattaa attaaattat aattagatgg gcattgtttt gttgattgtt
    22381 gtgaaagaag acaaatattt ttgaaaggag tataaggatg tgaaagggtt aaaattgaag
    22441 cttttgcagt tagtaactgt cagtttgcta tttggaccat atttccagtc agtctatcat
    22501 atgacgaccc tggatgtagc tgctgagtca acagaaacaa aggaggatga ggtattctta
    22561 gatgaggact atgcaaaaat tgaagggaag tatattgaaa aagaagaaac ccttgaatgg
    22621 catctggctt ttgaaaaaaa ggaaagtgcc aatgaaggta gaatacgttt agcaatcgat
    22681 gcggcagccg ccgggattgg taccgtaaaa aacgttcgtg gaacaggtct atcctcctat
    22741 gatgaagatg gagaagacct aaaagtcgag acgatcgatg gtcaagaatg gtatgtcgga
    22801 aaagtttatt caaaagaagc agaaaccggc acattgattt ttgaaacaga aaagatcccc
    22861 gatgtgaacg aagggtaact acctcttcaa gtggtggttg atgaaagaat agataaccaa
    22921 gaattacaag aaaatgaaac tgatacagaa gattccgctg aaattcaacg tagcgaagaa
    22981 aatgagatgg aaaagctgga cgaaccaatc gtacccagcg gtcaagcact ccagcgcatt
    23041 caacgccagt tattcaacgg tattttggag cgtcttgggc caacagctac gcaagacccc
    23101 tatgaatata tctatcctag cggagaagtt gaaaacgaac agcatcgcta cccgaagttt
    23161 acaacgaatg actatacaaa agtgttagga aattggacac aaagcaatga acgctatcaa
    23221 ggagacaaag gctcgccata tgacggagag aacttgatcg atgatagtga ttatacaaac
    23281 gggggagcga actggcgaaa ttacgactat gctactaata atggatcaac tgcaggcgaa
    23341 gaagatagaa acgttccagc tcaaaccgtt cagctttggg gaaatgaacg gaattttgaa
    23401 aacagttact tggattataa cggggcgtac atcaaaaaat gggtagaacc tgttctgcca
    23461 agcagcacag catctgatct acatcctgaa gatgcaacaa ccctttacaa tgtctatcta
    23521 gatgtcatcg ggggcgagaa aaaggaaatc agtccaatcg atatcgtttt tgttctagat
    23581 aagtcagcga gtatgagtga attaaccgct gggaccaata gtcaaactaa aaatgctgcg
    23641 ttgattgagg cagtaaacga aatgagtaaa gatctgctct ctgacccgag tctggatatt
    23701 cgaatcggta tggtgaattt ttaccataat agtacagcta tcaataacca tgagcaaatc
    23761 agttcggaca tctttccatt gacaaatgat atcaatcgtt tgacgggaag tgagaataca
    23821 gcattaaatc gtacaccaat cggaggaact ccgcttacac tagggcttaa aaatggctat
    23881 gaaacattgt ataaagacaa tggcggagaa aatagaaatc cagaaaaaat cctaatcgtt
    23941 gtgggagatg ggacaccgac cttcagttat gcaccgattc agtcaagtta tcgtacgagc
    24001 actaatggag cttggagcaa ctggactgtg atggaagata agattgctga agataatgac
    24061 gttttgttca gaaattttga ggagttttct gggaatactt ctaatgcagg gtttactcat
    24121 ccagttacct atgcatctga ctttaaccgt ccagaagatg aagtaaatgt acactatcgt
    24181 tatggagagg taaaagaagg agataataaa gcgactcact gggttggtga tggttcttct
    24241 aataacaata cgaatggcag tcctacttcg caagaaaagt catctgcgat caacacagtt
    24301 gcttatcatc attggctgaa aaacaagtat caagagaacc cgccaagtat cttctccatt
    24361 ggtttaggaa tcgatggaaa cgttagcggg agacaacgac tagatgctat tggacgaaat
    24421 gtattgaaaa atattgctga tttagaagaa gatggcgtaa caccgcgata ttacaatgcg
    24481 aacaacaaga atgacattgt tacagccttg gaggatatct cttctacctt caagagaacg
    24541 atccagcaag ccacacttta tgatgaaact ggttttaatg tctcaccatt tggagctggc
    24601 agatcggcag atattcagtt ttaccatcta gatccaggag aaaacggcat gaagtaccaa
    24661 gagccagaaa tatgggatga agaacgtcat ggacaagccc caccagaagt agtggcgact
    24721 ccgacaacgt atgtcggacg ggaaaaccaa gcttataaat tttctccgat ttctttaggt
    24781 gaaggggaaa tggtcaggat caagtaccaa gtaaaacttg atgcgggagc tcaagacgga
    24841 aatttttgca cagtgaacaa tatggcctat attcagaacc tggaggatta tgagaatgat
    24901 atcactactg gacggatgta tttcccatct tcttccattc gttacgaaca taaaggccgt
    24961 aatttccaag tcagcaagaa gggtcaaaat ggcgagccgt tggctggagt cgaatttgca
    25021 ttatatgacc aaaatccaga gagtggggaa gccgaaccaa tcgaaacaag taaaactacc
    25081 acggacggaa tagcgatctt tgaaacgaag atgccgattt taggagatga aactggagca
    25141 gtcagcgaca tattttggat cagagagatc gctggaccac cacgttatca gttagtagat
    25201 gagacgtatc aattccaaat caaaaaatat gcagccaacg aagatgagat gttaggtcac
    25261 tacgagcttg tagatgaata tacatctggt tcgagagtcg gcggaccgga aggtaaagat
    25321 ccgaattcct attatgaagg agaatatcac aagctttctg ttgtacaaga gcctaacata
    25381 gaaggcacag agtatgatga gttgtatgtc aaactggaaa tgcgaaatga attcaagcca
    25441 atccacatga atatcaataa actaattgaa ggcagtaata tgccaatcaa tggcgcagag
    25501 tttgaacttt atgaaacaga tggtaacgga ctggaaatcg gatatccagt agcgaaaggg
    25561 ctttctggtg tgaacgaagt agaggaagag aaagggagac tcacgttcta ttcagtagat
    25621 gaagacggga aatatgtaat cgtggatggt gagaaagtta ttcatccaat cggagagcca
    25681 gattcatttg tttataagga tagtgaagaa actaccaact atgcagaata caaaatcatt
    25741 gagagccaga acccagaagg tttcaaagaa cctgatgaaa atgacacatg gatcttgcga
    25801 ctttacgata atgctatagg gactatccaa ctcaagcaaa caggtgaaga aaattggcaa
    25861 tatctcacgt atacaacaga tgaagaggat cgtttatggg tagcattcac tgcttacaat
    25921 acgtttgatt atcgggagat ccgagttaga aaattagacc atgaaggcca tacattagat
    25981 ggtgcaggtt tcgatatcag gaaagtgggg gattcttcct tcccgctgta tcgagcatac
    26041 actggtaatc cgttagaacc agaagaatcg aaacgtttgc ctgggatcgg atacttctat
    26101 tctcgtgccg taggagtaga aaagtatgtc gatttaaatt acgaccaacc tctgcatctg
    26161 tctattggtg aatatgaggt ctcggaatct gtcgcaccaa atgggtatcg gctatctgat
    26221 caagtgttcc agtttgcact gaatgaagaa ggtaagttta tcattgaaga tacggtcatc
    26281 gaagacgaaa ctgctccctt gccggaaggc tatgaaatca tcgatggtgt actacaagta
    26341 accttagaag atgaactagc gccaatcgat ttggaacttt tgaaaattga cagtatgaat
    26401 agccgacgtc ttgaaggcgc agaattttca attgagaaac aaaatagtgc aggagagtat
    26461 gaaatcatcg agggaggctt ggcaccagat ccaaacgatt cttccctatt caatgcttca
    26521 gacttgttgg aaggggtcta tcggatcaag gaagtgaagt cacctgacag ctatagaaaa
    26581 cttccaggtt actttatttt agaaattagt tatcgagaag aacctgacat agaaaatgat
    26641 cgggtagttc caggaaaaga agcgggtaca ctaaaagttg agatttcgta ttatccaaac
    26701 gaagaagcag agacgcctga tctacagcaa gagttagaat atgaactttt ggagacaaat
    26761 cgaatcagat tacagcttag tgtcgggaac gatcctgaaa atccgttgcc tgctacagga
    26821 ggatccggac gattattcta tatcctgctt gctgcattct tcatggcgct tgcaggagca
    26881 gcctatggtt tgtttgtcag acaatctaaa aaggagggag caaggtaatg aaaaagctgt
    26941 tgtgtttgat gcttcaatta cttgttttac taccgcttgc agcagtcctt cttccacatg
    27001 cgatgtcggc agaagaatca ggggaagatg tcgtggaatt cgtgttgcat aaacggatga
    27061 ttcgagatat cgattataac gatcaatttg aataccatga aaatgatggc ttggctatct
    27121 ctgaggaagc aggggaaaca gcagatatca tttcacagac ggtgccacta aatggagcga
    27181 catttgccat ttacgacatg accgattatt atcatgaaaa aaaagctgct gaaaacatga
    27241 ctcctaaaga attcgtccag caaatcgctg aaacgaacag aaacaatatc cgtcagctaa
    27301 tcacagaaga aaggcttgtc caaataggga cttcggtaac aactgggaaa gatacggttg
    27361 gcggattagg agacgggatt gcacgtatca aagcacctaa gaaaaaccaa gatcgggatg
    27421 cagtttattt gattttcgaa gaatcgattg atccagaagt tggattggat gttgatatcg
    27481 atcagacagc tatcccaatt gctgctattt tgccaattta tcacccgaca gaatcaaccg
    27541 aggaactgca agagattcat atctatccta aaaatgtcgg ttatctaaga gatccatact
    27601 tcttcaagta tggacgtcaa agaggaacaa ctgaaaaagg aaaaccatta gaaggtgctg
    27661 tttttgctct atatcagatg atagaagggg ggaaatatta tttagatatg gctcctgcta
    27721 atgacttgaa aaatcaatgg atcaaaccag cagacaatga tcctttgaat gacaaaaatg
    27781 taagcaaatt catttcggat aaagagggcc ttgttacgac aggacaacgt ttcttgcctt
    27841 ctggcaccta ttattttgaa gaattaaaag gtgtggaagg ttacgagatg gatgaagcaa
    27901 gtaagagaat cgaggtcatc atccctgaat tttgggtgga tgcaaaaggc caaccacaat
    27961 atgtagtagt taacggacag gagatggctg aattagaatc cgggaaagtt ccagtctctg
    28021 cctatgaatc cgcaacacca cgtgtttata acgagaccgt aaaagaaaca acggacaaac
    28081 cgaaagagcc gagtggtcca agcaatccag gtcaatcagg aaaatggtcc gtattcccgc
    28141 aaacgaatga agcaagaacg ttgatttctt tactaggaat tcttttattg ttaggtgctg
    28201 ttttattaat aaaaaaagaa cggggagaaa aaaatgaata aaaaaatgat tgtcacggga
    28261 atgagtgtac tgttactcgt tactgcggga atagggattt tcgggaacgg aaaactagtc
    28321 aaagccgaag aagtcgcaca aaaaccaagt gaagtgacga ttacattaca caaaaaaggt
    28381 ttctcatctg ttccggaaga acgaccgaat agcggattgg tttctacgga ttttggtgaa
    28441 gaaaatattc caggagtcga ttttgatttg tttgacgtaa cggaagtata ttacgatttg
    28501 attcgagata atcctttaac accggaacga gaagacggtc ttaattctgc cgaagcgatt
    28561 gaatggattc aaaaacggca cacagaaagt tggtttttaa aatatcgact gacaagtatt
    28621 gacaaacaaa caacgaatga agctggagaa gcggtattct ctaccgtcca agtgacggaa
    28681 gaagcacctt cttctagaga taaagtctat cttttcttag aaacttattc gccagctcat
    28741 atttccagaa tcgcgtctcc aatggttgtt atgatgccag tgatgatgcc tgatatggtg
    28801 gatggcgtgt gggatggttc tacatggaaa gacacataca atacagatgt gcatttgtat
    28861 ccgaaaaacg aaatcagaga agcagataaa cagatgaatg tagaggaaag cgaccttaga
    28921 caagtaacga ttattaatga agctggagaa caagaaacga tttcttatat tgatctagaa
    28981 agaggaaaaa cggcttctta cacgatcaca gcacctattc cttatttcat cgattctgtc
    29041 cttgaaaacg gaagcgctgt tatcaaaaat tacaaaatca cagatacgcc tacagttggt
    29101 ctaacttatt atgatcagga aatagaagtg cgagccggcg agacgatttt aacaaaagga
    29161 caagattata tagtagaagt agtaagcaac gggtttgtcg tgacgatttt gacagaagaa
    29221 aatggagtag ccaaagtaga tactttaggt agattagcag atgcacgtgg aggagattta
    29281 acgatcacgt ataatttgaa ggtttccaca gaactagaag cggatgattt ccataacaac
    29341 acagcggtta ttgaaatcgg acgaaatgat gaatttgatt atgaagaagg agtagagccg
    29401 ccagagaaag tcacaacagg tggaagaaag tttgaaaaat atgatgcatc aagcagtgaa
    29461 ttgcttaaag atgcaagatt cgaattgtgg aatgaagacc gttctgaata cgcaatattt
    29521 tataaagggg agtcgccttt agctgtttat gaatcaggag cagatagaat tgagtgggca
    29581 acaagcggac aagcaacaga atttgtcgca gatggaaatg gatactttga ggttcaaggg
    29641 ttagattatg gaacctatca aatgaaagag accatggcgc cagaaggtta tgtacttcca
    29701 acaggtgagg cagcctttac tgaatttatc atctcttatg gaagctataa tgaagaaatt
    29761 cagatcgtag gagtagaaaa tccagggcca gaaagagtac cgaatatgaa acgcgggtca
    29821 cttcctgcta ctggtgggaa cgggctcttg gcattcttac taatcggaat aagtttgatg
    29881 attggagcgt acagctggta ccgtaaatct aaaatgaagt ctgaagtata agcaacaaaa
    29941 ataagctgca gcaatcggtt ttataaaggt tgctgcagtt tttttaaata agaaggtgaa
    30001 gaaaatgaaa aagaaaatag gtaatagacc tcaaacccaa atcagtcttt tattacaatt
    30061 atttatggca gtgatgtttc ttgccggagc tgcagttttt acatatccat ttttagcaga
    30121 tgctctcagc aattatttgg atcaaagaag gatcgagaat tatcaaaagc agcttgaacg
    30181 cgataaagaa gaaaaacatg agcaacaatt agcagtgcat gaaaagaaaa atcagacgct
    30241 tgctcataca tcagtaatcc caggaatggg acaagtcaaa gatccttttg agcaagcggt
    30301 tagaaatgtc caaaatccag gaaaagaata ttacgaacaa catatgatcg gagccatcta
    30361 tattccgaaa atcaatgtta gcttgccttt atttgatgaa acgaatgatc ttttgttaga
    30421 tagaggagcg acagtcctgc aaggcacctc ttttccaact ggaggagaga gtacacattc
    30481 cgtgattacc gcccatagcg gtattgctga gaaaaaactc tttacggatc ttgaagaaat
    30541 ggagcaagat gaccgattct atcttgaagt gtatggtcgg atgctcgctt atgaagtcgt
    30601 tgagaaaatt gttgtccttc caacaaaaac aaatacatta gcaattagag aaaagcagga
    30661 tctagtcaca cttatcactt gtacacctta caccgtgaac actcaccgat tactagtgac
    30721 aggaagacga gttcccttta cagaagaagt ctcttcaaag atagaacaga caaaaaaata
    30781 ccatctttat cgattactta tactccttct aggtatattg ctagtgctaa cgcttttcgg
    30841 ttattggtgt tatcgaaaat ttaaaagaca aaaacaacga aagaaaaata acagataata
    30901 gaccaattat taagaataac ataataaatt taagctgctt ggaagagaca aacgcgatta
    30961 aatcgcatat ttccagtttt ttttaacgtt tgctaaaatg acattttcca ggtaagccaa
    31021 cttgtttcac aagggcttct ttgatattgt agtagcaaga agaaagatgg agggattttt
    31081 tatggcaaaa atcatggtag tcgaagacga agagatcatt cgacaattga tcatggagga
    31141 acttgagaaa tggcaatttg aaacctttgg aacgaccgat ttcaatcaag tgttctcaga
    31201 ctttgaaaga gaagaaccac agcttgtatt actagatatt aatcttcccg ttttggatgg
    31261 ctattattgg tgtcaaaaaa tacgtgaagt atcgaaagta ccgatcattt ttatctccag
    31321 caggaatacg aatatggata tgatcatggc tatgaacatg ggggcagatg attttgtgac
    31381 aaaacatttc caaatcgatg tactgattgc aaaaatcaat gcattacttc gccgttctta
    31441 caactacaca gaattatcta gtgaaatgat gagccacaat ggcattacgt tgaatgttga
    31501 caacggaagt atggaaatca acggagagat cattgatttg agcaaaaatg aatatcgtct
    31561 attatttatt ttgatgaagc acaatggaaa gatcttaagt cgggaaaaat tgctgcgagc
    31621 actgtgggat gacgaacgat ttgtagatga caatacattg acagtcaaca tcaatcggtt
    31681 acgccgaaaa atcgaacagg caggtatcca aggatatatc gaaacaaaag taggacaggg
    31741 atatatcgtt ccctgaaagg atgagcggtt aagatgaatt tttttaaata tttgaaagat
    31801 cagtggacat tgatcttggg atggctgttt tttattgcat tgacgatctt tgtgatgtgg
    31861 ctggcgccaa acatcaaagt tgatttgagc acaattgctt atttagcttt gattgagggc
    31921 gtctttctga ttttttatct gctgggtggt tacttgagca agagaagatg gtggggaaaa
    31981 ttagccgaca tacaaaaaac ttcccctttg caaaattatt tgagtggtgg gaggacagaa
    32041 gaagaaaaac tggtagaaga atatatcaat cagctgatcc gtgaacacca agaagtaatg
    32101 caatcagcaa tcagtaatca acaagaccaa aaagattata ttgactcatg ggtccatgaa
    32161 atcaaagtgc cactttccgc ttctaaattg ctagttcgtt cgatcgagtt cgatattgac
    32221 gatcaaaagt atacattact agaaaatgaa ttatcaaaaa tcgatgaata cgtagaacaa
    32281 gttttgtatt atgcaagact cgacagtttc tcgcgggact acctcatcca agaatatgga
    32341 ctaaaaggaa tcattcagcc tgtgatacgc agtcaggcaa attattttat ccaaaaaaat
    32401 attcgctacg agatcgttgg tgaggatcat actgttttga ccgatgctaa atggatcgct
    32461 tttatcttca accaattgct tagtaatgcc atcaaatata cgccggatca cggaaacatc
    32521 attgtgagca tagaaaagga agcgcaagga gtcagccttt cagttaaaga ttcagggatc
    32581 ggtatcccag cggaagactt gaaacggatc tttgataagg gatttactgg gagaaatggt
    32641 cgacttagca aaacacattc aacaggatta ggactttatt tagcaaaaaa tctggccgaa
    32701 aaattaggta tccatttgac ggctgaatca actgaaggaa aagggacaac aatgacttta
    32761 tttttcccaa tcttaaattt ttataatgaa aaacgttaga aaatcgttag aaacgaaaaa
    32821 aagtgcttgt gttgttaacg ttttcgctga taagtttctt atcatgtgaa ataaaaggag
    32881 attggttatg gaaattttaa tagcattagt ccctatgttg gcatggggta gtattggttt
    32941 agtaagtggt aaaattggtg gcgatgccaa tcaacaaaca ctaggaatga cgatcggtgc
    33001 atttctgttt tctttagttg tctttttcgt tgttagtcct gtaatcaccc cttggatttt
    33061 cttgatcgga tttttatccg gcttagcttg gagtgttgga caaaatggac agttccatgg
    33121 aatgaagtac atgggtgttt ctgtagggct accattgtct actggttttc aattaatttt
    33181 gaatacgatt gcgggagccg ttttcttcca tgaatggaca caaacgaaag attatgtata
    33241 cggtattatt gctttagctc ttcttgtaag cggtgcgtat ttgactgccc gacaagatga
    33301 cgaaggaaaa atagatacag ataataaaat gcttgatttt ggtaagggtt ttagagcatt
    33361 gatcttctct acgattggtt atggtgtata taccatcatc gtcaactggg cgaatttgga
    33421 tgcgatgtca attatcttac ctcaaagtat cggaatgatc ttaggcgcaa gcttctttgc
    33481 tttccgtaaa gttaaagtcg atcagtttgt gtggaaaaac atgatctgtg gattattatg
    33541 gggcttagga aacatctgca tgcttctaac agtcaaatca cttggtttag ctgttggctt
    33601 ctcactttca caaatgggga tcattatctc tactttaggt gggattttca tccttggcga
    33661 aagaaaaacg aaaaaagagc tcatttatgt tattgttggt tgccttttag tcattttagg
    33721 tggtatcctt ttagggtata tgaaaacagt ttaatcgctg ttttccaacc taaaatgggg
    33781 aggaacttca atggatttgt ttcgtaagaa agagatcaat ctcaatcata cgagtgagat
    33841 gaaaaaagaa ctaaaaacgt ctgatttgat catgcttgga attggtgcga tcatcggtac
    33901 gggaatattt gtggtgacag gggttgcggc caatcaaaat gctggtccag cactgtcact
    33961 ttcatttgtc ttagctgcaa tcgttatcat tttgtctgga ctaagtttcg cagaatttgc
    34021 ttcgcgagtg ccagtgattg gtgggccata tgcctatctg tatgttgtat ttggtgaatt
    34081 tgctgcctgg ctgacagggt ggttgttgat cggggaattt ttactagcgg tttcctctgt
    34141 tgcttccgga tggtctggct atatgcaagg ttttttgaaa agtttagggg ccgaacttcc
    34201 acaagcatta actggcgggt acaatccgga aaatggtaca tacattgact tgattgcggt
    34261 gctcgtagtg atattcgtca cttacatcgt gtcgcttgaa gccaagaaag cattacgttt
    34321 gaataatgcc atggtatatg tcaaatttgg tatcatcgcg ttgtttatca ttgtaggaat
    34381 atttttcgtt aaacctgata actggcagcc attcatgcct tttggttttt ccggtgtgct
    34441 agatggtgca gctcttgtgt tttttgcttt cttgggattt gatgccgttg caatggcagc
    34501 cgaggaagtc aaaaacccgc aaaaagatgt gccaagagga atcattggtt cgatactgat
    34561 tgctactgtc ctttacatca tcgtgacgct gatcttgaca ggaatcgttc cgtatactga
    34621 actaggagtc aatgacccag tggcttttgc aatgaggtat gtaggacatg gaacagtggg
    34681 cgcggtgatc gctgtagggg caattttaac gctactgacg gtaacgatct cgatgatgta
    34741 ttcacttgct cgtttactgt ttgctgtcag caaggatggc ttacttccta agtttatgac
    34801 agaaatcgat caaaagcatc gtacaccgaa aaaagcgact tatgccgctg gtgtggcagc
    34861 tgtattcttt gccggatttt tcccattgaa tgtattagcg gaactaacga atatcatggc
    34921 gctcgcctat ttgatgcttg ttagtctagg cttactgaag ttgagaaaaa tgtttggcaa
    34981 accaaaagct ggagaattca aagtgccatt cgttccgcta ttgccaatcg tctccatctt
    35041 gacttgtatt gtattgatgc ttcgtctgca aactgtgaca tggatcgtgt tcggtatcgt
    35101 aatggttatt ggactgatca tttattttgg ctatggctat ggacacagca agatgaatga
    35161 gaaatagact ccaatggaga agttagaaga aagataagaa aaacgcccat caacagttgt
    35221 aataaactgt tgttgggcgt ttgttttagt aacaagcgaa aggtgatcta ttgggttaaa
    35281 tccaacagtt tttgtttcag atcttcttcc atgtgtccaa gctctacttc tgcatgacga
    35341 cgtttttctt ttccttcttt ttggatacgc aatgtctctt ggattgtttc gatcaaatca
    35401 ttttgagtgg tttgaagggt ctcgatatcc acgattccac gttcattttc tttcgctgtt
    35461 tcgatggctg agattttcag catttctgaa tttttcttca ataagtcgtt tgttgtttca
    35521 gagacttggc gttgagcagt tactgcatct ttttgacgaa gcaaggtcaa tgcgatcacg
    35581 acttggtttt tccacagcgg aatggctgta gcgatagatg cttggatctt ttcagccaag
    35641 gcctgatttg tgttttggat caaacggatt tgtggtgctt gctggatcgt gatctgtcta
    35701 gctaagcgaa gatcatgcgt acgtttatcc agacgatcta ggaattgcgt gtaatcattg
    35761 gcaatctgaa catccatctg atcgccagtt tcttctgctc ttttcatcgc ttctggaatg
    35821 atcgttgttt gaagttcttc cattttcaat tctccagcag cgatataaat attcagtgca
    35881 tcaaagtagt ctttgttttt ctggtaaagc tgttctaaca tcagattatc ttttagcaga
    35941 ccgtcttttt ctttatctaa tttcactgaa atcttgtcaa tttgtgcacc aatcttttga
    36001 tattttgctg tcacttcata gatcgattgt ttgaccttcc cgaagacacg ctggaagatg
    36061 ttcccttctc cggcacgcag ttcgtcagga ttggcttctt ggagacgata catcagttca
    36121 gttaaggaat ctcctacagg accaatatct tgtgcttgca catgattcaa catcgattgt
    36181 gagaattcac ttaattttgc ttgggcagcc gatccgtagc tgatgacaga ctgtgcatca
    36241 ttagcatcga tttttgctgc tagctgttta gcttgttctt ggcgttccgc cggtagtttg
    36301 tcaattaaac gagcagctgt ctgttgctct tggagctgat caatctccgc ttgttgtgaa
    36361 gtggtcagcg tatctgttgg agttgaaaac gggttgttca ataaatcttc aagtgtatcg
    36421 ttaactggtg taacatcttt tgtttcagtc ggtttatgat ccataaaaaa ttcctccttg
    36481 ttgaatctgt tctcgattct tacatgaatg tctctacttt agaaaaagta ctcgaaacag
    36541 ccagacatca tctgaatgtt ccgagtcttc ttttatgaac aaaagagtta atccttttgt
    36601 tctggttcat atttattatc acgctttaag ctctgtttcg caacagatat ctctacgtcg
    36661 atatcatcta gatcctcagc aacgaatttt tgataatctt gtgcgattaa agctgacagc
    36721 tggtcgatga tctgcgcgct ttcttctagt ttttcatagg tctgtttgtt tttgatctca
    36781 tggtcattga tctcattata cttatttgtc aaatcaacta gattcggcag atgcgtataa
    36841 agaaactgac ttgcttcatg cagtcggttt ggttctttca ccaattcttt gaataaagct
    36901 ttcgctgctt tgactggatc atggcggaga tcgattgctt taagtttggc tgtctgctgc
    36961 atattcattt gcaattgatt gatctcattt tttgtttgat tcattgtttg tcgaaaaaat
    37021 gaaatttcat tcgctgtcat accgcttttt tcatagtgag tttcaagttc gtcagtcagt
    37081 gcaggaattt cttcttgttt tccctttttc ctgcgcgaac caaagagtcc ccacaaaact
    37141 aaaactacac ctatcaataa aagtcctaga acaaaagaaa aactattgtt tcggacaaag
    37201 agaaatagca agaccaatgc tagaagccac ggccaatttc gttttatcat aataaaccct
    37261 ccatgtcatt tatcgttgag tattgaattc ttttcgttat tcgattacat acttatttta
    37321 gcatacggac tactagaaag agtatcggac taaagaagga ttttctatat ttagagaaaa
    37381 tctaaggttt atctatggta aactaataag gagtttttga gaaaaattga aaaatgaaaa
    37441 aaaagcagtt atgattacaa agaaagcagg agaagatatg ctgaacaatg agcaatttga
    37501 agaaaaaaca atcagtcgca aagaaatcta tagcggaaaa attattgatg ttgctgtaga
    37561 cgaagttcgt ttgccagatg gaggaacttc gaagagagaa ctggtatttc atcctggcgg
    37621 tgtcgggatc attgcttttg acgaacaaga tcgtctgctt cttgtcaaac aatttcgaaa
    37681 acctttagaa aaagtgattt tggagattcc agctggaaaa atcgatccag gagaaggaca
    37741 aaatcccgaa atgacagcag ctagagaatt agaagaagaa actggctatc gtgcgaagtc
    37801 gctgagccat cttacttcga tgtatctttc accaggtttt gcaaatgaag tccttcatat
    37861 ttatcatgca caaggggtag agaaggtcga gaatccttta gcacaagatg aagacgaagt
    37921 actggagttg tatcatctaa ctcttgaaga ggcgcaacaa gcgatgaaag atcagttgat
    37981 ttgtgatgca aagacgattt atgcgattca atactgggaa ctattgacca aaggaaagta
    38041 gagggatcgg cttatggcca aaggaccgct tattacgcga agcgaacttc gcaagcgaca
    38101 acaagcacaa gcaagcgagt cattaaaaaa acagcgaaaa gcagaaacag cttatcagca
    38161 agaagaaaaa aagattgcca gcttttatcg taaagaaagc aaaaagaata aaccaatcac
    38221 gaaaacaagg atcagcgaac gggaaaagac gaccaaatgg aactcttttt tgatgaaatc
    38281 tcttattatt gttatcctaa tgttatgtgt ggttttttta gcaatcgcat ttatatagaa
    38341 agaaggaatt aaaaagatga aaatcggtat tatcggcgca atggaagaag aagtaaaaat
    38401 tttgagagag aacctaagcg aaccattatc atgggaacgc gcaggcgctt tatttatttc
    38461 aggttcatta ggtaaccacg aagtgatcgt cgtacgttcc ggtataggaa aagtcttagc
    38521 atctattacc acaagtctgt tgatccaaca atacggcgtg aacatggtga tcaatacagg
    38581 ttcagctggc ggaatcggtg aaggcttaca agtaggtgac atcgttatat cagacaaagt
    38641 agcttatttt gatgcagatg caacaggatt tggctacaac ccaggacaat taccaggaat
    38701 gcctctatat tatgaagcaa gcacatattt gcgcagtgaa atggttaaag cagcaaaagc
    38761 aacgaatttg aacgcaaaag aaggattgat cgttacaggt gatacatttg tcgactcgcc
    38821 agataaaatc aaagaaatct taacgaattt ccctgaagca ttagcttgcg aaatggaagg
    38881 agccgctgtt ggacaaacag ctcgtcagtt caatatccca tttttgatcg tacgtgcaat
    38941 gagcgacaca gcagatcact cggcgacaca aagctttgac gaatttatcg aagacgcagg
    39001 caaacgatca gcagaaatgg tgatcgaatt tgtcaaacat ctcgtataag gaggactaag
    39061 atgaacgcat tgatctcgat tgactacaca tatgattttg ttgcagagga tggaaagctg
    39121 actactggga cagcaggaca agtaattgaa aaaaagctga ctgctcatac aaagaagttt
    39181 attgatcaaa aggattttgt cgtttttgcc attgatgcgc atgatccaaa agattccttt
    39241 catccggaga accgcttatt tcctccgcat aatgtgatag gaacgggtgg acgggaattg
    39301 tacggctctt taaaaagttt ataccaagac tatgagcaag aggaaaatgt ttattggata
    39361 gacaaacggc attattccgc ttttagtgga acagatctag acatccgttt gcgagaacgc
    39421 cagatcacag atatttattt gaccggcgta tgtacagata tctgtgtgtt gcatacagca
    39481 gtcgatgcgt ataatctagg atacaaactc catattttca aagattccgt ggcaagtttc
    39541 gatcccgttg gacatgaatg ggcattgaga cattttgagt ccacactagg cgcagaaatt
    39601 ttataaaaaa acaaagtgat ttgataaaat aaaaagcaca aaataataaa agaagagcat
    39661 aaaacaaacg actttgtttt atgctctttt ttatacgtta ttttaaaaaa acttattctt
    39721 tttccgttaa taaatctctt tattatcaac aacttaagtt atattttttc tttttataaa
    39781 atacacttat tataattttg ttttttattg acagtaaaaa taaattaggt aatactttaa
    39841 gtaaacgctt tctaatttgt tacgggagga atacacttgt taaaaaaacg tataaaatac
    39901 agtgcgctaa tgatgaatct ccttatgctc agtaccccgg ttttaatttc tgtcgttgaa
    39961 gttgctgcta acgaacaaca gtctgtgaac gaagaaaatg cacacgtgaa cattgaaggg
    40021 atgtcaacaa tggaggaagt accaagaact agtgaagata tggatacgga agaaggaaat
    40081 gatcctatga tgaaagaatc agaaaatgaa aagacaaaaa agcaatctga agaagcaaat
    40141 gaagagtgga aaggggttgt tttcggagaa agcacaagtg ctagtaggta tgccattgaa
    40201 ccattagaag acggcgtgcg gctctcttcc acgaataacg gcggaaaatt ccagtcaagc
    40261 ggaccagatg gaatgaccta ttattatcaa gcaatcccca aagacatcaa ctttaggatg
    40321 cgggcgacga tcgaaataga atcttggacc tatacgaatg cccaagaagg atttgcttta
    40381 atggtaagag acgcagtacc aaaagatcat ttgtttgggc aggcatttta ttcaaattca
    40441 tttgccatac taggcagtcg gatcgaatat gtctgggact cggatagaca agaagtggtc
    40501 aacacgagcg gcagcaaata tacgatgcga cttggattag ggacacgggc aatcacagga
    40561 atatcatctg aagatccgca agctgcgcca gctcctggga gtgtctcagt ggaaacaaca
    40621 cctttagaga cttcagcagg gttcttggaa aaagaaacag gttcttataa tatattcgga
    40681 aacggtcatg ggaatctgtt tccggccacg aactcgatta ctaaactgga cgtagagatg
    40741 aaaaaaacga atactggttt agaggcatat tattacgatc ctgaaacagg agaagaaatg
    40801 gcttctgaca tcatgtatga ctgggaaaaa ttatacgctt cagatgaatc ggttatttat
    40861 gcaggatttg ctgcagcaag gaatatgacg atcaaggtag aaggaatcga agttgcttac
    40921 tcggatcctg cgacagatcc tcctgggcaa gaaagactta ctcgcttgat tgatccgatt
    40981 tacactgtga cctctagtaa tcattcagga aaccaagacc atactatgtc ctttagagca
    41041 aatgctgacg gattattaac aatcaaaaat caagcaacag gagaggtact tgagaacgca
    41101 aaagacttgg caatcactgc aaatcgggaa tttgattatc agacaaaact gatggaagga
    41161 acgaacgaat ttactttcag ttttacacca gataaaaact atccgccaga agaatacgta
    41221 gagatggcta gttatgaaac aaaagagatt ctgcatacag ttgactaccg taaacctaac
    41281 tattcgacag tttatgtaac accggaaggg tcagatacag gaaacggaag cagacaaaat
    41341 ccgttatctc tgacgcaagc attgagatac gcatatgctg ggcagacaat cgtcctggct
    41401 cctggaactt attcctttga aagaggattg acgattccaa aaggagttaa cgggacaaga
    41461 gaaaacccga ttcaattgat tgcagagaaa aatccagaaa acaagcgacc tgtacttgat
    41521 tttaaaggaa ctggaaatgg gatgacactg tttagtcatt actgggtttt acgtgggttt
    41581 gacgttacaa atagtgccgc tatgcaaaaa ggattgcaga tttctggaaa ccataatttg
    41641 attgaagaga tccatgctta tcggaatgga aatacaggaa tccaaatcag tggtagctca
    41701 aatgatcctt tcgaagcatg gccagcgcat aacttagtca agaactgtac atcttttgaa
    41761 aatgccgatc caggatttga agatgccgat ggatttgcgg ccaaactgac aataggagaa
    41821 gggaatgtat ttgacggttg tatcgcttat cataatgcag atgatggttg ggatcttttt
    41881 gctaaaaatg aaacaggttc aatcgggaaa gtagtcatca aaaactcagt tgcttatcga
    41941 aacggttggg taccgggagt tgaaggagaa gggaacggta atggattcaa aatgggtgat
    42001 tcctctttat cgggccctca tgaattgatc aatagtttgt ctttcgaaaa tcttgcaaaa
    42061 ggaatcgatt ccaatagcgg aacagatatt atcgtcaata gcagtacaag ttttaataac
    42121 ggttcatata atgtggctct ttatacctct tcggcaggaa acacagactt ccatgcttct
    42181 ggtatcttat ctttccgaac agaaaatctt gagatgagag agcagatccg cccattgaat
    42241 caaaacgaag atcaaatcta tcactcgttg aactactatt ggaatgaacg agagaaacaa
    42301 tcagaaaata ctcttggaca taccgtatca aaagattgga tcgaatctct aaatacacat
    42361 tcgcaagaag ggcagcagcc tgttactcgc tatgcgaatg gaagcatcca tgtccatgga
    42421 ttgatgcaaa tcaaaccgga gaatcgtcaa acagaaaagg gaagagtaga tggtcttcca
    42481 ctatctgtag gtgctacttt tgacggagaa acctcaccgt cttcggagta tccagaatat
    42541 gcaatcgtac aagaaccaaa tcagacaaaa ccaaatgaac aaaataatcc gattattata
    42601 caagaagcaa atggtgtggc ggagaatgca gaaggaaata tcattgaact gaagcctttt
    42661 acagtttttg tgtcaacttt cacaccaaat caaggaacgc ctgtctttga agatatgcgt
    42721 tatttcccag aaaagatcca aatcgttgaa acacagtcaa gtgctcaatt ttctaatcat
    42781 accgctattt tttcagcacc ttcaaaagga gaatatacgc tagaagtcac ttatcgttcg
    42841 gaaatatttg atggggaaaa atggtctgct catacagaat ctgttaccca gcaaaaagcg
    42901 atcactgtgc gagaaactgc cgatgtgccc ccgggaaatg acaaaccaga aagagaaaat
    42961 ccaggaaatg aatcaccaaa tggaaaacca aatggaaaac caaatggaaa accttctcat
    43021 ccggatagga cagcaaaaga aagtgaaaaa aatggcactc aaggactccc aaaaacggga
    43081 gaatttaata acccgttgct agcattagct ggaggaattt tgttaatcgg tgtagttgtt
    43141 tatgtcatga aacagcgaaa aaaataagtg gaatttctcc ttttatgatg taaaacaatt
    43201 gactgaggaa agtaaaaata gaaggaaatg agaccaatag atgtctcact tccttctatc
    43261 tttttataga tgaggttctc cttgctgctt ttgattggct gttcttatta cttgatgcag
    43321 gacagctttt tcacaatctc tccactaaac ggtgttcaat cagctgaccc tcggtattag
    43381 ctcaacaaac ggcaaaatat gaagaactat ttttccgttt ttttctctaa tactcaggtc
    43441 aggacgctga tttcacaacc tctcgataaa cggtgttcaa aagccagttt ctcagtagta
    43501 agtcaaattt atgcaaaaat gtggaaagct attttcacaa aatttttctt actacttgaa
    43561 actaagcggc tttttcacaa cctcttacca gattcgcact cttttttctg gcgctagata
    43621 catagcgtct tgttccgtga taccaaatgt ttcatagaat tcgtcaaggt tttttggttg
    43681 cacgtttgct cggagtttag caggggcatg gacatcgatt tgcagtaaaa gttgttggta
    43741 ttcttttttt gcttttgtac gccaaatcgt tgcccaattg acaaaaaatt cctcgataga
    43801 aagatctgat tccgtttttg ctgcttccaa tgcacagctt agaccgcctg catcagcaat
    43861 attttccgaa acggttaatt ttccgtttac ttttccgtca gcaaaaggca gaccatcgaa
    43921 ttcttcgatc attgcttgtg ctttgttttg aaattgtgta agatcttctt ctgtccacca
    43981 gttgttcaag ttgccatatt cgtcaaataa agcgccgtta ttatcaaatg catgggaaat
    44041 ctcatgagcg ataacagctc cgattccacc ataattagca gagcttgatt gttctagact
    44101 gtaaaatggt gcttgaagga tcgctgccgg aaagacgatc acattccgaa atggatgata
    44161 ataagcattg accgtgtcag cactcatttc ccattctgaa cgatccactg gtttgttcca
    44221 tttgctgaaa cgatctttta atgtgagttt gctgaaaaca agagtatttg aaagcaaagt
    44281 accaccctga tctgcaggta ctgttttgaa ctggtcgaat aatgctggga tcttatcggg
    44341 gtagcctact tggataccta agttatttaa ttttatgacg gctttttctt ttgttgcatc
    44401 cccaagccag tcattttctt ctagacgttt tttataaacg gcgatcattt ttttcaccat
    44461 ttgttctacg tcttttttag cagcttcgcc aaaatatttt tttccgtagt aatcgccaac
    44521 tacttgatcg aattgtccag aggcaaggta atacgctgct tttttctgag gcattgcttc
    44581 gtctgttcca gacaatacgc gagaatagat tccgctgact tggcggaatt cttctgatag
    44641 ataaccacta agagaacgta ctgttttaat gatcatccag cttttgaata acggaaaatg
    44701 agcttctgtc aggatgtcat tcaaatgatc gaagtacact ggatcagtta cgatcacttt
    44761 atctggagtt gtcccaatca aacccgtgac aagttttttc aagtccagtt tatctgtgta
    44821 ttgaataaat gtatcaaaag attgcggatt atacattttg ctgtaatctg cgttttcttc
    44881 tgcacttttt acatgaggag caatcaattt atcaaattgc actgcttgtt ccgtgattgc
    44941 ttctgcctga cttttttctt tgccggcaag ctctaataac tgaacagcca tatcaaagaa
    45001 aacgcctatt agttgtgcac cgttgggatg gtctgatgca taatacgtct tatctggaag
    45061 gaataaagaa ggcggataag caaagaaggc gttcgtttgc gcattcttca tatctgcatc
    45121 tacatccaga ttaaatggca atggtaatgt atccaacagc cattctggaa attgctcatt
    45181 caattcgtcg aaagactgca atgattcaac tttttcgatt ataggttgaa gtggttgagc
    45241 atgcaactca tttcttcggt cataatcgtt tgccagttga taatatgcaa ggaaatgttt
    45301 cattttttct gaagacactt tttctggatg ggcaagcaga tcgtctgttt ctcccatcaa
    45361 aagttggtcg atcccgtcaa ctaaatcttg gaaaccgcct gtagctggtt tatctgcagg
    45421 gatttttgct gttttttgcc attcttcatt gactgcttca tagaaatctt gtttcaatcg
    45481 ttctttgttc attcatcgat cgctcctttt ttgtttcgtg tgcccattat cttacaaaat
    45541 gaaggaatta acaaatagaa cataaaaaat tgaaaattcg aacaatcaaa ctgatttgtt
    45601 tttttcaatc cttcacttat aatgaaaaaa aggaggcgat cccaactgaa tcaagtagtg
    45661 gataaacctt tatatttcaa agtagataaa aaaattaaaa aattagccag cactcagcag
    45721 ctgcagtcaa gaaaaagtaa attgcttttt ttagctctgg tttttgaaga tcaaagttat
    45781 gtgattatcg atcaatcagg acatccggta gaatattctc cagcaaaata tacttatcaa
    45841 gagggtcttt cttgtaaaaa atggaagctg atcaatgaag agccaatcga gttatctaga
    45901 tggatcaaca gaaaagaaga tattcccgtt ttgatcgaag aaaaaaggtc aggaaaggaa
    45961 ctcgcaaatt gctgggtggg attgccagaa gaacgttttt tgaggtataa gaaatgggct
    46021 accccctcag gctatctttg tggtacttac gcggcagcag ttctccttgc ctattatcaa
    46081 gactatcgta aggggtggat gcttccaaat gagattcgca agaaaaatac ggctgattcg
    46141 ttggttttga cgaaggcatt gcgtagccag atccaaccac taggacttcc tacgattcct
    46201 tttcaggtta gtacagggat ttctagtttt ttaaagaaga atggcaatca tgagcgtgca
    46261 cgagcaactc ttctaggttc atggcagcga gctacaaaac gtatacgtga aggcaaacct
    46321 gtgatgattg gtattttgaa agtacttggc agtacatatg gcaatcattg ggtgacagcg
    46381 tacgcttatt ttgaaactga aacaggagaa cgttattaca aagtacacga caactggggc
    46441 gattatcata aagtcattcc tgccagttgg agtaacggaa cagtttcact tccttaagaa
    46501 tttgctgaaa ttaacagaaa atcttggaaa aatatgttaa actatcgaag aatagagaag
    46561 ttttggggag gactacatga gtaataagta tcaggatgac acgttgaaga tttttagttt
    46621 gaatggcaac cgtccattag ctgaaaaaat cgcgaaagtg ttcggaacag aattaggtaa
    46681 aagcgtcgtg aagcaattta gtgatggcga gatttccatc aatatcgaag aaagtattcg
    46741 aggggatcat gtgtatatcg ttcaatcaac gaatgcacct gtcaatgact actatatgga
    46801 actactgatc atgatcgatg caatgaagcg agcaagtgcg aaaacgatca atgtcgtatt
    46861 gccttactat gggtatgcta ggcaagaccg cacggcgaaa cctcatgaac cgatcactgc
    46921 gaaattgatc gctaacttga tcgaagaagc aggggcaact cgagtactga ctttagatct
    46981 gcacacggtt caagtacaag gattctttga tattcctgta gataatttat ttacgatgcc
    47041 gttgtttgct cattattacc gtcaattagg tctgacggga gatgacatcg tagttgtttc
    47101 gccaaaaaac agcggtgttc agcgtgcacg tagtctttca gaatatttga acagcacatt
    47161 agccatcgta gatcatgcag atgatgcttc aactgagggt ggttatgtga tcggtgatgt
    47221 tcaaggaaag acatgtatca tggtagatga tatcttgaac acaggagcaa cgcttgcacg
    47281 agcagcaaat gtattaaaag aaaacggcgc aaaagaagta tatgcctgtg cgtcacatgg
    47341 attattgtcc gatcatgcga aaagtatttt agacaatgca ccaatcaaag atatttgtat
    47401 cactgattct gttttcacag aagaaaatcg tcatccagaa aacttaacaa tcgttacatg
    47461 ttcagaatta atgggagaag cggtcaaacg catccatgaa aatacaccga tgagtccgtt
    47521 attccgtctg gaagaaaaag aattcgaata aacaaaaaaa gagggaaaga agttgtgaca
    47581 caagtgagca gcttcaagga gctgcgacaa gacttttgtc acagctcctt ttttctatgc
    47641 ccatgaaacg tcctctagac aaaaatgagc tcttctttgg tttgttcgct attttatgct
    47701 agaatgtgcc tagcaataat ttggaaggga tgaatgaagt gaaaactatt tatctggatc
    47761 atgcggcaac tacccccatg catccacaag taattgaagc gatgacggca atcatgcaag
    47821 acacgtttgg aaatccttca agcatacatg gatttggtcg ccacgcgcat gaaaaattgg
    47881 aaacagcaag acaaatcatt gcagacagtc tgcaagcaaa acctcacgag atcatcttta
    47941 atagtggtgg aacagaaggg gataatacag ctatcttaga aacagcgttc tcgcgtcaaa
    48001 aagaaggcag acatctaatc actacagcta tcgaacatcc tgctgttctt aataccatga
    48061 aatatttaga gacaaagggg tttgacgtta catatctgcc tgtagatgaa aaagggaatc
    48121 tgtcgatcga agaggtcaaa aaagcgttac gagaagatac gatcttggtc tctgtgatgt
    48181 acgggaacaa tgaaatcgga aatttgatgc caatcaaaga aatcggtgaa cttttagcgg
    48241 atcacccagc ttatttccat acagatgcgg tacaagcgta cggaaaccaa acgatccatc
    48301 cagaagaatt aggaatcgat ttattaagta tctctgctca taaaatcaat gggccaaaag
    48361 gcgtcggttt cttatataaa cgagacggag taaatatccc tgcattgctt ttaggcgggg
    48421 agcaggaaga aaagcggcgt gcaggtacag aaaatttagc agggatctgg ggtatggcaa
    48481 aagcagttga actgctgtca tctgaagaac gtgaagcacg taacaacaaa tataaaggat
    48541 tccagcaatt gattcttgat acattagaag caaacgaaat cccttatcaa gtaaatggtg
    48601 atttaacgaa taaactccct catgtgttga atcttcgctt aattggcgaa gcaaatgatt
    48661 tgctactgat gaagcttgat cttaatgggg tcgctatttc tactggttca gcttgtacag
    48721 caggaaatat cgagccttca cacgtattag aagcaatgta tggagaagat acaccgatac
    48781 taaaagaatc catccgtatc agctttggtt tgggaaatac cgaagacgac atccagtatt
    48841 tccttgatca attagttcgt gctgtcaaaa aataactagt gaagtcattc ttatatgaac
    48901 agatgtctga gagaacgcct tcatttttta gggaacttaa ctgaaaaacc tagtaaaaat
    48961 caggataaac ttttataata aagagaaact aattttatcg aggtgaaaat catggcattt
    49021 gaaacaacag caacggtact gggcgcacca attagctatc gtttgcatcc tgatgcaaaa
    49081 agatatacat tgcgcgataa tggatttaca gaaacaaacg gaggcaatta tcaattgatc
    49141 cgaccattag atgccacgcc gcaaagcaaa gaaggattca aattaaaaat cactgtatca
    49201 aaagatattc aaacattgaa aatgtcgatc actacagcaa atggattgaa agcagtcaat
    49261 attttcaaag atccaaaaca gaaaatgagc caagataaat tttattttct gatggatggg
    49321 atgattagcc gtgggttatt cgaaaaagtc gaatgatctg tggatataaa aagacaacta
    49381 gttttgaaac ggcctattgt tagatgacta actttgtaag gacgacgcaa attagttgtc
    49441 ttttttattt ttaaatttaa cacatgttgt tatttttaat attttgctga tttattgttt
    49501 ctaagtaaag aaatttaaat tgaaacgatt gttatttagg gaaaaaggta ttttttgaaa
    49561 aaagaatccc gtataatgat tgttgtgcaa acgctataca aaatgaaaaa gaaaagaggg
    49621 atgtttatgg aaaatgaaca gtcggtcgtt ttaacgaatt ggaagagaaa ttatttgttc
    49681 tttttatcgg gacagttttt gtcaggaatc actagtatgg tcgtccaata tgcgatcatc
    49741 tggtatttga caagagaaac cggttcggcg acaattttga gttttgctac tttactagga
    49801 atgattccca tggttttact aagcccattt gtaggaccgc tagtggatcg ctgggataaa
    49861 aaagctcttt tgattgtcac ggatattatt gtagcgattt tcgcgcttat tttagcagta
    49921 gtcggaacga tttcagaatc cttcccgatt tggctagttt ttgtgtcttt gtttatgcgt
    49981 tcggtcgcac aaacattcca aatgccaacg atccagtcga ttatgccgac aatcgttcca
    50041 tcttctcaca taacaaggac gaatggacag ttaggaatgg tccagtcagc gaatttcatc
    50101 attgcgccag ctctaggtgc ggctttgttt tcagtcgttc ctgtcaatta ccttatttta
    50161 ttagatgtat tgggggcagt ttttggtgtc ggcttattga tttttgtgaa gatcccaaaa
    50221 gtttctcctg aaatattgga agttccgctt actattttta aagatgcaaa atttgggctg
    50281 cagcaattga tggataacaa agggttatgg tacataacga tcaatggtgc atttgtgatg
    50341 ctgttgttca tgccagcaat cagtctgtat ccattgatga cgctagatta ctttggtggt
    50401 tccgttggac aggcgggagc agtggaagta gtctacgcag tcggaatgct cttaggcggt
    50461 gcactgatca gttttatagg aacatggaaa gaccgaatga aacctattat tatagcctac
    50521 atcattatgg gcctgacgat cggtgcaagc ggattggttc caaacgatag tcaagggttc
    50581 ttgtactttc ttatcttgaa tgcaggagca ggttgtgcaa cgccatattt caatacactg
    50641 ctgatggcaa tgatccagca gagttatgaa tcgaatgttt taggtcgtgt cttagggaac
    50701 ttcaactctt tgatgaacct ggcaggtcca attggattat tatttgcagg accattagct
    50761 gatcgtttag gagtagaaaa aatgttcttg ttttctggaa tcgggatttt attatgcgga
    50821 atcgttttat ttttaacgtc agctgctcga aattatgata aagaattaca gaaaaaattg
    50881 gtaaaagaac accatgagca aaaagacgaa tagtatggaa tggagttgtg acagaagtct
    50941 tgttacaact ccatttctga tcctaatgtt cctgtggcaa taagcctact caaatgaaaa
    51001 atatgagtaa ttatctttat ttgtttaata cttgatatag ggcagttttt tcacgaccta
    51061 tcgtacttcc tctttgcttc atagatttct ttgatttgtt gctcagataa cggagtgcca
    51121 aatggtagtt tttcctttaa gagttctctt tccggtgcgt ctacgcctac attgacatcg
    51181 ttctcgatag gtacgctgta atgatggata tgtccatgaa gattgcggat agtgtcgtta
    51241 ggcccgagca acatcggata atgagtcaag taatattgtt gatggtcgaa tttaacgatg
    51301 gcacctacat cataaaaata aaatttggga cttccgtcag taagcctagg atcatttttt
    51361 tctaaataac ggaaaaaagc acgactgtca tggttccctt tgatcaagtg gattgttcct
    51421 tgcagttgag tgatcagttc caaaatttct gcatttgctt tttcatattg cggatgcata
    51481 gcaaggtcgc ctagatgata aacatggtcg gtttctttta ttactgcatt ccagctagtg
    51541 atcaactgtt ggttcatttc atccacattt gcaaagagcc gcggagcaaa gtcgtttttt
    51601 cctaataagc gttcatggaa aaagtgcata tcactggtaa agtaattcat gtatctcttg
    51661 cctccctttt ttcttagagt aaacaaaatc acttatctga gcaactcata acatctaaaa
    51721 agaaaaggtt gtaaatgaga cgtgcagctt taagcgataa gaagcaattt tgaaaaatag
    51781 tttttcacaa tttacaaaat tattccttat tgccgaaagg ctggcccttt ttatgagtat
    51841 gccaattttt tatatcgaat gctcaaaaga tgagtgattt tttggttgac tatcatgttt
    51901 gtgtactgaa taggtccagt agaacagtat ttttacgact tgataattaa gggatgaaat
    51961 tttcagaaat atgacgtata atgtaaaata ctgaaaagtt gcgaccttca actcgtagat
    52021 gtttcagaat ctaattgaaa tgatggtgat atcatgacag acaacagcaa aacacgcgtt
    52081 gtcgtaggga tgagcggcgg tgtcgactca tctgtaacag cacttttgtt aaaggaacaa
    52141 ggatacgacg tgatcggaat attcatgaaa aattgggatg acacggacga aaacggtgta
    52201 tgcacggcca cggaagatta taaggatgta gcgaaagtag ctgctcaaat cgggattcct
    52261 tattactctg tgaattttga aaaagaatat tgggatcgtg tatttgaata tttcctagcc
    52321 gaataccgcg caggacgtac acctaaccca gacgtgatgt gcaacaaaga aatcaaattc
    52381 aaagcattct tggattatgc aatggatctt ggcgccgatt atgtagctac tggacattat
    52441 gcgcaagtca ctcgcgatga aaacggcgtg gtccacatgc ttcgtggagt agacaataat
    52501 aaagatcaaa cttacttcct tagccaatta tcacaagaac agctttcaaa aacgatgttc
    52561 cctctaggcg gcatggaaaa atcagaagta cgggcaattg ctgaacgcgc aggccttgcg
    52621 actgctaaga aaaaagattc aacgggaatc tgctttattg gtgaaaagaa cttcaaacaa
    52681 tttttgagca actatctgcc agcaaaaaaa ggagatatgg tcactcttga tggtgaagtc
    52741 aaaggacaac atgctggctt gatgtattat acgattggtc aacgtcaagg actagggatc
    52801 ggtggcggag gagattcgca agaaccctgg tttgttgtag gaaaagatct agcgacaaac
    52861 acattatatg tggggcaagg gttccatcat cctgcattgt atgccacaag cttggatgca
    52921 agtgaaatcc actttacgac gaatgaacca atgccaaaag aattcaagtg tacagcgaaa
    52981 ttccgttatc gtcagcaaga cgttcctgtg acagttcgct tattggatga taatcgtgca
    53041 gaagtcgtat tcgacgaacc tgtacgtgca atcactcctg gacaagcagt tgtattttat
    53101 gatggaatgg aatgtctggg tggtggtttg atcgaccacg catatcaaga aacaaaagtt
    53161 ttacaatacg tttaagcgat attaaatgaa tcaaaacagc tatggctaac aaaagaaaca
    53221 ccttttcttt tggatagcat agctgttttt ttgcaataaa attaattttt attcatttta
    53281 tacttgaaat acttgtgtaa aaagttcata atatccaata atatgaataa agttgctttt
    53341 tgttaagcaa gagcagttgc aaaatagaag ggaatctttt gcaagtgatt tgttcaattt
    53401 tataagtgag ggtgatggaa atggaaaaga aatcgacggg tattagcaaa tggggactgg
    53461 ttgctctggt tgtcagttcg tcaatcggaa gcggtgtgtt tgggatcaca agtgatctgg
    53521 ctagttctgc agctccaggg ccagcgatcc tttcatggat aatcgttggg attggtattt
    53581 tagctttggt attatcgctg aatcatttag gagaaaaacg tccagatcta gatggtggta
    53641 ttttcggtta cgcggaagct tcatttggta aattaggtgg cttcatcagt ggttggggtt
    53701 actggttgtc tgcgtggctg ggaaatgttg cctttgcaac gatgctgatg agcgccatgg
    53761 gagaattttt cccgatattc aaaggtggac aaaatgttcc ttctatttta tttgcaagta
    53821 tttttatttg gggtctgact ttattagtaa acaatggagt tgaaggagcg agcgtcatca
    53881 atacaatcgt gacgatctgt aaattagtgc cattattcct atttttaata tttgtattta
    53941 tcgcatttaa agtgaatata ttcactgctg atttttgggg taacgtatct gataatctag
    54001 tgaatggaac agggcagcaa ggaacgatct ggttgcagat taaaggttgt ttgatggtta
    54061 tgatgtgggt ctttgtaggg atcgaaggcg caagtgtttt agccaaccgc gcgaagaaac
    54121 gttcagaagc ccagcaagca tcgatcattg gtctgctttg tttattgttt atctatatcc
    54181 ttgcttcgat cttgccatac ggcgtcttat ctcaagaaga gttagcaact atttcacaac
    54241 ctgctatggc aaatatttta aaaggaatcg tgggaaattg gggagcagcg ctgatcaata
    54301 tcggcttgat tatttcgatc attggttctt ggttgtcttg gacgatgctc ccagcagaaa
    54361 caacgatgtt gatggctcga gacggtctgt tgccgaaagg ttggggaaaa acgaataaaa
    54421 aaaatgcccc aacttattcg ttagttgtta ctgcaatctt gactaatcta ttcttattga
    54481 ctttcttagt tactgattat gcctatcaat ttgcctattc tttatgtaca gcggcaattt
    54541 tgatttgtta tctacttgtc gggatctatc aagtccagtt ttctttaaaa gaaggaatca
    54601 aaaaacaagt agtgatcggt gggattgctg tagtttttga attgatgggc atcattttag
    54661 caggattttc ttatgtcctt ttatgtagta ttgcctatct tcctggtttt tgcttctact
    54721 ggatcgcttg tcgtgaaacc aaacatcaaa ttacgggaaa agaaaaagta atgattgggc
    54781 tgatttgtgt ggccgcactg ctttcaatcg ggttgcttgc tgtaggctgg atcaagatat
    54841 aagggggaaa gaaacatgaa aatcgcaaat ttcggtgtag aagaatggct aaataaatgg
    54901 gaaaagaaag cggtatatga tattgcacaa agctcgatcg aagcattgac attagacgaa
    54961 ctcgttggct tagatgggac tagcgtaagt gaatttttcg aaaaacgcaa aaacgaacca
    55021 ttggactatg gctggatcga aggatcagat gttttcaaac aagaagtcgc ttctctttat
    55081 caaaccgtca atccggaaaa catcttacaa acgaatggag cgactggtgc taatctttta
    55141 gctctatacg cgttagtgga agcaggagac catgttgttt cgatgcttcc tacttatcag
    55201 caattatatg acatccccaa atctttaggt gccgctgttg actttgttca tttgaaggaa
    55261 gaagaagatt ggcagtttga tttagaacag ctagaagcct tagtcaaacc tgaaacaaaa
    55321 atcatctgtt tgaatagtgc aaacaatcct acaggcacat tgctagatcg gaaaacttta
    55381 gaaaaaatcg cagaaattgc tcgtacagta gatgcatatg tattgataga tgaagtatat
    55441 gcgcctttaa cggataaagg tgaattcttg tcgatcgtag atgtctatga aaaaggtata
    55501 gcaaccaatt ccctatccaa aacctactcc attccaggta ttcgtattgg ctggacagct
    55561 actggacctg agttggcaga agtttttcga aagtatcgag actacacgat gatttgcggc
    55621 ggagtcctgt cagatgatct tgctgtacat gcattgaaga ataaagaaaa aatattggag
    55681 cgaaacaaaa agatcattac agagaacctt gtgattttaa aacaatgggt agccaatgaa
    55741 ccgaaagttg aacttgtcgc tcccaattac gtctctactt ctttcattaa attagccatc
    55801 gaagaagatg accagacatt ttgtatcaat ttattagaag aaacaggagt actattagta
    55861 ccaggaagtg cctttgattt accgaagcat gcccgactag gttactgttg taaaaaagaa
    55921 accttggaaa agggattatt cctcttatct gagttcttga aaaaacaggc ctaaacaaaa
    55981 acactgcaag gacagtctgt gacaactgtt caagcagtgt ttttcattta cgcttattgt
    56041 ctatgagaag gagagtgccc tgaagatatg gagactcctg aagctttttc ttctgcagtt
    56101 tcttgctgat ggatttcttg tgtattgtgt cgtacaagca agaagttgac caaaacaaga
    56161 agagaagtcg aaagaaaaac gccacgataa ccaaatgcac tggaaacact ggagccgatc
    56221 ataggcccta ctacgttacc agttgcttgg aaagattggt tataactgaa gatccgtcca
    56281 gcagcttgat gaggcgaata ttttgtgatc aatgcttgga cagcagggag cagacaagca
    56341 tcagagatac caatcaaaaa acgtaaggca gctaattgcc aaacattcgt gacgaatgac
    56401 attgggatat aaaccagaat cgcaaaaccc aaaccaatcg caagtattct ttcactcccg
    56461 atcttgtcac ctaagcgacc aaatcttgga gcggctatca aagtggcaat cccaggtatc
    56521 gaagcgatga ttccgctgat caacgtaaca ttcccatgtc catgcagcaa ttggcgaatg
    56581 tacagactga tgattggact aatggaattg ttggatgctt ggatgatcat cgttgtgacg
    56641 aacataccga tgacgacgtg tggatatttc aagtctttga aaatctgttt ggcagaaacc
    56701 atgttttctt ttttcactgg gacaaatttt tcatggacga aaaacagact caacaagaag
    56761 acgaaaaata agatgatccc tgtaatgaaa aaggtagggc gatagccaaa cgctgaagca
    56821 gagatcccgc caagaagcgg tccaagtaat gttcctgtaa cagaaccagt tgctaaggtt
    56881 ccaagaactt gaccactttt ttcttttggc gtcccagttg cgacaagggc agtggcatta
    56941 ctgatataac cagaaaaaat cccttgaagc agacgcaatg cgactaattg atacacacta
    57001 gtcacgcaac ccatcaaaga aatgacgatt gccattccta atgaagcacg caacagcatc
    57061 aattttcttc ctttttggtc ggctaatttt ccccaccaag gagagatcag cgtagtcacc
    57121 aagaaagtag atgaaaaagt caatccgctc caaaagttca attgtgacgt actataatta
    57181 cctaacgtat ctatgtaaag tgacataaaa ggcatgacta aactaaatcc gataccagcc
    57241 ataaatgttc caaaccataa gacaaacaag ttttgttccc aagtttctct tttcctaaat
    57301 aatttttcct ttattcttgc agccaattag actccttctt tctgaaaatt ttcatctaca
    57361 gatctttatt ataaactaca atatgtagtt tatcaatgaa agtctctttt ttctctttct
    57421 ttttcgtggt aaactgaaag agtgaaggat ttattttatg agaggaaaca tggaaatgaa
    57481 aaaaagaaat ctgtctcaag agaaaatcat cgactgcttt cgagaactag cagaagagat
    57541 ggatgttcag caaataacct ttcagcattt agccaaacgc ttggatatca aggctccctc
    57601 gctgtataac catttcaaaa atattcgtga tgtcaaaaca gcgctaacag cgaaacttct
    57661 gcaggaactt aatgaccagc tgcgtcgggc tcttgtagga aaaagtggtc aggaagcact
    57721 gcagatctat gcagaaactt atcgatcctt tgctttttca aatcaagcag tgtatgagtt
    57781 actgatcagt gtaccgcata ccaatgaagc tgttttatta gatggaatcc atgaaacgaa
    57841 tcagatcatt ttgcagatat ttgaggcttt tcaattaacg aaagaagaaa aagttcatcg
    57901 aagcagggaa cttcgtagta tgatccacgg ttatctttcc ttacgttttt taggatactt
    57961 tacaaaagaa ccaacaatcg atccagaaga cagctatttt tggatgatca atgactttat
    58021 cgctactttg ccttaaacaa tcagattcat ttgtaacaat tttaagatgt tcattaaatg
    58081 acccttttat aagagaaaat tcttgcaact ttcttgaaaa gtgactaaga tgagtctaga
    58141 aaagctgaaa gaaggagcac gagtatgtat caagtaatta ccatgttcgg ggacaatgag
    58201 ccttggtggt tttttgaaga ctgggaagaa gatattgaag cagaagaaac attcgagtct
    58261 ttcgaagaag cacgacaagc gtacgaaaaa caatggaacg aaatccatca aaattatgaa
    58321 tatatcaatg caaaaagtaa ctttctcagc gccttttgga atgacggaga tgagcgctgg
    58381 tgtgaagagt gtgacgatga tttacagcaa tacaaaggac ttgcgttgtt gaaaaatcat
    58441 cagcccatca cagtagaaag cggaaaggaa ttttatgaaa caactaattc tagcggaaaa
    58501 accaagcgtt gcgaaagacc taagcaaggt gcttggtgct aatcaaaagc acaaaaatta
    58561 ttatgaagga cccaaggtga tcgttacttg ggcccttggt catttattag gattgaaaat
    58621 gccggaagat ctgaataagg aatggcagag ctggcaaatg gacacgttgc caatgatccc
    58681 taaaaaacta ggaatcaaac cacttcctaa aacaggacat caattaaaag caatcaagca
    58741 gctagctcag cgaaaagatg tctcagaagc agtcattgcg acagatgccg gaagagaagg
    58801 ggaacttgtt gctcgctgga tcttagagta tgtgcatttc aataaaccag tgaagcggtt
    58861 atggatctct tctcaaacag ataaagcaat caaaactgga ttcaagcaac taagacctgc
    58921 gaaagaatat gatgcattgt atgaatctgc tcttgcccgg gcaaaagcgg actggctggt
    58981 aggattgaat gtgaccagag ccttaactgt gaagtacgcg gataatttat cagcaggccg
    59041 tgtgcagaca ccgacactag cattagtgag agaccaagaa aagaaaatcg agcagttccg
    59101 tccacaaacg tatttcacga tcacgttgca agctggaaaa gaacaagcca aaatgcttca
    59161 aaaaaatcaa tttgctttaa aaacacaaga agaagcacaa aaacttgttc aattgatcag
    59221 tacaagcaaa ggaactgtca cagaagtcca agaaaaatta aaaacggaat ctgcgccatt
    59281 gccttatgat ttaacagaga tccaaagaga agccaatcaa cgctatggct attctgcaaa
    59341 gaaaacatta aatcttgtac aaagtttgta tgagacccat aagatcgtta cttatccgcg
    59401 tacagacagc aaatatctga caaatgacat gaaaagtacg atgaaagaac gattgcaagc
    59461 agtcagcgac tttgctcctg aggtcaagca gtatttgaaa aacggagcca tcgtccaaca
    59521 gacaaaagta ttccaagaca gtaaagtgac cgatcaccat gcacttttgc caactgaaaa
    59581 cagagcacgt tatgaaaaat taagtaatga agagcaaaaa atctatcaaa tgattgtctc
    59641 tcgtttttta ggactgtttg ctcaacccca taaagtcagc caaacaaaag ttacggttga
    59701 atttggtaaa gaacgattca tttttcggca aaatcgtgtc gtccaagcag gatggaaagg
    59761 cgaaactgaa actgagacgg aaacagtcaa atgggaaaaa ggaatgagaa tcaatcccga
    59821 tttcgccatc aaaaaagaac tatctgcacc gcctaaacca ttgtcagaag caagcttgct
    59881 tggtcaaatg gaaaaataca gtctgggaac cccagctacg cgtgcagaga ttatcgagaa
    59941 actaatcaaa tctgaactga tggaacgtat ccctcaagga ctgcaagtat ctcctaaagg
    60001 taagcaatta ttagtattgg taaatccctc tttagtaaca ccagatttga cagaaagctg
    60061 ggaaaaagac cttgaagcta ttgctgcagg aaagaaacaa gcaggaacct tcttgaatgg
    60121 aatcgaaaaa gaaacaaaac gcttggtgaa tgagatcaaa tcaagcaaac aagaatatca
    60181 agatttctcg attacccaaa agaaatgccc agaatgtggg gccaatctgc gcgagaaaaa
    60241 cacacgtgac ggcaaaatct atgtctgcac caattcagat tgcaactacc gcagaagaaa
    60301 agatccaaaa gtctctaatc atcgatgccc gcaatgtcac cggaaaatgg aaatcatcga
    60361 aggtaaaaac ggtgcttatt tccgttgtaa atacgatgga acgacagaaa aaatgcttga
    60421 taaaaaagag cagaagaaga aaatgaccaa acatgaagaa cgacgcttgc tgaaaaaata
    60481 tgcacaagca gaagaaccag aagaaagccc attagcagca gcactaaaag cggcaatgaa
    60541 gaaataataa gatatgaaag aggttgtgac agaagtggtc agcttcaaga aataagaagg
    60601 aatttacgaa aattgcttct caaatttttg tgaaatttcg gcttatttcc gaagaagcta
    60661 cttctggaac accatttatt cggaaaaaag gactgtgaca agacttttgt cacagtcctt
    60721 tttcatttaa aaaaatgttt acttcatttg acgtatatta ttggtgaggc ttcaattcat
    60781 ttggcttcac tttttctgtt tctcttatga tataaacagg acgctgtttc gtttctaaga
    60841 agattttccc gatatatttc ccgatgattc caagacataa caattggatt ccaccaatga
    60901 acaggaagat cgagaccatg gaaggccatc ctgatgtagg atcaccaaac aacaatgccc
    60961 gcaaaataat gaacaaaatt gcaataccag aaccgacaca agacaaagcg ccgataaatg
    61021 aagcaatcgt taacggtgca tccgagaagt tcacgatacc atcaatcgag tagttgaata
    61081 atttccagaa ggaccaagat gtttcgccag ccacacgttc gcggttttca taagaaatat
    61141 attctgtttt aaacccgacc cagctaaata atccttttga aaatcggttg tattctgtta
    61201 attctaggac ggcatccacc atttgacgag tcatcaagcg gaaatcacga gcgccatcga
    61261 ccatttctgt atcgctgatt ttattgatca actggtagaa ttttttcgca aagaaactgc
    61321 gtatcgcagg ctcgccttca cgagtcgaac gccgggtgcc gacacaatcg atatcagaag
    61381 tagtgatccg gttgatcatc tcaggaagca attcgggcgg atcttgcaga tcaacatcca
    61441 tcacggtcac taaatctcct gtagaagctt gcaatccagc gtatagagcc gcttctttcc
    61501 caaaatttct ggaaaatgag acaaagcgga cataaggata agctgaggct agcttcttga
    61561 ttgctgctaa cgtaccgtct tttgatccgt cgtcaataaa caaatattcg aactcatggg
    61621 cacctttgaa tttttcaacc tcatcaaaaa aaagaggaac agttttttct tcattaaaac
    61681 atgggacaac aattgatact ttcatcgttt ctatcctttc aatcgtatgt ttatatatgg
    61741 tttacattca aaatttaata aaccttaaat aacaccttta aaatttgatt ttacgtaaaa
    61801 gaacaggtat tctttttgta aactaacgta tttagtttac catgtttcct cggtttatca
    61861 aacttttaag aacaattttt attagttggc aagtagtttt ggatagagaa aaaggaggaa
    61921 gttccagtct attgactaga agcaaacaaa atgaaaatac acacacctat cggcttttta
    61981 tggttagatg cagatgaatc cggattgact gctgtatctt ttcagccaat ttcagaaagc
    62041 gaatcagcga atcagcaaat tttaacgcgc acacaagaac agtttgaaga atattttgcg
    62101 ggaaaaagaa aagaatttga tgttccttta tctataaaga gaggtacgcc ttttcagcaa
    62161 aatgtctgga aagctttgtc gaccattcct tatggagaaa tccgaacgta taaagaagta
    62221 gccgttgctg ttgatagtcc gaaagctgtg cgagcgattg ggcaggcaaa tcgaaccaat
    62281 ccattgccaa tcgttattcc ttgtcatcga gtgatcgggc aaaatggaaa actgacagga
    62341 tatatgggaa acgcaataga tggggttgaa atcaaacgcc aattgttgtt gttagaagga
    62401 tatctgcaaa attaaaaaca gttgtgattc ggacattgtt ccatgcgaga atcacaactg
    62461 ttttttcatg ttcattctaa actttgatca gccaaataaa tagtaaagcc atcactgttt
    62521 ggagaagccc gacagctaat ccataaaata agaagcgtgt accttctttc atgaattttg
    62581 caaagtctaa acgcagacca attgccgcta aagcagtgat ctcaaaccag ctgctgataa
    62641 aatgtgccga ttggtcaata actacaggta aagaaaacaa gctgttgacc aaacaaaaga
    62701 tcacaaaccc taatacatac caaggaagtg gtaattttcg ttttttctgc gtatcagttg
    62761 gcgtttcaaa cagagctggt tgtttcttgt gcatgaattt ttcaaacaga tagacaacaa
    62821 caacgagcat cataatacgt agaatcttaa atagcatggc gaattcgaca acagaattgt
    62881 caagtaagct tgccccagcg actacttgac caacagattg gagtgtgcca cccaaaagtg
    62941 cacttttttc aatgagattt ccaccaaaca actgtaatcc aagaaaaggg agagtcaaca
    63001 tcatcacagt acccagtaga ttgactagtg tgatgatctg tcctttttct tcctctttcg
    63061 catggatgga aggggcgatc gaagcaatag cagaagaacc acaaacagcg tttcctccag
    63121 ccatcatcaa agaagaagta tcgctgaatt gcagtttttt accaatcaag taagcaccga
    63181 tgatagtgac tgacatttgc agtaacacaa aaacaattcc ttttatacca atttgagcaa
    63241 tcgtttgagc tgtgacagtt gcacctagta aaaaaacaga gaattctaat agtttgcttt
    63301 cagcaaattt tgtgccgatt gctagaacag gctgtttaaa aaaagtattt cctaataaaa
    63361 tacccaataa aatagcaata gtcgctccac ctaactgtgg cagataaata gcaagaagcc
    63421 tgctgaaggc agcgatggca aaagaaagca gtaaaccggg taagatttcg cggaccgctg
    63481 aatcctttac agattttatt ggatgtgaca atgatttcat ttgatcggtt cctttcgtca
    63541 ataaatacta aaagcatact cgaacatagt agcactaaac cagtattttg acaaaagaac
    63601 aagaggtcgt gacaaaagtc ttgtcacgac ctcttgtttc gaataaacgg tgttcaaaag
    63661 ccagtttctc ggtattaagc caaatttatg caaaaatgtg gaaagccatt ttcacaaaat
    63721 ttttcttaat actcgaaact aagcggcttt ttcacgacct cttggtaaac ggtgttccag
    63781 aagtagcttc ttcggaaata agccgaaatt tcacaaaaat ttgagaagca attttcgtaa
    63841 attccttctt atttcttgaa gctgaccact tcttttacga cctcttggta aacggtgttc
    63901 aaaagcttgc atctgcggta ataagcccaa ccagtacaaa aacatgaaca gctgtttttg
    63961 tttggccgtt cttattactt gatgcagaac agctttttca caacctattg aatcgattat
    64021 taagcgattt ttttagaaac aaattttcca tgtttgctat gttctttaat taagaaacgt
    64081 acgtaatgag caagaacgta gaagacaact acacttgcaa acagacattc cgcaactttt
    64141 aagaaatcca atacgctact atagatacct aaactgttga agtaatgaac agtagtaaat
    64201 atagctgttg cagagataac aagcgggaat gtaaaggctg catagcttgg ataaaaacga
    64261 agcttgaaca aacgtggaag catagacagc acaacgaaat acaatacttg agataaagcg
    64321 aacaatgcta cgacaagata aaaattaggt tcagcaaagt ttttaagata acctgttagg
    64381 caaagagaac caggtgctgc aacgatcgta atcagcggac gtgtcggatg agccatattt
    64441 cttacgaaaa agacacgttt gatgatgatc ggcaataaga acgcatagca gatcaatgaa
    64501 atccaaaaga aaatttttcc aataagcggg aagaagttcc cggcagttac agtgatgacc
    64561 ccaaatccaa cgtaaatgat aaaccagctt ggataaattg cttcaattga aagatcagct
    64621 ttgataacat ggtgataatt gaaataaaag acaaggatca cttggaagat aacagcgcac
    64681 agccaaatga atttgacaat tggtgcaata ctttcatatg aaacaaaata agtacaaata
    64741 accatgagtg acatcgtaaa agttggtgaa acggaggcga tgattggatc atgcaacgtt
    64801 tgtttcgtgt gttcgaataa gataaacaat ttaacaaaaa tgaatatcat aagaatcata
    64861 gagataccgc cagttagatt gcctaaagca acatggtgat agtctttaaa cagatttcca
    64921 agggaagcta acccaaggat caacccgcag atcgggatcg gaataatttt caaaaagttc
    64981 ttcatatata atattctcct ttttatttaa tagattttag taccaagatg aacgaataca
    65041 ttgtaaaatg aataggaatg tatgattacg agcaagcaga cagctgattg tcttcatcta
    65101 agttactagt tggatcagca actgttttgt tgtacatttc tattatagat ggttttttgt
    65161 atatttaaat caaatagttt ttatagtaat tatcataaaa agttatggaa gtggtgccat
    65221 gtttaagtta ttaacgactt ttcgagcagt atatgaaaca agaaattttt ccagagcagc
    65281 agaagtactg tttttatctc aaccagcagt ctcgaatcaa atcaaacagt tggagcggga
    65341 attgaatatc gatctttttc aacgtaacgg aagaaaagag atgcttccaa ctaagcaagc
    65401 cgacttatta tatgaacgga cactggtttt gttagaagaa tgggaagaaa ctcagcaaaa
    65461 attgctcaat gaacaaaatg aagaagaagt atgtcggatc gttgcttccc acacctttgc
    65521 tgtctatctt ttgcctcagt tgatgaaaca tctgatcaaa aggtttccta aagtgcattt
    65581 tgagatcgaa atcgcgaatt ctcatgaatc attagaacaa gtagcgaaac atgaatccga
    65641 ttttggtttt atcgaaaagc cattagagac ttccggcgta caaagatact ctttgatgga
    65701 agaccagcta gtcatcgctg gggacccaaa aagcaaattg tggcttgtaa gagaagcaaa
    65761 ctctggtgtt tttcattata cgcagcgtta ttttgaagag atgaatatcc aagataagaa
    65821 gatgatcgtg aaaagtaacg atgtaattgt tgcgttgctg aaggaaggaa tcggtcgctc
    65881 gattttgtct aagcgctctg ttccagaaaa tgtgccaatg actccgttga atttccatcg
    65941 atatttttat ttcatccaac gaaccaatct ggtttctgat cagctgctag agattgccga
    66001 agagatcctt cgatacaatg aaagcacaga aacttctcac agcgaggaga atctcagctg
    66061 gtagataatt gcatgtatca aaaaaagttc tatgatacac taaagataag cagtaggctt
    66121 ttgtactgca tttgctcaag caactgcaca aacggaaagt taatttttcc caaatgtcta
    66181 tggaaagact ttccattatc taactggacc gctataataa tcagcagtat ggtttttaag
    66241 aaaagggatg aaacatggaa aaaaaattaa aagcttcgaa cgataatcgt attgattatg
    66301 gcgtgatttt accagtcttt ctgttatgtt tgattggtct gctctcatta tatgtagcac
    66361 ttagccatga tccgaacaat ccagcagtct tgaaaggcgt agggatgcaa gttgtctggt
    66421 atttagttgg agcggcagca atcgttgtca tcatgcattt gaattccaaa tggatctgga
    66481 aactgactcc ttacctttat ggtttggggt tagtggtaat gggactcttg ctcaaattct
    66541 atgatcagaa tttagctgct tcaacagggt ctaaaaactg gtttcgattc ggtgcgttta
    66601 ctttccagcc agcagagttg atgaagattg cgtacatctt gatgatggca ctgatcgtaa
    66661 ctaaacataa tacgcaagta aaagaacgga cgatgaaatc ggacttttgg ctgattggga
    66721 agctcttgat cgtgacaata ccggttttag cattgatcat ggcccaagat gactttggaa
    66781 cgatgcttgt ctttcttgcg atctttggcg ggattttctt gatgtctgga atctcttggc
    66841 gcatcatcgc acctgtagta atcttggcag tagtcgttgg agcaggaacg atcttcttgg
    66901 ttacgactga aggcggaaga gacttgcttt acaaagttgg cttcaaatct tatcagtttg
    66961 cacgtattga ttcatggctg gaccctttcc atgatacgtc aggaatgagt tatcagccgg
    67021 cccaaggact tttggcaatt ggtaccggtg gcttgtttgg taaaggattc aacgtaagca
    67081 atatttatgt gcctgttcgt gagtccgata tgatttttac cgttatcggt gaaaacttcg
    67141 gctttatcgg tggtgcattc gtcattttct tgtattttat tttaatctat cgtatgattc
    67201 gggtgtgttt cgatacgaat aatgaatttt acgcctatat cgcaagcggt ttgatcatga
    67261 tgctgctgtt ccatgtcttt gagaatattg gagcaaatat cggattactt cctttaacag
    67321 ggatcccatt gcctttcatt agtcagggag gatcttcgat tttagggaac atgatcggta
    67381 tcgggttgat attatcgatg agataccaaa atgaagcacc tgcaagatct tcaaggaggt
    67441 aagaaaattg tacacctttt actggtaccc gaaatgttca acatgcaaaa aagccaaagc
    67501 gtggttagac cagcatggcg ttagttatca aactgttgat atgatcaaag aagtaccgaa
    67561 ggcctcaacg attgagactt ggctagaaac gagtcaagta ccaatccgtc gcctgttcaa
    67621 cacaagcggg atgaaatatc gggaacttgg actgaaagat caagtaggcg agtttacggc
    67681 ttcaaaagcg agccaagtct tatcgacaga tggtatgctg atcaagcggc cactgatctt
    67741 acgagaggac cagcttgttg caattggatt caatgaaaaa atttatgaag gagaactgat
    67801 ataaaatggc aggcaagcat ttgaagaaaa aggacaacct ttggatctta tttaatggaa
    67861 aagaatactg tgttggtttg acaaatgaag cgcaagaaga acttggagac atcacgtttg
    67921 ccaatctgcc aaaagcagga caatcgctaa aaaaagatga acctctgatc gaagttgaag
    67981 cggaaaaagc ggtcaatgaa tttgccagcc cgctaacggg tacagtttct tctgttaatg
    68041 ataaaatcgg tgaagatatc aatatcttga atgattcaga tgaaatgaat gcgtggatct
    68101 taagtttcaa agatgttgat ccaaaagaat ttgacgaatt ataaaatcag aaaatcactt
    68161 gaaaaaagtt gacactgatt cttccagttg ctataatcat aagcaatcct atatgaaacg
    68221 agaaagcttt gaaaagaaga gtacatgtca cggacgtttg aagagagccc tgtttgctga
    68281 aaatgggtaa cgaaaatgag atggaagatg gtcttagagc agagtaagcg agcgtaagca
    68341 aacttactac gggagtgccc gttacagcgc gacagtatac ggaaagaagc taagtccaag
    68401 tactggaaga ggctgttatt gcgaagtaac ggtaaatcaa ggtggtaaca cggaagttca
    68461 agctttcgtc cttttgctta aggcaagagg gcgaaggctt ttttgtttga aaaatcataa
    68521 gagaaagatg tgaatggcat gtcattaatc caactaacga atgtcaaaaa gacattcaat
    68581 gggaaaaacg gaaacatcca agccgtcaat gacgtttcac taaacgttga aaaaggggat
    68641 atttatggaa tcgtcggcta ttctggcgca ggaaaaagta cattagtccg tctcctgaat
    68701 ggacttgagc ttcccacgag cggcgaagtg atcgtaaacg atcaagatat tacaaaatta
    68761 aaaaacaaag aattacgtac attccgaaag aaaatcggta tgatcttcca gcatttcaac
    68821 ctgttatggt caagaactgt acttgaaaat atccagctgc cgctggaatt agctggcgta
    68881 ccaaagagca aacgtaaaga acgggcagaa gaactgttgc gtttagtcgg gttagaagga
    68941 cgcggacaag catatccttc acaactttcc ggcggacaga aacaacgcgt cggtatcgca
    69001 cgagcattgg caaatgatcc tgagatcctg ctttgtgatg aggctactag cgcattggac
    69061 ccgcaaacaa cagaagaagt attagactta ttgttagcga tcaataagaa attgaatttg
    69121 accatcgtct tgatcacaca tgaaatgaat gtgatccgca aaatctgcaa caaagtcgct
    69181 gtgatggagt tggggaaagt cgtagaagaa ggagacgtat tgactgtctt cagacaaccg
    69241 aaaaaagaag taaccaaacg ctttgtacaa caagacatcg aaccagaagc tgattcgaca
    69301 gaactattag ctgaactcat caaagaaaat ccaagcggcc gtttggcaac tttgaccttt
    69361 agcgaaagaa atgccaacga gccagtcatt tcccaagcga ttcgacgcta taacatcgat
    69421 gtcaacgttg tgtatggaaa gatcaaacaa gtgaaagaag gttcctttgg ttcattgact
    69481 gtcttgatga ctggtgaaac caaagaatta gatcaagcag aagtgttcat caaagaacaa
    69541 ggagtaggaa ttgaggtgat ccatcgtgga taaaagcttt tcagaaacat atctagattt
    69601 taaacaaatc aacccggaaa cgatgaatca ggctatcctt gatacactat atatgacatt
    69661 aatctcaatg gtcttagtga cgatcatcgg attagttttg ggattgatcc tttactctat
    69721 tggacgcaaa aacaaaccgt atgctcgaat catttatgga atcgtatcga tcatcagtaa
    69781 tattttccgg tcaacgccat ttatgatcct gatggttttg atcattccat ttactaaagc
    69841 aatcgtaggc actatgctag gtgcgcaagc agccattcca gctcttgttt tatccgcagc
    69901 accattttat gcccgtctag tagagattgc ttttcgtgaa gtcagccctg gtgtactgga
    69961 agcagcagat gcaatgggag caagttactg ggaaatcatc tggaaggtct tgatacctga
    70021 aagtattccc gcattgattt ctggattaac agttacaacg atctcgatga tcggatttac
    70081 tgcgatggcc ggcgcgatcg gcgcaggtgg acttggaggt cttgcttggc aggaaggcta
    70141 ccagcgtggt aatctgacag tgacattcgt tgcgacttta attattttac taatcgtatt
    70201 tatcgttcaa ggaatcggtg atttcttaac taagaaaaca gacaaaagat aataggatat
    70261 agggggatgt aggatatgaa aaagaaaatt tttggatttg cagcagcgct tttgctgact
    70321 gtaggattag cagcatgcgg taacaacagc gacagcaaag attcagcaaa taaagcagac
    70381 gacacgacat tgaaagtcgg cgcttcaccg acaccgcacg cagagatttt ggaacatgtg
    70441 aaaccattat tgaaagatga aggaatcgat cttgaaatcg tcaaattcga tgactatgta
    70501 ttaccgaacc aatctttgga agaaggcgac attgatgcca attacttcca gcatattcct
    70561 tatttgaaca aagaaatcaa agaaaaagga tatgactttg tcaatgccgg tgctgtccac
    70621 atcgaaccaa tgggcttgta ctctaaaaaa gtcaaagatg tttccgaatt aaaagatggt
    70681 gcaacaatca ttacttcaaa ttctgaatca gactggggac gcatcatcac aattctacaa
    70741 gatgctggct tagtcaaagt caaagatgga gtagatctgg aaacagcaac attcgatgat
    70801 attgaagaaa accctaagaa cttgaagttc aaccatacga tcgacccatc acttttagct
    70861 tctacgtacc aaaatgatga aggtgaccta gttgcaatca acgcaaactt cgcttacggc
    70921 gcagggttga atccattaga agatgccgta ttgcttgaaa aggacaactc tccttacgtg
    70981 aatattattg cgactcgtaa aggtgatgaa gacagtgaca aaatcaaaaa actgattgaa
    71041 gtgcttcacc gcaaagaagt ccaagaatgg atcacagaca aatggggcgg ctctgttaaa
    71101 ccagtaaagg ctgatgcaaa ataaggtatg gaacaaaaaa gatgagaaat aagtctgtaa
    71161 tggcttattt ctcatctttt ttatacctat tctaatttag aaatcaaaat tgtttaataa
    71221 taaataaaag atatttgatt ttagtaagga aggtcattgc gcttcattct caattagtct
    71281 aaaatgagtg agaacgaaag agaatttggg ggtataatgc atgtctgtct tagaaataaa
    71341 aaatctacat gtgtcgatcg aggaaaaaga aatccttaaa ggcgtaaacc taacaatgaa
    71401 aaccggagaa atccatgcca tcatgggacc taacggcaca ggaaaatcta ccttatctgc
    71461 cgctatcatg ggcaatccaa actatgaagt aacagaaggc gaaattttgt ttgacgggaa
    71521 aaatgtttta gacttggaag tagatgaacg tgcgcgactt ggcttatttt tagctatgca
    71581 atatccaagt gagataccag gtatcacgaa tgcggaattc atgcgtgcag cgatcaatgc
    71641 gaaacgtgat gaaaacgaca aaatttctgt tatggcattt ttgaaaaagt tagatgaaaa
    71701 aatggcttta ctaaatatgc cagaagaaat ggctgaacgt tatctgaacg aaggtttttc
    71761 tggcggagaa aagaaacgga atgagatcct gcaattgttg atgttagaac caacatttgc
    71821 aattttagac gaaatcgatt caggtctgga tatcgatgct ttgaaagtcg ttgctaaagg
    71881 agtaaatgaa atgcgcggag acaatttcgg tgcattgatc atcacccact atcaacgatt
    71941 attgaactat atcacacctg atgtcgttca catcatgatg gaaggccgag tagtcatgac
    72001 agggaatgct gacctagtta aacgtctgga agcagaaggc tacgctggta tcagtaaaga
    72061 attaggaatc gactataaag aagaagaagc gtaaggggga gcaagaatga aagaaaaaaa
    72121 ctggctcgat tatcttgacg cggtaaatga tttttcttta agtaaaggcg aacctgattg
    72181 gatgagaacc ttccgtcaag acgcactagc gaaagcagat gaactgccat tgccgcatat
    72241 cgatcgggtg aaattccatc gctggtcgtt atttgatgtg aaagaaacac aaaccatcag
    72301 tgaaacaggc acgattccgg catttgatgc aatgaaagac aatcctgtgc ttgtccaaca
    72361 aggttcatgg acgatttttg aacaactgcc tgtggaatta gcagaaaaag gagtcatttt
    72421 taccgacttg ttcactgcaa tgatcgaata tccagaacta gtccaagaat attatatgaa
    72481 aaaagcagta aacatgaacg aagaccaatt gactgcactc catgtagctt ttatgaacag
    72541 cggtattttc ctgtatgtgc ctaaaaatgt cgtgatcgat gaaccactcg agtccttatt
    72601 cattcaagat ggcgcatccg atgagcactt cttcaagcat gtgttgatcg tggcagatga
    72661 acatagtgaa ttttcttatc tggaacgttt ccagacaacc aaagaacaag tagcaaaatc
    72721 atcaggtaat atcatcgtgg aagtcatcgc taaagctggt tcaaaaatca aatattcagc
    72781 cgtagatcaa ttaggagaaa atattacttc ttatatgaat cgccgtgggc acattttacg
    72841 agatgcttct gtcgactggg caattggtgt catgaatgac ggtcatgtga tcgctgactt
    72901 tgactcagat ttagcaggag aaggtgcaca cgcagaagtc aaaatcgtgg caatcagctc
    72961 gggcagacaa atccaaggaa tcgatacgcg agtaaccaat aaagcccctc atacgatcgg
    73021 gcatattttg caacacggag tgatccgaga aaaaggaaca ttgaccttta atggtatcgg
    73081 ccacatcttg aaaggggcaa aaggtgcaga tgcccaacaa gaaagtcgtg tcttgatgct
    73141 ttctgataaa gcacgtggtg atgcgaatcc tattcttttg atcgatgaaa acgaagtaac
    73201 tgctggacat gctgccagtg taggacgagt tgatccagaa gaaatgtact atctgatgag
    73261 tcgaggattg cataaagaag aagcagagcg cttagtgatt cgaggattcc tcggttctgt
    73321 cttaacagca atccctgtag aacaagttcg gaaagaatta gtcgaagtaa tcgaagggaa
    73381 gttgaatgga tgatcgatgc taaaaagcta cgcaatgatt ttcctatctt atttcaagac
    73441 gtcaatgatg aacctttagt ttatctggat aatgcagcga cgacccaaaa gccaaaacaa
    73501 gtactccagg cattagcgca ctattacgaa cacgataacg ccaatgttca tcgcggtgtc
    73561 catacgttag cagaacgcgc gacccatgat tatgaacaag caagagaaaa agtacgggcg
    73621 ttcatccatg caaaagaaac agcagaagtg ctgtttactc gtggtacgac gacaagcttg
    73681 aattgggtag ccagaagctt cggcgaccgc tatatcaaag caggagacga gatagtgctc
    73741 tcttacatgg aacatcattc taatgttatc ccgtggcagc agttggcaaa acgaacaggt
    73801 gctgtcttga aatatatcga actaacagaa gaaggcttcc tggatatgga ggatgcagcg
    73861 aaaaagatta cggacaaaac caaaatcgtc tccattgctc atgtatccaa tgtcttaggt
    73921 gtcatcaatc ctgttcaaga attagctgaa cttgtccatg aaaacggcgg ggtcatcgta
    73981 gtagatggtg ctcaatctgc cccgcacatg accattgatg ttcaagcact agactgtgat
    74041 ttctttgctt tcagcggaca caaaatgtgc ggaccaacag gtatcggtgt tttatatggt
    74101 aaacgaaaat ggttagaaga aatggaacct gttgaatttg gtggcgaaat gatcgatttt
    74161 gtcgaattat acgacagtac atggaaagaa ctaccttgga aattcgaagc agggacacca
    74221 aatatcgctg gcgctatcgc attaggtcat gcaatcgatt atttgcaaga actcggcatg
    74281 gacaatatcc atcgatatga agaagaacta gccgcttatg tgttgccaaa attacaagca
    74341 atcgatggat tgactgttta tggtccgcaa gacccgaatt ttcggacagg agtcattgcg
    74401 ttcaatttgg atgggttaca tccccatgat gtcgcgacag ctttagacat ggaaggggta
    74461 gccgttagag caggtcatca ttgtgcgcaa ccgctattga agtaccttga agtatcagcg
    74521 actgctcgcg ccagctttta tttctacaac acaacgcaag acgccgaccg tttagttgaa
    74581 gcaatcatgg caacaaagga gtttttcaaa catgggacta tctaaattag acaatttata
    74641 ccgtcaagtg atcttggatc attcttccca tccacatcat cgtggaagct tgactgactc
    74701 gacaagcaag atcgaattga acaaccccac atgtggagat gtgatcgaat tgcaagttga
    74761 tgtaaaagat ggaatcatca aaaatatcgc ctttgacggc agcggctgtt ccatcagtac
    74821 agcaagtgcc tcgatgatga cagatgccgt cattggaaaa tcaatagaag aagcagaaca
    74881 tttaactgta gactttctac agcttgtcca aggaaaagaa gtcaaagatc ccgaccaatt
    74941 aggcgatgct gctatgcttg gtggtgtagc taaatttccc gctcggatca aatgtgcgac
    75001 acttgcctgg aaagcactag gaaaagcaat ggaaaacgat ggtaccgcag ctttccatca
    75061 ttaccacaag gaagaggagt gagaacatgg gcgtaccaga attagaagaa tataaattcg
    75121 ggtttcacga tgatgtcgaa ccggttttca gtacaggaga aggcttgaca gaagaagtga
    75181 tccgtgagat gtcaagaatc aaaggcgaac cagaatggat gcttgaattc cgtctgaaat
    75241 ctctagaaac attcaataaa atgccaatgc aaacatgggg gcccgacctt tcagacatcg
    75301 atttcgatgc catcaaatat taccaaaaac caagtgacaa acccgctcgt gactgggaag
    75361 acgtaccaga aaaaatcaaa gatacatttg aaaagattgg tataccagaa gctgaacgag
    75421 cttatctagc cggtgcttcc gcacaatatg aatcagaagt cgtgtaccat aatatgaaag
    75481 atgaattcga aaagttagga atcgtcttta ctgacactga ctctgctttg aaagaatacc
    75541 ctgaattatt caaagagtac ttttcaaaac ttgtaccgcc aaccgacaac aaattagcag
    75601 cgctgaattc agccgtatgg tcaggtggca cctttattta cgtgccaaaa ggcgtcaaag
    75661 tcgatgttcc attacaaacg tacttccgga tcaatgcgga aaacacgggg caattcgaac
    75721 gtacgctgat cattgttgac gaaggagcaa gcatccacta tgtcgaaggt tgtacggcac
    75781 ctacttattc aagtaatagt ctgcatgctg ccatcgtaga aatctttaca agaaaagatg
    75841 cgtattgccg ttacaccacg atccaaaact ggtcagacaa tgtgtacaac ttagtaacca
    75901 aacgagcaaa agcatacgaa ggcgcaaccg ttgaatggat cgacggaaac ttaggtgcaa
    75961 aaacaacgat gaaataccca agtgtttact tagatggaaa aggtgcacga ggcaccatgc
    76021 tctccatcgc ctttgcagga gcaaaccaaa tccaagatac gggtgcaaaa atgatccata
    76081 atgcaccaaa tacatctagc tctatcgtct ctaaatcaat ttcaaaagac ggcggagaag
    76141 taaactatcg aggacaagta acctttgcca aaaacagtgc gggttcgatc tctcatatcg
    76201 aatgtgacac gatcatcatg gacgaatggt cgaaatccga tacgatccca ttcaatgaga
    76261 tccacaacag ccaagtctct ttagaacacg aagccaaagt ctcaaaaatc tcagaagaac
    76321 aactctacta tctgatgagc cgaggcctga ccgaatctga agcaactgaa atgatcgtca
    76381 tgggctttgt tgaaccattc accaaagaac ttccaatgga atatgcagtc gaactcaacc
    76441 gattgatcag ttatgagatg gaaggcagtg taggataaac ttgttatagg agctagaatc
    76501 cttggtatat aagggttcta gcttttttat tttgtctata tactagaaat gaccagcttt
    76561 tgaccagctc ttttactgat gagccatcat atcagcaaag tcttgacctg ttttcttagg
    76621 tgcattattt gtaatatgtg catagatgtc taatgtcact ttactatttt catgccctaa
    76681 tcgttgttga actaccttga cagattctcc tgcttctaat aataaactag catgtgtatg
    76741 tctaaaccca tgaggtgtaa tacgaggcaa gttatatttt ttcaaaatat atcttaacca
    76801 atcattaaca gtgtttggaa tgtatagagt gtttttaact gttgtaaaaa catgttgctc
    76861 tttagagcta gtattgtatc caagttttaa atactcttct ttttgctgta atttccagtt
    76921 gttgaggata gaaagagtct cagtatctaa agagataact cgtctagaag ctcttgtttt
    76981 cggagattga attataactt taccaaattc atctacagca agagttttat tgacatgtag
    77041 ttctttatta aacgtgtcta tgtctttcca ctgtaaagcg agtacttcac tctttctcat
    77101 acctgtgtat gccaataatc tgaagaaggc gtattgtttc atgttaccaa aatctttaaa
    77161 agcatccagt aaattattaa gctcctcttt tgagtaaaat ttacgatttt tctcatactc
    77221 tttttttcgt ggaagaagtg ttttttccat aggattattg tcaatatatt gcattgcaac
    77281 cccgtagcgt aaaatttgtg cagtctgttt tctcatataa tcgtaacttt catatttact
    77341 gtgccattca tctaccactt tttgacaata tgggacagag atattcgata gtttaagctt
    77401 accaaatgct ggaagtattt gattatttgc gtatcttact gagattgcga ttgttgaagc
    77461 tttaacactg gtacgctgat gagttatcca ttcattatac aggtcttcaa atgtcatatc
    77521 aggtgctttc tttttaacac cgtataatat ttgatgtctg tactcgtcat aatctttttg
    77581 agcttcttgt ttgctactaa aacctcttct cgtagtattt attttttcac cagttcgtgg
    77641 atcggtggca atgtgtcctt tatacatcca cgccacttga ccgtttttct ttttgtactt
    77701 tgatattttt gccatgaaat catctcctct tagtttacaa ggagtactta ccactagatg
    77761 gtatcacctc ccttcatttt tttcttagtg tattttttcc caattgatga aatcgtttgt
    77821 tttagcttgt ttatattatc aataatttcg tttacagctt cttcgggata attcatgtct
    77881 tccacttgac tatgtatccc ttcatctatc atttcttcta gttgttcctc tatactgcta
    77941 gtgagcagaa gaatgttatt gtcaaattct tctataatag cattgatgaa taattcttct
    78001 atttttaaga tattgaaaag actaattttt tcatttttaa ctttattaca agtcttgtta
    78061 gcaataaatt cttgcatctc tggttctaat ttggaatatc tatccagcca tgtatctaaa
    78121 ttagagtgta ctggtgggaa ctgttgacga agatgctgga acaggttttt atctggaaat
    78181 gttataccat ctagtacaat gctatctcta taaagaataa ttcccaaaat atattcttct
    78241 acattgccac aaactaactc ctctatactc atatttccca aatcagcaat tcgggataat
    78301 cgctctggta ttggtaaata ggttcccttt tcccattcgt agatagtttt tttgtcaatc
    78361 aattgaccat tgttaatcat aagaccaaat gctggttgtg ttaatttttt actctttctt
    78421 atagctttta tttttgttcc gagtatcttt tttcgttcta aataatttat tggtggacgc
    78481 tttatcatat tgaccacacc tcctaaaatt agtatacctc aaaaaggggg tgttgtaaat
    78541 aaattcacac aacatattga cacccctttt gtatcgaggt attatgtgta tgtcgatgaa
    78601 ctgataatca ttttttattt gattaatcgg ttaataacaa caaaatactt ttattttgat
    78661 caaataatac gaagatgatt cttagaaaat ttgttcaagt aatcacgaaa ggagggggaa
    78721 atatgtctct acaaatcatt gatagcattg tttctataca agttgaacaa caagtgaaag
    78781 agataattac agtgctaaag cctatgctag aagacattat ttctggtgtt actctagagt
    78841 atatggacta tcagcaggca agtgaatatc taggtgtatc agtaggaacg attagaaaat
    78901 atgtttctca atacgggtta cctgttataa aaattgatac ggtcattaga ttcaaaaaat
    78961 ctgatattga tagtttcatg gaacagtata aaggttgagt aaacaaataa gactaaaaca
    79021 tatagtaata aagagtttgt gtttattatc tgtatgtttt agtctttaac agaattttat
    79081 aaggaggaaa cacaaatgga aacatcaatg attaatattc caatttatgt agatcaagaa
    79141 aaattattag agaagccagt tacaaaaaaa gaaaaaactg atgtaagaga taggtgttta
    79201 gataactata gagaagttac aagagatgag tttgtagaga tactaaattc atcacaatca
    79261 tttattccaa gcaagacaaa gaataaaggc aatgacaagg agagttttgt ggaaaccaga
    79321 gtaattattc tggatgtcga taacactgtt aaagatgaga aggggaaggt agtagatttg
    79381 agtaaagatg atagtagata cttaagcgta gaaaaggttt tatctatcaa tttagttcat
    79441 aattctgcgt ttgcgataca aaaaagtatt cggtactctg aaaatctaga aaaatacaag
    79501 attgtctttc tattaaaaga agcaattact gactatggta aaatggttgc tgtttacgaa
    79561 tacttgaaaa agaacatccc cgggtgtgat gacaatgtaa atgcttcgaa tagaatgttt
    79621 tttggaggat ataagtcaga tgcagtgata ataattaatg aagacaacat gttagatatt
    79681 actgagcttc cgattgattt taccatgaca tgttctaaaa attgtcaaag tgattcaggg
    79741 agagagtatg aactagtcaa tgaaaccgat tttgttaagt tgataaaaaa tgacgacaaa
    79801 gaagaaatga aacagtggtt taaagactgc ctgtttgatt cctccgacat gtcttttaat
    79861 gagatttatg aaagattgtt aaccattgat atgaataaat tacttaagtc aagtaaaaac
    79921 ttaagatgtc tgtttcacaa cgatcataat ccctctgcta gtatttttac cagtaaaact
    79981 gggcattcca ttttttattg tcattccagt aattgtgata tcagtgaaaa ttttattgga
    80041 gttgtgatgc taattttaaa gaaagacagt cgggtagaaa catttaattg gctattagag
    80101 aacctagact tgtatcctac acattttcga aaattgaaag aggaatcaaa agtacttttt
    80161 gacactcttg aatcaatgaa agacaaactt ttcaggacaa taaggaatta tctagaggaa
    80221 atgcgacgtg tctatgatgt cttgctttct gatgttaatt tttttgatga tagtaaggaa
    80281 agtgtgactt gtattttgtc gggggaacaa ttagctaaaa aaatgagttc ttactatggt
    80341 aaaacttatg acatagataa atgtaataag ttactatcac ttatgacttt tataggattg
    80401 ataaaaaaat tagatgatga agatgttcct ttgaagatgc tcgaatacct aaataggtta
    80461 aaggaagaga aagcgttagg aaactttaat cataagagaa gcaatgtcta tcgattagac
    80521 gtttttaatg caacttctgt gattcaaaaa ttgaatgaag atatccttcc acttctggaa
    80581 aaaattcatt ttacatatca atatttttct tatgaatggg ttaagatatg ttttaacgaa
    80641 aaagaggcta aaagagtatt tcctcaaaat tcccgatcag aactcagcaa ggaaaaacaa
    80701 ttgattttag atgaagcaca tgaagtttta cagggcttat cgtggcaagg gacatatcta
    80761 atgacagaga aagaacttat taacactgtt tgtgaacgcc tacgtaatgt tggggataac
    80821 agcgtgaaaa atgctttaat aaaaaacaga ggctactttg ttaaacaagg attcactctt
    80881 gaacgagctt ctaaggatat taagaaacta tacaatgtga aagcaagtag tagtttttta
    80941 atatatttag cgaaaggggc agggatagat gaaacaataa aagaattgat attatcagga
    81001 gctgggatag ttcctctgta tcaatttaca agtgtaacaa gagatgatgg acggagagta
    81061 aggaagagaa aagacccaat tgtattaaac tagacaggtt atccatagct cttaatctta
    81121 tttcatctca atacacccac cgttaaagtt cggtgggtta tttatttttc aatctttcaa
    81181 tagctgattg cgttcatttt cttgcctttt taatagcttc atatagtcaa ttgttcgaac
    81241 tgcatcttca gtgctaagag aacgatagag agccaaaaac tcttcctcat aatctacgac
    81301 aacattgtct agaaaatggc ttacaggggt tcctagggct ctagaaagag ctgttaagct
    81361 atcgaggtta ggctctgtta cagaattttc ccatcttgct actgcctgtt gtgtagagaa
    81421 gattttttca gctaattctt tttgtgtcca cccgagagct tttcgctttt ctctaatgac
    81481 cttcgcatat tgtttctgtt tcattaatac acccccatct cagtatagta caacaagttg
    81541 ttgtatttgt aatggtattt gaagtttttt atattttatg agttgaaata catcatattg
    81601 ttgtatataa taaaacagga ggggagaatc atgaaaaaag taagtaatct cagccgatac
    81661 agaaaagaaa aaggactttc tcaaacggag ttagccaaaa aaatgaatgt tacacagcaa
    81721 tgtgtaagtt cgtggcaaac agggagaacg attcctaaac cctatcaaat gaaaatgctt
    81781 tctgagatat taagtgtacc aataaacgag ctgttttctg atgtgtttaa taaagtaaac
    81841 agttaactat taagcaattg aatgatttta ggaggagaag acatgtattg tagaaaatgt
    81901 ggtaaagaaa taacagatga aagtaagtat tgccagtttt gcggagcatt acaagaaaca
    81961 gatgagacaa ctggagcaga cgaagtaaag aaaagtactg agcagacatt tagtgaaatg
    82021 aaggaacaaa tcgtacatgg acaagagaca gggaagctgt atttgattat tggttgggtt
    82081 tctatggtag tatcgttagc atttattcct gttgtatttg gtgctgttgc tgttattatg
    82141 ggctacttat atcgagaaac agatgagaaa atgggtacga ttttgatgat agcaggggta
    82201 gctggagcaa tctttggtgt acttttaggg atgtcaatgt actgataaga gggataagag
    82261 caaattattt tggagatagg agataaaaag ttgaataaag taaatatgaa caagaagttt
    82321 gtcattatag gtatcgttgt cttggctatt ataggtatca ttttttcaaa aatgacaggt
    82381 acatctggat tagagaagtc atctaaacca ttggtgacac agattttaca agaacagtac
    82441 aacttaaata ggtcatgtga tgatgtgacg attactcatg aaaatggaga taacacatac
    82501 cgggctaaag ctacgttaga caatggaagt gctatcaata taaatgtcga gtactatcca
    82561 aagaaagacc gtgtatatgt agagatacca tatactgagg tgttaatgtt aaattgattt
    82621 aaatgtatta tgtataccgt ccaaacagga actcctaaag gtgtaagctt actaaggagt
    82681 ttttttgatt ccctgtaaat aaaatactaa tatagatgag aaaaataatg ttataataat
    82741 tgatggaaat tgtttttaaa gagctttaaa aattgggttc ttacattgtt gattaaatgc
    82801 tttaaaagag gagctttatg atgaaaaaga attatttaaa aacaggtata tttttggtta
    82861 taggaactat actggttatt caattatcag gttgtagaaa taaagataaa gatttctatg
    82921 gatattggtc aggaactgct gagaaaattc ctgtagacta taattttaaa ataactaaag
    82981 acagagtaat agaactacaa aaaaatggtg aaatggtgga ttttaagtat actctaagac
    83041 ataaaaaatt tgattcaact acatttcgtt caatcatgat atcaaaagat gaattagtta
    83101 aagcgattcc agaattaaag gaaaccacgg gaataagcaa tataacgttc atgcctattg
    83161 acggtgaaaa agataaatta actgtgttgg taaatttgga tgaacactta tcaacagcca
    83221 ctctttatag gactacgaaa gatgagagtc caattggtaa ggtagaaaag aaaaacgata
    83281 caatatcaag acaaactgta gataaaaaaa ttgatacgtt cataaaaaca tacgcggcta
    83341 taccacctac ttggaaactt gtaaatgaag ataagggaat aacgataaat actgatacag
    83401 agattccgac tgatgctcaa tctttatcag atttattagc taatctaaca ggagtcagta
    83461 atgcggtgtc agagcaagtc ggtaaagata ttccacttag gttacttgaa aatggaaaaa
    83521 aagattattc tgtggtattt aagaacggaa aggtaactga ttacaacgaa atatttgaga
    83581 aagtcattga ataatggttt ttctatcttt ttattaacta ccctaccccg ttgttttttg
    83641 accgtgtttc gagaggaatc attagaaagc ataggctaac taggggtttc tttttctttt
    83701 attttttggg aatccgctta agtgaaatgt atctgaaatg aaacggagat aaagtgattt
    83761 tttgctgtaa tgacaaggtt ttagctgttt cagataccat gtaacccaaa atagtttatt
    83821 gagaaaatag gagagtattt gatactaact agtagggaaa aatgagataa aaagtaaatg
    83881 gaatcatttc aggtaatctg aaataaaaaa atatacagtc ctgtggcact ttacctatgg
    83941 gactgtatat tttttactct cagcgttttt tgactccgtg tctgactccg ttttattgat
    84001 tttatatgtt attcagtgac cctttaacag gtcaattttt atgtttttgt cttcgtatga
    84061 ctcagtttga tacctagtga tttccatggt aatacgggat gttgaacaag ctagagaagt
    84121 tctgcagggg ttaattgcaa acaattcaga taaacaaatt acaatagatt atttcaagag
    84181 ggaaattaaa aaatcagagg aaaaatattt agatttaaag tcggatatcc tattagcaga
    84241 cgatataggt tcactaactg tcgaagaaga tagcctattc tacgtctatt gtgcattgac
    84301 ttcgtaaaag aagacgtctt ttccaggtat acagttcttt tatctacttc atatgaaaat
    84361 ttgggtacaa acgacaagga agtcagtttt ctggtcagac tatcgtacga acatcttgtt
    84421 gtggtattta cactcagctt tgatgatgag tacaagagtt tttcagcgaa caagacagaa
    84481 catcgaaaga ggtttccaga cgaagtttta caggctgggc tgaagtatta tcaagaagga
    84541 ctcaccatta agaagtcttt atcgagaata taagaagata caggtataga agtcagtcgg
    84601 tcaacattct gtgattacct aaacagcaag gagtaacagg tgaacgggaa aaagagcaca
    84661 gggagggcta tgttcactgg ctgaagaagc aagataaacc tgtttatgac ttgttctttg
    84721 aaataaagaa agctttagat agtcagtcat tagagaactt cattgatggg tatgatgaaa
    84781 agttatctaa tgagcaaatg attgcgataa tgaaagaggt gtttcgtcag tatgggttat
    84841 caaataaacg taggaaagag gtttttgacc acgttaagac aataatgagc ttttaccaca
    84901 cgaccctcgg ctaaatctaa agagggcgaa aaagggacga gtggtaaaat ttaatgggaa
    84961 tagctaaaag taaataataa taagtcaaag actgcctagt ttggtggtct tttttcatgt
    85021 tcataaaaat aaaataggac agacgaacat cttcgctaac tcccctgtgt tgcaagaggc
    85081 aaactctata attctccagt taagctatat tttgttcttt attttgagat agaggaaaaa
    85141 acaaaaatgt gttaaaattg aacataagca taattagaaa ttgtcgagtt ttttcaagta
    85201 aaaatcttga cttgtaagga ggaaaagggc atgatgacac gcaatcacag tactagccag
    85261 cagtctgccc aaaagcccat atatgaaagt gataaccgat tcgtagcatc cgtttcggtt
    85321 atttgtgttg ggaagatggg tgatttttag tggttgaaga tatggtgatg gttgaagagg
    85381 aacaaggacg actaatcaaa agtaaaaaac gtgtccagaa gcacggtgag gtatttacac
    85441 cgcaaagaac tgtcaaagat atgttggatt tgccaggcat aaaagaggct tgcgaggagc
    85501 tgcagacgac tttcttagag ccttcagctg gagaaggtgc tttcttagtt gaggttttga
    85561 ctagaaaaat ggcaatggtt gctcgtgaat ataatgagtc cctagaacag tatgaaaatt
    85621 actccttact ggcgctttca actctatatg gcgtggagtt actcgaagac aatgctcaga
    85681 cctgtgtaat gaacatgttt caagtattca acgatttgta cagagaacaa tcgaaaaaac
    85741 atggtaccgc aatgaaaagg aaagtccaag acagtgcaaa gactttgatt tctaggaata
    85801 tcaaacaggg agattttctt acaaaacgaa caccagatga taatccgatt atttttagtg
    85861 agtggacacc taagacgcta agaaaaggac agaaaaaaat cactgtaaat cgaactgaat
    85921 attctttgga ggatatttat tcaggggtaa cacgagagtt tggagaggca tactcagctc
    85981 tgcctgtatt tgaacagctc gatttgtttt catttgatga cgaggtcgat gaagaagttt
    86041 caaatgatcc aatattacgt tatgtagcga tgccgataac tgaggtttat aaggaagaga
    86101 tggaggaaat tgatgacgac agcgttgaaa tctaaagcta aatacttcga ttacttacct
    86161 aaatatggtt ctaagctaga acacttcctt gggattccta atttagtaga tgcaattaac
    86221 acgtaccgtg taaccgttaa tcaaatacct aatgaagttg ctattggaac tagacgttat
    86281 tcggaggtag cagcacggaa gattgcttca aatgtgggta ttgaccagca aagtatgaag
    86341 tatgttgatg tacttcgcga gcttagggtc agaaataata ttactcctac gatagctgac
    86401 ttatttcata agttgagaaa atatggaaat gttgcagcac atgaaaatgg aattatacct
    86461 gtttcagagg cggtcgaatc tttagttact cttgatacct tgctaagagt ctttgcacgc
    86521 aatctgtctg gggataaatc gttaaaccca aaggaagaaa ttacggatga gatgtttgtt
    86581 atcacctata acacctttga ccgtaaactt atttacatcc agagtgccaa ggatgctgac
    86641 ggcacatgga aaatgtacca aggactggaa aagattgggg atgcatcagt accagagaat
    86701 tatgaggcag actttactcc taatagcgag tatttaagag agtatgcaag tagaagaata
    86761 aagcagtaca tgacaacagc gggggtacct tttgtccttc attgggcgca attggctgtt
    86821 aataagaaga accaattttt ccgtgaccat gacgtgcatg aagtattaaa gcgttcgggc
    86881 tataatcctc aaacgattgg cgaagatgac acagggaagc ctaatgagtg gttcagtgta
    86941 acagttgacg ttgccaagaa agcaatccaa gcggttaaag atggtaaagg tagtcttgac
    87001 tcagaaaaag atgactttga cgagttcaaa attaatttta gaccagaaca aaaagatgct
    87061 attgagcaga ctaagactgt attcaaaacg aaagatgaga tgctttggaa tgccaagatg
    87121 cgttttggta agacgctttc ttctcttcaa gtgattaaag agagccaata caaaaaagtt
    87181 cttatcatga ctcatcgacc tgttgtaagt gatggttggt ttacggattt caaaaaaatc
    87241 ttcacagatg gttcgtacat ctatggttca aaacaagatg gagaaaagat tcaaaacctt
    87301 gttgataccg aaaaaccttt catctatttt gcaagtattc aggacttacg cggttctgag
    87361 tgggcaggtg gaaaagcagg ggataaaaac tatgaattct tagcgattga ctgggatttt
    87421 attattattg atgaagctca cgaaggaaac gaaacggaat tagctaataa cgtaaaggct
    87481 aagttgcgga aagagcatac caaggtctta gagctttcgg gtacaccatt taaccttttc
    87541 gataagtatg atgaggataa tattttcact tgggattata ctatggagca agaagctaag
    87601 gagaaatggt cagtagagca tcccaatgaa cctaacccat acgaaggttt accgaaagta
    87661 tctatgttca cctttgaaat accaaataaa tttgattatt tcgatgaaaa taaggcattt
    87721 aacttccgag aattctttag ggttaaggaa gatgatgaaa caaagttgct tcatgaaggt
    87781 gacgtacgca agtttcttga ttatattact acaaacgatg aaaagactaa ttttcctttc
    87841 tcaaaaccag agtttagaga aaacttacgg catactttat ggctgatgcc gggggttaaa
    87901 gaggcaaatg cttttgaaag agtgctcgaa acgcacccta tattcaaaga ttacaatatt
    87961 gcaaacgtag tcaagacagg tgacagtgag catgctagtg attcagattt agaattggtg
    88021 cgtaaagcta ttggtaatcc agctaagtct aagacgataa ccttaacagt tcgcaagctt
    88081 acaacaggag ttaatgttcc agagtggaca ggggtatttt tcctttcaaa cacagaaagt
    88141 cctacatctt atctgcaggc agcgttccgt gcacagacac cttttaacca tgcagagctt
    88201 ggaattaaga aaaactgcta catctttgat tttgcacctg accgtgcttt aaaaattatg
    88261 agtggaagtg tcggactaac tagcaagaag ggaaaggtta atagttcaga gcaaaagaaa
    88321 aaactagagc gcatgctaaa tttcttacct atccttggta aacaggggaa tgtgatgaaa
    88381 gaatttagcg ttgaccgaat gcttacggca ctgaagaagg cttatgcaga aaaagctgta
    88441 cggactggct ttgaagacag ctctctttac aatgacaacc tattaaattt agaccaagct
    88501 gatcttacca aatttgaaga ccttaaaaaa attgttggct caagtaaacc aaccaaagtg
    88561 aaagacttca ttgtttcaga taacggtatg agtgaagagg agtatgaaaa agcttcgagg
    88621 gcagaaaaga aaccaaaacg tcaacgtacc aaagaggaac aggaagcaat agatagggca
    88681 aagaggcttc gagagcagcg aaataaaatg atttccattt tgaggggcgt ttctattcgc
    88741 atacctatga tgatttatgg gatggacatt gatattaaag atgacgttac tattgagatg
    88801 tttcttaatt tggttgatga ggcttcatgg aatgagttca tgccagaggg gttaagtaaa
    88861 gggcgattca gagagtttat tgagtactat gatgcagacg tttttgtgga ggcaggacgc
    88921 ataatccgta gacgtgcaaa gtcttatgat gagttagatg ttattgaacg tactaggaaa
    88981 ataggtgaat tatttagcac ttttaaaaat ccagacaagg aaaccgtatt gactccatgg
    89041 cgagttgtta atatgcacct tggtaacact atcggtggac tttccttctt tgatgaagaa
    89101 taccaaaatt ctacggagaa cggtcaacca atcgtgcgat ggaggaaaac tgactgtaca
    89161 gatgatattt ttaaggaaaa tagaaagatt cttgagataa actcaaaaac agggctatat
    89221 cctttatatg cagcaacgag tatgtactat gttcagctcc ttaaacaaag cgatattaat
    89281 gctggaaggg tagattcaga ggcaatatgg gaaaaagtat tatcagagca aatttttgtc
    89341 atttctaaaa ctccaatggc taagacgata acgaagagga ctttgattgg ttataacgca
    89401 tggaaggtaa atgttgaata ctcaagtgaa ttagttacga gtatgaaacg ttcaatcaat
    89461 gacggtttaa cgaatttgaa aggagtttat aaaaacgtga aatttgatgt gataattggt
    89521 aacccacctt atcaggagaa agatggaggt tcaggagcta gtgctacacc gctatataat
    89581 ctatttgtag aaacctctgt taagttatca gaacgctatg tttcgatgat tactccttcg
    89641 aagtggtttg caggtggtaa agggttagat aagtaccgtg actttatgct taacagctct
    89701 agcttgaagg tgatggtgga tatagtaaat gggaaagaaa tattcccaaa caccagtatt
    89761 ggtggcggtg ttagctattt cttgtgggat aagaaatata atggattgac acagtatact
    89821 aatcaacatg atggtgtatc aaatacacaa gagcgaaaaa tgaacgagtt tccagtgttt
    89881 gtgcgatata atgaagccat ttctgcaatt cacaaaattg gggaacacgc tagtgttggt
    89941 gactttgtta tatcacgtaa cccatttggg cttccaacga aaattcgagg ggaagaagtg
    90001 caggattcca gaaattcaat aaaagtaatc tctagtggtg gggtaggctt tgttccactg
    90061 gaagatatca ctaaaggaca ggatatggtt ggaaagtata aagtcattag tagctcactg
    90121 actagcgaac atgcaggtga accgaacaaa aatggtatgt ttaaggtgat ttctactaac
    90181 agagttatta aacctaatga agtagttaca gattcatacc tagtgctatt ttctgctgat
    90241 accgaaaccg aagcaattaa ttatctgaag tatttacgaa cacgttttta cagattttta
    90301 ttacttcaag cagtgacatc tattcaccta tccaaagata agttcatgtt cataccagta
    90361 caagatttta cctcaggttc agacattaac tggaatgtag gtattgaaga agttgatatg
    90421 cagttgttca agaaatattc tttcgatgca agtgagatat tgtttattga ccaaacaatc
    90481 gtcccgattc ttcacgagga atattactaa gagaacaagc taacaaatga ggcttagaac
    90541 cctgttttct tgattaattg ccccacttta aatcaagatt taactgtcta ttatcaacag
    90601 gtcaaggtaa aataaaggat gttagcaagt aaagagattg atttgagtct acatcgaaca
    90661 agggaataat ccaataaaaa atgatttaga atatcaaaat aacaaaaaag aggactacct
    90721 gtattagtcc tcttttttga ccagattttg accagtctat tttacattct aatatattca
    90781 tatgagctaa ttttatgatt aaatggtaag tttttccttg tttgttttag tttaaactag
    90841 tgtgtaattc aaaaatctat atggaagggt ctgtggggta atacttaaat aaaggctagg
    90901 aacctgataa catcaaggtt cctagccttt ttataataaa atgaagcgaa aataatttct
    90961 tttaaagagc cgagattatc agctatataa gagtgaattt gatgcaaaaa acagagccga
    91021 aacagtcttg gtgttcgtag ctctgcttat atgtttcgaa tttaagacaa agagttggca
    91081 aaagatgttg ataaggaaga taagataact gtgttatata aactaggtaa ctaactgtaa
    91141 caagctaatt ttaagagatt cttattagaa gacgtttagg aatataacta agaaaatgat
    91201 tatacaggta attgtcattt caataatgtt ttctaatttt cgcgtctttg ttttaagaaa
    91261 aaggccagaa tcagttggaa aaaagttcgt acgatagtga agaggggcaa aatttcctac
    91321 taatattccc actaacaaga gataaaacgg ccaggttggt gtgattcctc tataaaaaaa
    91381 tgcccatgct accgaaatcc catagattaa caactgaaca atttttacaa tgaaaaaatt
    91441 gttctgccat tactcaaagt ctcttcctcc ttgtatcgtt tatttgtttc attttatcat
    91501 tatgataggc gcttgaacaa tccattttgt attttattga gtactcttgg ataaactacc
    91561 agcgattatc atatttattt atgttactgt aagccatcat ataaaagtaa atgagcagat
    91621 catagaaata taaaaaagaa ctaaaattga tctaaattat gtgcagcttg actacgtacc
    91681 aatctatatt acttactaga ttggtcgtta atctattcgg atcgaatgag caaaatattt
    91741 ttgtgaatgt ccatccttga ttatgattcc aaaaagaatc attgggaggc tgtggcgtaa
    91801 atattatact ataagccaga aatacctatc attctgaact tttttattta ggaactttca
    91861 tctcaaggct ttttcaatta atttgtaccc ctgttttttg gataagatca tgtgcattga
    91921 ttttttctat ctctacgttc atctcctact taatgcctat ctggctcctg agggcttctt
    91981 tttaaggcgt cgtcatagtc ttggctgagg atttcttggt aatctgaggg aatggcttcc
    92041 caagtgagca ggcgaacgtt catgacgtgt tttcctttgt gtttgattac agcatggttt
    92101 ttctcttttt ctacctctcc agcgtgaaaa gacagccatg taccatggcc aaagatatca
    92161 ttacataccc aacgttcgat ggaattgtcc acgtatccta cagggagtgt ggtatagccg
    92221 atttgtggtt tcaaaaaagg attgaatcga tcgatcgttt catttttgta ttgataattg
    92281 ataagaaaaa gatagaccaa acaaaagacg agcagaaaga aagatagtgt ctttttgagt
    92341 gagaagggtt gttttgatga ataagatttc ttgttaacaa gaggttcatc tggcaatgtt
    92401 ggttctattg attcggtagc tgattcaata gaaggaaaat caatcggcag acctaaagta
    92461 tgatgtaaaa gtgacagcat ttcaaagtct ggcattgtac gagaattttc ccaactagaa
    92521 atcgttttat cggaaacacc aattttttcg cctaattctt tttgcgtaag cttacaattt
    92581 ctgcggtaag ttcgtatttt ttctccggtg ttcatcttct tctcctttcg attctacagt
    92641 atatagattt attctacatg acctatacac ttgatagata cgtttttttg atgaaaaacg
    92701 gtatgatttt atcaaagaat catttaagta agggagagtg gtgataatca aaaaaaagtt
    92761 cacagtttta ctcacaatca tagtgaccgg tatcatgagt ggttttgcct tggttagtat
    92821 aaataaacag gtactctatc ggacaaatga atttttccat caaacagata cttatactcc
    92881 gattcgattg ccacaacatt ttattgggca agaagaatat gagcagctaa tcatggtatt
    92941 tgaaaatgtc tcatcagaaa ctgagctttc ttatatgaaa aaaacagtaa atgaatccaa
    93001 tgaagtagat acatcttgga acttcaagat acagccaaag cttgaaatga cattgtatta
    93061 tcaaggggat gtcaaatctt ctcacgagaa ggtaccctat tctaatacct cctttcgcgt
    93121 aacgtccatt gaagaatcga tcaaaataaa agattttgaa ggtgaatttt tcttgatgac
    93181 gagagaaaaa gaagcctatg aacgggtcat ttcactattc actgatcgat tcaatcaagc
    93241 atttcacact gattatgcca ctaatatttt tgaagacttt gaaaatagct attcgtattc
    93301 ggttatttca aatacagacg tatataatta tcgagtgtat ttaactattg gattgattct
    93361 tttattcctt ttgttatcat cctttttctt attgatgaat aaagaaatca gtttattgtt
    93421 gaataatgac ttttcattac atcaagtatt gtggtgttta ttggggaaaa agaaaatcat
    93481 tattacattc ataattgcag gaatcattgg tggttttatt tttatgtatt ataaggagca
    93541 atttctttat ttgttccaga tgtacgtttt cttgttcagc ggaatatatg gtatctcttt
    93601 gatttctctt ttattagttg aaaaaatcgc ttcgttaaga gaagcgttca actatatcca
    93661 atacattctt tttacatttg gattgttgtt ttctcttctt ttgaccgttg ccaatgtcga
    93721 attagcaact atcgtttttt cttcttcaca gttagctgtt tcccatgaac caccaaaaga
    93781 aatcgctggt gaggactatc atgtatttta tccagtaacc atcgggaaaa accacgtgga
    93841 ttttatttat tccaatcgtt ttgcatcagc agcagatcag gaattatatg aaactttgaa
    93901 taaaaacgga agtatattag tcaatgtatc agattacttg aatgaagaaa atgaacagtt
    93961 tggcagaggg ataaaaataa atctgaatta tcttaagaaa tttcctttga ttgatgtctc
    94021 tggaaggttg atccaaataa ccgaaaaaga aacgcaccct gttatattga tccctgaacg
    94081 atatagacat acagatttaa aaaatgacct ggcgcaaata acagaatatt atcaagaaat
    94141 cagtgaaaaa gaaccgaaat ttctatttat aaaaaacaat caacccattt atacatttat
    94201 tccttctatc ccctggatcg aacattatcc ggttgttgaa atactgacat tgaaaaacag
    94261 tatgtatttg gaaagaaata ttctcagcgg agaaatctat ccaccgttaa agatcaagat
    94321 aggctctttg tcgaaagaaa ggttatttga gctgattgaa gaaagtcagt tacgtgataa
    94381 cttgcagtta tcatttccgt atactcagac tgaagagata gctgtcaaag tgttaagcag
    94441 atcatttcat tacttgatac agatattttt actcactttc ttttctttct tcttgttgag
    94501 ctatgtcatg ttatgcatat attttgtcta caattgtcgg aaaatcgcta tctttcgttc
    94561 aagtggttat tcgctctttg aaacgtataa agatttcttc atgatgaacc tcatcaaatg
    94621 gggaacgaca agtgtaatct tcctttttct tatagaaaga gagcctaaat atctttttaa
    94681 tatttttttc tttagcttca ttgattttat tctttcagtt gtttttattt tgtctacaga
    94741 aaagaaaagt cagttattgc tgatgaatgg aggttaacaa ttggagccgt tgatagtgat
    94801 aaaaggtgcg aaaaaaatca ttcgaaacaa aacgattctt catttggatc gtttcactgc
    94861 ggatgctggg gatcttgtga ctgttgttgg agaaagtgga gcaggtaaaa gtacgttatt
    94921 gaatatatta ggattgaatg atcagttcag ttcaggacaa ttctatttgt tcgatcaaga
    94981 gacgaaacaa ttaactggga gagagaagcg cttgataaaa agaaatacca tatcttttct
    95041 ttttcaagat tttgggttga ttgaatatga aacaatcgat tttaatttag atattggatt
    95101 gaagttttcg aatttaaatg tttcagataa gcgaacagca aagtatgagg cattgaaaaa
    95161 agtaaatata aacaagaagc taagtacgcc tatctacaca ttatctggtg gtgagaagca
    95221 aagaatcgcc tgtgcgagag tcttattgaa gaatagcaaa atcattttag ccgatgaacc
    95281 gactgggtca ttggataaaa gaaataagga taaagtagtt gaaatcttat cgcaacaagc
    95341 ttcccaaggt acgttagtta tcgtagtcac gcatgatcca tatctgacca aaataggaaa
    95401 caagaagatc atgctttaaa aatcaaaaag gaaaggatgt cgttttatga aaaaagcagt
    95461 tattatttgt gcactaggga taggttttgt tggaggaaac gctatgtcat ctgaagtgga
    95521 agcaaattca gttcacggtg aaatctatta caaatcttta aagccaggag agattcattt
    95581 tgatgctaaa ggtaatatta ttaagtcaaa tttaccagta gaccgggaaa tttctagaac
    95641 agcaattaat catagctctg gaagatgggt ttattatagt gatacaactt gtacgagaaa
    95701 aacaggtcat tctaaccact atagtcgtgt ctataatcgt cacggtgcaa aagcgaaagt
    95761 tggaaactct attcgatcag caaatgcaac aaaaggagta tgggcctatg caagtgcgac
    95821 aggaaataga actgacacat tctcatgttg gtacaatcca accggttggt attaagtatc
    95881 caaaagttta tataaaatag aaaaaacata taatgaaaca gcgttaaaag ttatttttgg
    95941 tagttttaat atattcattt ttagttgtat aaaaatatat cataataaaa acaacaaaaa
    96001 aatgtctgga aaatcgaaca taaaagtgtc tgatttgaat atcccagcag cggaagaaga
    96061 aaaacaaaat cgataacatt tgttctaaga attagttacg ttaaatacgg aacgcaagat
    96121 agacttgaaa aacggtaaca aaagaagtag tatattaagg tgtgatgtgc tacttgacat
    96181 ttattctgct gagcgaactt tctggattgt gtagccttat atctattcag gacgtatcga
    96241 gcagattagt aaaggtgttc ttgatgattt tcatcttgaa cacctttgtt tttagcaatt
    96301 cgcaaaaaac gaaaagtagg agaattgata aatgaaaaaa agatttttag cacttgccat
    96361 cgtactaggc actggcttat tgtcaggctg tacgaatgcc ggtgaaaaaa cagccgttag
    96421 ttataaaggc ggtacaatca gcgaacaaga agtaatggat agcttgaaaa aaatgcaagg
    96481 agcagattcc gctgtgcaac agttgatcgt ttatcaagta tttgaagata aatatggaga
    96541 tgacgtatca accaaagaaa tcgattctca atatgatcaa acaaagaaac aattgggtga
    96601 ttcatttgat tcacaattga aatctgcagg ttacacagaa caaacattca aagacagtat
    96661 caaacaaagt ctagcctttc aagaaggtct aaagaaacat atcaaattga ccgatgaaga
    96721 tttaaaaacg gcttgggaat ctttccatcc agaagtggaa gctcaaatta tccaagtagc
    96781 aagtgaagat gatgcaaaag atgtgaagaa agctgctgat aagggagacg atttctctaa
    96841 attagccaaa gacaagtcaa ctgatactac gacaaaagaa gatggcggaa aagtgaaatt
    96901 tgattccact actacaacgg ttccggcaga agtcaaagaa gcagccttta agttgaaaga
    96961 tggtcaagtt tctgatgtga tcacttctac caatgcttca acttatacta cggaatatta
    97021 tgtggttaaa atggtgaaaa accaaaacaa aggcaacgac atggataaat acaaaaaaga
    97081 attgaaagaa attgcaacag acacaaaatt aagtgacagt accttccaga ataaagtaat
    97141 tggcgaagta ttgaaagacg ctaatgtaaa aatcaaagac aaagactttg aaaatgtttt
    97201 gagtacattc acttcagatt ctagtacagc aagtagtaaa taagcggtat aaataaaaaa
    97261 tatgaactat ttaaatcaat aaaactgttc atctaaatct ttttattaga actaaatcaa
    97321 cagtagttta attactactt gatttagttc tttttatttt aaaaattttt tttacttaga
    97381 atccagcgac cctagatatt tttctgtata atcttaaata aagaaaacaa tatcaaaaaa
    97441 tgcacgtaga agtagataaa tggagtggtt ttgcaaattt cttttatttc tagaagttat
    97501 tcacgtatac ggatttgttt ttctcacaaa taaaaaggca ggaagtacaa tggatcattt
    97561 gtatataaaa tatattcatc aattttccgt tttggtgtta ggcacactaa ttatagcggg
    97621 gattgtcgca tttattattc aaggccgtga catattaaca gtacatcaag agtttttcag
    97681 ttatgcattt ggtattcctc tgatcgctat aaggtctgat aacaaaaagt ggaagaaacg
    97741 ctattacatt ctcttgctat ttttgtgttt ttatctgcca cctaagattt ttactttatt
    97801 aggtatacaa tgcctatcat tttcttttat ttcctatatc attgttttaa ttttcctcag
    97861 tttcatagta tggatgtttt atcttgtcaa aaaataaatg aatgtttcat gaacagtact
    97921 tcatcacagc ctaatttttt tctttatgct atcgttatat taaagaaatc aatcagaagg
    97981 gaaagaaagt gatgaaaaaa gttttattag tggtaaaccc cagttcaggc ggtgaacaag
    98041 caaaggaatt tgagcaatta gcgatagcaa aattggaatc ggtgtttgat gaagtggtcg
    98101 tcttgcatac aaaaaaagca ggggatgcaa aaaactttac tcgcgaagcg gctacggaag
    98161 ggtatcatag tgtgtttgtc atgggcggag atggaacagt caacgaagga atcagtggaa
    98221 tcgctgaaca agaacatcgg ccaaatttcg gatttttccc attgggtacg gtgaatgact
    98281 tggctcgagc attagggata ccgctagaac ctgaggaagc gatcaatcat ttttcgattg
    98341 aatcagtcaa gccattggat attggaaaaa taaatgacga ctattttatg aatgtcgtcg
    98401 caattggctc tatccctgaa tcaatcaatg atgtagatgc ggagaagaag acgaaatttg
    98461 gaaaactagc ttatttcatg tcaggaatca aacagttagc ttccacacaa tcctactcgt
    98521 ttcacgtaga agttgatgga aagaaggaag aaattgagag cagtaccttg ctgataggac
    98581 taactaactc agtcggcggt tttgaaacat tacttccaaa tgcaaaagtg gatgatggta
    98641 agctccattt ggtttattta aaagattctt ctttgatcga tacgcttaaa acattgccag
    98701 acctattaaa aggagtagat gaatctacga aaaatctagc ctaccttact tgtgagcaat
    98761 tagttgtgtc attagctgat gaggaagaat tgacgacgaa tgttgatgga gatgaagggg
    98821 ataaattacc tgtgacaatc aaagtattgc cctcacattt acaggtttat tgttaaaatg
    98881 gaggttgtga ccgaggagtt ggcgggagaa caccgcttgt tcgggataag ggactgtgac
    98941 aagacttttg tcacagcctt ttttttgtac aaaaaagaaa tttacaccta atagaaaaat
    99001 ttttccataa aaatacatat tttaaatatg aaagtacaat tggaaataga ttaaaacgat
    99061 aaaataaaat tgtcaaaacg tcagagagga tggtggagaa tgaatcaatg tgtaaaaaag
    99121 ctgattgcgt cgattttgtt tgtcttccct ctcttgatgg tgacatccgt ttttgccgat
    99181 gtagagaaaa caaacgaatc aacgcaatca gagaatcaaa gttttgacaa gactactttt
    99241 tcagaagaat cgattacttc tgaaactaca gaatctcaaa gtgaggcttc tactaataaa
    99301 aggcaagaag aaaataagac aagtgagacc tcagaagtag ctgaacaaac gtctgatagc
    99361 agtgaagcgg cactggcaag agctgtttca gcggatgggt acagcgaagc tgccacaaca
    99421 gaagaactgg cgcagcttct cgcagacgaa tcagtaacta agatccgact gattcagcct
    99481 ttgactttag acagggaatt agagatcaaa cgagatatcg ttattgattt tggtggattc
    99541 gctcacaatt tcggcacaca ccatatttat atcaatgaga tacctcagtc gatcgagttc
    99601 cagaatttta aaggaacagc tgcacatcca ggtggattga caccaaatat cgatggaaat
    99661 gccattatca ttgcttatat gaccgatttt tggggaagca aatatcattt tacgggagaa
    99721 ataaaattta ccgggacact tgatttgtat gatgggtcca aattaggact gatttacgct
    99781 cctcgtgcaa ctgtcacatt agatggtgtt tccggtgtgt tggatgtcca accagtgaag
    99841 gaaggactga atgccgctcc gggtaaagcc tatttttgta gaagctatca attgaatgtg
    99901 atcaatggta gtcaacttta tggaccgtat ctagggaaat tctacggttt tctagattca
    99961 ggagatgaga ctggtagtgg aaaaacagcg ccaggaatcc atatcttaag cggttcaaag
   100021 gtctctcttg attatgatcg ggcagatggc gttagcgatg aaggagaggc agtcgatacg
   100081 ctacctggta atgtcatgtt tgaagtcagt ggttcgggaa gcgaattttc ggtaaataca
   100141 aagatcaata ttaccaatga caacaatcgc ggaatcatcc aaatgagagg ttcaggatcg
   100201 aaagtcactg tatcgaatgg tgggaaaatc accatcaata cagcaactac gggcggattt
   100261 cgcttgcaag gagattctag tcaaatccat gtatcaagtg gtggacaaat ctcggtcaaa
   100321 atggctggag atgacgatca acccgggaac aatgggatgc gttttgtagg aaaaggcctt
   100381 tctttgatcg tagaaggagc cggatcagtt atcgacatcg ataagcagag tgggcgttcc
   100441 agcgcagttc gttttgagaa tggtacgcaa aagctgacag taaccaatgg aggctcattg
   100501 agggtaagaa atacaggtga tggcaaatct tacgtgaaca gactcaatca aggaaatcaa
   100561 gcgatccaat tttatgacgc ttctggtttt ctagaaagtc caggttcagc tgattttaca
   100621 gtcactggag aaaaatcaaa tatcgatata cgcgcagatt ccggagcaac tgtagataca
   100681 actggagata ttgatttaaa ttttacggca ggtgaaaaaa cttatttagt catggtcggg
   100741 aaaacagggg aagataagac cggcatcatc agtggggatg tgttgaatgt ggacttagaa
   100801 tctcctacct attttgattt ccaaaacaaa cggattggaa gcgagaccaa tggcataggc
   100861 ggctgggtat tccaaggaaa tggagattct tctttaaaga tcgcccattc agaaatcgct
   100921 ttatggcgaa aaacaggcgc aacattcgat aactttgaaa aagacccgga ttatttttct
   100981 gatatgacag acttatcgat caatgggacc gacttaggca atttcgtatc aagccctagt
   101041 gcaggtttaa caaatgaatt tgctcagaca ggtgccggaa tgaaaaatta taatcgaatc
   101101 agtgccaata atcagctccc gatgattgaa tccttaagag tgccaacgaa tgcagataaa
   101161 aaaatctatg ggcatgtcgt tgttcccgaa ggtgtcgagg caaagccaag agatgcttgg
   101221 acaggcgaag tagaagtgac tttacgtatt acttacgcag atacgacgaa atcatctgta
   101281 gaaattactg ctctcacgca aggacaaaca gatgaaaatg aaggggcagg atataaccca
   101341 tggggagaag gcgaacaagg cggcttgttc gaagttcaag tacccaatga tgagagatta
   101401 aaaacggagg atcaagtgca agttgttgct gctaaaaaag taagaggtgg ccaagaagtg
   101461 acagaactgg actctgccaa aacgacagtc gatgtgattc ctcctgaacc tgctaattta
   101521 agtaccacat tgatcaatgc agcttctcgc acgatcacag gtacaggtga agcaggagcc
   101581 ttggtttcat tgaaaaaaaa tcaagctgtt ttgtcagaaa caactattga tgatacaggg
   101641 gaatttgttc tttctatccc agaaaatcaa ctttttgcag gagatgtatt agaaattgta
   101701 ttaaacgacc aagcaggaga agctactgct aagggtgtgc agaacaagcc aagtaccaac
   101761 gatgaaattg ggaatcacaa tccaagtgat acgccagttg tttatcatga tgccccgcct
   101821 tttgcacctg ctacgaagat cgtagtagaa ggtggtctct catttcttgc cccttccaaa
   101881 ctcgattttg gtcagatcaa agcaactggt ttgacacaag aagcatttgg ccaaatggat
   101941 atacaggaaa aattatggat ttatgatcag cgagaaacga aaaatccgtg gatcttaacg
   102001 ataaaattat ctcagccttt cacaaatgat gcaggatttt ctatgcagga tgtcctatat
   102061 ttcaagaaag gagaggagta tcaattagtg aatgaagaag aactggaaat tgtcagagga
   102121 caaaattcaa cgaatgtgca agcagattat tcagaatatt taaataacgg tcgggcgttt
   102181 aaacttgtct taaccaaaga aaatcagata gctggtaatt actcagcaga gataacatgg
   102241 acattagcag atgcgccgac agaataaaga tcaaggagga tgattgatga atcgaatatg
   102301 gaataaaagt catcgaaaca actgctcttt acttatgatc cttctccttg gattcatcct
   102361 ttggcagaca cctgtccatg cctccgaatt caattttgcg gtagattttg aattaccggc
   102421 taatcagatt gataagaaca aaacatatat aaatgtaagg atggagcctg ggaaaacaca
   102481 ggaaatcccc tacacggtct ttaaccgaac agataaatca gtaacagttg agacattgat
   102541 ccactccgct acgacgaatt caaacggtgt gatcgaatat ggagaatcaa aaagtaaatt
   102601 tgatgaaaca ttaagttatg atatgaaaaa cttagcaaaa acagtgggag aaataactgt
   102661 tcctcctcaa agtgcggtca ctgagacact ttcactgaaa gcgccagaaa aagagctggc
   102721 tggtgtggtc gcaggaggga tcacgtttca agaaaaaaaa gagaacgttt ctaacaaaag
   102781 tacagttggt gtcgtcaatc agttttctca agtgaaagca atcttgattt gaaatagcga
   102841 aaaagagtct tccccagatt tgaaattaaa aaaagcttat gcggatcaaa gcgatggaag
   102901 aaatgtgatt aaggcgaatc ttcaaaatcc aaatgcttct tatatgttcg gcttgactac
   102961 atcggttgaa atctacaaaa aagaaacaaa agagccttac ctttcaataa aaaaagaaaa
   103021 aatagatgta gcacccaata caaattttga tttacttgtc ccattagaag gaaaaaaatt
   103081 agctccggga cattatcaag cggttgtgaa gggtgcttgg aaagaaaaac gctggaatct
   103141 ccataccgat tttgaaataa ctgatgatgc agcggaccaa ttgaatgaaa aggatattga
   103201 tttaaaaaat cagccagaaa catttgactg gcgatggctg atacttgttg gagtcattct
   103261 tattggctta tttgctggat tatttatttt aaaagaaaga aggaaaaaga aatgaaaaaa
   103321 acaattgcat taagtaccgt tctagctgga agtctattat tatgtacaca aagtgttttt
   103381 gctgagaata agagctcagc cactacagaa ggaacgattt ctgtgaccaa accagatgct
   103441 gcaaatcctg aagacgttgt tccagttcct cctgttgatc caaatgatcc tgatactcct
   103501 tttacacctg acgaaccaaa tcagggaaca tccggattac tgacgattga ccaagctcca
   103561 gatcttgatt ttggaacaat caagttaggt acagcaaaaa cagtatatgc tgcattacaa
   103621 agcggaacgg acagtactgg agcacaaaca caagtacaga atttcgtaca agtaacggat
   103681 aaaagcggaa attatgccgg ttggaaatta tcagtcaaac gaacagaatt tattggtaca
   103741 acatctgata cgaataaact aactggttca aaggtgaaat tcaaaaacgc cgtgattcga
   103801 aatagcgcaa ctaatagcag tggaatgcca tctaccgttt ctggaactgg cgctgaagga
   103861 atcgaaatcc cagcagatca ggcagtagat ctagtaactg caggagcaaa tgaagggatt
   103921 ggcacatgga tttattcatt aggagagaat gtggaacaag ggagacaatc agtggaatta
   103981 tttgttcctg tatccaatta tgctgtagac aactacgttt caacattcac atggtcgtta
   104041 acagatgctc ctacagaaga ggaagcgtaa aatcatatca acgacttcag ggagtggagc
   104101 cgattcaagg cccactccct gaaatctgct atgcttacgt ctcagctctt attcatcaac
   104161 tcgaagcagt tttttggaag tcatggaaac gttcctttgt cttttcaaag atctttcgac
   104221 caacgagtaa ggagtcaccg ttgaaaaatt ctaacacata atgagcagaa tcaattttct
   104281 gcaattgcga taagttgata cagtaagatt ttaaaagtaa aaagtaagca tacttttcta
   104341 actctgtctt caattgtttt aaagaagtat tcactaattt atcttctgta gttgttttga
   104401 ccataacttg gtttttcaaa cctttgatac tttcaatata taaaatttcc cgaggataca
   104461 ggacgagact tccacctttt tgatcaataa agattttatc gacatttacg atctgctgtt
   104521 ctttccaatt gatctgttct agcacttgac gaatttgttc agataaattc ctgtcttttc
   104581 tgatatatcc aatcggaagg attttccgat tgatgatctc tactgcaaaa ttcgtataag
   104641 cggtgaaaaa aacaatatta ctatgtgcat tttttttacg tatttgttcg gcgacatcaa
   104701 tacctgtgag tgattgcttc aagtcgatat cgataaagaa aacatcgtga ttatcaatag
   104761 tgcccaactg gatcaactga ttgatttgag agatagaagt gagctgcacg atattctcga
   104821 tatgatgatt gaccaattct ctgatgatcc attcgctgtg aaactggtta tcttctatga
   104881 taaaatactt tttcatatgc aggctcctat taaaaaaata tgtgtacatt ttgaaacaaa
   104941 acaatggagg aataagatgg tcgcaacagt gacactttat ttgaccttta ctttgatttt
   105001 agatttaggt atctatttat tcttttcgaa acaactgcta gtaaaaaaca gctttggttg
   105061 tatagctttg atggtggtga cacttttact tcctatccct aaagtgagct ttccttacct
   105121 aattggctta ttattgatgt ttctttttta ttttactacg aaaaacctgt ttatcagctg
   105181 tttgatcagt aatctttttt ttgctatcac tggactcagc ttttttctgg tttttgatct
   105241 gatggattat ttaggaaaga gacatcttgg aacagcaagt ttttttgcac tacttatcgc
   105301 atttattttc tatctattag taaaaagtat agacaaacag acgagatttc tcaacttgct
   105361 ttttacttat ccaactgaac actattttgg aggtatttgt attttattaa gctggggcgt
   105421 gatttacttg gtattgggaa gtgttcactt ccgctcatct aattatctgc ttctatctct
   105481 tttgtcgata gtcatcagtt ttttttcttt gtttttttcc attatgttga tcagtttcca
   105541 agtaaaagaa agacaacatc aggaatcgct tcaactgtat caaataaatg aagaatatta
   105601 ccatcatcta gaggaattca aacatgatta taaaagtcta ctgttttcat taaaaattac
   105661 tcttcaggaa aataaaaaag aaacgttgga atttttagaa atattagaag atcattctgc
   105721 agctattttt gaaaaaccgc aaatacaaca gctaacaaat attgtatccc cagctgtcag
   105781 gggtgtcttt ttaaaatttc tagaaaaagc agaatcggag aaaatcccga tccaagtagt
   105841 tattcctgtc gaagtgaaaa caatcccgat tgatctggtt gtttttattc gctgtttatc
   105901 tatttttatt tctaacgcat tcgatcatcg tgtagccgat cagagtccga ttacgatcaa
   105961 tctgctggaa gaaaaagagg gatcacgttt tagtatagcg aacaaggcaa atccaacgaa
   106021 tttgacgcta tcggagatgg tcaaaagagg aaaaacctct aaaaaaaatg gcgggttagg
   106081 tctatacagt gcgaaaaaaa tgttggatgt ttacgaaaat gcagaactaa aaatcgaatt
   106141 ttcaaaacag aatcactatt tttttgtaga aatgtatctg gcatctagaa agagcaaatc
   106201 agcctactga cttactgtca aaggataagt ttgaggaaag tctacacgga gatagagaca
   106261 acaacacagc atattcaaaa gaaacagaag cgtgatgacc gttgtcaccc ttctgtttct
   106321 tttgctatgt agttaaacaa agtagttgac acttccgcta cttagtatta gtacgaaagt
   106381 atacttcatg atactaagta gataagaagt gaaaagcgga acccacgatc gtcaaaatgc
   106441 taactgcttt gcttacacca gataaaggga agagcaatat cgcttatttt aggcgtggag
   106501 aagcaagcaa atccctacga tcacaaaaaa aatgctgacc cagcagttaa gagagttaga
   106561 acaagatgaa agtatccatc gaaaagccta taaccaagtc ccgcctaaag tagagtactc
   106621 gctcaccgaa gaaggaaaat cattaagaga gattctagta gcgttgtctg tttgggaaga
   106681 agaacgtatc gaaaaacaaa aagcctcaag ggaagaagac acgctactgc atacacatgg
   106741 tggctaccta aattattgat tttctatgac atttatttta aataaaagaa aacaggagtt
   106801 tttttaaaag catcatctat tttttatgta aaaaaatggt atgattaatc aagtaagaag
   106861 tgattggaag aaggcaagca aatgaatagt atggaaaaag tcaaccagtt tagagatgaa
   106921 cgtaattggc gacaatttca taacgaaaaa gatttggcta tctctatttc tttggaagca
   106981 tctgaattgt tagaactttt tcaatggaaa acgccggaag aagtaaaaga aacacaatta
   107041 gaacgaatca aagaagaact ggcagatgta ttgatctatt catacatgat ggcagacaac
   107101 cttcacctgg atctagatga gatcattgaa gaaaaattga tcaaaaataa tttgaaatat
   107161 cctgtagaaa aaagcgcagg tgtacgaaaa aaatacacag agttgtagaa atgtgtcatt
   107221 cggctgttgg aaagagcaaa agaaaaacag taaaatgagt ctggagggag agaaaatgaa
   107281 aaaaaaagga aaagcaaaaa gatggctagt caatatcctc ttgttcctct tgttattagt
   107341 aggactagct ttgattttca atgaacagat caaggattat tttgtcagag agacaggaga
   107401 taaatatgct atagcgaatg taacaaaaga agatctgaaa aagaataacg ataaagatgt
   107461 cagttttgac tttgatgcgg tagaaccaat gacgacagaa ggggtcatga ggtcgcaaat
   107521 gagaggaaca gatctaccag tgattgctag tatcgcagtc ccttcagttt caatcaattt
   107581 accggttttc aaaggcttgg ataatacgtc actactttac ggagcaggaa cattatctcc
   107641 agatcaagaa atgggaaaag gaaattatgc cttagcaagc catcgtgcaa cgaaccctga
   107701 attgctgttt acaccgctag aaaatttaga gatgggtgcc aagatctatt tgacagattt
   107761 agaaaatgtg tatacataca aaacattttt taaagaaaaa gttgctccta cagataccca
   107821 attactgaat gaagtcgagg gaaaagaaat tgtcacacta attacttgtg gcgacatgga
   107881 cgccgtcacg cgactagttg tacaaggaga actggaaagt gttacatcga taaaagatgc
   107941 gacagatgat atgagatctg ctttcaatct agagacaaaa acattttagg atactgggac
   108001 ataagtcgtt acagattaaa aacagccaaa ggatatgaat cgataaggaa aaaccaattt
   108061 gctgaaaaaa agagaaacgc aaagaggtgc atctctgatt tggttgtttt ctagatagac
   108121 ttgtgttcca gtttttttat tttttatatg aaaaggtttg cataaataaa aattcgatgg
   108181 tatgatgatt ttgaataaga aatggattgt tactgtacgg caggcaaaac cagaattcag
   108241 ctaagaaaca gtaggcgaat tctaggtttt tttatttttc ttgagagggc gaagcaaaat
   108301 gaaaattgat aaaattttga ataacaatgt cgtcatttcg aaaaatggat tcggggaaga
   108361 agtcgtttgt atgggaaaag gactagcttt tcaaaaaaag attggggacg agatttcgcc
   108421 agaagcggtc caaaaagaat ttgttttaag agattctttt gctaaaaacc aattccagca
   108481 gctgatggct gatattccgg cagaggagat cgaatgggtc aaacaagtag tcgaactggc
   108541 tgaagataaa ctaaaagttg aattttcgcc taatatttat ctgacattga ccgatcatct
   108601 tcattatgcg atcacacgag caaaagaaaa tatccaactg cctaatccat tattatttga
   108661 aacaaaaaaa ttttatccga aagaatatca agcagcgaaa gaggctcttt tgttcgtgaa
   108721 acaaaagacg ggtgtggaac tttctgagga tgaagccggt tttattgcct ttcattttgt
   108781 gaatagccaa caaggaaacg aagacatgca agtgacgatg accgctacca caatggtaag
   108841 agatatactg agtatcatca gtaaattctt cggcatcgtg ttcgatgaag aatctttgaa
   108901 ttatcagcgt atcattactc atctgcagtt ttttgcccag cgttatctca aaggggaagg
   108961 atctgacgag caagatgaat ttctctacgc attagttcaa ggaaagtatc caaaagcgtt
   109021 tcattgtgtc gaacggatca atgagtatct tcgacaaacg caaaaacagg aaatggggat
   109081 cgcagagcag atttatttaa cgattcatat tcaaagagta gtaagtgaga aaaaaagcat
   109141 ccaatcataa ggattgttac tgtatggcag gcaaaacctg gattgaaaaa ataggttcac
   109201 gaatgtttgt gactgttttt ttcaatctgg gtttttattt tttaa
//
LOCUS       DAZULR010000002        92530 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.002, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000002 DAZULR010000000
VERSION     DAZULR010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 92530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 92530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..92530
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.002"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(80..277)
                     /locus_tag="ACG8ZV_000100"
     CDS             complement(80..277)
                     /locus_tag="ACG8ZV_000100"
                     /inference="COORDINATES: protein motif:HMM:NF016526.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HFS4995474.1"
                     /translation="MLLRFLFSFCCALYTLRIFTGGVHLNSNILCYFMSVVIVIVAYQ
                     CMFIFRNVDFIILGLMFEFFW"
     gene            complement(423..1301)
                     /locus_tag="ACG8ZV_000101"
     CDS             complement(423..1301)
                     /locus_tag="ACG8ZV_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFS4995475.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(1340..2458)
                     /locus_tag="ACG8ZV_000102"
     CDS             complement(1340..2458)
                     /locus_tag="ACG8ZV_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 172 protein"
                     /protein_id="HFS4995476.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(2455..4554)
                     /locus_tag="ACG8ZV_000103"
     CDS             complement(2455..4554)
                     /locus_tag="ACG8ZV_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HFS4995477.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(4605..5426)
                     /locus_tag="ACG8ZV_000104"
     CDS             complement(4605..5426)
                     /locus_tag="ACG8ZV_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFS4995478.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(5423..6232)
                     /locus_tag="ACG8ZV_000105"
     CDS             complement(5423..6232)
                     /locus_tag="ACG8ZV_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFS4995479.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(6253..6747)
                     /locus_tag="ACG8ZV_000106"
     CDS             complement(6253..6747)
                     /locus_tag="ACG8ZV_000106"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFS4995480.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(6759..7259)
                     /locus_tag="ACG8ZV_000107"
     CDS             complement(6759..7259)
                     /locus_tag="ACG8ZV_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFS4995481.1"
                     /translation="MIKPMFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLS
                     SIQLLTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITK
                     TFLEKEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVN
                     EEEDFF"
     gene            complement(7324..10020)
                     /locus_tag="ACG8ZV_000108"
     CDS             complement(7324..10020)
                     /locus_tag="ACG8ZV_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFS4995482.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            complement(10448..11521)
                     /locus_tag="ACG8ZV_000109"
     CDS             complement(10448..11521)
                     /locus_tag="ACG8ZV_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFS4995483.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            complement(11518..12345)
                     /locus_tag="ACG8ZV_000110"
     CDS             complement(11518..12345)
                     /locus_tag="ACG8ZV_000110"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4995484.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(12346..13152)
                     /locus_tag="ACG8ZV_000111"
     CDS             complement(12346..13152)
                     /locus_tag="ACG8ZV_000111"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4995485.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(13164..14249)
                     /locus_tag="ACG8ZV_000112"
     CDS             complement(13164..14249)
                     /locus_tag="ACG8ZV_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4995486.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(14266..14808)
                     /locus_tag="ACG8ZV_000113"
     CDS             complement(14266..14808)
                     /locus_tag="ACG8ZV_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFS4995487.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            15066..16055
                     /locus_tag="ACG8ZV_000114"
     CDS             15066..16055
                     /locus_tag="ACG8ZV_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HFS4995488.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            16052..16789
                     /locus_tag="ACG8ZV_000115"
     CDS             16052..16789
                     /locus_tag="ACG8ZV_000115"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HFS4995489.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            16786..17337
                     /gene="coaC"
                     /locus_tag="ACG8ZV_000116"
     CDS             16786..17337
                     /gene="coaC"
                     /locus_tag="ACG8ZV_000116"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HFS4995490.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            17353..17985
                     /locus_tag="ACG8ZV_000117"
     CDS             17353..17985
                     /locus_tag="ACG8ZV_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFS4995491.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            18070..18717
                     /locus_tag="ACG8ZV_000118"
     CDS             18070..18717
                     /locus_tag="ACG8ZV_000118"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding oxidoreductase"
                     /protein_id="HFS4995492.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            18722..19705
                     /locus_tag="ACG8ZV_000119"
     CDS             18722..19705
                     /locus_tag="ACG8ZV_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HFS4995493.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(20108..21622)
                     /locus_tag="ACG8ZV_000120"
     CDS             complement(20108..21622)
                     /locus_tag="ACG8ZV_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HFS4995494.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            21760..22566
                     /locus_tag="ACG8ZV_000121"
     CDS             21760..22566
                     /locus_tag="ACG8ZV_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995495.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            complement(22741..23310)
                     /locus_tag="ACG8ZV_000122"
     CDS             complement(22741..23310)
                     /locus_tag="ACG8ZV_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4995496.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(23393..25453)
                     /locus_tag="ACG8ZV_000123"
     CDS             complement(23393..25453)
                     /locus_tag="ACG8ZV_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HFS4995497.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            complement(25730..27208)
                     /locus_tag="ACG8ZV_000124"
     CDS             complement(25730..27208)
                     /locus_tag="ACG8ZV_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4995498.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            complement(27506..28441)
                     /gene="murB"
                     /locus_tag="ACG8ZV_000125"
     CDS             complement(27506..28441)
                     /gene="murB"
                     /locus_tag="ACG8ZV_000125"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HFS4995499.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(28514..29434)
                     /locus_tag="ACG8ZV_000126"
     CDS             complement(28514..29434)
                     /locus_tag="ACG8ZV_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFS4995500.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            29547..30299
                     /locus_tag="ACG8ZV_000127"
     CDS             29547..30299
                     /locus_tag="ACG8ZV_000127"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HFS4995501.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            31163..31696
                     /locus_tag="ACG8ZV_000128"
     CDS             31163..31696
                     /locus_tag="ACG8ZV_000128"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HFS4995502.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(32186..32710)
                     /locus_tag="ACG8ZV_000129"
     CDS             complement(32186..32710)
                     /locus_tag="ACG8ZV_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HFS4995503.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(32703..33176)
                     /gene="tsaE"
                     /locus_tag="ACG8ZV_000130"
     CDS             complement(32703..33176)
                     /gene="tsaE"
                     /locus_tag="ACG8ZV_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HFS4995504.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(33299..34279)
                     /gene="pta"
                     /locus_tag="ACG8ZV_000131"
     CDS             complement(33299..34279)
                     /gene="pta"
                     /locus_tag="ACG8ZV_000131"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HFS4995505.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(34432..35112)
                     /locus_tag="ACG8ZV_000132"
     CDS             complement(34432..35112)
                     /locus_tag="ACG8ZV_000132"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HFS4995506.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            35238..36107
                     /locus_tag="ACG8ZV_000133"
     CDS             35238..36107
                     /locus_tag="ACG8ZV_000133"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFS4995507.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            36133..36648
                     /locus_tag="ACG8ZV_000134"
     CDS             36133..36648
                     /locus_tag="ACG8ZV_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related/scramblase family protein"
                     /protein_id="HFS4995508.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(36695..37258)
                     /locus_tag="ACG8ZV_000135"
     CDS             complement(36695..37258)
                     /locus_tag="ACG8ZV_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4995509.1"
                     /translation="MIRFARKEDAPEIAPLILVILKDMELPFLKQTGEQKTLEILEEA
                     ITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKYQLDASTRLFI
                     DKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLSVDEKNPKAKK
                     LYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(37313..37492)
                     /locus_tag="ACG8ZV_000136"
     CDS             complement(37313..37492)
                     /locus_tag="ACG8ZV_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995510.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(37569..38078)
                     /locus_tag="ACG8ZV_000137"
     CDS             complement(37569..38078)
                     /locus_tag="ACG8ZV_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995511.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(38174..38554)
                     /locus_tag="ACG8ZV_000138"
     CDS             complement(38174..38554)
                     /locus_tag="ACG8ZV_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFS4995512.1"
                     /translation="MNLTTIHPIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            38884..39633
                     /gene="pnuC"
                     /locus_tag="ACG8ZV_000139"
     CDS             38884..39633
                     /gene="pnuC"
                     /locus_tag="ACG8ZV_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HFS4995513.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKLTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(39817..41094)
                     /locus_tag="ACG8ZV_000140"
     CDS             complement(39817..41094)
                     /locus_tag="ACG8ZV_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995514.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(41173..41817)
                     /gene="pcp"
                     /locus_tag="ACG8ZV_000141"
     CDS             complement(41173..41817)
                     /gene="pcp"
                     /locus_tag="ACG8ZV_000141"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HFS4995515.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(42016..42960)
                     /locus_tag="ACG8ZV_000142"
     CDS             complement(42016..42960)
                     /locus_tag="ACG8ZV_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HFS4995516.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(42962..43648)
                     /locus_tag="ACG8ZV_000143"
     CDS             complement(42962..43648)
                     /locus_tag="ACG8ZV_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HFS4995517.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            44121..44441
                     /locus_tag="ACG8ZV_000144"
     CDS             44121..44441
                     /locus_tag="ACG8ZV_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HFS4995518.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGLLLISIIGIKI
                     TSGH"
     gene            44602..45507
                     /locus_tag="ACG8ZV_000145"
     CDS             44602..45507
                     /locus_tag="ACG8ZV_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4995519.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSEGTIRIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVKQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDQAARTILTDAGYPLEDPDKIKLLKKNEELLGTVIQLLSAENVHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            45504..46277
                     /locus_tag="ACG8ZV_000146"
     CDS             45504..46277
                     /locus_tag="ACG8ZV_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4995520.1"
                     /translation="MTLLIKQELFKLIKKKSTAVLSVLLVALLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMESQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSIYLYLLAIIVTVLMKLILFPSISFTEKISTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIALFLALGYLVFKRKNV"
     gene            complement(46454..47878)
                     /locus_tag="ACG8ZV_000147"
     CDS             complement(46454..47878)
                     /locus_tag="ACG8ZV_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="basic amino acid/polyamine antiporter"
                     /protein_id="HFS4995521.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNVASIVMSTIFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFINNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGFLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            48089..48535
                     /gene="nrdI"
                     /locus_tag="ACG8ZV_000148"
     CDS             48089..48535
                     /gene="nrdI"
                     /locus_tag="ACG8ZV_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HFS4995522.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEYEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQRFGFPFLADYELRGTPSDVTRVYQILAEKNK"
     gene            complement(48605..50587)
                     /locus_tag="ACG8ZV_000149"
     CDS             complement(48605..50587)
                     /locus_tag="ACG8ZV_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose PTS transporter subunit IIA"
                     /protein_id="HFS4995523.1"
                     /translation="MAKNELTLEELAKQIYQGAGGMGNVESIVHCMTRVRMKVINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQEMVDLAGVKLGEKLPSASATTAS
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAGTWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALATGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKAVPQASA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVISSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAADK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(50601..51497)
                     /gene="murQ"
                     /locus_tag="ACG8ZV_000150"
     CDS             complement(50601..51497)
                     /gene="murQ"
                     /locus_tag="ACG8ZV_000150"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016835 - carbon-oxygen lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA];
                     GO_process: GO:0046348 - amino sugar catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HFS4995524.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELPSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISEHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEAAQAKLAEANGFVKGTL"
     gene            complement(51500..52561)
                     /locus_tag="ACG8ZV_000151"
     CDS             complement(51500..52561)
                     /locus_tag="ACG8ZV_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HFS4995525.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQNRLIELGSEAKKNKLELMVDISGEALKRAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPNDIDELKEAAADFSQIEAWHNYYPRLETGLDKEWYQEK
                     NQWLKTQGFLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSEHVQEQFASFQKEQTVLLHTEPVDEVFYEYILGKHTNRQDDARDVIRSADARF
                     REIPPIPVRNTAKRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(52773..53300)
                     /locus_tag="ACG8ZV_000152"
     CDS             complement(52773..53300)
                     /locus_tag="ACG8ZV_000152"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFS4995526.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQALAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVVDRLNLPMTADERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECMEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELISYE"
     gene            complement(53367..54869)
                     /gene="eat(A)"
                     /locus_tag="ACG8ZV_000153"
     CDS             complement(53367..54869)
                     /gene="eat(A)"
                     /locus_tag="ACG8ZV_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection-like protein
                     Eat(A)"
                     /protein_id="HFS4995527.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQAFVYFPQQTKDKERLTYYVLNEIMDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEIAKNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKKVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDALTMNSQVSHHKRLLSVENLQLGYENLLFEPVHF
                     TIEPHQRMAISGPNGAGKSSIIHYLLGTFNGKVVGEKSQPKHLTISYVRQNYEDNRGT
                     LAEFAKKNRVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYI
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLEKI"
     gene            complement(55127..56248)
                     /locus_tag="ACG8ZV_000154"
     CDS             complement(55127..56248)
                     /locus_tag="ACG8ZV_000154"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFS4995528.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALGGTWRTIDGMDLLFRQRKISYLLTNWQGKNTAVIESAQVLGLDLLDKP
                     TDQTIRLASSYALGELIKDTLLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTRKLHLDRRNVLVSKVKVIIAADVTNPYTGQQGAAWQFGRQKGGTDTTLAFLD
                     KQAEKIAQQIKDVWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFELVSQITGLEKQI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDRELEGLFDFLPIV
                     LSIQLGPIDLEEAMEHRQTLEKTEILGQTLSRFFNILPK"
     gene            56374..57315
                     /locus_tag="ACG8ZV_000155"
     CDS             56374..57315
                     /locus_tag="ACG8ZV_000155"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HFS4995529.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVVLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNKHVDLIVALTKANQLDDMFRSIQSIITENTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEAKLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAEGM
                     VRTIVSEFASIAAKEGITLDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAVWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(57458..58354)
                     /locus_tag="ACG8ZV_000156"
     CDS             complement(57458..58354)
                     /locus_tag="ACG8ZV_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HFS4995530.1"
                     /translation="MNKNDVLLIAKNKSLYFFPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMDFSSSEPKTDLFFGATNNGRKERAEKYKQEFTKR
                     GVTTNYFILPLRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYQFYHSENIFLLQERDLDELPEFLHTPFQPIPSELLEFFDAENWAKR
                     FFTTDSAIYEQYEYDLSSVKNK"
     gene            58636..59976
                     /locus_tag="ACG8ZV_000157"
     CDS             58636..59976
                     /locus_tag="ACG8ZV_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFS4995531.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGIILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHAADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFAAYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLIIFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLTLRKGTLW
                     DKGISFFALAVLWLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            60171..60614
                     /locus_tag="ACG8ZV_000158"
     CDS             60171..60614
                     /locus_tag="ACG8ZV_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HFS4995532.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINAMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILTSKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(60876..62294)
                     /gene="nhaC"
                     /locus_tag="ACG8ZV_000159"
     CDS             complement(60876..62294)
                     /gene="nhaC"
                     /locus_tag="ACG8ZV_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HFS4995533.1"
                     /translation="MEKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKKYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDILEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPKLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(62698..63921)
                     /locus_tag="ACG8ZV_000160"
     CDS             complement(62698..63921)
                     /locus_tag="ACG8ZV_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFS4995534.1"
                     /translation="MTTTLSTNQLKDLIQYRLPEYQALALAIHDHPEVSNYEFYSSAA
                     LIKQLEKEGFWVEKEVAGHRTGFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDEIGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDAALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAALSTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSEKGLASIAIAAELLANTALDLLREPKLLEKIKQE
                     HQEIVARKKQEGATF"
     gene            complement(63953..64792)
                     /locus_tag="ACG8ZV_000161"
     CDS             complement(63953..64792)
                     /locus_tag="ACG8ZV_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFS4995535.1"
                     /translation="MKKIIRFAVITFVAIIWLAGCSQGKAATTEKKETTVKLGIIGED
                     TDVWDDVKDRLKKENIHLEYVKFTDYNQPNAALADGSIDLNSFQHQFFLDNYNEEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENKKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDEHARPYVNIIVARKEDEDNKTYQKIVDAYQTEETAKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(64809..65489)
                     /locus_tag="ACG8ZV_000162"
     CDS             complement(64809..65489)
                     /locus_tag="ACG8ZV_000162"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HFS4995536.1"
                     /translation="MTEFFKTYLPNVYLIPDEFIEATKQTLYMSFWTAFIGGIIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILVLVFLSQFISN
                     QLIKKVTH"
     gene            complement(65491..66564)
                     /locus_tag="ACG8ZV_000163"
     CDS             complement(65491..66564)
                     /locus_tag="ACG8ZV_000163"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HFS4995537.1"
                     /translation="MIELRDISVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEAGK
                     IIEKGSSIQIFSHPEEELTKDFIRTATHLDQALETISAHAAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRQKALDYLIKS
                     GVKVTILQKNELDNRIKVIEGGN"
     misc_binding    complement(66623..66861)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(66904..67137)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(67214..67885)
                     /locus_tag="ACG8ZV_000164"
     CDS             complement(67214..67885)
                     /locus_tag="ACG8ZV_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFS4995538.1"
                     /translation="MKGAIFDLDGLLVDTERTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVQAAGSPEKVQEVRAKREEYFYQQLTSGAIQLKPYAKEILTDLKERHM
                     KLGIATTTVTKRATDILDHFQLADYFDTFTFGDEVSENKPSPVPYLTALERTGLEALS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYSVEEKEKLNLLAEGKDLRTVIEMLD
                     KKTEK"
     gene            complement(67963..70611)
                     /gene="mgtA"
                     /locus_tag="ACG8ZV_000165"
     CDS             complement(67963..70611)
                     /gene="mgtA"
                     /locus_tag="ACG8ZV_000165"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015444 - P-type magnesium transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HFS4995539.1"
                     /translation="MEKKKDTQKIYAAFAGKTKQELFELFHASPNGLSEEQIERSRET
                     YGENAISYGKKTPFIIEILKAYITPFTLVLIALGIISFITEYVLAAPGDKDLFGVAII
                     FTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGEYTEIPMEEIVCGDLVRLS
                     AGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSYENLVFMGSNV
                     ISGSAEGIIVSVGNDTLFGHVAETLSEKPIQSSFELGIHKTSMLLIKFMSLMAPAVIV
                     INGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGTVIKNLNAIQN
                     FGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQTGLKNLLDVAI
                     IDEAAETLDTDTINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGAIEEMLNISKF
                     IDLGGTVAPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFSVKDESDMVLI
                     GYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLEINELITGEKI
                     SEMNDHELAQVAEEHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGINDAPAMKVADI
                     GISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKATASSNFGNMFS
                     VLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKWNASSIGKFMV
                     YFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQQVIFIALFHAGWFVESLWTQT
                     LVLHALRTPKIPFIQSNATFAMLVITTLGIIVGSVLPFTGFGAELGLMPLPGNYWLWL
                     FITVVAYLALVTAVKKIYIRRFQELL"
     regulatory      complement(70954..71128)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as
                     a genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
     gene            71301..71738
                     /gene="ndk"
                     /locus_tag="ACG8ZV_000166"
     CDS             71301..71738
                     /gene="ndk"
                     /locus_tag="ACG8ZV_000166"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HFS4995540.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFATMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKGADAVPGTIR
                     GDYALPGTENIIHASDSRDAATKEIARFFPPFDTNKPSEKAAK"
     gene            complement(71760..72626)
                     /locus_tag="ACG8ZV_000167"
     CDS             complement(71760..72626)
                     /locus_tag="ACG8ZV_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4995541.1"
                     /translation="MYDGELIKKLRVNKKLTQTQLAEGICSKTSLVGIETNSVKKVSF
                     GTLKSFLERMNMTLAEYEWIRNQLDEPKKLKKKRRMLDRIQEDSFDPYKEIANNRRHY
                     KKTEDLYYLVLNLHMSKKTEVSETEFEFLRYECRIIEEYLMQVPEYGQFEVSILADFP
                     WIFSDRFIENNYLKIKKRMRRIAQLNNHEQYLFTFLTNLTLFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKSENHQEFFAVIEYTLGKNQRNSL
                     EKKLLAIAKPSS"
     gene            complement(72860..74938)
                     /locus_tag="ACG8ZV_000168"
     CDS             complement(72860..74938)
                     /locus_tag="ACG8ZV_000168"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFS4995542.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVSKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPATLGQTEGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTIL
                     YPVTGTNAEQ"
     gene            75431..76648
                     /locus_tag="ACG8ZV_000169"
     CDS             75431..76648
                     /locus_tag="ACG8ZV_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFS4995543.1"
                     /translation="MPYILALDVSMGHSYSVLYKDDTCLFEDEIEHTQRGFHALLEEI
                     QHLPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEENTLRSWKTDKSD
                     AHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMDLHNCLQLTFPEL
                     EQFFSNRLTPYALTLIRLFPHPDFVLASTRTKIKNKLINETREKISANRAEQKADQII
                     HYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQKKALATQMIKKAEASPCFLLYQTFP
                     GIGALTAALLLGELGDITRFKTHKQLNAFVGIDIRRYHSGKYTGQDRINKRGNPKARK
                     IIFFTIRNMIRQQRAAPNHIVDYYYKLKKQPIPKKDKVATVACMNKLLKCMHAMVRAH
                     TEYDYAYAVSVDH"
     gene            complement(77107..77730)
                     /locus_tag="ACG8ZV_000170"
     CDS             complement(77107..77730)
                     /locus_tag="ACG8ZV_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995544.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWEEYKLTANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLVVLLLTHDGDKVARLKNGKVVTAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     ASSQKNESTELSPSDSGSGQTITGNEENQASIITNESSEGQYQTYGQ"
     gene            complement(77886..79283)
                     /locus_tag="ACG8ZV_000171"
     CDS             complement(77886..79283)
                     /locus_tag="ACG8ZV_000171"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFS4995545.1"
                     /translation="MKRYQFPKNFWWGSAASGPQTEGRISGDGKGENIFDYWYKNEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HHYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFQLFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKAYHEMDQSGVI
                     GIILNLTPSYPRDESNPEDVKAARIADAFFNRSFLDPAVKGEFPSELIERIKELDLMP
                     EIHPDDLTIIKENTVDLLGINYYQPRRIKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEKGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDRNGFEA"
     gene            complement(79305..80276)
                     /locus_tag="ACG8ZV_000172"
     CDS             complement(79305..80276)
                     /locus_tag="ACG8ZV_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFS4995546.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMEKISEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISNRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHAIDGLIVFLSEEEWSGFEMLTKMSIPVVALNCPGGPAGIDTIVVNDR
                     ESVAKVIAHHGGQGHKTIGFIAAAQTDYVARERLAGAKEAVQKDPSIHLEIFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            complement(80283..82584)
                     /locus_tag="ACG8ZV_000173"
                     /pseudo
     CDS             complement(80283..82584)
                     /locus_tag="ACG8ZV_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308318.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 3 N-terminal
                     domain-containing protein"
     gene            complement(82586..83911)
                     /locus_tag="ACG8ZV_000174"
     CDS             complement(82586..83911)
                     /locus_tag="ACG8ZV_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFS4995547.1"
                     /translation="MKVVDRLSEKMLPIVSKMSSQRHLLAIRDSFIVTMPLVMAASVM
                     VLLNALIFSNATVQRILDLSPLAELASIVNNGTMSILAIIVCYNIGWNLATHYIQTGV
                     IDDPSFSPVHAGILSTAVMFILMSLSSTVTLMDGNTAEATGVFLQSLTSSSGLATAMI
                     AALVSTELFIKLAKMKSFKIRMPEGVPPAVAASFNSLVPEIVVILFFSVVVFTLNHTT
                     GLNVPQLIELAIQTPLKAFVLSVPGILFLQFFSDFLWVFGMHGSSILAPIRQAPLLQS
                     IQENMDAFSVGKEIPNIITEPFTNAFGLIGGGGCILPLVIAILWASKRQEQRSIAKFG
                     LTTCLFNITEPIMFGLPVVMNPIYMIPCAIIPSINLVIAYAATSLGIISKTVAAAPWI
                     TPPVIQSFIATGGDIRAAVLTVILIILDVFLFLPFVLAANKAKLAEGGY"
     gene            84142..84567
                     /locus_tag="ACG8ZV_000175"
     CDS             84142..84567
                     /locus_tag="ACG8ZV_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995548.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DITNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGADSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKEATVTFTKIGNYRLKDKDGNIYSL"
     gene            complement(85065..85766)
                     /locus_tag="ACG8ZV_000176"
     CDS             complement(85065..85766)
                     /locus_tag="ACG8ZV_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFS4995549.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDTFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(85782..86222)
                     /locus_tag="ACG8ZV_000177"
     CDS             complement(85782..86222)
                     /locus_tag="ACG8ZV_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HFS4995550.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVLAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFEKLPVETYVGEYL"
     gene            complement(86222..86797)
                     /locus_tag="ACG8ZV_000178"
     CDS             complement(86222..86797)
                     /locus_tag="ACG8ZV_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0009691 - cytokinin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HFS4995551.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            complement(87208..87714)
                     /locus_tag="ACG8ZV_000179"
     CDS             complement(87208..87714)
                     /locus_tag="ACG8ZV_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lyxose/D-mannose family sugar isomerase"
                     /protein_id="HFS4995552.1"
                     /translation="MDYKKRVQQMFLDSGVVLKETELERIEYTDFGLGAIETEGLNLF
                     VYENNERYCGKELVLLPYQTCPEHRHPPRDENEGKKETFRCRKGLVYLYVEGKETKKL
                     SCIIPKGQERYYTAKKEIILHAGDQYTIEQNIKHWFQAGATGAVITEFSSSSDDPSDS
                     FTNPAIYR"
     gene            complement(87725..88237)
                     /locus_tag="ACG8ZV_000180"
                     /pseudo
     CDS             complement(87725..88237)
                     /locus_tag="ACG8ZV_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014566402.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(88376..89077)
                     /locus_tag="ACG8ZV_000181"
     CDS             complement(88376..89077)
                     /locus_tag="ACG8ZV_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFS4995553.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQEILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            complement(89185..90627)
                     /locus_tag="ACG8ZV_000182"
     CDS             complement(89185..90627)
                     /locus_tag="ACG8ZV_000182"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFS4995554.1"
                     /translation="MQSRFSEKFLWGGATAANQLEGAYDRDGKGLSVADAMPGGKQRF
                     AIIGSEEFDWTIDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPN
                     GDEGTPNEAGLEFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYE
                     RFAQTVLERYSSKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVA
                     SSKAVKIGHELRSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGE
                     YPAYTARTHKKYGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSE
                     GNLLGGVKNPFLEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDG
                     TIIDDYRIDYLRRHIEAMANAVADGVDLMGYTPWGCMDLVSASTGEMSKRYGFIYVDL
                     DDEGNGTLNRSKKKSFDWYKEVIASNGVNL"
     gene            complement(90641..92506)
                     /locus_tag="ACG8ZV_000183"
     CDS             complement(90641..92506)
                     /locus_tag="ACG8ZV_000183"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFS4995555.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
BASE COUNT        27068 a        19505 c        16057 g        29900 t
ORIGIN      
        1 tttttttctt gctatctttt tataatcaca actctctata atagaattac gatttatttt
       61 atacggctga aaaaatctat caccaaaaaa attcaaacat taagccaagg attatgaagt
      121 caacatttcg aaaaatgaac atacattggt aagcaactat aactattacc acagacataa
      181 agtaacacaa tatattacta tttaagtgta cgccaccagt gaatatcctc aaggtataca
      241 gcgcacaaca aaaagaaaaa aggaaacgca gaagcatttc ctttcagtga tttaatgaaa
      301 acaacacgat ttgacttaga gcctttttat ttgaattcat tttcgcttta tccaacttca
      361 tttgatcatt tgattactcg gttaaatact tttgacatga gtatcaatga aacattcatt
      421 aattatggtt gcttatttct taccgctttt ctggccaatg ctaatccgcc gattattccg
      481 gcattatcac ctaattcggg cgtaataatg tagctatcaa ttggtggtat ttcaacatat
      541 ccatttataa gctcaacaaa tttatcctga acttttttct tcatgtgttc ttgtttcatt
      601 acaccaccgc caaaaataat tctatctggc gaaaacatca gtgttgtatt gtatgcacat
      661 tgggcaaggt aaaaggcttc aatctgccaa aacgaatcgt cagccaataa attctggcct
      721 tttacaccca accgtttttc aatcgctggt cctgctgcca tcccctctaa acaatcttgg
      781 tggaagggac agtttcctga aaaattgtcc tttggatgtc gcttgatcaa catatgcccc
      841 atttccggat gactgaaccc ttccacgaaa gtcccattga acaaggcacc acctccgata
      901 cctgttccca cagtgaagta tgcaacacct gctaaccctt tgccagaacc agcaacatat
      961 tcaccatagc aagccgcatt gacatctgtt gtccattcaa tcggaatatt gaaatattgc
     1021 tttagcgttc ctacaaaatt gaaattttgc caagcaagtt ttggtgttga tgtgatatga
     1081 ccgaaactcg ttgatttgca ttgaatatca attggaccaa agcagccgac cccgatgcct
     1141 gccaattgtt ccttaaaagg tttaaaaaaa tcaatgacct gcttcattgt ttcaactgga
     1201 gttgttgtgg gaaaactgac tctttccaaa atcgttaatt cctcagtacc gactgcacag
     1261 acaaatttag tccctccagc ttcaattgcc ccatatatca tcataggttc ctcccttcga
     1321 atatgtgaaa aacacttcat taacgcggca agcgttctcg atcagtgaaa tgacgtttag
     1381 tatttcctga agcttctgtt gaataccagt aagcgacact agcaacatcg tcttgccgct
     1441 caaataagcg aacatcatcg ttgccgattt gttgtaaagt gaccgataaa tcttcggtaa
     1501 aacagatggg gtcttgaaga tgccaacgat aaagaccatg tcgtggcatt gcgtcgtcac
     1561 caaaggcatg aacggcattc aattttcccg tttcaaaacg atctcttgtg gcatctctat
     1621 ttgattggta aggataccct aaaaaggctg ttgaatagtt tttcgcatgt ggacgtccga
     1681 actcatcgta ctcatgaaag gcccacgccc cgccaaaata atcttctgaa cctgttgagg
     1741 ttacggtcgg atactcacta tccccatcaa tgtagaattt aaactcgcct tcgccccacc
     1801 aataacgttc taggcaggta agcgcaaggt aagtacccac gtaatagcct tgacccttta
     1861 atcgatcaat taacttataa tcctcctgta atttggtaat gcgttcccga tgccaatttg
     1921 cgtgaaaata taggctattt tcttccaatt cgtccaccaa agcgtaattt atcgtataaa
     1981 aaaatgagga catatccttc ggatgtaaat tctcgatcgt aattttagcg gatgtttgga
     2041 aaggcatttc gaaataggaa ttaaagcccc ctgtaggatt aaccactatc ggcaacgagt
     2101 tcacctcgca acgctctcca aacccattac aaaagaaatc ccctaaagga ctttcaacag
     2161 cagggctatc cgacccatcc caataaattc ttaagattaa atcacgtaaa acaaaactgc
     2221 caaattctgt tcgatcacga atcgtcatcc acatatgacg aattattccc gttccagtaa
     2281 tatccgcaat cacagtttct tcaccagaag tcagcggaat tgcgccacga cctttgcggc
     2341 ttggtcctag ctcgcttggc aacatcgcag ctttaccttt ctcgcctgtt ggattttcgg
     2401 gagtgattgc tcgactctgg atttttttaa attgggtaat attttttagt atactcatct
     2461 ttttctcctt tgaatgtgaa tcgtttttcc cttttctacg tgaagaattt ttttcgtatc
     2521 acttattttc aatggctttt ctgacaaatt tgaaatactc aactcggatt gcgtacattc
     2581 aatcgaaatg aaggcttgac cgaacttcaa attcttccaa gaaaacgtta aattatcaac
     2641 aggatcaatt tgcaatactc cttttttgaa tttcaatccg aaatattgac tgatcattag
     2701 gctgacaaaa agacccgatg cccagccgca tttgccgcag ccaaagtctc gcacgacttc
     2761 tccttgttga gcctctaagc gatacggcca ccaccaccac gaaccgtcta aatctgccaa
     2821 acaaattagt tcttctaatc gggttacgaa agcttgaggg ttgtgcagct cgctcattaa
     2881 aacagtgata aagccaggaa aagtggcgcc ggattctaat ccccaagtga tgcctttgat
     2941 ttcctcgcta taggttggat tgaaagaact agcagaaaag gccatggtgt tctgatataa
     3001 atgatcttta ttatctaaaa attgataaaa aggcatcaac gtagtgtctg attcttctcc
     3061 atcatgcatc aataaattaa tttttccatc cacaatcaca tcacttaaaa agattaaccc
     3121 ttgctcaaga atcggttttt gatagtgctt cactgaatag gttgttttct cctcatcacc
     3181 gattccctcc aaaaattgct caccaaaagg accatcgata gtcatttgtt tacaaattga
     3241 ttcctttagt ttacaggcaa tgtttttgta tcgcttgcta agactcagtt gttctagggc
     3301 ttcaaaaatt tctgcaagtc caatacaggc cttccaaaga caaagattgc tgccggtatg
     3361 atactttcca agtgcaaagg cgtctgataa ccaaacagat ggaaaaagca ttggttcccc
     3421 tgaccgacgt tgagctaata tgtcctcaat aattcttgaa gcattcagta gaacctgcgg
     3481 acaccgctca aagaattttg tatccccagt atgttcaaaa taaagactag ccagtaacgc
     3541 actggataac gaattactca gagaatgatt gatacctcct gtaaattttg aaccaggaaa
     3601 cttaacgcca tattgatcaa accatagaac cgttttttga cataactccg gttcaaacat
     3661 ggtgaatggc aatgatgcgt aatacatatc cttattccaa attcgattag tagcaggata
     3721 gctgccccaa ttgctgccga cgacctgtcc ctgtcgattc ataccgaaac tagaaaagct
     3781 ttgataaagt gcacgacgat agagatggac aactctatcg tttggcattg acagctgccc
     3841 aaatagctga gcaaaatagt tcaatgtttc cttcagccat ttttcgatat cagattcctg
     3901 aaaagtcatt acttcttcaa aagcatttgg gtccacaaaa gcaatggcga agcttgccac
     3961 ttcctgttgt gcgatcgtgt ccttatttcc tttttgagaa atcaacacat tttgctgatc
     4021 cgaatacttc tcttgatacg aaggcacatc tttcactgaa acttgaaggc tttcgtgtgt
     4081 ttcattcaca atgtaaacct gttgaacaag catacttaaa cgcttattag ccagtatggg
     4141 agcaaaggat actacaatga ccttaaacgt cgaataatga tgaatatatc taggcaaaca
     4201 gtcttgaatc acatcgactt caatacgatg atccgattct gacaaatggt agacaatccc
     4261 gtttacttca acctttaagg ataacgaatt ggtttgagag agctgtttat tgacccaaac
     4321 acctggtttt tcctcagtta gtaaattttc tcgataaaag gtcaacgttt gaatcgtccc
     4381 gcaaacatca aggtttgcta atgtcttttg attacttaca tcgaaggtca atccctttac
     4441 atcaggaata ttccgatagt agctgtattc gtttgaagta gtcacatttc cgtcgtttaa
     4501 ctcagcatta aaaaatgggt gtttgggtga ataaattact tcattaatag tcatcttttc
     4561 cctccttgct aaaaaaactg cagcctagta gctgcagctt cctactatgc gattccaagt
     4621 aatgacaata aaattcccaa gacgaccatt ccaaaaataa ttttgatgac gccgactttt
     4681 ttatctagta atttgaaaca gctcaatgtt accaataacg gtacaattcc tttaaaaata
     4741 ctatcgagga tttcttggac attcattagt tcttcgccct tcattgaaaa gctcaaaacg
     4801 gtattgaatt tgaccatact gatcgtcatt gcacctacca tgatcagacc caagatacta
     4861 gcagcttttg tcagaatttc aattaacccg ttcgcataca gcttttcaat atatttagag
     4921 cctaatgaat agcctaaaac gccgccatag tatcgcatca agtaattagg tatattgaac
     4981 ataactaaaa agataattgg tgccaaaata tttccggcat tggctaagtt gatcgctagt
     5041 cccgcggtaa cgacacgcca aactccccag aacaatgaat cgccaattcc agccaatggt
     5101 cccatcaaac tcgttttgat cgcgttgata ctttccacgt caaaaccagc tttttcagaa
     5161 ttttccttct ccatcgatgc cgcaatcccc atgacaaagg acgcgcaagg aatggtcgtc
     5221 gaaaaatact gtgtatgacg ttccagcgcc gcagctcgat cttcttcact tttgtagaaa
     5281 tgattaatga agggcatcat agaataggcg aaaccaccgc cgcccatcgt caccggattc
     5341 accgaagcat acatagtcat cgagcgccaa aacatcttcc gaaccaattt tttctcatct
     5401 ttagaaattc catcagctaa tttcattgaa agaaatcctc ctcttcttgg tcaagcgttg
     5461 catttacagc agcatcgctt tgaactgcat gaacagatat attttttagt tgtagatctc
     5521 tttgggctat aacaattgca ataatcgttc caactgcggc aattgcaatc aatggtaact
     5581 cgagatacgc cataacaacg gccccaaaga aaaaccacac agcaatattt ttactccaaa
     5641 gcatccgtaa cagcatcgcc atcccaactg ccggcagcag atttccagcg actgttaatc
     5701 cgttcatgat gacctctgga atattatcca agacgctttt gacaacatct gctccaaata
     5761 aaacggcaaa gaatggaata agagcataaa gcgcatagtg gacaaaccac ataaagaagt
     5821 gcagattgat gattcctttt tgatcaccag attttgcaaa tttgaaaaat ttagcagcca
     5881 tcggtccaca tacaaaagaa aaaatcatat tcattaactg taatcctaat actgctagtg
     5941 gaaagacaat gggaataatc gcatccacgt ttcctcccat tttgattgcg aacgctgtag
     6001 ccagcccagc agccaaagaa ggctccgccg tactagagat tccgatattg acgacaccca
     6061 taaagatggc ttctagtgac gccccgacaa tcaaccccgt ctgcaaatcc cccatcaacg
     6121 ctcctgctaa cggagcaaca acaatcggac gactcagcat ggacatcccg aacatttcat
     6181 gtccagcaac tccaataaaa acggccaaag cgactacaaa tgcatcatac ataatttttc
     6241 tccttccttt ttctaaaaat cactcaaaat agagatagct gaacgttttt ccatcgccgg
     6301 tgtaggctga aaaacggtat ctggataaag ttcaactaat tcttttaagt cttgaatttc
     6361 tgacgtcgtt aacatcactt cctttgataa ggttttctta tcttccgatg gcggtgtcat
     6421 tttcccagca ttccccacgt tcattaattc gatttccgtt gggaaagctt tcgcaacttt
     6481 taccgcatct ttgacattag ggactaaaac catcaagcgc atgtccttcg cccgcggatc
     6541 ttttaacaaa tgaatcgcgt catcaactgt tttaataatg actttgacat tcgatggtgc
     6601 agccatcttc aatgtcatct tttgaatatc gttggtagcc gcctcatcgc ttgctactac
     6661 taacccggtt aaatttagac tctttgtcca agtcatcgct acttgtccat gaattaatcg
     6721 ttcatcaatt cgcactgctt taatcatttt tcttcctcct aaaaaaaatc ttcctcttca
     6781 tttactacat gtacctcatc aagaatggtc atctttaatt cctgttggca tttatttacc
     6841 agttcctgaa tatcctcctt tgttaattcc ttggttgcca atactatttc gagcagaatt
     6901 ggcagattaa agccagacaa aatagttaca gcaatctctt tctccaaaaa ggttttggta
     6961 atcttctgat tgacacttcc gccaaataaa tcggtaaaaa caaaaatctg atcctgctcg
     7021 ttcacctggt ttacaaatac attcaactcc tgttcaaaat cacactcatc cacataagca
     7081 ttaatcaccg taatctcttg aaccttcccc gtcagtaatt gaatactgct aagaaagcct
     7141 gaagctaagt gaccgtgagt cgctattaga attttcttca tatggttaat tcctttcttt
     7201 ctgttcactt ttatataagc aattcctgtg ccaactttta aaaacattgg tttaatcacg
     7261 ttaattcaca ttaaaaaaag tgtctaacct aaaaaaaaca gattagacac ttttttagac
     7321 actttatttt tgaatatacg gtcctaataa ttcatagagc agcgaaagct cataagcatt
     7381 gactttaaaa ttatatttca tctccattga ttgaaaaata cttctagaaa cataataaaa
     7441 ttcatcttca tctggtttca aatcataatt cggttcttca gatttttctg tccgagccaa
     7501 gaataaacgt tccatcatca atgccgtatg catatagaga tttagtttta cacggccatt
     7561 taaagtgaaa tgatagtaat tttcatattt agaaatgact gtttccactt cactcatcac
     7621 gatcgttggg ttcagaaagt tcaaacggtc cgcaattcct tccaacgaaa agaattttac
     7681 tagctcctga atcaagcggt taaattctgc cggcttcatt tcaggactca aaatatgctc
     7741 caaattggct gctccatcac cgtctaagat gtcataaaca ttaatattag gaattgaaaa
     7801 ggaacgtgga agatccgaag tcgtgatgac caattttgtc ttgtcaaaat aagtttcatc
     7861 attttggtcg attaattcac gtagttctct gtagtccttc gtgaaaactt cgatggattc
     7921 atccgataaa tgatgacgaa aaacatcttt caatttgtcc gaaatcccca aacccgacat
     7981 acaggaaatg ataatgttgc tactttgaga aaagccttca aagtattgaa cattgattga
     8041 atacttgtct gctgcatcct ccgcaatctg tttaaatggc gcattcatcg tcatcttcaa
     8101 gccaatatca agtgcaatgg aagtcgtcaa attattcaga agaagtaact ccccttttaa
     8161 atcgttcttg atctgtgtgt aaatttgatt taaagagccc atatctacga tcagcactag
     8221 actatctgta ttcacttgcc gtttcacgaa attccttgtc gattcgacaa tctctgacac
     8281 attactctct actggcatat ccaacgcttc aaaaacataa ttgccgcata attgattcac
     8341 tactgcttga atgctgctag ccgtactatc tccgtgagca agcaacaggc ccttcagctc
     8401 gatggattca tctacataat cagataaagt cacgacaata agcagtctta gaaagttctc
     8461 gtccttttct gagagcggtg gtaaatgctc caagaactga ttacataagt aagtcgtccg
     8521 aggtagattt gcagctaatg tacgatttat cccggttaag tctgtcttat agcttgggga
     8581 aatgacatag gatctgctaa taatttctgc aacaggtcca ctcgtcgtca atccgtacgt
     8641 ttttcctaaa acggataccc agacctttct aaacatctga atcatcaatt ttctactcat
     8701 tgataaaaaa gaatccttat caatgtgatg caccaaatgc tgtacttcat tctttatcga
     8761 agaaaaattt tcattgaaat taccttcatt tatcagctga gtaatttttt ccaaaatcga
     8821 atcataatca aacggtttga ttcgatccgt ttttatcttt tgatttttct ttatcaataa
     8881 actagcaatc ggcaagcttt ctacttcgga ttccagcata tttaactgaa tcaagatctc
     8941 atttttccca atcgttaatg gttcttcttg tgttcgacta tacacatccg cacaactgat
     9001 tttaatgata ttcttcagct taccaatatt cccactaaag ggatgagata acattaaaga
     9061 caaggcttct cttgaaacaa taatatcttt ttgtaaaaca tccgcttcat tttgaaaaaa
     9121 taattgaatc agctctaatc gttctcgaat ggggcgatct tcaaaagttg gcaacataac
     9181 actaatttga atacgccgat caaaggtgtc taataaataa ttttcacctt tttccgtcgt
     9241 ggcgaaaata aaacgaacct tagcagaatg ccaatttaca ttttcaccga ctggacgata
     9301 gtttccagta tcaataaata gaaagagctt ttcttgattt tctttcgata ggcgatggac
     9361 ctcatcgaga aaaagatagc cgttgttggc cgttgccaat aaaccatcgg tatccttttc
     9421 agcccccgta aaggccccct tcttgtatcc aaacagtgtt gccgaaagca gttcgggatt
     9481 gtccgcataa tcggcacagt ttaagatagc aaatggtgca tctttttcaa taatttgctc
     9541 atggatagcg tattcaaaaa tttttgtggc taaaaaactt tttccaacac ccgtggctcc
     9601 atttattaat acactgagtc cgttaggcgg atatttgaca gcggctatac atttttgaat
     9661 gacctctctc agacttccgt catgaccaac tacagaatga aaggcttcgt ttatttgctc
     9721 cgtattatct acaaccgcat attcatctaa aggcttccac aaaacaggct ttcccggtaa
     9781 tttctcgacc tttttatctt ccactaatct cgtcaaataa tggctggcat tctgacgaga
     9841 gatacctaga ttcttcgaaa ttttctcggc agtgacagaa gacatattcc ctgttagtcg
     9901 tatcagctca tcaaaaactc gatctttagc gctctttttc attttttcct ccagtttaat
     9961 gtgtctaaaa gcataataaa ctatcggctg caatatgtct attctatatt tgtattccaa
    10021 tttttacttt gaaacacaaa tagtcgaata tttgcctcag atatctgaca aaataattta
    10081 tctaccaatt tagtttttat ctaatatgat ttttatgttt tttcatagct acaaatattg
    10141 aactggattc atatattagt tttattaata gattacagaa gggttaagta tatttgcata
    10201 gtttccaatt actttatcct tctgtaactt tttcaatctt agatttacta gcccgtctcg
    10261 ggccctattt tacaatggtt ttgtccactt ttctctggta gaaaaacgtg gtagaaaaaa
    10321 taaaataaca caaaaaaagc ggcgtttcat ccgcttttgg tagaagattg gaaaactcag
    10381 atagaaaaag gacgattttt agctctttag aacgttgata agtccccatt cttactgagt
    10441 tttgccatta tctcctatac atcttgaatt ctaagaatag gtcattatag atgcctaggt
    10501 atttcgatcc tagatctttg tagacttcaa gatgggagat cgtgtcatca gatggataga
    10561 attgttcgtc cgacgaaatg tcttttggca ataacgcttt tgcttcttca tttggtgtag
    10621 aataaccaat atactctgca ttttgtgccg cattttccgg ttctagcata aagttgatga
    10681 aatcataggc accttcttta tttttcacgg tttttggcat aacgatatta tcaaaccaaa
    10741 gattggatcc ttctggtggg atcacataat gtaaatgttc attttcccac atcatatcgg
    10801 cagcttcgcc agaaaatgtc actgccacgg aggcttcttc attgatcata tacattttga
    10861 tctcatctgc cacgattgct ttgacatttg gtgttaaatg attcaattta tttgctgctt
    10921 ctgtcagctg tgccatattc ttactattca aagaatagcc taaactattc aaagaaagcc
    10981 ccataacttc tcgtgcaccg tcaatcagca tcaaactgtc ttttaattcc ggcttccaca
    11041 aatcatccca atgcttaatt tgatttgcat caaagaattt atcgttatat acgatcccta
    11101 aagttcccca aaaatatgga atcgaatact gattatctgg atcaaaatcc aagtctaaaa
    11161 atcgtggatc aatattattt aatcctttga tcttcgaatg atctaatgga agtactagtt
    11221 tttctttgat cattttttgg atcatatatt cacttggtat agcgatgtcg tagtttgtcc
    11281 caccttgctg gatttttgtg aacatcgctt cattagaatc aaatgtttca taattcactt
    11341 tgtatccata ttctttttca aatttcgtga tcaaactagg atcgatataa tctccccagt
    11401 tatagatggt aagtaccttt gctccactca tgccacttgt tttttcaagt tgacgaacac
    11461 caagcagcag caccgcaata atgatgagaa tacctaaaaa cagagattgt aattttttca
    11521 tcgcagccgt gccaccccct cgcgtactct tctgtttttc ttcagccgtt ttggacggtt
    11581 ttctttacta ataaagtagt atccaatgac caatatcatg gagaacaaga aaactaacgc
    11641 acttagcgca ttgatttcta aactgattcc ttgtcttgca cgagaataga tctctactga
    11701 gagcgtcgta aagccatttc ctgtgacgaa aaatgtaacc gcaaaatcat caagagaata
    11761 ggtaaatgcc ataaaatatc cagctatgat tcctggagaa agataaggca aaatgatatt
    11821 tttgactact tggaaattat tagcaccaag gtctctagcc gcatcgacca ttgaatcgtt
    11881 catttcctgc aattttggca agaccatcaa gacgacgatt ggaatgctga aagcaatatg
    11941 ggaaagcaat acactctgaa aacctaatcc gaatcctagt agtgtaaaga aaatcaagaa
    12001 actagcaccg ataataacat caggagagac taataagatg ttattcatgc tcaacaacgc
    12061 tgtccgtgca cgtcgttttt tcgtgtaata gattcccata gccccaaatg tcccgatgat
    12121 cgtggcgatc aatgcagata agaaagccag catgaacgta ttcaatacga taatgatcaa
    12181 acgtgtatct tcaaaaacag cttcataatt ttcccaagta aatcctgtaa agctgttcat
    12241 cgttcctcct tcattgaagg aataaaaaat cagatagaag atcggtgcat ataagaataa
    12301 aaagacgatc cctaaataaa gatacgacca tttaaatttt ttcatttatg agcgacctcc
    12361 ttttttcttc tcgcctgtca ggagcatcac gatgaacata gcaatgatta aaatcacacc
    12421 gattgtagaa cccatccccc agttttgtgt aaccaagaaa tgctgttcga tagccgttcc
    12481 taaagtgatc acccgatttc cgccaatcag acgagtcagc atgaataaag aaagagaagg
    12541 aataaatact gcttggacac cacttttcac accatttaat gataacggaa aaatcactcg
    12601 tcggaaggtc tcaaagctat tcgcgcctaa atctctacta gcactgatca aagaaggatt
    12661 catctcttcc aatgcattga aaattggcat aatcataaat ggaatctcga tatacgttgc
    12721 cacgaacaga aaactgaagt ctgtgaataa tatctgtttc ggcccgatcc cgataaaatc
    12781 aaagaaatga ttcacgctgc cgtgcacact gaaaatccca ataaatgcgt aagctttaag
    12841 cagcagattc acccatgtag gcaaaataat cagcatcagc cataattgct tgtgcttcag
    12901 ttttgttaaa aaataagcag tcgggtaact gatgatcagc gtgaaaaacg tgatcaaaaa
    12961 tgcataccat acagaattga tcgtcataga aagcgatgtc cccgacgtaa aataagatag
    13021 ataattattc agcgtgaatt gcccattcat atcaaaaaaa gattgataaa tgatcattaa
    13081 tacaggcgcg atcacgaata aaccgagcca caaaatataa gggacggaat agatcctgcg
    13141 cattgttttc attcttgtcc cccctattct tcgtagctgt caagacgtgc atcgaattct
    13201 tcttcagact cgttgaaacg catgacatgg atatcttctg gctcaaaggc caatcctact
    13261 ttgcttcctt ctttagcttt tttcgttgaa tggaccatcc attcattttg ctgttcatca
    13321 taacagatga tttcataatg gacaccacga aacagctgag tatcgaccgt tacgactagt
    13381 tttcctttat ctggtgtcgt gatcgtcaaa tcctctgggc gtaaaacaac ttcaactggt
    13441 tcatttagac gcatcccgcc atcgacacat tcaaattgct taccaacaaa ctcaactaga
    13501 ttatcttcga tcattacacc gtccacgata ttgctctccc caacaaaatc agcaacgaaa
    13561 tgattgattg gctcatcata aatatctacg ggtgtaccac tttggacgat tttcccttta
    13621 ttcatgacaa aaatctcatc actcattgcc aacgcttctt cttggtcatg agtaacaaaa
    13681 ataaacgtga ttcctaatcg ttgttgcaga tcccgcagtt catactgcat atctgtacgt
    13741 agtttcaaat caagcgccga taacggttca tctaatagca atactttcgg ttcatttaca
    13801 attgctcgtg caatcgctac acgctgtctt tgaccaccag acatttcact aatctcccgt
    13861 ttttcgtatc caggaagctg gaccatacgc aaagcatctt ttaccttctt ttcgatatct
    13921 gatttggaca ttttcttgat cttcaatcca aaagcaacgt tatcaaaaac attcatatga
    13981 ggaaaaagtg cataatcttg gaagactgta tttacttgtc gcttattagc tggcaaatca
    14041 ttcaaccgtt tcccttcaaa atagatgtcc ccttctgtag cttcggtgaa tccagctata
    14101 atacgtagga tcgttgtttt accacagccg gaaggaccaa gcagtgtata aaattttcct
    14161 tgttcgatct caaaacttac tttttttaat actgtttcat catcatagcg tttcactact
    14221 tgatcaaatg aaatgattgg tttccccacg tttttacccc ctatattaca aatatgattg
    14281 cgttgcaaca atcaatactt ttgttcgttt tttgagatga ttccttaatt gatgttgttt
    14341 tgtcgcttga taatagatcg actgtcctgc ttttgccaca tagaccgtct ctcctaagct
    14401 taactctaat tccccttcta atacaaaaat aaacgtttca gataatgaag gttcaaacgt
    14461 cttatattct cctgcacctt caaaagtcag caagacaggc tccatttctt tttcattcga
    14521 atcagccacg agccattcca attcataccc gttttcttca tcgaaataaa ccgtatgatc
    14581 ttcttttgaa taaaccactt gcagattcgc tgcttcttga tgaaaaaatt cttctggagt
    14641 cacacctaag acttcaagaa tagaaaagaa tgtttccatt gatggtgaac ttaaatctcg
    14701 ttccaactgg gaaatatacc cttttgacaa atctgtgcgt tcgcctagtt cttcttgtgt
    14761 caaattcttt tggatgcgca aatttcttaa cttctcacca atttccataa tttcctccga
    14821 atcgaagttt tctaatagta aacttcctgt ttactaccac tcgtattagt atacgaaatt
    14881 tattgaaaaa ggcaaccctt tgtaaaattt tttttgctga atatttcttt atcttttgga
    14941 ataaattcta gttgtttgat tctttatttt tcacctaatt tttgtctaaa tttacggaag
    15001 aacaagaata aaagagtagg ctttatggta tgataaaaga aaattttaaa aggagtgtct
    15061 cacgaatgaa cgcttttcga tcttttcagg taataaagga acctgttttc catacagcaa
    15121 tcagtgatct gccatttact gagttggctg aaaatgaagt cttggtaaaa attgcctatt
    15181 ctgatgtcaa ttataaagat gcattggcaa tgagcgagtc tggtcaggtg atacgaacat
    15241 atccgatgac tccagggatt gatttatccg gaactgtcgt ccaaagtaac aatccacgtt
    15301 tttcaaaaga agatcttgta cttgctactg gttttgggct tggcgtcacc catccaggcg
    15361 gttatagcca atatcaaaaa gtaccaggag actggttagt tcctctacca aaaaatatga
    15421 cgctgcgtca agcgatgatc cttggtacag cagggtttac tgctatgttg tgtgtgaacg
    15481 ctttaatccg tcaaggtatg acctccgata aaaaagttgt cgttactggt gcttctggcg
    15541 gtgtaggcag tacagcgata gccctgttac ataaactagg attccagtca atcattgcct
    15601 tttccagaaa agaagagtct gtcacatggc taaaaagtct aggtgctttg caagtcgtac
    15661 gacctgatga atttctgcca gagacaacaa aagctttagg aaaacagcaa atcgactatg
    15721 tcatcgacac agtaggtggc gagcagctaa gcagtcttct tccattgatc tcttataacg
    15781 gtgcagtagc tttatgtggc aatgctgggg gaatcaaact aaacgcgact gtcttgcctt
    15841 ttattctgcg aaacatccag ttgattggaa ttgattctgt caatgtacca atagatcaac
    15901 gtctttcttt atggcaacag atggcggatt tgcagattgc agatgaactg gtcgtccaag
    15961 agattactct ggatcaattg cctgaaacag catctaaact acttgctgga acacaccaag
    16021 gaagaacact agtaaatgta ggtgaccata aatgaagatt ctaatcacag ctggaggaac
    16081 gactgaaaaa atcgatcaag tacgtgctat tacaaatcat tcgacaggac gattagggca
    16141 agcattagct gattatttag ctgccaatcc ggataccaca atcgattacg tgactacgaa
    16201 acaagcactg aaaccgaaaa gacactccaa tataacgatt tatacgatcg aatctgcact
    16261 ggacttattt ttacaattag aagaactaac gaaaaaagaa cactacgatg cgattatcca
    16321 cagtatggca gtcagtgatt ttactcctgc ttttagtttt tcagaagaac agctggcaaa
    16381 aaacctaccc acttcttcaa cgcaagaaga actggacaat tggtttgcgg aaaatgaaca
    16441 gacagatacc actgtttcaa agatctcttc taacaccgag catcttgtgc tcgttttgaa
    16501 gaaaacacca aaaatcattt cttatctacg tgaatggcag ccaaaagcaa aaatcattgg
    16561 tttcaaacta ttagtagatg taccaaagga atctcttctg gcagtcgcaa aaaatagtct
    16621 gataaataac aaaactgatt ttattttcgc aaatgatttg acggaaatcc atggcgagac
    16681 acaccacggc tatctcttat ctaaagatgg aacagtggaa gaagctcaaa gtaaatctga
    16741 gattgctgca ttgattactg agaaaattag actggaggaa tcaaaatgaa aaagatctta
    16801 ctaggcgtta ctggaagtat ttctgcttac aaaagcgctg atcttacaag tcaattcgtc
    16861 aaattaggtg cccaggtaga tgtgattatg tctaaaagca gcacacattt tatcacgcca
    16921 ttaaccttgc aatctctgtc gaagcgcgca gtccatacag acgtcatgca agaatcaaat
    16981 ccgcaggtaa tcaatcatat cgaactagca aaacaagctg acttgtttct catcgcgcct
    17041 gctacagcaa acattatcgg caagctagca aacggcattg cagacgatct tctttcaaca
    17101 gtcgcaatgg cgcttccagt gggaacacca aaattgattg cccctgccat gaacacgaat
    17161 atgtatcaaa acccgatcac tcagcgtaat ctggaaacat tgagatctgt cggctatcag
    17221 gaaattgaac caagagaatc tcttttagct tgtggagatt ttggaaaagg tgccttagct
    17281 gatattcaga cgatcatcga acaggtcatg ctgactctta atgaaagaaa tgcttagaaa
    17341 aaaggagtac ttatgaaaaa tacaaaaaac tttacattaa ctgcgatgtt tttagctatt
    17401 ttgattttat tagctgttac gcctttaggt tttatcccta tcggtccaat caatgcaaca
    17461 accatgcata ttcctgtaat cattgcttcg atcgttttag gaccaagact aggtgctttt
    17521 cttggcggta catttggact gatcagcatg atccgtagca cagttatcca aacacctttg
    17581 tcttttgtct tttctccgtt tatcccagtc atcggaacag aacatggaag ctggaaagcc
    17641 ttgctgatcg cgtttattcc tcgcatcttg attggggtgg ttccttattt cgtttataaa
    17701 ggtctgcgca aactaatgaa acaaaaagca gattccgttt ctttattctt agctggactt
    17761 tccggttcat tgaccaatac gattttagtg atgaatatga tctacttttt attccagcaa
    17821 gattatgcca aagtcatcgg aacaaattta aatgctgttt attcagctat tctagcggtt
    17881 atttttacaa gtggtatacc tgaaggaatc gtcgcaggtc ttgcgactgc agcagtatgc
    17941 aatgtcttgt taagatactt caagcaccct tctcttacta actgatagtc atcgtagccg
    18001 atctctgatt tttttctctt ttggtgttac tattgaatgg aaagatttga cgtcgaaagg
    18061 atgatccaaa tgaaaatttt tgttgtaggt gcaaacggac aaattggccg acacctgata
    18121 aaagatttag ctccaagttc ccatgaaatt tttgcagggg tgagagatgt tgcttcccaa
    18181 acattagtaa aaaaagagaa tgtttcgtat gtctcttttg atttaacttg gtccgtggaa
    18241 aaaatgaccg aagcattcaa aggcatcgat gtattgattt ttgctgccgg ctctcaagga
    18301 aagaatcttc tgcaagtaga cttggatggc gcaatcaaaa cagtgatcgc agctgaaaat
    18361 gcgcatgtct ctcgctatct gatggtcagt gctgtttatg cagatgaacc agcaaaatgg
    18421 cctgagtcca tgacagatta ttatattact aaacattatg cagatgaatg gctgaaacga
    18481 actaacttag attttgtcat tcttcaacca gtcacattga ctaacgatga agaagttact
    18541 tccattcaat taactaagcc taatgagaag gcatcaaaaa cgatcactcg ctctacagtt
    18601 gctgctgtac ttgccgctct agtggaagaa acggatattt ctcgtacgac tctagtactt
    18661 tctgaaggta gcaaagagtt gaatacagca ttccaagaat gggcaaagga ggaatagatc
    18721 catgcgtgcc atttcaatca agcatcctgg ttctgtagat gtattagaac aaattgaagt
    18781 gcctgttcct aaaccaaaac aaggcgaatt actgatcaaa gtccatacag cagctgtcaa
    18841 tcgaacagat attatgaaaa gagaatcagt ctctttgaaa cctccctacc ctattttggg
    18901 agtcgaagta gctggagagg tagttgagaa taaaagtgat atctccactt ttactcctgg
    18961 gacaaaagta tacggattag tcaatctagg tggttatgcc gaatatgctg tgatgcctgc
    19021 cgatcgtgca atccttctcc ctgatacgct agactatgtt tctgctgctg gaatctcaga
    19081 agtttttttg actgcttatc aaacacttta ctggcttgga aaattacaag aaggcgaaac
    19141 tgtcttgatc catgcaggag caagtggtgt gggaacagca gcgatccaat tagctagaca
    19201 gctttctcac gcgaaaatca tcgttactgc aggatcagaa gaaaaactcg ccttttgtaa
    19261 agaacttggt gcagatgaat tgatcaacta taaaaaacaa gactttcaag aagaggtacg
    19321 aaaaatcact gaaggtcggg gagtcgatgt tattttggat ttcatcggcg cttcttactg
    19381 ggaaaagaat ttagcttcta tagccgttga tggacgttgg gtcttgattg gtatgctagg
    19441 tgggaccatc gtgcctgaga tagaccttgg tgtattgatt gggaaacgtg tccaactgct
    19501 tggtacatta ttgacaccta gaagtgatca gtataaagca gagctcgcac aaacttttat
    19561 gcaaaaagct gggccttttc tagaaaatgg caagattcgg ccaatcattg accgtacatt
    19621 ccaattcagc gcagtcaaac aagcgcatga atatatggaa gcaaacaaaa acatcggaaa
    19681 aatcattttg aagataactg aataaaatca tgctgatcaa aaaagaggct gggacagaag
    19741 cgtttaactc caagaaataa gaagaaattc acgaaaattg cttttcaaat ttttgtgaat
    19801 ttcagcttat ttccgaagga atttcttctg cttccgccgt ttatacgtgt ttagagcgtg
    19861 agacaaaagt gttctttact tttgtcccac gctctttttc cgaataaacg gtgttcaaaa
    19921 gcttgcatct gcggtaataa gtccaaccaa gttaaaaaca taagaagctg tttttacttg
    19981 gctgttctta ttacttgatg cagggcagct ttttcacaac ctcttcacta aacagtgttc
    20041 aatcagctga ccctcggtat tagctcaaaa cgctgatttc acaacctctt tttatttacg
    20101 ttctatttca ttcattttcc gaagcaaatc gagctgcttg tatgcccgct tgtcgcccaa
    20161 aaataatgat ctccgcaact gaatttccac cgatccggtt gtttccatgt aagccacctg
    20221 tgacttcacc agcagcatat aaccccctaa ttggctggtt ttctttatct aatacttcag
    20281 tgttcgtatt gattttcaca ccgcccatcg tgtaatggat tcctggtgcg attttgatcg
    20341 cataataatt cggagacgat aagtcatgtt ccatggctgt ggcacggttg aattgagcat
    20401 cttttttctc cgcaacatcc gtattccatc catcaactgt ttttgctagt gtttcttttg
    20461 gtaaatcgat tttttctgct aattcttcca ttgtctttcc agttgtgaca tatccttttt
    20521 ggtcataaaa ttcaatagct gtggcacgat cacgcacgcc ttggtcaaaa atcaaataag
    20581 ctgatttttc aggcaatgct gtaattgctg cagatacttt atcccttgta tccatttcat
    20641 tgacaaatct tttcccctct tgatcgacca agattgctcc ttctccgcga acaacctcac
    20701 caatcaagac cccctcatcc tgctgcacag ttggatgaat ttgtatttta tccatatcaa
    20761 cggtttgtcc acctaatttt tcaatcatgg tgataccatc tccagttgat ccttcttgat
    20821 ttgtcgtaat ataatcagct aaatcgggac gatatttttc aataaattct ttgctggcac
    20881 caaaaccgcc tgtggtaact acgattgctt ttccggtgac ctcttttggt tcttctcctt
    20941 gaacatgtac agtcacttca ttgaccgttt ccccattttt cttaatgtct gtcacatctg
    21001 cgttgacaaa aatagggatt tcccgctcat ggacgttatt caataacccc tccactaagt
    21061 atccaccaat agccgagcca tcagacggac gatgtgtcct cttttcactc atccctccag
    21121 tgatcgttaa gttgtccagt ttgataccgt tttgatctag ccaatcgacc gcatcagcag
    21181 agtgatcgac aaagtatcga agcatttctt tatcattcgt tcctccacca ccttttagcg
    21241 tttcttcata gaaggcatca ttcgagtctt tgattccttc ttctttttga aattttgttt
    21301 ctgaagcatt cataccgctt gatgatttag atgtgtttcc tccggcaaca ggcatctttt
    21361 ccaaaattac tggattcaac ccagcatctt ttgcttcgat agctgctgcc atccctgcac
    21421 caccagctcc aataatcacg acatcataag attctttcat ttcttttgga tctgtatata
    21481 cttgttcaga agcgcctgat gatacttcgg cagattcctt cgtactagaa cttgtctgcg
    21541 ctgtattttt ctgatctgcg ccgcatgcgc tcatagcaag aagtgcaacg gctgttaata
    21601 aaccagcaac taattttttc atttgtatcc cccttttctc cttatactat attaagtgat
    21661 ttttttcaca atatcaactc tgtttttctt taagtcatat agctttggta aacacacgct
    21721 tcttagtata attaaggata tacatgaagg agttatttta tgaatcattt gaaaaccttt
    21781 tttacgaaca gtacaaaaac tgcaggtaga atcacaaacg gaatctatat tttattacgt
    21841 atcatcgtcg ttattatgct agtggatcag gtctggaacc aacactgggg aaatacaatg
    21901 cttttattac tgacattaat tttatttgaa atcccttatt ttctggaaaa gatattaaag
    21961 atacagattc caaatatgct agaaatcatt ttgttatctt ttatttttag ttcaacagtt
    22021 ttaggagagt taagtgattt ttatggctat ttttcaatgt gggatacttt tctacatgca
    22081 ttcagcggat ttttagctgg gggtgtcggc ttttcccttg tttatttgct caataaaaat
    22141 acaaaaacca tgaacttgac tcctttatta ctagcagttg tttccttctg tttttcgatg
    22201 acagttggtg ttatgtggga gtttgtggaa ttttcagcag ataaattact gcaattcgat
    22261 atgcaaaaag atacgatcat ccagcaaatc aatagtgtgg agttaagtaa agacggaaac
    22321 actgtctatc atgttccaga tatcactcgg acaatcattg aaagtcaaaa tgcagatggt
    22381 aaaacagata aaacaatcat ccaaaatggt tacttagacg tgggaatcat ggatactatg
    22441 aaggatttat ttgttaattt tattggagca gttgttttca gtgtatttgg ttacctctat
    22501 agtcgaaacg attaccaaaa atttacgttc atcaagaatt ttattcctaa aaaaatcaaa
    22561 cgataaaaca tgctaaaaaa caagagaagg ggcagtgaca atacttttgt cactgcccct
    22621 tcttttttga atgtatggca tgccattagt tatccgatag tattaactca aaaaagtaag
    22681 atatgaggaa tgactatttc gttttttatc ccaatactga ggacttattt caccatttcg
    22741 ttatttatct aatttactta aaacctgcat aactttttca taatctggat taggtgtgcc
    22801 gtctagattt tcagcaataa aagtaaaacc cattttttta taaagagcaa tcgcctgatg
    22861 gctccatgtc tgtgtgtgaa gatagattgg tccgtccgta tggagggtag gaaattcttg
    22921 caagactctg gcagtcaatg cttttgcgag cccttttcct tggtaatctg gtttcactgc
    22981 taaccaatga aaaaccggat acacttgctc tcttgatttt tttcgccaag cggtacaggt
    23041 tgctactttt tctccttttt ttgtctctac aaaaaacatc cttctttcaa gttcttcagg
    23101 ataaggagca aagttttgtt gaaaatactc aagtgcttca tctgtcgttt gaaattcccc
    23161 aacggaagtc tcaatctccg cccaagcaga ttcatcttct ttttgataaa atcgaaattc
    23221 aaaaccttcc gctaaaggcg tgattggaac attttgttga agtggtcttg tcatccagat
    23281 ttctgcgtaa ggtaacgttt tatctaacat ttttctatcc ctcctcgtct ccattatgcc
    23341 aaataacata tgactcagct acttatttga ctataacaga tagagatata aatcagaacc
    23401 agtcatctgc gtcaaattca tttcgattag cgtataccca tgttcctgcc atacctcgca
    23461 tgaaatctcc taaagcagaa gaaggaatac ctccaccagg tgcgggtgtt cccggactag
    23521 gaagtggtac ttgcggctgc agatgctcat cggtggaatc aatagttgac aagcgttttt
    23581 tcttcgtttc cttctggtca tctgattcct tctgatcttc cgactgttta gcaacaaatt
    23641 ctttttctga ttgttgtttt attttaggct ctaaaatttc attttccaat ccagaaactt
    23701 gtggggccaa atgagcttct tgccttatcg ttttattaga ttctgagatt tttctagata
    23761 ttcttgctaa ctctaggctt cttgtttgtt ttactttccc tgttggagaa actgcatggg
    23821 ccatttgttg ttttttttct gacaagcttt cttcttgtct tttttgttct ttttgatcta
    23881 tctgtttgtt taatggtaaa acatgtaata gtgactgagc atggagttct tggagtgaat
    23941 acgggtcatg ataactatac ataatcgtaa aatcacctgt ttgtttggtc aaataaccat
    24001 cctccaatgg tacttcattg attgtaaccg atacatcctt taacggtacg ggtttaccta
    24061 aggaatttgt tgctgattgg atcaactctt ctttgtttat tttttcgttt ggatgaacaa
    24121 taagatcatg accttctaat gaacgattgt ctggtatata aacataagta aaggtaattt
    24181 cccctcctga ttgcttccta ttattcatca gttctgagtg aagtacttca aggatctccg
    24241 accagtgact ttttctgtct aatccgtttg cttgcatcca atcagaaata gaagtgactt
    24301 tcccattttg ttcataagtc gataaatcta tatttggcac tcgatcagaa aattcagcag
    24361 gtaggcgcaa atcaggaata cgatttacac tactcatatg tgtttctgct tgaagttctt
    24421 tatttgtttg actatctata aaatgagtga tgacagtcga tgaagcagca gatgcttcta
    24481 cataaactac agctgttgtt tctgccacat ttgatgtttt cgagtctata taagttaata
    24541 caacgggata ttctcccgga gttgtagtat ctactgtccc gttcattttg atttcttctt
    24601 tatttcctga agttccatcg ctttttgtta catattcaac aagatcttta ggggcgtaac
    24661 tctctcctgt tcttaagtga agatcttttc ctttgatagc tgtttgatca gcacgaacat
    24721 ggatcacagc agatgcagtc attgttttta aagcaattgg atcaaaatag gacaaggaaa
    24781 tagtagatgt tcctgtatta gtcgtatcca cgatattccc attgtttgaa attactttgg
    24841 acatatctcc ttgtgttcca tctgcgttct tcagcctttc taccagatca gatatcgaaa
    24901 cttttgtccc tgccagaaca tcgattttct ttctttcaaa ctgtgaataa tctttttcat
    24961 atacataaga aacttgtgcg cttccaccgt cctttatatc tgtcaaagca tgattcaaaa
    25021 tatcagtgat ctgttttaac tgatcacctt ttgtaggatc agtcatatcg gaaaagatag
    25081 aaagcggcac actgcttccg gtttccgatg tccataatgt tttgttagga attaaccagt
    25141 agtggtttat cgttggagga taactgactt tattatagga agtcaatgca ggaagtagct
    25201 gttttccatt tgcatcagtg aaagtatgag taatagtgat aggggaatca gtggtctcag
    25261 aaacagaggt acgtacgacc ttgatggttt gtgtcgttgc ctgaacgggt acatgcatat
    25321 agacacctac agataaactg atcagcatcg tgcgcatcat aaacttaacg tagtgttttt
    25381 cagaacacga ccgttcctta tctaaacgac aagcgtgttt atttagttgt tttgaacgtc
    25441 tttttgaaca catttattct tagtcctccc tactcttgtc taaacatgaa gtagtaattt
    25501 tcataagatg atttcattat ataaataaaa tcaaaagaag atggactatt aggagagtat
    25561 tttttttgat tttttattgt ttcaagaaaa tcggaataat aacttatgta ctttttaatt
    25621 ttgttaagta atatatctag ttatatctag ttatatctag ttaccttttc tttgaaaaaa
    25681 acataaatca gctaataaat atgtgagaca aagctgccat ccataaatac tagctgattt
    25741 tttcagttaa atgtctattt ttttctctga tgatggtatt tccaaaatat tcccagtcat
    25801 ctggagtcgg tggatttttc caaattatct gttctttatt aaatttttca agtaaacaat
    25861 cagataaata aatattcgta cgagaagtga ttcgactctc aatcacaata ttgtaatttt
    25921 taaatccttt cacttgagaa ataatgtaat cggtataagc agatccttgc gaaaaatcaa
    25981 tacagacatg aatcggtgct tcaaaatatg ataccggaca aataccgacc aataaaaaga
    26041 gataatcata aaataagcga atcatgaaac gttcatcttt tcccaagaaa tagcgtttat
    26101 tctcttgtat gaccttttgg attgctgtac tgaatattgg atacgtctcg aagaaaaact
    26161 gtagctgctt tttagacgta aagctagtca tctcaaagtc gaatatccaa ttttttcgat
    26221 tgacatgcat catacccata cgaagttctt ttcgtatata tagtctttct tcttcagaga
    26281 tttcaatcga aaatggtaat tgatcaatca attccactga cattttttga ctaatcatgt
    26341 ggatatcatg aaaatgagct tccgcaagtc caaatgcgcc atctaattca aattcttctt
    26401 ccgtgatcaa aaacaacatg atataagaaa tctcatcaat gatctgctct ttagggatat
    26461 gaagaaaaga aatatgtgat aaatccttga tgatcttcat tccttctgag ctcttaaagt
    26521 attcatctga aaagaaacgt tttccgattg gttgattccc ataggccctc aacaaactaa
    26581 tagtggttag caaattgaat ttgattcgtt ttgttgcaga cagttttaaa ttgaacagat
    26641 attcaaaata ttgcacgata ctctttgctt cattcatgac gctttctcta aatggcatag
    26701 aaaaaccatt aaagaccccg aaatataccc caaataatac gttccgtatg tttatttctt
    26761 ccccaactaa tatgtttttc tttaacttta tttgatgctg ttcaagaaaa gagactaatt
    26821 ctcttctttt tacataggct cttgatatgc ttaaaaaatg attctctgca aatttttcga
    26881 tcgttacttt tgaatccacg atctccgtta acagtcgagc aatttttgat cgttgaaagt
    26941 agattcttct taaatttttg atatccgtca aattcagacg ttcgacatgg atctctgctt
    27001 cttctgaaat ttggatctct ggctttgttt tgaattcagt aaattcttta tttaattcta
    27061 tgatataatt tcttgtttta aatttagaca aacctaatgt ttcatataac ttaggcagca
    27121 ctacataatt ctttttctca aattctaaat atctagctag cagcagtttt tctctatctt
    27181 cctcttctat aaggtaatcc aacttcatat cctacacctc aaaaaatgcc tcataccaat
    27241 tacttgatat gcagatgaaa gttcatcttt tcacctatac tgattttatg atggattatg
    27301 cttgtttttt catcagttat tctcattttt tatctttttt ttgagaatat tgcaaaaaat
    27361 ggaaaaattt atgaggaaat attctatatt ttttgtttta ttgtgttaaa atgtacaaga
    27421 tttgcgccat ttgcgtaaac aaccacaaaa aagagcagga cggccaccgt cctgctcttt
    27481 tacttatttt aagttccatt acttattaat tggctaaact tctgcttgtt tctgatattg
    27541 cttgtttttc tccaatgatc cgcacttctg tttctaaaga cacatcaaat ttttctttga
    27601 ttacttcttg gatgtgcgca atcaattcaa tataatctgt cgctgtcgca tgatcgatat
    27661 tgacgatgaa tccagcatgt ttttcagaga cttgtgcacc gccccatttc aggccttgca
    27721 atcctgcttg ttggatcagc tgacctgtat agtgtcctac tgggcgctta aagacacttc
    27781 cgcatgaagg gtattctaat ggctgttttg attgacgcaa ttcggtcaac tcatccattc
    27841 ttgctttgat tgcttcataa tcccctgttt gcaaactgaa tcgagcttcc aatacgatag
    27901 cacgtaattc ttggacttta ctgtgacgat aagaaaatac catttcgtct tttgtcaaag
    27961 ttttcaatgt tccatcttca agcaaaagat ccacttcagc aaaaacatct ttgatctctc
    28021 cgccatacgc acctgcattc atataaaccg ctccaccgac acttcccggg atgccgcaag
    28081 caaattcaaa tccagtcaat gattctgcca aagctgcata agtcgtatca atcagtgagg
    28141 cacctgcttc cgcaatgacc atcgttcctt tgacatgaat ctgtttcatt tcagtcagca
    28201 tgatgactac accgcgaatc ccgccatctt gaacgatcag attgcttgca tttcctaata
    28261 ccatccaagg tatatcatgg attcggcaat aatcgatgat ttgctttact tcttcttgtt
    28321 ttttcgggaa tgcaaggaca tcagctggtc cacctgtttt cgtaaacgta tagttcatca
    28381 atggttcatc aaacaatata gtaatcgtgg ctaagctttc aactatttct tctttattca
    28441 ctgaggattt tcctttcttt tctcaaacgt cctcattatt ctatcacgct taatacaatc
    28501 ttgccagtct tgttcaaagt tgatgacggt agtgatcttt aagcacttcc tcacataatt
    28561 catgacttct tacaacttct ttttgtttaa gcaattctgt ttccgattta cctaaacgga
    28621 tctgagaaaa gaaggcctct accattggct caaacccgcg tttgactagc gtgtttgtcc
    28681 agtcgccaaa ttctttcact ttttttccat cagcatcttg aatgacaagc tgggtcagat
    28741 cgtttacttc ataagtacca tttttacttg ttacttgata tttttctata ttagcgccac
    28801 ttgctaaatc catcgttaaa atagccgttt gattttgtgt ttctaattgt aaaatggcat
    28861 attccaaaaa ttcctttgtt tctcttatct ggtattttgt tctcaaaatg ggttcatcta
    28921 ataaatacac agctgtatca ataagatgta aaaacaaatc ataaaggacg aactctgtcg
    28981 tttcttttgc cgctattcga tttttttgca ggtggatcaa ccgcttatct gggatacgtt
    29041 tcaattcttc taccatagga gcaaagcgcc ggttgaaacc gatcatcaaa attatttggt
    29101 tcttatcagc taattcttgc aattcacgaa cttcatttag atggacactc agtggtttgt
    29161 caatataaac atggatacca ttttctagac attttttggc taattcataa tgtacttttg
    29221 ttgctgcgtg gatcatacat gcttcgattt tttcttctaa aagctcatcg atcgtttcat
    29281 atagatgttg gaacccgtac tctttttgaa ttctttcttt tgtttcttta tttcttgttg
    29341 caaaataaaa atcaagtgtt ccttgttttt tcgcataagt tggtaaatat gctttttctg
    29401 cgatattccc tacaccgatt acaccaatct tcatctactt tcctcctgga tcatttagtt
    29461 actttcatct tacaccattt tttactaaaa tgaggtacaa tagtatcgca aaggtaagga
    29521 aattaattcg aaggagtgtg cttttattga aatttatctc ttggaacgta aacgggcttc
    29581 gtgccatcgt aaataaaaat tttttagaag tttttcatga gttagacgcc gattttttct
    29641 gtctgcagga aacgaaactc caagcaggac aaattgattt agatcttcca ggttattatc
    29701 aatattggaa ttacgcggaa cgaaaaggct attccggcac agcgattttt gctaaaaaac
    29761 cagcattgaa tgccacttac ggaatgggta tcgatatcca tgatacagaa ggccgtctga
    29821 ttactttgga atattccgat ttctttcttg taacctgtta cacgccaaat tctcaaagcg
    29881 aattaaaacg tttagattac cgattagaat gggaagaagc cttttataat tatttggaaa
    29941 atctaaaaaa acaaaaacca gtcatcgtgt gtggggatct aaatgtcgct catcaaaaga
    30001 ttgatttgaa aaactggaaa acgaatcaaa aaaatgctgg attcactcca gaagaaagag
    30061 cggctctttc tcgactgttg gataacgggt ttatcgatac attccgttat ttttatccaa
    30121 cccaggaagg tgtctactct tggtggaact accgattcaa ttcaaggaaa aacaatgctg
    30181 gttggcggat cgattacttt ttgacgagca aagatttaga gccaggacta gctgatgcaa
    30241 agatccatac ggacattatg ggcagtgatc attgtccagt agaattagat ttgaaataaa
    30301 gaggttgtga aaaagtcgtt tagtttcgag tattaagaaa aattttgtga aaatggcttt
    30361 ccacattttg cataaatttg gcataatacc gagaaactgg cttttgaaca ctgtttatcg
    30421 agagattgtg aaaaagctgt cctgcatcaa gtaataagaa cagccaaaca aaaatagttc
    30481 ctcatatttt tcgtttggtt gggcttatta ccgcagatac aagcttttga acaccgttta
    30541 ttaagaggtt gtgaaaaagc tgcactgcat caagtaataa gaacagccaa acaaaaatag
    30601 ttcctcatat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt tgaacaccgt
    30661 ttattaagag gttgtgaaaa agctgcactg catcaagtaa taagaacagc caaacaaaaa
    30721 tagttcctca tatttttcgt ttggttggac ttattaccgc agatgcaagc ttttgaacac
    30781 cgtttattga gaagttgtga aatcagcgtc ctgacctgag tattagagaa acaaatggca
    30841 aaatagttcc tcatattttg ctattttttg agctaatacc gagggtcagc tgattgaaca
    30901 ccgtttagtg gagaagttgt gaaaaagtcg cctactttcg agtcgtaaga aatttttttg
    30961 aaaatggttc ctcacaactt tgcataaatt tgacttaata ccgagaagtc atgatcccca
    31021 tctaactcca aatcacaagg aatgagttca aaaactagct tttctcaaca aatattacat
    31081 aaaaaattct atgttttttg ttaaatttat ttgctttttt caaaagtatg ttacagtaat
    31141 ttcccaagga ggttttacag aaatgaattt tgttgccatg gattttgaaa ctgccaatca
    31201 tcagccttat agtgcttgtt ctcttgcgct agtcatggta aaaaatagcc agatcgttga
    31261 tgaattctat acattgatac agcctgagac tccttttttc tggcgaaatg tccaaattca
    31321 cggaatccat caagaagacg tacgcaatgc gccgaaattc ccagaagtct ggcaaactat
    31381 ccaaccatat tttcaaaaaa atcgtttagt cgttgcacat aatgctgctt ttgatacaaa
    31441 ggtcttagcg ggatgcttag attattatca tcttgaacag cctaattatc tttctttatg
    31501 tacagtgaaa agtagccgtc gcctgtttcc tgaatttcca aatcatcgat tgaacactgt
    31561 gtgcgaaaat ttgaacatcc aattagatca tcaccatgat gcattggaag atagtcgtgc
    31621 atgtgcggaa atcctgcttt atcaagaaaa aaaattcggg acagatccat tgaaaaaact
    31681 tgtgactata aagtaaaaga atacttatga aacacacaaa gaggtcgtga gcctgccgtt
    31741 tcactccgag tcacaaggag caatttcaaa aaatagcttc tcatgtttat taaatattgt
    31801 gactggtgac cgaggagctg gcaggagaac accgtttatt ggagaggttg tgaaaaagct
    31861 gttctgcatc aagtaataag aacagccaaa caaaaatagc ttctcatatt tttcatttgg
    31921 ttggacttat taccgcagat gcaagctttt ggacaccgtt taccaagagg ttgtgaaatc
    31981 agcgttttga cctgagtatt agagaaacaa acggcaaaat agttcctcat attttgccgt
    32041 tttttgagct aataccgaag gtcagctgat tgaacaccgt ttattcaaaa aaaatggact
    32101 gcgacacgac ttttgtcaca gtcccttcgt gtgtttttct gccttctcaa aaggatgaca
    32161 gtttctcact cttttcctat ttcttctatt caatcaaata actcatttta tatacatcta
    32221 aaaattcacc tagatctgtt cttgcccctc taggcatgac cgcttcgatt tggaagccca
    32281 tttttcggta aaggtgtacg gctctttcat tacgaacttg aacgtcaagc tccaatcgaa
    32341 aaagtacacc catttccttc gcccaactga tgatttcttc tagcataaga gtgcctagtc
    32401 ccattcccca atattcctgc agaatactga taccgacttc tcccacgtga gacaaacgaa
    32461 attgactgtc tgccttgaca gatgctgttc caataatcgt cccttcatag attgcaagca
    32521 gcaataaatt attattgctt tcgtatatat aatccaactc ttcttctaag gtttctggtg
    32581 gtaacaggag ttctgcttca tccaaaacta aaaattctgt ctccttatta acttgtccca
    32641 tcatcaaaag aatgtctttt gcatctcctg gcactgcttc ccgcaagatg atcccaactt
    32701 cttcactcat gattttcagc ccatttttct agaattcgct gtttgaaggt ttcactttgc
    32761 tccccgtatg agattagttt cacataccgc ttttctaaat ctgtatcact tttttctaaa
    32821 atcagttcca aataatcctc cggcagtgct tcttctaata gatttcccca ttcaacaacg
    32881 gaaagcccat caccttcaaa atattcatct aaccctaaat ctgctccgct agctgctacc
    32941 cgataaatat ccatatgata caacggaatc cgaccttgac tatattctct aataatcgtg
    33001 tatgtcggac ttttgatcat ttgcgttatc cctaatcctt gggcaattcc tttcgtcaac
    33061 gttgttttac ccgcacctag atcaccagtc aatatcagat tgtcacctgg cattgcggaa
    33121 tgaccaattg cctctgcgaa ttgttctgtc attgttaatc ctgatagttc gatcattttt
    33181 catcttctcc cgctcttctt tctttttgcc agtatatcgc gtaatgaagt ttttttaaag
    33241 aaaaaatgaa ctagtcaaga acagcagctg ctgtttttgg ctagttcgcg tgtatttgtt
    33301 aatcaatcaa tgtttgtgct gctgtgataa tcgataattt atatacatct tcttcatttg
    33361 ctccacgaga caaatcagaa accggtttgt tcaagccttg tagaattggt ccgattgctt
    33421 caaagttacc gaaacgctga gcaattttat agccgatatt tcctgactgc aattctggaa
    33481 atacaaagac tgttgcttga ccagctactt ctgaatctgg cgctttcagt tgtgcaactg
    33541 aaggaacata agaagcatca aattgcaatt cgccgtcgat catgtattgt ggcgctagtt
    33601 ttttagcgat tttagttgct tcaactactt tgtctacttc tggcgatttc gctgagcctt
    33661 ttgtcgagaa gctcatcatt gctacttttg gttcgatatc gaacaattct gctgtttttg
    33721 cagaatctac ggcgatttca gccaattctt gcgcagttgg attcacgttg atcgcacaat
    33781 ccgaaaagac atatttttct tgatctcttc cacgtaccat gatcatcgct ccgcttgtcc
    33841 gactgatgcc aggctttgtt ttgatgatct gaagtgctgg gcgaacagtg tcgccagtcg
    33901 aatggatcgc tccagagacc attccgtctg caatccccat atacgtaagc atcgtaccaa
    33961 agtaattcac atcttttaaa atcttttctg cttgttcttt ggatgccttt ccatttctac
    34021 gttcaacaaa agtatccacc atttcatccc acttatcgta attatcaggg ctgatgatcg
    34081 taaagctaga tgttttgatt cctctggcat gcgctgcatt tcttatttct tcttcgttcc
    34141 ctactaaaat gggttccaca agttcttctg ctttcaaccg ggcagctgcg cctaaaatac
    34201 gagcatcagt agcttccggg aaaacgattt tgatcccacg gcgaacaatt ttaaatctta
    34261 aactatcaaa caattccaca agatgacctc cagacgtttt tatatgtatt atcatacact
    34321 attccagaaa aaaagaacag tttattttat ctgtatcagt caaaaatgct ggaaaaatta
    34381 agtttttcac atacaaagcg aactgcacta taacaggaaa gcgctgtttt attacactgt
    34441 ttcaggcagt tgccaatcaa tcggttcttc tcctaacgca aggagcgcat cattcgtttt
    34501 cgagaagggt ttggaaccaa aaaagccacg acttgcagat aacggactgg gatgtggaga
    34561 tgttatgatg atatggcgac tcttatcgat cattttgatt ttttcttgtg ccggttttcc
    34621 ccacaagata aacacgattg gtttttcccg ttcatttaat ttttcaatga tcgtgtctgt
    34681 taatctttcc caacctttcc cgcgatgaga atacgcttgc ccttcccgaa cggtaagaac
    34741 ggtgttgagt aaaaggactc cctgtttagc ccatgacact agatttccat gttgaacagg
    34801 tgcgattcca agatcatcat aaagctcttt atagatattt cttaacgatg gcgggatctt
    34861 tacgccaggt tgcacagaaa aagataagcc atgagcttga ttttctccat gataaggatc
    34921 ttgtcctaaa atcaccactt taacttcttc ataaggagtc aattccaatg cttcatagat
    34981 atgatacata tctggatgga tcttttggga cgcatattct ttttttaaaa attctcttag
    35041 atgcagataa taatcttttg aaaattctga ggacaaaact tcttgccaac tgttatgaat
    35101 gatttctttc aaaaactcca cctcctaata aaaagaataa ctcacatttt cttcaatcac
    35161 aagggacaat cttcaccctc agcacttgat taatatggta aactaggaac aagaagcaga
    35221 aaggaacgat aatcattatg atcaaattaa ttgcatcaga tatggacggc acattattag
    35281 atgcccatat gagtgtttct cctgaaaatg ccgaggcgat acgttttgca aatgatgccg
    35341 gtgttgagtt catggtcgct actggtcgaa actatcaaga agctcgcgca gctttagatg
    35401 aggtaggaat cgattgtgcg atgatcactt tgaacggggc acaggtattt gataaagaag
    35461 gaaattcatt gtttaccgtg tcgattccaa ataatcaagc aatctctgtt ttagatattc
    35521 tagatgctaa cggtatttac tatgaagtag caaccaacga tggtctttat tctgaaaatc
    35581 aagcgaaacg aattgaaagt tttgcttcca tggtggctac ccatttacct caccttacgt
    35641 ataaaatggc gattgccatg gcctcagcta agctggagtt attgcacatc acatacgtgg
    35701 acagtattcg tgctattttg gaagaaaaga atctggaagt tttaaaaatt atttgttttc
    35761 atacagaagg gccagctgta ttaggtccag ttggaaagca gatttctctt ttaggcgatc
    35821 tagccgttac ttcctctggt caaaacaata tcgaagtgaa ccataaaaac gctcaaaaag
    35881 gaattgctgt tgcccatgtc gctcacgagc gtgggatttc tttagaagaa gtcatgacga
    35941 ttggcgataa cttcaatgat gtcagcatgc tgcaagtagc aggagtcagt ttcgcaatgg
    36001 gaaatgcaga aatcgaagta aaagattatg ccaaatatac aacggacaca aaccttgaat
    36061 ctggcgtagg aaaagccata ttgcgcgcga ttgcagaaga cttgtagttt tatctagaaa
    36121 agagggatat agatgtcaga atttttcatt caggaaaagc agcttggacg tgcaactcgg
    36181 acaattgtca aaaacgaaaa aggacattcc ctgtttttga tggttggtcg ctggggaaca
    36241 aagggcgatg cattgtctct ttatgccatg aatggcgatc tcgttgctca catcaagcag
    36301 ataagcctga cattcggtac gcgttttgag ctgtataaag agttcgaaaa ggtgggaacc
    36361 atgcagaaaa tattcaattg gcccggtgac ttttattata ttcgtagact tcactggaca
    36421 gtccaaggtg atatctataa tcatcaatat caaatccatc atttcaatca gcaaatcatg
    36481 aaaatggata aagcaacact tttttcagga gattactatg tattggatgt ctcaaatgat
    36541 gaagatgctc cagtttgtat ttgtattgct gcggttttag attactggct ctaccgtaaa
    36601 gacaaaagtc gcgataagcc tgtttcttac cgacttaact taagttaaaa agatgtacct
    36661 gaaatgcgga aatacgcatt tcaggtacat ctttttagat attcttttgc atatgatcat
    36721 aaagatgacc actgatcatc cgctgaccga caactttgaa gtcatggcgt tcgtataatt
    36781 ttttagcctt tggatttttt tcatccacac ttagaccgat gacggagcga ttagctttct
    36841 tcgccaattt aggtaatgct tctaataatc gcgaaccgat gccttgtcct ctaaaatctt
    36901 ctgatacact gatagagtcc aaataccatt cgttgggaaa cgtttcttta tcaatgaaca
    36961 aacgtgtaga cgcatctagc tgatatttct ctaagatagg taccagtggc tgatcgatga
    37021 ttgattcttc ttcatctgta taaccgtaag caactcctgc aactttaccg tctatttctt
    37081 ctacgatacc tcgtgaataa ctgtaacgat aatttggatc agtgattgct tcttctaaaa
    37141 tctctaaagt cttttgttcc cctgtctgct tcaaaaatgg cagttccata tcttttagaa
    37201 tcactaagat caatggggcg atttctggag catcttcttt tctcgcaaaa cgaatcatag
    37261 tttcctctcc ttttctccat tctaacatgc agaaaaagaa atcgcaaaat cgttatttta
    37321 aaaaatcttc aatcttttca gtaatgaaat aaccatgagt aacgattctt gccgcttcag
    37381 ttcggcaata agggcagacg actggcattt ctttatcatt atgttcgact acattattga
    37441 cttcttcgta tgcaaatttt tttccgcaat tagggcattt cattttttcc atgttatctc
    37501 aacttccttt catctttact ctcttagctt actcttatat tgtaaaaaag agaagcaata
    37561 tccttcttct atgcagatat ccatacctga cggtcctgtt ctccatctat taatcggact
    37621 ttataataag gacgttcatc tttgactaga agtgtccact ctttcacttt tgcttttttc
    37681 ccgtagtagc tgactgcttc cttcatcgct gcttgcggtt gtttgaactc ttccgttttt
    37741 tctatatcaa aaagatgttc tgcggccttt tccgtgtcat ttcgtacggt tgttttccca
    37801 gtggatggat tgactgctat gacttgtcct tcacaaaaaa actggtattc atatgttgca
    37861 ttcgtaggat tctccaaatc tttttcaact gcaaaatgaa tagcagatat gttatgttct
    37921 tttgtttcgt tttttacgat tgctgctgct tttttcaatg agatccgata ttcctggtca
    37981 ctaatatcat ccatgtgaaa agcggcattg agcagtcccg tcataccggt aatccctatt
    38041 acgatgaggg cagcaacacc aaacatcatt tttttcattc ttcattctcc tgtttctttt
    38101 ttttaaagaa tatcaagaaa tgaacgaatg aaaaatcgaa tgaaacgaaa aaaaagtgac
    38161 aattttgtta tctttattcg tgcagttcta atggcaatcc gtctggatca aagaaaaacg
    38221 tcattttttt tcctgtaaag gtatcttctc taatcggttc tgattcgatc cctaaggact
    38281 gcaattctgc aattgtttct tcaatatcgt ctactttgaa agcaagatga cgcaagccac
    38341 aagcttctgg atagtttggt cgttgtggcg cattagcaat tccaaaaatc tccaattcag
    38401 cacttcctag tttcagatct aatttatagt catctcgttc tttgcggtaa ttttctctga
    38461 ttacttcaaa tcctaattta ttaacataaa aatcacgtga tttctgataa tctgaaacaa
    38521 tgatggctat aggatggatc gttgtaaggt tcatatgagc actcctattc ttcgtttaag
    38581 ctcggatcta tattaatctc cagttccatt gtaaatgtgt cagattgaaa aaaatagctg
    38641 tttttccttt ttataagaaa aaaggcaaaa aaaacagaaa gtaggtcctc caagacactc
    38701 ttcctgttcc caatataata aatgaaagta agaaattata ttttcaagaa aacaaacaga
    38761 aaattatcat aacacaaatt atttataatt gaaagactag ttttttttca agaaaagcat
    38821 acaatagatt gtgttagtaa atacagaaca cactacattt agtgtcttaa ggagtcctca
    38881 tacatgaagt catattttca gtttttagct catcagctaa aaggctggcc gcaacaaaat
    38941 tattatcttt tctttttcag tcttggctgc caggtcatga ctcttgtcaa tagtcccatc
    39001 acttggctgt ccgttattac atttatcggt accacgcttg gtgtattgtg tattttatcc
    39061 atcaatgcgg caaaatcagt caacggtatt ttaggtattt tgtctgcgat ttgttttatt
    39121 atcgttgggt tttcagcaaa gaactattta agtatcggtg aacagattgc ttatatgatc
    39181 acattggata tccccgtatt gttaagtaaa gaatggaatc ataatatggc ttcaaaaatc
    39241 cgaaaattaa ctggaaaaag ctggtttatc gcaatcatca gtactttcct tgtctatctt
    39301 gtttcaggat tcctgattgg tcgttataca gatgatcctc ggccgtgggt agatgccatt
    39361 gctttttcta ttagcttgac tgctggtatc atcagtttct tgcgttacaa caaccaatat
    39421 tactggtggt tagcttcagg gcttgctcaa atggtccttt ggtatatttc atttacgcat
    39481 ggatctgcaa gtttggcgat gttcgtgaac agctctgttt acttgctgaa tgatgtcctt
    39541 gcatttaccg tttcaccttg gtataaccaa aaagaacgtg aacgtatgca aaaaatggaa
    39601 gaagaatact acaacgcaca acaacacgca taaaaaaact gagcgtggga caaaagtaaa
    39661 gaacactttt gtctcacgct ctaaacacgt ataaacggcg gaatcagaag caactccttc
    39721 ggaaataagc tgaaattcac aaaaatttga aaagcaattt tcgtgaattt cttcttattt
    39781 cttggagtta aacgcttctg tcccagcctc tattttttat agtaattcct tcagatactt
    39841 tcttgcctca tcattgaaac gcagtgattc ttctaacttc tgataatatt ccaacgcttg
    39901 tttctgagct tcagtaaaac gataatgttt tcctttccat ttgtcgattg tctcttgcac
    39961 atttccagat tggatatctt tcactactag ttgccatttt tcttttgaga ctgtacggtc
    40021 tttcttatca gcagattgta tagcttctcg ttctttacgc aatactttta aaaaaccatt
    40081 tctgactatc cgaggaatgc tgtcgaagaa cccttctgta aaaccatagc gacaatattg
    40141 cttccaaata aatagataga tttttggttg gatgaatcgt tggtttttcg caaaatattc
    40201 catctgagca gtgacttctg gtgttcgttg acgttttgtc tttctcaaca cggaaataaa
    40261 tgtttcaaaa taagcattag gatgtactgg cacttcttca tatacgatgg attgccaatc
    40321 tttacgtaaa aatgcgcgat agttgatcaa gaattcttct acatccttta ctaattcttc
    40381 tgcaaagtcg tcaaatagtt ctttttttat ctgtcgcttt tttgactgcc cattgatgtg
    40441 ttcacttatt ttcttgattt cattttccaa tgcttgataa tccgctatgt aaatcggcat
    40501 ttctacttgg cgaaattctg cgagccgctg agctaatttt atatccggta aatatggctg
    40561 tttcatccga cgattttggt acaagacaaa acagtatttt tgccatagtc cttcaggaaa
    40621 atcgatattc ttctgcttaa gccataataa ttcgtctaag gccagatcaa cttttgtcat
    40681 tccctgatgg atcgaagctg ccactgtcgg agagacatgc aggtgatcgg caaagtggtt
    40741 gatgcctagt tttaggatct ttccggtttt tggcgattta acgatgtatt gcacttttaa
    40801 ttctctacca cactcacaat acaatttttg ctggcttcgt tttgttcgaa aaaacggatt
    40861 gatcttgaag tcagaaaaca cccaatctgt tgcagctaaa taatgttctt ccataaaacg
    40921 agagctgatt agatatcggc ggtgcttatc gactagttcc cgctgttttt tcgttaattt
    40981 tgcatagatc tcccaacgtt gactgcttgt gtattgttta gaaattttga tgggatagct
    41041 tttgctgatt tcttttggaa accattcttc aaagacggat tgccattctt ccacggctgt
    41101 ttctttcctt tctaattaca aaaagctggc tactaacata acgttagcaa ccagccagtg
    41161 tttcttgcta aattagtgag ttgttccggc atttccggaa atatcttctt tattttctac
    41221 tgctgcttca actgcataag tcaaagaaga agcaatgtct tctaaagaca tagaaggcgt
    41281 acccactgga cgatcgatca cttgatcggg tgagaatggc acgtggatga acccacctcg
    41341 aattgccggg aattgtgttt cgatcaaatg aagcaaacga tacatgatat cattgcagac
    41401 aaatgttcct gctgtataag agatgtacgc tggtagacca tgatcttgta cattttttgt
    41461 cattgctttg attggcaatg aggtaaagta agcggctgga ccgttttctt ctaaagccgt
    41521 atcgaatggc tgatttcctt cattatcagg gattcttgct tctgctagat tgattgcgac
    41581 acgttcgaac gagactgctg accgcccacc tgcttgtccg acacagatca cgacatctgg
    41641 ttggtgctgt tggatggctt ctttgactac ttgactgctt ttttcgaata cggtcggtac
    41701 ttccactttg atgatttcag caccgctgat ttcatctggc atttttttta ctgcttcata
    41761 ggctggattc actttgtccc caccaaatgg atcaaaacct gttactagta ctttcatctg
    41821 ttgttcctcc gtccgattga tttaacatat ggttatcttt tatcatacca ttttccttga
    41881 acagcgtaaa taaaggaaac aatagtttaa ataacataac agatcaaact taatatattc
    41941 ttataaaaaa atagtgttcc actacaatgt tagaagaggt tgcgacaatt attctgtcac
    42001 aacccctctc ttctattatt taaatagaat catataagca atttggaaaa ctagcataaa
    42061 taacgcaata aacaactggt ttttgatcac tccgtatttg tctttcatct ccagcatcgc
    42121 tacaggcacg atattgaagt tagcagccat cggtgtcagc agggtcccac aaaaaccgca
    42181 agtcaatgca accattccta ttaacgctgg attcgctcca tgactaaata cgaatggtgc
    42241 accgatccca accgtcatca cggtgatggc cgcaaatgca ttccccatga ttaccgtaaa
    42301 tatcaccatg ccaagagcgt aaatgatgat gccgatgttc acatttcctt ctggaacgat
    42361 cgtacctact gcattggaaa tcactgtccc aactccagcg cttgtaaata ccgcacctag
    42421 agaagctaaa agcattggca acatgcttaa cggccctact gtgcccagca tatctgctgc
    42481 atcatctaaa aatgtacttg gtcgattatc tcgagaaaag aacatcaaga ttagcatggc
    42541 tgcaaaaaca ccgacgccca cgccgactaa agcacctaaa ttggtaaata gagcaaacaa
    42601 gatcgcaaag acaccgatac tcaaagctgg aataaaaatt ttcattccta gtttgtctga
    42661 cattttttcc atatattctt ttgatggaag ccggctttct cctttgctga ctttcttagc
    42721 aattgctggt atggtcatcg caaagatcaa gccaccgttc acgattgccg gaagccatct
    42781 tcctcctgca ataactaccc ctaagaccgt ccagaaaaag gctgacccat aacgatgagg
    42841 attggtttta tctgttaaat ttcttactcc agtgtaaatc aatacgagtc ccatcacgat
    42901 ataaaggatc tccagtaatt tatcgcctaa taaaatatca ggatttgtaa aaaagtccat
    42961 cttattgccc ctttcctgga taatatttct tcgctaattt cttttcttta agatagaagt
    43021 agacacttgc cacaactaaa gccgtgatag ccactggaac ttccactaaa gcaagctgtc
    43081 ccaatgttac gtcatatcct agatctttca gtgttgattg gactagcaac gcccctgctc
    43141 ctccgatgaa tagtacttgg ccaaagaacc agcagacatt ttccatagct gaagccatac
    43201 cttttagttc ttcttcatgc ttaggatgga cttctaaccc ttttgattcg atggtcccca
    43261 atgccatcgg taaaatgatt ggacgaacaa atccagcaac tccaccaaaa ctcacgttaa
    43321 aagccgcaaa gatcattcga aagatcccat aaatatctac aatcatacca gcagatactt
    43381 tcttgaatcg cttgatcaag gaagccgctg attctttcag accatttctt tcaagcgttc
    43441 ctgttgccaa cataatgatg ataaaaatcg ccatcccgcg attgtttaca aaacttgtac
    43501 ctaaaagttc taacattcct tgaatgccaa gaccgccagt caaagctgta acaactaaag
    43561 caaccattac gatcaatatc gagtctaatt taaatgcaaa cccgagaata acaatcaaga
    43621 cgcctaaaag gctaagataa ttttccatat attttcctcc ataaaatgac aatatttttt
    43681 taattataaa gcaaaacaca taaaaaatat agttgttttc tcacgaaata gacactattt
    43741 ttaaatattt ttcgttattt ttttattata taattcacct tacttattgt aagataaagc
    43801 tttttttaat ttattgcctg ctaatatata aaaataaggt ctagttactg tttttttaaa
    43861 tgattaataa ataacaactc ctttctatga aattgcaaag cattcatctt cttttctgct
    43921 aacgatatat ccgtcaatgc ttgttacact ttactaaaaa gtatgagatt gccgatatct
    43981 ggataggtgt gctatactac agaaaaagat atacgatctg ccaccgggta gtaaaaaaga
    44041 ggatgatcat tccattaggt ctttgaaggg atgattctcc tctttttgtg tattttttat
    44101 attgaaggag gaacgtatgt atggcatgga tggaattaat catagcagga attttggaag
    44161 tattctggtc aacgatgatg aaatggagtg atggtttttc taaaatcaat tattcttttt
    44221 acacagtgat tggaatgatt gctagttttt actttttgtc aaaggcaatc aaaagtttgc
    44281 ctatgagtct ctcttatcct atttggacag ggattggcgc agttggttcg gtcattattg
    44341 gtgtggtctt gtttcatgat aagctgaatc tttccacttg gttctttgtc gggttgctgc
    44401 tcatcagcat cattggcatc aaaatcacta gcggtcacta gatacttaga caagcagaca
    44461 aggactgatc agaaaaagcg gggcttttta tttgatattc ctctttctat gaaaaaacaa
    44521 gaaaataaga ctaatgacct agcgacttct ctactcatca ggtgtatgct tgtactatct
    44581 atagaaaagg agtgaatatt tttgaaaagt ctttcggtcc aagaattatc caagaacttt
    44641 ggtcacaaac aagccctcag cgatgtcagt tttagcttat ctcctggcaa aatcgttgga
    44701 ttagtaggtc ctaatggcgc tggaaaaaca acgatcatga aagctatttt aggactgatc
    44761 cattactcag aaggaacgat ccgtattggt gaaaatgaga tttctccctc tagtcataaa
    44821 ggattagaac aagtaggagc attgatcgaa tatccgggta tctatccatt cttaacaggt
    44881 tatgatcatc tgaagttatt ctctgaaaca aacgatgtat ctgctatcga cactatcgtg
    44941 aaacagctca agatggaaaa atacattcac aaaaaagcga aatcctactc gctgggaatg
    45001 aaacaaaaat tgggaattgc tcttgcctta ctgaaccatc cgtctatcgt tattttagat
    45061 gagccgatga acggtttgga tccacaagca acaagagatg tgcgaaaaat cattaccgac
    45121 ttggctactc agggcacctc tttcttgatc tccagtcact tactcagcga gcttgaaaaa
    45181 atggtcgatg agctgatcct gatcaatcaa ggaaaaatca tcaaacaatg tacaatggct
    45241 gaattgaacc aaacagcgca agatttcatc gttatctcta cgacaaatga tcaagctgct
    45301 cgaacgatct tgacagacgc tggatatccc ttggaagatc ctgataaaat caagcttcta
    45361 aaaaaaaacg aagagttatt aggaactgtt atccagttat tgtctgcaga aaatgtccat
    45421 gtgacagatg tccagcatct gacgaatgat ttggaatctt ccctattgga aattctggat
    45481 tcagtaaagg gggaagaaga aaaatgacgt tgcttataaa acaagaatta tttaaattga
    45541 tcaagaaaaa gtcaactgct gttttatctg ttctattagt tgctttgctc ataggaacag
    45601 cacttctagc caaaaaatac acgacgatca ttgatccagt tgaaatgact gctcagcttt
    45661 tcagtgccac atcttggatt gtctttatca tgattgctgc tgcaagtacg atcatttcaa
    45721 tggaatcaca atatggtaca ttgaaaaatc tcctttatcg aaagtattct cgaggagaaa
    45781 tattagtaag taaatggatc acattagtta tttattctat ttatttatac cttttagcta
    45841 ttattgtcac cgtgctgatg aaactgatcc ttttcccttc gatttccttt acggagaaga
    45901 tttctactgg tcagacactg atccaaagct tattcactta tactttgggt agttatatcg
    45961 gtttatggct aattttaagt ttagtgttga tgattgcttg ttttatcaat agttccggtg
    46021 cctccatctc agcagggatc gtcttttatt ttgcttcatc aatcatatct ggtatcctca
    46081 tcgcactcat tcaaaaatgg gagtggatca aatggaatcc aatcagtatg ctgaatctgc
    46141 aaaaccaaat tggcaacgaa gagattatga agcaattgac tcatctttct actaatcaaa
    46201 tgctgtttgg caatttagct tacattgctt tgttcttagc attgggatac ctcgtattca
    46261 agcgaaaaaa tgtatgatgg ttcattaaca aagaagttgt gacagaagtg gccagtttca
    46321 agaaatttcg gcttattttt agaagaagct acttcttgaa caccatttat tcaaaaaaag
    46381 aagcgatgac acgaatgttg tcaccgcttc ttttttgaat aaaccacagg cttcacagcc
    46441 tctctttata cttctatacg tgaagcatcc cagtggcaaa taaaaccatt gcgattactc
    46501 cgaccatcgt cacaccgata agtaaaatct tatctaagtg gatatgttgt acaggttcgt
    46561 tttgttcttt acgtgctttg aggtaaaaat aaatacctgg taagaaaaga acaagaacaa
    46621 gcatcacttc attaaaggct acaactagca tggcccatac ttgaaaagca cttgctaaaa
    46681 accctactaa aaattggacc cactctttcc gctgataaga aagcttcatt tggtacagcc
    46741 ctaagaaaag ccacgtgaag aaaatcgctg ctgtaccaag tgtataagca aagttatatg
    46801 cactgtcagt gaataataat gaaagtaaaa agacattcgt acataacgtc gtcaatacga
    46861 tagcataagt tggtgcccca tttttgttga gttttcccca tgctttaggc aaaagtccgt
    46921 cctcagccat attccccatt gtttcaatcg gcaagattgt ccatgagagc caaaccccaa
    46981 ctaaagaaat gatcaaaccg ccgttgatca cgaccgcccc ccatttacca accatcattt
    47041 caaatacata tcccatagca ggttgcgctt tgatcgtttg cagctgattc atcgtcattg
    47101 tgccatatgg aagcatggaa accaagacgt aaataatgat caaaccgaat attcctagaa
    47161 tcgttgcttt cccaacatcc gattgttttt ttgctcgtga acctacgaca gaagctcctt
    47221 caataccaac gaatacccag agcatcacca tgatgcaact caatacttga ctagaaaacg
    47281 ggatcggctg cccattcgca ttcaatatga tatcgctaga aaagttatta atgaattgtt
    47341 ggatcgaaaa ggtgctgata gctactacaa taaataaaaa taatggcact aatttacaaa
    47401 atgtgacgat agcattgaca aagctagcat tttcaactcc acgattcact agccatgcat
    47461 atccccataa gaagatcgta ctcatcacga tcgatgccac attttgacca ccttcgaata
    47521 cggggaagaa ataacctaat gcactcatca acaatgttgc gaacgccacg tttcctaacc
    47581 agcatgtgag ccagtaaccc caaccgctga taaaaccagc gaaacggcca aaaccttctt
    47641 ctgcgtaact aaagatcccg ccttttaaat ctggacgttt tttattgata ttattgatcg
    47701 ataaggagag catcaacatt gctgttccta cgagtaccca gctgaagata gctgggccac
    47761 cagccgatcc ggagatgtcc gtcataatac caaatacgcc acctccaatc gctgaaccaa
    47821 tcactaaggc agcaagtgga atcaaaccaa ttcctttttt ctgttgctct gtatccatgt
    47881 aagcatcctc caaagtaaaa ccgcttttat caaaaagtat aacaaacctt ttttattttt
    47941 acttaattaa taaaaacttt aatagaaata taattctacc gacttttttc tcattataca
    48001 agcaaagcgc ctagtccctt tccaaattac accaccaaaa aaacttaaaa agatgctata
    48061 ctaaagggaa agaattgggg gatgatccat gaacatttta tatatatcga tttcaggaaa
    48121 tacgcgtgct tttgccaaac atctagcaga atatgctgaa aaaatgcatg cagaagatcc
    48181 tgtcaatcct gaagttactt taaaagaaat ccatgaaaat agtgatttta cgaaagaaac
    48241 agaaccattt tttactttcg ttcctactta tttagacggc gggaatgggt tagacaacgg
    48301 tgacacagaa atcttgaccg aaacgatgcg cgaatatctg gaatacgaag acaatcataa
    48361 actttgcctt ggtgtagtcg gtagcggtaa taaaaacttc aacaatcaat attgtctgac
    48421 agccaaacaa tacgcacaaa gattcggctt tcctttcttg gcagattatg aattacgggg
    48481 aacaccatct gatgtgacac gcgtttatca aattttggca gaaaaaaata aataacacaa
    48541 aagaagaagc tgaaaaataa atttcggctt cttcttttta tgttctctat tgtttctatt
    48601 cttattaagc tttgacatcc atcacaggtg cttttgcttt cgctttacct gttttttcca
    48661 agacaaagtt ttttacacga tccatattgg ttaccaagac gatcatggag gtttctttgt
    48721 ctgctgcttt gattgcttct aagtcagctt ctgctacaag cgtatcaggt gtcacttgct
    48781 gtccttctgt tactttcaca tcgaatggcg taccgcctaa gtcaactgtg ttgatgccca
    48841 tgtgaagcaa gatttctaag ccatttggtg tcgtaatgcc gatagcatgt tttgttggga
    48901 aaacagaact tattactcca gtaaccgggg aatagatatg tccgttttct ggttctacaa
    48961 agtaaccttc acccatcatt ttttgtgcaa aaactgggtc acttgcttta tctaaagaaa
    49021 caactgttcc gtcagcaact gatgataaga tagtcacact ttcagctgaa gcttgaggta
    49081 ctgctttttc aggtacttca tttactgtgg ctgtttcggt cgctagttct tctttttcta
    49141 aacggtcttt aggaataccg aagaagaatg tagcaacgaa gccaccagcg taagcagcca
    49201 ataaaccaag gatatagcct aaccatttac catcagagat caatggaatc aaagcggctc
    49261 ctgaaggtcc aatagcgatt gctccgacat ttccgatcat tccgatcact gccccaccga
    49321 tacctccacc gatacaagca gtaataaatg gacgtcctag aggtaatgtt actccgtaaa
    49381 tcaatggttc gccgattcct aagattccga ctggtaaagc ccctttgatc atttctgtta
    49441 attctttgtc ttttttgcag cggatccata atgccaatgc tgcacccact tgtcctgctc
    49501 cggccatcgc aaggattgga agcaataagg tacgaccagt ttcatcaatc atttgtacat
    49561 ggattggcgt caagatctga tgtagtccga acatgaccat tggcaagaat aatgtaccta
    49621 gaacgaagcc ggcaaatgct cctccaacac caagtaccca gttgatccca ccgaccatgc
    49681 cgtcagaaat gaaccctgct aaaggcatga tgaagaaaat ttcgatcaga ccgatggcaa
    49741 tcagggaaag agttggcgta acgatgatat ctaccgcatc aggtactact ttatgcagtt
    49801 ttttctcaac gattgacaat aaccaaactg cgaagataac acctaagatc ccgccttgtc
    49861 cagttgcaag agcttcaccg gtaaacaagt ttttcagtgg tgcttctgga ttcatccctg
    49921 tcagcatcac aacagccccg ataactccac caagcgttgg cgttgcacca aaaacttgtg
    49981 cagcattgat acctgtatag ataactagat agctaaacat cccgtttttc aagatgttca
    50041 tcacatcgat atattgttgc catgttcctg cgtctagtgt tccagctgtg actaagtttg
    50101 ctaaaactgc ggcaatccct gccacgatcc cagtgccgac aaatgcaggg atcattggta
    50161 caaagatatt agagatgtct tttaataccg atttgatttt agagggtttt tgtttcgatt
    50221 tttgtgccgc tttcatttct tgtgcccgtt cgtttacacg gtcttttcca gatgcagaag
    50281 aacttgctgt agttgcacta gcagaaggaa gtttttctcc taatttcacg cctgctaagt
    50341 caaccatttc ctgcgctact ttgttcactt tcccaggtcc gatgatgact tggagctgtt
    50401 catcctctac tacgccaagt actcctggaa tcgcttttaa ttccgagaca tttacaagat
    50461 catcattgat gaccttcata cgtacacgag tcatgcagtg gacaatgctt tcaacattgc
    50521 ccataccgcc tgctccttga taaatttgtt ttgccagttc ttccaaagtc aattcgtttt
    50581 ttgccatggt cttttccccc tcataaggtt ccttttacaa aaccgtttgc ttcagctaat
    50641 tttgcttgag ctgcctcttt atcactattt gtcaaaatca tgacgatagc cagtttgaca
    50701 ttttgatctg cttcctcaaa gtacttttca gctgtttcgt agtcagcttc tgtcgcttgc
    50761 atgatgattc gttttgagcg ttcaattagt ttttcatttg ttggtttgac gtcgaccatc
    50821 aagttattga atactttacc gataccgatc atactgatag tagaaatcat attcaaaatc
    50881 agtttttgtg ctgttcctga cttcaatcga gtagagcctg tcaaaaattc tggtcctgca
    50941 tcgacttcga ttgggaaatc cgcatgctcg ctgatttctg cttgtttatt gcaagaaatc
    51001 gttcctgtaa cagcaccaat cgattttgcg taatctaatc caccaatcac atatggtgta
    51061 cgaccgctag ctgcgatacc aataactata tcattttttg ttaaattcag cttgattaga
    51121 tcttcttgcc ctaattcata agaatcttcg gctccttcga cggctacagt cattgcttct
    51181 tctccaccag caattaggcc tatgaccatt tccggttcta caccgaatgt cggtacacat
    51241 tcagcagcat ctaatacacc aagtctacca ctcgttccag ctcccatata aatcaagcga
    51301 ccaccttttt taaaggattc aatcgtgttg gcgatcactg gctcgatact tggcagttct
    51361 ttttcaacag cagcggccac tttctgatct tctttgttca tgagttggac tgcttgagaa
    51421 atactcattt catctaatcc aaaagtttct tggtttctgc gttccgttgt taggttctct
    51481 aaattgattt tgctcatttt tatcttcctt cttttcttat aaattgatag ttcataccag
    51541 ctttgatttg gttgatcagc ggtagttctt ctttgatgac tttggctact acattcactt
    51601 tttcatccgc tggcaaatca tatttagtta attggatctc acccatatag cgcaaatact
    51661 tttcgttatc taaagtaata gatcctttca tacgcttagc tgtatttctt actgggattg
    51721 gcggaatctc tcgaaaacgc gcatctgcgc ttcgtatgac atctcttgca tcatcttgcc
    51781 gattcgtatg ttttcctaat atatattcgt aaaaaacttc atctacaggt tccgtatgga
    51841 gcaagactgt ctgttctttt tggaaagaag caaattgctc ctgaacgtgt tctgacagac
    51901 ctgcatctcc gatataaaca atatccgtgt tacttgctaa tagatcaaga gcacctgcca
    51961 gaggatggat ccctcgatgt tcttccaaag ttggtaatcc ttgatacagt ggacctctca
    52021 actctgtatc tcctggtaca aagccttgta caaggaatcc ttgagttttg agccattgat
    52081 ttttttcctg ataccattct ttgtccaacc ctgtttcaag acgtggataa taattatgcc
    52141 aagcttcaat ctgtgagaaa tcagccgctg cttctttcaa ctcatcgata tcattaggcg
    52201 tgatcgtgct ggcattcaaa ctgattttca attgatgtga ccagtcggcg atctgctgat
    52261 tagaaatatg ataatccatt cttaaccctg ttacaccaat tgctttcaag ggtgttagat
    52321 cttctaatga aaagccagct cgtttcaatg cctctcctga aatatcgacc atcaactcta
    52381 gtttattctt tttcgcttcg cttcctagtt cgatcaatcg attttgataa gccgaaacat
    52441 catcttccgg tatatgcatg gaagtgaaaa taccgacaaa gccattggat gccatttggc
    52501 ggatatactg tttcttctct tctgacaaag aatcattcat aaatattgaa aagccaaaca
    52561 tattatccct ctttttctgt atccgtcttc atttctatga ctagagtata tatctaaaga
    52621 aacaaaattt caatactttt gttaaaataa ttaaatttta tttctaaaaa ttggatttat
    52681 aatgccaaaa gaattgacac agccacaaaa aaggcactgc taagcaaaag cagtgccttg
    52741 aaacatttta tttaaataac acaaaagtct aattactcat aagaaattaa ttctgtattg
    52801 tctaccatga atgtaaagaa cccttcatta ggcattggat gaaaataagc attgatcact
    52861 cttatcaagg cattatgaca gactaacaag tagacatttt cttcgtcttc catgcattct
    52921 ttcaataaag gaacgatccg tgcgtacaca tctaagaccg actctccatt tgggaaacgt
    52981 acagcaaacg ctaaacgcgc tttttgaaag ttttcatctt tgcttggcag tccgtcataa
    53041 tccccaaaat ccatttctac caatcgctca tcagcggtca tcggcaaatt gagacgatca
    53101 actactgctt gtgctgtatc tcttgctcgt tgaagagggg aatggatgat tttcgtgatt
    53161 ggaacaggca aatctactac cttttctgct agtgcctgtg cctgcatctg tcctttttca
    53221 gtcagcggca catctgctcg cccgcaaact aatccttgtg cgttccaagt tgtttctccg
    53281 tgtctcgtta cataaagcat gtgattctct ccttcgttga caaagttctc cttaaccata
    53341 ccttgttgtc tttgagatta caaggtttag attttctcaa gagaaataat ctcagtagat
    53401 actttatcta gaaaggtttg atcatgttcc actagtaaca tagcaggttt cacgttcaaa
    53461 atcagttgtt ctaattgttc ttgattgaag acatccaaat aattcaatgg ttcatcccat
    53521 atatagagct cagctggttg ggataaagat ttagccaatt ccactttttt ccgttgtccc
    53581 atactcatct gttcgatttt attatgaaaa acatctcttt ccatcccaag ctttcggaga
    53641 ttattcaaaa atgcttgata gtctactcgg tttttcttcg cgaattccgc caatgtccct
    53701 cgattgtctt cataattttg gcgtacgtaa ctaatggtca aatgtttggg ctgggatttt
    53761 tctcctacaa ccttgccgtt gaatgtcccc agaagataat ggataatgga tgactttccc
    53821 gcgccgttag gacctgaaat tgccatccgc tgatgaggtt cgatcgtaaa atgaactggc
    53881 tcgaataaca gattttcata ccctaattga agattttcta cgcttaacag ccgtttatga
    53941 tgagacactt ggctattcat cgtcaaagca tcgatatact cgatatcttt taataatttt
    54001 tctttctcac tgatctgggt ttccatccga ttcacgattg ctttagatcg tttcatcgtc
    54061 cgtgcagcat cagcgcctac tgctccttta ttcactcgcc tagattccgt atcgatgaat
    54121 ccgacttttt tctttgtttt gtccccttct cgggaacgag accattctgc tttttcagct
    54181 gctgttttct ttagcctgct gacttctttt ttcaattttt catttttagc tatttcaaat
    54241 tcatcacgaa gttttttctg ttcttcatag atagagaaat tcccttgata aagttccagt
    54301 tggctctttt cgattgctaa aacatggtcc actacttcat cgataaatcc ccgatcatga
    54361 ctcaccacga tgaatccttg ttttttcttt ttcaagtaag ccgctacttg ttttctgcca
    54421 gagatatcca aatgattcgt tggttcatcg attaacggga aatgagtgtc atccacaaat
    54481 aagagtgcca gtaggacttt tgtcttctct cctcctgata gtgtgctgaa ttctctccat
    54541 aagatttcag gatctgtttg catcagttgg agctctcttt caatttccca tatctcaaaa
    54601 tccataatct catttaacac ataataggtc aaacgctctt tatcttttgt ttgctgcggg
    54661 aaatagacaa acgcttgctg atggatcact tgcccttgat aagggagttt gttttgcagg
    54721 atattcagta aagttgtctt tcctcgaccg tttcgtccga taagtcctag tttccattgt
    54781 gtgtcaaagt ttagattggc ttgttcaaat aataatgtgc cttggctgtc atagccgaat
    54841 gtcagatttt ttatttcgat tttagacatt attccatcac ctcgtaaaaa aagaccagtc
    54901 ctattttcag aactggctaa agaggatgca agggttgggg cacacaaaaa gacccataca
    54961 tcgaaagaac caagccaatc ccgaaaatct gcacactgct cccttgtctc cacaaggtac
    55021 agtctgaatg cagctttcat caatcgactt aatttttcaa tgcacggatc cctcactttg
    55081 tcctatattt gaaattacga tagcataaag aaattgtttt tgtcaactac ttcgggagaa
    55141 tgttgaaaaa tctgctgagt gtctgtccta agatttctgt tttttctaat gtttgcctgt
    55201 gttccattgc ttcctctaaa tcgattggtc ctaattgaat gcttaagaca atggggagaa
    55261 aatcaaagag tccttccagc tctcggtctc tacttccgca aatagcgatt attggttttc
    55321 gatatttttt tgcaagcact gctacgccat atggaacttt tccgtggatt gtttgctgat
    55381 caatccgccc ttctcctgta atgatgacat ccgcttgttc gatctgtttt tctaatccag
    55441 tgatttggct gaccaactca aaaccagaga ccatcttcgc tcctaacaaa aaaagggctc
    55501 cgccaatacc gcctgctgct ccgcttcctg ggatgtcatc taaatccacc tcccaaacat
    55561 cttttatctg ctgagcaatc ttttcagctt gtttatccaa gaaagctaac gtcgtatccg
    55621 ttcctccttt ttgtcttcca aattgccaag cagctccttg ttgacctgta tatgggttgg
    55681 tcacgtctgc agcgatgatc acttttactt tagaaacaag aacgttcctt cgatccaaat
    55741 gaagttttct agtagataac aaaggatttc cttctgtgta cccttctaaa gaagcaccca
    55801 aagattggag taatcctaga ccaccatcgc tacatccgct tcctcctaaa gtgacaatga
    55861 tttgttccac ttcttgaagc agtgtatctt tgataagctc tcccaaggca taactagaag
    55921 caagtcggat ggtttgatcc gttggtttat caagtaaatc taatcctaat acttgtgcag
    55981 attcaatgac tgcggtattt tttccttgcc agttcgtcaa taaataactg atttttcgct
    56041 gacgaaataa gagatccatc ccatcaatcg tacgccaggt tcccccgagc gcgtaataga
    56101 ttgcttctgc agtattttct ccgccatctg caatcggcac attgattttt cttcctttac
    56161 ggtcttccca accatttaga actgcctgat ttaattcaaa tgaagaagca cttcctttaa
    56221 atgaatcgat tgccgccaaa atatccatct atatccctca ctttcttctt aagtaagaca
    56281 ctttttttca cttttttcaa acaaaacaat gctattttct tctgtttttc tatatactaa
    56341 aagggaactc attgaataaa ggagagaaaa aacatgaaaa tcgcaatagc tggagccgga
    56401 gcaatgggca gccgaatcgg attaatgttg catcaaagcg gaaatgaggt cgtcttgatc
    56461 gatcgctggc ctgctcacat tgaagccatt cgtacaaatg gattgattgc tgactttaat
    56521 ggcaaagaag tagttgcaaa actgccaatc tattcaccag aagaaatcat cgaaagcaac
    56581 aaacacgtgg atttgatcgt agccttgaca aaagcgaatc aattagatga tatgtttcgt
    56641 tcgatccaat ccattattac tgagaatact tatgttttgt gtttactgaa tggattaggt
    56701 catgaagatg tactggaaaa atatgtacca aagaaaaata tcttatttgg gatcacgatg
    56761 tggacagctg gtctagctgg tcccggaaaa gtcacattat taggtgatgg agaaatcgaa
    56821 ctagagaact tggaaccaga aggcgaagca tttacaaaaa aagttgtaga agtctttcaa
    56881 gaagcaaaat tgaatccaat ctatagtcat aatgttcgtt attccatttg gcgaaaagct
    56941 tgtgtaaacg gaacattaaa tggattatgc acgatattgg attgtaatat tgctgaatta
    57001 ggtgcgcaaa aagcggcaga gggcatggtt cgaacgattg tatctgagtt tgcttctatc
    57061 gcagcaaaag aaggaatcac attagatcaa gaagaagtgt accaacatat tgcttctact
    57121 tatgatcctg acaacatcgg gttgcattac ccatctatgt accaagacct gatcaaaaac
    57181 catcgtttga ctgaaatcga ctacatcaat ggtgccgttt ggcgaaaagg acaaaaatat
    57241 gatattgcta caccatattg tgcctttttg acccaattag tccatgcaaa agaaggaatc
    57301 cttggcgcag aataaaaggc tctctgatga gaatcagctg gatcagcagc tggttctcat
    57361 ttttttaccc ccatgaaagt tcaaaaagaa aaacacaatt ctcatgttgc cataagaatt
    57421 gcgcttgttt attttcatct atgattggtt ggcactttta tttattttta acagaggaaa
    57481 gatcgtattc atattgttca taaatagcgg agtcagtagt gaaaaaacgt tttgcccaat
    57541 tttctgcatc aaaaaattcc aacagttctg atgggattgg ttgaaatggc gtatgcaaaa
    57601 attccggtaa ttcatctaaa tcacgttctt gaagcaaaaa aatattttca gaatgataaa
    57661 actgataatg agctatggct tgattatctg tcactagttt cttttgaaaa tacatagatt
    57721 caaacgttcg caaagtcact ccttgctgcc cttcccgcaa cagttctaga atccccctcg
    57781 attccccggt ttttttcaga tattcttcat aagtaaggta tccaggttgt tcatttcctc
    57841 gaagcggaag aataaagtaa ttggtcgtaa cacctctttt tgtaaattcc tgcttatatt
    57901 tttctgcccg ttcttttctg ccgttatttg ttgcaccaaa aaatagatcc gtctttggtt
    57961 cgctagaaga aaaatccata tgtttcgaat aaaaggaact attatgtttt agtccaagtt
    58021 ctttcgcttc taaaaaatca aaatgataaa tctcatcgat tgccggttca tcttgtgcct
    58081 gcttcagcat cgcctcgtgt tctgctttaa agtggttcca aaaaaataac acgatttttg
    58141 cattggtaaa tggacgcacg cgtcgagcca tctccatatc aaatccataa tctaaaaaaa
    58201 cgatcagctg ataatttgcc aactgttgtc gagctgattt aatgaattcc gactgtagta
    58261 aatcttttcc ggaccaaaca tctaaagagc ggatggaagg aaaaaaataa agtgatttat
    58321 ttttcgcaat tagcaatacg tcgtttttgt tcatctgttc cgcctcactt tctctgtcac
    58381 tttttcctat gatagcctgt ttaaatagta aaaagccagt aaaacgcttc ctattatttt
    58441 tataaaaatt taacatttct atgaaaatac gatgaaataa atcattcttc cattaaaata
    58501 tgcccaaaag ttttctgaat agttgtaatt atctgaaaat ttgttatcat tagtcattat
    58561 tattattact atttattctt actatttatt cttactatgc attttgattg tgaatttaaa
    58621 agaaagaggt tatttatgga agataaaaaa ttgaaaaaac aacttagctc ccgacatatc
    58681 accatgctag ctttaggtgg agcgattggt gcaggtctat ttaaaggaag tggcgaagcg
    58741 attggaatcg ccggcccttc tgtattgatc gcttttttga ttggcggcat aattttatat
    58801 atcgtgatga aaggtctggg aaaaattgtt ttaagtggtg gtgatacgca ccacggatta
    58861 tctggattga ttcgtccata tctaggtgct catgctgccg attttaccga ttgggtctac
    58921 tggtccatgt ggattatcaa tatcattgct gaagctgttg cagctgcttc ctttttacag
    58981 ttgtggttcc cccacatccc agcttgggta tttgttttta tgttggctgt tttaactact
    59041 atcatcaatc tttattcggt acgattattc gcagagacag aatattggct ggcctttgct
    59101 aaaatcagtg tcattatcct attgatcatt tttgctgctt atcttgtcgg tcagcaaatg
    59161 ttgggtactg gtgttttccc tacccttcaa caattaactg atcatggtgg ttttactccc
    59221 cacggtatga agggaatcat cagttctttg cttgtagtta tctattctta cggcggttct
    59281 gagttgattg ctatcacagt aagcgaagca gatgatccta aacgtgcgat tcctaaagca
    59341 atcaaaggcg tcatgggaag aatcatttcc ttttacatta ttcctttatt tttgcttttg
    59401 attatttttc cttggaatac tttagcaggc acgaacgtta gtccttttgt gatggtattt
    59461 gaaaaaatga atattccatt tgcggcagat atcgtcaatt tcgtgattgt tcttgctctg
    59521 ttctcgtcta tcaattcagg tgtatatgct tcttcgagaa ttttgttctt ccgcttgaaa
    59581 gatcggaaag gttcctctag aaaactagct gttttaaaca agcatcaagt accgcaacgt
    59641 gctgtgctgt tttgtaccag tgttctttat ctaggtgtgg ctctttctta ttttgtcggt
    59701 gacaaattat ttggctatct ggcaggttct ctttcctata cagtattatt gatctggatc
    59761 attatcagtg ctgcgtcctt tgtactgaca ctaaggaaag gaacgttatg ggacaaagga
    59821 atcagctttt ttgcattagc agtcttatgg ttgattttcc ttggtatcct attcacgaac
    59881 tccattgggg taactgtatt gaccggtttg ctttacctgt tcatttattt cagttatcaa
    59941 aaaaagaatg atgctttcgt cttgacgaat gaatgaaacc aatagagaat tttattctat
    60001 ttatattgaa tatctggagc tattgaaaaa aaggagctgc gacaaaaatt gttgcagttc
    60061 ttttttccga ataaacggtg ttcaaaaacc atctgtgcag attaattgat tgttctccac
    60121 gctcatgaca tgatagaaga aaggaatgaa gaaaaaggag tttgttttaa atgaaaaagt
    60181 attggaagtt tttgttgatg attggtgttt cgacggtagt catgtttggt atgatgtatt
    60241 tgaatgttta tgcgcttgat catatcttct tcagtcgcac acgtgtattc atggcgttga
    60301 tgatgggtgc agtcatggca gtcatcatgt tgttgttcat gtggaaaatg tatgaaaaca
    60361 aaaagataaa tgctatgatt ttagccgcta gtcttcttgt ttttgccggt tccttattta
    60421 tggtacgaag ccaaacaact gtcaacgata cggcgtggat gaaggcgatg atccctcatc
    60481 actctattgc tatcttgaca agtaaacgag ctgatttaaa agatcctgaa gtaaaaaaat
    60541 tagcggaaga aatcattcag gcacaagaag aagaaatcga caaaatgaaa aaaatgatca
    60601 aagaaatgga atgaccatta tccatccaaa taaaaaaaga ggatgttcca gaagtgatca
    60661 acttcaagaa ataagaagaa gctacttctg gaacaccgtg aatcagaggt tgtgaaaaag
    60721 ctgccctgca tcaagtaata agaacagcca aacaaaaata gcttctcata tttttcgttt
    60781 ggttaggctt attaccgcaa atgcaagctt ttgaacaccg tttattcgta aaagggagtg
    60841 tgacaaaagt cttgtcacac tcccttttta cgtttttatt gttctaattg cgctgtcttg
    60901 cttactgctt cttgcggttt cacaaatttc tttgagatcc cccaacctgt aaaggcactg
    60961 accatcgaaa acacaggtga aagcaaactg aaaaacacga atggcaagta agtgagtgta
    61021 ggaatgccaa atgtacttgc tacgaaactt ccggcgattc cccaaggcac taagtagttg
    61081 attactgttc caccatcttc tagtgttctc cctaatacag ttggatcaaa tcctgctttt
    61141 tcgtaagttt ctttaaatgc attaccaggc aggataacag atagaaattg ttctccaata
    61201 aagatattta ctccgatgct tgtcatcaat gttgtaaaaa tcaattttgg ggtgttcgtc
    61261 atctttcttg atactcgttc cataacggtt gagatcaacc caaattcgat caacaaacca
    61321 cctaatgaca atgttagaat aatcaatgac acagttggca tcatgctttc gattcctcca
    61381 cggctaagta gtgaatcgat ttgttggttt ccagtatttg aaacaaatcc cgattcgatg
    61441 acccctgcca acttcgttaa ggaagtttgt gggttttgaa taaagatcat tcctactgct
    61501 acagcaatat tcaacaaaat cgtcaaaatt gccggtacct ttttccatgc acacaagagc
    61561 attaaaaata gaggaatcag tgaccagatc gaaatagtaa agtttgcttc taaaatatca
    61621 gtcacttcac gaatagatga aagacttgcg gctttacttg tgtgtcctaa aatcatgaat
    61681 aaaaagaaag aaacaacaaa tgccggaaca gttgaccaca tcatatgctt gatgtgtttg
    61741 aacaaatcgg catcaacaat agctgctgct aaatttgttg attcggataa tggagacatc
    61801 ttgtctccaa aaacggcacc tgaaacaatg gctccaacaa caagggctgg atttagtcct
    61861 agtgttgtcc caataccgaa aaatgcaatc ccaatcgttg acataacagt aaaggcactc
    61921 cctacagcgc tacctacgat tgcacaaaca acaaatacag aagggacgaa ccactggaca
    61981 ctaatcaatt taaatccaat gaccatgagg gttggaataa ttcctgcttg tatccataca
    62041 gcaatcaatg aaccgactaa aataaaaata aagattggaa tgatccccgg tttgatgcca
    62101 ttgatgatcc cttcgtgcag ccaatctgtc gggtattttt ttatcactgc gtacaacatg
    62161 accattccga tagctgccaa aatcgtgata ttaggtgaaa cctttaatcc gacaacgcca
    62221 atcgcaatgc ctaaaacaat gaccatcaat acaagtgttg cttctaaaaa acttggtgtt
    62281 cctttttttt ccatgataat ctctcctttt ttagttgttc ttatgttcta aaaaagttaa
    62341 gatatcggat tactccgcca caattcatcc gcgattcctc ctttataaaa ataaaaagac
    62401 ctgctttcaa ctaaggacga atgactccgc ggtaccacct taattaaaaa cagatctgtt
    62461 tttcactttc aaacgattat tcaaatgtat ggactttcca tgtaattcgt caattaggct
    62521 tgatcggttc acagcgacca ccgactttct gaacaaaaca cctaaccact actgcgtgaa
    62581 aagttgactt gtatgaagtt taccttccat aagatcattt gtcaatgaaa aagaaaatat
    62641 tttttcattt ttctgaaaat tatttttata actttcgcgc acaactttat ctttttacta
    62701 gaaagtagcg ccctcttgtt tttttcttgc tactatttct tgatgttctt gtttgatttt
    62761 ttctaatagc ttgggttctc tcaataaatc tagagctgta ttggcaagta attccgctgc
    62821 aatcgcaata gaagcaagtc ctttttcact tttagcagca gctttgaatt cttctgtatg
    62881 tccggcaata tatgtctcag agattgctac agtaggctgt atcgttggaa taacttggct
    62941 aacatttcct acatcagaag aacctagact tgttctttgt tccgtttcta tttcttcatc
    63001 aggaacccct gcttcttttg catgttggaa gaataagtca tcgaaagaag gcgttacgat
    63061 gacatcatcg actgcatttt ggaacaatcc aaactcaaaa gtcgtacccg tgcttaatgc
    63121 agcacctcgt acgatatttt ccactttttc atatactttg tctaatgttt gtcgatttcc
    63181 tgcacgtaaa tagaaacgtc cagcagcgta gtctggtatg acattggccg ccacgcctcc
    63241 atctgtaatg attccatgga tattgacatc ttttggcaat tgcaagcgta gagcgttgat
    63301 tccgttaaac acttggatca aggcttccaa agcatttact cctttttcag gtgctgctgc
    63361 tgcatgagaa gcgacaccgt aaaatttgat atcgactgga tcatttgcta aagattctgt
    63421 cgttttccca taacgaaaag ctggatggac acataatgct gcatcgacat cctcaaaaaa
    63481 accttcccga acgaagcttc ccttagctga tccattttcg cctccttctt cccccggagt
    63541 accatacaca cgaatttctc cgccaatctc atcaatgaat tgtttcacta tgctggctgc
    63601 taatacggag taagtaccaa ataaattatg tccgcatgca tgaccaatac ctggtaaagc
    63661 atcaaattct gccaaaaagg caattgtcgg acctggttta ttggaaatat aacgtgcatc
    63721 aaagcctgtt cggtgcccag ctacttcttt ttctacccag aacccttctt tttccaattg
    63781 tttgattaaa gctgctgagg aataaaattc ataattactt acttcaggat ggtcgtggat
    63841 agctagtgca agtgcttgat attctggtaa acggtattga atcagatcct tcaattgatt
    63901 tgttgagagt gtggttgtca taaaaatttc ctcctatgct agtcgttttt tcttattttc
    63961 tcccgaatgt ttcccacgca ggtacgcttg aaccttttga tgttttttcg attactttgg
    64021 ctgtttcttc tgtttgatag gcatctacta ttttttgata cgttttattg tcttcatctt
    64081 cttttcttgc aacgatgata ttgacataag gacgtgcatg ctcatcgact ggttctaaga
    64141 agattgcatc agaagcggga ttaaatccag catctacagc tacaccgcta ttgatgactg
    64201 aaatatctac atctgacaaa gcacgtgctg tttgggaagc atctaactca gaaatgtcta
    64261 gatttttttt attctcggta atatcagaaa cggtaggcgc ttggcctttt gccttgtcca
    64321 ctttgatcaa tccagcagtt tgcaataaca gaagagctct gccgccattc gtgacatcat
    64381 tagggattgc aacttttgct ccatctttga tatcagccac atcttttaac gtattggaat
    64441 aaattcccaa cggtgcatta accgtattcc caatcgatac taaatcagtt ccgtgttctt
    64501 cattgtaatt gtctaaaaag aattgatgtt ggaaggaatt caaatcgatc gatccatctg
    64561 ctaaagccgc atttggctga ttgtaatctg taaatttcac atattccaaa tggatgtttt
    64621 cctttttcaa acggtctttc acatcgtccc atacatctgt atcttcccca atgatcccta
    64681 gttttacggt cgtttctttt ttttcagttg tagctgcttt tccttggctg catcctgcca
    64741 accaaataat tgctacaaat gtaatgactg caaaacgaat aatttttttc attttttctc
    64801 ctccattttc aatgtgtgac ttttttaatc agttgattac tgataaattg actcaaaaaa
    64861 actaagacca gaatcaataa tgtagcgaca atcgttacat ctgtttggaa tcgattatat
    64921 cctctcgata tagcaagatt ccctaatcct ccggcaccta ctgctccagc catggtagtc
    64981 agtccgatca cattgatgat cgtcaacgct gagacccgaa tgataccagg taacccttct
    65041 aacaaataaa cacgtaaaat gatgccgatt gggctcgtgc ccatcgcttc tgctgcttcg
    65101 atcaccccag gatcaacttc tagcagtgca ttctcgattt gacgggcaaa aaacgggaca
    65161 acgccaaaaa tcaaagggac taaagctgct ttggcaccaa tcgtcgttcc aactaagaaa
    65221 cgagtagtca aagctaaaag agaaagcaag ataatgaaag ggatggaacg aatgatattg
    65281 atcaacttat caagtatttc gaacagcagc ctgttagcta gtaatccatt tggacgtgtc
    65341 actactaacg tcacacctaa gatgattccg atgatcccac caatgaatgc cgtccaaaaa
    65401 gacatatata gtgtttgctt tgtcgcttcg atgaattcat ccggaatcaa atagacattc
    65461 ggcaaatatg ttttaaaaaa ttcagtcatt ttagtttcct ccttcgatga ctttgatacg
    65521 gttatctaat tcattttttt gtaaaatagt tacttttaca ccagatttaa tcaaataatc
    65581 caatgctttt tgccgctgtt tggtttctcc agctaaagta acgatcaaac ttcctaaggg
    65641 tgtttcttgt aatagctcta cattaccgta taagatattc gctgttactt ggtacttgct
    65701 gtaaagatga gcgattagag gttcgttcgt ctggttgccg atataactta attccaccaa
    65761 ccatttattt gcaatctgat cggcaaaagc agcatgggca ctgattgttt ccaatgcttg
    65821 gtcaaggtgt gtcgctgtcc gaataaaatc tttagtcaat tcttcttcag gatgactgaa
    65881 aatctggatg ctgctacctt tttcaatgat tttccccgct tccataaccg ctaccttgtt
    65941 gcagatttct ttgacaactt gcatctcatg agtgatcagg acgattgtta gacctagctg
    66001 acgatttagt ttttttaaca gtgcaaggat ctgaagggtc gttttcggat caagtgcact
    66061 agttgcttca tcgcataaca acactttagg ttcatttgcc agagctcgtg cgattgccac
    66121 tcgttgtttt tgcccccccg acagttgttt aggatacgca gatgcttttt cttccagacc
    66181 gacaagttcc agtagttcat tcactttttg acgacgttcc tgttttgatt ttccagaata
    66241 ctttagagaa aaatctacgt tgtcaaaaat cgttcgactt tccattagat tgaaatgctg
    66301 aaagatcata ccgatggcct ttctttcttt tcgcaattct tttggagaga gctggcttaa
    66361 attcgtctga ttgacgatga cttctcctgc tgttggtttc tgcaacaaat tcatcacgcg
    66421 gactaacgta ctctttcctg cacctgagta accgacgatc ccataaacat cccctttttc
    66481 aatcgttaaa tctacagaat ctactgcctg tatctctttt tctttttgtt tgaaacatac
    66541 agaaatatct cgcaattcaa tcattaacat tcctccttgt ctataaaaaa agcatcctca
    66601 agaaaatgaa aatagtcatt ttcttgagga cgcctttttg cgtgttacca cctcatgttc
    66661 aagctgtgtt cacacacaac tcctcttcaa gtaccatcat actctagcaa gatatcggtc
    66721 gcagccgtca ccgccttaca tctatgctcg ggatgaattg ctcgatggcc attttccaat
    66781 agtcgttcct tgcttcttct cagctaccga agctctctgt caaaggttct tctatcgtac
    66841 ttaccatttc aatgcaaata atattcaaaa aaaaaatcct tttactaaca taaactatgt
    66901 cagtaaaagg acgacgtatc gtggtaccac cttttttcgg aagtttcctt ccctcaagcc
    66961 caacatctca aaaagagaga ttggcgttcg ttttaacggt cgaacatttc cgaatttgcc
    67021 tacttatcga caaattattc tccaaggcca ttttcagctt ttcttacttg actcttcaca
    67081 ccagccagag cctctctgca aagtttccaa gcttactttc cttctcaacg aaatcaatat
    67141 tttgttgttg ggaataatct acaggaggaa aactgaaaag tcaagcatga aatccaaatt
    67201 attttttcta tatttatttt tctgtttttt tatctaacat ttcaataaca gttcgaagat
    67261 cttttccttc cgcaagaagg ttcaattttt ccttctcttc gacgctataa tttcgaacaa
    67321 aactggaatc gggaatcaaa acaacgccta gtcctgcacg tgaagcggct gtcgctccta
    67381 ctaaagaatc ttccactgca aaagctgaaa gagcttctaa tcctgttcgt tccaaagctg
    67441 tcagataagg gactggtgaa ggcttgttct ccgatacttc atctccgaac gtaaacgtat
    67501 caaagtaatc ggctaattga aagtgatcca agatatctgt tgctcttttc gtaacagttg
    67561 tcgtagcaat ccctagtttc atatgacgtt cttttaagtc tgtcaatatt tcttttgcat
    67621 agggtttcaa ttggatagct ccacttgtca gctgttgata aaaatattct tcacgctttg
    67681 ctcggacttc ctgcactttt tcaggactgc ctgctgcctg cactaaaata tcaaaacttt
    67741 gtttccagtt ttttccgccc caagcgtcaa cgatttcttt cgggatatga atatcaaatt
    67801 gctggaatcc ccaaagccaa ccatcccgat acgttctttc cgtatccact aacaaaccat
    67861 ctaaatcaaa tattgcacct ttcatctata ttccaaaaca atacacctag tttagcatga
    67921 ctgatccaaa atgaacagaa gcatagagcc cagccgcatc acttataaga gttcttggaa
    67981 tcgacggata tagattttct tcacagctgt cacaagcgcc agataagcga cgactgttat
    68041 aaacaaccat aaccagtaat tgccagggag cggcatcaag cctaactcag caccaaatcc
    68101 tgtgaatgga aggactgaac cgacaatgat tcctaatgta gtgataacca gcatggcaaa
    68161 tgttgcattg ctttggataa atggtatttt cggtgtacgc aatgcatgga gtactaatgt
    68221 ttgtgtccac agggattcga caaaccatcc tgcatggaat aatgcgataa aaatcacttg
    68281 ttgtgagcta tccaatgtat ggaaacttcc accaactaca gcaggacaaa taacaaaata
    68341 catcaacaag taagtagtga tatcaaaaat cgaacttgtt ggaccaaaat aaaccatgaa
    68401 ttttccaata ctagatgcat tccatttctt tggctcatcc aaatattctt tatccatccg
    68461 atcccatggt aaggaaatgc aagaaacgtc atagatcaga ttcaaaaata gaagttgcaa
    68521 aggcaacatt ggtaaaaatg gtaagaacgt actggcaatc agtacggaaa acatattgcc
    68581 aaaattagaa cttgctgttg ccttgatata tttcatgatg tttccaaaag tttctcttcc
    68641 agaaagaagg cctctttcca aaatcgtcaa atctttttct aaaaggatca cgtctgctga
    68701 ttcttttgcg atatccacag ctgtatccac ggaaataccg atatcagcca ctttcattgc
    68761 tggagcatca ttgataccat ctcctaaaaa tccgacagta tgcccatttt tacgtaaagc
    68821 tgtcgtcaat cgtgcttttt gctgaggatt caattttacg aatacttcgt gttcttcagc
    68881 tacttgcgct aattcatgat cattcatttc cgagattttc tcaccagtaa tcaattcatt
    68941 gatttctagg cctacttgac ggcacacaga ccgtgtgact aattcattgt ccccagtcag
    69001 aacttttaca gctacaccat gttcttttaa agctttcaac gcttgttttg ttgtttcttt
    69061 tggtggatca aggaaagcaa gataaccaat cagaaccatg tctgactcat ctttgactga
    69121 aaattctcca acaacgcttg gattggtctt ttgtgcgaca ccaatcactc gtaagccgtc
    69181 ttcattaagt gattgtactt ttgcaagcac cgcttctttt cgttcttttg ttaatggtgc
    69241 gacagtacca ccaagatcaa taaatttaga aatgttcaac atttcttcaa tcgcgccttt
    69301 tgtgatcatc tgtgttttgc cagccggatc agcgactaca acactcatac ggcgacgttc
    69361 aaaatcaaaa ggaatttcat ctactttttg ataattgatt gtatctgtat ctaaagtttc
    69421 tgctgcttca tcaatgatag ccacatctaa caaatttttc agccctgttt gatagtagct
    69481 gtttagataa gcatggcgca aaacacgatc atcttcattt ccttcacaat ccatatgata
    69541 ttcaagaatg attttgtctt gtgtcaatgt tcccgtttta tccgtacata acacatcgat
    69601 cgcaccaaaa ttctggatag catttaaatt tttgatgact gttccttttt tggccatcac
    69661 acttgctcct ttgaccaaat tcgtcgtaac gatcattgga agcatttcag gcgttaaacc
    69721 aactgccaca gataatccaa aaagaaaagc ttctaaccaa tctccttttg taagcccatt
    69781 gataacgata actgctggag ccatcaatga cataaatttg atcagcagca tggatgtttt
    69841 gtggatgcct aattcaaaac ttgattggat gggtttttca gatagcgttt ctgctacatg
    69901 cccaaatagt gtgtcatttc cgacagaaac aatgattcct tccgcgcttc cactgatgac
    69961 attgcttccc ataaagacaa gattttcata acttgtttca ctttgctgat cgtcttcaca
    70021 tactttcgca tgcttttcta ctggatagct ttcccctgtc aatgctgctt gagaaatgaa
    70081 tagatccttt gcggacaata aacgcatatc cgctggtatc atatctcctg ctgaaagccg
    70141 aacaagatct ccacagacga tttcttccat aggaatctct gtatactcgc catttcgttt
    70201 gacagctgcc gttactttca caagtgattt cagtttttca gctgcttgat tagaacgcac
    70261 agactggatc aacgtcatcg tcccactgac gataaccata gtgaagataa tggctacacc
    70321 aaagagatct ttatctcctg gagcggctaa tacgtattcc gtaatgaatg aaataattcc
    70381 taatgcaatc aacactaatg taaagggtgt gatgtatgct ttcaatattt ctataatgaa
    70441 tggtgttttt ttgccatatg aaatcgcatt ttcaccataa gtttctcttg aacgctcgat
    70501 ttgttcttct gacaatccat ttggtgatgc atggaacaat tcaaataatt cttgcttcgt
    70561 ttttccagca aaagctgcat agattttttg tgtatctttc tttttttcca tctcgatctc
    70621 tcctttgtgt ccaaaagaca gctgttctcg ctgtttttgg tcttttgcta ttcatcggat
    70681 cgatagagaa aatgctgaaa ggggctgaga acagatagat aatagccctg gcctttcctc
    70741 taaatccttg tttttcgaat gactgtcatc catttgttct catctccttt actaagtaat
    70801 tttaattcat gacttccaat catttttcga atagttattt tcccaactcg ctcacctccc
    70861 tttttgtttt ttcacctatg ggatttgcgg caacaaaaaa acctctcgcc aaatactcag
    70921 cgaaaggttt gaaaaagcaa atcaaaaaaa gcttctcaga tctcatcgtt gagttttgac
    70981 actgtacaac gtaaaaagca gatatctgct tttagctacc ttatgaaaag ccttatctcg
    71041 acaattcctg ttctacccat tggcgtctct cgacgttttt gggcagtagc ctatgtttgt
    71101 ataggagcct cacctaacaa atcctattcg gttttccctc gttaatataa caactaaaaa
    71161 agaggatgtc aaatcaattt tccatgtttt tcatactttt ttaaaataca cgcgttatat
    71221 ttcctgtctc acgcagtttt atttgtctca ttttccacct cccgctataa tagaattata
    71281 gtaggaaacg aggtgctgtt atggaacgaa cacttgttat tatcaagcca gacggcgtaa
    71341 gacgccattt ggtcggaagc atcatccaac gttttgaagc aaagggactg gccattgctg
    71401 aaatgaaatt tgcaacgatg acacctgaac tagcaaaaga acattatcag cacttgactg
    71461 aacgtagttt ttttgatgag cttatcgatt acatgacttc tggtccggtc gtttatcttg
    71521 tgctggtcgg cgaggaagtg atcgatatcg tccgtaagat ggtcggagca acaaaagggg
    71581 cggatgccgt tccaggtacg atccgaggag attatgcact gccggggact gaaaacatca
    71641 tccatgcttc tgattcccgt gatgctgcaa caaaagagat cgcccgcttt ttcccgccat
    71701 tcgatacaaa caaaccgtct gaaaaagcgg cgaagtgata caaatcctaa actgttggtc
    71761 taactgctgg gtttagcaat ggccagcagt tttttctcta aagaattcct ttgattcttc
    71821 cctaatgtat attcgatcac tgcgaaaaac tcttggtgat tttccgattt ttcttcccct
    71881 aaagcagcag aaatcagtcg ttggtaataa tccgccatca atgtttcata aatcactgta
    71941 cttctttctt tatgcgctaa actccgtttc atatcttcat tcacgctacg tgcctttttt
    72001 aagcgaccat tttctatata aaacaaagtc aagttcgtca aaaaagtaaa gagatactgc
    72061 tcgtgattat tcagttgcgc gatccgtcgc attctttttt tgattttcaa ataattattc
    72121 tcaataaaac gatcactgaa tatccaagga aaatctgcta gaatagatac ttcaaattgc
    72181 ccatactctg gtacttgcat caaatattct tcaatgatac gacattcata acgcaaaaat
    72241 tcaaattccg tctcagatac ttctgttttt ttggacatgt gcagattcaa aaccaaatag
    72301 tacagatctt ctgttttctt atagtgcctg cggttattag caatttcttt gtaaggatca
    72361 aagctgtctt cttgaatccg atctagcatt cgtctttttt tctttaattt ttttggctca
    72421 tcaagctgat ttcgtatcca ttcatattcg gcaagtgtca tgttcattcg ctctaaaaat
    72481 gatttcaatg ttccaaacga tacttttttc actgaatttg tctcgatccc gactagcgaa
    72541 gttttagaac agattccttc cgctaattgg gtctgtgtca gctttttgtt gactcgaagc
    72601 ttcttaatca attctccatc atacataata gttctccttt tttaattgaa attaaccctt
    72661 ggcttttcca gaatgcttgc caataagagg aatgattatt tcaatttaaa ttttccgcat
    72721 tcaataaata gatacgttaa aaataaaaaa tacacgaaaa aaataaaaaa atgtttttct
    72781 cataaaaaat accaaccttc aagcatgaga ctgctgtcta atccctgaag gttggtttga
    72841 ttgtttattg atcatttttt tactgctccg cattggttcc tgttactgga tataggatag
    72901 tcgttgtttt attgccgttt tttgaaaaga cactggtcga atgttcacct ttttgctttt
    72961 cgattgcttc attacgttcc gcttcgtttt tatagtcata ttttttcgga tcaatcgtct
    73021 caaatccgtt tggcacataa aaccgcaaga gattttcctg attcagctta tctgaaagac
    73081 ttaacgcagt cttgactttt tcctgatctt tggagatttc ctcgtcgatt cctgctgctt
    73141 tcgtatcgat gatttctcct gtctgattat tgtaagcttt tcctcctagg acggtgtatt
    73201 tgggcgtcac gaagttccca tttcgaaaag caactacttg atcgtgctga gaagataata
    73261 agtctgtacc aaaatgaaga taatctttat catcgattcc caatagatgt agtaatgtcg
    73321 gcaaaacatc gatttctcca ccatattcat gattgactgt ccctttagtg taaccaggca
    73381 tatggatcat caatggcact cgttgcatct gtgcgttgtc aaattcatcc catgtatctg
    73441 gatctttacc aagagcactt gctaaatctt tattatctgt attcgagatc ccaaaatgat
    73501 ccccgtaaat cacaaagatt gaattttggt aaataccaga ttttttcaaa tacgtaaaaa
    73561 attgttccaa tgattgatcc agataatggg ccgttcgaac ataattatct actgtgctat
    73621 tgccagtatt caaagatgga aagtcgaaat tcttgtcatc cgtataataa ggcgtgtggt
    73681 tggttacgga aagaaatttc gtgtaaaacg gctgttgtag atgttcaaga tattgggcag
    73741 attctctgaa taaatcttta tctaatatcc cataacctaa cgtttcatcg gattcatcaa
    73801 aataagatcg atcaaagaaa ttgtcatacc ctaaattttt atatacatga tctctattcc
    73861 agaaactagc tacattccca tggaaaacag cacttgtata gccttctgtt tgaccaaggg
    73921 tcgctggtgc tgcttgaaag acattatctg acccaagttc tgtgaataat gagccttgag
    73981 gtaaaccaaa tgtgccagtt tccaacatgt tttcagcatc acttgtcttt ccctgtccta
    74041 cttcatgaaa gaaattgtca aaactgatcg ttgcttgatt ctggaaaata ctatttaaaa
    74101 acggcgtgac ttcttgtccg tctaccttca tattgatcaa aaactgttga aaactttcta
    74161 aatgaaggac aatcacattt tttcctttag caatcccaaa tgtttcagga tttggctctg
    74221 cataatgttt ctttgtatag tctaaaactt catcaattcc attactgctt gcatgcgcgc
    74281 gaacactgct agtcattcct gttttgattc cgtcataaat agtgtacgca tcgattccta
    74341 gatatttgac aatataggaa cggtcaaatg tccgctgtag caattgggga cggttggctt
    74401 cgctcaacgc taaatttcct gaaaaaatca atcctgaaag acaggtaaca gcgatagcca
    74461 tcggtttgct gacagggttg cttttgatag gtattttctt gaccttcaac caaaccagta
    74521 gcccaatgaa cacagcgata tccaaccaat agatgacatc atggggtttc atcaaagaaa
    74581 aggagcttcc tgacaaccct tgtgacactt tcgaaaagcc taatacagat ttgactgtaa
    74641 tgaaatctgt gaattcccga taaaaaataa tattcaagta caacaaaagc gtatttaaaa
    74701 tatcaatgat caaaagaatg gctaacgctg gctttggctt tttaatatac aaagaaaggc
    74761 caaaaaacaa taaggtagtc gcaatcgggt tgatccacaa gataaagtac tggatcgtac
    74821 cttccacacc taatgaaaaa tctgcatagt aggcaatgat cgtcttcagc cagaaaaaga
    74881 aaacagctgt caaaacgatt gctaaacgat tttggcacaa ttttttaagt tgtgtcacgt
    74941 atatcacttc tctctattca cattttttct tattttgctc ctgaaaaatg aaaatttcct
    75001 aaaaaagttg ttatcttaag atttttttat tctttctaaa gattattcca ttcatttttc
    75061 acagcataaa atcgtttcgg tgtaagcggt taaaatagta aggagataaa aatcttgtgg
    75121 tgaccgattt actctatagt attcaaaagt agtttctcgg tattcgtaca aaaaaaacat
    75181 actaagatta gaggggaaca tcattgacga atgatgttct cctctatttt ctatttttag
    75241 attatagtga agagtgaaag aaagttcgaa caaagccttg aggactacga gtccctatca
    75301 aaaaccgaac ttctttactg tcattttaga atcaggttta cgtatgttgg ggccatgagc
    75361 ccgtgtatag gaaattggaa tcgaaatgaa gcagtaaagt tctttcaaca cttaaaaagg
    75421 aggaaaacaa atgccttaca ttcttgcatt agatgtttca atgggacaca gctacagtgt
    75481 cctatacaaa gacgacacct gcttatttga agacgagatc gaacacactc aaagaggatt
    75541 tcatgcatta ctcgaagaga tccagcactt gcctgaacgt ccattgattg tttttgaagc
    75601 aacgggtatt tattccagac cagtcgaaaa gttctttcaa gatcatcact tttcttactg
    75661 tttgttaaac ccgttagaag cgaaaaaaca gatggaagaa aacaccttac gcagttggaa
    75721 aacagataaa tcggatgccc atcggctcgc acagactcat cttaaaaatc aacgtcaacc
    75781 aaaagaagta caaagcaatt tttacttaga gatgcgcgat ttagcccgtt tttatcaaga
    75841 aattgagaag aaaatcactc gactgcgcat ggatttacac aactgccttc agttgacttt
    75901 tccagagctt gaacagttct tttcaaacag gctgacccct tacgcattga cattgatccg
    75961 tctttttccc catccagatt ttgtattggc atctactcgg acaaaaataa aaaataaact
    76021 gatcaacgaa acacgggaaa aaatctccgc gaatcgtgcc gagcaaaagg cagatcaaat
    76081 catccactat gcacagtgtg cctatccagc tgttgaaaaa gacagtattc actgtcaaaa
    76141 aacgatctat tacgccgaac ttctccaaga tttactcgaa caaaaaaaag cactggcgac
    76201 acaaatgatc aaaaaagccg aagcctctcc ttgctttttg ttgtaccaaa cgttccctgg
    76261 gattggcgca ctcacagccg ctttattgct cggtgaatta ggagatatca cacgatttaa
    76321 aacccataaa caattgaatg cctttgtcgg aatcgacatc cgacggtatc attcaggtaa
    76381 gtatactggc caagaccgca tcaataagcg tggtaatccc aaagcacgga aaattatttt
    76441 cttcaccatt cgaaatatga ttcgccagca acgcgcagct cctaatcata ttgtcgatta
    76501 ttactacaaa ttaaaaaagc aacctatccc taagaaagat aaggttgcca cagttgcttg
    76561 tatgaacaag cttctgaaat gtatgcacgc tatggttagg gcacatacag agtacgacta
    76621 tgcgtacgcg gtctcagtgg accattaact aaaccactta cagtatacca cttctttgcc
    76681 cagatcgaaa attttttacg aacggggctt tatttagtgt gccttgattt tgtcgctttc
    76741 gtttacgagc tatttttctt gcacctttta cttgactaat cgtaggaaag aggctgtgac
    76801 aaaattcttg tcgcagctcc ctatttcttg atgcaggaca gctttttcac aacctctcca
    76861 ctaaacggtg ttcaatcagc tgaccttcgg tattagctca aaaaacggca aaatatgagg
    76921 agctattttc ccgttttttt ctctaatact caggtcaaac cgctgatttc acaacctctg
    76981 attcacggtg ttccagaagt agcttcttcg gaaataagcc gaaattttac aaaaacttga
    77041 gaagcacttt tcgtaaattt cttcttattt cttgaagctg accacttctg tcacaacttc
    77101 tgtttttcat tgtccatagg tttgatattg tccttctgat gactcattcg taatgattga
    77161 ggcttgattt tcttcatttc ccgttatcgt ttgtccactg ccagaatctg aagggcttag
    77221 ttctgtcgac tcgttttttt gagaagaagc agttgttttc ttgacttgtt cgttggtctt
    77281 tttccattcc gctagtcgat cggccaccac ttttttgtcc actttttcag aataagctgt
    77341 aaccactttt ccatttttca aacgtgctac cttgtcgcca tcatgagtca aaagcaaaac
    77401 gaccaaatgt ttgtctttga attgatattg tctgagagaa atcgcactaa gtacgtcatc
    77461 gatattgata aattgatttt cttcttttcc ttttggcaaa tagatgtcca attcaccttt
    77521 ttcgtaattg gcagttaatt tatattcctc ccaccaataa gttgagaatt cttttttgaa
    77581 attatctact gattctttgc ttgctacgat tttttctgtt tctttctgag caagatctgc
    77641 tgtcattttt cctgaaaatg ctgcggataa aataagcagt aagaaaaaac cgaataacca
    77701 aaagagaaga aacggtcttt ttttcctcat gccttcctcc actcctattt aattttgact
    77761 attctattat atacaaaaaa tgaaatagaa agacaaaaaa gttgaaaaag atcgtaaata
    77821 attgaacttc tttttcctga agcggtaaga acgggaattt tcatacattc tctcttggct
    77881 attctttaag cttcaaatcc atttctgtct gatacatctt tgaaccaatg acccgatttc
    77941 ttgatcgttc tttttccatc ttgtgctaaa tctactgaaa taaaaccgta acgattctta
    78001 taggcattgg tccacgacca gttatccatg catgtccaca tatgataacc taaacaattg
    78061 gcaccttctt gaatggcttg atggacatat ttcagatgag attgaacaaa ttcgatccga
    78121 taatcatcgt ggatcatacc atcttccttg ataaatcgtg cttcattttc tacacccatg
    78181 ccgttttcag aaataaaaca gtcgatattc ccataatgat ctcgtacatt gatcaaaata
    78241 tcatagattc ctttttcata gatctcccat ccgcgataag gattcatttt acgaccaggc
    78301 atttcataat tgtcgaagta atcctcaggc ataggaccgt ttttagtatc gattggtgtt
    78361 tcttttgctt ttattcggcg tggttggtaa taattaattc ccaaaagatc tactgtgttt
    78421 tctttaatga tcgtcaaatc atctggatga atctccggca ttagatcgag ttcttttatt
    78481 ctctcaatca attcactggg aaactcgcct tttacagctg gatcaaggaa tgaacgattg
    78541 aagaacgcat ctgctattcg tgctgcttta acatcttcgg gatttgattc gtctcttgga
    78601 taactcggtg tcaaatttaa gatgattccg atcacaccgc tttgatccat ttcatggtaa
    78661 gctttgatgg ctaatgctga agccaacgct tcatgataac caacttggat tgcctttttc
    78721 atatctgatt cttccggata atgccatcga tacaaatagc ctgcctcgac tggaacgatt
    78781 ggttcattat gggtaaacca tttttttact ttcgagccaa acaattgaaa acaacttttt
    78841 gcgtattttt cataggcttc aaccgtttct cggttcaacc atccgccttt ttcttgcaga
    78901 tacatcggca tatcgaaatg atacagatta acaaagggtt cgataccgtt ttcaatcaac
    78961 tcatcaaaat agtgatgata gaaacgaacg gcttcttcgt tgattgttcc agattcatca
    79021 ggtatcaaac ggctccattg gatagaggtt cgaaatgaat tatgcccagt ctgtttcatc
    79081 aactgtacat cctcttgata cttcgtataa acttgcgagg ttttttcagg tcctacttga
    79141 tcaaagaact tttgcggttc gtttttgtac caataatcaa aaatattctc tccttttcca
    79201 tcgcctgaaa ttcttccttc tgtttgtgga ccacttgctg cagagcccca ccaaaaattt
    79261 tttggaaatt gatatctttt catcaaagca cctctttttc ttttttagtt gattccatgt
    79321 atgatatttt ccatcacaat cactttttca ttttcttcct cttctttttt gattcgtttc
    79381 aacagctgtt ctgctgctcg ttccccgatt ttatctgttg gtggcgtgat cgtgattttt
    79441 ggaaggatac tcagatcgtt tttatctaaa taatcatagt gactgaacgc aatatccttc
    79501 ccgattctga caccttcttg attgaaacat tcgatggcac caatcgacat gttgtaattg
    79561 ctgacaaaaa tagcagttgc ccctttttct aataatgctt ttgccccgta atagccgctt
    79621 tttctagaat agtctcctgt aaagatctct aaatggatag acggatcctt ttgtaccgct
    79681 tctttggctc cagctaaacg ttctcttgct acgtaatctg tttgagcggc agcaataaat
    79741 cctattgttt tatgtccttg tccgccatga tgagcaatca cttttgctac actttctcga
    79801 tcattcacta ctattgtatc aatacctgct ggcccacccg gacaattcaa tgcgacaact
    79861 gggatactca tttttgtcag catttcaaat ccagaccact cttcttctga taagaagacg
    79921 atcaatccat cgatcgcatg cttcatcagg tattcgattt tttgttcgat tttttctggc
    79981 tgatcggcaa acccgcttaa taataagcta tacccatttt cttcagctac tctttcgatc
    80041 cctgaaacaa cctccgaacc aaatcggtta gatatcccgt ttatcaacag tccaatagag
    80101 aaacttcgat tattcttcaa tcctttagca atgatgtttt ctttatagtc caacgctgaa
    80161 atcgcttctg atattttttc catattcttt tccttcagct gctgaccgtt taaatagcgg
    80221 gaaactgttc ccactgaaac accagccatc ttagccacgt cacggatcga tgccatacat
    80281 tttcactcct gccagttaca tttgatttct ttttcttgtt gttcgaccat gatgaccgct
    80341 ttctttgcat aatgccgctt gtcatcaata tccatataac taaagtcttc agaagtgagt
    80401 tcaaaaacaa gcagtctttc ctcttgagac cgcaattcat ctttacgaaa agctttcaat
    80461 aatttcgttc tttggatgac aacgccgtca attaatcgga catagacaag agtacttgtt
    80521 ttacctgaaa cacttcctgt atttttaact ttaattgata ttattacttt gtcaatatcc
    80581 gttttgactt ccatctgact gtattcaaat gttgtatagc ttagaccatg tccaaaagga
    80641 taaaatggac ttccgcttaa atcataataa ttctcttgtt tagaagcagc acgctgatag
    80701 taataaacag gtagttgccg actatttcta ggataagaca aactcaatcg tccgcttggg
    80761 ttatttcttc cagaaatcat ctgcgcaatg gcttttccac cctcctgtcc aggaaaccat
    80821 gctgttgcaa tggcattcgt aaatgactcg attttcatca aatcgtaggg tcttccttgc
    80881 acaagtatcg tgatgattgg cttgcctagt tgatacaatt gttcaatcag ctgttcttgg
    80941 tatccaccta aagaaagaga agcaacatct acattttctc cagaatccat gttgatccct
    81001 ttcgatgaaa ctgccccgtt acgaagaaat tccatatcaa agttccgcgc acttgatcca
    81061 cctagaactg caatgatcac atctgagttt tgagcaaggg tcaccgcttc taataatttt
    81121 tcttcctgat cctcctgatt tcttacttca catccttgtg cataagaaac ctttgattgg
    81181 ggaaactctg tttttatctc ttgtactatc ttttttttca aacggtcttc tgtttgtggt
    81241 gcagagtagt ctcccaacaa gtggtaaaca tcgtgagcat ttggacctat aacagcaatg
    81301 ttttttactt gttgatccaa cggcaatata ccgtcatttt ttagtaaagt gatactttct
    81361 tttgctgtct ctaaatttaa gtgctctgat tcctccatga gatgatccca atactccttt
    81421 ggatcgtttg caaatggctg ttcaaataaa cctaataaaa atttgacaga taaaactcgg
    81481 cgaactgctt gatctagtag cttttcatct acgacttgat tatcaatggc ttctgcaatc
    81541 ttggtatagg tctcatccca caaactgaga tcgattcctg ccgctaatgc atatgctgca
    81601 gcagtctttt tatctgtaaa aacatcggat aaacgatcca aagccacacc gtctgccata
    81661 acgattcctt gataaccgat ctcttttctt aatgtttgct caaaaagcgc tcgattgata
    81721 tgacaaggta tcccgtcgat gtcattataa gcagccatga cacctactgc atttcttgta
    81781 ctcttcaata atggtccgta aatatcggag aactctctgc gtccaatcgt tactgtgcct
    81841 gaattatgac cgcctaaagc ttctccttgt gcgatacagt gctttaacac aacaccgatc
    81901 tgatccttct tcttattgat ttcctctact gtctgatcaa gaaaagaaac tttttctgaa
    81961 ataatctctc cttggaaccc tcgaacgacc gcttcagaaa aacgagctga gagaatcgga
    82021 tcttccccaa agcactcttc tgtccttccc caacgaagga tcttttgcca gatccaaagt
    82081 cgacaccagc gctaaatgaa cacctttagc agccagttct tttgccatca atcgactcga
    82141 ttgttctaat aatgctacat tgaaagtatt tccacggccg atattcgttg gataagaaat
    82201 cccatccaag ccttgatgac catgtggaca ttcttctaca agcaaaactg gaattttcca
    82261 tcgcgaatgc tgtagtacat attcttggac taggttagcc accttccagc tttcttttgc
    82321 aggaatccca ttcttataat ctgttttaga ccacggatca gagcgaaaca gaccgtataa
    82381 ggcacccaga ccgcctcccc atttaacatg ttcttttaac ttttctgtta attcgatctt
    82441 gtctccgttt ttttcataac attcccaacc atacaaatgc tggtttacct gtcctacttt
    82501 ttcagcaata ttcatcctcg aaagtaaatc ttctactctt tggcggatgg ttaactttgg
    82561 gttttgatac gggtaatcgt acaccttaat atcctccttc tgccaatttt gccttattag
    82621 cggctaatac aaatggcagg aataaaaata catctagaat gataagtatt actgttaaga
    82681 ctgctgctcg tatatcgcct cctgtagcaa taaaagattg tataaccggt ggagtgatcc
    82741 aaggtgcagc agcaactgtt ttactgatga ttccaagact tgtggctgcg taggcaataa
    82801 ccaagttaat agatggtata atagcgcatg gaatcatata tattggattc atgactactg
    82861 gtaatccaaa cataattggt tccgtaatat taaataaaca agtagtcaga ccaaatttag
    82921 cgattgatcg ctgttcttga cgtttagaag cccacaagat agcaataact aacggtaaaa
    82981 tacacccgcc acctccgatc aatccaaatg cattggtaaa gggctccgta ataatattag
    83041 gaatttcttt tcctactgaa aaagcatcca tgttttcctg aatagactgt aacaaaggtg
    83101 cttgccgtat aggagccaaa atactcgaac catgcatacc aaacacccat aagaaatcag
    83161 agaaaaactg taaaaataag atgcctggga cggataaaac aaaagctttc aatggtgtct
    83221 gaatcgctaa ttcaattaat tgcggaacat tcaaaccagt cgtatggttt aaagtaaaaa
    83281 cgacaactga aaaaaataaa atgacaacta tttctggtac taaagaatta aatgacgcag
    83341 ctactgccgg tggaactcct tctggcatcc tgattttaaa actcttcatt ttcgctaatt
    83401 tgataaataa ttctgtactg acaagggcag caatcatcgc cgttgctaag ccagacgaag
    83461 aagtcagact ttgtaagaaa acccctgtag cttctgctgt atttccgtcc atcaaagtga
    83521 ctgtacttga taaagacatc aaaataaaca ttacggctgt acttagaatt cctgcatgaa
    83581 caggactaaa tgatggatca tcaatcacgc ctgtttggat atagtgggtt gccaaattcc
    83641 agccgatatt gtaacacacg ataatagcta aaatactcat cgtaccatta ttcacgattg
    83701 aagcaagttc agccaatgga cttagatcaa gtattctttg gactgttgca tttgaaaaaa
    83761 tcagagcatt cagcaaaacc atgacagaag cagccattac taacggcata gtaacgataa
    83821 aactgtctcg aatggccagc aagtgtcgct ggctactcat cttagatacg attggtagca
    83881 ttttttcaga tagtctgtct acgactttca ttatttcatc tcctagattc taaaattgaa
    83941 ccggttcatt tttaatatag cacttttttt aaagattgca acacattttt ttaaaacgct
    84001 ttctaaaggt ggtggatttt ttatgacttt tgaaaaatta ttctatttaa tggtattttg
    84061 tgaatttttt ctcttccatc cgtttgaagt tttactttcc aatggtataa tttctttatc
    84121 ctatcaaatg ggggaagtat tttgaagaaa ttaatcgtac tatttatttt gtctgcggga
    84181 cttttgacat tgactggctg tgatttgttt ggcggctctg accaatcctc ggacgaaaca
    84241 accgattctt ctgtcttaaa agcggaaaaa gcagatatca ccaacagtgt atatacgcta
    84301 aaagtacgta aagatatgga tttatccgcg ggacagttga catttacaga taaaaaaatg
    84361 gaatggacac gcacgtatca gacacaagga gctgattctt ctgaatcatc tgaagaaaaa
    84421 acagtgctga cagatatcaa gattactacc aaagatgacg aatatattat ttcaggaaaa
    84481 gaaaataaaa aagaagcaac agtcacattt accaaaatcg gtaattaccg tttgaaggat
    84541 aaggatggca acatctacag tctatagtgc catctgttgg atcttctttt gtttctcccc
    84601 ttcttttctg ctatagtaaa gaagcaagat gactgtaaag gagacgaaat ggatgatcga
    84661 tagtcctgat tattgtacat gtaataacaa caaaaatatc catacagaat ttaatgatca
    84721 aggaagtttg agtatatgcg acaattgcca caaactagtc aaagattctt ttaaatcgtt
    84781 tgaatcttat cctgtcaaaa attatgtaaa aagcaaaaga agataagcaa aatcaagcaa
    84841 aactcactat ggctgatttt tatgaacttc aaactcagct tcttcctttg atcaagcttc
    84901 aaaaactgga atcagtaaaa caaacagtgg atcatttcag ttcacaaatc aaagagtaac
    84961 gttttattta tttcacatct ttgaatataa aataaccaaa cgatagaaag acttattcta
    85021 catcacgtag taatttttct ttcccgtcgt ttggtttttt acttttagcc taattcttga
    85081 cctttcgcat gctgattatc tgtaaaatat tttccagcag gctttccttc caattcagct
    85141 aatttttctt ggatctgacg aatcaccttt tttgcatctt ctggattttc tacaaaatcg
    85201 aatgtatccc catccacttg tattttagga catacatcaa aatcctcata ccattgatta
    85261 tagcgggtgt tcagtgtttc gtaataggtg tataacgttt catcgctttc tagctgttca
    85321 tagtcacgcc cgcgtttttt gatacgttct agcatcgtgt ccaaagaaac tttgatatgg
    85381 accatcaaat caggacgttt ttttggagca acatcatcta actcgtttag catcgtatct
    85441 aataagctat cgtactgctg tacttcgata tccgttaccc gacctaaatc agcatttaga
    85501 tggaacaaca gactatcttc gtagatggag cggtctagca cattgtcatc gttcactaaa
    85561 gcatttttca ttgctaaaaa tcgcttattc aaaaagaaga tttgcaataa aaatgcgtac
    85621 tgctcaggat ttgaataaaa aagcggcaat acttcgttat cttcgacatt ttcataaaat
    85681 ggtttagaat caatctcttt tgcaagcata tccgtcaaac tgctcttacc tgcaccaatc
    85741 gttcctgaaa tcaaaatcac tgacatacaa cccttcctct tctataagta ctcgcctacg
    85801 taagtttcaa caggcaattt ttcaaaatca tattcacgta cagcttggtc tgattttaaa
    85861 tacgtgtgaa gactttgtgt aatcatcaag ttcgtaggta ccgtctcttc ttgtacgatg
    85921 atcatcggtt ttttcaacat agttgccaca cctaattcgt aagccgttcc tggatcgatt
    85981 gtttgatgct caaagtcaag gatagccaaa acaaattctg catttgtcaa ctcttccata
    86041 tctttttcgt atacttcctg cgcccatcca gcgctgaata gttcataatt gctttcttgg
    86101 tgatgacgtg gagagtagaa acttgtgact gttttgtttt cctccaacgc tttttcgata
    86161 cgacttactc gatcgatttg ctcctctgaa aaaaatggtc ctgctaaata tatttgactc
    86221 attattttgc ctccttcaat aataactgat ttttaataga tactgctcgt aattcattga
    86281 ccagttccaa tggattgttg gaaaagatca cttgatccaa ccatttttta tccataaaat
    86341 cctcttttgc aaaagtttct aataattgtt gcaagccgct gtaataaccg ccaatattca
    86401 atattccgat tggcttatca ggtgtcaggc cgatcgctat ccaagaaaga agttgcgaaa
    86461 attcctccaa tgtacctaga cctccaggga aaacgaggac agcatctcct ttttcaaata
    86521 ataatacctt tctttcatca attgtctctg taggaataaa tgtagtaaca tctttcccag
    86581 gcagctcagt ttcaaaaagg ccatttggat agatacctgt gacttttccg ttattttcca
    86641 gtactgtttt actaatcact cccataatcc cggagtatga accaccgtaa accagttcga
    86701 tttcttcttg tgccatatat tttcctaacg tttgcgcaat aaatttgtaa ctttctttat
    86761 tgccaaaacg ggaaccgcaa aaaacagtaa gtttcataaa aaaacactcc ctaactcaaa
    86821 agtctatctt cattctacac gtgttttttt aaaataaaag actagatttt gtagtttttt
    86881 agtggtatat agatcaaaca ccactatata tagtatttgc aaaaaaataa tttttcagct
    86941 attttacagt aaccaaaaaa ataaataact agtaaatata aaattgaaac gacttactta
    87001 tagaagaaat tgggatttcg tcctgcatgt caataacacg cattatttaa atagtcacac
    87061 acttgtttct cctattaatg aaaaatccat tttattctcg tgttatgttt caccaacgcc
    87121 tgatgtttct ctaaataaaa aagccgacga accaaataat cgaaatttga tcattttggt
    87181 tcatcagctt gttcccaaac ctttgtatta acgataaata gctggattcg taaaactatc
    87241 acttggatca tcactgctgg aagaaaattc ggtgataacc gcgcctgttg cacctgcctg
    87301 gaaccagtgt ttaatatttt gttcgatcgt gtactgatct ccagcgtgaa gtatgatttc
    87361 tttttttgcc gtatagtaac gttcttgccc ctttggaata atacaggaaa gtttttttgt
    87421 ttcttttcct tcgacataaa gatatactaa gccttttcga caacgaaagg tttccttttt
    87481 tccttcattc tcatctcgag gtgggtgccg atgctctgga caagtttgat aaggcaataa
    87541 taccagttct ttcccacagt atcgctcatt attttcataa acaaataaat tcaatccttc
    87601 agtctcgatt gctcctaatc caaaatctgt atattcgatt ctttctaatt ctgtttcttt
    87661 caatactact cctgaatcta ggaacatttg ttgtactctt ttcttgtaat ccattctgtt
    87721 cctcctaact gattgtcaag tcatcccaag atatctcttc ttcctctttt tcttcttgga
    87781 tgacttctgc atttgggtca actggttttt tcaataataa aatagttatt cccgtagcaa
    87841 aagaaccagc taacaatgca ccaatgaatg cccatggtct ggtcatcgta gcgactgcaa
    87901 acattcccga tgccggaata cggctatctg cgccccaaaa catgctcaat ccaccgccga
    87961 ctgccccacc gactcccgtt gctatgacat tgcgtgccaa gtcgttcaat acgataggga
    88021 aacatccctc tgtgatctga cagatcccca taggaaaagc ggtcttcaat gtatcgattt
    88081 cttgacgatt gaatatattt ttacgaatga ttttccctaa gaaataagcg atcgtcaagc
    88141 cgaatggggt taccatcgaa gctaaaatca atacagtgat tggttcatag attccttctg
    88201 aaaatcgtgc cacaccccct tatccagaat aaatggtaat ccagaaacag ccgggtatct
    88261 gcggtaataa gcctaaccaa acgaaaaata tgagaagcta atatgagaag ctatttttgt
    88321 ttggctgttc ttattacttg atgcagggca gctttttcac aacctctttt tttatttatg
    88381 tttcataatc aatatggtaa ggatgcagct ccgtatggta gaccgcctcc gaatattcaa
    88441 tcatttcccc aatttgcgta gacgatttcc gtatccgttt gatgccgatc tgtgcgtctg
    88501 ttttcagaat ttcttgttct tcttctgtta aaaatactgc cgagaaatca tcagaaaatg
    88561 agtcaatagt atatcctttt ttcgtcagca aacgatacaa agattctttg ccaaattctt
    88621 ctctgctgaa ttgcatcatt tcttgtggaa gataatgaac aaaataaata taaggctgat
    88681 tgttcaaata atataagcgc ttaaaacaaa cagcttgctc accgaaaaag gaaaacaaag
    88741 gatcttcctt ctttatatgg accaattgca aatccagcgt ttctttccgg acttcatatc
    88801 gggagttctc caagatttgc gtaaagcttg ccgctttgga taatcgattg taaggacgat
    88861 tgcttagaac cgtcgtccca cgaccacttt tctttgcgac atattcatct gatgccagca
    88921 gttcgattgc ctttcggaca gtgattttgc tgacttgaaa cagttcttct aattcacttt
    88981 ctgtcggtaa catcgaaccg actggatatt ttcctgagaa aatatcttct ttaattttat
    89041 ctgcgacttc caagtatagt acacgtgtcc ttttcataac gtcacccttt gctttactat
    89101 tactaaaaga atagcacata aaaaataaaa aaagaacaca aatcacatgt gagaagtgtg
    89161 ttctttttca ttcagctgct ttaattacaa gtttacgcca tttgaggcaa ttacttcttt
    89221 ataccaatca aaagattttt tctttgatcg attcagtgtc ccatttcctt catcgtctag
    89281 atccacatag ataaagccgt aacgtttact catttctcct gttgatgcac tgacaagatc
    89341 catacatccc caaggcgtat agcccatcaa atctacaccg tctgctactg cattagccat
    89401 cgcttcgata tgacgacgta aataatcgat ccgataatca tcaataatcg tgccatcctc
    89461 ttccatatga tcaatggctc caagaccgtt ttcaacaatg aataatggtt tctggtaacg
    89521 attgtataat tcattcaatg cgattctcag cccttctgga tcgatctgcc agccccattc
    89581 acttgcctca agaaacggat tttttactcc tcccagcaag ttcccttctg aagttgctgc
    89641 ttgtggatca gtctcattga ttgccgtaga catataataa ctaaatccga tgtagtccac
    89701 tggatattct tttagcaact ggaagtcttt ttccgtttgc tctaattttt ccggatcgac
    89761 tccatatttt ttatgggtac gcgctgtgta tgcagggtat tctccacgta cttggacatc
    89821 cgtgcagaaa aaattgaatt cttggttttg gatcattgtt gctgcctgat tgactggatt
    89881 ggcatcgatg ctgtaagttg ttgcatagat aatcatgcag ccgatttgga tatccgaacg
    89941 caattcgtgg ccgattttta cggctttgct acttgcaacg aattgattat gccatgcttg
    90001 gaaaatattt tggtactctc ctgctccatt gctttttact aatccttgac ttaaagctgg
    90061 aaagtgaaag gccgaattga tttcattgaa agtcatccaa tatttgactt tactgctgta
    90121 tctctctaat actgtctgag caaatcgttc atagaagtcg atcagttttc gatttttcca
    90181 gccaccgtat tcttttgcca aatgaagagg catttcgtaa tgagaaatcg tgatcacagg
    90241 ttcaatatca tattttaagc actcatcaat cagctgatca taaaattcta atcccgcttc
    90301 gttaggagta ccttcgtctc catttggaaa aattcgtgtc caggcaatcg aaaaacgata
    90361 acatttgaat cccatttccg caaacaaggc aagatcttct ttgaaacgat cgtaatgatc
    90421 aattcctcga tgattcgggt aaatatattt ttcttgatca atcgtccagt caaattcttc
    90481 actgccgata atcgcaaagc gctgcttacc tccaggcata gcatctgcaa cggatagccc
    90541 ttttccgtct cgatcataag ccccttctaa ttgattggca gcagttgctc caccccataa
    90601 aaatttttct gaaaaacgtg attgcatcct gatttcctcc ttattttaca attgccagaa
    90661 catcttcgtt tgcaataatc tctttttggt ctaattcaag tatatcggca aatgcatcag
    90721 tattcgtaat gacaactgga gtgattacgc tatagccagc tgctctaatt gcttcgatgt
    90781 caaaacgaat caataaatct cctgctttga cgagatcccc ttgtttgact aagatctcaa
    90841 agccattccc atttaattct actgtatcca tcccgatatg aatcaaaatc tccgctccgt
    90901 cagtcgttgt gatccctaca gcatgtccag ttggaaaaat agtcgtgatc tctccgtctg
    90961 caggtgcaac tagttctcct acttctggat caatagcgat accttttccc atcacgccag
    91021 aagaaaaaac ttggtctggt acttcactca atggcagtac tttacccgtt aaaggacttt
    91081 ttaaggtatg ccgtgctgaa gtaatcggtt ctcctgcatt cgcatgtttg ttttctaatt
    91141 gattgtcttg tgtttgttcg tcaaatccta aaatcaatgt acctacgaat gcaagaacaa
    91201 aagcaattcc tgtagctatt actgctactg tcacatttga ctctacacca tccaccgtat
    91261 taatgaaagt cggaatcgtc aataagctga ccaaactgct ggagaaagct tttactccgg
    91321 aaaatccgat aatagctcca ccaatacctc cagaaataca agcggcaatg aatggtttct
    91381 tcaaaggtaa tgtcacacca tacacagttg gttcagtgat tccaaataac gaagtcactg
    91441 tagaagaaat ccctaatgct cgaagtttcg tatcttttgt tcgcaatgct acagctaaag
    91501 cagccccacc ttgtgccaag atggctggaa gaagcattgg catcaataca tcaaacccat
    91561 attgttcgat attcaaaaac atgatcggta cgaatcccca atgcatgccg aacatcacga
    91621 atacttgcca taaacttccc atgattagac ctgctacgat tggactaaat ccataaatcg
    91681 agttgaagag accgcctaaa gcattaccgg caaccgtccc gattggtcct aaagcaagaa
    91741 atgttaatgg aaccatcact actaaaacga caagcggaac taaaatcatt tgcagaaatt
    91801 gcggaatcac tttttttacg aatggctcta atttactttg aacccatacg gctagaatga
    91861 ttggtatgac agaagaagta taaccagatg gtgaaagaat cactgggatc ccaaagaaac
    91921 tgatagcttc tcccgcacca gcaactgctg tgatagctgg atacacaagt gccatagcaa
    91981 ttgctactgc taaaaactgg ttggctttga actttttagc tgctgtaaaa gcaagcatga
    92041 caggtaagaa ggtaaagaca ccatctgctg cagcaaacaa tatttgataa gtaccgctat
    92101 cagctgtcag ccagcccatc accgttgcca atgataagaa tcctttcaat accccggcgg
    92161 ctgccatcgc ccctagaaaa ggtgtaaata tactagagat aatatcgatc agacgattca
    92221 aaatattttt ggactcttct tttccatcct ccgaaactgc aagaccttcc tcatccacga
    92281 tcgattgata aacatctgct acattactgc caatcactac ttgatactga ccgccacttt
    92341 gtacgacttg gatcacgtcc gggtcttctt ttaacttttg cgtatctgct aaagattcat
    92401 cttttaatct gaatcgcaac cgcgtagcac aatgtactaa acttttgaca ttcttttgtc
    92461 ctcctaccgc ttcccataca cgacgaccaa ctgcttgatt atccattgtt ttttccttct
    92521 ttctttttta
//
LOCUS       DAZULR010000003        88527 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.003, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000003 DAZULR010000000
VERSION     DAZULR010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 88527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 88527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..88527
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.003"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            101..544
                     /locus_tag="ACG8ZV_000184"
     CDS             101..544
                     /locus_tag="ACG8ZV_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFS4995556.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(550..1734)
                     /locus_tag="ACG8ZV_000185"
     CDS             complement(550..1734)
                     /locus_tag="ACG8ZV_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HFS4995557.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            2002..2700
                     /locus_tag="ACG8ZV_000186"
     CDS             2002..2700
                     /locus_tag="ACG8ZV_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HFS4995558.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2707..3384
                     /gene="nth"
                     /locus_tag="ACG8ZV_000187"
     CDS             2707..3384
                     /gene="nth"
                     /locus_tag="ACG8ZV_000187"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HFS4995559.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(3510..4043)
                     /locus_tag="ACG8ZV_000188"
     CDS             complement(3510..4043)
                     /locus_tag="ACG8ZV_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995560.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(4340..6721)
                     /locus_tag="ACG8ZV_000189"
     CDS             complement(4340..6721)
                     /locus_tag="ACG8ZV_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HFS4995561.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(6711..7358)
                     /gene="recU"
                     /locus_tag="ACG8ZV_000190"
     CDS             complement(6711..7358)
                     /gene="recU"
                     /locus_tag="ACG8ZV_000190"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HFS4995562.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            7422..7961
                     /locus_tag="ACG8ZV_000191"
     CDS             7422..7961
                     /locus_tag="ACG8ZV_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HFS4995563.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            8051..8470
                     /gene="gpsB"
                     /locus_tag="ACG8ZV_000192"
     CDS             8051..8470
                     /gene="gpsB"
                     /locus_tag="ACG8ZV_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HFS4995564.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            8492..8859
                     /gene="rnpB"
                     /locus_tag="ACG8ZV_000193"
     ncRNA           8492..8859
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACG8ZV_000193"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            9068..10234
                     /locus_tag="ACG8ZV_000194"
     CDS             9068..10234
                     /locus_tag="ACG8ZV_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HFS4995565.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            10280..11776
                     /locus_tag="ACG8ZV_000195"
     CDS             10280..11776
                     /locus_tag="ACG8ZV_000195"
                     /EC_number="3.4.17.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HFS4995566.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            11857..12540
                     /locus_tag="ACG8ZV_000196"
     CDS             11857..12540
                     /locus_tag="ACG8ZV_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFS4995567.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            13185..14375
                     /locus_tag="ACG8ZV_000197"
     CDS             13185..14375
                     /locus_tag="ACG8ZV_000197"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008890 - glycine C-acetyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HFS4995568.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            14477..15430
                     /locus_tag="ACG8ZV_000198"
     CDS             14477..15430
                     /locus_tag="ACG8ZV_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HFS4995569.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            15499..16848
                     /locus_tag="ACG8ZV_000199"
     CDS             15499..16848
                     /locus_tag="ACG8ZV_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFS4995570.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVIAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(17031..17354)
                     /locus_tag="ACG8ZV_000200"
     CDS             complement(17031..17354)
                     /locus_tag="ACG8ZV_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995571.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            17483..18646
                     /locus_tag="ACG8ZV_000201"
     CDS             17483..18646
                     /locus_tag="ACG8ZV_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFS4995572.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            18716..20065
                     /locus_tag="ACG8ZV_000202"
     CDS             18716..20065
                     /locus_tag="ACG8ZV_000202"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFS4995573.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(20110..20541)
                     /locus_tag="ACG8ZV_000203"
     CDS             complement(20110..20541)
                     /locus_tag="ACG8ZV_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4995574.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            20929..23571
                     /gene="alaS"
                     /locus_tag="ACG8ZV_000204"
     CDS             20929..23571
                     /gene="alaS"
                     /locus_tag="ACG8ZV_000204"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HFS4995575.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            23771..24367
                     /locus_tag="ACG8ZV_000205"
     CDS             23771..24367
                     /locus_tag="ACG8ZV_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFS4995576.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            24489..25637
                     /locus_tag="ACG8ZV_000206"
     CDS             24489..25637
                     /locus_tag="ACG8ZV_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFS4995577.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(25675..26088)
                     /locus_tag="ACG8ZV_000207"
     CDS             complement(25675..26088)
                     /locus_tag="ACG8ZV_000207"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HFS4995578.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            26167..26598
                     /locus_tag="ACG8ZV_000208"
     CDS             26167..26598
                     /locus_tag="ACG8ZV_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HFS4995579.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            complement(26697..26930)
                     /locus_tag="ACG8ZV_000209"
     CDS             complement(26697..26930)
                     /locus_tag="ACG8ZV_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFS4995580.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            27113..28783
                     /locus_tag="ACG8ZV_000210"
     CDS             27113..28783
                     /locus_tag="ACG8ZV_000210"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HFS4995581.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            28930..29316
                     /locus_tag="ACG8ZV_000211"
     CDS             28930..29316
                     /locus_tag="ACG8ZV_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995582.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            29303..30001
                     /locus_tag="ACG8ZV_000212"
     CDS             29303..30001
                     /locus_tag="ACG8ZV_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HFS4995583.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            30006..30470
                     /gene="lspA"
                     /locus_tag="ACG8ZV_000213"
     CDS             30006..30470
                     /gene="lspA"
                     /locus_tag="ACG8ZV_000213"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HFS4995584.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            30467..31378
                     /locus_tag="ACG8ZV_000214"
     CDS             30467..31378
                     /locus_tag="ACG8ZV_000214"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFS4995585.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            31613..32152
                     /gene="pyrR"
                     /locus_tag="ACG8ZV_000215"
     CDS             31613..32152
                     /gene="pyrR"
                     /locus_tag="ACG8ZV_000215"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HFS4995586.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            32166..33449
                     /locus_tag="ACG8ZV_000216"
     CDS             32166..33449
                     /locus_tag="ACG8ZV_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HFS4995587.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            33462..34388
                     /locus_tag="ACG8ZV_000217"
     CDS             33462..34388
                     /locus_tag="ACG8ZV_000217"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HFS4995588.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            34407..35687
                     /locus_tag="ACG8ZV_000218"
     CDS             34407..35687
                     /locus_tag="ACG8ZV_000218"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HFS4995589.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            35692..36768
                     /locus_tag="ACG8ZV_000219"
     CDS             35692..36768
                     /locus_tag="ACG8ZV_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="HFS4995590.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            36773..39958
                     /gene="carB"
                     /locus_tag="ACG8ZV_000220"
     CDS             36773..39958
                     /gene="carB"
                     /locus_tag="ACG8ZV_000220"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HFS4995591.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            40012..40788
                     /locus_tag="ACG8ZV_000221"
     CDS             40012..40788
                     /locus_tag="ACG8ZV_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HFS4995592.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            40785..41717
                     /locus_tag="ACG8ZV_000222"
     CDS             40785..41717
                     /locus_tag="ACG8ZV_000222"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HFS4995593.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            41714..42430
                     /gene="pyrF"
                     /locus_tag="ACG8ZV_000223"
     CDS             41714..42430
                     /gene="pyrF"
                     /locus_tag="ACG8ZV_000223"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HFS4995594.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            42437..43066
                     /gene="pyrE"
                     /locus_tag="ACG8ZV_000224"
     CDS             42437..43066
                     /gene="pyrE"
                     /locus_tag="ACG8ZV_000224"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HFS4995595.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            43054..43368
                     /locus_tag="ACG8ZV_000225"
     CDS             43054..43368
                     /locus_tag="ACG8ZV_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995596.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            43406..44047
                     /locus_tag="ACG8ZV_000226"
     CDS             43406..44047
                     /locus_tag="ACG8ZV_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbR-like 5'-deoxynucleotidase"
                     /protein_id="HFS4995597.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            44090..44782
                     /locus_tag="ACG8ZV_000227"
     CDS             44090..44782
                     /locus_tag="ACG8ZV_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HFS4995598.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            44779..45681
                     /locus_tag="ACG8ZV_000228"
     CDS             44779..45681
                     /locus_tag="ACG8ZV_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFS4995599.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(45839..47545)
                     /gene="efbA"
                     /locus_tag="ACG8ZV_000229"
     CDS             complement(45839..47545)
                     /gene="efbA"
                     /locus_tag="ACG8ZV_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HFS4995600.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            47735..48358
                     /locus_tag="ACG8ZV_000230"
     CDS             47735..48358
                     /locus_tag="ACG8ZV_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995601.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            48808..49857
                     /gene="trpX"
                     /locus_tag="ACG8ZV_000231"
     CDS             48808..49857
                     /gene="trpX"
                     /locus_tag="ACG8ZV_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan ABC transporter substrate-binding
                     protein"
                     /protein_id="HFS4995602.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            49854..50735
                     /locus_tag="ACG8ZV_000232"
     CDS             49854..50735
                     /locus_tag="ACG8ZV_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4995603.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            50738..51508
                     /locus_tag="ACG8ZV_000233"
     CDS             50738..51508
                     /locus_tag="ACG8ZV_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4995604.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            51787..52641
                     /gene="aroE"
                     /locus_tag="ACG8ZV_000234"
     CDS             51787..52641
                     /gene="aroE"
                     /locus_tag="ACG8ZV_000234"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0019632 - shikimate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HFS4995605.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            52819..53982
                     /locus_tag="ACG8ZV_000235"
     CDS             52819..53982
                     /locus_tag="ACG8ZV_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFS4995606.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGGQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            54099..54509
                     /locus_tag="ACG8ZV_000236"
     CDS             54099..54509
                     /locus_tag="ACG8ZV_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFS4995607.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            54683..56911
                     /gene="topB"
                     /locus_tag="ACG8ZV_000237"
     CDS             54683..56911
                     /gene="topB"
                     /locus_tag="ACG8ZV_000237"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFS4995608.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            57082..57366
                     /locus_tag="ACG8ZV_000238"
     CDS             57082..57366
                     /locus_tag="ACG8ZV_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995609.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            57526..57762
                     /locus_tag="ACG8ZV_000239"
     CDS             57526..57762
                     /locus_tag="ACG8ZV_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFS4995610.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            57759..58158
                     /locus_tag="ACG8ZV_000240"
                     /pseudo
     CDS             57759..58158
                     /locus_tag="ACG8ZV_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
     gene            complement(58825..59769)
                     /locus_tag="ACG8ZV_000241"
     CDS             complement(58825..59769)
                     /locus_tag="ACG8ZV_000241"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HFS4995611.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(60065..61009)
                     /locus_tag="ACG8ZV_000242"
     CDS             complement(60065..61009)
                     /locus_tag="ACG8ZV_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFS4995612.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            61230..62444
                     /locus_tag="ACG8ZV_000243"
     CDS             61230..62444
                     /locus_tag="ACG8ZV_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4995613.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            62466..64481
                     /locus_tag="ACG8ZV_000244"
     CDS             62466..64481
                     /locus_tag="ACG8ZV_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HFS4995614.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(64564..65937)
                     /locus_tag="ACG8ZV_000245"
     CDS             complement(64564..65937)
                     /locus_tag="ACG8ZV_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFS4995615.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(65963..66247)
                     /locus_tag="ACG8ZV_000246"
     CDS             complement(65963..66247)
                     /locus_tag="ACG8ZV_000246"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFS4995616.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(66249..68264)
                     /locus_tag="ACG8ZV_000247"
     CDS             complement(66249..68264)
                     /locus_tag="ACG8ZV_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFS4995617.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPVLDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(68443..68748)
                     /locus_tag="ACG8ZV_000248"
     CDS             complement(68443..68748)
                     /locus_tag="ACG8ZV_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HFS4995618.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(68837..69868)
                     /locus_tag="ACG8ZV_000249"
     CDS             complement(68837..69868)
                     /locus_tag="ACG8ZV_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFS4995619.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            70075..70950
                     /locus_tag="ACG8ZV_000250"
     CDS             70075..70950
                     /locus_tag="ACG8ZV_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFS4995620.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(71102..71944)
                     /locus_tag="ACG8ZV_000251"
     CDS             complement(71102..71944)
                     /locus_tag="ACG8ZV_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFS4995621.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(72036..73913)
                     /locus_tag="ACG8ZV_000252"
     CDS             complement(72036..73913)
                     /locus_tag="ACG8ZV_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFS4995622.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(73910..75331)
                     /locus_tag="ACG8ZV_000253"
     CDS             complement(73910..75331)
                     /locus_tag="ACG8ZV_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFS4995623.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(75334..78723)
                     /locus_tag="ACG8ZV_000254"
     CDS             complement(75334..78723)
                     /locus_tag="ACG8ZV_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFS4995624.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            78980..80371
                     /locus_tag="ACG8ZV_000255"
     CDS             78980..80371
                     /locus_tag="ACG8ZV_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4995625.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(80444..81091)
                     /locus_tag="ACG8ZV_000256"
     CDS             complement(80444..81091)
                     /locus_tag="ACG8ZV_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFS4995626.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(81099..81785)
                     /locus_tag="ACG8ZV_000257"
     CDS             complement(81099..81785)
                     /locus_tag="ACG8ZV_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4995627.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(81791..82864)
                     /locus_tag="ACG8ZV_000258"
     CDS             complement(81791..82864)
                     /locus_tag="ACG8ZV_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4995628.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            83086..83760
                     /locus_tag="ACG8ZV_000259"
     CDS             83086..83760
                     /locus_tag="ACG8ZV_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFS4995629.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            83765..85105
                     /locus_tag="ACG8ZV_000260"
     CDS             83765..85105
                     /locus_tag="ACG8ZV_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFS4995630.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(85254..86240)
                     /locus_tag="ACG8ZV_000261"
     CDS             complement(85254..86240)
                     /locus_tag="ACG8ZV_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HFS4995631.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            86964..87995
                     /locus_tag="ACG8ZV_000262"
     CDS             86964..87995
                     /locus_tag="ACG8ZV_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4995632.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            88104..>88527
                     /locus_tag="ACG8ZV_000263"
     CDS             88104..>88527
                     /locus_tag="ACG8ZV_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HFS4995633.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQI"
BASE COUNT        28200 a        15764 c        17933 g        26630 t
ORIGIN      
        1 tttttcttgg tttcagattg ggttttccta caaaatattt ttatctttgt tgaataggaa
       61 acaaaaaaac aatataatga aagaaaaaga aggtgtagaa atggataaaa gacaactgct
      121 aatagaagaa tatctggatt tagctaatga gattattcat cgtaataaac cagaaatgga
      181 aaaagaattt gcaggattta ctctaaatga actagaagtg attgaacata tcgggaaaat
      241 ccctgatcct aacgtgacaa aattagcgaa tgctagttac atgactagag gagccatcag
      301 taagctaaca aaaaaactga tagctagagg gatcataaac acttatcaaa gcgaagagaa
      361 taaaaaagaa atctattttc aattgacgcc aatcggacaa aaaataagga atagacacga
      421 gcaactccat caaaaatggg tacagcgaga tgctactgta tttgaaaata tgtcaaaaga
      481 agaatttgac acagtatttc gttttatcgg tcgatacaga gaatttatac gaagtagcaa
      541 atgaagctac tattttttat tgtagtgata ataggcaaaa atcataagca aaaatccgaa
      601 taccgtcgga agaaatggtg ctgcagcata aagctgtcct gcgattagcg ggccgatgac
      661 gcgcgataga gattgtatac tttgggtacc gcccattaca agaccttgct ggttatctga
      721 gacagaattg gatagttggc cattgaatac aggagtaaaa atagaatcac cgaaaccata
      781 acagataatc ccaaataaaa acaaaatcgg cagtagaaga attccagata atgtgatgaa
      841 tagataggcg aggatttcac tgaacatccc tattcttgtg atctgctgtt ctgaaaattt
      901 tttgagcaat cgaggcataa tgaacaattg cgagacagta tccaagattc caatcaaaga
      961 gaagcttaaa ccaaccaacc cagccttcca ctgaaaggcg tcaatcgaaa attgagaaaa
     1021 gatagattga agagagccag ctgccaacca aacagcaaaa cctgctgtca ataaaggaat
     1081 aacggatgaa atcttgaata attgttgtaa ttggtgaaaa ggtcttacat gggagaaact
     1141 taaatctact gaacgttttt ttattggaag gctttctagc ataaatgtgt agccataaac
     1201 ggcatttaag aaagtaaaga gtgctccaat aaatatagga acagaattcc ccaactcagc
     1261 taatagaccc cctataatag gacccagcgt tgttcctata ccgactaaag cacccatcca
     1321 tccaaaaact ttggttcttt cattaggttc cgtgatgtcg gcaaagtaag catataaggt
     1381 ggagatttct cctgccgtca atccttcaat gatacgacca aggaacaaca tccatatcga
     1441 atttcctaaa ccaaaaagca aatatccgat acttgatcct aataaactga taataaggat
     1501 cggatgacgc ccaaaatgat cacttaagct accgagaatg ggggcagata agaaggcagc
     1561 tagagcataa acagacatga gcaaagtgat atagaaagct tgctgatgta tggagtgaga
     1621 ataaggcagc gttaaaaacg gaagtacagg actgacgata gtaaatccta atccagtgaa
     1681 taagacagag acgtatccaa aaactttaga atgtttattt gtgaaactgt acatgtaaaa
     1741 actcctttat gcaataatgt taacttggaa acaaaaatag tgtatagtaa ttttgtttcc
     1801 ttgtcaacat tctaaggaac agcgaaatct acttaattta tttattccga aaagtgaaga
     1861 tacgcatcaa aaacatgaac aaacaaaaat caagtagacg acattgtaaa tctgaccgat
     1921 cagtgaagta aatagaaaag aaacctgttc ttgcttccca tgtttttttt acgtatactg
     1981 tgattgagcg gaggagaaat catgttgaat ttagaaaatt acttaagcgc tggacaaaca
     2041 gtcatatcta atcttttact taaaaattat cataggatcg gtctacaatc tgaagaattt
     2101 ttatttgttc tacagttgca tatggcacag cttgaaggag atactttccc tgatttgcag
     2161 atgattgcta tggatatggg aatcaaacaa gatcagattt ttcaaatact ggatcgtctc
     2221 gtaacaaatg gatttatcaa gatagaaacg acgattgtca acggtaaaaa agcagatcga
     2281 tataatcttt accccatcta tgatctatta ggtgagtatt taaaaacaca agaaaaaaaa
     2341 tacgaagaaa aaacacaaga aaaagaaatc cagtcagtgt atcaattatt tgaacaagaa
     2401 tttggacgcc cgctttcttc gatcgagttc cagcggatcg gacaatggct agaagaagac
     2461 cattatcagc cggaaatttt gaagctagca ctgcgggaag ccgtattaaa tcaggcttat
     2521 agttttaatt acgttgaccg cattttgcta tcgtgggaaa gaaaaaatct acgtacaaaa
     2581 caacaagtgg aagaagacca aaaacgaaga aaacagcagc ttcttcaaag agaagtagaa
     2641 cagtcagctc aacaagaaga attgccgaaa gtctcactga aaaattggtt ggaggagtag
     2701 cggaatatgt taagcaaaca aaaaacaatg gaagctctag aaacgatgta tggaatgttt
     2761 cccgaagcac atggagaact caagcacaat aatccatttg agttattgat tgcagtgatc
     2821 ttaagtgccc aggcgacaga tgtatcagtg aataaagcaa cgccagattt gtttgcctct
     2881 tttccgacac ccgatgcgtt agcagaagct tcaatcgatg aaatcattct taaaataaaa
     2941 acgattggtt tgtatcgaaa taaagcaaaa aacatcaaag cgtgtgcaca gcagctgatt
     3001 gaacgtttcg atgggcaagt gccaacgtca agagaagaat tgatgtctct tcctggtgta
     3061 ggcagaaaga cagcaaatgt cgtattgggg gatgcattcg ggataccagc aatcgcagta
     3121 gatacccacg tggaacgtgt ctcaaaacgc ctgaggatct gcaaactaga tgctacggtc
     3181 atggaagtag aagaaacact gatgcggaaa gtaccacaag aattatgggt aaagacacat
     3241 catacactga ttttttttgg tagatatcat tgcacggcaa gaaatcccaa gtgcgaggta
     3301 tgtcctttgc tatcaatatg tcaagatggg aaaaatcgga tgcgtctaaa agaaaaggcg
     3361 ctaaaaaaga aaccacgcct gtagacgtgg tttctttaat tgcaaataaa tgtatgaatt
     3421 atcttgttat tatggagaaa agctgtttcg tttatctttt ttgcatgaaa aagtaaatgt
     3481 acatactcag tagctaggat ggtaacttat tacaatttat tgcgataaaa ataaaagttg
     3541 ttatttttat tgggaaaata cccgatgtag aaaataatgc cttccaatat acctataaaa
     3601 taagtccagt attccaaagg attatataaa taagtgacgt atctatctaa aggtgtaata
     3661 aaaatgataa gtgataataa aaaaatacca tttataacta aacataaact aatggatttg
     3721 ggcggtttca ggctcatcag aaaaatatag attctggtga acaacaacca taaaaaagtg
     3781 agaatcattg catgagagct tctttccata aattttcctt taagagtagt gcttaaaagt
     3841 acagaaaaaa taataaatgc aaggatagga gcaattaaag taaatttatt taataataaa
     3901 caaaattttt cagctttttt attcttggaa taacgaggta ttgttttcga taaaaaaaga
     3961 tggtgcagac aaattatgat aattaagcat actatcagat aactcaaaat gaagccttct
     4021 ttcaaaaaat tattcaaaac catatattgt attttttatt tgataataac aatgggatta
     4081 ttaagaagtg gcactaaata aaagactagt gtgtatttag ccgatttaat tataaacaag
     4141 taaatggata aagtatatgt aatgataaaa gaaaaatgga ttttctaatt tttaagctaa
     4201 atgttagatc acacatgtat atgctggata gtcttataaa aaatcatgta atacagcttg
     4261 gtacatgatt tttatttgta gctgtttttt acatagacac aaaaaagaaa ccacgcttgt
     4321 agacgtggtt tcttttttac tatctgtttc cagaagctga ggtgctgctg gatggtgtat
     4381 ggtcatttgc agcatccgct ccgctagttg ctggctcact ggaagaagca ggaggagcag
     4441 atgaagacgg tgtcgagctt tcttcggatg aagaagaagg aaccgttgtt gaagacgctg
     4501 gctcgcttgt ttctgctgtc gtgctttctt ttgaggactc agcagttgat tcgctttgac
     4561 tagtagagct agagctttga gtcgttgtct ctgttgttga gcttccagga gtctggacat
     4621 agctggaaga tggaatagtt gttgatggtg taattgcatt cgatctagct gtatattgat
     4681 ctttgtagta cagttcaccg cccacacgaa ttaatccgct tggcatctcc cagtctgtat
     4741 ttgtcacgtt agctgaaaca tactgcataa gctcgcgata aacatcagag gctacgtgtg
     4801 acgattctga agtgacaggt gtcatttttt tattgtaacc tgtccacacg gaaatcgaat
     4861 aatttggcgt atagcccgca aataggatat ctggatacac cccagaagaa ataccaagtt
     4921 ttgcatactc gtcatctgtg taattggatg ttccggtctt accggcttga tataacccag
     4981 cgatttgcgc attcgtacca gttccttcag tgatcgtatc ttttaaaatg tctgtgatca
     5041 tataagctgt ttctggagac atggctgttt ttccatctgg ctcataagtt tcttctgttc
     5101 cgtcttggaa gacgatttta ttaacatatt gaggtttgta ataagtccct ccattggcga
     5161 aagccgcata ggctgctgcc atttttaagg aagaagctcc gtattttgtc ccatcttgtt
     5221 cttccgtatt actagagatc gcattcgatt gatggatcgt actgtattcg atcccaagat
     5281 tttttaagaa agaagccact ttatctgaac cgacttcatt gaataatttg actgctggaa
     5341 cattacggga taagtaaagt gcttggcgta aagtaatggt gcccatatat tgattatccc
     5401 agtttcctac aggagtcgaa gtcccttcat agttatacgg tgcgtcagta atagtttttc
     5461 cagtagaata tttcaaatat tcaaaagctg gtccgtaatc tgtgacaggt ttcatcgtag
     5521 aaccaaaatc acgggaagta ttcactgcta agttgttgcc taaagttacg tcttctgcga
     5581 tgtgacgtcc gccaatctgg gcttttactt tcccggtatt ggtgtcgata agggtggagg
     5641 caacttgcat ctcgtcgtct gggtaagaga catactgatc cgtgttgacg atatcatata
     5701 gtttcttttg ggcgtccaga tccaaattcg tataaatctc taaaccgtct gtgtagacat
     5761 tcttatctgt tttttcttgt acttcattga tgacttcttt gacataatta tcgacgatct
     5821 tagtattgtc atcggattga gttagttctt gcagaccatc cgttaccggt acattaacag
     5881 cttgatcata ttctgtttga gagatttttt cgttttgaag catcgtatac aaaacagtat
     5941 ctcgtctttt cttcgcctga tctggataaa cataaggatc ataggcggaa ggggcttgag
     6001 gcatcccagc aagcaatgct gtttgcggta aagaaagttc tgataatttc ttaccaaagt
     6061 acatctcaga agctgtctcc atcccgtaca agccgtttga catatacact ttatttacgt
     6121 agtaggtcaa gatctcttgt ttcgattttt tttgttccaa tcttacagcc atccacgctt
     6181 cttgggcctt gcgtttcaga gtctgatcct cggcactggt ggagaagaag gaaagtttga
     6241 tcaattgctg tgtcaaagta cttccgcctt gcagtccgcc agaggtaaag ttagagaggg
     6301 cagaaccgat gatccgaata gggtcaaccc cgatgtgttt ataaaaacgg cgatcttcta
     6361 ccgacacgat cgcatcttct aatgttttcg gtaattcatt cgcagaaatt ttttcacgct
     6421 tttctgcgcc taaatcttcg aatagttcgc catcttgtgt atatagtttg gaagatacgg
     6481 tagcgtctaa ttttttatcc gtcaattcgg gcgcatcttt tgcgtaatac cagaaaagtc
     6541 ctacacctgc taaaaagagg atacagaaaa atgagagtat tcctaaaagg atcttgataa
     6601 ataatccttt tttatgtgtt ccagaggact ttccagaacc tttgccagaa ttcttcttca
     6661 cactcttttt aggagtaggc tgtttctgtc gtctagagct tctagtttgt tcatttgcca
     6721 ttcttgcttt ctccttcaat agataatgtt gataaataga agtcaaccgc gtccaaataa
     6781 ggaatccgcg gagaaatacc agttttgatc tctattccta gttcttcgat caaagataaa
     6841 ggtagtgatt tgcgtccttt ttccttttgg gcgtcccagt aagcaatcaa atgaacacta
     6901 ttcaaataaa aacagcgctt caaagacgaa aaccataaca agacaaagca gaccccattt
     6961 tgttcgaggc atgctttcat atgttcgatt tgatgggcat ggaagttttt aaagggaaaa
     7021 gatgttttgt tcttggtttc ttttgcttca aagtccaagt aaaagcctcg atagacgcca
     7081 ttatagtctg tagttgaggc ttgggtaaag taggcttcct tgatcacagc agcacttctc
     7141 ttaggatagt ctactttcac gatttggata ggggtaggct ttttatggat aaccgccaac
     7201 ccgcgggaaa gataatattt attactttca ttgattgctt cttcaaagcg catcccccga
     7261 ttgccgaatt cagtgatctg atttcttttt tcttgaattt tttcgacggg agaggcattc
     7321 ttataataag gttggccatt tggatagcgc aataccatct ttaatcacac tcctaggcca
     7381 cattatagca aaaaagcgga tagaaagaaa aggaatctga gatggataag tcaaaagtaa
     7441 tctatgtgtc tgggtatcga agtttcgaac tcggtgtttt taaagaaaat gatcctaaaa
     7501 tccaagttgt taaaaatgtt ttaaaaaaag aactccatca gttagcagaa gaagggctgg
     7561 aatgggtact tgtcagtggg aatttgggcg tcgaactatg ggctgtgcaa atagtagcgg
     7621 aattgaaaga agaatatccg gaactatctc ttggtatttt gtatcctttt tctgattttg
     7681 gtaataactg gaatgaaggg aaccaagaaa aaaaacaatt agcagaacaa ttagcagatt
     7741 atgtcgaagc tgttagccat caaccctacc aatcacctag tcagctaaag aatcacactc
     7801 gttttatact tgagcataca gtgggctgtc tgctgatcta tgatgaagaa ttccctggaa
     7861 aaacgaagta tttttttgaa gatgcacaga attaccaagc agatcatccc tacgaaattc
     7921 ggctgatcag tatggacgat cttcaaaatt ttagtgaata atcgatattg tgtttgattt
     7981 atcaactttt ttcctataca atgaaaaagg tagaaatgtt attacgtaaa tgaaaactag
     8041 aggtgtaaat atggcgaatt tggtttatag tcctaaagac attttacaac aagaattcaa
     8101 aacaaaaatg cgcggctatg atcccgttga agttgatgaa ttcttagaca atatcatcaa
     8161 agattatgaa acttacagca aagaactcct tgctttacaa gaagaaaacg atcgattgag
     8221 tgcaaaagta gctcaattat ctaaaactca aggagcagct caaacacgcg tgcaacaaac
     8281 agaggcacca aagagcgcag cagtgaccaa ttttgatatc ttaaaacgct tgtcaaatct
     8341 tgaacgtgaa gtatttggta aaaagcttga tcaacaagca agtgcagtca aaccagcaca
     8401 acctaatcca aataactaca caaatgcaga cacaagctta gatgataatg aaaaaacacg
     8461 tcaattttaa tttttgatta atgaatttgc ggttttcggg taatcgcggt ctgacttgat
     8521 caggctgagg aaagtccatg ctcgcacagg ctgtgatgcc tgtagtgttc gtgcttagcg
     8581 aaaccataag ctaaggtact ctttggagta acggcaggaa aacaagctaa ggcttcggct
     8641 atgcttaagt atccttgaaa gtgccacagt gacgaagcgg ctggggaaac ccatccggtg
     8701 gaacgcggta aacccctcga gcgagcaacc caaacaatgg taggggcgct ttttgtctgg
     8761 aagaagaaca ggacaaaaag gcagtataac tgcagataga tggttaccgc tttgtttttt
     8821 ctccctggaa aagcaaagta cagaacatgg cttatagaaa accgcaaaca tcagggaatt
     8881 aggtcgtgac aaaagtaatg cgttataaga aacaagaaaa acatttgaaa gctatttttc
     8941 aatacttcag atgaatcgtt cttattacaa aacaaacttt tgtatcaccg gttattcgga
     9001 atttgagtaa aagtgtgggg taggactgat gtcccacctc ctttttttat aaataaggag
     9061 attgtgtatg gaaaaaaaca ggaagttcaa cctcgtcgca actgcggcaa gcgggctaga
     9121 agcactggtt ggtaaagaat taagagatct tggaatcgaa tgccaagttg agaacggacg
     9181 tgcacgtttt gaaggaacaa tggaaacgat cgctacagct aatttatggt tacgtacagc
     9241 agatcgagta aaaatcgtgg ttggggaatt cgatgcgtat acgtttgatg aattgtttga
     9301 aaacgtaaaa gcattgcctt gggaagattt tcttccacta gatgcagctt ttcctgtagc
     9361 tggaaaatcg atcaagtcga aactatatag cacacctgat tgccaagcga tcacaaaaaa
     9421 agcaatcgtt gaacgtctcc gtacctatta tcaccgtcca gcttctgtac cactgacgga
     9481 aactggcgca cattttcagt tggaagtagc tttgctgaaa gaccatgtga tggtaactct
     9541 ggatacgaca ggaccaagtt tattcaaacg tggttatcgc ttagaaaaag gtggagcacc
     9601 attgaaagaa aacatggcag cagcacttat tatgttgaca aattggcgaa aagaccgtcc
     9661 attttatgat cctgtatgtg gttcaggtac gctttgtatt gaagcagcct taataggcca
     9721 taatatcgca ccaggattca atcgtgagtt tgcttgcgaa tcttgggatt ggttcagtca
     9781 agaaatcatg gaaaatgttc gatcagcagc cgaagaaaaa gcagattatg atattgaatt
     9841 agatattact ggttcagata tcaatggacg gatgattgaa attgccaaag ccaatgcaga
     9901 agaaatcgga ttaggctctt cgattacctt taagcaacaa gcagtcaaag acttcaaaac
     9961 ggataaagaa tacggggtca tcgtggctaa tccgccttac ggagaacgtc taggagaaga
    10021 agaaactgtt cggaaattat ataaagaaat gggcgatgta ttccgtccat taaaaacatg
    10081 gagtaaatat atcttgacta gcgacttagc gtttgaggaa ttttacggac aaaaagcaac
    10141 caaaaaaaga aaattgtaca atggtgcatt gcgtacggat ctattccagt attggggaac
    10201 tcgtccgcct agaaaaaaag agaaagacga ataatcttac taattgattc attcaattgg
    10261 atgtttggag gaatagggaa tgaaagaaaa agagttttta caagaagtaa aagaaatcaa
    10321 tcttctacaa caagctttag gaatcctcga ttgggataca caaacaggta tgcctgaaaa
    10381 agctagtgca taccgaagtg aagtagacag ctatctttac agcatttatt tttcaaaaaa
    10441 aatcggtcca aaaatcaaag aagccattcg ctatttttct gaacatccgg aagaattgtc
    10501 ggaagttgga actgccgttt ttgccaaagt aaaagaagag tatgatttgg aacatcgcgt
    10561 accggaagat cttatgagaa aatatacagc tgccgtttct tcagcacacg gacaatggca
    10621 aaaagctaga gaaacacaac aattttctga ttttcaacac gcattgaatc aaaatattga
    10681 attaacaaaa cagttgatac cttactggag aaaagatgaa aagacgaatt atgatgtttt
    10741 gctgaatcaa tacgaacccg ggatgactgt cgaaatcctt gataaggtat ttgatcagct
    10801 taaagaagga attctttcga tccgccgtac gctccaagaa aaagggactg aacctgaaac
    10861 agacttttta aatcggagaa tgacgaaaaa acaacagaag agatttgtag tgaaagtaat
    10921 cgaacaactt ggttatgatt ttagtcgtgg tcgtttagat gacactgtcc acccatttat
    10981 gactggaatt aatccgaatg atgcacgaat cacgacacga tggaacgaaa cagatttcaa
    11041 aatggctgtt tttggagtga tccacgaggc tggtcatggt atgtatgaac aagacatcga
    11101 tgataaatat gcgtatacac cggtttatga aggtacatca atgggtatcc atgaatcaca
    11161 atcgttgttt aacgagatca ttattggaag tagtcgcagc ttctggaaaa agcaatatcc
    11221 tttctttcaa gaatgtgcag aaggaacatt cgatgatatt ccttttgaca aattttatcg
    11281 ttcattgaac catacaaaat caagtttggt tcgtatcgag gcagacagtt tgacttaccc
    11341 tctccatatc atcattcgtt atgaaatcga aaaaatgatt ttcaatgaag gggtagatgt
    11401 tgctgaacta cctgaaatat ggaatcaaaa atatgaagag tatctgggaa tacgaccaac
    11461 aaatgatgtg gaaggcatcc tacaagacgt tcattggtca ggtgcaagct ttggttattt
    11521 tccctcttat gcattagggt acatgtatgc ggcacaatta cttcattctt tgcagcaaga
    11581 aatagatgtg gaaaatgttc tagcgtcaga cgattattct ccaatcaaaa actggatgtc
    11641 agagcatatc catcaatatg gtgcatctag aaaaccaaat caattaatca tggatgcaac
    11701 acatgaaccg cttaatccgc aatacctgat cgactatatg aaagacctgt attttaatgt
    11761 atatcaggta aaataaaata caatttacaa agatagctga aattcatcta atctatagat
    11821 gttttcagct atttacttaa gaaagaagtg gaacgaatgg ataaattaca agtgatcgct
    11881 gattatagta tggaccaatt agcgcatgat caaacaggac atgggagcga tcataccaaa
    11941 agagttgtca agttagctga aaaaattttg gagacggaac cgcaggcaga ccgctttgtg
    12001 acgcttgcag cagcttacct acatgatacg attgatgata aagtcgttaa aaatgagaac
    12061 gaggcaaagc aacagcttcg tgtattcctt cgctctttgc caatagtaga ggaacagatc
    12121 tcgatgattt tttccattat cgaaaatatg tccttttcta aaaatctctc tgaagcggcc
    12181 gaactatctc tggaaggtaa gatcgttcaa gacgctgatc gtatcgaagc attaggagca
    12241 atcggcattt tgcgtactgc ttatttcggc ggtggacatg ggcacccgat ttttgatcct
    12301 gaactgtatc cgcaaacatt caaggacaaa gaaaattacc gaaaaggcac gacagtgatc
    12361 aatcattttt atgaaaaact gttcttgctg tctgataaaa tgaatactga ttacggatat
    12421 gaagaagcca aacgaagaga aaccttcatg cgtgaattct tagaagaatt ttttctggaa
    12481 tggtctattg acgatgaaaa ttttactcca gacaattgga tcaaaaataa caaaaaatga
    12541 tggaggttgt gacagaagtg gtcagctcca agatatttcg gatcattttc cgtaaaagtt
    12601 acttctggaa cactgtttac caagaggtcg tgagcctgcc gttcagctcc gagtcacaag
    12661 gaacaatttc aaaaaatagc ttctcgtgtt tgatgaatat tgtaacttgt gattcggaat
    12721 tggcaggaga acaccgttta ttcggaagaa taggactgtg acaagacttt tgtcacagtc
    12781 cttttttcga attcaacaag taaaactttt aagaaatatt cagagagtaa aattaaaaat
    12841 tgctgataaa cgaagatgga aattttatgt atttttattg gtctatgcaa taaataaatt
    12901 aaatattcag aatacaattg attttaacga aagggcttct atcaatggtt gtgttgtatt
    12961 tatctgccca ggtagagtaa aatagatcat tatctaaaag gtaattgttc atactatata
    13021 agtcatttga aagtaaaaag atactgtaaa taaaaaatgt ggttaaataa ttctcataat
    13081 cagtgtaagc gttatcaaaa atatagcata cttgctttgt agatgaatga cacgatatat
    13141 gtttggtatg ttctgcaaga cagatgaata tggaggtgga gacaatgtct tccaaagaac
    13201 taacaatgta tttagagaaa gaattggatc aactgaaaga aaaggggtta tacaatacga
    13261 tcgacatact agaaagtgaa aatggtgctt gtatcatcgt agacggaaaa aagatgatca
    13321 atctagcatc caacaattat cttggatttg ccaatcgcga agaattgaaa aaagcatgta
    13381 ttgaagcaac cgaaacttat ggtgtaggag caggagcagt ccgaacgatc aatggttcgc
    13441 tgaaaatcca tcagcaatta gaagaaaaaa tcgcagaatt caaagggaca gaagcagcaa
    13501 tcgcctttca atctggattc aactgcaata tgggcgctat ctctgcagta atgacaaaag
    13561 aagatgctat cttatcggat gaattaaacc atgcatctat tattgacggt tgccgcttat
    13621 ccggagcaaa aatcatccga attaaacatc aagatatgaa agaccttgag aaaaaagcaa
    13681 aggaagcgat agaaagtaag aaatataaaa aaatcatgta tatcacagat ggtgttttct
    13741 ccatggatgg agacattgca cgattgccgg aaattattcc gattgttgaa aaatatggac
    13801 tgatcaccta cgtcgatgat gcgcacggct caggcgtaac tggaaaaggt gcaggaaccg
    13861 tcaagcattt tggattaagc gacaaaatcg atatgcaaat gggcacgtta tcgaaagcta
    13921 taggtgttgt tgggggttat gtagctggat cgaaaacact aatcgactgg ttgaaagcta
    13981 gaagtcggcc attcctattt tctacttcgc taactccagg tgcagctgca gctgcattgg
    14041 cttcgattac tttgatgcaa gaacatccgg aacttgtcga aaaagtttgg gaaaatgcta
    14101 attattttaa agaagaattg aaaaaagtag gctataacat cggtatgtct gaaacaccta
    14161 ttactccagt cattttggga gacgaaaaag tgactcagac tttctctaag aagctgatcg
    14221 aacatgggat ttatgctaaa ccaatcgttt atccaactgt gcctcttggg acaggcagga
    14281 tcagaaatat gccgactgcg gaacatacga gggaaatgct tgatgaagca gtagcagttt
    14341 atcaaaaaat aggaaaagaa atggaaatta tttaactaaa tttagttttt tcgtctattt
    14401 aaaattagag aacatgttca cgcatatatt gttaatcatc tgaagatagt agtaaaaaag
    14461 atcagggagg atcatcatga aaaaagtatt ggtgacagga tgtttaggac aaattggttc
    14521 agagttgatc acacggctac gtcaagaact aggcagtgaa aatgtcattg cgacagatat
    14581 acgcatgcct gaagtcattg agaaaaacga tatctttgag atcctagatg taatggatta
    14641 cgaaaaaatg cgcagcatag cagaacaata tcaagtggac acattgattc atttggctgc
    14701 tcttttgtca gctgttgcag aagcaaaacc acaattagcc tggaatttga acgtgactgg
    14761 gctggtcaat gcattggaag tcgctagaga attccagctg aaatttttta cgccaagttc
    14821 aatcggcgcg tttggtccaa atactccaaa agatcatacc ccacaagata ctcttcagcg
    14881 tcctacaacc atgtatgggg taacgaaggt agctggagaa ctactatgtg attattatta
    14941 tgtgaaatat ggcgtagata ctcgtggtgt ccgtttccct ggattgattt cttatgcaac
    15001 cttgccagga ggcggtacga cagactacgc agtcgatatt tattattcag caatcaaaga
    15061 aggaaagtac actagtttca ttgatcaagg tacatcaatg gatatgatgt atatgccaga
    15121 tgcgatcgat gccattataa aactcatgaa tgcagatcct gatcgattgg ttcatcgaaa
    15181 tgccttcaat atatcggcga tgtcttttga cccggaagag atcaaagcat ctattcaaaa
    15241 aatcatacca gattttgaaa tggattatga tgtggatcct gtacgtcagt caatagcaga
    15301 atcttggcca aattcactag atgtttcttg tgcgcaagag gaatggggct tttcgccgaa
    15361 atacgactta gatgtgatga caaaggatat gttggaaaaa ctgaaagaaa aattggtaga
    15421 gacggtataa aacaagaacc acatccaaaa agttttttat acttttggga ttggctatgg
    15481 tatgaaaggg gacaagggat ggaagaatat caagccacgc cagtaaaaga agtaaaaata
    15541 gaaaatgaat taaaacgtac gatgggattt tttactgctt tatcgactgt tatgggcaca
    15601 gtgatcggtg caggggtatt ttttaaagcc gcaagcgtag cagaagttac aggatccgcc
    15661 agtttgcata tgttttcttg gtttctcggt ggtatgattt ctgtctgtgc aggactaaca
    15721 ggagctgaac tggcagctgc tattccagaa acaggaggga tgattaaata tatcgaacgg
    15781 atttacggaa atacagcagc ttttttattg ggctgggcgc aagtcgtgat ttattttcca
    15841 gcaaatgtag cagccttgtc gatcattttc ggtacacagt tcgtcaatct atttggtctt
    15901 tcccagtcaa tgattgttcc cgtagctgtt acagctgctg tatcgatcct gttgatcaat
    15961 tttttaggtt ctaaagctgg aggggctttt cagtcgatta cgcttgtctg caagcttatt
    16021 cctttgtttg tgatcgtcat tttcggtttg ttccgacaag aaggagtaga cttccaactg
    16081 tttccgatcc aagcaggaga aaatctttca tttttctcag ccttgggagc gggcttgcta
    16141 gcaacgatgt tcgcatacga cggttggata cacgtaggaa atatttcggg agaattgaaa
    16201 aagccggcga aagatttgcc aaaagcaatt tctttaggaa tcatcggaat catgatcgtt
    16261 tatttattag taaatgcggt gttcttaaga accgcatcta tcgacggagt cgcaggaaac
    16321 agcaatgcgg caagtgacgt tgcaaaaatg atttttggcg gcttcggtgg aagactggtc
    16381 acagttggta tcttgatttc tgtttatgga accatcaatg gctataccct tactggaatg
    16441 cgtctccctt atgttattgc aaaagaaaac aacctgcctt ttagcaagct ctttgctaaa
    16501 cttcatgata aaactaaagt tcctgtagcc gcaggtatct tagagctagt catcgctatt
    16561 ggcatgatga tgatcggtgg ttttgataca ctaacggata tgctgatctt tgtcatttgg
    16621 attttttata cgatggtctt tgttggtgtc attcttcttc gtaaaaaaga acctgatttg
    16681 tttcgaccat acaaagttcc aatgtatccg tttattccac tagtagcaat cattggaggg
    16741 acttttatcg tatcaagcac gcttatcact cagacctttt tagcttcgat ggggatagta
    16801 ttgacacttg ctggtatccc gatttatctc tatttaaaac gtagatagct aaaacattcg
    16861 aattttatta gaactgcact tctctgccaa acaaaatatt ttatttaaat gaggagtacg
    16921 tggaagaaat gtcaaaagta ctcgttaatt ttgatcacgt aaatgtcgtt ttgtctacga
    16981 tgaaatagca aagtaaaaga cagaaatcgg gctcaaccga tttctgtctt ttactttgat
    17041 ttgcgtaact gaactattcg gcgtacgccg cgataaatat ttaataaaac caagcaacca
    17101 gaaatgaaaa tgggaagcca aatcagatag acagggtagc caagcacttt agacaaagca
    17161 tgtggagtca ttttatccat ttcaagaagt gcttgctgcc aagtctgaag attgaagact
    17221 agcatgaaac ccgaaataat caggagaata aatcctaaat aatgaattgt agttcttttt
    17281 cttacataag cgatcgtagc ataaaggaac agtaaaaaaa taggtacgcc aaaaacaaag
    17341 tacatattca gcatctcgac accccctttg tgtttatctt actttacttt gaaagaaatg
    17401 agaaataata gcctcgttac ttgcttgaaa cagcaaagga ctgctaagat aagagagata
    17461 caaagaatca aggaggagtc atatggcaag ttatatcgaa ccgattcgtt ttgcgctgat
    17521 tgtttttcca tttttagcct tagcgatctc atctgttttt tttatttatg aatatcgaaa
    17581 gtatggaaca tttctagtaa caagggcagt tattttgtat tctttcgttt tttatttatt
    17641 gtgtgcgtat tttttggtga tcttaccact tccggcaaag gagacggttg cccaaatgac
    17701 agggccaaag atggagctgc atttatttgc ttcatggcaa catttcagag acaacacggt
    17761 attggtcttg tctgaaccta gtacctacct gccggcaatg aagcagagtg tatttttgga
    17821 accagctttt aatgttttat tactcatacc atttggcatt tatttaagat attatttccg
    17881 gctttctttt atgaaaacga tgattgctag tttctgcctt tctctatttt ttgaattgac
    17941 gcagctaagt ggactttatt ttatctaccc aagaccatac cgcttatttg atgtgaatga
    18001 tttagtgaca aatacattgg gtggaatcat tggttttgtc gttacgccgt tatttacatt
    18061 tatgcttcct acaagaagac gaatggatga actttcttat gaaaaaggaa agactgtctc
    18121 attgactcga cgcttggtcg cttatttgat cgactggaca tttttatctc ttattaattt
    18181 ggtagcggcg attttcttta aaattgcgtt cgattcaggg gcagttactt ctcatatctg
    18241 gtggctttta ttagaagtag gggtatactt tatgattgta ccgtttataa ccaatggatg
    18301 gacacttggc aaaaaaattg tgcgtatccg tttggtggaa gaagaccgcg aacgaatttc
    18361 tttaaaagca ttgatgatcc gctacgggta tctgtacttt cttttttatg gtttaagctg
    18421 gttggggcag ttgcttcagc aaatcatgaa ttcgacaacg aatacggtgt tgcagatgag
    18481 tgcagtattc atttctctcg gtgtcttgtt actacaaggt atttttattt taaatatctt
    18541 gctatcattt ttgagaaaaa aacggattct gttttatgaa aaagctagtc acacatatac
    18601 tgttagcacg attggccaaa caaaggatga tgattctcga aattagctga gcaaaaacgc
    18661 tttgtctgtg ttataatgcc aaagtcgtga taatttaaag agaagaggtg cacgaatgaa
    18721 taattttgat atattccgct tcaaaccgtt tatcaatgaa gcgttaaccg caaagggctt
    18781 caaacagccc acagaggtcc aggaacgttt gattccttta attgcaaaag gaaaaaatat
    18841 cattgggcaa tctcaaactg gtacaggaaa aacacatacg tttttgttgc ctttgtttga
    18901 aaaaatcaat gcagaaaaag aggaagtaca agttgttatt acagctccaa gtagggaact
    18961 agctgcacag atctatgaag cagctacaca aatcgctaaa ttttctacac cggagatccg
    19021 tgtctcgaat tttgtcggcg gtacagacaa acagcgtcaa ttaaatcgtc tgcatcacca
    19081 acagccacag gttgtagtag gcacgcctgg tagaatatta gacatgatga atgaacaagc
    19141 gctgaagatt cacaccgcat ttgcatttgt tgtcgatgaa gcggatatga cattggatat
    19201 gggtttttta aatgaagtag accaaattgc aagtcgatta ccagaaaagc tgcagttttt
    19261 agttttttct gccactattc cagaaaaact tcgtccattc ttacgaaaat acatggaaaa
    19321 tccaatcatt gaagaaatca aaccaaaagc agttatttct gaagacattg aaaattggct
    19381 gatttcaaca aaaggtaaag atgagaatca aatgatttat caactgctga caattggtca
    19441 tccttattta gcaatcgtat ttgccaatac aaaacagcat gtggatgaaa ttgccgatta
    19501 cttgaaaaac caaggcttga aagtagcaaa gattcatgga gacatcaccc caagagagag
    19561 aaaacgagtg atgcgacaag tacagaatct ggagtatcaa tatgttgtag cgactgattt
    19621 agctgctaga gggatcgata tcgaaggtgt ctctcatgtt attaatgcag aaattccaga
    19681 agatctagac ttctttatcc atcgtgtcgg acgtactgga cgtaatggct taaaaggaac
    19741 ggccattacg ttatattcgc caaatgatga gcaagccatt gatgcgatag aaaaattggg
    19801 cgtctcattt gaaccaaaag aaatcaaaaa cggggaaatc gtcaaaacat acgatcgtaa
    19861 tagacgtgcc aaacgagaaa aatcaaaaga tgtattagat cccacgctga ttggtcttgt
    19921 gaagaagaaa aagaaaaaga tcaagcctgg ttataagaaa aaaatcgatt gggcaattgc
    19981 agaaaaaaat aaaaaagaac gcaaaatcga acgcagacag caaagccgta ctgctcgtaa
    20041 aaataagaaa aattcacata aataaaaaac aagaggttgt gacaaaaggc gtgtcacaat
    20101 ctcttgtttt taagctagac tttttttcat tccgatacaa agtacttcat cttcaataaa
    20161 aggttctgtg caagtatgat acccttgttt ttcataaaaa tctacagccg tcatttcagc
    20221 tactacataa ctagtctgac aaccttctga aaccgcccgt ttttcagcag cttcaagcaa
    20281 ctgaccgcct aacccttttc ctcggtattc ttttgctacg caaaatcgtt ccggcttgaa
    20341 gcaagtaggt gttttctttt cataacgcaa agtagctact ggtctttttt gatcaagaaa
    20401 tagataatag gtttgttgcg ggatatcttt tccgtcgaat tctagttctg caggaatccc
    20461 ttgttctaat acaaaaactt gatatctcaa aaagcagcta gctgcgcgta tccattcatc
    20521 cgctccaact atttttttca tcatattcct ccttgtcatg aatagcagag atgtattgat
    20581 tcctttattc ttatcgtacc aaaaatcgtg gagtatgacc aaaaggaaat gaaaataaaa
    20641 attgagatat tgacagtgat caatagaatg cgtatactaa ttaagtacga aaaggatatg
    20701 atttgttttt taagactcac agaaaattct ttcttggctg aaaaaagaat agtcactaat
    20761 caaattgctc cctttttcta ttttggtaga aataccgacg cagctcagcg ttatcgagtt
    20821 taagaggtaa tgattacaca tcattgcaat caaggtggta ccgcgagttt tcgtccttgg
    20881 ctgtgatggt gtttttttgt atttaattta tagaaagcag gtaatgacat gaaacaatta
    20941 agtagtgcac aagttcgaca aatgtttctt gatttcttcc aatctaaagg acatacgatt
    21001 gaacctagtg cgtctttgat ccccgtgaac gatccaacct tattgtggat caactctggt
    21061 gttgcaacat tgaaaaaata ttttgatggt tcagttgtgc cagaaaatcc aagaatcaca
    21121 aatgcccaaa aatctattcg aacaaatgat atcgaaaatg tcggtaaaac agcacggcac
    21181 catacgatgt ttgagatgct gggtaatttt tcgattggtg actatttcaa aaatgaagcc
    21241 atccactggg catgggaatt tttgactgat ccaaaatgga tggcattcga tccagaaaaa
    21301 ctttatgtaa cagtttatcc aaaagataca gaagcaaaac gcatctggca tgaagaagtt
    21361 ggcctgccac tagatcacat tattgatgta gaagacaact tctgggatat cggtgcaggc
    21421 ccatgtggtc cggatacgga aattttctat gaccgtggag aagcttataa cgatttagca
    21481 gaagacgatc ctgaaaacta tccaggagga gaaaatgaac gttatttaga aatctggaac
    21541 ttagtatttt cagaattcaa ccataagcct gataacacat ttgaaccact tcctcataaa
    21601 aacattgata cggggatggg attggaacgc atggtctcaa tcgttcaaga tgcgtcaacg
    21661 aactttgaga cagacttgtt tatgcctatt atccacgccg tagaaaagct aagcaaacaa
    21721 gtaaaatatg gtgaaaaccc agtaacagat atttcttaca aagtaatcgc agatcatatt
    21781 cgcgcccttt catttgctat tggcgacggt gcattgccat cgaatgaagg gagagggtat
    21841 gtcttacgcc gtttgcttcg tcgtgctgtc atgcatggga aaaaattagg tattgaacaa
    21901 gcattcttat atcgtttagt ccctgttgtt ggggaaatca tggtaagtta ttatcctgaa
    21961 gtacttcaac aaaaagaatt tattgaaaaa gttatccgta cagaagaaga acgtttcaat
    22021 gaaacaatca atgaaggttt ggaaatctta aatcaagtga tccaagaagt aaaaaacgaa
    22081 aacgggacga ctctagcagg aaaagacatc ttcaaactat acgacacata tggcttcccg
    22141 gtagaattaa cggaagaggt ggcagaagat gaaggactga aagttgatca tgctggtttt
    22201 gaaaaagaaa tggatgcaca acgcgaacgt gctcgctctg cccgcagtac tgaaaaatca
    22261 atgggggtac aatctgcttt attgacagat atcaaagtag aaagtaaatt cattggatac
    22321 acagaacaag aatcagatag tcaattattg gtcatcgtta aaggtgagtc tcttttgaat
    22381 gaagtcgcag aaggtgaagc tcaaatgatc tttgatcaaa cacctttcta tgcagaaatg
    22441 ggtgggcaag tagcggatca aggatggatc atgaatgaag taggcgaaat cgtagcagtt
    22501 gttacagatg ttcaaaaagc gcctaatggt caatttatgc acaccgtaga agtaaaagca
    22561 ccaatgagtg aaggacaaac ctatcatcta ttgatcgatc aatcgatgcg caatcggatc
    22621 atcaaaaacc atacagcaac ccatctactg cacaaggcat tgaaagaagt acttggcgag
    22681 catgcaaatc aagctggttc tttagtcgct cctggacatt tacgattcga ctttacccac
    22741 tttggtcaaa tcacttcaga tgaattagct gaaatggaaa gaatcgtcaa cgaaaaaatc
    22801 tgggaagcta tcccagttga aacaattgaa acagatatcg atacagccaa aaacatgggt
    22861 gcaatggctt tgtttggtga aaaatacgga catgacgttc gagtagtaaa tattggcggc
    22921 tggtcaatcg aactgtgcgg aggcacacat gtagcaaata cagaaaacat cggaatcttc
    22981 aaaatcgttt ctgaatcagg aattggtgca ggcgtgcgac gaatcgaggc tgtaacaagt
    23041 aaagaagcgt acgaactact tgaagaagaa gaaaaacaac taaaacaagt agcaacaatt
    23101 gttaaatcac ctcaattgaa agaagttgtt tcaaaagcgg aacaattgca acagcaagta
    23161 agagagctac aaaaggaaaa tgaacaatta gctagcaagt tagcgaatca acaagctggt
    23221 gatgtattca aagatccaga aacgatcaat ggaaaaacaa tcattgcagc acaagtaaaa
    23281 gtgaaagata tgaatcagct gcgtcaatta gctgaccaat ggaaacaaaa aaatatttca
    23341 gatattcttg ttttagcaaa cgaacaagaa ggaaaagtca gtctgctagc ggcaatgacg
    23401 aaagaatcaa atgaagctgg actaaaagct ggcgacttga ttaaagcaat cgcaccgaaa
    23461 gtaggcggtg gcggtggtgg acgtccagac atggcacaag ctggcgggaa aaatcctgct
    23521 ggtattccag atgcacttaa agctgcgaaa gaatgggttg cgcaacaata gggcgtttac
    23581 gtttgacaga aaaacaaaag ttcaaacatt gaacgaaaca tgattatggg ggcgaagaca
    23641 aacaagtctt gccctcatac ttttttcaat tggatggcgc atctaatcaa atggtcggat
    23701 tcggatggtc tttagttgac gaaagtgaca gaaattttta cgattagtat aaataaaaag
    23761 gggtgaaaaa atgaatagta gaaataagac ctttcgacta gtcttacgtg cgatcttgtt
    23821 agcaatcatc atcgtacaag cgatggttcc ttggctgggg tttattccat taggattcat
    23881 tagtttaaca attatccata tcacagtaat tattgctgca gtagtattag gcccaaaaga
    23941 tggcatggtg attggcttgt tttggggaat cgctacaatt gttcgtgcct atgccatgcc
    24001 aacaacgcca tttgatacat tagtgttcac gaatccgatt atctcggtag ttcccagagt
    24061 acttgttggc ttagtagcag gcttggtttt ccactggatt tatcaaaaaa ataaatcaat
    24121 aacgatcagc tcagcctttg caggggtact gggttcattg gtcaatacag tcttagtgtt
    24181 aggattcatg ggattatttt atacaggtgc aacggcagat gcctatggtg tagactctgc
    24241 tcttttattt aaaaccttag caggggttgc agcaatcaat gggataccag aagcaatagg
    24301 tgcgggaatc ataacaccat tactagcaaa agcgttattt gcagcaacac cgttgaaacc
    24361 agaataatga ccatctttta atagtaatag gacgcacgat agatagaaaa aggaagagag
    24421 gagaggaaaa caatcgtcct ctccatcttt ttacctgagc aacaagcaaa ctagaagggg
    24481 taaaaaactt ggctaagaaa caagaagaaa aaaagaaaca aataccgcaa cagcggacaa
    24541 aaaaaggagt actagcgggt atcttaggat tggttacgaa tctgatcttg tttgtctcta
    24601 agctaatgat cgggcttttt tcaggaagtg tctccattat ggctgatgca gtgaacagtc
    24661 tatcagatac tgcttcatcc atattgactt tgatcggatt taaaattgct gcaaagccag
    24721 cagatcagga acatccttat ggacacgaac gcttcgaata tatcagtggg ttatttgttt
    24781 cgatcatcat tacttatgta ggatttcaat ttttagagtc ttctgctgaa aaaatcatcc
    24841 atccagaaaa tgtctcttta acacccatcg tcttttttgt cctaatcatt tccatctttt
    24901 tgaaatttgc acaaggcaaa atgtatcagg ttattgcgca atccattgat tctgaaacat
    24961 tgagagctac agcaacagat agttataatg atgtctttac tacactggct gtattgcttt
    25021 cagcagcaat cgaatgggta actggatggc gtattgatgg atatataggt tttgctttag
    25081 cattatatat cctttatagt ggattgacga tgcttcgaaa ttttgtatac gaactattag
    25141 gaagtcgccc aacgccagca gagattgaag aaatggaaga gcatttaaat gcttgcgatg
    25201 atatacttgg ctatcatgat ttattggtgc ataactatgg acccaataaa cgctttgcat
    25261 cagtccacat cgaagtagat gaatcaatga atttgaatgt ggctcataag attattgatc
    25321 tgatagaaaa agactttaaa aagtctttgg atgtggaact tgtctgtcac ttggatccaa
    25381 tgcctgttga taacgaaaaa tactataata tcttgcggca gttaaagcaa attcttcttg
    25441 aaacaggtac agggcttaat attcatgatt ttagagtaat tcatcaagga aaaacgctgc
    25501 aatttgatgt agtggtccct gagaaattcc agtttgttga tacagaacta gaaagaatct
    25561 tacgtagtca aatagaagaa aaaatcggag attaccaatt ggaaattacg tttgatcaca
    25621 attatctttt atattaaatg agaaactata aaaagactcc ttaaagtttt taatttaaag
    25681 agtctttttt tcttttaatt gtttatggag agcctgacgt gcaagattat ctgctccttt
    25741 atttttgttt tcgggcaacc attgcaggat caataaagaa aattcggata gaagttcttg
    25801 gattctttga aggtagggaa ggaagagctc gttcttcgtt gcgtttttgt cgaccgtaga
    25861 aactagtgtt ttgctgtctg aaaaacagaa aatcgtttca ttctgtaagt cgtttttctt
    25921 tagaaattct aaagttttta aaaagacttc gaactctgct tgatggtttg tccctataga
    25981 aagcgggata gatagctgtt cttgtttacc ttgatagaca atcaagattc cacctccact
    26041 aggaccaggg ttgccttttg tagaggcatc aatgtatact tttaacataa aaagagattc
    26101 tcctttttgt tcaaactaat gttatggtaa gattatatca ttactgaatc ggtgagaggt
    26161 tagagaatga aaaaaaatat tcgatggcag cctgaactgg cacatacgat catctattgg
    26221 tcattgacct tgatcattct gttttttagt ctgattcttt ctttagaaaa cacaggtcct
    26281 tattggaaaa gcaattttgt tttaggtatt tttcttgttt ttctatttct aggtttgcgg
    26341 cgttctttta ttttaaaatc aaactctgtg attatacgtt atgctgcttt ttggaaagac
    26401 cgagaaatat ctgtcggaca gattcgatct ttgacgccaa ctaatactgg ggtgcaaatg
    26461 atgttgcaag atgagaaagc cccatctgtt ttcatgatgc gaaaaaaaga tcaagtagtc
    26521 ctttttgatc attttgaaaa aaacggaccc aaatcagaat caattcctta tccttatacg
    26581 aaaaaaagaa aaagctaatt ttaaaaatca gaacctaaaa aaacgaattt ttacaggaaa
    26641 agaaaagagt gagacgtacg gttcatcccg tttagcgtct cactctattt gtttatctat
    26701 tcatgcatac tagtatcggt agtctgaacg ttgcctttct tgacatgggc agcttgtgtt
    26761 cctcgattcc cttcgatgat ctcaaattcg accacttgat tttcttccaa agttttgaat
    26821 ccctcttctt caatcgcagt aaaatgtaca aaaatttctt ctgtgtcatc ataactgata
    26881 aagccgtatc cttttttgtt gtcaaaccat tttacaattc ctgtggtcaa agcactcacg
    26941 acctttctaa agtctgatca tagccttcat tataaagagt atttataagt acgtcaaata
    27001 aattaaaaac ctgtaatttt atgttttttt tctgaataaa aaaaggtata attggcatat
    27061 cttaacaaag aagatatttt gttgaataaa gttcgtgaaa aggggtaatc aaatgaagaa
    27121 tgatctgcaa atttcacaag aaacagagct agaaccgatt gttgaagtgg ctagtaaatt
    27181 agatcttaag gaagacgatt tggaactgta tgggaaatat aaggcgaaaa tcaatttttc
    27241 tggaatcaat cgatcaaagg ataacgctga ggggcatttg atcttagtta cttccatcaa
    27301 tccaacacca gctggcgaag gaaagtcaac gatcactgta gggttaggag acgcgctcaa
    27361 taaaatcaat aaaaaatctg ttattgcatt gcgagaaccc tcacttggtc ctgtgatggg
    27421 aatcaaaggt ggtgctgcag gcggaggata tgcacaggta ttgcctatgg aagatatcaa
    27481 cttgcatttt actggtgaca tgcatgctat cacaacagct aataatgcat tatctgctct
    27541 tttagataat catattcatc aaggaaatga attgaacatc gatgcccgcc gagtgatttg
    27601 gaaacgggta gtcgatctca atgatcgtga actgcgtaaa gtaattgttg gcttgggtgg
    27661 gccaatccaa ggtgttccaa gagaagatgg gtttgatatc acagttgcca gcgaaatcat
    27721 ggctatcttg tgtcttgcgg cagaccttga agatttaaag gctcgtcttg caaggatcgt
    27781 tgtcggctat acatttgacc gtcagcctgt gactgctgga gacttgaaag cagaaggcgc
    27841 tctggcatta ctgctgaaag atgcaatcaa gccgaatctt gtacaaacaa tttacggaac
    27901 accagctttt gtccacgggg gaccgtttgc caatatcgct catggctgca atagtatttt
    27961 agctaccaag acagcattga gattagcaga ttacgttgtc acagaggcag gatttggtgc
    28021 agatcttggc ggagagaaat ttttagatat caaagtacct aacttgaaaa aagcgccgga
    28081 tgctgtggtg attgtcgcca ctgtccgtgc attgaaaatg catggcggaa tgaaaaaaga
    28141 tgaacttaaa aatgagaatc ttgatgcttt gaaagtaggt tttgcaaatt taaagcgcca
    28201 tatacgtaat atggaacaat atcagctacc tgtgatcgtc gcaatcaatg aattcgtaac
    28261 agatacagac aatgaactca cactgttgga gcacttgtgt gaaaatcagg ggattcttgc
    28321 caagagagcg agtgtatggg cagatggagc agaaggcggc gttgatttag caaaagctgt
    28381 agtacgattg attgatagaa aagaagctaa ttacaagcca ttataccgcc tagaagaaac
    28441 gatacaagaa aagacagaaa caatcgtcaa gaaaatttac ggaggaaatg gtgttgtttt
    28501 cagcaaaaaa gcgcaaaaac aaatagaaga gtttacgaag aatggatggg acaaactgcc
    28561 gatttgtatg gcaaaaacac agtattcatt ttctgatgat ccttcactgc taggtgcacc
    28621 ggaagatttc accatcacga tccgcgaaat catcccaaaa ttaggggcag gatttttagt
    28681 agccttgact ggagatgtta tgacgatgcc tggtttgcct aaaaaacctg ctgcattgaa
    28741 tatggacgtg acaaatgacg gagaagtgtt gggattgttt taagcttgat tataatctac
    28801 catcgaagga gctgtatttt gactacagct tcttttttta gacgataggg aattaatttt
    28861 gtttacacta ggatcattct ttttctttat tgtattttga gctatactaa agcataatag
    28921 gagggtatga tgaaaacgac atttataaga aaaaccggtt tttacggtat gggtagctcg
    28981 attcagctaa gaatcaacaa tgaaaaacgc agtgttctca gtcatgaaca aaagataacg
    29041 cttgatctgg aagtgccctt tacgatgcag gtcacctttt attggctaaa aagccccgtt
    29101 tatacagtga aagaagcaaa gcctgcttat gtgatcacaa tgaattactt gattcttcaa
    29161 atctatccgt ttttatttct agcaactggg ttgggggccg ttttcctaca aaatttattt
    29221 ttcagttttt ttgcagttat tgtgttgatt gcgttctttt tctatataaa aaaccgggca
    29281 tatttgatca aggaggaaaa ttatggcaaa ctctgatctt tttttaatca gtttcaatcg
    29341 aatcgaaaaa tggatgagag acgagatggg aaatgcacga aatatgggat ttaccgaact
    29401 tgtcagacgc ctagctcaaa gaaaacaatt aatgatcaga aaatacgaag atgatctttt
    29461 acagcttgct cagttaagga atgcgatcgt ccatgatcgg atcgcagtcg attttgtcat
    29521 tgcagagcca aatgattgga cagtcaagcg aatccagctg atcgaacaag aactgattca
    29581 gcctgaaacc gtgctgcctc gatttgcaaa acgtgtaaca ggttttgaac aagatcttcc
    29641 gttacttgaa ctgttaaaga tagtagcaga aaaaaggtat tcacaatttc cgttatacaa
    29701 taaaggaaaa tttgtagcat tgattacttt acgtaatatc gggttttggc tagcaaaaga
    29761 aagccaaaaa ggtccggttg atttaacaaa taaacgagcg ttggatttga tcatccaaaa
    29821 cggaaagtac acaaattatc attttgttcc agctaaaaca catatttacg aggttgaagc
    29881 gatgtttcgt gagcaaggga ctttggaagc cgtacttatc actaaagatg ggaatcccga
    29941 tggtaatctg ctcgggatcg tacgacctcg tgatatttat aaacaaatag aaaaggattg
    30001 attttttgtt aattatttat tggatattca gcgctttgct agtaggagtg gatcagttgg
    30061 tcaaatggtg gatcactgat aatctagcgc ttggagagac gaaaaatctt ataccaggta
    30121 ttttgtcact gaatcatatt cgaaacactg gagccgcatg gagtatgcta gaagggaaga
    30181 tgtggttctt tactatagtg acactcattg cagtcgttgt gattctcaca ttgatgatta
    30241 aaaatcgtga aaaaggtaat cgctggttca tgattggatt gagtttgatt ctagctggtg
    30301 cgattggcaa ttttatcgac cgtattcgtc ttggctatgt agtagatatg ttccagacag
    30361 attttatgag ctttccgatt tttaacgtag cagatgtgac acttgtatgt ggagtgattt
    30421 gtatgttaat ttatattatt ttagatgaaa aggatcaaag aaaaaaatga cagaacttaa
    30481 aacgacgatt caccatgaat ctggtaggat cgataaagta ttgactaatt tattcaccga
    30541 ttacagtcgt tcgcaaattc agctgtggct gaaaaatgga gcggtttctg tcaatggaca
    30601 gccagtcaaa gcaaattaca aagtaaaaca aggagacgag attactgtct tgatccccga
    30661 accagaaaca ttagatgtgg tcccagaaaa tatcccgttg acgatcgttt acgaagatga
    30721 agatgtagcg gtgataaaca aacctcaagg aatggtcgtt catccttcag caggtcatac
    30781 gcatggcaca atggtcaatg cgctgatgta ccatatcaag gatctttcta cgatcaacgg
    30841 cgttattcgt ccaggtattg ttcaccgaat cgacaaagat acttccggac tgctaatggt
    30901 tgccaaaaat gaccaggcac acgaatcatt agctcagcaa ttaaaagata agacctcttt
    30961 gcgcaaatat gttgctttag tccatggaga gattcctcac gaaaaaggaa ccatcaatgc
    31021 gccaatcggc cgttcgaagg aaaaccggaa aatgcaggcg ataagagaag atgggaagtc
    31081 ggctgtcaca cattttactg tattggaacg tttcgaagga tttactctgg ttgaattaaa
    31141 actagaaacc ggaagaacac accagatccg tgtgcatatg aagtatatcg gttatccgtt
    31201 agctggagat ccagtatacg gaccgaagaa aactttgaaa ggcaatggtc agtttctcca
    31261 tgcgcaaatg ttaggtttta cgcacccgac tacaaacgaa aagatgatct ttgaagcacc
    31321 tcttccagaa gtttttgaaa aaactttaga aaaattaaga aaaaacattg cattttaatt
    31381 tagataacgg tatagtaatt aacaacgaaa gcataaaact taatagaatt cctttaagtt
    31441 tagtcccgtg aggctaagaa gggtgggagc aaggatacgt atggtgcgcc ataagtagat
    31501 tgctcattga catagtatag ctatcagtgt atcagtatac gctcagtcta aacattcctc
    31561 ctgtcctctt agggcaggag tttttttatg caaaaaagta gggggaatga aaatgcaagc
    31621 aaaagaagta gtagatcagg taaccatgaa gcgagcattg actcgaatta cttatgagat
    31681 tatcgagaga aaccatagta tccaagatat cgtattggta ggtatcaaaa cacgaggaat
    31741 ctacattgca tcaagaattg ccgaacgcct gaagcagcta gaagatatcg atattcctgt
    31801 aggagaactg gatatcactt tataccgaga tgacaaaaaa gaaaatccag aagaaccgga
    31861 acttcattct tctgacatcc cagtttcctt agaaggaaaa gaagttattt tgattgatga
    31921 tgttttgtat acaggacgaa cgattcgagc agcaatggac gcagtaatgg attttggcag
    31981 accaagaaaa atttcattag cagtcctggt cgatcgtggg catcgagaat tgccaatccg
    32041 tgcagattat gttgggaaga acattccaac atctcgggcg gaagagattt tagtagagat
    32101 gcaagagctt gatggacaag atcgcatcat gattttgaaa gaggaagatt agaggagaga
    32161 gaaacatgtc ggagaaaaaa ggatttcata atgatgacgt ggtgttagat atccacgatc
    32221 gcccaacccc aggacattgg gtaggattaa gtttacaaca cttgttcacg atgttcggag
    32281 caaccgtgtt agtccccatc ttagtaggta tcgatccagg tattgcgcta gtcagttcag
    32341 gactaggtac attggtgtac ttatttacta ctaaaggaaa gatacctgcg tacttaggaa
    32401 gcagcttcgc tttcattgca gcgatgcagc ttttgatgaa aacagatggt tatccagcga
    32461 ttgcacaagg agcagtcaca actggattag tctatttgat tgttgcgctg atcatcaaaa
    32521 agatcggttc agcatggctg gataaaatct tgcctccaat cgtcgtcggt ccagtcatca
    32581 tggttatcgg gttgggactt gcggcaaatg cagcaacaaa tgctatgtat aatcagggca
    32641 cgtatgattt caagtatatt gctgtagcgc tgatcacatt aggattaaca attttcttca
    32701 acatgtggct aagaggtttt ctcggattga ttccgatttt actaggtatt attagcggat
    32761 acatcgtagc cttgctgttt ggaatcgtgg atactaagcc aatcgtagac gctgcctggt
    32821 ttgctgttcc taactttgag attccctttg tacaatatga accaaagcta tatcttggag
    32881 caatcacaac aatggcaccc atcgcttttg tgacgatgac agagcatatc ggccatctta
    32941 tggtattgaa taaactaact aaacgtaatt tctttgaaga accgggtctt cataagacgt
    33001 tgacaggtga tggattagca caaatcgtgg cagcctttgt cggaggtcct cctgtaacaa
    33061 gttacggtga aaacattggt gttctggcta tcacacgtgt ccatagcgtg tttgtgatcg
    33121 gtggagctgc agtatttgca gtcattttag gattcgtagg aaaattaagc gctttgattt
    33181 taagtatccc tggaccagtc atctcaggaa tcagttttat cttatttgga gtaattgccg
    33241 caagtggaat gaagatttta atcgagaaca aaatcgattt tgataaaaag aaaaatctgt
    33301 tgattgcttc agttatctta gtagtaggaa ttggcggact cgtctttgaa gtaggcacat
    33361 ttacattgtc ggcaatggca ttagcaactg tacttggcat cattttaaat cttatcttac
    33421 cagaaacttc acgaagcgaa gaaaactaag gaggaaacat tatgatcatc aaatcagaac
    33481 gtatcagctt aaagcattta ttgaccgttg aggcacttac tgatcaagaa gttatgggct
    33541 tgatccgcag agggcaggaa ttcaagcaag gtgctaattg gactccgcaa aagcgccagt
    33601 actttgctac aaacctcttt ttcgaaaata gtactcgcac acataaaagc ttcgatgtag
    33661 cggagaaaaa actagggcta gaagtgattg aatttgaagc aagcacaagc tctgtccaaa
    33721 aaggggaaac actatacgat acagtactga cgatgtcagc attaggcgta gacgtagcgg
    33781 ttatccgtca tggtgatgag aactattatg acgaactgat acaaagtaaa acaatccagt
    33841 gttcgattat caatggagga gacggaagcg gacagcatcc aacccaatgc ttgcttgatt
    33901 tgatgaccat ttatgaagaa tttggtcatt ttgaaggtct gaaagttgcc atcgtaggtg
    33961 atatcactca ctctcgcgta gctaaatcca atatgcagat gttaaaacgt ctaggcgcac
    34021 aagtattctt ctcaggtcct agagaatggt acgacgatga attcgaagtg tacggacatt
    34081 atatgccatt ggatgaacta ctagatcaag ttgatgtcat gatgatgctt cgggtgcaac
    34141 acgaacgcca tgatggaaaa gaaagtttct caaaagaagg ctaccatcag gaacatgggt
    34201 taacagttga gcgtgcgaag aagttgcaaa aacatgcaat cattatgcac ccagcaccag
    34261 ttaaccgtga tgtagaatta gctgattcat tagtggaagg attacagtcg cggatcgttc
    34321 agcaaatgag caatggagta ttcgtcagaa tggcaatctt agaagcagtg ctaaatggaa
    34381 aagcgtaatt ataggaggat gaaaaaatga aaacactcat taaaaacggt cagatcaata
    34441 cacgaaaaaa tatgacgaca ccagcagaaa tttggataga agatgggcga atcaaagcaa
    34501 tcggtacagg attctcagaa gccgaatttg atgaagtgtt tgatgcaaag ggacaattga
    34561 tcacacctgg tttagtggac gtccatgttc atttgagaga gccaggattt acatacaagg
    34621 agacgatcga agctgggact cgctcagctg ctcgtggcgg tttcactact gtatgcgcga
    34681 tgccgaattt aaatcctgta cctgatacgg cagaaaagct gagacaagta tatgacatca
    34741 ttagaaaaga tgcagttgtg aaggtattgc agtatgcgcc aatcacagaa aatctgcgaa
    34801 gtgagaaatt agttgatcaa gaagcactga ttgaagaagg tgcttttgct ttcacaaatg
    34861 acggtgtagg tgtccaaaca gctgggacga tgtatctggc tatgaaagaa gctgcaaaaa
    34921 acaataaagc cctagtagcc catacagaag atgaatcttt attatttggc ggcgttatgc
    34981 acgctggcaa gaaggcagaa gaacttggtc ttcccgggat cttaagcgta accgagtctt
    35041 ctcaaattgc tagagatctg ttgctagctg aagcaactgg tgttcattac catgtttgcc
    35101 atgtttctac taaagaaagt gtccgtgtaa tcagagacgc aaaaaaagca ggaatccacg
    35161 taacagcaga agtttcaccc catcatctta ttttgatcga cgaagatatt cccgaagatt
    35221 tcggcttttg gaaaatgaac ccgccgctaa gaggacggga ggacagagaa gctttgatcg
    35281 aaggcttgct tgacggtacg atcgattgca tcgctacaga ccatgccccc catggattag
    35341 aagaaaaaag ccaaagtttc atgaaatcac catttggtat cgtaggaagc gaaacagcgt
    35401 ttcaactgat ctatactcat tttgtagaaa ctggtcgatt cacgttggaa caagtgatca
    35461 attggttggc agttaaaccg gctgagattt ttggtttgaa tgcaggaacg ctaacggttg
    35521 gtgcccccgc tgatgtagca gtttttgata ttacacaaac ttgcacgatc gataaagaag
    35581 actttttatc aaaaggggag aatacacctt ttatcggctg gaaagtaaaa ggcgaaacac
    35641 aaatgacttt tgtcaacgga aaacttgtgt ggcagaaggg agaataaaag tatggaacgt
    35701 ttgcttatat tagaagatgg aacagttttc gaaggaaagg cttttggtgc agatgctagt
    35761 gtcttcggag aaatcgtttt tacaacaagt atgactggtt atcaagaaac tatcactgat
    35821 caaagtttta acggtcaaat cattacattt acctatccta tggtgggtaa ttatggggta
    35881 aatagagatg attatgaatc gatttctcca acatgcaaag gagtagtagt aaaagaacat
    35941 gcacgtgtag cttcaaactg gcgaaaccaa atgacgctag attcattttt gaaacaaaaa
    36001 ggaattcctg gaatatcagg tatcgatacg cgcgccctta ctcgcaaaat ccgtgaagtc
    36061 ggaacgatga aagctagtat cgttgatgct ggagattcct tcgaacatgc atttgatcag
    36121 ctgaaagcaa ccgttctagc aaccaatcaa gtgcagcaag tctcaactaa caaaccttat
    36181 ccaagtccag gaacaggtcg gaaagtcatt gtcattgact tcggcttgaa acatagtatt
    36241 ttacgagaat tgagtaaaag aaactgtaac ctcacagtac ttccctataa cacagatgcc
    36301 gagacgattt tagcgctatc accagacgga gtcatgctga cgaatggacc tggtgatcca
    36361 aaagatgtgc cagaagcaat cgaaatgatc aaaaaaatcc aaggaaaagt accgattttt
    36421 ggtatttgtc tcggtcacca gttatttgct ttagccaacg gtgcagatac ctataaaatg
    36481 aaattcggac atcgaggatt aaatcacccg gtacgagaag tagcgaccgg aagaattgat
    36541 tttacttctc aaaatcatgg ctatgcagtc gatgaagcca cgattgatcc agaaaaactc
    36601 atcgtaactc atgtagaagt aaatgacgga acagtagaag gagtcaaaca cagagattat
    36661 cccgctttca gtgtgcagtt tcatccagat gctgcccctg gtccgcatga tgcactacat
    36721 ttatttgatg aatttatgga aatgatggac gcaggaaagg agcagtaaac agatgccgaa
    36781 acgtacagat atcaagaaaa ttatggtgat tggatctggt ccgatcatca ttggtcaagc
    36841 cgcagaattt gactacgcag gaacacaagc ctgccttgcc ttaaaagaag aaggatatga
    36901 agtggtttta gtaaattcta atcctgcgac gatcatgacg gataaagaag tggcagatca
    36961 agtatatatc gaaccgatca cacttgaatt tgtatcaagg attcttcgaa aagagcgtcc
    37021 agatgctctc cttccaactt taggcggaca gacaggcctc aatatggcaa tggagctggc
    37081 agcatcaggt attttagaag aattgaacat agaacttcta ggaacaaagc tttctgcgat
    37141 cgatcaagca gaagatcgtg atctattcaa acagttgatg aaagaattga atcagccaat
    37201 ccccgagtct gaaatcgtca atacagtaga agaagctgta gattttgcaa ataaaatcgg
    37261 ctatcctgtc atcgttcgtc cagcctttac tttaggcgga actggtggag gtatgtgtga
    37321 aaatgaagaa gaattacgta tcgtatcaga aaatggatta agtctttccc ccgctaccca
    37381 atgtttgatt gaacgaagta ttgcaggttt taaagaaatt gaatatgaag tgatgagaga
    37441 ttcggctgat aatgcaatcg ttgtctgcaa tatggaaaat tttgacccgg tgggtatcca
    37501 tacaggtgat tctatcgtat ttgcccctag tcaaacattg tctgaccatg aatatcaaat
    37561 gcttcgtgat gcttctcttt cgattattcg agcacttaag atcgagggag gctgtaatgt
    37621 ccaactcgct cttgatccac atagttttaa ttattatgtg attgaagtca atccgcgtgt
    37681 ttctcgttca tctgcgttag caagtaaggc gactggctat ccgatcgcta agctagctgc
    37741 taaaatagcg cttggattaa cattagacga aatgaaaaat cctgttacag gaacgacttt
    37801 tgcagaattt gaacctgcat tagattatgt tgtagctaaa attcctcgct ggccgtttga
    37861 taagtttgaa aacggagaac ggcttttagg cacgcagatg aaagcaactg gtgaagtgat
    37921 ggctatcggt cggaatatcg aagagtcttt attgaaagct gtgcgttctt tagaaatcgg
    37981 tacacaccat atcgaacttc ctgagttggc agacatcacg gacgatgacc taatccaaaa
    38041 agtggttcga gcacaagatg atcgcctgtt ttatgtagct gaagctatta gaagagggta
    38101 caccatagaa gaattagcgg atttgacaaa aatcgattta ttctttttag ataaactgtt
    38161 gcatatcgta gaaatcgaac agcagttgaa acagcagccg ttggatgaca agatattgaa
    38221 aacagcgaaa caaaacggtt ttacagacaa aaaagtggcg gagctgtggg aaataaacga
    38281 agaagccgtt cgccagatga gaaaagaaaa tgatttgatt cctgtatata agatggttga
    38341 cacttgtgca gcggaattcg aatcaaaaac accttatttt tatagttcct atgaatatga
    38401 aaatgaaagt tcacgatcag aaaagccctc aattctagta ctgggatctg gtcctatccg
    38461 tatcggacaa ggggttgaat ttgactatgc gactgtgcat tctgtcaaag caatccagca
    38521 ggcaggatac gaagcaatca tcatgaacag caatcctgaa acagtttcga ctgacttttc
    38581 tatttcggat aaattatatt ttgagccatt gaccttcgaa gatgtgatga atgtgatcga
    38641 gctagaacag ccgataggag taatcgttca atttggtggt cagacagcaa tcaacttagc
    38701 cgaacctttg actgctgctg gtgtaaaaat cttagggaca acgatcgaag acttggatcg
    38761 tgcggaaaat cgtgatttat tcgagcaagc gctgaaagag ttggatattc ctcaaccttt
    38821 aggggatact gctacaagta aagaagaagc cgtggttatc gcttcgagaa ttggttatcc
    38881 agttcttgtt cgtccaagct atgtattagg cggacgtgcg atggaaatcg ttgaaaacca
    38941 gcgagattta gaagattaca tggaacatgc tgtgaaagca tctccagaac atccagtact
    39001 agtggaccgt tacttgcttg gtggtgaatg cgaagtggat gcgatttgtg acggtgaaac
    39061 agtactcatc ccagggatca tggagcatat tgagcgtgct ggtgtccatt caggggattc
    39121 aatggctgtg tatccacctc aaacattatc tgaatcgatc aagaaaacga tcgaagatta
    39181 cacgatccgc ttagcattag gtttgaattg tgtcgggatg atgaatatcc agtttgtcat
    39241 ccatgaaaat gaggtttatg tgatcgaagt caatcctcga gcaagtcgga ctgttccatt
    39301 cttaagtaag gtgacaggaa ttccaatggc acaaattgcg acgaaagcta ttttgggaga
    39361 gaaactaaag acacttggtt atgaaaacgg actttatcca gaaacaaaag aagttcatgt
    39421 taaagcacct gtcttttctt ttacgaaatt gcagaaagtt gatacttact tagggcctga
    39481 aatgaaatcg actggagaag taatgggatc tgacagacaa ttagacaaag ctttgtacaa
    39541 ggcattcgaa gcttctggat tacacttgcc tgaatatgga gccgtattat ttacgattgc
    39601 ggacgaaaca aaagaagaag cactagaatt agctaaacgt tttacagaaa ttggctatag
    39661 tctgatagga acgaaacata cagctgctta tttcgaaaaa aatggtctgg tcgttgaaac
    39721 agtagcgaaa atttctgagg aagcagcaga aaaaaatgta gtcgacttaa taagagatgg
    39781 taaaacacaa gtggttgtca atacgattga taaagatcgg ggaaatgctt ctaaagacgg
    39841 tttcatcatc cgaagagaag cagttgaaca tggtattcca ttgtttactt ctttagacac
    39901 agcagatgcg atcgttcgag tgatggaatc ccgtgctttt tcaactaacc ctatttaacg
    39961 gcgagcacat gttaagacaa aaagacgaaa aaccgttgca ggaggggaca gatgaaacaa
    40021 gaaatgatgg aaatcgttca gcaaaaacag ctggcaccaa agatttttga aatgacattg
    40081 aaaggtgatc tagtaaaaga aatgcagcaa ccaggacagt tcttgcatat tctcgtgccg
    40141 cgtgcagact tgctattacg ccgaccgatt agcttgaatc atatcgacca cgaaacaaat
    40201 acttgccgta tcatttatcg ggtggaaggt gaggggacta gagtcttctc tactctttct
    40261 gccggagacc atttagatgt catgggtcct ttaggcaatg gttttgattt gtccaatctt
    40321 catacaggag acgaagtatt tataatcggt ggaggaatcg gtgtccctcc tctatatgag
    40381 ttatcaaaac agttagtcga aaaaggaatt aagccaacgc attttttagg ttttgccaca
    40441 catgaagtcg tttattatga aaaagaattt aatcgtctag gagaaacaag aatcgctact
    40501 gacgatggaa catacggtat gcacggaaat gtcggtaatt tattgttagg aacgaagacg
    40561 gaacctacag ctgtttttgc atgtggttca aacgggttat tgaagacagt ggaacagctg
    40621 ttttcttcgc atcaaaatgt ccagttatca ttagaatccc gcatggcatg tgggataggg
    40681 gcttgctatg cttgcgtttg tcatacgccg gaagatgaaa caggaacaaa aagtgtgaaa
    40741 gtttgtgacg aaggaccgat ttttaaaata ggagaggtaa ttatatgaat gagaatcctt
    40801 tagcggtcaa acttcctggc ctagaattaa aaaatcctat catgccggca agcggctgtt
    40861 tcggttttgg caaagaatac ggaaaatact atgatttgaa tcagcttgga tcgatcatgg
    40921 tcaaggcaac gactccaaat gcccgctttg gcaatcccac gccaagagtg gcggaaacac
    40981 catctggcat gttgaatgca attggtttgc aaaatcctgg tctagacgtt gttatgcata
    41041 aacttcttcc agaattagag gagtacaatg agttacccat catcgcaaat gttgctggtg
    41101 cttgtgaaga agactatgta gaagtttgta gcaaaattgg cgaagcacca aatgtgaaag
    41161 caatcgagct gaacatttct tgcccaaatg tcaaacatgg cggaattgct tttggaacag
    41221 attctgatgt tgcttttcaa ttaacacaag cagtaaagaa agtttcttct gttcctgtct
    41281 atgtcaaatt gtccccaaat gtaacagaca tcgttccaat cgctcaggca atcgaagctg
    41341 gaggggcaga tgggtttacg atgatcaata ctcttcttgg tatgcggatt gaccttaaga
    41401 caagaaaacc gattttagcc aatcaaacag gtggactctc cggaccagca atcaagcctg
    41461 tcgctattcg tttgattcac caagtagcaa gtatatccag ccttccaatc attgggatgg
    41521 gcggcgtgca gacagtggat gatgttcttg agatgtttat ggctggagca agtgctgtag
    41581 ctatagggac cgcgaatttc accgatccgt atatctgtcc taaactaatt aaagagctcc
    41641 ctgtgcgaat gagcgaacta ggcatcgaat cgctggaaag attaatcaaa gaagtgagag
    41701 aggaacgtga acgatgaatc aactagacca acgaccaatt attgcattag atttttcaac
    41761 taggcaagag gtagaagact ttcttcgatt tttcccgaaa gaagaaaaat tgtttgtgaa
    41821 aatcggaatg gaattgttct accaagaagg acctgaaatc gtacgttatc taaaagaggc
    41881 tggtcataat gtatttttag atctgaaact tcacgatatt ccgaatacgg tcgaaaaagc
    41941 aatgcgggga ttggcaaagc ttggtgttga tctcacctgt gttcatgccg ctggcggtat
    42001 tcgtatgatg gaggcggcaa tgcgaggatt agaagagggg actccagaag gtggaaaacg
    42061 tccgctactt ctagctatca ctcagcttac ttctacaagt gaagaagaaa tgcatgccga
    42121 tcaactaatc gaagtttctt tagaaaaaag tgtgatccat tatgctagct gtgccaaaaa
    42181 agcaggatta gatggtgtgg tttcttctgc ttgggaagta gaagcgatca aagaaatggc
    42241 aggagacgaa tttgtttgct taactccggg tataagacca gaaggaacag tcgcaggaga
    42301 tcagacaaga gtagtcacac cttctcaggc aaaaaagatc ggctcaactt ttatcgttat
    42361 aggtcgacca atcactcagt caactaatcc ttataaagca tatcaaacga ttcaaacaga
    42421 atggagctaa cctaaaatga atgttgaaca aagtatcgca aaagacttat tagaaattga
    42481 agcagtattt ttaaatccaa gtaatccttt tacatgggca agtggaatca aaagcccaat
    42541 ttactgtgat aaccgaatca cgatgagcta tccaaaagtc cgaaaagaga tcgcaaaagg
    42601 attagcaagc aaaatcaaag aagcttaccc tgaagtacaa gtgattgctg gaactgcaac
    42661 agcaggaatc cctcatgccg catgggtagc ggaaatactg gatttgccaa tggtctatat
    42721 tcgaagtaag gcgaaagatc atgggaaagg taaccaaatc gaaggacgta tatttgaagg
    42781 tcagaagatg gttgtgatcg aggatttgat ttctacaggc ggaagtgtct tggaagcagc
    42841 tgaagcagca aaaagagaag gtgcggatat ccttggtgtt gcggctatct ttacgtatga
    42901 gttgccaaaa ggaaaagcaa atttcgaaaa agccgaaatc cctcttatga cgttgaccaa
    42961 ttattctgta ttgattgaag cagctttaga agatcgttat atcgatgagc aagaattaac
    43021 tctgctaaaa gaatggaaaa aagatcctga aaattggcag atttaagcgc gcttgatgaa
    43081 gatagagaaa tccgatttgt gtctccagaa tcatcaattg gaatagcaaa aatccaaaaa
    43141 ctgattgcga gaagcatctt ttcatcaggt atgaaaagaa acttctatcg tgatcagttt
    43201 ttgatttttt taaaattcat ttttctaaga ctggttagca gaaagaagag aataatctct
    43261 tctctttttt ctattatata tagattttct ctattttttg gtaagggagc tgtttcaaaa
    43321 atggtaaaga gcggaaatgt tgcgaatatc agttatttaa tgatatgata ttcggaaaaa
    43381 gaaatctcaa agggaggtaa cttttatggg gttgaatgaa tttattttag gattgaacaa
    43441 tttagagacg atcacaaggg cacctggatt ttttaaatat acagagcata cagttgcagc
    43501 acattcgtat cgtgtagcat ctattgcgca agttctagga gacattgaag aagcgaatgg
    43561 acaaccgatc gattggaaac tgctctatga aaaatcattg aatcatgact acacagagcg
    43621 ttttattggt gatatcaaaa cgccggtgaa atacgcaagc aaagagttaa gagggatgct
    43681 gcaaacagtt gaagaaaaga tgacggacga attcatcaac caagagattc cagctgagtt
    43741 ccaagaagtt tatcgccgtc ggttgttcga aggaaaagat gaaaccgtag aaggagaact
    43801 attagccatt tcagataagg ttgaccttct ttatgaatct tttgatgaaa tcatcaaaaa
    43861 taacccggaa aaagtttata aggagatgtt cattgaggca gtgactacga ttaaaagctt
    43921 tgaacatcgg ccttctgttc agtatttctt taaagagata tttccggaac tattgaacca
    43981 ggaattttat ggaaaagagg cgtttttaga aaccgtctca acgattgtaa agaaagaaga
    44041 aaaataaaaa tgatatgaga tgcaggggga agtatagttg aaaaagaata tggatgtcga
    44101 atggggctat tctggagaca aaggtccgga aaattgggcg agtttatgtg attggtttgc
    44161 gagaggtgcg gaatttccat tgcagtcgcc tattcatttg accaaggggg aagaaaccaa
    44221 aatagaagga gacacgcttt cctttcatta tcaaaagcaa cggtttactg acaaggaatt
    44281 caaaaacacg attcatttag taccttttga ccaactcagt tatgtagagt tcaagaaaga
    44341 acgctattat ttgacagata ttcatttcca cttgccttct gaacatatca tcaacggaaa
    44401 acaggaagat attgaatttc attttgttca tatgaacagc aaaaaagaga atctagttgt
    44461 gggtgtcatg taccagctaa tggtacagga aggttggctg tataatcaag aaaatgggga
    44521 aagttggaac ttagaaaaac atgagcattg ggtaaatccg gatgtgttct ttccggagca
    44581 aaaaagccat ttccattata ttggctcatt gacaactccg cctaccagcg ggccaatcca
    44641 atggtttgta atggatcatg taggaaaact gaaccaagag tttcttctcc ccttcgatgg
    44701 tcagtatgct cgaccgaaca accgaccaat ccagcccttg aatggaagag aaatttatta
    44761 tttcgaggag tttgagcaat gaatattcag cagatgaaat acgtggtcgc tgtagcaaac
    44821 aatggtagtt tcagagaagc ggcaaagaaa atgtttgtct cccagccaag tctttcagct
    44881 ggtatcaaag aattagaaac cgagttaggg atcacgctgt ttactcgaac gaatcgaggg
    44941 gcatatttaa cagaagaagg gcaagacttc ttaaatcgtg ccgagaaaat attggtccag
    45001 cttgatacat tagaaactca ctatctaacg agtgaaaaga gagacaattt ttcgatcgct
    45061 gcccagcatt atgatttctt aggtcctttg accgcacagc tactcgagga attcaaagac
    45121 gagatcaaac aatttcggat catggagacg acaacagcga gagtgatcga agaagtcaaa
    45181 gagcagcaca gtgagatcgg cattatttat atgaatgagc ataatcaagc tggtatcaga
    45241 agatatttac aacaaggaga gctaagtggc cgcagcattg gaaaattcaa aacgcatatt
    45301 tttttaaggc aaggacatcc attagctgaa cacgcagaga tcaccaaaga agaattgtta
    45361 tcttatcctc aagttcgttt tacacaggat ggaaataatt tcccgtattt ttatgaagac
    45421 cttatcgaga tccctgatca agaaacagtg atttatacga gtgatcgagg tactttgatg
    45481 aatatcgttc ttgaaactga tgcttacgct tcaggatctg gtattgtgat tggagggatt
    45541 cgcgagcact tgcggttaat ccctttggca gaaggcgaac taaatgaatt ttatatcatt
    45601 tattcggcga aacgtccgct cagtgaaatc gctcaaagat ttatcaaaga gcttactcgg
    45661 ttactggacc agcagagcta agaaaagcag atgagaacgc tgtttattga acaccgttga
    45721 tcaaaaaaga ggggttgtga cagaattttg tcacaactcc tctttttgta gcaaacaatt
    45781 tataactaat tgctgttgtg ggaaagtacg caaatatgat tctagaaaca ctcattgatt
    45841 acctgttttg tttcatagct gtaatttttt cttcttctgg tgtcacgata atcgtctttt
    45901 ggttttcata aataacataa ccaggcttgg cgccatttgg ttttcggata tgctttacct
    45961 gtacaagatc aaccggcact tgggcagagt atcggtattt tgaaaaatag gcagctaact
    46021 cggcagcttc tgtaattgtt tcatctgagg gcttgtcact tttaatgatg acgtgcgaac
    46081 cgggtatatt ttttgcatga agccaatagt cggttttttt agctgtcttc attgtcagct
    46141 ggtcattttg aagattgttt ttaccaacaa gaatgagcgt tccgtcagaa gaaaagtatt
    46201 gatcaggctg agatggtttc ttacgttttt gtttttttaa gttcttcttt ttcaggtatc
    46261 cttctgaagt caattcttct ttaattgctt cgatatccat tgggccggca atttccagtt
    46321 gagataagac agattcaaga tattggattt catctttggc ttcttggatt tgttcgccaa
    46381 tcagcttaac agcgttcttc agcttttggt atcgatggaa atatttctgt gcattttgat
    46441 ttggtgtcaa tgccggatct agtgctattt tgattggccg atcttcttca taataattag
    46501 gtaaaacaac ttcttttgcg ccgcgtggta cttgtgtcag aaaagtagta agtagttcgc
    46561 catttctacg gtaattctca gcgttttcgg attctttgag tgtttgttca cgttttttca
    46621 atttattttt atttcgtttt agttcatttt cgatttttcg aatcagttct ccgccttgtt
    46681 gttttgcccg atctttctct gctttttcgt gataatagct atctaataat tgactgagtg
    46741 ttggataagc tgttacagca gatgcctgtt cggacaatac ctgataagca atcggtgtga
    46801 aaaaatcttt attttccgtt tcgtaaaaag taggaatagg ctgatggctg atggctgaga
    46861 aaaattcgtc ccatacaacc atcttttcat taggacgttc cagtaatctt ttggtcagct
    46921 cttgagcgat atcgaaaccg attccctgaa actgacgttg gattgctttt ggatctagtt
    46981 cagtttggga aagccgctga aagatttttt ctttctcgga gctaaatggg ttcaagacct
    47041 cttgttttgg cggagcaaca tattctacac caggaagcaa agaacgataa gtgttttgag
    47101 agcttccaat gtgtttgatc gcatccagta tttttccagt ttctcgatta actaagacga
    47161 tcgtactatg acgtcccatt aattcaacga tcaatatgat attttgtaga tcacccaact
    47221 cgtttcgttt agcaaagtgg aaatggatca ctcgatcatt ttcgatttgt tcgatgtctt
    47281 ctaaaatagc gccatccaaa tattttcgaa gcatcatcac gaagttaggc ggattatcag
    47341 gattctgata atcgatttgg gtaatctgta cacgagcata acttgggtgc gcagataata
    47401 ataatcgatg gtttttgccg cgtgaacgaa tcaccagcac gatttcattt tcataaggct
    47461 gatggatttt cgagatccgg ccagatagta acgtttcacg caattcgttg accatcgcgt
    47521 gggtaaatac accatcaaag gacatggttc attcctcatt tcttttcata agtatattca
    47581 ttataacgaa aaaaagaaga aaaaccaatt tggccgaata gtaaagcaaa agtctagaaa
    47641 aatcttggac taattacata aaaaacagtg tttctatcgt tgaaatccaa atttttaggt
    47701 ataataaaaa ataggagaaa aagtagaaaa gaaggtgttt gttatttggg aagtagttaa
    47761 atcgagagta caagaaatga atgaacattt ctcagtgtca ttcgcagaaa atccaagtaa
    47821 gtattttcga cgtcttgttt ttctgctcat cttatcattg ctgttaacag ttgcaatgtt
    47881 tttattgccg gaaaaaatcc gagaagagca agtaaatagt ctcgtttatt cgtccatacc
    47941 aaccagcaaa ttgaaacctt ttgattacag caaagctgat cagaaaatca aacaaagccg
    48001 ggcgatatcg gtgatgttca gcaaaccgaa cgggaaaacc tatcaggaca tgcttgatgt
    48061 ttttaatgat cctgagctta tggaagaatt gaatcgaccg atcttttatt atccgatcgt
    48121 ttatgatgta catgaactgg aacaaaaata taacatacga acggatgaag tgacatttat
    48181 tttctttgat ggaggaaaag aagcaaatcg gataactgcg ggtaagggag gaataactga
    48241 ttttgataag gagttgatcc ctgaactgaa tcgacttccg ttagccaata tcaaacaatt
    48301 agaagaagaa ttggatagaa cgggagtaac ttcccaaaat tccgagattg ctaattgaga
    48361 cattggcgcg atgaaacggt gggtctatat agcgctattt ttaattatca gaacaagtga
    48421 tgtttgatct tcaaaataac aaataaaaaa ttaaaaaata tagttgacga aattcaaaaa
    48481 ttcgattaga cttaaatcaa ttcttaagga aagggtgacc tgtaatgaac ttatcaaaac
    48541 gtatttcagc agaaaacaaa aaaaattggc gcagctggcg tagataagtt gtattaatgg
    48601 tgagactttc ccatagatac aactttttag agtgcatttc taaagcttgt atctatgcta
    48661 gacatgaaca ttgactgccg catagattag aatctatgcg gttttttgtg taaagacaat
    48721 gaccgctttg gccattgtct ttttttgtag actggatact tgcctgatta taataaataa
    48781 aaagattgac tttgcaggag gaaaaaaatg aaaaacaaac gattaataac agttgtagta
    48841 attattttag tttatttagc aggtgcattt atttatggaa aagcctcagg cgaaaaagaa
    48901 agtacttcga cgaaccagac aaaaaaaaca acagttgttg gggtattgca atacgtgagc
    48961 catccggcat tagatgagat ttatcgagga atcaaagatg gtctgaaaga agaaggatta
    49021 aaagaaggag aaaatcttga gatcaaattt caaaatggac aagccgatca gagcaagcta
    49081 gccacaatga gtcaacagct agtacaatct gatccagatg ccttgattgg aatcgcaaca
    49141 cctgccgctc aatcattagc aaacacgact tcatcgatcc cagttgtgtt aggtgctgta
    49201 acggatcctg tgggggctgg attagtcgct tctttagaga aacctggtgg taatgtaaca
    49261 ggtgtttctg atcagccgcc tgttacttca caaatcaagc ttgcttctga tttgttgcca
    49321 aatgcaaaaa aagtcggaat cttgtatgct tcttcagagg ataattcaaa ataccaagta
    49381 gcacaagcag aagaagctgc aaaaaaagaa gggttagaat cagtaaaata tgcggtgcct
    49441 tccactaatg agattgcaca aacggttcaa gtgatgagcc gacaagtcga ttttatctat
    49501 gttccattag ataataccat tgccaatgcg atgcaaacag tggtaaaaga agcaaacaaa
    49561 gcaaatatcc ccgtcattcc atctgtggat acaatggtgg aacaaggtgg actagcaaca
    49621 atcgggatca atcaatatca attagggctt caaagcggta agatggcggc agaacttgcg
    49681 agtggaaaag aaaaaccgga aacgacgcct gtttatacat ttgatcaagg ggatacagtg
    49741 atcaatcaat ctcaagctga tcgcttagga atcattgttc cccaatcgat gaaggaaaaa
    49801 gccaaaatca ttacagatga ctcgcagcaa gaaacatcta aggaggatga caaatgatcg
    49861 tatcagctat ttcacaaggc atgctttggg caatattagg attagggatt ttcatgactt
    49921 atcggatctt agactttcct gatatgacga cagaagggtc cttcccatta ggtgctgctg
    49981 tctgtgtgac agctattact catggggtag cgccgattgt agctacatta ttaggcgtag
    50041 gtgctggcat gatagcagga ctcgttacgg ggttacttta tacaaaagga aagataccgg
    50101 ttattttagc agggatttta gtgatgtcag gattgaactc agttattttg tttgtgatgc
    50161 gaacaccaaa tctttcttta ttgaatcatc cgattctaca agacagcttc catcgctttg
    50221 ggttacctga ttactttgac acagtccttc ttggcttcat ctctttgggc atcttgattg
    50281 ctgtactgct attcttcttc aatacagatt tgggtcaagg ctatattgcg acaggagaca
    50341 acgaaacgat ggctcggtcg ttagggataa aaaccgatcg tatgaaaatt ttaggtttaa
    50401 ctttgtcgaa cggtgtcatt gcattatccg gtgcgctgat tgcccagaac gacggatatg
    50461 cagatgtaaa taaagggatt ggcgtaatcg tcatcggtct tgcttccatc atcatcggtg
    50521 aagtgatctt ccaagaattg acgctagcag aaagattgat tgctattgtt gtcggcagta
    50581 tcatttatca gctattgatt ttagtagtaa tcaaactagg gtttgacacg acttatctga
    50641 agttgttctc cgctatcatc ttagctattt gtctgatgat cccgcaattg aagaaagcac
    50701 tgaacttaaa aacgggtttt gagaaggagg catagtaatg actgatatat tgacaatcaa
    50761 aaatggcaga aaagtcgtaa acaatggaat gaatgaagag aaagtactat tggatgaaat
    50821 taaccttaca atcagagaag gggacttcat cactgtcctt ggcgggaatg gtgctggaaa
    50881 aagcacactg ttcaatacga tcgctggtac gcttcaactc agtcaaggat cgatctcttt
    50941 taaagatcag ctgatcacaa aagattcaga agaaaaaaga gcacgattcc tttctcgagt
    51001 tttccaagac cccaagatgg gaacggctcc tcggatgaca gtagcagaaa atttgctact
    51061 tgcacaaaaa agaggtcaaa aacggaaatt ccgtttacgt aacttgaaaa atcaaaaaga
    51121 agattttttc agactatgtc aagaagtcgg taatggccta gagcaacact tggatactcc
    51181 agcgggtgaa ttatctggtg gtcaacgcca agcattaagc ttgctgatgg cgacgatcac
    51241 agctcctgag ttactattat tagatgaaca tactgcagct ttagatccta aaacagctaa
    51301 agcattaatg cgattaacaa atcagcggat caatgaacaa aaattgactt gtctcatgat
    51361 cacgcatcga atggaagacg ccttgaaata cggaaatcgt ctgatcgtac tccaaaaagg
    51421 gaaaatcgtt caagatattt ctgaaaaaga aaagcaacat ttgacaatgg gcgacctttt
    51481 gcagttcttt gaagaagtag tggattgatt tcgacagaaa aattcctttc agtagaagga
    51541 cttgaaaact cattgacatc ttcctttgat tcatcctata cttaaaacaa taaacaatta
    51601 aacatatttg ggtgttttgt aggatcacgt agtcaatgat tttaacaatt aaatagaata
    51661 ttctttgctc tgacaagtaa acgatgagaa aagaatttgc tactttgcca cctagacgtt
    51721 tcgtactttt tcgtatcaaa cgctaagtgg ctttttttat tgaagtaaga acaaaggagg
    51781 aataagatga tttctggaca aaccaaatta gctgggctct ttgctgatcc ggcttctcac
    51841 agtttatccc cattgatgca caatactgct tttgaagcaa acaacatcga tgcggtgtat
    51901 ttagctttcc aagtaaatcc aatgaatttg aagcaagcag tcgaaagtat tcgaactttt
    51961 gatatgttag gtgtaaatct ttcgatgccg aataaaacag cggttattcc ttatctggat
    52021 gaggtaagcc aggaagcgca attgatcgga gcagtgaata cgatcgtgca cgaaaagggt
    52081 cgtttgattg gctataatac tgatggtgcg ggcttcatgc aatccgtgca agaagctggg
    52141 atttcgatca aaaagaaaaa aatgactcta ctgggagctg gaggtgcagc aaaggcagtc
    52201 actgttcaag cagcgttaga cggcgctgag gaaatcgtag tttataaacg aaacaaccaa
    52261 acattcgctc aagtaaaaga aacattcgaa caactcagct atcgaacttc ttgtaagata
    52321 aaagttcgtg actttgccga tacgcatcaa ttaagaaaag acttgaaaga aagctgtctt
    52381 ctagtcaatg caacagatat cgggatggga aagaaaatca atcagtcacc gctcttagat
    52441 ataagcatga tgcatgagaa tctagcggtt tttgatttga tttatgcacc tagagaaaca
    52501 cgtttattaa aagaagcaaa aaaagtagga gcaaaaggat acaatggact tggcatgttg
    52561 atctaccaag gagcaatcgc gtttgaatta tggacaaagg aaaagatgcc gatccatgtg
    52621 attgaaaagc tgtttgatta aaaaaggata atagataaag atcttttatt ctcgcataaa
    52681 cggtctcaag aaaagtaatc ctttatgtat cgaagcattt atttcgttat tttttattaa
    52741 attatcaaaa aatgataggc ttttgtcgat tggttatcgt atcctttatt tatcagtaag
    52801 aaacgaggag gaaccacaat gagtcggatg gatcgctata aggacatcca taagaaggcg
    52861 aaacctctga agcgggatac ggggagtatt tttgctagaa gagaacgaaa acgaacgcgt
    52921 atggaaaatg aggaagatgc tacccgtatt tatgaaagag agcagcattc atttgaacat
    52981 ttgaaccaat acgagcaaca gatatacaga gatgcaccaa gagcagaaga acaacaaaaa
    53041 aataaaaaat ttttcaatcg gcaaaagaag aacaaaccgt taaaacctcg aagaaagcga
    53101 tcgtggaaaa aaatcattct atcgattttg cttgttttga tcctttattc aggtatctca
    53161 ttttttattg gtaaatatgt agctgaacat gacacaagct tagaggcagc gacttcagaa
    53221 acctttcatg ggcaaaaagc gacgaatggt gcgcataata ttttgatcct tggaagtgat
    53281 acacgcggag aagatgccgg gcgagccgat acgatcatgg tcttacagtt ggatggtcct
    53341 tcccataagc cgaaactgat ttcttttatg cgtgacagct tcgttacgat cccaggggta
    53401 ggacaaaata agatcaattc agcttatgca tacggaggag ccgatctagt gcgtcaaact
    53461 ttagtagaaa attttggaat cgattgtcaa tactatgcga aagtcgattt caaatcgttt
    53521 gaaaaagtga tcgatgcctt attcatgaac ggagtgaaga tcgatgcaga aaaagatctg
    53581 aatctggatg gtgtagatat taaaaaaggg ggccagaaga tggatggaca tgttcttttg
    53641 cagtacgcac gtttccgaat ggatgaacaa ggagactttg gccgtgtcag acgccaacag
    53701 caagtaatga acgctatttt cagccaattg aagaatccat tgaatctgat ccgtgcacct
    53761 tatgcagctg gtaaagcttt aggatataca tccacagatg tcactgcttg gttcttgacg
    53821 aaaaacctct tttcgattgc acgaggagct ggtggcattg atcgaataag tgtgccagta
    53881 gacggttcgt ggaattatgg gcaaagtgat tatgctggca gtattcttga aattgataat
    53941 caaatgaatc aatctgctat tacagatttt ttgaataaat gatcataaaa aagatcaaga
    54001 agaagctgcg caaggctttt gtcatgaatc aatcaaacga ttcactcgta aaaaacgctt
    54061 tcttatggta gatttaacca agagaggagc tgtttacatt ggatatctat ctgaacttca
    54121 aaaatgagtc gcgtgaagcc atcgcttttt atgaaaaagt ttttcagact gaagcatcag
    54181 gtatcaccac atacggtgaa atgcctggaa tagaacaaat gaacttgcca gaagaagcaa
    54241 aaaatctaat cacgaatgca cggctgaaca tttatgatac attagttatg tttgcagata
    54301 cgccagaagg aattggtcct gaattagttg tgggaaataa tgtttcttta gtcatccaga
    54361 caagaaatga agaagaaacg aagcgcctat ttgaaagctt agctgagggt ggtaagattg
    54421 agatgccact ggatgctgtt ccgtgggctc agttgtatgg gatggtaact gatcgatttg
    54481 gcatcaactg gcagattaac caagagtgac agctaaagat gaatattttc tggaaacatc
    54541 aagcagcaaa cggatcatcg tttgtttgct tgatgttttt gtgtctattt cgactatacg
    54601 gtatcttttt tttattgcca gatgcgaaaa tatgttccat aatagagaag tccgcaaaaa
    54661 attaagtaac ggaggtcaga agatgaagac ggtgatacta gctgaaaaac cttcacaagc
    54721 aaaagcctat gccgaaacct tccaacagca aaagcggcat gaagggtatt atgaaatcag
    54781 cgatccattg tttgctggtg aagtaaccat cacttatggt tttggacatt tggtagatat
    54841 ggttgctcca ggagcttatg aagagcgttg ggcaaaatgg tctttagaaa atttgcctat
    54901 tttcccagaa accttccgtt acgaagttcc aatggacaaa cgtgcacaat tttcgatcgt
    54961 aaaacgagaa ttgcagtcag ccgataccat cattattgca acagatggtg atcgagaagg
    55021 tgaagccatc gcgtggtcga ttattcgaca agcaaacgca ttttctaagg aaaagaacta
    55081 tttacgttta tggatcaatt ctcttgaaaa agaagcaatc tatgaaggtt ttaagaatct
    55141 ccaacctgga aagaactatt ttccaaaata taaagaagcg caagcaaggc agaacgctga
    55201 ttggctgatt ggaatgaatg gaagtccatt atatagcttg ctacttcaac gaaaagggat
    55261 tgatggcagt ttttctcttg gtcgtgtaca aacaccgaca ctctatatga tttatcagct
    55321 gcaagaagaa atcaaacact tcaaaaaaga aacgtacttt gaaggagaag gtttaattac
    55381 gacaaacaaa gggcagtttt ctggaaaaat cgtaccaaaa aaagcattta aaacccaaga
    55441 agagttaacg aaggaaatag aaaaacttgg agcgcattta ggtaagcaaa acggacggat
    55501 tcttgaagtt acgaaaaagg aaaagaggtt gcatagtcca cgtttatttt cgctatctag
    55561 tttgcagaca aagatgaatc agctaatgaa agcaagtgcc aaagctacac ttgatgctgc
    55621 tcaaggattg tacgaaagca agtttctaag ctatccaaga acggattcct tttacattac
    55681 agaaaatgag catcagtatc tggttaaaca tctgcaaaat tataaaaaat ttttaggaat
    55741 agaagaagta cagacaactg agatcaaagc aaagaaacga tatgtcgatg cgaaaaaagt
    55801 tcaagaacat catgcaatta ttccgacaaa gacgattccg actcctgcac gctttgcgaa
    55861 gctttccaaa ttacagcaag caatctattt gcaagttttg cgcactactg tggctatgtt
    55921 tgctgcagat tatatctacg aagagacgac cgtaatgacg ggcgtacagc aattaaagct
    55981 aaaaagcatc ggaaagatcc cattacagca aggttggcag gaaatcttac gcatcaagtc
    56041 aaaaaagaaa gaagctcaga ctcttcctcc tatcgtagaa aatgaagaag cagaagtaga
    56101 actgaaaagt atggagaaag aaacacaacc tccaaaaccc tataccgaag gaacgttgat
    56161 cacagcaatg aaaactgcgg gaaaaacgct ggataatgat gaagcgcaag aaattctcaa
    56221 agaagtagaa ggaataggga cagaagctac acgagccaat atcattgaaa atcttaagca
    56281 gaagcattac atcgaagtca ataaaaacga aataactgtt acgccaaaag gaatcactct
    56341 ttgtaaggca gtagccaatg aaccattact gacgagcgca gaaatgactg cgcgctggga
    56401 agggtacttg agaaaaattg gtaaacaaga ggggacacca tctgtttttt tagagaatat
    56461 caaaaaattc atcctacatt tattggcaga agttcctaat caaatcgaca aggtagactt
    56521 ttcagatgag attagcggga cacgtcagat aaaagcgatg gagaagaaaa acgatcaatt
    56581 aggaagatgt ccaaaatgta aaaagggaat agtcatgctt tatcctaaaa tcgctacatg
    56641 cttgaatccg gaatgcgact tcaaattgtg gccaacagta gctaaaaaga agctgactaa
    56701 aacgaatctc agagatttgc tttcaaaagg aaagacaagt aaagttgtca aaggttttac
    56761 tggtaaaaaa gggaaattcg atgcagtttt agtattaaaa gaagatatga caatcggttt
    56821 ttcttttcca tggatcgaaa acagtggaac aaaagcagtt gatggaaaca aagaaacatc
    56881 aagaaaaaat aatgaaaacg aagtagagta aatgaaaaca atgaaatagc ggaatattta
    56941 ttccgaaaag tgagaatata aataccaata aaactaaaaa atatcagtga atcaagcaaa
    57001 aacgttgggg taggctgatt ttatatagat agcaaggagt ttttttattt gaaaaaagtg
    57061 cattcatttt taaattatct tatgggagca atcacgattg tggctgtgta ccaagcattt
    57121 ctaaagtatc ctgattacgg gacgaagttg ttgtcattga cgcacaatca aacagcatat
    57181 tcaccaacgt tgattttatc gactttgact gcaggagcta aaagcgctac ttattttttt
    57241 cataaaacga caagcatgct aaagcgaaag aaacagcgaa aacaattgtt ggtggtggta
    57301 gcggctatga tcattattta ttttctacca gttattacac aagtatttca tcaatatttt
    57361 ggttaagaat acgagagttt gtgacaaaag tcatgtcaca aacttttttc tttgtcattt
    57421 tttcgtaaga aaaagcaaaa taaaagtata tacattgatt aaaagtatat acttggatat
    57481 aatgtactta ctatagaatg agaatggtat agagggtggc gaaatatgaa aaaaatgaaa
    57541 aagtataaaa ttagaaaatc tggcaatagc gatgtaacaa ctatcccacc agaagtaaaa
    57601 gaattcatgg gtgtgcagac aggtgacgca atcagttatg tttttcaatc tgatggttct
    57661 gtacgaatga tcaaagcaca agaagaacct gatattgatt cattagttga ttcgatcatg
    57721 aatcaatatg aagacgcgtt aaaagatttg gttgatttat gaggtatctt tcgactaaag
    57781 aaattatcaa aatcaacgcg aaagttattt taccgtcact cgccaggcga aatgatcggt
    57841 gtaaaagatg caaatgcatt agatatggcc gtcaaacagc cttcacaagc agtattcaat
    57901 caagaactct atcctgaaat ctatgaaaaa gcggcgattt tagcaattaa tttagctaaa
    57961 aaacatcctt ttcataatgg caataaacga actgctcttg ttgccatgtt gttgtttctt
    58021 caattgaata attgtccagt tgctttttct cgtcaagaag ctgttgattt tatcataatg
    58081 attaccacta gttcattgga tttcgattca ctaaagtcca agataaccag ttatttacga
    58141 caaaccgcaa taaaatgaac gaattaaaaa ctttatttct caattagatc agcatgtcat
    58201 taaggaatat gctgattttt ttatgtttaa tcatacaaaa tagttttttc ataaaaatat
    58261 ggaaaatatg gattaatttt gaaataattg atttaaaagg aatacaaaag agtgaatagt
    58321 aggaaatagt ggtttagaac tagtgggctg attttttata tattttagtt tacataatat
    58381 atattataca aagtagattt aaaaaatgat aaacctctct cgaacggttt tttatcaaaa
    58441 atcgtcattt ttccatcaaa atctgcttat gcaaaattat aaaaaaattt tgcagttttt
    58501 cttacttttt ttgtcgttta attgaatgat aaaaaccagt ttctttattc agttaatcaa
    58561 atatgaacga attagatatg aatcattgta tttgccgttg cggaaggatt ttttaattaa
    58621 ccacagataa acattgataa cgattcgctt attgtaatca acagattaaa tttcatatgt
    58681 tcatatgtac ggatacattt tcggaccgat taattttaac cattctgttt atttgcttac
    58741 ctattagata tcaataaaaa actgcttaac agctatttca gctgttaagc agttttagga
    58801 tttttagttc atattcattg tttcttataa tacagtgttc aatacttctc ttaaagcact
    58861 tgttgatttg ctgaacattg ctttttcttc ttcgttgatt gataattcaa caacttcacg
    58921 aacaccattt tcgtcaacga ttgatggcac acctgtaaag atatcttttt cgtcgtattc
    58981 accagttaaa taagcagata caggcaatac agcttgttcg ttattcaaga tagcttttac
    59041 gatacgtgca gtactcatac caataccata gtaagttgct tttttacgat caatgatctc
    59101 ataagcagca ttacggactt tatcagcaat cacatctaat tcatcttggg caatacgatg
    59161 gtctttttct acaatttcaa acactggttt accaccgaca gttgtatgtg accatgcagc
    59221 aacttctgaa tcaccatgtt cacctaagat atagccgtgg acgctgcgtg ggtcaacttt
    59281 taatttcaat gcgatttctt tacggaaacg agttgtatcc aatgttgttc cagtaccgat
    59341 aacacgtgat gttggcagac cagattcgtt ccaagcgata tatgtcaaaa tatctactgg
    59401 gtttgaagca acaacgataa taccgtcgaa tcctgatccc atgatttctt ttacgatttg
    59461 gcgcatgatt gacgcatttg ttttaactaa atctaaacga gattgaccag gtttttggtt
    59521 gataccagct gtgataacaa cgatatcagc atctttacat tcttcatagc cacctgacca
    59581 tacagccaca ttttcatcgc cccaagccat accatctaaa aggtccaatg cttccccttc
    59641 tgctttttct tgattcacat cgatcaatac taattcatta gagattcctt ggttgatcat
    59701 tgcataagcg atacttgttc caacaaaacc tgtaccgacg attactactt tacgacttgt
    59761 ttttttcatg aataaacagc tccttttcat aactatttgt tactttcatg aaaagtatag
    59821 tcttgtttat tcattttatc aacatgttaa ttataatagt tgttattata atttttgatg
    59881 gaaacgaatt cctgaatacg cataacagat aaatgacaaa tgtttacacc tatatcccct
    59941 gataatacaa ccaaaagttt agaactgaaa ataaatccaa aaaaattcgc tgcaacgata
    60001 taataagaca gcaatcgcac ctaaaacaat tttccttcat atgctttagt gaaagatttt
    60061 cttcttaatg tttatttctc cattcattgg gagtacatgt tgaatacttc ttgaataatt
    60121 tgaataaaga agtcgtttgt ttatatccga tacgattagc gatttcttcc aacgaaaaac
    60181 tcgtttcttg aatcagttcc aacgcaaagt cgaatttttt ctttagaacc agttcttgaa
    60241 aggaagcatc aaaatacatt ttcaatttat tactaagata gaccggattg tagccaaaat
    60301 gagctgctgt ttcttttaac gtacaagaag taaaatgctt atcgatataa tctaatactc
    60361 taagcatctc attttctgcg catccatctg ctgatgaaaa gctttgttgt tctaataaat
    60421 gagtcaattc gatcagtaat agtgatgtat agagatttaa cgaacggatc ttatgactgt
    60481 atgtatcaaa ataaatcaac agcatatttt caatcaaatg cgtcaaacga cttgtttttc
    60541 cgccgcgaaa atgaatgaat tgtgtatgtt cccctttttc ttttgatgca tttatcaaaa
    60601 aagaagaaag tagattattt gtgcttgcca aatgattcaa tatctctgta gataaggttt
    60661 cttcttttaa taagatgttg attaaaatat cctcttgccc tgtgtattcg attctttgag
    60721 tagcttcttt atcaatgatc accacgtcac tttcttccat ctctatcctt tctccattaa
    60781 taatttgtaa acatgtaccg ctatacatat aattgatttc aacaaaatca tgtgtatgct
    60841 cgggaacttc cgcatatcga cggtgtttac tgatatgaat atttccctgt tgaaatagat
    60901 cccctcggtg gatttttggc ggtgtctgaa gatggtaagc taagtttaaa tcattgatat
    60961 tcattccttg ttcacgctgc agagtttcga ttgattcttc gttacgcaaa aaaaatgtct
    61021 aattcagcta gttccaattg actccctcct ttttgtaagc ggtttctttc gcttattagt
    61081 tcacgctgta ctgctattat atgcaaagct atttttggtt tcataaagac tttctatggt
    61141 tgggacatga acttcctgtg attccgctat tgagagaata accacttcat actatatttt
    61201 tgataagcgc ttacaaaaat gaaaggaaca tgcttatgaa taaaaagatg atgaaatttt
    61261 ctctgctgtc agtctctctt attttgactt ctgctggtgc agtcacgtct gcaattccca
    61321 gtatgtcagc tacttatgcc acgcgttctt tatctgctgt tgaattatta acgactgctc
    61381 cctcttttat ggtcactatt tttgttttga ttagtagttt tattgctagg aaaatcggac
    61441 aaaaacaaac tgtgatcatc ggattagtga ttgcatcgat ttgtggtatc ctccccctct
    61501 tctcacaaag ttacagtatt gtcttagctt caagagctgg actaggtatt ggctttggat
    61561 tgatcaattc tttggcagtc agcatgattg ctgcctttta tcacggagat gaacgagcct
    61621 ctatgattgg ttttcaaagt gcatttcaag gatttggtgc agctttaatg acatttgttg
    61681 caggacagct agtacagttc ggttggcaat ataccttttt agtctacgcc atcagcttac
    61741 ctattcttgt cttgtttgtt ttgtttgttc ctacacctga aacaactgaa cttcaatcgc
    61801 atggcacagc cccaacaaga caagtaatca aaacgaatcc taaaatgatt agttatggta
    61861 tttttctctt gctggtcatc gtggtatata atgctgtatc gattaaatta gccacagtcc
    61921 tgacgactta ttctctagga aacgaaacta atgcagcgaa tatcttaaca atcatgcaat
    61981 tggcaagtat ggctgccgga gtttgttttg gctggcttca gacaaaagca catcgctata
    62041 tgcttacact ttctttacta ctgatgggaa tcggctttgt attgattgcc actgtgataa
    62101 acctgtatgt gattgggttt ggtgcgatcc taacaggaat ttctttttcg ttattcattc
    62161 cttacttatt caaccaagta agtatccaag cgcccaagta cgcggagagt ttcaatactt
    62221 caatcttatt ggttggcgct aatttaggta ctttcattgc accatatggt ttgctctttc
    62281 tctcttttgc ttctcttggg agtaaaacac ttgctgtttt cgtcaatggc agtatcttgc
    62341 tgttgattag cgcgcttatt agccttctag tagtacacag gacgaataga aagacagtga
    62401 taagagtaga tgaagaaata aaagaacaat tgacaacaaa ataaatttga tggaggtcgt
    62461 gtaaaatgac aaatgaaaaa cataaagata gatggctttg gtatcctgga gactttgaga
    62521 tccgccatgg actgctacaa aatttccaac gggaagaacg aggttttgac tggccagcgt
    62581 actggtacat ggatgattgc catcggaacg tcaagtttaa gagatattac tttcttgatc
    62641 aaccttccat gtttaaagtg acgatccaag gagttgggta tgtagaaatt aatggacaaa
    62701 aacatccatg tggaaaatgg ctgacttgtc cagctggtaa agcaaaaatt cgtatctttg
    62761 taggacatac atcagggcta ccagcgatgt ttatcgaggg agacgaagta aaatcagata
    62821 ttggctggac agcaagtaat tttattgaag aatatccagc tggctggagt ccgctttatg
    62881 tcgatatcgc aaaagatcca aatcaaatct attatcaaaa agaatgcgtc catccagtca
    62941 ctgaaacgga gattggcgga ggaatcttat tcgattttgg gcgagcagtg aatggctgtg
    63001 tagaactaat atctctggat gaccatatcg aatctatcac tctatgttat ggagagtccg
    63061 atgtagaagc tatggatatc gattattgct actataagca aataggaatg acaagaaaaa
    63121 tgaaagctcg taaacgcgct tttcgctatt tgtttatacc agaggtttct actggaatgg
    63181 ttcaacttca agtttttcat gaatttttat ctctttcgaa acaagctgct ttttcaagcg
    63241 attcttcttt actgaatcag atctggtcag tatcagaaga agccttcaag ttatgtagtg
    63301 atttgttttt tatcgacggt atcaaacgag atcgctggat ttggtctgga gatgcgtatc
    63361 aatcattcat gatcaatcaa tatctttttt ttgacgagga aatcaataaa cgaacgatat
    63421 tagcattaag aggacaaaat gaaatcaagc agcatatgaa tactatcgtt gactattcga
    63481 tcttgtggtt gattggtatc gaaaaccact atatgatgac gaaagactat gaatttttac
    63541 gcatcgtcta ccctaagatg caatcattaa tgagatactt gatggagcaa acgaatgaat
    63601 tagggtttat ttatgggaga gcaaaagatt ggatatttat tgattggtct gaaatggata
    63661 aagaaggaac gcttgctgca gaacaagtct tattactgaa agcctatcat tccatgatca
    63721 cttgcggaga tatcttagct gaaacatatg gagagaacga aaattatcat actcatctct
    63781 atcaagaaaa atatcaacta ttgaaacaaa acctatttga ctacttttgg gatgaagaac
    63841 ttggcgcttt tatcgattgc tatgaatctg ggagaagaaa tgtgacgcgt catgcgaata
    63901 ttttcgctgt tttattcgat tttgctaaca aagaccaaca gcaatcgatc ttaaagaatg
    63961 tcttattgaa tgacactatc acacagatta ctactccata tttcaaattc tatgaacaag
    64021 atgctttatg caaactcgga cagacgaata tcgtctacca aacgattctt gattattggg
    64081 gagggatgtt atctcatgat gcggtaactt tctgggaaga atacgaccct actcaaacag
    64141 gaaatgaaaa gtacagtatg tatggagatc cttatggaaa aagcttatgc catgcatggg
    64201 gagcaagccc aatctatctt ttaggacgct attttatcgg tttgtatcca acaaagccag
    64261 gttatgaaga atttatgata caacctaatc tagattcatt tgaaacactg aattgtacgc
    64321 tacctatcaa agatggaaag atttcgcttg aaaaaacaaa agataagatc gtgattactt
    64381 ctgatagaac aggcggaaca gtgaaaatga atggtaaaag ttatcctctt ctagcaaaac
    64441 agccacttgt cttaacaagc tattcaaaaa taaatgcata aaacaaaaaa ctgcttgcga
    64501 catatcagaa gactttaaat cttcttctga tattgtccaa gcaattttta ttttgaagtt
    64561 tgcttaattc tgttctttag aaacaatgtt tgttcttttt ccggcaaaaa gaaagctaga
    64621 taatacgaca agtaaaaaga aagcgatgat tccaactgtc aaggctattt gaccgtattc
    64681 tcctagtttc ccaagtacaa gtcctggtac tagataatca gtatcggcaa atgtagaaga
    64741 agcgatttta agatctccta atactggaag gataaataat ggcagccaac taatcaataa
    64801 gctattgaaa gcagaaccta ataccgcccc tcttctaccg ccagtcgagt tgccgaagac
    64861 accagaagca gctccgcaga agaaatgtcc tactacccca ggaatgataa ctgtagtttg
    64921 caagcctatc atagcaaaca tggatagtgt tcctacaaag aagctaacaa aaaagccaat
    64981 taatacagca ttaggtgcat atggaaaaac gataggaaca tctaatgctg gtttagaatc
    65041 gggtacgagt tttttagcaa tcccttggaa tgctggaacg atttctgcca acaccattcg
    65101 aaccccttga aggacgataa caaacccagc tgtgaatgtt ccagcttgga tcagtgcaaa
    65161 gattacagcg ttgtctccat tgcttagttc tctttcaaca aatccaggac cagctaacaa
    65221 agcaagtgcg acatatacga tcgacatcaa gagcatgatc gatacagtag aatctcgcaa
    65281 aaagctgaaa cttttaggaa tctttatgtc ctctgtagaa cggtctttgt ttccaaaaaa
    65341 ctttccgatc catccactag aagcataacc gatatttccg gtatgcccta acgcaacttg
    65401 attgtttcca gtgatgttct tcataaacgg ttgacaaaga gcaggcgtaa tagttaatag
    65461 tgttccttcg aagaccccgc ctaataagat catccacaaa tttgcagtaa accccgcgct
    65521 tactaaaatg actgctgtta gacaagaaac ataaagcatt gcttgacctg taagaaaaat
    65581 gaatttatat cttgtgaatc tagcaagtaa aatattcacg atcatcccta ctagcatgat
    65641 caaagcagta ggtgtaccgt attgttgcaa agcaatcgcc actactgctt cattgctagg
    65701 aactactcct tgagtatgca gagctgtttg gaacatcgaa gcaaaagggg ttagtgaatt
    65761 actgattaaa ccagcaccgc cgatcagtac taggaatccg acaaatgttt tgatagttcc
    65821 ttggatcact tctgaaaatt tcttcttctg aagaacgaga ccaagcagtg caatcaaaga
    65881 aacgaggatg gagggctgac tgacgattga cacaaacaaa ttcaacaatt tatccattga
    65941 tagttcctcc cttgaatcat ttttattctt ttgacaagat cttcgttact ttttctttta
    66001 cttcttcgct gtcaatgatc gattgcaaag gtacgagctt ttcatcaggt atagaagtta
    66061 gcgtatcttt caaagaatgc tcaatgaaga aataatcagc catatcgcta gatacacttc
    66121 caacatccgt atgacttact tcaaactcgt ccacatctgc tccaagatct gcaagtgctt
    66181 gtttgatgtt catctctacc ataaaacttg ttcctaatcc actttgacat actgcaaaaa
    66241 ttttcatatc attcgtctcc ttttcttatg atcgctaata tttcttcttt tgttgatgcg
    66301 tgtaataaat cttgaagatt ttgtttatta gaaagtagct ttgttaaatt tgccaaagcc
    66361 cgaagatgtg cctcattatc gatagcagct aaacagatga acaaactaat gggatgggct
    66421 ggattatcaa gcagatccac aggttgttga agtttcagca aagacatccc tacttcgttt
    66481 acgccatctt ctggacgagc atgaggtaat gcgatgtgat cgccaatatg gataaacgca
    66541 ccatactgct ccacgcgctc gatcatagct ttgatataac tttcttctat tttattttct
    66601 gataatagcg gctgtgcggc aaatgtgatt gcttcttgcc agttttttgg ttgatccgat
    66661 aattggatca tttcttctgt taataattca gatagcatag gacgttgatc ctccttcttt
    66721 tctaaaagtt tgttcatttt acgatttaat acttgataga gcttttcttc gtctacgcct
    66781 tcttttaatt cgatataagg cagtagcgcc gacaacaatt cttgggcaga aggcattgaa
    66841 aatcctggta tcagccaatc tctttgtact tgattgatca gctgattttt ttccaagtca
    66901 gtcatgattg gatgcagaac atagagagac tttttcttat cagtaagtgt gagaggtaca
    66961 gtagaaaaaa taatatcgta agaagtttcg tcaacctcgt gtaagcggtc agctgaatta
    67021 gtctctgtaa aaaagatcat cgggaataat tgctgaagtt cactttttaa gatcaatgaa
    67081 gagctaatgc cacttggaca gacgatcacg gctcttattt ttctatttct ttcttctgcg
    67141 tccgcttttc tgatctctcc gccaaatagt atagtgaaaa aaccaatctc ttcttcaggg
    67201 atgctcttcc ctattcgtct ttctaacgga agtaatgctt ttcttgtcat ttcgtagatg
    67261 gaagcatatt gatgcttaat ttgatcgatc atcacattag gtaaataaaa agaataggaa
    67321 atacgaaaat aggcagggac caagtgataa aagacattca tcaataattc acgaaacgaa
    67381 gcaaattcta cggccatcag gaattccatg cgatggatga cttctgaaga acattccagc
    67441 aaaaaatcaa gtacaggctc ctggacatct ccttcaacga tcgatgctaa gcaaagagag
    67501 aaaaatataa tctccgaatt ttgatgttcg gaatagccaa ggccagtcaa tacttgtcga
    67561 ctaatgtcag tgactgcaag agaagccaac agttcagcat cttttaccag ttccatggat
    67621 gtttttccaa ttcgaatggt tgtcaaactc aaataataag ctaattcatc cattcgattt
    67681 ggtgcgaatc gaagatctga tagtgaaatc gttttatcta gcaaatctct aactttggcg
    67741 taataatcaa tggaaagggt tgcggttaaa tacgtgagcc caaatcttcc agcaagtgac
    67801 tgcatcaaac gagcagtgcg attttttgct tctcttctta atattgcttc tgaccctagc
    67861 agcctaaaac cagttttcct agtatacgac agctgacaat cttccacttc taattcattt
    67921 cttatctttt tgatatctga caggactgtc cctttagaaa cctgaagaaa atcttgaaaa
    67981 tgaaaaacag aaacagacgt tgcagtcgaa taaaccatca aataaagaag atctcttcgc
    68041 tcttgttcgg tatacacagc ttcaaatcga gtaatatcca aaaatttttc tgcccagtcg
    68101 attgctcgga atttctttat acggatacgg gtatcatcca catattcggc aaaaggagtt
    68161 aattgtttga tcgcctcgct tgtatttact tcgatgatct ctgctgcttt ttctagactg
    68221 atttctcttg gtgttttcag gagataacta attttgtagt tcacagcgct gttcacctcc
    68281 tacttatatt ctagtatggt agcgctttta aatcgagggg tgtttggtac aacttacagt
    68341 tggatttttt ttacgactgt accgaacgat ttctatcgaa tggatacaga aaaaaagcag
    68401 gtgaccaaat gtctcctgct tttatgaatt gatttcgtcc gatcaatgat gatcatgttt
    68461 attttttgag gtcagttctt caaatttttc tttgacatct tcaaccgctt tttcgatatc
    68521 tttttcaaag tgattgggct cattaggctt tgtttcctct tctacagaat ttgaaccaga
    68581 taaagctgtt tctttatttt ctgtttcacc agagtttgtg ccagctaatg attcttcttt
    68641 gtcttctgtt tcaccagaat tagttcctgc taaagccact tcttcttctg ttttaggggc
    68701 cattgaacct cttaatcgtt tgtgtttttc accgtcataa tttgtcatgt tggttcctcc
    68761 tagtagttct atactttttc atcgtacaat aagacagttt atgcgtcaaa aaacaaaccc
    68821 gattcttaca aatatgtcat atttttcctt ctgattcttg aatgcttttg attccttctt
    68881 ccaaaatttt catttgtaag attgtttctt catctttgat gactttttct gcgccattaa
    68941 ctaatgtctc gtaaatccct tcgtagacac ggctgtaatc accaacctcg gaaattactt
    69001 tttcttcatg ataactccct tgttcatcta tataggtcaa tacaccataa tgttcgggca
    69061 aatcgatacc aaagtcttca tgatcaggca tgtaaaacat tttcagatgt tcttcttgtc
    69121 gatcttttgt ttgtttcacg aacatccctt tttttccgta aacgacgaaa cttggacgtt
    69181 ctttgatgcg gaaataactg gattttatcg aaattttcat atttccatag aaaaaatcca
    69241 gatcgaagta atcattcatt cgtcctttcc ctaaaagttg acgtacatca tagctgatat
    69301 catctggttc gccgaaataa gaaagaactt gatctactgt atgacaagca tgtccatata
    69361 aatagctgtt cgcagtagaa aattcatgcg tattttctgg tacttccggt ctgaaataat
    69421 cataatgcat ttctacttct aaaatatccc ctaattttcc gctttcgatt actttttgga
    69481 ctgtcaagaa gtcagaatcg aaccgtctgt tttggtaaca ttggataaat agaccttttt
    69541 cttttgctaa tgcaaataac tcttctgctt cctttgacgt ttctgcaaaa ggtttctcta
    69601 ctagtacatt cttaccatgt tcgagtgcca tttttccata ttcataatga aattgactag
    69661 gtgtagtgat gacaactaat tggatctcag gatcatccca aagatcagac agctgatcag
    69721 tatattcgat gtcttcgaat gttttccaca ctggttcaga tggggaaaaa atttttttga
    69781 tattgatttt gttcgtaagt tttcttgaaa aaggcaaatg atagcgattt gtactctttc
    69841 cattgccaag ataagcgatt gtaagcatga gtggtgcctc cttttattga tgttttcagt
    69901 atatcctaga aaagcgcaga aagtatttat aatagctatt ctggtaaaaa agttcagaaa
    69961 aacacttgtt atcattcggt ttggtgaaat taatgttcaa agtaaggata aaaatcaaaa
    70021 agatagtagc ggaaccaagt gtttatcagt aagatagaat ttggaggtca gatcatgctt
    70081 attgaagaaa aactaacaaa acaagagttg tttaccacga cagagaaacg gattgtcgat
    70141 tacatccgta ggaatatcga agctgcagtc tacatgacga ttgaagaatt agcaaaagct
    70201 acgtatactt cccattcagc tatcattcgt ttatgcaaaa aaatgggatt cagcggattt
    70261 aaagaattcc gtttcgagct ggggcgggaa gttcatcaat tgattgctca gttcaatcaa
    70321 acgattgatc ctaattttcc tttttcaagt gaagatagca ctcagcaaat tgcaaagaaa
    70381 atggcggatt tatcgatcca gtcaataaaa aaagcacaat tgcagattga acatgaagat
    70441 ttagatcaaa tcggtaaagt attgaacaag gcacagcgaa tctttctttt tgcaaaaggt
    70501 gattctcaaa tcacggcaag gaaattccag aataaaatgg tcaagttgaa taagtttttg
    70561 atcatggctg aagaatacag tgattcttct tggaatgcag ccaatttgac tagcgaggat
    70621 tgcgccattt ttattagcta cagcggtcgc atccatcatt atgaacgaat aatgacctat
    70681 ttgaagcatg tagaggcccc taccttgctg attaccggaa atcagcattc agaaatggcc
    70741 aaacaggctg atatgtgtct tgttatatcg caggaggaat atgattttgc taaagtagcg
    70801 actttctcct ctcaaattgc cttcgattac gtattaaata cgttattctc agtgatatat
    70861 tctcaaaatt ttgaagagaa tatccgcaac ttgaaaaaca aacaagaatt gatgcaaaaa
    70921 ggccttctta aagaatatcg gaaaacttaa gaaaagatcc tcatttagta ataagaaaga
    70981 tagtgtttga taggctctct ttgatatcat cataaaaaca ggctgaagtt ttctttttca
    71041 aacctcagcc tgtttgttta cggaacgatt cgaatagata tattatagaa atgaggaata
    71101 gctaacttct gtttcttatt ttgaacgatt gacgaaaaag atatataaga aggaggaaaa
    71161 tcagtataca tgcagctaac aatccataca ggaaaaatcg tttgttctcg gatactttct
    71221 gtacttcttt ttgaacttct tttgcatgat aaggaacccg gtgccctctg acaagtaagc
    71281 gatgactgtt gaccatataa ggtgtacaag ttaggagtgt cacgaaatcc tgcccttttt
    71341 cgattctcag atcttttgta tcagtcggtt ctaccgtctt gatctgatcg acttgataag
    71401 cgagtgtccg tccattgatt tcgatataga aagaatcacc taaagtcagt ttcggtaagt
    71461 ctgtgaacaa ctttgcttga ggcagtcctc gatggctgga aataacggca tgtgtatttt
    71521 ctccccccgt aggataagac gttccttcca ataatgaggc acctttttct agcagcacag
    71581 tattcgtttc atcaaaaatt ggcaaatgga cattgatctc agggatcgtc aaaataccga
    71641 tcgtatgttt ctcaaaatag gttctatcct ttttcgcagg ttcttttttc ttagtaaagg
    71701 gatctgcacc tggatttcca ccttcttttg ctaattgctg gtttttcttt gtcatgtttt
    71761 cttggatttt agccatgact tcttcatttt ctttgaccgc ttgttgctga taatgagaga
    71821 tgatctgctg atccagataa ttattcagcg cgtcgctaac aaatggataa gctagtatcc
    71881 ctattcctga gagaagcaag aaaagcatca gcagatctag aagtttcctt ttctttggtt
    71941 tcatttgtgt tctccttgtg atgactgttt gataataaaa gaaaaaggag catttgcgta
    72001 atccgctgct cctttttcca attcttgcaa aaagactaaa tctgactgtg cttgcgtcta
    72061 gcaaagtaca gtccagcaat cagtagaagg actactcctg caccgatata cacatagatt
    72121 cccttaccgc ctgttgaagg aagtgtacct ttgtgtttat ttggtatttt ttcaggagaa
    72181 atcaactgtc ctgctgttac ataagattgt tcatcgatag taaatgctac acggtttgtt
    72241 aatggaacat atttttctgg cgctttcgtt tcttccagat agtacgtgcc atattttaga
    72301 cctgtcacat cgattaaacc gttacttgtg gttgtaaaaa ccgttgctga ttctttcgcc
    72361 gatacccagc tgacggcttt tgtggatggg tcgatcgata aatatttcgc tgtgtcacta
    72421 tcttgatcac gaacgacgaa ttctgctcca gcaagtgttt ggtctgatgt aacgtcacca
    72481 tctactttaa caaatcgttt gcccccagta acgacatcga ctgacggtgg tgtttgatca
    72541 tttgtatgcc cgttatcgac atttgcttgg ttagaaaatc ctttggttgg atctgctttt
    72601 tcgttcaaat gcatatagta aacgaatttc aatgtaccgc caggagttaa tgaaggaata
    72661 taattcggat caactgaaac cgtgaatccg tctgtttgct cagtgacaga ataatttact
    72721 gggtcgattt ctttatttcc atcatataag gcataagcat acgttcctga agaatcatta
    72781 tcaaatgtta aagcagcgtc atgagtatcg ataagtttga atgttgtgta cttgttttgc
    72841 gttccttctt tatcagcgat acctaatggg atattgacag aaatctcata ttgaattttt
    72901 tcaccgattg cgacatcttt tccattcaat tgaggtgttg ttttatcaac tttagacgta
    72961 tcatttttga tggtcttttc tactggtgtt tggctatttg ccaggatctc aaaaggcgtg
    73021 attgtttgct tttcaatcat ttccgcatta tcaggagctt ttacttcttc taaattatat
    73081 tttccaactt ctaaatgatt aacgatcaac tggccttttt caatagatgc ctcggcaaag
    73141 tcattgttgc cgatgtcata agaatgacca gtaatgaaat gtttggcttt ggtttgatca
    73201 gttgtccaag tgtacaatcc atctgtgaca ctttggatgt attttttgac gcttggtgtt
    73261 ccttcttctt tagaaataat aaattctgct ccatttagtg cttcgttttc ggcagtaccg
    73321 atttttgtaa ctttcaacgt tccatcatta ccgactgtat ttttagggta gagatggata
    73381 gtatctagtt cttctgtccc gtatttataa gagccatctg cttgtttgat catctcatat
    73441 acagggaaag ctaaaaccat gtttgcggca gctgacactc cgtcttttgg ttcttctttg
    73501 atcgtgtaga ctgcatcttt cccattttgt tttttaggta aagataaagt gacatttcca
    73561 tcagcatctg tcgttcctga agcaactggt gtaccaggag tcaaagactg gactgcttgt
    73621 tttgctgcat ccacggacgc tcctttatct cgttgcgcat aaaattcttg agtgacgtta
    73681 taaactgaaa atgaaatatc ggctaatcct tggtattgat cgaattcgct catttctttc
    73741 ccgctgtttt ggattaaagg atcgggtaaa tcagtcattt tctttttatg aaggatgact
    73801 tgagctgctg tctcctctgc aaacactttt tttgcgccga agctgtttgt gagtaatggt
    73861 aaaataagga aaaggactcc taacataacg tttatttttt tatgattttt cattttttca
    73921 ctcctgttct ttttttgata aacaaccaga ttgcaaagct tgcgaatacc ataccaacaa
    73981 cgcctaaaag tgtatttttc gtttcgtttg tttttggaag aaatggacgg ctattttctt
    74041 ttttattgac tactttcaat atactgtccg cctctttatc ctcagaaaga aaagttgaaa
    74101 tggtaaacgg aatttctgtt tcacttaaaa tataaccaga aggtgcttcg atctctttta
    74161 atcgataact tcctgttttc aacccggaaa ttgaaaaagc gccattttta tcggaaatca
    74221 ggtgaagcgc atctgattcg ttctttgtcc acttgtatcc gttggctgtt tgctggaggt
    74281 aatttcctgc tttgttttta ataaggaata ctgcgccagc taatcgttta tctggtttat
    74341 ttgtctcgat tttgacaaat tgcttactcc ctgtatatac agagactttc tttgtactga
    74401 caccaaaacc aaaatccagt gttccgttgt tgttgatttc cttgttcgcc tgtgctgtac
    74461 tgcttagctg catctgataa gaaatggtca gtttttttcc agcatatttt tccaacgaag
    74521 ggatcgaaaa taaaacatca aatccgtgag gtttcttgtg tatgacaaag ccttctgtca
    74581 gcttttctcc attcgatgaa atcgttaaac tattaggtaa aaacgttaat gcttcatccg
    74641 cactatctga caattcgaac ttttgatagt caaggatatt tacaggaatt gtcgtatgca
    74701 aggaataagt gattttttca ccaatcgtaa aatcatttct aggctcttct aataccttct
    74761 caaaaggtgg atcagggtag tcgttttctt catttttagg atacaaatgg atagttgaaa
    74821 gtttttgatt gttttgtcca tgtacaggaa gaacaactac catattctct gccttttctt
    74881 tgacgacttc tggtactttg gattcaatga aaagatacgc tttatctctt ttttcttgat
    74941 ctttagcggc cagagaaaaa gaagcgatac catcttcgtt gttaagagtt gtagttgttg
    75001 cttctgcggt aaacataccg gaagacgcac cgttttttgc gatctctgct tgtgcttctt
    75061 ctaccgtttt gcccttttcc cgtagatggt aaaaagaatc tgtgacatca taaacttgga
    75121 atgtgacacc atttaatcct cgatacgttt gtaataaagc tttttcttgt ccgtcatttg
    75181 gatgattttt cggcagttgc ccgtttggga aaagcaattt gtgtaaagta atctgaacca
    75241 tttctgtttc tgtttctgtt gctacctgag taaaagctgg tttaaatagt aacaagaaga
    75301 gacacatact aagccaacca agttttttca tatttagctg ccccctcttt cttttttcaa
    75361 aaaaagatac caaatagaaa acgcacaacc aatcatccct actagataga ttcctaaacg
    75421 gccaattcct cccgtttcag gtaatggtac ttttgcctga ttcgtgatgt ctaaagaaat
    75481 ctggttgttt ttggctcctg gtgacagaac agattcatga tcttgtccat ccacttgaat
    75541 tgacccatct tcgtgtataa ctatagtaac tggctctttt agaccttggt atccttctgg
    75601 tgtaaaagtt tcggtcagcg tataagttcc aggttttaaa ttttcgaata gaaaggtatc
    75661 tgtttcttgt ccatcttttg gcgattctaa gtccatttct ggtccctgca gtctgaattt
    75721 tgctcctttt aatgtctgtc cgttgtcttc ttttttgtgt accgttagat caaacgcttt
    75781 tagtcgattt tgatgagtga gcgtccatac attatttgtc atctcggtat tttttcccgt
    75841 gtaaatgatt tttccatatt tatcgatttg gaattcataa tttcccggcg aagtatcata
    75901 tccggcagga ccagctgttt caacgactcg atatttacca ggtgtgagtg aatcaaaact
    75961 ggcaagacct ttttcattcg ttgtttggct gtcaattggc tgataagtac catttgcttc
    76021 ttttttctgt agggaaaatg ctgctccttt aagatttatc tctttgtccg tcccttgcat
    76081 cgcatactta cgtactgcta caggaacttc aacaaaagga ttttcaatag tcaactggat
    76141 cgtatcatcg gaagtagtga ctgtttttcc atcaatggtt accgtaccat cagaagcgat
    76201 cttgatttcc caagtagtct ttttgcttaa tccatgccct tctggagctt ttgtttctgt
    76261 cagcgtatag gtcatttctt tttgcaattt gacattttct ggaagagaat aggttccgtc
    76321 gccatgatct gttagtaaag tatcaataga atctcctgtt aatttgaaaa cagcgccaat
    76381 aagatccttt tcacctgtag aggaattttt cgttattttc aagtttaacg gtgtgaattg
    76441 tttagtattt ttccatgtca ttgcatctat ttgttgagaa tcgtatcctg gtacaggtaa
    76501 ttctttgatt gtttggtaac tgaatgcttg accttgatta ttgtattgag gtagtgataa
    76561 tatctcttga taactttctc cgctatttgc agataatttg tcaatgtctg cacgttccca
    76621 cgtatttgtt gtatctttag ctggtttaat gattcgaata tatccgtttt tccaagctgc
    76681 agcatttgtc gtatgttccc gttgaatctc aaaagtaact tgatctggac gatcagctag
    76741 attgttgtca aattcttccc ataacttttt gatgtgaaga ctgactccgg gagctttagc
    76801 agatggtata ccgaattcag ctaattcatt ggtatcaatg tttggctgga aagttgtcct
    76861 gccgttcatt tgataccaga aatttggatg gaagtcctca ttttctgttt ggattctcac
    76921 ttggtaatgg atttggattt cttggtcttt tcctaaatag atctgattgc tcttgatggt
    76981 atttccttct atggaaatag atggagtgac cgttgtagga cttgtcccca cactcttgac
    77041 tgaaagtgta ccaggctgat aaatgaatgg ttctgcgatt ggatcattta tttgtccatt
    77101 gcttacagtt gctgagatct gtacagcttt tttggctagg tattcagaga tatctgttgc
    77161 atgatcagct gattcatagt aaagatcgcc tttttcatct gatgaaacca tttgtcgcat
    77221 acgagactct acttctgctt ttgagagacc agctgccgga tcgctttgaa gttggatgcc
    77281 aagaccatgt atttcgattc ctcgttcttt gagtgccatc gcttctccga tggttgcgat
    77341 aaacgtactg tcgattcttc tggatagatt gttttggtca ggtgcatcat agattcttga
    77401 gattagagaa gtatttcccg gccgatcttg cgtattagaa aactgagttc cgtaataatt
    77461 gctgcttgat tgtgcgtgta cccgctgtac tttataggaa aatgttggta caccatccgt
    77521 cagcaaaacg atcacttttt tatgtccatt tggaacggat agcatgcttc ctgcatctct
    77581 tagtgctttt tgtgtaaaag taccaccatt tgtccgtgaa ggtgtaatgg attttacttg
    77641 atttttcact gaatcaaatg aacccatctg tactgcaccg ttactgtagc tatatccttc
    77701 gcttgagtag ccgacatatc ccatattgat tttgtctgtg ataccgctat ctgctaaagt
    77761 atcgacaaaa cgatcgacac caatctttac ttcaccgatc cgattattgt cgttcatact
    77821 tcctgaccag tctacgacca atacgagatc aagaggcgtg atatcttttt gtacatttcc
    77881 acgagcattc aaataaacat caaacaatcc gggtgtactt gtttcctttg catactttcg
    77941 tatcgcatag tctgcttgat taccggttcc tccatattcg atatacgaat gggtccgatc
    78001 attaggatct ccattccaag aatttatacc atcccattga tttgttccgt ttttattgcc
    78061 ttgatgatca agaacatttg tatttcctgt aggttgccaa ctggctttag gataagtgcc
    78121 ctgatcatct gttgtatatt ctgtaggaat cgtttgatta gatggcacac tcacagctgg
    78181 caaggataat gtaggcaatg taaatgggct gacagaattt tcgttttctt ttgatgattc
    78241 ttcttctatt tcgtctggct ttggtactga cacatctgta tctttcttat tttctgtctc
    78301 atcaataatg tcatattctt tattatcgac gatcagcttg tttgcctggc tgtggtaaag
    78361 tgctggatcg attggaaaac tcagatcgat agtttgttta gtgtttgatg agatttccaa
    78421 cgtaattttc ccgctattta cctgataagc atagccatct ccttcttttc tttccacatc
    78481 acttaagtaa ttttcgacta gaccaatttc tttttctatc ttttcagcac tggtgttatt
    78541 cgcatttagc ttgatgttca gtgctttttt tccagactga tccgaaatga cttcagctga
    78601 aattgtttct aaaactgttg gatcatctgt agtgtctgct attgcagata atggcacaaa
    78661 gtttgataaa ctcaatatta tcagcatgaa aataactttc agtttcttcc ctgtggtcgt
    78721 catttttccc ctcctttttc tttttttctg ttttgacgtg aatagtgaaa attattaaaa
    78781 taaacaggcg ttacataatt ttatttattt taatatgata attattatac gaagggcgct
    78841 aaagggaatc acaccaattt tcataccaat tggtttcatt tatgaagttg attccttcga
    78901 ttaatgagcg tttcattgaa agaaaagggt tgagggagaa aaacatatga tcaggttgtt
    78961 ggaaggaaac tatagaaaga tggaaaaaat cattcgaatt ctgtccattt ctgacaagtg
    79021 gatgactaaa aaagaacttg ccaaacgaat tggtagttca gaatctacat ttgtaaggta
    79081 tatcgaagag atcaaaatcc gctggggaac ggatgtaacg attcaatctt cacaaaaatt
    79141 ggggtatcgt cttgaacatt tgaatgtacc agcttattta aatgttctga tggaaatgtc
    79201 gcaaagttcc acaaacagtc gtttattaaa tgagattatt gtcaatccgg gtaaaacgat
    79261 tgagtattat tgtgaaaaaa tttccatcag ccggtcttct tttacacgta agttgaaaca
    79321 atgcaatcaa attttagaaa gctatttatt aaaagtgatc gttgaccaag gttttcagtt
    79381 aactagcctt aaaagtgagc tccagttgcg tatctttgtt acctttttct ttttaagtta
    79441 ctacggaaga cgcacgttgc catttccaat cgaaaaaaag aagatcaaag aaattatggt
    79501 caagaataat tgtcagatga atttgtttca ggaagaaagc ccatatgagc aatctttctt
    79561 tattatgtat tttgttgtgc atctcatgag agaatcccaa ggaactccat ttgaatggaa
    79621 agctggagac tcttatgtac agttgataaa tatcgataaa aaagacttct taatcttgaa
    79681 aaatctctta ggaaaattga agtacagcag ctatataaaa gtagtgaact attttgtcaa
    79741 tacgattttt tcagaatttt cggagaaaga aaaaaatgaa atcagtgagc agatacgaaa
    79801 aaatatgtcc tactgttcgt tttcatccgc tgattgcaaa gaaaaaaacg aagaatatgt
    79861 tgttcaatta ttaacgcaaa tttatttttt ctcccgtatt ttcccatacg atacgactca
    79921 tttgacgatc cgtgcaactt actttgcaca gcagatgcaa caccgccaga tacgtctata
    79981 tgctggattt cgtgcagaac ttcaatttta ttccactcta ctgaatcaga atctgattta
    80041 ttatttatct agctatatct tttggatgct tatcggtaat cctgaaattc accattatac
    80101 ttctgataaa aaaatactga ttatcagcga cttaagtctt cgacatagtc aatatattga
    80161 agaatatatc agtgatattc ttgctgtgca taaaattcac tctgagacaa ctgctattac
    80221 tgaagatcag ctgtcgaaat acaatcttct cgagtatgat ctgatcgtta cgaatcaacc
    80281 cattttgaat gcccatgttc ctcatatatt gattgatgat agtgtgtcat tcgcaaatga
    80341 agaagaactc atccgcttat tcgagttatg aataatcaaa aaacagctat gtataaacca
    80401 ccctgataaa aatttcagga caaatacaca tagctgtttc tttttattgt attccttcag
    80461 caatccaacg agatttatag cgaaagtctt ttaacaactc ttcttttgtc caattatttg
    80521 caatgagatc cgtcaaagtg ttcattacga gggtcatgga aaagtatagg aaactaactg
    80581 cttcttccga cgattgaatg gagaaatgat tgattcttaa taattccagc catttttcgt
    80641 tcattggaga atcagccgat agttctctac gtttggttgt ctgctgatca tttcgctggg
    80701 ttaacaagta taacctttgc caatagatac tttcgtgatc taagtcgcag caccactcta
    80761 aatatttttc gatccccaaa aagaaatgtt gtttgttttc gctaatgaat tttaagatat
    80821 cttgatggac tatgtgagaa ctgcttttga tcgtatacaa ataagcatct tccaaatctt
    80881 gaaaatattt ataaaaagca ccgcgcgaca tccccatctt gtcaacgatt tctgagactt
    80941 tgacttggct gatgtgctgt gagcaaaata tctccagtaa taggtcatcg attctctgtt
    81001 tctttgcgtt cgataaattg aaaaaagttt cttttggcat ccacatctct cctttatctc
    81061 tgattatacg tggatagccc ttcattgtca tgaaggattc attccttctt tttctcttct
    81121 tctgtcaagt acccatcttc cattcgataa acgcgatcac tccattgaat catacggaca
    81181 tcatgagtaa ccataatagt cgctttttgt ttctcatgag cttctttaac tagtaatttg
    81241 acgacttcat atgcatgatc tgtatccaaa ctagctgttg gttcgtctgc taagatcaag
    81301 cttggctcat tatataaagc gcgagcaatt gccactctct gtctttctcc accagaaagg
    81361 tctttaggat aactattttt aagtgactgg atatctaaag attgcagcaa ggaatcgatt
    81421 tttgttgaat cttctttttt tgaagtaact tggtcaacta gttcaaattg ttcctttacc
    81481 gttaaaaaag gaatcaaatt agagctttgg agaataaatc ctatttcttt aaagcgtaaa
    81541 tctgctcgtt ttttttctgg aagctcagtt agtgagtgac cgttgatcac tatttctccg
    81601 gaagtcggtg tttgcaatcc tcctgaaatg gtaaggaaag tacttttacc tgaaccagaa
    81661 ggaccaatga tgctgacgaa ttctccttcc tttacataaa aatcaattgc tttcaaagct
    81721 gagacctttg tatgaccaga accaaatgtt ttggtaactt ttttcatcgt taatattttt
    81781 ttcattttta ttaacctcct attgctgtaa ttgggtctac tttggttatc gtacgtatcg
    81841 aaaacaatcc gcctagcatt gcgacaatga tcaaaatccc actatatagc aaccattgtg
    81901 accaaaaaac agcaaaaggc atcgcgcttg gtaaaatcag actagtcaaa taagcaaaca
    81961 aaagagcaag cagaacgcct accaccccaa caataaagga ctgtgctact aaagatttag
    82021 cgatgaagaa atttttgatc ccttgtgctt tcattactcc aaaaatagca gtcttctgaa
    82081 gtgtcatcac gtacatgaaa ataccgacca cggcagcaac cactaagaac aaaaagtata
    82141 tcatcgcatt taaggtcata ttttgggcag aatagccagg aatactttca atgaatgtcc
    82201 caatagttaa taactgtaga cccttcgatg ctttttcttt cgaaatttta gctgaatcct
    82261 ttattacgat cccattgatc ggctgttctt cttcagaagc aaacggctgt tgtccatact
    82321 tcaaagcagt ccacgtatct agggacgcat agatgacggg agaaactgtg taataagttt
    82381 caggaaagat accgacaatc gtcaaaggat cgtcgtaact gccaattttg atcgtatctc
    82441 caattttata gcctgaatca gccagatttt gagagatgat gatttcattc tttgttttaa
    82501 attcatgccc tttcgtgagt tttggtaata aaaatgcttc tttcgttgtg ccgaaaactg
    82561 taacattttc tttgtttttt cctttgattg ctccgctgta caatccgatt ggtgctttct
    82621 ctcctccttc aatgtatttc agatctcctc ttgttaattg tgaagctgca aatacttgat
    82681 ttgcatcctc cgacaaaaca atctcttgtg cgtcccaatc atcgattgct tttttaaact
    82741 cttctgaaag tccattcgct agtcctgaca acatgaatac gacatacgca atcaagaaca
    82801 taataccgac gatcaagcca tatcgtaatt tagaatagcg aatttctttg atagctagaa
    82861 acatttgttt ttcctcccta tgatagattg atagtgacaa aatgtcactt gttgaatagt
    82921 gtaactctaa agtgacaatt tgtcacttgt gttgtttttt tcttatcaat aaattgtcta
    82981 agacatcttt cgataaaacc ttaacatgag tcataaaaaa tttatttaag ccttatttat
    83041 gctttccatg ataaactaaa gtgaccaaat caatgaggtg ggaaaatgat taaactatta
    83101 gtagtagaag acgataaagt attatccaat aatataaaag aaatactcgc tgcaatcggc
    83161 gagataacac aagtttatga tggtagtgaa ggactgttcg agttggaaag tggagtttat
    83221 gatcttgcaa tcttggattt gatgatgccg gaaatgaatg gatatgaagt gttagcaaaa
    83281 atacggaaag aaaaaataca gactccagta ttgattttga ctgcaaaaga tagtttggaa
    83341 gataagattg aaggatttga acgaggtgca gatgattatc taacaaaacc tttctatcga
    83401 gaagaactga tcatgcgcgt gaaagcatta ttgaaacgct cgctaggtct ctttgatgaa
    83461 aatgttctga agtataagga tatcagttgt gatttaaaaa gcaatgaagt cttgtataaa
    83521 gaacaagttt tgcccataca aggaaaagag tttgaattgc tcgtttattt tttacaaaat
    83581 aagggaatca ttttgacaaa agagcagata tttgaccgga tctggggatt tgattctgat
    83641 acgacgatta cagttattga agtttatatg agcaacttac gaaaacatct gcgaagtact
    83701 ggattggata aagaaatcaa aaccttacgt aatgtcggtt atatactgca aagggtgtga
    83761 tgcaatgaat ggagatatta cacgaaagca acgtagtcgc ttttttgcga caaatgtagc
    83821 agcatttgct tttatctttt ttcttttggg attcattact ttacagatat taaaccaatc
    83881 tgcatacaga gaaacagatc tgtcattaga gaaaataaat tttgattctc gaacagtaca
    83941 attagagata caaagatatc agcaaggcga tcccttttta aacccgactc aaacggaaca
    84001 aaacagaaca aacatggaac agccattaat ggaaccatca aatgaccgtt ttaacactca
    84061 agtgatcttg tggtctaaaa atggtgagat attgaataaa gcagctattg gtgggcgttt
    84121 caaccaaatc aaagaattaa aaatggatac gaaaaatctg aataccatcc aaaatattga
    84181 attaaatgaa gacagtggct catctgccct ctctttccgt tcgattacga aaaaagcgga
    84241 gacgaatcaa gatggcgttg cctacatcca aattttagaa aatacaaatc aaatcaagaa
    84301 ttcattagcg acttttcgca cgattatgat tttgtgtatg attgtttttt ggattctctc
    84361 tattggtatc agttattact tgtctagtct aagcatgcgc cctattattc tttcttggag
    84421 aagacaaaaa gaatttgttg agaatgcttc tcatgaattg cgcacaccgt taacgattat
    84481 tcaaaatagt ttggaacatc tttttaccaa gcctaatcat actattattg aagaatccga
    84541 aagcatcgct caagcattgt cagagacgag gcgcctcact ggattgactt cggatttgct
    84601 gacaatcgct cggaatgatt ctgatcagca gctgctttca aagcaaatga tcaatacaca
    84661 agaatatatc gaacaacttg ttaaaccatt tcaagagatg gccatcatag atggaaaaga
    84721 gtttattctc cataacgatg caacattaga agtaccaatt gatgaaaaaa aaatccatca
    84781 agttttggtt attttgctgg ataatgcatt aaaatatacg aatccagaag ataagatcat
    84841 tttggattca tctgttaacc ataaagaatg gctgattcac gtaaagaata ctggcccttc
    84901 tatcagtgaa gaagatcaag caaggatttt tgatcgattt tatcgggaag atcaatctcg
    84961 ggcgaaagag actggcggat acgggcttgg cttggcaatt gcaaaacagg taatcgaaca
    85021 gcatcatgga cagatttctg tatccaatta tcttccacaa ggagtcgatt ttaaagtcca
    85081 attgccgttg aagcctaaaa aataatgctt atccctaaaa aagggctgtg acaaaaatct
    85141 tgtcacagcc cttttttgtt gcgaataaac ggtgttccag aagtagcttc ttcggaaata
    85201 agccgaaatt tctttaagct gaccacttct gtcacaacct ctttagctta cgcttacgat
    85261 tttttattgc ggtcttcaat gtgtacatca ccgcttgtgt caatatccaa ttcttctcgg
    85321 ctaacatctt ctgtcacttt ttcaacatct tcatgttctt ctttatgaat cccaacttct
    85381 tcacgaataa ctgtatgttt gcttacatct acttgctctt ctttgattgg gatagtaatc
    85441 gtgtcatctt ccaatttttc gtctgttccc tgtgaagatt gatctgttac tggtttgcgt
    85501 tcgatgacga tttcttcacg tttgaccggt acttctaccg tttcagtatc gttgaccaca
    85561 tgtttgtgga tgtcgacttc tccagttgtc acatcatgtg tatttacatc taatttttct
    85621 tcttttagtt gaattgtatc atcatctaga tttggtttgc gatcgatgtc ttcagtcttg
    85681 cttgtaccca ttgtatcagt ctcgccaggt acgtccatcg gatcagttcc tggtgtcata
    85741 ttcaatggat ccgttgtatt ttgaaagcct gtcgtgccac ctacgtccat tggatctgtt
    85801 ccagtgccag tttctaatcc agtccccatt gtgcttgctg ggctaacagt atcttgtgta
    85861 tccattgtat cttctgttgt ttctggctga cgatagcctt ttactgtgat gacaaatttt
    85921 ccatcagaaa tatctcctct atattgatat aaaggatcat tttctggtgt agccgtctca
    85981 gaatcatagg tatcaaaaga aaaagtatct tttatttttt cccataaaga acggtcttct
    86041 tcaccatcca tccgattttc atctgtttca acatctatac cagacaatcc gtcaaatcct
    86101 agtctagatg ctgcttcatc agtagtataa ataacgatat catctcgttc atacccttcg
    86161 ttacgcaacc gttcaattac tgataatgct tcttccctcg tactatagct tccgatgacc
    86221 gttaaatttt tctcttccat gtaaattcct cctagcaaat agatttatga ttggtatatt
    86281 gttacttata aatttattct ataggagacg attgttttct acaaatattt agattggaat
    86341 ttgattaaaa caatttaatt gaaatttgaa aacatttatg ttaatgaaag tcatattcta
    86401 ataaaatgtc atttgtttct atatgaattt ttatgaaaaa tttcatataa tttccactcg
    86461 ttgtgatggt ttaatttatc caatccatca ataagcaaac aacttatata aaaaaggatt
    86521 aattctcaat ataattgctc ctaccataga ataaatcttc atgtaaagta atgaagtacc
    86581 aactatttct aatacttctt taagaattat cccaacaata tcgttagaca aaccattatt
    86641 gaataaatgg agagccaatc gattctgaaa aaatgttttc taatttttcg gaaataaaag
    86701 aaagagcctc ctgccattag aacgaaccaa atccatttca ttgctcatga agtaaccaca
    86761 tagctaaaaa gaggataaat caattaaaag atcaaaagaa tgactgcact aataaaataa
    86821 ctaaaaatgt atcttcttac ttcatatctt ttagctagta cttagttaaa aatttgcttc
    86881 ctaagatcaa gacaaactgt ctatcttcat ttgatgaaat gcggtaaaat atagaaaatg
    86941 aacactattg gagggaattt gtaatggaca gcaaaactag aaaacaactg caagaaaagt
    87001 taaagcaacg tacacacttg ctcccttccg tctttcaaca gtttttagaa gaaaatcgtt
    87061 cttccctttc attaggcagt cgctatgaat acgcaaaaga ttttcatctg tttactgatt
    87121 atttgagaaa agtattttct gaagaagtgg atgatcagct gattatccat ttagaaaaac
    87181 aagattatca gaatttctta gctaaaatct atcgacatac tcgttcgttc caaactacag
    87241 cgaaccaaga aacggagcaa ttgtttgaaa atagctatta cgggatttca aggaagcaat
    87301 attcattaaa tcatttttta cgatttttgt atcaaaaagg actgattgaa gaagagattt
    87361 ctcttttggg tacaagttta ccggaaacaa ccaaagcagc tccgcgatat atcgatgcag
    87421 aacttttcaa agattttgag catttgttta tcccgattga aggctttcaa acaagcagag
    87481 aagctagctt tgaagaaaag aatagaccga ggaaccttgc aattactgcc attcttctgt
    87541 attgcggatt aaagatccat gaagtagtag aacttaaacg taaagatgta tctttgacca
    87601 agcagattct taatctgaat agaaaagaaa acagactgaa taaagtacca ataccaaaag
    87661 aagcgatgcc atttctggag aactatttta agttaacagc acaaaatacg gacgaaaatt
    87721 cttttgtttt tcgttcctca catgatcagc aaatttctcc tcggactatt cgccaaattt
    87781 tgagcaaaat tacagtatat aaaaacgtat cgccagaact atgcagaaaa acatatcgtt
    87841 attatgcaga actatattta gatgatgctg acgcggtaaa ttatttatgt ggtaatcgat
    87901 acctctcatc ccattctttt caagatatct gggaaaagat ggttgatttt tcttatcacg
    87961 aattagcggc attcgttcgg gtttcttcca tataaaacaa atgtatgatc tttttttcac
    88021 aataaactat gttattatat aaaggattat gttacgatta tcttgaattt gtatattact
    88081 taacaaaaga taatggagtg tgaatgatgg agaccataac gtattcccct ttgaacttat
    88141 ttacgaattt tcaagaagct gcagctaact tttccgagac cccgattatc tttgatgagc
    88201 cactttcagc tttcccagaa ttaggacttg aaacaactta caaaaaatgc tgcgaaagtg
    88261 tgttgaaacg ggcttatcaa ttggctcatc ttggagtgaa atccggagac aaagttatta
    88321 tttataagag ttccgctttt gacacatacc ttctagctgt ttctgtgtct taccttggtg
    88381 cagtgcctgt catgacttct tatcatctac caacaacaac aatggaagta tttatcgatc
    88441 gtttagaaga ccctttcatt ttatttgatg atgagacaaa aaagcgagtg agagaaattt
    88501 caaatggaac aaaatcaaaa cagattc
//
LOCUS       DAZULR010000004        84114 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.004, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000004 DAZULR010000000
VERSION     DAZULR010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 84114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 84114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..84114
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.004"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            277..1278
                     /locus_tag="ACG8ZV_000264"
     CDS             277..1278
                     /locus_tag="ACG8ZV_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HFS4995634.1"
                     /translation="MTSTVFIILLGFVCRKKGIFSESVGKILSKVVLTVALPALAFRA
                     FMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYKGDKQTTLRVLTIFGSTTFF
                     GTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGLKMEAKNIKAMFVNPIIIAT
                     FAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPWLFQPMDYLAGLSSPLAWLA
                     IGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILAVLTATNILPVNFEALATIV
                     IMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVLTPVWIVVLQMIHGIGLFS"
     gene            1297..2316
                     /locus_tag="ACG8ZV_000265"
     CDS             1297..2316
                     /locus_tag="ACG8ZV_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacid dehydrogenase"
                     /protein_id="HFS4995635.1"
                     /translation="MRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIVSAKDH
                     DAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVPSYSPN
                     AIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRIGLTEA
                     VLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQMINEG
                     FLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSFKPWET
                     IPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNEVSLPK
                     ARQLR"
     gene            complement(2418..3134)
                     /locus_tag="ACG8ZV_000266"
     CDS             complement(2418..3134)
                     /locus_tag="ACG8ZV_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFS4995636.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(3103..3888)
                     /locus_tag="ACG8ZV_000267"
     CDS             complement(3103..3888)
                     /locus_tag="ACG8ZV_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFS4995637.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            complement(3879..4628)
                     /locus_tag="ACG8ZV_000268"
     CDS             complement(3879..4628)
                     /locus_tag="ACG8ZV_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFS4995638.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            4926..5450
                     /locus_tag="ACG8ZV_000269"
     CDS             4926..5450
                     /locus_tag="ACG8ZV_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HFS4995639.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            5466..6965
                     /locus_tag="ACG8ZV_000270"
     CDS             5466..6965
                     /locus_tag="ACG8ZV_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HFS4995640.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(7053..7655)
                     /locus_tag="ACG8ZV_000271"
     CDS             complement(7053..7655)
                     /locus_tag="ACG8ZV_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFS4995641.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            7759..8715
                     /locus_tag="ACG8ZV_000272"
     CDS             7759..8715
                     /locus_tag="ACG8ZV_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HFS4995642.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            complement(9020..9976)
                     /locus_tag="ACG8ZV_000273"
     CDS             complement(9020..9976)
                     /locus_tag="ACG8ZV_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFS4995643.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            10150..10710
                     /locus_tag="ACG8ZV_000274"
     CDS             10150..10710
                     /locus_tag="ACG8ZV_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995644.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            10703..11527
                     /locus_tag="ACG8ZV_000275"
     CDS             10703..11527
                     /locus_tag="ACG8ZV_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HFS4995645.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            11537..12154
                     /locus_tag="ACG8ZV_000276"
     CDS             11537..12154
                     /locus_tag="ACG8ZV_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFS4995646.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            12172..12855
                     /locus_tag="ACG8ZV_000277"
     CDS             12172..12855
                     /locus_tag="ACG8ZV_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HFS4995647.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            13538..14821
                     /locus_tag="ACG8ZV_000278"
     CDS             13538..14821
                     /locus_tag="ACG8ZV_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFS4995648.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVNKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            14837..15724
                     /locus_tag="ACG8ZV_000279"
     CDS             14837..15724
                     /locus_tag="ACG8ZV_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4995649.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            15741..16577
                     /locus_tag="ACG8ZV_000280"
     CDS             15741..16577
                     /locus_tag="ACG8ZV_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4995650.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            16580..17203
                     /locus_tag="ACG8ZV_000281"
     CDS             16580..17203
                     /locus_tag="ACG8ZV_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995651.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            17200..18492
                     /locus_tag="ACG8ZV_000282"
     CDS             17200..18492
                     /locus_tag="ACG8ZV_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFS4995652.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     regulatory      18851..18948
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            19064..19645
                     /locus_tag="ACG8ZV_000283"
     CDS             19064..19645
                     /locus_tag="ACG8ZV_000283"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HFS4995653.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            19648..20955
                     /locus_tag="ACG8ZV_000284"
     CDS             19648..20955
                     /locus_tag="ACG8ZV_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HFS4995654.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMILISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            21371..21859
                     /gene="purE"
                     /locus_tag="ACG8ZV_000285"
     CDS             21371..21859
                     /gene="purE"
                     /locus_tag="ACG8ZV_000285"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HFS4995655.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            21852..22976
                     /gene="purK"
                     /locus_tag="ACG8ZV_000286"
     CDS             21852..22976
                     /gene="purK"
                     /locus_tag="ACG8ZV_000286"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HFS4995656.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            22989..24284
                     /gene="purB"
                     /locus_tag="ACG8ZV_000287"
     CDS             22989..24284
                     /gene="purB"
                     /locus_tag="ACG8ZV_000287"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HFS4995657.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(24464..24841)
                     /locus_tag="ACG8ZV_000288"
     CDS             complement(24464..24841)
                     /locus_tag="ACG8ZV_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995658.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            25097..25825
                     /gene="purC"
                     /locus_tag="ACG8ZV_000289"
     CDS             25097..25825
                     /gene="purC"
                     /locus_tag="ACG8ZV_000289"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HFS4995659.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            25825..26079
                     /gene="purS"
                     /locus_tag="ACG8ZV_000290"
     CDS             25825..26079
                     /gene="purS"
                     /locus_tag="ACG8ZV_000290"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HFS4995660.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            26081..26752
                     /gene="purQ"
                     /locus_tag="ACG8ZV_000291"
     CDS             26081..26752
                     /gene="purQ"
                     /locus_tag="ACG8ZV_000291"
                     /EC_number="3.5.1.2"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HFS4995661.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            26753..28975
                     /gene="purL"
                     /locus_tag="ACG8ZV_000292"
     CDS             26753..28975
                     /gene="purL"
                     /locus_tag="ACG8ZV_000292"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HFS4995662.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            28960..30399
                     /gene="purF"
                     /locus_tag="ACG8ZV_000293"
     CDS             28960..30399
                     /gene="purF"
                     /locus_tag="ACG8ZV_000293"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HFS4995663.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            30422..31474
                     /gene="purM"
                     /locus_tag="ACG8ZV_000294"
     CDS             30422..31474
                     /gene="purM"
                     /locus_tag="ACG8ZV_000294"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HFS4995664.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            31471..32049
                     /gene="purN"
                     /locus_tag="ACG8ZV_000295"
     CDS             31471..32049
                     /gene="purN"
                     /locus_tag="ACG8ZV_000295"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HFS4995665.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            32046..33581
                     /gene="purH"
                     /locus_tag="ACG8ZV_000296"
     CDS             32046..33581
                     /gene="purH"
                     /locus_tag="ACG8ZV_000296"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HFS4995666.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            33597..34871
                     /gene="purD"
                     /locus_tag="ACG8ZV_000297"
     CDS             33597..34871
                     /gene="purD"
                     /locus_tag="ACG8ZV_000297"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HFS4995667.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            34993..35907
                     /locus_tag="ACG8ZV_000298"
     CDS             34993..35907
                     /locus_tag="ACG8ZV_000298"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HFS4995668.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(36040..37605)
                     /locus_tag="ACG8ZV_000299"
     CDS             complement(36040..37605)
                     /locus_tag="ACG8ZV_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4995669.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(37598..39049)
                     /locus_tag="ACG8ZV_000300"
     CDS             complement(37598..39049)
                     /locus_tag="ACG8ZV_000300"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFS4995670.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(39063..40079)
                     /locus_tag="ACG8ZV_000301"
     CDS             complement(39063..40079)
                     /locus_tag="ACG8ZV_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFS4995671.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            40299..41387
                     /gene="chvE"
                     /locus_tag="ACG8ZV_000302"
     CDS             40299..41387
                     /gene="chvE"
                     /locus_tag="ACG8ZV_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     substrate-binding protein"
                     /protein_id="HFS4995672.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            41441..42967
                     /gene="mmsA"
                     /locus_tag="ACG8ZV_000303"
     CDS             41441..42967
                     /gene="mmsA"
                     /locus_tag="ACG8ZV_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     ATP-binding protein"
                     /protein_id="HFS4995673.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            42969..44174
                     /gene="mmsB"
                     /locus_tag="ACG8ZV_000304"
     CDS             42969..44174
                     /gene="mmsB"
                     /locus_tag="ACG8ZV_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     permease"
                     /protein_id="HFS4995674.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            44431..45408
                     /gene="guaC"
                     /locus_tag="ACG8ZV_000305"
     CDS             44431..45408
                     /gene="guaC"
                     /locus_tag="ACG8ZV_000305"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HFS4995675.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            45672..47096
                     /locus_tag="ACG8ZV_000306"
     CDS             45672..47096
                     /locus_tag="ACG8ZV_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFS4995676.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            complement(47138..47395)
                     /locus_tag="ACG8ZV_000307"
     CDS             complement(47138..47395)
                     /locus_tag="ACG8ZV_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995677.1"
                     /translation="MPIRILTALVNKITIRKAFYISSAFFLFSNQTYNHLFLFKNVGV
                     IQFCCKHLFYLHIVNGRTNNGFFLVSLYRILFPKKKKQLEI"
     gene            47557..48666
                     /gene="pdhA"
                     /locus_tag="ACG8ZV_000308"
     CDS             47557..48666
                     /gene="pdhA"
                     /locus_tag="ACG8ZV_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0004739 - pyruvate dehydrogenase
                     (acetyl-transferring) activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HFS4995678.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            48669..49646
                     /locus_tag="ACG8ZV_000309"
     CDS             48669..49646
                     /locus_tag="ACG8ZV_000309"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HFS4995679.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            49671..51314
                     /locus_tag="ACG8ZV_000310"
     CDS             49671..51314
                     /locus_tag="ACG8ZV_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HFS4995680.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            51322..52728
                     /gene="lpdA"
                     /locus_tag="ACG8ZV_000311"
     CDS             51322..52728
                     /gene="lpdA"
                     /locus_tag="ACG8ZV_000311"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HFS4995681.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            52890..53165
                     /locus_tag="ACG8ZV_000312"
     CDS             52890..53165
                     /locus_tag="ACG8ZV_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HFS4995682.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            53171..53938
                     /locus_tag="ACG8ZV_000313"
     CDS             53171..53938
                     /locus_tag="ACG8ZV_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HFS4995683.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            54106..55935
                     /gene="typA"
                     /locus_tag="ACG8ZV_000314"
     CDS             54106..55935
                     /gene="typA"
                     /locus_tag="ACG8ZV_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HFS4995684.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            56196..57968
                     /gene="recQ"
                     /locus_tag="ACG8ZV_000315"
     CDS             56196..57968
                     /gene="recQ"
                     /locus_tag="ACG8ZV_000315"
                     /EC_number="5.6.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HFS4995685.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            58082..58384
                     /locus_tag="ACG8ZV_000316"
     CDS             58082..58384
                     /locus_tag="ACG8ZV_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HFS4995686.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            58387..59550
                     /locus_tag="ACG8ZV_000317"
     CDS             58387..59550
                     /locus_tag="ACG8ZV_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFS4995687.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKNFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            59576..63004
                     /locus_tag="ACG8ZV_000318"
     CDS             59576..63004
                     /locus_tag="ACG8ZV_000318"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004736 - pyruvate carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009374 - biotin binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006090 - pyruvate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HFS4995688.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            63025..64149
                     /locus_tag="ACG8ZV_000319"
     CDS             63025..64149
                     /locus_tag="ACG8ZV_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP-associated domain-containing protein"
                     /protein_id="HFS4995689.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            64130..64576
                     /locus_tag="ACG8ZV_000320"
     CDS             64130..64576
                     /locus_tag="ACG8ZV_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFS4995690.1"
                     /translation="MIAVIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESA
                     KVCQLKEAFLSKKEAFENVAAYGEYAPDYREKKRVVRKAKRQLDMDEHVAAFRYSETQ
                     LQSLLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            64560..64898
                     /locus_tag="ACG8ZV_000321"
     CDS             64560..64898
                     /locus_tag="ACG8ZV_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HFS4995691.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            65017..65577
                     /gene="rsmD"
                     /locus_tag="ACG8ZV_000322"
     CDS             65017..65577
                     /gene="rsmD"
                     /locus_tag="ACG8ZV_000322"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HFS4995692.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            65574..66065
                     /gene="coaD"
                     /locus_tag="ACG8ZV_000323"
     CDS             65574..66065
                     /gene="coaD"
                     /locus_tag="ACG8ZV_000323"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HFS4995693.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            66055..67098
                     /locus_tag="ACG8ZV_000324"
     CDS             66055..67098
                     /locus_tag="ACG8ZV_000324"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepM family pheromone-processing serine
                     protease"
                     /protein_id="HFS4995694.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            67257..67985
                     /locus_tag="ACG8ZV_000325"
     CDS             67257..67985
                     /locus_tag="ACG8ZV_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HFS4995695.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            68101..68346
                     /locus_tag="ACG8ZV_000326"
     CDS             68101..68346
                     /locus_tag="ACG8ZV_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFS4995696.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            68343..68561
                     /locus_tag="ACG8ZV_000327"
     CDS             68343..68561
                     /locus_tag="ACG8ZV_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HFS4995697.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            68697..69236
                     /locus_tag="ACG8ZV_000328"
     CDS             68697..69236
                     /locus_tag="ACG8ZV_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HFS4995698.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            69229..71502
                     /locus_tag="ACG8ZV_000329"
     CDS             69229..71502
                     /locus_tag="ACG8ZV_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HFS4995699.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            71540..72586
                     /gene="holA"
                     /locus_tag="ACG8ZV_000330"
     CDS             71540..72586
                     /gene="holA"
                     /locus_tag="ACG8ZV_000330"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HFS4995700.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(72675..72929)
                     /gene="rpsT"
                     /locus_tag="ACG8ZV_000331"
     CDS             complement(72675..72929)
                     /gene="rpsT"
                     /locus_tag="ACG8ZV_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HFS4995701.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(73329..73598)
                     /locus_tag="ACG8ZV_000332"
     CDS             complement(73329..73598)
                     /locus_tag="ACG8ZV_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995702.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(73860..73988)
                     /locus_tag="ACG8ZV_000333"
     CDS             complement(73860..73988)
                     /locus_tag="ACG8ZV_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995703.1"
                     /translation="MFEKLKYFIGTIGWFLLAVLLILGLAYLLFPDLIQNVFDTAF"
     gene            complement(74068..74523)
                     /locus_tag="ACG8ZV_000334"
     CDS             complement(74068..74523)
                     /locus_tag="ACG8ZV_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HFS4995704.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(74661..76589)
                     /locus_tag="ACG8ZV_000335"
     CDS             complement(74661..76589)
                     /locus_tag="ACG8ZV_000335"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFS4995705.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(76786..77619)
                     /locus_tag="ACG8ZV_000336"
     CDS             complement(76786..77619)
                     /locus_tag="ACG8ZV_000336"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HFS4995706.1"
                     /translation="MFFANIIKAVILGIIEGITEWVPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(77811..78515)
                     /locus_tag="ACG8ZV_000337"
     CDS             complement(77811..78515)
                     /locus_tag="ACG8ZV_000337"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFS4995707.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(78538..79164)
                     /locus_tag="ACG8ZV_000338"
     CDS             complement(78538..79164)
                     /locus_tag="ACG8ZV_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFS4995708.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            79490..81865
                     /locus_tag="ACG8ZV_000339"
     CDS             79490..81865
                     /locus_tag="ACG8ZV_000339"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HFS4995709.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(81889..82380)
                     /locus_tag="ACG8ZV_000340"
     CDS             complement(81889..82380)
                     /locus_tag="ACG8ZV_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HFS4995710.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            82567..83487
                     /locus_tag="ACG8ZV_000341"
     CDS             82567..83487
                     /locus_tag="ACG8ZV_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFS4995711.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            83641..83985
                     /locus_tag="ACG8ZV_000342"
     CDS             83641..83985
                     /locus_tag="ACG8ZV_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HFS4995712.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
BASE COUNT        27279 a        14566 c        18080 g        24189 t
ORIGIN      
        1 ataatttaag ttaaccttaa aactaaactt cttaagtttg gttttaaggt tttttttgtg
       61 ttctagtaaa aatcacttta cataagtttc aaaagtttct ttaatttcct attgttcaat
      121 aagtaacaat gtaaagataa aattaaaaat gttaatacgt attagcaaaa taaaagcttt
      181 ttttattgtg aataaatgaa cataattagg aggagaaaga tgaacttatt tgacattttt
      241 cgatcgactt tgacagatat gtcgattgtc agtgcaatca cttcaacagt ttttattata
      301 ttattagggt ttgtttgtag aaaaaagggg attttttctg aatctgttgg aaaaattcta
      361 tcgaaagtcg tcttaacagt ggctttgcca gcactggcat ttcgagcttt catgcaagat
      421 atcaatacag aattactgat gcaaggaatc aatgtcttga tttggggatt agttatttat
      481 attattctta ttctagtttc aaaacctttt ttcttaagct ataaagggga taagcaaaca
      541 acgttgcgtg tcctgacgat ctttggttct acgacctttt tcggaacgcc tatcgtcagt
      601 gcgatttatg gtcctgtcgg cgtgatgtat tcctcaattt tcaatattgg ctaccgaatc
      661 tttttgtatt cttatggata cataaaaatg agtggcttga agatggaagc taaaaatatc
      721 aaagcgatgt tcgtcaatcc aatcattatc gctacttttg ccggcctttt catttggctg
      781 ttccaagggt atctgccaca agtgtcagtt acaggtgcag aaggagagat aagccaagta
      841 gcgtttttgc gaattgacca gactgcaccg tggctatttc agccgatgga ttatttagct
      901 ggtttaagtt caccattggc gtggctagca atcggcgcaa cattaggtga agtaagcttc
      961 aaaaaagctg catctgaaaa aacttcatgg tattacagtc tagtcaaagt ggtatttgta
     1021 cctgcattga atatcgtgat tctagcagtt ttgacggcaa cgaatattct accagtcaat
     1081 tttgaagcac tggcaacaat cgttatcatg atggctacac cagctgcaac agtggcagca
     1141 gcctatgcta tcagttttga tagggaggca cttttagcct ccaatgcatc cttactgtca
     1201 actatttttg ctgtggtact gacacctgta tggatcgttg tattacaaat gattcatggc
     1261 ataggtttat tttcataaga aatggaggaa gaaagtatga gaatcgcatg ttacggtgtt
     1321 cgtccgaacg agatagattt ttttgaaaaa ttgaatattt accattatga tctcagtctt
     1381 tatgaagaac tgttgacaca tgacaatatc gtgtcagcaa aggaccatga tgctgtattg
     1441 ttgaggggaa attgtatagc agatgagacc aatcttgcaa aaatgcagga atatgggatt
     1501 cgttatgttt ttacacggac tgtgggagtc aatcatatcg atctacaagc ggcagctgat
     1561 tttggtatga cagtagcccg tgtaccatcg tattcgccaa atgcgatagc agagttatct
     1621 ttgacttttg ccatgatgct tttgagaaat actgcgtata cgacgatccg aacatctttc
     1681 aaagattttc gagtggatga gcaaatgttt agtcgtgaaa tcagaaattg cacagtaggg
     1741 atcataggaa caggcaggat agggttgacg gaagctgttt tgtttaaggg actaggagcc
     1801 aaagtgatcg gctacgatat tcatcagaca gaagctgcta aaaaagtatt gacgttccac
     1861 tcgcttgaag agttattagc caaaagcgat attgtcagta ttcatgtacc tcatatccca
     1921 ggtgaaaacg atcaaatgat caatgaagga tttttagctc aaatgaaaaa aggtagcatc
     1981 ttgattaata cagcccgtgg agagcttcaa gataatgaag ctattttaag agctttgaaa
     2041 agcaatcatt tagctggttt tgcaaccgat gtttttgcaa atgaaacaga ggtttttttc
     2101 cgatccttca agccatggga gacgattcca gaccctgcta tccagcaatt agtagaaatg
     2161 taccctagag ttcttgtaac cccgcatgta ggttcaaata cagatgaggc attatcaaat
     2221 atgatttcga caagtttcga gaactttcgt gaaataatag aaactggaaa aacgaaaaat
     2281 gaggtatctc ttcctaaagc ccgtcaatta agataagaaa acatggatat tcgtcaataa
     2341 aatgtttaaa aatagtccaa gtaaacagtt gttacttctg tatacttgga ctattttgta
     2401 tgggataatt cgatgactca acagtaatct gtgagctttt tccgcccatt ctttgtcaat
     2461 tcataacagg ttagcggccg gccgatttcc aaatatttga ttctttcgtt caatatatct
     2521 tgttctacta aaaaattcaa atatttcttg acggatatac gtgacagtga gcttttttga
     2581 gccagttctt ttgttgaaaa aatagtatct tcttttagaa taaatgcact tatttttttt
     2641 aaagtcagtt ttgacagacc tttaggcaaa tcgatgaatg atggtatttc gtgaatggga
     2701 gtggtgtggt tgaatacttg atcgatcaat ttctgatcgg ctttttcagt cgtttggatt
     2761 gtctgagaga aagcaagata cttttcgatc gccagctgaa aacgttgcaa agtgaacggt
     2821 ttgatcaaat aatctaaggc accgtagcgg atcacattct ttatggtttc gatatcatct
     2881 gcagcagtga tcaaaatcac tgggatatca tttccttgct gtctaagcca agataaaaaa
     2941 tggataccac tttcgccagg catgtataca tcaagcagca gcagatctgc gtttttttgt
     3001 ctgaaatatt tttttccttc ttctacattt ctgaaacttt cgattacgtt catattaggg
     3061 atgctttcca caaaagtacg attcaattct gcaaccattg gatcatcttc gattatcagg
     3121 acatttgtca tcattttgat cttccttttt tggtaattct agatagacga ttgtaccgcc
     3181 atttgtttgt ttggaaaatt ctaaaaatcc accgtggcgt ttgacgattg aatggatgag
     3241 attcaatcca aacccacgat tgattccctt cgtcgaaaaa cctagcgtaa atattttttc
     3301 tgagatttct tctgatatcc cgacaccgtc atcgcagacg gtcacgatga atacttcagc
     3361 ttctgtgtca tagtttaaat gaatccggac ctgtccgttt ctttcatgtt tttgtagcac
     3421 ggcttctttt gcattatcaa gtaagttccc taacacttgc aaaagtgaat ggatggagtc
     3481 atccatctcc attttaggga taaaagaatc gctttctaac agcatttcaa cagattgttc
     3541 tttggcttcg tttattttgc ctaataaaaa accggcaatt gcaggtactt tgatcagact
     3601 tgagacttgg ccaatctctt ttttataatt ttgatttagc tgctggataa aatgggtgac
     3661 ttcttcatac ttcttcaaat caatcaaacc agaaatgaca tgaagtttat tcatgaattc
     3721 atgggtttga gctctcatgg agtttatata ttgtttcgtc cccccaagct cctccattaa
     3781 tttcattact tctgatcgat ttcgtaaagt tgcgactgct cctaaaaaac ggtcattgct
     3841 aaaaagaggt gtaacgctag aaatagtttc tatcccattt aaatacatgg attgagtccg
     3901 aacggtcgtt tgatgctcaa tcgtctcttt aaacaaaacg tcatatagat tatcactgat
     3961 ttttttccta cttcgaaatc caatagctgc tctgtttggt agaaaatgtt ttttgcaggt
     4021 gtattgatca agaggatagt tttatcagaa gagatggcta agattccttc atctacttca
     4081 ttttcgataa tcgttttttc acttaactgt tctgctattt cttgtggttc aagtccaagc
     4141 agtacttttt tcattttttg ggcaagaaaa acggcgccta tgatgcctac gctaagtcca
     4201 ataatcaatg aaaaaacaat cattttttgt ccatctttga cttgattgtc aatcgtgttg
     4261 tttgttaagc caacacaaac tgcaccaata atctcttgat cataataaat agggacgaaa
     4321 tagcggaagc cgaaccctaa cattccttct ttttcagaga aaaattcttg tcctccaatc
     4381 acttttttca catcttcatg acttgagaaa ggaagaccga tgtaacttgg gtctgcgtga
     4441 gaatatcgaa tgccttcagg gtccatgaca acgataaaat ctaaattcga tgcaatcatg
     4501 atttcatttg ttattccttg aatcgcatgt gtcgggtcac cagtctgcag ctttttttgg
     4561 atgagtttat cattggcaac gattttagca atgctagaga ttttatctga cacactagat
     4621 cggttcatcg aaagaataaa attcctgatc aatatggcag aaacaatcaa agaaacgaat
     4681 gtggagaaac aaacgacaag gatgatcgtg ttctggagct ttaatggttt tttcttaaaa
     4741 aaaggaaaca taggctacct cgaaagaatt tattgtgaaa attttaacat gaaaacaaaa
     4801 atttaacaaa ttgtcaacga taaacacaac cttcctataa aaaacaccac tgagtcggta
     4861 aaagaagcta tacagaattt tcaaacattg gtatgataga cgtagaaatg gaaggaggcg
     4921 tgtatatgat agggggaatc gcacttgaga cgatttattg gtatacattg ctgatttgtg
     4981 caggattggc agtcctattg attatttttg gagatgtatt cgattttgat ggcccgcttg
     5041 atccgatgct tattatccct tggttaactt tcacaagctt atttggtttt ctaggtgagc
     5101 gtttaacaga tcaatcatct ttatttttat ttattgctag tggaggcata tcgatagtgt
     5161 tggtattttt gcttaatttc tatatattga tgccgatgaa acatgccgaa tcaacgatgt
     5221 cgtcttctga aaaaactctg gaaggacaag tagctgttgt gatcacaccg atccctgtac
     5281 gaggtatggg agaaattcag ttgaaaagtg ttaccggttc cattagtcgt ccagcttgtt
     5341 tttacagccc ccaagaacag acagctgagc ggggaacgaa agtattgatc attgagatca
     5401 aggaaagaat ctgttatgtc atgccttatg aaagcatgat aaaagcttaa aggagcgtgt
     5461 gttaaatgga aataccagtt gtttttatcg cgatcgcaat cgcagctttg attttactga
     5521 tgttgctgat cgtctttgta gcgaagtacc agacagcaaa accggatgaa gcgttgatca
     5581 tcagtggaag ttatttagga agcaaaaatg tgcacattga tgaaagcaat aacaaaatca
     5641 aaattgtgcg tggaggtggc gcattcgtct tgccagtttt tcaacgttcg aatcggatca
     5701 gtctattatc gagtaaattg gacgtctcca cccctgaagt gtatacggaa caaggcgtac
     5761 cggtgatgtg tgatggtact tcgatcatca aaatcggttc atctgtagaa gagattgcta
     5821 cagcagcaga acagttttta ggcaagacaa gagaagaact ggaaaatgaa gcaagagaag
     5881 tattagaagg acacttgcgc tcgattcttg gttctatgac tgtagaagaa atctatcaaa
     5941 atcgcgataa gttcagtcaa agcgtacaag aagtcgcttc tgtagacctt gcaaaaatgg
     6001 ggttgatcat cgtttctttc actatcaaag aggtcagaga caaaaacggt tatcttgact
     6061 ctttagggaa accaagaatc gcccaagtca aaagagatgc agatatagca gaagcggaag
     6121 ctctaaaaga aacgcgtatc aaaaaagctc aagcagaaaa agaatcacaa gcagctgaat
     6181 tacagcgaca aacagagatc gcagaatcat taaaagaaaa agaactgaaa ttagcaacct
     6241 acaaacaaga acaagatgtt gctaaagcaa aagcagacca agcctacaat ttagaaagtg
     6301 cccgagcaca acaacaagta atcgaacagg aaatgcagat taaaatcgta gaacgtcaaa
     6361 aacaaatcga actggaagaa aaagaaatca cacgtcgtga aaagcaatat gattcggaag
     6421 tgaagaaaaa agcagatgcc gatcggtacg ctaaagaaca agaagcacaa gctcaaaaag
     6481 tcaaagaagt gactgaagcc gaagcagaac gattccgtgt ggaagcactg gcagaagcgg
     6541 aagccaataa gacacgttta gctggacaag cagaagccga agcagcacta gcaaaaggaa
     6601 aagcagaagc cgaagcaaaa caaaagatcg ccaatgcctt caaggaatat ggcgaagcag
     6661 ctgtcttgag tatggttatc gatatgctac cgcaattgat gcgcgaagca gcacagccgc
     6721 taggaaatat cgaaaaaatc tctgttgtcg atacaggaag cagttcagga gaaaccagtg
     6781 gagcgaaccg agtgacaaat tatgccacaa atttgctttc ttctactcaa gaaacactaa
     6841 aagcgacaac aggacttgac ttgaaggaaa tcgtagagaa tttgtcgaca cgtgggacta
     6901 ctagccaagt aaatatgtat gaagcgccaa aagaggcaga acaaaactcg atgaaggaag
     6961 aataaagtag tacacttcac cgttcaatca aaaatggagg aagacttttt aaagttcttc
     7021 tctccatttt tttattttat tgcaaaagaa aattagtcct cgctattttt cttttgtttt
     7081 tggatcttag cttctatctc ttgtaaattt gttcttagca atcgttcttt cttttggagt
     7141 tcgaccaaat cttctgatag ttcttccttc ttttctgttt caggaggacg aagaaagaaa
     7201 ttgataccga ttgcaatgaa tgtccctata aaagtatcta gtacacgttg gatagcatac
     7261 aaagcggatt cgccttgagg gatgctcaac gcaatcagca acaacgtagc tattgcggaa
     7321 atgataccgg aattattgtt aataccatct gacacgacga tcacaataat aactagaata
     7381 ggaagcaaga tcaattctac caaaaaatca ttgtgaaaat agcttttgac aaaaaaataa
     7441 atgatagcta atgtaccacc taatgtattg ccgatgatcc tagactttcc aaaagaaacg
     7501 gttgtagtca agtcctgacg caaagaaaaa acagcagata atgcagcaat catcgggatt
     7561 cctcgttgag tcaaatgaaa aaacaagata cataaaaaaa cagctaaggc acttttgatc
     7621 gtacgcatac ctagtcgaaa acggccaaat tgcatagaga ttctcctttt tggtcttttt
     7681 actatcatac ctaaactttt gtctgatagc tagtttttca ttattcaagt ataattaaaa
     7741 taaaaaaggg ggaagtaaat gcgtatagga atgcgaacag tcaaaacagt gatcagtgtc
     7801 ttcttttcga tggtcacagc gggtagctta tcgctgttgt attggccagc tgcagggatc
     7861 attgcattat taagtgtagg aaataccaag cgctctacat tgcgtacggg catgaatcga
     7921 atcgcagcct ttatattagc tacggcaaca gcactgttca gtttttttgc tgttgggtat
     7981 actatttttg gcttcagtct ttttttattc ctgttcatcc cgcttgcctc tcgcttcaaa
     8041 ttaaccgaag ggatagtagt aaattcggtt ttggtcactc attatttagt ggaggaaaac
     8101 atgtcttggc agctgatcgg caatgaagcg ggattaatgg cgattggatt agtatttgct
     8161 ttgcttgcaa atgtttacat gccagatcgt acgaagcagc tgaaggaaaa ccaaatacag
     8221 atcgaaaaag aatttcgaaa tattttgaga caaatggcag aatttctttt atcagaaaat
     8281 aaagaagatg tgcagatcaa atgcgaacat ttactgacat tcattcgcga aagccaagaa
     8341 gatgccagag aacatcaaga aaactactgg ctcagacagc cgctatacta cgaaacttac
     8401 ttctctatga gaagagcaca ggccaatgtg attaaagaca tgctggaaaa tctagagaga
     8461 atccagcaac cagcttatta tggaaaacat atctatggtt tattgattta tactgcagaa
     8521 acattttcag agtcaaatga tggcagacaa attttaacac gtattgaaga agtttatgta
     8581 ttgtatcggc aaatgcctct gccgactagt cgccctgaat tcgaggatcg agcagaattg
     8641 ttccagtttt tgcagtcttt taaaagtttt attgaaatca aggcagaatt ctcccaacaa
     8701 aaaatccaaa aatagaggtt gtgaattcag ctaatattca ggtcaaaaag ctgatttcac
     8761 aacctcttct ttaaacggtg ttctcctgtc aactcctcgg tcacaagtca caatattcaa
     8821 caaacatgag aagctgtttt ttgaaattgc tccttgtgac tcggagctga acggtaggct
     8881 cacaacctct ttcttaaacg gtgttcaaaa gctttcctct gcggtaataa gtccagccaa
     8941 acgaaaaata ggaggagcta tttttgtttg gctgttctta ttacttgatg cagaacagct
     9001 ttttcacaac cttttaaaat tacatatttt tccatagaac ttgcatttga tccaagattt
     9061 cgatgacatc ttttgtcaag aagagagagc gattgggcaa gtcaccttca atcatgtgta
     9121 ccatattctt tatttcgtaa ttcattgctt cagatgtatt cccgctttcg atgaattcct
     9181 ttgtaccatc tgtaaataag atctccgcac gatcagcacg cgggtaatca gcaatcgtca
     9241 cataaccgtt ctcaaaggca acgataccga cttttggcat ttttgcctga aaagtcaagc
     9301 tgacagcagc aagttcattt tctttgttac gcaagatagt gacggattgt tcgtccacgc
     9361 ctgtttcaaa aggaaccatt gtagaggcaa ctacttcagg ttgagagctc aaaaagaaac
     9421 gagcgaaaga tacagcatac gtaccgatat ccaacagagc tcctccagct aattctggat
     9481 tgaagaaccg gtttttaggg tctggttctt tgtaactgcc gaaaggtgct tggatcattt
     9541 ttaaagcccc cagttttcct gtatccatta ttgagcgtaa ctgctgataa agtggcatgt
     9601 tgaagattgt catcgcttct gctaagatca aattcttttc ttctgctaag cgcatagcgt
     9661 cagccagttc ttttttattc atcgtgatgg ctttttcaca tagaacgtgt ttgcctgctt
     9721 ccaatgctgc caagatatgg tcgatatgct gtctatttgg tacagcaatg tacacgatgt
     9781 cgatttcagc atcgtctaac atttcttgat agcttccgta agcttttgga atattgtaac
     9841 ggtgagcgaa gttttccgct ttttctgaag ttctggaagc aactgctgtt agttcgctcg
     9901 tctcttgatt gaagctttcg gcaaactcat gtgcgatggt accaagacca acgattcccc
     9961 attgatattt tttcatctga aaacgctcct tcatagttgg attgagtttc ttgtctgtct
    10021 attattataa caaaaatcac gaagaataaa gaggagagga cttgaaacat taaaaaaaat
    10081 gaaagcagcg atttaagagg tgctttttga tcaaaactta agtagaatag ttaaaaggag
    10141 gggataaacg tgcatcaagt atatattgat cttattatga gtgtattatt agaacagttt
    10201 gaaactgaaa aaaatttttt agatgaatac ttgctgatca gtccagaaca atggcaaaaa
    10261 tggaaagatg gcgagaaaaa tctgccatct gaagcgatgc agaaagtaaa aaatcttttc
    10321 actgattatg aatggatgct aacgcaaaag attttgcgtc aaacgattat ttttcccgaa
    10381 aaacgaaacg ttgccgttgc agagtacaag caaatcaaaa cacgcatcgc gcaaaaatgg
    10441 cttagcagca aagcagcaaa agtcgagctg atccctttga aaaataatca gcaggctggt
    10501 agataccttg acttgaaagt aagtattcaa tatgatgaat ggggctatga tgatattttg
    10561 aattttcgtc tgccagcaga tgttcaaaaa cagatcgaag gagaaaaaat cgaacttctc
    10621 gattgggtga atgaaaatct ggaagaaact tacgttcatg aggcgaatgg ggaacgtgaa
    10681 gaacaacgaa aggatttttc aagtgaataa atttttagga tttggagcag ttgtgattat
    10741 gatcgcagca atgggctatg ttatttttag cgatgatgat tcgcatgttc aagccggcaa
    10801 tcaagcagtc gaacgaacaa gcaccaaaac aactgctagt aaagaaaaga acagtcaaac
    10861 aaccagcagc aaggtaaagg acaaagaaac aaaagatcgt acgtccaaac aattgccaga
    10921 tgttaaaaca gacgattgga agctagtttt ggttggtcca gatcacaaat tagaaaaaga
    10981 aattgatgag tctactcaat tggcatcatt aagtaacgga tacttgatcg acaaacgcat
    11041 tgctccagaa tatgaagcat ttgccaaggc tgctgaagca gctggatttc cattagtgat
    11101 ggtctcagct taccggtctg tatcatccca acaacaagtt ttcgaacaaa atgtccaaga
    11161 tgtgatgagt cgtcaaggtg tatcagaaga ggaggcgaca aagattacta aagaaacgat
    11221 tacggagcca ggatacagcg aacaccacac aggtctggca gtcgatgtcg tcgatcaaaa
    11281 ctggtacaac agttatcctt ctactgtatt ggatgcaagt tacggagatc agcctggagc
    11341 taaatggatc gcagataatg ctgcgcagta tggatttatc gttcgttatc caaaaggaca
    11401 cgaagatata actaagatca catatgaacc ttggcactta cgttatgtcg gtaaagaaaa
    11461 cgctgagtat atcaccaaac accaattgac gctagaagaa tatctgaatg aattaaatga
    11521 aaagtaggaa ttgatcatgg cgaaaaaaaa gtggaaaaag caaaagcgca agaatatccg
    11581 ttggccagca gtggttgccg gtgtagcagt gatactctta gcctttgttt tttccttgaa
    11641 gaatctgtct tctcctttta ctgataatca gcaagaaaat gaagcgcaat cccatcagca
    11701 atttattgaa cggcttgttc cgcatgccca agaactacaa gatggttatg gagtgcttcc
    11761 tagtatcatt ttaggacaag ctatattaga atcaaattgg ggaaaaagta ccttggctag
    11821 caaatacaat aatcttttcg ggatcaaggc ttatggggat cagaagaaag taagcctgga
    11881 aacaaaggaa tttgttaacg aagaatggat aactatccaa ggagacttca aagtgtatga
    11941 ttcatgggaa cagtccatgg atgaccatac acaactgttc gtccaaggag tagattggaa
    12001 tcctgcgctg tatgaaaaag tgattacggc caccaactat caggaagccg cacaagcatt
    12061 gcaagatgca ggttatgcga cagaccccgg ttatgcgcaa aaaatcatcc aggtcatcga
    12121 gacgtatcaa ttgaatcagt atgaccggag atagcaaagg agaagtggct gatggcagaa
    12181 caatttacgc cagaaatcat gacggaattg agaaaagata tcgtaagagt accggaaatc
    12241 attttagaag caagcgggat caagatattt ggaaaattga tccgttcgat catctttact
    12301 acggatattg cgatcatacg taatacaaat gcgaatgcag taattgctgt gtatcctttt
    12361 acacctcatc cagcgattac taaaagcatt attgaggcag ctgacattcc agttttctcc
    12421 ggtgtaggtg gtggtttgac acaaggtgct cgttcttcct acatgagcat gttcgcagaa
    12481 gcgcaaggtt cgttaggggt cgttttgaac ggtcctacgc ctttagagac agtaaaagaa
    12541 gtttgtcgag tagttgatat tccagttatc agtacggtaa cgtcgaaata tacagaaata
    12601 gatgaaaagt tagcagctgg tatttcgatt atcaatatca gtgcaggtaa agaaactgca
    12661 gaagcagtac gccattttcg taaaaaatat cctgaacttc ctatcattgc gacaggtggt
    12721 ccaacggaag aaagtattgc tgagaccatt caagcaggag caaatgccat cacatatacg
    12781 ccaccaagta gcggagagct ttttagtcgt aaaatggaaa aatatcggga aactgagaaa
    12841 aagaatcatg aataacaggt gagaatcaaa agacgaggaa gagcagatag tggctcttcc
    12901 tcgtcttttg tactccagta ctatttgttc agaattcaaa aaaaagagaa atttttttgt
    12961 ttttttacct gtaatgtaca taagaagagt taaaaccttt tgttattatt agcattctaa
    13021 caaaaaaatg tcttgattta ttgaagcgct ttctatagaa tgaaaaacga ataaaaacta
    13081 aaaaaggcac ccgacaattt agtagcagct aaattgtcgg ggcttgaaaa gtcagcggga
    13141 actgaccaat caagttgcca tagtcaatgc ttgtgcatcg acgtgtatat tgtacctaat
    13201 ttcatacaga attactagtt atttttctgt tttttaggga agagcgcaca cgaagaagca
    13261 tgcttattta gctatgtcaa ggatattggg cagttgtctg atatcctttt ttctttgcgt
    13321 aattatcctc ccatcattga agcaagaagt gtttttagcg atgaaagaag aatcagcact
    13381 atctaatttt tcttgaaagt attgagttgt tcatcctagg cagaacgata aggcaagtct
    13441 tggtttttat tccccttgaa aaagatcgtt taataaatat gttctgtata aaaatacagt
    13501 atattgaaaa ataacaatgg aagtagaggt gcagagaatg aagaaaagaa tgagaatcat
    13561 cttagcttta agtgttatgt tattcttctt gacggcttgt gggcaagaag atgacaaaaa
    13621 aatcacgctg aacatggctt ggtggggttc gcaagtccga cacgatgcaa cagtaaaagt
    13681 aatcgagctt tatgaagaaa aaaatcccca tgtgacgatc gattatgaat tttatgatta
    13741 tgaaggatat tacacaaaat taggtacact agcagcatca gatgatatct gggacatttt
    13801 ccaactgaac aatcaatttc ctcaatacat caatcagatt gaaccattag atgaatatgt
    13861 ggagcaaggg ataattgata tttctaatgc agatgaatcc tatttagcaa cgacgactta
    13921 cgacgggcaa ttagttggac tgtctaacgg ggtgaattcg tttgcgattg cttacaataa
    13981 aaatatattt gaacaattaa atatccctga accagcttca aattggacat gggatgaatt
    14041 tgaacaaatc agctatcaaa tcactgaaga attaggaatc tatgctattt caagattcga
    14101 agattttata gctggctgta ttattcaaat accacaagtt gagaaaggat tgaattttta
    14161 taatcgggaa gatctatcta acagcttggg atttgaaaat ccagactatc taacagattt
    14221 tttccagctg cgtaaaaatc tggtaaacaa aggggcccat ccagaaccag gtggtggagc
    14281 tgcaagtacg acggatctgt cttttcaggc ggttagggat agagaagcgg caatggtgtt
    14341 tctatcaagt aaccagttga cagaaatatt gtcaggggct cctgaagata tggagattca
    14401 gttgattaat ccacctcgca gaaaagcaga tggagaatct ggtatccctt tacgttcttc
    14461 gcaaatgctg agtatggcaa aaagctcagc ccataaagaa gaagctgcta agtttattga
    14521 tttctttcaa aacagtgaag aagccaatga aattttaaaa ggagaacgtg gtgtaccaat
    14581 catgtcgaat attcgagaac agctcgctcg tgcagatgat gcaactttgc aagcgacatt
    14641 tgattattta gaaatgattt ccgatatgga caacggcgaa gtgaatgtct ttgatagtgc
    14701 tttgaatccg gaaattcaag accaatacaa tcttttagtt gaaaaagtca tttatgaaga
    14761 agtaacagca gaagaagcag cagagagtct ttatgagttt gcgtcaaaca ttctaggata
    14821 gcagcaggag gaaggcatga aaaaagaaaa actaaaacgg ttcttggatc aagacaatgt
    14881 ggtcggttac gtatttgctt ctccattcat cctaggattt ctattgataa cagtgatacc
    14941 gatgatcttg tcactttatt attcgttcac cgattatcgt ttgggaaatc cagtctcatg
    15001 gatcggcttg gataattata taaagatgct gagtgatgcc cgttttttga actccatccg
    15061 agtcactttt ctctatgtat ttgcatctgt acctgtgaaa ctgatctttg gtctattgat
    15121 tgcttatctt ttaacgagga atatcaaagg aacgactttc tttcgttctt tgtattatgt
    15181 gcctagtttg atcggtggca gtatttctat cgctctagtt tggcgggagt tgttttctaa
    15241 aaacgggtta gtgaatattt tcctggaacg attaggcgca cctgcgcttt cctggtttag
    15301 cgatcaaaaa ctggtcatga tccctcttgt tttgatgtct gcttggcaat tcggttcggc
    15361 aatgatcatc tttgctgcag gtatcaaaga gatcccaggc tcgtattatg aagcggcaga
    15421 gatcgatgga gcgaacaaat ggcagacgtt ttacaagatc acgttacctc ttctttcgcc
    15481 gatcattttg tataacttgg ttatgcagac aatcgcggcg tttatgactt ttacgcaggc
    15541 atttatcatt acccaaggtg gtccgaatga tgccacgaac ttttatgctc tttatgtgta
    15601 taaccaagct ttttctttta attctatggg gtatgctagt gctatttcgt ggatcatgct
    15661 gttgattatg ggagctgtca cctttctgat tttcaaatca tcaaaaaaat gggtcgttgt
    15721 gtgaatgaga ggaggaagaa atgaataata cagtaacgaa atggtttcaa tacggtttta
    15781 ttttgctatt aggtctagtc atgatttatc cggtcttatg gatgatcgca ggttctttta
    15841 aaacggatca agagattatg agtggttcgc tgaatttgat tccagagact tttcaatggg
    15901 aaaattacgc aaaaggatgg gcggggtttg ctggaatttc attttttact ttctttagga
    15961 attcgtttgt catctctgca gtttcgacga tagggacagt tctgagctcg acttgtattg
    16021 cttacgcatt atcgagaatc gatttcaaag gaaaaagatt ctggttcgtc gtcatgttag
    16081 taacgatgat gattcctgca caagtgattt tgattccgca gtttattatt tacaatcggc
    16141 tgaatttggt tgggacgtat gtgccgctga ttttaccaca tttttttgga caagcatttt
    16201 tcatttacca gatcatgcaa ttcatggtca gcatccccaa agagttagat gaatcagcga
    16261 ttattgacgg atgcagcaag tatagtgtct ttaccaaaat tatttttcct ttgctgaaac
    16321 cttcgatcat cacgacgatc atcatccagt tttattggaa atgggacgac ttcatgggac
    16381 cattgattta tttaaacaag ccgagatctt acacggtatc gattgccatc aaattatttg
    16441 cagacgctgg atctagtacg acttacgcga gtatgtttgc gatgtctacg ttgtcgctgc
    16501 taccggtttt tctgattttc ttattcttca ataaatatct tgtccagggg atcagtacaa
    16561 gcggtctgaa gggctgaata tgaaaaagcc aatagaagag atgtttcttt acaagctcaa
    16621 ctactatgtc tgtcggattt ttttaaccag tcttatcagt aatgctcttt tcgctttagt
    16681 tctaggatgt ttgttcactt taggattagt gctgtctgct cgtgttgtct atctgattta
    16741 ttttttgatg atgtatcctt cttattatct atctgtccat tacttggcag aaaaaaaggt
    16801 atgttggagg aaaggaaaaa tcaaacggat gtgtttcatc attacgttgt ttcagctgtt
    16861 tgtcattatt tttgcagttg attggtattt attagtggga aagattggag cttggtatct
    16921 gattcctttt ctattgtgtc tgttgctttt tgtatcccat agttttttta gtacgctaat
    16981 tgatatctgc aaagaagata aagcagatag tcttgtttat ttgatcaaaa ggaatatctg
    17041 gctgttgtca aaaaacgtca aggggtttct gtggtattta tgccttttgt atggactgtt
    17101 ctggtgtata cagcatgatt ttttactcac tgcattactg tatccagggc tgccatttgt
    17161 cacagtattt tgcttaaaag aaaaggagaa tgactttaaa tgaagaaaaa atatgtacaa
    17221 gtcggacttg gtgggagagc gcgttttttt tatgaggcaa ttgcctctac gtatcatcaa
    17281 acttgtgaac tagtcggttt ttgtgatgta tctcaaacaa ggatggatta tgcaaatcgg
    17341 atacttgtga acaagtatgg acagaaaaaa gtaaagacat gtatgccatc acaatttgag
    17401 caactactgg atgacgtacg gccggctgaa gtcattatta cgtcagtaga tcgaacgcat
    17461 catgattata tcattcgtgc aatgaaaaaa ggatatgatg ttatttgcga aaaacctctg
    17521 actatcgatg aggaaaaagc tcaagaaata ataacggtcc aaaaacagac gggaagaagc
    17581 ctgcgagtca cttttaatta tcgttatgca ccgtatcaca cgaagataaa ggaactgata
    17641 gaaagtgatg tgattggtga tgtgttttct atccacttcg aatggctgtt aaatacgcaa
    17701 cacggggcag attatttcag aagatggcat cgaaataagc acaatagcgg cgggcttctt
    17761 gttcataaat ctacccatca ttttgatcta gtgaattttt ggttgaacag ccgtccccaa
    17821 aaggtatttg cattcggtgg attaaacttt tatgggatgc ataatgcgga gaaacgcgga
    17881 gtagaaatat tttacagtcg atgctatgga agcgaactag ctaaagctga tccatttgct
    17941 atagacctgt cagccaatga ggaattgcga gaaatgtatt tagaagcaga aaaagacagt
    18001 ggatatattc gtgaccgcag tgtattttcc gatgatatct ctattgaaga tacactaggc
    18061 gtaacggtca aatatgaaac tggtgcgatt ttgacgtatt cgctaaacgc gtatatgccg
    18121 tgggaaggat tcaatgtttc tttcaatggc agcaaaggac ggatcgaaat gaaagtgatc
    18181 gaaaagtctt acatcaatgc aggtggagat aaaaaggatg aaggagcagc cgttcttcag
    18241 tccatccatg tctatccgat gttcggtgag ccatatgagg taatcgtcga acaagaagcg
    18301 ggcggacatg gcggaggaga tccgcgttta ttagatgatc tatttggtga agaaaaagaa
    18361 gaagatccgt ggaatcgggc agcaactcac gtagatggta ttttgtcgat tttgacagga
    18421 atcgcagcaa atcattctat tgcttcagga aaagcagtag tgattgacga gcttgtcagc
    18481 ttaaaagaat aagaatagat ttacggaaat tacttcccgt agtttataaa atcttgcctt
    18541 attgccgata ggctgtcttt tgaacactat ttattcggaa aaaggggcta tgacatgctt
    18601 tttgtcatgc cttcttttta tgtgggctgc ttttttagat aggagaaaat aaaaataact
    18661 atttaaaccc gaacaaaaag gaataatgca ttaaaaatca ttagatttta caaaaaaata
    18721 agtaaaccac gttgtcagtt tcagaaagta gtgttagact gttttcaata tttgaaacaa
    18781 cattttttat tcaaatatgg caaactgcct tcacgtgcaa aacagttgca agaaaatgaa
    18841 tttacactat tattagtttt acatacctac ttatatatcg tcataatatg gatgacagtt
    18901 tctagccagt accgtaaatg ctggactata agtaaaagat tggctatttc acccttcttt
    18961 tcttatgata aagtggaggg tgtttttctt taacagaaac atagtaggtt tttgcacaaa
    19021 agcggttatt tcggtattaa taaatgataa aggagcaaat aaagtgaaag aattagttga
    19081 acgtattcaa aaagacggac gtatattagg cgagggcgta ttaaaagtcg acagcttcgt
    19141 cactcaccaa gtagaccctg tattgatgga acaaatggga aaacggtttg cagaagtatt
    19201 taaagaacaa ggaatcacga aagttgtgac cattgaagct tctgggatcg caccagcttt
    19261 atttgctgca agagaattag atgttccaat gatcttcgct agaaaagcaa aaagtttgac
    19321 gatggatgaa gaattattga cagcttctgt ttattctttt acgaaacaag tgacaagtac
    19381 gatttctatt tctcgtaaat ttttatcttc agaagacaaa gtattgatta tcgacgattt
    19441 cttggcaaac ggacaagcgg caaaaggatt gatcgaatta tgccagcaag ctggagcgca
    19501 agtagaagga atcgggatcg tcatcgaaaa gtctttccaa gatggacgtc agttacttga
    19561 agaaatggga ttgagagtcg tttctcttgc gcgtattgct tccttgacga atggacaagt
    19621 tgagtttctt gaggaggacg cataatcgtg gaaaaagaaa cacaaaatgg aaaagctgcg
    19681 gttttagggc tgcagcatct gctagcgatg tatgcaggag cagtagcggt gcctcttttg
    19741 atcggtacag gactaggctt taatcaagaa cagatgactt atttgatttc aattgatatc
    19801 tttatgtgtg gattagcgac attattgcaa ttgacagtta accgattttt cggaattggc
    19861 ttgcctgtcg ttttaggatg tgcgatccaa gcagtagctc cactgatctt gatcggaacc
    19921 aatgaaggag taggagctat ctacggatct attatcgctt ctgggatctt tgttgtgtta
    19981 gtttctggtg tcttttctaa aattaaaaaa ctattccctc ctatagtaac aggaacggtt
    20041 atcaccgtta ttggtttgac tttgattcct gtagcaatcg agaaaatggg tggaggtaat
    20101 gcaacagcag ctgattttgg tgacaaaaca aatctgctac ttgcatttgt gacgattctc
    20161 ctaattgtag gcgtgcaaat gctggcaaaa gggttcattc gttcaatcgc ggtattgatt
    20221 ggtttagtcg gaggaagcat cttagctgct ttcatgggaa tgattgatct gagcgcgatt
    20281 ggagatgcgc cgttgttcca tgttccacaa cccttttatt ttggtaaacc aactttcgac
    20341 gtatggtcga ttttactaat gatcctcatt tccatggtca gcatggtaga atcaacaggt
    20401 gtatattttg cacttggtga cattactggg aaaaatgttg gagaagaaga attgaaaaag
    20461 ggatatcgtg cagaaggact tgccgttatc ttaggcggta ttttcaatac attcccttat
    20521 actggctttt ctcaaaatgt cggattggtt caactttcgg gaatcaaaac aagaaaaccc
    20581 atctatttct ctgcattctt cttgattgtt ttaggattat tccctaaaat cggtgcgtta
    20641 gcacaaatca tccctgagcc ggtacttggt ggaggaatgt tagtcatgtt cgggatggtg
    20701 gcagtccaag gaatccgtat gctgttggaa gttgatttca gcaatgataa aaatctattg
    20761 attgttgctg tttctgttgg atttgggctg ggtttcaatg ttacgccgac attattcagt
    20821 caaatgccgc aaacattgca aatgttcact ggaaatggca tcgtaatgag tagcattacg
    20881 gctatcatat tgaatttgat ctttaatgga ttgaaaaaag atgaagaaat attggaagaa
    20941 gccttcaaga agtaatagag caaaagaaag gttgtgaaat cagcgttttg acctgattgt
    21001 tagagaaaca aacggaaaaa tagttcctcg tattttgccg tttgtttgag ctaataccga
    21061 gggtcagctg attgaacacc gttgaaggaa gaggtcgtga gcctgccgtt catctccgag
    21121 tcacaaggaa caatttcaaa aaaaagcttc tcatgtttgt tgaatattgt tccttgtgac
    21181 cgaggagttg gcaggagaac accgtttatc cataaaaagg aatgtgacct aacttttgtc
    21241 acattccttt tttttatctt taataaacac gaacaataaa atgtttttct ttgttaacat
    21301 tcgaaatttc tttgacatca aaaaaagtga ttgttaaaat atgaatgtag aaaaactggg
    21361 aggaaaaaca atgacagcaa aaatctctgt gattatgggg agtacttcag attgggaaac
    21421 aatgaaagaa gcatgtcaaa tattggatga attcggtgtg tcttatgaaa aaaaggtcgt
    21481 ttctgctcat cgaaccccag atttgatgtt tgaatatgca caaaacgctc gaaaaaaagg
    21541 aatcaaaatc attattgcag gagcaggggg agccgcgcat ctgccgggta tggtcgcatc
    21601 aaaaacaact ttgccggtta tcggtgtacc ggtccaatca cgaacattaa atggtttgga
    21661 ttcgcttctt tcgattgtcc aaatgcctgg aggagtacct gtagctacta cagcaatcgg
    21721 aaaagcggga gcaattaatg ctggactact tgcgatacag atgctttcca tgtatgattt
    21781 agaattggag gctaaattgg ctgaaagacg ttcaatgttg gctaaaactg ttatagaaag
    21841 tagtgatcaa cttggttaaa cctttgttgc ctggttcaac gatcgggatc gtcggtggcg
    21901 gtcaattagg tcgtatgatg gcgattagtg caaaagaaat gggctttaaa gtaggtgtgc
    21961 tggatcctgt gagcgattgt ccagccgcac aagttgcaga ttggcacatt gaaagtgtct
    22021 atgatgacac ctttgcgctg aaagagcttg ccagaagaac agatgtcatt acctatgaat
    22081 tcgaaaacgt cagtgtagag gcgttaaatg cgattttacc catgtcattt attcctcaag
    22141 ggacagactt gcttgcgatt acgcaagacc gcctgttaga aaaatctttt ttggaaacga
    22201 ataacatcgt gattgctcct tatgcaacga tcgtcagtcc gacggatatc caagatgcga
    22261 ttgacgggat cggctatcct tgtgttttga aaaccactcg aggcggctat gatggcaagg
    22321 ggcagtatgt tttgaaaagt cgggcggatc tagctcctgc catggacctt ttaagagaag
    22381 gaacctgtgt tttagaagca tggatcccgt ttgaaaaaga gatttcgatc atggtggcag
    22441 gaaatggtca aggagatttc acgacttttc cggtcgtgga aaacatccac cacaacaata
    22501 ttcttcatga aacgattgct ccagccgcga ttgatcagga tgtgatcgag gaggctgagc
    22561 gtattgcccg tgtgattgca gaagcagtga gcctttcagg tgttttaggg gtagaaatgt
    22621 ttttaacaaa aacaggcggg ctatatgtga atgaattagc tcctcgtcct cacaattctg
    22681 gacattattc tattgaagct tgttctatga gtcagttcga tgcccatatt cgaggtattt
    22741 gtggttggcc attaggagaa aaagtacgtt tgataagcaa tgcagtaatg gtcaatgttt
    22801 tgggagaaca actgctggaa agctatcgct tgattgagaa taagccagac tggcaattcc
    22861 atttctatgg aaaaaaacaa gcaaaaaaag gtcgcaagat gggacatatc actatcttga
    22921 cagaagacat ccagcaaacg ctggaagaaa tcaaacaaac gaatatttgg gattagagga
    22981 gaaaaaacat gttagaacgt tatacacgcc ctgaaatggg gaatatctgg acggaagaga
    23041 acaaataccg tgcgtggctc gaagtcgaga ttttagcaga tgaagcttgg gcagaacttg
    23101 gtgaaatccc gcaagaagat gtgaaaaaaa ttcgtgagca tgcatcattt gatatcgatc
    23161 ggatcttgga aatcgaaaaa ttaacacgcc atgatgtcgt tgcgtttaca cgagcggttt
    23221 ctgaaacatt gggagaagaa agaaaatggg tccattatgg tctaacaagt acggatgtcg
    23281 tagatactgc ttatggctat ctcatcaagc aagcaaatga tattttacgg gaagacttga
    23341 aacgttttac ggaaatcatt ggcgaaaaag caaaagaaca caaatataca gtgatgatgg
    23401 gtcggacaca cggtgtccat gctgaaccaa ctacttttgg attgaaactt gccacatggt
    23461 attcagaaat gaaacggaac atcgaacgat ttgaacatgc ggcaaaagga gtagaagcag
    23521 gaaaaatctc aggagcagtg ggaacgttcg caaatatccc gccatttatt gaagagtatg
    23581 tatgtaaaca attggggatc cgtccacaag aaatctctac tcaagttctc cctcgggatc
    23641 tacatgctga atatttctca gcgatggcgc ttattgctac aagtattgaa cgttttgcaa
    23701 cagagatacg cggattgcaa aaatccgaaa cacgtgaagt agaagaattt tttgcgaaag
    23761 gtcaaaaagg ttcttctgct atgccgcaca aaaggaatcc gatcggttca gaaaatatgg
    23821 ctggtctagc cagagtggtg cgcggacaca tggtcactgc ctatgaaaat gtcacattat
    23881 ggcatgaaag agatatttct cattcttcag cagaacgaat catcttgcct gataccacga
    23941 ttttattgaa ttacatgtta aatcgttttg gcaatatcgt taaaaatcta acggtctttc
    24001 ctgaaaacat gaagcggaat atgtctgcaa catttggttt gatttatagc cagcgcgtta
    24061 tgctgaaatt gatcgataag ggaatgacaa gagaagaagc ttatgatctt gttcagccaa
    24121 aaactgcgta cgcttgggac aaccaagtgc agttccgccc gctgttagaa gaagatccaa
    24181 ccatcacatc ggtattatct aaagaagaaa tagacgatgc ctttgattat catcatcatt
    24241 tgaaaaacgt tgacgtgata ttcaaacgag taggtttgga ataaagaaga gtgagttgca
    24301 aaattcaatt aaaatagaat agcaaaaata accaaaaaag aagcagatcc gttagcggtt
    24361 ctgcttcttt tagtttatta tattttctta tcaataatag gaacctgatt ttaaaagcgg
    24421 ctacctcttt accgtgcctc tttacataca aaaaatagag gaattaagcg taaatggctt
    24481 ggctattata actaaaatgc tggttatgga gatgttgcag caagttttcg agaaaagcgt
    24541 attccatctc ttgtccattg aataagatct ggatacgata atgatttttg aaacgcttct
    24601 gttcatgaat ctgactgatt gaaagttcgc ctttgtgttc tgtctgataa agaaaagtcc
    24661 ttttacggca ttcagcacag cgcttggttg ctcggcggat ttttcggaat gtataaaaac
    24721 tagtatcttt attgcataaa taaacgtctt tgatcgacag caaatcatta tatagacagg
    24781 aacgttcttc agctgttaat tctgataaaa aaagctgacc ttgttttatt gcatcttcca
    24841 tcggcaagtg cctcctcgaa cccattatcc aaatttttag ttaattctaa tataccatca
    24901 ttaagtataa atgtaaacgc ttgttgatgg tataagattt tcgtttctga taaaacacga
    24961 acattaaaag aatctaatgc cttaaatgta catatttttg ttgatttata aaaagatgat
    25021 tgctaaaatt taaagtgaaa aaacgaacaa aaaacgatgt atttgctttt aatgtaaata
    25081 aaaaggagag acgtacatgg agaagaaaga acttttgtat gaaggaaaag ccaaaaaaat
    25141 atatcttact tctgatgaga acttgatttg gatagaatat ttagatcaag caactgcgtt
    25201 gaatggcgcg aggaaagacc agataagtgg aaaaggagaa ttgaataatc aaatcacaag
    25261 tgcaattttc cgttatctga ctcaaagagg aataaaaaat cattttattg aacaattgtc
    25321 taaaaccgaa caattagcaa aaaaagtaca aattatccct ctggaagtgg ttatccgaaa
    25381 tattgcagca ggaagtttct caaaacgtct aggtgttccc gaaggtaaag aattcatcaa
    25441 accaatcatt gaattctact ataaggatga ccagttggat gatccattta tcaatgaaga
    25501 gcatatctat ttcttacaac ttgcaaagcc ggaagaaatc agtgagctga aagcccaagc
    25561 gttggctatt aatgaaattt tgaccgaatt atttgctaag gtcggtttgg ttttagtaga
    25621 tttcaagcta gaatttggcc ggtcgaatgg acaaattttg cttgcggatg aagtaacacc
    25681 ggatacttgc cgattatggg atgaacgtac gaatgaacat atggacaaag acgtttaccg
    25741 cagagatcta ggtgatttga tcccagtcta tcaagaagta tataaccgtc tatcggaact
    25801 aactgaagaa aaggagcgag tatgatgtat ttcgtaaaag tatatgtaac ctataaagat
    25861 tcagtgttag atcctcaagg ggaggcagta aaaaaagcag tccatcgtat gggatatgaa
    25921 acaatcgaag atatccgaat aggaaaatac tttgagatac aacttgctga tgcagaagaa
    25981 ccaatcgata cagtgattga aacgatttgt gacaagctgc ttgcaaatgt aaatatggaa
    26041 acataccgat atgaaatcaa aaaaatggag gaagtataac atgaaatttg cggtcatcgt
    26101 ttttccaggt tcaaattgtg acgcagatat gttatgggca gttcgcgaga tcatgggcgc
    26161 tgatgccgaa tttgtacggc atgatgagtc ctctttagaa ggatttgatg gggttttact
    26221 gccgggagga ttctcctatg gtgactattt gagatgcggt gcgattgctc ggttttctac
    26281 aatcatggaa gaagtgattc gttttgctga agaagggaaa ccagtattcg gtacatgcaa
    26341 tggattccag atattgacag aagcaggact tttgccaggt gtactgagac gaaatgagtc
    26401 tttgcatttt atttgcaaaa ctgtaccatt gaaagtcaac cccaagacgg cctttacttc
    26461 agagtatgaa gccgacgaaa taatctatct tccagttgct catggggaag gaaattattt
    26521 ctgtgacgaa gaaacacttc aagaactaaa aaaaaataat cagattgcct ttacttataa
    26581 tgacaacatc aacggcagcg tggaaaacat tgcagggatt acgaacaaag cagggaatgt
    26641 gttaggaatg atgcctcatc cagaacgtgc agtagaagac ttgctaggat cagaagatgg
    26701 gaaacggttc tttgcttcca ttttaaaaaa cttcggaaag gtgaccgtat agatgaaaac
    26761 attgaaagaa ccgacagctg aagagatcaa gaaaaaaaga atctatgccg aatggggatt
    26821 gactgatgaa gaatatcgaa tgatcgaaga agatatctta ggaagaatgc ctaattatac
    26881 ggaaactgga ctgttttctg ttatgtggag cgaacattgt tcctataaaa attctaaacc
    26941 ggttctacgc aaatttccta ctagtggacc tcatgtgttg caaggccctg gagaaggcgc
    27001 aggcatcgtc gacatcggtg atggactagc agttgtcttc aaagcagaaa gtcacaatca
    27061 tccttcagcc gtggagcctt atgaaggagc tgcgacagga gttggcggaa tcatcagaga
    27121 tattttcagc atgggggctc gtccaattgc gttgctagat tcattgaggt tcggcgaatt
    27181 agataatcca agaacgaaat atttactaga agaagtagtt gcaggtatcg gcggatacgg
    27241 caattgtatc ggcataccga ctgtaggcgg cgaaattgca tttgatcctt gttatgaagg
    27301 aaacccatta gtcaatgcaa tgtgcgtagg tttgattgaa cacaaacata tccagaaagg
    27361 gcaagccgct ggcgtcggta attcgatcat gtatgtaggt gcaaaaacag gtcgcgacgg
    27421 tatccacgga gcaacttttg cctcagaaga atttaatcaa gaagaagaac agcaacgttc
    27481 tgctgtacaa gtaggcgatc cttttatgga aaagctgctg cttgaagcgt gtttggaatt
    27541 aatcttgcat cattcggatt ctctaatagg tatacaggat atgggagcag caggacttgt
    27601 ttcatctagt gcggaaatgg cttcaaaagc tggctcagga cttatattga cattagatga
    27661 agtcccacaa agagaaactg ggatgacacc ttatgaaatg atgttatcgg aatcacaaga
    27721 acggatgttg atttgtgtta aatcaggaga ggaagaaaaa atccaagaac tatttcagaa
    27781 gtatgatcta gatgcagtca ctatcggtaa agtaacagac gacgggcaat atcggctata
    27841 tcatcaagga gaagaagtag caaatctgcc agtcgatgca ttagctgaag atgcaccagt
    27901 ttatcataaa gaaatgaaag aaccagctcg aatcgtagaa tttcagcagt tagctcctta
    27961 tcagccagtt atcgaagaac ctggacaagt attgcttgat ctgctgcagc aaccgacgat
    28021 tgcttcaaaa cgttcaatct acgaaactta tgattcacaa gtacaaacca atacagttgt
    28081 ccgtccagga agcgatgctg ctgtgatgag ggttagaggg acgaataaag cgttagctat
    28141 gaccacagac tgcaacgcgc gctatctgta tttggatcca aaaatcggag gacaaatagc
    28201 agtggcagaa gctgctagaa atattattgc tagcggtggt aagcccttgg cgatcaccga
    28261 ctgcctgaac tatggttctc ctgataaacc agaagttttt tgggaattat cgacttcagc
    28321 tgacggaatt gctgctgcgt gtgaaacgtt aggaactcct gttatttcag gaaatgtctc
    28381 tttatataat gaaacggatg gtcaagcaat ctatccaaca ccaatgattg gtatggtcgg
    28441 attgattgag gatcataaac atatcactac tcaggaattc aaaaaatcag gggatctaat
    28501 ctatatatta ggtaagacgt ttgcagattt tgatggcagt gaattacaaa agatgcagct
    28561 tggaagaatc gaaggtgtga tccgaaactt tgatctatcc attgaaaaga gaaaccaaga
    28621 gttagtattg acagccatcc aaaacggatt gattgaaagt gctcatgact gttcagaagg
    28681 tggcttggca attgcactgg cagaatcagc tttcaaacat cagctaggga tatctgtaca
    28741 gtttgaattg tcctctgctc aattatttgc agaaactcaa tcaagatttg tgttgacagt
    28801 cgcaccggaa aataagacac gattcgaaga aatgatggga gatgctgctg ttttagcagg
    28861 taaggtgacg gatgaagcga taatcgaaat ttcagcaact gacggtcaga tcaaaataga
    28921 aactgcagta gcaagaaagt gctgggagga tgcaatcgta tgtcttatga agtgaagagt
    28981 ttaaatgaag aatgcgggat cttcggtgtt tggggtcatc cagacgccgc tagtgtggca
    29041 tacttcgggc tccatagtct tcagcatcga ggacaagaag gtgcaggtat cgtgtccaat
    29101 gatcgaggaa agcttaaggg gcatcgagat ttggggctgc tttctgaggt attcaaagat
    29161 caaagaaaat tgcagcagtt aacaggagaa gctgcaatcg gacatgtacg ttatgcaaca
    29221 gcaggcaatg gaagtgtgga caatattcag ccttttctat tcaaatttca tgatcagtcg
    29281 atcggcttag cgcataatgg taacttgatc aatgctcgtt cccttagaaa agagttagag
    29341 gaaaatgggg cgatcttcca ttctaactcc gatacggaga tattgatgca tttgatccga
    29401 cgaagtgaag aaacagattt tttaaataaa ttaaaaagtg ctttgaatga agtcaaaggt
    29461 ggctttgcct atttattaat gacagaaacg gcaatgattg ccgctttgga cccaaatggt
    29521 tttcgtccat tagcaatcgg acaaatgaaa aacggagcat acgtgattgc ctcggaaact
    29581 tgtgcattag aagttattgg ggcacgtttt ataagagatg tccagcctgg tgagatagtg
    29641 atcatcaatg acgaaggaat ccagattgat tgctttacga aggacacgca gctttctatt
    29701 tgttcgatgg aatatatcta ttttgccaga ccagattcaa acatcgcagg gatcaatgtg
    29761 catactgcac ggaaaaatat gggacggaat ttagcgaaag aatcgccagt aaaagcagat
    29821 atggtcgttg gcgtacctaa ttcttctttg tcagccgcaa gcggttatgc ggaagctagt
    29881 ggaatccctt atgaaatcgg attagtaaaa aatcaataca ttgcccgaac atttatccag
    29941 ccaacgcctg agctaagaga gcaaggtgtt cgaatgaaat tatctgctgt acgaggagta
    30001 gtggaaggta aaaaggtgat tatggtcgat gattcaattg ttcggggtac gacaagcaga
    30061 cggatcgtcc atcttttgaa agaagcaggg gcaaaagaag tccatgtgag gattgcttct
    30121 cctcctttga aatatccatg tttttacggg attgatattc aaacgcgtaa agaactcatt
    30181 gcggcaaatc acacgattga tgaaatcaaa gaatgtatcg gtgcagattc tttaggtttt
    30241 ttaagtgaag agggtctgat cgaatcgatc ggtctggaaa aagatgctcc gtattcagga
    30301 ttgtgtatgg cttatttcaa cggagattat ccgacgccgt tatatgacta tgaagaaaaa
    30361 tatcaggaat cactaaaaga aaaagtatcg ttcttttaaa agcagaccaa gaagggagta
    30421 tatgaattca atggcaaatg catacgcaaa agctggcgta gatgtcgaag ctggatatga
    30481 agtagtagaa cggatcaaga agcatgtcaa aaaaacggaa cgtttaggta tgatgggcgc
    30541 tataggagga ttcggcggtt gttttgattt atcggtcttt caattaaaag agccagtcct
    30601 tgtctcgggg accgatggcg tggggacgaa attagcagtg gcaatcgaag cagacaaaca
    30661 cgatacaatc gggatcgact gcgtagcgat gtgtgtcaat gatatcttag cacaaggcgc
    30721 agagccgtta tatttcttag actacttagc aacggggaaa aatgatccgt tacgtttgga
    30781 aaatgtagta aaaggtgtag cagatggatg tgttcaagga aatatggcgc tgattggcgg
    30841 agaaacagct gaaatgcctg gtatgtactc aggtaatgat tatgatctag ccggatttgc
    30901 tgtagggata gctgaaaaat ctcaattatt gacaggagaa acgatcaacc caggagatgt
    30961 gttgcttgga atagcatcta gcgggattca ttcaaatggg tactctcttg ttcgcaaaat
    31021 tttctttgag cagcagcagt tttctttatc atcaaaactg ccagaattga aaaaaacact
    31081 tggcgaagaa ttgcttgagc caacgaaaat ctatgtttct tccttgcttc cgctgatcaa
    31141 agaaaagaaa ataaaaggag ctgcacatat cactggtgga gggtttgtag aaaatatccc
    31201 gcgaatgtta ccagaatcta tggctgcaca aatcaaactt ggctcatggc cgattcttcc
    31261 aatattcggc tgtttacaaa aatatggtga aattcctgag atggagatgt atgaaatctt
    31321 caatatgggc atcggtatgg tcctggcagt cgaagaatcg aaagtaaaag aaatagtaca
    31381 cgaaattgag caagctggcg aaaaagttta tgaaatcggg aaagtgatcg ccaaagaaaa
    31441 acatcgtgtg gtgtttatag gagaagaacg atgagaatcg ctgtttttgc ttctggaaac
    31501 ggaagcaact ttcaagcgct agccgattat ctatcgaaaa aaggattgga atcttcgatt
    31561 gactggttgt tttgtgatca gcctgaagca tatgttttga aacgtgcaac tgcgttgagt
    31621 gtaccggcag attgtttttc acctaaagaa tttgattcaa aaaaagagta tgaagaagca
    31681 attttgcata aattgaaaga aaaaaagatc gatttgatcg tattagctgg atatatgcga
    31741 atcattggac cggtattgct gaaaaattat gataaaagaa tcatcaatat ccatccgtct
    31801 cttttacctg ccttccctgg tttgcatggc atacgtgatg cctttgaagc tggagtaaaa
    31861 gaaacgggtg tcacaattca ttatatcgac caaggtgtag atactggacc aatcatccgg
    31921 caggaaaaag tgagaattga acaggaggac acgttcgatt ctttagaaga aaaaatccat
    31981 agagtagagc atcgaatcta tccagaagtg attagtgaaa ttattgaaaa tggaggctat
    32041 ctgaaatgac aagagcattg atcagtgtat cagataaaac tgggattgta gcattcgccc
    32101 aaggtttgat tgaacaagga gtagaaatca tttcaacagg aggaacaaag catgcgttgg
    32161 ataaagctgg gatcaaaacg ctttcgatcg aagaagtgac agggtttcct gaaatgatgg
    32221 atggccgtgt caaaacactt catcctaaaa tccatggtgg tcttttagga agacgcgatc
    32281 tccctagcca tatggaggca atggaaacgg aaaatatcca accaatcgac tttgtttgtg
    32341 tcaatttata tcctttcaaa gaaacgatta tgaaaccaga tgtcgaaata gcagaagcta
    32401 ttgaaaacat tgatatcggt ggtcctagta tgctccgtag tgcagcaaaa aaccatgaat
    32461 ttgtcacctc tgttgttgat ccatctgact atgaagaagt actttcagaa ttacgtcagt
    32521 atgggcatac ttcactttct ttcagacaaa aactagcggc aaaagtcttt cgtcatactg
    32581 cggcatatga tgcactgatc gctcaatact taacggattg ggtggaagaa aaagaaccgg
    32641 aaaaattgac acttacgtat gaacgaaaac aaacgcttcg ttacggtgaa aatagccatc
    32701 aagccgctgc cttttatcag tccgctcttc tggaaaaata ttcgatcgca gcagcaaaac
    32761 aactccatgg gaaagaactt tcttataata atatccgaga tgcagatgct gcgctacgga
    32821 tcatgaagga atatgacgag ccaacggtag tcgccttgaa acacatgaat ccttgtggta
    32881 ttgggacagc atctacgatt ttagaagcgt gggaagcagc gtatgaagca gatcctgttt
    32941 caatctttgg tgggatcatc gttttgaatc gagaagtaga tctgccaaca gcagaacaga
    33001 tgcataagct gtttctagaa atcatcattg ccccttctta tacacaagaa gctttggaat
    33061 tactgcaaaa aaagaaaaac atccgattac tgacagtaga ctttgcgcag gaagaaaatc
    33121 aaaatcgaga agaaacggtc tcagtcttag gtggacttct tgtacaagat caagatctgg
    33181 caatagaaaa tgaagaagag tggaaagtcg tgacaaaacg taagccgact ccagcagaag
    33241 caaaagcatt agcgtttgct tggagagctg tcaaacatgt gaaatctaat gcgatcgtac
    33301 tggcaaacga acgtcagaca gtaggaatcg gagccgggca gatgaatcga gtcggttcag
    33361 taaaaattgc gattgaacaa gcgcaagaga aaatggaagg tgcagtttta gctagcgatg
    33421 cttattttcc aatggatgat tcggttgaat atgcagccaa acatggtata aaagcaatca
    33481 ttcagccagg aggaagcatc aaagaccaag attctattga tatggcgaat aaatacgatc
    33541 tagcaatggt ctttactgat gttcggcatt ttagacatta gagaggagtc ggataaatga
    33601 acattttggt gatcggtgca ggtggtcgtg aacatgcaat aagtaaaaaa cttttagcca
    33661 gtccgaaggt ggatacggtg tattgtgcgc caggaaatcc ggggatgaca aaagatggta
    33721 tcaattgtgt cgctatcagt gagcgagatc attcagcgtt aatccatttt gttaagaaag
    33781 aggctattga ttggagtatc gttggtcctg aagttccttt gttaaatggg atcgtcgatg
    33841 attttatggc ggaaggattg aaaatcttcg gtccgacaaa agcagcagct ctgatcgaag
    33901 gttcgaaaag ttttgctaaa caattaatgg atacttatca aatcccgaca gctaaatcca
    33961 gaagttttga atgttacgaa aaagcagcag cgtatatcaa agaaaatggt gcgccaatcg
    34021 tagtgaaagc ggacggctta gcagctggga aaggtgtagt cgtggctacc acagtgaagg
    34081 aagcgctgga tgcggcagaa caaatgttga accagcatcg atttggggat agtagcaaaa
    34141 aaatcgtcgt agaagagttt ttggcaggag aagaattctc ccttttggcg tttgtccgta
    34201 ataccaaggt gtatccgatg gtcatttcgc aagatcataa gcgggcattt gataacgata
    34261 aagggccaaa tacaggcgga atgggtgctt attcaccagt accgcaaatt tcaaaaaaga
    34321 tgattgaaaa agctgtggaa gaagttttaa aaccagcggc tttgggaatg aaagaactag
    34381 gacgctcttt cacgggtgtt ttatatgcgg gtttgattgc tacgaaggaa ggaccaaaag
    34441 tgatcgaatt caatgcgcgt ttcggtgatc ctgaaacgca agtcgttctt tctcggttga
    34501 agagtgactt tgcgcaagta atcgatgatt tattagagaa tcgtacagta gagttaaagt
    34561 ggcagcaaga aggatacaat gtaggcgttg tggttgcagc tgccggttac cccgaagaat
    34621 atgagacagg aatggttcta ccagattttc tggaagaaga gctttctgtt tactatgctg
    34681 gagtttcctc aaataacggc aaactagttg gagcaggagg acgtctttat ttagtagaag
    34741 catacggtga gacgatcaaa gaagcacaga aaaaaattta caccgcgtta atggataaaa
    34801 cgacagatgg aacattttat cgtacagata ttggagaaaa agctgccaat agcgaactga
    34861 tcgtgaagta aatcagctgc ttccatttat aaaaaataca acaaacataa tcggaagcgc
    34921 cgattttagt gaagcctttt cataaagagt gtggtacact tttgttgtgt atataaataa
    34981 ggaggagttc agatgaaaaa aattcaatta ggtacttctg atcagaaagc agctgcagtg
    35041 atcttaggct gtatgcgtat caacaatgcg gaagatccag taaaagtgat tgagacagct
    35101 tatgaaaacg gcattgattt ttttgaccat gcagatattt atggaaacgg tgaatgtgaa
    35161 gaaatctttg cagatgctct agcaaaaaca tcaatcaaac gagaagatct ttttattcaa
    35221 acaaaatgtg gaatcgttcc aggtgtgatg tttgattttt ctaaaaaaca tatcattgaa
    35281 tctgtagaaa aaagtttgac ccgtctgaaa atggattatg tggatgcttt acttcttcat
    35341 cgtccagata cattggtaga accagaggaa gtagctgaag cgtttgatga attggaacgg
    35401 tcaggaaaag ttcgttattt tggcgtcagc aatcaaaaac caatgcaaat cgaattgctg
    35461 aaaaaatatg ttcgtcaacc attagtagct aatcagctgc aatttggctt gaaacatact
    35521 ggaatgatcg atcaagggat tcatgtcaat atgacagatg aagcaagtat cgatcatgac
    35581 ggtagtgtac ttgattattc ccgattgcat gatatgacga tccaagcatg gtcaccatac
    35641 cagtatggat tttttgaagg tgtatttatc gggaacgaaa aattccctga attaaaccaa
    35701 acattagaag aactagcagc taaatatcaa acgacaccaa ctggcttggc ttctgcttgg
    35761 attttacgcc atccagccaa tatgcaagtg atcgccggta cgatgaacgt agggcgaatc
    35821 aaggaaatcg ctcaagcttc agaaattaat atgtctcggg aagattggta cgaattgtac
    35881 cgtgctgctg gaaacatttt accttaaaga ttgtcataag caggtcaaaa gggctataaa
    35941 ttaaaaagac agaataactt gaaagctgtt ttcagcttcg agatattctg tcttttttta
    36001 ttgcaaatgg aaagagtatc attgtacgga tttcgtttat tagttatttt tgtttttaag
    36061 gaaaagctgt gtccgatatt cttttggaga aatcccttgt tttttcttaa ataaataact
    36121 gaaatagtta gggtcattat aaccaatttc aaaagcaata tctgaaatac gatagtctga
    36181 ttgctgcaat aatttttttg ctaattcgat tctttgttct gtcagataat cgatgaatgt
    36241 ttggttaaac gattgagaaa aaatcgtact gaaatgagag ggacttaatg caacttgttg
    36301 agcgacccaa gttaaggaca tatctggatc ggtaaaattt tctttgataa aatccaatgc
    36361 atggttcaaa attggctgat atttgttcct tgaaggctgt gagggcagag cagttaagaa
    36421 agaaatgaac atataaactg tcgaacggta aagcgagtcg tcggcgctga ttgctaagcg
    36481 ttgactggtg gatgtgcaat gaaccatttc ttgcgggatt ttcttttctt tcaggcagac
    36541 atgctggagt agcttagtca agacaaataa acgatataat cgtgttcgag ttggtgtgcc
    36601 ttgtggtttc gtcaagtgtt cgatgtactt agatacttcg tttttcgata atgaagacaa
    36661 atcaagtgag aggtcaaagt aaaagacaga atcaactgga agtttcgctt cttgaatcaa
    36721 atcctcatag ctgataattt gttctttaag ggaactggcg gtttcaagta tcatctgcgt
    36781 gatctcaaaa gatgcaggta attcgctgat tctttctgcg acaggaccaa tggcgacaga
    36841 aaaattattt ttttgtccct tttctaattc atggaccaac gtttgggcta cctgataact
    36901 ggtctcgatc acattttctt caagagaatc aactattaaa aatttgatga atcgagagga
    36961 aacagcagag aagatcactt gttgattctc cctaaataaa aacttcaaat aatcactgag
    37021 atgagcgtaa tcttcaaagt ctgtactgac ttggtttgct gctaataata cggtcatttt
    37081 tttccctgct aaagagcgat tgaaagattc agcaagtttc aatgtttcac tgatcgtaag
    37141 tgagcctttg aacaaaccgt tcaagaaatg attttttttc aattcgaaaa caagatcaga
    37201 agaagtgtgc gtttcttttt gctgcaaatc taaagcagtt actgcttttt ctattgcttg
    37261 tttcaattcg ctacttttaa tcggtttaag cagataatca tctgcctgta cctggattgc
    37321 tcctttcata taatcgaaat cgtcgaatcc actaataaat atgagacgag tccaaggaag
    37381 tagtttcctt gcttcttttg aaaaagtcaa cccgtccatg aaaggcattt ggatatcagt
    37441 cagaatgatg tcgggctgta agtcgataat tgaagacagt gccatctcac catctccagc
    37501 ttcgccgaca taagtgattg gataataaga accaaggaca gttatttgtt cccgcaagtt
    37561 attgcgaatg aggtattcgt cttcgatgat aaaaacttta tacatgtttg tttcctccaa
    37621 ttgttttggg agatagaggg atcatcagtg tgacagttgt tccttctcgg tatttgctgt
    37681 caatcgtgat aggtttttga tcatttccgt aataaagaag gagacgcttg tttacgttgt
    37741 aaagtccgta gccgatactg aaatctgaat cgatcccttt ggctaactct ttacgtattt
    37801 ctgccagttt ttctgcaggg atgccaatcc cgttgtctat aactttgaat tggatcatct
    37861 catcaatttt gcatgtggta atacgaataa atcctttgtg acggacgtac ttcgttccat
    37921 ggtatacagc attttcaatc aatggctgca agatcatttt taaaatagaa acaggaaaaa
    37981 gtgtttctgg tatatcgatc ttatagtcaa gcatatggcc gtatcttatt tttaagatga
    38041 ctagataatc attgatatgg ctaatttctt tttcaagagg aatccagtct tgtcctttgc
    38101 ttaaagacgt acgaaaaaag ccggaaagtg catgggtcat agtcagagct tcttcaaagc
    38161 agtcttgttc gatcaaagaa ataatggcat ccaaactgtt ataaataaaa tggggagtaa
    38221 tctgagcttg caatacacga acttcacttt gtgctaaatg gtattgtttc aaagcgttct
    38281 cccgtaaaga ctggtttaga tcttccgcca ttttattcat gctagcggta agtgtttgta
    38341 attccagtgt ttccggcagg gttaaacgaa agccaaggtt ccctgaagaa agttgttctg
    38401 acatctcgat cagctgattg atcggttctt ggacctttct ctctaaaaag cgacgattct
    38461 ttttcgcata gaaaaaaatg gtactaagaa ctccaagttc cactattgtt aatagaatga
    38521 gcgagcggac aagtgtcgta ttttttttgc ttgctaagtc gatctccaca cgaacaaaat
    38581 cttgtaagat atctgacagc agttgagtga cagaatctac ctgattgatg atctcttcat
    38641 tggtatccat aaaatctttt gccaagatat tattgatcag ctcgttttga taatcttcca
    38701 gtgtatcgat cgtacgtagc gatacatcta acgtactaat ttctttaagt gtatttgtat
    38761 tatttttgat ctctcgaata tcattcctaa gttcttctag gatattttcc tcattgaact
    38821 catctacggt tacttggcca gaaatcaagt cccacatact ttccaaaact ttttgatcaa
    38881 ccttcaaagc aattgcatct gctttttgga tatttgcgat cgtctgttga taaatcaaaa
    38941 gctgttgcga atataacagt atgctcagta gcaaagggat aacagcaaat agaagcatgg
    39001 ctttgtttgc ttgggcaaaa atctgtttta tgcttaaatt ttttgtcatg atacttctcc
    39061 agtcaataat ttctggttgg gatgttagct atattctgct gggaaaagac agtctcggaa
    39121 ataaaaatat ctttaggtaa tgtttttcct gtttgaatat ttccaaaata acgagtaacg
    39181 gtattggcta cataccagcc gacatcaggt ttacactcga ctacacaatt gacgattcct
    39241 gagcgtagct tctcgatcat atcttcttgt ccatcaatag ttacaatgat caaatcttct
    39301 ccaggtttga ttgatgtttc ttttatcgca gctaaagcac cgtgagtcat ttcatcacta
    39361 tggctgtata atacatcgat ttcggataaa tcatttgttt ctaaatatcg tttcatctgg
    39421 tcttttcctt tcatccgaat aaaatcaccg acaattcggt gaacaatagt catcggaggt
    39481 ttatggtcga tggttccatc tttttttagg gttggtttac gattgattga ttccaaaaat
    39541 ccttcggagc gtagcttggt cggtgtggag ttctctgaac cagcaagttc taggattctg
    39601 atttcctgtt tctttgaatt tgtgaagtga ttgctgacaa ataaacccgc ccgatttcct
    39661 tctgctttga aactggggcc aatgtgggtg acgaaaagct cgggatcatt cgtttgaata
    39721 tgtctgtcga caagtatgac agggatccct gctcgctttg cttcttttaa tacagagtcc
    39781 cacccggatt cttgcaaagg agtaaaaatg atcatatcca ctttataggc aatgaacgtc
    39841 cgtatatctt ggatttgccg ttcctgattc atgtagccat ttcggtagag aacttggtaa
    39901 tcttcttttt caagcgcagt gataattgat tcagtatgct ttttccgcca gctactctcc
    39961 gttcctgatt gcgaaaaacc aacgactagt gggtcaggtg cttcctttgt attaggtgta
    40021 caccccatca tttggtaagc gattacaaca agggctaaaa aaaataaaac acgtttcact
    40081 ttaaatcact ccatctggat ttgttagtac tatcttatca gataaaaggg aaaatcaaag
    40141 tcaaaaggaa tcaatcgaaa aaaatccaag aaacttaaaa aaatccaaga caaaaaaagt
    40201 acacctaaaa aatttaaagt aaatcccata aaaaaatcaa tgttaacgct ttctttatta
    40261 gctatactcg gtgtatcaat tgaaatgggg gataaaaaat gaaaaacaaa tttagaaaga
    40321 ttgttgggac tatcgctatt ttgaccgcaa gcattctatt aagtgcgtgt ggcaattcag
    40381 gatctgcaga tgatagtacg gggtatgtag gaatcgctat gccgaccaaa tcagcagaaa
    40441 gatggatcgc tgatgggaac aacatggtct cggaattaga aaaactgggt tataaaacag
    40501 atcttcaata tggagaagat aaagtagaaa atcaagtagc acaaatagaa aatatgatta
    40561 caaaaggggt agatacactt gtgattgctt ctatcgatgg ttcggcttta actgatgtgt
    40621 tagctaaagc aaaagaagca gatatcaagg tgatcgccta tgatcgttta ctgatgaatt
    40681 cagaaaatgt cgattattac gcgacttttg ataattttgg agtaggtgta tcgcaagcag
    40741 cttatattga agagcactta ggattgaaag aaggaaaagg accattcacg attgaattat
    40801 ttggtggctc gcctgacgac aacaacgcac taatcaatta caacggagtg atgtctgttt
    40861 tacaaccata tatggacaac ggtcagttgg tcgtgccatc tggacagacg agtttcagtc
    40921 aaatcgctac gcttcgctgg gatggttcta cggcgcaagc aaggatggat aatctgttaa
    40981 gcgcaaatta tactgaccaa acattggatg ctgttttgtc gccatatgat ccaataagtt
    41041 taggaatcat ttcgtcatta aaaggcgtgg ggtatgggag tgaaagtaaa cctttacctg
    41101 tgattactgg acaagatgcg acagttgctg gcgttaaatc gatcattgcc ggggaacaaa
    41161 cacaaacgat ctttaaagac acacgtatct tagcaaaaaa tacgattgaa atgatcaaag
    41221 caatcagtga tggagaagag gttccggtca atgatactga aacttatgat aatggggtga
    41281 aaactgtccc tacgtattta gcaaatacag tatctgtcga taaagataat tatcaagcag
    41341 agctgatcga caccgattat tataaagaat ccgatctgaa aaattaagag gaaccaaaca
    41401 aggaactaaa gagatctaag tcagagagag gataagaatt atggcggatt gtattttaaa
    41461 aatggcagat atcaccaaaa aattttctgg aatccgagcg ttagattgcg tgaatctgat
    41521 gattgaacgt ggggaaatcc atgcattgtg cggagaaaac ggagcgggaa aatcaacatt
    41581 gatgaatgtc ttgagcggct tgtatccata tggctcctat gacggggaaa tcttttatga
    41641 tggaaagctg tgtcaattta aagatttgaa agatagtgaa gaaaaaggca tcgtcatcat
    41701 tcatcaagaa ttagcactaa gtccttatct ttcaataaaa gagaatattt ttctcggaaa
    41761 tgaacaagca gaaagaggcg tgattgattg ggaactgaca gaaaagaaaa catatgaact
    41821 gctgaataaa gtcggtttgt ctatcgaccc gaatcttcta gtatcccaga ttggcgtagg
    41881 gcaacagcaa ctagttgaaa tagctaaagc attatcaaaa tccgtccgtc tgttgatttt
    41941 ggatgagcct accgctgcat tgaatgaaga agaaagcgcg aatttgctga gattgatccg
    42001 agagttgaaa gagcaaggtg taacctccat cattatttca cataagctga atgaaatcgt
    42061 ggatatcgca gatcgaatca ccattttacg ggatggacag acgattgaga cactagaaaa
    42121 tgaaatgatc agcgaagagc atattattcg cggaatggtg ggcagagatt tagttgatcg
    42181 ttatcctgaa agaaaaccgg atattggaga agtttatttt aaagtagaag actggacggt
    42241 ctatcaccct cttgatcacg agcgaatcat aaacgaccac atcaacttgc atttgaaaaa
    42301 aggagagatt gtaggaatag ctggactgat gggagcgggc agaactgaat tcgctatgag
    42361 tctatttgga cattcttatg gaagcaagat atccggacgt atattaaagg aaggggcaga
    42421 gatatcagtt aagaccgttc cttcagccat tgcaaacgga ctcgcttatg tctcggagga
    42481 ccgaaaatct ttaggactga atctgctgat ggatattcgg gaaaacgtga cgctgagcag
    42541 tttggataaa ataagtcaaa aaggagtatt agataaagaa aaagaagtaa ctgaggcaga
    42601 aaatttccgg aaaaagatgc gtataaaaac aaactccatc catcaaattg tcagtagtct
    42661 tagtggtggg aatcaacaaa aagtcgtttt atccaagtgg ctgatgacac aacccgatat
    42721 tctttttttg gatgagccaa cccgtgggat agatgttggg gcaaaatatg agatctacac
    42781 gattatcgaa gaaatggcag caaatggcaa agctgtctgt cttatctctt ctgaacttcc
    42841 tgaaatatta gggatgtgtg atcgaatcta tacgatgaac gaaggacgta ttacaggaga
    42901 agtctcgcga gaagatgcag atcaggaagt cttgatgaaa ttaatgacga aagaagaggt
    42961 gggttaagtt ggaacaggca aaaaatctta cggataaaaa agagaaaaaa ctaaatttga
    43021 aaagtagagc agctgatctt tttggtcgct acagcatggt gatcatttta gcgggactac
    43081 ttattgcgtt tcaattgatg acggatggta ttttctggcg tccattgaat ataactaacc
    43141 ttgttctgca aaatagccat atattagtac tagctgcagg gatgttatta gttgtgctct
    43201 taggtcatgt ggatttgtcg gtagggtcag tgatggcgtt tgttggtgca attgcgggca
    43261 tgatgatggt caatcgccaa atgaacccgt ggatgacagt tatcgcatgt cttgcagtag
    43321 gcgggctgat cggcgcatgg caaggttttt gggtagctta tgcagggata ccggcgttta
    43381 tcgtgacttt agcaggattg ctgatgtttc gtggactgac acaagttgtt ctaggaggcc
    43441 aatctctagc accttttcca gctgttttcc aaaaaatgtc tacgggttat ttaccagact
    43501 taagcgaagg aagcagcctt cacttcttga cattgatttt aggaatgatc atcacgatcg
    43561 tgttagttgt tggtcaatgg cgaacaagaa atcgtcggaa aaatcattta tttgaagtgg
    43621 aatctccaac agctttcttg gtaaaggcgg tatttacagc agtcgttgta ctaggaataa
    43681 cttatatctt tgcctcttat caagggtatc cgattatttt gatcattctt ggtttgatcg
    43741 ttgcagcata tgggtttttg acaaataaaa cagtagcagg tcgacagatt tatgcgacgg
    43801 gcggaaatcg aaaagcggct gaactatcag ggatcaaaac aaagcgaatc acgttctggg
    43861 tattcgtcaa catgggagtc atggcagctt tagctggatt agttttagct gctcgattga
    43921 atgcggcaac acctcaagca ggtacatcga tggaactgga tgcaatggcg gcagtatatt
    43981 ttggtggtgc ttcgacttcc ggcggcattg gaacaatcat gggtgcgatt gtcggtggct
    44041 tggtcatggg tgtattgaac aatggcatgt cgattttagg cgtcggggta gactggcagc
    44101 aggcaatcaa aggattgatc ttgcttttag ccgttgtgct agacttgtat aataagaaaa
    44161 aacgaacaac gtaggagaac gccggttatt cagaaaaaag actgtgacaa gacatttgtc
    44221 acagtctttt tttcgctaaa agcgaacatt cattgtttcg tttgtataga ctaaaaataa
    44281 tatatgtttt tttaccattc gtataaattc tctttttgct cttgattttt ttgcttaatt
    44341 gagttaaatt acatagggcg ctaaaaaaag ccttgattaa attaataatg ttcgtgtttt
    44401 gctggatgtg aacatcagga ggataatgta atgaaagtat ttgattacga agatattcaa
    44461 ttaattccta ataaatgtat cgtaaatagc cgttctgaat gtgatacaac ggtcacatta
    44521 ggtaaacata cattcaaaat gccagtagtg cctgccaaca tgcagacgat tattgatgaa
    44581 acaatcgcag aattcttagc ggaaaatggt tatttctata tcatgcatcg gtttgatgaa
    44641 gcagctcgaa ttccgtttat caaaaaaatg aaaaagcgtg gattgattac ctcgatcagt
    44701 gttggcgtca agaaagagga atattccttt atagagaagt tggcagaaga atcgctaaat
    44761 cctgattata tcactatcga catcgcgcat ggacatgcta actcagttat tgatatgatt
    44821 cagcatatta aaaaatattt gcctgaaact tttgtgattg ccggtaatgt tggtacaccg
    44881 gaagccgtcc gtgaattgga aaatgcgggc gcagatgcaa caaaagtcgg gattggtcca
    44941 ggaaaagtat gtattacaaa aatcaagaca ggctttggga ctggaggctg gcaactggca
    45001 gctcttagat ggtgtgcgaa agcagctcgc aagccgatca tcgctgacgg tgggatcaga
    45061 acacatggcg atattgcaaa atctgtccgt tttggtgcga caatggtcat gattggttca
    45121 ttgtttgccg gtcacgagga atctcctggc gaaacaaaag tcgaaaatgg aatcgtgtat
    45181 aaagaatact ttggttctgc ttcagaattc caaaaaggcg aaaaacgaaa tgttgaagga
    45241 aagaaaatct ggatccaaca caaaggatct ttgaaagata cactagtgga aatgcaacaa
    45301 gaccttcaat catctatttc ttatgctgga ggaagagatc tggaagccat tcgaaaagtt
    45361 gactatgtca tcgtgaaaaa ttcgattttt aatggagaca caatctaaaa aataaataaa
    45421 atattaggat gttgtgaaaa agttgtcctg cattaagtaa taagaacagc caaacaaaaa
    45481 tagttcttta tatgttttgt ttggctggaa ttattatcgc agatacaagc ttttgaacat
    45541 cattattcag aataagggac tgtgataaga tttttgtcac agtcccttat gttttgcaaa
    45601 aaaagttttt cttttttctc gtaaattcgg taaaatcaaa agaaaaaata gacaatagaa
    45661 aagagaagct tatgtgggaa aaagtagaga aaaaacaagg accgatttat cgtcaaatta
    45721 tggaacagat tatgagagaa atcgaaaacg gaaggatcaa tcctggaagt caacttgaat
    45781 cagaacgaaa actagggcaa ctttttggtg tgaatcgttc caccgttgtc catgcattgg
    45841 aagagcttag ggagcttggg gtactaacga gcaaacgtgg cagcggatgg tttgttaatc
    45901 agactgaatg ggggaaattc gctgttccaa gaatcgattg gcggcaaatg atctctcctc
    45961 gttatgagca gacggactgg tatgagcaaa aaataagaga agcaaagcag atccaaaaaa
    46021 catcgtttct tgatttatac gctagcgaga tgccagatga gcttttgccg aattttgagt
    46081 ttccttctta ttctcttgaa gaaatcttag cggaagaaaa agaaatggat cttttaggct
    46141 atactccgtt acgtaacaaa atcaaacggt atttggaaag taaatttgaa ttggcatttt
    46201 cccccaacca gcttcttgtg actggtggcg gtcagcaagc aatctttttg attttacaaa
    46261 cgattctttc agctggagag gggatagctg tagagtcacc ttcttttttt taccgattac
    46321 ctcttttcaa agcttcagga acgcgtttat ttgggatacc gatggatgaa gaagggatcg
    46381 acttagaaaa actgaaagaa tcgatccata aaaataaatt gaaagcagtg cttatcaacc
    46441 cgaattttca aaaccctaca ggaaaagtga tgagtcaaaa acgacgagaa aagctagtag
    46501 aattgtgtcg acagtatcgg cttccaatta ttgaagacga tgtatttacg gatctttcat
    46561 ttctaaacca agaagaagtc cttcctatac gaacgattga tccggataat gtgttatacg
    46621 tcggttcgtt atctagggtt ttaggaaaaa caacgaaaat cggttgggtg ataggacctg
    46681 agacttttat ctcgcaacta gctcaagcgc aagaaatgat ggagttttcg atgaatatcc
    46741 ttacacaaat cacagtggct aatgtattta atgaagcaat tgatttgaaa atgcaagatg
    46801 taagaaaaaa gttgaaagaa aaaagccgac tgataagcgc ttggggagat tcacaatcgt
    46861 ttttcaagct tcattcaatt ttaggtggtt actatgcctg gattacttgg gatgggaaaa
    46921 aactagaccc cgaactagca gaaaaagtag tagatatggg tcttggaatt gcaccaagtc
    46981 tactttttgg gcaagatata aatggaatca gaatcaatta cagtaggctg gatgaaaacc
    47041 aaataccgtt gttttattca aagatgaaaa ttctagaaaa gtggttaaca gaataatttc
    47101 acaaagtaaa tagattaaag aatataacag cttggattta aatttcaagc tgtttctttt
    47161 ttttcggaaa aagaatacga tataaagaaa ctaagaaaaa accattattt gtacgtccgt
    47221 tcacgatgtg taaataaaat aaatgtttgc aacaaaactg tataacacca acgtttttaa
    47281 atagaaacag atggttgtaa gtttgattag aaaatagaaa aaatgcagat gaaatataaa
    47341 acgctttcct tattgtgatt ttattcacta atgctgttaa tatgcggatt ggcataattt
    47401 cctttcatcg tgaaaatttg tgcttttagc ttgtatttct cataaatcca tgataattta
    47461 ttaatgaaga cggttaaata gtgatacagt tttattcact gtttcaatcg cagaatgaag
    47521 agattttctt atagatgaga gaggaatgtg tgacaaatgg caaacaaaaa agcaccgatc
    47581 gacttccaag cactgctaga tgaagtcaat gcagatttcc cagtatatca agcacttgat
    47641 caagatggaa acgtagttaa caaagattta gtacctgatt tatccgatga tgaactcgtt
    47701 gaattaatga ctcatatggt atggtctcgt gtattagacc aacgttcaac agcgctgaac
    47761 cgccaaggac gcctaggctt ttttgcacca actgctggac aagaggcaag tcagctggct
    47821 agtgcttacg catttgataa agaagatgtt cttcttccag gttatcggga tgtacctcaa
    47881 ctagtaaaac atggtttacc tttatctcaa gcttttttat ggtctcgagg acatgctgca
    47941 ggtaattctt atccggaaga attgaaagct ctaccaccac aaattatcat cggtgcacaa
    48001 tatgtacaag cagccggtgt tgcattaggt ttgaagaaac gaaacaagaa aaatgtcgtc
    48061 ttcacttata ctggtgatgg cggttcatca caaggtgatt tttacgaagc aatcaatttc
    48121 gctggcgctt accatgcaaa tgccgtattt tatatccaaa acaacgggta tgcgatctct
    48181 acacctcgtg aaaaacaaac tgcagcaaaa acacttgcac aaaaagctgt cgcagctggg
    48241 attcctggta ttcaagtcga tggaatggat ccgcttgcag tatatactgt atctaaaatg
    48301 gcacgggaat gggcgatcag tggaaatgga ccagtcctaa tcgaaacact gacttatcgt
    48361 tatggaccac atacactatc tggtgacgat ccaacccgct accgtacaaa agacacagat
    48421 gacgattggc agaaaaaaga tccattgatc cgcttccgta aatatttgac ggaaaaagga
    48481 ctttggtctg aagaaaaaga agaacaagtc atcgaagcaa ctaaagaaga aatcaaagca
    48541 gctattgctg aagccgacaa agtaccaaaa caaaaggttt cagatttctt gaaaaacatg
    48601 ttcgaagtat ctccacaatc aatcaaagaa caaattgcaa tttatgaagc gaaggagtcg
    48661 aaataatcat ggcacaaaaa acaatgatcc aagcaatcac agatgcctta gcacttgaac
    48721 tagaaaatga cgagaatgtc gttgtttttg gtgaagatgt tgggaaaaac ggaggagttt
    48781 tccgggcaac tgaaggattg caggaaaagt tcggagaaga ccgagtattc gatactcctt
    48841 tagctgaatc tggaatcgca ggattgagtt tcggtcttgc gttagaagga tttcgtccag
    48901 ttcctgaaat ccaattcttt ggttttattt tcgaagcaat ggacgaagta gtagctcaaa
    48961 tggctcgtac aagatatcga atgagcggca ctagaaatct acccatcaca attcgttcgc
    49021 catttggtgg cggtgttcat acaccagaat tgcattcgga taatttagaa ggtttgatcg
    49081 ctcagtctcc tggtattcga gtagtgattc cttccaaccc ttatgatgca aaaggactat
    49141 tgatttcttc tattagaagt aacgatccgg ttgttttcct agaacacatg aaactatatc
    49201 gctcattccg agaagaagtg ccggatgaag cttacgaagt tcctttggat aaagcagcag
    49261 ttactcgtga gggaacagat gtatctatta tcacatacgg agcaatggtg cgtgaagcaa
    49321 tcaaagcagc agacaatctt gcaaaagaaa atatatctgt tgaaatcatt gatcttcgta
    49381 cagttgcgcc attagatgta gaaacgatca ttcaatccgt ggaaaaaact ggtcgcgtag
    49441 ttgttgtcca agaagcacaa cgacaagcgg gcgttgccgc gcaagtagtt tctgagatct
    49501 cagaacgcgc tatcctttca ttagaagccc caatcggacg agtttctgca cctgatacag
    49561 tcttcccatt tggacaagca gaaaatgtct ggttgccaaa tgcaaaagat atcgaagaca
    49621 aagtaaaaga aatcgcggaa ttttaagaaa agaagggacg aaacaaagtc atggcttatc
    49681 aatttaaatt gccggatatc ggtgaaggaa tcgcagaagg tgaaatcgtc aaatggttcg
    49741 tcaaaccagg agatacgatc aatgaagatg atacattact agaagttcaa aatgacaaat
    49801 cagtagaaga aatcccgtca cctgttacag gaacggttaa aaatgtgatt gttccagaag
    49861 gtaccgtagc aaatgttggg gatgtattag tagaaatcga tgcaccagga cacgaagaca
    49921 atgaagggga cagtggtgta gccgcagaat cccaaactcc agctaaaccg gctgctgaac
    49981 ccactgttga tacagaatca gctggatcgt caagcgaagg agtcttccaa tttaagttac
    50041 cggatatcgg tgaaggaatc gcagaaggtg aaatcgtcaa atggttcgtc aaaccaggag
    50101 atacgatcaa tgaagatgat acattactag aagttcaaaa tgacaaatca gtagaagaaa
    50161 ttccgtcacc tgtcacaggg acagttaaaa acgtgattgt tccagaaggc actgtagcaa
    50221 atgttgggga tgtattagta gaaatcgatg ctcctggaca caatagtgca ccgtcaacta
    50281 gtgcgccatc agctgaagca ccaaaagaaa aagtggaaac atcaggttca gcaagtgtcg
    50341 ttgaagctgc cgatccaaat aaacgtgtat tggctatgcc atctgttcgt caatttgccc
    50401 gtgaaaaaga tgtagatatc tcacaagtaa ctgcaactgg aaaaggtggc agagtaacaa
    50461 aagaggacat cgaaaacttc ttggcaggtg gtccaagcag tgcaccagcg aaatcagaag
    50521 cgccagaagc ggcagcaccg aaagaagcag ctcctgcagc agaaagcaaa ccagctgcac
    50581 cagcaaaacc attcaagtcc aacttaggag acttggaaga acgtgtagca atgacgccaa
    50641 cacgtaaagc tatcgctaaa gcaatggtca acagtaagca tacagctcca cacgtgacat
    50701 tgcatgatga agtagaagtg tctaaactat gggataatcg gaaacgattt aaagaagttg
    50761 ctgctgcaaa tggtacgaaa cttactttct tgccatatgt cgtgaaagct ttaacagcga
    50821 ctgttaagaa atacccagta ttgaatgcat ctatcgacga tgcaaaccaa gaaatcgttt
    50881 ataaacatta ctacaatatc ggtattgcaa ctgatacgga tcacggacta tatgtaccaa
    50941 atgtgaaaga tgcagaccgc aaaggaatgt ttgctattgc agacgaaatc aatgagaaag
    51001 caaaattagc tcatgacggc aaactatctg cagaagatat gcgcaatgga acaattacga
    51061 tcagcaatat cggatctgta ggtggcggtt ggtttacacc agtcatcaac tatccagaag
    51121 tagctatttt aggtgtagga acgattgcac aacaaccaat cgtaaatgct gaaggcgaaa
    51181 tcgttgtcgg tcgtgtgatg aaactgtcat taagtttcga tcaccgtatc gtagatggag
    51241 caactgcgca acaagcaatg aataatatca aacgtctttt agctgatcca gagctattaa
    51301 tgatggaagg atgataaaca aatggtagtt ggagattttg ctgtagaatt agatacagtt
    51361 gtaattggtg cgggacctgg tggctatgta gctgccatcc gcgctgctga aatgggacaa
    51421 aaagtagcaa tcattgaaag agagtatatt ggcggtgttt gtttgaatgt cggctgtatt
    51481 ccttcaaaag cactgatagc tgcaggacac cattatcaag agtcactaga ttctgaaatg
    51541 tttggagtaa ctagtgaaaa cgtcaaacta gattttgcaa aaacacaaga atggaaagaa
    51601 aacaaagttg tccatacgtt gacttctggt gttggtttcc tattaaaaaa acataaggtt
    51661 gaaacaatcg aaggagaagc gttcttcgta gatgatcaca cactacgcgt cattcatcca
    51721 gattcagctc aaacttattc gttcaataac gcaatcatcg caacaggttc ccgtccaatc
    51781 gagattccag gatttaaatt cggaggacgt gtgttagatt ctactggcgg attagcattg
    51841 aaagaagtac ctaagaaatt tgtgatcatc ggtggcggtg tgattggtgc cgaattgggc
    51901 ggagcgtacg caaacttagg agcagaagta acgattcttg aaggctcacc acaaatttta
    51961 ccaacttacg aaaaagatct agtaaaatta gtagaagatg atttcaagaa aaaaggcgta
    52021 acagtcgtaa cgaatgcaat ggcgaaagaa gcagtcgata acggtgacag cgtgacagtg
    52081 aaatatgcag tggacgggaa agaagaatcc gttactgctg attatgtgat ggtcactgta
    52141 ggtcgtcgtc cgaatacaga tgatatgggc ttagaacaag cgggtgtcga agtaggagaa
    52201 cgaggattga tcacggtgga taaacaagga cgtacgaacg tacctaacat ctatgccatc
    52261 ggtgatatcg ttccaggggc ggcattagca cacaaagcca gttatgaagc aaaaatcgct
    52321 gctgaagcaa tctctggcaa aaaagtagct gtagattata aagcaatgcc ggcagtagcc
    52381 ttcactgatc ctgaattggc ttctgtaggt atgacgatca aagaagcaaa agatgctggt
    52441 atcgaagcaa aagcatataa attcccattt tcagggaacg gtcgggcatt atcgcttggt
    52501 aaaacagaag gattcatccg tctagttacg acgatcgaag ataacgtgct tattggcgcg
    52561 caaatcggtg gagtcggcgc aagtgatatg gtctctgaat tagctttagc aatcgaatca
    52621 ggaatgaatg ctgaagatat cgccttgacg attcatcctc atccatctct tggcgaaatc
    52681 gtcatggatg cttcggaatt agcattaggt ttaccaatcc atatttgatt tgaataatac
    52741 aggcgaaacg caactgaaaa atcagttgcg ttttgttttt tagaattatc aataatatta
    52801 ttatgtaaac ttaaaaatat gacaacttct tggtttatta ccacttccta tgctacactg
    52861 aagaggaata tgaaatagga gagttgaaga tgcaagaata tcagtatcca cttgatttag
    52921 attggacaac agacgaaatg gtcattgtaa tgaagatgtg ggaagatctg gaacgtgcga
    52981 atgaaaaagg gataaacaat gaagcttttt tgaagactta tcagcagttt aaaactgttg
    53041 tcaaatccat tggtgaggaa aaacgattgg gacgggaatt tgaaaaagct tccggttatt
    53101 ctttatatcg tacagtgcag caagcaaaaa aaaatccaaa caaaactttg agaatgaacg
    53161 ggtgagataa atggaacaga tgattgatca tatcaagtcc tggcttgaag aagctggtga
    53221 gaaaatcaaa tcttctcaac aaacattaac aatctcgcaa aaatcaaatc gaacggatct
    53281 agtaacaaat gtcgatcgaa acatccagaa ttttctaatc gaaaaaatcc attcctttga
    53341 tccagaggcg aaaatattgg cagaagaaga agggtgtaat caattatcgg atctcgatgg
    53401 aagagtcttt atcatcgatc ctattgatgg caccttgaat tttgtgattg aaggggaaaa
    53461 tttttgtatt atgctcgctg tttatgaatc cggcgttgga aagcttggtt tcatttatga
    53521 cgtgatgaga aatgaacttt tttggggtgg aaaaggaata ggcgtgtata aaaatgatga
    53581 gccattgcct agaccagcaa ataaatcctt atcggaaggc ttacttggtg tgaatagtta
    53641 tcttttcggt cataataaat atggaatccg agaaattgcg gaaagcagca tggggacacg
    53701 tatgtacgga tgcgctggtc ttgaactagt ggcaatcttg aaaggaaacc acattgctta
    53761 tatttcaaac cttagccctt gggattatgc agcgggaaat gtcttattgg aagagtttgg
    53821 tatggtaaca agcggtcttt ttggtactcc tttgacattt gaaaaaaggg aatactattt
    53881 agcagggact tcttgtgcat atgcagaaat cgcagacctt ttgaaaaaag aaggctgaaa
    53941 aaaaggtaga aatcattcac aaaaatgata aaaacgagca aaagattaat tttctcgaaa
    54001 aaatgaaaac attttactat atttcatgaa aaaagtctgc tataattagc agtcgagtaa
    54061 aatttgccct gtcataaaga accaataaaa aaggagttag ttacattgaa ttatagaaac
    54121 gatatccgta acgtcgcaat tattgcccac gttgaccacg gaaaaacaac attagttgat
    54181 gaactattaa aacaatcaga tacattagac gcacatacgc aattgcaaga acgtgcgatg
    54241 gactcaaatg cgctagaaaa agaacgtggt atcacgattt tagccaaaaa cacagctgta
    54301 gactataaag gtattcgcgt aaacatcatg gatactccag gacacgcgga cttcggtggc
    54361 gaagtagaac ggatcatgaa aatggttgac ggcgttgtgt tggtcgtaga tgcgtatgaa
    54421 ggaacaatgc ctcaaacacg ttttgtattg aaaaaagcac tggaacaaca tatcacacca
    54481 atcgttgtcg taaacaagat tgacaaacct tctgctcgtc ctgagcatgt cgtagatgaa
    54541 gttcttgaac tattcatcga attaggagca gatgatgatc agttagactt tcctgtgatt
    54601 tatgcatctg cactaaatgg tacgtcaagc ttgtcagatg atccagcaga tcaagaacca
    54661 accatggcac ctatttttga tacaattatt gaaaaaatcc ctgctcctgt cgataacagc
    54721 gacgaaccat tacaattcca agtttcatta cttgactaca acgattatgt aggtcgtatc
    54781 ggaatcggac gtgtatttag aggaacaatc aaagtaggag accaagtagc attaattaaa
    54841 ttagacggaa cagttaagaa attccgtgta acgaaattat ttggtttctt tggactaaaa
    54901 cgtctagaga ttcaagaagc aaaagctgga gacttgattg ctgtctcagg tatggaagat
    54961 atctttgtcg gtgaaacagt tactcctgtg gatcatcaag atgcgttacc tatccttcac
    55021 attgacgaac caacattgca aatgactttc ttagttaata attcaccatt tgccggtcga
    55081 gaaggtaaat tcgtaaccgc tcgtaagatt gaagaacgtt tgatggcaga acttcaaaca
    55141 gatgtatcct tacgagttga accaacaaac tctccagatg catggacagt ttctggtcgt
    55201 ggagaattgc atttgtctat cttgattgaa aacatgcgcc gtgagggata cgaattgcaa
    55261 gtatctcgtc cagaagttat tgaaaaagaa atcgacggtg taaaatgcga accgtttgaa
    55321 cgcgtgcaaa tcgatacacc agaagaatat atgggtagtg ttatcgagtc cttgagctta
    55381 cgtaaaggtg aaatgcaaga tatggtccat acaggaaacg gacaaatccg tttgacattc
    55441 ttaacacctg cccgcggttt gattggttat tcaactgaat tcctttcaat gacacgtggt
    55501 tacggaatca tgaaccatac ttttgaccaa tatctgccaa tgcttcctgg tcaaattggc
    55561 ggacgtcacc aaggggcgct tgtttcgatc gatacaggaa aagcaacgac ttattctatc
    55621 atgagtatcg aagaacgcgg tacagtcttc gtagaaccag gtacagaagt atatgaagga
    55681 atgattatcg gggaaaacag ccgtgataat gatttgactg tcaacatcac gaaagcaaaa
    55741 caaatgacaa acgtacggtc tgctactaaa gaccaaacat ctgtcatcaa aaaaccaaaa
    55801 caattgacgt tggaagaatc tttggaattc ttgaatgatg atgaatattg cgaagtaaca
    55861 ccagaaagca ttcgcttgag aaaacaaatt ttagagaaaa atgctcgtga aaaagcatct
    55921 aaaaagaaaa aataatctgt aaaaggatga agagagaaac cagcttgtta taaaaaatag
    55981 ctggtttctt tttttgtcca actcttttct gtggagaagt catctttgtc aatggacata
    56041 aattcagaaa atacgccgaa agacgtttaa aagactttta aaaaacttat ttctagagag
    56101 tttttgtttc ataataagat aatgtttcac gaaaggagat caacttgtcc ttcgaagaaa
    56161 atcgaagtaa aatggcaaga gaaaggagcg ggaagatgaa cgacttatta aaacaatact
    56221 ttggctatga tgagtttaga cctggtcaaa aagaaattat ccagaaagtc attgatcagg
    56281 aaaatgtatt aggaatcatg cctaccggaa gtgggaaatc aatctgttac cagcttccag
    56341 ctttactatt agatgggctt actgtggttg tgtccccttt aatctctttg atgaaggatc
    56401 aggtggacgc ggcgaatcaa ttaggtatac ccgccacttt tatcaatagc tcgttagatg
    56461 gttacgaaac agctagacgc ttccaagaaa tcgatagaca gcagtaccgt ttactttata
    56521 tcgctcctga acgttttatc atgccggatt ttatccaagc aatgaagcga tggaacgtcc
    56581 gtatgatcgc tattgacgag gcacattgta tctctcagtg ggggcatgat ttccgcccaa
    56641 gttatttaca gatggcgaac cagctagatc aactgccaaa tcgtcctgta attgttgctt
    56701 tgacagctac agcgactgtg caagtagctg ctgacataaa aagactttta aaaattccag
    56761 aaaacaacca tattcagact ggttttgaac gagaaaatct acgatttcaa gtaattaaag
    56821 atcaaaaaaa agaacaatat ctaatcgaat atttaaagat caacaaaaat caatctggta
    56881 tcatttatgc agcaacgaga aaagaagtag accgtctcta tcatttgctt aaaaaattcg
    56941 atttttccgt gggtagatat catggtggtc taaatgagaa tgagcgaaca gaaatgcaag
    57001 aagccttttt atacgatcgc ttgcagctga ttgtagcgac aaatgcattt ggtatgggta
    57061 taaataaaag caatgtccgt tttgttatcc attatcaaat tcctggctct ctagaagcat
    57121 actatcagga agctggtcgg gcgggaagag atggtctttc cagtgaagcc atcctgcttt
    57181 tctctcctca agatatccaa gtccaaaagt tttttatcca gcagtcccaa agagaagaag
    57241 ggcaaaagca aaaagaatat gaaaaattaa aagcgatgac agaatacgtg tatattgagt
    57301 cctgtcttca gcaatacatc ctaaactatt ttggcgagac aagcagtccg tgcaaccgtt
    57361 gtggtaactg tttagatgac agagaaatag tagaagtaac gacagaagca cagatggttc
    57421 tttcttgctt aaaacgtatg ggtgagaact atggtaaaca aatgctgatg aaagtcttag
    57481 caggatcgaa agaacaaaag ctgcaagctt taggttttgg acatttatct acctatggac
    57541 tgatgaaaaa ccaatcgcaa aaagaaacga tgcagttaat tgaatatttg atatcgaatg
    57601 gctatcttct gaccatcaat ggtgagtatc ctgttttgaa agtaacagaa agagggatac
    57661 aagtattgaa aggacaagaa tctgtttatc gaaaggaacc caagaaagtc cagcagctat
    57721 cggatgaaga aaccgataca ctatttgaag tgctgcggga actgcgaacg gatctagcat
    57781 cagaagcagg cgttcccccg tatgtcgtat tttcagattc cacattgaaa gaaatgagcc
    57841 gaatacgtcc atcaagcaga ttggagatgc ttcagataaa aggagttggc caaagcaagc
    57901 ttgataaata tggcgaagcc tttttatctc ggataaaaaa tgcggactct aacgttctgg
    57961 ataagtagaa agaacgaata cgtaaaaatg aataaaaaca actggttaaa tctgtttttt
    58021 ttgctcctta tgaaaatcaa atatgttata attaaggaat tagaatggga ggtaagcaca
    58081 gatggattct ttgtcgaaaa aacttgcgat ccaagtatta aatgatgaag cagaacggat
    58141 caaacgatta atccgaaatc aaaacaacag tctctgtatc tcacaatgca aagccttcga
    58201 agaagtggta gatacacaga tgtacggctt ttcccggcaa gtcggttttg ctgtccgtat
    58261 aggagtaatc ggaaagaacg agggccagct gatgttaagt gagctagaac gagaattgaa
    58321 tcagttatat agtgaggttt accaagaaat ttatgataaa aaagaagttg gcaaggagga
    58381 atagacttgc ctaagaaagt gaaaaaaagg catctattag actatagcat cttgattccc
    58441 tatttaattt tatgtgtatt gggattgatc atggtatata gttctacgtc gtatctatta
    58501 ttagaaaacg gacaaaatcc gtccgcatca gtcattaacc agagtatttt ttgggtgctt
    58561 agcttgattg ctatcgcact actttataaa atgaaaacag atgttttgaa aaaccagcgt
    58621 ttgatcatgg cagccatcgc agttttgacg attttgctgc tgattgttgt gttttttggt
    58681 aaggagatca atggggcgaa aggttggctg caaattgcag gattctcgat ccaacctgcc
    58741 gaatacctaa aaatcatttc tatctggtac ctgtctctga ctttatctaa aagacaaaac
    58801 agtgtacaaa aaaattttct tgggactgtg aaacgtccac ttgcaatggt tatcggactt
    58861 actgcattag tcgctattct tcccgatttt ggtaatgcgg cagttatctt tttgattatt
    58921 ttggttctgc ttttagccag cggagtcaat tatgtgtata ctttgattgt aggagtagga
    58981 ggcttttgtc taagtacttt tacgatctgg ctgatcaata tcacaaacgg aaagatctta
    59041 cccggacgtt tacagtatat ctataatcga tttgctattt accaaaatcc tttctcagac
    59101 gaattaaata aagggcatca actagtcaac ggctactatg ccatgttcaa cggaggacta
    59161 tttggcaggg gattaggtaa cagtatccag aaaaaaggat ttttacaaga agcacaaacc
    59221 gattttattt atgcaatcgt agtggaagaa ctgggagtga ttatggggat tttgatatta
    59281 gcgttgctat tctttatgat tgtgcgcatt gtccttgtag gtatccgttc aaaagatccg
    59341 ttcaattcgc ttttgtgcat tgggatcggc gcaatgtttt tgatccaagt atttgtcaat
    59401 cttggaggaa ttactggcgt tattcctttg acagggatca cgttcccatt tttaagtcaa
    59461 ggaggctcca gtttgctgat gctttcgatt tgtgtcggct ttgtcctcaa catcagtgcg
    59521 gatgaaaaac gcaagagctt aggtttataa taaaaaaaga tgtaggagtg gttcgatgaa
    59581 aaaagtttta gttgctaaca ggggtgaaat cgctgtacgt gtatttcgtg cttgtacaga
    59641 attaggaatt aaaactgttg gaatctatgc agaagaagat gaatattccg tacaccgttt
    59701 caaagcggat gaagcatatt tagtaggaca aggaaaaaaa ccgattgatg cgtatctaga
    59761 tattgaaggg atcatttcta tcgcgaaaga atgcggagct gacgctattc atccgggtta
    59821 cggtcttttg tcggaaaact tgaattttgc gcaacggtgc gaagaagaag gcatcatttt
    59881 tgttggaccc aaactgcatc atttagatat ttttggagat aaaatcaaag caaaagctgc
    59941 agctatcgaa gcggggattg cttcgattcc aggcacagat ggaccaatcg cttctataga
    60001 cgatgccttg gagtttgcga aacaatacgg ttatccgatt atgatcaagg cagctctagg
    60061 cggcggcgga cgcggcatgc gtgtagctca cgatgaaaag agtgcaagag agggctacga
    60121 acgtgcgaaa agcgaagcaa aagcagcctt tggtagtgat gaagtgtatg ttgaaaaata
    60181 catcgctaat cctaagcata tcgaagtaca gattctcggg gatacgcatg gaaacgtcat
    60241 ccatcttttt gaaagagatt gttctgttca gcgccgtcac caaaaagtag tagaagtagc
    60301 gccttgtgtc tctatgaatg aacagcaacg tcaaaaaatc tgccaggcag ctgtccaatt
    60361 gatgaaatat gtcgggtatg tcaacgcagg tacagtagaa tttcttgttg aaggagatga
    60421 tttttacttt atcgaagtca accctcgcgt ccaagtggaa catacgatca cagaaatgat
    60481 tacagatatt gatatcgtaa caacgcaact gttgattgct caaggtttgg atctgcataa
    60541 agaaatcgga ttgcctcagc aagaaggaat taaattaaat ggttcagcca ttcaatgccg
    60601 aatcactaca gaagacccgt tgaataactt tttaccagac acagggaaaa tcgatacgta
    60661 tcgttcacct ggtggttttg gcgtacgtct ggatgtcgga aatgcttacg cgggctatgt
    60721 agtgacaccg tattttgatt cattgctagt aaaagtatgt acgcatggtg ctacctttga
    60781 aacagccatt cagaaaatgg aacgttgctt gaaagaattt agaatccgtg gagtgaaaac
    60841 aaacattcca tttatgctca atgtcatcac acatcctgaa ttccaatcag gaaatgcaaa
    60901 aacaaccttc attgatagta cagcaacatt atttgaattt cctcgactac gagaccgcgg
    60961 aaacaaaacg atgaaatata tcggtgaaat tactgtgaat ggttttccag gtatcgaaag
    61021 tggcgaaaaa ccattttatg aagaaccacg tatgcctaaa gatctaatca caagaactga
    61081 ttacgtaacg gctaagaatg tattagatgc gaagggtgcc gatgctttgg tcgaatggat
    61141 caaaggacag gaaaatttgt tgttgacgga tacgacattt agagacgccc atcaaagtct
    61201 gctagcaact cgtgttcgga caaaggattt caagcagatt gcacgtttga ctggagaagg
    61261 tcttcctgaa ctcttttcaa gtgagatgtg ggggggagca acatttgatg tggcttaccg
    61321 ctttttgaat gaagatcctt ggcaacggtt gagaaaaatt cgttctttaa tgcctaatac
    61381 gttgctgcaa atgcttttca gaggttcaaa tgccgttggg tattctaatt atcctgacaa
    61441 tgtattggtg gaatttgtca aagaagcagc agcgcaagga atcgatgtat ttcgaatctt
    61501 tgatagtttg aactggactc cacaaatgga aaaaagtatc caagctgtac gggatactgg
    61561 taaaatcgca gaggcagcta tttgctatac tggcgatatc aacgatccaa gtcgggcaaa
    61621 atacaatgtt cagtattata aagacatggc aaaggaacta gaacaactgg gtgcgcatat
    61681 cattgcaatc aaagatatgg ctgggctgct taaaccgcag gcagcttatc gtttgattag
    61741 tgaattgaaa gaaacgacag atctgccaat ccatctgcat actcatgata ccagcgggaa
    61801 tggaatcatc acttattctg ctgcttcaaa agcaggagta gacatcgttg acgtggcaat
    61861 gagtgcaatg agtgggaata ctagtcagcc tagcatgagc agcttgtatt atgcactggt
    61921 caatggtcca cggctgccag aaatcacgat tgaaaatgca cagaaattaa accattattg
    61981 ggaagatgtg cgcatgtatt acaaaccgtt tgaaaacggc ttgaatgctc ctgaaacaga
    62041 agtatatatg catgaaatgc caggaggaca gtattcgaat ctacagcaac aggcaaaagc
    62101 tgtcggatta ggtcatcgct gggatgaaat caaacaaatg tatcatactg tcaacttgat
    62161 gtttggcgat atcgttaaag taactccatc atctaaagta gttggagata tggcactatt
    62221 tatggtccaa aatgatctta cagaagaaga tatttatgaa aaaggcgaaa cactaagttt
    62281 ccctgaatct gttgtgactt tcttccaagg agaactaggg caacccgttg gcggatttcc
    62341 taaaaaattg caaaagatta ttcttaaagg cagacctgca ttgaatgaac gtccaggtct
    62401 tttggctgaa tcagtcgact tcaacgaagt aaaaaaagaa ttggcagaaa aaattggcta
    62461 tgaaccaaaa caagacgaag tattaagcta tttgatgtat ccgcaagtct ttttggacta
    62521 tcaaaaagca tataatcaat ttggcgatgt tacattactg gacacaccaa catttttcca
    62581 aggtatacgt ttgggtgaaa caatcaatgt acaaatcgaa cgcggaaaaa cgcttatcat
    62641 tcgtttagat gaaatcggag aacccgatat cgaagggaat cgcgtactgt tcttcaattt
    62701 gaatggacaa agacgtgaaa tcactatcaa agataattcg atcatcagta cggtccaaac
    62761 ccgattgaaa gctgaaccga caaaccgaga acaaattgga gcaacgatgt ctggttctgt
    62821 tttggatgta ttagtgaaaa aaggcgataa cgttaaaaaa ggtgatacgt tgatgattac
    62881 tgaagcgatg aaaatggaaa cggccatcga agcacgtttt gacggagaag tcgcacatgt
    62941 atatgtgtct tcaggagaca ctatttcgtc tggtgacctt ttgattgaag tgactgagaa
    63001 ataataagcg aaaggtgggg aaacatgaaa agactgggtt tgttttggct gattctgcta
    63061 ttagttattg tggcattcta catggaacca gtcttgtttc cgccaaaact tgaagtgaag
    63121 gaaaactctg atcaacaaat atcaaaccaa atgacaacgt ggaaatacca ggagcttaaa
    63181 gcaactggtt tttctactta tatcggaaaa ccgatcgatc agctggaaaa ggattttggc
    63241 caagcctatg atcgattaac tagcggattt ggttttgaaa caagatatta tgaaaataaa
    63301 gctagtcatc tcacatttga agcgaacatc caagacagca gagtcacaac tgttaaagta
    63361 ctgcaaacag ggcctgctga tatcgcgccg ttttatttag ggatgacgat gcaagatctt
    63421 acgaaaatca ctactatcta tactaatttc acttttgagt accatgatac agaagttgga
    63481 atcgaactaa tggaagagga tatgaattat cgtccgctaa ttgcttttga taacgacact
    63541 tttgctattt tattttttga tcaaacaaca aacggcctat tttcagttgt gtatttagat
    63601 aaagatagtc ttttgaaact attgccatat caagtgtttg gtgaaggcct tccacattat
    63661 caagcagata aatcggctga ttgggaatca atcaatcgcg ttaaagaacg aaaaagtacg
    63721 actttattaa atatgcttag aagagaagac gaacttccca tatacaatca aacacttgcc
    63781 tttcaaaacc acagtcagct gctactacat gattttttga caaggcctga ggaaatattg
    63841 tcagaggaac gtatggctga ttggcaaaaa tcgctaggca gtgctcaaac gacagtgaaa
    63901 ttctcactga cgaatgatga attggagaag ttaatcagta aacaaaaatt agaaaatact
    63961 agtgggctat ttattcatcc ggcgattgac gctacttttt cgtttttata ttggtacagc
    64021 gatccttaca accatgaccg tttcatggac ccgggaacgg attctgtagg cattgctttt
    64081 tctaaagaaa atatgttagt cttattgcaa gaagaaaacg gagaaagtag tgatagcagt
    64141 gatcgttaac gaagagctgt ttcaactgga ggatcaatgc ctccaagtcg ctgaaatgat
    64201 aaaaaagagt aaaacgatgg cttcttatct tgaacataaa cagtcaatgg aagaatctgc
    64261 aaaagtttgc cagttgaaag aagcgttctt gtctaagaaa gaagcatttg aaaatgtagc
    64321 ggcatatggt gagtatgcac ctgattatcg tgaaaaaaaa cgagttgttc gaaaagcaaa
    64381 aagacagctt gatatggatg agcatgttgc agctttccga tatagtgaaa cacagctgca
    64441 aagtctgttg gatcaaattg tccaagtact tgccgaagaa gtttctaatg aaatcaaagt
    64501 agatgcaggt agcccgtttt ttgaaacgaa aaaacacttt ggatgcggag gtaattgtca
    64561 tgcaattaga caatagtgaa tttgaaataa caaaacgacg cgggctgatc gtatgggtct
    64621 acagcttaaa acaattaaag aatctgaaaa agttcggctt gttgcattat gtctcaagaa
    64681 gaatgaaata tgtcgtgctt tacttaaatg aagagacatt ggaagaaaca gaagaacgaa
    64741 tccgtaaatt acattttgtt cgaaacgtag aacgttctta ccgaccggat atcgaaatga
    64801 attttgccga aaaaatagga aacaaaacag tattaaaaga cgaaggtttc gaaattgaag
    64861 agctaaatac agaaatccga ttagctgaac atctttaaaa atctcttatg agcagttttt
    64921 aaataaaaaa taacttggat aacgatcgat ttttgatcat tgtccaagta tttttttggt
    64981 atactagtac cagtaccatt tctaaggagt gagtagatgc ggataatatc aggaaattat
    65041 ggcgggcgcc gtttaaaaag tttagcaggg gcgaacacca gaccaactac agataaagta
    65101 aaagaatcca tattcaatat gattggacca tattttgatg gagagacagt attggatctg
    65161 tttgcaggaa gcggtggttt agctatcgaa gcagtatcta gaggctgcag tcatgcggta
    65221 tgcgtagaca aaaattacca agcgctaaaa atcatcaaag aaaacatcga aattacgaaa
    65281 gaaccagaga aatttaccac aataaaactt gatgcggaca aagcaatcga acggctagca
    65341 gcggagaaac aacaattcga ctacttgttt cttgatccgc catatgcaaa acaaaaaata
    65401 atcgatcaaa tccataaaat ggaagaactg ggactttttt ctaaaaccgc agttatcgta
    65461 tgcgaaacgg ataaaacagt cgaattgcca gaaactgtgg ctggattcca tcaaataaga
    65521 aaacagattt atggcataac ggccgtaact atctatagaa aagagggaaa tcaatgaaac
    65581 gtgcattatt cccaggaagt tttgatcctt ttacaaaagg tcacttagat acggtggaac
    65641 gtgcggctaa attattcgat gaggtagtaa ttggtgtttt tatcaatact tcaaagaaaa
    65701 gtttgtttcc cccagaagaa agaatgacat tgatcacaaa agctgtttct catcttccta
    65761 atgtaaaagt catgcatcaa gaaaatcaat tgacggtaga aacagcaaaa gagattggtg
    65821 cagatgcgtt gatcagaggc atacgaagta tcaaagactt tgaatatgaa cgagagattg
    65881 ctcagatgaa tcatcatcta tatgatgaat tggaaactgt cttcttatta gcaaaaccag
    65941 aatatagtca cgtgagttcc agtattttaa aagaagtact gcactttggc ggagatgtga
    66001 gcagctactt accgccagtg atcaacgaag ctttagctgg aaagcgtgaa tcaaatgaaa
    66061 gctaaacaat ggttgaaaac agtactgatt atcatatttg gaatgttgat cattggattt
    66121 gtagtagttc ccttgccgta ttatgtagaa tcaccgggag ccacgatcga tctgaaagaa
    66181 ctaattacgg tcaatgataa ggaagataaa ggttctgggt ctttctctct tacctctgtt
    66241 ggtatcaggc aagctacagg tttcttagct ttaaaagcta aaatgacccc ttttgaagaa
    66301 ttgatcagtg aagaagaatt gactggtggg gcgacaaatg aagaatataa tcaaatgcaa
    66361 cagtattata tggattcttc ccaaaatgca gcaatcgaac aagcgttaaa acttgcagac
    66421 aagccttata aaatggaatt caaaggcgta tatgtcatga gtgtagagaa aacatcgaat
    66481 ttctttggca agctttcagt tggagataca gtaacaaaag tagacgggaa aagctttcaa
    66541 agtacagaag catttatgga ttatgtaaaa agccaaaaag ttggacaaac aatcgaaatc
    66601 agttatttgc ataatggtga agaaaaaaca gcttctggtg atctgatcga gttaccaaca
    66661 gataaaaagg caggaatagg tatcacgctt actgaccata ccgagatcga atcagataca
    66721 gatgttcgta ttaattctgg ctctatcggt gggccatcag cgggattgat gttcacttta
    66781 gaaatctatg aacaagtcac tggtaaaaac ttgcgacatg gtaagcaaat tgcaggaact
    66841 ggaacgatca acagtgaagg agaagttggc cgaatcggag gaatcgataa aaaagtggca
    66901 agtgcggata aagctggcgt agagattttc tttgcaccag atgatacgat ttcagacgat
    66961 gttaagaaag aatatcctga aataaaaacc aactacgaag aagcaaaagc tgccgctaaa
    67021 aaattgaatt cctcaatgaa aatcgtacca gtaaaaacag tacaagaagc gcttgactat
    67081 ctagagaaaa tgaaatgaaa ctaaataatt aaagaggggt tgtgacacga gttctgtcac
    67141 aacccctctt tttcgtcaaa aatcttcacg ataaaaataa aaacaaaaga aaaaattgac
    67201 gtaattagat gttgaaggga cgattttgcc agagctcact gtttcttcaa ttttaaatga
    67261 aaggagtaat gaatgatttt tactggtcat tctttgaaaa aagaacaatg atagaaaaaa
    67321 tcagcaagaa aatactagct tcacccaaat tgatcatttg gatgtctatg atagttctta
    67381 tcttttgtat cgcaagtggt tttttattat caaatttgct attttataga gaaacagaag
    67441 agactgctgc aaaagaaata ctttcttcgt ttagttccag tggagaagat ccatcagctg
    67501 aaggaaacga tgtagaagag gatgctcgtc caaaggtcat gtacaccgat atcaaaggaa
    67561 gtgtgaagga gcctggtatc tattcctttt cttcagaaga acgggtctat gatgtactaa
    67621 agcgtgcagg tggattatta gaagaagcgg atagcgatcg aatcaacttt tctgcgaaga
    67681 tagaagatca gcaagtccta tatatccctg ctgtaggtga agagctgcca gaacatcttg
    67741 atcagttggc atcctcggaa ggaaaacagc ctacagcaga ttccgagcct cccaaaataa
    67801 atatcaatac agccactcca tcagaacttc agcagattcc tgggatcgga tcagtcaaag
    67861 cgcaagaaat cattcgattt agagaagaaa acggatcctt ccagaaagtg gaagacctgc
    67921 aggagatttc tggtatcggt gaaaagacag ttgaaaaact aaaaaacttc gttacaatta
    67981 aatagaatga ttcaaaatcg actggcacga gcaataaatg gacgctaatg gatactaaga
    68041 ataatccaat tctaagagct tggcaggacg aggaggtagt atttttggat aggaaatagc
    68101 ttgattgttc gcaaagaaac attaaaaaaa ccaatgctga atgtctatct ccaaaataaa
    68161 atatctggga ttcatattat gaatacggct gtcagcggca ataacagtca agctctacga
    68221 gaacgctttg ccaaagatgt acttagctat acagcagata aagtatttat tctcattggg
    68281 acgaatgatc tagcagagca taaacaactt tctaaagaaa cgtaccaaaa aatctgcagt
    68341 ggatgatagt tcagctgaaa aaagactata gttctgatca tgctttcttt atcacgccac
    68401 cagcagtcga tgagacaaaa caaaaatatc ggaataacaa gttgatcaaa gaatatatct
    68461 ctgttctcac agaagtagca aaacgccatg attgtgaagt atcgattttt atacggaatt
    68521 tcttgaacaa atggattcga agaattttta taatgggcta atggatgacg gacttcattt
    68581 cggcagtgaa gggtaggatc ttttgtcaga caggatgatt cgttatattt aaagaatatt
    68641 ttgtttaagc aatgagtact ttttaatcaa cttgaaaaaa cggaggaata taaaacatgt
    68701 tagaaaaatc ttcaaaagca tgcgatacga ataaagaaaa agttactgat aagtcacata
    68761 atgaacgcat tccttgggac cagtacttta tggctcaggc agtactgtta tctttacgta
    68821 gtacgtgtac acgtttagaa gtaggagcga cactcgttcg agaaaaaagg atcattgctg
    68881 gcggctataa tggagcagtc agtggagatg tccactgcat agatgaaggg tgttacgtcg
    68941 tggatggaca ctgcttgcga acgatccatg cagagatgaa tgcactccta cagtgtgcaa
    69001 aacttggtat cccgacggaa ggttcagaaa tctatgtcac acattttcca tgtttggcct
    69061 gtacaaaggc tttgttgcaa gctggtgtga aagggatcaa ttatctccat gactatcgaa
    69121 atgatcctta tgcccaagcg ttgatcgaac aattaggtgt atctgtacac caagttgctt
    69181 tagactcaca gcatttttca aaacttcaaa atgaattaac aggaaaacat gtctagcgtt
    69241 ttagaaaggc atgttcgaaa tcggttgatt tttccggcaa ttacgtcgat gattatctgt
    69301 ttgttgtatt acactgacaa ttggggttat cgtttgcttc ttgccggaat ttttttatgg
    69361 ttttcgctaa aagaaggacg ttttatcgcg tacttgtgta ttttgtgtag cataacggta
    69421 tccatttctt ataggctaca agagtattca tttttagagg aaaaaacaac atctgcgcaa
    69481 attactgtat ttacagatac gattcgtgca aatggtaatt ttttgacaat ggaaggaagg
    69541 ttatcagaga ataaacaaaa gctccagctt tcttatcaag taaacacaga agcagaattg
    69601 aaaacatggc ttaacttccg aggaaaggga atagaattga ctgctgaagg cgagttcatc
    69661 tctccagcaa aaaagcggaa tctttataat tttgaccaag aagcttactt caggaaccat
    69721 agaatttctg gacggttcca aattcaaaag attgaacaga tcaccatgca aaatcactgg
    69781 cgaaactggc ttcagagaaa aagaggatct tttatctcct ttgtccaatc tgaatttccg
    69841 caaaaaacaa gtgtatatat taattcttta ttatggggct ataaagatgc aggattcaga
    69901 gaaccagaag aaatttttag ggagagtggt ttgctgcatc tgttcagtct atcgggtcta
    69961 cacatccaat tttatttagg gtggctgtat tatttatttc gacgtatcgg atggccacta
    70021 cacgtcagta ttattccgtt gagtctacta actatctgtt atgtttctat tgcaggaagt
    70081 tctatttctg ttttgcgtgc tagtttgctg tttttattgc gattgctagt caaattgctg
    70141 aataagcatt attccaccat ggacttattt gcagttgtct tttggcttct tttactattt
    70201 gatcctcgat ttctttttca tgcgggtgga cagcttagtt ttttcatgag ttttttgttt
    70261 atcctgattt cttttgatgg agattggttg aaaaaaacgg cctctcacgt cctgtttact
    70321 atgatcacga tgccgttgat tgtatggcat ttttatgagt ggcctatttt aggtagtctt
    70381 tttacattac tgattgcacc ggtattcaag tttctttttc ttcctggtgt gttatttctc
    70441 acactcttca atcgctggct gccggaaact ttacttttgc tgatagaaga gggattaatc
    70501 ttatttgagc gaataatcga tttttcttca gggtcgtctc tcattatagg acgtttgccc
    70561 cttgtgctat ctgggatgta tattttcgga ttactgattt gtatggatag gttgaaagaa
    70621 caacctgtga aacacttgtt ttatgttggt cttttttctt ttattttttt gactttgcca
    70681 tttttacgct tttcttcaac gatcgctttt atcgatgtcg gtcaaggaga cagtatcttt
    70741 ttgcaaagtc cttttcgaaa agaaacgatt ttgatcgata ctggaggtca gttacacttt
    70801 gaaagagaaa agtgggcgca aggtatgata cgtcctcctg ctgaaagaaa tatcgttcca
    70861 tatctaaaag gtcaggggat aagtgtaatc gataaactca tcttgacaca cgacgatacg
    70921 gatcatgtgg gagaattacc cacgttatct cagcatttta ctatcaaaaa aatttatatc
    70981 ggttggggcg ctggacgaaa tgagccatta caaaggcatt tatctgaagc tcaaaaaaat
    71041 ggtactgaga tcattgaaat caaacatggg gacaggatca gcggttatta tgatctttat
    71101 gtattgactc cttttgaaaa gggagaggga agaaatgaag attcgattgg tctatggatg
    71161 gaatataaca ataggcgctt tttattttta ggagatttga atcaagcaat ggaaaaacaa
    71221 ttgcttttga tttatcctaa tctgaaagcc gatgtagtca aattaggtca tcacggtagc
    71281 cgtacgtcaa gtaacacaga ttttctttcc catattgaag caaaacatgg gattatatcc
    71341 tgcggcgtaa ataatcgtta tggtcacccg cacagcgaag tattggagac actagaagaa
    71401 aatcagataa aaacatggcg aacggatcaa caaggaatga tcacctatcg ctggcatcca
    71461 gtttttcatc ctcatgggct agtggaaaca atgatagact agtaattctc atctgctcat
    71521 ggtaggataa tttttgaaag tggtgagtaa tttgagtata caagcagagt tacaaaaaat
    71581 acgtaaagaa aaacttgcat cttgttactt gattttagga acagaaaagt ttctccaaga
    71641 tcaagttcgg acagaaattg tcaaaaaaat ccaattagag ggcgaagatg acttaaattt
    71701 tttaagtttt gacatggaaa atgcaagttt agatgaggta gtagctgaag cagagacgtt
    71761 gccgtttttc ggagatcaac ggttagtatt cgtagagaat ccttattttt taacaggtga
    71821 aaaagtaaac aatggaatcg aacaaaatac tgatttattg acggcttatt tgaaagaacc
    71881 attagaatcg actgtattag tattctttgc gccatatgaa aagttggatg aacggaaaaa
    71941 agtaacgaaa caattgaaaa aaacagcaat tatcatcaat gtccaacagt tgaatgaaaa
    72001 agaagtacgt caatatctga tgaatacctt agagaattcc tcaatcaaaa tggaacgaag
    72061 tgcaattgat ttattcttga ggttgaccga cttagattta tccaaaatga tgagagagtt
    72121 acagaaattg gtcctttatg gacaaaatca acagcaaatc acggtaagag aagtagaaga
    72181 attagttcct aaaacgttag aacataatat ttttgacatg acccaatata ttttaaaagg
    72241 gaagacggaa caagctttgc gtttatacga agatttagtt atgcaagggg aagaaacaat
    72301 caaaattaat gcgattttgc tttctcaatt acgtttattt ttacagacaa aatttcttgt
    72361 aaagattggt tatcagcagg caaatattgc tgaaacattg aaaatccatc catatcgtgt
    72421 aaaacttgcc atgcaggaag taaaaaaatt cgatgaacat ttgctggtac agttgtttga
    72481 tcaattagtt gagatggatt atcaaatcaa aacgggacaa atcgaaaaag aattaagttt
    72541 tcaactattc gttttgcgca cagggcagtt gttaagaaat cgataagaag aaagacgagg
    72601 gcaaagcatg cgggaaggtc gtttgttttt gtcctttttt tgacaaataa aaaaatcggc
    72661 cgaagccgat tcttttattt agcgattttt ttgcttaaac gagatttgtc gcggttagct
    72721 ttgtttttgt ggattagacc ttttgattca gccatatcaa tagctttaac agcttcttta
    72781 tataacgcat ctacgttgtc agcacctgaa gctacagcat cttcaaattt tttgattgca
    72841 gtacgcatag cgcttgtttg agatgaattt ttcacattag cgttttcgct tgtacgaaca
    72901 cgtttgattg cagattcaat gtttggcatt agtttcacct ccgataactt aagttcttac
    72961 gcgtgttacc gcataattca acattcatta ttatacctaa aggcagcgtg ctttgcaata
    73021 tgaacatgac aagttttttt ccttaacagt cttttattag gatttttttt cagtaaaaac
    73081 ggatagtaca agctgaaaaa aatcaaaaag acgctattgt gggaggcaat agcgtcaaac
    73141 caaactagat ttttatttat ctatttaaac aaagtttgaa tgggaatgtt tggtactaag
    73201 ttattatata acaaagagaa ccgtttgcaa agtttttttt gaaaagggat acgattccct
    73261 gttgttcttt gtttttctat taagaaactg cagttatttt ataaccagta tcctttgatc
    73321 agtaaaggct attctggtgt accgattatt ttaatgtatt catcgatatt ttttatcaac
    73381 atttttttta tgaccaactg gttccgacgg ttccatttgc cacttacttc cagcacatat
    73441 ttatttaggg gcaaacgtaa gatatatttt gccaaatagc gatctttaag caggccattg
    73501 atcacacggt cctcaagctg caagttgatc ccagtcagca tcattggctg ttcttgtaaa
    73561 acgtacgtat caattaaaag accttcaaaa gtttccacaa gcgtcttcct ttcttttcaa
    73621 agtaacctga aaacaggcac taattcttcc attttgatat tcgttgaagt ggatgcgatc
    73681 attctttctt ttgtccactg taatctagta taacaaaaaa gagcagaaga gccaaaaaga
    73741 aaaaagagca tcgaattcta taggaagtct cattggcacg gcctaaatta ttacaaaaca
    73801 ttgattaaaa aaagcccctg catcgcagga gcatccccta tatcgtttta ataggtcaat
    73861 caaaaagcag tatcaaacac attttgtatc aaatcaggaa ataatagata agctaagccc
    73921 agaatcaaaa gtaccgctag aagaaaccag ccgattgttc ctatgaaata ctttaatttt
    73981 tcgaacattg tatcacctcg ttgtcagtat atcacggatc agtaaattgg gggtgttaag
    74041 aatctcctaa aatagacaaa atttgttcta ttttcctaaa gcaaatactt gtaagataca
    74101 gtaagtgata ccagaagcaa tgaccggtcc ggcggcgatt cctcttaaga agacaacacc
    74161 taaaatcgtg ccgaaaacaa gtgcaacagt gatttgtgga tcagaagcaa tcaatcctac
    74221 acccttggaa gataagacag ccactagccc accgcaaaaa acagctaccc agccaatagg
    74281 ggatttaaag gcttctaata gatcacgtag accgatttct cctgttgcga tagggattag
    74341 aatagccgct gtgatgatcg tcaccccaat attgattcct ttgccttgaa gccaagggaa
    74401 aaaggaacgg gaggctggta tgagcttcat aatcaaaaca aaagctgccg ctatcatcag
    74461 actttgattt ttagctaaaa ttgctacaag taaaataatt cctaaaaaaa gccaactttc
    74521 catgaaatat attcctcact ttcttcgaaa caatcataac atgtttttag aaagttacaa
    74581 aagtaggaat tcatccttca agacctattc ataagctgtt tttttcataa aataaacaaa
    74641 atcataaaaa aacactttgc ttatttgaca gaagacagcc gcgctttgta tagtggacaa
    74701 gacttacatt tttttgaaga atcagaaaga tcaggtaaag gtcttagtaa acgcaagcca
    74761 ttcagaataa ccaatattgt gcttccttcg tgtcctacaa ctccaagagg tagatttaaa
    74821 aattgcagga agttagaagc aatcaacaag agaataacaa gaatcgaaaa aataatattt
    74881 tgtttgatga tccgccgcat ttttaaagat agccgatgac tgtagacaaa tttatttaag
    74941 tcgcttttca ttaagacgat gtctgcgata tccatagcgg catctgtccc ttgccccata
    75001 gcgacaccta aagaagcggc tgctaaagca ggcgcatcat tgactccatc accaaccatc
    75061 gcatttactt ggtaaagttc attctctttt ttgactagtt gtgttttttc ttccggagta
    75121 cagcttgcat agtaatgttc aatccctact tgttcagcaa tggcctttgc tgtgccagaa
    75181 tggtcaccgg ttatcatact tgtatggatg ttttgggatt taaagtagga aattacttgt
    75241 tgggtatttg cttttggaat atctagcaga cctaaaacag caattaactg ctgatcttta
    75301 gaaagataaa tcacggtttt gccttgattt tccaaacgtt cgatcatttc cgcaatctct
    75361 ttgctgatta tcatcgtctc aggatcatat gcgtgcttgc caactttcca ttgcgcacct
    75421 aaataggtag tttgtaatcc aaaaccagta atttcttcta ttggtaagta ttggatttct
    75481 tcaggtattg tgcaatcgaa atattgcaaa atcgcatgag caagtggatg cgtcgttttt
    75541 tgttccatag caacaagaag ttgttgtgcc aaatcctttt catcaaagaa aaagctgtca
    75601 gttacaactg gttttccttt agtgagcgtt cctgttttat caaaggcaat cgcttttaat
    75661 tcagaaagct tttctaaatg gataccgcct ttgattaaaa tcccattttt tgcagaattt
    75721 gaaagagcag ctagagaagc tggtgtagca gatgcgacaa gcgcacaagg agaagccaca
    75781 actaataata ccattcctcg ataaaagctt tcatcccaac tccaacctag gaaaaagtgg
    75841 gggagaagga tcattagagg aacagcaagc aaaatcaatt ttacataatt attttcgatt
    75901 cgttcgataa atgaagctgt ttgagttggc gtattctgcg cttcttctac taattggata
    75961 atcttagcaa agacagtttc ggaactcgtt tttgttactc gaatcgtgat gggatttcct
    76021 tgattcagcg ttcctgcata catctcatcg cctaaatatt tttctacagg cacagattca
    76081 ccgcttaatg cagactcatc gatcgttgcc tgtgtgcttt ctaaaaagcc atctatcgga
    76141 acagctgctc ctttagcgac aaataccaag ttatccacct ttagttgaga aacatctact
    76201 tcttgcattt gtccattttc ttttaataat tgggcttttt gtggttgaag attcatcaaa
    76261 gcagtaattt ctttttgact tttattagtt gtgtattcct ctaatgcacc gcttaaacaa
    76321 aagatgaatg tcaacattgc tccttcaaag taattaccga tcaaacaggc accaatagca
    76381 gctaaagcca tcaataaatc cacattcagt gtccgatcat tccacaattc tttcaagcct
    76441 tccgatgttt gtttatatcc accgatgata atggcactga tataaaaaag tggggtgatg
    76501 gtaagagaga atcggtcgaa gataaaaccg aagatcataa ataaaaggca gccgattgtt
    76561 gctgcaaaag cttttttctg attagtcatc gttattagac ctccttgtca aaacaaggat
    76621 agcataataa aaatgtaatt gataataata acagctaaat gagaacgata atggttatca
    76681 tttggtgatt aagcttgatg ttgtttttat tatttataat gattattatt aaagaaaata
    76741 aaaaaccaga acatttctca aataagagaa gtgttctggt tttttctaca ttgcaataaa
    76801 ccaataacca atcaaaatga taccaaggat aatacgatac cagccaaaag cggtaaagtc
    76861 gtttttcttc aaatagctta gtaagaattt gatagctaag acggaaacca caaaagatac
    76921 gaatgttcct acaagaagaa caacagtttc ttccattttg aatgaattcc cttcagctaa
    76981 atatttgacg atcttcaagc cgcttgcgcc aaacatgaca ggaatcccta agaaaaatga
    77041 aaactctgta gcgacaaaac gcgaagcacc aatcaagata gatcctagga tcgttgcgcc
    77101 agaacgggat gttccgggaa caagtgccaa gacttggaat aacccaacaa gaagagctgc
    77161 ttggtacgta aagtcattca gagaagtcca acgaggtgtt ttgtttttgt tgcgtttttc
    77221 gacaataata aaggcaatac cgtaaacgat caaaacaatg gcaactggta agaacttgtg
    77281 gaaatttgct tctaaccaat catccaaagg caaaccaatg atgatggctg gtatgcaagc
    77341 aacgatcact ttaaaccaaa gtgtccacgt atcttttttt tctaccgttg atttacttgg
    77401 agaaaatggg tttaacttgt gaaaataaag aacgacgaca gccaagatcg cccctaattg
    77461 gataacgaca ttgaacatcg acataaattg tgaactggca tccagtttga tgaattcatc
    77521 tgctaggatc aaatgaccag tactactgat gggcacccat tccgttattc cttcaataat
    77581 accgagaatc actgctttga taatatttgc aaaaaacata aattccttcc ttcccaatta
    77641 agatacatct tatagtatac cgttattttt tgagaaaccc aatctgtttt ttaatattaa
    77701 gaaaaacttg agaaataaag cagataagta cacgaagaga aaaaagaaga caaagccctc
    77761 gttcagactt tgccttttat gattctctgg taaaaattaa aatatcccca ttatagaaac
    77821 gagtcgcgac tatgtgtttt cccgttatcg atataagacg tatcattgat gccgtggata
    77881 gaaaatcgac cgtttgcata agtgaccttt gttacgctgc catttaaaag cccagcacga
    77941 acaggctgtt taggatcgat cagattaagc aaaaaggcga tcgtcaaacc atgagatacg
    78001 actaaaacat ttccaccacc atttttttcg cagtgatggg cgatatcttc aaatcctgtc
    78061 catacacggt ctcgcaatgt ttcataagtt tccgcccacc cagcggtatc taagttgtat
    78121 acagcattag caatttgttc aaaagaaact tctgtggtaa acatttcatc atatgtttta
    78181 aaattcaata cacgagggat cacaccccac atttccatgt catatccacc ttcaagagac
    78241 ccgaaacacc attctctaat ccttttttca ataaaataag gaatttcttt tcccttagaa
    78301 tgttctccta gaataatacg ggcagtttcg attgcacgac cactgtcact agaataagca
    78361 aatgaaaagt cgacattttt taacccgcga cctaaataat gaatgccttc ttgtccttgc
    78421 tttgtgaggg gtgtatcaca ccagccttgt actcgttcaa ttgtattgaa catcgttttt
    78481 ccgtgtcgta cgatataaag tgtagtttct gtcattttat tctcctccta agtcgtttta
    78541 acgattgaaa aaaggatttg tccttttttc ctgttcaatc gtcgttgcat cgccatgtcc
    78601 tggatagact gcaaattcat caggtaatac aaacagctgg gtccgaatac tatgaagtaa
    78661 ttgttctaaa ttccctgtat acagatcggt tctaccgata cttcctctaa acagggcgtc
    78721 gccagaaacg acaaaatcat caaaaataaa gctgacgctt cctatagaat gccctggggt
    78781 agggacgacg cgaaaagaca tgtttcctaa agtataagtt ttcatttcaa attcatattc
    78841 tgcaggcgag acaataacat cagcaatatc atcatgtcta ccgagtccag aaagattcaa
    78901 aatcggatca cctagccatt tttgctctag tgggctgaca taaactggga tttgataata
    78961 cgcgcgtaaa ggttccactg caccgatatg atcgtagtga gtatgggtaa gcaaaatcgc
    79021 taccggctgt tggtttgttt ttttgatttc ttgtttgatt cgttccgcat cttctccagg
    79081 gtcaatgatc aaaagtgctt cttcgttgta gaccaaataa cagttttctt caatcattcc
    79141 tgtttttaat ctttcgatat gcatgtgcat tcctccttga tagccaaaac ttctttcatc
    79201 cattagtata acgcattcat tgctaggaaa caaaaacagg tacttatttc tctttactta
    79261 tctgaattat cagactatat gaaaagtatt tggatattct aaagagaagg aaagtaagtt
    79321 ttcatagcat tttaatatgt ccttgttaca ttagattcat ccaaaaatcc aaattctata
    79381 tcctatatcc ctgcctaatc agcagggtgt ttttttatgt ttggaaagag agctcttttt
    79441 gctaaactag gttttttcag gtaatcttag agagaaagag gtggtggaaa tgatcaaaca
    79501 gtcaaaaata tctgtgcggc acttagtaga atttattttg cgacgtggaa gtatcgacaa
    79561 tcgtaaaaaa agtaaccata ctgcattaga aggagcgaga atccaccgca agctccaaaa
    79621 agatgcggga gaaaactatg aaaaagaagt ctttttaaaa acaacagttc aattagatga
    79681 atattacctg atcgttgaag gccgtgcaga cggtattttc aaaagagacg gtatttatta
    79741 tatagatgaa atcaaaacct ccgaaccacg atttgaagat ttagaaccag aacaagtgga
    79801 acttttcttt catcaagcaa gggtgtatgc ctatatctat agtcaagaac atgatttaca
    79861 agaaataaat ctgcaattga cttacttcca gacggcagaa gaagtgatca cgagaaaggt
    79921 tgaacatcag acaagagagc agttagaaac tttttttaaa aagctgactg aagattataa
    79981 agaatggctt gtttttcaag aaaactggcg cactgtacgc aatgcctctt tgatggcttt
    80041 gaaattcccc catgatgagt ataggaaagg tcagcgtgaa ctagcggtag ctgcttataa
    80101 aacgatccgt acgaaacaga aattgtttgt agaagcacct accggaacag gaaaaacaat
    80161 ctctacgtta ttccccgctt tgaaagctgt aggggaagaa gagggagaaa agatctttta
    80221 tctaacggct aaaacaataa ctagacaagt agctgaagat gctatgacag cattaaaaga
    80281 tacaggagct gaagtaaaaa gtgtcacttt gacggcgaaa gacaagatct gctttttaga
    80341 tgagacgacc tgtaatccag atcagtgccc atatgccaat ggttattaca atcggattaa
    80401 tgaaggttta tgggatcttt tgaatcatga gaatcagatc actcgtgaag tcatcgaaac
    80461 ttatgcaaga aagcatacac tttgtccttt cgaactatca ttagatgtca gtatctggtg
    80521 tgacgtaatc attggggatt acaattattt atttgatcca actgtttatt taagacgttt
    80581 ttttgaagat gaaaaaaacg aggactatct gtttttgatt gacgaagcac ataatttggt
    80641 gaatcgttcc cgagagatgt attcggcaga actatcttat gaaaaaacga aacgaagtaa
    80701 ggaagctata ccaaaggaat tcaaaaaact tcatcgccgt ttcaacaaac tattaaaaga
    80761 atttgattcg atccgagaaa tagcaaaaga agatcattgg gattatcatc atcaaaaagc
    80821 accggctgaa tctttagtaa aggcaggtta tcaattaagc gaaaaaatta aagaatggct
    80881 ggcagaattt cctgagcacc catcacaaga acaattgctt ccttattatt ttgatttgct
    80941 tcattttttg aaggtcagtg aattttatga tgatcactac gaaacaacag tcgaaaaaac
    81001 gtatcgcgat ctgatagtaa aagagttttg tattgatcca agcttgtttc ttgagcagtc
    81061 gttggataaa ggaaaaagca gtattctttt ttctgctagt ttttcaccac tctcttatta
    81121 tcaggaaaca ctggggggac aaaaaagtct ggcttacaaa ctgccgagtc ctttcccaga
    81181 aggaaaccag caagttttca tcgcaaatta cctagagacg acttatcgaa aaagggaaca
    81241 cagtctggca aaattagtag agacgattca tgcttttgct gatggaaagg tcgggaatta
    81301 tttcgttttc tttccttctt atcaatattt agatcttgcg gtggaagcat tcagacagca
    81361 atatcccgac agcaatgtgc taatccaaga aacggacatg aatgaggaag aacgcgaacg
    81421 atttttaaca aaatttcaaa caaatcccgc tgaaacattg attggatttt gcgtacttgg
    81481 cgggattttt tcagaaggaa tcgatttgag aggggaccga ttgatcggca gtatgatcgt
    81541 aggtgtaggt ttgccgcaga tgaatcatga gcaggaactg atcaaatcat attatgatga
    81601 gaaggaacac cttggatttg cttacgctta tcagcttcct ggaatgaaca aagtcttgca
    81661 agctggtggt cgagtgattc gtggcatggc ggatcaagga atcgttgtat tggcagatca
    81721 acgattttct agtttttctt atcgacgttt attcccacaa cattggcaaa cagcaagaga
    81781 agtacgaagt gttggggaat tggaagaagg aatacagcgt ttttggttat caaaagaagc
    81841 agtaaatcaa aaaaacgagg aatgacagac gtcagcctcg ttttttgatt aacgatagtt
    81901 agtgaattgc aactcgattg gtaagtcaag tttacgtaat aaagcaatca cagcttgtag
    81961 atcatcacgg ttcttacctg tcactctaat ctgatcttct tggatttgtg cttttacttt
    82021 cagtttttca tttttgatag ctgtagtgat tttcttcgcg ttttcacgat cgattccgtt
    82081 gaccaaatcg gcagtttgtc gagctttgcc acctagagcg tgttctgatt cggaaaaatg
    82141 gatatttttg attggcacat ttcttttgat cagcttacca aataatacat ctttgatctg
    82201 ttcgattttg aaatcatcat cgctcaatac aactagattg ctgttctcta atttgatttc
    82261 tactgtagaa tccttgaagt caaagcgatt ggacaattct tttgttgttt gctgaatcgc
    82321 attttttact tcttctgtat tgacttctga tacaatgtcg aagctagcat cttttgccat
    82381 aggaaccctc ctgatataca tataaatatt taccatacat ctatcttatc ataggattag
    82441 ggcagattct tacctgtttg ctaaaattct tctcatttga gttcgaagta ttttatttta
    82501 atagataaac tgttattctt acatttggaa taccaaagta ggggagaggt gcttgtgagt
    82561 aaaattatga ctgcgtatca taaaaatgaa agattaaaga aaatagtggt tattttgata
    82621 accggattga ccgctgcggt cgctttaaat tattttttga ttccagccaa tgtcttttct
    82681 gcagggatga atgggatcgc tcaaatcatt tcctcgcttt tatatgaatg gtttcatatc
    82741 aagatagaca caggaacatt tatttttctt ttgaatatcc ctgtgtttgt attagggttt
    82801 ctcaaagtag gaaaacgagc aacgatcctt agttttgtga atgttgtatg tgtatcggtg
    82861 atgacgatgc tgcttccagt cggacagatc actgataata ttttgatgaa tgccctagta
    82921 ggcggtgttt tattaggtct tggcgtagga ttatctttaa aaatgggctt tacaactggt
    82981 gggatggata tcatctctct tgtactttca caaacaactg gaaaaacagt cggaaactac
    83041 atgctgattc taaatggtat cattgtagtc atcgcaggct tcttctttaa ctgggaaagt
    83101 gccttgtata cgattatttc catttatgca atgactcaag taattgatgc catccacacg
    83161 agtcatcaaa aagtaacagc aatgatcgtt accgtcaagc cagaagaggt aacagaagaa
    83221 ctagcaaaac ggatggtacg tggaatgaca ttactgccgt ctgtcggtgg ctattcaaaa
    83281 aaacaaggga acatgatcat gatggtcatc acccgctacg aaatgtatga tcttgatcag
    83341 atcgttcatg aaatcgacga cgatgcattt atcaatattt taccaactca ttcagtattt
    83401 ggccggtttg caaatgaaaa cgaacaaaaa atgtatcgaa caactggcgt attgccagaa
    83461 ataaaaaatc gttcacaaaa aaaatgagga atcaggttta ttttagaata aatttaatct
    83521 attacatcta ataagaacat ttttataaat ttaaacgaga atcttacttc taaattctca
    83581 tttacaagca gctaaaaaaa gagtatgata aataaaaatc gtgttaagga gtgtcgtacg
    83641 atgagcgaag caaaccaaga acggtctgga caagaaatag aactaatcaa agaacgtatt
    83701 cttgctgcct tggaaatggt gattgatcct gaattaggaa tcgacatcgt caatttaggc
    83761 ttgatttatg atatagaatt caatcctgaa aatggagaaa cagtcattaa gatgactcta
    83821 acaactatgg gctgtccatt agcagatatt ttaacagaat ctatccatga cgcattaaaa
    83881 gaagtgccag aagtaacgaa agcagaagtc aaactagtct ggtatccagc atggacgaca
    83941 gataagatga gccgttatgc acggattgcg ttggggatac gatagaaatc ttggctgact
    84001 agctatgaga agcaaatagg aaaaacaaaa aagcctttta tcctttctag aagaaaagag
    84061 ataaaaggtt tctttgttta taaaattttg tctgctatat tataagttaa ttaa
//
LOCUS       DAZULR010000005        77413 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.005, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000005 DAZULR010000000
VERSION     DAZULR010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 77413)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 77413)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..77413
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.005"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(178..1743)
                     /gene="guaA"
                     /locus_tag="ACG8ZV_000343"
     CDS             complement(178..1743)
                     /gene="guaA"
                     /locus_tag="ACG8ZV_000343"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HFS4995713.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(1802..2725)
                     /gene="coaA"
                     /locus_tag="ACG8ZV_000344"
     CDS             complement(1802..2725)
                     /gene="coaA"
                     /locus_tag="ACG8ZV_000344"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HFS4995714.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            2921..3526
                     /locus_tag="ACG8ZV_000345"
     CDS             2921..3526
                     /locus_tag="ACG8ZV_000345"
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFS4995715.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            3834..4850
                     /locus_tag="ACG8ZV_000346"
     CDS             3834..4850
                     /locus_tag="ACG8ZV_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFS4995716.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            4991..6292
                     /locus_tag="ACG8ZV_000347"
     CDS             4991..6292
                     /locus_tag="ACG8ZV_000347"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HFS4995717.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            6338..7000
                     /gene="deoC"
                     /locus_tag="ACG8ZV_000348"
     CDS             6338..7000
                     /gene="deoC"
                     /locus_tag="ACG8ZV_000348"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HFS4995718.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            7021..7419
                     /locus_tag="ACG8ZV_000349"
     CDS             7021..7419
                     /locus_tag="ACG8ZV_000349"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HFS4995719.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            7485..8567
                     /locus_tag="ACG8ZV_000350"
     CDS             7485..8567
                     /locus_tag="ACG8ZV_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HFS4995720.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            8779..10341
                     /locus_tag="ACG8ZV_000351"
     CDS             8779..10341
                     /locus_tag="ACG8ZV_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4995721.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            10334..11467
                     /locus_tag="ACG8ZV_000352"
     CDS             10334..11467
                     /locus_tag="ACG8ZV_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4995722.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            11467..12423
                     /locus_tag="ACG8ZV_000353"
     CDS             11467..12423
                     /locus_tag="ACG8ZV_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4995723.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            12522..13688
                     /gene="deoB"
                     /locus_tag="ACG8ZV_000354"
     CDS             12522..13688
                     /gene="deoB"
                     /locus_tag="ACG8ZV_000354"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HFS4995724.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            13712..14530
                     /locus_tag="ACG8ZV_000355"
     CDS             13712..14530
                     /locus_tag="ACG8ZV_000355"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFS4995725.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            14547..15254
                     /gene="deoD"
                     /locus_tag="ACG8ZV_000356"
     CDS             14547..15254
                     /gene="deoD"
                     /locus_tag="ACG8ZV_000356"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFS4995726.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(15552..16238)
                     /gene="gpmA"
                     /locus_tag="ACG8ZV_000357"
     CDS             complement(15552..16238)
                     /gene="gpmA"
                     /locus_tag="ACG8ZV_000357"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HFS4995727.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(16410..16991)
                     /locus_tag="ACG8ZV_000358"
     CDS             complement(16410..16991)
                     /locus_tag="ACG8ZV_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFS4995728.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(17124..17807)
                     /gene="rpiA"
                     /locus_tag="ACG8ZV_000359"
     CDS             complement(17124..17807)
                     /gene="rpiA"
                     /locus_tag="ACG8ZV_000359"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HFS4995729.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            18126..18539
                     /gene="rpsL"
                     /locus_tag="ACG8ZV_000360"
     CDS             18126..18539
                     /gene="rpsL"
                     /locus_tag="ACG8ZV_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HFS4995730.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            18623..19093
                     /gene="rpsG"
                     /locus_tag="ACG8ZV_000361"
     CDS             18623..19093
                     /gene="rpsG"
                     /locus_tag="ACG8ZV_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HFS4995731.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            19187..21274
                     /gene="fusA"
                     /locus_tag="ACG8ZV_000362"
     CDS             19187..21274
                     /gene="fusA"
                     /locus_tag="ACG8ZV_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HFS4995732.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            21446..22633
                     /gene="tuf"
                     /locus_tag="ACG8ZV_000363"
     CDS             21446..22633
                     /gene="tuf"
                     /locus_tag="ACG8ZV_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HFS4995733.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            23040..23348
                     /gene="rpsJ"
                     /locus_tag="ACG8ZV_000364"
     CDS             23040..23348
                     /gene="rpsJ"
                     /locus_tag="ACG8ZV_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HFS4995734.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            23379..24008
                     /gene="rplC"
                     /locus_tag="ACG8ZV_000365"
     CDS             23379..24008
                     /gene="rplC"
                     /locus_tag="ACG8ZV_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HFS4995735.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            24036..24659
                     /gene="rplD"
                     /locus_tag="ACG8ZV_000366"
     CDS             24036..24659
                     /gene="rplD"
                     /locus_tag="ACG8ZV_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HFS4995736.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            24659..24949
                     /gene="rplW"
                     /locus_tag="ACG8ZV_000367"
     CDS             24659..24949
                     /gene="rplW"
                     /locus_tag="ACG8ZV_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HFS4995737.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            24988..25821
                     /gene="rplB"
                     /locus_tag="ACG8ZV_000368"
     CDS             24988..25821
                     /gene="rplB"
                     /locus_tag="ACG8ZV_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HFS4995738.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            25864..26142
                     /gene="rpsS"
                     /locus_tag="ACG8ZV_000369"
     CDS             25864..26142
                     /gene="rpsS"
                     /locus_tag="ACG8ZV_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HFS4995739.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            26165..26512
                     /gene="rplV"
                     /locus_tag="ACG8ZV_000370"
     CDS             26165..26512
                     /gene="rplV"
                     /locus_tag="ACG8ZV_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HFS4995740.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            26526..27182
                     /gene="rpsC"
                     /locus_tag="ACG8ZV_000371"
     CDS             26526..27182
                     /gene="rpsC"
                     /locus_tag="ACG8ZV_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HFS4995741.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            27185..27619
                     /gene="rplP"
                     /locus_tag="ACG8ZV_000372"
     CDS             27185..27619
                     /gene="rplP"
                     /locus_tag="ACG8ZV_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011375443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HFS4995742.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            27609..27797
                     /gene="rpmC"
                     /locus_tag="ACG8ZV_000373"
     CDS             27609..27797
                     /gene="rpmC"
                     /locus_tag="ACG8ZV_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HFS4995743.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            27822..28088
                     /gene="rpsQ"
                     /locus_tag="ACG8ZV_000374"
     CDS             27822..28088
                     /gene="rpsQ"
                     /locus_tag="ACG8ZV_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HFS4995744.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            28146..28514
                     /gene="rplN"
                     /locus_tag="ACG8ZV_000375"
     CDS             28146..28514
                     /gene="rplN"
                     /locus_tag="ACG8ZV_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HFS4995745.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            28551..28859
                     /gene="rplX"
                     /locus_tag="ACG8ZV_000376"
     CDS             28551..28859
                     /gene="rplX"
                     /locus_tag="ACG8ZV_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HFS4995746.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            28887..29426
                     /gene="rplE"
                     /locus_tag="ACG8ZV_000377"
     CDS             28887..29426
                     /gene="rplE"
                     /locus_tag="ACG8ZV_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HFS4995747.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            29445..29630
                     /locus_tag="ACG8ZV_000378"
     CDS             29445..29630
                     /locus_tag="ACG8ZV_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HFS4995748.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            29666..30064
                     /gene="rpsH"
                     /locus_tag="ACG8ZV_000379"
     CDS             29666..30064
                     /gene="rpsH"
                     /locus_tag="ACG8ZV_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HFS4995749.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            30096..30632
                     /gene="rplF"
                     /locus_tag="ACG8ZV_000380"
     CDS             30096..30632
                     /gene="rplF"
                     /locus_tag="ACG8ZV_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HFS4995750.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            30793..31149
                     /gene="rplR"
                     /locus_tag="ACG8ZV_000381"
     CDS             30793..31149
                     /gene="rplR"
                     /locus_tag="ACG8ZV_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HFS4995751.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            31170..31670
                     /gene="rpsE"
                     /locus_tag="ACG8ZV_000382"
     CDS             31170..31670
                     /gene="rpsE"
                     /locus_tag="ACG8ZV_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HFS4995752.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            31685..31864
                     /gene="rpmD"
                     /locus_tag="ACG8ZV_000383"
     CDS             31685..31864
                     /gene="rpmD"
                     /locus_tag="ACG8ZV_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HFS4995753.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            31908..32348
                     /gene="rplO"
                     /locus_tag="ACG8ZV_000384"
     CDS             31908..32348
                     /gene="rplO"
                     /locus_tag="ACG8ZV_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HFS4995754.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            32348..33643
                     /gene="secY"
                     /locus_tag="ACG8ZV_000385"
     CDS             32348..33643
                     /gene="secY"
                     /locus_tag="ACG8ZV_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HFS4995755.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            33705..34352
                     /locus_tag="ACG8ZV_000386"
     CDS             33705..34352
                     /locus_tag="ACG8ZV_000386"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_function: GO:0019205 - nucleobase-containing compound
                     kinase activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HFS4995756.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            34543..34761
                     /gene="infA"
                     /locus_tag="ACG8ZV_000387"
     CDS             34543..34761
                     /gene="infA"
                     /locus_tag="ACG8ZV_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HFS4995757.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            34794..34910
                     /gene="rpmJ"
                     /locus_tag="ACG8ZV_000388"
     CDS             34794..34910
                     /gene="rpmJ"
                     /locus_tag="ACG8ZV_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HFS4995758.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            34928..35293
                     /gene="rpsM"
                     /locus_tag="ACG8ZV_000389"
     CDS             34928..35293
                     /gene="rpsM"
                     /locus_tag="ACG8ZV_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HFS4995759.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            35321..35710
                     /gene="rpsK"
                     /locus_tag="ACG8ZV_000390"
     CDS             35321..35710
                     /gene="rpsK"
                     /locus_tag="ACG8ZV_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HFS4995760.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            35790..36728
                     /locus_tag="ACG8ZV_000391"
     CDS             35790..36728
                     /locus_tag="ACG8ZV_000391"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HFS4995761.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            36756..37136
                     /gene="rplQ"
                     /locus_tag="ACG8ZV_000392"
     CDS             36756..37136
                     /gene="rplQ"
                     /locus_tag="ACG8ZV_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HFS4995762.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            37408..38247
                     /locus_tag="ACG8ZV_000393"
     CDS             37408..38247
                     /locus_tag="ACG8ZV_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HFS4995763.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            38223..39092
                     /locus_tag="ACG8ZV_000394"
     CDS             38223..39092
                     /locus_tag="ACG8ZV_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HFS4995764.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            39082..39879
                     /locus_tag="ACG8ZV_000395"
     CDS             39082..39879
                     /locus_tag="ACG8ZV_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HFS4995765.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            40082..40828
                     /gene="truA"
                     /locus_tag="ACG8ZV_000396"
     CDS             40082..40828
                     /gene="truA"
                     /locus_tag="ACG8ZV_000396"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HFS4995766.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(41283..43952)
                     /locus_tag="ACG8ZV_000397"
     CDS             complement(41283..43952)
                     /locus_tag="ACG8ZV_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HFS4995767.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(44190..44378)
                     /gene="rpmB"
                     /locus_tag="ACG8ZV_000398"
     CDS             complement(44190..44378)
                     /gene="rpmB"
                     /locus_tag="ACG8ZV_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HFS4995768.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            44648..45010
                     /locus_tag="ACG8ZV_000399"
     CDS             44648..45010
                     /locus_tag="ACG8ZV_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFS4995769.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            45062..46744
                     /locus_tag="ACG8ZV_000400"
     CDS             45062..46744
                     /locus_tag="ACG8ZV_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HFS4995770.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            46861..48897
                     /gene="recG"
                     /locus_tag="ACG8ZV_000401"
     CDS             46861..48897
                     /gene="recG"
                     /locus_tag="ACG8ZV_000401"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HFS4995771.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            48946..49947
                     /gene="plsX"
                     /locus_tag="ACG8ZV_000402"
     CDS             48946..49947
                     /gene="plsX"
                     /locus_tag="ACG8ZV_000402"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HFS4995772.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            50069..50311
                     /gene="acpP"
                     /locus_tag="ACG8ZV_000403"
     CDS             50069..50311
                     /gene="acpP"
                     /locus_tag="ACG8ZV_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFS4995773.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            50579..51583
                     /locus_tag="ACG8ZV_000404"
     CDS             50579..51583
                     /locus_tag="ACG8ZV_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4995774.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            51584..52528
                     /locus_tag="ACG8ZV_000405"
     CDS             51584..52528
                     /locus_tag="ACG8ZV_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4995775.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            52528..53490
                     /gene="opp4B"
                     /locus_tag="ACG8ZV_000406"
     CDS             52528..53490
                     /gene="opp4B"
                     /locus_tag="ACG8ZV_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HFS4995776.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            53517..54431
                     /locus_tag="ACG8ZV_000407"
     CDS             53517..54431
                     /locus_tag="ACG8ZV_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4995777.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            54457..56238
                     /locus_tag="ACG8ZV_000408"
     CDS             54457..56238
                     /locus_tag="ACG8ZV_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HFS4995778.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            56586..57272
                     /gene="rnc"
                     /locus_tag="ACG8ZV_000409"
     CDS             56586..57272
                     /gene="rnc"
                     /locus_tag="ACG8ZV_000409"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HFS4995779.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            57292..60873
                     /gene="smc"
                     /locus_tag="ACG8ZV_000410"
     CDS             57292..60873
                     /gene="smc"
                     /locus_tag="ACG8ZV_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HFS4995780.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIETALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            60882..61691
                     /locus_tag="ACG8ZV_000411"
     CDS             60882..61691
                     /locus_tag="ACG8ZV_000411"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFS4995781.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            61702..62700
                     /gene="ftsY"
                     /locus_tag="ACG8ZV_000412"
     CDS             61702..62700
                     /gene="ftsY"
                     /locus_tag="ACG8ZV_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HFS4995782.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            62887..65154
                     /gene="gshAB"
                     /locus_tag="ACG8ZV_000413"
     CDS             62887..65154
                     /gene="gshAB"
                     /locus_tag="ACG8ZV_000413"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004357 - glutamate-cysteine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HFS4995783.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(65243..65695)
                     /locus_tag="ACG8ZV_000414"
     CDS             complement(65243..65695)
                     /locus_tag="ACG8ZV_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HFS4995784.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            65845..66795
                     /locus_tag="ACG8ZV_000415"
     CDS             65845..66795
                     /locus_tag="ACG8ZV_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFS4995785.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            66788..67747
                     /locus_tag="ACG8ZV_000416"
     CDS             66788..67747
                     /locus_tag="ACG8ZV_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFS4995786.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            67744..68499
                     /locus_tag="ACG8ZV_000417"
     CDS             67744..68499
                     /locus_tag="ACG8ZV_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4995787.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            68522..69475
                     /locus_tag="ACG8ZV_000418"
     CDS             68522..69475
                     /locus_tag="ACG8ZV_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HFS4995788.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(70119..70415)
                     /locus_tag="ACG8ZV_000419"
     CDS             complement(70119..70415)
                     /locus_tag="ACG8ZV_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HFS4995789.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            70770..71126
                     /locus_tag="ACG8ZV_000420"
     CDS             70770..71126
                     /locus_tag="ACG8ZV_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFS4995790.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            71136..72035
                     /locus_tag="ACG8ZV_000421"
     CDS             71136..72035
                     /locus_tag="ACG8ZV_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFS4995791.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            72554..73282
                     /locus_tag="ACG8ZV_000422"
     CDS             72554..73282
                     /locus_tag="ACG8ZV_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFS4995792.1"
                     /translation="MKKEIVLTAAIMLFSMVASTTFVSATEVYPKEYNTEGTITFEAG
                     DEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYAA
                     ADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAVS
                     LVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSVP
                     GKSVKLAQQYSTKLVWTLEDTPNN"
     gene            73427..75454
                     /locus_tag="ACG8ZV_000423"
     CDS             73427..75454
                     /locus_tag="ACG8ZV_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HFS4995793.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRIDIPVENQRIGTFEGKLSWILADVPGN"
     gene            75562..76659
                     /locus_tag="ACG8ZV_000424"
     CDS             75562..76659
                     /locus_tag="ACG8ZV_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HFS4995794.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            76966..>77413
                     /locus_tag="ACG8ZV_000425"
     CDS             76966..>77413
                     /locus_tag="ACG8ZV_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4995795.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRKL"
BASE COUNT        25289 a        13938 c        16678 g        21508 t
ORIGIN      
        1 ttctcggaaa acagttcgtt tttcgagaac ttctttttat gataagaatg aaacaaatta
       61 acttatatta tagtctcttt tggtagggaa ccatcttatt tttaatgaaa atcaagcatt
      121 ttagctattg aagaatgttg atttataggg attccccctc catattatgt tggctcttta
      181 ttcccactcc actgttgctg gtggtttaga agtgatgtca tacacgatac ggttgacgtg
      241 ggctacttcg tttacgatac gtacagagat tttttgcaag acttcccatg ggatacgggc
      301 aaagtcagcg gtcattccgt cgattgaagt tacagcacgg ataccgactg tgtagtcgta
      361 agtacgtccg tcacccataa caccgacaga gcggatccct ggaagaacag tgaaatattg
      421 ccagatatca cggtcaagtc cagcagctgc gatttcttca cgcaagatag catcagattc
      481 gcgtacgatt tctagcttgt cttcagtgat ttcgccaaga acacgaatac caagaccagg
      541 accagggaat ggctgacgcc aaacgattga atcaggcatg cctaactgag tccctaattc
      601 acggacttcg tctttgaata atgtgtttaa tggttcgatc aattcaaatt gcatatcttc
      661 tggcagtcca cctacattat ggtgagattt gatcgtctgt gctgtttctg taccagattc
      721 gataacgtca gtatacaacg ttccttgtgc taggaaagag acgccttctt caccagcaag
      781 ttttgttgct tcgtcatcaa aaacatatac gaattcattc ccaatgattt tacgtttttg
      841 ttctgggtca gatacacctt tcaacttgtc taagaagcga tctcttgcat tgactttgat
      901 gatgttcaag ccgaattttc cgcctagact ttccattact tgttccgctt cgcctttgcg
      961 tagcagaccg tggtcaacaa agatagatgt caattggtca ccgatcgctt tttgtaaaag
     1021 aaccccaacg acactagaat caacgccacc tgaaagacca agcaagactt ttttgtcacc
     1081 aacttgttca cggatttttt ctacttgcat atcgataaag ttatccattg tccagttacc
     1141 ttcacagtga caaacatcaa aggcaaagtg gcgcagcaat tcgattccgt attcggaatg
     1201 acgtacttct gcatggaatt ggataccata aaaattacgt gttgtgtctt ggatagaagc
     1261 aatcggacaa tctttgcttg ttccgactgt ttcaaagcct tcaggaactt tagttaccaa
     1321 gtcaccatgg ctcatccata ctgtttgttg ttttggtgtt tctttaaaca agacagcttg
     1381 atcgcttgtt acttctaaca aggctttccc atattcgcgg tttttagcag gctctacgga
     1441 accgccaagt ttgtacgtga tcaattgcat accatagcaa atccctaata caggaatacc
     1501 taaattgaag atctcaggat cgatcccaaa tgcattctca tcatatacac tgtttggtcc
     1561 gccagaaaga atgattccct ttggattcat cgcttttact tcttctgcag taatgcggtg
     1621 gctcaataat tcggaaaaga ctccaagatc acgaatacgt cttgtgatca attggttata
     1681 ctgactaccg tagtctaata cgataatctt ttcaacgttc gtcatatcgg caacgtttgt
     1741 caaatttatt acccctatcc ctttaaattt tatctcaaaa tagtcaaact attttaaaat
     1801 gctaatattt tcgcatgaaa atcgaatcga tgatatgatt ttcagtttta tggagaatta
     1861 tatcggctct tcctcgtgta ggcaagatat attcctgtaa atttttcaaa ttcacatttt
     1921 tccatacatc ttttgccatt ttaaaggctt cttcacgatc tccgatagca aaacgataat
     1981 aataattctc tggattttgg aaagccgtat ccagtaacgc accaaaacga tccaaatacc
     2041 atttttcgat cagcacggga tcggcatcga catagacaga aaaatcaaaa aagtcgctga
     2101 cgtagatttg ctgattcgca ggtaattgaa gcgtattgat cccctcaacg atcaagatat
     2161 caggctgctg gatcaattcg tacttgtctg gaatgatatc atacacatca tgtgagtaaa
     2221 caggtacttt tatctcttcc tgaccagatt ttacacggtt caagaaatcg atcagcatct
     2281 ccatatcata actttcagga aatcctttac ggtccatgat tccacgctct tttaatatac
     2341 gatttggata aagaaatccg tcagtcgtga tcagctgaac gtttcttcgt ttgaaggtac
     2401 gagacaaaat cgtctgcagc agtctggctg ttgtactttt tccaacggct acacttccgg
     2461 cgatcccgat aataaaaggc ggtacttcta cgtatttatg aagaaataaa cctttactca
     2521 agaacaaaga ttcaaattct ttcatataaa gataaatcag atgagcaaga ggtacataga
     2581 tatctcgaac atcctgcatg gaaatgcggt cattcaaact tttgatatta tctagttcat
     2641 cttgtgtcaa aggtgcttgc ccattacgat aaaattctcg ccattcttct cttgccacac
     2701 ggtagtagtt cattggatca ttcatattag cctcctgcgt tctcccatca atggaactat
     2761 tttaacacaa aataaacgca aaccccacca cttaagagag attgccgatc tttttgtata
     2821 atctttataa tagaaagaaa cggagtctta ttcttgactt gcgcacggat acataaaagg
     2881 atagactgtt gtcatgaaag aaatgagaag gatggaagac atgacaaatc attactattc
     2941 tgaacgccca gatacggcgc acgattttga acaatgggct tttgagttaa aaggcagaac
     3001 ctttcaattt gtaacagatt ctggtgtatt ttcacgtgaa acagtggatt atggttcacg
     3061 tgtcctgatt gatgctttcg attgggaaga gttacctgat gaaggaaaga tcttagatgt
     3121 gggatgcggg tatggaccga ttgggttagc tttggcattt gcgacacagc ggtttgttga
     3181 aatggtcgac attaatgaac gagcggtaag tctagcgcaa ggaaacgcaa agcgtaacca
     3241 aatcgaacat gttgatatcc atcaatcgaa tatctatgaa gcagttcatg aagaaaccta
     3301 tgcagctatc gtaagcaatc cgccgatccg tgctggaaaa aaagttgtac atgaaatttt
     3361 gacaggcgca tatcctcggt tgaagaaggg cggtacactg acaattgtga tccagaagaa
     3421 acaaggagcg ccgagtgcgc aaaagaaaat ggaagaaaca tttggtaatg cagaaatcgt
     3481 cacaaaagat aaaggatatt atatcatcaa aagtgtgaaa gaataactag ctgaaaaata
     3541 gtggagcgac gaaagagtgg aactgggcgt gcatgtacgg gtacgtatca gttctttttt
     3601 tgttgagaag tttttaaaaa caaagaacta ttttttcttc aaaaagaaat agtaggaaca
     3661 gagtcgttgt tttttacgat aaaataaata agatacagaa cttgtataga aggctgccaa
     3721 gtcggtagat aaaggaggtt tttatcaaaa aacatacttt ccttttttct ctattctttt
     3781 cttgggggtt ttggtacact gatagggaat ttagatagaa gggagccaat aggatgaagc
     3841 tgaccatcag agatatcgca gaaatggcag gcgtatcagt aacaactgtc tcacagattt
     3901 tgaataacaa aggaagcaga tttagtgata agacaagaaa aaaagtgttg tcgatcgtga
     3961 atgaacatca ttataagccc gattatttcg cttcaaatgt gatcaatcga cattcaaaga
     4021 ccatcggaat gatcgtccct gatgtcactg atttcttctt ctccaaactg atcgaaggtg
     4081 tagagagcta tttgaatcct ttgggctatg tgatcatgtt atgcaattct cgtcatagcc
     4141 aagaaaatga gatcaagtat ttacaagagc tttcccaccg ctcagtggac ggaatcttgc
     4201 tggccacacc aaatatttta cctgagaaat atgcattaga cagcggtttt tatcaaaaaa
     4261 tgccaatcat tttaatcgat cgcggattga atcgtcggga taacggacgg cttatcgtaa
     4321 aggaatatga gggcgcctat caagctgttt cgctgtttat tgaaaatggc catacgaaga
     4381 tcggcatgct gaaggaaacc actggatact atcaattaga agaacgtttc aacggatatc
     4441 gtcatgcgct gaaagatcat ggcctgcctt ttaatgggaa atttgttgaa catggagagt
     4501 tgactgtcca aggtggatat actgcatcaa aaaaattact caaacataaa gatatcacgg
     4561 ctattttttg cgggaatgat gccatggcga tcggatgcta tcaggcgatc gatgaattgg
     4621 gcaaaaaaat cccagaagat atctcagtca taggattcga tggattaaag ctgtcagaat
     4681 acatgattcc gcaattgacg acagtgcagc agccaagttt tgatattgga ttttatgctg
     4741 cacgtttcct gatcgatacg atcgaatttc ctcaaagaaa agttccgaac aaagtgttcg
     4801 aaacaaaatt aattattcgt gagagcgtaa aagtattgac aaagggctaa ctcggcggta
     4861 tattgcttat gtaagcattt acaaaggcta gttagtgctt tttttatttt tagtaaacca
     4921 gtttactaaa gtggtttacc tttcctaaaa ataatgtata ataccgaatg aagacaagga
     4981 ggatcaggca atgcgaatgg tggatctgat tgaaaaaaag agggatggaa acgagctgtc
     5041 gaaagaggaa atcgagtaca tcgtcacgaa ctatacgaat ggaaagattc cagattatca
     5101 agtcagtgca ttattgatgg caatttttta tcaagacatg acaaatgaag aaatcacgaa
     5161 cttaacattg gcgattgcta attctggtga tgtcatcgat ttgagttctc ttgaaggaat
     5221 aaaggtagat aagcattcga caggtggcgt tggtgacacg accacattga ttttagcccc
     5281 cctagtagct agtgtcggag tgacagtggc taaaatgtct ggacgcggtc taggttacac
     5341 aggtggtaca ctagacaagc tagaagcaat tcccggattt cagatcgagc tttcggatga
     5401 agaatttgta cgcattgtta atgaaagtaa agtagcggta attggtcaat caggaaactt
     5461 ggcaccggcg gacaaaaaat tgtatgcctt gcgtgacgtc acagcgaccg ttgattctct
     5521 tccgctgatt gccagttcga ttatgagtaa aaaaatcgcg gcaggagcag atgcaatcgt
     5581 tttggatgtg accactggag acggtgcttt catgaagaac atcgaagatg caagacgtct
     5641 ggcaaagacc atgacgagca ttgggaaact ggctaaccga gaaacagtgg cggttatctc
     5701 agatatgtca gaacctcttg gcgaagctat cggaaatagt ctagaagttg tcgaggcaat
     5761 cgaaacatta caaggaaatg gtccagaaga tctagtagaa atgtgctacg ccttaggaag
     5821 ccaaatggtt gttcttgctg gcaaagctaa gacaaccgat gaagcaagaa cgttgcttca
     5881 agaagctctg gaatcaggta aagcgttagc aaaattcaaa gaaatgatcc aaaatcaagg
     5941 gggagaccca gcgatcgtgg aacatccaga acgaattttg actgcacgct acacaatgga
     6001 gcttcctgct aaacaaagcg gagttgtgtc aaaaatcgtg gcaaatgaat taggaattgc
     6061 tgcaatgatg ctaggtgctg ggcgtaaaac caaagaagaa gatattgatc acgctgttgg
     6121 attgaaactg cataaaaaaa ttggtgacac tgtgacaaaa ggtgagtcac tattgacgat
     6181 ctatagtaac gacgaagaaa tcacttctgt cattgaatta ttatataaaa atattgaaat
     6241 tggtgaatcg gcaatgaagc caacgttgat tcatgacatc atcacagaat aaaggaaaaa
     6301 agcggacttt accgttttaa agaaaagggg aaaagaaatg gaactaaacc gaatgatcga
     6361 ccatactatt ttgaaagcag acgcatctaa agaagctgtg atgcaaatta tcgaagaagc
     6421 aaaaaaatac catttttatt ctgtctgcat caatccagca tgggttgcgc tagcgaaaga
     6481 acaattacaa ggtgagccag tagccgtatg tacagtaatc gggtttcctc taggagcaaa
     6541 cacacccgag acaaaagcat ttgaaacaac agatgccatc aataacggtg cagatgaagt
     6601 cgatatggtc atcaatatcg gtgctttgaa atcaaaggat gatcaacaag tccaaaaaga
     6661 tatcgaagca gttgttgaag cagcaaaaga tcgtgcgctt gtcaaagtta ttattgaaac
     6721 atcgttatta gatagagaag aaatcatccg agcttgcgaa atagcaaaag ctgcaggcgc
     6781 tgattttgtc aaaacatcaa ctggtttctc aacaggcgga gcaaaggtag aggatgtccg
     6841 tttgatgcgt gaaactgtag gaccagaaat gggtgtcaaa gcttccggcg gtatccataa
     6901 cgaagaagaa gcaatggcaa tgatcgaagc tggtgctaca agaatcggaa caagcgcagg
     6961 agtagcaatc gtatctggtt caactggtga aggctattaa ttttttcaaa ggagaagctc
     7021 atggcagaac tcaaacaaga atggatcaac acagctattg aagcgttaga taaagcctat
     7081 gttccttatt cccattttcc ggtaggcgct tgtctcgtaa cggaatcagg caagatttat
     7141 caaggcatca acattgagaa tgcatcattt ggattaacga attgtgccga gcgcacagct
     7201 tttttcaaag cagtatctga aggagaaaaa acatttacgc atctagtcgt agcggggcac
     7261 acccccgatc ctatctctcc ttgtggtgca tgtcgacaag taatggcaga attctgttcc
     7321 cctgatatgc cggttacgct agtaggagac aatggtgtga cgaaggcaac gaccgttcgt
     7381 gcactgctgc cttatgcatt tactgaaaaa gatctataac tcatgttcat tcagtcagct
     7441 gactgttgaa aaataaaaca attattttag gaggctttac agaaatgaaa aaagcaaaat
     7501 tatttggttt aggtgctgtc gcactagcag cagggttatt tttaggtgca tgcggcaaca
     7561 acggctctac tgattcatcc ggtggcaaaa gctcatcaga cacaacaact gcagcattga
     7621 tcacagacac aggtggtgta gacgaccgtt cattcaacca gtcagcttgg gaaggactag
     7681 aaaaatgggg gaaagatcaa ggactttcac gaggaaatga tggcttccaa tatttccaat
     7741 cttcaaatga atcagattac atcccaaata ttgaccaagc attgaatgct ggattcaaaa
     7801 cgatttttgg tattggttat aaactaaaac cagcgatcca agaacaagca acaaacaata
     7861 caggtacgaa ctttgttatt atcgatgatg tcatcgatgg attagataac gttgtatctg
     7921 caactttcaa agacaacgaa gcttcttatc ttgcaggtgt tgcagcagct tatacgactg
     7981 aaacaaacgt agtcggcttt atcggcggtg taaaaggtga agtaatcgat cgttttgatg
     8041 ctggattcaa agccggtgtt gatgcaggtg cgaaagaatt aggaaaagaa atcaaagtat
     8101 tgaatcaata tgctggtgac ttctctgctc cagataaagg acgttcaatt gctcaaggta
     8161 tgtatgcaca aaacgcagat atcatcttcc atgcttcagg cggtacaggt aacggtgtat
     8221 tccaagaagc aaaatcattg aacgaatcag gcgacaaaaa agtttgggtt atcggtgttg
     8281 accgcgacca atcagacgaa ggcgaataca cattaaacgg cgaaaagaaa aacttcacat
     8341 tgacatctac actgaaagca gttggaacag tagtagaaga tttggcacaa aaatcagcgg
     8401 acggtaaatt ccctggcggc gaacacactg tttatggatt gaaagaagac ggtgttggtc
     8461 taacagaagg acaactttct gacgaagcga aaaaagcagt tgatgaagca aaagaaaaaa
     8521 tcatttcagg tgacgtaaaa gttccagaaa ctcctgaaga aaactaaaac catttctata
     8581 gccttgttag acacatgttt gacaaggcta tggtttgatt agaacaagaa ttgttcattt
     8641 atccaagctg ccttgtgaca gtttggataa gggaacaact ccctgaagta atgtttgttt
     8701 caaaagaaga acgctcacta agcgtgaatc ttagtcaatc gttgccctag atagaaatcg
     8761 ttaggatgtg aaaaaaaggt ggttcaagaa aatattgtca tagaaatgca gaatattacc
     8821 aaagaatttg gaacattcaa ggcaaatgac aacatcaatt tacaagtaaa ggcaggagaa
     8881 attcatgcgt tgcttggaga aaacggtgct ggcaaatcta cattgatgaa cgtgctttcc
     8941 ggattattag agccgacatc agggaaaatt ttgatgcgtg ggaaagaagt aaagatcaca
     9001 agtccgacca aagccaacca attagggatt gggatggtcc atcagcactt tatgcttgtt
     9061 gatgccttta ctgtaacaga aaacatcgtg ttgggaagcg agcctagtcg cgcagggatg
     9121 cttgaccata aaaaagcacg aaaagagatc caaaaagttt ctgaacagta tggattgtca
     9181 gtcaacccag atgcttacgt tcgtgatatt tcagttggaa tggaacaacg ggtagaaatt
     9241 ttaaaaacac tttaccgagg agcagatgta ctgatttttg atgagccgac agctgtattg
     9301 acccctcaag aaattgatga attaatcgtg atcatgaagg aattagtcaa agaaggcaag
     9361 tcgatcattt tgattacgca taagttagat gaaatcaaag cagtagctga ccgctgtaca
     9421 gttatccgcc gtggaaaagg aatcggtaca gtcaacgtta aagacgtaac ctcacaacaa
     9481 ttagccgata tgatggttgg aagaacggtt tcattcaaaa cgatgaaaaa agaagcgaag
     9541 cctcaagaag tcgttttgtc tattgaaaat ctagtggtga aagaaaatcg tggattagaa
     9601 gccgtgaaaa acttgaactt agaggttcgt gctggcgaag tacttggtat cgctggaatc
     9661 gatggaaacg ggcagtcgga gttgatccaa gctttgactg gtttgcgaaa ggcagaaagc
     9721 ggacatatca agctaaaagg ggaagacatc actaataaaa aaccccgaaa aatcactgaa
     9781 catggtgtag gacacgtgcc agaagaccgt cataaatacg ggttagtcct agatatgaca
     9841 ttatctgaaa atatcgcact acaaacctat catcaaaaac cttacagtaa aaacggcatg
     9901 ctgaattatt cagtaatgaa tgaacatgcc agagaattga tcgaagaata tgatgttcga
     9961 acaacgaatg aacttgttcc cgcaaaagct ttatcaggcg gaaatcagca aaaagcaatt
    10021 atcgctcgtg aagtcgaccg agatcctgat ctgttgattg ttgcaaatcc aactcgtgga
    10081 ctggatgtag gtgcgatcga atttattcat aaacgtctga tcgaacaaag ggacaaatac
    10141 aaagcagtgt tactgatcag tttcgaatta gaagaaattt taaatgtttc ggatcgtatt
    10201 gctgttatcc atgaaggaga aattgtcggt atcgttgatc cgaaagaaac atctgaaaat
    10261 gaattaggtc tattgatggc gggctatacc ttagaagaag cacgaaaaga gttagaaaag
    10321 ggggctggcg cacatgaatg atcgcagcga aaaattccgt aatttattag tgcctgtact
    10381 ttcagttgtt ttaggattga tcttaggcgc gatattgatg gctgcttttg gttttcagcc
    10441 catccaaggt tattcttcta tgctagatgc agcccttggt tcgcaaagag ggataggtga
    10501 aacgttaagg caagcaacgc cgttgatttt tacagcatta ggtttttctg tagctaactc
    10561 agctgggttt ttcaatattg ggctttctgg acaagcactt tgcgggtgga tcgtcagtgt
    10621 ctgggtggca cttgcgtttc cagatctgcc aaaagttgtt ttgcttccgt tatgcgtgat
    10681 cttaggtgcc ttagctggtg cgatggcagc ggctgttcca ggtttacttc gagcattttt
    10741 tggaacaagt gaagtgatcg taacaatcat gatgaactat atcttattat acgtaagcac
    10801 atttgcttta catgaagtga tgcctgaaag ctatcgctca agtttggact cttccaatat
    10861 gatcagtcaa aatgcctcac tgcggttacc atggttaaca caagcttttg gcggctctcg
    10921 cgtaaactca ggattatttt tagcaatcat cgcgcttatt ttcgtttggc tgctgatgaa
    10981 gaaaacgact ttaggatttg aaatccgttc tgttggattg aatccttttg cttctgagta
    11041 tgcaggaatg agtagtaaac gtacgatcgt tttgtcgatg gtcatttctg gcgctttggc
    11101 agggcttggc ggtgtggttg aaggattagg aacgtatcaa aacttctttg ttcaaacgac
    11161 ttcgctatct attggatttg acggaatggc tgtttccttg cttggttctg gatcagcaat
    11221 cggtattctt ttatcagcga tcttgttcag tattttgaag atcggtggac ttggcatgca
    11281 gacaggagca ggtgttccgt ttgagatcgt caatgtatcg attgctttga ttatcttctt
    11341 tgtcgggatc aacttcctga ttcgtttcgt catggctaaa gtcttccaag ggaaaaaaca
    11401 agaagagatc gttgcgacaa tagaatcgaa accaacgaat caaaaccatg aagggggcga
    11461 actataatgt cgactatcga attaattgcc ttgatcctta cttctacact ggtttattca
    11521 acaccgctaa ttctaacgtc actaggcgga actttttctg aacgaagcgg gatcgtaaac
    11581 gtagggctag agggaatcat ggtcatgggt gcttttagtt ccatcgtttt caacttgacg
    11641 atgagtccat cacttggttc tatgacacca tggatcgcta ttttagtggg tggcgtcgta
    11701 ggtatcctat tttctctgat tcacgcagta gcaacagtca gtttgcgtgc tgaccatatt
    11761 atcagcggga cagtaattaa tctgatggca cctgctttag gtgttttctt gatcaaagca
    11821 tggtatggta aaggtcaaac tgataacatc acgcagaatc tggggtattt ttctttccca
    11881 ggattagcag atattccggt cattggacca attttcttta aaaatacatt cttacctgct
    11941 tattgtgcta ttttgattgc tgtcctagct tgggtgatca tcttcaagac gaaattcggc
    12001 ttgcgcctcc gttcagttgg tgaaaatcct caagctgccg acacattagg tatcaatgta
    12061 tatgctatgc gttattcagg cgtactgatt tctggcttgt taggcggtat gggcggtgct
    12121 gtttttgctc agtcgatttc cggtaacttt tcagctggta cgatcgttgg acaagggttc
    12181 atctccatgg ctgctatgat ctttggtaag tggaatcctt taggggcaat gggtgcctca
    12241 ttgttctttg gttttgctca aagcttgagt atcattggcg cacaattacc agttatttct
    12301 tcgattccgc cagtattgct gcaaattgct ccatatttgc tgacaatcat tgtgctggtt
    12361 gttttcttag ggaaagcttc tggtccaaaa gcaaacggga agaactatat caaatcaaaa
    12421 taatctttta gcgaataaaa agggtgggtt acgggaagtg tttttcgtct cgcccttttt
    12481 gttttaaagg caataaaaat aaaaagaaag aaggaataat catgtttaaa cgcgtacatc
    12541 tgatcgtcat ggattcagta ggaattggag aagcaccaga tgccgataag ttcggtgatg
    12601 ttggttctga tacattagga cacattgcga aagaagcagg attgaacgtt ccacatttag
    12661 agcagcttgg tttaggaacg atccgtcctc ttgaaggtgt ggaatcagtg aaagatcatc
    12721 aaggctatgc gacgaaatta gaagaagttt ctgtagggaa agatacgatg acaggccact
    12781 gggaaatcat gggattgaat atcaaaactc catttcgtgt gtttcctaat ggattccctg
    12841 atgatctgat caaacaaatc gaagaatttt ctggccgtaa agtcgtatgt aacaaacctt
    12901 atagcggaac agctgttatt gacgattacg gtgaacacca aatgaaaaca ggcgatttaa
    12961 ttgtatatac ttctgccgat cctgtccttc agatcgcggc acatgaagaa atcattcctt
    13021 tagaagaatt atatcggatt tgccaattcg ttcgtgatat aacaaaagat gatccgtata
    13081 tgattggccg aatcattgca cgtccgtacg tgggtgaacc aggagacttc acacgaacaa
    13141 gcaatcgcca tgattatgcg ttgaatccat tcggacacac agtccttgat tctttgaaag
    13201 aagcaggaaa ggacgtgatt gctgttggaa agatcaacga tattttcaac ggacaaggaa
    13261 tcactgaatc tgtccgcacg aaaagcaata tggatggcgt tgaccagctg ctgaaagtta
    13321 tgaaaaacga tttttcagga atcagcttta ccaatttagt agattttgat gcattatacg
    13381 gtcatcgtcg ggatgtagtc ggctatgcgc atgcgattga agaatttgac ttacgaattc
    13441 cagaattgct tgaagcgatg gaagaagacg acttgctaat gattacagcc gatcacggaa
    13501 acgatccgac gtttactggt accgatcata cgcgagaata tgtaccgtta ttggtttaca
    13561 gtaaaaaaat gaaagaacaa ggggcattgc ctcaaggata ttattcagat atttcagcaa
    13621 cgattgctga gaactttagt gtttcttcga ctgaaaatgg cgaaagcttc ttgaaattat
    13681 taaaataatc tttttaaata ggagaaagca aatgaccaag ttaagcgaga tgttacaaga
    13741 aacgacccag tttatccttg ataaaggagt aaaagaaatt gattttggtt tgattctagg
    13801 ttcaggatta ggtgaattag cagatgaaat cgaagatgct gtaatgattt cttatgatga
    13861 gatcccgttc tttcctgttt cgacagtagt tgggcatgca ggaaagctag tttatgggtc
    13921 tctggcaggc aagaaagtgt tagccatgca agggagattc cactactatg aaggtcattc
    13981 catgcaaaca gtgacctatc cagtacgtgt gatggccgga ctaggggccc attcagtcat
    14041 tgtgactaat gcatgtggtg gtgtcaacga atcatttgta ccaggagatt tgatgctgat
    14101 taccgatcat atcaatttta ctggtgaaaa tcctttgatc ggtccaaatg aagatgcaat
    14161 gggccctaga tttccagata tgagtcaagc ttatacgcct gactatcaag caacagcaaa
    14221 agcagcagca gaaaaactag gtttggatct taaagaaggc gtatatatgg gctattctgg
    14281 accaacttat gaaacgcctg cggagatccg aatgtctcgg acaataggag ccgatgcagt
    14341 agggatgtcg actgttccag aagtcatcgt agcagctcac agcggattaa aagtgttagg
    14401 aatctcttgt attaccaact tagcagcagg tatgcaagcg aatctgagcc atgaagaagt
    14461 tgtagaaaca actcagagag tcaaacaatc ttttaaagca ttggttaaag aaacattgac
    14521 attattgtaa taggaggaac aataaaatga gtgtgcatat tgaagcgaaa gaaggcgaga
    14581 tcgccgataa gattttactt ccgggagatc ctttgcgagc taaatatatt gcggagactt
    14641 ttttggaaga tccagtttgt tacaatcagg tacgcggtat gttaggcttt accggcaaat
    14701 ataaaggaga acgtatttct gttcaaggaa caggaatggg aatgccatca gccaccatct
    14761 atgcccatga attgatccag tcgtatggtg taaagaaatt gattcgagta ggtacatgcg
    14821 gtgcattgtc aaaagacgtc catgttcgtg atttagtact agcacaaggt gcagcgacca
    14881 gttcttcgat gatcgaaaaa aatttccaag cctttcattt tcctccaatc agtgatttca
    14941 atctattact gaaagcatat gagatagcta aagaaaaggg ctatacggtt catgtaggaa
    15001 atgttctttc ggaagattct ttctacaaag atgatttgac agagacgttc caattagctg
    15061 aacttggcgt tttaggagtg gaaatggaag cagcggctct ttattactta ggcgcgaaat
    15121 accatgtgca gacattaagt ttgatgaccg ttagcgacca tttgatcacc ggtgaagaaa
    15181 caacagctgc agaacgtcaa tctacgttca atgaaatgat cgaagtagga ttggaaacag
    15241 cgatagcaga ataagaagga aatgaaaaag ctgccctgca ttaagtaata agaacatcca
    15301 agcaaaaata gctcctcatg tttttgactt ggctggactt attattgcaa atgtaagctt
    15361 ttgaacaccg tttaccaaga ggttgtgaat ctgccgttta actctgagtc acaaggaaca
    15421 atttcaaaaa acagcttttc atgtttgatg aatattgtga cttgtgaccg agaagttggc
    15481 aggagaaaac cgtttatacg aaaaaaggga ctgtgacaaa tcgtgtcaca gtcccttttt
    15541 tatagtgttt tttataggta gtatttttta gcaactgtta agtcatcatt taattcataa
    15601 acaagtggtt gacctgttgg aatttcaaga tccatgatgt cttcgtcaga gataccttcg
    15661 atatgtttag ctagggcgcg taatgagtta ccatgtgcag ctactaaaac agttttgttg
    15721 tctagtaatg ctggagcaat ttcatcttgc cagaatggca aagcgcgttc taatgtcact
    15781 ttcaagtttt ctccaccagg aatatcgcgt ttgtctaaca ttgcgtaacg acggtcattt
    15841 gctgcagaac cttcgtcagt ttcttccatt aatggaggaa gagtatcgta agaacgacgc
    15901 cagatgtgca cttgttcgtc gccgtatttt tcagctgttt cttttttgtt caaaccttgt
    15961 aatttaccat agtgacgttc gtttaagcgc catgatttga tttgtggtac ccaaagttga
    16021 tctgaatatt ctaagatcaa gttacatgtt ttgattgcac gagttaaaac agaagtgtaa
    16081 gcaacatcaa attcgattcc agcttctttg attttgcgtc cgccttcttt tgcttcttcg
    16141 attccttctg gtgctagatt tacatcagcc caaccagtaa attggttcaa tgcattccat
    16201 tcactaagac cgtgacgaga aaaaactaat tttggcatgt ttagctctcc ttttaagata
    16261 ggtttatatt tctgaaattt tcagttctgt tttattgtac aattttttgg aagagatttc
    16321 catcgaaaaa ttagataaga ttctatgaga aaacaagtag agaatataaa aaaacgaaca
    16381 gtgcccacgc aactgttcgt ttttaggtat tagatgcata attgctcgat ttctttttca
    16441 ggtaaattga tatatttata acatgttcca actgaaacac cgcattttga agaaataaat
    16501 tggatcgttt cttttttttc ataatagaga cgtcggattt ttttgatcgt ttttgcatcg
    16561 atttttggtc ttccgccgat ttttcctttt ttacgagctt catctaatcc aactaatgta
    16621 cgttctttga tcaatgcgca ctccatgttt gctaggtttt ccattaattg gaaatagatt
    16681 tttcccattt cgcgcgtatc gattccttca tcaagactaa tcaagtgcag cccgcgatct
    16741 ttgaataatt gcgtgagttc tgttaattgc cgcgtagatt tgcctaatcg atgaagttgg
    16801 caaatgacta gtgcatcgcc ttgttgcatg tcagcgatca ctgactccaa atgaacagca
    16861 gtagaatcat tttgttccac ttcatatgtc tcatggaaaa tttcttgaca accaaagtca
    16921 gataattgat caacctgagt tgttaaatca acgtcattta tggttgtgcg tgcataacca
    16981 ataattttca tggtgattcc tttctagcag tgattttcta actggatata acagtaaaaa
    17041 tgtagcataa agtacgtcaa aaagatagtt ttttcgcaaa ttttccgctg tcttttttta
    17101 ttggatgatc aagcagtttt tctttattta cgacggattg cgtcaagaat ctcaacgcct
    17161 ttttctgagc cgacaactac tttagaaacc atgtttagga aaagcccatg ttctactacc
    17221 ccaacaagtt catctaaata ggtagctaag ctttctggct gttcgatgac ttctagatgc
    17281 agatcaatga tgtaatgacc accatctgtg gttaagactt ctccgttttc gtctgtacgc
    17341 aagacgggtt ggaatctttt ttcttcaaaa atatgaagta gctgttggga gccataaggg
    17401 atcacttcaa ctgggagtgg gaacttccca agtttatcga ctaatttaga agaatcaacg
    17461 atccaaatcg tttcttttga gtacgtagcg actattttct cgaaaagcaa agcagcgccg
    17521 ccgcctttga tcccttgaaa atcagcactg atttcatcag caccgtctat tgtcaaatcg
    17581 actacgggga cttcatcaat actctttaac ggtattccta atttttccgc ttgttctttt
    17641 gtcgcatttg aagtagtaac tcctgtgata cgtaaacctt cttcacgcat acggcgacca
    17701 atctcttcta ccatataata ggcggttgaa ccggtcccga gacctacgat catcccgtcc
    17761 tttacgaatt tcgcggcttc aatgccagct aattgtttta aattcatctt tgcgtccacc
    17821 tttttttagt ttgagcatcg tgctttcctc actattttag cgtgatttac ggtaaaaaga
    17881 taccattctt ttttattcca ataaagcttt ttcaaaaaaa attgcatctc ttgttgacat
    17941 gttttttcat tcgtgatatt ctaacaaagg tgctttatct acaggtttct gtgaagaaac
    18001 gtgctgactg tttatcaaag catatttgat aaggatgcag acattgcatt tattttttat
    18061 cacaaaaaaa gaaccacctg gatgtgtgga actagacgca aatcgtggga aggaggaaac
    18121 aaggaatgcc tacaattaac caattagtac gtaaacctcg taaatcaaag gtggaaaaat
    18181 ctaattcacc tgctttgaac aaaggatata acagctttaa gaaaactcaa actaacgtaa
    18241 actcacctca aaaacgtggg gtagcaactc gtgtgggtac aatgacacct aaaaaaccga
    18301 actcagcttt acgtaaatat gcacgtgttc gtttgtcaaa cttaattgaa gttactgctt
    18361 atatcccagg gattggtcat aacttacaag aacacagtgt tgtattatta cgcggtggtc
    18421 gtgtaaaaga cttaccaggg gtacgttacc atatcgttcg cggtgcttta gatactgctg
    18481 gtgttaacga ccgtaaacaa agccgttcta aatacggaac taaaaaacct aaagcttaat
    18541 tttaattatt aaacaaatga aacttgcttc tactatatag aagtaattac tatgaacaat
    18601 atttcggaag gaggagttac ggatgccacg taaaggtcct gttgcaaaac gtgatgtttt
    18661 accagatcct atttataact caaaattagt aactcgcttg atcaaccgtg taatggttga
    18721 cggaaaacgc gggattgcag ctaacattat ctataatgcc tttgacttga tcaaagaatc
    18781 tacaggtaac gatccattag aagtgtttga acaagcaatg aaaaacgttc aacctgttct
    18841 tgaagttaaa gcacgtcgtg ttgggggttc aaactaccaa gtaccagttg aagttcgccc
    18901 tgaacgccgc gttactctag gtcttcgttg ggtagtaaac tacgctcgct tgcgcggtga
    18961 acacacaatg gaagaacgct tagcaaaaga aatcatggat gctgcaaaca acacaggtgc
    19021 ttctgttaaa aaacgtgaag acactcataa aatggctgat gccaaccgtg cgtttgctca
    19081 ctatcgctgg taagattctc tctgtttggt cggcttttat aagtcgacct cagatagtgt
    19141 ccttattttt agcaactaga tagtaaagag aggagaaaca aggagaatga ccagagaatt
    19201 ttctttacaa aacactcgta atatcggtat catggcccac atcgatgctg gtaaaacgac
    19261 tgctactgaa cgtatcttgt actatactgg taaaatccat aaaattggtg aaactcatga
    19321 aggagcttca caaatggact ggatggaaca agaacaagaa cgtggtatta cgatcacttc
    19381 tgctgctact acagcacaat ggaagggtca ccgaatcaac atcatcgaca caccaggaca
    19441 cgtagacttc acagttgaag ttgaacgttc attgcgtgta cttgatggtg ctgtaactgt
    19501 tcttgatgca caatcaggtg ttgaacctca aactgaaaca gtttggcgtc aagcaacaac
    19561 ttatggtgta cctcgtatcg tatttgcaaa caaaatggac aagatcggtg ctgacttctt
    19621 atattcagta tcaactttac atgaccgttt gcaagcaaac gctcacccaa tccaattacc
    19681 aattggtgcg gaagacgact tcacaggaat tatcgacctt gtaacaatga aggctgaaat
    19741 gtatacaaac gatcttggaa cagagatcga agaaacagaa attcctgaag aataccgcga
    19801 attagctgaa gaatggcgcg aaaaattggt tgaagctgta gctgaaactg atgaagaact
    19861 tactttgaaa tacttagaag gtgaagaaat cactgaagct gagttaaaag aaggtatccg
    19921 ccgcgcaaca gttaacgtag aattctaccc agtactatgt ggttcagcat ttaagaacaa
    19981 aggggttcaa ttactattgg acgctgttct tgattacttg ccatcaccgt tagatatccc
    20041 agctatcaaa gggattgacc ctaaaactga tgaagaagta gaacgtcctg cagacgacag
    20101 cgctcctttc tcagctttag catttaaagt tatgactgac ccattcgtag gtcgtttaac
    20161 tttcttccgt gtgtactctg gtgttttaca atcaggttca tacgtacaaa acgcaacaaa
    20221 aggcaaacgt gaacgtgttg gtcgtatcct acagatgcat gccaactctc gttcagaaat
    20281 ctctgaagtt tacgctggag atatcgctgc tgctgttggt ttgaaagaca caactactgg
    20341 ggacacacta tgtgatgaaa agagtctagt tattcttgaa tccatggaat tcccagaacc
    20401 agttatccaa gtcgctattg aacctaaatc aaaagctgac caagataaaa tgggtgtggc
    20461 tttacaaaaa ctatctgaag aagatcctac tttccgtgct gaaacaaacg tggaaacagg
    20521 cgaaacaatc atcgctggta tgggtgaact tcacttagat atcatcgttg accgtatgcg
    20581 tcgtgaattc aaagttgaag ctaacgtagg tgcgcctcaa gtatcttacc gtgaaacttt
    20641 ccgtgctggc actcaagccg aaggtaagtt tgtacgtcag tctggtggta aaggtcaata
    20701 cggtcacgta tggattgaat ttacaccaaa tgaagaaggt gctggtttcg aatttgaaaa
    20761 tgcgatcgtc ggtggggttg ttcctcgtga atacattcca gctgttgaaa ctggtttgaa
    20821 agatgctatg gaaaatggtg tcttagctgg ctatccatta gtagatatca aagctaaact
    20881 ttacgatggt tcataccatg atgtcgattc aaatgaaact gccttccgtg ttgctgcttc
    20941 tatggcatta cgtgcagcag ctaagaaagc taatccagta atccttgaac caatcatggc
    21001 tgtagaagtt gttatccctg aagattattt aggtgatgtt atgggtcacg taactgctcg
    21061 tcgtggacgt gttgaaggta tggaagctcg cgctggcggc caacaagttg ttcgtgcgat
    21121 ggttccactt gctgaaatgt ttggttatgc tacaactctt cgttctgcta ctcaaggtcg
    21181 tggtacattt acaatgacat ttgaccacta cgaagatgta ccaaaatcag tacaagaaga
    21241 aatcattaag aaaaacggcg gaaaagctga ataatttctt gaaaccggat agtcctgcaa
    21301 agagattatc caaagagact atatttttaa tatagtttcg tgtaaaataa ttatcgatga
    21361 tatgggcatg tggtgtacct tgtgtacatc atatacctat cagacaaata aaaaatatat
    21421 tgtattttta ggaggacatt ttaaaatggc aaaagaaaaa tttgaccgtt ctaaaccaca
    21481 cgttaacatt ggtactatcg gacacgttga ccatggtaaa actacattaa cagctgcaat
    21541 cacaactgta ctatctaaga aaaacggcgg ccaagctatg gcttacgatc aaatcgatgg
    21601 tgctccagaa gaacgcgaac gcggaatcac aatctcaaca gctcacgttg agtatgaaac
    21661 agatacacgc cactacgctc acgttgactg cccaggacac gcggattacg ttaaaaacat
    21721 gatcactggt gctgctcaaa tggacggagc tatcttggta gtttctgctg ctgacggccc
    21781 aatgcctcaa actcgtgaac acatcctatt gtctcgtcaa gttggtgttc cttacatcgt
    21841 tgtattcttg aacaaagtag acatggttga tgacgaagaa ttactagaat tagttgaaat
    21901 ggaagttcgt gacctattaa cagaatacga attccctggt gacgatgttc ctgtagttgc
    21961 tggatcagct ttgaaagctc tagaaggcga cgcttcatac gaagaaaaaa ttcttgaatt
    22021 aatggctgca gttgacgaat acatcccaac tccagaacgt gacaacgaca aaccattcat
    22081 gatgccagtt gaagacgtgt tctcaattac tggacgtggt actgttgcta caggtcgtgt
    22141 tgaacgtgga caagttcgcg ttggtgacga agttgaagtt gttggtattg ctgaagaaac
    22201 ttcaaaaaca acagttactg gtgttgaaat gttccgtaaa ttgttagact acgctgaagc
    22261 tggagacaac attggtgctt tactacgtgg tgttgcacgt gaagacatcc aacgtggaca
    22321 agttttagct aaaccaggta caatcacacc tcatacaaaa ttctctgcag aagtatacgt
    22381 gttgacaaaa gaagaaggtg gacgtcatac tccattcttc actaactacc gtccacaatt
    22441 ctacttccgt acaactgacg taacaggtgt tgttgaatta ccagaaggaa ctgaaatggt
    22501 tatgcctggc gacaacgtaa caatggaagt tgaattaatc cacccaatcg ctatcgaaaa
    22561 cggtactaaa ttctcaatcc gtgaaggcgg acgtacagtt ggtgccggtg tcgttacaga
    22621 aatcaaagct taattcactt aagttttaaa gtaaagcaac atttattcgg acgtaatcgc
    22681 tcggaacgaa ggtcttagga tctttgttcc gagctttttt atttattgca ggatcaggaa
    22741 aaaagacagg agtattataa atagaagaaa cacgaaataa aagagtcagt attttctaaa
    22801 tgaaacttta tgaaaacaaa atgtttttta caagaaaaag ccttgctttg tgagtttata
    22861 tatattataa tgacaaaggt gcgtttactt tagtgaattg cacagacgta atcagaatga
    22921 tttcgtcggc taagaaacga gaggttgcga cacgcccgga cgctttgcca cgaacgagcg
    22981 tgacggaaat tttcgtggag ctatgtctac ttttcaaaat aggcgaagga gggaacaaga
    23041 tggcaaaaca aaaaattcgt atccgtttaa aagcgtatga acaccgtatt ttagatcaat
    23101 cagcggataa aatcgtggaa actgcaaaaa gaactggagc tagcgtgtct ggtccaattc
    23161 cattaccaac tgaacgcagt ctttacacaa tcatccgtgc gactcataaa tacaaagatt
    23221 cacgcgaaca attcgaaatg cgtacacaca aacgtcttat cgacattgtg aacccaacac
    23281 caaaaactgt tgatgctttg atgaagctag acttaccatc tggtgtaaac atcgaaatca
    23341 aattataaaa ctaaaacaaa aataatggag gtgtactcat gaccaaagga atcttaggga
    23401 aaaaagtggg aatgacacaa atcttcactg aatctggtga attaattcca gtaactgttg
    23461 tagaagctac tccaaacgta gtactacaag tgaaaacaat ggaaacggat ggctacgaag
    23521 ctattcaagt tggttaccaa gatatgcgtg aagttttatc aaacaaacct gcgaaaggtc
    23581 atgttgcaaa agcaaacacg gctcctaagc gcttcattcg tgaattcaaa aatgttgagc
    23641 taggagaata tgaagtagga aaagaaatta cagtagatgt tttccaagca ggagacatta
    23701 ttgatgtaac aggtactacg aaaggtaaag gattccaagg ggttatcaaa cgccacggac
    23761 aaagccgcgg accaatggct cacggttctc gttaccatcg tcgtcctggg tcaatgggtc
    23821 cagttgcacc taaccgtgta tttaaaaaca aacgtcttgc tggccgtatg ggtggcaacc
    23881 gcgtaactat ccaaaacttg gaagttgtac gtgtcgatgc agaaagaaat gttatcttga
    23941 tcaaaggtaa tgttcctgga gctaaaaaat ctttaattac tatcaaatca gctgtgaaag
    24001 ctaaataatt gtaggaagaa aggaggaact aaggaatgcc gaatgtagca ttattcaaac
    24061 aagatggaag ccaaaacggt gaaatcacac ttaacgaaga aatcttcgga attgaaccta
    24121 atgaaagtgt tgtttacgat gcaatcgtaa tgcaacgtgc gtcattaaga caaggaacac
    24181 acgcggttaa aaaccgtagc gctgttcgcg gcggcggacg taaaccatgg cgtcaaaaag
    24241 gaacaggtcg tgcacgtcaa ggatctatcc gctcaccaca atggcgtgga ggtggcgtag
    24301 tctttggacc aacaccacgt tcttacagct acaaacttcc taaaaaagtt cgtcgtttag
    24361 caatgaaatc tgtattgtca gaaaaagttg ctgaaaacaa cttggtagca atcgaaggct
    24421 tgaacttcga cgcaccaaaa acaaaagaat tcaaacaagt tcttgctaac ttatctatcg
    24481 actctaaagt attggttgtt ctagaaaaag gtaacgactt tgctgcttta tcagcacgta
    24541 acttaccaaa cgtttctgta gtaacttctg ataatgtgag tgtgctagac gttgtatcaa
    24601 atacaaaagt gttagcaaca caaactgctc ttactcaaat tgaggaggtg cttgcataat
    24661 gaacttacta gacgtaatca aacgcccagt gatcactgaa aaatcaatgc ttgccatgga
    24721 tgacaagaaa tacacttttg aagtggacac tcgcgcaaac aaaactttag taaaacaagc
    24781 ggtagaagct gcttttgacg ttaaagtcaa aaacgtgaac atcgtgaacg tacgtgcgaa
    24841 attcaaacgt atgggcaaat atgcaggata tacaaaaaaa cgtcgcaaag cgatcgttac
    24901 attgactgaa gattcaaaag aaatccaatt attcgaagct gctgaataag cactaataga
    24961 taactcatta aattaggagg gaaaaacgtg gcgattaaaa agtacaaacc tacctcaaat
    25021 ggtcgtcgta acatgacagg ttctgatttt gctgaaatca caacatcaac acctgaaaaa
    25081 tcattgttac aaccattgaa aaaccatgct ggacgtaaca acaacggccg catcactgta
    25141 cgtcatcaag gtggcggaca caaacgccaa tatcgcgtga tcgacttcaa acgtaacaaa
    25201 gataacgttg ttgcaactgt tcaaacgatc gaatatgatc caaaccgttc agctaacatc
    25261 gcgttagtac actatgaaga tggagtgaaa gcttacatct tagcacctaa aggactagaa
    25321 gtgggtatga aacttgtttc aggtccagaa gcagatatca aagtcggaaa tgctcttcca
    25381 ttagaaaaca ttccagttgg tactgttatc cacaacattg aaatgaaacc tggtaaaggt
    25441 ggacaattga tccgttctgc tggtacaagt gctcaagtac ttggtaaaga aggcaaatac
    25501 gtattgatcc gcttgaactc tggtgaagtt cgtatgatct tagctgcatg ccgtgctaca
    25561 atcggttctg taggtaacga acaacacgaa ttaatcaaca tcggtaaagc tggacgctct
    25621 cgttggatgc gtaaacgccc aactgtacgt ggtagcgtaa tgaaccctaa tgatcaccca
    25681 cacggtggtg gtgaaggtaa agctcctatc ggacgtaaag caccagtttc tccttggggt
    25741 caaccagctc ttggttacaa aactcgtaac aaaaaagcta aatcagacaa acttattgtt
    25801 cgtcgtcgca aaaataaata attactttga ccatgtgtcg cacattttga gaggaggttc
    25861 accatgggtc gtagtttaaa gaaaggacct tttgtcgatg agcatttaat gaaaaaagtt
    25921 gaagctcaag caggggttga aaagaaaaaa gttatcaaaa cttggtcacg ccgttcaaca
    25981 gttttcccaa gttttgttgg atataccatc gcagtttatg atggacgtaa acatgtacca
    26041 gtttacatcc aagaagacat ggtaggacac aaattaggtg aatttgcacc tacaagaact
    26101 tatcgtggac atgctgctga cgataagaaa acgaaacgct aatttgaggg gaggataaat
    26161 ccaaatggca gaacaaatca catcagctaa agcaactgca aaaacagttc gcacttcacc
    26221 tcgaaaagcc cgtttagtaa ttgaccttat cagaggtaaa agtgtcgcag atgcaatttc
    26281 aatcttgaaa ttcacaccaa acaaatctgc tggaatcatt gaaaaagtat tgatgtcagc
    26341 agttgcgaat gcagaaaata actttgactt agatgttgaa aacttggtag taagcgaagc
    26401 ttttgttaac gaaggaccta caatgaaacg tttccgtcct cgtgcaaaag gatcagcttc
    26461 tccaatcaac aaacgtacaa gtcatatcac ggtagtcgta tcagaaaaat aaggagggat
    26521 aatcagtggg tcaaaaagta catccaattg gaatgcgtgt aggcatcatc cgcgactggg
    26581 atgctaaatg gtatgctgaa aaagagtatg ctgagttctt acacgaagat ttaagaatcc
    26641 gtaaatttat ttcaactaaa cttgctgatg ctgctgtatc aacagttgaa atcgaacgcg
    26701 caacaggtcg cgtaaacatt tcaattcaca cagctaaacc aggtatggtt attggtaaag
    26761 gcggttctga agtcgaaagc ctaagaaaag aattaaacaa attaactggt aaaagaatcc
    26821 atatcaatat cgtggaaatc aaaaaaccag atctagatgc aaaattagta ggtgaaggaa
    26881 tcgcacgtca attagaaaac cgtgttgctt tccgtcgcgc tcaaaaacaa gccatccaac
    26941 gctcaatgcg tgctggcgct caagggatca aaactcaagt atctggtcgt ctaaacggag
    27001 cagatatcgc tcgttcagaa ggatactcag aaggaactgt tcctcttcat actttacgtg
    27061 cggacattga ttacgcatgg gaagaagcag atacaacata cggaaaacta ggagttaaag
    27121 tgtggatcta tcgtggagaa attcttccaa ctaaaaaaaa cactgagaaa ggagggaaat
    27181 aatcatgtta gtacctaaac gtgtaaaaca ccgtcgtgaa ttccgcggaa aaatgcgcgg
    27241 ggaagctaaa ggcggaaaag aagtagcatt cggtgaatac ggtttgcaag ctgttgattc
    27301 acattggatc acaaaccgcc aaatcgaagc tgctcgtatc gcaatgactc gttacatgaa
    27361 acgtggtggg aaagtatgga ttaaaatttt ccctcacaaa tcttatactg ccaaagcaat
    27421 tggggtacgt atgggttctg gtaaaggggc acctgaagga tgggttgcac cagtaaaacg
    27481 tggtaaaatc atgtttgaaa tcgcaggcgt tcctgaagaa gtagctcgtg aagcgttacg
    27541 tctagcttct cacaaattac caatgaaaac taagatcgta aaacgtgagg aaatgggtgg
    27601 tgaatcgaat gaaggttaaa gaaatcagag aattaaccac tgccgaaatg cttgatcaag
    27661 aaaaacaatt aaaagaagaa ttgtttaatc ttagattcca attagcaaca ggtcaattag
    27721 aaaacactgc acgtattaaa gaagtacgta aatcgattgc acgcatcaaa actgtgttgc
    27781 gtgaacaagc taagtaatta tggaaggagg ccattaagcg tatgactgaa ggaagaaatc
    27841 aacgcaaagt ttatcaaggt cgcgtggttt cagacaaaat ggataaaaca attaccgttg
    27901 ctgtcgaaac aaagaaaaac caccctatct atggcaaacg catgaactat tctaagaaat
    27961 acaaagtgca tgatgaaaac aacacagcaa aagttggcga catcgtgaga attatggaaa
    28021 ctcgtccatt atcagctaca aaacgtttcc gtttgttgga agtagtcgaa gaagcagtta
    28081 ttatctaata acacgagatt ttcctatata gattgaatgc aaaatctgaa aggaggatac
    28141 acaacgtgat ccaagcagaa agtcgtttaa aagtcgctga taactcaggc gcacgtgaaa
    28201 ttttgacgat caaagtcctt ggtggatctg gtcgtaaaac tgctaacatc ggtgatgtga
    28261 tcgttgctac ggttaaacaa gcaacgccag gtggggttgt caaaaaaggt gacgtcgtta
    28321 aagccgttat cgttcgaaca aaatcaggag ctcgtcgtac agacggttca tatattaaat
    28381 ttgatgaaaa tgctgcagtg attattcgtg atgataaaag ccctcgtgga acacgtatct
    28441 ttgggccagt tgcacgtgaa ctacgtgaaa acaacttcat gaagatcgtt tcactagcac
    28501 cagaagtttt ataatcttga gacacttatc aaaggaggtg cgaaacagtt atgtttgtta
    28561 aaaaaggcga taaagttaaa gttatcactg gaaaagacaa aaacaaagaa ggcgttgtac
    28621 tagcagcgtt cccgaaaaaa gataaagtta ttgtcgaagg tgtaaatgtc gttaaaaaac
    28681 accaaaaacc ttctcaagct gctcctcaag gtggaattgt tgagatggaa gcgccaattc
    28741 atgtttctaa cgtgatggtg gttgactcta ctggtgtagc tggccgagtt ggctacaaag
    28801 aagtagacgg caaaaaagtc cgtgtttcta aaaaaaccgg tgaagtttta gataaataaa
    28861 agtttaagga aggagggtct tactgaatga accgcctaaa agaaaaatat cttaaagaag
    28921 taactccatc attgatggaa aaatttaact atagctctgt tatgcaaaca cctaaagttg
    28981 aaaaaatcgt catcaacatg ggtgttggtg atgcggtatc aaacgctaaa aacttagata
    29041 aagcagttga agaattaact ttgatcactg gtcaaaaacc aatgattaca aaagctaaaa
    29101 aatcaatcgc tggattccgt ttacgtgaag gaatgccaat tggtgcaaaa gttacattgc
    29161 gcggagaaag aatgtacgaa ttcttagaca aattggtttc tgtttcacta ccacgtgtac
    29221 gtgacttcca tggtgtaagt aaaaaagcct ttgacggtcg tggaaactat actttaggta
    29281 ttaaagaaca attgatcttc ccagaagtag attatgattt agtagataaa gtacgtggta
    29341 tggacatcgt tattgtaaca acagcaaact ctgatgaaga atctcgtgag ttgttgacac
    29401 aattaggcat gccattccaa aaataattaa aggaggcgaa ctacgtggct aaaaaatcaa
    29461 tgattgctaa aaacaaacgt cctgcaaaat tttcaacaca agcttatact cgttgcgaac
    29521 gttgcggacg tccacattca gtttatcgta agttccatct ttgccgtatt tgcttccgcg
    29581 aacttgccta taaaggtcaa attcccggcg tgaagaaagc tagctggtaa aaagtaaatt
    29641 cgcataagaa ggaggtaaaa gatcaatggt catgacagat ccaattgcag attttctaac
    29701 tcgtatccgt aacgcaaaca tggttaaaca tgagtcttta gaagtacctg catcaaaaat
    29761 taaacgtgac atcgctgaaa tcttgaaacg tgaaggtttc gttcgtgatg ttgaatacat
    29821 cgaagatgac aaacaaggcg tgatccgtgt tttcctaaaa tttggtaaaa acggcgaacg
    29881 tgttatcaca aacttaaaac gtatctctaa accaggtttg cgtgcttatg tcaaagctga
    29941 cgaagtacca aaagtattga acggtttagg tatcgcaatc atttcgactt ctgaaggtgt
    30001 tgtcactgat aaagaagctc gtgaaaaaaa tatcggcggc gaagttatcg cttacgtatg
    30061 gtaatcaagt agaatctaca aggaggtgtc tttaagtgag ccgtatcgga aataaagtcg
    30121 ttgttatccc tgaaggagta acagttactc aagacggaaa caacgttaca gttaaaggac
    30181 caaaaggtga attgactcgt actttttcag cagatatcaa aatgaatatc gaaggaaacg
    30241 aagtaacttt cactcgtcca aacgacagta aagaaatgaa aacaattcat ggaacaactc
    30301 gtgcgaactt caacaacatg gttgtaggtg tcagcgaagg tttccaaaaa gcgttagaac
    30361 taatcggggt tgggtaccgt gcacaattac aaggatcaaa acttgtattg aacgttggtt
    30421 actcacatcc agtagaaatc acaccaccag ctggagtaac tgttgaagta ccagctaaca
    30481 cacaagtaat tgttaaaggt gcgaacaaag aagaagttgg cgaattagct gcaaacattc
    30541 gtggaactcg tcctccagaa ccttataaag gtaaaggtat tcgttatgtt ggcgaatatg
    30601 tacgccgtaa agaaggtaaa actggtaaat aatcgtttag aaaaattgca tagaagccag
    30661 cagcaggaaa aaggcatttg gctgaagttt accttcaaaa aaatacattt ttacttgtgc
    30721 cgcagcttct atttttcgaa acgtatttac tgcttgaaat agtagtacaa taaaaataaa
    30781 gaggtgacaa ttgtgattac aaaaccagat aagaacaaaa cacgtcaaaa gagacatcgt
    30841 cgtgtacgta acaatatctc tggtactgct gagcgcccac gcttgaacgt ttttcgttct
    30901 aacaaaaaca tctacgctca aattattgat gacgtagcgg gtgtaacgct agcaagtgcc
    30961 tctaccttgg ataaagaaat ttcaggtgga acaaaaacag aagcagcaca agctgtcggt
    31021 aaactagttg ctgaacgtgc agctgaaaaa ggcattaaag tagtagtctt tgaccgtggt
    31081 ggataccttt accatggccg tgtgcaagct ttagctgaag ctgctcgcga aaatggacta
    31141 gaattttaga agaaggagga ataccattca tggtttatat cgatccaaaa catttggaat
    31201 tagaagaccg cgttgttgca attaaccgtg taacaaaagt tgttaaaggt ggacgtcgtc
    31261 tacgttttgc tgctttagtt gttgtcggtg acaaaaacgg acacgtagga tttggtacag
    31321 gtaaagctca agaagttcct gaagcaatcc gtaaagcaat tgaagatgcg aagaaaaact
    31381 tagttgaagt acctatggtt ggttcaacaa tcccacacga agtaatcggt gcttttagtg
    31441 gtggtagaat cctaatgaaa cctgctgtag aaggttctgg ggttgctgct ggtggaccag
    31501 ttcgtgccgt attagaatta gctggggtag cagatatcac ttctaaatct ttaggctcaa
    31561 atacaccaat caacgttgtt cgcgcaacag ttgaaggttt gaaacaattg aaacgtgcag
    31621 aagaagttgc agaacttcgc ggcaaatcag ttgaagaatt aatcggataa ggaggacaac
    31681 aataatggct gaattaaaag ttactttaaa acgcagtatt atcggacgtc ctcaaaacca
    31741 acgcgataca gttaaagcgt taggtcttac aaagattaac agttcagtgg ttaagccttc
    31801 taatgaagca attaaaggca tgatcaatac tgtttctcac ctagtggacg ttgaagaaat
    31861 ttaatttaga aaaatcataa ctagaacatt aaggaggtgc caaacctatg aaacttcatg
    31921 aattaaaacc tgctgaaggt tcacgccaag tacgtaaccg tgttggtcgt ggtacttcat
    31981 ctggtaacgg aaaaactgcc ggacgcggac aaaaaggaca aaaagctcgt tcaggcggcg
    32041 gtgtgcgttt aggatttgaa gggggacaaa caccattgtt ccgtcgttta ccaaaacgag
    32101 gattcacaaa cgtgaaccgt aaagactatg cagtcattaa tcttgatgta ttgaaccgct
    32161 ttgaagacgg agctgaagta actcctgttg ctttagttga agctggaatc gtgaaaaacg
    32221 aaaaagctgg aatcaaagta ttagctaatg gggaactaaa caagaaatta actgtgaaag
    32281 cagcaaaatt ctctaaagca gctcaagaag caattgaagc ggctggtgga tcaatcgagg
    32341 tgatctaatg tttagactat taaaagatgc ttttaaagta aaagacatta gatcgaaaat
    32401 cctatttact gtatttgtgt tgtttgtatt tcgcctaggt gcacatatta ctgtaccagg
    32461 cgtaaatgct gcttcattgc aaaacctttc ttctttgcca tttttcaaca tgttgaactt
    32521 ggtaagtggt agtgcgatgc aaaacttttc cattttctca atgggggttt caccatacat
    32581 tactgcttct atcgtcattc agcttcttca aatggacatc gtgcctcgat ttgttgaatg
    32641 gtcgaaacaa ggggaagttg gtcgtaaaaa actgaatcaa gcgactcgat atctgacatt
    32701 agtattggca tttatccaat ctgtcggtat cactgctgga ttcaatcaat acgctcaatt
    32761 aggtttcgtg aataatccta acgtagcaac ttacgtaacg atcggtttga ttctaacagc
    32821 cggtacgatg tttgttactt ggctaggaga acagatcaca gaaaaaggta tcggaaatgg
    32881 cgtatcaatg atcatttttg caggtatcat ttctagattg cctgaaagta tcagagaaat
    32941 ttatgaagat tactttataa atattgatcc ttcagacata tggaaatctg ctatttttgt
    33001 ggccatttta ctagtagcgg tcttgttgat cgtgacattc gtaacatttt tccaacaagc
    33061 tgaacgcaag atcccgatcc aatatacgaa acgcgtagct ggcgcgccta caagcagcta
    33121 tctgccgttg aaagtaaatg cagctggagt tattccagtt atctttgcta gttcgtttat
    33181 tgctacgcca aatgctgttt tacaagcatt gagcggtaga ttcggttctg aaaactggta
    33241 caaagtgatg atggagatct ttaactataa tacagcacct ggtgctacga tttatacgat
    33301 tctgatcgtt gccttcactt tcttctacgc ctttgttcaa gtaaaccctg agaaattagc
    33361 ggaaaacttg caaaagcaag gaagttatat accaagcgta cgccctggta aggggactga
    33421 agagtatgtc tcaagattac tgatgcgttt aagtacagtt ggtgcagtct tccttggttt
    33481 agtggcattg cttccaatca ttgctcaaat ggtttgggat cttccacaat caatcggatt
    33541 aggcggtaca agcttactga tcgttatcgg tgtagcttta gaaactgcga aacagttaga
    33601 aggcttaatg ctgaaacgta aatatgttgg attcattgag taagaaagcg tgttgaggtt
    33661 tcccctcaac acacgttctc acacatttat taggagggaa aacaatgaac ctcattttaa
    33721 tggggctgcc aggcgcaggt aaaggaacac aagctgaaaa aatcattgat gcttatggta
    33781 ttccgcacat ctcaacagga gatatgttcc gcgcagcgat gcaaaacgaa acagctcttg
    33841 gcctggaagc aaagtcttat atggataaag gtgcattagt tcctgatgaa gtaacaaatg
    33901 gaatcgtgaa agagcgacta gctgaaccag atacagagaa aggcttctta ttagatggct
    33961 ttccacgtac gctagatcaa gcaaaagctc tggacgcaat gctaaaagat ttgaataaaa
    34021 aaattgatgc tgtcatcgat atccatgttg gtgaagaaat cttggtcgaa cgtctagccg
    34081 gccgatttat ctgcagcaat tgtggagcaa cttaccataa aattttcaac cctacaaaag
    34141 ttgaagacac atgtgatcgt tgcggtgggc atgaattcta tcaaagagaa gatgataaac
    34201 ctgagacggt taaaaatcgt ctggctatca acatcaaaaa tagtgaacca atcttggctt
    34261 attataaaga acaaggtttg ctaaacacta ttgatggtgc tcgtgaaatc gatgctgtat
    34321 ttgcagatgt acaaaaaatc attgaaaaat agcacgattg cccgtagccg acttgcatta
    34381 tgcagttact cttgtcaagt tcaataaatt atgatagaat atgtcagtcc gacttctaga
    34441 gaatcctcta gatgatccat tttgagaatt ttgaggtggg aactgcagtt tccgccattt
    34501 tatcgtgtga aaatgcgaaa caagtacaag gaggtactgt gcgtggcaaa agaagatatg
    34561 attgaagtcg aaggtacagt cgtcgaaact ttgccgaatg caatgtttaa agttgaacta
    34621 gaaaacggac accaagttct tgctactgtt tcaggtaaaa ttcgtatgca ttacatccgt
    34681 atcttacctg gtgacaaagt aacggttgaa ttgtctccat acgatcttaa ccgtggccgt
    34741 attacttatc gctttaaata attgtactcc gtaaaactac aggaggtatt atcatgaaag
    34801 taagaccatc agtaaaacca atgtgcgaac attgtaaagt aattcgtcgt aaaggacgcg
    34861 ttatggtgat ttgcccagca aatccaaaac ataaacaacg tcaaggataa ttggaggtgc
    34921 tataaatatg gctcgtattg caggagtaga tattcctcgt gataaacgtg tagtagtttc
    34981 acttacttat atctatggta ttggtaacac tactgctaaa aagatcttag ctgatgctgg
    35041 tgtatctgaa gatgttcgcg ttcgtgaatt aacgaatgaa caaacagatg ctatccgtgc
    35101 agaagtagat aaattaaaag ttgaagggga tcttcgtcgt gaagtgaact tgaacatcaa
    35161 acgtttgatg gaaatcggtt cttaccgtgg aatccgtcat cgccgtggat tgcctgttcg
    35221 tggacaaaac acgaaaaaca atgcacgtac tcgtaaaggc ccagctcgcg ctatcgctgg
    35281 caagaaaaaa taattcttaa gtgaaggagg ttaaaacttc atggcagcaa aaaaagtgaa
    35341 tcgtaaacgc cgtgtgaaga agaatataga agcaggtatt gcacatatcc attctacatt
    35401 caataacact atcatcatga tcactgatac tcacggaaat gcattagcgt ggtcatcagc
    35461 tggttcatta ggtttcaaag gaagcaaaaa atcaactcct tttgccgctc aaatggcagc
    35521 agaaactgct acaaaagcag caatggaaca cggattaaag actgttgaag taacagttaa
    35581 aggacctggt tctggacgtg aagcagcaat tcgttcatta caagctacag gtttagaagt
    35641 gactgcaatt cgtgacgtga ctccagttcc tcataatggt gcccgccctc caaaacgccg
    35701 tcgtgtttaa tgagtgccgc tcattttgag ttttatcagt aacgtcattg aacaagacac
    35761 ttttcgtttt gaaaggggta aagataagaa tgattgagtt cgaaaaacca agaatcgcaa
    35821 aaattgatga agaaaaagat tatggcaagt tcatcgttga acctcttgaa agagggtatg
    35881 ggactacttt agggaattcc ctacgtcgta ttttattatc ttctttgcca ggtgctgcca
    35941 tcactaatat tcaaatcgat ggtgtactgc atgaattctc taccatcaaa ggtgttagag
    36001 aagacgtcac tcaaatcatc ttgaacatta aaggcttagc gctgaaaatg tatggccaag
    36061 aagaaaaaac ccttgaaatc gatattaccg gacctgctac agtaactgct ggcgatatta
    36121 tcgttgatag tgatgtagaa attcttaaca aagatatgta catctgtagt gtctctgaag
    36181 gagctacgtt ccatgctcgc ttaacagtga aacctggacg tggttatgtt caagcagatg
    36241 aaaataaaaa agaagatatg ccaattggcg ttcttccagt cgattcaatc tacacacctg
    36301 ttcgtcgtgt gaactatcaa gttgagaaca cacgtgttgg acaccgtgaa gattttgata
    36361 aattgacgat ggagatttgg acagatggtt caattgaacc gttggaagca atgagtttgt
    36421 ctgcgaaaat catgactgaa catttggata tttttgtgaa cttaactgat gaagcaaaaa
    36481 atgctgaaat catggtcgaa aaagaagaaa cacaaaaaga aaaaatgttg gaaatgacga
    36541 tcgaagagtt agacttgtct gttcgctctt acaattgttt gaaacgtgca ggaatcaata
    36601 ctgtacaaga acttacaaat aaatctgagc ctgaaatgat caaagtccgt aacttaggac
    36661 gtaaatcatt agaagaagtt aaagcaaaat tgcacgactt aggtttaggt ttacgtaaag
    36721 aagattaaaa ccttttacga aggagggaaa ccaacgtgag ttatcgtaaa ctaggacgca
    36781 catctagcca acgtaaagcg atgttgcgtg atttaacaac tgatttatta atcaacgaac
    36841 gtattgtgac tactgaagct cgtgcgaaag aagttcgctc aactgcagaa aaaatgatca
    36901 ctttaggtaa acgcggagat ttgcatgcac gtcgtcaagc tgcggctttc gtacgtaatg
    36961 aagttgccag cgtgcgtgaa gaaaatgagg acatcgtcat tgaatcagct ttacaaaaac
    37021 tgttcaacga tattgcacct cgttacgcag aacgtcaagg cggatacaca cgcattttga
    37081 agacagaacc aagacgcggt gatggtgcac caatggttgt cttagaactt gtctaaaatc
    37141 acactaataa catcacttta tagatgattc ttttagagtg ttatgatgtt ggaagatatt
    37201 tttccgagtc tagctcagcg ctgctcctca agcgaatatc gcttggggag taagcactca
    37261 tcataaagtg tttttttata ccttcaatta cctgtcatga cagatatgtt tgaaggcata
    37321 aaaaaacatt ttaagcgaga aataattgaa aattttgtct ttttttgata gtgttagtag
    37381 gaactttagg atgaagaagg agtaatcatg gagccaatta ttgaattaga aaagataaat
    37441 tataaatacc agccagatga tcttcgcccc gcattgaaag atgtctcctt tacaattgat
    37501 aaaggtgagt ggatcgctat tattggacac aatggttcag gaaaatcgac acttgccaaa
    37561 acgatcaatg gattgcttct gccagaatca gggatcgtga aagtgggaaa tcaaatattg
    37621 gatgaagaaa atatttggac gatccgacag atggttggaa tggtttttca aaatccagac
    37681 aatcagtttg ttggttcgac agtagaagat gacgttgctt ttggtcttga aaatcaaggg
    37741 attcccagag aagaaatgct agtgcgtgtg aaagatgcac ttgagaaagt tagaatggct
    37801 gagtttgctt cacgcgagcc tgctcgttta tcaggagggc aaaaacaacg tgttgccatt
    37861 gccggcgtgg ttgccttacg acctgatatc attattttag atgaagcaac cagtatgcta
    37921 gatccagaag gtcgtgaaga agtgatctct acgatcaaga agatcaaaga agaaagtcaa
    37981 ttgaccgtta tatctatcac tcatgatatt gatgaagcag ctaatgccaa tcggatacta
    38041 gtgatgagac aaggcgaact tgtccgtgaa ggtacaccaa aagaaatttt ttctgctggt
    38101 cctgaactga tcgacttagg tctagatcta ccatttcctg aaaaactgaa gagcgcactg
    38161 aaagaacgtg gggttgatgt gcccagtgaa tatatgacag aagaaaggat ggtggattgg
    38221 ttatggacat ccgttttgaa caagtagact tcacttatca gccgaataca ccatttgaac
    38281 aaagagcctt atttgacatc aatatgacga tcaaagaaaa cagttatact gcattagtag
    38341 ggcataccgg aagcgggaaa tcaaccttac ttcagcattt gaatgcgctt gttaagccaa
    38401 caagcggtac agtccatatt ggagaacgag atattcagcc ggatacggat aataagaatt
    38461 taaagcccat ccgaaaaaaa gttggcatcg tctttcagtt tccagaagca cagctattcg
    38521 aagaaacggt agcaaaagac attgctttcg gtcctaaaaa ctttggtgtc agcgaagaag
    38581 aagcactagt cctagcaaaa gaaacattag aacaagttgg gctggatgaa agctatttgg
    38641 aacgttcgcc atttgaactt tcaggagggc aaatgcgtag agtagcaatc gctggtgtgc
    38701 ttgccatgag gccggaagta cttgtattgg atgaaccaac ggcaggactt gatccccagg
    38761 gcagaaaaga aatgatggag atgttttggc gtcttcataa ggaacagcag atcactattg
    38821 tattagttac gcatttaatg gatgatgtag ccaattttgc agattatgtc tatgtgttgg
    38881 aaaagggacg aatcgttaat agcggggagc cgcaagaggt ctttcaaaac attgaatggc
    38941 taaaagaaaa acaactaggc gtacctactg ccaccgagtt tgcagaagaa ttaatggcta
    39001 aagggatgaa ctttgctacc ttgcctttga cagctgaaga attagcagac gctatcgtcc
    39061 attatgctgg aggaaatgcc catgatgaat aaattgatat ttggtcgtta tatgcctgga
    39121 gattccttga tccatcgatt ggatccccga gctaaattat tagccagttt ttattttatc
    39181 ggaatcattt ttttagcaaa taattgggaa acgtaccttt tgttggcatt tttcacatta
    39241 ctttctgtct tcttgtcaaa agtagatttg aaatttttta tccgaggcat tcgcccattg
    39301 atctggctaa tcctcttcac tgtagctttg caggtcttgt ttacaagtgg cggagaaact
    39361 tattggagtt ggggtgtttt ccatatcact gaatttggtg tgatgaacgg cctctttatt
    39421 ttctgtcgat tcgtgttgat catttttatg tcgactctac tcacgcttac tacaccgcct
    39481 ttggaattat cggatgcgat tgagtacttg cttcgtccat tgaaagccgt acggttccca
    39541 gtccacgaaa tttcattgat gctgtcgatt gctcttcgtt ttgtgcctac attgatggac
    39601 gaaacagaaa agatcatgaa cgctcagcgc gctcgcggtg ttgattttgg tgaaggaaac
    39661 ctagttcaga aaatgaaagc agtcattcct ttgctgattc ctttatttgt cagcagcttc
    39721 aaccgtgcgg aagatcttgc gactgctatg gaagcaagag gctacaaagg tggggaagga
    39781 agaacgaaat atcgtgtatt gcattggcat aatagagaca cgatggttat cattgctttt
    39841 gtattattaa ctgtgctact gatcttttta agaggataaa cgttcagtgg gccgctatct
    39901 attcttttct tgctgatctg tttgcaagaa aggatgcaag cagtgtatga caagaaatat
    39961 tagggtctgt ggcagactaa ggtcacaggc ctctttcttt tatctgaaaa gaaagaacga
    40021 aaaaatttta tagaaaaatc attattccag ataacctttt aggaacaaag gagagaaaaa
    40081 catggtacgt tacaaagcaa tcattgcgta cgacggaaca aattttaatg gattccaaaa
    40141 acagccaaat gggcgtactg ttcaagaaga agtagaaaaa acattacaaa aaatggcaaa
    40201 tggaaaagaa atcacggtct ttggttcggg aaggacagat gccggagtac atgcgatcgg
    40261 gcaagtaatc cattttgatt atccagagga gcgtccgtta gaacgaatgc gtttcgcgct
    40321 agatacccag tcaccagagg atattgctgt aagacaagta gaaattgttt cagaagactt
    40381 ccacgcaaga tatttggtca aagaaaagac gtatcaattt cgagtggata tagggaaacc
    40441 acgcagtcct tttcgacgcc attatgcaag ttattttcct tacccacttg atttggaaaa
    40501 aattcagcgg gcgcttcctg atttattagg gactcacgat ttcacctctt tttgtgcatc
    40561 aggaagctcg atagaggata aaatacgtac gatctacgag gctaagatgg aggtaaatga
    40621 aacaaaagac gaattgttgt ttacatttag gggaaatggc ttcttgtata agatgatacg
    40681 gatcttagta ggaacgcttt tgaaaattgg caatggccga ttgcctgaag atagtatccc
    40741 agatattatt gcgaaaaaag atcgtaatgc agcaggacct acagcacacc ctgaaggact
    40801 ttatttgtat gaagtgaaat atgaataaga ggttatgata gaagtggtca gcttcaagaa
    40861 ataagaaggt atttacgaaa attacttctc aaaattttgc aaaatttcgg cttattttcg
    40921 aagaagctac ttctggaaca ccgtttaagg aagaggtcgt gaaatcagcg ttttgacctg
    40981 agtattagag aaacaaacgg gaaaatagct cctcatattt tgccgtttgt tgagctaata
    41041 ccgaaggtca gctgattgaa caccgtttaa gaaagaggtc gtgagcctgt catttaactc
    41101 tgagtcacaa agagcaattt caaaaaacag cttctcatct ttgatgaata tcgtgacttg
    41161 tggacgaggc gttgataagt gaatcatctt tttgttacct attttttctg taaccaaaaa
    41221 acgatggaac gttgttttga ttgcccttgg tgcggacagt ctgaacaggt tccatcgttt
    41281 ctttattttc tacgtcttct tctgtgtgtg tttcgtggtt gttcttctat tgctggatca
    41341 atcgtgccat aaaaggggcg attgcggtca aggtaccaga cataaagaat aaacaatgca
    41401 atacatagga caaaaaggat tgcacctatc gtaaatcctt caggcaagta actgaaagtg
    41461 acagtatgtt tacctgctgg aacttttatc atcaagaatg cgtctttgaa attgctgacc
    41521 ttgactggtt tcccatcaat tttagctttc catcctttgt cataaggaat agttgtcacc
    41581 aacatggaat cttcagcggt atttacagtc ccagaagctt ttctgccagt ggcttccatt
    41641 tcgacacctt tttctttgat ctgattcatt gcggcttgat aggctacaac atctagacca
    41701 acgactttag gctccatgaa acttatttct ttcgtcccat aaaaacttgc agtaaatgtc
    41761 actgttgtct cttgaggata atagccaaga tcatagtatt gaccagaaat gttgatttgc
    41821 gtttttcgcg atgtaccatt gacagtgatc gtcgcactag aactttctaa ttgcgcaaaa
    41881 ttggttggga acaaacttaa gtaagcttgt gtatttgcag gcacatggac ttcccaagtg
    41941 agctcttttg gctggttatc tgctgtttct gagtaagtga cgccagtcgt tgtctttgtg
    42001 atcgtcgtat tcaactgatt cttcaaagta ggtgtataga atgtaaaata ctgttcattt
    42061 agaccagaca atgtattgat caagtttgtc tgactggtca aattatctgt cactggctgc
    42121 tcaacatcat taacggacaa cggtgcagta aatgctagtg gcaatgcatt gacattctga
    42181 tacagtgtat agtcgccgct ttgaccagct tggcggaagc catatttact gaacgtgctt
    42241 tcgtttttag aaatgttata tttgattcct gtaaacccat ccatcagcaa agtattattg
    42301 ttataacgga tattcaaatt tgtccctctt gaacggaaac ctaatttatc caggtaagag
    42361 gaagaattac gatttcttat agaagaaaac aaactgatac cactgtaacc atagttgatc
    42421 gaatcgtttg cagatactgg atccagattt tccaagcggt aaaacgagtc ggaatctttt
    42481 tttgtttcat ttacaagagc tttcaagtca ggataaggat cagtatataa actgcgggaa
    42541 gcataattcc aatcatcaag aatgccatgg atcatactgt tcgtattgac cagtgcttca
    42601 gcagacatga tcaataataa caatatactc agatgattga atgaaagttt tttatgctga
    42661 taaaatccca cagcaaaagc ataaatccct aagaaaacca ctgtcaatac aaaggaagtc
    42721 atcgtcacat aggtgtagct tccttcaggt ttgatgcccc atgccaccgc aaagagagca
    42781 gctacgacca aaatgattcc taacaacagc ccacgatcgt cttgttctat cttttcccat
    42841 ccttttcctg caagcaggag cactaagaaa gagaacagat aggcataacg gaataaaaac
    42901 atattcggtg catgcatacc atgccagaac aaattcaatg gaacaagata aaaacttgcg
    42961 ataagtatgg cgaaaagact gccgtacaaa aatttatttt tcaacggtac tttccgactg
    43021 gcaaaataaa acagacagag gactaatggt agcagacctg cgtaaacgaa cggaatcgat
    43081 ccgtattttg tcgtgtcata aacaccaatc atatttttca tgattagatc cagataagaa
    43141 gtcgcttctg ttttcaacgt agtgatctga ctcagtgcct cgccatttga ccgaagatcc
    43201 agcactgctg gcaatacaat gatcattgaa gcgccgcctg ccagtaaaga agtgatacca
    43261 taaggaacaa tcgttttttt atattctgac cagtttgtca atagacgggc gataaaatat
    43321 aagaaagaaa atacgccaat cataaaaccc atataaaaac tggataaaaa caagagtaaa
    43381 taactgataa ataaaagttt cggccgttta agatccataa cacgatgaat ccccaaaatc
    43441 actaatggaa gataaacaaa tgcatccagc cacatgatga tctccgaatg tgcagtgata
    43501 aatgagatca atgcgtaact gacgctaagt gcaacatgcc cccagcgagg aatcttgaac
    43561 gtacgtgcaa gaaaccaaaa agccaatccg gcacagccga ccttaagcaa agtcagaaca
    43621 tacagtgcat ctggcatcat ctggtttgga aaaaagaaca ccagtggcgt gaagatcccg
    43681 cctagatagt aagaaattaa agataaataa ttcaatccta gagaagcatt ccatgtataa
    43741 aaaatacttt gctttccaag aagaacattt cggaagctgg catgaaaatt agaaaactgt
    43801 gaaaaggcat cacttgccaa aatacttctg ctgcttccag gatagattcc gatacttaga
    43861 taaacaagtg ctaaaatcaa aaacggaatc aggaaactag ctgctgcgta gcgtccgttt
    43921 tctctaaaga atgactttaa attttttttc atatttattt tccaccaaat ttctatgaag
    43981 ttgtattcag tttatcatat ccttgttttt ctctgcttaa aaagagtcta gttttcacaa
    44041 aaaaataaaa tttagaataa ataacttcat aatttgttcg tataacaaaa ataaacgcaa
    44101 aaaaagggta ggaatcaaaa gtcccaccct taaaaatttt tattaaataa aaaaccgttc
    44161 actatctgaa cggtccaagt atcattcaat taaacgcgtt caacttttcc tgatttcaaa
    44221 gcacgagttg acacccaaac ttttttaggt tttccgtcga ccataacgcg aactttttgt
    44281 aagttaggtt taacagtacg ttttgttgag ttcatagcgt gtgaacggtt gtttccactt
    44341 tttgtcttgc gacctgtaaa gtaacaaact tttgccatgg taatttcctc ctttgccttg
    44401 atttggagca atagaataat tcagctcata ccagactaac atatcatata gaatgggaat
    44461 ttgcaagtac attttcatag atacaattga caattgagaa gaataattgt aaattaaaca
    44521 aggttatacc tgaaattttg caaggttttt gagtactttg ggtaactgcc ttttatttca
    44581 agttgcgcta tgataaaata tgatagaaga aaaatgggag ttttttaccc gttaaggagg
    44641 ctcattcatg gctgtaaaaa ttcaaacgtc agctggaacc attgaaatta ccaatgatgt
    44701 aattgcaaca gttgttggtg gcgccgcgac agatgtgttc ggtgttgtag gaatggccag
    44761 caaaaatcaa attaaagata atattactga gattttgcgt aaagaaaatt actcaagagg
    44821 agtagttgtc cgccaagaag ataatggtat tgctgtagat gtttatacga ttatcagcta
    44881 tggtacgaaa atctctgaag tttcccgcaa cgtccaagaa aaagtgaaat acaatctaga
    44941 ggcattatta ggcgtaactg ccaattcagt taatgtcttt gtacaaggtg ttcgtgtact
    45001 gccagactag gcaggagact ggctggtaac tcagcagtcg atctgaagga ggattatcta
    45061 ggtgagtgta acagaaataa gtgcaagcca gttccaggaa atggtccagg caggtgcgaa
    45121 tcgtctgcaa gtaaatgcag aatacgtcaa ttcattaaat gtattccctg tgccagatgg
    45181 cgatacggga acaaatatga atctatctat gactagtgga gctaaggcag tagtagattc
    45241 aacctcagaa aaagtaggag aattagcagc aatgctttca aaaggattgc tgatgggtgc
    45301 gcgcggaaat tccggcgtta ttttgtctca attgtttcgt ggattttcta agcaaattcc
    45361 agatgttgtc tcattaaatg cttctgatct tgctgcagcc ttcactcatg gagttgaaac
    45421 tgcgtataaa gcagtaatga aaccagtaga aggaacgatt ttgacagtag ctagagaagc
    45481 agcgaaagct ggagaaaaga aagcaaaaag tactgatgat gtcgttgaag taatgacagc
    45541 tgttgtaaaa ggagcaaagc gtgctttagc taaaactcca gacttgcttc cagtcctaaa
    45601 agaagtcggt gtcgtagaca gtggagggca aggactgctg tttgtttatg agggcttttt
    45661 aagtgcattg aatggagaat tccaagcgga tgaaacatat gaaccttctc cagcagaaat
    45721 ggatgatatg gtcaatgcag aacatcatcg cagtgtccaa ggtcaaatgg cgacagaaga
    45781 tatccatttt ggttactgta cagaaatcat ggtaaaaatc ggagaaggac ctacagtcga
    45841 tagtacattc gattacgaag aattccgtaa ctatttagat ggtataggag attctttact
    45901 tgtggtcaat gatgacgaga tcatcaaagt ccacgtgcat acagaaaacc caggagaagt
    45961 cttgaattat ggacaaaaat tcggttcatt agtcaaaatc aaagtcgaca acatgcgctt
    46021 gcagcatgag acgattttgg aacacgatga agaagtgaac gagtttgcga aaaaagaaat
    46081 accacgtatc ccgtatggta tcgtagcgat cgctgctggt aaaggcgtcc aagagctgtt
    46141 tgaaagttta ggcgctaatt atgttatcag tggtggacaa acaatgaatc caagtacgga
    46201 agacattgtt aaagcgattc aagaagtaaa cgcagataaa gtgattgtct tgccaaacaa
    46261 taagaacatc ttcatggcag ctgatcaagc agcagaagta gcagatatcc cagtagcagt
    46321 tgttccttca agaacgattt cccaaggatt gacagctatg ctttcattca atgatcaagc
    46381 ttctttagaa gaaaacaaag aaacgatgac agaaatgttg tctagcgttg tgagcggtca
    46441 agtcactcac gcgatcagag atacctcaat tgacggtgta gagatcaaag aaggagactt
    46501 tttgggcatg atcgatggaa aaatcctgat ctctaaccca gatatcacag caacagcgtt
    46561 aagtacacta gaacaaatga tcaatgagga cacagagatc gtaacgatct tggcaggtga
    46621 tgaaggaaca gttgaacaag caaatgaatt tgctgagaaa ctaacagaaa aacatcctga
    46681 tttggaaatc gagatccacc aaggagatca gcctgtctat ccttatctat tttctgctga
    46741 ataatttctg tgtcagaata tctttctaac acagtattca ttcataaaag gccttcggtt
    46801 agtgatcagg tatgatcgct gaccaagtcc tttttttgtt aaaggaggga ggaaaaattt
    46861 atgcgttctt tagatgatcc aatcactatg ctggcaggag tcggagaaaa aagagcagct
    46921 agtcttgcca gcttgggcat ccaaacgatt gaagacttac tgacttatta tccttttcgc
    46981 tacgaagata ttcaggaaag aaatctaaac gagatccagg atcaagaaaa ggttactttg
    47041 aaaggaatcg tagtctcgcc tcctgtgatg aatcgatttg gttataaaaa aagccgattg
    47101 caatttcgta tgatgcaaga acatgatgtg ttcaacgttt ctttttttaa tcaaccttat
    47161 ctaaaagaaa aagtcatttt atcggaggaa atcgccgtat acggtaaatg ggatgcaaag
    47221 cgtaaagcct tgaacgggat gaagatttta ggttctcaaa caatggatga cttttcgccg
    47281 atatatcacg tcaacaaatc aattcgtcaa acgacattag ttgatctaat caaaaaaggg
    47341 tttcaagaat acggcacatt gattgaagaa aatctgccaa acaaccttgt ggagaaatat
    47401 cgactgcttg accgagcttc tgctgtaaga agtatgcatt ttccaaaaga ccacgaagaa
    47461 aaccatcaag ccaaacgacg tgtcgttttt gaagagttct ttttatttca aatgcgtctt
    47521 caaggattga aaaaagcaga aaaagcagaa acgaatggtt tggagatcct ttatgatgtc
    47581 caaaaattga aacaatttac tcaaaagcta ccttttgaac tgacaaatgc acaaaaacgt
    47641 gtaacgaatg aaatctgtcg ggatcttcgc agtccgcagc atatgcagcg acttttgcag
    47701 ggagatgtag gtagcggaaa aacagtggtt gccgcgattg cgttatacgc taccgttaca
    47761 gcaggtttcc aaggtgcgtt gatggtgcct acagaaatct tggcacaaca acatatggaa
    47821 agcttgcaac agctgtttga tcccaatgaa gtaaccatcg cattgattac ggggtcaacg
    47881 aaagcaaaag aacgacgtga gctccttgaa aaactagagc aaggggaaat taacgtcgtg
    47941 atcggcacac atgcattgat ccaagatgga gtcgaatttc agaatttagg tctagttatt
    48001 acggatgagc agcaccgttt tggcgtgaac cagcggaaag tacttcgtga aaaaggctgg
    48061 cgaccagatg tcttatttat gacagcgact ccgattccta gaacattagc tattacagca
    48121 tatggtgaga tggatgtatc tatcattgat gaacttccag ctggacgtat cccgatcgaa
    48181 acacgctggg taagaacacc tcaattggac agtgtactgg attggacgaa aaaagaactg
    48241 gcaagaggac atcaaatgta tgtcatctgt ccgctgattg aagaatcaga agcattagat
    48301 gtaaaaaatg cagtggaaat ctatgaaaaa cttcgtgaac tatttgcacc aaaatatgaa
    48361 gttggcttgt tacatggtaa aatgaagaat caggaaaaag aagtaatcat ggaagccttc
    48421 aaagacaacc agatgcagat attagtttcg actactgtaa ttgaagtagg ggtaaacgtg
    48481 ccgaacgcga ccgtcatgct gatcatggat gcggatcgat ttggattggc acagctgcac
    48541 caacttcgtg gacgtgttgg acgcggaagt gatgcttcct actgtatctt agttgctaat
    48601 cctaaaaatg aactaggtgt ggaacggatg aaaatcatga cagagaccac caatggtttt
    48661 gtactaagcg aaaaagatct ggaattacgt ggtcctggtg aagtatttgg cttccgtcaa
    48721 tctggtctgc ctcaatttgc gattgctgac ttggtgacgg atggaaatgt tttggaggta
    48781 gccagagaag aggctgcagc cctttggcaa ataaaggatt ggcagatgct tcctgagtat
    48841 cagcctttag cgcaaagcct ccaaatagaa aatcaggata atcgttattt cgattagcag
    48901 actgtgctat actttatact gatgacggaa aaaggagtgg aaacaatgaa aattgccgta
    48961 gatgcaatgg gcggagatca cgcacctcaa gcaattgtag aaggcgtggc tttagcgcag
    49021 caagattttc cagaagtaga attcttactt tacggaaaag aagcagaaat caagaaatac
    49081 ttaacaaatg aaaaaaacat cacgattatc catacagacg aaaaaatcaa tagtgatgat
    49141 gagccagtaa aagcaattcg acgaaaaaag actgcatcaa tggtccttgc tgcacaagca
    49201 gtgaaaaacg gtgaagcaga tgctgtattt tcagcaggga atacaggcgc gctactagca
    49261 gcagggttgt tcatcgtagg acgtatcaaa aatatcgaac gccctggctt gatgtctacc
    49321 ttgccagtag tagggaaaga aggtgccggt ttcgatatgc tggatcttgg cgctaacgca
    49381 gaaaacaaac cagaacattt gttgcaatac ggtattttag gttcttttta tgcacgtaaa
    49441 gtccgaggta tcggacgtcc tcgtgtcgca ctcttaaaca acggaacaga agcaacaaaa
    49501 ggtagtgaag tgacgaaaaa agcctatgaa ctccttcaga atgaaacaag cttgaatttt
    49561 attggaaacg tagaagctcg tgagctactc aatggtgtgg ctgatgtagt ggtcacagat
    49621 ggatttacag gcaacgctgt tttgaaatct attgaaggaa cagcaatgaa tatgatgaat
    49681 ctattaaaat ctgctattct aaatgaaggg atcaaaggaa aaatgggcgc tatgctttta
    49741 aaagacggct tacgttcttt gaaagcagaa atggattatt ccaaacatgg cggtgccgtt
    49801 ttgtttggct tgaaagcacc agtcattaaa actcatggag caacaggccc cgatgctgtt
    49861 cgctatacga tccgccaaat ccacacaatg cttgagacag atgtagttgg acaattagtc
    49921 gaacaatttg aaaaaagcga agaatagtat ttggatatct gaagcgatcc gttccattga
    49981 aaaaaaggtg gacattcctg aaaaatgcca gtaaaattag ccatggtgta ggtaattgac
    50041 aagtgtatga ttcttggagg tgaaaaagtt gactcgcgaa gaagtattta acaaagtagc
    50101 gaaaattatt tcaaatcatt ttgagataga taccgataaa gtgacggatg aattgaacat
    50161 caaagatgat ttaaaagctg attcaattag tattatggaa ttcgttttag agcttgaaga
    50221 tgaattcggt acggaaattt cagatgaaga cgctgaacaa attgaaacag tcggtggcgc
    50281 agtagattat atcagcagcc atcttaaata atttcaaata aaagcaaaga aggataaaaa
    50341 gctgcatgca gctttttatc cttctttttt taatcttttt gacacgtaaa agtcattttt
    50401 ctgataattc tggcgataaa cagaaattat gttgcaaagt aaagcggttt tctatataat
    50461 tattaataat tcattacaca aagataagaa taacctttgt tataaaacga tttattctgt
    50521 gtaatgtcct tttttattaa gaaaaacttc catttaggaa gcagagaggg gtattcgatt
    50581 gtccgataac caattattag aagttcagaa cctacataca ggattccgac tcaaagatga
    50641 ctattacgat gcagtagatg acgtttcatt tactttagac aaaaacgaga ttttagcaat
    50701 cgttggggaa tctgggtgcg ggaaaagtac cttggctact acgattatgg gattacttga
    50761 tcctaataac acaaaaatta caggtgagat tttatataac gatctgaatt taatcgacct
    50821 gaacgaaacg ctctataata aaatccgcgg aaatgatatc ggaatgattt tccaagatcc
    50881 gttgtctgca ttaaatcctc tcatgagaat cgaagaccag atcaaagaag gactttccta
    50941 tcacacaaag atgaatgcag aacagcgtca agctcgtgca ctagaattgc tagaacaagt
    51001 agggattcct aatcctgcga gagttggacg ccaatatccc catgaactat caggcggtat
    51061 gagacaacgt gtcatcatcg caatcgcaat cgcctgcaaa cctccaatcg tcattgcaga
    51121 tgaaccgacg acagccctag atgtaaccat ccaagcacag attcttgatt tactgaaaga
    51181 ccttcaggaa gaaacaaaaa cagggatcat cttgatcact catgacttag gagtcgtagc
    51241 agaaatggct gatcgagtgg cagtgatgta tggcggacag ttcgttgaag tagcaggtgt
    51301 aaaagaactg tttgatcatc ctaagcatcc ttatacacgc tctttactga actctatacc
    51361 acaagaagga aatcatgatg cagaactcca tgtgatcgaa ggtgtcgttc cttctctgaa
    51421 aaacatgcct cgtaaaggtt gtcggtttgc accacgtatt ccatggatac cagcaagcga
    51481 tcatgaagaa gagcctatcc ttcatgaagt cgcaccgaac cacttggtac gttgctcctg
    51541 ctataagcat ttccacttta gagacgaaaa aggagaggtg tagatgacag aattaatcac
    51601 aatcaaagac ctgaaagttc attaccctat tcgcagtgga ttcttcaatc gagtaacgga
    51661 tcatgtatat gctgtagatg gtgtggattt tattatcgaa aaaggaaaga catatggttt
    51721 agtgggagag tctggctctg gaaaatctac tacgggaaaa gccgttgtgg gattagaaaa
    51781 ggtaacagcc ggacaaatca tgtatgaagg aaaagatgta acgaagcgaa gcaaccgcaa
    51841 aaaaatgggt tataacaagg atgtgcagat gatcttccaa gattcaatgt ccagtttgaa
    51901 tcctaaaaag cgagtgttgg atatcattgc tgaacccatc cgaaattttg aacggttaag
    51961 cgatcaagaa gaaaagaaaa aggtaaaagg actgctagat atcgttggga tgccggaaga
    52021 tgcgctatat aaatatcctc atgaattttc aggcggacaa cgtcaacgtc taggagtagc
    52081 ccgtgctgtt gctaccaatc caaaactgat cgtagccgat gaacctgtat ctgctctgga
    52141 tctatctgtt caagcgcaag tattgaattt catgaaacga atccagcaag aatacggcct
    52201 cagctattta ttcatttcac atgatttagg tgtagtaaaa cacatgtgcg acaatatcgc
    52261 aattatgtac aaaggtcgat ttgtagaaat cggtacaaga gaagacattt ataatgaccc
    52321 gcgacatatc tatacgaaac gtctgctttc agctattccg caaatcgatg tagaaaatag
    52381 ggaaagccac aaagaaaatc gacgaagagt agaacaagag tatatccaaa accaaaaaga
    52441 atactatgat gcgactggtc gagtctacga tttgcgtacg atcacaacta cacacaaagt
    52501 ggcgttgaaa gatggaggtg caagctaatg tggaaaacga ttctgcgacg tgttttattg
    52561 atgatcccgc aagttattat tttaagtgtt ctgatcttct tattagccca agcgatgccg
    52621 ggggatccat ttaccggttt gatcaatcca aatcaggatc cggcagtgat cgaacagatg
    52681 cgacaagcag ctggcttgaa tgacccatgg tatgtccagt acttccgttg gatcggaaat
    52741 gctttgcaag gcgattttgg tcaaagtttc ttatacaaac gctctgttgc tgacttgatc
    52801 ggcgaacgga tcatcaacac tttatatcta tcgatcttga cagttgtcct tacttatttg
    52861 attgctgtgc ctctggggat gcttgctggc cggtatcaaa attcaatctt ggataagatt
    52921 gtcgtaatct acaacttctt tagttttgct gttcctttat ttatcttcgg cttgatcatg
    52981 ctatttgttt ttggttatcg tttaggctgg ttcccaacaa gtggatcaca aacactaggt
    53041 ttgcaaggtg gatttatcac tcaatggata gaccgtttga aatatattct gttaccatca
    53101 attacccaag catttttggc gactgccgtc acaatccaat atctgcgaag tgaagtaatc
    53161 gattcgaaat cgctcgattt tgtcagaaca gcccgttcca aaggggtacc gacgaataaa
    53221 gtattcagtc gacatatttt ccgaaatgca gcgttgccga tggcttctca aatggggtat
    53281 gaaatcactt cgttgattgc tggttctgta gttatcgaaa agatttttgg ttatccggga
    53341 gtcggaaaac tatttattga ttccatcggc caacgggact ataccgtgat cacatcctta
    53401 gtattgattt taggaatcgc gacgctagtg gggacattac tttcagatat catcatgagt
    53461 atcgttgacc cgcgtattcg gattcaataa aaccaatcag aaaggagaat ggatcgatga
    53521 gtgaaaaaaa caatacagca gttcaagaaa gtattcctcc tatggggata cgaatgattg
    53581 ctcgagaatt taaaaaagat aaaattgcta ttttttcatt aggtttgcta gtggttttat
    53641 tattagtgat ctttatcggt gcgatgctga ccgatcaaga caaagtgatg tatgttagta
    53701 tcttcgacaa atacgctgca ccaggaacag tttcgacaca aggacaaaag ttcattctgg
    53761 gagcagatga aggcggacgt gatgtattag gacaattgat cataggtgct agaaactctg
    53821 ttacgatcgg atttgcgatc acgatcctta cttcgatcat cggggttgga ttagggatca
    53881 tctctggcta ctacggaggg atcattgaca acatcttgat gcggatcgtt gattttatca
    53941 tgattctacc gatcatgctg atcattatcg tcttcgtatc gattatttcc agatacaatg
    54001 tctggtcctt tatattcatc atgagtgcat tttattgggt agctaaagcc cgattattcc
    54061 gaagcaagac attatctgaa gcaagaagag attatgtcag tgcctcaaaa acaatgggaa
    54121 ccaatgattt taaaatcatg ttccgcgaaa tcatgccgaa tctaagttca ttaatcatta
    54181 ctaatttgac gatgaacttt gcggcaaaca tcggtatcga gacaactttg actttcttag
    54241 gtttcggctt gccggcaaat gtacctagtt taggtacatt gatcggttat gcaagtaacg
    54301 gagaagtctt agtgaatcgg caatggatct ggttacccgc atcaatcctt attttagttt
    54361 tgatgttgag tatcaattat gttggacaag cattcaagcg ttctgcagat gcgcgccaac
    54421 ggttaggcta gtatagaagc gaagggggaa ataggaatga agaaaacgat ttttggattt
    54481 gcagcgctga tgtctgctgt cgttcttgca gcatgcgggg gcggaggtac agatacctct
    54541 ggaaacaact ctggaggcaa cggcaataac aaagaggaat taacttttcc aattgcaaca
    54601 aaaaataatg atgatgcaat cgaagacggc gaattagaag ctgcggtcgc aacggacagt
    54661 cagtttaaag gattgttcca gtgggagttt taccaagatt catatgatgc agcttttatg
    54721 gctccttctc atgaaccgct atttgcaaac gatgacgatt tcagaatcac agacgacgga
    54781 gctgcaacgc ttgatctaga tgaagatacg aaaaaagcga caatcaaagt aaaagacaac
    54841 gtcaaatggt cagatggtga agatgtaacg gcggacgatg tgattttccc ttacgaaatc
    54901 attgggaata aagattacac tggtatccgt tatgacgaca ctttccgtaa catcgtaggt
    54961 atggaagaat atcatgatgg aagtgccgac acaatctccg gaatcaaaaa aatagacgac
    55021 aaaacagttg aaatcgaata taaagaagta aacccaagca tgcttcaatc gggtggtggt
    55081 atctggtcat atgcagcacc aaaacatacg ttagaaggtg tagcaatcaa agatatggaa
    55141 tcaagcgatc aagtacgtaa aaatccagtg acttttggcc cttattacat gagtaatatc
    55201 gttgcaggag aatcagtaga atacttgcca aacgagcact actggaatgg tacgcctaaa
    55261 ttgaaaaaga tcacgatgaa atctgtaccg atggcaagtg caactgaagc attgaactct
    55321 aaattatatg atatgatttt ccaaatgcca acagatactt acgataccta taaagaaatt
    55381 gctggctata caaacttagg ccgtgaacaa acttcttata cttatctagg attcaagtta
    55441 ggtaaatgga atgcagatac aaagagtgtg gaatacaatc cagattcaaa aatggctgat
    55501 aaatcattac gtcaagcaat gggctatgca ttagataata atgcagtagg tgaacgtttc
    55561 tatgcaggtt tgagaagcaa tgcgacttca ttgattcctc cagtattcca gtcataccat
    55621 gatgatgaga tgaaaggatt cacacaagat ctagacaaag cgaaaaaact attagatgat
    55681 gctggctaca aagatgtgga tgacgatggt ttaagagaag acaaagatgg aaataaacta
    55741 acaatcaact ttgcttcgat gtccggtggg gaaacagcgc aaccattggc agattactat
    55801 atccaacaat ggaaagaaat tggtttggat gtccaataca caacaggtcg tctgatcgaa
    55861 ttcaattctt tctatgataa attagaaaac gatgatcctg aaattgatgt ttaccaagct
    55921 gcttggaata caggaactga tccaaatcca agtggactat ggggaccaaa tgctgcgttc
    55981 aactacactc gttatgaatc agaagaaaat acaaaattga tcaacgatat cagttcaagc
    56041 aaagcatttg atgaagagta ccaaaaagaa gcatatcaaa aatggcaaca atatgcattt
    56101 gaagaagcat ttgcgattcc aacgttgttc cgtaatgaag tattgccagt caacgaccgt
    56161 gtcaaagact gggattggtc ttatgatgta ccaaacccat gggcaaatgt ttctgttaca
    56221 gcagattcac gttcataatc actaaaaatg accgaaaaag ggcgatgtcc tttttcggtt
    56281 ttttgatatt tttctgttta tttctctaat attcaggtca aggcgctgat ttcatgactt
    56341 ctccaataaa cggtgttcaa agtccagttt ctcggtatta agtcaaattt atgcaaaaat
    56401 atggaaagcc attttcacaa aattttttct tcatactcga aactaaacga atttttcaca
    56461 acttctcgtc aatcactagg attattaaag ctttacttac cttttgaccg aaccatttca
    56521 aatttgacaa aaaaccagta taataaggaa gtatcgaaaa aatatccata aaaggaatgt
    56581 ggaaaatgga caaccagctg acaaaagaac taaaagaaaa ctataacatc gtttttcacg
    56641 atctaaattt gcttgaacaa gcttttaccc attcatccta tgtgaatgag catcgcaatc
    56701 tgcaattatc ggataatgag cgacttgaat ttttaggaga tgccgtttta gaactgatgg
    56761 tttctcagta tttattccgt ttatatcctc atttgccaga aggaaaattg acaaaaacac
    56821 gagctgcgat cgttcgcgaa gacagcttgt cgaaatttgc caaagaatgt cactttgatc
    56881 aatatgtttt gttgggcaag ggagaagaga attcaggagg acgtacgcga ccagcattgc
    56941 tttgcgacct attcgaagct tttttaggcg cgttatatct tgaccaggga ttcgacacga
    57001 cccatgcatt catcgaaaaa gtgatttttc ctaaagtcaa agcaggtgct ttttcacatg
    57061 agatggatca taaaacaaaa ctacaagaag tcttgcaaaa atcaggtgat gtatcaatcg
    57121 aataccgatt gatcaatgaa gaaggtccag ctcatgaacg agtattttgg atcgaagttt
    57181 atgtagatga tcaattgatt ggcactggac aagggaaatc gaaaaaatta gcagaacaag
    57241 ctgcggcgga aaatgcattg gcagcactgt aaaagtaagt gagggaaagc tttgtatttg
    57301 aaacgaattg aaatagccgg ttttaaatca tttgcagaca agacagtcat tgattttgaa
    57361 aatagcgtca cagcagtggt tggaccaaat ggcagcggaa aaagcaatat tacagaggct
    57421 atccgctggg tattaggaga acaatctgct aaaagtctgc gaggcggaaa aatgccggat
    57481 atcatctttg ccggttccga tacccgtaag cagctgaata ttgcagaagt cacagtgatt
    57541 ttagacaata gtgatcatta tctgccattg gagtacaatg agatcagtgt aacccgccgt
    57601 tatcgacgga ctggggaaag cgagtttttc atcaataaac aaagctgcag attaaaagat
    57661 atccaagaat tgttcttaga ttctggatta ggaaaagaat cgttctcaat catttctcaa
    57721 ggaaaagtag aagcgatttt cagtagtaaa ccggaagacc gtcgtgggat ctttgaagaa
    57781 gcagctggtg tcttgaaata caagcagcgg aaaaagaaag cagaacagaa gctttttgaa
    57841 acagaagaca acctcagccg cgtccaagac atcatccacg aattggaaga acagttaact
    57901 cctttggccg cccagagtga ggcagcaaag gagtttttac ggctaaaaga aacactgact
    57961 caaaccgatg tctctttgat ggttgctgaa atcaagacag caaaaaaaga ttgggacaac
    58021 aaacaagcac agcttgcgaa attcaatcta gaattaggca aactatctga gtcgatccaa
    58081 gaacaagaat ccattttggc gaagcagcgt aaagaaaatg cgcaagccga tcgtctgatc
    58141 gaaaaaaatc agcaagtatt attagatctt tcggaaaaac tgaagcagac agaaggacaa
    58201 aaagatgttt tgcaggagcg gacaaagcat acacaaaaaa gctcgcaaga atatcaaact
    58261 tcattagcag aagcacaaaa aaaggttaaa cattttgaaa agcttcaaga aagcttgatg
    58321 aaagcagcag cagaaaaaga aacagagatc caaaaagctg aagcaaatct cataaaaaca
    58381 cagcaagaat tagaaaaata ccaaaaatca acgaaagaat tattggcaga attaagagat
    58441 caatatgttg atttgatgca agaacaagca gctgtaggaa acgaactgaa gtatctagaa
    58501 cgtcaatata tacaagaaac agcaaaaagc aagcagacgt tagccaagca atcggaagta
    58561 gaagcatcag tagaccgatt gatcttacaa aaagaagaat tgacacaaaa gcaggcgcag
    58621 ctaaaatcat ctttaactga aacaaaagag aagttagaaa tgatccaaca aaacgggaaa
    58681 aagttccaag aagcattagc aaaagaacag cctaaaatgt atcaattaat gaatcaagtc
    58741 cagcagctac gtgctcgtaa gaaaagcctt caagaaatcc aagaaaacta ttttggtttt
    58801 taccaagggg ttcgattggt cttgcagcat aaacagcagc tttcgggtat tgtcggagca
    58861 gtggctgaac tgatcgatgt tcctgcagat ttcacgttag ctatcgaaac agctttaggt
    58921 ggggcagccc agcatgtcat cgttgaaaat gaaaaagatg ctcggcaagc catcacgtat
    58981 ttgaaacagc aaagaggagg aagagcaaca ttccttccac tgacgacaat caaaccaaga
    59041 caattaccgg ctcatatatt gacacaagca gcagctgtag aagggtttat agggattgcc
    59101 agtgaacaag tcagttatcc cgatcaaatc caaactgtgg ttcaaaacct gctaggaacg
    59161 atccttttag ccaaagactt aactagtgcc aatgcaatcg cgcaaacgat ccgctatcaa
    59221 tatcgagtgg tttccttaga aggtgatgtg atgaatgccg gaggatccat gacaggtgga
    59281 gcgaataaac gaggaaacca aggcagtttg tttgtacaaa atcaagaatt gaaacagttg
    59341 actagtgaat ttgaagaagc agataaacaa ctccaagcac aagaaaaaaa agttcaggag
    59401 ctgcaacaag aaacagctcg tttagccgaa gaacaagaag ttttgcgtac acgaggcgaa
    59461 caattacgtt ttgaagaaca agaagcgaca aatcagctac aaaacatcat aaatgaactt
    59521 gaacgttttg aaaaagaaaa gcaaatctca acttttgaga cacgtgaact gcagcagttt
    59581 atcgaagatt acgaaaagca aacgaacgaa ttgaaagaca aacaaacaga tcttgaatcg
    59641 caacgacaaa aaatcgacga agaaatcaaa tcgttaagtc aagaaagcga ccagatggaa
    59701 gccagaagag cacaagtaca aagtcaaaaa gcacaagaac aagcagatct tgctgtcttg
    59761 aaagagcagt ttaatcatct gcagatccag ctccgcggtg cccgagtcca aaaagcagag
    59821 gcaaccgaac gtcaagaagc gatagaaaag cagttggcga cattgacagc agacttttct
    59881 gatcatgaag tcacagaaga aagtttggaa aaacaaatta acgaattatc tgctcagcga
    59941 gaaacattaa aagccgagtt ggcaaaagcc aaagagcagc gagatagaag gcaaaaggag
    60001 atcgataagc ttgaagcagt cttggcagag cgtaatcgtg agcaaaaagc acgactgtcg
    60061 gaacaatcca aattagaagt ccaaaaagac cgagctgaaa tgattttaga taatcatttg
    60121 acctatctgc agtcagaata tcagctgaca tttgagaaag cttcccaaga ctatcaagaa
    60181 acaaccgata tcgaagacag tagaacaaag gtttcatcct taaaagaaca gattgaaaaa
    60241 ctgggaccag taaacttaaa ttcaatcgaa caatacgaac aagtcagtga aagacataca
    60301 ttcttagcaa cacagcgaga tgatctgtta gcagcgaaaa accaattgtt tgaaacgatg
    60361 gatgagatgg atgatgaagt gcggacaaga ttcaaagaag tatttgaagc tatccgtcaa
    60421 gaattcaaaa ttgtctttcc aaatatgttt ggcggcggta aagctgaatt agtactgacg
    60481 gaaccaactg atttgctgaa aacaggtatt gagattgaag tacaacctcc tggcaaaaaa
    60541 ctgcaaagtc taagtttgct ttctggagga gaacgagcac ttacagccat cgcgttgctc
    60601 ttttccatta tccgtgtctg tcctgttccg ttttgtatct tagatgaggt agaagcagcg
    60661 ttagatgaag ccaacgtgaa acgttttggt cgttacttga gcgatttcca agatgacaca
    60721 caatttatcg tagtcacaca ccgcaaagga acgatggtcg cagcagatgt actgtacgga
    60781 gtgacgatgc aggaatccgg tgtatcaaaa atcgtttctg tacggatgga agatatcaat
    60841 gaagaggcga aaatcaacga aacgaaagtg taggaacgaa aatgatcaaa ttagtagcaa
    60901 tcgatttgga cggtacatta ttaaatgaac aaaagctgat ttcagatgag aataaacaag
    60961 cattagcaca agcaaaacag caaggggtca agatcgttct atgtacagga cgccccttag
    61021 ctgcgatggc gcattatctg caagaattag gactggtaga tgaaggtgac tacagcatca
    61081 ctttcaacgg cggtttggta caaaaaaatg atactggtga aatcatggaa aagaaagtga
    61141 tggaagtatc agatatccaa cgcttataca aactggctca gcaattggat ctgccactag
    61201 atgttttgtc tgacaatgtg gttttacagc tgcctagtgc cccaaggaag caatccttgt
    61261 acaatgtgtt gaataagctg ctgcaattcc aaccagcgga tataagcgat attacagatg
    61321 aatttgtgct taataaggca gtaatcgctt atgaccaaga agaattagat cctaaaatca
    61381 aagaaatacc agcagaattc catgaaatgt atgagatcat caaaacaaga agtatgcttt
    61441 tggaatttat gccaaaaggt gttacaaaag cttatggtat ttctttattg gcaaaagatc
    61501 ttggtttgaa acaagaagaa atcatggcga tcggtgatga ggaaaatgat ttaccgatga
    61561 tccaatatgc tggactaggc gtagcgatgg agaatgctgt gcctttcgtc aaagaagcag
    61621 cagatttcgt gacagccagc aatgaagaaa atggcgtagc caaagtgatc caaaaatttg
    61681 tattagagta gggggagtca aatgggattt tttgataaaa tcaagcgtgc ttttactggc
    61741 gaagagaaaa cagaagaagt tgaagtacag gagaagtacg acaagggttt agaaaagacg
    61801 cgtaaaacat ttggtgaacg gatgaatgag ttgtttgcca attttcgaac agtcgatgaa
    61861 gacttttttg aagaattaga agaaacactt atcggtgcag atgtaggttt tgaaacagcg
    61921 atacgaatca ccgaagcatt acgtcaagaa gtgaaactca gaaatgcgaa aaaatcggca
    61981 gaagtccaaa atgcgatcat cgagaaactt gtggatctct atgaagcgga aggaatcaat
    62041 gaagtaaatg aactaaatat ccaagaagac ggactaacag ttattttgtt tgtcggtgtt
    62101 aatggtgtag ggaaaacaac aagtattggt aaacttgccc atcagttcaa aaacgaaggt
    62161 aaaaaagtat tgatggcagc agcagatacc ttccgcgctg gagcaatcga ccagttagtt
    62221 gtctggggcg aacgcgctgg tgttgaagtt gttcgtggca atgcaggagg cgatccagca
    62281 gctgtcgtat tcgatgcttt ggaaagagca aagacagagc aggcagatgt tttactagtt
    62341 gatactgcag gccgactgca aaataaagtg aacttgatga acgaattaga aaaaataaaa
    62401 cgagtaatcc agcgggaatt accagaagca ccccaagaaa cacttcttgt attagatgca
    62461 accactggtc aaaacgcgat ggttcaagca aaacaattca aagaaacaac agatgtgacc
    62521 ggtcttgttt tgacaaaatt agatggtaca gcaaagggcg gtatcgtact tgctatccgt
    62581 aatgaattgc atttaccagt gaaattggtc ggtcttggtg aaggaatcga tgacttggag
    62641 ccgtttgatc caaatgattt tgtcgttgga ttgttcaaag gattactaaa agaagaataa
    62701 cccatgtcta aaaagcagga gctgtgacaa aagttgcagc tccttgtttg aatgattgtt
    62761 tttaacatag ctgtgttttt gatgccttca tttttatact tatttgtaag cggttctcaa
    62821 acaatttcgt tctttttctt agactttttg attataatta gattcatatg aattggaggt
    62881 cacttaatga tgaattttaa gcaattatta ttgcatgtca atgcgcgccc ttttatcgac
    62941 caagctcgat ttggtataga acgggaagga cagcgggttg atcttgcagg aaatctagca
    63001 aaaaccgatc atccagcaat ctttggcgat cgatcctatc acccctatat ccaaacagat
    63061 tttagcgaaa cacaaacaga gatgatcacc cctgttaccg attctattcc cgaattattt
    63121 cagtatctcg ctgctgttta tgatgtgact gctcgttcta taccgaaaga agagatgatc
    63181 tggccattaa gtatgccacc tgccttaccg gaaaaagacg aagagatcat tattgcaaaa
    63241 ttaaaaaatt tcgaagatgt cttgtatcga cgttatttag caaaagaata cgggaagcga
    63301 aaacagatgg taagcggtat tcatttcaat tttgaatttg gcgatgagtt gctaagaaca
    63361 ttgttcagcc atcaggaaga atttcaagat ttttccgaat tcaaaacaga actttatttg
    63421 aaaacagcga gaaactttat gcgctatcgc tggatgatca cttatttatt cggtgcttca
    63481 ccaatgagtg agaagaacta ctttttagat gaatcacatc cgcaagaacc tgttcgcagt
    63541 attcgcaaca gtgcgctggg ctatacgaat catccaaatg tgaaagtttc ctatgcttct
    63601 atgaaacagt atttagcaga tatcgagcga atgatcgaag aagggaaact ttcggaggag
    63661 aaagaatttt atacaccgct tcgtttccga ggcggaaaga aagtcgcaga tttagcaaca
    63721 acaggtgttc gttatattga attgcggaat atcgatttga atccttatgc aagattgggt
    63781 atcaatccag agcaagttcg gttcttacaa ttattcctga tgtacatgtt atggacagaa
    63841 gaaaaagaag actgtgacca atgggtagca gaaggtacga ctcgaaataa caaagtagca
    63901 ctagaacaac catcagatca aacagaattt catcaagaag gtagagaaat tcttgaagga
    63961 atgaagcaaa tgctggttga attggattgg ttggattctc tttatttagt agaggaagca
    64021 ttgactcaaa tggatcatcc tgaacaaacg ttagcagcga aactctatca agaagcacag
    64081 ctatcgagtc agcaagaagt tgctgtggca ttgggacatc aatattataa agaaagccat
    64141 gaacgtccct atcagttggc cggttttcgc gaaatggaac tttctactca gatatttatg
    64201 ttcgatgcca tccaaaaagg tgtccaagtc aaagtattag atgagtcgga tcaatttttg
    64261 cgtctgcaat tccaagacca tgtagaatat gtgaaaaatg caaacatgac aagtaaggac
    64321 agctatatcg tcccacttat catggaaaac aaaacagtaa cgaaaaaagt cttaaaagaa
    64381 gctgggttcc gggtaccagg aggcgcagaa ttttcatcca tggaagaagc ggtaaaagct
    64441 tatccgagat ttgccgagca ggcatttgtg atcaaaccta aatcaaccaa ttacgggtta
    64501 ggtatcacga ttttcaagga aggagctagt ctggaagatt atcaagcagg tttagccatt
    64561 gcttttcgtg aagacagttc ggttttagta gaagaattta tgccgggaac ggaatatcgt
    64621 ttctttgtga tcgacggaga agtccaagcc atcatgttgc gagtccctgc taatgttatt
    64681 ggtgacagta tccgaacagt gaaagaactt gttgaagaaa aaaatagtga ccctttgcgt
    64741 ggaacgaatc atcgtgcacc tttagaattg atccaattag gtgaattaga acaattgatg
    64801 ttgaaagaac aagggttgac gatcgaatca gttccccaag ccaatcaaat tgtttatcta
    64861 agggagaact caaatatcag tacaggtggt gattcgatcg atatgactga tgaattttct
    64921 gaagcttaca aaaaaatcgc cgtttctgcg gtagaagcac taggagctaa gattagtggt
    64981 atcgatttga ttataccaga taaagaaatc gatcctacaa ctgataaaaa agcatatggg
    65041 atcatcgaag caaatttcaa tccagccatg catatgcatg tttatccttt tgcaggaaaa
    65101 ggcagaagat tgacgatgaa tgtattgaaa ttgttatatc ctgaagtatt ttaaaagaaa
    65161 aagcttttga cagattgtcc tatttgatgt caatctgatc aaaagctttt tttgcatgta
    65221 aaaatttatg tgttttttcg ttttaaaata aacgatccca gaagcttttt ttcttttttg
    65281 gtttttcttt ttcagctggc gaagagtttt cttctgggta ttttttttcg atatcaatca
    65341 caggttcatt tactgcttct tttgctgtta agagcaatcc gaattcctca ggatttgcag
    65401 tgacgtaatc gttgactaca gtgaaacggc tattgttttt cgttgctagc tggatatatt
    65461 ggttttggac agaaaggggt agagccccat tcaagagtat ggaagcatct ggatgttttt
    65521 tgagttcttt taaaaagttt tctttgtttt ttggttggat catttcagca acagtcatac
    65581 taagatagca gcgttccctg aatgtcccta aatatttatg ctgttcttca gggttcacta
    65641 aaggtgtacc ataaagtccc ttatccaaat ggctttttac atcatcttgt gccataaaaa
    65701 ataccctcct tcttctcttt gtctttctta cgattatagc atattcccaa taatacctaa
    65761 aacatatgaa aaagcggttg cttttgttca acgattcact taaaataaga atgaaaatca
    65821 ttctcaatta gaaaggtgga ttggatgcgc tacggacgac tagtagcatt attagttatt
    65881 ttaagtagta tttcattgtt catcggagta tcgaatgtac aattgtcaga actgctccag
    65941 ttagatgggc aaagcttaca aatcttgcta gtgactcgtt tgccacgaac gatttgtttg
    66001 atccttgtgg gagcgaccag tagtatttgt gggttgatca tgcaacattt gacccaaaat
    66061 aaatttgttt caccaacgac tgcgggcacg atggatagtg cgcgtttagg tattttagtg
    66121 gctatgattt tcctacctgg tgcatccttg attgtccgat ccttgacagc attttgcttt
    66181 gcttttgcag gaacattgct ttttttatcc cttacgcgat tgttcctcca gaaaaatcaa
    66241 ttgatgcttc cgttgattgg agtcatgtta gggaatatca ttggttcagt tgctactttt
    66301 tttgcttatc aattccagtt ggtacaaaat atgacttcat ggcttcaagg gaattttgcg
    66361 actgtgatac gaggaaatta tgagttattg tatgctgttg ttccattgtt gctcttggtt
    66421 tggctatttg cttaccgatt tacgatcatt ggtctgggcg aatcgtttgc agtaaatctg
    66481 ggaatagatt accagaagat gcagttttta ggcattggct tagtatcatt ggctagtgca
    66541 gtcatgttga tcatggtagg aagcattcct tttatcggag tgatcattcc gaatcttgtc
    66601 tctagaatat atggagatca agtgcacaaa acaattggcg taactgcttt agcaggtagt
    66661 ttgttcttag tattttgcga tcttgtcgct cgcgtgttga tttttcctta tgaaatacca
    66721 gtcagtgtga tcgttggaat catcggtggg gctatcttcc tttatcttct gataagggga
    66781 cgacgatatg cttaaaaaaa agccatctat ttttattggt atgcttgttc ttgttttatt
    66841 tgttacagga atgtacttga cgatccatac atatggaaac tggcattttg catgtgcatt
    66901 gaggagtaag aaaatttttg catttatcct tgtctcgcta gctgtcagca gtgccacaat
    66961 cagctttcag acaattacgc ataaccagtt tttgactcct tcagtattgg gacttgagtc
    67021 gttatatgtc cttgtccaaa cggtcctttt cttctttatc ggaggagtga cgatgcttca
    67081 gcagacaggt acagtttttt tcttattgaa cgttgggctg atggtcgggc tgagtctatt
    67141 gttatttttc tttcttttga aaaaaatgag agcgaatctt tttttattac tgatgtcagg
    67201 gatgatttta ggtacgcttt ttggtagtgt cagtaccttt ttacaagtca tcatggatcc
    67261 gaatgaatat gatttgcttc aaggcagatt atttgcaagc tttggcaata tccagagtca
    67321 gtatcttttg cctgcttctt tgatcattat cggctgctgg tacctgttat ttcgatatcg
    67381 acatgtgcta gacgttttcc atctcggaaa tgaacaagca gtaaacctcg ggatagacac
    67441 agatcgtttt gaatttttga ttttatgttg tgtcagtctt ttgacaggga catcaacggc
    67501 tcttgtgggt ccagttactt ttttagggtt tattgtcgca aatatcagtt atcgtgtctt
    67561 ttctacttat cgtcatggtc agctatttat cggaagcttt ctggtagcta tgctgtttct
    67621 gacaggagga cagctcgcag tagagcagat tttcggctgg aatacaacag tgagtgtcgt
    67681 cgttgaattt gtcggaggaa tttattttgt cacaaaattg attcgcgaaa ggaagagtat
    67741 cctatgattg atttacaaaa ggtcaataaa ctgtaccatg gaaaatcagt ggttaaagat
    67801 gtacagttaa cgattcctga aaagaagttg actgctttta tcggtccaaa tggtgctgga
    67861 aagtcaacgg tgttgtcgat gatcagtcgt ttgataccaa aagatacagg tgaaatctat
    67921 ttagaccata acgaagtaaa ggcttggaaa tccaatgaat tagccaaaaa attatcgatc
    67981 ctacgacaat cgaatgaaat aaatgtccaa atcaccgtga aagaattagt agaatttgga
    68041 cgatttcctt atacgaaagg aaaattgacg acaaaagacg aggaaatcgt tcaggaatca
    68101 ctggaacacc ttgggttaga agaaatagcg gatcaatcga ttgacactct ttcaggcggt
    68161 caactccaac gtgcgtatat tgcaatggtg ctagcgcaag acacggatta tattttactg
    68221 gatgaacctt tgaacaatct agatatgaat tttgcggttc aaatcatgca gattttaaaa
    68281 aatttagtac aagaaatcgg gaaaacaatt gttattgttc ttcatgatat caactttgct
    68341 gcaagttatg cagacgaaat tgttgcaatg aaagatggac agttatttac gcaaggaacg
    68401 acccaagaaa tgataaaaaa agatgtattg gatgaattat acgaaatgga catacggatt
    68461 tgtgagattg aaggccgcag attctgtctt tatttctaaa actaacatta ggagagaaga
    68521 gatgaaaaaa ttagtagtag gtatcttgat tctagcatca tttggtttag cagcatgtgg
    68581 aaatagcaac aacaccagtc aggcagacac aaaaaaaagc agcacacaaa ctgaaactac
    68641 attgacgata acagatagta atggagacca aatcgaggtg ccaaataatc cagaaaaagt
    68701 cgtcgtattc gacaatggtt ctttagatac gatggatgct cttggtgttg gagataaggt
    68761 agttggagca gctacaagca gccttcctga gtatctttca tcctataaaa aagtagaatc
    68821 agcaggtgga ataaaagaac cagacttaga aaaaattaat cagcttcagc cagatctaat
    68881 catcatttct ggccgacaaa gagattttca aaaagatcta agtcaaattg ctccgaccat
    68941 tttcctttct ttagatgcga aaaatccatg ggaatctttc cagcaaaatg tcactgcttt
    69001 aggggagatc tttggtaagc aagaagaagc taaaactcaa ttagaggaat tatctagtgc
    69061 aatcgatcag acgaaaaaga aagcagaagc tactgacaaa aaagcactag tcacacttgt
    69121 gaatgaaggg caattatcag cctacggatc tggttctaga ttcggtttca tccatgattt
    69181 atttggcttt gaacaagcag atgatcaaat cgaagcatcc actcacggtc aaagtgtttc
    69241 ttatgaatat gtgctggaaa aaaatccgga tatcttattt gtagtagaca gaacaaaagc
    69301 tattggtgga gacgacagca aagatgatat ttctgccaat gaactggtag cacaaacgaa
    69361 tgctggtaaa aatcagcaga tcatctccct tgaaccagat gtctggtatt taagcggggg
    69421 cggtttagaa tcaatgaaac tgatgatcga agatgtgaat caagcattta aatagcataa
    69481 ataacagagg attaaactct catactatgt aacaataatg tttcttacat tcttaaatag
    69541 caagagccta tcctcaaaga agttatcaaa aaccatccgt aaaatcgtat tgatgatttt
    69601 acggatggtt tttatttatt tgagaaatct tttttcaacg tgaattcatt atctacatca
    69661 tacgggttga ttctagaatg gggagtggca aaaaatagtg tgatccattt tttcagcatc
    69721 aagatcgcct cctttgattt gaatcaaagg tacaaagcga aacttagata aaacttaaat
    69781 ttagatattt ttattttgta ccgatctctt ctttaaacga tgttccatct gctgcttctc
    69841 ggcaataagt ccactagact agaaaatatg agaagctatt ttctgtccag cgttcttatt
    69901 actcaaagca aatcgcagtt gtcacaatct cttctaaacg atgttccatc tgctgcttct
    69961 cggcaataag cccactagac tagaaaatat gagaagctat tttctgtcca gcgttcttat
    70021 tactcaaagc aaatcgcagt tgtcacaatc tcttctaaac aatgttcaat cagctgacct
    70081 tcggtattag ctcaaagcac tgatttcaca acctctattt aggcatgtgt ctcagcaagc
    70141 ggttgatagt tgatgatctg catttttcga taaaaatcgg cgggaagctt actccaccgt
    70201 tttaataatt gatagaaata actctcttct gctttgattt tatactcgct taatatcaat
    70261 ccaaaactat tcgttttttt tgaagctaat tttttataaa tatccaatgc tttggtttta
    70321 tcttcattga caaagagtgt ttttacttca atataagaac cctcgatatt ttgtgtttct
    70381 tcgataaaat agatgttttt tatatattcc ttcatagtga ttcctccaaa gaagtctttt
    70441 atttgataag tttactctac cgaagagttg ttaataatcc gtgaacaaaa agtaattctt
    70501 tttccaatag ttgttaaagg ttttttattt tttatagtat tttttgttat ttaagaaagg
    70561 aataaggtta aacaaataac aggttgcttt ttgggtcttt ttccgttcaa gaaactgaac
    70621 gaagaaaagg gaaagttgtc tcttttgtga taagagaaat cataataaac gaatgactta
    70681 ctttccaata aattgagaac agtcagaacc agacaaatta gttgcatctg atgaataaag
    70741 tgattattct atgacatgag gtgatacaga tgaaattaga agtgacaaaa gaagcacaag
    70801 aagtattgaa gaataaatta gaagcagacg atcaactttt attagatatc gaaaacggtg
    70861 acggtccatt tgcagaaagc caagtcagtt gccaattgga tacggcattt cgattgatca
    70921 ttgtcaaaaa agatacacaa acagatctaa gtctttattc tgtagtggct gatacaccag
    70981 ttggaccaat caaaatcaaa gacagtgcaa tactttacat ggatgatcca tccacacttg
    71041 ctttagaacc aacttataat agtttacaat taaaaggacc aagcggcttg agaaaaggca
    71101 acttgcaagt tgttcgaaaa gactagaggg ataaaatggg aaaattggcg atcatcagcg
    71161 acctacatgt ggacatcaat aaattcggcg aatcagagct gatgcagctt tggcaagttt
    71221 tgcaaaagca caagatcact cggcttcatc tagccggaga tacggctaat aaagtagacc
    71281 gttgcctagc tgttgtcgaa tttttcgtca ataaaggatt atctacgaca tttcatttcg
    71341 gcaatcacga gttggcagat gtgcccaatg aacagatgat ggaccatttt ccagacccac
    71401 attttttaaa tgaacggtat attgctttaa atgagcagac cgttctttta gggatgaatg
    71461 gctggtacga ctatcagttt tccgaattga aagattacga ggcaatcgta cgaatgaagc
    71521 gtttgtattg gtatgatcgg ttcatccagc gtgggaaaac agatctcgag gtcaatgcag
    71581 aaatgcttgc agctgcaaaa aatttgctag accagctgga agcaaaaaaa cttgaggtga
    71641 ttttatccac tcatttcgtt cctaaacggg catttatcat gtatcaatct gctccttatg
    71701 agcgttggaa caaattaaat gcatttttag gatcagaatc attcggagaa ttacttgacc
    71761 gttattcaaa tatcaaacaa gtagtttttg gccatacgca tcgtcgcttt gaagataaat
    71821 ccatcggtca cacgatttac agctgcagac cttttggtta ttattatgaa tggcagctga
    71881 cccgagattt tgtcttgaaa gaacagttgc tagacagcta tgatcctatg aaattacgtg
    71941 tcctcttgcg tgcccatcac ccagcttttc aggcctatca aacacaacat ttgcaagagg
    72001 aatttgaaca agcgatgaca atcgttccgt attgagacag cattagtaat gtgtaaaaga
    72061 aaataccttg taaaacataa ggataagtaa gagcagtaga tccatttatc gtggatatgc
    72121 tgcttttttt gcggaaaata atcagcgaat gtttatttga tcggatgatt tgtaactcgc
    72181 agagtactag atgcaagcgt gtattctttt tttgaacgat aatcacaaaa aaaatataat
    72241 atacattttt tatttaatta taattaatat tgattgaagt ctaggcagtc aagtcacatt
    72301 ttgatagata ggagggggac ttacgaatta ttttaaaggc tatgacagct gtatttctag
    72361 attgtgtttg catcaagttg caataaaaac tagaaatcaa atcgggctga taatcattta
    72421 taactaatcg atacatagga ccaaatatag gtctatgttc ttttatttca taagtatcgt
    72481 aaaacagaat tttgctatgg attaatccaa tcgactgata tgtttagtaa ataaagaaag
    72541 aggaatgtca atgatgaaaa aagaaatcgt attaacagca gcaataatgt tattcagcat
    72601 ggtagcaagt acgacttttg tttctgcaac tgaagtatac ccaaaggaat ataacacaga
    72661 aggaacgatt acatttgaag caggagatga gggtgtaact cctcctgttg atccagagaa
    72721 tcctgatccc aataaacctg tcgatccatc agatcctcca agccctggaa caggaggggc
    72781 attatcgatt gattatggat caaaattcaa atttgggact caaaaaattt ctactgcgga
    72841 taaaacgtat tatgcagctg ctgatgtgat gaacgatggg tctagaaaac cgacatatgt
    72901 ccaagtgaca gataggagaa gtaccttatc tgggtggaaa ttaagtgtct ctcaaccaga
    72961 acagtttaaa actgccagtg gggatgaact agttggagca cagctgaaat ttacgaaagg
    73021 gcaggctgtt tctttggttg atccaacata tacgccgcaa acggtgaatt ctgaattaac
    73081 gttgacaccg ggaggaaaca atacgttagc aattaatgct aaatcaggaa caggtgtggg
    73141 gacttgggtc tatcgatttg gtgcaaatga aaatgaaaat caagatgcgg tacagctttc
    73201 ggtacccggt aaatctgtca agttagcgca acaatattcc actaaattag tttggacatt
    73261 agaagataca cctaacaact agtttactga aaagaactgt taaaaataaa tacgtagtca
    73321 tattgtcttg cgaggtaatc gagcaaaaat tgtcaaaggc taggctaaat ttgtttggat
    73381 acgaatagtt catctaggaa tttaacgatc aggaggaaaa gatatattga aaaagaggag
    73441 gatcgtgctc attttaagca gtctcttagt gactaatatc tttccgatca tagggtactc
    73501 tttggaattg aatcagttgg agcatggaaa tagaagagac gaagaaagca aactcacttc
    73561 gacattcgac agtttaatag aatccaacca gacacaagaa agcagtgagg atttaagtat
    73621 ttcgagtagt ggagagacca ctgacaacgt agaagctgag ggttcggaca aacaaggact
    73681 agaagatgca ccaatttctg cggttgagct gcctgacgat cccaatatta tttctatcga
    73741 taaaattttt caaacaccta tcggtactag cacgtccata ttggaaaatg ggaagttact
    73801 gcagttgaac ccagcagaaa ggtctcaaag aggagctatt tggtcaaata agaagattag
    73861 tttactctcg gattttacat ttaaatctta tttatactta ggaaatcaac gagatagagc
    73921 gggagatggc atgaccttta cattgactgg cgatcctaga atggctagta atcccagtca
    73981 agttattgga tcgccaggta tgggaattgg ctcatattct actcgttctg gccaacctta
    74041 cattgcgaat gcgctctcga ttgagtttga tacgtataaa aatagtggtt cttctgatcg
    74101 aatggatcga gagataactg ctgataatag agggcatgga catgtcgctt ttgtcacgcc
    74161 taaaccaaat aataataatt attctggaga gcatactggc gtgacggtag ctcctacatt
    74221 tctttctaat ggcacatggc gcttgttaat aattaaatgg gacgcggagc aaagaagtct
    74281 tacttatgat ttggaaggtg tcggtcgctc ttctcggatt atacctgatc tcattaggca
    74341 gtttggttct acagaagtaa attgggggtt tacttcttca acaggtactt tttttcaaga
    74401 aaatgctgtc gctgtcacgc gacttccatc gaatgtcaca tcaacagctg atgtaaaagt
    74461 caacgatagt gattatgggg ccatcgctga agctggagga aacgataaga taactatcag
    74521 aaatacattg aaggtcgagg gggattttct tgaatataag aaaatgcaga ctagtatcga
    74581 cctcccacaa gaattaacta ttcccgagca tatcttgatc aatggaaatc aaattgatgc
    74641 caaagatatc ttgataaccg gaaatcgagt cacgctaaat ctgacagatt attttattgc
    74701 tggagatacg ttaataatcg aattggagac aactttgcag gaagtaattc ctgaaaaagt
    74761 actcactatg cattttgaat accttgaaaa cgggaatttg attgagcaat cgaatgaaat
    74821 aaacctaaag atcgcaaagc tgaaggagat agatatccat gtttattata aagataaaga
    74881 cagtcagatt gatattgctg aaatgaaaac aatcactggg aaaataggag agaagtataa
    74941 agaaactcct attgatattg aagggtatgt ttttgactcg gattcagcga atacagaagg
    75001 catcttctcc gaaaatacag aggatatcta tttttattac agaaaaggca aactttatct
    75061 ctcaactgct cctcaatatg tcaattttgg aaaacataaa atatccagta gaccattaag
    75121 tgaattcgga cagttttcag gtgggttgaa aattatagat gaacgggctt ttggaagttg
    75181 gaaattacaa ttgaaacaag agaaagttct tacaaatgga gattttgagc ttccagaagc
    75241 tctttccttt gttacctctg aaaatacaac ggttataggg acatccgctg ttacgatttt
    75301 cgaaagtgat caaaagggtg aaagcgattt gtcctctctt ttagattcta cagctcatcg
    75361 tggaatcaga atagatattc ctgtagaaaa ccaaagaatc ggaacctttg aggggaaact
    75421 atcttggata cttgcagatg tcccaggaaa ttaacaggaa gagaagaata taacaaaatt
    75481 attgagtttc aagaagggca caggtaccat aggctcttgt gtcccacaga gacaagattt
    75541 tgttatagtc ttctcttaca tatgattaaa ggagcgattt tcttgagacc aaaacaacaa
    75601 ttatttataa cactcctagt tattttaggg gcacttttta acaatatatc agtgtcagct
    75661 agtgcattta atttttcagt gacgccgata acttcagaga atcaaatcga caagagaaaa
    75721 acttacttcg atcttcaact tgatccggat caggaagtag aagtaaaagc ggaattgaga
    75781 aatgatacag aaaaagaagt gaaaatcgat atttctgtga atagcgcaac caccaattca
    75841 aatgtgatgg ttgaatacgg aaaaaacgag attgaaaaag acatgagcct gatctttgat
    75901 ctggtagatt atgtgagcta tccacagata gtgacgctaa aacctaaaag tgtccaaacc
    75961 gttgcttttc atgtcaggat gccgaatgag cgatttgatg gtgtattggc tggtgggatc
    76021 acattccaag aaatccagac ggaaaaggac caaacagaaa ctaaggatca aagcttatcg
    76081 attgagaatg aatacaccta tattattgct ttgttgatgc aacagacact gaacgaagtt
    76141 gctccgaacc ttactcttca tgaagttaaa ccagatcaaa tcaatgcaag aaatgtcatc
    76201 ttagcaaacg ttcaaaatga tcaaaaaacc tatatcaatc aagtagttat tgaaacaaaa
    76261 attacaaaaa aaggacattc tgaagtttta tatcaagagg aaaaagaagg attgcagatt
    76321 gcgccgaata caaatttttc ttttccaact gctttaaatg gtcaaccgct aaccccaggt
    76381 gaatatcacc ttacaatgac tgttttagga aatgaaaatg aaaatggaaa attttcgaga
    76441 aaaaaaggaa atactacgat caactatacc aatcaatggg tatttgaaaa agattttaca
    76501 atagacggaa aagtagccaa ggaattgaac acgacggatg ttacgattaa aaaagacaat
    76561 aattggattt atatcttagt agcttcactt ttcttattgt ttattttatt atgcatactt
    76621 ttgtttgttt tgagaaaaaa agaagagaaa gaaaagtaag gttaagataa caaatagtaa
    76681 atttttatta ttgtaggatg gttgggctct ttttataaca atataaaata taccatttta
    76741 ttaataaaaa tgcatactag taaatgatat aattctaata acaggtttga tcgcgagaaa
    76801 ggccaaataa aacgctctcc aaaatgttaa aaaaaagaca ggacgatgta tattatacaa
    76861 acaagaatcg ctgacaacag tgactcggat ccaggaaatc agttttatcc ccagctagtt
    76921 ggtgaatgca tggaaagtaa tatacgtaga aagagctgat gactaatgaa ttatgagttt
    76981 tttttaagca aagaagatca cagaagttat tcattactta aatatttaga agcaagctca
    77041 aatttatcag agtcaatatc gaatgttcaa gaagagttgt cgctatcgac atttctcttg
    77101 aaaaaaacga tcgataagct gaaacatgat ttacaaaagt tcgatctaga gaaaaatttg
    77161 cgagtaaccg tcagtgaatt ggatatatgt ctggaaatta atggaaaatg ttctagcaaa
    77221 gctctgttat ctcgttatat aacggattct ttatctatga aaatggtatt ggctttcttt
    77281 caggaaaaat atatctcagt agaaaatttt gctaaacagc atcacgtgag ttattctgtg
    77341 gcttataaag tattacaaag actaaaaaga aatctaaaaa aatatcaaat tttttttgaa
    77401 aagagaaagt tga
//
LOCUS       DAZULR010000006        76543 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.006, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000006 DAZULR010000000
VERSION     DAZULR010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 76543)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 76543)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..76543
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.006"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..420
                     /locus_tag="ACG8ZV_000426"
     CDS             <1..420
                     /locus_tag="ACG8ZV_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HFS4995796.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(504..1226)
                     /locus_tag="ACG8ZV_000427"
     CDS             complement(504..1226)
                     /locus_tag="ACG8ZV_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HFS4995797.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(1216..1953)
                     /locus_tag="ACG8ZV_000428"
     CDS             complement(1216..1953)
                     /locus_tag="ACG8ZV_000428"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4995798.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            complement(1965..2957)
                     /locus_tag="ACG8ZV_000429"
     CDS             complement(1965..2957)
                     /locus_tag="ACG8ZV_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFS4995799.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            complement(2972..3715)
                     /locus_tag="ACG8ZV_000430"
     CDS             complement(2972..3715)
                     /locus_tag="ACG8ZV_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4995800.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     regulatory      complement(3789..3893)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(3956..5278)
                     /locus_tag="ACG8ZV_000431"
     CDS             complement(3956..5278)
                     /locus_tag="ACG8ZV_000431"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFS4995801.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     gene            complement(5265..6230)
                     /locus_tag="ACG8ZV_000432"
     CDS             complement(5265..6230)
                     /locus_tag="ACG8ZV_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4995802.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            complement(6227..7765)
                     /locus_tag="ACG8ZV_000433"
     CDS             complement(6227..7765)
                     /locus_tag="ACG8ZV_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HFS4995803.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            complement(8181..8468)
                     /locus_tag="ACG8ZV_000434"
     CDS             complement(8181..8468)
                     /locus_tag="ACG8ZV_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995804.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            8602..9270
                     /locus_tag="ACG8ZV_000435"
     CDS             8602..9270
                     /locus_tag="ACG8ZV_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFS4995805.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            complement(9561..10301)
                     /locus_tag="ACG8ZV_000436"
     CDS             complement(9561..10301)
                     /locus_tag="ACG8ZV_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995806.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(10431..11378)
                     /locus_tag="ACG8ZV_000437"
     CDS             complement(10431..11378)
                     /locus_tag="ACG8ZV_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFS4995807.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            complement(11507..12271)
                     /locus_tag="ACG8ZV_000438"
     CDS             complement(11507..12271)
                     /locus_tag="ACG8ZV_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFS4995808.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            complement(12275..12664)
                     /locus_tag="ACG8ZV_000439"
     CDS             complement(12275..12664)
                     /locus_tag="ACG8ZV_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995809.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            12799..13341
                     /locus_tag="ACG8ZV_000440"
     CDS             12799..13341
                     /locus_tag="ACG8ZV_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HFS4995810.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            13489..14121
                     /locus_tag="ACG8ZV_000441"
     CDS             13489..14121
                     /locus_tag="ACG8ZV_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995811.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(14255..14380)
                     /locus_tag="ACG8ZV_000442"
     CDS             complement(14255..14380)
                     /locus_tag="ACG8ZV_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HFS4995812.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(14514..15407)
                     /locus_tag="ACG8ZV_000443"
     CDS             complement(14514..15407)
                     /locus_tag="ACG8ZV_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HFS4995813.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(15589..16515)
                     /locus_tag="ACG8ZV_000444"
     CDS             complement(15589..16515)
                     /locus_tag="ACG8ZV_000444"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HFS4995814.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(16600..17361)
                     /gene="pflA"
                     /locus_tag="ACG8ZV_000445"
     CDS             complement(16600..17361)
                     /gene="pflA"
                     /locus_tag="ACG8ZV_000445"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HFS4995815.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(17605..19836)
                     /gene="pflB"
                     /locus_tag="ACG8ZV_000446"
     CDS             complement(17605..19836)
                     /gene="pflB"
                     /locus_tag="ACG8ZV_000446"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HFS4995816.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(20113..22563)
                     /gene="parC"
                     /locus_tag="ACG8ZV_000447"
     CDS             complement(20113..22563)
                     /gene="parC"
                     /locus_tag="ACG8ZV_000447"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HFS4995817.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(22575..24620)
                     /gene="parE"
                     /locus_tag="ACG8ZV_000448"
     CDS             complement(22575..24620)
                     /gene="parE"
                     /locus_tag="ACG8ZV_000448"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HFS4995818.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(24786..25220)
                     /locus_tag="ACG8ZV_000449"
     CDS             complement(24786..25220)
                     /locus_tag="ACG8ZV_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HFS4995819.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            25347..25985
                     /gene="plsY"
                     /locus_tag="ACG8ZV_000450"
     CDS             25347..25985
                     /gene="plsY"
                     /locus_tag="ACG8ZV_000450"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HFS4995820.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(26117..26992)
                     /locus_tag="ACG8ZV_000451"
     CDS             complement(26117..26992)
                     /locus_tag="ACG8ZV_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HFS4995821.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(27074..27865)
                     /gene="codY"
                     /locus_tag="ACG8ZV_000452"
     CDS             complement(27074..27865)
                     /gene="codY"
                     /locus_tag="ACG8ZV_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HFS4995822.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(27883..29283)
                     /gene="hslU"
                     /locus_tag="ACG8ZV_000453"
     CDS             complement(27883..29283)
                     /gene="hslU"
                     /locus_tag="ACG8ZV_000453"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HFS4995823.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(29297..29845)
                     /gene="hslV"
                     /locus_tag="ACG8ZV_000454"
     CDS             complement(29297..29845)
                     /gene="hslV"
                     /locus_tag="ACG8ZV_000454"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0004298 - threonine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HslVU peptidase proteolytic subunit"
                     /protein_id="HFS4995824.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(29882..30787)
                     /gene="xerC"
                     /locus_tag="ACG8ZV_000455"
     CDS             complement(29882..30787)
                     /gene="xerC"
                     /locus_tag="ACG8ZV_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HFS4995825.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(30985..32361)
                     /gene="trmFO"
                     /locus_tag="ACG8ZV_000456"
     CDS             complement(30985..32361)
                     /gene="trmFO"
                     /locus_tag="ACG8ZV_000456"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0047151 - tRNA
                     (uracil(54)-C5)-methyltransferase activity,
                     5,10-methylenetetrahydrofolate-dependent [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HFS4995826.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(32330..34408)
                     /gene="topA"
                     /locus_tag="ACG8ZV_000457"
     CDS             complement(32330..34408)
                     /gene="topA"
                     /locus_tag="ACG8ZV_000457"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HFS4995827.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(34530..35387)
                     /gene="dprA"
                     /locus_tag="ACG8ZV_000458"
     CDS             complement(34530..35387)
                     /gene="dprA"
                     /locus_tag="ACG8ZV_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HFS4995828.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(35443..36210)
                     /locus_tag="ACG8ZV_000459"
     CDS             complement(35443..36210)
                     /locus_tag="ACG8ZV_000459"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HFS4995829.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDVRSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(36203..37063)
                     /gene="ylqF"
                     /locus_tag="ACG8ZV_000460"
     CDS             complement(36203..37063)
                     /gene="ylqF"
                     /locus_tag="ACG8ZV_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HFS4995830.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            37323..37721
                     /locus_tag="ACG8ZV_000461"
     CDS             37323..37721
                     /locus_tag="ACG8ZV_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFS4995831.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            37958..38500
                     /locus_tag="ACG8ZV_000462"
     CDS             37958..38500
                     /locus_tag="ACG8ZV_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HFS4995832.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(38583..39134)
                     /gene="lepB"
                     /locus_tag="ACG8ZV_000463"
     CDS             complement(38583..39134)
                     /gene="lepB"
                     /locus_tag="ACG8ZV_000463"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFS4995833.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(39286..39513)
                     /locus_tag="ACG8ZV_000464"
     CDS             complement(39286..39513)
                     /locus_tag="ACG8ZV_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HFS4995834.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            complement(39510..40028)
                     /gene="msrA"
                     /locus_tag="ACG8ZV_000465"
     CDS             complement(39510..40028)
                     /gene="msrA"
                     /locus_tag="ACG8ZV_000465"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFS4995835.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            complement(40048..40761)
                     /locus_tag="ACG8ZV_000466"
     CDS             complement(40048..40761)
                     /locus_tag="ACG8ZV_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HFS4995836.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            complement(40764..41660)
                     /locus_tag="ACG8ZV_000467"
     CDS             complement(40764..41660)
                     /locus_tag="ACG8ZV_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFS4995837.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            complement(41818..42660)
                     /locus_tag="ACG8ZV_000468"
     CDS             complement(41818..42660)
                     /locus_tag="ACG8ZV_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFS4995838.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            42792..43445
                     /locus_tag="ACG8ZV_000469"
     CDS             42792..43445
                     /locus_tag="ACG8ZV_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HFS4995839.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            complement(43508..44035)
                     /locus_tag="ACG8ZV_000470"
     CDS             complement(43508..44035)
                     /locus_tag="ACG8ZV_000470"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HFS4995840.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(44055..45002)
                     /locus_tag="ACG8ZV_000471"
     CDS             complement(44055..45002)
                     /locus_tag="ACG8ZV_000471"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004799 - thymidylate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006231 - dTMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HFS4995841.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            complement(45014..46897)
                     /locus_tag="ACG8ZV_000472"
     CDS             complement(45014..46897)
                     /locus_tag="ACG8ZV_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFS4995842.1"
                     /translation="MKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKTS
                     LLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVRA
                     YEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIST
                     LSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDRY
                     FLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMRA
                     GVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRINDQ
                     TLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQE
                     NEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEKR
                     RLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVAD
                     KLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKEW
                     ETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSEW
                     VED"
     gene            complement(47060..49138)
                     /locus_tag="ACG8ZV_000473"
     CDS             complement(47060..49138)
                     /locus_tag="ACG8ZV_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFS4995843.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            complement(49151..49426)
                     /locus_tag="ACG8ZV_000474"
     CDS             complement(49151..49426)
                     /locus_tag="ACG8ZV_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995844.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            complement(49788..50243)
                     /locus_tag="ACG8ZV_000475"
     CDS             complement(49788..50243)
                     /locus_tag="ACG8ZV_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995845.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(50397..51605)
                     /locus_tag="ACG8ZV_000476"
     CDS             complement(50397..51605)
                     /locus_tag="ACG8ZV_000476"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HFS4995846.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLVEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(51717..52049)
                     /locus_tag="ACG8ZV_000477"
     CDS             complement(51717..52049)
                     /locus_tag="ACG8ZV_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HFS4995847.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            52197..53072
                     /locus_tag="ACG8ZV_000478"
     CDS             52197..53072
                     /locus_tag="ACG8ZV_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFS4995848.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(53154..53735)
                     /locus_tag="ACG8ZV_000479"
     CDS             complement(53154..53735)
                     /locus_tag="ACG8ZV_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ReoY family proteolytic degradation factor"
                     /protein_id="HFS4995849.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(53741..55000)
                     /locus_tag="ACG8ZV_000480"
     CDS             complement(53741..55000)
                     /locus_tag="ACG8ZV_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFS4995850.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(55002..56048)
                     /locus_tag="ACG8ZV_000481"
     CDS             complement(55002..56048)
                     /locus_tag="ACG8ZV_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995851.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(56283..56558)
                     /locus_tag="ACG8ZV_000482"
     CDS             complement(56283..56558)
                     /locus_tag="ACG8ZV_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HFS4995852.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(56801..58111)
                     /gene="der"
                     /locus_tag="ACG8ZV_000483"
     CDS             complement(56801..58111)
                     /gene="der"
                     /locus_tag="ACG8ZV_000483"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HFS4995853.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(58293..59522)
                     /gene="rpsA"
                     /locus_tag="ACG8ZV_000484"
     CDS             complement(58293..59522)
                     /gene="rpsA"
                     /locus_tag="ACG8ZV_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HFS4995854.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(59657..60337)
                     /gene="cmk"
                     /locus_tag="ACG8ZV_000485"
     CDS             complement(59657..60337)
                     /gene="cmk"
                     /locus_tag="ACG8ZV_000485"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HFS4995855.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(60386..61021)
                     /locus_tag="ACG8ZV_000486"
     CDS             complement(60386..61021)
                     /locus_tag="ACG8ZV_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1386/EF1546 family surface-associated
                     protein"
                     /protein_id="HFS4995856.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(61087..62490)
                     /locus_tag="ACG8ZV_000487"
     CDS             complement(61087..62490)
                     /locus_tag="ACG8ZV_000487"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0043138 - 3'-5' DNA helicase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HFS4995857.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            complement(62477..63508)
                     /locus_tag="ACG8ZV_000488"
     CDS             complement(62477..63508)
                     /locus_tag="ACG8ZV_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4995858.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            63539..63760
                     /locus_tag="ACG8ZV_000489"
     CDS             63539..63760
                     /locus_tag="ACG8ZV_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HFS4995859.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(63925..64662)
                     /locus_tag="ACG8ZV_000490"
     CDS             complement(63925..64662)
                     /locus_tag="ACG8ZV_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HFS4995860.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(64815..66155)
                     /locus_tag="ACG8ZV_000491"
     CDS             complement(64815..66155)
                     /locus_tag="ACG8ZV_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFS4995861.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(66392..67915)
                     /locus_tag="ACG8ZV_000492"
     CDS             complement(66392..67915)
                     /locus_tag="ACG8ZV_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HFS4995862.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(68293..68904)
                     /locus_tag="ACG8ZV_000493"
     CDS             complement(68293..68904)
                     /locus_tag="ACG8ZV_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFS4995863.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(69027..69152)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(69234..69950)
                     /locus_tag="ACG8ZV_000494"
     CDS             complement(69234..69950)
                     /locus_tag="ACG8ZV_000494"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFS4995864.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(69956..70525)
                     /gene="scpB"
                     /locus_tag="ACG8ZV_000495"
     CDS             complement(69956..70525)
                     /gene="scpB"
                     /locus_tag="ACG8ZV_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HFS4995865.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(70509..71279)
                     /locus_tag="ACG8ZV_000496"
     CDS             complement(70509..71279)
                     /locus_tag="ACG8ZV_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HFS4995866.1"
                     /translation="MNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDIPIATITEQY
                     MNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEEDPREELVTQ
                     LLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKKIDLIRAMQK
                     ILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESPSKSEVVTTF
                     MALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(71276..71647)
                     /locus_tag="ACG8ZV_000497"
     CDS             complement(71276..71647)
                     /locus_tag="ACG8ZV_000497"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4995867.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(71666..72553)
                     /gene="xerD"
                     /locus_tag="ACG8ZV_000498"
     CDS             complement(71666..72553)
                     /gene="xerD"
                     /locus_tag="ACG8ZV_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HFS4995868.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            complement(72649..73122)
                     /locus_tag="ACG8ZV_000499"
     CDS             complement(72649..73122)
                     /locus_tag="ACG8ZV_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFS4995869.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(73227..74090)
                     /locus_tag="ACG8ZV_000500"
     CDS             complement(73227..74090)
                     /locus_tag="ACG8ZV_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor B family protein"
                     /protein_id="HFS4995870.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYGFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(74286..76385)
                     /locus_tag="ACG8ZV_000501"
     CDS             complement(74286..76385)
                     /locus_tag="ACG8ZV_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division site-positioning protein MapZ
                     family protein"
                     /protein_id="HFS4995871.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
BASE COUNT        20972 a        16108 c        13046 g        26417 t
ORIGIN      
        1 tactcaggac aacaattaac aatcccaaca gaaggctctg cacaagcagc tgctgaacct
       61 caagcagccg ttcaagaagc accagtccaa gctgaacaac ctgttgtaca agaaacggtt
      121 caaacggaaa aacaagcagc gcctgttgct gaaacacaac ctgctcctgc tgtaacagaa
      181 actgctgcta ctccagcaag cacaagctct gcaaaagaat ggatcgcaca aaaagaatca
      241 agcggttctt acacagcaac gaacggacgt tacatcggac gttaccaatt agattcttct
      301 tacttaaatg gtgactactc tgctgcaaac caagaaagag tagcagaaca atatgttact
      361 tcacgttatg gttcttggga agcggcgaaa gcattctggg aagcaaacgg ttggtactaa
      421 gattcattta ttaatcaaac agtttacttt tatacaaaga aagccaaaaa gaggtgcgac
      481 actagttgtg tcacatctct tttttattta cctaatctaa tgaaacgttc caagttttga
      541 taagtatttt ttttaacttc ttcaactgat agctctttga tctcagcgat tgtctttaac
      601 tgttcttcaa gcagtgagac ataatctttt tctgaaaaaa tcccccctaa agcccactct
      661 gctgcatgta gtccatccgt ttcaataagt aagtggtcga ttgggactgc tttagctagt
      721 tgccagactg ctggattctt tttcaaatca agaccaatgc tgaaataaca gcctaaatca
      781 atatagtctt gttgatagtc caaagaagaa taccaatgga tcaaatagtg attagggtaa
      841 gcttggatat aatttaagat ctctttttcg catccttttg tgtgcagtac aacaggtttc
      901 tcatttatgg ctgcaaaagc aagctgtcgc tcaaatactt ttttttgtgt agtcatcggt
      961 acattcgtcc aaatattatc taaccctatt tcaccgatga tccttgcttt tttcaaaaaa
     1021 ggctcaactt gttcaaacgt atagctatct gctttccaag gatggatacc gtaacttaag
     1081 gcttgagtct tacttgctgc aagctgtctg ttttccttcc attcttctgg cgaatcacaa
     1141 ttgatgatcg tcaaaatcgt gtgttcctgc tgaaggagtg ctaaactctg actcccatct
     1201 aaatgacaat gagcatcact taacatctaa ttcacctgcc aataactgat aaatcgtttg
     1261 cttcaactct gattgctgca gtagccattc acgtgaccgt cgtttttcag gcacttgaat
     1321 ctcagcaatc acatgtgccg gacgggcgga aagcacaaga atcctgtctg ataaataaat
     1381 tgcttcttcg atatcatgcg tcacaagtaa agtagtccgc tttgcttttt taggcagctt
     1441 caacatccag tcttgcatct gccctctggt catagcatct aacgctccaa atggttcatc
     1501 aagaagcaag taagaagaag gattcatgat tgttcgtaac aaggccgttc gctgcttcat
     1561 cccgccagat aattgttccg gcaaaaaatg ttcatagccg tttaacccaa agatatccag
     1621 ataatccctt acttgttctt cattgattgt tagatgattg attttttgat ataacgtaac
     1681 gttttgatag acgctcagcc aaggaagtaa catatcttct tgcggcatat aactaaatgc
     1741 tgtatggaga ccagttactt tttgatcgtc tactttgatc gttccagaag tcataggctg
     1801 gactcctgtt aaagttttca gcaatgttga cttaccggct ccgcttggcg cgacaatcga
     1861 tgtaaaggta tctttaggga tagtgaaatg gatgtcttct aatattttca ggttttcaat
     1921 gactacattc aagtggctga tttggattga catatctatc actcctattt tataaactga
     1981 ttagtgaata gttcttgcga aggtacatct tgcttgatca atccgttttc ctgcataaaa
     2041 gctgtataat tgcgccaaac tttttcttcc atcaatcccc aattctcagg atcatccgta
     2101 taattttttg acaagaatgc ttgtgattct tctaaaaacg tccgatcatt ttcttttgca
     2161 tatttttgca acagtttagc actgtcattt ggatccttaa tagcttcctg atagcctttt
     2221 ttcgtggcat ccataaaaga ctgtaccaat tctggatcac ttttgatcag ttgatcattc
     2281 gtaataatta ccggagtata gtaatctaac cgttcatcta attctttcaa tgggatatag
     2341 tttagttcaa tacccgcttc ttttgctttg atcatatccc aaccttcaaa gtaccattgg
     2401 atatctgagg attttcctaa gctttctggc ccttctccat tgcttcctac cattgtcagt
     2461 tttgaaaagt ccccgccgtc tttttccatc acagctttta agacagcttc ttcacttgga
     2521 ctttgccaac ctgcatatgt ttttccttca aaatcttttg gtgaatggat gttactgtct
     2581 gatagggtgg cgaatccaga agtattatgt ttgatcactg tagcaattgc tttgactggt
     2641 atattctgtc catctgcgtg agcataagtg acatcttctt gataacttac accaaattgt
     2701 gctttgtccg cacctactag accaatactt gtcgaattat ctcctggttc gatgatttgg
     2761 acatttaaac cagcctcttt ataatagcct ttttcttttg ctaggtagat gccagtatga
     2821 ttagtattcg gtacataatc caaaacaagt gtcacttttt tcaaatcctt tatttcttgt
     2881 ttgctacttg tttcttttgc agtgccacaa gcggataaaa gcaacagtag cggtaataaa
     2941 agccataatt ttttcatttg atccccttct cttaaaaaat ataaagcata cgataatacc
     3001 cttttttcaa taatgaacaa gcgccattca gcaataaact caatagaatg acacaaatga
     3061 tcgcagcaaa aactttatcg atctggtagc tgttttttac gcgtatcatg taatacccta
     3121 agcctgcttg agcgcttagc cattctccaa cgactgctcc gctgacacaa taagtagcag
     3181 ccacttttaa accggaaaag aagccggata aacccgctgg tattttatat attcgataaa
     3241 tcttccctgt atctgccccc atcgttttca aaaagatgat ttgctctttt gatactttcc
     3301 tcaatgtatc cgaaaaagaa actacgatcg gaaaatagct tatcaagaca acaaggatca
     3361 cttttggaag cataccgaaa ccaaaccata gggtaagtaa tggccctaac accatgattg
     3421 gcaacatttg tgaaatcact agtaacggat aaaaagacat ttctaaaaac ttccaataat
     3481 ccattgccaa ggcagtaata aaagaaagaa cgctagctat taccaaacca agcactgctt
     3541 catttaatgt cgtgacagaa tgggaaagta atacttgtgc atctgccgct aatgcagaaa
     3601 atacagcagc aggtccgggt aaaataaagg caggtatttt ccaaactatg acaacaatct
     3661 gccaaataat taaaatgaat gccatactga ctgctggata aagatttttc ttcattttgt
     3721 tacctccttt cttctaatat gaataacaaa aaacgcttga aatgggcacg acatagtaac
     3781 ccgcttcaag cgtctgctat gtttctccct tcaccagtat taactgacag gttcaatggg
     3841 tctaagttca caacttactc tcatgtcgtc tacgacatcc ccagaaacag gtattcattt
     3901 tttaaagtgt agcacaagaa ggaaaaagca acaagcgctt tagttatcat gctgattatt
     3961 tcaataaata ggagagatca cttgccaatg tcggataccc catgatatag ctatccaact
     4021 cttttttagt caatttttga ttgatgacga gtgtcaaatc atcgatcaat tcgtctgctt
     4081 gctcgctaat cactgcagca ccaatcaaat aattttgctg gtcaaaggtc aattcagcct
     4141 tagcaactgg ttcattgaca cgatgatagg tgaaccaact ggtaagatcc atctctacca
     4201 cttgatctga cgaagaggcg tgactttttg taactcctac ttcagcaagt ttaggactgg
     4261 cgtagacgat cgtaggtata atcggatatt tgataggttc gcttgttgca tccgttatcc
     4321 gcttagctac ataatttcct tcaaaagtgg cgactggtgt caattttggg gttttccttg
     4381 aaacaatatc tccacacgca aaaatttttg gattgctcgt ttgcagataa tcattgactg
     4441 caattccgtg tttatcaaag acgatattcg cttgctcaag tgctaaagat tctgtattcg
     4501 gctgtctccc agtcgcacaa aaaatcatat ctgctactaa ttccgtctct tttccgacta
     4561 aacgatagcg agtaccttct gaaatgatct tttgggtttc aacaccaaaa gcaaactgaa
     4621 tgccagatgc ttccatttga tggacggctt cctctaccaa agacgcctca aattctttta
     4681 atggccgttg attatgatgg acaatggtta ctttgctccc tgcagcattg gcaatcgtag
     4741 ctagctcaaa agcaatataa ccaccaccga taaaaatgat ttctttaggc agtacaggca
     4801 atgataaaaa gtctgcacta gttttcaagt attcctttcc ctccactggt aagatcgtag
     4861 gtctttgccc ggttgccaaa actaagtaat ccgcatggaa gacttcttcg ttgacttcaa
     4921 tagatgaatc atccaaaaaa cgagcggttc ctgaaagatg atcgatttca gcttctgcta
     4981 attgtttttt tcggctttct gggactggat ccgtaaatgt tcgtttgaat ttttgaagtt
     5041 cttcccagtt ggcagttggg atctcgttaa aaccttttcc actcaattgt tttacccgat
     5101 tacgtgcctc tactgcactt aacaagactt ttttaggatc acatccacgg ttaggacaag
     5161 tcccgcccca tagatcttct tcgaccacta gtactgtttt acctgcttct ttcaatccat
     5221 aagcagcact taagccgctc acacctgaac cgatgatgat tgcatcatat gttttcattt
     5281 ccttcctcct ctcgacttaa aaaagcaaag atttctttac ttgtcagcga cccaatactt
     5341 ctttgctttt ctactatcac aatgcttgga tacaccgaaa gaagcgaata tacttctttc
     5401 ataggcgtat caaagcaaac ttgttgacga gcattttctg gtatttcatt taagaaatat
     5461 ccattgacga ctaaatcttc tactcgccac tctttcgtct gtttcggttc atcaaagaaa
     5521 tgccgaacgt agtcgttttt aggattcatc aataactgct ctggtgtgtc acattggata
     5581 atttctccat ccttcataaa tgcaatacga tcacctagct tgattgcttc ttccatattg
     5641 tgcgtaacga aaacgatggt cgtgcccaat tcttcgtgta aggacaaaac caattcttgt
     5701 aatgagtttc ttgaaatcgg atctaatgcg ctaaatggct cgtccatcaa aatcacatct
     5761 gggcttgcag caatagctcg gatgatcccg atccgttgct gttctcctcc agacaactct
     5821 ctaggcatac gatctcgata aatatcagga gataagccaa ctttttgaag aagttcatct
     5881 acacggtctg ctcttttctg cttttcccaa cctaacattt cagggatgac ttcaatattt
     5941 tgcttgactg tcatggtcgg gaacaaagcg atttgctgca gcacatatcc catattccac
     6001 cgcattttct gcagattata ttcatttaac gattttcctt tgaagtagat gtctcctgct
     6061 gatggtttag ataatccatt gatcattttc aaagtagttg tttttccact accggaagga
     6121 ccaaccaaaa caaagatttc tccttttttg attgccagat ttaggtcatc gatgacatac
     6181 tttccatcat actttttttg cacatgtttg aactcgatta atttagtcac tgatcttcct
     6241 cctttactaa tccttcattt ttcaggaaga ttcgtgctac ttctgtcggc tttttctttt
     6301 cgacattgac ttggtaattc atatcaatca tttgatcctc tgttattttt ccgcttaatt
     6361 tattcagtgc tttaacgatt tcaggatgtt ctttagcaaa atcttttttc atcagcggtg
     6421 cgccttgata agctgggaat aaccctcgat catcttctag agtcactaga tcgtactcct
     6481 tgagctggct atctgtggaa taggcatcca caatattgac atctccatta ttgattgctt
     6541 ggtaacgcaa acttggctcc atgctttgta cacttgaaaa attcaagcca tatgcttctt
     6601 ggattccttt atatccatct gaacgatcaa taaattccag tgtgaatccc gctttgatct
     6661 gatcagagat agctgccaaa tcggaaatct ttttaagttg atgttcgttc gcaaaagatc
     6721 tcttgactgc caaggcatac gtattttggt aagccattgg ttttaataat gtcatatcga
     6781 attgcttatt caataattct tctgcttcgt catatgtttt ttcttttgtc aaatcagcac
     6841 ttttcattgc ttcaggtacc ttcaccaagc tttctaggac agtacctgtg aactcaggat
     6901 agatatcgat ttgaccttga tccagtgcat tgaacaaaaa actcgtcttg ccaaaattcg
     6961 gttttaattc aacttctgtt tttgtgttgt cttcaatcaa ttctttatac atttggatca
     7021 ggatttcagg ttccgctcct aattttccag caatcgtgat ggtttcattt ttaaacaagg
     7081 cagactgata taaagaaacg ccgccaaata aacacaccac tgctgctaaa gtaatgatgg
     7141 aatatcgagg tttcttatgc tgcaaccagc gaatcagtcc gctgaatata attgcaagca
     7201 aggcagaact gatcgcacca atcaatgtca aaacaggtgt atttcggtca atacctaaca
     7261 aaataaatgt ccctaatcca cctgctccga tcaatgctgc caaagtagcc gtaccgatga
     7321 ttaaaactaa ggcagttcgg atacctgaga taatgacagg taatgcgatg ggaagctcta
     7381 ctttcagcaa gcgtctcatt ctggacatac caaatgctac cgctgcttct tcaatagacg
     7441 ggtcaatttc agctagacca atatacgtgt tttggaaaat cggaagcaaa gcgtaaataa
     7501 caagtgcaat caatgctgga acagttccga tccctacaaa tgggataagt aaacctaata
     7561 aggcaagtga aggaatcgtt tggagcacac ccgtgatctg caataagact tctgccattt
     7621 ttttatgatt ggctgcccaa atcgctaaag gaatagcaat cagtgctgca atcagcaaag
     7681 aaatgagaga aatggacaga tgttgaaatg cagcttccag caactcgcct tttctttcac
     7741 ttaatgtttg tataaaatta ttcatgcgac cttcctttct gttattcttt aagtataaac
     7801 atttctttcc tttttcccaa ctaacttgtc ttgccttaac cttacagcac gaacaaaaaa
     7861 aagaaaaaaa tacctctaaa tatgctgaca aaaaaagaat ccaagcaaca aagtcggatc
     7921 aactttttgg ttctcgtttt ttcactacga ataccataaa aatctatacg aaattgtcac
     7981 ttggaatcag ctatatcttt tttacacaca caacttttat tttaataaaa agaaacagcc
     8041 aataaagtag aaatctcgtg ggggagaaca cctttattgg cctgttcaac gaatattata
     8101 ctgtatcatg acactttttt gccaaaaatg taaaaaatgg ttgttttgac atcataaacg
     8161 tcttgttttc ttatttttac ttatatcacc actttatttt ctatctcttt cactccataa
     8221 agaggaatga gttcttcttt tgactgataa taaacagctt tctcacggtt cttcatcaaa
     8281 aaaagaaaga tgtctttcat agcaagtggt gctttgccgt gttcaaataa aaagataaat
     8341 tgatttgctt tatttatctg gaccattgtc acaggcacca gtttttgttc ttgagccaaa
     8401 aaaactcctt gatactctgt ttttttgggt gattttgtaa gaattgtcaa taagtctgct
     8461 gctcgcattt ttccactcct tatttgataa ataaaaagaa acagccaaaa ataatttttt
     8521 ttcattttcc tcttgaagta agagtataag tcagtataat aaagaagttg ctgaaaattt
     8581 tcaaaagaaa agaggctaga aatgaaaaaa ttaaatttat ttacagaatt gtgcggaatc
     8641 attttaggcg caggaatcta cggattagct gtgacaggaa tcaatattcc atctaagctg
     8701 gcagatggtg gggttactgg tattgctttg cttttgcata atctttttgg attcgctcct
     8761 tctgtcactt cactgctttt taatttacct ttattgctta tctcattgtt tctttttgga
     8821 aaacacgctt ttctccggac gatcgtcgga acatttgcgc tagttttctt tttacattta
     8881 tgggagagcc ttcatataca ttttgctgta gatagtctac tgatcaatag tttgatgaca
     8941 ggtattcttt ctggcattgg ttgcggtctc gtctttcgat tcggcggaag cacaggcgga
     9001 acagatatca tttatcaagc cattgaaaaa tattttcata ttaagattgg caaaagtctt
     9061 ttcttgatta cttttggtat tttagttgtc tccttgcttt atttggatct cacacatttt
     9121 ctgtatacat tacttagctg ttctattcta tcttatacat tgaataaagt gaagtatctg
     9181 gaaattggat ctgttttgcc ccaattggaa gcaaaacaga ctacagaaac atttgaacca
     9241 cttgatcctc ttgaacagtt agagcactga ttcttatttt tcactacttt atttaattta
     9301 cagaaatatc attatgtaaa ctaaaatgat attattcagt aaaatcttct ttataaaaaa
     9361 ataaactatt tttgcaaacg atctgcgaaa atagtttgtt tttttatttt gccattattt
     9421 tcttacttat tgggagaaaa aattcgctta aactcaaaaa aatttgagga tacgatataa
     9481 actttcggat agagtataaa ataaggaaac gccgcagcgt ttcctttcca actgtagccg
     9541 aatataaatt tgtatatcac ttatttaaaa tagctatttt ctcccaaaga gtttccttga
     9601 tcatcgatca atccttgtaa tgagcgttct aagataccat ggcttttttt cgattttttt
     9661 tcttctgact gctttgtttc ctctaacgtt tttgttcgat tgaatgttcg tacagacggc
     9721 tcaccatttc ttttttcttg atacggcgtc ggttctgtat cgaacaacag ataagagtca
     9781 tccgtttttt tcatcgattc gattaaatga tcctcagaaa ttttgctttc tctagggtct
     9841 gggataatcg atgcgggtac atatttagga acaaaataag aacgctcccg caccttcgtg
     9901 tcaacagatg cgtttcgtgt agtatgcttg gactctgtcc ttgtttcact ttgtctgaca
     9961 gaacgagagg aatcaccaaa aagttttttt cgtcctgtcg atgtgatttc tgattggtaa
    10021 tggccggtat aatccggtaa ttttccttta tgcttttcca aattttcctt acgcggagct
    10081 gacttcaatc catttgttgc acgacgcttg cgacggattt tctcggtgtt cgtgttcgtg
    10141 aaatgaaatt ctttcatctg ttcaaacggg gactgattct gttcagtcaa aagatcttct
    10201 tgtccgtcaa ataatactcg cttcttgtcg ttggttaatt ttacgcctaa ctcatcatcg
    10261 tacgcaggaa aacggaaatg ttttcgtctg atttctttca ttcaaaccat ccttctcaaa
    10321 aatggaactt ttctcaataa tagcacagat tcattgtttt cagtagcaat gcgctgatta
    10381 ttttaagaaa atagcgatga atttcataaa tatatatata gtaataagac ttaattcgtt
    10441 gtctctctga taactagttc aggaaaaaaa cgacgataac cttgactcgc ccctttttct
    10501 tctatttttt ttaacaacat ttctccacat acttcaccca tacgtataat atcttgcttg
    10561 atcgttgtca atttaggtga actgatttgg tctaaaaata ccccatcaaa tccaatcaca
    10621 ccaaattctt cgggcaagtg tcctccagca tttataatcc ctcttactgc tcctagtgct
    10681 agccgatctg aactacatac aaaacaagtt ttatctgtaa aatctgccca gttttctgtc
    10741 atatatcttt ctacttctgt cgaatgattt ggaaaccgca agattttact aggaagatca
    10801 acttccttca tcacagataa ataaccagtt tcccttgaaa tttcaaaagg ctcgtccact
    10861 tcgataccga tataaataat cgtttgataa tctctttcta aggcatattg cgttgctttt
    10921 gctgtaccat attcattatc gctgtctaca taatcatatc cttcagaatt ttccccaaac
    10981 aagacaactg gtttttccaa acggtcgatc caatcgaagt ctttttttct gacacctgtg
    11041 atgatgtatc catcacaaga accgacgtcg aaggcatcat ttgtaactaa ttggagagaa
    11101 taatgcgctt taccgatccg tttagcgatt cccatcagca aattcatgta atagggctca
    11161 gttgtgtcga tttcttccag tataaataat ttgatgatct gcgaccgatt cgtgacaagt
    11221 gcttttgcag caatatttgg acggtaatcc agttcagcca ttgctgagaa aactaactct
    11281 ttcaattcgt cagtcacctg ttccggatga ttgatgactc gagagaccgt catttttgaa
    11341 acattggcac gttttgcaac atctgctaaa gtgggcatgc tctcttcctt tctaacatgt
    11401 tgtcattctt actatcaatt ataccaaatt ttcctaacag agtttattat agcccaaaat
    11461 aaaaaacgga aaatcctcta tcgtcatgag tgattttccg tttcaattat ttatactttt
    11521 ttatcaaatt ttttgctaaa aaagtggaag cttcttccat tagtggtatt tgtaccatat
    11581 gtcgctgtgt ttttgaggaa cgaaaaacaa tttcttttcc gtaagactta tgccgatttt
    11641 tttctacaaa tcgttccgtt tgtatataag ggattttttc gtcagcttgt ccatgccaaa
    11701 agaacagagg acgtccagct aacttttccg gctgcaatga caaatcatag ctcttaaccc
    11761 atgaaatcaa atcaaaatag tcttttggta cgacataatt atattccgat gcgcgcctta
    11821 cgatttcttt tccatattcc aaaggtgcag gggaacccat caaacacacg cccgctacta
    11881 tatgaggatg tttagccaac aaggcgcatg ttgtcattcc ccccatcgaa accccgccaa
    11941 ctgcaagctg atcatgtaga agacctcttt tttctaaatg cttgataagt gtgtcaaatt
    12001 caaacagatt tccgtagata ctatcccaaa atgtatagga tggaatagaa gaaaccggct
    12061 gtttgcgctc cccatgattc atcgcatctg gcaggatcac acgaatgccc tgctgcgcaa
    12121 tttttcttcc ttgcgtcaaa actaactcct tacttgtctg ccatccgtga taatagatga
    12181 caacgggaat acgttcctct cttaattctt tcagaacaac ttctaacact ggaatatgat
    12241 ggacagaacg tttcaatata attggattca attgttactc acctattttc attaaatttc
    12301 ctgatcgcca tagcaaccat gctccaacag ttgtctggaa caggttcagt gtaccaaata
    12361 atataaatgc aggactgaat ggctcgggaa ataagcacag agaacaaagt cccaccactc
    12421 ctaatgctag cgaaaggagt ggataaatag aaaaattcaa aaaactggca acgctaccga
    12481 aaatattacc aataaacagt atcaaaaaga aaaaaacgct taaaattaaa ccatctgtca
    12541 gcgacatctg aaaaacaatg ttctctacct caattggctg ttgaatcgaa tagacaccta
    12601 agtatatact gagaaggaga cttagcacgt ggctggcaca aaacacacga ttgaccgttt
    12661 tcattttaat cacctaacct atctttataa ttctattata atcattttat catttttttg
    12721 tatgtataaa gtttcaattt ttcttcactt acgatttttt ttgatattgt tgttatataa
    12781 atgaaaggag ttttacaaat gattgatcca aaaatgttgg ggatgatctt cctcattaat
    12841 tttgcttata tcactctgaa cacgttacgt ttcatgttga caatgaaagg ctatcgactg
    12901 attgctccac ttgtcagtat ggtcgagatc acgatttata tcgtcggctt atcccttgtt
    12961 ttagatcgtt tagataatcc actgaattta tttgtctatg cgttaggtta cgcagtaggt
    13021 atcagtgtcg gaattttgat tgaagacaaa ttggcattag gatacatcat ggtcacaacg
    13081 attttgccag caaatagcgc agaagataaa agtttgccgg gtatactgag agaacacggt
    13141 tatggtgtga cacagacttc tgcaatgggg ctggaaggtg agcggctagt tctcgaaata
    13201 ctttctccta gaaaaagcga acgtgaactg tatcgcctga tcaaagaaat cgaagagcgt
    13261 gcttttatca tttcttatga gccaaaatat atttcaggtg gtttctggac taaaaaagtg
    13321 agaaaacgac aaggaaaata actcacaaac ttaaaaactg tctaatatct aaattaaatt
    13381 ttaaatgtta gacagttttt atttattatt ttgattaaaa aacatcgaca tatactcatc
    13441 aatttgttat tatactttat atacttatca atttaatttg gagatattat ggaaattcaa
    13501 cgtagaacca ctaatttttt acatttaggc tctttttttg caactttgac gatcttattt
    13561 tttctatgtt attcatacct taagacctca catgcgcctt ctagtgcatt aggctggttg
    13621 cttttggatc attctgatat cacagaagcc gaagaaaatc cgtttttttt gattttgtct
    13681 tctctttgcg gcttactgtt ttctgtttat ttcggtgcct atttttttca tcgacatcct
    13741 ggtacgttaa acgaagcttc aagcgtattg attgcattta aaacgttttc ttttttagca
    13801 attctttttt attcgtttaa tcacaatacg cttttcttct ttatcatgaa tggtttagtc
    13861 gtgattttat ccatttttac ttattttatt ttttcactca tttttagcca attgaaatgt
    13921 ccgctcttct ttcgattagt tcctgtcacc tgttttattt acagcttgtt ttcctttttt
    13981 gtccttgctt taatgccact gaccaaccct tcgacgatcc aagtcgcagg aaatctgttg
    14041 gatatgctct tcatcgtcag tctaggtgta tttatgtggc aaagaaaaaa caaacaaaat
    14101 aaaaagcatt ttgaagcctg actattacga cttcataaat gcttttttag ttttaaacac
    14161 ttcaatctaa aagaataacc caagattgga taaattatta atgactcgcc attcgtttct
    14221 tagtgattct ggattatcaa atggacttcc taatctaatc agctagttct tcccataaaa
    14281 tgccatactt gactgaatca taatattgat tatttaaaaa tctaactttt cttatcacta
    14341 cttcctttgt cattccacat ttctcaccat ttttttgcat tcctttgttt ccagaccatg
    14401 tagtgaatct aataggtggt agataggcaa aatactcaaa taattctttt aaccataaag
    14461 gaagagaaag gctcctcctg caagagtcag tataattttt gcttactgct ctcttaggtt
    14521 ttactcacta aaactgttcc atattctttg atataagaaa atgcatgcgg tataaatttc
    14581 ttgctcagct cagaaaagat ttgtcgttta agaaaggcca tttcctccat tgtcaatgaa
    14641 ggatccaatg ttggtaattc aatctcaaaa ttgttttttt cgacaatagg taattctaat
    14701 gtgaatgatt cttcttcctt tatagtattc gtcacaagta gagactgatg gaaaatacta
    14761 ggccggcgat ttttatattt attcttacgt atcctgtcaa cgataacttc tatttgatca
    14821 aaaaagtacg attcatttac gtctccaata agttcggcta attctttgaa tgccttcgtt
    14881 acaggaagct gattcttctg tacaaaaaag taattagcca aagtaagcgg gaagtgttct
    14941 atagaggaaa gtgtgataaa acggtacttc tcatttcctg cagttgtcct cagcaattct
    15001 gtctctcggc tgtttcttac tccataaaaa tacgcttctt tccgttcatc ttcgaaacaa
    15061 tacgcccaaa taacttctcc catcgctaat ttttgttcat caacagagag tctcttcaat
    15121 tgttcagcta tggtttcagc agccgaagtg gcttgttgca agtaatcttt aggatcaaat
    15181 attggaaagt tcaaatgata tcttcgttct tccctcttga ttaatcctgc atcgatcaat
    15241 aaatcaagaa aatgggaaaa tttattttgc gaaaattctt ttttcaattc tcttagaatc
    15301 gtttcttgtt ctcgatgttc atatagataa tcggtcaatg aagaaaaaag cggatcatcg
    15361 gtcagttttt gataaaagtt ttccttattt tttgaataat agttcatata tgttctcttt
    15421 tctatccgtt ttattttact taaaaggctt ttacgtaaaa aggaggaaga acaagagtca
    15481 taattgactg ttattctcct ccatttcttc ggcctttagt atgttctatg tttcttttta
    15541 tatcaatcgc ttatccattc attttgaatg cttcatacta ccatttgatt agctaaatac
    15601 agccgtcaat tgaggtacga cttgtttttt acgtgaaacg acacctttaa gcaaagcacg
    15661 gttgttggtc aaagttgttt ggaaagcttc ttctactttt tcttttcctt taccagcaac
    15721 aagtaattct gaatcactgt ctaagatgtt tgtgacaact aatacgaaca gatcgtagcc
    15781 atttgctttc atttcatctt ccattgctgc ttctagctct gcttgtcgat ccatcacttc
    15841 attaaggtcc actgtattga cttgagcgat acgaacgttg gaactgccca ttgggaaact
    15901 ttttgcatcc aaatcaagaa gaaccgcagc tgatttatca cttagatttg ttcctgcttt
    15961 caacatttca agtccataag tgtttagatc gacttcagcg attgctgcaa gttcttttgc
    16021 agctgcttca tcttcaggcg tacatgttgg tgatttgaac aacaatgtat ctgaaatgat
    16081 agctgagagc atgattcctg cgatttcttt aggaattgtt acttggtttt ctttatatag
    16141 ttttaaaata atcgtacttg tacatccaac tggttctgca cgatagtaca atggattagc
    16201 tgtttcaaag tttgcaatac gatggtggtc tactacagct aaaatattta cttcgctgat
    16261 atctgaaata ctttgttgga attcattatg atccacaagc atgacatctg cattttctgc
    16321 tttagctgac tctactactc gtggtgcaga tagctgaaag tggtctaatg cgtattgtgt
    16381 ttcttcatta ggtgtaccta gagcaactgc ttctgtttct ttacctaatt cattttgcaa
    16441 gtgtgaaaac gcaatggctg ccccgattgc atctgtatct ggattttggt gaccaaaaac
    16501 taaaattttt gacatgtcat tcgctccttt gtgatttctc ctatttaata atagcaaaaa
    16561 aacggaaaga agcaatactt atcttctttc cgatgcgacc tatcgcgtta aatattttgt
    16621 atactcttct gtatgaagca atcgtttagc attttcgaca cgttcttttg taggtggttc
    16681 gatcccttct aatggatatt tcaaaccaag tgtttcccac ttgtattttc ccatcgtatg
    16741 ataaggaaga atctctactc tgtctacatt tgacaaggtt tgaataaagt tgtctagtcg
    16801 gatcaaatat tcatcataat cacttcgctc aggaactagt acatggcgaa tccaaaccgg
    16861 tttgttgatt tttgacaaat attgagccat ttctaaaata ttttcattgt cccaatgcgt
    16921 tagtttttta tgctcttcat tatcgatgtg tttgatgtca aataacagta aatctgtata
    16981 cttcatcaat tcttgaaaac gtgaaaagaa aggttcttca tacgtaaaag gttttccgca
    17041 tgtatccaat gtagtatgca tcttccgctc ttttgctttt ttaaatagtt cgatcaaaaa
    17101 atcgatctgc aatagaggtt ctccaccact aacagtaata ccacctttat ctccccagta
    17161 aggtctgaag cgttctgctt tatctaaaag ttcatctgct gtgtattctt tccctccgcc
    17221 aatattccaa gtatctggat tgtgacaaaa ttggcaacgc atgcggcatc cttgcataaa
    17281 cacgacaaag cgcagtccag gtccgtctac tgaaccgaaa gtttcgatag aatgaacata
    17341 gccgattgtt ttttcttcca tttaagttca catcttttct ttgatttcat tttaagtaca
    17401 agttagctgt cgaagcgaag ctttctgaac aaaatttttc gcaattgccg cttcgttatg
    17461 tgtaaaattt acagggacgg aacatacaag tcctgcccct gtaaatcgtt tctttcaaat
    17521 aagcatactg attattcgat tttgatgcga tggctattca acgtcctttc gacgctaagt
    17581 cgaaaaactt ttttcacgaa ctttttacat tctgtcgtgt gaagttctca tcaagacatc
    17641 taattgttgt tctcttgtca agtcacggaa tttaactgca taaccagata cccggatcgt
    17701 caagttcgga tatttcattg gattttccat tgcatcacgc aataaatcat tactgaatac
    17761 attgacattc aaatgataag ctccttttga gaagtatcca tctaagacat tacgcaagtt
    17821 ttcgattctt gtatcttgtt cttttccaag acctgaagga ttgattgttt gggtatttga
    17881 aattccatcc aatgcacagc cgtaattcat tttagctgtt gagttcaggc tagctaataa
    17941 cccactttgt tccgcattgt aacttggatt tgctcctggc gcaagtggtt ttccagcttc
    18001 acggccatca ggagtatttc ctgtattttt accgtaaaca acatttgaag taatcgtcaa
    18061 taatgaagtt gttggttttg agttgcggta agttttatga cgtttgattt gtcccatgaa
    18121 gtattccaag atccatgaaa ctaattcatc tgcacggtca tcatcatttc cgtatttagg
    18181 gaagtcgcca tccacttcaa aatcaactgc tattcctttt tcattacgga ttgcttttac
    18241 ttttgcatat ttgatcgctg acaagctgtc tgccgcatga gagatcccag caatacctgt
    18301 agcaaatgtg cgttgcaagt cagaatccat caaagccagc tgagctgctt cataagaata
    18361 tttatcatgc atataatgaa tgatgttcaa cgtattgaca tatagttctg ctaaccaatc
    18421 catcatattc atgaagttat gtttcacttc ttcaaagtct agtatttctg atgtgattgg
    18481 acgatattct ggtccaactt gggcgccagt cacttcatcg actccgccat tgatggcata
    18541 taatagtgtt ttagccaagt tagcacgagc gccaaagaat tgcatgtctt ttccgacaac
    18601 tgttcctgat acacagcaag caatcgcaca atcatcagaa ccccattgtt cacgaagctg
    18661 attatcattt tcgaattgaa tcgaagaact ttcgatagcg attctgctag catatgttct
    18721 gaatccttct ggaaggtgtt cagaatacaa aacagtcaag tttggttctg gtgaaggtcc
    18781 catatttgtt aatgtatgaa gcagacggaa atcattcttt gtaactaatg aacgaccatc
    18841 taatcccata cctgcaatgg ataaagtagc ccagataggg aatcctgaga ataattggtt
    18901 atattcaggt gtacgcgcga atttgaccat acgtaatttc attactaagt ggtcgatcaa
    18961 ttcttgtgct tctttttctg tgattactcc attatccaaa tcacgttgga tatagatatc
    19021 aaggaatgct gagatacgtc cgattgacat cgcagcacca ttttgtgatt tgattgctgc
    19081 taaatatccg aagtatagcc attggacagc ttcttttgca tttgcagctg gtttagaaat
    19141 atcatagcca tatttcgcag ccatttcttt catttgcgct aatgcacgat attgttcagt
    19201 gatttcttca cgtaaacgaa tcacttcttc actcattgta tgataaccag tcatatcatg
    19261 atcttttttc ttttgttcca tcaaatagtc gattccatac aatgccacac gacgatagtc
    19321 accgatgata cgtccgcgac cgtaagcgtc tggaagccct gtaatgattt tgtttttacg
    19381 agcagcacgc atttcagcag tataagcgtc aaatacacct tgattatgtg ttttgcgcca
    19441 gtcagtgaaa atatgtgtca attcatcgtt tggtgtatag ccattgcttt ttagcgcatt
    19501 gttagccata ttgattccgc cgaacggcat gaatgcttgt ttcaaaggtt tgtctgtctg
    19561 tagaccgacg attttttcca aatctttatc caaatagcct gcatcgtgtg aagtaatagt
    19621 tgatacgatt tctgtgtcca tatcatagac accgttacgc tcgaattgga tatcatttaa
    19681 cttttgcaat tcatcccata atttttctgt tgcttctgtt gggccttcca aaaagctgtc
    19741 atcaccgcga tattcagtgt agttattttg aataaagtct ctagtgtcta cgccttcttt
    19801 ccatttggta cctttaaatc cattccattg ctccattgta tggacctcct aaatttctgt
    19861 tttatgtaac agtttttacg tgattagtat aacacagcac cctatctttg caagggtttt
    19921 cttgtttttt atttaacaat ttttatgttt tatttacata tatttaaatc aacgttgaca
    19981 taccaacatt taagcattgt gaacactttc atcttttttt gcaaacgtat aaggatttat
    20041 taaaaatgaa tgaaaaagag acgccacctg tattaataca gatggcgtct cttcattaaa
    20101 atactacaac agttacgact cgatgaaaat ctcaggagca tcgataactt cgatgacttc
    20161 tccacctttt ttctcatcca tcgcaaatga tccattcgat gttcgatcac ctatagggaa
    20221 atcagttggg tcaatcgtta actgctgccc tttttgattc atcaaggtta tttcttttga
    20281 tcttccttcc gacatataga taatacggtg cggatttttt ttcagctcac gcatgaccgt
    20341 cactccccgc ttcgcacgtg aagtttggct gatttcttga gcaagcatgc gtttaacagc
    20401 tcctcgctga gtaacgatta cgatcggcgt atcaccttct gctaacacaa gcagcccgtt
    20461 gataatccta tctccatctt tcaaattcat agacttcact ccagctgcct ttgctccaac
    20521 aacgggaaca tctgttaaag gatagcgcaa acccattcct tgatgcgtta ctaagaaaac
    20581 atctaagcct ggctgatctt ctttcagata cacagcaatc agttcatctt cttccgcctt
    20641 tagcttcata cagctgagcg gacggctctt ataggtgcgc catggttcga actctgtcat
    20701 tcgtgtttgc ttgatcaatc cattcttgct gatgaataca aatgttttct ctgcttgaat
    20761 tttttgatat gggaaaacag ctaaaatcga ttcgtctaca gacagattgg agattgtttg
    20821 agaaatgtgc tcaccagcat ctttccattt caaatcgggt agttcatgga cagggcggta
    20881 gatcacattt gctttatttg tgatcagaag aacatggtcc aatgtactca attcacctga
    20941 gtatagcaag tagtcgcctt ctcgcatccc gatttcttct ggtttggaag cactataaga
    21001 acgaaggctt gttcgcttca catagccttc tcgcgtcaca ctgacaatta cgtcttcttg
    21061 tgccactaag acttgcgtat caattttgat ttcttcgatt tcgtcttcga ttgtcgttag
    21121 acgagcggaa gaataatttt ttttcacttc tcgcaattct tttttcataa cagagaaaag
    21181 ctctttgtca tttgaaagga ttttattcaa ctctgtgatt tgcgcaatca agctttcgga
    21241 ttccttttga agctctgtga tatccgtgtt cgtcaaacgg tataattgca atgtgacaat
    21301 tgcttctgct tgttcttctg taaattgaaa gacgtcgact aaattctttt tggcgtcttt
    21361 tttgtcttta ctttcacgaa tcgttgcgat tacttcatcc agaatcgata aagctttcat
    21421 caatccttct acgatatgct gtcttttttg agctttggct aaatcgaatt gactacgttt
    21481 tgttatgact tgctttcgat gctcgatata acttcttaaa atgtctttca gtccaacttg
    21541 atgcggagtc atatggtcga tagcgaccat attgaaattg taattgatct gtagctcagt
    21601 gtttttgaac aaataattca aaattccttg agcattggcg tcttttttca attcgacgac
    21661 aatttgcaga cctgttctat cactttcatc tcgtacttca gctattccat cgattttctt
    21721 attcaaacgg atctcatcca tttttttcac caaggtcgct ttatttactt catatgggat
    21781 ttctgtgatc acgatttgct gtttattacc cttcattgcc tctatctttg ttttcgaacg
    21841 aagaataact tttcctcgtc ctgtttcata agcttttttg atttcatctt ttccttgcaa
    21901 gatccctcct gttggaaagt caggtccagg aatatattcc atcaattttt caaggctcgc
    21961 ttgtggatga tcgatcatat agattgtgcc atcgatcact tcagctaagt tatgagtcgg
    22021 gatttctgtt gcatatccag cagatatacc tgtcgatcca ttgacgagaa ggtttgggta
    22081 tcgagctgga aggactgttg gttctttttc tgtatcatca aaattccaca cgagatcgac
    22141 tgtttctttc tcgatatctg ctagcatctc tccacttaac ttggataatc tggcttcagt
    22201 ataacgcatc gcagcaggtg gatcaccgtc catactcccg ttattcccgt gcatttcgat
    22261 cagtacttcc cgcaacttcc agtcttggct catgcggacc atcgcttcat aaatactgat
    22321 gtcaccatga ggatgataat tccccatgat atttccgaca gattttgctg atttacggaa
    22381 tcctttgtca tacgtattgc catctttgtt catggcaaat aatatccggc gttgcactgg
    22441 cttcaatcca tcacggatat caggcagtgc acgttcttgg ataatatatt tggaataacg
    22501 tccgaagcgg tcacccatca cttcttctaa agttaattct tgtacttctt gtcgattttc
    22561 catcaggtga cctcctattc tacttcaaat aactgattgt tttcattttt atctgctcgt
    22621 tcttcatcta ataaatcatt agaaactgaa ggagagattt cagtatcctc ttttttatct
    22681 aagatactgc catcttcttc gagcgtaaat tgcacgtgat tttcgatcca ttttcttcga
    22741 ggttctactt tgtcacccat cagtgtggtt actcgacgtt cagcttgcgc agcatcatcg
    22801 atacggacgc ggatcaacgt acgggaagtc ggatccatcg ttgtttccca caattgttcc
    22861 gcattcatct ctccaagtcc tttatatcgc tgcagcatat atcctttgcc gactttttta
    22921 atcattgctg ccaattcgtc atctgtccac gcatattcaa tgacttgctt ctttccttgt
    22981 cctttggata ctttatataa aggcggtaac gcgatatata ctttcccagc ttcaatcagc
    23041 ggtttcatat aacgataaaa gaaagtaagc agtaatactt gaatatgggc gccgtctgta
    23101 tccgcatcgg tcatgatgat tactttgtcg taattacagt cttcgataga aaactcagga
    23161 ccgactcctg caccaatcgt atagatcatc gtattgattt cttcattttt caagatatct
    23221 tgcattttag ctttttcggt attgatgact tttcctcgta aaggtagaat tgcttggaac
    23281 tttctgtctc ttccttgttt agcagatccg ccagcagaat ccccttcgac taaatacaat
    23341 tcatttttct tagggtttcg ggattgtgcg ggtgtcaatt ttcctgaaag aagagattcg
    23401 ccttttttac gcttcttccc atttcggctt tcttctctgg ctttacgtgc tgcttctctc
    23461 gcttctctgg ctttgattgc tttacggacc aacatctggc tcatttcgct attttcctgc
    23521 aaataaaagc ccatttgttc actgatgacg ttatctacta cggtacgagc aactggcgta
    23581 ccaagttttt cttttgtttg cccttcaaat tgcagaagat tttcaggtac acggatagaa
    23641 agtacagcag ctaacccttc tctgaaatca ctaccttcca gattcttgtc ccgttctttc
    23701 agcaaaccaa cttttctcgc atattcatta taagatttcg tcatcgccgc tttcatacca
    23761 gcttcatggg ttcccccatc ttttgtccga acgttattga caaaagataa aacattttct
    23821 gaataaccgt cattgtattg ataagcgacc tctacttcga taccttcttt ttctcctgaa
    23881 aaataaacaa ctggtgtcaa tgtatctttt tcttcattca gataatcaac aaattctttg
    23941 attccttctt cgtaatgaaa aatttccttg actggttctt ctccacgaag atcagaaaga
    24001 gagattttaa cgccttttag aagaaaggca gattctctta accgttcggc taaaatttca
    24061 tatgaaaatt tcgttgtact gaatattgta tcatctggta aaaaatggac agtcgtcccg
    24121 tttgcttttt ttgtttttcc tatctttttc aaagtaccgt caggtttacc gccgttttta
    24181 aatttctgct gatactctac gccatctcta acgatcgtta caattagcca tttcgataag
    24241 gcatttacca cactggctcc tacaccgtgc agtccaccag aagttttgta ccctccttga
    24301 ccaaactttc cgccagcatg cagcacagta aaaatcactt caactgttgg tattccggaa
    24361 gcatgcattc ctacaggcat cccacgtccg ctatctgcaa cagttatact attgtcttca
    24421 tggatggtca catcaatctc actgccataa cctgataatg cttcgtcaac tgcattatcg
    24481 acgatttcat agactaaatg atgcaagcct cggctgtcag tggatccaat gtacatccct
    24541 ggtctttttc taactgcctc taatccttcc aatacttgga tggacgagtc attgtattcg
    24601 ttgtttactt tttttgccaa ggcaaacgct ccttcaataa tactttgcgg caaaaccgca
    24661 ccacgattat catactagaa aaggtcgtga aaaaaaagag ggtagacgag aaatcaattt
    24721 taattatctc ctaaccgctt tttcgacatt cccctctatc gatcatctct tctttgtggt
    24781 catttttatt tttggttttc tttcaactta ccaagttcaa tcttaataca acgatccatt
    24841 acgatatctg tacgtcctgc ttttcttagc atctcagctg cttctttgtt ttcaatccct
    24901 aattgtgccc agaacacttt agcatcagtt ttcaaaaaat cacctgctat ttcaggtaaa
    24961 aattcactcc gtctaaatac atctacgata tcgattggat catcgatttc tgtcaaattc
    25021 gcatagactt tctcgcctag aatttcttca ccagccaata atggatttac tggtatgatt
    25081 ttatatccat tgtcttgcaa tacctgtgca accatgtaac ttgttcgttc tggtttattg
    25141 ctcaagccta cgacggcaat attttttgct tcttccaaat agttgaaaat cgtttcttgt
    25201 gttggatttt ttacagacat ttctgccacc ccttgctttt ctttttattc catctattat
    25261 acttgtatct ttcatttttt caattgttcc tgttacctat tcatgctaaa ataaaggata
    25321 gttttcaact tgaaagaggg taaaaaatga aattgatctt attacttatt ttagcatatc
    25381 ttttaggttc tattccttcc ggtgtctgga ttggcaaatt gtttttcaaa aaagatatcc
    25441 gacaacacgg gagcggtaat actggaacga ccaatacatt tcgtgtatta ggcaaaacag
    25501 ccgggattgt tgtcctgctt atggatattt taaaaggtac attggctact tgtttgccga
    25561 tgatcttcca cctttctggg attaaccctc tttggtttgg ggtatgcgcc attcttggcc
    25621 atacatttcc gatttttgct gggttcaaag gaggaaaagc tgttgcgaca agtgcaggaa
    25681 tgcttttagg atttaatcct gtattttttg tttattcttg tatcatcttt atcgttagtt
    25741 tattttgtac aagtatggtg agtttgagca gtatgatcag tgcagtattg atcactttat
    25801 ctacgatcgt ccttccttat gtagctcctg tgattttggc taagcccaat tggttactga
    25861 cgatcattgc ctttttagtt tcttccttta tcttttatcg gcataaagac aatatcaagc
    25921 gtatcagaaa ccatactgaa agtcgaatcc cgtttggttt gaatagcagc aagaaaaaat
    25981 cctgatactt tttcattcca aagagataaa acgggagtgt gacaaatcga tgtcacactc
    26041 ccttattact tacaggatag cttttttaca caccttggta aacggtgttc cctgctaact
    26101 tctcggtcac aacctcttac ttcactgtga tggaatattt tgtcttgaag atttcatggg
    26161 cacctagttg attgatccct actttttcca tcaagtttcc actactgttc accgtgtcag
    26221 cgattccgca ccacggttcg atacaaacga aaggcgcttc ttttggataa ggagaccaga
    26281 tccctacata aggcatatct ttatagctta aagttacgct atgggaagat ttttcacttc
    26341 gaatggcgta cgcatttaga ccccttgttt caaaaaccaa ggcatcttgc tcaaaaagtt
    26401 cacgattcaa agccagattc gtatttgtct gacctaacgt cttttgatcc atatcgatga
    26461 atgggccttt caatggtagg cgtaatcttg atttcaatgg agaaaatgcc agatagaaat
    26521 cttcaaatga caatccttct tcaagaggta cattgaaagc aggatgtcca ccgatagaaa
    26581 agaacatttc tttttcaccg gtatttgcca cttgataatg aaccgtgatg ccgtctcctc
    26641 ctaattcata gctgatcact aattcaaaat caaatggata cttttctaat gtctccggcg
    26701 tactccttaa gatgaaacta gccatttctt gtccatgttc aatgacttca aaatccatat
    26761 cccgagcaaa tccgtgttgc cccatttgat atgttttccc ttgataaaca tactgatcat
    26821 cttttaaacg tccaacaaaa gggaataaaa ccggtgcatg tctgccccaa tacgctggat
    26881 caccttgcca gatatactct aaaccatgtt cttttgattt cagactgatc aattccgcac
    26941 cgtgttcagc gatttcggcg atcagctggt cattttgaat aataacagtc attgccattc
    27001 ctccaacttc gacttacttt ttaaaatggg aaggctggaa caaacatttc tatctgcccc
    27061 agtcccctta cttctaataa ctgtgttttg ctaactcgtc tttaaaacgg gaattcaata
    27121 cttttaaata agttcccttc atgcctaacg aacgagattc aatgattcca gctgattcca
    27181 attttcgtaa agcattgacg atcacagaac gagtgatgcc gatactatcg gcaatattag
    27241 aagcagtcag acgaccttca tctccatcca atgcttcaaa gatagcttgt acagccttca
    27301 attcgctata agataatgtg ttgattgcca tttggacagc cgttgcactc cgtacatctg
    27361 cttcgatgct tcgagacttc tgataaagga tctgcatacc gacaaccgta gctccatatt
    27421 ctgctaagac tagatcgtca tctgcaaacg attgttccat acgagataag ataatcgtac
    27481 ccaaacgttc gccagctcca aagatcggaa cgacagtcgt cagaccaaat ggatatttct
    27541 ctcttgactc taccggaaat gcagtaatat cactagtaat tgggatatta gcttcagttt
    27601 tcatcaactg tgccactgta tcagtataag attcaggaaa ttgtttctca acaaacattg
    27661 ttttgattcg ttcattgttc acatcgtgac gttcattata acctagtaat actccgtcac
    27721 ttcctatgat ataggtgttg ctgtcaagaa taccacctag tgtgacagcc attttatcgt
    27781 aaggcaaatc tgcttgcatg tcaaaagtat tcttttgctg caaaagtgtg tttatcttgc
    27841 gggttttcgt tagcaagtct gtcattgtcg tcctccgatt ttttataaaa tatagcgact
    27901 taaatcttca tttgccgcaa ttgagccaag tttgtcatcc acatatgctt ctgtgatcgt
    27961 tatttctccc atttgcatat ctggtgcttc aaataataga tcttctagta gtttttccaa
    28021 aatggtatgc agtctgcgtg cgccgatatt atctgtgtca cggttgacat cgaaagcgat
    28081 ttgagcgatc cgttcaattg cttcttttgt aaacgtaact gacacatttt ctgtaccgat
    28141 caacgcgacg tattgtttta ctaaagcatt atttggttcg gtcagaatct tcacaaaatc
    28201 ttcagctgtc aaatcatcta attctacccg tatcgggaag cgtccttgaa gttctggaat
    28261 tagatcactt ggtttagaca aatggaaagc tcctgaagca atgaatagga cgtgatctgt
    28321 ttggatgatc ccgtattttg tgtttacttg tgaaccttcg acaattggca atatgtctct
    28381 ttggacgcct tctctggata cttctccaga ttgctgtgat ttagaagtga tcttatcgat
    28441 ttcatcgata aaaataattc cactttcttc cgctaatttg attgcctcac tatggatatc
    28501 agcatccttg actaattttg ctgattcttc cttgatcaat aactctaaag cttctttgac
    28561 tgttaccgtc cgttccactt ttttcttcgg tgtcaaagca cctagagttt catttaggtc
    28621 gatccccatt tgctccaatc cattgttcat cattggtgca ggtttctttt ggtcttcaac
    28681 ttcaatggtt acttcacgac tatccagtaa acccttttgt agttgttcca agactgtacg
    28741 gcgattgatt cgaatatctt ctgtcacttc ttcttgcggt tcagcggtat tttgctgact
    28801 agcattaaaa agattcatca tttgttcaaa ttgattagtg gattgtttct gttctttttt
    28861 gataccaggt accaagattt ttaccaaacg tttttctgca ttttttttag cacttgtgta
    28921 tacacggctg tactgctctt tttctacgat ttggatcgca ttttctacta aatcccgaac
    28981 cattgattct acatctcttc cgacataacc gacttcagta aattttgttg cttcgacttt
    29041 gacaaatggt gcattgacga tttttgccaa acgtcgtgcg atttctgttt taccgacccc
    29101 tgtaggtccg atcatcagca tattttttgg tgtaatatct tgttgcattt tttcatctaa
    29161 ctgcaaacgg cgatagcggt tacgcaaagc aacggcaaca gatttttttg ctgcgtgctg
    29221 tcctacgata tattcatcta attcacttac gatttgtctt ggtgtttgtt ttaattcata
    29281 catatctact cacctcttac agttcttcta cgataatatt atgattagta aagatacaga
    29341 tatctgcggc aatatttaac gcattttctg caatttcttt cgcactcatg tcgttttgag
    29401 catagttttt cattgctcgg gctgcagcca acgcaaaatt ccctcctgat ccgatagcta
    29461 agataccatc atctggtgtg ataacttctc ctgtacctga aacaagaagc atttctttat
    29521 cattcattac gatcagcatc gcttcaagtt tttgcataga ttgctgtgtc cgccattctt
    29581 gagctaattc gacagctgcg cgttgtagat tcccgttata ttcgtttagt ttgccttcaa
    29641 atttttcttc taaagtaaac gcatctgcaa cacttccggc gaaacctaca acaacttctc
    29701 cattgtagat acgtcgtact ttctttgcag tgcctttcat gacaacagat tcacccattg
    29761 ttacttggcc atctccagcc atagcaaatt tcccgtcttt ttcgacggca cagatagtgg
    29821 ttgaatgaaa tggtgattcg accatgtttg tttcctccta aatttgttct tttccttatt
    29881 tttacgctct tggatggaaa gaacgatagt ttttttgtaa actttctttt gttacatggg
    29941 catagatctg ggtagtcgat aaattggcat gtcctagcaa ttcttggact gtccgcaaat
    30001 ctgccccatt atttaataaa tgagtagcaa atgtatggcg cagcatgtga ggatggatat
    30061 cactatccaa actgcttttt ttgatcattt gattcaagac atattcaatt ccagtaggcg
    30121 tgattggttt tccatgatga ttcacaaaaa cgatatcatg ctcttcgtga tattttgtca
    30181 tcaatacctg gcggccttcc ctgaaatatt cttgcagagc atcttgagca aaagaaccta
    30241 gaggagcata tctctctttg ttccctttac catggatcaa catgacctct gaatcaaaat
    30301 caatgtctga taccgacaaa ctgctacact cacttaaacg gatgcctgac ccgtaaagga
    30361 cttccagtaa agcgcggttc ctcaaatcca aaggactatc tcctgctacg ctgtcaaaaa
    30421 gtgcttgcat ttcattttca taaaaaaaac gtggcagtct caaatttttc tttttgagat
    30481 gaacgtaaga aaatggattt tcttttatca cttcttcttt gagaagatac tgataaaacg
    30541 aacgtaggct ggctatcttg cgactgatag aatttctgct atagctagga cgatgatcag
    30601 ctaatgcact caaatagaca cgaaccgtaa aatattccgc cttcagcaga tcagcgtctc
    30661 cagattcctc caaaaaatgt ttgaaatgga gaatgtcttc ttcatatgct tctttcgttt
    30721 tttctgaata tcctctttcg acaatcaaat aacgcaaaaa tttttgttcc cacgtggctt
    30781 ctgtcatttt ctcaccttcc ttttgtccca gagaataatt tagcacagcg tttataaaaa
    30841 gacaaataaa ttgtcagaat ttaaccaata tttctaagtt tgttcacaat tggcgcaatt
    30901 cctcacattt tgtttgagaa attcttaaga aaaacgcaag aaaaagagcg agactatccg
    30961 tctcaccctc ttcatggagt ttccttactc atttgggatt gcagtttttt ctaattctgt
    31021 ttttattgcc tcattagctt ttaaagctcg ttgtgcaatt gcttcatatc ttgctttttt
    31081 gtctcgaatg cgctctggca gttcaggaaa cagaccatag ttggcattca tcggttggaa
    31141 atgttttcct tccgcatgag taatgtagta agccatactt ccaatagctg tttcttgtgg
    31201 aaactcgact ggttccattt cttttgctaa gcgtgcggcg ttgattccag caagtagtcc
    31261 gctcgctgca ctttcaacat agccttctac accagtcatc tgacctgcaa agaacagatc
    31321 ttcgcgtttc gttgattggt aagtcggttt cagcaattct ggcgaattca taaagctgtt
    31381 tcggtgcatc acaccatagc gaacgaattc agcattttct aacccaggaa tcatccggaa
    31441 aacacgtttt tgctcgcccc atttcaagtg agtctgaaag cccacgatgt tgtataaaga
    31501 agctgcagca ttgtcttgac gcagctggat aacagcataa ggacgtttgc cagttttagg
    31561 atcttccaat ccaactggtt tcataggtcc gaaaagcatc gttttgaatc ctcgctgtgc
    31621 cattacttca attggcatac atccttcaaa atatttttct ttctcaaaag atttaagttc
    31681 tgccacttcg gcattgatta gtgcctcatg gaaagctttg aattcctctt ctgtcatcgg
    31741 acagttcaag taagctgctt ctcctttgtc atagcgggac ttcaaatata ctttatccat
    31801 atcgatcgta gctttgtcta cgattggtgc agctgcatca tagaaataaa aaccatctga
    31861 accattgaat gctttgatgc tttctgctaa tggatgagaa gtcaaaggtc ctgttgctac
    31921 tacggtgatt ccttccggta tttcagtaat ttcttcgttt atcactgtta ctaatggatg
    31981 ctctttgact tttcgggtaa ttgtttcaga aaaagaatcg cggtcaacag ctaaggcacc
    32041 accagctggc actgctgttt catctgccga agtgattact accgaattca atcggcgcat
    32101 ttcttctttc aataacccta ctgcattagc caaactgttt cctcttaatg aattggaaca
    32161 tactagttca gcaaaattac ttgtgtgatg cgcctcagtc gatttgactg gacgcatttc
    32221 atataaacgg acagggactc ctgcttgtgc gatctgccaa gcagcttcac ttccggcaag
    32281 ccctgctcca acaacattta ccattttcaa tgaaagaacc tcttttctat tatttttgga
    32341 tgtcttcttc gtaatctcca tttacacaga ctacttgttt accgcctttg actttcttct
    32401 cgaccagata tccgtcacat tttggacaat ttctgcccac tggtttatcc caagaagtga
    32461 attcacattc tgggaaacgg gaacaaccat agaatagtct gtttttctta gattttcgtt
    32521 caatgacttg tccttcatga catactgggc aagtcacacc gatttctttt acgattggtt
    32581 tcgtattccg acaatcagga aaattactgc aagcataaaa cttcccatat ttccctaatt
    32641 ttatcaccat cggatgtcca cagacatcac aatcgaatcc tgctggttca tctttgattt
    32701 gaattttttc gattttttct tccgcattcg tcagttcttt ttcaaacggt ttatagaaac
    32761 gatcaaccac tttgacccac gcttccgtgc cttcttcaat tttatccaaa tctccttcca
    32821 tttctgctgt gaaatggata tcgacgattt gagggaagaa ttcacagatt aatgaattga
    32881 caatttctcc tagttcagtc ggctcaaatc ttttttgtgt caattttaca tagtagcgtc
    32941 tttggatcgt atcaagtgtt ggtgcataag tggaaggtcg ccctaccccg ttttcttcta
    33001 gtgcacgaat caacgtagcc tcactaaaac gtgctggtgg ttgagtaaaa tgttgttttg
    33061 gttcaatatc aacagattgg actacatcgc cttcttcaag ttctggaaga atattttctt
    33121 tctcttcttt gccgtcatct ctaccttcca catacacttg catgaatcct ttgaatttga
    33181 tttttgaacc gttcgcaatg aagatgacac cattttgttc taatgtcact ttcattgtat
    33241 ctaaaatagc tggtgtcatc tgactagcca caaaacgtga ccagatcaat gtataaagtt
    33301 tcaattgatc tttatctaaa tattgtttga gttcatctgg tgtacgaagc acactcgttg
    33361 gacgcacagc ttcatgggca tcttgtgcgc cttgagcatt tttgatcttt cggtgatcat
    33421 gtctagaaaa ttcttttcca tacgtatctt caataaatgc tgcggcctct gcttttgctg
    33481 tatcggcaat ccgggtagaa tcagtacgca tgtatgtaat caagccgact gttccttgtt
    33541 tacccaaagt gattccttca tataattgct gtgctaccat catggttttt cttgttcgaa
    33601 agtttaactt acgggcagct tcttgttgca ggctacttgt agtgaaagga ttcgcagggt
    33661 ttcttttgcg ctctttcttt tctacttttt taacttcgaa gtctgttcca tcaattctag
    33721 cagtgacttc ttttacactt tgtgcatctg gtaatttctt tttcttaccg tcgattcccc
    33781 agaaatttgc tttgaatttc ttgcgagctt ttttaaaatt accgtcgatg ctccaatatt
    33841 cttctggaac aaattctcgg atctcttttt cacggtcaat aataattttt aaagcgacag
    33901 attggacacg tcctgcactt aaccctttct tgaccttacg ccagagaata ggactgatcg
    33961 aataaccaac gattctgtct aaggtacgac gagcttgctg tgcatctact aaatctacat
    34021 cgatcgttct tggttcctta aaagctgctt tgactgcgtc ttttgtgatt tcattgaaga
    34081 ccacccgatt tttttctttc agatccaacc caagtaggta cgctaaatgc caagcaatcg
    34141 cttctccttc tctatccggg tcacttgcca agtaaacttt ttgagctttt tttgctgcgg
    34201 ctttcaggct tttgatgaca tcgccttttc cgcgtataga aatataatgg ggttcataat
    34261 tgttttcaaa atcgataccc attttacttt tcggtaaatc tcttatatgg ccaacactgg
    34321 ccattacttt atagtttcgt ccaagatatt tctcaattgt cttggctttt gcaggtgatt
    34381 ctacaatcac taaatattta tacgccatta ctgaatggac tcctttccat tgtcgtgttc
    34441 ctactattaa aagaggattc atacaaatcg tagctaatca tatccattca gaaaacgttt
    34501 gtcaagaaaa gcaaatgaaa agtatggtgt tattctttaa attctgccaa gatatcttca
    34561 cccgaaaccg tgcaaactgc accgtcttgg atcaaatgat gacatccggt agaatgttct
    34621 gttaaaatat ttcctggaac agaaaaaact gttcttccaa gatccaatgc ttgctgtgct
    34681 gttatcagag agccgctttt tttcttggct tcaaagacac atgttccttt agacaaagct
    34741 gcgataatcc gatttctcat tggaaaacaa tgctttttcg ggccggattg aggaggatat
    34801 tcactcaaaa gaagatgatc atttgcaatc acctcttgca agtcacgatt ttcagcagga
    34861 tagacttgct ctatccctgt tccaatgact gcgattgtcc gtccaccatg agagattgct
    34921 gcttggtgac cgtatgtatc tatccctttc gcgcagccac tgacgatcac atatccagct
    34981 tctatcactg gttttagtaa ataataaact gtttttttgg ctaaagcaga agtgtgtctt
    35041 ccaccaacaa cgcttaacat gttacaagaa agtaaagata gatcaccatt ataaaacagt
    35101 acaattggcg gataggtcaa gtgaagcagc tgagggggat atttgggatc aaagcaagtg
    35161 ataaacgact gtttcgattg gattttgccc cagttagcgt gaatttcctg ccaacttttg
    35221 cgaaacagct cccggtgttt ggttatttta cctatcttaa tgatgtcttc aaatccgatt
    35281 tctttataag gatactgcat catccagtta gcaagtgccc attttccttg actactgatt
    35341 ccttttgtat aagcaagttt caataaattt tcttctattt gatacatcat aaaaccgcct
    35401 ttcgtctctc tttctaataa gatacgtaaa agcggctgtt ttttattgta aatatttttt
    35461 tacaggtgca aaacttttac gatggattgg cgtaattcct tgtcgttcaa gtccttctaa
    35521 gtgttccttt gttccataac ctgcattatg cgagaaacca tatccaggat aaagcacgtc
    35581 atattctttc atcaattggt ctcgatatac tttagcaatg atacttgcag cagcaatcga
    35641 cacagatcgt acatcccctt tgattatttt ttcctgctga ataggcaaat ccaaggtcat
    35701 cgcatcgatc aacaaatagc ttggtacaat ggacaatttt tctactgctt ggatcatcgc
    35761 taatttactt gcttcataaa tattcacatc atcgattgtc tgctgatcaa cgatcccgat
    35821 cccgattgcc agggcttttt cttgaacttg ttgataaaga agttctcgct ttttctctga
    35881 taattgtttg gagtcattca gccctaatat gatctcattt ttcggcaaga taactgcagc
    35941 tgccacgaca ggtccagcta atggtcctct tcctacttca tcaatgccgg caatccattg
    36001 gtgaccttgt gcgtaccctt gcttttcaaa gcaaaacatt tcttcatatt tttccttaat
    36061 taatgcttcc tttttcaatc gtcgttcaaa agaagccagt gcttgctgca cgcctttgcg
    36121 tggatcattt cttaatgatt ctagtgtagg atcatctatt ctctgtatgc ttttcaatcg
    36181 ttctttgata ctttggatgg attcagtcat cacttttttg ctccatttct tcgcaacgat
    36241 ccagtgtgta tcgtccaagt tttccttgac gaatatcatg cacgactaat tcgctgccac
    36301 gatcatagtc ttctttatac ccacgttttg ctgtaatatc catcagtaat tccggtgcca
    36361 atttttcttc ttgctcgatt gataaaccat aacgatcgct gattcttcct gaataatatc
    36421 gggcaaaaaa gtctaatccg taaatcgcta aatcatctaa atggacaagc tggtctttga
    36481 tcgcgcctgt cagcgctagt tttttgccga tttcttcatc ttcaaatttg ggccataaaa
    36541 tccctggtgt gtctaacaat tccaactcat tacctaaacg aagccactgc tgaccttttg
    36601 ttacgccagg cttatttcct gtctgtgcaa ttttcttgcc tactagtcga ttcatcaacg
    36661 tagatttccc aacatttgga atacctaaga ccattgcccg aatagcgcga ggcttgatcc
    36721 cccgagcagc atctcttgcc cgtttttctt tcaatgcttc tttagccgca ggtactagac
    36781 ctttaattcc tttactttct tgtgccgtga tagctaatgc aagatggcct tgtttacgaa
    36841 aatattcttg ccacagcttt gtctgttgtg gatctgccag atccgcttta ttcaataaaa
    36901 caaggcgagg tttttgctga atgatctgat ctagcattgg attacgagaa gataaaggta
    36961 atcgtgcgtc taccaattca aatacgatgt ccacatattt cattttttca gaaacttctc
    37021 gtcgggcttt tgccatatgt cccggaaacc attggatggt cattgttctc tccattcctt
    37081 tcataccgga atattccccg gctttacttg tttttttctt tttcaatata aattcacttt
    37141 tttattataa agaaattcca tctattagtt aagtgaaagt gaaccagtcc tcattctatc
    37201 acatcttcac ttttttgatg atgcaaattt ttattttggt ttctatatat gaatctaaat
    37261 ttttgacagc gtttcctaaa taagagatga tagacgaaca aaacagaaag gagacgaaac
    37321 aaatgaatag tatggttttt gttaattttc ctgttgctga tgtcaatcgt tccgttgctt
    37381 tttatgaaaa gctgggtttt aaaaaaaatg aagaattttc tactgaagaa gctggttcaa
    37441 tggtatggga tgacactttt tggataatgc ttctctctca tgatttttat aaaaaattta
    37501 taaaagataa agaaatagct gataataaaa aaacaagtgg tgctttgatt tcgtttagtg
    37561 ttgaaaatgc ggatgaagta aaaaaatttg ctcaaattgc aaaagaaaat ggtggtactt
    37621 tccacgaagt agatatggga atgcctgaag aagaaatgtt ttcattagaa gtccaagatc
    37681 tagacggaaa tacattagaa cccgtatgga tgaagatgta agcagataac taatctgacg
    37741 ttttttataa caaaaaaaca aaggcggatg atacgataag tattctccgc ctctattttt
    37801 tttattcgta caatctcttt tttacagttt ataaaagcag tcttctcacc ctttttttaa
    37861 ttgttagatg ccagtgtatg taaatcacca atgtgtcatg acacattggt gattttatgg
    37921 tatcctttta ttattaactg acaaaggaga gaatattttg aacactttga ttgcaaaaga
    37981 cgtttttaga ttgcccgaaa tgaatgcaag attgttgtcg acctctgctc ttttattagc
    38041 ccttgatgtc atcttataca agatagcgat tggtcctgct tattttcaaa tcacattcgg
    38101 atttttaagt atggcgctta tgggttatct atatggaccg atctgggctg gtttgcttga
    38161 aatgttgtcg aacactttaa atttcacgat atttggttca ggaacgtttc aagctgcttt
    38221 tcttatcacg gctttccttg gtggatttat taatggctta tttttatatc ataaaaagat
    38281 aaacctgcct tccgtcatcg ctgcccaatt attgattatg atcccagtca gcctttttat
    38341 caattcttgg ctgatgtctg ttttgtttgg tgcagatttc aaagtaattt ttctaggtag
    38401 attcatcagg aatatgatcc aaatccctat tcaaataatg gttgtttatt catttatcaa
    38461 aactttagag gctagaaaag tgtttaaacg agctgtttga ttttacgtac taaggtagta
    38521 aactgatttt ggattaaaca ataaagcgtg cagtctcaac agactgcacg ctttattgtt
    38581 tctcactgga tccattttat ttcatcaagt ggataataga caaatcttgc tttacctaga
    38641 atatcagttt tattgatcgt gccaaacgaa cgactatctt ttgaaactct tcgattatct
    38701 ccaagtacaa aataattatc ttccggaagc ttggattgtc ccgttagctc ttgtagtgta
    38761 aagtccgtcg tataggatgc atttgcatga tctgatttca ggtttttagt tagataaggt
    38821 tccttaacta ctttcccatt gatcttcaat tgatcatttt ggtagctgac attttctcct
    38881 ggaagaccga ttactcgttt gatataaatc gtgccatctg ctaattgaaa aacaacaata
    38941 tcaaatcgtc tgatctccga aaatttttcc atcacaacca tatcaccttg cttcaacacg
    39001 ttttccattg aattgccttc cactggtacc gggatgaata aaaatccccg caacatgaac
    39061 gcaaggaata cagaaacaag taagtatttg aatacaagcc agaagcgatt aatatagcgt
    39121 tgtttttttg tcaatctcta tcaatccatc cctctttttt tcattctttc tttattataa
    39181 gaaaaatatc aaaaaaatgc gactagatag ctgaaataaa aataattctt tcaattaggc
    39241 tattggacaa aaaacttttt tgatcataaa gtacaaaact atctcttata tgtcatgatt
    39301 attttctaaa tatttttccc atgcttcgtc aaagatatcc atggacggca aatagtcgac
    39361 attcagttcc agataattag aaatttcttc gtagctagag ctgtgcttag gaaattggat
    39421 gtctttaccg gcttctgtag cgaaaacaga taaagcatca tgtgtgccac cgcctcgcag
    39481 tgtcattaaa taatgaaaaa agcttcgatt cacccttcgt tcctccaatt ttcttcgata
    39541 aaggcagccc ggcgtgcatg gtttctttta aaattttcag gatgcttttt ataatactct
    39601 tgatggtctt cttctgctag ataaaatggt tgggctggtt cgatttttgt aacgattggc
    39661 tgttcgaaac gtccactttc agctaactgt ttcttacttt tttcagcaat gatccgctgt
    39721 tcttctgtca aataaaagat caccgggcga taattgtcac cgcgatcctc gaattgtccg
    39781 aaagcgtcag ttggatcagt ttgctgccag taaagttcta ctaattgttc atatgaaatc
    39841 aatgttggat catagataat ctccactgct tctgtatgtc cagtcgtttg gctttttact
    39901 tgttcataag tcggatctgg tacatgccct ccagtatatc ctgacatcac tgtatggata
    39961 ccaggaagcg tgtcgaaagg ctggatcata caccagaagc agcctcctgc aaatattgct
    40021 cgttccatta tgattccccc tctaatacta ctcatccgat gattttttat tttcttttgt
    40081 cttgctttca gtactgctgg tgctagtttt gttggtattt gagttgtttg aagcatcaga
    40141 ggtatctttt ggcaaatata gactaaaccg aatgtcatca tttactaagt cgattttatc
    40201 tgctttaata tacatcccgt tttgcattcg gaattgatcc aacctaagca tgatagtcag
    40261 atcatctgta ttgacttcga tccaatctgg taatttatag tttctcttga tcatattcat
    40321 cacatctttg attggcaaac tcaatgttcc gatagaaaga cttctagctt ttagttggac
    40381 atttccgttt tccatcacat acggatcaaa atataaatag aaatcgatag gaaaacctag
    40441 tacttcgaaa gtaccattga gtagtgcttc attttccaaa taaaatttat attcaatatc
    40501 actatctttt tgatactcac taaggaaaaa gctgatgatt tgattgactt tttctttatt
    40561 tgaattgatc gttaagacag gatctccttg tctttccgta agagctggta tttctgggag
    40621 ttctggttcc cgattagcaa aaatacggct gcctaaaaat acggtcgaac caagtactac
    40681 cccaagaagg ataaggaagg cgaatttcca gtaatttgtt ttctttgttt tgtttgaaga
    40741 tacgtcagat cttgttttca tgtttattga tcatcctcct tctctaacca ttggttttgt
    40801 gtctcgatca gctgatctct cactgcattt gccatcaatt gataacctaa attatttgga
    40861 tggaaatgat cttcttcata gagcacatta tttttgatgc catttagatt ttctgtcgtg
    40921 ctagttgttt gatctgttcc ttcttctgtg acacctactt cctgattcaa tccttgataa
    40981 agcaaatcat tgattgggat aaagtagcag ttcggcattt tttttgtcac cgtttctgtt
    41041 cctttgttcc aattgttaac aattgtctgc atgtcagtga tctcaggaaa gttcaaataa
    41101 aatggattgt agatgcctaa aatgtaaata ggtgcggttt tattgaggga tcgaaattct
    41161 tccaatagtt ctgtgacatt ttcctgatag tttttcagtg gctttttaaa ggaattgacc
    41221 gttaacccga ataaattatt ttggataact ttcatcaaat cattaccgcc aacagtcagt
    41281 gtgataaaat cagctgtttt gatattgttt cgaatttctt cttttgtttt tactcgcttt
    41341 aagatctggt cacttcgttc accatttaca ccatagtttt ctgtttcaac cgcggtcaaa
    41401 ttataacggt cttttagatc atttgcgaca aggggaacga atcctccttg cttggtttga
    41461 tctcctactc cttcagtcag cgaatctccg atagctatgt agtgaagttt ttctttttta
    41521 tttggatctt ctctcacagt agttactggt ttcattagtg ggccagcttt cggtatagaa
    41581 gcagctaaac ctgcatagat gatgatcgca attaataatg ggaacaaaac gaggatcaaa
    41641 tgtcgtttcg ttaatttcat tttttcacct cttgtattcg attggttcta atgttatcaa
    41701 aaattttatc aaaaaggtag tctttatgaa aaaagaaaac aattattttc ctaattttat
    41761 aaagaaaaag agaataagct gcaagccttt caggctgagg gcttatcctc ttttcgacta
    41821 atctacataa tacatgattg caaacgcgtc tttaccagta tgcgtagcga taaccggatt
    41881 cgtatgcagt acagggatat gcatgtccgg gaataattct tgcaaaccct ctttgaattc
    41941 ttgcgccaat tcttttgcat ccgcatgtga aataccgatt tgtcgcacat ttggcaattc
    42001 tttcagttca tttttcaaat tattaaacca tttatcgaac gttttctttc ctcgcccctt
    42061 agttacaggg attaattcag aatgggcgaa attcatcacc acgcgtatgt tcaaaacact
    42121 agacagcaaa ccagttgttc ggctgattct tccacctttt accaagttat ctagtgtgga
    42181 tattccgatg tataattttg tattgtcttg tacttttttg acttcttcaa ggattttctc
    42241 tactgtttta ccttcttttg ctaattcagc tgctcgaatt acctgaaaag ataatccttg
    42301 gtcagtggta tcactgtcga taaccgttac tttcgttttt gttagattac tggcttgtct
    42361 tgctgcttct actgttccac tcaagccttt tgtcatatgg atcgaaatca cttcactgcc
    42421 gtcttctcct agctcatcat acatcgagat gaattctcca attggtggtt ggcttgtttt
    42481 gggcagattt tttgctttcg ccatcatttc cataaatctt tcgccgtcta gttggtcatc
    42541 atcgggatat actgttccgt cgatcatgat ggatagcggc atgacacgaa tgcctaaagc
    42601 atcgcgtaca tttttttcca tcgtacatga agaatctgtt acgattttta catttgtcat
    42661 tattttctct ctctctttct ttaacaagat gccttattca tgttaaacta catgtaagac
    42721 aatttctatt tttagtataa cagacaaata atgatttttc attaattaca cctagtaaag
    42781 gagccgtttt catggaaaaa acgaaattta atcgaacgta tgaaatatta aatgaagtgt
    42841 ttaatgcagt cacccatgga attgggactg gattgagtat cgcgggacta gtggttcttt
    42901 tagtaaaagg tgcccacttg cattcctccc tccatattgt ctcttatgct atctatggat
    42961 cgatgatgat tcttttattt ttaacgtcta ctttgtttca ttcattgatt tttacaaaag
    43021 caaaaaaggt gttccaagta ttcgatcata gttcgatttt tcttttgatt gcaggaagtt
    43081 atactccttt ttgtttgctg agtatccgag gatggctagg ttggacttta tttgtattaa
    43141 tctggttgtt tgcgattctt ggcattatat ataaagcgtt gacgttgcat aaacgggaga
    43201 gagtatcaaa agtatctacg atcatctata tttttatggg gtggctctgt gtcgtggctg
    43261 ctgttcctct ttatcactct cttggaatga ctggtgttat tttgatggta gcaggcgggc
    43321 tttcttacac gataggcgca ttcttttata gcttgaattc tatccgctat atgcatgttg
    43381 tttggcattt gtttgttatg ttaggtgcag gttttatgta cttctctgtt ttattcttta
    43441 cttaataaaa aaaataaagc tatggatggg acagctctaa ataacagcta gtctatccat
    43501 agctttttta tatcgtcaat tcgcctgtcc cgctttttac aggattctca ttacgctgat
    43561 acgtttcaaa ttgatgcgga taacgatttt tttcatccat ttctccttga ctagtattga
    43621 tcagtgacca atcagaccag tcaacaggtg gaaaataagc atctccatcg aatacatgat
    43681 ggatgactgt acggtataat atcgtacaaa atggcagaaa ttcttgataa acagctgacc
    43741 ctccagcgat gaaaaagata ccgtctgttt ctttttccag agcaagcacg tcttccacac
    43801 tatgcatgac atgcacgcct tctgctttat aggaagaatc tctcgtcaaa acaatcgtct
    43861 gacgattcgg caacggacgg ctacccatcc cttcgaatgt ttttcgtccc atcactagtg
    43921 tatttgcttc tgtcatttgt ttgaagaatt tcagatcatt tggcaaacgc caaggaagac
    43981 ggtcttcttt tccaatcaat ccgttttcat cctgtgccca aattgcagct aacattttct
    44041 catcctttct gattctaaac agcgatagga gctttgatcg ccggatgtgg gtcatatcct
    44101 tctaattgga tatcttccat ctcaaaatca aatactgact gcttttcctg attcaaaact
    44161 aaagtcggaa atgcgcgtat ttctcggctc aattgttctt tcatttgttc gatatgattg
    44221 atataaagat gagcatctcc taatgtgtga acaaattcgc caaccgctaa acctgtttca
    44281 tgtgcaatta ggtgagtcag caacgcataa cttgcaatgt tgaacggaac gcctagaaac
    44341 acatccccac tgcgttgata caattggcag cttagccgtc cctcttgaac ataaaattga
    44401 aacatcgtat gacaaggagg caaagccatg ctaggaacat cttccggatt ccatgcagaa
    44461 acgatcaatc ttctagaatc aggagtcttt ttgattgctt cgatcacttg tttgatttga
    44521 tcgataaagc caccgtcttt tgtttcccag tgacgccatt gatagccgta gatgtgtcca
    44581 agatcgccgt atgtttcagc aaaggaatca tcggttagga tcttctcgca aaaaagcttg
    44641 ctctgctttt tatattcttc attgaattca ggatctgtca aacatctatg gccaaaatca
    44701 gtcatatctg gtccattata gtctggactt ttgatgtagc gttcaaatgc ccattcatcc
    44761 caaatatggt ttttattttg taatagatag cggatattcg tatctccttt taaaaaccaa
    44821 agcaattcgc ttttgatcaa tccaaaaggt actcgtttcg ttgttaacaa aggaaaccct
    44881 ttttgcagat caaaccgcat ttggtatccg aataagctta atgtgcctgt gcctgttctg
    44941 tcttctttac gatgcccttc ttccaacaat tttcttccta agtcaagata cgcttgttcc
    45001 atcctttttc ctcctaatct tctacccatt cactcaagta ttcccaccgt gccatttttt
    45061 cttcaagttg tgcttctgtt tcagatacgt cgttttgcaa ttcttgtaat cgagtgaaat
    45121 tatctccttg atgattcatc tcttcttgga gcaatgagat tttttcttca agttctgcaa
    45181 tctcatcttc aatcgtttcc cattcttttt gttccatgta agataatttc ttcttttcag
    45241 caggttcctt gctctgtatt tttggtttcg ctttttcagc aggctgctgg gtctcttttt
    45301 gcttcagtaa ataactggac atgtttccgt aataaagttc ttgttttccg tttccttgga
    45361 atactaataa cttatctgct accttgtcca agaaataacg gtcatgggaa acagtgatca
    45421 cagcacctgg aaaacttcta aaataatctt ccaaaatcgt caatgttgct atgtccaaat
    45481 cattggtcgg ttcatccaat aataaaacat taggttgctg aatcagcagt ttcaacaaaa
    45541 ataaccggcg tttttctccg cctgaaagtt tgcctatcag tgtcccatgc ataaatcttg
    45601 gaaataaaaa tcgttcaagt aattctgcta ctccgatttg actgccatct gctgtttttg
    45661 cttcttcagc agcttcttgt aagtaagcaa tcatccgttt atctggtgcc atttcttcat
    45721 tttcttgtgt ataatacgca agatgaaccg tttcaccgat agacattgta ccgctatcca
    45781 ggggaattct gccagctaga atattaagca atgtcgattt tcccgcacca tttttaccag
    45841 taatacctag tctttcccga gattgaatca ataaatctaa atgttctagc agtgtttggt
    45901 catttatacg gtaactgcca tctttgattt ccagtacttt tttccctaaa cgttgtgtcg
    45961 ctaggttcag ctctaaatca tcttcttggt ttacttggta caagttctcc tttagatctt
    46021 cgaaacggtt gatccgtgct tgctgcttgg tgccacgtgc ctgtacgcca gccctcatcc
    46081 aagctaattc ctgtttataa agccgcttgc gcttttcttc ttgttctact tctacacgat
    46141 cacgttctgc tttttctaag acgtaagctt cataatttcc tttatactcg tataattttc
    46201 caaatgaaag ttcgaagatt cggtttgcta ctctatctag aaaataacga tcgtgggtaa
    46261 ccatcaatag tgcgccacgg tattgtttca aatagttttc caaccactcg atcgcttcat
    46321 aatctaaatg gtttgttggt tcgtctagta atagtaaatc gggttcatca atcaacactt
    46381 gcgccagact aactcgtttt ttctgaccac ctgataaagt actgattttt ttatctaatt
    46441 cactgattcc taatttttgc aaaataatct ttgcgttggt atctgtagtc caagcatctt
    46501 ctttattcat ttgttcttct gctttagcat aacgtttttg cacatcaggg tcttctccgt
    46561 tttcccctag ttcgatcaat gcttcctcat atgctcgaac agtttggatc aaggggctgt
    46621 ttccttgaaa gactgcttgg agaacagtta attcatcgga aaattcagct gcttgagaaa
    46681 gataaccaat acggtaatca gttggataaa acactgtttg ccgatcaccg tcgctgctat
    46741 cgataccggc aataatattt aagagacttg ttttacccgt cccgttcgtc ccaatcaacc
    46801 cgatacggtc tttttcgtgg accaaaaaag aaatctggtc aaacaaatct ttttcaccat
    46861 aagttttttt gaggtcagtt acttttaatt ctttcaacat gttccctcct tatcttggat
    46921 attgtatcat aaaaatagtg aacttcagga aaattttttt ggtatttgtt ctttttgtgt
    46981 tctcaaaaaa agaacaggac cgattcgatc ctgttctgat atgttttgtt ttttataaaa
    47041 cttgaaaatt tttacctttt tattttattg gactcgtttt ttttgacttt gctcgaaacg
    47101 caaatcggaa agaaaagtta tcagatggtt tgttcatcgt ataagattct aacaaattga
    47161 tattcctgcg atagctgttc gcagaaaacg tcgtgatttt ttcagcaact tcgtattcat
    47221 caatgatttt tctttcaaga taataacctc ttagcatttt tttcgtaaac agactatctt
    47281 gctggatcat ccacgaagaa atcaaattcc ccgagttcat ttttattcct tcaagtttgc
    47341 gttgctggat aaaaaattga accatcgttt catcataaat atcagtcaag ttatctaaac
    47401 tttcaataat caactgagta tttttttgat atgtctctct gatttcttgg atatcttcat
    47461 cactaataaa tgtctgacga tcagcatatc ttctttgcca aaacattttc ggatggagaa
    47521 cgattcgcat taacctacgg acaacaatga accaaaagcc gataaaagac aaaatctggc
    47581 ttgtgataga atgttcgaat cgagaaagaa aacgggagta aaaacgataa ccattagaag
    47641 aaagcttgcc cgaacgataa ctttcatcca atccatcccg ttcgatcgac aaaatcagtg
    47701 cttgtatttc ttgtacttct tgcttttcat catcggttaa atcttccaag tacagatcac
    47761 gtatccgttc ttgataattt tctatcactg cttcagtggc taaaaattct tttgtattac
    47821 gatcaatttc ctttatttct tttcgcaaaa cttcaacgac ctcttctaaa atcatcaaag
    47881 cattcaaatc cgtgcttttc gcttcctctg tttccgtcag cataggcaag acaatgatcc
    47941 ctatgaccaa agtcactaag atgacacccg ccgtcagaaa caaaagcaaa gaccgctggt
    48001 aaaacatcat attattgatt gaaaatggca aaataaaaat cgtagccaaa ctgactgttc
    48061 cctttacacc gccaaatgtt aagatcaaga tctcgttcaa ctgttttttg aactttttac
    48121 tgccatcttt gaatacataa aaaagactga tagaaatgaa tctgatcaca aaaagcatga
    48181 cagagattaa tacgataatc gctaataaaa gaccgtttgg atataaaccg tctccccata
    48241 ctggcgagaa cacttgcgtc aattcgattc ctaaaaatat aaatactaat gcattcagtg
    48301 taaaagcaat agttgtccat gtactgtggg acaagctcga caattctgca tcaaacacag
    48361 agattttcct aaaaccagaa gcttggagaa tacctgctgc cactgcagca atgattccag
    48421 atacatcaaa tgcctctgcc aatacatagg ctagaaaagg aagcaaaagt tcgatcagca
    48481 gataccctgt gacatcttgt gctgatgctt tttcgatcaa atgaattatt ttttgtttga
    48541 accagacaag caaaaagccg atcaaagctc ccccaatact agaaactact agactcatcc
    48601 ccgcgtttac tgctgaaaaa gatccggtga tcagcgcacc aagagcaaac tggaaggcag
    48661 taacaccaga tgcatcattc aaaagacctt ctccttccaa aatatgcatc gcctttttag
    48721 ggatattcac tcgtccagaa agagaactga ctgctaccgc atctgtcgga cctaacgctg
    48781 ctccaaaagc aaagcaggca gcaagtggga cacttggcaa caggaatgat aacgtcgcac
    48841 ctaccccgac aagggtcaaa atgactcctc caaatgccaa gaacaaaatt gtcccgaaat
    48901 ttttgagaat cgaagaaata tctgcttttt ctccttctct aaataacaat ggtgcaataa
    48961 tcataactaa gaacaattca ggttcaaaat cgattgattg tccccactct gtcagaccta
    49021 ataccactcc aaggaaaatt tggatcagtg gagctggaat cattggcaaa atgcggctag
    49081 ctatgttcga taaggtgatc gttactgcaa atacaataac taactcagca aattccatcg
    49141 tccatcccct ttatttttta ttttgtgtaa gcatttttaa aaattgttct tttttcttta
    49201 aaattttggt ttcgactact tcaacctgtg tttggttccc ctctaattca cactgtacac
    49261 gttttgactc caaacgaagc agatcatgtt tcagacgttc caactgacga tacatcaata
    49321 tatttctttt acgcaactta caaagtattt gacggcggtc atccatcgaa agggcgccat
    49381 agcgatcatg caacagtttt ttttgttgtt caaaactctc tctcattttc cagatctcct
    49441 atacacaaac ttccatcatt atagcaaagt tctttttgga tgaaaaatat ttcattgttt
    49501 catcgtttat tgctagttag aaatttccat aaatttttca acgcctcatt ctattccaaa
    49561 tagtatcaga tatcaagtaa aacttaagaa agataaaagt ttctgacaaa aggatgttta
    49621 ctttcccatt cctgcctttc ttgttctttt atcacaacaa aaaaatgggg ctgcgacaaa
    49681 aatcttgtca cagtccctta ttctgaataa acggtgtgga agagacagcc tatcagtagt
    49741 aataagacac atctctttca cagcctcatt tttgcgtaaa aatcgattta ttcgaaaaat
    49801 tccccgtata catcttctac acgttgatct ggattgatca cgatatacaa gttacctgtt
    49861 ttttcgctga tttttgttga ttgatattga ttgtctaatc cttctgttcc tttatctaga
    49921 tatgggaagt acacaagatc aggtgtgcca tttcggtaaa ggatttccat tcgctcgata
    49981 tcttcgtatt tcaatgcgcg attaaacatg cccatttcca gtccgcctag gttgatatca
    50041 tgtgtcgcaa ctgcgtcccc ttcatggaag atttcgattt taaatccagc acacggatgg
    50101 atttcaacaa attcactgcc attgattcgt ccaaaacttg ttgtgatttg tttgatccaa
    50161 agatcgccga tatgacggcg gttgatcgtc caggtttctc catttctaaa ataaaatttt
    50221 agcgctgtca tttctttact cattaaaaag actcctttat gatgtaattt attcttgtac
    50281 tacctcagtt tagcacaaat ttatgtaagt ggtcacatct tatgtttttt cttctaatga
    50341 cgtatctgcc cactttaagt agccaacaaa gctgagcaga tacagtctag tgttttttaa
    50401 atcaattttt ctttcgataa aaaatccaaa acctgttttt tatcattttt tattctttgt
    50461 tctacgacgg ctttttcagc taattgcaaa gcttcactaa cccacttacc aggttttttt
    50521 ccagtttctt ctagcaagat tttaccatct actgctaatt cgcttaatga cttgataggt
    50581 aaacgatcat aggattctcc tacggcatcc atctgaggtg tttcgtcaaa atagatcatc
    50641 aattcttcta cttgcagtgc atgttttttg cctaagaagt acaattcgaa tggttccaaa
    50701 gctccagttt ctcgttgtcg tagtccttgg acaagtgctt gaacgtcttt aatcatttgg
    50761 ttagaacact tccacgattt caaaaaggaa cgaatctcat tttcttttag atccagttgg
    50821 ctgatcaata atgcccatgc ttggctctct tctttcaatg ggacggatgg taattcagca
    50881 aaacgtaaaa gtgcttcgcc ttcttctttc aaaccgggac agcaaatgta gcactctgtt
    50941 tcaataaatg catggattcc cgcggcccgt tcatttccca agagcatctt gatgaattcc
    51001 acatttatac gttctacaga tattttacct aatagctcgt ggttttcttt gatggcgtag
    51061 aaggtttctt cctctaattt gaaccctagt tgactgacaa aacgcaaccc gcgcatcatt
    51121 cgtaaggcat cttcatggaa ccgctcatga ggattgccta cagctcgcaa gatctgttct
    51181 tctagatctt gcagaccatc gaacaaatcg atgatttctc catcttcttt caaagcaaac
    51241 gcattgatcg taaaatctct tcttttcaaa tcttctacca acgaacgaac gaattcgaca
    51301 tgatctggtc tacggtagtc ctgataagtt gattccgtcc gaaatgtggt gatctcatat
    51361 tgttcatcat tttctaatac caacacagtt ccatgttcga tcccaatatc tatcgttttt
    51421 ggaaaaagct gtttgatttc ttctggaaat gcgcttgttg cgatatccac atcatggatt
    51481 ggctggttca gcaagatatc acgaacactt ccacctacaa aataagcttc atatcctgca
    51541 ttctctaatt ttttcagaac tggaattgcc ttttggtatt ccagaggtaa ttgttttaat
    51601 ttcatttttc caacctttcc tgcgtgtttc ttgtcctgag ataaagactc agttgcatgg
    51661 tgactgtttg acaagtccgt ttcagagtct tcaaggccag gaccacttca tcttgtttac
    51721 tcgtccttac gctcaaagcg attatggtct ctttgattga atttttccat gtttttttca
    51781 aaaacttcag ttaagtcgat attcaatgaa ttagccatga tcatcgtaac gaataaaaca
    51841 tcaccaagtt cttctgctac cgagttaact ggttcagaag cctttttgct tttttctcca
    51901 taagtgtggt tgacttctct tgccaattca cctacttctt cagttaatcg agccatctga
    51961 gctaatggag agaaataccc caccttgaat tgctggatat attcatccac ttcctgctgc
    52021 atactgtata aagaacgctt tttatccatc tttttccctc caaaactatc ttaccaaaac
    52081 tttaacgcaa atcctagata agagcaattg agaaaatcga atttccatgc tacatttagg
    52141 aaggaatttc taaatggaaa ttctgtgaaa atacataatt gaaagctgga attcatatgg
    52201 tcaaacgaaa aacagtaaaa gaagttcttt ttatcattat aggaacaagt atttatgcat
    52261 ttggtcttgt ttacttgaac atcgctaatc atttagcaga agggggagtc tcagggatca
    52321 ccttgatctt aagagcttta tttggtattg atccagctta tacgacttta ttaatcaaca
    52381 tcccattgat tttactagga ggaaagatcc tcggtaaacg ttccttggcc tatactgttc
    52441 taggtacact ttctttgtca ttctttttat ggatctggca aagggttcca ctagaaatca
    52501 atttacagca tgatctactg atcgtttctc tacttgcggg tttagttgca ggtgtaggaa
    52561 gcgggatcgt ctaccgcatg ggtggaacaa caggcggcag tgatattatc gctcggattt
    52621 tagaacaaaa ttacggcatc actatggggc gttccctatt ggcatttgat atcatcgtct
    52681 tacttgcttc attaacctat atcgacttga aacgtatgat gtatacgttg attgtttcgt
    52741 atgttttcag tcgtgtgatt gattcgatct tagatggcgg atattctgca aaaggtctac
    52801 ttgtcgtctc caacaaaagc gaagagattg caccactact gatgaccggt ctgcaaagag
    52861 gtgtgacttt cctttctgga gaaggcgcat tctctggtaa ttcaaaaaaa atcatctata
    52921 tggtcgttag ctctagtgaa ttaactgaag ctaagaggat cgtccacgag attgacgaaa
    52981 aagctttcct ttcaatcatc aatgtgcatg aagtggaagg gcaaggcttt acttatttga
    53041 agccacagac aagattactg aaaaaactat aagaaaaaag acaaagatag gctatgagga
    53101 aagattccac atccagctga cctttgtctt ttttagtact atactatttt taactaattg
    53161 ttatgttcac ttacccggtt acttttcttt tgtgtctgca aaaggatctt tcggttaact
    53221 tcatcagata atttcaaaaa agcatcccta tctccatctt ctagtgcttg atcgatttga
    53281 gcataaagca tttttagttt tgcctcttct tctttttctt gaaaatatcg ttcaattaat
    53341 tcagtatctt cttcactgac tgaagaatcc caagaagaaa atggattgtc ttctaagata
    53401 gatagatatt ctcttgtctg ccaagcattt tcgaatatac attccacata taaaggcttt
    53461 ttccaattca aacggatttc atgaaaaatc tggtctgtgt ccgtaaattc ttttccctgc
    53521 aaaaacaatt tcatgggttc cccttcaaca gatagatcac tgatctgcag tcctcgatcc
    53581 gcaaaattcg ccccttcaac aaagtggaca ttgcttaaaa tcgcttcatg attggcaaga
    53641 taattcaaga tccaaaaaac ttctcttcgg ctaaaagata catgattgac catccacgtt
    53701 aaaaaattct tcttttcccg tacatcaatt agcatttttc tcacctctct gttaggtcat
    53761 ctaataatga cagtgcctcc atatctcctg gttcaagtgt taaataataa gtcaataatt
    53821 cttgcgctct tttcagctgc ccttcttctc ttaagaaaaa ggcatactct ttcaagaaat
    53881 ctggttcatg tgatagttca tgataagcct gttcatagtg tacagctgca acggtaaagt
    53941 cttctaattc attataagca tgggctaggt tccattctgc ataaggatta gcagtttctt
    54001 ccatctgatt gatcacttgt atcacatctt catatctttc atcatccaag taaagattac
    54061 ttaaagtaag taatgtttca tcttgtttgt ctcctacttc taaagctttc agtaaaagtt
    54121 cttctgctcg ctgtctatca tgcagacgga aagcattttc cgaggccagg tgataaagtt
    54181 cgacttggta aggattttct ttgattcctt cttctaacac tgtttgtgct tcttcaatca
    54241 tttcttcttc ttgaagagct tgtcctagat atagatataa cgattgataa tgcggattaa
    54301 cttctcgaag ttcttccaga tagttgattg cctgctgatt ttctttcaat tgaagattcg
    54361 taaaagctag ctggaacagt cgatcatctg tcctttcttc tttcagtgct tcttctaaag
    54421 gtacgatagc tgcttcgaat tctccttgca tacttaagga ttgtcctaaa cgttcctgca
    54481 tcgagattcc tgaaatttca tttatcccgc ttgccaacaa tgtttcataa accactgctg
    54541 cctctttgaa acgatcaact gaaaaataca attcagctag cgcaaactgg atcaatggtt
    54601 catcaggaag caacccagct gcttctttca attttgcttc actcacttca gggattccga
    54661 taacttggta caaatcagct atcgccaata agctttgcgg atagtaatca ctttgcttat
    54721 ccactttttc caggtattca aaagctaagt cgatctcatt atcttcgatt gcaatttctg
    54781 ctaacgggat gttcagtccg tcattttctg ggtattggtt gatcagttgt tcaaaaatct
    54841 gttttgcttc gatcaaaaag ccaatagcca gcaattcttc gcctagttca gctaatatat
    54901 ctgctgggtc ttcttttaat gctttttcta aaaagatttg tgcttgtgac aagtcttcat
    54961 ctgataaagc ttgcaacatt ttttcgctat ttgtattcat ttcaattccc tcttatctca
    55021 ctgacgattt gttgaaatac cgtcattgtt ctcaataatt ctttttcgtt tggatgttgg
    55081 tatccgtcta ttatacctat tttttctaaa acaagtattt ttttgctttt ttctgccaaa
    55141 aaaagaactt tttccaaata ctccatcttt gaaatctgtt ccagccagtg gattggatag
    55201 ccaagcaagt ccagccacac aaaaaagttt tttagttgga aatcaaaagg atatgcttgg
    55261 agattccaca cgaaatgaaa catcattcct aaaaattttt tcatactagc agaaagtaga
    55321 tggccatttt cggtcagata aaaagcttgt tcaaacagtt taccataatt tgacaggttt
    55381 tctgcctcta attgataaaa atagatcatt tcttcgatca tcccggcaaa cggccgagtc
    55441 gttaattgct ttttatttgg atagttttta tacagatttt gcaaaaaacg atgatcacaa
    55501 atcattccgc aacagataaa agtcaaaaag tcaatctgct ttccgtccac ctgccgctcg
    55561 ctgattgttt gatcataaac gatgcgttct ggcagattga tggtttgcag cactacacga
    55621 tttggtagct gcaaaatcgt ccgctgcggt gttaatgctc ggcttagaga acggatcgat
    55681 acagggatca tccatagtga tgaatcaagg gttgtatgtt tttgaaaaaa acctgccaga
    55741 tccatgatcc cttcatttcc aaatccgatg ataaacatgg attgattttc gggatagcgt
    55801 ttgacgaaat caagcaggtt ctttaattct gttaaatgat tgcattgagt gttggcacaa
    55861 atataccagt cattgtttgc ttgatttgca aataacgggt tgatcttatc tgcaaacaaa
    55921 tcataatagc gctgattcgt taaaaataag attggctgat caatggaaag ttctcttagc
    55981 tgactgacta gcgtttctcc gtaaaacact ttcgtcaacg catcttctac ttgataatca
    56041 agttccatac gcatccctcc tcttcttatt tttattttac cattagtaag caaattctag
    56101 aaaagataag agcaaagctc acctcataac ttgcaaataa ataaaaatta aataaaatac
    56161 atgtgttttc tatgtatgac atacggattc ggaatctctg tctcttattt attccttttc
    56221 tgctaggaaa taaaaagaaa agcacttgta gccctagagc cacaagcgct ttttcaactg
    56281 tcttatttaa cagcgtcttt taatgcttta cctggtttga atgcaggtac tttgctagct
    56341 ggaatttcga tttcttcacc agtttgtggg ttacgacctt tgcgagctgc gcgttcgcga
    56401 acttcaaagt taccaaaacc gattaattga actttttcgc cgttagctaa agcatcttga
    56461 atagttgaaa atacagcatc tactgctgca gttgcatctt ttttagttaa atcagtagct
    56521 gaagcaactt tttcgattaa ttctgctttg tttgccatgg atagattcac ctcctccaca
    56581 agagatatga tagaaatatc atttagttaa aactttctga gtggtccaga agtttaaaaa
    56641 gaaatattga ttaacttcaa tattctgtta tcacgatatc atatgaaccg cttaatagca
    56701 aggtttttac caattttcac atgctttttt tagtcataga aacgtaacaa acgaaactgt
    56761 ctttttcttt tgaaaaaaaa acgtcgatat ggtaaaatgc ctattttctc ctacgaggga
    56821 taattcggat ggacgtccct tcaaaagtaa atgcttttct gatttgattt tctaagaaac
    56881 gttcataaga aaaatgcatc aattcctctt cattgacaaa aacgacaaat gtaggtggtt
    56941 tgacagcgac ttgtgtagca taaaaaatct tcaggcgttt tcctttatct gttggtgttg
    57001 gattgattgc tacagcatcc ataatgatat cattcaacac agccgaagag atacgaagat
    57061 tctggttcat acttacttgt tcgatcattt caggcagacg ttccaaccgt tgtttagtca
    57121 ctgcagaaac aaaaacgatt ggagcgtaat caagataccg gaattcatca cgaatctctt
    57181 gttcgaaatc acgcattgta ttggtttctt tctttacaag atcccattta ttcacgacga
    57241 taataattcc acgaccagct tcatgggcgt aacccgctac tcgcttgtct tgttcccgaa
    57301 tcccttcttc agcattcagt accatcaaaa cgatatcaga acggtcaatg gcacgcattg
    57361 cacgcatcac gctgtatttt tcagtatttt cgtatacttt tccgcgttta cgcataccag
    57421 ctgtatctat cattaagaat ttctgaccac tttcagaaac gaagtgggtg tcgattgcgt
    57481 ctcgggtcgt tccttcaata tccgaaacaa ttacacgttc ttctcctaaa atcgcattga
    57541 tcaaagagga tttaccaaca tttgggcgac caatcaaact aaacttaatc gtgtcgtcgt
    57601 cctcttcttc agtctcttca gagaaatact tcactgcttc atctaaaata tcaccaatcc
    57661 ctagtccatg gcttcctgaa acaggataag gatcgcctag ccctaaggaa taaaattcat
    57721 agatatcgtt tctcatttct ggattatcta ctttattgac tgctaaaatc actggtttat
    57781 tacttctgta taaaattttc gcaaccatct catctgcgtc tgtcacgcct tcgcgtccgc
    57841 tgactacaca aatgattaca tctgcttctt caatcgcgat ttctgcttga tgcttgatct
    57901 gatccataaa aggttcatcg ccaagatcaa ttccgcctgt gtcgatcacg ctgaattctc
    57961 gacctaacca ttcacctttt gcataaatac gatcacgagt tactccagga gtatcttcga
    58021 caatcgagat acgctcacca gcgatgcggt taaaaatcgt agacttaccg acgttcgggc
    58081 ggccaacgat tgcaattgtt ggatttgcca tattatttcc tcctcacaag tttccaatct
    58141 cacttagttt aacgaatgca ttgccaactt tcaagcatag attgtcaatt aaacgaagta
    58201 tttttattcc ttattgaaat actaatcgct tttcaaaaga aaaactgaga caaaagcagc
    58261 tgctttcatc tcagtcacag atacaaaatc aattattttt cagaatcatc ggttgctttt
    58321 tcttctactt cttctttcaa cgcatcacct aaaatgtctc ccatagtaaa tccagtattt
    58381 tcttctggta attcataaga ctcaacattt tttggttctt cttctgaagc tggtttttct
    58441 tctaaagctt tgatactcaa tgcaatacga tgttcttctg gatggatctc taatactttc
    58501 actttcactt cgtcaccttc atgaagcact tcatgtggtg tcgcaatatg tttatgtgaa
    58561 atttgagaga tatggactag cccttctact ccagggaaca cttcaacaaa ggcaccgaag
    58621 cttgtcaaac gtttaactgt tccgtctaat actgtgccaa ctggagcttt tgtatcgatt
    58681 tctgaccaag gtccaggctg tgtgtctttg attgacaagg aaacacgttc ttgttcagga
    58741 ttgatagaca acactttgac atttacatca tcattgacag ccaatacatc acttggtttt
    58801 gctacatgac tatgtgaaat ctctgagaca tggactagac cgtcaattcc gcctaggtcg
    58861 acaaatgcgc caaaatcagt aagacgtgca acacgtccac tgagaacatc tccctcatgg
    58921 atagttgaaa gaatttcttt tttcttttct tctctttcgt tttccactac cgctttatgc
    58981 gataagatca aacgattttc tgatggttcg atttcgatga ttttaaagct caatgttttg
    59041 cctttatagt ctgaaaagtc tgcaacaaaa tgatcttcca ccattgatgc agggacaaaa
    59101 ccacgtacac cgacgtcaac gactaaaccg cctttgacaa catttgtaac aggtgcttcg
    59161 atgaccttgc cctcttggaa atctctttcg atatcttccc aaactttttt agcatctaaa
    59221 cggcgttttg aaagtagata gctgccgttt tctttatctt tgccgatcgt actgataacg
    59281 actaaatcta atacatcacc gacttttact acttcgctga tatcttctac cggcaaagtt
    59341 gataattctt ttgccggaac gactccttca actccagccc cttcgattcc gacaatcact
    59401 tgtttgtctt caatgactaa aacttcgccc ttaacaacat cgccaacttt tacttcttgt
    59461 acgcttttca ttgcgtcttc cattgactgg ttgttctctt gattttgatc aaattctgtc
    59521 ataacacttg tcctcctaac caacattctg ccgtaagtac ggtactgttt ttagtttaat
    59581 tgattattca aaaaaaataa agcgatttcg ttcgttttcc ttgaaaaaac aattgttttt
    59641 catttttttt cttaatttaa aaaagaagat aacctttttt caaaacaaca gcttttattg
    59701 ctgcaacgac ttctggaatc gatttgccag tcgtatcgat acgaacagca tcctctgctt
    59761 gcttcagcgg agagacgtcc cttgttgaat cataatggtc tctttcctgt atctctttcg
    59821 tcagtgtttc aagatcagtc ggaattcctt tttcttggtt ctctttgaaa cgtctttctg
    59881 cacgctcact tacgcttgct actaaaaaga ttttcacttc tgcattcggt aatacagctg
    59941 tcccgatgtc tcttccgtcc atgacaacgc caccgcgttc ccctattttt cgttggacag
    60001 caactaattc ttctctgact tttccatgtg cagagacttc agaaacagct tttgtgacat
    60061 ctggttgacg gatttctaaa gtcacatctt ttgatgctat gaatacatgc tgtccatctt
    60121 cttgttgcga aaaagagata ggatactttt tgatcagcga aactagccct tcttcatctg
    60181 aaaaagatac attgttcgta atagctaaat aagttactgc gcgatacatg gcaccggtat
    60241 ctgtataaat ataattcaat tcttttgcta atatcttggc aacggtactt ttcccagatg
    60301 aagcgggccc gtcgattgca atactgattt gtgtcatgat ataactcctt tttctcagaa
    60361 aaaaagccgc aaagcgcggc tattattatt taattcttaa ttcttgacca gggtaaagca
    60421 taaagttgtt tggatctaag ccattcaatt caaacaattg atcagtggtg atccctgcac
    60481 gctcagccac ttgttttgga ccttcgcctg cttgaacagt cgttgttgaa ccggctgcag
    60541 ctgatgaaga aggtgttgtt tctgctgcat tgctgcttga atcccctgct tgataagttg
    60601 cctcacttga ggaagtcggt gttgtctctg ctgcaatact gctttctgac gttacacctg
    60661 tatcttgaga cacagtagat tcttccgcga ttgtactaga ttctactgtt gaagtctcag
    60721 ttgactcctc ttttgttgta cttgtagaac tttctactac tgatgtcgaa gtttcagaag
    60781 aagttgctgc tgttgcattg ttgcttgatc catttctgat ccagaaataa gcacctgctg
    60841 gaatagcgat acataagacc agtaaaatca aaaatagcga aagaaataat gtatttcctt
    60901 tcttttgttg tctctgagaa cttcttgatg aaacttcatc atctgtatcg tagattggtt
    60961 gttcccatgg ttcttgtgtt tcgttatttt ctgtagattg atgtctatct tttctgctca
    61021 ctgttttacc tcctaaactc tatcgtgtgt attataccat aggaaaaagt gtcttgtcct
    61081 aaaaaatcaa tgttccatgt tttttttaaa taaatttagt aaaatcgttt cccaatgaag
    61141 ttgttcagtc ttagaaaaaa gcttcctctt tggcagaagt tctgcttttg ctccatcaat
    61201 atcacaacaa ttctgcggct tttcggagag tttttcgcca aaataagcta agatgaattt
    61261 tctgcggcag ttttcttcat taatatagcg aagcatctgc tgcaggcgga attctttttc
    61321 tttttcctga cgtttgagcc gttccaccca attttctggt ttttcagact gctggatcag
    61381 ctccatccat tttttttgca gctcatcaaa gggagcttgc tctgtggcat attccaaata
    61441 aagctcaaaa ctttgtcgct gttctctaga aagttgatta aagaaataat ggatacgttc
    61501 atccccactt tgataaaaaa gaattgctgc actttcttcc tgatctctgc ctgctcgacc
    61561 gatttcttgt acatagtttt ctagactgtc tggcaaatca taatggacca cataacggat
    61621 atcagattta tcgatcccca taccaaatgc attcgtagca atgagaaact gcagctgatt
    61681 ttttacaaac tgctgttgaa gttgtcttct ttgagctgca tcaagaccac cgtgatagta
    61741 tccaactgta aaacgttccc tgaataaatg atacaatcgt tcgacttctt tttttgttgc
    61801 acaataaatg attgccgctc cttgtgctct ttccatgaag tgttcaagtt cttgttcttt
    61861 ttgctgcgtt ttccgaacaa aaagcgagat attttgccga ttgactgatt gtctgatctc
    61921 ttttggtggt cgatcaaata gtacatgacg tatatctctt gctactaaat ctgttgctgt
    61981 cgccgttagt gccagtgtga ccgggtttcc taaaagcttt cggatttttc ctaactgttg
    62041 atattctgga cggaaatcaa ctccccattg agacacgcaa tgagcctcat ctactacata
    62101 taacgcaata ttttgttttt tcagatgctc taaaagagaa ggattagtca acatttcggg
    62161 actcaaaaac aaaaatttat attgcgatag atgacggagg acgtatcttc tttcagattg
    62221 cgaaagtaaa ctattgaaag cagctactcg tttctcccct cgtttttgta attgcgtcac
    62281 ttgatcttcc attagagaaa gcagcggtga cacgatgatg accagacctt ccattaaata
    62341 ccccgtcaat tgatagcaaa ggctttttcc cgttcctgta ggcaaaatag cgagagtatc
    62401 ttctccatca agcaacgcct gaataatttc ttcttggccg ggacgaaatg aatcaaatcc
    62461 aaaatatttt tttaattcat ttattaacat tctgtatcgc ttcctttctc aatagataga
    62521 tttgatacaa acgaaattct ccataatcta attgtccatc tacattccat tcgctaaagc
    62581 gccactctcg cacggaatcc ttatttggtt ccaaacgttc gattgtttct gcagagagaa
    62641 tccactcgta tggaaaatca tcaaaaaaca aggcccactc aataagatga tctgttactg
    62701 ttcctctttt taaatgacgg attgccatga tctggtcaat tgtctgacca ttcataaaca
    62761 tctgcttggt gatcatcatg ctttgattga aattttgctg taataatgaa tcgatcaaag
    62821 cgtgccaaag cgaatctggc cgtttttcga tttgtgctaa caaaaggtgg atacatctgc
    62881 tttgttgcag ataaaccgct gactcatcat tgttttttgc cagctgataa ggaagcagcc
    62941 ctgttcgctc atttccagat aattggttag ctaaaaaatc tgctgcttct tctggtatct
    63001 ccgaaaacag ctgcaccaaa ctctcatacg cagtatcaat caaaatttca cgtggcaatt
    63061 ggctttcact aagccatttt tttagttgga aagtataaaa aggacttgtc tctgctggaa
    63121 gatagtcttg aatacccgtt gccagattag aaattacttg aacagcaaat ttaatgagcc
    63181 gccaactagt ttcccctgtt ctgccatagc ggtcaaaacg caaaccagta tgttctattt
    63241 gatgttcgga caacatatca gcccctgcag gcgttagctt tgcttcattt tcatttattt
    63301 cgatccaacc ttgctgcgca attttttgca aaatttgata aaacttatcc tgcttcaatt
    63361 ctggaaaact gttatggata aacaaaagtt cgtgggtaaa tccataaata agtactgaag
    63421 tcgttcgttt tcccacaagg agttggtaaa gagaactaat ccgcagcttg tgtcctgatg
    63481 aaaatagcga taaaataaaa acaatcatat tattctcctt aagttaggat ggttagaaat
    63541 gtcactacta tgtaaacttg tacctgaacg ctgtattgca tgcggtcttt gtcaaatcga
    63601 agcgccagat attttcgatt atgatgaaga aggaatcgtt ttatttgccc aagaaccaga
    63661 ggctcatcaa cagttcgtga tgccggaaga agaaacatat gtaaaaaaag cgtatcaaaa
    63721 atgtccagtt cgagcgattt tattagaaaa taaaatataa atataaacga aactttaaaa
    63781 acgtacacta agttctctaa acttgaaaat aagccgggat ctgtttctct tgttccgtga
    63841 aatcccgact tattttgaaa gattcatttg ctatctatag ttaattgact agttttttca
    63901 cggaccctat aggacccatt tatattattt caactttttc agccagtttt ccaatgtatt
    63961 gacgatcaca gtttgctggt ctgcgttaga aatttctgcc tctccatctc ctttttgctc
    64021 accatagctg ccaaaacctc catgatttcc gccattgatt gatacatact ctgttctttc
    64081 cggtaaatac tgcttagctt cttgataagc ttcctgattc aatactttat cttttgtcgc
    64141 cgtgatcgat aaaacaggaa cagctgattc tgtcaatgtt ccttttttgt cgggataact
    64201 tgccatgaag aatacccctt ttaaatgttt gtctgaatga ttcttattga cataacgact
    64261 tgccattacg ccacctaatg aatggccacc gatcacataa tcggaatttg gaaaatcttc
    64321 tttgacctta tccgctttgt ttccgcccat cactgctaga tcaagtggca ttttgacaat
    64381 agcgactgaa aagccgtttt ttgctaaatc ttgcgcccaa atactataac tttctggctc
    64441 tacgagagca ccaggataaa aaataagtaa tggagacttt ccatgattct ttttctctcc
    64501 ttcaaaaaat aagtaatctt ctttgttttt tccttctttt accaacactt gcgcttctga
    64561 cgatggttcg tacgtatttt gctgtatata gtaataaccg gctccaccga gtaatcctaa
    64621 aatgatgact aagccaatta gtattcgtct aaatattttc actttctccc accttttcta
    64681 tctgagtgac ccctttttct taatcaagta tgattatacc ttaaaaaaat aagagagaaa
    64741 tgcaaacttt ccagcatcaa ataaaaaaag acggaatatc catttgaata tccgcccttt
    64801 ttgtatgttt atttttattt agcacataaa cgatacacag cttctgcata aatttccatt
    64861 gctttataca tactacttaa ttcccatcgt tcattcgcct ggtgcataaa gtcaggagta
    64921 tcagggaaca tcgcaccgaa tgccacacac tggttcatcg tacgagcaaa agtagcgccg
    64981 cctgatacaa acggttcagt catgtctcca gtaatatcgc gatatgtccc caatagattt
    65041 ttcactaact cactgtctag tggcacgtat aatgaatcaa ggaagtcaaa ttcttcataa
    65101 gtcaacccat atttttctgc tgttttagtt aatttagcta ctaaatcatc tttcttgaat
    65161 gtaacaggga ttctcatatc tacaccgatt tttgtttgtt ctggtgtgat ttccaaactt
    65221 gcaaagttca tcgttagctc gccggattgt tcatcttctg ttttgcccac gacagcttca
    65281 ccagttgcat tttcttgaac taattttcct aagaaattga ttgggccaaa atcaaatact
    65341 tctgaaagag caattgccag acgagaaata gcattcactc cttgtgctgc atctttcgcg
    65401 tggatacttt taccaagaac gacgatgcct tcaccttgtt cttcgaaatc gaattcgtgt
    65461 tttttcaatg cttcttttac ttcagaaagc ttttctccag agtaaggagc tgcatcagga
    65521 acaacattca acgctcctcc agcttttaca gaaaactcgt tcgttcctgg tcctgtcaag
    65581 taagcttgca ataagccttt ttctgcataa attaaaggaa attcagcatc tggcgcaaat
    65641 ccttgcgtaa ttccttcttc tttttcgtta tatttttcta aacaacgcca taaattttct
    65701 tcatctgtac caaagataaa acgaatacgt gtcttgaatt ccacgccagc atcaatcaaa
    65761 gctttgacgg catacattgc cgcaatagaa ggacctttgt catcttggga tccgcgacca
    65821 actaaccagc cgtcttttat agttggatcg aatggttttg tttcccaatt attttcgtcc
    65881 cctgctggaa caacgtccat atgacacaag ataccgaata attcatctcc agagccaatc
    65941 tctgaataac cgtaatagcc ttctggatct ttaaatgttc taaatcctag cttttcactg
    66001 atttccaata ctttatccaa agcttcaatc acttttttac cgaagggatg tccttgtcct
    66061 gaatctgctt catctagtac ggaaggaatt cggatcaatt cgctcaatga ttctaatgct
    66121 tgttcatgat gttgttctgt cacaaatttt ttcatgatat tatcctccta atatgttaaa
    66181 aagggtcatg tcaaattcct ccgacacaac ctcttcttct caaataatga cgttttaagc
    66241 ctgctccatc agcaagcaga atgttcttaa caaatgatga aagaaaaaac actcactgaa
    66301 tggagctatt gacttatcca cgtgcttatc gatagccgtt tatcggtttc ttcattctta
    66361 tgatagacct tgtacctgta tttgtctagg tttagaacat tgctgctaca cctaggatca
    66421 cacagatggc tacaaataat atcgcaatta atttaccggt aaatttccac cacactgaaa
    66481 catcgaaacg agcaattgct acagcaccca ttacgatagc agatgttggt gtaattaagt
    66541 ttactaaacc agatgcagat tgataagcag tgattactaa atccttaccg acgccggcaa
    66601 attcacccat aggtcccatg attcccattg ttgcagcagc taagccggaa gttgaaggaa
    66661 tcaagaatga catagggata tagaaaataa atgtaataat gatgaataca cttgaagata
    66721 atgaacttaa tccttgttcg ccccaatgta agatggtgtc tgtgattaat ccattgttca
    66781 taaccacttg gataccacga gcaacagcta ctacgattgc tacaccgatc aaatcagaag
    66841 caccagctaa aaattcagag acaaattcag actctttcat gccataagtg attgctacta
    66901 cgatggacat tactaagaat aacatagtaa tttctgggaa gtaccagtca cctaatggaa
    66961 gcatgctttt acctagaacc gtacctagta ccggaaggtt tgttaaccag tttgtcaatg
    67021 attcaaaaat cgtgaaattc gcattcaagg ttgtccaagg aatcaaactg atgatcatga
    67081 taccaaaagt aataaagaac aatacattaa catgtttttg ttttttcgtg attacttctt
    67141 gacgaccgat tgcttcaata tcgaaatgct tcatatcttc tttacgttgg ttgtatacta
    67201 atgattttgt tggatctttt tcgatctttg atgcataacg atacacatat acaatagaaa
    67261 tagctaacaa aataacgaac atcaagaatc gaagaccaat accttcaccc atcgaaatcc
    67321 caacagcttg tgaagctacg cctgttgcaa aaggatttac cgttgaagct agacagccta
    67381 cttgagaccc tactaatacg attgctacag ctactactgt atcaaagcct acagccatca
    67441 tgactgggat cagtaaagca tagaatggaa tcgtttcttc tgccattccg taagtagagc
    67501 cgcctaatgc aaataacagc atcaatactg gaataagcat tttttctttt cctttgaatt
    67561 tcttcacaac tgaagcaatc ccggcatcta gtgcccctgt tttgttgata atacctaaaa
    67621 atccaccaac aaccaaaatg aagaaagaga ttgggattgc agcaggtgtt tctttagtta
    67681 gctcccccgc tggtacacct agcatcccat tgattggcgc catgaaaata tcccacagcc
    67741 cttgaggatt ttgttgtact cgttcatatg atccagcgac gatgttgcct gcatcgtcta
    67801 cactatagtg cccagctggt ataaaccaag taagtacagc gattactgca ataataataa
    67861 ataagaccgt atacgctgaa ggcatttgaa attttttctt ttttgtttgt tccatcttct
    67921 tcttcctttc ttttccgtta gagacaacaa ttttggctct aatgttattt tatcaaaaag
    67981 agtatcagaa caaaaataat aacacgcatt ttgtaaaact tttgttcaaa aagttcgttt
    68041 ttccctattc cctcctcttt tttcaggttt ttaaagcttt cttctttttc attgtagcgt
    68101 ttcctttttt ttataaacaa acattttcgt cttttaaaag gagaagaatt tcacatttgc
    68161 aaagaattga ttgattttta tgcataaatc aaaaaaatac tcaaaacaaa caaataaaac
    68221 gtttacatta ttgcatgtct tgtatttttt tccaaaaaaa aagaccaaga aatttcttga
    68281 tctttttgat atttatttga ctgctgtatg acgttgttcg aactgatgtt gttttcgact
    68341 taaccatgga agaagttgcg catgcagcac taaaaagaca gcactcacga tgaatccttt
    68401 gatcaagttg aaaggaacga tcccaatcag tacatagttt gctaaagaca tgcccagcat
    68461 ctgtgttgcg ttcagcccta aaaacattaa gtaaagaggc gtaataacga aataatttgc
    68521 gatactcata aaaatagtta gagcgatggt tcctgtaatg acacctaaaa atttgtttct
    68581 tcctttatgc tgtttcttta cactaaagaa ataataaatc gggaatgtaa agatcgttgt
    68641 tgataagaaa ctagcagtgt ctcctaccaa attatccgga gaaaaacctg tagtcagcag
    68701 atgtaatact gaacgcaaga acgctgttgc aactccggcc gctggaccga ataagaacat
    68761 gctgatcaat accgagatat cactaaaatc gatcttcaaa aaactaaaag ccggcatgat
    68821 cggaaaagca aaatactgta aaactaatgc gatcgcagca aacatcgcta ctgcaaccat
    68881 tttctgtaca cgggtgttct tcatttgaaa tcctcctgtt aggactcctc ttcagcgaac
    68941 tttttgacgt ttctctccaa atgaaaaaac tctattttcc agggaaaata gagttagagt
    69001 tatttgatca agcgtcgtca aataagctct atcttcttta tccagactat actgtcggta
    69061 tcggaatttc accgattcag ctattttttt gcaaaatagg tcgtggacta taaccaccgg
    69121 tcgggaattt caccctgccc ctgaagacga accttatata atttttgttt acatattcat
    69181 tatacatatc tattcaaaaa acgcaacatc taacacttat aaaaagtaag tgttcatttt
    69241 gagtggttca gcaaactgct gacttctttt ttgttcagtt cacggtaatc cccaggacgt
    69301 aggccttgta aagtcagatc tccgtatttt tcacgtttta gtttttgcac aggaagacca
    69361 actgcttgaa gcatattttt cacttgatga ttacgtcctt cgtggatcgt caattccacg
    69421 atactgtggt ttgtcttagg atccactgat aaaatttgga atttagctgg agatgttttt
    69481 cgtccttcga tctttattcc ttttgtcaaa ggtgcaagca tcgattttgt agcgatccct
    69541 tttacctttg caacgtaaac tttatccact tcatgttttg gatgtgtcag gcgctgagca
    69601 aaatctccat catttgtcag tagcaagatc cccgaagtat cgtaatccag tcgacctaca
    69661 ggatagatac gttcttttac catcggcaaa agatccgtaa caacttttct tcctttgtca
    69721 tctgcaacag cagaaataac tcctttaggt ttgtacaata aatagtaacc gtattcttct
    69781 tgataaattg ggacttcatc cacttccaca gtgtcatgtt tcccaacttt tatccctaat
    69841 tcccttacaa cttgtccgtt tacttttaca cgtcctgcaa ggatgaattc ttctgctttt
    69901 cgacgagaag tgatgccagc gtgggcaatt actttctgca atctctccat tacaattatt
    69961 ctcctttatt cattccatca aagaatagat ctggtgacac gtcttcttca agtgaaattt
    70021 ccatttcttg tgtatcaggc agttcttcta atgatttcaa accaaaataa tctaagaagt
    70081 agccagttgt tccatataat atcggccgac ctggtccttc tactctacct ttttcttcaa
    70141 tcagtttatg ggcagctaga cgctgtaccg ctcctgaaac ctgaactcct cgaatctgct
    70201 cgatttcagc tcttgtgatt ggctgtttat aagcgatgat tgctaaggtt tcgacggcgg
    70261 cttgagataa tgtgtttgat gtcccttgcg catatcgctt aagtaaggga gccagctctt
    70321 ttttagtcgt taatacataa tggctttccg tttcaaaaat atgcaaagct gagtgcgagt
    70381 tttgagtgta agattctttt aattctttca ctaaacttgt gacttctgct tcgctgagat
    70441 ttaacagtcc gcttaattct tcattactga tcccttcctc gccaacaata aaaagaaggg
    70501 cttcaagttc acttaatttc gtcatgttcg gtatctccta ctgctggata aagcataatt
    70561 gattcatagt tttctttttg ttgcgcaatg atctgccctt ttttcatcaa ttctagcaaa
    70621 gccataaaag tagtgacaac ttcactttta gaaggtgact caaaaaaaga atcgaaagta
    70681 cagccatgcg catttctttt tatacgctct tcgataaata ccattcgttc ttcgatcgtt
    70741 gtgtcatcgg gcgtgatcgt tttttccact ttttgagaaa atttcttacg ttctaagatt
    70801 ttctgcatgg cacggatcaa atcgattttt ttgacttgtc ctcgcttcaa cggcttttca
    70861 gcatccgcta acccatcgat gttcataggt tcttttgtgt aataaagact tcgttcctct
    70921 gctttttctg tcagtctttc agctgcatat ttatatttac ggtattctaa aagctgagtg
    70981 accaattctt ctcgaggatc ttcttcccat aattcttcat cgtctgtgac gaattcttgg
    71041 acaggaagca atgtcttgct tttgattgcc atcaatgtag cagccatcac taagtattct
    71101 cctgcaacag ctagctcgag tgttttcatt gtatggatat aattcatata ttgctccgtg
    71161 atcgtagcga tcggtatatc atatatatcg atttccattt gctgaatcag atgaagcagc
    71221 agatcgagag gaccctcgaa tacatctaat ttaatattga tctccgtcaa ctcattcact
    71281 ctttcttctt tttctttgct agccattttc caatgtaagg ctctgtgatt tcagttgcac
    71341 ggatggagac atccgggtac ttttcctgta attcatctaa catttgaaag cccatattct
    71401 caccgcgata agacggattc aaagaaatgt catggatgat cagctgatcg ttcgttgccc
    71461 agtaaatacc aataatccct tgaatgttgg ttgaaccttc tggcgtaaag aaaaaaagtt
    71521 cataatcgtc ttcagattcg tacgtatcaa tctccttcaa caaagaagtt ttacctgtca
    71581 gtttcttatg gaaactcaat agtcccatag caattttacg gttttctttc cggtaatgtg
    71641 ttaacatctt ctcaccttcc tatgactaag cccttggaaa atgctgctta taaacatccg
    71701 tcattctttt cttcgtgata tgtgtataaa tctgagtcgt agagatatcc gcgtgaccta
    71761 acaattcctg tactgtccgc aaatcagctc cattttctag cagatgtgtg gcaaagctat
    71821 gccgcagcgt atgtggtgtt acttctttgt aaatcccagc ctctcgtact aactgcttca
    71881 gatttttcca gattccttgc cgagaaagac ctttcccatg attattgaca aatacatgca
    71941 tttcagatgc gtcctttaca agtaatggac gtgcttcgtc taagtagcgt tccagccatt
    72001 ggatcgcata atcacctaaa ggaatgatcc gctctttatc tccttttcca actgtctgta
    72061 ccagtccaag agaaagatga agatctccca atttcaatcc aatcaattca ctgacgcgca
    72121 tcccagtagc atacatgact tccaagattg cacgatctct tatccctaac gtttttgtcg
    72181 tatcaggtgc ttcaatcagc ttttctactt ctgtcagagt caatgtactt ggtaatttct
    72241 gtgctttctt cggcgtatcg atatgttgca tcggatcatg atcagtgata cgctcttgcc
    72301 gtaaaaactg atggaatctt ctgagacttg agatcatccg agtaacagtt gctgtcgctt
    72361 ttttttcttc atgcaacttc tccagaaaac ggatgactaa aaagcgatcg acatcctgcc
    72421 atgaagcaat tttctgctcc tgtagaaaat gcaagtactg ttccaaatca cgttcatagc
    72481 tttgtcgtgt attggcggac aatccccgtt caatattcaa gtagtggaga taatcgttga
    72541 tttgctcttt cataataatc cccctcatgc ctctctatca tatcagatac cgcttcattc
    72601 tgatagtctt tttccataat ctgagcaaag aaaaagccgt ctagacactc agacggactg
    72661 gtttcttttt tctttttcat agcattcctg acagattcca tggaacgtta gccgatgatc
    72721 ttttactaaa aaatgataac gttcttctac tacttgctcc acttcaagta aaagatcctc
    72781 ttctacttcc tcgatcgtgc cgcagttcaa gcatagtaaa tgatgatgga aatgtttggc
    72841 gccttctttt ctcaaatcat aacgggctaa tccatcatta aaacttactt tatcgacaat
    72901 tttcaattct gtcaagattt caagggttcg ataaacagta gcaagtccaa tttccggact
    72961 cttttttttc actaaaaaga agatttcttc tgcagataaa tgctctttct cattttccaa
    73021 aagcacaagc agagtagctt ctctttgcgg tgtcagctta aaccccgctt catgtagctg
    73081 ctgttttgtt tttttcatcg ccgaaatagc attcatgacc atttactcaa ccccaacaat
    73141 ttataataat tacaaataaa aaaagatata acactatgtt aattaaaatt attataagct
    73201 agttaagaaa aacatgcaag ggattctcaa ttagattttt tgactagttt tgtcacaccg
    73261 ttttcttgtg taatcaatcc ttgtttcaaa agattaccta atgcgcgctt aaatgctcct
    73321 ttgctgatac caaaagcttt catgatttct tctggatccg atttatctgt aaagttgatt
    73381 tgctgatctg cagaacgttc taaaatggtt aaaatcattt gtgcatcatc tgatatagct
    73441 tcatatgctc ttggcttcaa tgaaagattc agtacaccgt ctggtcggac accaatcact
    73501 cgacctttta tctgctcgcc tagacgaggt tcattatatc gttcagaagg atggataaac
    73561 ccaagataga aatcttccgt taaaacgtac gtacctgtta atttcaagcg gtatgctgtt
    73621 cctatcacat ctttgttttt catttcttct gttccatatt tgcttaaaga tttgaatatt
    73681 ttttcatctg ctaaactgcc ccaaatacgg tcttttgcat caactctaag ggaaatcatc
    73741 aagcgatccc cttttttagg ccatagctct gtcattgtcg gcaattcatc aagagatacg
    73801 acaaagtctt tatctggaag accgatatcg acaaacgcac ctaaatcttt tcgtgtagca
    73861 gtaacgattc caaaaccgta atgaccgata cggcttttag gaatttgtgt agtgatccga
    73921 ttttcatgtt tttgattttg gtaaccgaat ccttcaactg cttcaccgat tttgtgttca
    73981 ccttctgatt tgcttaagcc aaaggtttgt ccgttttttt ggacaaagta gtttttttca
    74041 ttttcatcaa taataatacc tgtaaatata gttgctaata aatcgttcat ttttttctcc
    74101 ctctatagtg aaaggttttc ttaatacatt tctttgctat cataacataa tgttatctac
    74161 ttgaatagct gagccttggt ttggaaaggt gaaaaaagga gtatgacaac agttgtgtca
    74221 tactcccctt tttcgaataa acggtgttaa acggcaggct cacagcctct ttcatttgcc
    74281 taaaattaat tgctcccatt tcctccgaac catccagttt tacagttgat ggttacgatg
    74341 taaaatggca aagcactttc tccaatgcct ttcatcaatg cagattttgt tgaagtggca
    74401 tatagattat aatagccttc cccattttcg attctggctt tttctaatct gtaacctcct
    74461 tcaacgatat atccacgttg gatacatgta gcaatcactt tgctttggac acctggtgcc
    74521 cacgtccatg ctggattaga tgcatcggca atatcacttg ctctggcaga tttgattggc
    74581 tgattcgctg agtttgaaga ggaaggggtc gaggatgccg cttcttgctg tgctgcttgt
    74641 gcgaccgcag cttgttgagc ggcttgagct gcagctgctg cttgagcggc ttgttttgct
    74701 tgttcttcag ctgctttttt cgcttcttct gcttttttct tttcctcttc ttcttttttc
    74761 tctttatcag tgagcatctt atctacttgt ttcaattgtt cattcaactg agcagataga
    74821 tctgtatttt tcactttttc tactgcttct tttgccgtct tgtattggtc gcgtgttgct
    74881 gaatccacta cttttccgtc tttaaagact atagctgttt tttctttagc tgtttgcaat
    74941 tcagcatatt gatttttagc ttctgtttgt gcttgttgaa tcaattttcc aaaatctgtg
    75001 ttatccgttt cgattgcttg gatctcttta tctgctttca acttgatgtc atctgctaga
    75061 tgatcatcga cgatggcagg tgctatgaac cactcattca ctttttggat atctcggatc
    75121 ttagattgga tatcttggta agttgtttct aactctgaat atcctttttc attcttaaga
    75181 ctggataaat cattttttag ttttgataaa tcttgatgaa tcatatctgc acgaataaat
    75241 tgatggtgat catctgtata aaaggcagca agtttctcat gaagttcttc catttgttgc
    75301 tgtctttttg cttctgctgc tacttcggct tctacttttt gatgatggtc ataataagcc
    75361 cagcttcctc caccgagtag aagtactgct gctaaaacga gataaggtac tttttttgat
    75421 tttttctttt gcgctttatc tggatctgtt ttttctaagt ttgattcttg atgtgttttt
    75481 tcagtatctg gcacgattgt tattgatttc gcttctgctt caaacagctt aggctggttc
    75541 tcttcttttt ctatttttgc ttcaagatca gtaccctctt tgcttacaga ttgattttca
    75601 gcatcggatt cactatttat ttcatcgggc tctgttgact ttttgtctgt gttttcgagt
    75661 atttcttttt tctctgcttc cggcagttta ttcgtttttt ccttttctaa ttgtttttca
    75721 gtaaatactt cagttttttc tgtgatatcc gtttttacgt cttttatttt tactgtttct
    75781 ttacctgtgg cgttttctct atcagagtct ttttcagttt cttgttcctt ttctggctct
    75841 actttgtttt cctgtgcaat tttttcactg atcattttga gcagctcttt cgcgtgctct
    75901 tcttttgtat cttcacgatg tgctttgata taagcggata gtatcgaatt ttcttcctca
    75961 ttatcgacga tttctttcag ttcagctact cttctttttt gttttgattc aagcgtttct
    76021 tcttgattct ttcctgattc ttccgaagtc tcatgaacag ttgctttctt ctgttcattt
    76081 ttctctatat tagttacttg atcgtgagca ggtggttctt cgtcttctgg ttctgctttt
    76141 tcgaataatt ccattacaga ttctagaggt aaatctttca attccgacca ttcgattgga
    76201 tcgtttaatt ctgtatcagg aaagactgca tcttcagttg atttatcctg catagctgca
    76261 tctgtatttg tttcttcaat tgattctttt atttgctgat cttctgcagt tatttgatga
    76321 ccgcagtctg gacagatagt attctgctcc atttttttcg atccgcaatt tggacatttt
    76381 ttcatcactt agcgatcggc tcctttacta ggtttacgct accatttaat ctatcatatt
    76441 ctatacgtca cgccaatagc ttatttttag gatttactta aaaataatga atgaatttcc
    76501 ttcctataga aaaaaaagct tgagactgcg tagtctcaag ctt
//
LOCUS       DAZULR010000007        74170 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.007, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000007 DAZULR010000000
VERSION     DAZULR010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 74170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 74170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..74170
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.007"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(530..2026)
                     /gene="lysS"
                     /locus_tag="ACG8ZV_000502"
     CDS             complement(530..2026)
                     /gene="lysS"
                     /locus_tag="ACG8ZV_000502"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HFS4995872.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKAGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(2137..3141)
                     /gene="dusB"
                     /locus_tag="ACG8ZV_000503"
     CDS             complement(2137..3141)
                     /gene="dusB"
                     /locus_tag="ACG8ZV_000503"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HFS4995873.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(3142..4029)
                     /gene="hslO"
                     /locus_tag="ACG8ZV_000504"
     CDS             complement(3142..4029)
                     /gene="hslO"
                     /locus_tag="ACG8ZV_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HFS4995874.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(4246..6357)
                     /gene="ftsH"
                     /locus_tag="ACG8ZV_000505"
     CDS             complement(4246..6357)
                     /gene="ftsH"
                     /locus_tag="ACG8ZV_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HFS4995875.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(6447..6992)
                     /gene="hpt"
                     /locus_tag="ACG8ZV_000506"
     CDS             complement(6447..6992)
                     /gene="hpt"
                     /locus_tag="ACG8ZV_000506"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HFS4995876.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6992..8437)
                     /gene="tilS"
                     /locus_tag="ACG8ZV_000507"
     CDS             complement(6992..8437)
                     /gene="tilS"
                     /locus_tag="ACG8ZV_000507"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HFS4995877.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8557..9027)
                     /locus_tag="ACG8ZV_000508"
     CDS             complement(8557..9027)
                     /locus_tag="ACG8ZV_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1 domain-containing RNA-binding protein"
                     /protein_id="HFS4995878.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(9073..9498)
                     /locus_tag="ACG8ZV_000509"
     CDS             complement(9073..9498)
                     /locus_tag="ACG8ZV_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HFS4995879.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9565..9834)
                     /locus_tag="ACG8ZV_000510"
     CDS             complement(9565..9834)
                     /locus_tag="ACG8ZV_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HFS4995880.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9845..11440)
                     /locus_tag="ACG8ZV_000511"
     CDS             complement(9845..11440)
                     /locus_tag="ACG8ZV_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFS4995881.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(11455..14976)
                     /gene="mfd"
                     /locus_tag="ACG8ZV_000512"
     CDS             complement(11455..14976)
                     /gene="mfd"
                     /locus_tag="ACG8ZV_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HFS4995882.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14993..15553)
                     /gene="pth"
                     /locus_tag="ACG8ZV_000513"
     CDS             complement(14993..15553)
                     /gene="pth"
                     /locus_tag="ACG8ZV_000513"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HFS4995883.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15906..16880
                     /locus_tag="ACG8ZV_000514"
     CDS             15906..16880
                     /locus_tag="ACG8ZV_000514"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HFS4995884.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            17050..18450
                     /locus_tag="ACG8ZV_000515"
     CDS             17050..18450
                     /locus_tag="ACG8ZV_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HFS4995885.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18528..19250)
                     /locus_tag="ACG8ZV_000516"
     CDS             complement(18528..19250)
                     /locus_tag="ACG8ZV_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFS4995886.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(19329..19835)
                     /locus_tag="ACG8ZV_000517"
     CDS             complement(19329..19835)
                     /locus_tag="ACG8ZV_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFS4995887.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSINHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19958..21757
                     /locus_tag="ACG8ZV_000518"
     CDS             19958..21757
                     /locus_tag="ACG8ZV_000518"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HFS4995888.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21825..23399)
                     /locus_tag="ACG8ZV_000519"
     CDS             complement(21825..23399)
                     /locus_tag="ACG8ZV_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NlpC/P60 family protein"
                     /protein_id="HFS4995889.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23654..24163)
                     /gene="mreD"
                     /locus_tag="ACG8ZV_000520"
     CDS             complement(23654..24163)
                     /gene="mreD"
                     /locus_tag="ACG8ZV_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HFS4995890.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(24167..25021)
                     /gene="mreC"
                     /locus_tag="ACG8ZV_000521"
     CDS             complement(24167..25021)
                     /gene="mreC"
                     /locus_tag="ACG8ZV_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HFS4995891.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(25176..25814)
                     /locus_tag="ACG8ZV_000522"
     CDS             complement(25176..25814)
                     /locus_tag="ACG8ZV_000522"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HFS4995892.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25815..26465)
                     /gene="rpe"
                     /locus_tag="ACG8ZV_000523"
     CDS             complement(25815..26465)
                     /gene="rpe"
                     /locus_tag="ACG8ZV_000523"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HFS4995893.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGRFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(26478..27377)
                     /gene="rsgA"
                     /locus_tag="ACG8ZV_000524"
     CDS             complement(26478..27377)
                     /gene="rsgA"
                     /locus_tag="ACG8ZV_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HFS4995894.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27542..29611)
                     /gene="pknB"
                     /locus_tag="ACG8ZV_000525"
     CDS             complement(27542..29611)
                     /gene="pknB"
                     /locus_tag="ACG8ZV_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HFS4995895.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29608..30348)
                     /locus_tag="ACG8ZV_000526"
     CDS             complement(29608..30348)
                     /locus_tag="ACG8ZV_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HFS4995896.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(30361..31719)
                     /gene="rsmB"
                     /locus_tag="ACG8ZV_000527"
     CDS             complement(30361..31719)
                     /gene="rsmB"
                     /locus_tag="ACG8ZV_000527"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HFS4995897.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKMLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31719..32657)
                     /gene="fmt"
                     /locus_tag="ACG8ZV_000528"
     CDS             complement(31719..32657)
                     /gene="fmt"
                     /locus_tag="ACG8ZV_000528"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HFS4995898.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKKAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32650..33141)
                     /gene="def"
                     /locus_tag="ACG8ZV_000529"
     CDS             complement(32650..33141)
                     /gene="def"
                     /locus_tag="ACG8ZV_000529"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFS4995899.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(33156..35564)
                     /gene="priA"
                     /locus_tag="ACG8ZV_000530"
     CDS             complement(33156..35564)
                     /gene="priA"
                     /locus_tag="ACG8ZV_000530"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HFS4995900.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35817..36122)
                     /gene="rpoZ"
                     /locus_tag="ACG8ZV_000531"
     CDS             complement(35817..36122)
                     /gene="rpoZ"
                     /locus_tag="ACG8ZV_000531"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFS4995901.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(36127..36741)
                     /gene="gmk"
                     /locus_tag="ACG8ZV_000532"
     CDS             complement(36127..36741)
                     /gene="gmk"
                     /locus_tag="ACG8ZV_000532"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFS4995902.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEKRMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            complement(37228..37512)
                     /locus_tag="ACG8ZV_000533"
     CDS             complement(37228..37512)
                     /locus_tag="ACG8ZV_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995903.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(37530..38420)
                     /locus_tag="ACG8ZV_000534"
     CDS             complement(37530..38420)
                     /locus_tag="ACG8ZV_000534"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YicC/YloC family endoribonuclease"
                     /protein_id="HFS4995904.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFVLDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(38440..38658)
                     /locus_tag="ACG8ZV_000535"
     CDS             complement(38440..38658)
                     /locus_tag="ACG8ZV_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HFS4995905.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(38628..40328)
                     /locus_tag="ACG8ZV_000536"
     CDS             complement(38628..40328)
                     /locus_tag="ACG8ZV_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HFS4995906.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            40595..41368
                     /locus_tag="ACG8ZV_000537"
     CDS             40595..41368
                     /locus_tag="ACG8ZV_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995907.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(41449..42018)
                     /gene="thiT"
                     /locus_tag="ACG8ZV_000538"
     CDS             complement(41449..42018)
                     /gene="thiT"
                     /locus_tag="ACG8ZV_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015234 - thiamine transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015888 - thiamine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HFS4995908.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(42084..42186)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(42192..43163)
                     /locus_tag="ACG8ZV_000539"
     CDS             complement(42192..43163)
                     /locus_tag="ACG8ZV_000539"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HFS4995909.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(43257..44630)
                     /gene="glmU"
                     /locus_tag="ACG8ZV_000540"
     CDS             complement(43257..44630)
                     /gene="glmU"
                     /locus_tag="ACG8ZV_000540"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HFS4995910.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(45133..45951)
                     /gene="purR"
                     /locus_tag="ACG8ZV_000541"
     CDS             complement(45133..45951)
                     /gene="purR"
                     /locus_tag="ACG8ZV_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HFS4995911.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(46118..46942)
                     /locus_tag="ACG8ZV_000542"
     CDS             complement(46118..46942)
                     /locus_tag="ACG8ZV_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HFS4995912.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(46915..47595)
                     /locus_tag="ACG8ZV_000543"
     CDS             complement(46915..47595)
                     /locus_tag="ACG8ZV_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFS4995913.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(47618..48556)
                     /locus_tag="ACG8ZV_000544"
     CDS             complement(47618..48556)
                     /locus_tag="ACG8ZV_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HFS4995914.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(48801..49652)
                     /gene="ispE"
                     /locus_tag="ACG8ZV_000545"
     CDS             complement(48801..49652)
                     /gene="ispE"
                     /locus_tag="ACG8ZV_000545"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050515 - 4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HFS4995915.1"
                     /translation="MELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADHLFFE
                     EITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAGLGGG
                     STDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQVLPS
                     MPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMGNSLE
                     DITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGFCEEV
                     YLVRTLQ"
     gene            complement(49806..52379)
                     /gene="mprF"
                     /locus_tag="ACG8ZV_000546"
     CDS             complement(49806..52379)
                     /gene="mprF"
                     /locus_tag="ACG8ZV_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HFS4995916.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            52520..53326
                     /gene="proC"
                     /locus_tag="ACG8ZV_000547"
     CDS             52520..53326
                     /gene="proC"
                     /locus_tag="ACG8ZV_000547"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HFS4995917.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLIDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(53405..54961)
                     /gene="rny"
                     /locus_tag="ACG8ZV_000548"
     CDS             complement(53405..54961)
                     /gene="rny"
                     /locus_tag="ACG8ZV_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HFS4995918.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(55372..56421)
                     /gene="recA"
                     /locus_tag="ACG8ZV_000549"
     CDS             complement(55372..56421)
                     /gene="recA"
                     /locus_tag="ACG8ZV_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HFS4995919.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(56530..57771)
                     /locus_tag="ACG8ZV_000550"
     CDS             complement(56530..57771)
                     /locus_tag="ACG8ZV_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HFS4995920.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(58011..58589)
                     /gene="pgsA"
                     /locus_tag="ACG8ZV_000551"
     CDS             complement(58011..58589)
                     /gene="pgsA"
                     /locus_tag="ACG8ZV_000551"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HFS4995921.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(58798..59721)
                     /locus_tag="ACG8ZV_000552"
     CDS             complement(58798..59721)
                     /locus_tag="ACG8ZV_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RodZ domain-containing protein"
                     /protein_id="HFS4995922.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(60460..61746)
                     /locus_tag="ACG8ZV_000553"
     CDS             complement(60460..61746)
                     /locus_tag="ACG8ZV_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFS4995923.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(61739..63007)
                     /locus_tag="ACG8ZV_000554"
     CDS             complement(61739..63007)
                     /locus_tag="ACG8ZV_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFS4995924.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYSDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            63259..63720
                     /gene="mscL"
                     /locus_tag="ACG8ZV_000555"
     CDS             63259..63720
                     /gene="mscL"
                     /locus_tag="ACG8ZV_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HFS4995925.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(63779..64225)
                     /locus_tag="ACG8ZV_000556"
     CDS             complement(63779..64225)
                     /locus_tag="ACG8ZV_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4995926.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGE
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(64318..64563)
                     /locus_tag="ACG8ZV_000557"
     CDS             complement(64318..64563)
                     /locus_tag="ACG8ZV_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HFS4995927.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(64678..65256)
                     /locus_tag="ACG8ZV_000558"
     CDS             complement(64678..65256)
                     /locus_tag="ACG8ZV_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFS4995928.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSVISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(65333..65863)
                     /locus_tag="ACG8ZV_000559"
     CDS             complement(65333..65863)
                     /locus_tag="ACG8ZV_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HFS4995929.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(65867..66727)
                     /gene="rlmB"
                     /locus_tag="ACG8ZV_000560"
     CDS             complement(65867..66727)
                     /gene="rlmB"
                     /locus_tag="ACG8ZV_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HFS4995930.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(66720..67115)
                     /locus_tag="ACG8ZV_000561"
     CDS             complement(66720..67115)
                     /locus_tag="ACG8ZV_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HFS4995931.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(67112..68524)
                     /gene="cysS"
                     /locus_tag="ACG8ZV_000562"
     CDS             complement(67112..68524)
                     /gene="cysS"
                     /locus_tag="ACG8ZV_000562"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HFS4995932.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(68521..69057)
                     /gene="epsC"
                     /locus_tag="ACG8ZV_000563"
     CDS             complement(68521..69057)
                     /gene="epsC"
                     /locus_tag="ACG8ZV_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase EpsC"
                     /protein_id="HFS4995933.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(69143..69382)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(69379..70839)
                     /gene="gltX"
                     /locus_tag="ACG8ZV_000564"
     CDS             complement(69379..70839)
                     /gene="gltX"
                     /locus_tag="ACG8ZV_000564"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HFS4995934.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(71009..72166)
                     /locus_tag="ACG8ZV_000565"
     CDS             complement(71009..72166)
                     /locus_tag="ACG8ZV_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HFS4995935.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(72200..73570)
                     /gene="radA"
                     /locus_tag="ACG8ZV_000566"
     CDS             complement(72200..73570)
                     /gene="radA"
                     /locus_tag="ACG8ZV_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HFS4995936.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKTAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(73633..74160)
                     /locus_tag="ACG8ZV_000567"
     CDS             complement(73633..74160)
                     /locus_tag="ACG8ZV_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HFS4995937.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
BASE COUNT        20262 a        16155 c        13279 g        24474 t
ORIGIN      
        1 gagtgtttcc cgattcattt ttggctgccg tagcaacttt tatatcatat cagagagaca
       61 agcgattgtc aactcttttt taaaagtttt tttcgatttc gtttttcgaa atctttcggc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcgt
      241 tagtaacatg tcaataactt ttttgttatg tttttgaata aatattttct tctgtctttt
      301 ggacaagtaa taatatacca actaaattta gcttggtcaa cgaatttttt gtattttttc
      361 aagttttttt caataaacga ttattcataa cttttctttc tttatcgttc gttttcgtct
      421 tctttaatgt ctagaatagt cggcattagc ttttgaactt tcgttattat ttattccttt
      481 ctacacagca aaagctgcct aaggaattcc ttagacagct tttattcgat tatctcattg
      541 ttgggaatag caaaacatcc cgaattgatt gtgcatcagt tagcaacatt actaatctgt
      601 cgatcccgat gcctagacca ccagttggcg gcataccgta ttctaaggct tccaagaagt
      661 cttcgtctac accgtgagct tcgtcatttc ctagttcacg ttctttttct tgcgcttcga
      721 atctttctct ttgatcaatt ggatcgttca gttctgtaaa ggcattagca aattcgcgcc
      781 ccactatgaa tagttcgaat cgatctgtga atcgaggatc ttctggattt ttcttcgcta
      841 aaggcgaaac ttcgactgga tgtccgtata caaacgtcgg ttgtgtcaat gtttcttcaa
      901 caaatgtttc aaagaattca ttgataacat gtccgacacc catagcttcg gttacttcta
      961 cattgtgttt ttcggctaaa gctaatgctt cttccaatgt catttcttgc cagaagtcta
     1021 caccagtttg ttctttgatt gcatctacca tatggatgcg tttaaagtca ctttctaagt
     1081 cgacagcttg tccatcatat gtgatttttg ctgttcctag tactttttca gctgcgttac
     1141 ggataatacc ttctgtcaga ttcattacat cattgaaatc agtatatgct gtgtatgctt
     1201 ctaacatcgt aaattctgga ttatgtgtag tatcaattcc ttcattacgg aaaacgcggc
     1261 cgatttcata aactttttcc attccgccaa caattagtcg ttttaaatga agttctagcg
     1321 caatacgcaa atataaatca atgtccagtg cattatgatg cgtgataaat gggcgtgcgg
     1381 cagctccacc tgcctcattg tgcaatactg gtgtttctac ttcaatatag ccattgccat
     1441 ctaaatagcg acggatttcg ctgataattt ggcttcgttt cataaatcgg tcaaagcttt
     1501 cgcgattact gattaaatcc aagtagcgtt gtctgtagcg ttgttcaata ttcgttaagc
     1561 catggtattt atctggcagt ggacgaagtg cttttgacaa aatcgtgatt tctgaagctt
     1621 tgatagaaac ttcgcctgtg tctgttttca tgatttgtcc agttacacca aagaaatctc
     1681 caaggtctgc atgtttgaat acttcatagg cctcatcacc tacttggtct tttcttacat
     1741 aaatttgaat ttggccttca cgatcttgta gatgcgcaaa tccagctttc ccttttcctc
     1801 ggcgagtcat catacgacca gctacactag cggtcaatcc catttctgct agttcttctt
     1861 ttgttcttgg atcaaatagt tcatgcaatt cttctgagtt gtgcgtgcgt tcaaatcgtt
     1921 ttccaaatgg atcgattcca tcttcacgca attgttccat tttttgacga cgtacaagca
     1981 tttgatcatt taaatcttct acttgatgtt gttgttcctg tgtcacaaaa gttcctccat
     2041 tctcatgtta atctctttcc tataatgcca atgaaacaca aaaaaagcaa gccgaacttg
     2101 gaatttcggc ttgaaaattc acgaaaaact tagaaatcac aacgtttgtt tcaatagtac
     2161 tttttccgct ttttctacaa attgatccag caggtcattg atttcttgct gtttttctgt
     2221 ctgattgatt gctactttca ctttcgctgc tcgaggaatc ccttttaaat aataagccgc
     2281 atgtgttctg aattctctac aagctacttt ttctcctttg agatctgcta agcgttgtaa
     2341 atgaagttta gctgtagcaa ttttttcggc tggtgttggt tcaggaatca gttcccctgt
     2401 ttcgagataa tgctgtgtgc ggtgaatcat ccatggattg cccagcgctg cacgaccaat
     2461 catcacaccg tctgcaccga catagtcaag catccatttt gcatcttctg gcgttttgac
     2521 atccccgttc cccataaatg gaatcgtcaa atgttttttc acttctttca atacttccca
     2581 gtccgctttt ccttcataca tctgaacccg tgtacgtcca tgcatagcga tggcacttgc
     2641 tccagctgat tgtgctgcta atgcattttc tacagcaaag acgtgctctt catcccaacc
     2701 aatacgcatc ttgattgtta ctgggatatt tactgctgaa gaaacagctt ggaccatttc
     2761 gtatactttc tcaggatcta aaagccattt tgctcctgct tctgctttga ttactttatt
     2821 tactggacag cccatattga tatctattat atcggcagct gtgttttctt cgacaaattg
     2881 agcagcttca actagactat ctttatttcc gccaaatatc tgtaaactta atggatgttc
     2941 tgtttcttca atgtggagca tctctaaagt ttttttgttt ctgaaatgaa taccttggtc
     3001 actgatcatt tcacatacga ctaagcccgc accaaattct ttgacagtga ctcgaaatgc
     3061 tgaatttgtt attccagcca tcggtgcaac aacgacacga ttagggattt ccacattgcc
     3121 aattttccat gtgtgttcca cttaaatccc tcctaaggct tctttcttca atccatctaa
     3181 ttcttcttcg ctatacttgt atttgttatt acagaaagaa caaaccgctt ctgcaccgtg
     3241 atcttcgtct atcattgctt ggatttcttc tgcacctaac gcgataattg cttctgcaaa
     3301 tttttctttt gaacagtcac atttgaattg aacaggcatt ttttccaaaa tgttcaattc
     3361 ttctgtacca agcaatcctt tcaatatttc ttctggtgtc tgtccttcat ctaagagggt
     3421 agagattctt ggtgtcgttt ttaattgttc ttcgatcttg ctgattgttt cttcatcggc
     3481 acctggcatg atttggatca tgaatcctcc cgccgtcttg atgctgtcgt cagtattgac
     3541 caatacactc agtccaacag ctgaagggat ttgttctgag atagcaagat agtaagtaaa
     3601 atcttcagcg atttctccag aaacaatcgg cgtttgccca gaaaaaggtt cttttaatcc
     3661 taagtctttt gtgacagtaa acattccttg tgttccaact gctccccgca catcgatttt
     3721 accttcacta tttagaggaa gactgagatg cggatttttg atgtaacctt tcacatctcc
     3781 ctttccattt gcatctacta caattcctgt tgctggacca tcgccttgga ttcgaacagt
     3841 tagtttgtct tctcctttga gcgtcgcacc aagtagcaga ctaccgacca atgtccgtcc
     3901 caaagcagct gaggaggtgt gccaagtatc atgacgtctt tgtgcctccg ctacggtatt
     3961 tgttgcttga acggcgtatg ctcggacgaa tccgtcgtga gcaagtgcct taaccaaata
     4021 atctttcatt tgttatgtac tcctttttcc gtttttaaac tcatagtgaa tcatactagc
     4081 aactactgct tttttcaact ttggaatgct tcttttaaaa ataattcaga atcatctaga
     4141 aaacaggaca tcaccctatt tacaacttaa ataaagaaat ctcccgaaaa ccggtttttg
     4201 ttccggtttt cgggagtcat atcagatcaa ttgacctata tttttttatt tgtattgatc
     4261 gtctgaatga ttatcttctg attgttgaga atctgaatca tgttctgctt tattttcctc
     4321 attcagttca tgttttgctt cttcaaaatc acgtttttct tccgcttgtt tttcagcgtc
     4381 tttttcttcc aaagcacgtt ttgcttcttc aaaagttttc gcttcttttt cgcttggata
     4441 atcatttgac tcagtacctt caggcatcac accgtgttca aacaatgact tgattgcttt
     4501 ggcatccaat gtttcgaatt ccaaaagttt ttcagcaatc agtttatgct gtgcacgatg
     4561 agcttcgatg atttctcgag ctttatcatg agcttccatc aagatttttc gtacttcttg
     4621 atcaatctcg aaagcgactt gttccgagta agcttttgtt tgaccatagt cgcggccaac
     4681 aaacacttga tggtttcctt catattgaac aggacctaaa cgatcactca ttccatattc
     4741 tgttaccatg cttcgtgcta gagctgtcgc ttgctcaaag tcattggaag caccagttga
     4801 ttggacattg aagatgattt cttcagctgt acgtccacca agtaagccta cgatttgttc
     4861 aaacatatct tctttcgtca tcaagaactg atcttctttt ggtaaagcga tcatatatcc
     4921 gccggcgcgt ccgcgaggga tgatcgttac tttgtggacg acccgagcgc gactcaatac
     4981 taatccgaca atcgtatgac cagcttcgtg ataagcaacc atttcgcgtt cttttttgct
     5041 gattacgcga tcttttttag ctggacctgc aatcacgcga tcttccgctt catcgatatc
     5101 agaagcatcg attttctttt tatttcttct agcagctact aacgctgctt cattcaagac
     5161 attttctaaa tctgctccgg caaaacctgg tgtctgttga gccacaactt tcaagtcaac
     5221 gtcatctgcc atcggtttat tccgtgcatg gactcgcaag attgcttcac gaccttttac
     5281 atctggacgt ccaactaaaa tctggcggtc aaaacggcct ggacgtagta acgctgggtc
     5341 tagtacatca gaacggttgg ttgcagcaat gacgattact ccttcatttc cgtcgaagcc
     5401 atccatttct acaagcaatt ggttcaatgt ttgttcgcgt tcatcatgtc cgccgcccat
     5461 accggcacca cgttgacgac ctaccgcatc aatttcatca atgaaaatga tagctggtgc
     5521 gtttttcttc gctgtttcaa acaaatcacg aacacgactt gctccaacac cgacaaacat
     5581 ttctacgaaa tcagaacccg agatcgagta aaacggtact ccagcttctc cggcaacagc
     5641 ttttgctaat aaggttttac ctgttcctgg aggtccttct aaaagtacac ctgccgggat
     5701 acgggcacct aattcaacaa atcggcgagg atctttcaga aattcaacaa cttcaactag
     5761 ttcttgtttt tcttcttccg cacccgctac atcagaaaaa cgtacgcgat tagctttttt
     5821 gtctgcttct ttggcttttg atttaccaaa gttcatgaca cggccgccac cgccaccgcc
     5881 gccgccttgt tgtcccatca tcatgtaaaa gaaaaagatg atgattacga ttggcaagaa
     5941 gctaagcaat agggaaaccc atataccgct gcttgattct tcttttactg ttgtagcaac
     6001 tttgttttct tttgccagtt ctgttacttg gctcaatgtt gtatcatttg gcaaaatgat
     6061 tgttgtgaaa tgggtagtag tcgtatctgt tgaacctaag atagctaacc caccgctgtt
     6121 agcgacggtc tgctgttctt tgtattcacc agtgatctta tatacaccat ttgcaggctg
     6181 cacttcaaat tctttgatct tgcctgcttg tagttgttct gtgaattttg agtactcgat
     6241 atctgacgat cgctggccgt tattaccaaa aatgaaataa acgaccatta ccatcgctaa
     6301 gattacgagg acataataca aggcattttt catcatgccg ttgttctttt tgttcatagt
     6361 tgccctccct aagcgtcaat ttaatttaac agttttttat caatcctgac cattctattg
     6421 taccataatt taattgagat acagcattaa tttgattgat aaacactagg tttcaataca
     6481 ccgatgtacg gaaggttacg atatgcttct gcataatcca agccataacc gaccacaaat
     6541 tcatttggta cgttgaagcc aacataatct gcttcgatat ttactactct tccttcaggt
     6601 ttgtcaagta gtgtaacaat tttgactgat tttgctttgc ggtatttgaa aagatccact
     6661 aaataagcaa gtgttcttcc gctgtcaatg atatcttcaa cgatcaacag atcgcgacct
     6721 tctacattcg tatctaagtc tttgacgatt tttacttccc ctgacgagac tgttgcattc
     6781 ccgtagcttg aaacatccat gaaatccaat tccaaatacg tatcgataga acgaacgata
     6841 tctgccatga atggtaccgc tccttttaag acacctacta ctaggggatt ggtgttttgg
     6901 taaatttctg ttaactcttt gcctagttct ttgcaacgaa cttgtatctc ttcttgtgag
     6961 atcaaaattc tctcaatatc cttttccaac atcaggttct ccttccaatt gcttcttttt
     7021 gatatttgta aagaagtatg tagtgtattt tatcagtttc ttcacgaata ctcaaatatg
     7081 aaaaggcaaa aggtatcaag ctatatatat ttcttttggc atctgtaatg atccaagcat
     7141 gctgcctttg tgaattaggt actttctgat cgataaaata tctagatact ttttttgtga
     7201 gattctctgt taatttaatg cggtctcctg cttttctttt ttcgacatac agttgcacat
     7261 cagcaggaat ccaaatgtca tgagaaaata gagaccatga atctgttgct ttgatgtccc
     7321 ctgcattttc aggtttgacc agaccaatcc attctgtttc attcaaatat attccttgtt
     7381 ctggaatcag caacaagcgc tggtcttctg tctggctagt tgcttgtttt tcttttttag
     7441 agagtacaac aaaatgatac tctcttttca gtatccaatt attgccaata ctgagttgcc
     7501 attggctttt tttctgttgc cactggtcta aaatcgactc catttgttgt tctttcaaaa
     7561 taattcctgt ttttgagaat gctttgtcga aaaaggagta aaaaaaatag tatcgttcag
     7621 catctgtcat ttcttcaatc atttctgcag aaaatcgaaa ttgttcctcc cactgttcga
     7681 cttccttttc gatcaactgt cccatatatt tttgaatgac ttggtctgcc cattggatct
     7741 gttgcgaaaa ttgctggaaa tgtctcaacg cctgtgtatt ttcttgtttc aattgaggaa
     7801 ctaccaaatg acgaagccga tttctctgga tatctaacaa ttggtttgtc tgatcctcaa
     7861 agtaaacaag ctgcgattcc gctgcataag tatataggtc ttctttgcta aaactcagca
     7921 acggacgaat cagtctgccc gtagcaaatg gttgtacttc tttgattcca gaaaaagtat
     7981 ttaactgtcc cccacgaacg attttcatta acaccgtctc gatttgatca tctccgtgat
     8041 gagcagtcat caacgtgtca tattgtcctt cttccatcac gcgagtgaat tcttgataac
     8101 gaaagttacg agcttctgtt tctatggcgg atttggctgg atcttcccaa atacttacat
     8161 ataaagggag attcttctct tcacaatatg agcgaagata ggcagcttct tctgctgatt
     8221 cttctcttaa ttggtgattg atgtggacga tacctaaaga aaaaccgatt tggcgttgca
     8281 cttgtaaaag taaatggagc aaaaccatcg aatcaacacc acctgatacc gctgctaaaa
     8341 ttctcgatcc ttgttgccag aatccttgtt cattcccgtg ccgaataaat gactgctgta
     8401 atagcggtgc ttttttcccg cctttttcaa cgttcatcct ttccacaccc tttcttccta
     8461 aaaaaaagag agcgggaaaa cgtctaaaac gacaattaac ctgccctctg ttgatactat
     8521 gacccaaata gtcgcactat cattatttgc ggctttttag ctgcgacgtc cgccacggcc
     8581 accgcgcttt ccttctgtgt ttcgcttcaa tgaagataag cggtcatcgc tatctttcaa
     8641 aaatgaactc atcaatgaat cgaagtcttc tttttgagct gaaggttgac tgcgagaaaa
     8701 agattttttc tgtgctggac gatttcggtt gtcacgggga tctttttgtt gatatttttt
     8761 aggacggctt tcttctccag attcagcagg ttgttcctgc gctttccgga tagatagtcc
     8821 gatttttcca tcatcattta ctgaaataac tttaactgtt acttcatctc ctacacttaa
     8881 aacatcatgg atgtctttta catagccatt tgacacttcg ctaatatgaa ctagacccgt
     8941 ttttccagca cctagatcaa taaacgcacc aaaatttgtg attcctgata cttttccttg
     9001 cagttttgct cctacctcga ttgacataaa aaaaatgttc ctcctaatta tttccctttt
     9061 ttatattcct gcttattttg cagttgtaga actagttgat tgatctgttt catttgtcga
     9121 gctgtctgta tttgattcta atataggata aactttttca ccgtcttttg agtaaaagaa
     9181 tttgcttctg gcaagtttag ctacatactc atcatctttc agcaatgaaa catcttggtg
     9241 cagctgatca acgtctgcgt tgacttcttt catttcagta tttgcttcga ctctcaattc
     9301 gttcaattga tgcatccttt gcatgtcatg gaaaatctgc acacctatta tcgcgaaaat
     9361 gaccaaagca ccaacaaaaa ttgcagccag tctgcgtctt cgaaaaatca gttgacgttg
     9421 ttgttgctga aattcagcat actttttctt tgcatattcc gtatctagcg cagcgatttt
     9481 attgcttttt ttcgtcactt ggattcgctc caatcttttt gattgtcttt ttcattatac
     9541 caatatcgtg aaagcttgtc taatctattt ctctagtgtt tctgtgcgat tttcagaaat
     9601 aatttcgtac attttttgtg catcttcttt tttggttgat tcatgtaatt ccgtaatttt
     9661 cacttccaac gttttgttgc caaactggac tttcaaaata tcgcctactt tgacatcact
     9721 ggaagatttc gccaatttac cgttgatttg aattcttcct ttatcagcta cttcttttgc
     9781 tactgatcgt cttttgatga ttcgggaaat ttttaaaaat ttatctaatc gcatatctta
     9841 ttcctcactt tttaattttt ttatttaatc gcaggatttt cttaccaaaa ggcaacatta
     9901 gccattctcg tactgtaaac agacgaagac gaatcactgc ataaatgaac acagaagccc
     9961 cgatcccaac tcctatcacg ctgacaaaaa aagcagtgga acgatgagtt acaggaccaa
    10021 atactatatt caatacacca taatacagca gcagtactac tgtcatacaa agaaggctga
    10081 acatcaactt ccgtccaaaa tgccgttctt tccaaaaagc atttagctct tttgtttcaa
    10141 ttcgaacaaa ataccaaagc gtcacaccta atcctaaaag ggtagacagg cttgcacctg
    10201 ctgttcctaa taaaccggtc agaaaagaag tagtcaatcc ttttaccaat agtccccatc
    10261 ctgcgccttt taaagaaggg cgaaacgagt tcttgctttg agcaatactt tgataagctt
    10321 ggatgactgc agtgaaagca atggaaaaaa caaataatac aagcgctgca tttcccgcat
    10381 aatctttaaa caacgcataa ttgatataag ggagcagcaa ggctaatccc aaagacgcag
    10441 ctaatgctaa agcggtcgtc aatctaagat agattttggc tgtctgtaaa aactgacgat
    10501 agatccggtt ggtcaaatga cgagtcaacg caggcaggaa tgtcgcactt aatgcagtgg
    10561 caatcactaa acctaattgt actaaaggct gacctcgatc atagacccct tttgctatct
    10621 tcgcaccgta ttctgacagt ccgtaaactt ccaaagcatt ttttacaaag aaagagtcga
    10681 tcagctggaa aaagataagc aatccactat aaatcgaaac cagtccgcct tctaccagaa
    10741 aacgccggat caagggcttt gacggctgtt tgaacaatgg aaaccgtcgg aagcttaacg
    10801 ctcctccatg aatcttttgt tcatagtagt gaaggatccc atatgcgcat aaaccgccaa
    10861 aaacagctcc actcattgct gccgtccctg tttggtacac cgtccatcca agctttctaa
    10921 aagcaaacgc actacagaca atcacaaaaa cacgaacgaa ctgctcaact acttgagaaa
    10981 cagcagttgg ttccatcaag aatcttcctt ggaaattccc tcgataaaaa gatagaccag
    11041 gcatcagcaa aaaggtaaag gaaactactt ggatcagcgg tttcaattgt atgtctccca
    11101 tcatccaagc aatccagctg ctaaatgcaa agacaaacaa ccacaaaaag acacctgtcc
    11161 aaaatactaa gggataaaga ttttgcaaag cttgctttcg ctcgaaagga ttctttcttt
    11221 ctgcaacgta ctttgatatg aactgcggaa gaccggataa agctaaagtc attgctatcc
    11281 cataaattgg ataaacttgc tgataaacat aaaaaccttc gtcgccgact aagttttgga
    11341 ggggaattcg gtaaagggca cttaatactt ttgctatgaa agaagcaatc gtcaatacaa
    11401 atgctccttg catgacgcgc cgcatttctt tatgatccaa atcattgctc cttcctacgc
    11461 tgacagatat ttttgctcac gcaacgcttt gacaaacttt tggatttcct gaagccatac
    11521 tgcttcttcc atttggttgg ggatcgtcaa gcgtatcacc atctgttctt tttcaacgcc
    11581 tagactggct tttagttttg tcgctgtcag tgcttcgaat aactgttcca cactatagcg
    11641 ttttgttcca actttactta gagtaaagac tatatgcgcc tcctgtttcc ttatcgtttc
    11701 taggagcgct cgatcgccat ccattttgat ctgcccaatt gtcaagagat gtgctacttc
    11761 ttctggatat tctccaaaac ggtcgagcag atcatcttct agttcatcta gcatttcttg
    11821 cgaatcaagt tcacgaattc gtttatagat ctcgattttc tgccgttgat ctgccacgta
    11881 tgtttcaggt agatacgcat cgacaccgag gtcgatctca acagtggtct tctccacttg
    11941 actattcttt ccttgtttac gagaaacagc ttcgcttagc atttgagaat acatatcgaa
    12001 accgactgca tcaataaatc catgctgctg agcacctaag agattacctg caccgcgaat
    12061 ggaaagatcc cgcatcgcaa tcttgaatcc agatcccagt tctgtaaaat ctttgattgc
    12121 ctgaagacgt ttttcactga cttcgttaag gatcttctgc tgctcataca taaagtaagc
    12181 atatgcgaca cggctgcttc ttcctacccg ccctcgcaat tggtataacg tggataatcc
    12241 catataatca gcgttctcaa cgaacaacgt atttgcgttc gggatatcta ctcctgtttc
    12301 aatgatggtt gtagtgacaa gaacatcata ttgaccttca ataaattcaa aaagcgtatt
    12361 ttctaattgc gcctctgtca tttgcccatg agcataaccg atccgtgctt ccggaacgag
    12421 ttcttggatt tcttctactt tttgttcgat cgtttctacc cgattatata aatagaatac
    12481 ttgtccacct cgtcccattt ctcgatggat tgcttcgcga atagccccag gatttttttc
    12541 cataacatac gtttggatcg gataacgatt cgcaggcggt gtttcgatta ctgaaagatc
    12601 ccgcacgcct aacatcgaca tatgcaaagt tctcggaatc ggtgttgcag tcagagtcaa
    12661 aacatccact tgtgcacgta actgtttcaa tcgttcctta tgttttacac caaaacgttg
    12721 ttcttcgtca atgatcagta gacccaaatc gctaaattca atatcttttg acaaaattcg
    12781 gtgggttcct acaacaatat caacttgacc tgtacgcagt tgttcgatgg tttctttttg
    12841 ttgctttctt gttctgaaac gacttaatag cccgatattt acggggaaac cttcaaatct
    12901 ttccagcatc gtttcatagt gctgctgtgc caagatcgtt gttggaacta aaaaggctac
    12961 ttgtttgctt tcctttatcg ctttaaaggc cgctcgaagc gctacttctg ttttcccata
    13021 accaacatca cctacgagta gtcgatccat tggtttttct ttttccatat cccgtttgat
    13081 ctccgctgca cttctcaact ggtcatcagt ttcagagtag gggaaggcat tttcgaattc
    13141 tttttggtag gcgtcatcag gtccaaaagc atatcctttt tctgactctc ttgcggcata
    13201 taatttgatt agatcgtcag cgatatcctc gatttttgaa gagacttttc gcttggtttt
    13261 cgtccattca cttccgccta gcttattgat gcgaggcgct ttggcttcag aggcgacata
    13321 tttttggatc agattcagtt gagtaacagg aataaacagt ttgtcgtcgt tttgatacaa
    13381 aatagtcata tagtcttggt gaacgccatc tacttctagc gtttccatcc caatgtattt
    13441 cccgatacca tgattggcat ggacaacgta atctcctgct tttaactcat tatagctttt
    13501 caatcgctct gcgtttgtta ctgtttgacg tctcgtttgt tttttcgtcg ttttttggaa
    13561 aatttctttt tctgtgatag ctactatttt ttcttgagga agttcaaaac cagcctgcaa
    13621 agctccttca actaattgta cctgtcctct gatcaatgca tttttttctg tttctactac
    13681 taatatgtct tcatctcgaa gcatttgttc tgctttgcgt attctgtcct ttgtcggaat
    13741 aaagatcaca acagtctgtt tttgcttgcg ccaacggtcc atttctgttt tcagcaatgg
    13801 catttgtccg aagaactgtt gcatcgtccg atattgaaaa ttatggattg cttggaaacg
    13861 aagatttccc atcccttttt ggaagagtga gaaaaaggtt gtggtgaact tttccttctg
    13921 cacgattttt tgtatatctg ctgaaaatgt ctgctcagaa aacacccgca attcgctgat
    13981 tttttgagtc tgccattctg ccgcttccct ttcgatttcc cgatttgttt ccatgattcg
    14041 ctgataatca tcaacgacta gtaaactatt tgaagggaaa taatccaaga tcgtcacaga
    14101 ttcttggtaa agaagatctg agtagaattt tgcttcttct gtcgggacac ctgcttgcca
    14161 gcttgaagtc agctgaccga agtaatcttg caaaaactcg cggtctgctt cttctgtggt
    14221 cgcagcaagc cgtttttcta gcattttttg catttgctct attccatgtt ctagatcctc
    14281 tggtccgtag acttgttcac tcgttgggga aacccagatt tcttccgttt tttcgattga
    14341 gcgttgtgtt tctgcttcaa aataccgcat agaatctatc tctacatcaa atagttctac
    14401 acgaacagga taggttgtcg ttaacgggta aatatcgata atgcttcctc gaatactgaa
    14461 ttctcccggt tttgcgacca tctcttctcg tacatagccc atcaaagtca attggcgagg
    14521 aagattttcc acgtctatct catcaccaat atgccaattc aattgcgcct gtagccaagt
    14581 tttcttattc ggcagtcgtt tgtgcaaaga tgcgactggc aacaaataga tacctgcttt
    14641 tttttcttga agtgcgttaa gcgttgcaac tctctcgcct cgcgcttctg gagaagaaaa
    14701 ggccatttca gcagaaagca cttcatccac tggaaataaa tggatctgat cttgcggaat
    14761 cacatgttgc agatcttctg ctaactgatt cgcataatac aaatttggca tcagaataat
    14821 catgttttta tttgttttct taaacgctcg agcaaataga agtgttttcg ctgagcccgc
    14881 taatcctgtg attagttgtc taggcatttt ttcttctaaa ttgctgaccc attcttttac
    14941 ttgcggatct tttccgacta attgaataat atccattcct tttcctcctt cctcaattga
    15001 atcgattcat cgcatccacg aacgaatgcc cttctatgag atattcgact gctttaacag
    15061 attgacacat gctttcttct atcaaaggct gattttcttt gctgaaagga ctaagcacat
    15121 gctggactac tgtttttttc ccttctggcc tgccgattcc caccttgatt cgatcaaaga
    15181 cattcgtatt caaatgggaa ataatacttt tgataccgtt atgcccgccg gcacttccct
    15241 tttgacggag ccggattttt cccactgcca gatccaaatc atcgtagatt acgactaatt
    15301 cctctggata aatcccaaaa taagtcatta gtgggccgac tgcacgacca gattcattca
    15361 tgaatgtttg tggtttgact aaaaggatct tttctccatt atgaaaaaat tcggcaactt
    15421 ctgcttcgaa cggatttttt ttgaaagtag cttgatgctc gcgtgcaatt ttatccacga
    15481 ccataaagcc gatattgtgt tttgtatatt ggtatttggt acctgggttt cctaacccga
    15541 cgatcatttt catttttgtt ttccacctaa ttctaaaaag cagcacaaaa ggctggactg
    15601 ctaattagcg gtccagtcca tcgagctttt ttctttttta cacttgtcaa tgcatagtat
    15661 aacacaaaac aaggcgtttc ggctaaaaga gaatcgttaa taaatgataa agaaattaaa
    15721 aatttcttca aagtttaatg aaataattga tatataaaaa tagtgaaata acgcacatgt
    15781 aagcttttac atataataca accttgttat ctgttatatt ttatagccaa atagcgtgac
    15841 atggggcttg agaaatgtta gcataagcat gggaaaaaac aaatcaatgg aaggattgat
    15901 actaaatgac tgcagctgca gaaaaaaaag atcatcaaaa agttattctt gttggagacg
    15961 gcgccgtagg ttctagctat gcctttgctc tagttactca aaatatcgct caagaagtag
    16021 gtattgtgga tatcaatact gctaaaactg aaggagacgc aattgacttg tctcacgctt
    16081 tggcatttac ttcacctaaa aaaatctatt ctgctactta cgcagacgca catgatgctg
    16141 acttagttgt tattacagct ggcgcaccac aaaaaccagg tgaaactcgt ttagacttag
    16201 taaacaaaaa cctaaaaatc aaccgcgatg ttgtcacaca aatcgttgaa tcaggattta
    16261 acggtatctt tttagttgcc gctaacccag tagatatttt gacttactca acttggaaat
    16321 tctcaggttt ccctaaagaa cgcgtaatcg gttcaggtac ctctcttgac tcagctcgtt
    16381 tccgtcaagc acttgcggaa ttagttgacg ttgatgcacg taacgtccat gcttacatct
    16441 taggtgaaca cggagattca gaattcccag tttggtcaca tgcaaatgtt gccggcttgc
    16501 aaatctatga atgggtaaaa aacaacccag aaatcgatga agaagctatg gttaacctat
    16561 tctttggcgt acgtgacgct gcttacacaa ttatcgagaa aaaaggcgct actttctatg
    16621 gtatcgcagt agcattagca cgtatcactc gtgccatctt agatgatgaa aatgctgttc
    16681 ttcctttatc agtattcatg aatggcgaat atggattgaa cgacatctac attggtgcac
    16741 ctgctgttat caaccgtcaa ggtatccaaa aagtaatcga aattccttta agtgacagcg
    16801 agcaagaccg tatggctgct tctgctaagc aattaaaaga aattctagat gaagcttttg
    16861 ctaaactaga cgctgaataa tctttgaaca tgacggaaaa catctattcg gtgttttccg
    16921 tttttttatt ttatcaccct tatggtttct aaattttttc ataaagtaga gataaccttc
    16981 gtcttttcct ctaaattatg ctatcatgag accgttccac cctaaacttt tacttaagga
    17041 gttgtcgata tgacaagatc ttcgcatcga aaaaaatcga aacatgttgc tttgctttca
    17101 gttcttggtg ttctcttagt gctgatcagc ttttatacct atcgcagtac atactacaca
    17161 aagcattttt tgccgaatac agaaataaat ggaataaatg tcagcaatct aacagtcgaa
    17221 aaagcaaatg aaaaattaaa agaagcttat tctgataaaa aactggctat taaagaagat
    17281 ggaaaagtct ggcaggaagt accaaaatcc gagctcggct acaaagatga tttcacttcg
    17341 gagctttctc cgatcctaaa tgaacaaaac ggatggactt ggggaatgac ttatgtctca
    17401 gcggcagaaa aacaagaaat agatcctgtc agtcaaaacc accaaaaact agacactacc
    17461 gttcagacat tgacaactaa gctgactgat ttgaacaaag accggacacc tactactgat
    17521 gcaacgatcg aaaaagcagg tgactctttc gttatcaagc ctgaagtcaa tggaaatacg
    17581 atcgacgtcg atgctgcggt caaacaatta aaaagtgcgg taaactctgg taaagataca
    17641 attgaattga ctgaattcaa agaaaaacca aaagtaacat ctgaagacag ctcactgaaa
    17701 gaacaactcg catccatgaa tgctatcgca aatgtaaaag ctacttacag tataaacggt
    17761 gagactttcc agatcccatc aagtgatatt atgagttggc tgacctacaa tgatggaaaa
    17821 gtcgatttag atacagaaca agtacgtcaa tatgtaacag atttaggcac aaagtataac
    17881 acaagtacga atgacacaaa atttaaaagt acaaaaagag gagaagttac ggtcccagtt
    17941 ggcacttaca gttggacgat ccaaacagac agtgagacag aagcattgaa aaaagcgatt
    18001 ctggcaggcc aagattttac tcgttcaccc attgtgcaag gtggcacaac cgctgatcat
    18061 ccattgatcg aagatacgta tatcgaagtt gatctggaga accagcatat gtggtattac
    18121 aaagacggaa aagtggccct tgaaacagat atcgtttccg gaaagccaac tacacctaca
    18181 cctgctggag tcttctatgt ttggaataaa gaagaagatg caactttaaa aggaacaaat
    18241 gacgatggaa caccttacga gagtccggta aactactgga tgccgattga ctggacaggt
    18301 gttggtatcc acgattcaga ctggcaacct gaatacggtg gagacttatg gaaaacccgc
    18361 ggttcacacg gctgcatcaa caccccacca agtgtaatga aggaattatt cgggatggtc
    18421 gaaaaaggaa cgcctgtatt ggtcttctaa caaaaataat atataaaaag aaagcacccg
    18481 tacgattggt acaggtgctt tctttttatt atctaacaat gtgctactta catttcagca
    18541 gcagtaaaga cttctgaaac atcatcatcg tcttctagct tatctactag acgttccaat
    18601 tgctcttttt gttcctcatt taaatcaatc gtcgtttgtg gaatcatcgt caattctgct
    18661 tgcgccaaag tgaactcttt ttccaactca tctcgtacag cagcaaaatc ttctggtgca
    18721 gtataaatct cgaatacttc aggagaagtt tgcagatctt ctgcccccgc ctctaataca
    18781 tcctcaaaca tcgtctcttc atcaacagtc aacccatcgc gttcaatagc gatatatcct
    18841 ttgcggtcaa acaagtaact gactgaaccc gtttctccca gtgatccacc gtttcgagta
    18901 aaagctactc ggacatttgt cgctgtccga ttacggttat ctgtcaatgc atggactaag
    18961 attcctactc cacccggacc atatccttca tacgtgattt catcgtaatt cgtttcatct
    19021 acggcactcg tagccttttt aatcgcccgt tccacattgt cgttaggcat atttgcagct
    19081 tttgctttgt ccacaacaag ccgcaaagct ggattcatag atggatcagg accgcctgct
    19141 ttagctgcca tataaatttc acgagaaagt ttctgaaaga ctttccctcg ttttgcatct
    19201 tgggcatttt ttcttccttg gatattatgc catttactat gtcctgacat gatttttcct
    19261 cccttgttct tttgagaata cacttctatt ctagtactat ttcacaaaaa aacaaagcca
    19321 cagccaatct ataaacgctt cttgaatgcc gcaaaaagca cacataatat cacagcagtc
    19381 agagcaccga tcgaatccaa catgacatct tggaacatag gtgttcgtcc accggtcatc
    19441 atctgatgga attcgtccaa acctgcgtac cctgttgctg aaagccaagc aaggatcgct
    19501 gtcagccacc aaatttttag cttggggaaa acacctaaaa acaagctgcc tcccaaaata
    19561 aaataggtac cgaaatgtgc gcccttcctt aaaaagaact ctaaaaattt ggcgtagccc
    19621 agatggttga tactcaccat acttccacca taattaaaac gtatacccgc taatgtgtct
    19681 ttaaatggct gattaggcag ccagctttct aatcgcgaaa cttgtgattg ctgtccgtaa
    19741 gtttgagaag aactgtaaaa taagattata acgactatca gtgcgattac taaataaata
    19801 tttccgtttt tcatttgttt ttttgaagaa ttcataagtc acctctgtat tttatcttag
    19861 actttttttg aagaaacaac aatcattttc atagagactt cttccataaa aaagtgctat
    19921 acttaatttt gtattacaat atgaagggag ttttttcatg agttattcat taaattggaa
    19981 tctagattct attttttccg gaggcagtca ttctgatgct ttgaaccaac ggatgaagca
    20041 attggaagac caaatgaacg agtattatca ccgcgtaaca aaatggtcac ctagttctga
    20101 caatgcagag cagttaaacg ctattcttca attgcaagaa acgattacga atggttttac
    20161 ccaatgcagc agctatatta ctgcattgct ttctgccaat gtcaatgatt cagatgcaaa
    20221 ggtcttatca ggcaagcttt acgcaatgct gcctcgtctg caatcagccg aaactgtatt
    20281 gtcaaagaaa tttgcagaaa tatctgacaa tgattggaat cagatgcttt ctcaatcttc
    20341 gtttgaaaca attgcttttc gtttaaacga gattcgtcgt gatggctcac aattattatc
    20401 agaagctgaa gaaaacatta taaatacgct ttctttagat ggtctaaatg cttggagcag
    20461 tcattatgat acgattgtag ccagcatttc gattcccttc gaacaagatg gacaagtagt
    20521 cgaattatct gctggacaag ccttcaataa gatgatgggc gatccagatc caaaagtcag
    20581 agaaacactt ttcgcagcat gggaagaagc ctggaaagaa aaggcacccc tcttcacgga
    20641 tactttgaat catttagatg gttttagact ttctgactat gaacttcatg gtgtcacaga
    20701 ttttctacaa aaaccattag agtacaatcg gttgaagaaa gaaacattgt ctgtcatgtg
    20761 ggatacaatc cagaaaaaca aacaacccct tgttaattac ttgactagaa aagctaatct
    20821 tttcggtaaa gaaaaaatgg aatggcaaga tcaagatgca cctattattt taggcgattt
    20881 gaaagaaaaa acctttagtt ttgacgaagc agcagcattt attatcgaaa actttaacaa
    20941 attcagtcca aaaatggcta aatttgccca atctgctttt gaaaagagct ggatcgaagc
    21001 agaagatcgt cctgggaaac gtcctggtgg ttattgtact gagttaccag aaacaaaaga
    21061 atcaaggatc tttatgacct acagtaattc tgttaatgag gttgcgacac ttgctcatga
    21121 actaggacat gctttccata gcagcacgat gtgggattta ccttctttaa atcgcgaata
    21181 tgccatgaat gtcgcagaaa cagcaagtac attcgcagaa ctgatcgtag ccgatgctac
    21241 attaaaagtc gcaaaaacaa aagaagaaaa aatcaatttg ctagatacaa aactgcaaaa
    21301 tgctttagct atgttcatga atatccattc ccgattcatt tttgaaaatc gattctatga
    21361 agcacggcaa gaaggattag tctcagaaga taagatcaca gagatgatgg ttgaggcgca
    21421 aaaagaaggc tatcaaggag ctttagctac ttaccatcca tatttctggg ctgcaaaatt
    21481 gcatttcttt attgatgacg taccgtttta taacttccca tacacatttg gctacctctt
    21541 tagtttgggc atctatgctt acgccaacca aaagggagca aattttgaag aagaatatat
    21601 ccatttacta cgcgatactg cctcaatgac gacggaagat cttgcgaaga aacatttgaa
    21661 tgtcgatctt acccaaccag atttttggca agcaggtatc gacatggtga ctgaagatat
    21721 ccaaacgttc atggaattga cagaagaatt tatctgattt ctattttatc acaataaaaa
    21781 aagagttagt ccagaatggg ctaactcttt ttgattaatc attcttacat gctgacagca
    21841 aagtcagggg caaaccattg aactgaacca acttttacgc tttcgcctgg ttgaggagca
    21901 tggatatatt gtcctccgcc taaagcaatc gctacgtggt aagttccgcc ttgtgacccc
    21961 cagaataaca agtctccagc ttttgcttga gaaactgaaa tttttgttcc agctgattct
    22021 tgaggaactg tccaaccacc gatgtcacga ccagttactt gcatgtaaac atagcgtgtg
    22081 aaccctgagc agtcaaagcc acttggatct ttaccgcccc aaacatatgg agtaccaata
    22141 tatttgtaag cttctgctac gattgctgca ccattcacac ttccagaagg agctggagca
    22201 ggtgttacag gttttggttg ttcaggtgtt ggtgttggcg ttggagccgg agtactactt
    22261 cctgtgccgt ttcctgtatc aacactttga tctgttgatg gtgttgtagg cgcaggtgtt
    22321 gttgattctt ctgttgttga agattcaggc actgttgttg attcttctgt tgctgaagat
    22381 tcaggcactg ttgttgattc ttctgttgct gaagattcag gcgctgttgt tgattcttct
    22441 gttgctgaag attcaggcgc tgttgattct tctgttgaag attcaggtgt tgttgattct
    22501 tctgttgctg aagattgtgt agctgatgat gattcttcag tcattgaaga ttgtgtagct
    22561 gatgattctt ctgttgctga gctttgtgca gtagatgaag cttgagtagc ttgtgcttca
    22621 gcctctgctt gttcgcgtgc ttctttttca gctttttctt gtgcagcttg ttgacgagct
    22681 tgttctgcta gacgttgttg ttcacgaata cgagcttgct ctgcttcagc ttctgctttt
    22741 tgacggttca agtcagcttt cttgtcttca gcagttgctt gttcagcagc taatgaagtt
    22801 ttcagtacgt tcaaatcagc ttgtttagat aaaagatcgc ctttttgaga ttccaaagca
    22861 gcttggtttt cagctaattc ttttagttta gcatcgtttt cagctttttt gtcttctaca
    22921 gcttttttat cttgtttttg ttgttccatc aagtcgttgt ttgcttttac catcgttgtc
    22981 attgcttgaa cgcgtccaat agcatctgct aatgaatcag cattcaatac agcatcgatg
    23041 tagtttgagc ttgtgttgct tacttgtgct tcgcgtgctt gtttttggat tgtatcttca
    23101 cgtttttcaa tacgttcttg taaatctgca atgtctttta ctaattgtgc agattcttga
    23161 cgcaatgtat cttgttttgc taataggtct tgtgcttgtg tgttgatttc agaaacttgg
    23221 ctttctaagg catcgatttg tgattgtgca tctgcttgtt gatttttcaa gtctgcaatc
    23281 ttttgatctt gctgttgtat ctgagaatca aaatcgtccg ccgcggcagc gatcggtgat
    23341 gctacggcag tcaaggtcat tgaacatacc attactgctg atattaaact ctttttcact
    23401 cttcattcct ccgactggct taatttaata aatatctaaa tatatttaag tctttcttaa
    23461 cgatataaaa attgtaccat agcagtgtgt caacgatata atagttatgt tacaaaaatg
    23521 tttcaaaaca acttttaaaa atgacaaaac tgttcgtttc agaaaatgat catgaaaaag
    23581 ccgcgttaag tctagcattt cttaagataa caacgattct ttttcgcttt cgacctaaaa
    23641 ataaaaaaag aaattattca tcactgaata atttcttaaa gggaaaaatg aataatacaa
    23701 atataatcat gttcaacagc agtgtaggtc ctaaaaacct tgtaataaaa tacgtgttat
    23761 ttactactgc taatttaaaa atcaactgga ccaccatcgt aaacaattca taacccgtga
    23821 caaagatgat catactgaaa aattcagtaa agatgttgac atggataacg tctttcatta
    23881 catacatcaa ccatacaatt aaagggagag ctactgcata gataccgata acgccaatat
    23941 agtaagcgtc atagatagcc ccgagaacaa tcgtggtaat cagtaaataa cgtttttcaa
    24001 acgccatact gcaacataat aatgccaata tcagaaagtg ggcatttgac atataggtgc
    24061 ctttcgacca ctcccctagc attcttgtta aatgaccatc tatcaacatc aaaaagaaca
    24121 aaacgattgg cagatagtac ttcattgttt ctttcttcaa catggactaa tcctccgcta
    24181 gccgttggac aatcgtcaca actgacacgt catacatttc tgcataaggt ttcacataaa
    24241 cttcccgatc cagcccataa ctatctggtt tcgttttaat aaccgtaccg atcggcaagt
    24301 tagctggaga attccctcca agaccggatg tctggacaac atccccttct ttgatatccg
    24361 tatcaccagt taattgggtc accactaagg catggagctt ttcatcatag tttttaagca
    24421 aaccaaacgc ttcgccatta gccgaagata cccgtactgg aaaatgattg gagctttcat
    24481 tagaggatga cagtaattcg attttagacg aagccgtatt gacctcgatc actcggccaa
    24541 tcaatccttt ttgcgacatg actgccatat ttgcttcgat accgtcttta gaacccttgt
    24601 ctacgatcag catgtcctgc caactgtcag gcgaacgagt aatgacattt gccgttactt
    24661 tttcgtaact agtcagcgtc tgattcaact caagttcttt tttcaacgct tcgatttctc
    24721 tctcgtaatt cttgttttgc tgtgaaacgt catcatagct atcgattttt tcttttagcc
    24781 gctcattttc ggcataagtt gaaaaaagat tatggacaga atctactcca tttcgtaccc
    24841 accgtactgg ggcagagatt gttttatcaa ccattgcaac actgtcatta acgatggatt
    24901 ggaagaaatt gggctttcct tcattcgctc gctgcgcagc ggtcacactt agtatcgtca
    24961 ccacgatgat aacaataacc aaggtaataa taatattttt attaggattg aacttcttca
    25021 caaagacacc tcgaattaat tagactcttg tgttcaattt tatcactaaa tgccgtgaaa
    25081 caaaaggtaa gttgctcctc ttaagctttt ttttagcaaa taatagattc tgtcattttt
    25141 agcctgaaag acaaattttt ttatttgttt atggatcaat ctttgctttg aataactgca
    25201 atcataccat ctgaaaaaga aaattctgcg gtatctgaaa gaaattcgtt acttgcataa
    25261 gatgtcggat attctacttc tttattttcc aatacatact tgctgccttt taatgtaaga
    25321 ttcgagacgg gagtcaagca gcaataagct aaatacttca tatctggtat ctgtcttact
    25381 atatgctctc caggcaaata ataagacaaa taattttgac aatctctgat aataagctga
    25441 tgggcaaagg gtttgaagcg aggttccata cctaaccaga gattggctaa aagatgatcc
    25501 aatcttccgc ccgtagctcc aatcaaagtg acttccgctt gcgggtaacg ttcaaatgtt
    25561 tttaagatac ctaactgtgt atctgtatcg tctttttctg caggggaacg ggtatactct
    25621 ttggcttttg caaatacttc cttctgctct tcgttcgaca atgaatcaaa atcacccact
    25681 gccagatcta ctgggtagcc tgcttgaagc aggtacagcg caccacggtc tatcccgaca
    25741 taggcatcgt atttggacag cagagactgc ggccagtttt gcggattacc tccagcagct
    25801 aataaaattt tcatttagtc taatgcctct tttaatcgtt cgatttgtcc gactggattt
    25861 tcggctccat agatatatga tcctgcaacg aagacatccg cccctgcatc tttacagatt
    25921 tttgctgttt ctggaacgat tccgccatct acttcgattg cataagtcca attgttctct
    25981 ctacgtagat cagcgagttc cgtaattttt tctactgttt cttcaataaa gctttgtccg
    26041 ccgaacccag gattgacagt catgactagt acttgatcag ccaaaggcaa aacatgtttg
    26101 atcatggaga ctggtgttcc tggattgata actactccag ctttaactcc taagcttttt
    26161 gtcatttgaa gtgcccgatg aatatgagga gttgcttcga cgtggacagt aatgatatct
    26221 gctccagctt ttgcaaatgc tggaatgtag ttttctggat caacgatcat cagatggacg
    26281 tctaacggta atttagtaac aggacggatt gcctgaacaa tatttggccc taatgtgata
    26341 tttgggacaa atcggccatc cattacatct acgtggatgt aatctgcgcc tcctttttcc
    26401 actaactcaa tgtctctttg taaattggca aaatctgcac tcaaaatgga tggtgctatc
    26461 ttcattcttg tttcctccta ttttcgttta ccttcttttt ttgcatacat tggttttctt
    26521 ttttcgattt cttgtaagaa ttgcaaataa ttgtcgtaac gtgtctgtgc gataccacct
    26581 gtttctactc tatgttttac ttcgcagcca ggttctttag catgcatgca ctctctaaat
    26641 ttgcaatgga cagaagcttc tacaaattca ggaaattgtc tcggcagttc tcctgcttca
    26701 attgtcaaaa agtcaatcga gctaaatcct ggtgtatctg ctactaaccc gccatagata
    26761 ggaatcagtt ccacatgacg tgttgtatgc cgtcctcttc caagtgcatc agaaatctct
    26821 cctgttgcta aattcagttc cggtgatatt tgattcagta gcgtcgattt tcctgctcca
    26881 gactgaccca taaagaccga tagccgttct gggaagtaac ggatcagttc tgtcgtatca
    26941 cccgtatgat tgggtacaat caccggatag cctattttag tataggtttg cttgatctct
    27001 tcgatttttt ctgggtcgtc tgacaagtcg gtctttgtca aaaaaataat cggttcgatc
    27061 gactcgtatt ccaaggtaac tagaaagcgg tcaagtagat tataagaaaa tgcaggctct
    27121 acgatacttg tgacaatgat tccaagatca acatttgtga ctggtgggcg aactaattga
    27181 ttttttctcg gcaagatttc cagaagatag ccgtctgttt gattttcact ctcaaagatc
    27241 acctgatctc cgacaagcgg cgtgattttc cgattccgga aatttcctct tcctcttgtt
    27301 tgataggtct ctccgtttgc gtatacatag taaaaaccgc tgattgcttt tctgatttgt
    27361 cctttgataa gtgccacctc cgtttttgtt tattttacca tacgaagagg aaagtaggtg
    27421 ttattccatg caaacttctc aaagtatatg gcttgaaaat tgatcaaaag agatagaaac
    27481 acaaaaaaga gaatgcaaca aatcaatgtc gcattccctt ctgatatatt ttattcagca
    27541 cttattttga actttctgag gtgctagctg atgaacttgt ggagctggaa gattcttctt
    27601 ttgaagagtt gcttgtgcta ctggagctac ttgagctgct agaactgtct gaagagtctt
    27661 tttcagaact agaagacgct ggatctggtc ctttagagta aattacgttc acaaccattc
    27721 ctttggtaat tgtcgttcct gcccctggta ctgtacgaat cactttatct ttatccaccg
    27781 tgtttgaata ttcggaagtc tcatgcccga tatattctgc accgacacta gctaaataac
    27841 tttgtgcttc gctttttgta tagccggaga tatcattcaa tttaggctct gttccttggc
    27901 ttacgacaaa attgatgtaa gtttcttctg ctacaacttc acccgaggct ggatcctgac
    27961 tgatgatcga acctgatggt acagtgtcgc tatagtcata agtagcacta atattattga
    28021 tattgaatcc ttgtgtaaca agccaattac gaacagtttc gtagttttct cctacatgac
    28081 tactcaaagt cactgtttct ggtcctttgc tgactgtgaa agtaatcgtg tctgttttag
    28141 gatcgacttc tgtatcttct gatggagatt gcgaaatgat cattccgctt tctacctctg
    28201 aactgaattc ctcttctttt tgaatcaagt cagcagaaaa ccctaattct ttcaaacttg
    28261 cttcggcatc ttcataactt ttaccactgt aatcatctaa tttgattttt ttcgtgccgc
    28321 tactaatata cagagtgact tcgcgttttt gcttgactgt cgttcccgct gccgggtctg
    28381 tcttcactac attaccttct tcgattttgt catctgcaat ttcttctgtt tttgttgcta
    28441 cttctaattt cgcttttgcg agtgtttctc tagcagaagc ttcagaaaga tcagaaacat
    28501 caggaacaac aacttctcct cgcccgccag aagcaaagaa tacagctgtt ccgattccta
    28561 aaacagcaag aatagctaat aggatcagcc accatttttt ctgtcctttc tttttaggat
    28621 caggcagaac ttcttcctcc tctggtaagg tttcgttttc tggcttgtct tttggcagag
    28681 gcatagattt gaatgaatca ggcattggtg catcttccgt aaggggtgtg ataacttttg
    28741 tttcattatc catcacatga ggctgccatt tttcttcgtt tgcacgagct ggtgataata
    28801 ctgtagaaag atcatcagac atttcctcgg ctgacttata acggtctgca ggttctttag
    28861 ccgttgcccg taaaatcacg ttttccagtg cttgtggcac atttggatca agtgctttta
    28921 tagatggaag atcatcttga aaatgtttta aagcaattgt tacagcagat tcaccatcaa
    28981 acggtacgct acccgtcaac atctcataaa ggatgatccc taaagcataa atatctgact
    29041 gcttcgttgc catacttcct ctggcctgct caggggacag ataatgaaca gatcctagca
    29101 tcgtattcgt ctgcgtgatc gatgtttcag ataaagcgat agcaatcccg aaatccgtga
    29161 tttttacaac accttcatta tcgatcagta cgttttgggg tttcaaatct cggtggatga
    29221 tttgatggtt atgagctaaa gaaatagcag aaaggatctg ctgcataata tttactgctg
    29281 tttcataagg aacaggataa tgtgtttgga tatatcgttt caagtccatt cctttgacgt
    29341 attccatcac cagatactgc atgttgtctt cttcaccaac atcgtaaaca ctaacaatgt
    29401 ttggatgaac gagttctgtt gctgctaaag cttctctctg aaatcgtcga atcgcagtct
    29461 ggtcattttg aaagtcaaat cgtaagactt taactgctac atcacgatcc aagattaaat
    29521 cgtgcgccaa aaatacattt gccataccac cgctaccgat atttccagtg atttgataac
    29581 ggccatttaa ttttttgccc aactcgatca tacactgtcc tccttatatt cgataagaag
    29641 aacggtgata ttatccgctc cgcctgcttc attggcacga tcaatcagct cagttacttt
    29701 atgagacaat gggccttctt gattgatgat cgttcctatt tcttcttcag acagcatgtt
    29761 cgtcaagcca tctgaacata acagcagtcg atcttttagt tgccaaagat gagtagaaac
    29821 atctacttcg actgttccag gcatgccgac agaacgtgtt aaaatatttt tccttggatg
    29881 gttcactgcc atttcttcgc tgatttctcc tgatttgact agttcattga ctaaagaatg
    29941 atcctccgtc aattgcatga ttttatcttc acgaatcaaa taagctctgc tatccccaac
    30001 attggcaatc gtgaaccagt catctgacag agcggccgct acgattgttg ttcccatacc
    30061 gttatattcc ggctgttctt gtccacgctg ataaatcagc atattttctt cttgaatcga
    30121 ttgaatgaac cattgggcga ttttttcatc gtcaacagct tcttgttttt cccaagcttc
    30181 gcctagattc gttaccgcca tctgactggc aatgtctccg gcacgatgac cacccatccc
    30241 gtctgctaat acagcaagct tgagacctga acggctggta aatacactgg catagtcttg
    30301 atttgtgtta cgtcgtcttc ctacatctga ttgatattca atctgcattt tttcacctca
    30361 ttactttttg cgcaaacaac aaatgaaaaa tccatctgtg taaaactgat gcggatacaa
    30421 agtcaacatt ttctcttcga ttgatgattg tagcatagga ttggtcaaaa catcaatcct
    30481 ctcaaaatca gggtgtcttt ccaagaaagc agaaacaacg tcttggtttt cttcttttaa
    30541 gatcgtacaa gtgctataag tcagaatacc ggaagacttt aaagttggtg cgcagctttc
    30601 taaaatttcc aattggattt ttggtaaatt cgctaattca tccggctgtt ttttataacg
    30661 aatatctggt tttcgccgaa gcagcccaag acctgaacaa ggcgcgtcta ctaaaatccg
    30721 atcaaactgc tctgcttcga actgtttact gacttctcta gcatccatct tttgagcgta
    30781 gacagcagaa gagacaccta gacgtgctgc attatcttca atgagtttga ctttgtgttc
    30841 gtgtacatct aaagcgacca cttctccacc gcatgacgga tctaaaaaag aagcaatatg
    30901 cgtcgtctta cctccgggtg ctgcacaggc atctaagaca tgatgttcag gctcgatttg
    30961 catagacggc gctacaagca tcgaactttc atcttggatc gtcatgacgc catcgtggaa
    31021 caatgagcta gaagctaaat gccctttttt cgctactata ccgtatggac tgacttggct
    31081 tttttcagct gtgatctctt cttcttgcaa aacagtgatg gcctgatctc tggaaagtcg
    31141 gcgtgtatct actcgggcac tagcatggct aggctgatat agcgataaac cgagcttttc
    31201 agtttcttcg tatccgattt gatccaccag tcgtttcgtc atccatagag gcaggctgat
    31261 tttgacagaa agtctttcga taggatcagc aatgccttgc agatctggtg ctccttgacg
    31321 ctgataattc ctcaagacac catttacaaa tttccctgtc ccaggatttc cttttacttt
    31381 tgcgatttcg accgcctcgt ttaaaatagc atgtgcaggg actttatcta aaaattctaa
    31441 ttggtataca gaaagataaa gaagcatctt gacccagtca tccacttttt ttgctttagc
    31501 gatcaatggt gcaacgtaaa attccaatag tcgctgatgg ctaatcgtac catagatcaa
    31561 ttctgtaaat aaacccacat ctttttgatt tagctcgctt tgtttgatca tctcattcaa
    31621 caaaagattc gagtaggcgc cacccttgtt cactcgctct aatgtcagta atgccatata
    31681 tcgtactgat tttttcattt ttttagggat ttttttcatt atttcacctg ctgaccaatc
    31741 tgaacttgct gaccgcttcc gttaaggaaa tcatgtacgg cctgttttcc tttaccagct
    31801 ggctgtaatt cattgatggc taagacggtc tgtttaccgc aagcaatcca tagatttttt
    31861 ttgtctttcc ggatgatcgt accaggtgct ttgtctgtag tttctgccaa tacttcaacc
    31921 gataataatt tccagcgtat gccctcatag gtcgtgaatg caattggcca aggacgcatt
    31981 ccgcgtactt ggttgtcaat ttcttctgca gttttatgcc aatcgattgc ttcttgttcc
    32041 cgtgtgatgt ttggcgaaaa agttgcttct gactcgtctt gaggtactgg tttttgtcca
    32101 tccaaaatat tgggcaatgt ttctagcaat agctttcttc ctaaaaggct aagcttttca
    32161 aacatcgtcc ctacatcatc ttgtttagtg attggtatgc tttcttgcgc atagattccg
    32221 cctgcatcca tttttttgat catttccatg atcgttacac cagtttcttt ctccccattc
    32281 atgatggcat aatgaacagg cgcacctccc cgatatttag gaagtaaaga agcatggaca
    32341 ttgattgccc ctaattttgg tacttgcaat aacttttcag gcaagaattg gccaaatgcc
    32401 gcagtgacga tcacatcagg caccaattca atgatttctt ccatttctgg cgaaccggag
    32461 attttctctg gctgcagcac acggataccg tgcttcagag ccgctttttt taccggtgtc
    32521 ggcgtaatta ctcgtttccg cccaactgga cggtcgggct gtgttaccac tgcctggatc
    32581 tcgtaacctg attctatcag cccttcaaga atcggcacag aaaaagcagg tgtgcccata
    32641 aatactagct tagtcatcaa gatgttcctc catatattct tcaagttctt cttccgggat
    32701 ctgctgtatc attttctcaa tgaacaagat accgtctaag tgatcgattt catgctggaa
    32761 ggcacgggct aaatagccaa aagccgtcac ttctatctct tctccgtctc gatcataata
    32821 acgcacggtc acttcatctg ctcgcttgac cgttccatag acatgcggaa tactgagaca
    32881 accttctacg tcaaggcttt caccttttgc ttcgatgatt tctgggttaa tcagttcaaa
    32941 tttctcgcct tcatctactt cgatcacagc aattctcttg ttttgtccta cttgaggagc
    33001 agcgatccct attccgtcat tcgcaatcat tgtctcatat aaattgtcta ataaagcgat
    33061 tgtctcgtcc gtgattacat cgattggctg agcagttctt tttaatttat cattagggtg
    33121 gatcaatata ggatagcgca taatttggcc ctttcttaaa taaagtttaa tggttcgttg
    33181 tcaattgcca caaaaagacc ttgtcgctgt tctttctggc ttccattcaa aatttcatcc
    33241 aaaacatgag gaagattcgg ttcatgttta tatttgatga ttagttgata ataatatcgg
    33301 tttttcactc tcaaaatcat gctgggcgtt ggccctaata gcaagctttg agggcttaac
    33361 acttctttta gctgattggc aatctgaaag attttctttg ccgctacttg ttcttcagga
    33421 tggctggcgg ttattttcac agtaaagtaa taaggaggat agcctccacg atgccgtaca
    33481 tgcatttcct gctgataaaa ctgctcataa ttttgttttt tagccaattc tatggcgtaa
    33541 tgttgaggat tgaatgtttg gatcacgact tcgcctgctt tttccgctcg ccctgctcgt
    33601 cctgaaactt gggtaagcaa ttggaatgta tgctcactag aacgaaaatc cggtaaattc
    33661 agggaggtat cagcattcaa caccccaact aatgtcactt ctggaaagtc caaaccttta
    33721 gcaatcattt gtgtccctaa taatatatct gcttcttttg caccgaattt ttgtaaaatc
    33781 tgttcgtgtg ccccttttct tcgagtggta tctacatcca tacgcaaaat cctagcttgc
    33841 ggataaagtt ctcggagttc ctcttctact ttttgagtac ctgttccata gtagcggatt
    33901 ttattgccgc cacaattagg acagcgattg ggaataggtt cttcatgtcc gcaataatgg
    33961 cagcgcattg aacgtgtatc catatgcagt gtaagagaga tatcgcaatt aggacatgga
    34021 agaacaaatc cacagtccct acacatcaca aaagacgaat atcctcgacg attgagcagt
    34081 aggacagttt gttctttttt gtctaatcga ttttgtattt tttcctgcaa attagcagaa
    34141 aaagtagagg tccgatgatt ctgaaactct tcacgcatat ctacgatctc aatagctgga
    34201 agctgtgcag ctgctttggc tcggtggttt aactgcaata actgataaac gcctttttga
    34261 gctcgtgctc ttgattctaa agagggcgtc gcgcttccta gaactattgg gcaatgatga
    34321 tatttactgc gccaaattgc tagatctctc gcatgataac gcggtgtctc atcttgtttg
    34381 taacttgatt catgttcttc atcgataatg atcagcccga tatttttcag cggggcaaaa
    34441 atagcagatc gtgcgcctac tactacttgc gcttcttccc gctcaatctt gcgccattca
    34501 tcatattttt caccttggga aagtccgcta tgtaagaccg caactgattc tccgaagcgt
    34561 cctttgaatc gctcgaccat ttgcggagtc aatgcgattt caggcactaa cataatagcc
    34621 gttttatttt ctgacaaaac atcagcgatt gcctgaagat atacttctgt tttcccgctg
    34681 ccagtgattc cctccagcaa aaagacctga tctttttgct gctgacctgc tgtgatgatt
    34741 tgttcgacag catttttttg ttctgcattc agttccaatg ccgtcgtttg gtcaaatact
    34801 cggtctttat aagggtcgcg ataacgttct gattctataa actccagcca gcccttttct
    34861 tttccttgat tcaagacagc agtactgatt cctttatttt tgaaataagc aattggttct
    34921 tcttggctca gttcagataa acacaaaaga agttcttttt gtttcttggc attttgccgt
    34981 aattttgccc attcttcttc gatttgcttt tcagttaaca aagaacggac caaacgaatc
    35041 gtttttactt tatttcgtgt atggacttca tatttgatat ctactaattg ctcttggcgc
    35101 cagcgaatca attgagaaag gctgccttct tcttctgctt ccttccagga aatcacttct
    35161 cgctgatcaa acaatacctg aacttctggt gtgtctgcca aaggatagat caatttatca
    35221 tattctgctt tcatcacact cggaagcatc gtttgtagac aagtgatttt gaatgcgtaa
    35281 gtaatttttt tcatataatc agctaatgaa agtaattctt cattgaccac cggagcaagg
    35341 tctagcaaac gaataactgc cttcaaagat ggattagctg attcttctga tttttggata
    35401 gccataacaa atccttggac atgacgattg ccattaccaa aagggacttc tactcgcatc
    35461 ccgacttgca aagctgtttc catttcagag ggaaccaaat aagtgaatgg ctgatcggtc
    35521 tgcatagtag gtacgtccac aatgacttca gctgttaatg tcatggttcg tttcctcctt
    35581 tttttgtctt ttcttatcaa gcgacaaaaa gttccttgcc tattttacta gagatcgatg
    35641 gatttgtctt atcttctgcc aaatcctaac aaaaaattaa cagcagataa gaaaaaaaag
    35701 aactgtgtca aaaagttcag acacagcctt ttctaccaga caataagtgg cgaatgtttg
    35761 aaaaggaaac agctgggttt gcttttcttt ttagatgttc gctctatttt tctttattac
    35821 attttttgct cttcacggat acgtgattcc aattcgtgtt gttcacgctc tttttgtgct
    35881 tgacgttcct cttcttccat cttcaaacgt tcacgtttta attcaggatg tggatcattg
    35941 actacatttc ctgcatcgat ttcttctaaa gcttgaccga cgctttttac tgaatcaaaa
    36001 gaatctagag taggctgtgc acttgcatcc aattcatgcg cgcgtttact tgctaaaatc
    36061 actagagaat attttgaatt tacacgatct aatagtgagt caattgaagg ttttaacatc
    36121 ataagactac atctccttta acattttaat atatttaccg attacgcgat ctactcgaaa
    36181 atgttcactg gcaataatgt ttttgattcg ttcaactgct agcggcactt catcatttac
    36241 aacagcatag tcgtaaagag ccatcatttc gatttcttct tttgcaactt tcattcgttt
    36301 ttcgattact tcatctgcat ctgttcctcg gcctacgatc cgtgatttta attccgctaa
    36361 atctggcgga gtcaaaaaga tgaatacacc atcgggcact ttttctttga cttgttttgc
    36421 tccttggact tcaatctcca agaaaacatc ttttccttca tccaatgtct tgttgacata
    36481 tgacaaagga gttccataat aattcccgac atattctgcg tattccagca tctctccagc
    36541 ttcgatcatt gattcaaact cttctttgct tcggaagaaa taatcaacgc cttcgacctc
    36601 cccttcacgc attttacggg tagtcattga gatcgaatac tgaaaatcat tatcctcact
    36661 ctcaaaaatt gcttttcgta ctgtgccttt tcctacaccg gatggaccag acaacacgat
    36721 taataatcca cgctctgaca tgacgacgtc ctttcaacta gtctttttgt acttatcgtt
    36781 tattttgcac tttttttctg caactttcaa ggttatcttt aattatagct agaaattggt
    36841 aaaaaagcta ccctgtacca agaggtcgta aaaaagctgt cctgcatcaa gtaataagaa
    36901 cagccaaaca taaacagctt ctcatgtttt tcgtttggtt ggggttatta tcgcagatgc
    36961 aagcttttga acgccgtgta taagaggtcg tgaagaagcc gattagtttc gagtatgaag
    37021 aaaaattttg tgaaaatagt ttctcacatt tttgcataaa tttggcttaa taccgagaaa
    37081 atggtttttg aacatcactt attcaaaata aaaaaagatt gtgacacgaa ttttgtcaca
    37141 acctttaaat gtattcctag agcaaagaag ctaagcgaag aaatccaatt ctgtttattt
    37201 attgtatttc tttgttcagc atccttgcta aaagcccata ttggacaaag tattcactac
    37261 acccatgatc tcatcttttc gagaacgtgc tttttctgtc ggatcttcta cctcttctgt
    37321 gtcaattcga acaataaatt tccgattcat cgtcacgtaa gcaccgtcgt tgatcaaaat
    37381 aaacagttcg ttctcattat agtctgcaca ggcatctttc catacgtcaa agccgttttt
    37441 ttcagaaggg atatcccgtt taaccacagt ttttccactt aattcgtgga acgttacgtc
    37501 ataatatttc attatctcta cctctttcgt cattcaatat tttgtacttg ttctctgatt
    37561 ttttctaaga tcgtcttaga ctggacgact tgatttttaa tttcgattgc atttgatttg
    37621 gaaccgatcg tgttgatttc ccgattcatt tcttggatca ggaaatctaa ttcccgacct
    37681 acaggacatt gtgcttcgat aagttcatct agtttttgta catggatcgc cagacgatcc
    37741 agttcctcgt gaatatctcc gcgttccaac aagatggcta gctccgtcaa caaccgttgc
    37801 tcatcgactt tcgctccaag aaattcctcc agcttttttt gataccttat ttgaaattcc
    37861 ttttcataga tttctacaaa actatcgagt ttttttagta cttctttgaa ttcttcagta
    37921 ttctttttca acactaaagc taaagcttga ccttcttttt ctcgactcgc ctcaatagaa
    37981 tcaagtgcgc ttttcaatgt atctagagct aactgtgcca attcttccat gctctcttcc
    38041 ggtttttctt ctaccgttac gaagttttcg tccagcacga agcgttccgc catccgacta
    38101 attgacactt gattttgact accgtatcgt tgttgaattc cgtctgtcaa ttgagtgata
    38161 agtgaatcaa tcaattccca gttgatgacg atctgttttt cgtttttgcc aatataagct
    38221 agattcacaa atacttcgat tcgaccgcgg cttaactgct gtttaataag ctgacgaaaa
    38281 tcgttttcaa caaagttcag gattttagga cttcgtattt gaacatctag aaaacgctgg
    38341 ttgacacttt ttatttcaat atctaactga tacgcttttg tttcgcggat ggctttgcca
    38401 aaaccagtca tacttttcat tcgacagggt ccttcctcat tacatatttt ctattgcttt
    38461 ttgcagttgt tcaaactctt cgttcgtcaa tgtcaggcct ttccccattt tttcatggtc
    38521 tggcgcccaa tctcgaagat cgaattttgg cgggcgacca ttccagctga ctaggttcag
    38581 ttctttacgc caccccttgt tgttttctga caatatagcg atttcttcta cgatttcata
    38641 tgaaaattct tgtgccatgg ttgttcctcc ttgagataat ataaatatag gatcagtaat
    38701 gtgtcaactg gttgcttaag caattcatgc tgcaaacgat ccttgcgttt tccttgtagc
    38761 agataatcaa aataaacagt tttcgtgcgc tcattttgta ttttttgctg gtattttcga
    38821 taccttcgcc attcttcagt acttaattga ccaatttgtg ccaataaatc atccggcata
    38881 ctttttatat cttgttggca gatcatttga atcatcatgt ctacttgata gatttcattg
    38941 ggcagtaaaa aatgtttttt tgctaaaagt tctagcatcg ccaatccgca tgtctctggt
    39001 acgaccctgt tcttatataa attacgcagt ttttgccaaa attttatgct tttgaaaaaa
    39061 gataattcta actgaatttc ttttgttaag taagacaaaa atcctcgcca gtatgttctt
    39121 gcaggtttaa cagaatgaaa tgtataccag ttcccatagt aatagcctaa tcgttttttc
    39181 atttccagat agcctaattg taaatttaat tggttccttt ggctatcaaa aagcagaaag
    39241 ctgcctagtg tccacaatgt ttgacatttc caatggataa aaatgtctgg catacgaatt
    39301 tttttcgctg ggcctggccc ttgcacatct acgacaaatg cctctgttgc tcctttgtta
    39361 atcgcaatat caataggtat tttgttgcga tacccaccgt ctgcatattt attttttccg
    39421 atctttcgat aagccatagc gggataaaat gaagcagagg cgagtatcca atctggtatt
    39481 tcttctgttt ttgtctgttg gatatcagtc actacttccg ctagttctgg cagtttagta
    39541 gacaccgtat ataaacgtat tttgggatta tgtttgagta aggacaaatc caaattgtct
    39601 ttgaccatct tttccaatgg agcagaagaa accccgcctt caattagtgc tgttttcgtc
    39661 atttggcgtc tttctcgata gaagcgttca cgaaggtctt caactgcagc catttctggt
    39721 aacgcaagca cttgtcttgt cgacagcttt ttccataaat tcacagcttt tttcatatct
    39781 ccttgtaaaa tcaatgcgcc gttcaacgca cctaccgagg tacctgtgat aatctcaaag
    39841 ttgatatcat gttccttcag cgcctgccac acaccaatct gataagcacc gtgcgctcct
    39901 cctccaccta aaacaagtgc tgtatgatag accagctttt tatttaattg tgtggttcct
    39961 tgatagccgt ttttatgaaa aatacgcaac cattcttctg atagaggaga ttgaaataaa
    40021 aaacaacagt tttctttaat aaaaaaacga gcgcaagctt ccatataccg aaaaaatttt
    40081 ttccattcaa aagtttcacc ttcaatcaac agattattaa aaataacatc tcctctactt
    40141 ttagcaatag taaaatagac ggtatatttt ttcgatactg ctttaaaagc acattgcttt
    40201 tttgcagaac gccaaaaagc gtctctactt tcttgatgac tttgaaaaaa tggaaggggt
    40261 tgttttgctt gctggatagg cgaatacagc gacattttct gtgaaaagta aacttttttt
    40321 atctccatcg cgctctcctt tttcttcaag tataccagta cgtcataaaa aggtcatgag
    40381 tctcgtattc gactttgtag attccataag aaaacaattc ataaaacctc ctttaaataa
    40441 aaaaatacaa aaatcacaaa aattaattga aaatgagagt gttttcaatg aaaacgtgat
    40501 tttgtaatgg aattttaaaa taaaagaaac aagctttttt aatgcaaatg ttgtaaaata
    40561 aaagagatta agaggaaata agaggaggaa catgatgact gagtcagttt atgtacatat
    40621 tgataccaca agtaatgctg ttttaacaaa agggctgact gctactgact ttgcaaacag
    40681 tatcgtgcat tttcctcaaa acttgctctt gcttgatcca tctgcttctg ctggagaata
    40741 tgaatcccat acagggctga aagtaatccg tggtacagaa aatattcagc gtttcttttc
    40801 ctcttctcgt aacaggcgtg gattcgatga attgaagtgg atcgacttta ctgatttaac
    40861 gatgctgaaa gaattgacac ctttagaaat ttcagaatta ttatattttg gtcatatgaa
    40921 aacacatctt cattcgccgt ttttttataa actacagaat aattttgtat acttcgatct
    40981 taatgatcag ctgaatcgga tttattatcg ctatttagat gaattttata ggatttttgc
    41041 tagtaaatta agttcgatct tgtcagataa gatcaatgta aaaaaatctt ttttcaaaaa
    41101 agaaacacct gttgaaaaaa tcagtgtgga attattgaaa gaaatgcgta atttgatgca
    41161 ggaagggatc attttttctt ttgatcaagt tggtttgatc gatggtaaat atcgtatccc
    41221 aatctatgtg attgaagatt atatttggaa attaaaaggc acccggtatc gagaagagga
    41281 aatcatcgct actttaatct actctgtcac cgatcgacac tggcaattgg tagaagatgc
    41341 cgatctttct tatctgccat tgaagtagat ctatttctta tcaaaaaata aaaaggaaac
    41401 aagaaactag gacatgattc tgtctcaagt ttcttgcttc ttttttattt acagctcctg
    41461 tcgtttatct ggcacaaaaa tcgaaggagt cgtttgttgg atccctaata aaacgatgat
    41521 cgttacaata gctgtactca acccgctggc accattcatt acgaaagaaa agagccaagg
    41581 attcatcccc catagtgcat acgctcccca gaaaaccact cctgcaataa aatgccaaaa
    41641 atatctggaa agtgcgccaa tcaatgcacc aaacacgatg ctttttctaa tttgtttcgt
    41701 attatcgtct acatagcctt tttggacatt tgaagccatg agccctgctg cgcctgcaaa
    41761 agtataggca atcgggtact caatcaacac ttgaacgaca cttaaataat aaacttgtcc
    41821 caacggaaaa tgtaggatgc cccaaatgaa acctgccagc atccctgcct ttgtccctct
    41881 tcttaacgca aaaagagtca atggaatctg ccctaatgaa atagaaaaac tgctgccgat
    41941 ctggatcgga atcaacgaca acaccatcgc taacgctgca acaatcgttc cttctaccca
    42001 aactctattt tttcccataa aaaaacttcc tcctttgaat aaaaaagtca caaaggagga
    42061 agcagctttc gaaaatagtc aaacagctgt ttattcacaa ttcctacgct cgcataaccg
    42121 atacaggtac gaagggttta gaaatagatt caatctcagc ccaattggac tcccctttat
    42181 gagtttattt attatttatt ttttgtttca aacaatggac taactggttt gttttcatgg
    42241 atacgtttga ttgcatctcc cattagtccg ccaacactta cttcatcgat tttgtcgatt
    42301 ttacgatctt ctggaagata gatcgagtct gtaacaacta gacgctcgat agctgaatct
    42361 tctattcttt gtaaagcagg gccggataat actggatgtg tacatgaagc atacacacta
    42421 gttgcaccag cttctttcaa agcattggca gccaatgtga tcgtacctgc tgtatcgatc
    42481 atatcatcga tcagtacaca agttttgcct ttgacttgtc caatgatatt cattacttct
    42541 gcaacatttg cttttggacg gcgtttgtct atgatcgcaa tcggagattt caaaaattcc
    42601 gctaatttac gtgcccgtgt gacaccacca tggtctggtg aaacaacgac aacatcatcg
    42661 cctttgattc ctttttctaa gaaataattg gcaataagtg gcgcacccat caaatgatcg
    42721 actggaatat caaagaaacc ttggatttgg actgcatgaa ggtccaaagt cagcattctt
    42781 gttgcaccag ctttttgaat catgtttgct actaatttcg ctgtgattgg ttcccgtgca
    42841 cgtgctttac ggtcttgacg cgcatagcca taataaggca tgactacgtt gattgttttt
    42901 gcacttgctc gtttcagtgc gtcaatcatg atcagcaact ccatcaagtt atcattgact
    42961 gggctgctcg ttgattgaat aacatagaca tgcgatccac gaatactttc ttcaatgttt
    43021 acttgaattt ctccatcact aaattgagta acagatgatt ttcctaactc gacgccgact
    43081 gctgctgcaa ttttctctgc taatgggcga ttggaattta acgcaaaaat ttttaatctt
    43141 gggtcaaagt aatgttttga catggggacc tccactttct ttttcacaac tctagaattc
    43201 tacctaataa atagtagtca tattttttaa ataaatcaag tgattttgca aaagtcttag
    43261 tttagataag ggagtttttt tgcatatcct tctttattga cttgtcttgc tctcgcaatt
    43321 gccagcgcat attctggaat attgtctgta attgttgacc cggcagcaat cgaactgttt
    43381 ttagctacct cgacaggtcc gatgatattc gtgctagaac caataaagct gtggtcgccg
    43441 acagtcgtat gatgtttgtt ctttccatca tagttgacga agacaacacc acatccgaca
    43501 ttgatttctt ctcccagcgt agcatcacca acataagtca agtgaccgac tttagttcct
    43561 ttgccgattt gagcattttt cacttccaca aagtttccga tatggacgtt ttcgccaatt
    43621 tcagcttttg gtcgtaaatg tgcataaggt cccacatctg catgtttctt gacatggctg
    43681 ctttcaatga ctgagttttc aatgacgacg tgatcctcaa tcctactgtc tacgattttt
    43741 gaatgtgacc cgatgacaca atcagaacca atgactgtat ttccttggat ttgtacacct
    43801 gcttcgatca atgtgtctgg accgatttct acgcctgcat cgatgtatgt cgttgctgaa
    43861 tcgacaaagc ttacgccatt gaccatatgc atctggttaa ttcgctttct catgatctca
    43921 tttgctttag ctaacgcgat ccgatcattg actcccattg attcttcaaa atcatccgtt
    43981 tgataagcag caactgtatg gccttcttct tttaagattt cgatgatatc tgttagatag
    44041 tattcacctt gagcattgtt tgttccaact ttgcttaacg catcgaacaa agcttcgttg
    44101 tcaaaacagt aagttcctgt attgatttct tgtacaagag cttcttctgg tgttgcatct
    44161 ttttgttcca cgattttttc tacgatccca atatggtcac ggatgattcg tccatatcct
    44221 gttgggtttt ctgcttgtgc cgtcaagatc gttgcacttg cattttttcc ttggtgatat
    44281 tcaaaaagat tgttcagcgt ttcagtagtc aataatggtg tatcgccact gataactaac
    44341 gttgttcctt tttttccttc caagaaagaa gcagcttgca aaacagcatg tcctgttccc
    44401 aattgttctg cttgtaacgc atatttactg cgttctccta gttgtgcttt aacttgttct
    44461 gctccgtgtc caacgatcgt aatcacttca tctggtttcg tttcactgac ccgattaatg
    44521 atatgttcta ccataggttt accagaaacg ggatgtaaaa ctttatataa ttttgacttc
    44581 atgcgggtac ctttccctgc cgccaaaata attgcataac gtgcgtccaa ctgcgtcact
    44641 cctaaatata gtttgctgat ttcagtttat cccagtatac ccattttttc aacaaaacaa
    44701 gtgattttct tttatcccag cgttttctgg ataaaaaaat agatagacca taacgggcct
    44761 atctatttgg taaccggtgc tctcctgcca actcctcggt cacaagtcac actactcata
    44821 aaacatgaaa agctgttttt tgaaatcgtt tcttgtgact tagagttaaa cggtaggctt
    44881 acaacctctt cattaaacgt ttttcaatca gctgaccttc ggtattagct caataaacgg
    44941 caaaatatga ggagcaattt ttccgtttat tgagctaata ctcaggacag gacgctgatt
    45001 tcacaacctc tagataaacg gtgttcaaaa gccagtttct cggtattaag ccaaatttat
    45061 gaaaaaatgt ggaaagccat tttcacaaaa tttttcttac tactcgaaac taagcggctt
    45121 tttcacaacc tcttattctg aaaaataatt tcctggcaca accgtaatat ttttcgtttg
    45181 agtatctaca tctttgacat aaagcagtga cgtataatca tcgatggcgc gatgaccgtt
    45241 gaattttgat tcggcaaata cagtgatgcc aacaagttct gattcgaatt cttcaatcaa
    45301 gctcttcatt ccgttgactg ttccgccgcc tttcatgaaa tcatccacta caaggacacg
    45361 tgaaccacgt ttcaaacttc tcttagacag ttccatcttt tcaattcttt cagaagatcc
    45421 agacacatag ttgacactta ctgttgatcc ttctgttatt tttgagtccc ggcgtacaat
    45481 aacgaatggc gcattcagat aataggacac agcttgggca ataggtacgc cttttgtggc
    45541 tacagtcatt acagcatcga ttttttcacc aaggtattta gaagcaatga ttcttccaac
    45601 ttgacgcagc agttcaggtt ctcctaacaa atcagagaga taaacatatc ctcctggaag
    45661 cagacggtct tgttctgata gacgttctgc tagagattca atatattttt tcgcctcttc
    45721 atatgaaatt tcagggatga acaatacacc acctgcagca cccgggattg tttccaaggt
    45781 tccataccct cgttctttaa atgttttctt gatgattccc aaatcttcac tgatagaaga
    45841 tttagcagat tcataacgtt cggcaaagct tgttaaggaa atcaattcat gcgggtgatt
    45901 caataaatac tgtgtcatgt caactagacg ttcactgcga cgtactttca cctattccaa
    45961 ctccttttaa gaaattttat cgttttacat tatataagtt tttcttcaaa aattcgagca
    46021 ttttatgaaa aaataagaaa atagttcggt atttattaaa ataaaaagaa gcctataaaa
    46081 aatttttcgt ttttataagg cttcttttct ttataattta gttatttttt cttctgaagg
    46141 caaccaatat tcgtttgatg atatttacaa tcaggaacaa agcaataaag actaatgtga
    46201 ttgttgctcc tggaggtgta tctagataaa acgagctagt tagtcctgac agcatcccta
    46261 gaaatcctac acaaacactg atagcaatca cgacattgaa gcttttgcct aatcgcatac
    46321 cgattgctgc gggaagaacc atgattgcgg atatcaaaag tgcaccggca atcgggatca
    46381 tcacagcaat agccacacca gtaatcacat tgaacatcat cgacatcaaa tgaacgggta
    46441 gcccatccac gtgggcggta tcttcatcaa aagtcagaac atacatcggc cgtttgaata
    46501 aaaagaacaa tataccgatg gcaacgaata agattcctaa aaagatgact tgctcccatg
    46561 taatggtcac gatcgaacca aacagatagg attggatact tgttgctgaa ttccctccgc
    46621 tcaaattcat caatactaac gctagcgcca aaccaccagc cattaaaatg gcaatggaga
    46681 tttctgaata ggttcggtag atcgttcgca gatactccaa tatcacagct gctaatacaa
    46741 cgactagcat ggtcgtaagt gtaggattaa ggttcaaaaa gaatcctaac gctacccctg
    46801 ctaaagagac atgagaaagc gtatcagcca tcagcgattg tcttctgatc actaaaaaca
    46861 cacctagcat cggggcgatt ccggcaatga agatagcggc aagaaacgct cttctcatga
    46921 attcatatga aagcaacgcc attgagaatc ctcctttctc accagtcgga tctgtctgtc
    46981 cgcatactgt ttgatatctt catgatcatg ggtgatcatt agaactgatt tcccatggac
    47041 atgcgcacta tgtcggagaa gacgataaaa ttcatttctg gattcttcat ccatacctgt
    47101 tgttggttca tcaagaacaa ataagtcagg gtcagtagca aaaatacgcg ctaaactgat
    47161 tcgctgcttt tgtccgccag acaattcacc tattcgccga tttcgcatat cccacatccc
    47221 tacagcttct aaagcacgct gtacatgttg atgatctttt tcagagagac gcttgaacca
    47281 gcggcctctt ggatatcttc ctgaacggac taattcgatc accgtactag gaaaacctgc
    47341 attgaaagat gcaacttgtt gaggaatata accgatactt aatttttttc cttcttgatt
    47401 tttctcagca atctttatca ttccttttga aggtttcagt aatcctaacg atgctttcac
    47461 caaggttgac ttggctgctc cattttctcc agttaaaatg acaaattcac ccgcatctac
    47521 atgataagag acatcttcta gtacaggttc atcatcatag taaaaggtca aatcagatat
    47581 ttcgatataa cgcaccttac aacctccatt ctaaaactta attgatactt tcttttaaag
    47641 ctttcagatt tttttccatg acagaaatat aattttcgcc tgctttgatt tgttcattag
    47701 tcaagctttc taaaggattc aacacttcta gcttcactcc tgtttcattc gacaatgtct
    47761 cagctacctt cgaagaggca ttttcttcaa aataaatcac tttgatgttg tttttcttca
    47821 caaattcttt tagctcagct aagcgacttg gtgtgggttc ctgatctggt gaaacgcccg
    47881 aaatcgctac ttgttttaag tcgtattgat tcgctaaata agcaaaagca gcatgctgag
    47941 tgacaaatgt gcggtttgtt gcatctttta gctcatcgga gtatttttga tccagtgctt
    48001 caagcttttt gatataagca tcggcattct tcgtaaaagt ttccttttta tctggatatt
    48061 tttcgcctaa ttcttcagca atcgttctga cttcttttat agctaatacc ggatcgagcc
    48121 aaacatgtgg atcgtattca tgtgaatgac catgcccttc ttctgattct tcatgttcgt
    48181 ctgcttcttg cgattctaaa cggtcgattc ctttagctgc ttcgatcatc aaggtctgtt
    48241 tgctatccac tgaatccttt aacgaatcca caaaaaattc catgtctgaa ctattataca
    48301 cgaaaacatc tgcatcggaa atttctgctc tttcttttgc acttggttcg aaatcatgcg
    48361 gctccgttcc agcagggatc aaaagtttca cgtttccttc atcccctacg atctcttttg
    48421 taaaatcata catcggataa aaagtcgtaa cgatcgtcaa atcctctttt ttgtctgctt
    48481 ccttgttcgt atttccacat gctgcaaaca gtaaagcacc tatcattacc gtagctgtca
    48541 aaagatattt tttcatttat atgctccttt caatgaacaa atcggaattt tacgatttat
    48601 taacgtgaac taatgtatca aaataaaaaa acacagtcaa tagaaatcca tcaatttctg
    48661 atttaagcat gtatattctt gattaaatcg taaaatggat gagttgctgc tcatatctag
    48721 ccatttcact acaataaaaa actgaagaat accattttag gattcctcag tttttcatca
    48781 cctattttac ttcttatatt ttattgcagg gttcgtacta aataaacttc ctcacaaaaa
    48841 ccttttaacc cattatatac tctctgcgct cttgaataat gttgacacaa ggcaaaaacg
    48901 gttggtccgc ttccactcat caatgcagca tctgctccgt acttgatcat acgctctttg
    48961 atttgatgga tgactggatg ccgctttccc gttatatctt ctaaactgtt tcccattttt
    49021 ttgatcatct gctgataatc ttgctctcgg atggcttcag caagtccgtg gatgtcttga
    49081 tgttggatgg cttgcgtatc tacttctcta aacactgtac gtgtagagac actcattctt
    49141 ggtttgacca acacaaccca gcactgtggc atagaaggta atacttggat ttcttcccct
    49201 ttgccaccga caaatgccgt acttccgtag acacagtaag gaacatctgt accgacttcc
    49261 aaaccgattt ctgccagttc ttctaacgaa cagcccagat tccataattg gttgatccct
    49321 cttagagcag ctgcacagtc tgtacttcct ccgcctaatc cagctgctac tggaatattc
    49381 ttcttaacaa agatcttgac accggttttg atattgtatt tattttttag caataaagca
    49441 gcttgataaa cattgttccg ttcatctacc ggtaaaaatg ctttatttgt ttctacaatg
    49501 attttgtctt ctgttatttc ttcaaaaaat agatgatctg ccaagtctac gctcgacatc
    49561 accatttcca actcatgata cccatcttgc cgtctatata atacatccag tcctaaattt
    49621 atcttggctg gcgctttttc aatcaattcc atcctctcac ccattcgaaa agtctaagtc
    49681 gcaagtattc tatcataggg aaaaataaaa gtatagctta tgtctgccta gtggttgatt
    49741 ttgtcatcgt ttcaacagct ttcacagaat tttctcttca taatccaaac aagttctagt
    49801 gattcttata attctgtgag cacttcttct gccaaactcg gaacatttcc tttttctttt
    49861 cctatcagac tgagtagctg catggtagca aatccgaaat tacttccttt cctataagca
    49921 aaataacgtc cttcccaatg atcgacatat tttaatttct tttcataagc agactggaag
    49981 gaatagaaaa aattaccata attatatacg atatgcatga ctttttcttg aaagaaagaa
    50041 aaatctgttt ctccaacatt agctaatgga gctaagccta gattggcttc cgagtagccc
    50101 attttctcgt atacaataaa cagattggct aacagatagt cagctaattc ctcagattct
    50161 ttaggtaaga cccgcaacaa atcatatccc gcctgcttct tcgtcatcgg ctgagcggtg
    50221 atgaagccaa cgactttttg atctttacgg acaataccga caccgctaga taatacatat
    50281 gatttatcaa atcgtcccac agagaagtat ttttctcgtg caccttgaag ccatttttgt
    50341 gaaacttcat ttacagcttg atgtaattct tccggcagtt gatcgtacca agtaaaatgg
    50401 tatccttctt tcatcaaacg ttgatattca agttgctgac tcagccgaga caagtcttct
    50461 gttgctagat caacaatccc tgcttcacct actttcgtga agtgaaaacc caattcatga
    50521 agcatcacta cgtagctttc tgatatctta taaaacgcaa gctgatagcc taaacaatct
    50581 gcttgtttca taaactgatt cgttgctgcc cgcatcattt taggattgcc aactggatct
    50641 cctaaaacaa agcatttgtt tcctttgatc tgataaccaa aaacgacttg atcttggtcg
    50701 tcttcttggt aataaaaata actgtaacct gacaagcgaa gctgatggct tgtagctgtg
    50761 cctccgtatg tttccaataa acggtcaaaa cggtcttttt cgtactcact gccaagcttc
    50821 gtagtatctt cagctaaata ttgataaagc gccactaaag ctagcaatga gatgcccaaa
    50881 ccaataagcc ctgagaacca cacatcatct gaaggaaaca aaataaaatg atttcctgtt
    50941 attcgaccga ctaaaaagcg tccgctgtga tagcctgcaa ttgcgtaaac gataaacaaa
    51001 aagccgaaca agctagcatc aaagattata gctccccaag aataaacgaa ttttgttcga
    51061 taaaattctt ttctggataa ccacacagct aacagaatca agacatatac caatatcaac
    51121 tgccaagata acgtacgtgt gattgtattt aaaataccaa aagatagtaa agcaatcgta
    51181 ggcagaaatg cctttttgac ttttactgaa agtgctctag caaggccgag taataaaaag
    51241 ccaaccaata gattcactgt ctgatctaaa aaattgaatg agaacggcaa taatacttga
    51301 aatagccgac tgattgcaga cagattagtg attgttgata gaagtaccat catgatcccc
    51361 gcaaaataga cagcacttac gagcacgata tgcgcaacct tttggaaaaa cagtcgcgga
    51421 atgttatcta aaaatcgatt gattttgact cctgtatgtg tgatgaacaa tagaagtccc
    51481 gtcataaaag gtagaacata ataaaacaac cgataatata atagccaaac tactgctaca
    51541 tcttgccgaa cagacaattg actcattcct aagatcatca aaacgtcaaa agtccccatt
    51601 ccacctggga ccatcgtcag cattcctatc aatgtagcaa tcatgaacat aggatagatc
    51661 gaaagcatcg aaatatctat tctcatcaac ttgccgatga tcaaaaatac cgcaagggct
    51721 cccgtccatt gtccaaagga tgccagtagc agaccaagca agccttttgg ataaaactcg
    51781 aagaacaatg tctttctctt tagataagca aaaaagaaaa tgactggtgc taaaaaacta
    51841 ccgccgaaaa gccagatcca atagcttcga aaaatacttt ctgactgaat aaaaaagaca
    51901 tcaataaatg taagaaacga ccatacagac aaaccagtca gcataaatag tgcgactttt
    51961 gatacagtgg ctaaaaccat ttttctattt gtctgctttc cataaaaact agcccgcaga
    52021 cttgctccta ccacaccacc aaaaccggcg agattgttga tcgtgtttgt tacccacgca
    52081 gcaagaagaa actcttttct ttccattttt ggttttcctt gtttttctaa gactctgatc
    52141 gtcacccaat catacaacaa catcggagtg acacccagca gtccagccag aatcatgagc
    52201 aggatcgtca tgcggctttg ttgtcccatc ctttgccaaa tatcttgcca actcatgcca
    52261 ttagcaatat ttgcgacttg atttgccaca aagactaaca cggagccgaa aaaaatcagt
    52321 tttaaaatca gactatgttc ctttatccat tgcagcatca agtatcgttt atttttcaca
    52381 ttttcccatt cctaacttgt atacttttgt gtcatacccc aatgttatct tatttatttt
    52441 aatttttcca ctttagacct gttctttgct tgcgatgata gaaaaagaaa gatatcctaa
    52501 tgctaaagga gaggataaca tgaaagtagg atttatcggc acagggaata tggcacaagc
    52561 tattattgat ggtttattaa aaaaaggaac agtctcgaaa gaagaggtgt tcgtttccag
    52621 tggacatttt gaaaatgcac aaaaatttgc tgctgaaact ggcgtccatg catgcaaaag
    52681 taatcaggaa gttgcatcac aatcagatat cgttctttta gccgtgaaac caaaaatcat
    52741 tgaaaaagta ttggaagaac taagagaata tagccagaaa gtcttattca tttctattgc
    52801 ttcaggaaaa tcattaatag atttagaaac agcgcttgaa gatcctcagg cctccatcgt
    52861 acgtgtgatg ccgaatgtca atgtcagcgt aggagcaggc gtttctgcga tttgcaaaaa
    52921 tgaagctgcc acggaggaac agcttcagca agctacgatg atttttgaag caatcggcag
    52981 cgtctatcct ttagcagaat cagatttcag tacattcatt ggccttgctg gcagctcacc
    53041 cgcattcgtt tacatgctga tcgatgcgat gggacggact ggtgtactga atggtttgtc
    53101 caaacagaca gccactgaga ttgctgcaaa agcaattatg ggttcttgtc aaaaattcct
    53161 ttcaagtgat aaaaatccat gggaacttgt agaccaagtt tcttctcctg gcggtacaac
    53221 tgttgcaggt gtagttgcct tagaagaagc aggattcatc ccagcaatca tcaaaggaat
    53281 caatacgacg atcgagaaag atcttgagat gttgaataaa aaataatgat agcaatgttt
    53341 tttcgtgcct tacaaaaaaa gaagagctgt ggcttttgcc gcggctcttc ttttgtattt
    53401 tttattattt agcataatca gttgcacgag tttcccgaat aacgattact ttgatgtgtc
    53461 caggataatc cagttcttct tcgattcgtt tacgaatatc acgtactaaa cgaacagcgt
    53521 ctaaatccga gatttcttct ggcttgacca ttacccgaac ttcgcgtcca gcttgaactg
    53581 cgtaacttga ttctacaccg gcgaagctgt tcgaaatatt ttccagactt cttaaacgac
    53641 ggatgtagtt ttctaatgat tcacttcgcg caccaggtct tgctgctgag agcgcatctg
    53701 ctgcagctac aaggacagag ataacagaag tagcttccac atctccatga tgagaagcga
    53761 tcgcgttgat tactactggg ttttctttgt acttggcagc taattccgca ccgatctcaa
    53821 cgtgagatcc ttcaatctca tggtcaagtg ctttcccaat atcatggagc aacccggcac
    53881 gttttgctaa ttggatatct tcgccaagct ctgctgctaa gataccagct aattttgcaa
    53941 cctcgaccga atgcttcaag acgttttgtc cataactagt tctgaatcgc agacgtccga
    54001 tgatcttgat tagatctgga tgaagtgtat gagcaccgac ttcaaacgct gcctcttccc
    54061 cgtattcgcg aatacgttca tccatttctt tacgagattt ctcgaccatt tcttcgatac
    54121 gcgctggatg gattcgtcca tcttgtatca gtttttccaa ggtcatccgt gcgatttctc
    54181 ttcggattgg atcgaatccg gaaagaacaa ctgcttccgg tgtatcatcg atgattaaat
    54241 cgataccagt cagcgtctca agcgttcgaa tattacgacc ttctcgtcca atgatacgac
    54301 ctttcatttc atcattcgga agggtaacga ctgaaacagt cgtttctgaa acttgatctg
    54361 ctgcgcagcg ttgaatcgct aatgataata agtttttcgc tttgcgatct gcttcttctt
    54421 tggcacgctg ttcagattct tttaccatta gagttaactc atgattcagc tcttcttcag
    54481 tcgatttcat gatgacatct cgtgcgtcct cttttgataa accagcaatt ttttctagtt
    54541 ctttttgttg atcttcaatc attttttcaa cgtctttttc tcgctcttca attaattgct
    54601 gttttgaact aagtgcttct tctttacttt caagtgagtt ctcgcgtttt tctaacgagt
    54661 catctttacg attcagcgtt tgttcgcgtt gaatcaaacg attctcttga gattttaatt
    54721 ctaacttact ttctctcagc tcactttcaa cttcagaacg gtatttctga ttttcttcct
    54781 tagcttctaa caatgcttct ttttttagag tttctgcttc tttttttgca ctatcgatga
    54841 ttccagcagc tgatgattgt gcaccagcta tttctttctc gtgacgtgac tttgcgacca
    54901 taaaccctaa accaagaccg acaattaaac cgatgatagc gaggagaatg ttgaatacca
    54961 taaaatccac ctccatacta tctttttcat ttttatcatc tatacagctt ctatgataaa
    55021 ttattctaaa ctcgtcaata tgcatcttcg catatatgtg tacaaaaaac atgcacaact
    55081 ttattctaat gtttgtaccc cgtagtgtca actttaaata aacaaagaaa cggctttcta
    55141 cttattcatt aaacgatggt ttttaaaata aatgacacta gtttcatata ggtaaacctt
    55201 taaattgaga aacttttcta ttaaattatt ctttgtagat gaacagatat ttttatttta
    55261 tgtacccact cgtataatta aataactcac gatttcttta ttcaataaaa aaacggcagg
    55321 tcaaggagag tacctactct tcagaccagc cgtttttgtt tatcataatt tttattcttc
    55381 tactaaaggc aattcttctt gtcctttttc atcttctggg acagcgactt cttcaccaat
    55441 accataagct gctctaacta gagcagaaac ttctgccatc atttcaggat gattagccat
    55501 atagatttta gcgttttccc gtccttgacc aatccgatct tctttataag aataccaagc
    55561 accgctttta tcaacaatgt ctttttctac tgccatgtct agaagttctc cttcttgtga
    55621 gatccctaaa ccatacatga catctacttc agcgattttg aaaggaggtg ctactttgtt
    55681 ttttacgact ttgatctttg tacggttacc aacaatatct gtaccttgtt tcaattgttc
    55741 tgcacgacgt acttccaaac ggatcgttgc gtagaatttc aatgcgcgtc ctccaggagt
    55801 gatttctgga ttcccaaaca tcacgcctac tttttcacgg atttggttga tgaaaatagc
    55861 gattgttttt gttttgttga tcgaaccaga gagtttacgc aatgcttgag acatcaaacg
    55921 tgcttgtaac ccgacatgtg agtcacccat ttcgccgtcg atttctgctc gtggaactaa
    55981 agcagcaact gaatcgacta ctacgatatc tacagcccca cttgatacta aagcatcagc
    56041 gatctctaga ccttgttctc ctgtgtcagg ctgtgaaaga agtagttcat cgatattcac
    56101 acctaatttt tgtgcatatt gcggatctaa cgcatgctca gcatcaatga aagcggccgt
    56161 tccgccattt ttttgtactt ctgcaatagc gtgtagtgca actgttgttt tacctgaact
    56221 ttcaggtcca tatacttcga tgatacgtcc acgggggtaa ccgccgacac ctaaagcgac
    56281 atctaacgca agagagccac ttggaattgt agagatttgt tggtcgattt tttcgcccaa
    56341 tttcataata gagcctttac catagctctt ttcaattttt ttcagtgcag catctaaggc
    56401 tgctttacga tcatctgcca atacgataat cctccttata tttacaaatc agagcaacat
    56461 ttcattatcc ttatcatatc ttttttagtg aaaaaaagca agaaaaaacc gaacaaatat
    56521 tcgcatttat cattttctta aaagctgttt tctcaaaaga tcaaatcctt gcataaccgc
    56581 attatatctg atagcagcac gatctctggc aaagtgatat ttttccgaaa ccacgccgtc
    56641 tttagatgaa atagcgatcc atactgttcc tgcagattga ccttctaacg tgtccggtcc
    56701 agccactccg gtgaaagcta cactgtaatc tgttcttgct atctcacgtg cttgaatggc
    56761 catctgctcc acacattctt tgctgactgt tccatattct gctaatagct ccggatcaat
    56821 ctccagaaaa ccagcttttg tttggagcga gtaggtaacg aatccgcctg gaaatacttc
    56881 agatacacca gcaatgtcgc ctaatgcggc ttggaaggcg ccggctgtca aactttccgc
    56941 tgctgttaca gtctgcttgt tttctttcag tagttccact acgacttttg ctagcgaatt
    57001 atcatcgccg tatccataaa aatattcccc tactcgttct tggatttttt cttctaatgc
    57061 taaaagagct tgattccctg cctgaacatc atttgttttc actgtcagtc gtaatgtcac
    57121 ttcatttggt ttggcatatg gtgcgatcgt tggattgatc tgtgtctcaa tcagatcttt
    57181 tagctcagtg accagtcgcg attcaccaat cccataaaag cgcaaaactt tagaaattag
    57241 tttttcttca gaaggaaaac gttcctctag taaaggacgt acttgttcca caaacattgg
    57301 tttcaactca ttaggcggac cgggaagaag gatatacgca tgtgtatctg tttgataaaa
    57361 agtccctaaa gcaagccctg tacgatttgg tagaggaacc ccgccttcga taatctggga
    57421 ctgttgcaga ttgtttttgg tcatttttcg atgggttgtt tcaaaatatg ccaataattt
    57481 tttgtatcct tccgtatttt gtatgagaga cttaccgagg tgagccgcag ttgcttcttt
    57541 tgtcaggtca tcttctgtcg gtcctaatcc gccacataag agtatgagtt cacttcttgt
    57601 ttcagctaga gcaatcaact cttctaaacg ctgctgatta tctcctacaa ctgtttgata
    57661 ataaacttcg atacctagat cagctagctg ttctgacaag aaagtggcat tcgtattcac
    57721 gacttgtcct agtaaaagtt ctgttccgac agctattatt tctgctttca ttacttcccg
    57781 ctcccttata tagtatacgc tgtattttta tattttttta tttaaaaaga gggcaaggag
    57841 ctgtgacaaa aatcttgtca cagctccttg ttccaaataa acagtgttct cctgccaaaa
    57901 cctcggtcat aagtcacaat atacataaaa catgaaaagc tgttttttga aattatccct
    57961 tgtgactcag agttagacgg caggctcaca acctctccac taaacgatac ttacattgat
    58021 cctttgaaca caccgctgtt tttgatgaag taatccacac ctgaatagat agtaaagatc
    58081 agacaagcat aaagcatgat ttgatctact ggaataccga tcaggctgaa tgggatatta
    58141 ttgataaaca gcaagataat agcaaccatt tgtgtagccg tcttgacttt tcccggccaa
    58201 gctgcagcca tgacttctcc atgttcgaca agtagtaaac gcaagcctgt gacggctaat
    58261 tcacgacaga caatgatcgc tactacccaa ccaggggcct ttccttggtc aaccaacatg
    58321 ataaaagcag tcataactag cattttatct gccaacgggt ccgcaaactt gccaaaatta
    58381 gtgacaaggc ctcgcgcacg ggcaattttt ccatctaacc agtctgtgat actagctaaa
    58441 gcaaaaataa ctgcacctac tagctgtgtg acagccagtg tggtgtctcc tacgttaaat
    58501 tgtccccaat ctaaaggtaa acctacaacc aaaatgaaaa tcgggatcat acaaattcta
    58561 agtacagtta atttatttgg taaattcaca ctatcgactc ctttcttccc tattctacgt
    58621 gactatcagc gaagtttcca ccgatattat ttacttttcc aaatgaattt attcaaagga
    58681 gtatttttat tgaaattgat ctttttgaat taacgaagaa ggaccgcgac acagatttgt
    58741 cacgatcctt cttttttata cctacaagta aacagatgcg taaactaatt tatacgatca
    58801 ttctgcgtat tgaagagtaa ggttcacatt ttttggactc tgattgtttt cccctggatt
    58861 aactggtacg gattctccat tcgctttgat cgttgcattg cttgctgcac caatcgtgat
    58921 ggtcgcattt gttgctgttt ccggtaacac ggtactctgt gtttcatttg ctgccagtgt
    58981 cccttgataa acataggcat tgtctactag cacacctaac catacacgat tgacagcagt
    59041 aaattcaagg gttacaggct tggtagcgtc tgtgatattt actgcgatgg cactgccaga
    59101 atcttctcct gtagctattg ccattttctt ttcttcactt gattttgttg ttgattctac
    59161 tgtagaagac tctttggtct gcgtgctttg ctctgaggaa gaggactcct cgactgatcc
    59221 ttctacttta agcgaagaag ctgtgtctcc gattattgga tcagcttgac gatcttgcca
    59281 agtcatatag cccacgacaa cgacaatcgc caaagcaacc aatcctaata aaatgacagg
    59341 aagacttgtc caaaagcgac ttggatgcga ttcttcctga tgcattgctt ttctagaagt
    59401 acttactgtt tcaggctgcg gacgttcagg gaccgatcct gtcaatttgc ttttcccatc
    59461 aaaaacatcg actaaatggt ctccatcttc tcctacagct tcagcgtatt gccgaataaa
    59521 tgcccgcacg taaaatttac caggcaattg gtcaaaatca tcattgtcga ttgcttccaa
    59581 ataacgtttt tgaatttttg taatctgctg taattcatct aaagatattt ttttattcag
    59641 gcgtgcttgc cgtaattttt ctccgatggt ttcaaaagcc actcgttcat cttctccagt
    59701 ctgtttgatt ctccgaagca tctgctgttg caacgaaaga cgttatgttt gggtgctgtg
    59761 acaaaagtca tgtcacagct ccttttttcc gaataaacat tgttctcctg ccaactcctc
    59821 ggtcacaagt cacaatatcc aataaatata agaagctgtt ttttgaactt gttccttgtg
    59881 actcggagtt aaacggcagg ctcacgacct ctttcttaaa cggtgttcaa tcagctgttc
    59941 ctcggtatta gctcaaaaac cggcaaaata taaggagata tttttccgta tgtttctcta
    60001 atactcaggt caaaacgctg atttcacaac ctcttcctta aacggtgttc aaaagcttgc
    60061 atctgcggta ataagtccaa ccaagttaaa aacattaaga agctgttttt acttggctgt
    60121 tcttattact tgatgcaggg cagctttttc acaacctctt ggtacacggt gttccagaag
    60181 tagcttcttc ggcaataagc cgaaatatca caaaaatttg agaagcaatt ttcgtaaatt
    60241 ccttcttatt tcttgaagct gaccacttct gtcacaacct ctttgattac ttcgtttgat
    60301 tttattttaa tataagttga ttaaaagaga gcatgatttg ttttattttc tcactaattt
    60361 ttccaacaca actaagaata ccataaaagc tgattttgga ggaggttcct actacaagtc
    60421 taaaacgaaa tttaagactt ttcctcataa aatactggtt tattttggtc tcatgtaaaa
    60481 ctcgctgaag gcctcttcac ttataaatgc ttccccagct gccagtacgt ctttcatttg
    60541 gatcgaatcg atgatttcag gaagatcaaa taaagttcga tcgccaaata aactttgcgt
    60601 aaattgattg gcaatatatt cgatcgaatt taatgattgg aaatattgtc caagcatttt
    60661 cttcttcagc aaatcgagat ttgtttctga cacttccgga tcatcagcga atccaagaat
    60721 gatttctttg actttttctg ctgctttctc tggttcgtcc gtatctccgc tgaagtccgc
    60781 aaagtgaaat tcacgatcca agctgaattc aaaaccaaag ctgtcatcga taattccttg
    60841 attgtacatc gctagatagt ttcgagaagt attgcctaaa atcatttgga acaacagatt
    60901 gattgctgtt ttatagcgta acagttctgt tccttcttgc ggcaatgtgt ctaatccttt
    60961 aataccaagt acaaatttat ctcgtgtaat ggctgcttcc aatgcacttt gtttgatgat
    61021 ttcttttgtg ttttcaggga aataacgtac aatttcttgc tttggaggga aattttttgc
    61081 ttcttggttt tcccgaataa gtttcatcaa tttctcaggc tccatcttac caactacaaa
    61141 taaaaccata ttgcttggct gataaaacgt ccgatagcac gtatacaagt cttgagctgt
    61201 gattttgtcg atactttcaa ccgtgcccgc aatatcgata tgcaatgggt gtgtaggata
    61261 caagttattt agtatgccaa aaaacatccg ccagttaggg tcgtcttcat acatttggat
    61321 ttcctgaccg atgattcctt tttccttgtt tacagtttct tctgtgaagt aaggtgcttg
    61381 tacaaaatcg atcagagtcg tcagattctt ttctacctga tccgtcgtag aaaacagata
    61441 gctggttttc gtaaaacttg tgaaagcatt ggcggaagct ccttgtttcc caaataattg
    61501 aaagacatca ccatcttctt tttcaaacaa cttatgttct aaaaaatggg caattccatc
    61561 tggaactttc accttttctt tttcaccata gggaataaat tcgttatcga tcgaaccata
    61621 attcgtactg aacaaaccat atgtcttgtg atagtcattt ttaggcaaca aatacacggt
    61681 caaaccgttt ggcagtactt catgataaag tgtttcattg atttgctcat attctgtttt
    61741 attcatttgc atttcctcct gctaaaaaga agattgcctg caattcgatt tgctcagcta
    61801 cttgttgtat ctctttgatc gttacgctct ccatacgttt caaccattct tcatcagata
    61861 attttgtttc cggcagccag ctgtccaaaa aagaagcttc gattgccgct tgcggagagt
    61921 ctagagaaag cagatattgg tttctcagca ttgcttttgt ctgagacagt tccaactctg
    61981 ttatttcacc atttcgcaaa ctttctaatt gctcgtgaat cagatgaagt acttgatttc
    62041 ggttcttttc atcgataccg gtttggacac tcatgaatcc tcggaacgta tccacgctac
    62101 tagaggcata ataagctaga ctttctttct ctctgacatt catgaaaagt ttagagtgag
    62161 gaaaaccgcc aaataaaccg ttaaagacca ttagcgcaaa acgttctggt tcatcgtaat
    62221 acacatttgt ctgataagct aggttcagct ttgcttgaac gattggctca cgtacttgtc
    62281 gttccttcac gatattcact tgaggttggg tataaaacag atctggataa actgtttccc
    62341 gcgactcaaa tggtaattgc ccaactgctt cagctgcttt gtccggatca acatcgccga
    62401 caacaaaaat gtcgatttga tcatttgcca tcatttcttg atagtaggac gctagcgaac
    62461 tagcagtgat cttgtccaaa tcttcgacta cgcccaaccc tgggatcttt tgttccgggc
    62521 tgttttcaaa ataaagttct tgcaaggcat aggaagcaaa agtttgttta tcttccttca
    62581 aactttccaa atatagacgc agattgttct tttccaagtc aaacgtcaac tgatcaaact
    62641 gatgattttt aatatttgga taaaataaaa cctcttttaa aaaatctacc gcttgagaaa
    62701 aaaggtttgg atcattgaca tattcaccat tcacaaaact gatccctgcg tttagccaat
    62761 gtaaatttcc tttttttcta actgataatc caaagcttgc gccataaagc tctgcaagtt
    62821 gcgcacttaa ctttgtctga tccgaataat tcaaactatt tgtttccaac atgctgctga
    62881 gaagtgaacg tttcgtgatg acttcttgtt gcagacgcgc agtaaaacgg ataaaaatcc
    62941 ggatcgtttt gtattgtttt gttggtaaga catgaagatt cacgccttct gccaattgat
    63001 acaccatatt tatatgctcc ttttcacagt tgattgcccg cttactcttt taatgggtca
    63061 acctgccttt tttacttatt cctctgcttg aaatttataa gttcaggcaa ttcgccgttt
    63121 tttctaaatg atgttacact ttatagtata gcatagatgt tttttatcaa aagaaacaga
    63181 cggctaaaag cgtatattgt ttttttattt tttatttttc gatatactaa agacaaataa
    63241 aagaagggag ggtcattcat gatcaaagaa ttcaaagagt tcatcatgcg tggagatgtc
    63301 ttggatcttg ctgtcggcgt tgttattggt agtgcgttta caagcatcgt aaaccaagtg
    63361 gtgcaaggct tgatcacacc actaataggt tggtttgtcg caatgatcac aggtacttct
    63421 gatttagaag gagcactttc aattcttgac tggtcgccga caaaaggcgt cacatttgcg
    63481 tttggtaacg ttattagtgc tatcattaca tttctgatca ctggttttgt cttattctta
    63541 gttgtcaaag cggcaaaccg tgcgaagaat ttacgctcca aagaagagca agtggaagtg
    63601 gaagaaactc ctactgcaga agattatctt agtgacatac gcgatcttct tgccaaacaa
    63661 gtggcagaag acaatacaca tccagtagag caaacaaatc tttccgatac ttctaaataa
    63721 taaagaatct aaaaaaaaga aagccgattt tcagtgtcgg ctttcttttt ttagattctt
    63781 aacttgctac ttgttccttt ttcatgtcga tatgtggaat atcatcttcc aaatacacat
    63841 ctgagattgc cttgaatcca aacgactcat aaaaagcttg taggtattct tgtgcgccga
    63901 tcacgattgg tttttctgga aaatttttct ggatcatgtt aatcgtttct tgaacaatct
    63961 ttcttcctaa accatcttta cggttgtcct gatgaacaag gacacgtcca aaatggatac
    64021 tctccgcttc ttcatatact cgcgtgtagg caaggatctt cccatcagta tcttgaaaaa
    64081 acgtatgcca agcttctcca tcaatgtcat caacttcttg ataaggacac tgttgttcca
    64141 caacaaaaac tgcgattcgt tctttgacga tcgcgtaaaa ctctgctgtt gacaattctt
    64201 caaatttctt tacctgatat tccactaagc aaacgccccc tgctttttta ttcttagcat
    64261 accgattcgc acacaaaaaa gcaaacgaac cttacgaatc tcaggctcgt ttgcttttta
    64321 aactgcttca gttaaaaatt cgatctcaac tgtccgagta agtacatctg aatagctgta
    64381 agatactcgt tcaaaagaat tttcttcagg atccaaatca acaacgaata ctgaaggata
    64441 ggtttctgtt aaaacgccgc ggcgttctgt ttgacgcttt cttcctgtct gagcaaccaa
    64501 catgattggg ctgccgatac gaccttctaa atctttcttg attgaagcta aagttgttgg
    64561 catacagttc acctctacta tcaactatac cacatatttt taaaattttc aagtttacca
    64621 taaaaaaaaa agaaatgcaa taaaaataaa taagaagctc attaagattt ttctaaatta
    64681 ttcctcatta taaaatttca agtgtttttt tattttgagt tttactctcc cgtaagcgct
    64741 cattacttgc ttgtgatcca ttgctaaaca ttcagccatg tctacaaaat caacgccttg
    64801 catataataa tgaaaaattt tagcttctat ttttgaaaac tggatttcgc aattttcgat
    64861 tgcttctttt aataaaagat gctgaattgc taaaggttct tgcaatgtga tctctgctaa
    64921 aaagtctggt ccttctgtct ctattttttg gtcgattgag acttcatctt tttgatcacg
    64981 acgcttcagc gcgttctgct tcctcaacag agaatagatt tgattgctta taacgctttt
    65041 ataataactt ccaaagctaa cacctttgct tttttcgtaa gttctcaatg cctgatataa
    65101 agcgatcctt gcttcttgtt cccaatcctc agaaacataa tttcttaaat aataggtgtt
    65161 tttcaaacgt agtaaaagtg gaaaatattt ttgatacagg gcagcaaatg cttcttcgtc
    65221 accattacgt gcagcgcgca ataactcctc agacataaaa taattcctcc ataaattcgt
    65281 ttatggagga atcttatcat caatgattca tcgaactgat tagaacgata tgttatttat
    65341 tttttctcat taaatcgtcc aatttttggg acaatttttt taactgctct tcattccatg
    65401 gagaattacg tcggaaatca ataaaatgca tatctttatt ttcttgggct attgtttttt
    65461 ccgttttttt tatcgtctta tataattcat aagcagaagt tcgtaatgct ccttgggaaa
    65521 agatcatcca ctgttctgct aaatcgcttg tcgccactgt cacttgtgtc aaacggtcat
    65581 tcagctgacc agcgattctc tcgatataac tgtcagccgt ttcgtcttct ttcgtaaaaa
    65641 caacatccaa ctggtatttc ttataatttt gttggatgcc cggaactagt tgggcatcga
    65701 agacaacgat gacttccatt ccttcatatt tcgcataatt tgataaacga tgtaaaagag
    65761 cttctcttgc atccgccatt ttgtcctgct ttttaagctg gacaagttcc ggccacgaac
    65821 caatcatgtt gtagccgtct acaatcaaca gctgtttttt catggtctac tccccctgac
    65881 gttgggaaaa agcctgatac ataagcaaac cagcagcaac actggcattt aagctctgga
    65941 cgtgcccggt catcgggatc gtcagcaatt catccatttc ttttttcaat cctggactca
    66001 ttcctttgcc ttcattacca atgactaaag caattgatcc tttggcattc catttttgga
    66061 agtttgtgcc ggtcatatct gtgccaaata cccaaaatcc tgtttctttg agctgttgca
    66121 cagcttgtac caaattcgtc acgcgtgcaa cagggacatg ttcgactgcc ccagtggaag
    66181 tctttgttac gataggtgtg attccaactg ctcggtgttt tggtatgatc acaccatcga
    66241 cgccacttgc gtctgctgtc cgtaaaatcg acccaaaatt gtgtggatct tcgatgctat
    66301 ccaaaatcaa aaagaagggg tcttcttttt tctcttttgt tcgttcaatc agttggtcaa
    66361 gggataaata ttcataaggt gtaatcgcaa gaacgactcc ttgatgcacg ccgtgatcgc
    66421 tcaaagtttc taatttttgt ttaggaaccc atttgactgg cacagcttgt tcacgtgcga
    66481 tttctttcag ttcttctact ttttctcctc gtgaatcttc ttgaagaaag agtttattcc
    66541 ctcgcccttg ttgtagcgct tctactgcgg catggtgccc aaagacgaaa ttatcttcta
    66601 atgcttcttc attttgatca gaaactgact gatttcgtcc agtttgcttt ttatttgaat
    66661 atctattttg ttttttgtct tcaaatccac gtttcgattg atgtttgttt gttctttctt
    66721 tacccatttt tttcaccaac tttctgaata caccagcgga tcaattcttc catccgctcg
    66781 gtttgttttg tcaaatgcag atagcccatg agcgcttcga accctgttgc gacccgatac
    66841 gtcgtaacat cagcattttt tgcgctcgta tggcttttag catttcttcc tctgcgataa
    66901 taaagttctt cttcttctgt caaaagatgt tcttccagca tttgctgaat caaaaaggct
    66961 tgtgcattcg cagaaacata attcgttgcc gcacgatgca gcttattggg ttttgtttct
    67021 ccttgatcaa tcaggtggtc acgaacatag atttcgtaaa tcgcatctcc aacataagcc
    67081 aaggctaaac cgttcaattg tgtgtaatct ctcatgcttc tcttctccat cgggttcctt
    67141 gcggtgtatc ttctaataag atcccttttt ctttcaacaa atcacgaatt tcgtcgcttc
    67201 ggacaaaatc acgattgctt cttgcttgat ttcgttcttc gatcaattgt tcaatctctt
    67261 catctaataa ctcttctgct gtaaataaaa taccgaagat cgaaagccat tgcgagaata
    67321 aagcttctcc ttgtgccaag acagcggcag aaactttcgg ctggtctaga taagtgttca
    67381 gccacttagc aagctcatag accactgtga tcccatttgc tgcattaaaa tcatcgtcca
    67441 tttcttcgat gaatcgctgt tctaaatttt ctaacaaagc gattttatcc gcatcatctg
    67501 ccaaattctc tgaggcagtt tcttggcgga atttcaaatt gtcaaacgta ttcttcagtc
    67561 gttgtaaatt ggtggctgct tctttcatcg tcgtttcact gtagcggatc ggacgacggt
    67621 attgtgtggt cgccatgaag aaacgcaaga cttgtggatc aacgtttttg atcatttcat
    67681 gtacagtgat gaaattccct agagatttac tcattttttc atcgtcttcg ccaatcgtta
    67741 catagccatt gtgcatccag taattagcga attttttccc tgttttcgct tcactttgtg
    67801 cgatttcatt ttcatgatga ggaaattcta aatcttgccc gccaccatgg atatcgatcg
    67861 tttctcctaa atgttttgtt gccataacgg aacattcaat atgccaaccg ggacgtcctt
    67921 tgccccatgg tgaatcccaa gaaatctcgc caggttttgc ttgtttccat aaagcgaaat
    67981 ctaatgggtc ttctttttgc tgctgttctt cccctgtacg ctgacttgct ccgacttcca
    68041 gttcatcgat ggattggtca cttaatttcc cataattttc aaatttacgg gtacggtaat
    68101 acacatcacc tgaagattca taagcatagc ctttttcaac caacacttga ataaatgcta
    68161 aaatatctgg catatgatcc atgactcttg gatgcagtgt agcaggttcg acattcaacg
    68221 ctttcgtatc ttcttcaaat gctcggatga aacgatcagc aacttctggt gctgtaatac
    68281 ctaattcgtt tgctgtacgg atgattttat cgtctacatc cgtgaaattc gatacgaaat
    68341 cgactttata gcctcgatat tcaaaatagc gtcgaattgt atcgaaagca atggtgctac
    68401 gagcatttcc gatatggata taattataca cagtcggtcc gcagacatac ataccgacat
    68461 gtcccttttg tatagggatg aattcttctt tttttctggt caatgtattg tagattttta
    68521 tcattctgat ctcctcactt tttctccttt gattcgaacg acttttgctg gtactcctac
    68581 cgctgtagcg tcgtctggaa catctttcaa cacaacggca cctgcaccga ttttggcgtt
    68641 ttttccgatc gttaccggtc ctaatatctg cgcattcgca gagagcatgg ctccttgttt
    68701 aacagttggg tgtcttttac ccgtttcttt tcctgtgccg cctaatgtta cgccatggaa
    68761 taaaatcaca tcgtcctcga tttctgcggt ttcgccaatg acgattccca ttccatggtc
    68821 gatgaacacg ccagttccaa tcgttgctcc tggatggatc tcaacaccag ttaggaaacg
    68881 ccagaattga gcattgatct tcgccaataa aaagagccgg tgctgatata aaaaatgaga
    68941 gaaacgatgc caaaacaagg catgaaaacc agggtatgtc aaaacgatct cagctgtcga
    69001 acgtgcagcc ggatcgtttc tctttgctgc atcaatcgct cgggtaaacc aactcatgac
    69061 tttccactcc tttcgtaaga attttatgta ggaaatcatc ttcttataaa gaaaagaagc
    69121 gccttttaaa taagtttcct tatcaaaaga cgctttccgc gtggttccac ttttcttcat
    69181 aatcaatgat tatctctgac agctaacgcc tgttatacgt tcttggctac tttgtttcct
    69241 ataaaacagt ttttcctgtt ttctgtgttt cgccaagacc actcccagag gcatttcggc
    69301 aaccattcat tgataccttg caccacccgg tatctctctt gtaatgatca gctgcttact
    69361 tttttctgtt catcgtgttt agttcagtac ttgatttaaa tgtgctaatg atttttcacg
    69421 accaagcaat tcgatcgttt caggcaattc tggaccatgc atttgtcctg atacagctac
    69481 acggattggc atgaaaagat tttttccttt tacgccagtt tctttttgaa cagctttgat
    69541 ggcagctttg acagttggag catctactac ttccatttgt tctagctgtg ctttgaatgc
    69601 gtggagaaca gtaggaactg tttcaccagc aagtacttct tttgctgctt cattcaatac
    69661 aggatgttca ttgaaaaata gcgtagacag atcaacgatt tctgcagcat agctcatttg
    69721 aggttgatac aggctaacga tcttcttcac ccattcgatt gtcttttcat ctgggttttc
    69781 tgctacacgt ccatcagcga ttagataagg cagacacatg tcagtaaatg catctagatc
    69841 cattgctttg atgtaatggt tgtttaccca ttgcagtttt ttcgcatcga aagctgcggg
    69901 tgatttactt aggcgttttg gatcgaacat tttgatcaat tcttggtgtt cgaagatttc
    69961 gtcttcgccc acaggtgacc agcccaataa tgcaataaag ttgaacattg catctggtag
    70021 atagcctaat tcgcgatatt gttcgataaa ttgcaagatt gattcgtcac gtttgcttag
    70081 ttttttacct gtttcactgt tgatgatcaa tgtcatatgt ccgaaggttg gtggtgtcca
    70141 gccaaatgct tcatagatca tcagttgttt tggtgtattg gcaatatggt catctccacg
    70201 taaaacgtga gtgattttca tcaaatgatc atcgaccgca acagcaaaat tataagttgg
    70261 cataccatcg cgtttttgga tgacaaagtc gccaccgata ttatcggatt cgaacgaaat
    70321 agcgcctttc accatatctg taaatgcgta ttctgtattg cgaggcacac ggaaacgtac
    70381 aacagattct agaccttgtg cttctttttc tgcttgttct tcaggtgtca agttcgcaca
    70441 tgttcctgcg taatgaggca tttctcctct tgcgcgttgt gcttcccgtt ctgcttctaa
    70501 ttcttcttct gtgcaatagc atttgtatgc tcgattgcta gcaagcagct gatcaatcag
    70561 cggttgatag atttctttac gttcagattg acggtaaggg ccgtattctc caggattttc
    70621 aggagattca tcccaattca ttcccaacca agcaaggttt tccaactggc ttttttcgcc
    70681 atcttcgata ttacgttttt ggtcagtatc ctcaatacga ataataaagt ctccatcatt
    70741 gtggcgggca aacaaataat tgaataatgc agttcttgca tttccaatat gcaggtgccc
    70801 agttggactt ggtgcatagc gtacgcgtac tttcgtcatt ttcttcctct tctttcaaac
    70861 tagactttga ctaacagcaa aaattccgtc agttacggct tctcaaatat catttattta
    70921 aagccactca gcacaaattt taccttttct aaggtaaata gtaaagccaa ctggttgaat
    70981 ttccttacca gttggctgaa tttctttttt attttgattg tttagtcttt ttctctgtct
    71041 cttttttatt gtcgattcct cgtcctgcat gtgcaggttt agcaaagatc atgcgtccag
    71101 cagctgtttg aagggcactt gttacaacga cttcgatacg ttcattcatg taatgctgtc
    71161 catcttctac gacaaccatc gtgccgtcat caaggtaggc tactccttgt tggcgttctg
    71221 tcccggcttt tactactaga acattcatcg tttcaccagg gatgacgact ggttttacgg
    71281 catttgccaa cgcattgata ttaagaacag gtacattttg gaattcagag actttattca
    71341 agttatagtc attggttaca atgacaccat ctaaaagctt agccaatttg atcaatttgc
    71401 tgtctacttc actgatatct tcaaagtctc catcgtacat ttcgacagat ataccctctt
    71461 ctttttgcaa ggcatttagg atatctaatc cgcgacgacc acgcacacgt ttcaaactat
    71521 cccctgagtc cgcgatgtat tgtagttcgt aaagaacaaa attagggatc atcaaggttc
    71581 cttctaagaa tccagtcttt gtaatatcat aaatccgacc gtcaatgatc acgcttgtat
    71641 ccaagatttt atatttatgg aaattttctc ctgattttcg ttctaacagt tgactctcaa
    71701 cttgactagc tgtttcttgc tcgatttttt tgcttcgtga accaaaaact ttcttccatt
    71761 cttcgattcg tgtcgttccc attctcaatc ccagatagcc taagatgatc atcagtaaaa
    71821 tcggcaatac actattgacg aatggaattt ccatattgta aagaggggtc gagatcacaa
    71881 cacctaaagt caatccgatg atcgcaccga tcgcaccgaa gagaagataa gtcaagctga
    71941 cctcacttag tttttgttct acttgtttga taatagctga gatatgtttg gccaacagca
    72001 aagataataa aaagaaaata agtgcgccta acaggctgtt ggtaaatgta ttattcagcc
    72061 atccgtttga ctgttgaccg attgcctgcc aagctgaggg taaaaatgaa atacccaagc
    72121 ttgcgccgac aatgatcatc agcaaagtaa tgacacgttt ttgcatcgtt tttcctccgt
    72181 ttcgacaatc atttattagt tagcggaaca cacgcttcaa cgtttcagcc aaagttgcta
    72241 ctccaactat ctcgattcct tttggcgctt cccagttacc taagttgttt ttaggtaggt
    72301 atacttttgt gaagccgagt ttttggactt ctttgactcg ttgttcaata tgactgacac
    72361 gtctgatttc tccagtcagt ccaatttcac cgatgaaaca ttccgttggc tgtgttcctt
    72421 tttctttata gcttgaagca atactgacag cgatagctaa atcaatcgct ggttcattta
    72481 attttacccc acctgcagct tttaagtaag catcttgatt ctgaagaagc aacccagctc
    72541 ttttttccag cactgccatg atcagagata cccgattgaa atcaagacct gttgttgttc
    72601 gtttggcatt tccgaacata gtaggtgtga ctaatgcttg gatctctacc aaaattggac
    72661 gtgtcccttc cattgccaca acgatagcag agccagttgc accgtctagg cgttcttcta
    72721 agaaaatctg tgaaggatta gcgacttctt ccaatccatg ctcatgcatt tcaaaaatcc
    72781 caatctcatt cgttgagcca aatcggtttt ttactgctcg caaaatccga aaactatgat
    72841 gttgttcacc ttcaaaatat aacaccgtat ccaccatatg ttctaacatt cttgggccgg
    72901 cgatcgagcc ttctttggta acatgaccga cgataaaaat ggctatccca tttgttttag
    72961 cggttttgag tagttctgca gtggtttctc ttacttggct gacacttcct gccacacttg
    73021 tgatgtctgg ctgcgtcatc gtttggatgg aatcaatgat aacataatca ggggagatat
    73081 gttcgatggc acgactgatt tcgttcatat ctgtttcagc gtatagataa aattctgtgt
    73141 tgatacttcc gaggcgttcc gcgcgtaatt ttatctgctc tgcgctttct tcgccggata
    73201 catataagac ttttccgcct atggctgcta attgctgaga aacttgtaac agcaaagtgg
    73261 atttcccgat acctggatcg ccaccaatca agaccataga ccctggcacc acacctccgc
    73321 ctaacacacg gttcagttct tctaattttg ttttgatccg aggttctttt ttagggacga
    73381 cgtctgcgat ttttgttggt tttgcttttt ctcctgtcaa acttgtccga gttctgcggt
    73441 ccgttgtatc ttgttcgatt tcttcgacca tcgtattcca ttttccgcaa tttgggcagc
    73501 gtcccaagaa cttaggcgac acatacccgc aattttggca aacaaattgt acttttgatt
    73561 tttttgccat tgtaccgcct ccttttatcc taatcatgag acattaaatc aagcttaagt
    73621 atctttaacg ttttatttac tggaagaacc aaatccgcct tgacgttgag cagtcgtttg
    73681 atcttgatct gcttttaaaa acggcaaaaa gatcccttgg ccgatacgct cgcctttttt
    73741 gatcactaca tccttgaaac caaagttggt gaattggaac atgatatggc cttcatttgc
    73801 ctcattattg taataatcac tgtcaatcac acctactccg tttgtcaaca ctaaaaaccg
    73861 cttcaacgga ttgcttgaac ggttagcaag ctgcaaaaat tcatcttctc ccatgtaagc
    73921 tttgattcca gtaggcacga gggttggttt caattgtttt tcattttctg atacatcttt
    73981 tttcaatcca tctgcgactg tttccaaccc ctttttccag cctgctttcc agatacttgg
    74041 aatcacgacc tcttctgctg cttcaaaatc atagccagca gcatgatgtg tagcgcgctg
    74101 cggtagattg atattttgat ctttatattt agaaataact tcaaatcctc tttttctcac
    74161 cggttttcct
//
LOCUS       DAZULR010000008        73772 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.008, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000008 DAZULR010000000
VERSION     DAZULR010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 73772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73772
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.008"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..561)
                     /locus_tag="ACG8ZV_000568"
     CDS             complement(<1..561)
                     /locus_tag="ACG8ZV_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HFS4995938.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKVFFKLKMNNL
                     NVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTENLSKT
                     IEQIKIDNLLSQNYDPEIYLFLYENKI"
     gene            1255..1641
                     /locus_tag="ACG8ZV_000569"
     CDS             1255..1641
                     /locus_tag="ACG8ZV_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFS4995939.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            1735..1926
                     /locus_tag="ACG8ZV_000570"
     CDS             1735..1926
                     /locus_tag="ACG8ZV_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4995940.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            2440..2772
                     /locus_tag="ACG8ZV_000571"
     CDS             2440..2772
                     /locus_tag="ACG8ZV_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFS4995941.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            2682..2876
                     /locus_tag="ACG8ZV_000572"
     CDS             2682..2876
                     /locus_tag="ACG8ZV_000572"
                     /inference="COORDINATES: protein motif:HMM:NF024673.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFS4995942.1"
                     /translation="MFYEHKDRYGSPGITQKLYDEGIEINKRVVAVLMREMNLCTRGF
                     HRRKSSHGREKTIKEMVKKC"
     gene            2915..3061
                     /locus_tag="ACG8ZV_000573"
     CDS             2915..3061
                     /locus_tag="ACG8ZV_000573"
                     /inference="COORDINATES: protein motif:HMM:NF012870.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995943.1"
                     /translation="MMDITYIPCNDGRLYLSTYIDLATRILRYYMVDSHMKKEIVVRP
                     LQIY"
     gene            3499..4839
                     /locus_tag="ACG8ZV_000574"
                     /pseudo
     CDS             3499..4839
                     /locus_tag="ACG8ZV_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(5080..6696)
                     /locus_tag="ACG8ZV_000575"
     CDS             complement(5080..6696)
                     /locus_tag="ACG8ZV_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFS4995944.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            6814..7032
                     /locus_tag="ACG8ZV_000576"
     CDS             6814..7032
                     /locus_tag="ACG8ZV_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4995945.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            7227..7688
                     /locus_tag="ACG8ZV_000577"
     CDS             7227..7688
                     /locus_tag="ACG8ZV_000577"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFS4995946.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(7881..8120)
                     /locus_tag="ACG8ZV_000578"
     CDS             complement(7881..8120)
                     /locus_tag="ACG8ZV_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4995947.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(8144..9667)
                     /locus_tag="ACG8ZV_000579"
     CDS             complement(8144..9667)
                     /locus_tag="ACG8ZV_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HFS4995948.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            complement(9685..9807)
                     /locus_tag="ACG8ZV_000580"
     CDS             complement(9685..9807)
                     /locus_tag="ACG8ZV_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HFS4995949.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            complement(9837..10820)
                     /locus_tag="ACG8ZV_000581"
     CDS             complement(9837..10820)
                     /locus_tag="ACG8ZV_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFS4995950.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            complement(10844..10993)
                     /gene="rpmG"
                     /locus_tag="ACG8ZV_000582"
     CDS             complement(10844..10993)
                     /gene="rpmG"
                     /locus_tag="ACG8ZV_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFS4995951.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            complement(11014..11391)
                     /locus_tag="ACG8ZV_000583"
     CDS             complement(11014..11391)
                     /locus_tag="ACG8ZV_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995952.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            complement(11423..11602)
                     /gene="rpmF"
                     /locus_tag="ACG8ZV_000584"
     CDS             complement(11423..11602)
                     /gene="rpmF"
                     /locus_tag="ACG8ZV_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HFS4995953.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            complement(11617..11886)
                     /gene="rpsN"
                     /locus_tag="ACG8ZV_000585"
     CDS             complement(11617..11886)
                     /gene="rpsN"
                     /locus_tag="ACG8ZV_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HFS4995954.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(12409..14175)
                     /locus_tag="ACG8ZV_000586"
     CDS             complement(12409..14175)
                     /locus_tag="ACG8ZV_000586"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4995955.1"
                     /translation="MQMIGGLTMKSFYKNKFALSDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENTKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(14135..15889)
                     /locus_tag="ACG8ZV_000587"
     CDS             complement(14135..15889)
                     /locus_tag="ACG8ZV_000587"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4995956.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLIKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(15999..16568)
                     /locus_tag="ACG8ZV_000588"
     CDS             complement(15999..16568)
                     /locus_tag="ACG8ZV_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HFS4995957.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(16586..18001)
                     /locus_tag="ACG8ZV_000589"
     CDS             complement(16586..18001)
                     /locus_tag="ACG8ZV_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4995958.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            complement(18012..18680)
                     /locus_tag="ACG8ZV_000590"
     CDS             complement(18012..18680)
                     /locus_tag="ACG8ZV_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HFS4995959.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFATSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(18810..19394)
                     /locus_tag="ACG8ZV_000591"
     CDS             complement(18810..19394)
                     /locus_tag="ACG8ZV_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFS4995960.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLI
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(19725..19958)
                     /locus_tag="ACG8ZV_000592"
     CDS             complement(19725..19958)
                     /locus_tag="ACG8ZV_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HFS4995961.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(19973..20923)
                     /locus_tag="ACG8ZV_000593"
     CDS             complement(19973..20923)
                     /locus_tag="ACG8ZV_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein"
                     /protein_id="HFS4995962.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSINSKDKDKVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(20920..21762)
                     /locus_tag="ACG8ZV_000594"
     CDS             complement(20920..21762)
                     /locus_tag="ACG8ZV_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HFS4995963.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVIVVLFFKELLIT
                     SFDPLMAKAIGMNVSFYHYLLMVLLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGASSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERSL"
     gene            complement(21764..22483)
                     /locus_tag="ACG8ZV_000595"
     CDS             complement(21764..22483)
                     /locus_tag="ACG8ZV_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFS4995964.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKKLKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGE"
     gene            23031..23333
                     /locus_tag="ACG8ZV_000596"
     CDS             23031..23333
                     /locus_tag="ACG8ZV_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003013637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4995965.1"
                     /translation="MTIAANNDTSVRLAVNWGEVKFLCAYPKQFKNFITTILGDDFIE
                     SRVYLNKKQTCAFLGIDNNTLDKWIRIYNFPVIRVGGVVRFDVEDIKDFMNTFKIT"
     gene            23405..24631
                     /locus_tag="ACG8ZV_000597"
     CDS             23405..24631
                     /locus_tag="ACG8ZV_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4995966.1"
                     /translation="MPTKLSNGKYKTNLRYPKRFKEITGIASEKYQKTFPNRQLAIKA
                     ENDMKKKIEKVLREENANSLELKGKITFKKFYESKWLPRYELGQTIRSNRPPSDITIS
                     NTKDIFRLHILPMFGEYAMNYLNINTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQSITAPKKNALEEKRIQEGKQALSSKELTNWIEAVNDDFNNHLL
                     TFHDYTLFMITLYLGDRKSETYALQWKYIDFEKQTVRLKHTLDKYQRKKFTKGRKDTV
                     IQVPEVVMTLLSEWKSVQADQLLKLKIKQTLDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPDLVHLSPHKLRHTYATIARQGGADMNQISNALTHSDISTTKIYVNTPDIV
                     DKAVFEAFQRGLNKCD"
     gene            complement(25220..26668)
                     /locus_tag="ACG8ZV_000598"
     CDS             complement(25220..26668)
                     /locus_tag="ACG8ZV_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013189598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFS4995967.1"
                     /translation="MDYEIQKFISEKEDQYFDRKSARIKPRDIIKHIVAFANADGGKL
                     VIGIEDDGTISGFKFQGAIDPDEYVLAINSMTKPNPTFKKEMKSIKNARGEDDILFII
                     DVEPSISHVIFNSNGDCFLRIGDKSVHQTHDQISKLEYDKGQRMFEDIEILDSTLDDI
                     DESLMDSYKKLKKAEAISTETILTGRGLMRNGHLTNAGMLLFGKNTFLALPNSRIRFL
                     RYDGKRNETGRRLNIVKEFDYEGAIPKLIESITRDVKTQLREFQYLNDDGKFSIIPEY
                     PEFAWFEGIVNALTHRDYSYKGDYVRINMYDDRLEIFSPGALPNIVTLQNMRRTRYAR
                     NPRIARTLSEFGWVKELNEGVNRIYDEMQLLFLNEPKYSEPNNNSVLLVLENSITSRH
                     LRERDRLDDYLGEFEVDSLSTSEKMIVSHLFNNEKISVKEASEVLKKGVGYSRKVLKE
                     MLRKKIIQWHGTSTKDPTQYYSLNRVKQSKIE"
     gene            complement(26814..28310)
                     /locus_tag="ACG8ZV_000599"
     CDS             complement(26814..28310)
                     /locus_tag="ACG8ZV_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
                     /protein_id="HFS4995968.1"
                     /translation="MNHQEAKQFFLKTSSFFSTSLPNYIDLSVGIEKAVDLLKNKSFT
                     ELVRHKRSLSEAVDVNHRILANKDGNYAWRPLQILHPLVYVDLVNGITQKNNWNHIKN
                     KFEEFQADKRIECISLPVESISSKSDTAETILNWWENLEQAQISYALEYDYCIHSDIT
                     DCYSSMYTHTIPWAVHSKEWAKTHRKDTQGVGNLIDSKIRYLQNGQTNGIPQGNVLMD
                     FVAEIVLGYADKMLLNKIEKTEIKEFKILRYRDDYRIFSVRKDQAEVIIRLLSEVLSD
                     LNLKLNSNKTFLSDNIILDAIKPDKIYWDLKHASFTEKSNNKWKFKLSLQKHLLQVKL
                     LGDKYPNCGSLSKALSEVYTHRVSTLNKRPDDIYQLISILVNIMQKNPRTLEACIVIL
                     GKLFEFIAVEEINLYLDKILRKFVNTPNTDIVEIWLQRLSLIHSREKSYSAKLCKKVS
                     NPKGFTLWNSDWLKKGFDESGIVNETFISNLSLTTPAKDLELFISQYE"
     gene            complement(28482..28727)
                     /locus_tag="ACG8ZV_000600"
     CDS             complement(28482..28727)
                     /locus_tag="ACG8ZV_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFS4995969.1"
                     /translation="MLFLKEEKIIDKENVIGSNIRRIRLEKGIGQTELIRDLQLHKIA
                     ITRETLVKIEGGRQHIKLDQLRAIRDILQVSYEDLLQ"
     gene            28832..29605
                     /locus_tag="ACG8ZV_000601"
     CDS             28832..29605
                     /locus_tag="ACG8ZV_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995970.1"
                     /translation="MKKFAIILTCALLIGTISGCTTSETSSTSTETSTTTSEKNYPIH
                     FFPVPDGFEAYYHDKKLDVPLSETESTEKILPIEIERNQDDIKLKADLPLLNSTQIDR
                     HENIKVNIEKGALAKLYTEKVEQFFKSGANKDFSKISDYSENFFNETQDEIMNSTFMA
                     EDMYNMTLKKIKAYDHPLNLTLNNGLLSFVLAGYVDYEYSPDYLEKPLQHENNDINFR
                     FVYESKSKTWLVDQLSTINTSFHELPKPENEVEMVIKIF"
     gene            complement(29835..30083)
                     /locus_tag="ACG8ZV_000602"
     CDS             complement(29835..30083)
                     /locus_tag="ACG8ZV_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFS4995971.1"
                     /translation="MDTITPTNFKENIGKVLQEVVHSNSEIEITRDSKNGLNDGVIMI
                     SKRKWELLQEELYLQRTGTWAYVSDLMKNEKEDDFKVV"
     gene            complement(30182..30496)
                     /locus_tag="ACG8ZV_000603"
     CDS             complement(30182..30496)
                     /locus_tag="ACG8ZV_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995972.1"
                     /translation="MTEENKVDLLETLVINKKEFEQLFLDFFVQYDRIYDFNSSLDLF
                     ELEAEIIENSREKNGKIIISVEKFNELFSETFEIDADYYQPQEVFREFRNKIIGFSQT
                     TK"
     gene            complement(30573..31067)
                     /locus_tag="ACG8ZV_000604"
     CDS             complement(30573..31067)
                     /locus_tag="ACG8ZV_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995973.1"
                     /translation="MFKVYFPFQWLVKGIFFVLLGLILFGSYLTIKARYFPEEKPIKI
                     VTKDLKIGETYQADGVELTFKNIELTEKRNEFAQHDRVLQVTYTMKNDTENPIRPQQW
                     SIENKDGEELYEYAMILDNPEYIESGKSETVNYYYELPIERQDYQIVVRRANGYFVGL
                     PFNL"
     gene            complement(31060..31362)
                     /locus_tag="ACG8ZV_000605"
     CDS             complement(31060..31362)
                     /locus_tag="ACG8ZV_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995974.1"
                     /translation="MSDPYIKVYCSKETKKLFDSFYEKNKGTLGTKANMFRVMVSNLP
                     MLASQSNKKFSDPESIKLEQTISELESSIMKKLDGIDQKLSCSLKTKYKTEEKKDV"
     gene            complement(31385..32722)
                     /locus_tag="ACG8ZV_000606"
     CDS             complement(31385..32722)
                     /locus_tag="ACG8ZV_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HFS4995975.1"
                     /translation="MGSIIKIASKSRSIHNTISYMLNKQEDSELVTGIGVSNDLNAIE
                     EFKRTNEIFGDKGKIKLWHFTQSFDPLEDISAEKAHELGVKWAEKMFPNQSILVVTHT
                     DKGHVHNHFGISPNDQLTGKKMDIRKNDIRVLQAWNDNILIDNGINPLDMYKYNHLVA
                     DRENWKEREFRTENKISNREKIKLAVSEVAQYAKNYDDFHAELKKNHSIETYRFAKNQ
                     RIGYKLLDSEGELILKIGGKRLGQNYDMNYLDDLFTENKKAEQIQSKEVLTEIAIRHL
                     GKSLNGRADSRFNWQERAQRFELDNENIPFLRSSKDYEEFYDKYKFEIEDRIENLLDV
                     FGENKNQFFGFAVEEEPLKYKKKCVNLVYKKVVYDIAESLSTDYDQFNIQDTEPALKR
                     NFKKRYIQETKRVLYLFNRAIDDGTIEKARREYEETARGIDYQKQQNQYDMDF"
     gene            complement(32707..33204)
                     /locus_tag="ACG8ZV_000607"
     CDS             complement(32707..33204)
                     /locus_tag="ACG8ZV_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995976.1"
                     /translation="MAIDVSKLPLEERRKRYKRNEDSRRQNRPIKFRVDDYQYQELEK
                     TADIFGLSVPMYVKKIAVDNAGKSLKYTDRQYKEINFHLLAIGRNLNQLVKTANYLRV
                     QLNKKDTEIQKEEHQSVYLSFTTKQERLKRLYAEKNDLMIQIKSISDPLNRLEKELNK
                     LWARL"
     gene            complement(33353..33691)
                     /locus_tag="ACG8ZV_000608"
     CDS             complement(33353..33691)
                     /locus_tag="ACG8ZV_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995977.1"
                     /translation="MARKKQKSIADLKKELAELERKLYPELGKYVYEKTGISSVKEFE
                     ETFEINQKGTQEKWQKAVNFANSEFTLVHEFLASDQLMETKFQQFLRRKGETAYRIFY
                     REEAQEESVR"
     gene            complement(33695..33880)
                     /locus_tag="ACG8ZV_000609"
     CDS             complement(33695..33880)
                     /locus_tag="ACG8ZV_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995978.1"
                     /translation="MQLILQISTHDFLELDELCESVKKATNEKITVTNYIELMIQEEL
                     MMKNELMNELSHIQKGA"
     gene            complement(33894..36446)
                     /locus_tag="ACG8ZV_000610"
     CDS             complement(33894..36446)
                     /locus_tag="ACG8ZV_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pLS20_p028 family conjugation system
                     transmembrane protein"
                     /protein_id="HFS4995979.1"
                     /translation="MKIIKKKIDNRKINWLLISFLILIAMIIFTSNVAEGSIFNWFDD
                     TESQTEFLTNPLYQNYLKKYNGNFYSQFGMWIGWSVIKSMFAVVDGIQNMIPEVLDLF
                     SFVESAGLNKVYQSVLNTVVIGLMVLSLVIIGYKMVTGKGTVDLKSVGMNVVMSIVLI
                     LLMPTLIGSTEKLSGIMFAKTLYNDATSINNQDGGVAWSLIEQGVTDLAYINKTDQYS
                     MIDKTNDRNNLTKENFWKTDLTQVLTDNVIDKMEKENSTADNLRYELVENSDNEFVAT
                     KFSDNFLSTFVDGIKSGYYRYQANLWGISFGLIALAVAYVFSAFIIITAILELAFKRV
                     LGVLVFATDLETGQRSKQVLSDILQCYLTVGFQGFGLSMFAMFINYLNTGEGISTNIF
                     IKTIAYICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGTGGMNRS
                     KGGKNSGGNDQTEGEERKPERNFGQSLSQKANKTGKTLGYARERGLSGLASDGATMAS
                     ERATKPFKSMRDMANDTKNKFKEGLDDGTVSAINKNSKPIVAKNKEDETGKYADSMPI
                     RLSDRKDGAKIENADRIMSSSERMREAMKNIAESNTNYASAIQQKVQQDIEERKNAMH
                     GQAKSAEELINQKRQEAKYTPEAMNREEMLRKRVEGRTGANMDEKEALTKERIQEAKN
                     SNTGLEKSVKENLQNSTSSQDRRSVDVRENLHNTTSSQSGNRTVDVRENVQSSSTGQT
                     RTVDVRLNLQDTTSSQSGNRTVDVRENVQSSAPNQPKTVEVRETRAEASQGDKTQKIN
                     IVEERKERPNEKVIVEQEVKEKKRQRFTYENNPLFQDISDKPNPLFDSLFKK"
     gene            complement(36433..36651)
                     /locus_tag="ACG8ZV_000611"
     CDS             complement(36433..36651)
                     /locus_tag="ACG8ZV_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995980.1"
                     /translation="MIENHLVDKIYCLDHNADTLELIESICSNTIVLDLRAVNDDYVT
                     HIIVNKKMAQKLSESLKKWAEGGNNENN"
     gene            complement(36644..37384)
                     /locus_tag="ACG8ZV_000612"
     CDS             complement(36644..37384)
                     /locus_tag="ACG8ZV_000612"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995981.1"
                     /translation="MREKLKKLGDKKRHTFQGTFEFNGYKKDKYKFGQEYENATFMLS
                     NLKIVQGDNLELVTDHIWMNLTKQFLKFGWLKKGDMVQFDGRIKSYSSKKGINYKIER
                     PSKVKVFRKGTEINESSALKISTRYEIVEDIKRQNREYYEARDFFFENYFSVPRYFKL
                     KEKWPEIQAVVAINENRYTSEQFKQVFKDRDSLVDLYKKIQETDKYNLQKEFYNGLVS
                     NKNRIDLNEVEGYLHKIENFDYGRGYFD"
     gene            complement(37517..38392)
                     /locus_tag="ACG8ZV_000613"
     CDS             complement(37517..38392)
                     /locus_tag="ACG8ZV_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein DnaD"
                     /protein_id="HFS4995982.1"
                     /translation="MAEKRMLAKSFLNNASFMKMSDSAKLLYVYLNTNADDDGIVEAY
                     PYTKMLGTPDDDVKILFTKGFVFFLNEDLLAFLPHWLQNQNIRIDRYKPSIYRFKLLN
                     LKPEFFSKLKPIKFDMILQSGQVEPLRVDLMEKWYPAGIPCDVKSDTQLSQDQNSQDQ
                     TNQDKDSIEEINQDQNSFFENIINQKGIQIITRLGDRYTEVQREKYLKLIASMKDSIE
                     REYKIEIRGQDYFDITNKMLTRLFNSINEKLNLGEEIDEMKFINTTARNHWEDIAKQE
                     KASRLDMLETLKKIG"
     gene            complement(38562..38843)
                     /locus_tag="ACG8ZV_000614"
     CDS             complement(38562..38843)
                     /locus_tag="ACG8ZV_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4995983.1"
                     /translation="MEQIGVSVMLNTDQTNQLKTHVFEVTKEAIDQARIDSGLERPFL
                     KGKEMAKFLNVSYGTFLKFKRLGLPIIVVDTIELYSKEEVKKWMLQHQI"
     gene            complement(38898..39095)
                     /locus_tag="ACG8ZV_000615"
     CDS             complement(38898..39095)
                     /locus_tag="ACG8ZV_000615"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFS4995984.1"
                     /translation="MFQINEDFSIRIRERRGKLMITKTKAAELIGISRQTLKKIECFE
                     VQSVSKNVYQKIIGWLLKSDY"
     gene            39262..39636
                     /locus_tag="ACG8ZV_000616"
     CDS             39262..39636
                     /locus_tag="ACG8ZV_000616"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4995985.1"
                     /translation="MTQKNRIKETREEQNLTLKELSNLSDIPYQTLRNYEIGKRKPRN
                     DEVWWKLGTILNVRGPYLKGEDSFKTNDELHIYYLKKSHTNFELSKKEEIIDIIDKLN
                     EDGLDEALRQLALLSKIDDFKR"
     gene            39726..40892
                     /locus_tag="ACG8ZV_000617"
     CDS             39726..40892
                     /locus_tag="ACG8ZV_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4995986.1"
                     /translation="MSIQKYKTKSGTRYSVRLYVRKDENGKQEYYVKKGFKTEKEAKL
                     HEARKKVEIEDMGYHRPSNDLFRTVYEEWLPSYKNRVQETTYQRTKDLFRLHILPKFG
                     DKSISKITPIYCQNAINEWAVKYTNIKQLKSYSSQIFEYAIFAELLQRNPMTNTKLPK
                     QEKKESENYFSLEELKEFLEILNKEESLKHILIFQLLITTGVRKGELSALRWADINFE
                     EQLLHIGKSYATIRTEDPNATRKTIRIQKNTKNVSSERILPIDTQTIEMLKLWKKEQA
                     EVLLQFGINANTKKQLIFTYVNANGDVNQPLHADYSNNIMRRLEKKYKFKHVTIHGLR
                     HTHATLLLEGGASIKEAQDRLGHKNAETTLNTYSHVTEKAQRNAVDKFIAYTGL"
     gene            complement(40991..41383)
                     /gene="rpsI"
                     /locus_tag="ACG8ZV_000618"
     CDS             complement(40991..41383)
                     /gene="rpsI"
                     /locus_tag="ACG8ZV_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HFS4995987.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(41399..41827)
                     /gene="rplM"
                     /locus_tag="ACG8ZV_000619"
     CDS             complement(41399..41827)
                     /gene="rplM"
                     /locus_tag="ACG8ZV_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HFS4995988.1"
                     /translation="MAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPTFTPHL
                     DTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLIETSVK
                     GMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(42361..42828)
                     /locus_tag="ACG8ZV_000620"
     CDS             complement(42361..42828)
                     /locus_tag="ACG8ZV_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HFS4995989.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(42948..44486)
                     /locus_tag="ACG8ZV_000621"
     CDS             complement(42948..44486)
                     /locus_tag="ACG8ZV_000621"
                     /EC_number="2.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046316 - gluconokinase activity [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA];
                     GO_process: GO:0046177 - D-gluconate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HFS4995990.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            44566..45252
                     /locus_tag="ACG8ZV_000622"
     CDS             44566..45252
                     /locus_tag="ACG8ZV_000622"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HFS4995991.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(45453..45980)
                     /gene="msrA"
                     /locus_tag="ACG8ZV_000623"
     CDS             complement(45453..45980)
                     /gene="msrA"
                     /locus_tag="ACG8ZV_000623"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFS4995992.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(46064..46741)
                     /gene="pgmB"
                     /locus_tag="ACG8ZV_000624"
     CDS             complement(46064..46741)
                     /gene="pgmB"
                     /locus_tag="ACG8ZV_000624"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HFS4995993.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(46738..47868)
                     /locus_tag="ACG8ZV_000625"
     CDS             complement(46738..47868)
                     /locus_tag="ACG8ZV_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFS4995994.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(47868..50051)
                     /locus_tag="ACG8ZV_000626"
     CDS             complement(47868..50051)
                     /locus_tag="ACG8ZV_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HFS4995995.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYFSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(50048..51073)
                     /locus_tag="ACG8ZV_000627"
     CDS             complement(50048..51073)
                     /locus_tag="ACG8ZV_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFS4995996.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(51118..51945)
                     /locus_tag="ACG8ZV_000628"
     CDS             complement(51118..51945)
                     /locus_tag="ACG8ZV_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFS4995997.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(51942..53009)
                     /locus_tag="ACG8ZV_000629"
     CDS             complement(51942..53009)
                     /locus_tag="ACG8ZV_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HFS4995998.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(53035..53871)
                     /locus_tag="ACG8ZV_000630"
     CDS             complement(53035..53871)
                     /locus_tag="ACG8ZV_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4995999.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(53868..54737)
                     /locus_tag="ACG8ZV_000631"
     CDS             complement(53868..54737)
                     /locus_tag="ACG8ZV_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4996000.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(54807..56090)
                     /locus_tag="ACG8ZV_000632"
     CDS             complement(54807..56090)
                     /locus_tag="ACG8ZV_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFS4996001.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(56104..57789)
                     /locus_tag="ACG8ZV_000633"
     CDS             complement(56104..57789)
                     /locus_tag="ACG8ZV_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HFS4996002.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            58064..59089
                     /locus_tag="ACG8ZV_000634"
     CDS             58064..59089
                     /locus_tag="ACG8ZV_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFS4996003.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(59684..63337)
                     /gene="rpoC"
                     /locus_tag="ACG8ZV_000635"
     CDS             complement(59684..63337)
                     /gene="rpoC"
                     /locus_tag="ACG8ZV_000635"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HFS4996004.1"
                     /translation="MIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYRTLKPERE
                     GLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVS
                     HIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTEREYREKRE
                     QYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLDILEAFRA
                     SGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNA
                     PGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKNAKRKIER
                     QEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVCEAYNADF
                     DGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTMEEEG
                     REGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMITTVGKII
                     FNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKKKNLGNII
                     AEVFKRFKVKETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIENAHKQVET
                     ITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSGARGNISN
                     FTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTRKEVRHPE
                     TNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNLATGSDVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNPKGQAVIT
                     EVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGAPLTEGSI
                     DPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRVMDPGDTD
                     ILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAASFQETTRV
                     LTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVYSISDIEA
                     QMAAEDAMNNQTK"
     gene            complement(63416..67033)
                     /gene="rpoB"
                     /locus_tag="ACG8ZV_000636"
     CDS             complement(63416..67033)
                     /gene="rpoB"
                     /locus_tag="ACG8ZV_000636"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFS4996005.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLFALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            67761..68729
                     /locus_tag="ACG8ZV_000637"
     CDS             67761..68729
                     /locus_tag="ACG8ZV_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFS4996006.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            68747..69652
                     /locus_tag="ACG8ZV_000638"
     CDS             68747..69652
                     /locus_tag="ACG8ZV_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4996007.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGSAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            69649..70455
                     /locus_tag="ACG8ZV_000639"
     CDS             69649..70455
                     /locus_tag="ACG8ZV_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4996008.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            70612..71580
                     /locus_tag="ACG8ZV_000640"
     CDS             70612..71580
                     /locus_tag="ACG8ZV_000640"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004077 - biotin-[acetyl-CoA-carboxylase]
                     ligase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HFS4996009.1"
                     /translation="MTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKAIKELEKA
                     GYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAKLAAAQGD
                     SVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTIIAASACVK
                     AIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLNFSVPQNH
                     FPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKSFVLGKTV
                     SFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(71897..72421)
                     /locus_tag="ACG8ZV_000641"
     CDS             complement(71897..72421)
                     /locus_tag="ACG8ZV_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HFS4996010.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            72708..>73772
                     /gene="scm"
                     /locus_tag="ACG8ZV_000642"
     CDS             72708..>73772
                     /gene="scm"
                     /locus_tag="ACG8ZV_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HFS4996011.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSS"
BASE COUNT        22420 a        14735 c        11894 g        24723 t
ORIGIN      
        1 tattttattt tcataaagaa acagatatat ttctggatcg taattttgtg ataacagatt
       61 atctattttg atttgctcga tagttttact tagattttct gtatattcaa ttaacggttc
      121 atggaataga tcttctattt ttccagtaaa aaaataatga actaaaatca gaatatctcg
      181 aatgtctcct aaagaataca aagtcaaatt ttgcaatgaa ttatagagtc gttctctatc
      241 agccattgca acattcaaat tgttcatttt tagtttaaaa aaaactttat caatattatt
      301 tgctctaaat ggaccaaata agtaatatct ggttttaaac atgtatagaa gaaacatctc
      361 attaaaatca ccagtaaaga aatggaaatc tttagttttt ttaatattat cagttagtaa
      421 ctttttataa tcataaaaaa aataagtagt tctatctgag cgatactctt ttataatact
      481 gaattcggaa ttaaaaacca cgataggtaa ctttaaacaa acatgaagag actttaataa
      541 gacttcttta tctgaaaaca cttttgtttc tctctttcct ttctacatca ttaaatagta
      601 ttttatacgt tatctaaaat actattcctc tgtcaaaata agctaactta cttcattata
      661 aaatatccac ttatcgcttt catgtatatt ccaccgtaaa aagtacattt tatcaccgag
      721 aactcatcat ttttcatcat gatgaatact atttacatat atctagttca aagacaataa
      781 ttattatgat ccgttattat ctaagcacta tacagataat aggaattttt cgtttctaaa
      841 tattccaatt tgggaatcca ataaaaattt tcgttcaaat acgtgtctat tcgaactctt
      901 ttctagttgt taattatgaa gggggaagaa ataaaaaata caatctatac acgaataaga
      961 atattatcca aaaggaggtt ttagaaaaga tttattatac gtaaaaagct caagacattt
     1021 tcttagccat aaggacatgt ttgatattta agaagatata tgaattttct tttctaagta
     1081 taaagataac tatccattat caactaaaaa aacatttttg aaaataaaca tcagcagtcc
     1141 tatcaatgca tgtgagctta tagaagttat tcgcagcgca gcataattgc attagcttct
     1201 tttcgtgttt tttgcctctt ttccctttaa atcttaatgg aggaggtgtg caatatgtca
     1261 gataacgacg aacgcgtaaa tgcccagttg attcgattct ttgaaaaggt cattttgaac
     1321 accgctaata cttattataa aaaacaagaa gaaattcaaa aacatgaaca acttgatcaa
     1381 ctcccaccat atttgtttac taaagatact ataaaattta aacaaccgat taatgtttta
     1441 aatgtgactc tccttgttga agatataaaa ttagcaaaaa tccttccttt gttgaaagaa
     1501 cctgaacaaa tttttcttat cgaaaaattt atctttgata aaactgataa agaaattgga
     1561 aaggttctgg ggattacaag acagggtgcg acaaatttaa aacatcgact ttacaaaaaa
     1621 attcaaaaaa tgctggttta atatctgcat aataactaat tttgtatgct tctttgctcg
     1681 ttctcctcct tcccaaagaa atagattata agtccatggg aagaaggtag atttatgaat
     1741 tctttaaaag aagatttcat tttagcaaag gctggaaatg aagaagctgt tgaggcaatt
     1801 ctcaaaagat ttagctcttt gattcataag caatcctgga gaactggaaa atatgatcaa
     1861 gattgttatc aagaatgtat gcttgcaata tatctagcta tctcgaaatt cgaaattaaa
     1921 gaataactca actaagggag tctgtgacat aagtaaaaag atagtttcaa atttcgaaca
     1981 ataaatttga aactatcttc tttataatta taaagtatcg attttacagc gttctataat
     2041 gattcataga atctaaaacg aatgatttta attatcaacg ttttttaatt cgtttttagc
     2101 ttaaaaataa cttttgtcac agtctcactc ctaaaattac tttatttacg tatgaagtgg
     2161 gcaggaggtc gaatccagaa ctgggctatg gtacttcaac gaggacttct cctctagaat
     2221 tgaaaagcat gcgatttacc ttccgtaacg acggtagatt tattcaacta tgtgtccaat
     2281 caaaatttgt ctgatttcaa aaatagtcaa gagaattttg gttgttaaaa actcttatct
     2341 atcaacttcc acagtttagt tgacaaaccc tgatactaag ttgggctatg atacactttt
     2401 cttgactatc agttacgtta ccggaaggaa tgaactctat tgagaaaaac atatgatcgt
     2461 aaatttaaac taaagatttc acaggatatc cttgagaaaa aagtaactac caagaaaatt
     2521 gctgaagaat acaatatctc tcgtccaaca atttcccgat gggtttcaga atatcgtcga
     2581 tacgggaaaa atgcttttgc tggacaagga aaaagattac ctgataaagc agatttctac
     2641 attcttgaac aggaaaataa acgactaaaa gaggaagacg agtgttctac gaacacaaag
     2701 atcgatacgg atctccaggg atcactcaaa aactttacga tgaaggaatc gaaatcaata
     2761 aacgtgttgt agctgttctt atgcgtgaaa tgaatttatg cacaagagga tttcatcgac
     2821 gcaaatcttc tcatggtaga gaaaaaacaa tcaaagaaat ggtaaaaaaa tgttgaatcg
     2881 ataatttgaa cagaaccaaa ttgatgctgt ttgggtgatg gatattactt acattccatg
     2941 taatgacggt cgcctctatt tgtccaccta tattgactta gcaactcgta ttctacgtta
     3001 ctatatggta gattcacaca tgaaaaaaga gattgtcgtc cgtccattac aaatttatta
     3061 aggagaattg cctacggtaa ttcattccga tagaggtagc cagcatcggt cttttattta
     3121 tcaagagctg ttgaacgacc accacatcac acattcagtg agccaaactg ggactcctgt
     3181 tgacaatgca gtaattgaag cgtttcatcg atcaatcaaa tgagaattaa tcgactccaa
     3241 caaatataaa agtaaaatag agatgaaggt gttaatccaa gattatttag aagactacta
     3301 cccaaacaaa agaatccata caaaatttat gatgactcct tgacaatttg aagcgaagaa
     3361 aataagggat ctataatatc tagtgttggt gacgccttct gttgccaata ctttttcttt
     3421 tttctaataa acgcaaacag acaccttaaa atcctttaga ataaagtcga cgaaaaccat
     3481 tcaaaggagt gtttcaagat gtcctattca gagtttacca aagagttact agatattcta
     3541 gacctaaatc ttatctttca tgaagatgcc tttcgcaaag agcgaatcaa tgacgaaaca
     3601 tgttttgttt ttgatggcac attgacctat caaccggagg aatgctttca tcgccactat
     3661 caaaatgaac aaacgatcat taaatagggc tggaaaaaag tatccatctt attgaatgat
     3721 gtcagtaact acaagaccat tctgcggatt aacaaacagc gcttcaaatg taaacactgt
     3781 ggaaagactt ttttagcaga agattcagtt agtgatcgtc gctgctccat tgctcgcaga
     3841 gtcaaacaag ccattcttga gctattaagc gaacctcttt ctatgtcttt gatcgcacgt
     3901 atgaagcaca tttctccgac cactgtcatt cgaatacttc gcagccttcg gcctaaaacc
     3961 atttctttga gccagctgtt accagaagtg gtgtgtttcg atgaattcaa atcagtgaaa
     4021 aatgtctcgg gagccatgag ctttgtcatg atggacggca agacccatca actgattgat
     4081 attgtggaaa atcggcaact caatccttta cgcgactatt tcttgcgcta ccctataaaa
     4141 gtccgtgaac aagtgcgtct agtggtttca gatttctata caccctatcg cacattggtg
     4201 aaagagtgtt ttccgaatgc ccgaatcgtc gccgatcgct ttcatattag ccaacacatt
     4261 ggtcgggctt ttaccaacca ccgaattcaa gtaatgaaga cctttaaaaa aggggatcgt
     4321 cggtcgaagc acttaaagaa atactggaaa ctacttcaaa agaatgcgtg ggaattgaaa
     4381 ggtcagcatc gctactggcg tccgtcattt cgagatcatc tgacagaagc agagatagtc
     4441 gatcggctat tatcttatga tgattcctta aagcgaggct acgaagtcta ccaggatttt
     4501 ctttccgtta tcagaagaca agatgttcct gaattcgtcg cgctcctaaa agaagactac
     4561 aaggagttgc cagagcacta ccaaccagtg ttcacgacct tcaagaaata ccaaacagaa
     4621 atcaaacgag cgttgcgcgt tccctattcc aacggcccta tagaatgttt gaataaccat
     4681 atcaaagtac taaaacgaat tgcctatggc tatagaaact ttcaaaacta ccgagaacga
     4741 atctttttat atcgaggaaa atattttaag aaaactaaga atactaccca actgactaaa
     4801 gccagaacaa caacacggct agacaagata gctgtctagc cgtgtgagta tctcgattat
     4861 tctattgaat ttcttcacca acactcattg acgaagagcc aaaataagta atctaaccga
     4921 ctgttaacta aaccattgca ggtcccgtta aagatacttg tgcctgttgt caccgcttct
     4981 ttttcttgtc cacaagcgct taacacactt aataaagccc ctgctattat taataataat
     5041 atctttttct tattaaaaac ctcctcatct atttccagat tagtaaatgt agtaatctgt
     5101 gctttctttt ttctcaatac taataactaa cttatggggt aaacaaatac tcgtttgacc
     5161 gggttttgag atccatccag ttctaaccgc gatttgatca ggactattat cttctttaac
     5221 tcgaattctt ccatctttaa tctcaacaat attatattgt cccttcgcag gatgataatt
     5281 cacgagttta tgattgatct tatccaaatc gaagcgatcc atttccttgc catcaattcg
     5341 aacgatggca tatttgatag catcttcagt tgtttcattc tccttttcta tagagaatac
     5401 aaataaggga ataaaagagg taataatcaa aatgccaata attatgacat cgcctatctt
     5461 gacaccagct tttcttaaaa atttcattaa cgatatctgg ctaaacatat tagacttttt
     5521 ccatggaaat ggtgaaattt ttcggaaatt atctgcatta agagaatcag ttaaacaacc
     5581 ctcaagttgt tccttaatac attgttgatc catcttcata ccaataaaaa ctagtttatt
     5641 aatgcgttca ccaaacaacg gatgccaggc ttccttcaat tcgggatttt tttgtataat
     5701 catttgacac tcaattttag gtaaactagc tacccaataa tttaatgatt caatactttt
     5761 atagctaccc gatgtttcaa agatcgtcga aaaatcacta tgttgggcaa accaaagaaa
     5821 cccttttgct cttgtaatat tgccaggaaa atttttatcc gtaagatggg caaatttttg
     5881 tgcgtcaagg agtaaccgat ttcgatagat aaaacttgag ataccatatt cttctgtttc
     5941 aggaatatga ttttgatagc caagctctaa ctctttgaac cagcccactg aataggaagt
     6001 ctcatctata ttaaaaagat ttgtatttag aattttcgat aagtctactt cacctttaat
     6061 tgtcctaatt attttggcat tggactgtaa cttagcaatt agaccgttaa ttttgtaaat
     6121 cgtcttggtt gacactaagt cactattatt taaaagtaat atgttacaac actcgaattg
     6181 atcaattaac aagccacgaa tatcctgttc ttcttcaact acattacctt cagcttttct
     6241 ttcctgaatc ttttcacccg tttcgaaatt atcccaaaaa cgttttacat ccactactat
     6301 aataatggca ccaatctcta atcgttgggt caaatcaatg tctaaagggt ttttagctaa
     6361 tataattgct tgaataattg gaattggttt gctgattcct gaagcttcaa taacaatttg
     6421 attcaagtca gaaaattgca ctaattgatc tagttcaaca atcaaatctt cgcgtaatgt
     6481 acaacaaatg catccattcg gcatcgaaac aagtttttct ccagttcttt taaaaccttt
     6541 cttgtcgact aataccccat caacatttac ttcccctatg tcatttacaa tgacagcaat
     6601 ttcctttccg tgatcaccgt acagaatatg atttagaagt atcgtttttc ctgaaccaag
     6661 atagccagtt aagattgtaa taggtatttt tttcataggg aacctctttc tataccttga
     6721 atttacactt taagtgcaac acataaaaat gagtcataat cgatatccaa ctagtataag
     6781 tttgtcgaga acactcctag aaggaaaata attatgagcc agtatcgtca tcttactata
     6841 ctcgaacgag aaagaatctt tctgcttcac gaagaaggat tttctattag tataattggc
     6901 aacgacattc agcatagccc gtttactatt ttacatgaac tgagaagaaa caagaaaaaa
     6961 actattcacc ttccaaagcg gaaaaaaatt atgcttatcg aagaaaaaaa tgcggacgtt
     7021 atcacattct aaatgatccg tgagtttggt caattgttcg tcatttattt gtcgattttc
     7081 agtggtcgcc agaggaaatc tcgaatcgtt tgaagcatga acatatggac ttttcaatta
     7141 gttttatcac gatctaacgt gcaatttgca atgatctttt cgatacagaa cccctctcac
     7201 acggcaataa aggcctgatc cgttcattgc accatcgagg aaaaacaaga catacaaaaa
     7261 atcatgtcga gtctcgtgga aagatttgcc ttactcattc gatccatggc cgtccaaaat
     7321 ccgcagatga tagaagtgat tttggtcatt ggaaagccga tattgtagct ggcaaaactg
     7381 gtggtacttg tttagtgact ttgacagaca gaaaatcatg cttcctttta gcaggaaaga
     7441 aggtccccag aaagaaagcc gcttatgtga gcgagaaaat gattgaactt ttaagcagta
     7501 ttccaaatga ggcggtcaaa acgatcactc cagatagagg aaaagaattc tccaatcatt
     7561 tcgcagttac agaagcattg aataatatgc ccttttattt tccagatcct catgcccttg
     7621 gcaacaatga acaaattaaa atacgaatag actcattcga gaatacttgc caaaatcgaa
     7681 agagatagct acggtagata actcaacgat aaatcagatg attgaaaaac tgaataacag
     7741 acctagaaag tgtttagatt ggagaacacc ttatgaagtc ttctttgata aagtgttgcg
     7801 cttgatttga caattcaaga cataataaaa agcagatcaa atccaaataa gggaaaaatg
     7861 atctactctg gtattatcaa ttaattggcc aagctattat gccgttttgc taaacgtcta
     7921 cttcttccag tattgacctt gataaaacaa caatcaggat cccgttttaa tactctatga
     7981 actgtgtcaa tactaacatg taaagttgca gcaatatcag ctaatgtact cccatttaat
     8041 ctcatttgct ttgcaaatcg ataacgccga taagcatcaa tattcttgga atccatagac
     8101 aataatactt ttcttaccat gtatttcctc caaaaattga attttaatga gccatcattt
     8161 cttgagcaat ttcatgttta gacaatgaag ctggatagaa agtaggccaa ttatgcaatt
     8221 cattatagag tttttcttga ctttctccac caaagaaaat atggaaatgc tctgccttac
     8281 ttggtgcaat tccatgatca ctaaattgaa tatatttaaa acgaccagca cctgcatcat
     8341 cagtttcaaa attaaaacga acaccacggt ttcctttttc ataattcaaa attttgtatc
     8401 caacatattt gtatgtgtat tgatgatgtt caccgttgac tacaaaatca atggtgttgt
     8461 ctttaatgtt gatagtatca atatctgtct tatagccagt agtataataa tctttgtact
     8521 cggcagctgt catgtcttta ttgatttttg ctttgtaatc gaaaacttca tccaaaattc
     8581 catcttttaa caacggataa acagattgcc attcgcctgt ataatcactc aattcgcgat
     8641 ccttcacatc ggcatcttta aagtacccat tagcaactgt cttttcatcc ttcgcttctt
     8701 tttctggaac tacctcttca ccagcaacca tagttgtttt ttctaacgct tttagattgt
     8761 cttccattac tgaaacataa tcttcaccat tatccatttg ttcttttgta agactttcaa
     8821 gaggattcag tacttccaat tttatcccag cttcgttggc caaagttttt gcaattttat
     8881 cattagcatt cttttcaaag taaatataat tgatcttatt ttttttaaca tactctttta
     8941 attcagctaa tcgaccagaa gatggctctt cttcaggact tagtccagca ataggaactt
     9001 gtttcaatcc ataatccaaa gctaaatatc caaaggctgc gtgttgcgtc acaaaacttt
     9061 tttgtttcgc ttctttaaga ctagtggtat agtcagcatc caaccgtttc agtttagtca
     9121 aatacttttc agcatttgtc tcaaatactt ttgctttttt cggatacaat ttaactaact
     9181 gatccttgat atttgaaact tccttaattg ccattttggg tgaaacccac gtatgaggat
     9241 ctagttcatg atggtgatct tcttctccgt gatcatgatc ttcttcttca ctacctggca
     9301 ataaaatcat gtcttttgtt ccttctacta cattaggccc agctttcttc caactttctt
     9361 tagcttttgg tacccatgat tccatgtttt cgttatgata tacaaaaaca tcagcatcat
     9421 gagcttttgc catatcctta gctgagggct catagtcatg aggttctgat cccgctggaa
     9481 ccattaaatc cacgttcgct tcatcgccga cgatgttttt ggtgaaatca tacattggat
     9541 agaatgttgt tacaatttct aattttccat ctttatcatt cgatactttt gcatcattag
     9601 tgctggagca agctcccaat aatcctagag ctgctatccc aataagtcct acactgattt
     9661 tcttcattct ttttccttcc ttaattatgc taatttcttc attttatttc gtttatgttc
     9721 tttgataatt tttaatgccc tttttctagt tttaatattc gggcttttaa gtcgtcgata
     9781 tgcactagat atatccgttt tctccattag aaattacccc caatcactac ttatcattat
     9841 ttgctttccg ccagtaattt atcaaaactc tgtttgatcc tttcttcatc caacattttt
     9901 ccgattagaa taatagtggt ttggtctttt tgtcgagtgg tgtattgaaa attaacctgt
     9961 tcgtttacct cttgcatggc aactataaaa tcctgctctt gtaaagcaat caatccttta
    10021 aaacgataca ggctcccttg gttggttaaa atcagccagt caatccattg gagtaaaaaa
    10081 tcttttttta tgtcttgatc tgaagttaag agaattgatt taaactcatg tacttgatgg
    10141 tgttgatgat agtatttgcc attatagtga ttttctgatg aatcactttc aaaaactaag
    10201 ggatgattaa attttttcaa attataaaaa tccttttttt gaatcgtttc actatgtgtg
    10261 aacattcgaa tatcggataa agggttaata cttttgattt ctctctgtaa tttttttagt
    10321 gcagataaat tcaagttttg ttttctagac acaaaaatgc gatctgccat gacaagttgc
    10381 ttaagggctt gtggttctct ttcaataagt tcaaaactgt cactatcaat aacagtcaat
    10441 aaactatcga tatatactct tcctcttagt tgaggcgctg ttaaaagtgt ttgaatgatt
    10501 ggttggggat ctgctatacc tgtagtttca atgatgattt gtgaaattgg ttgttgatgt
    10561 tcttctattg tttccagtaa agaaatcaat attgctaata aatcactgcg aagactgcaa
    10621 cacatacatc cattatttag ttgtaacacc cgttcctcgc tatgaactaa taatttgtga
    10681 tcaatcccaa cttcaccaaa ctcattttca attataataa tttcttccct ggggtagggt
    10741 gagacttgca aggcttgatt gattagcgtt gtttttccag cccctaaaaa cccagaaacg
    10801 attgtaactg gtatgcccat tttgtcacct ttttaccact tagctatttc acttctttaa
    10861 aaattgcccg tctgcgcaat tttggcgaat acttttttaa ttctaaccgt tcagggttat
    10921 tccgtttatt tttgctggtg agatacagac gttctccagt ttcgacacat tccaaaataa
    10981 tattttgacg cataaatctt cctccttcaa tacttatcga tcttcaagat atgcttgaat
    11041 ttgttgtgca tcttcaaaag ttaactcgcc agattccaat tgtgaaacta aattttcttt
    11101 catatcaaca ggtatctccc aataaccatc gatacattga aataactcct cgtcatactc
    11161 ttcaaaaatt ggatagattc ttaaaaaatc atcaaatgat aagccttggt cctcatagta
    11221 atctttgact aatccatttt caattgcctg ttgggtcggt aaacccgttt cagtaataat
    11281 tcctctctct accatcgaac gataaaaagt gcatttatct agcgattgct gggtcgtttc
    11341 aagataatac tttaatcctt cttcaactaa aggtgggtaa ataatttcca ttttgattcc
    11401 ctcctaaaag ttatatatta aactattttg aagctccttt aattactttc tttccattat
    11461 agtacccttt taaagataca tgatggctac gtctataatc accattcgct tcgtcaaatg
    11521 aaatttctgg ttttactaca gtttgatgag ttcttcttaa ccgtttcttc gccttagatg
    11581 tttttcttgc tggtactgcc atgatatttc ctccttttac caacttgctt tttttactcc
    11641 aggaatcaac ccttgatggg caagttctct aaacttaata cgggacatac cgaactttcg
    11701 catataccct cttggacgac catccgtctg atcacgaagc ctcagacgat tcggatttga
    11761 atctcttggc aatttagcga gagcggtgcg atctcctgcg gcttttaatt cctgacgttt
    11821 atctgcatac ttttcaatca tcgccatttg tttctttgct ttagcaattt tcgacttttt
    11881 tgccatatac ctttatactc cttttatttt gatttagaca cctcaaatcg taatcgttac
    11941 gttttgacac tgatacttta ccaacaagag ttgctcttgt caacaataaa taacatgaaa
    12001 taaaactcat atgaatagat aactatttga aaacgaattt atcggtacat agagataatc
    12061 aaatcattta aaagaatatg cagtttaggc tctgaaaaat aagaattcac ttttattagt
    12121 ccaatcaaac acaaataccg ttttaagtag cttttcctct acttaaaacg gcaatatgaa
    12181 agaaactata actttttatt caatctttta tgtttaactg gtttatcgcc aattttttaa
    12241 aactttgatt attccttata ttataagaat agacattaag tgaactaatt caatcatact
    12301 gattctttcg tgtattcaaa attagatgct gtttaataaa attattcttt ttgaaaaaga
    12361 attataacta tatcccaaaa attgtaggtt aatttaaagc ctatttcatc atcgtgattg
    12421 agcttctttt tcatagacga atttctcaga tagtttagtt ttctttatga gatttttgta
    12481 tatttctgac cttcgataca actcattatg agtaccttga tcaactagtt ttccttgatc
    12541 catcactaca attttattta ccttttcaat agacttcaag cgatgcgata taattagtac
    12601 tgtcttatct tgtattaaac gatttaaact ttcctgaata cgtttttcat tttccgcatc
    12661 taaactggca gtaatttcat ctaaaattaa aattggcgca tttttcaaaa aagcccgtgc
    12721 tatggatagg cgttgtcgct ctcctccaga aagtgaactt ccgttttctc cgaccaatgt
    12781 atgataaccg tcaggtagtt tttcaataaa gtcttcgcag ttagctaaac gagctgcttt
    12841 tttcacttcc tcatctgacg cttgactatt tccaatacgt atattttcca aaatacttgt
    12901 attaaacaaa gttacctctt gaaaaacaat agcgattttg ctaaacaaag aagctggaga
    12961 tacacgttta atatcatacc catcaattaa aatacagcct tcatcataat catacagtct
    13021 agacactaat ttcaagatac tagttttccc ggaaccacta gcacctacta acgcagtcac
    13081 ttctccttgt ttagccgtaa aagagatatg atctaaaatt ggggtattgt tatcatatga
    13141 gaaagagaca tctcgcaact caatgtcaaa agatttcaga ggactatctg atccctcttg
    13201 gatactggtt tccttcatag ctctaattcg ctgtatttta ggagctaaat aaaatatttc
    13261 aagcactgct tctttcatag aatcgaagga atcctttatt tttattgcgg ctagtaagta
    13321 accaacgacg tagagtatag tcacttcacc cgttaacagt aagtgaacac ctactagaat
    13381 gactactgct aaactaacat atgagaaaat agaggataag gccatgactg aaaaagtact
    13441 taattctacc tttaaatgaa tcctttcact ctcttccatt tttttgaaaa gtctgtcttg
    13501 aactttttta gatagattaa agctattaat ctcttgctgc aattctatag tttcttgaaa
    13561 ttcttccgag ttttctctca aagtatcgta atatttagta ttggctttcg tttgggattt
    13621 ctttgataac aagattaaga caaaactaaa taacgttggc aaaataacag ctaatcccat
    13681 tttgacatta ccaaccaaaa gcatcactga aataaaaggg aaaaacagag ccataccgcc
    13741 ggctttaggt attgcatgac tcatcgcatg ctcaatacct tcaacgtcag acatgatagt
    13801 ttgagataaa tctgataaat tatgttttga aaaataggat aatggtaaat ttgacaaatc
    13861 gtctgcaatt tgcactctta aatgcgcact ttctttataa gtactattat ataagttttc
    13921 atactcccta tctaacaacc aatacatgaa aagcaaagta acaaacgata cggcaaaata
    13981 aagccaacgg ggctttgtat tttctaaaac taattcgtct atcagcatca ttataatgaa
    14041 tgctggtacc atattaatgc agtatacaaa aaaactagaa atagaagctt tagttaaagc
    14101 ttctgcgccc tgatcactta aagcaaattt gtttttataa aaacttttca ttgtcaagcc
    14161 tccaatcatt tgcattctca taattagtga ccaattgttt atacacttga tgtttagcca
    14221 ttaattcatt atgatttcca cgttctacta ttttcccttc tgacaagaca agaatttcat
    14281 ctacagattt aatgctggat aatcgatgag ctatcataat aactgttttt tcttttatca
    14341 gatgttgaaa agccttttgt agttcatact cattatctgg atcaatagat gcactggctt
    14401 catccataat aacaatcttt gcatctttta aaattgctct ggcaatagct atacgttgtt
    14461 tttctcctcc tgacagataa actcctttac taccaattaa ggtatgctct ctttcgggaa
    14521 atttttctaa aatcgattcg caaccggcta atcttagcgc gtcaaatact ttacttgctg
    14581 gcgcttgagg atttgctata gaaacgttat cgtaaatact ctgattgaat agtttcgtat
    14641 cttgaaagac aaaagcaatt gtgttaataa ttgtgtcttt tgaatagtga tttaaaggct
    14701 taccaccaat tttaatctgt cccttatcca cattgtagaa acctgaaatt agtttagcta
    14761 tcgtactctt tccgcttcct gattttccta ctaatgcata aattcttttt tgttctaaaa
    14821 ctaagttgaa attttctaaa acacactctt ctttgtatga aaagctgaca ttttcaaatg
    14881 caatgtcaca atttttaatc tgtgtctcgt tcccatattt tagttggtct tgcttcattt
    14941 ctaaataaag ggagtctagt gtttcgactg catatcttgc ttcaaacaag tgcatactta
    15001 catacattat tctcatgaaa gaaacaaaaa taattccact taaaaaaaac aacatcaaca
    15061 agtcaacagc taatatcttg ggagtggtaa gagaagttat aaaaaaggtt ataggaacta
    15121 tcaaaatgca aactatgcca aaaaatagcc attgaaaaag aacaaaaggt gttttcccac
    15181 tcaaagaata cttatatgca aacttagcat aatcgttaat tgctttattc aaggctttaa
    15241 atgatgttac tttagcacca aatatcttta taacttgaat tccgcggata tattctaccg
    15301 tttcagagct taacacatct aacgattctt gatatttttg aataaaattt gtattctctg
    15361 tcattttctt taacaagaat acaccaatta ctaacatggc gattagaacc aatccaattt
    15421 taaagttaat gaaaaagcct aaggcaactg ataaaacagg tgttactatg gcttgagcac
    15481 tatctggaat caagtgagca attgccatat gtgttttagc cgcgttgtca tcaattgtct
    15541 ttcgaatata tcccgaagaa tttaaatcaa aaaaacgaaa acttgcttct gttaaaccgc
    15601 taattccctt ttttctcaaa ttagtctcta agcgaaaccc aaggatatga gaaaataagc
    15661 cagaaaaaat ataaaataaa gctcctaaag ttaaccaagc aacagtttga accgcataac
    15721 tcttagctaa atattcatct cctacaataa ttagagactg aagaaatttg taaatactgt
    15781 aatatccata gactgttaat acgacagaaa aatcagaaaa taaagtggct aaccatccgt
    15841 agtatttcat tttagggaca taactaaata attttttgta tactttcatt ttttcctccc
    15901 ccgcattcaa tttcttctct tattcgttta caactgttaa tgctttccgt aatagcgtaa
    15961 attagagatg tacaaacaga taaaaggtaa actacgttct attttttgta tttttttaag
    16021 acttttcttc caatcaatac accaatcata gataaacttg ctacaactaa cactgaaatg
    16081 attccccata tacctaccgc atagtggatc attgcatcca ttgttgcagc agattgtcct
    16141 ttatctatcc aatcttgacg aaaacgatct gtaaagaacc atataggaat ccactgtccg
    16201 gcagcactgc ctaattgcat tagagcccaa gacgcaactt gaggaattgc tcgatcatat
    16261 ccaaatacag atagaataat atcagctaag atcgccatac taatcgaact gataaaccaa
    16321 ggtaagtacg ccccgcccat taacgtaaaa aataacaata aaacaattgt gtaaatagta
    16381 aaaattcctt ttctagggta gttatagcta atataaacaa atatgattcc agataataat
    16441 ccaaaaatcc cgggggatat gctgtgacca aacgccccac caatactact aaccattatt
    16501 gaaaaaaagt aaattactag ggaaataact gtagctaaac caataaaaat ataatctttt
    16561 gttttcatat atattctcct caattctatt tcgttatgtc attaaaaatc tgttctatca
    16621 aagttgaatc ttctactcta agttttatat ctttttttat tccaccattt tttaaataaa
    16681 taattctatt gcatgtttta taaagaaatt ccggatcatg agtagctata actactgcac
    16741 ccttttcttt taagtcttta ataaggtcag caatcctttc catattaata taatccaacc
    16801 cacttgtagg ttcatcaaat agaaataaat tagtttttga caatgaagct atagaaacca
    16861 ataatctttg tttttctcca ccggataaat caaacggtaa ttgatctttc attttataaa
    16921 gttccatttt ttttaaaatt ttttcttgct gatctttact aactatttca ttccccaggg
    16981 ctaactcgct cctcactgat tctgtgaaaa attggtaatc catttcttgc attactaaaa
    17041 acggcgatga caaatttttt ttattttcga ttatctttcc tttggtaggg cgaataatct
    17101 tcatgagtat tcttagtaag gttgttttcc ccacaccgtt tttccctacc aaaccaataa
    17161 catctccaac tttgacatca aaatttatgt cttttagaat attttcataa gtaatttctt
    17221 caacttttaa tacatctgca cttacctttt cgatataggg aacttcaatc gaactattaa
    17281 aaatgtcaaa tttccttaat gcgttattgt tttcagtttt taacaactga atagttgtag
    17341 tttttacagt tctattttta acaaatagaa cttgatcaat taattctttc aaatagtaaa
    17401 aacgatgttc agctataaca atagtaaatc ctttattttt taaatcacaa agtaagtcag
    17461 caagtttctt agtcgctttg aagtccaaat ttgaagacgg ttcatccaat ataattaatt
    17521 tagagtttag cgataaacta catccaatag aaattttctg ccgttcacca cttgatagcg
    17581 aaaaaatgtt tttatctaat atatttgaaa gatctaataa ttcagctaat tcattgattc
    17641 ttttatccat atgctctttt gtaaatccaa agttttccat cgaaaatact aactcactcg
    17701 ttgtatttgt tgtaaagaat tgtcctctag gatcttgact tacgtagcca atattttttg
    17761 atatactttc ttgtgttaag gattgtagcg agttattttc aaataaaatt tccccaacca
    17821 attttccgtc ataaagtctt ggaataagtc cattcattaa ctttaatagt gtggatttcc
    17881 cactcccaga agaaccagta atcaatgtaa gactgccttt ttttattgaa aaattaaggt
    17941 caacaagcgc ttgttcctta acatccttat atgaaaaaga aacattgtta aattcaaaca
    18001 attctttcac ctcaaatcaa aatacttaag aaaaaaatag taacggaaaa caggatgata
    18061 tagtctaata agctcatgtt tgttttatag taagaacttc ttttcacagg agattctatc
    18121 ccctttgtta ttgcattagc ggtcatttct tcagcaatca tagttgcacg tataagaacg
    18181 ggaactaaca gaaattccaa atattgcaga ggctgaaaaa aagacaagcg aatgtttctc
    18241 atttttaaag attctttaat cattcttatt tcagaacgat aagtcggaaa gaatctgatc
    18301 actactgtaa tacttaacat tatttttttc ggtaaatgta ttttttctaa agaggataat
    18361 aattcattgc tagtatagac actaaccaac aaccatgaga tcattacgac cggcaacatt
    18421 cgaaatacaa tatataagga tgtcgcaaaa aatatagtaa aaaactctat cttgatagca
    18481 tcaataattt tcattactaa aaacagaact gaataaatca agatgaaata aatacatgtc
    18541 tttattttac gaaacatcaa tactaaaact gtagcaataa tgaaacaccc cacttgaaat
    18601 atatttccct ttcctaaaaa aataatgacc ggaaaaaaaa tatttaaagt aatcaaggtt
    18661 aacggattga tttttgacac tctttcacct ccaaaaaata agatcgcact gttatcttaa
    18721 gctgataaaa atgcaccgtt attcagataa cagtgcgatc ttatcaaaaa gcataactga
    18781 gaacaattct caatgcaagc tttttttaat taactcagta attcaatcca cccaggaaca
    18841 gaaaattgat acaatcttct ggttaatagc atagtctttt cttttgaata gctatgcttc
    18901 aatatatcat agaatgtagc gtagaatgag taaatgtaga agtggatttc ttcttcatta
    18961 aagactaaat tttgattgat cattccgata gtctttaact tatctagaca acagactgtc
    19021 tttttcgtca caaatgatgt aattttttca acaatatctt gatatttggt tccagctgat
    19081 tggaataaaa tcaaatcgaa tatacgttta ttctcaaaaa tataattaat aaatggatct
    19141 aattcattga agttctctct ccaacttttc tctatatcta tattttctaa gtttaagagg
    19201 tatttggtaa actcttcatt atacatatta ataagcgcat taatatgcgg ctgaataatt
    19261 tcttcaaata acgcttcctt agaagtaaaa tgtttataaa aagcacccgt agttacgcct
    19321 gcggtcaggc acagttgcct tatcttagtt tgctgaaatc cttctttttc aaaatggctt
    19381 agtccacttt ctattaactt ttggtgagtt ataatataat ctctggtttc tatgggtact
    19441 tcctcctaat aagatgaatt aactttatta tcttacacag gacttgaagt ttcaatcgtt
    19501 aacgtttatt actgaactca ttccttagag ctaaactaat gagaaagagc agaataactg
    19561 atacaaaaag caatcctaca agaattaata gactcatcta aatcattcac cttttctaaa
    19621 ataatccgag aaagatttaa aaaaattata tccagctatt aggataagtc ctatcataat
    19681 cactccaata gccattttct tatcctccct aaaaataaag tcttttactt aaaacctttt
    19741 ttgtaatcgt caataaattt tttcccttta tcagttaatt gaaatcctat atctaaatag
    19801 tcctcatatc taagtttagc cagcatctca cttacagatg ctggactaac acttagaact
    19861 tttgctaaat cattattttt taatttcttt tttctttttg ataattcctg aattgctagt
    19921 aaataaatta gtatagtagt cgttttaatt tgtaccatac ctaccctcca aattatttcg
    19981 aaaggccttc agcaatttta tccaggttcc atttcatcat cgcatagtaa ctatcaccat
    20041 cttgtccttt ttctgcaatt gaatcagtaa aaatcgttga atagatagga atattggtat
    20101 cttttgatac tgttttcatt ggtctatcat ccacactgct ttctacgaat aaggagggaa
    20161 cttttgttgt gcgtaatttt tcaactaagt gttttatttg atctggtgtt ccttcttctt
    20221 cagtgttgat ttcccaaatg taagcagaag gcacattata cgctttcgag aaatatttaa
    20281 agcatccttc acttgtaaca atcatttttt tatcattcgg aattgaagca aatttagatt
    20341 tagcttcttt gtctagagaa tccaattttt caatatactt atctagattt tctttataga
    20401 attttttatt atcaggatct ttttccgcta actgtttttc aatattttta gcgtaaataa
    20461 taccgttttc taaatttaac caagcatgag gatcttcctt ccctttctca ctctgaccct
    20521 ctaagtaaat aacatctatg ccatcacttg ctgcaaaata gtctttgttt tcctctttgt
    20581 tcgcattttt aactaatttt gtaaaccaag catttcctcc agtttccaag ttaacaccgt
    20641 tataaaaaat caaatctgct tttgaagttt tttgaacatc ttcaggcaaa ggttcatatt
    20701 cgtggggatc tttcccaata ggtacgatac tgtgtaaatc aattttatct tttgctatat
    20761 tttcggtaat atctgctaaa atcgaattag taactactac ttttaatttt tcgttcgaag
    20821 ccactttatc tttgtcttta ctatttattg aacatgcccc gaatataaaa agagcaatca
    20881 aaatccccag acttcccagt actgctttcc attttctcat cataacgatc tctccttctt
    20941 tcttaaaaat ttttgttttg gtgagattag aaaactaatt acaaataaga atgccgctgt
    21001 taaaacaata cttgatcctg ctgctatgtt aaaactataa ccaataaaca atccaagcaa
    21061 tgatgaactt gctccgactg ttgcagaaat aaatatcata gttttcaagc tatttgcata
    21121 taaatatgct gtagctgctg gtgtaattaa cattgcaaca attaatatag ttcccacact
    21181 ttgcatagct gttactgcta ctaaagttaa tagaaccatc aatagataat gataaaaact
    21241 gacattcatc cctattgctt ttgccattaa tggatcaaaa gaagtgatta ataattcttt
    21301 aaaaaataga actactataa ccaacactaa aaccgaaacg ccaattgtaa tccacttatc
    21361 aatatcttgt acagctaaaa tatttccaaa taaaatatga aataaatccg ttgagctatt
    21421 tgcaactcct ataaggataa ctcctagtgc taaaaaagaa ctgaaagtaa taccaattgc
    21481 tgtatctcct tttattacac tattgctttt tataaaagta ataatgatag aagctaatag
    21541 accaaataca atcgcaccaa taaaaaaatt aatacctaaa atataagaaa ttgctactcc
    21601 tggcaaaaca gcatgagaaa tagcatcacc cataagagac attcctctta aaataataaa
    21661 acaacctact gttccagaaa caatccctat aactacagat gtaattagag cattctgtaa
    21721 aaagtgaaag tcatacagac cattaataaa attttgaagc atattattcc ccctctccaa
    21781 taaatatagt atctccatag gcttttttta aattttcttc attaaataca gattctacac
    21841 ttccgtgagc aattagattt cgattcaaaa gaataatatt atcaaaatac ttctttacct
    21901 tgcttaaatc atgatgcaca attagcactg tttttccctg atgtttcaat ttttttaacg
    21961 tatccataat tattcgttca ctaactaagt ctatccctac aaatggttca tctaaaaata
    22021 tgaaatccgc attttgagca agacatcttg ctaaaagtac acgttgaaat tgtcctccag
    22081 ataattctcc tatttgatga ttagaatatt ttcccatatc gaccttttcc aaagcctttg
    22141 aaactctttg ccattctgca tttttaattc tttgaaaaac tttcattccg gcatatgttc
    22201 ccatagatac acattctttt acttttattg gaaaagtaaa atcaatatca gctttttgct
    22261 ctacatatgc aatcttcacc agttttttat tgatatcttc attattaatg gagacctctc
    22321 cctgatgagg gataatattt aacattgctt taagcaatgt ggattttcca gcaccatttg
    22381 gaccaataat acctgttaaa gcaccttctt gtatttttaa agaaatctcg ttcaatgcta
    22441 aaaaatcgtt ataacaaaca ttaagctttt tcacttctaa cataactttc tccttctaaa
    22501 tgataatgat tatcacgatc atatggtata caaaaattat attttagtca accctaaatt
    22561 ttatagttta gatttttttc tgttgctgaa gattagaatg acaaaactat ttgaaactac
    22621 gcgtatagta agtagctttc aaaatatata aaaaaggagc gttctcaaat gagaacatgc
    22681 tcctaaaact actttattgg cgtatggaaa aattatactt gaagtggata gcgggttgaa
    22741 taagttgata agcatcaaaa catttataaa aattattcaa gactatgtct gttccatata
    22801 caaatatgaa aatcagtaaa ctccatttaa cttttttcgt agtgtgtctt tttatacatg
    22861 tttatcgtta ttaatagtga ataggaaaaa aactattttt gatcattgac aattaaatac
    22921 aatttttgaa taacgatccc tgctattcga gctagaaact caagtacgcc atgacctgat
    22981 tagcgacaaa tacttagaga tttctttttg ttctgggaaa acaaaatgcc atgacaatag
    23041 cagcaaataa tgatacttcc gtaaggctcg ccgtaaactg gggagaggtg aaattcctat
    23101 gtgcttaccc aaagcaattc aaaaatttca taactactat tttaggagat gattttatag
    23161 aatccagagt ctacctgaat aaaaaacaaa cctgtgcatt tctaggaatc gataataata
    23221 ctctagataa gtggattcgt atatataatt tcccagtaat aagagttggt ggtgtagttc
    23281 gctttgacgt agaagatatt aaagacttta tgaatacatt taaaataact tgaaattttc
    23341 ttctcgccgc atatactaaa attagtgaaa tatactgcct tacttttttt aaggagtgag
    23401 gattttgcct acaaagcttt caaatgggaa atataaaact aatctgagat atccaaaaag
    23461 gtttaaagaa ataacaggaa ttgcatcaga aaagtatcaa aaaacatttc caaataggca
    23521 attggcgatt aaagccgaaa atgatatgaa gaagaaaata gaaaaagttt tgagagagga
    23581 gaatgcaaac tcattagaat taaaaggaaa aataacgttt aaaaaatttt acgaatctaa
    23641 atggcttcct agatatgaat taggtcaaac aattagatca aacaggcctc ctagtgatat
    23701 aaccattagt aatacaaaag atatatttcg gttgcatatt ttacctatgt ttggtgaata
    23761 cgcaatgaat tatctaaata tcaatactga gataatatca gatgaattaa ccaaaaaatc
    23821 gaaagaatat gcaaatataa aaatcataaa aggatatgtt cgttccatgt tcgatattgc
    23881 agaaatacta aattatatcg aatttaatcg aactactaaa attattcaaa gtatcactgc
    23941 acctaaaaaa aatgctttag aagaaaaaag aatacaagaa ggtaagcaag cactatcatc
    24001 aaaagaactt actaattgga tagaagcagt aaatgatgat tttaataatc atttacttac
    24061 ttttcatgat tacacacttt ttatgattac cctgtatctt ggtgatagaa aaagtgagac
    24121 ttacgctttg caatggaaat atattgattt tgaaaaacaa acggtccgtc ttaaacatac
    24181 tttagataaa tatcaaagaa aaaagtttac aaaaggtcga aaagataccg tcattcaagt
    24241 accagaagtt gtaatgacat tgctaagtga atggaaatcg gtacaagctg atcaattgtt
    24301 gaaattaaaa attaagcaaa cgttagatca gtatctcttt acttatacta aaccatctgg
    24361 agaagtaaat tgtcctgttc atgccgatta cctaaactat cgaatcaatt caattaaaag
    24421 aaggcatcct gacttagttc atttatctcc acacaaactc cgtcatactt atgcaactat
    24481 agctagacaa ggtggagcag atatgaatca aatttcaaat gctttaacac actcagatat
    24541 ttctacaaca aagatatatg tgaacacacc agatatagtt gataaggctg tttttgaagc
    24601 ttttcagaga ggattgaata agtgtgattg atatgtgttc ttaaatgtgt tcttaaaaac
    24661 aaaagaagca ctttccaaat aattgaaaag tgccagaaac gttgatatat aaaggatatt
    24721 aacgttttga gaattgtgaa gctttacgtg ctttcttaag acctggttaa acaaactttt
    24781 catttataat gttttacaga gatatatgtc gtatgaaatt aatgttctct tgttcatgaa
    24841 gttttacaga attgtatagg gttatctgtt gtcattacct caaatcatta ccacaacttg
    24901 gcgagttggc tgattgaaga agtactctgt tttactctat cttactctgc tttactctat
    24961 cttactctgc tttactctag cttactctgc tttactctag cttactctat cttactctat
    25021 cttactctgc tttactctat cttactctgc tttactctag cttactctgc tttactctat
    25081 cttacctgct ttactctatc ttacctgctt tactctatct tactctgctt tactctatct
    25141 tactctgctt tactctatct tactctgctt tactctatct tactctatct tactctgtct
    25201 tactctatct tactctgtct tactctatct tactctgttt tactctattt aaagaatagt
    25261 attgagtcgg atctttggta ctagtaccat gccactgaat tatttttttc cttaacattt
    25321 cctttaatac cttacggcta tatccgaccc ctttttttaa tacttctgaa gcttctttta
    25381 ccgaaatttt ttcgttatta aataaatgtg aaacaatcat cttctcagaa gtagacaaag
    25441 agtctacttc aaattctcca agataatcat ctagtctgtc tctctctctt aaatgtctag
    25501 aggttatact attttctaag actaataaaa ccgaattatt atttggctca ctatatttag
    25561 gttcatttaa aaatagtaat tgcatttcgt catatattcg attcacacct tcattaagtt
    25621 ccttaaccca tccgaattca gataatgtcc tagcgattct gggattccta gcatacctag
    25681 ttcggcgcat attttgtaaa gtgactatat taggtaaagc tcccgggcta aaaatttcta
    25741 acctatcatc atacatatta attctaacgt aatccccttt ataagaatag tctctatgcg
    25801 ttaaagcatt gactatacct tcaaaccatg caaattcagg atattcaggt atgatactaa
    25861 actttccatc atcatttaaa tactgaaatt ctcttagttg cgtttttaca tccctagtta
    25921 tagattcgat tagctttgga attgcacctt catagtcaaa ttctttaact atatttaatc
    25981 tccgtccagt ttcattacgc ttaccatcat atctcaaaaa acgaattcta gaattaggta
    26041 aggctagaaa tgtattctta ccaaatagaa gcatgccagc atttgtcaag tgaccatttc
    26101 tcattaaccc tcttccagtg agtatggttt ctgtggatat cgcttcagct ttttttaatt
    26161 ttttatatga atccatgaga gattcatcaa tatcatcaag agtactgtct aaaatttcta
    26221 tatcttcaaa cattctctgt cctttgtcgt attctagttt ggatatttgg tcatgagttt
    26281 gatgaacact tttatcccca attctcaaga aacaatcacc gttcgaatta aaaatcacat
    26341 ggcttatgct aggttcaacg tctataatga ataatatatc gtcttctcct ctagcattct
    26401 taatactctt catttctttt ttaaaagttg gattgggttt tgtcattgaa tttatagcta
    26461 gtacatattc atctggatcg atcgcacctt gaaatttaaa cccagaaata gtcccatcat
    26521 cttctatacc gattaccagc ttacctccat cggcatttgc aaacgctact atgtgtttta
    26581 taatatctct aggcttaatc cgtgcacttt ttctatcaaa atactgatct tctttttcac
    26641 ttataaactt ttgaatctca taatccattt aaaatttccc ttcttaaatt tttttattat
    26701 agagccgtat attcaatttc cacaaaaaaa taatctaaaa caaaacagac accttcattt
    26761 tgatatgttc tcccacatat gaatcggtcg ctatacagca ttacatatag taattattca
    26821 tactgcgaaa taaatagctc caaatcttta gctggcgtag ttaagcttaa attcgaaatg
    26881 aaagtttcat tgactattcc actttcatca aatcccttct tcaaccaatc agagttccac
    26941 aacgtaaatc ctttaggatt agaaactttc ttacataatt ttgcactata ggatttctct
    27001 cttgaatgaa ttaaagaaag tctttgtaac caaatttcaa ctatatccgt attaggagta
    27061 ttaacaaatt ttcttaagat tttatccaag tataagttga tttcttctac agcaataaac
    27121 tcaaaaagct tacctaaaat cacaatacaa gcctccaaag ttctaggatt cttttgcatt
    27181 atattaacaa gaatactaat caattggtag atatcatctg gtcttttgtt taaagtagaa
    27241 actctatgtg tatagacttc acttagcgct ttacttaaac tcccgcaatt tggatatttg
    27301 tctcctaaaa gctttacctg tagcaaatgc ttttgaaggc taagcttaaa cttccactta
    27361 ttattacttt tctctgtaaa acttgcatgt ttaagatccc agtaaatttt atcaggctta
    27421 attgcatcta aaattatatt atccgataag aatgttttat ttgaatttag cttcaaattt
    27481 agatccgata atacttcaga taacaatctg ataatcactt cagcttgatc ttttcgaacc
    27541 gaaaaaattc tataatcatc tctgtaacga agtattttga actctttaat ctctgttttt
    27601 tctatcttgt tcagtaacat tttatcagca tacccaagta ctatttcagc tacaaaatcc
    27661 atcaatacat ttccttgagg tataccgttc gtttgtccat tttgtaaata tcgtatttta
    27721 gaatctatta agtttccaac gccttgagta tcttttctat gtgtcttagc ccattctttt
    27781 gaatgtactg cccacgggat agtatgtgtg tacattgagc tataacaatc ggtaatatct
    27841 gaatgaatgc agtagtcata ctccaaagca taactaatct gtgcttgttc aaggttctcc
    27901 caccaattta aaatagtttc cgcagtatcg ctctttgaag aaatagattc cacaggaagt
    27961 gatatacatt caattcgctt gtcggcttgg aattcttcaa acttattttt gatgtgattc
    28021 caattatttt tctgtgtaat cccgtttact aagtctacat atactaatgg atgtaatatt
    28081 tgaaggggtc tccaagcata attaccatct ttattagcta atattcgatg attaacatca
    28141 actgcctcag agagcgatct cttatgtcta actagttcag taaatgattt gttttttaat
    28201 aaatccactg ctttctcaat gcctactgat aaatcaatat aattgggcaa cgatgtacta
    28261 aaaaaacttg atgtttttaa aaagaattgc tttgcttctt gatgattcat ctctaaaata
    28321 ctttttctag tcctagtcaa attcaaaatc tcctagatca attaagttgt aatgtaagag
    28381 gataccctaa cgttacatat ctcattcatt attataccag tatttcttca tgacacataa
    28441 gggtgtaaca taataatttt aaacgaaatg actacaagta gtcattgaag taagtcttca
    28501 taagatacct gtaggatatc cctaattgct ctcaattgat ctaacttaat gtgttgccgg
    28561 ccaccttcaa ttttaaccaa tgtttcccta gttatagcaa ttttatgaag ctgtaggtct
    28621 ctaatcagct cggtttgacc aattcctttt tctaatcgga ttcgtctaat attgctaccg
    28681 attacatttt ctttatcaat aattttttcc tctttcaaga atagcacacc ttttggacta
    28741 aaattagtcc tttttcttat taatcttaaa gattcggtat gctacaatgg gactagtatt
    28801 agtccacatt caattttaag gaggaatttt tttgaagaaa tttgcaatca ttctaacctg
    28861 cgctttactc atcggaacta taagcgggtg taccacttct gaaacaagtt ctacaagtac
    28921 ggaaactagt acaacaacct cagaaaagaa ttacccaata catttttttc cggttccaga
    28981 tggatttgaa gcttattatc atgataaaaa actagatgtc cctttatcag aaactgaatc
    29041 tactgaaaag attttgccaa ttgaaattga aagaaatcaa gacgatataa aactaaaagc
    29101 tgatcttccc ttactgaaca gcacacaaat tgatagacat gaaaatatta aagttaatat
    29161 tgaaaaagga gcgttagcaa aactttatac tgaaaaagtt gaacaatttt ttaagtctgg
    29221 tgccaataaa gacttttcaa aaataagcga ttattcggag aactttttta atgaaaccca
    29281 agatgaaatc atgaactcaa cttttatggc tgaagatatg tacaatatga cattaaaaaa
    29341 aataaaagct tacgaccatc cgttaaatct gacactaaat aatggactgc tttcttttgt
    29401 attagcaggt tacgttgact atgaatattc accagattat ttggagaaac ctcttcaaca
    29461 cgagaacaat gatattaatt ttagatttgt ctacgagtca aaaagtaaaa catggttagt
    29521 tgatcaatta agcacgataa acacaagctt ccatgaatta cctaaacctg aaaatgaagt
    29581 tgagatggtc attaaaatct tctaaaaaag aagcgttgaa ggagaaatat tcctttcaac
    29641 gctctttttt atatgcttag aaacataaat aaattgtata ctttcttttt agcccctatt
    29701 acttttcacg aaaaatatct ttttttcgac gctagcgttt ctctacttct aatactgtac
    29761 acagtttttg tattattgaa aaattactca ttatttagca ttaatccaca tcgttttatc
    29821 aatcgacctt catactaaac tactttaaag tcatcttcct tctcgttttt cattaaatca
    29881 gacacataag cccatgtacc cgttcgttgt aaataaagtt cttcttgtaa caactcccat
    29941 tttctcttag aaatcataat gacgccatcg ttcaatccat ttttagaatc cctagtaatt
    30001 tctatttcag aatttgaatg aactacttct tgcaacactt tacctatatt ttctttgaag
    30061 tttgttggag taatagtatc caaaatgaac acctctcttc tctatacctc tattatgaag
    30121 cgcccatcaa ataaagcaag cgttgaggaa taattctatc aacacttgct ttattaagct
    30181 ttcattttgt agtttgacta aaaccaataa tcttatttct aaactctcga aaaacttctt
    30241 gtggctgata atagtctgca tctatttcaa atgtttctga gaataattca ttgaattttt
    30301 ctactgaaat aatgatttta ccattcttct ctcgactgtt ttctattatt tctgcttcta
    30361 attcaaataa atctagtgac gaattaaaat cataaatcct gtcatattga acaaaaaaat
    30421 caagaaaaag ttgctcaaac tctttcttat ttatcactag tgtttcaagc agatcaactt
    30481 tattttcttc agtcattctt ccaatttcct cactttcgtt ttcaaaaatc acaaaaatga
    30541 tattaactta aaagccacta acaaaataag acttacaaat taaagggtaa tccaacaaaa
    30601 taaccattcg ctctacgtac tacgatttgg tagtcctgcc tttcaatcgg taattcataa
    30661 tagtaattta ctgtttctga tttaccactt tcaatatact caggattatc caatatcata
    30721 gcatactcat aaagctcttc accatcctta ttttcaatcg accattgttg cggacgtatc
    30781 ggattttctg tatcattttt cattgtatag gtcacttgta atacacgatc atgctgtgca
    30841 aattcatttc ttttttcggt cagttcaata tttttaaatg ttagttcaac cccatctgcc
    30901 tgataagttt cacctatttt taaatctttt gttacaattt ttattggctt ttcttctgga
    30961 aaatacctgg ctttaattgt tagataactt ccaaaaagaa tcaatcctag tagcacaaaa
    31021 aaaattcctt taacgagcca ctgaaacggg aagtaaactt taaacatctt ttttctcctc
    31081 cgttttgtat ttggttttta gagaacacga taacttttga tcaataccat ccaacttttt
    31141 cattatactt gattctagtt ctgaaattgt ttgttcaagt ttaatgcttt caggatcact
    31201 aaatttttta tttgattgac tagccaacat tggtaaattt gaaaccatca cacggaacat
    31261 atttgctttc gttccaagag ttcctttatt cttctcataa aagctgtcaa acaatttttt
    31321 tgtttccttt gaacaatata ctttaatata cggatcagac attcttttcc ctctccctgt
    31381 ttacttaaaa atccatatca tattgatttt gttgtttttg ataatcaatt cctcttgctg
    31441 tttcttcata ctctctccga gctttttcaa tcgtaccatc atcaattgca cgattaaata
    31501 aataaagaac acgttttgtt tcttgaatat aacgcttctt aaaattacgt tttaaagcgg
    31561 gttcagtatc ttgaatgtta aattggtcat aatcagttga taaactctct gcgatatcat
    31621 aaacaacttt tttatacacc aaatttacac atttcttctt atattttaaa ggttcctctt
    31681 ccactgcaaa tccaaagaat tggtttttat tctcaccaaa aacatccaat aaattttcta
    31741 ttctgtcctc tatttcaaat ttatatttat cataaaattc ttcataatct tttgatgatc
    31801 taagaaatgg tatattctca ttatctaatt caaagcgttg cgctcgttct tgccaattaa
    31861 atctactatc cgctctacca tttaacgatt taccaagatg tcgaatagca atttcagtga
    31921 gtacctcttt agattgaatt tgctccgctt ttttattttc tgtgaacaaa tcatcaagat
    31981 aattcatatc atagttttgc cctaaacgct ttccgccaat ttttaagatt aactcgcctt
    32041 cagaatctaa gagtttgtac ccaatacgct gatttttggc aaaccggtaa gtctcaatag
    32101 aatggttttt cttcaattcc gcatgaaaat catcataatt tttcgcatac tgagcaactt
    32161 cagaaacagc tagttttatt ttttctcgat ttgaaatctt attttcagtt ctaaattcac
    32221 gttctttcca attttcacga tctgcaacta aatgattata cttatacata tcaagtgggt
    32281 taattccatt atcaataagt atattatcat tccaagcctg caaaactcga atatcattct
    32341 ttcgaatatc cattttcttt cctgttagct gatcgtttgg cgaaatacca aagtgattgt
    32401 gaacatgccc tttgtctgtg tgtgtgacaa ccaaaattga ctggttagga aacatttttt
    32461 ctgcccactt aacacccaac tcatgtgctt tttcagcgga aatatcttct agtggatcaa
    32521 agctttgtgt aaaatgccaa agctttattt tccctttatc accaaaaatt tcattggttc
    32581 gtttaaattc ctcaatagca tttaaatcat tcgatacgcc aattcctgtc acgagttcag
    32641 aatcttcttg tttatttaac atatatgaaa ttgtattatg aatactccta ctttttgaag
    32701 caatttttat aatcgagccc ataacttatt caactctttt tccaagcgat tcaatggatc
    32761 gcttattgat tttatttgta tcattaagtc atttttttca gcatatagcc gctttaatcg
    32821 ctcttgctta gttgtaaaag ataagtaaac actctgatgt tcttcttttt gtatctcggt
    32881 atctttttta tttaactgaa cacgcaaata atttgctgtt ttcactaatt gattcaaatt
    32941 tcttcctatt gctagtaaat gaaaattaat ttctttatat tgtcgatcgg tatattttag
    33001 acttttccct gcgttgtcta ctgcgatttt cttcacgtac attggaacag ataaaccaaa
    33061 aatgtctgct gttttttcta gctcttggta ctgataatcg tctactcgaa actttatcgg
    33121 cctattttgt cgtcgactat cttcattacg tttatatcgc tttcgccttt cttctaatgg
    33181 tagtttactg acatcaattg ccatgcgcac ttctcctttt caatattatt tttaagttca
    33241 aaagaagcaa gcgaggggaa agggaaccct tccccgcttg tcgagggagt aaactcccta
    33301 cgagcaccct catgctccgc attttatcga gattagatag ccgataaatc agctacctaa
    33361 cactttcttc ttgcgcctct tctcgataga aaattcgata cgctgtctct ccttttcttc
    33421 tcaaaaattg ttggaatttc gtttccatca attgatcgct tgcaagaaat tcgtgtacta
    33481 gggtaaattc gctattcgcg aaatttaccg ccttttgcca tttttcttga gtaccttttt
    33541 gattaatttc aaaagtttct tcaaactctt ttactgatga aattcctgtt ttttcataga
    33601 catactttcc cagttcggga taaagttttc tctccaactc ggcgagttct tttttcaaat
    33661 ctgcaattga cttttgtttt ttccttgcca tttttcatgc tcctttttgt atgtgactaa
    33721 gttcattcat aagctcattt ttcatcatta attcttcttg aatcatcagt tcaatataat
    33781 ttgtgaccgt gattttttca tttgttgctt tctttactga ttcacataat tcgtcaagtt
    33841 ctaagaaatc atgtgtacta atctgtagaa ttaattgcat gacaatcacc tctttatttt
    33901 ttaaatagac tatcaaacag cggatttggt ttatcagaaa tatcctgaaa cagtggatta
    33961 ttttcataag taaatcgttg acgtttcttc tccttcactt cttgttctac aatcactttt
    34021 tcgttaggtc tttcttttcg ttcctcgaca atatttattt tttgcgtctt atctccctga
    34081 cttgcttcag ctcttgtttc acgtacttct accgtttttg gttgatttgg cgcactactt
    34141 tgtacatttt ctcgtacgtc tactgttcga tttccacttt gactacttgt agtatcctgt
    34201 aagtttaatc gaacatctac cgttcttgtt tgacctgtac tgctactttg cacattctct
    34261 ctgacatcca ctgttcgatt tccactttga ctacttgtag tattatgcaa gttttctcga
    34321 acatctactg agcgcctatc ttgactactt gtagaatttt gtagattttc tttaaccgat
    34381 ttttctaatc cggtatttga atttttagct tcttggattc tttctttggt caacgcttct
    34441 ttttcgtcca tattagctcc tgtacgccct tctacacgtt tccttaacat ttcctcacga
    34501 ttcattgctt caggcgtgta ttttgcttcc tgtcgcttct gattaattaa ttcttcagca
    34561 gacttagctt gaccgtgcat agcattttta cgttcttcaa tatcttgttg aactttttgc
    34621 tgaattgcac ttgcataatt agtatttgat tcagcaatat ttttcattgc ttcacgcata
    34681 cgttcagaac tagacataat tctatcggca ttctcaatct tagccccatc ttttctatcc
    34741 gaaagacgta ttggcataga atcagcatat tttccagttt catcttcttt gtttttagct
    34801 actataggtt tgctattttt attaatagcg gacacggtac catcatctaa accttctttg
    34861 aatttattct tggtatcatt agccatatca cgcatactct taaatggttt tgttgctctt
    34921 tcactagcca ttgtagctcc atccgaagct aagcctgata atccacgttc acgagcatac
    34981 ccaagcgttt tccccgtttt attagctttt tgagaaagtg attgaccaaa gttgcgttca
    35041 ggttttcgtt cttccccttc cgtttgatcg tttccaccac tatttttccc acctttagat
    35101 cggttcatgc cacctgttcc tttacgaaac agcattgcac ccattccaaa agcagaagca
    35161 agttgcccat agccttcttt gagtccaata tccacaccaa agtaacgcat gactgttcca
    35221 ctgcctttga ttaaaacaaa cacagcacag atataagcaa ttgtttttat aaaaatattt
    35281 gttgagatac cttcgccagt atttaagtaa tttatgaaca ttgcaaacat agataatcca
    35341 aacccttgaa atccgactgt caaatagcac tgtaaaatat ctgacaaaac ttgttttgat
    35401 cgttgtcctg tttctaagtc agtagcaaat actaaaactc cgagtacacg tttgaatgct
    35461 agctcgagta ttgctgtaat tataatgaaa gcactaaaaa catacgctac cgctaaagca
    35521 atcaatccaa atgaaattcc ccacaggttc gcttgatagc gataatatcc tgatttgata
    35581 ccatcaacaa aggttgacaa aaaattatct gaaaatttag tagcaacaaa ttcattatca
    35641 gaattttcaa ctaattcata acgcaggtta tcagctgttg agttctcttt ttccatttta
    35701 tcaattacat tatctgtcaa tacttgcgta agatccgttt tccaaaaatt ttcttttgtt
    35761 agattgttcc gatcattcgt tttatcgatc atggaatatt gatccgtttt attgatataa
    35821 gctaaatcag taaccccttg ttcaatcagc gaccatgcca caccgccatc ttgattgtta
    35881 atactagttg cgtcattata aagagtcttt gcaaacatta ttcctgaaag tttttctgtt
    35941 gatccaatca aagtcggcat taaaagaatt aatactatcg acattacaac attcattcca
    36001 acagatttta gatcaactgt tccttttcca gtcaccattt tataaccaat aatcactaat
    36061 gagagtacca ttaaaccaat aacaactgta tttaaaactg actgatagac tttgttcaat
    36121 ccagcacttt ccacaaagct aaacaaatct aaaacctcgg gaatcatatt ttgaatgcca
    36181 tcgacaacag cgaacattga ttttataaca gaccaaccta tccacatacc gaactggctg
    36241 taaaaatttc cgttatattt tttaagataa ttctgataaa gtggattagt taaaaactca
    36301 gtttgactct cagtatcatc aaaccagttg aaaatactgc cttctgcaac gttactcgta
    36361 aaaataatca tagctatgag aataagaaaa ctaatcaaca accaatttat ttttctatta
    36421 tcaatctttt ttttaattat tttcattgtt acctccctca gcccattttt ttaggctctc
    36481 agaaagcttc tgagccattt ttttattaac gatgatgtga gttacgtaat catcattaac
    36541 agctcttaaa tctagaacaa tagtatttga gcagatactc tcgattaact caagagtatc
    36601 tgcgttatga tcaagacagt aaatcttatc tactagatga ttttcaatca aaataacccc
    36661 tcccgtagtc aaagttctca attttatgaa gatatccctc tacttcattt aaatcaattc
    36721 tattcttatt gctgactaac ccgttgtaaa attctttttg tagattatat ttatctgttt
    36781 cttgaatctt tttatataaa tcaaccaggg agtccctgtc tttaaaaact tgcttgaatt
    36841 gttcgcttgt atatcggttt tcattaattg caacaactgc ttgaatttca ggccattttt
    36901 ctttcaactt aaaataacgg ggaacgctga aatagttctc aaaaaagaag tctcgtgctt
    36961 catagtattc tctattttgt ctttttatat cctcgacaat ttcgtatcgt gtagagatct
    37021 tcaaagctga actttcgtta atttctgttc cttttcgaaa gactttcact tttgaagggc
    37081 gttcaatttt ataatttatc ccctttttac ttgaataact tttgatacga ccatcaaatt
    37141 gaaccatatc tccttttttt aaccacccaa attttagaaa ttgtttagtt aaattcatcc
    37201 aaatgtggtc tgtgaccaac tctaagttat ccccttgaac aatttttaaa ttcgataaca
    37261 taaaagtagc attttcatac tcttgaccaa acttgtattt atccttttta tatccgttaa
    37321 attcaaaggt accttgaaat gtatgccgtt tcttatctcc taattttttc aatttttctc
    37381 tcaaaataat caactccatc atttaatata tttttgtgat ggtagatact ctcgattaac
    37441 acaagagtat ctgcgttgta atcaagacaa taaatttgat atattaaccg tttttcaatc
    37501 atattattaa tcctttctaa cctatttttt tcagtgtctc tagcatatcc agtctactag
    37561 ctttttcttg cttagctatg tcctcccagt ggttcctagc tgtggtgttg ataaacttca
    37621 tttcatcaat ttcttcaccg agattcagtt tttcatttat agaattaaaa agtcttgtta
    37681 gcattttgtt tgttatatca aaatagtctt gacctcgaat ttctatttta tattctcttt
    37741 caattgaatc tttcatacta gcaatcaact taagatactt ttctctttga acttcagtat
    37801 atctatcacc tagtctggta attatttgaa ttcctttctg atttataata ttttcaaaaa
    37861 aggaattctg atcttgatta atctcttcta tactatcctt atcttgatta gtttgatctt
    37921 gactattctg atcttgactt aactgtgtat ccgatttgac gtcgcatggt ataccagctg
    37981 gataccattt ttccatcaga tcaactctta atggttctac ttgaccagac tgcaaaatca
    38041 tatcaaattt tattggcttt agctttgaga aaaattctgg ttttaagttc aataacttga
    38101 atcgataaat agaaggttta tacctatcga ttcgtatatt ttgattttgt aaccagtggg
    38161 gtagaaacgc taacaaatct tcatttaaaa aaaatacaaa accttttgta aaaagtatct
    38221 ttacatcatc atcgggtgtt ccgagcattt tcgtgtatgg ataagcttcg acaattccgt
    38281 catcatctgc gtttgtgttc agatatacgt ataataattt tgctgaatct gacatcttca
    38341 taaaacttgc attatttaaa aatgatttag ccagcattcg tttttctgcc ataaaaatca
    38401 cacttcttcc tatttgaatg ttaaaatgta gtcaaataaa gtttagctag aactttatta
    38461 ttgagcgttc ctagtggtct gcaaactaac gggaacactc ttttttattc ttattaaaac
    38521 cagcaatact agttcacctt ctttcatcct tttacatcca attaaatttg atgctgtagc
    38581 atccattttt ttacctcttc ttttgaatat agttcaattg tgtcaaccac gataataggt
    38641 aatcctaacc ttttaaactt cagaaaagtt ccatatgata cgtttagaaa ttttgccatt
    38701 tcttttccct taagaaaagg tcgttctaat ccgctgtcta ttcttgcttg atcaatagct
    38761 tcttttgtca cttcaaacac atgtgtcttc aactgatttg tttgatcagt attcaacatt
    38821 acactgactc cgatttgctc cattaaaaat tcccactttc atattttcat caataagcca
    38881 actcgccaag ttgtttgtta ataatctgat ttcaataacc aacctattat tttttgataa
    38941 acatttttcg acacactttg aacttcgaag cattcaattt ttttaagagt ttgccttgaa
    39001 attccaatta attctgctgc tttagttttc gtaatcatca actttcctcg tctctctcga
    39061 attcttatac taaaatcctc attaatttga aacataaaca tccctccatt tttatttttg
    39121 catttatccg tttatccgat gtcggataaa tagattttag tatatattat tttgatagtc
    39181 aattaaaaat atacattttg gataaaattg ttcatttttt tatccaaatc atatattata
    39241 gatagtaaga ggtgaacttc attgactcaa aaaaacagaa ttaaagaaac tcgcgaagaa
    39301 cagaatttaa cacttaaaga acttagcaat ctgtcggata ttccgtatca aactttgaga
    39361 aactatgaga ttggtaaaag aaaacccaga aatgatgaag tttggtggaa gttaggtacg
    39421 attttaaacg tccgtgggcc ctacttaaaa ggagaagata gttttaaaac aaatgatgaa
    39481 ttgcatattt attatctaaa aaaaagtcat acaaattttg aactgtctaa gaaagaagaa
    39541 attatagata taatagataa actaaacgaa gacggtttag atgaagcctt acggcagtta
    39601 gcactattat caaaaataga tgatttcaag cggtaactta cttatcatca tgtagactat
    39661 caggtatcat aaactaattc ctcaatcagc caactcgcca agttatcaga ttggagagat
    39721 tagttatgtc aatacaaaag tacaaaacaa aaagcggtac acgatatagt gtccgcttat
    39781 atgttcgtaa agatgaaaat gggaagcaag aatactatgt aaaaaaaggc ttcaaaactg
    39841 aaaaagaagc caagttacac gaagcaagaa aaaaggtcga gattgaagat atgggctatc
    39901 acagaccttc taatgactta tttagaacag tctatgaaga atggttgccg tcttataaaa
    39961 atcgtgtaca agaaacgact tatcaacgaa caaaagacct ttttcgcttg catatcctgc
    40021 caaagttcgg agacaaatcg atttctaaga ttactcctat ttactgtcag aatgcaatca
    40081 atgaatgggc tgtaaaatat acaaatatca agcaacttaa atcctacagc tctcaaatat
    40141 ttgagtatgc aatcttcgca gaattgttac agcgtaaccc tatgacaaat accaaactgc
    40201 caaaacaaga aaagaaagaa tccgaaaatt atttctcact agaagaatta aaagagtttt
    40261 tggaaattct caataaagaa gagtctttaa aacatatcct gatctttcaa cttttaatta
    40321 ctaccggtgt tcgcaaaggt gaattatcag ccctacgctg ggcagatatt aattttgaag
    40381 aacagttact acacatcgga aaaagttatg caacaattcg cactgaagat ccgaatgcta
    40441 ctagaaaaac aatcaggatt cagaagaata caaaaaatgt ctcttccgaa cgaattttac
    40501 cgattgatac tcaaaccatc gaaatgctga aactttggaa aaaagagcaa gcagaggtac
    40561 ttttacaatt cggcattaat gcaaatacca aaaagcaact tatctttacc tatgtaaatg
    40621 caaatggcga tgttaaccaa cctttacacg cagattattc caataatatt atgagacgtt
    40681 tagagaagaa atataaattt aagcacgtta ctattcatgg attgcgacac actcacgcca
    40741 ctttactttt agaaggcggt gcgagcatta aagaagcaca agatcgattg ggtcataaaa
    40801 atgctgaaac tacgctcaat acttattccc atgtaactga aaaagcgcaa cgaaatgcgg
    40861 tagacaagtt tattgcttac actggattat agacaaaaaa gttgccgtca ttaccttttt
    40921 cattaccaca acgaaaaaaa gcaccttcca actgaatgga aagtgcttga aatcgttggt
    40981 ataacaacga ttaacgctta gagaattgtg aagctttacg agctttctta agacctggtt
    41041 ttttacgttc gaccatacgt gcgtcacgag taagtaagcc agcacgttta agagctaaac
    41101 ggaagtcagg atcaacttct agcaatgcac gagcgatacc atgacggata gctcctgatt
    41161 gtccagcgta tcctccgccg tttacgttaa caaatacgtc atatgcgcct tttgtttcag
    41221 taacagcgaa aggttgattg attacttcac gcaagtcagc atgtggaatg tattcttcaa
    41281 catctttttt atttacagta attttgccag ttcctggtac tagacgtacg cgagcaactg
    41341 cgtttttacg acggcctgtg ccgatatatt gaacttgtgc caatgaaatt ccctcctatt
    41401 agattaagtt tgtgatgtct aaaacttctg gttgttgtgc tgcatgtgga tgttctgctc
    41461 caccgtatac gttcaatttt gtaaattgtt tgcggcctaa agtgttttta ggaagcatac
    41521 cttttacaga agtttcgatc aaacgacgag aatttttagc acgcaattcg ccagcagtga
    41581 ttgatttcaa tcctcctggg tagttgctgt gacggtaata aattttgtca gtcgcttttt
    41641 tacctgttaa tttcactttg tctgcattga tgacgatgac gaaatcgcca gtatccaaat
    41701 gaggtgtgaa agttggttta tttttaccac gtagtacaga tgcaacaact gttgaaagac
    41761 gtcccaatgg aacatcagtt gcgtctacta cataccattt acgttctact tcgcctggtt
    41821 tggccatata tgttgtacgc acgttatttt cctccaattt aagttctgat gtttgacata
    41881 cacttcgagt ttccggggct ctttgtgggg caaacaatac catttaacat attacccgct
    41941 aatctagtca atgtcaacgt ttttctgctt gattgaaaaa tttatatgaa actttacttc
    42001 ttttctttct tttatataaa agggtcgttt cctgtcaaaa tgaaaaacaa aaagaggctg
    42061 tgacaaaagt cttgtcacaa ccccttattt tgaataaacg gtgttctcct gccaactcct
    42121 cggtcacaag tcacaatatc cataaaacat aagaagctgt tttttaaaat tgtttcttgt
    42181 gactcggagc tgaacggcag gcttacaacc tcttggtaaa cggtgttcaa tcagctgacc
    42241 ctcggtatta gctcaaaaaa cggcaaaata tgaggaacta ttttgacgtt tgtttctcta
    42301 atactcaggt caaaacgctg atttcacaac ctctttttcg gtcaagttca acaacagttt
    42361 ttacgcgtcg atctctggcg ctttgcccaa atgagcttgg atcatccaga tacgtttttc
    42421 tgtggctgtt ttgaattcga taaagatatc ttgtgttgga tcgtcgcctt cttctccaga
    42481 aacttcgatt cctttttggt aaagatctgc tagataacga tagcctgcaa caagtgtttc
    42541 caaacgttct ggaatagtac gatcccagcg gccaatttca tcagggattt ttgtgttatc
    42601 tgcaaattca cgcaatgtag aataaggtga accgtctaat gtgatcaagc gttcggatac
    42661 ttcatctaac tgagcgttca aatcatccat gaactcatcc atcattgggt gcaatgtaag
    42721 gaaacctggt cctctcatgt accaatgtgt ttggtgaaca acaacagaca tttggcttag
    42781 atctgcaact aattgattta atacttcttt ggtttgttgg aatttcatct ttcttgcctc
    42841 ctaacatttt cttacactta aaataatagt agactttcaa tgaaaagtac aacaaaatca
    42901 tttacctgag aacgattttc agttcgcttt tttatccgta aagccaatca tttttcagaa
    42961 tcagctaatt cttctcgcag ttgagcaaat tgctgataag tctgtgctaa atgcttttgt
    43021 gtcgaaacaa ataatggata gattttctga tattttttat gatcagtttc ttgtactcca
    43081 acttgctctt tcaattctat caattcctgt gcttcactga tactttggat ctttccgatg
    43141 cttctccagc ctaaaatcac agctcctaat gcggatgctt ctgtgacagt agggaaaaca
    43201 agcgggtaac ccagtacatc agccatcatc tgacgaaaaa tcggagattg agcaaacccg
    43261 cctgtagcac ggatctctgt gagctgattt tcctggcaaa ctccttttaa aatccgataa
    43321 aggttgagac agatcccttc tagaatcgcc ttcatcattt ctttttctgt atgttgccgc
    43381 tgtaaaccga taaaactgcc aaacgcatct gcgtcccaaa gcggtgctcg ctcaccaagt
    43441 aaatagggat gaaaaatcag accattggca cccgctggca caaaagcgat agccgaaagc
    43501 agtgcatcat atggattttc tcctttttct ttagcagatt gaacgacttc ctgtaaaaat
    43561 gtatgccctg cccaatcaaa gatgccagca ccattgctag tcgctcctcc cactacccaa
    43621 tgtttctgat ccagaacata acaaaacgtc tccatttctg gatggaactg aggctgagta
    43681 gtaataaaac gaagtgctcc gctcgttcct acggtcaaag cggcgatcgt atcaccaaaa
    43741 gcacctaacc ctagattaga aagcggcccg tctgcccctc ccaaaacaaa tgatatatca
    43801 tttggcaaac ctagttctgc tgctgttttt gatggtagac ctgttacttg ataggtggaa
    43861 ggaaagactt gcggcaattg ctctattcga atgttcaagt agtcaagcac ttcttctgcc
    43921 cattggaatt catggatatc aaaatatcca gttcctgaag ctgttccgta gtcgctgatc
    43981 agttcgccaa acaatctata aaagatatag tctttgatac cgacaaaata agcagttttt
    44041 ttgaataatt caggttggct gttttgcagc cacttgattt tgttcaatgg tgtcattgga
    44101 tgaatcggcg tcccagtctg ccgataaaat tctttgccaa gcacggtata tttcagtttt
    44161 tctgcttcgt ccgctgctcg gttatctgcc caagtgatca ttcgagataa cggtgttttc
    44221 tcttcatcca acaatatcag gccatgcatc gcagaggaga aggagacaaa ttgaatgatt
    44281 gtgtctgaag gcaactgttt aattacttct tttataacgg tgcagacacc ttgaaagatc
    44341 aattcctgat cttgttctgc catcccttgt gtttcttgga tcaaagggta gcgaaaataa
    44401 gcggatgctg cttcttgggc ttcatctgtg aaagcaactg ctttggtttg tgtggttccg
    44461 atatctaatc cgattgaaac gttcattttt tcacctcaaa ttttatgtat gtacaaaaat
    44521 ttagtttaag cttgcgtatc ttggttttga aaagggggag atggcgtgtt actttatttt
    44581 atcattggtt gctgtatcgg atcattttta tgtttaaccg cccagcggat tccgttaggt
    44641 cactctatta tttatcctag atctcattgt gtcaaatgct gtcgttcgct ttcttggtat
    44701 gaattgattc cgattctctc gatcatcgtc caacgatttc gctgccgcta ttgcaggtgt
    44761 cggttgccct tctactattt gttggcagaa gccttatgtg gtggtctttt tgcctggttc
    44821 tttacttttt cttccgcaag aaatttttcg acgttcatat ggatgctttc ggctttgcta
    44881 ttttcgttga tggatttatt ttacttcatg gtccattctc acacgctatt ctgttcttgg
    44941 gcaattttat ggattttttg gttgcaggcc ggcgtcttcc aatggcaaag tgtgctgtta
    45001 acgtttatcg taggcggtgt gtgccttcgc tatggtcaat cctatctcgg agctggcgat
    45061 actctgttga tgctttcttg gagtggtggc ttgtctctag aagagttgct tcagatcttg
    45121 tttcttgcta gtctgtttgg aatatccgtt ttttctgttt actttatctg tcataaaaaa
    45181 aagttggaaa agctgccttt cattcctttt ttgagcagtg cgttgctgat tgtccttcat
    45241 cttaggtatt gaaaaaaggt tgtgacaaac gacttgtcac aacctctgat atatagtgtt
    45301 ctcttaccaa atccttgtga cttggagcta ggcgacaggt tcacaacctc tccactaaat
    45361 ggtgttcaat cagctgaccc tcagtattag ctcaaaatgc tggttttaca acctctgata
    45421 tacggtgttc cataagtagc tttttcggct tcttatttct tgacgcccca atgtcgacga
    45481 aggaaacctg cacgtccaga accttctcga taaagattgt aatggagctt gtttttcttg
    45541 taataatcct gatggtaatc ttctgcagga taaaattcgc ttcttggttc gatttttgtc
    45601 acgattggct tatcgaatcg cccgctgtct tgcaatgctt gttttgaacg ctctgcaata
    45661 tttcgttctt cttcatcatt atagtagatc actggacgat aagaatcacc gcgatcagcg
    45721 aactgtccta atgcgtcagt cggatcggtt tgctgccaat agatttccac caactgatca
    45781 taagaaataa cttctggatc atattcgatc tctactgctt ctgtatgccc tgttgtgcct
    45841 gttgttactt gttcataagt tggatttggt acatgcccgc cagtataacc ggatgtcaca
    45901 gaaatgatcc ctggctgctc ttcaaatggt ttgaccatac accaaaagca tccgcctgcg
    45961 aaaactgctt tttttgtcat ataaaatccc ccttttttct catcatacct tgatttccaa
    46021 aaggaggata acgttttgct tgtgacagaa aaaacggaaa ctattatata cgtgatacgg
    46081 cttctgataa atgccaaaac gaacgtactt gatcaaaaac ggttaaatca ggaatcacat
    46141 attcagcaga aggaagattt atgttttcac ctattcccaa tacatgcatg ttaccagcca
    46201 aagctgcttg acaaccagct tctgaatctt caatgaccaa gcatgcattt ggcggtacat
    46261 tcaattgctg tgctcctttg agaaaaactt ctggatcagg ttttgctttt gatacttgcg
    46321 tgccgtcaat aaggacatca aaataacttg tcaaattcgt tttttctaaa atgaggcgtg
    46381 catttttgct tgctgatccc aatccgatct tgatgtttgt ttttttcaag tactcaagaa
    46441 cagctattgc accaggcaaa acggatgttt catccatttt ttgaatcgct tgaagatata
    46501 gattgttttt ttgctcagca aaggctgatt tctctttttc tgagaatttc tgttccattt
    46561 ttccaaatga cagcaatcgc tctagtgact cggttctgga tattcctttc agttgctcgt
    46621 tttctttctc agtgaatgga atggacagct ggttagctaa aaccagccac gcttcgtaat
    46681 gataacgagc tgtgtctaca agaacgccat ctaaatcgaa tagtgctgct ttgattttca
    46741 tcgattacct ccttgaaaat gaacgacttg aagtaaagat gcgatgtttt tagctgtgcg
    46801 atgaagatta tcagtggctt gctgtaaagc ttcttgtaaa ggcacagctg caggaaggat
    46861 cggaaaaacg gccgaaatgc caacatctgc tgctttttcg cttcctttac caacacttcc
    46921 gcaaatagct atcacaggaa cgccctctgg tactcttcta gcaatcccaa ctggcgcttt
    46981 tccttttaga ctttgtccat ctagacgtcc ttcgcctacg attacgaggt ctgcttgctg
    47041 tacccgttta tcgaactcca gtaaatccaa tacgtagtcg atgccagaga ctattttccc
    47101 tgaagcaaat gctaacagtc ctgcacccat tccaccacca gcactactgc ccgatgcctc
    47161 gattacttga ggggcaaatc tcatataaaa atcatgcatg gcttggtcag ccactgctaa
    47221 ttcattttct ttcaagcctt tttgtggtcc gaaaacaaaa gaagcgcctt cttttccgca
    47281 taaaagatta gtaacatcag taatgacagt gattttggct ttaatcagct caataggcac
    47341 gttcgtttta tcaactgtag caattttacc tagattttct cccagtgctt ctactttttg
    47401 attatcttga tcgtaaaaag cataacctag accttctgcc atgccgatgc cgccatcgtt
    47461 ggtactactt ccgccaacgc cgatgatgat gtgtcgaaca ccttgttgca acaattgtcg
    47521 tatcagttct cctactcctc gcgtggataa cctaagtggc tgttgttggt ttagtgggac
    47581 atctttcaat ccgacgattt ctgccatttc aaaaatcgca gtttgaccgt ctgaagcgta
    47641 ctggatttct ttgtttttgc caaatgcatt agtaacgact gctgtttgcc gcttcaacct
    47701 taaactgtct gctaatgatg aaaccgttcc ttctcctcca tcgcctatag gtagcagatc
    47761 atattcagcc tgaacaaaaa cttcttgaaa acctgattga atggcttgtg ctgcctctaa
    47821 ggctgtcaga ctttctttga aagaatctgg cgcaatcaga atacgcatta ttttcccctc
    47881 cgttccaaga tcagttcttt ttccagctgg tattggtctc cattgacaaa aataggtaat
    47941 gtttctttcg tctctttttt tattactatt tgtttttttg tcaaaacaaa tagcaacctg
    48001 tgatttttcc aaataaaagg aaaagaaatt ttttcccatg ctgaaggaag tcttggagaa
    48061 atagaaagag ttccattcgt tactgtaata cctgaaaaac caaatataac tgctagccat
    48121 agtgctccta atgaagcagc atgaattccg tcatctgatg aatgcggatc tggtcctaaa
    48181 tcaatcaggc acgcttcttg gaataaatga tacgcccatt ccatttcttg gatacggcaa
    48241 gcctctatgg cgtgaatcgc tttactcaac gatgagtcgt ggattgtttt gttttcatag
    48301 taatgcaaat tcttagaaac gattggttga gaaaaatact caggtaataa gtataacagc
    48361 atgacaagat ctgcttgctt gctgacttgg agttcattta cttcgctacg ggcataatca
    48421 agtaaaatag actggctgcc aggacgttct ttgtaagtgg tcaaatcaat aactggctta
    48481 ctgaaatacg tgtcatcttg cggaatcagc tgttctttgt taggcactgg caaatataac
    48541 ttatctaaaa aattttgaca ttctttcaaa aaaagcggat cgccagcttg atatttaaca
    48601 gctaaggcca cattataatg cgccagatag ttcgtatatg cattattgtc gatatattct
    48661 gtgtattcat ctggaccaat gactctgtgt atctctaaat gatcatcgac ttttacagct
    48721 ctgctcagcc aaaaagctgc tgtttcatga atgagcgttt ttccctttgt ttctaaaaac
    48781 gattgatcct ctgttgcttg gacatactct tgaacggcat aagcaaggtc tgcactgata
    48841 tgatgttctg cggcagctga agcaacttct tgtcttgttc cggttttgat attcaatgca
    48901 gcaaatttgg gtgtctcttc ctgaccagtg tgtgcgcttt cccatgggaa aagtgcacct
    48961 tgatagtgat aatctcttgc tttttgccgt gcgccttcta atcgatcata acggtacagc
    49021 agcaaattct ttgctacttc aggaaactga tataaaaaga aaggcaggat aaaaatttcc
    49081 gtatcccaga aaacatgccc tttataacct tcgccagtta gtcccttcgc ccctacacta
    49141 acacttggat cattgcgggg agtcataatc tgtaaatggt aagcagcgaa gtccatcgct
    49201 aactgatcga aagaagaatc gccttggatc gttatccgat gctgatgcca aaaatctgtc
    49261 caataagaca tcgactgctc taaaatttct gtataactaa cgcttttctg ggcttgggca
    49321 atacttttct taaacgggtc tgtttgctga agagaggtag agagcacgat gatcttctcc
    49381 agcgtaaagg acgtattttt tctgatcttt tctgaaaagg aagcggtgat ccggcgattt
    49441 tttgcttgga atacacctgc tttattgaat ttagctgcaa tcccaatatc aattttactt
    49501 tctgttgtct ggtaggatgc actgatcaaa tcgtcaccaa atactcgcag ttctttttca
    49561 accaactgct gtgtaccaaa attggtttgc tgtccatcga tacccgtttt cacatctact
    49621 tggcagtctt cggtcaacgg cttgatgacc actttcaggg ctgcctgatg gagattattt
    49681 tgatcagcaa cacgacaagt aatgacttcc actttttttc cttgagcagt ttcaatgagc
    49741 gcatagcgtt taagctctcc catttctaaa tctagtgccc gctcgtatgc aagaactttc
    49801 atcgtctcaa gagaaaaatg ttcaccgtcg atttttattt cccatctgat gacatctggg
    49861 agattcacta actcggctga ttctgctcct aaaggtcggt tatatacacc agctgcaaac
    49921 attcccctta cttgattccg atagtcttcc tcctggcttc ctctgatacc aaaaaatcca
    49981 tttccaatgg tcatctgact cgcatactta ttgatatact ctaaatcaaa ctgtttttct
    50041 tctactttca taaggtaata acttctcctg tttctgccga acgatataaa ttttccacca
    50101 gattctggat gacatatcct tgccagccat ctgcaatcat ctgagtctgg tcaccgagcg
    50161 cccgattcac aaaatgagcc atacttagtt catgtgggtc attaactggc gtggtctttt
    50221 gtaaggaaac cagctttcca tctacatctt cgaatagttc gcctggatac agattagcac
    50281 ctgcctgatc gccacaaaaa gccacattca gtttgtcttc tctgatattc aaagcaaacg
    50341 aagtattcag ttggatgatc ttgccgtttt ctaattccag tgtgccaaaa attgcatctt
    50401 ctactgtgaa tttgcttgga tcccatttcc cgaatttccc tgaatttttt ttcgtaccaa
    50461 ttttttggaa gctgtacgcc cgaacgcttt ttactttagg aaatccagta atatacatcg
    50521 ctgtatcaag catgtgaatg ccataatcga tcaaaggccc gcctccttga agttctttgt
    50581 cgataaacgt tccccagcct ggaacaccag accgacgaag cgcattcgct tctacgtaat
    50641 aaatatcccc gagaacatca agatgattct tgatcattgt tgcttcgtca gaaaaacgat
    50701 gctggaatcc ataagccaaa atctgcccgt ttttatcggc tgtctctgcc atctttcttg
    50761 cttgatcagc tgtcatagct ggtggtttct cgcacatcac tgaagcatta gcttcgaggg
    50821 cagccaatac atgttcgaag tgaaagcgat tgggtgtaca gacactcacg atatcgggag
    50881 aaatctcatt cagcatttgt gtaactgatg tatacgcatg agaaaatcct gtacgtcggc
    50941 aaaagtcttc tgctcgctgg ctgactggat caaccacagc ggccaattct aagacatctg
    51001 atcttttttg ataataagca gcatgtactt tttctgctac ttgtccagcg cctatgattg
    51061 ctactttctt catttatttc tccctccttt gcttatttac ttattgttat tctttctcta
    51121 ttctttctct aaatcattta aatgacgcgc tgtttccaga cagtttttca agtattgcaa
    51181 tgattcctga taaattttca cttcattttc tcctcgcaaa cgacattcat ataccatata
    51241 accttcatac tcattttgaa gtagcgtttg aaaatggcga gtaaaatcaa ttgcgccaga
    51301 tcctggttgg tagcgatgat tatctgctaa atggatatga cccacatact ctttttgcgt
    51361 agtcaatgct tttgaaatat catcttcttc aatattcata tgataaaaat cagcgatgat
    51421 ctgcacatgt ttcaattgat tagagtcaat gtaatgacgc gcatccgcta acaaattgat
    51481 catatggtct tggtatcggt tcaaaggctc caaataaata accgtacctg tttcttcggc
    51541 tactttatct aaataacgaa gtgattcgct gactgcttta tagtctcctt ctttgcttcg
    51601 gggtgaaacc atcggcggta atcgataagt gaacattccc caagctgctg ggataacgat
    51661 tcctttgcct ccaacctcgc ttagtgcacg caaaatctca gcaatttgac gtacaccatt
    51721 aagacgccgt tcttcgataa agtcaccgat ccacccatcg tagccgttac aagctgtcac
    51781 tactgggatc cctgtttctt tgattgcctg tttgactgtg tcgatatttt ctattaacaa
    51841 cttaccgtcg atttcgtatt cttcaaatcc acagtctttg ataaatctaa atttttctaa
    51901 aatgtctctt gggaaaaatg cttgatcttg cgtaccgaat ttcattgttc tcctcctcgg
    51961 acttgaacgc ccattttgat actttcttct gggtgctggt ctacataacg catgtaagct
    52021 tctgcgcttt ctgcaaatgg cacaactgga tcaatgattt cttcacaatc caagtaaccg
    52081 ttcatcaata attcccaaca tgtgtcctcg attcgtttac ggttccatct tgggtaatct
    52141 gggtttggtt cactagatgc tcgagcaaag acgatttttg cattattgaa atgtgcttcg
    52201 cgaccaagat taaacccagc tggaaaaggt ttagcaaagg caacataaga aatgatcccg
    52261 ccatagccga tccctcttaa agaagcttgt aatgcggcag cactgccact cgtttcaata
    52321 actgaatcta ctccacgttt atctgtcaat tcctttagac gaaaaccgac atctgctttc
    52381 ataggatcta gcgtgtaatc ggcaccgtat ttttctgcta attctctacg ctgcgctatg
    52441 ggatcgatcc caacgatggt agtagcacct gcttttttag ctaattgaat cgcaatttgc
    52501 ccgatagcgc ctaaaccgaa gattgctaca gcatcacctg ctcgaacatg tgcttcccgg
    52561 ataccaccta aagcgaattg agcaggatcg taacatactg catttttcca ttgatccaac
    52621 cgatcaagtt tacgtagttt ataattatca acaccgtttg taatcagcgt ttcacgaatg
    52681 ggtccataag tgcagactaa ctctcctttt tgatactctg tcaccaaact gcccgtttct
    52741 tcgatcgtac cgacaatcat atttcctaat tgaaattcgc caaataccac accgcgttgg
    52801 cttccttctt ctcttggcaa gaataggcgc cattcttctg aaaattcttc atcgataaat
    52861 ggacttaatc ctctaaagtc gacaatttct gttcctggtt ttggagtagc gaaaattact
    52921 cggatacgta cttcgttctt ttcgatctca cggtcttcgt aatctttgaa tccggctatt
    52981 cttggttcta atgcaactaa ttttttcatc ttttctttcc tctttctttt ctttttatcc
    53041 ttttacgccg ccttcgacta aatcaccttt aataaatcgt tcagataacg catacataat
    53101 gatgactggt aaagcggtca ccaatgaagc ggccatcatt cgtccccaaa tgtagtctgg
    53161 tgtactgaat aatgtgttca aaccgattgg taaagtaaat ttttcggagg tcgacaggaa
    53221 aatcgaagca aataaataat cattccacga aaccataaag caataaacga agacagaaat
    53281 gattccagaa atagccaatg gtataatgat ccgaataatg atctggatcc ggctaagacc
    53341 atcgatcatt gctgcttctt caatatcagt cggaatcgtg tcaaaataac tttttagcat
    53401 gaatatcgca gtaggaagtg tttgaacgac catcgtgata atcagtgctg tattggtatc
    53461 atacaaacct agaccggaaa tgattttaaa taatggaaca acgatcaaaa taccggaaaa
    53521 catataaacg gtgtaaaagc tagcattgat tttcgagcga gctttgaagc gtagttttga
    53581 caaagcgtat gccccgctga tcccaatcac tactgcagtt acggaggcta tcaaggagat
    53641 cactaaacta tttttgaaat acatgatgaa tggaaaaatc tcagcattga aaatatcctg
    53701 ataatgttca aaagtccatt ctttcggaaa aatagtttgt gtcgttgcaa ttgcttcttg
    53761 tgaatccttg aatgatgtca tcagcatgat caaaaatgga aacaaattga cagctaatag
    53821 caacaaaatc gtcgcgtaaa ataagatttt cctgctcttt ttatttttca tttcaagtcc
    53881 accttctttc gtgagagcaa gacgaccgct gcaataatga tgaacaatag aatcgatata
    53941 gctgctgctt ttccaagatc attgaacgca aaggctgtct gatacaaata aacgcctaag
    54001 atattgactt tattcgtcag tagatagaca tctgtaaaca tatagaacat ccagatagat
    54061 cgtaaaacaa tcacagttgc tagtactggt ttgattgccg gcagtgtcac gatcttgaac
    54121 ttctgccaag catttgcacc gtccatttca gctgcttcat aaagcgtttt gtcgactgtt
    54181 tgcaaaatag ccaaaaatga aataaacgca tacggatagt atctccagat agcaaacaaa
    54241 acgaccataa agaagctagc aactggctgg tcgaaccaca gcggtgcttc gttgaaaagc
    54301 tgcaacctat ctactaacag atcattgacg attccataac tattattgaa catatatttc
    54361 caagcaaaaa tcaaagaaat agatggcgta acataactta ataaaatcag tgaacgcacc
    54421 gttttcctaa atctgaactt gcggttaagc aaaatagcta cggctaatcc taaagctgta
    54481 ctgcctgcta caactaagaa tgtgtaagca actgttaaac ctaaagaacg ataaaattca
    54541 ctatcactta aaatttcaag ataattgctt aatccgataa aaacggcgtc tgagttagga
    54601 ttcagcggca tatcgaaaaa actgatctga atattggaaa gcattggaat cagcactaaa
    54661 acagctaata aaagcatgct tggtgctaaa agtcccatgg ctaattttaa gtcagaatgt
    54721 ttccttggac gattcattga aacctccccc tgataatctg ccaatagcta tctacttttt
    54781 tcgaacacca ttggcagaac ttcttgttat ttcgtatttt tttgtgcgtc agctaaagct
    54841 tgatcgacat cttcgtttcc gacagttact tggttcactg cttttccgat cacacctgag
    54901 cttgtgatat ctcccatttt cgtgaaattc ttttccccga ctagtccaaa gacttgtact
    54961 tcatcaaaag cactagcaat ctcagatggc agctcgccaa aagacttgat gacttcattt
    55021 tctttgtaac catccagttc gactacttgt ttattcactg gttgagcacc accaggagac
    55081 atcaagaccc acttttccat gtttttcggt tgagataaga aagctgtgaa tgcttcagca
    55141 gcctcttttt gtttctcgtc tagaccagaa gaaatcgtca atccagatac tgtgccatag
    55201 acagcttgat ctttttgtgt tgggatagca aaaccgatat tttctgagtt ccccgcttca
    55261 taaacagaag gcaaaatgta agttgaatag attgccattg gtgctgttcc attcatgaaa
    55321 gcatctttga tttctgtcac atcattagag cctggcatcg tgtattggga taagttttga
    55381 taaaacgaca atgcttctct catcttttcc gtatcgatcg ttacctcgcc ttcatcatcc
    55441 aaaacatttg ctccatttga caaagcaaat tgagagaacg cttgctcact cattgttcct
    55501 tcagcagtag gcatagcaat tccatattgt ttattctctt tatctgtgaa atgttgagca
    55561 atttttaaaa tatcatccca attttctggt tctgaaaaac cagcttctga taatttttct
    55621 ttgtcatacc aaataccttg aacccagccg ctaattggtg cagcaatata gctttttcca
    55681 tcttctgaac gaacaaggtt tttggctccg tcataataat tatcttctcc agcttcctcg
    55741 ataacgtttt ggactgccgt ctgatcaatc agttcatctt tatccatcac tttagcaaaa
    55801 tcctgactga cttccattac ttctggtaat ttaccggaac gagctaacgt aacgattttt
    55861 gtattgaacg ctgattcttc taccggcact tgcttgattt tgatgtctgg attttctttt
    55921 tcaaaatcag caaccagttc attgatcaca cttaatcgtt cctgttcgac agaagagtgc
    55981 atgaattgaa tcgttgtctg ttgtgattcg ttagagcttt gactttcacc acaagcagta
    56041 agaagaaatc cagtagctag cagacaggta gtaacaataa tttttttcat ttttttccac
    56101 ctcttatttt attattttca gccacatata ttcatacggc tggaatatca actttcgttc
    56161 ttgactgcaa tggataattt gtccagaaaa caggtctagg taatctcctt ttggtaaaag
    56221 ataacctgct gattgattgg aaaaattatg gataactaag actttctctt ccttcgcttc
    56281 gcgaataaaa ctgataaaag aatctgctga gtccagtaag taaatcaaac tattcggatg
    56341 gaaggctttt tctttttttc gaatagatag catctgggtc aattcaccat atactgctgt
    56401 tcttaatgga tctgtctgca actctttctc aatatctgct aacaaaaatt tttgccgatt
    56461 gatttttcga ttctctcctg ttttttctac gcctttgtaa tcatttcgac ttcccagcac
    56521 actttgaata taaattgccg gcacgcctgg taacgttacc aaaaatgaat gagcagctaa
    56581 aaagcgtttg cttctccatt ccgtcgtatc tgttggagaa cttaacgcat ctagatacgt
    56641 agcgtttatc tcatatggac tggtcgttcc atctgggttt ttcttgtagt ttactcgggc
    56701 accctctttc ttcagctgtt ccactaattc aaggatcgtt ttttccggca gaatacctcg
    56761 taccggattc aatccgatac cgtcatggga ggctaaaaaa ttaaaaaaag ttgttttttt
    56821 cgatgcgaaa tcgatggttt ttaaccattc tttcaactta cttgtattac ccgaacgaat
    56881 cgcttgaagg gtcaaaggtg gtagcgaaaa ctgatagacc atctgtgctt cattctcgcc
    56941 attcccaaaa taactgatat tatctttgtg tggcacattt gtctcagtga tcaataccgt
    57001 tcctggagct gcttcatcag cgattgcacg gaataattgg atgattttat gcgtttctgg
    57061 caggtgtata caagaagttc ctagttcttt ccataaaaat cccacagcgt ccaagcgaat
    57121 aaatgaagcg cctttttcta agtaaaacaa aagaatatcg atcattttca ataaaacttc
    57181 tggattttta aaattcaagt ctacttgatc ttcgctaaaa gtcgtccata cgtgtttttc
    57241 tttcccgttt ttgtcaatga acgttgtaag taacgggctg gtccttggtc tagtcacgct
    57301 gcttgtatct gtatccagtg gcaaatcaat aaaaaaatct ttgtacgtat cattcaagtt
    57361 taaatattcc tgaaaccaag tactttcggc agacatatga ttgcagacaa agtcgaacat
    57421 taaccgtgtt tcgcttctca tttcttctat atcttcccat gtgcccaaac ggtcgttgat
    57481 tgcctgataa tttacaacgg agaaaccatc atcagatgta tatgggaaaa atggcaagaa
    57541 atgtacaact ctaaatgtat ctgccaaata cttttgataa aatttcttaa atgtacgcaa
    57601 agttggttgc tgctcttcaa aaaattgatc cccataagta atcaagaaaa tatcttcttc
    57661 gtcccaatgc agtttgcctg cctggccttt cttctgctga taaacactga ctttttgttc
    57721 aatcatagag gcggttttct cagacaaatc tgagtcgcga taaatcgctt gtaaaagttt
    57781 tgtatacatc ggattcccct ttcttttttg ggagcgttcc caacgatttg atcatattat
    57841 ggaaaacgct tactgtcaat agcatttttt taaataattt tgatatacac aaaaatacaa
    57901 ataagaaagc ttatgtatca ataattaata gcttcttaaa aaaatatggt ctctcatgat
    57961 catgcaagct attcctaaat tttcaaaatc atagacaaaa aagaatgtct attgtactat
    58021 ggaattattc taaaacgctc ccaaaaagga ggtgcatata aaattgaaac ctactattta
    58081 tgacattgcg aaaaaagcta atgtctcaaa atcaactgtc tccagagtat taaataacca
    58141 gccaaatatc tctgataaag caaaagcaag tgtacttcaa gcaatcaaag aattgaatta
    58201 tgaaccgagc aaaattgcaa gaggactgtc aggaaatggt tttgacgcga ttctagcatt
    58261 atctcatcgt acttctcata cgacctatgg caatcctttt ttttcagatg ttattcaatc
    58321 catttctgcc gtttctgaac aaaataactt cgacttgatt ctacaaacgg caaaaacacc
    58381 agaagaagag ctagaaaaat gcgcgaaaaa gatccaagaa aaaatgatcc gaggaattat
    58441 tattttaagc tctacgatgg atgaaacact tctttttgaa ttggatcaat acaatattcc
    58501 tattgtggta atcggaaaag tcggaaacga ctacacgaac atctactcag tggacacgga
    58561 taatttccag gatagttacg atttggtgga aacactgatc aagaatggac accgtcatat
    58621 cggctgtctc catgctccga cagaagttta tgtatccaat gatcgtctca atggttaccg
    58681 tcaatgctta tttgatcacc acctagatat ccgtaatgaa tggattatag acggcggctt
    58741 tcgcttagaa gatagcatgg cagcaatgaa tgatttaatg aagctacgag aaagaccaac
    58801 tgcgattttt tctaccgatg cattaaaatc attgagtatt tacaaagtgg cagaacaatc
    58861 tggaaagcag atacctgatg atctttcgat cgcaggattc agtgatccct tattgtcctc
    58921 cctattttcg ccacagttga ctcggataga cattccgaca aatcagttag gaatcaaagc
    58981 cacagaactt ttattccaac taatccacca ccaataccct gaagaaaaaa gaatcattct
    59041 ttcaaccgag attactctca cagattcgat ccaacaacaa gaaatgtaga acagaattat
    59101 aaaagaacag aaacactgag gataagtcag ttactctgtt cttttttcaa tcactcatcc
    59161 ctcgttaccc cctcccggta ttttagcgaa tttttcttat tttccatctg ttttagatag
    59221 ctgtggataa ctataatgtt tgtgttaaac tattttttcc acagggaaga aaaaactatt
    59281 tttaaccacg ttgtgtataa gtttttatag ttcgtttttt taaacacatt tacccttatt
    59341 tcaatccatg ttatttgggg atacttatct ctaaaacata aatagaataa cagacatgtc
    59401 tactggtttt gttttattcg aggaattatt caataatagc tagcaaaata ttaaaaataa
    59461 ccgctctatc ttcccatcaa tttattttgc attcaaaaaa tgatctatct ttacttttgt
    59521 tgattgactt ctcttggaag atgatcgttc cgatacctta attggatacg aaccgatgtt
    59581 gttaagatcc tttcccactt ttcttctagt tagacaaatt attttagaca aaccaaaaaa
    59641 gaggttgtga caataatttg tcacaacctc ttttttaaaa tatctatttt gtttgattgt
    59701 tcattgcgtc ttctgcagcc atttgcgctt caatatctga aatactgtag acattttcgc
    59761 ttgctacacc gacttctttt ggttccatgt cacgataacg ttgcatacca gtaccagctg
    59821 ggatgatctt acctataata acattttctt tcaaaccaag aagaggatct ttcttaccgc
    59881 ggatcgcagc atccgtcaag acacgagttg tttcttggaa tgatgcagca gataagaaac
    59941 tatttgtttc taatgatgct tttgtgatac ctagtaagac aggtcgagaa gttgcaggaa
    60001 cgcctcctga gactagcgta ttgtagtttt gatctttaaa gtctgcgatg tctaataatg
    60061 tacctggtaa gatatctgta tcacctggat ccattacacg aactttacgc agcatttgac
    60121 gaaccattac ttcgatatgc ttgtcgccga tttctacccc ttgcatacgg taaacacgtt
    60181 gtacttcacg aagcaagtag ttttcaacag ataatacatc gcgaacttgc aacaattgtt
    60241 ttggatcgat tgatccttct gtcaatggtg caccacggtg gatcatatcg ccttctgcta
    60301 ctttcatacg tgctgtataa ggaacagtat acgtacgtgt atctgttttt cctttgattg
    60361 ttacttcttt ggtacgtgtt gcaggatctt ctgagatatc gatgacatcc cctgttactt
    60421 ctgtgatcac tgcttgccct ttcggattac gtgcttcaaa gatttcttgg acacgaggaa
    60481 gaccttgagt gatatcgtct ccggcaaccc cacctgtatg gaatgtacgc atcgtcaact
    60541 gagtaccagg ttcaccgatt gattgagcgg cgatcgtacc aactgcttct ccgacttcaa
    60601 cgtcagagcc agttgcaagg ttgcgtccgt aacaatgttt gcagacacca tgttttgtat
    60661 tacatgtgaa gacagaacgg attgtcactg tttcgacacc tgcatcaacg atttgttttg
    60721 cgatgtcttc ggaaatcaat tggtttcctg caatgatcaa ttcatttgtt tcaggatgac
    60781 gtacttcttt acgggtgtaa cgtcccacta aacgatcttc taatgattcg atgatttcat
    60841 ttccctcgcg gatggcttgg atttcaagac ctcggtcagt accgcaatct tcttcacgga
    60901 tgattacatc ttgggccacg tcaaccagac gacgagtcaa gtaacctgaa tcggcagtct
    60961 tcaaggctgt atcggtcatc cctttacgag ccccgtgagt tgagataaac atttccaaga
    61021 cggatagtcc ttcacggaag ttcgaaatga ttggcaattc catgattcga ccattaggag
    61081 cggccatcaa accacgcatt ccggcaagct gtgtaaagtt ggaaatgtta ccacgagctc
    61141 cagaatcaga catcatgaag attggatttt tcgcttccaa accttccatc agtttttgtt
    61201 ggatgctgtc ttttgcagca ttccaaacag caatgacacg ttcataacgt tcgtcatctg
    61261 tgatcagacc acgacggaat tgttttgtaa tagtttcaac ttgtttatgg gcattttcaa
    61321 tgatttcttg tttttcattc agtacactga tgtcagcgat ccctactgtg ataccggcat
    61381 gtgtcgaatg tttgtaccct aagtctttca tacggtcaag catcttagaa gtttctttta
    61441 ctttgaatcg tttgaagact tctgcgatga tgtttcctaa gtttttcttc ttgaacggta
    61501 atactaattc ttgctctttg atatgtgcag gaatatcagt accagcttca acaaagtatt
    61561 tgtccggtgt ttggacggtc aagttgaagt ctgttggttc attcagataa gggaattcag
    61621 gaggcatgat ctcgttgaag atgatcttac caactgttgt gatcatcgta cgttcttttt
    61681 gccattcagt aaatggtttt tcacctaatg agttagggtt cacaccgata cgtgaatgta
    61741 aatgaacata tccgttgcgc catgcgataa cggcttcgtt ttgatctctg aagaccattc
    61801 cttcgccttc gcgtccttct tcttccattg tcaagtagta gttacctaga accatatctt
    61861 gagaaggagt aacaactggt ttaccatctt tagggttcaa gatgttttga gcagctaaca
    61921 tcaacatacg tgcttctgct tgtgcttctt cattcaatgg aacgtggaca gccatttggt
    61981 ctccatcgaa atcggcatta taagcttcac atacaagtgg atgcaaacgg attgcgcgtc
    62041 cttgtactaa aactggttcg aatgcttgga taccaagtcg gtgaagcgta ggtgcccggt
    62101 tcagcaatac tgggtgttcc ttgattacgt cttctaaaac atcccatact tcgtcttctt
    62161 gacgttcgat tttacgtttc gcatttttga tgtttgaagc tagttcgcgt tgaacaagct
    62221 cacgcatcac gaatggtttg aataattcaa tggccatttc ttttggaagt ccacattggt
    62281 acatcttcaa gaaaggtcca acaacgataa cggaacgacc tgagtagtcg acacgtttac
    62341 ctagcaagtt ttgacggaaa cgaccttgtt tccctttcaa catatgagaa agagatttca
    62401 atgggcggtt acctggtcca gtaactggac gtccgcgacg accgttatcg atcaatgcat
    62461 ctactgcttc ttgcagcata cgtttttcat tttgaacgat gattccaggt gcattcaagt
    62521 ctaacaaacg tttcaaacgg ttattacggt tgattacacg acggtaaaga tcattcaagt
    62581 cacttgttgc aaaacgtcca ccttctaatt gaaccattgg gcgtaaatct ggtggaataa
    62641 cagggataac gtccataacc atccagcttg gttgatttcc tgaagcgcgg aatgcttcta
    62701 aaatatccaa acggcggatt gcacgtgtac gtttttgtcc ttgtgcagat ttcaattctt
    62761 ctttcaattc ggctgcttct gcatctagat caacattatc aagtaattgt ttaatcgctt
    62821 ctgcacccat agcagcttgg aattcttgtc catattgttc acgtttttcg cgatattcgc
    62881 gttctgtcaa caattgtttt ttctctaaat tcgtatttcc tggttcgatg actacatatg
    62941 aagcaaaata aatgatttct tccaaagcgc gtgggctcat gtctaataca agacccatac
    63001 gtgaaggaat ccctttaaag taccagatat gtgaaacagg agctgctaat tcaatatgtc
    63061 ccatgcgttc acggcgaact ttcgaacgag taacttccac tccgcatcga tcacaaacga
    63121 ttcctttata acggatacgt ttgtattttc cgcaggcaca ttcccagtct tttgtaggac
    63181 caaaaatccg ctcacagaac aacccttcgc gttcaggttt taaggtacga tagttaatcg
    63241 tctcaggttt ttttacttca ccgtaagacc agcttctgat tttttcggga gaagccaaac
    63301 ctatttgcat actttcgaat ttatttacat cgatcaaaag gggttccctc catttcattt
    63361 aatggcaaac cgcaagacgg ctgatcttcg accgccttgc agctcataga ccggattagt
    63421 ctaaattatc ttctgcggtt tcaaagtttt ggatgacatc gtctttttca tcttccactt
    63481 gttcagcagc tttcttttct aattctttgg cagtttgctg ttcggcaaat tttgtcaaag
    63541 catcaacagt gatcaaatcg tcgtcttcat cgtccatgtc gcgaagttcg atctctgttt
    63601 cttcgatatc caagacacgc atgtccagac ctagtgattg caattctttc accaatacgc
    63661 ggaatgattc cggtacacct ggttttggaa ttggttcacc cttgacgatt gcttcgtatg
    63721 ttttcacacg tccgactacg tcatctgatt tgtatgtcaa gatttcttgt aaagtataag
    63781 ccgcaccgta agcttccagt gcccatactt ccatttcacc aaaacgttgt ccaccaaatt
    63841 gagctttacc tcccaatggt tgttgtgtaa ccaatgagta aggtccgatt gaacgtgcat
    63901 gcaatttgtc atcgaccatg tgagcaagtt tgatcatgta catcacaccg acagacacac
    63961 gtccatcaaa tggttcacct gtacgtccgt cgtacagaac agttttcgca tcgctggcca
    64021 taccggcttc acgaactgtt tcccatacgt cttcatcact tgcaccatca aatactggcg
    64081 ttgctacgtg gatacctaac tgacgtgcag ccatacccaa gtgtaattcc aatacttgcc
    64141 cgatgttcat acgtgaaggc acccctaaag gattcagcat gatatcgatt ggtgttccat
    64201 caggtaggaa tggcatatct tcttccggca taatacggga tacaacccct ttatttccgt
    64261 gacgaccggc cattttatcc ccttcatgga ttttacgttt ttgaacgata taaacacgaa
    64321 ctaacatgtt tacgcctggt gacaattcat ctccagcttc acgagtaaag attttcacat
    64381 cgtgaacgat accgccgccg ccatgtggta cacgtaatga tgtatcgcgg acttcacgag
    64441 ctttttcgcc aaagatcgca tgcaatagac gttcttctgc agataattct gttacccctt
    64501 ttggcgtgac tttccctaca agcaaatcgc catcttggac ttctgcacca atacggatga
    64561 tacccatttc gtctaaatct tttaatgcgt cttccccgac attagggatt tcgcgtgtga
    64621 tttcttcagg tcctaatttt gtatcgcggg cttctgattc atattcttca atatggatag
    64681 aagtgtatac gtcatctttt accaaacgac ggctcatgat gatcgcatct tcatagttgt
    64741 acccttccca agtcatgaaa ccaactaaaa cgttttggcc tagagccatt tcgccttgtt
    64801 ccatagatgg tccgtctgcc agagtatccc ctttttcgac tttctcaccc aaatgaacga
    64861 ttggacgttg gttgtagctt gttccggagt ttgaacgacg gaattttgtt acatcgtatt
    64921 tatctaatgc accgttgtcg cggcgtacgc ggatttcaga agcatcaacg tattcaacga
    64981 caccatcatg tttacataac aaagcagctc ctgagtcatg cgctgatttg tattccatac
    65041 cagtaccaac ccatggtgct tgaggattga tcaacggcac tgcttgacgc tgcatgttgg
    65101 cacccatcaa ggcacggttg gagtcatcgt tttccaagaa aggaatacat gctgtcgcaa
    65161 cggcaactac ttgtttaggt gatacgtcca tgtagtctac tttatcaata gatacttcta
    65221 agttttcact ttgagcacga gccataacaa cgtcttgagc aaatgttcca tcttcattca
    65281 atgggctgtt tgcttgggct acgatgtaat ggtcttcgat atcagctgtc aagtagtcga
    65341 tttggtcagt aacacgacct gtttcacggt ctacacgacg ataaggtgtt tcgataaatc
    65401 cgaatttatt tactttcgca taactggaca aactattgat caacccgatg tttgggcctt
    65461 caggagtttc gatcggacac atacggccat agtgggagta gtgaacgtca cgaacttcat
    65521 aaccggcgcg gtcacgagtc aatccgccag gtcctaaggc gaaaagacga cgtttgtgtg
    65581 tcaattcgcc aagagggttt gtttgatcca tgaactgtga caactgagaa gaaccaaaga
    65641 attctttgat acttgccaca actggacgga tattgatcaa ttgttgaggt gtcaatgttt
    65701 cagtatcttg gatcgacatt ctttcacgaa ccacacgttc catacgtgct agcccgatac
    65761 ggaattggtt ttgtaaaagt tcaccgactg aacggatacg acgatttcct aagtggtcga
    65821 tatcatcgac attgccgata ccttccatca agttcaagaa atagctcatt gaagcaatga
    65881 tgtcggctgg acgaaccgtt tttacagctg cttctggata gccgtttccg atcacgttta
    65941 cttcacgttc agggtctctt ggtgaaaata ctttgatgac ttggacagtc attggatctg
    66001 tgaccacacc gtcttctgat ggatagtaag tcactgaatt taggccatta tcaatgaaag
    66061 gagctagtgt ttccatgact tggtgagtca gaactgttcc tttttcaacg atgatctcgc
    66121 ctgtttctgg atcaactaat gtttcagcta atgtcagatt caatagacgt gttttcaaat
    66181 ctaatttttt gtttactttg taacgaccaa cgtttgctaa gtcgtaacgt tttggatcga
    66241 agaaacgagc attcagcaag ttacgtgagc tgtctgctgt ttttggttcg cctggacgca
    66301 aacgttcgta aacgtctttc aaaccttctt ctgttcttga gtcgcttgcg tttttatgca
    66361 agtctttttc gactgtattg cgtaatgttt cgctgtcgcc gaagatttca aagatcgtat
    66421 catcggaacc aaatcctaac gcacgaacta atacggttaa aggaatctta cgtgtacggt
    66481 cgatacgtac ataagagatg tcttttgcat cagtttccat ttctagccaa gctccacggt
    66541 tagggataac agtagaaccg aatccttctt ttccgttttt gtcgactttt ccatggaaat
    66601 agacacctgg tgaacggact aactgagaaa cgattactcg ctctgccccg ttgatgatga
    66661 atgttccttg ttctgtcatt aatgggaaat caccgaagaa tacttcttgt gctttgattt
    66721 cgccagtctc gcggtttgtc aaacgcaatg ttacatgtaa tggtgcagag tagtttgcat
    66781 catgcgcacg agcttctgct actgtatact ttggttcttt caattcataa tctacaaatt
    66841 ccaaagatag attgccattg aagtcatcga ttggcaaaat gtcttcaaac atttctctaa
    66901 gtccctcatc taagaaccat tggtaagagt ctgtttgaat ttcgatcaaa tttggtaatt
    66961 ccaacacttc actgattctt gcgaaacttc tacgttcgcg atgttttccg tattttacta
    67021 cgtgtccagc caagctcttc acccctctaa aatgtcattc aaaaagacta cccgatcaat
    67081 tgttacaata atatttcaaa tattattttt aggtaacaac agacattttt tgcggctttt
    67141 aggcaaaaaa aaaccaaaaa tagaacattc tcttgaaacc ttacttcgtg agcttctact
    67201 tttgtttcct tatattaaag ccgaaacgga caatatttcg tttctgcctt ttcttcatca
    67261 gatagttttt gcaacttcat atactacact tattttctat aaaagtcaac acttcctggc
    67321 gtttcttctg ctttttcgca acattttctt aatgttttca attttatgtt ttcaattatc
    67381 tgacaattct taattgacag acctttttat ctcggttata ctttagaaaa ttcattttgt
    67441 ggaggaactt ctatgcgaac caacatcaac caaatcgcac caacacaact gaataacttt
    67501 tactttagct actttagata ggtttgtatt catcatgatg gatacaaacg ttaaacgaca
    67561 gtttgtatct atgatggcta aagaactttg tattgcagca aaaagccacg tagacaaaat
    67621 gctaagtggc tgagcagtga aaatacaaag taaaagtatc aagcattcta ctttttcaat
    67681 ttattttccg acttttcaat ccatttggac attttgtctg aatggatttt ttgtttccca
    67741 aaattaagga ggaaaaagaa atgaaaaaaa atataatcat cggattaggc gctgccctgc
    67801 tactagcttt aggaggttgc gcacaaaaag acaattccgc agaggcatca gatggacaaa
    67861 aaacaattgg cgtattgcaa cttgtacaac ataactcgtt agatgctgcc tataaaggat
    67921 tcaaagaagg attagcagaa gaagggtata aagaaggcga taatctaaca atcgattatc
    67981 aaaatgccca aaacaatcaa gacaacctga aaagtatgag tgagaaactc gtcaaagaag
    68041 atcctgattt gctacttgga atcgccactc cagcagcaca atctttatta aatgaaacaa
    68101 ccactatccc gatgactgtc acagcggtca cagacttgga acaagcccat ttagtcacat
    68161 ccaatgaaaa acctggcggc aatgtgactg gcacgacaga tatggtgcca atcgaaaaac
    68221 aaatcggctt actgttaaat atcgtgccag acgccaaaac aatcggcatc atgtataaca
    68281 acggtgaagc aaactctaag atccaagctg atttggcaga aaaagaattg aaaaaagcgg
    68341 gcgtcaaagt caaagtactg acagcaaatt ccacaaatga tgtccaacaa gtgacgaaaa
    68401 gtctagctaa agatgtagat ggaatctata ttcctactga taacacgttc gcaagtgcgg
    68461 caagtgttgt cggtgaagtc gcaaaagaaa caaaaacacc tgtcgttgct ggcgcagttg
    68521 atcaagtcaa agacggcggt ctagcaacag taggaatcga ctacgaaagc ttgggcaaac
    68581 aaacagggat catggcagca aaaatcttag acggcaagaa tccaagtgaa cttcctgtcg
    68641 aaacagcgaa tgatttggaa ctgtatgtca ataaagacat ggccaaagca ttaggcatca
    68701 atccagacag catcaaagaa gctgaataaa acacaggagg attctcatga caaatttgct
    68761 ctctcttttc ttatcatctg catcgcaagg ggtcttatgg gccctacttg cgattggtgt
    68821 atacgtcact ttccgtatct tggacattgc cgacttgact gctgaaggaa gctttccttt
    68881 aggtgcaggg atcgcggcag taagtattac aaatggctat catccattga cagcttgtct
    68941 tctaggcttt ttagggagtg cggcagcagg gcttgtttcc ggactgcttc acacaaaatt
    69001 gaaaattccc gcccttcttg cagggatcat caccatgact ggtttatatt ctgtcacatc
    69061 ccgtgtgatg ggtgcgccga acatctcttt attgggtcag ccaacgatct ttcattgggt
    69121 cgagtcattc ggcataacaa aagacaacgc tgtactgatc gtcggtctgc tttttgcttt
    69181 gatcgttgta tgtttacttg ttttgttctt acgtacagaa acaggacttg ctattcgtgc
    69241 aactggcgat aatctggcaa tgagcgaagc aaacgggatc aacacagata atatgaagat
    69301 catcggttat atgatttcta atggatgcat tgctctttct ggctccttgc ttgcgcaaaa
    69361 caacggcttt gctgatttaa attctggtat tggaacgatc gtaattggac ttgcttctat
    69421 tatcatcgca gaagttttgt tacgtaacca gccactattt ctccgtctct tgactgtcgt
    69481 tttaggtgcg gtcatttatc gttttatttt agcgttagtc ttcgaactga atgttgaacc
    69541 aagtgattcg aaacttgctt ctgctttcgt gctagtgatc tgtctttctt tcccgcagat
    69601 ccagcaaaaa ttccatttac ctcaaaaaaa gaaaggcggt agtgtcaaat gaatgacgtc
    69661 ttaacattgg aaaatctcca tcataccttt gaaaaaggaa cgatcaacga aaatcatgtc
    69721 ctgaaaggca ttaatctttc cttagatccc ggcgacttcg tgacgatcat cggtggaaat
    69781 ggggctggta aatctacttt gctgaacagc atcgccggta cattttctgt cgatcagggt
    69841 caaattttat tgaatggaaa aaatatcacg aaaaaatctg ttgtcgaacg ttcgaaatcc
    69901 atcagtcgcg tattccaaga tcctaaacta gggacagccg ttcgtttaac ggtagaagaa
    69961 aatcttgctc ttgctatgaa acgaggaaaa aaacgcggct tcttccgtgg tgtcaaacca
    70021 caagaccgaa catttttcaa agaccagctg gttcggctaa atttggggtt ggaaaatcgt
    70081 ttatcctcag aaatcggttt gctgtctgga ggacaacgtc aagctattac gttattgatg
    70141 gccacattac agcgtccaga actgatctta ttagatgaac acactgcagc gcttgaccct
    70201 gctacttcca aaacggtgat ggaattgaca gaaaagctga tcactgagca gaatctcact
    70261 gcttttatgg tcactcatga catggaagac gcgatccgct atgggagtcg actgatcatg
    70321 ctgcatcaag gaaggatcgt cgtagatatc cagcaagagg aaaaacagca gctcacagtg
    70381 ccccaattat tagcgttgtt caaacaaaac agcggcacgg cattaaaaga cgatcaagta
    70441 cttttatctt cataatcaga aagaggatgg gacaaaaaat gaacgcccac cctcttcttt
    70501 tttctctttc cttctttcgt ttttgcttta tgtatcaacc gttgtttctt cgaaaactat
    70561 tttgttctct ccttcttcct gatagaatgg atgggaaagg agcttgatgc catgacaacg
    70621 aaagacaagg tacttcaatt attgaaaaag acaccagatt ttctttccgg agaaaagttg
    70681 gcacagcaac tggaagtttc ccggacaagt atttggaaag ccatcaaaga attggaaaag
    70741 gcaggctatc gttttgagca cgggcctaca gggtatcgtt acctgccctc tgacgtacta
    70801 gatgcaaaag aaatccagca agagctacgg tcgtttattc ctgatttgaa agtacaaacg
    70861 atgttgactt ctgaatctac gatgaaagat gccaaactgg cagcagctca aggagattct
    70921 gtttcgaagt tatttgttgc tgatacacaa gaacaagctc gtggacgttt tggacggcct
    70981 tttttcgctg aacctggacg aggaatctac atgagtctct tgctccatcc agacaaacgg
    71041 tttgatgaat tgcctcaata tacgatcatc gcagccagtg cctgtgtgaa agccattgaa
    71101 tctgtaaccg gtcgttctgc ttcgatcaaa tgggtcaatg atatctacat ggatggaaaa
    71161 aaagtctgtg ggattttatc tgaagcagtc agtgatatgg aaagcggcag gatcagtcat
    71221 atcatcattg ggatcgggct taatttttct gttcctcaaa atcattttcc agctgatctc
    71281 caagaaaaag ccatctctgt ctttcccgac ggacaagcta gtgtcacaag gaatcagcta
    71341 atcagcaaaa tctggcaaga attgttcact tatctttctc acccagaaaa agcgttggac
    71401 ttctataaag aaaaatcatt cgtattggga aaaaccgtgt cgttcaatca aaaaggaacg
    71461 acttatgtcg gtcttgcaaa agaaatcggt gatcatggcg aactgatcgt ccaaacaaat
    71521 gaacagaaga tgagtttgtc ttctggcgaa atcagtctca catctatccg tacgcaataa
    71581 ttatcagatt tcacaaaagg acacctgatc tcatacagtg tccttttttc tgaattctct
    71641 tcaaaagact ctccttattc tatcagctga cagtttctct atcctctaga aaaaggtatt
    71701 ctaaaaatat ctataaagca tggtacactt tctttaaatg aatcaatgca aaaaacaaga
    71761 gagtcatcag tttacacgat caaaagagat agcaggccgc ttcctttttc aatcttatag
    71821 atagaccatg ggtaacgata aaaacaaaaa agaacttgcg acttattttg ccgtaagttc
    71881 ttttttagct agtgccttaa tctcttaatc ccaacaaacg tctcgcatag atcacctgac
    71941 cagagtgcat agcagcatca tcaataatag aaacgagacg cattcctcgt gtgactggtg
    72001 gtgtccagtt ctcgtcaatt acttcatcta gctcggaagg ttccagcctt cttaagtaag
    72061 aaatagcaaa atcagcagct cctcgcaagt atcctagcag atcttctatt tgattagctt
    72121 ggatctgctt tgcttgttcc agactatgct tccaatcttg ttcgttatct gctatcgtca
    72181 tcggaaaccg gctttcccag tcttgactat gccaaattgg agaagttcct gctaaatcag
    72241 caatctggaa atctaattct cgagcggtat gccaagccag ccaagtcatt gatttgatct
    72301 gcggggctct atcttccact ggaaaacgat tggcctcctc aatagagacg ccttcaaaca
    72361 aacgttcaaa ccgatcgtat gcccgatcca cactctcgca tagcatatct aaataatcca
    72421 tttattttcc tcctttttat ttatcctact tactttttcc taattctagg atacctactt
    72481 atatgttact acacaccctt attttttaca ctttaacagt caccatcatc aatagtttgg
    72541 agattgaaag aaaaagatag tgtcgaacta tcaattgaac aagaagcaac aatatgaacg
    72601 tttcattaat attctttaaa taaacaatga tttttcaaac gaacagttta agactaggag
    72661 aaaaagagta taataggaaa atgtttgaaa ggaaaggaag gggaaaaatg aaaaaaaggg
    72721 caagtttact agtcctagtt gctttgttgt tcaatatctt ttcgtatggt gtggccgttt
    72781 cagcggaaac atacattcct aaagaccctg ggaatattta taatgatcta actggtaact
    72841 atggcttgtt aggaattgct agtcaattcc acgtatttgc taaaaataag acaactgtga
    72901 atgcacatac agacggaaat atagcaacac atgaacttga tgcaaaaaat aattttggta
    72961 cagagcttca tgaaggttta ttgaaccaag aaataaatta tatacaaaaa actgattctt
    73021 tcgctaattc ttcaggcata cctacaggta gcacaagaat gaataaattt gtcgttggca
    73081 gtaacgtgga tgtagcactt caagatggtc atcctacagt caatggatcc aggcttgatc
    73141 acttaactcc agatgatttt tataaagatc gtgctgggca tgaatatatt gatttcgagc
    73201 aggaatttgc taaattgaat gtagcagcaa atgatcttgc aacgatcact ccagctaaaa
    73261 catatactgc tgcagatttt ccagacatga acaatcggac aatcgattta actgatttat
    73321 cagataccgg gtttttattg gtaaatatcg atgcagaagt gttaacgatg aatacgccac
    73381 ttcaaatcat taatccaaat gatcaagtag ttgtatttaa tgtcatcaac agttcttctg
    73441 cattgaacgt acagtcacca atcaaataca atgatcgttc aaatcatgaa acagaagatt
    73501 tttcggatgc gaatatctct tggaattttg gaaatgagat gactgatttg acaatcagtg
    73561 ctccttttca aggaacaatc cttgcgccta atgctactat ccgcattact caaaaccaag
    73621 acggaacgat tataggaaca aatgtgattt tagatgcagc taccaatcgt tgggatccta
    73681 acgaaatatt tatcagcgac aatggtacag atactacaga cacaagcgac agtacagata
    73741 catctaccac aagtgatagc tcagattcat ca
//
LOCUS       DAZULR010000009        72965 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.009, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000009 DAZULR010000000
VERSION     DAZULR010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 72965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72965
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.009"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(305..1930)
                     /gene="groL"
                     /locus_tag="ACG8ZV_000643"
     CDS             complement(305..1930)
                     /gene="groL"
                     /locus_tag="ACG8ZV_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HFS4996012.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDATIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
     gene            complement(1981..2265)
                     /gene="groES"
                     /locus_tag="ACG8ZV_000644"
     CDS             complement(1981..2265)
                     /gene="groES"
                     /locus_tag="ACG8ZV_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HFS4996013.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            2490..3152
                     /locus_tag="ACG8ZV_000645"
     CDS             2490..3152
                     /locus_tag="ACG8ZV_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HFS4996014.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            complement(3228..4520)
                     /locus_tag="ACG8ZV_000646"
     CDS             complement(3228..4520)
                     /locus_tag="ACG8ZV_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFS4996015.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQHLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            4690..5319
                     /locus_tag="ACG8ZV_000647"
     CDS             4690..5319
                     /locus_tag="ACG8ZV_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFS4996016.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAASDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            complement(5422..6231)
                     /locus_tag="ACG8ZV_000648"
     CDS             complement(5422..6231)
                     /locus_tag="ACG8ZV_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFS4996017.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(6286..7155)
                     /locus_tag="ACG8ZV_000649"
     CDS             complement(6286..7155)
                     /locus_tag="ACG8ZV_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HFS4996018.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            complement(7156..8472)
                     /gene="yycH"
                     /locus_tag="ACG8ZV_000650"
     CDS             complement(7156..8472)
                     /gene="yycH"
                     /locus_tag="ACG8ZV_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system activity regulator YycH"
                     /protein_id="HFS4996019.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            complement(8469..10304)
                     /gene="walK"
                     /locus_tag="ACG8ZV_000651"
     CDS             complement(8469..10304)
                     /gene="walK"
                     /locus_tag="ACG8ZV_000651"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HFS4996020.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVILSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            complement(10309..11013)
                     /gene="yycF"
                     /locus_tag="ACG8ZV_000652"
     CDS             complement(10309..11013)
                     /gene="yycF"
                     /locus_tag="ACG8ZV_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator YycF"
                     /protein_id="HFS4996021.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            complement(11203..12063)
                     /locus_tag="ACG8ZV_000653"
     CDS             complement(11203..12063)
                     /locus_tag="ACG8ZV_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFS4996022.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITPEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            complement(12050..12619)
                     /locus_tag="ACG8ZV_000654"
     CDS             complement(12050..12619)
                     /locus_tag="ACG8ZV_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HFS4996023.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            13000..13072
                     /locus_tag="ACG8ZV_000655"
     tRNA            13000..13072
                     /locus_tag="ACG8ZV_000655"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13033..13035,aa:Lys,seq:ctt)
     gene            complement(13568..13954)
                     /locus_tag="ACG8ZV_000656"
     CDS             complement(13568..13954)
                     /locus_tag="ACG8ZV_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HFS4996024.1"
                     /translation="MNKRKTEFILILISGITGILCSLLALMGGMFLSSIDSTTLNTTE
                     LTSKDIDMLVNLSGNVVLFGGITLVFSIMIFIIGFLVRKNQKTVVYGISLLILSIIPF
                     FLLTLLWVIPGVLGIIAGLMLLIRKS"
     gene            complement(13951..14472)
                     /locus_tag="ACG8ZV_000657"
     CDS             complement(13951..14472)
                     /locus_tag="ACG8ZV_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HFS4996025.1"
                     /translation="MNKKSGIETLPNYVFAGFWLRFFAFLIDLICISIITHATIGLFY
                     KIMGLESDKSIITFYGIASLAIYLTYFVLLTKLNSGQTIGKMIFGIRVVSFEEKELSW
                     QTIFIRECICRFILKNFVFQIGYLVAAFTPKKQHIGDYFSNTSVVVIRSLEAINYGQK
                     ISNSKTLNLERIK"
     gene            complement(14474..15508)
                     /gene="sppA"
                     /locus_tag="ACG8ZV_000658"
     CDS             complement(14474..15508)
                     /gene="sppA"
                     /locus_tag="ACG8ZV_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HFS4996026.1"
                     /translation="MNKRRWIAVGVACGLLLLSIIVALIPGKDKEEASNTTLTGINKI
                     FYGSNEITEETLEEGASNKKIVKLSVNGVIADTGESNLFSREQYNHQNFLTQLKKIQE
                     DKAVKGVLLEVNSPGGGIYESAEIAKEMAKIKKLDIPIYTAFKNTAASGGYYISAGSD
                     KIFATEETTTGSIGVIISGLNYSGLLEKLGVTDATYKSGALKDMMSPQHKPSEEENKV
                     IQEFVMSAYDRFVNVVAKGRNMDTNAVKELADGRIYDGNQAVENGLVDQIGYSEDALD
                     SLKKEKKLTDATVIEYKNDTTGFASSWLGNKIAEWQGLKATTSDRVISVFEKLGFSDT
                     PKPMYYYGGL"
     gene            complement(15541..16956)
                     /locus_tag="ACG8ZV_000659"
     CDS             complement(15541..16956)
                     /locus_tag="ACG8ZV_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HFS4996027.1"
                     /translation="MVSIKNYGKSRRGKQFMQNNNWFEHSSIYTKQHHSFYRWVLYPV
                     ILFLCIIGLFLTFAKKEVVIRTTAQLNPEKIEKLQVPLEAKIMENFLKENQFVHKDDV
                     LVRLDCSLIENEKAQIEQENQRITQQIKMAQLFIESISKGKNLFSTDDSFGYSNQLKS
                     MLSEKESLRYALKQSELNDQKQLEVYEKTKRQLEKQIESSDSKLQEWQQVQVAWSNNQ
                     SLKDFSKEMMANYENWQEQLNNVSDDQKNQVKLTISASINEQIEQLKKEVEQYQSEKA
                     KLVKPTTSENDRISQTEKGKQELEQAITTVKQTVTELNEKQEKNQSVIKSLDDQLSKG
                     ILKAPVSGTVHLNEETKGQAELAKGTVLAEIYPIHEKSKMKFTALLPANESTYIKEGM
                     KVHFKLDQKGGAPITIDGTLDEISENSTATEKGVFYAVKGTLKTTQSFPFRYGLTGEL
                     SLIVGEKTYWQQIVDVFLNKK"
     gene            complement(16925..19078)
                     /locus_tag="ACG8ZV_000660"
     CDS             complement(16925..19078)
                     /locus_tag="ACG8ZV_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0043214 - ABC-type bacteriocin transporter
                     activity [Evidence IEA];
                     GO_process: GO:0043213 - bacteriocin transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HFS4996028.1"
                     /translation="MIKSFPFVQQQDEKDCGVACLSMILKYFKTDIPIHKLRDLSGTD
                     LEGTSAFGLKKTFEKLSFDCMAIQADSEIWKERDLILPLIAHILVDNSYMHYVVIYKT
                     KGNVLWIADPANGKNRKTIEAFQKEWTGILLLPMPRETYIPIKEKVAGLSSFLPIIWK
                     QKGLVFHIVLASIFITFFGIGSSYYFQGILDFFIPNQARSTLNIISIGLIAVYLLRVL
                     FEYSRSYLLIILGQRMSMAIMLQYFKHVLTLPMNFFATRKSGEIISRFLDASKIIDAL
                     ASATLSIFLDIGMVLLVGVTLAIQNSTLFLITLCSLPFYVVAIFAFVKSYEKSNREEM
                     AAGAAVNSSIIESLKGIETIKAYSGEEKVYNRIDHEFVKLMKKSFRTVTLDNIQQGIK
                     HLIQLISSALILWLGSYFVMDNRISLGQLITYNALLVFLTDPLQNIINLQVKMQTAQV
                     ANNRLNEIFAIDSEKSNQSFEYMLSEQLFQQDITVKNVSFSYSMKAPTLNEISCTIPS
                     HSKTAIVGVSGSGKSTLAKLFVRFYEASEGSIHYGNINHLDIPFQILRDRVTYLPQES
                     FFFSGTIIENLIFGLDSPPSFEQIIEVCEIVQLNEFINQQPLRYETLLEEGGNNLSGG
                     QRQRLALARALLKNPDILILDEATSGLDTLLEHAIMNYLLNLKEKTIIFIAHHLPIAK
                     ACDQILVLHEGHLVEKGTHDELRFADGIYQKLWEI"
     gene            19336..19572
                     /locus_tag="ACG8ZV_000661"
     CDS             19336..19572
                     /locus_tag="ACG8ZV_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HFS4996029.1"
                     /translation="MFKHAKCKGTKYCGNAQTVGGGNNAWGKLGQVVGGLTTGAVGGA
                     GLGTAICGPACGVVGGLYGAVAGGAAAGWDARKK"
     gene            19591..19806
                     /locus_tag="ACG8ZV_000662"
     CDS             19591..19806
                     /locus_tag="ACG8ZV_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HFS4996030.1"
                     /translation="MHIKNTKTTFILSSEELKNIQGGSAVGVLGTTFSGATAGVKLCS
                     AGGPYAIAACGVGGALLGAGFSMWTGA"
     gene            complement(20509..21261)
                     /locus_tag="ACG8ZV_000663"
     CDS             complement(20509..21261)
                     /locus_tag="ACG8ZV_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFS4996031.1"
                     /translation="MSYPIILCEDQIIQLNQLERIIDNFILFHDKVFKIVLKTQSPLE
                     VKKYLKQFRPKQGIYFLDIDLNHEVNGIELAEVIRKYDVQAKIIFTTTHDEMLPVTIK
                     RRVETLGFVTKDQTLDEYRNEIVELLLLAQERIDATKQVTNQAFVFSIGSQTFTFDIN
                     DIYFVEASKLPHRLSLCTKDGQYEFYGRISELEKKYPMLTRISRACLVNIFNVKEIDF
                     KKRSLYFDSELARNFTLGKAQKIKEKLKESTV"
     gene            complement(21276..22523)
                     /locus_tag="ACG8ZV_000664"
     CDS             complement(21276..22523)
                     /locus_tag="ACG8ZV_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFS4996032.1"
                     /translation="MFVGNFFFFLLFYMTNTDLNKRKYLFVCLLIPLTFFVELFTDVS
                     AAIPIIGSYFILKEKKKTNIVLLNKLLLCMLIDDFRSIITSMVMTYMFSFEGIKGYGY
                     VVFQIMLDSLFLLMFIWLYRKLAINRIVEQSSSKLTAIFMIYLLTIGLFVSYVAHQYQ
                     VFDHFVFGVLIFLIIQMFVVLFLFIRITIRQREQYEQQLKRKELVYLKKYTDSLEKDQ
                     EKFARFRHDYKNLLLSLKEIANQNHDSILEKEIKELEIYSNSYLTNKFEYRYLKNIKN
                     EYLKSLLIAKLYQANNNKICCKFECPSTIIEVPVPIFDCIRVLGIILDNAIEASIESQ
                     DRELSLAIYRDDKQIEISISNSCREILLSIDTLMKKGITTKKGHQGLGLSSIEEINKK
                     NPNMFVNYQNDPYQFTTQVILLF"
     gene            complement(22599..22745)
                     /locus_tag="ACG8ZV_000665"
     CDS             complement(22599..22745)
                     /locus_tag="ACG8ZV_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HFS4996033.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFSLF
                     KKCN"
     gene            complement(22849..23160)
                     /locus_tag="ACG8ZV_000666"
     CDS             complement(22849..23160)
                     /locus_tag="ACG8ZV_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFS4996034.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPGPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(23162..23359)
                     /locus_tag="ACG8ZV_000667"
     CDS             complement(23162..23359)
                     /locus_tag="ACG8ZV_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HFS4996035.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(23753..25480)
                     /locus_tag="ACG8ZV_000668"
     CDS             complement(23753..25480)
                     /locus_tag="ACG8ZV_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HFS4996036.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(25473..26666)
                     /locus_tag="ACG8ZV_000669"
     CDS             complement(25473..26666)
                     /locus_tag="ACG8ZV_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HFS4996037.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(26853..27497)
                     /locus_tag="ACG8ZV_000670"
     CDS             complement(26853..27497)
                     /locus_tag="ACG8ZV_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFS4996038.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(27591..27725)
                     /locus_tag="ACG8ZV_000671"
     CDS             complement(27591..27725)
                     /locus_tag="ACG8ZV_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HFS4996039.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(27727..29859)
                     /gene="feoB"
                     /locus_tag="ACG8ZV_000672"
     CDS             complement(27727..29859)
                     /gene="feoB"
                     /locus_tag="ACG8ZV_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HFS4996040.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(29856..30329)
                     /locus_tag="ACG8ZV_000673"
     CDS             complement(29856..30329)
                     /locus_tag="ACG8ZV_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HFS4996041.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            30730..30954
                     /gene="nrdH"
                     /locus_tag="ACG8ZV_000674"
     CDS             30730..30954
                     /gene="nrdH"
                     /locus_tag="ACG8ZV_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HFS4996042.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            31113..33272
                     /gene="nrdE"
                     /locus_tag="ACG8ZV_000675"
     CDS             31113..33272
                     /gene="nrdE"
                     /locus_tag="ACG8ZV_000675"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HFS4996043.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFLSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYAMAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            33322..34287
                     /gene="nrdF"
                     /locus_tag="ACG8ZV_000676"
     CDS             33322..34287
                     /gene="nrdF"
                     /locus_tag="ACG8ZV_000676"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HFS4996044.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(34376..35515)
                     /locus_tag="ACG8ZV_000677"
     CDS             complement(34376..35515)
                     /locus_tag="ACG8ZV_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFS4996045.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAV
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(35824..36537)
                     /locus_tag="ACG8ZV_000678"
     CDS             complement(35824..36537)
                     /locus_tag="ACG8ZV_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HFS4996046.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(36791..37492)
                     /gene="nagB"
                     /locus_tag="ACG8ZV_000679"
     CDS             complement(36791..37492)
                     /gene="nagB"
                     /locus_tag="ACG8ZV_000679"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004342 - glucosamine-6-phosphate
                     deaminase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HFS4996047.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            37726..39258
                     /locus_tag="ACG8ZV_000680"
     CDS             37726..39258
                     /locus_tag="ACG8ZV_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFS4996048.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(39449..40651)
                     /locus_tag="ACG8ZV_000681"
     CDS             complement(39449..40651)
                     /locus_tag="ACG8ZV_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4996049.1"
                     /translation="MKSNEKKPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMAALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTVFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQTVVFKG
                     KRNLENKK"
     gene            complement(40733..41422)
                     /locus_tag="ACG8ZV_000682"
     CDS             complement(40733..41422)
                     /locus_tag="ACG8ZV_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFS4996050.1"
                     /translation="MKKKIIRLILISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(41528..41896)
                     /gene="rplL"
                     /locus_tag="ACG8ZV_000683"
     CDS             complement(41528..41896)
                     /gene="rplL"
                     /locus_tag="ACG8ZV_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HFS4996051.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(41949..42452)
                     /gene="rplJ"
                     /locus_tag="ACG8ZV_000684"
     CDS             complement(41949..42452)
                     /gene="rplJ"
                     /locus_tag="ACG8ZV_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HFS4996052.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(42656..42783)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(42862..43551)
                     /gene="rplA"
                     /locus_tag="ACG8ZV_000685"
     CDS             complement(42862..43551)
                     /gene="rplA"
                     /locus_tag="ACG8ZV_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HFS4996053.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(43655..44077)
                     /gene="rplK"
                     /locus_tag="ACG8ZV_000686"
     CDS             complement(43655..44077)
                     /gene="rplK"
                     /locus_tag="ACG8ZV_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HFS4996054.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            44420..45088
                     /gene="sdaAB"
                     /locus_tag="ACG8ZV_000687"
     CDS             44420..45088
                     /gene="sdaAB"
                     /locus_tag="ACG8ZV_000687"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HFS4996055.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            45101..45973
                     /gene="sdaAA"
                     /locus_tag="ACG8ZV_000688"
     CDS             45101..45973
                     /gene="sdaAA"
                     /locus_tag="ACG8ZV_000688"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HFS4996056.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(46064..47164)
                     /locus_tag="ACG8ZV_000689"
                     /pseudo
     CDS             complement(46064..47164)
                     /locus_tag="ACG8ZV_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324221.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
     gene            complement(47256..48143)
                     /locus_tag="ACG8ZV_000690"
     CDS             complement(47256..48143)
                     /locus_tag="ACG8ZV_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFS4996057.1"
                     /translation="MTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEVSDKEKT
                     AESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDGQIQATG
                     DLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSMGGVSAL
                     RYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQDYQQMI
                     GNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTGENASHS
                     MLHENQEVDQLVSRFIWKE"
     gene            complement(48220..48765)
                     /gene="nusG"
                     /locus_tag="ACG8ZV_000691"
     CDS             complement(48220..48765)
                     /gene="nusG"
                     /locus_tag="ACG8ZV_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HFS4996058.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(48866..49036)
                     /gene="secE"
                     /locus_tag="ACG8ZV_000692"
     CDS             complement(48866..49036)
                     /gene="secE"
                     /locus_tag="ACG8ZV_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HFS4996059.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(49060..49212)
                     /gene="rpmG"
                     /locus_tag="ACG8ZV_000693"
     CDS             complement(49060..49212)
                     /gene="rpmG"
                     /locus_tag="ACG8ZV_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFS4996060.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            49374..50018
                     /gene="cbpA"
                     /locus_tag="ACG8ZV_000694"
     CDS             49374..50018
                     /gene="cbpA"
                     /locus_tag="ACG8ZV_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-AMP binding protein CbpA"
                     /protein_id="HFS4996061.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(50074..50577)
                     /locus_tag="ACG8ZV_000695"
     CDS             complement(50074..50577)
                     /locus_tag="ACG8ZV_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HFS4996062.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(50590..50636)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            51174..52139
                     /locus_tag="ACG8ZV_000696"
     CDS             51174..52139
                     /locus_tag="ACG8ZV_000696"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFS4996063.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGDDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(52238..53410)
                     /locus_tag="ACG8ZV_000697"
     CDS             complement(52238..53410)
                     /locus_tag="ACG8ZV_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4996064.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMPTIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(53397..54542)
                     /locus_tag="ACG8ZV_000698"
     CDS             complement(53397..54542)
                     /locus_tag="ACG8ZV_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4996065.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(54556..55480)
                     /locus_tag="ACG8ZV_000699"
                     /pseudo
     CDS             complement(54556..55480)
                     /locus_tag="ACG8ZV_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            55597..56676
                     /locus_tag="ACG8ZV_000700"
     CDS             55597..56676
                     /locus_tag="ACG8ZV_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFS4996066.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            56673..57301
                     /locus_tag="ACG8ZV_000701"
                     /pseudo
     CDS             56673..57301
                     /locus_tag="ACG8ZV_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
     gene            complement(57411..57638)
                     /locus_tag="ACG8ZV_000702"
     CDS             complement(57411..57638)
                     /locus_tag="ACG8ZV_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFS4996067.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(57741..60329)
                     /locus_tag="ACG8ZV_000703"
     CDS             complement(57741..60329)
                     /locus_tag="ACG8ZV_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HFS4996068.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(60349..61008)
                     /locus_tag="ACG8ZV_000704"
     CDS             complement(60349..61008)
                     /locus_tag="ACG8ZV_000704"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFS4996069.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVAQHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(61057..61560)
                     /gene="trmL"
                     /locus_tag="ACG8ZV_000705"
     CDS             complement(61057..61560)
                     /gene="trmL"
                     /locus_tag="ACG8ZV_000705"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008175 - tRNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HFS4996070.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(61781..62647)
                     /locus_tag="ACG8ZV_000706"
     CDS             complement(61781..62647)
                     /locus_tag="ACG8ZV_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HFS4996071.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            62756..63397
                     /locus_tag="ACG8ZV_000707"
     CDS             62756..63397
                     /locus_tag="ACG8ZV_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HFS4996072.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(63459..64820)
                     /gene="mgtE"
                     /locus_tag="ACG8ZV_000708"
     CDS             complement(63459..64820)
                     /gene="mgtE"
                     /locus_tag="ACG8ZV_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HFS4996073.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(64838..65737)
                     /locus_tag="ACG8ZV_000709"
     CDS             complement(64838..65737)
                     /locus_tag="ACG8ZV_000709"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFS4996074.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(65739..66536)
                     /locus_tag="ACG8ZV_000710"
     CDS             complement(65739..66536)
                     /locus_tag="ACG8ZV_000710"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HFS4996075.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(66514..67218)
                     /locus_tag="ACG8ZV_000711"
     CDS             complement(66514..67218)
                     /locus_tag="ACG8ZV_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HFS4996076.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            67349..67924
                     /locus_tag="ACG8ZV_000712"
     CDS             67349..67924
                     /locus_tag="ACG8ZV_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HFS4996077.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            68042..68719
                     /locus_tag="ACG8ZV_000713"
     CDS             68042..68719
                     /locus_tag="ACG8ZV_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClpXP adapter SpxH family protein"
                     /protein_id="HFS4996078.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
     gene            complement(68798..70606)
                     /gene="pepF"
                     /locus_tag="ACG8ZV_000714"
     CDS             complement(68798..70606)
                     /gene="pepF"
                     /locus_tag="ACG8ZV_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HFS4996079.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSDAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(70782..71780)
                     /locus_tag="ACG8ZV_000715"
     CDS             complement(70782..71780)
                     /locus_tag="ACG8ZV_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA family protein"
                     /protein_id="HFS4996080.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(72006..72659)
                     /locus_tag="ACG8ZV_000716"
     CDS             complement(72006..72659)
                     /locus_tag="ACG8ZV_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HFS4996081.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
BASE COUNT        21875 a        15042 c        12402 g        23646 t
ORIGIN      
        1 gtgaatggat atttactttt aatagataaa atattataac tattaaaaat aactattttc
       61 attataatta cacacaaaaa agagcgtgag acaaaagtaa agaacacttt tgtctcacgc
      121 tctaaacacg tataaacagc ggaagcagaa gcaactcctt cggaaataag ctgaaattca
      181 caaaaatttg aaaagcaatt tccgtgaatt tcttcttatt tcttggagtt aaacgcttct
      241 gttccagcct ctttttatct gtctttcact aatgatcagt tgtagataag caagttgctt
      301 tttcttacat cataccgccc atcattgatg gatccattgc aggagctgct ggcgctgctg
      361 gttctggttt atctgcaacg actgcttctg tcgttaataa caaggcagaa acggaagcgg
      421 cattttgcaa ggcagaacgt gttactttag ttgggtctac gatacctgct tcaaccatgt
      481 ttacccattc tccagtagca gcattgaaac cagtgcctag ttccacgttc ttcaatttat
      541 caacaatcac tgatccttca taaccagcgt tttcagcgat ttgacgaatt ggttcttcta
      601 aagcacgaac aacgatcttg atacctgttg ccacgtctcc ttctgcttct acagcagaaa
      661 ctttgctgat aacgttcact agagctgtac caccacctga gaccattcct tcttctactg
      721 cggcacgtgt agcattcaat gcatcttcaa tgcgtaattt taattctttc aattctgttt
      781 cagtagctgc accaacttta acaacagcta caccacctgc taatttagct aagcgttctt
      841 gtaatttttc gcggtcaaaa tcagaagttg tttcagcaat ttggtttttg atcaattgca
      901 cacgagcttc gattgcttct ttttctccag aaccttctac gatcgttgta ttgtctttat
      961 ctacaacaac tttagaagca tttcctaagt tttcgattgt tgcatctttc aattctaaac
     1021 ctagatcgtc agtaattact gtaccacctg tcaaaatagc gatatcttca agcattgctt
     1081 tacgacgatc gccgaaacca ggagctttta cagctactac gttgaatgtt ccacggattt
     1141 tgttcaatac aagagttggc aatgcttcac catctacatc gtcagcaata atcaacaatg
     1201 gacgtgattg ttgcaagatt tgttctaaca atggcagaat atcttggatg ttagagattt
     1261 ttttgtctgt gatcaagata tatgggtttt ctagaacagc ttccattttg tcgttatctg
     1321 ttaccatata ttgtgataag taaccacgat caaactgcat accttctaca acatctagtt
     1381 ctgtttcgat cccttttgat tcttcgattg tgatgacacc gtcgtttcca actttttcca
     1441 ttgcatcagc aatcaaatgt ccaactttat cagaacccga agaaacagct gctacttgtg
     1501 caatggcttc ttttgaatca acaacagttg agatattatg caattcttcg actgctgctt
     1561 ttgttgccaa ttcgatcccg cgacgaatgc ctagaggatt agcacctgca gttacgtttt
     1621 ttaaaccttc gcgaacgatt gcttgtgtca gaacagttgc tgtcgttgta ccgtctcctg
     1681 caatatcatt tgtttttgat gctacttctg atacaagttt tgcacccatg ttttcaaaat
     1741 gatcttctaa ttcgatttct tttgcgatcg tcacaccatc atttgtgatc aatggagagc
     1801 cgtaagattt ttctagtacg acatttcggc ctttaggtcc taatgttact ttcactgtat
     1861 ctgctaattt atctaccccg cgtaacatag ctgcgcgtgc gtcttctgca aatttcaatt
     1921 cttttgccat gattgattca cctcattgat tatttttgat tattttttta tcttccaaat
     1981 ttactcaaca atcgccatga tatcttttcc tgcgacgatc agatattctt ttccttcgta
     2041 ttttacttct gtaccggcgt atttttcgaa cataacttgg tcgcctgctt ttacagcggc
     2101 aggaactttt tcaccgtttt ctaacaaacg gccttcaccg actgcaacaa ctgtcccagt
     2161 ttggggtttc tctttagcag cagaagctaa aacgattcct ccgacagttt tttcttcttc
     2221 ttttgcgact tcgataatga cgcgatcacc taatggtttt aacacgataa atccctccga
     2281 taactctttt tttaatctgt tagcactctt aaccttcgag tgctaaccta catttttaat
     2341 aatactcatt ctccctcttt tttgcaagct tttaaatcaa agaaaagaaa ttttattctg
     2401 acagctgctt attgaaatta tgatataatt gaaatcaatc gatataagct tgccttgcat
     2461 gcttgttatc ccttaaaagg aggaattaca tgtctttaaa aaaatatagc ttcctcagca
     2521 ttttttgcta tggtctaatt tttatctcac ccttgatcct agcttcgata ggacttgtaa
     2581 aatctacgtc tgaattgatc acagcaactg cagtcatgta tatactaggc gccgttgtcc
     2641 tagctatttt ttattttaag caacgtgaac ccttagcgat cgaatcagcg gtaaaaaaag
     2701 cttctgctcc aaagattgtt atttatggat tggttggaat ctttgtcgca ttgattctgc
     2761 aaagcatcgc tgtcatgtta gaatctgtat tgtttggcaa agcaacccct tccgagaata
     2821 cacaaaatat catccagatg atcatggaag cacccgcttt tattttggcg acaactgttg
     2881 ctggacccat catggaagag ttcgtattcc gccgcagtat actggggatc atcagtcgat
     2941 attcaaattt ttgggtcgga gcagtgatca gctctttgct gtttgcgttt gctcataatg
     3001 atggtcatct gctaatctac tttttcctag gtttcttctt cagcctagag tacaaagcaa
     3061 ctggtcggat ctggacatcg atgatcacac acgtaggaat gaacacatta gttgttcttg
     3121 ttcaattagc tgtccaaaaa gggctagtat aaacatgact ataaatactc ctgtcatcct
     3181 agattggtga ttttcccaat ctaaagcgac aggagtattt ttgtttttta gtcgttcatc
     3241 ttttctgctg ctccatcatt ttttgtctgt ctttcctttt tgcagtttgc agaatctatt
     3301 tttttcaaaa atgggaaata aatgaaaaaa ctaattgaca acacgatacc ttgtaaaatc
     3361 gctgcaggca ctccgcctac taagaaaccc gagaggatcg gcggtgttgt ccaagggact
     3421 tggactgctg taaataaagg aacgaatcca aaatataaag cggaataggt aatcaatcct
     3481 gaaacgaccg gtgcgaaaat aaaaggaaca gccatcatcg ggttcatcac gatcggtgtg
     3541 gaaaaaataa ttgattcatt gatgttgaaa aaggctggta aaagagcaag atttcctaat
     3601 tctctgtatt tcttcgattt cgcaaaaacc gtcataaaaa atacagcccc taacgtcaat
     3661 ccagcacccg taaccgtcat gaactgatcg agaaattgct gagtaacgat atgtccgcca
     3721 tttgccaccg tcaactcttg tcctgaggct aagatttctg catttgctaa tgaattcgct
     3781 tgcaagacgg gactaaccaa cccattgacc atcgcagatc catgaagacc aaataaccat
     3841 aaaaacggaa caaaaaaacc taataaaagc acaccaaaca acgtgtctat gaacgattga
     3901 atgggaagct ggacatatgt ccatactcct tgaacaacag tcattctgaa caaatgttga
     3961 aaaaccgctg aaccgataag cgtaaaagtg actataacaa tgattggaat caatgaagta
     4021 aaagactgcc aaacattttc aggtatcttc tctctttgct tccacccttt cgcaagtctt
     4081 actaaacgtg catagcccca tccgatgatg agcccagttg taactgctcc tagtatccct
     4141 tcagcacctg tccagacagt atctatctga gtatttagtg gctgaataag cagtagataa
     4201 gcagacaagg ctgttatgcc gactggtaag cgatcgatgt cttcttcttt tgcataagcg
     4261 tatgcaatgg caaaaacgat ccaaaaggct atcacatcaa atgtagcctg gtatacttgt
     4321 gtaaaataca tagaaaatcc tgttttgtct atccactgag cgatgtaatc cacaggaaaa
     4381 tgagcaaata agaaaaacag cgagccaaca ataattattg ggatcgtgta agtcattcca
     4441 ttacgcaaag cagttaaggg tctaagattc acaacagatg ttatcattgg taaaaaggca
     4501 cgatctaacc actctttcat ttcttatctc cttcaacttc tatttttatc aatcagtttt
     4561 cttaatttaa ctatacccaa tgatcacgaa ccatgaaagg aatgcgcact gagcttttca
     4621 aaaatcggat tctttgacga atattcagca actgcttaca atggacagga ataaaaaagg
     4681 aggtttttta tgaaaattgc actcattgga gctactggcc atgcaggttc atttatttta
     4741 gacgaagcat tgtccagaga tttagacgtg acggcaatcg tgcgtcatcc agaaaaattg
     4801 ccatcagatg ttccgtttat acaaaaggat ttatttgagt tgacaactac tgatcttgca
     4861 tcttttgatg ttgtcgttga tgctttcaac gctcccaaag gaaaagaaga aatgcatcaa
     4921 acttctttgt cccatttgat tgagatgctt gaaggaaccg atacacgctt aattgtcgtt
     4981 gggggtgcct cttcgttatt cttagataca gaaaagacga ctcgtatgat tgaccaagta
     5041 cctaaaaatg cacccttcta tccaacagct ttcaatatgt acgaaggatt gttaaaattg
     5101 aaacaatcta aaaatctaca ttggacttat atcagtccag cttctttatt tgatccacat
     5161 ggcaaacgta caggtactta tttgttaagt gatgattatt tacaaagaaa cgctgctagc
     5221 gacagtacga tcagcatggc agattacgcg attgcattag tagatgagat actggatgag
     5281 aaacatgaaa agcagcacat cagtgtagtc agtcgataat acggttattt ttttaatatg
     5341 ctaaaaaaat aaaaatagaa gataaaacca accctgattg attttatctt ctgcttttta
     5401 tatttttatt gattgaactg tttaaatcga aaatagctca gttgcttcat ctggatctgt
     5461 atcatagatt tcaaaatcat gtccaacgcc aaaatctttt tctttcaaaa cattttccat
     5521 tgttaaatga gcaagttctt tcatattgtt ttccttgcta agatggccaa gatagattcg
     5581 tttggtccga ttaccgatca catcagtcat gacaagtgca ccgtcttcgt tggaaagatg
     5641 tcctctatct cctaaaatac gctgttttaa attccacgga taaggtccca tgcgtaacat
     5701 ctcaagatca tgattacttt ccatcaaata accatcggca ttttcaatga cacctcgcat
     5761 ataatcactg caatatccgg tgtccgtcaa catgacgaat gaccgatttt ctttatggaa
     5821 acgataaaat tgcggagccg ctgcgtcatg ggagacgccg aaactctcaa tatcgatatc
     5881 gccgaatgtt ctgactttcc ccatctcaaa tagatgtttt tgttccactg gtacatttcc
     5941 aatcagtggt tccatcgctt cccaagtctg ctgattggca aaaacatcca aatgatactt
     6001 acgagccaag acacccacgc catgtatatg atctcgatgt tcatgcgtca caagtattcc
     6061 atctaattgg tccggtgtcc gatcaatttg agccatcaag gaagtgattt ttttaccgct
     6121 aagtcctgca tcgaccaaaa gccgtttttt ttcactttcg atataaagtg aattacccga
     6181 acttccactt gctaggatac tgattttaaa agctggtttt tcttcagcca tttgactcct
     6241 acttcccttc ttactttgta aacttttttc attatactcg cttttttatt gatcttccac
     6301 ttttggtaca gtattgtttg tcacgatcgt attgctgaaa gcgttgacgc tctcaatttg
     6361 gaccacttta tcgcttgttt cgatcgctac atgccaaaca ggaacataca catttttttc
     6421 ccggactttc agaatacagg aataagctag ctgacgccat aaaatttttg atcctcttgg
     6481 tattttgtta ttgatgtaca atgtattgat tgcttcctct tccgtataca gttccgtctt
     6541 ttcgcgcagc tgctcgatat cagataaatg cgtctgcatg tatttcgtga tgctataatc
     6601 attatcgttt ttttctaaag aaagaacgat ttttgctgta tcatcattga atgggatgcc
     6661 ttcatactct tggcttgctt ggatttctag tggttcttct tctaaatgag aaaagttttt
     6721 cgtgtacaca taatcattac cgaataaaat attgtctttg ttagataaaa aatcttccaa
     6781 ggaactacta attttatctg gatcgatcac gttcttttca gcatctgaac tggataaaga
     6841 tttcgtcaaa acatcaccgt ctaaaaacac accacttgcc agcaagccgc ttttaccagc
     6901 cttgcgataa ttcgctaatg aagtgctaag attggtctgc tccgcgctaa gataatagcc
     6961 ttgcttgttc tcagacgaaa tcttccccgt gtaagtgata tcgtcgctag ccagacgttg
     7021 ttggattgat tcagtctgat tagagcgaat gacattgttt tcttggtata ccgcgtcatg
     7081 ataactgctg aataaaaaca cattcaaccc taaaaaagcg acgaaaaata tccattcgat
     7141 ttttttgaaa tccaattaat tcgcctccaa tccaggtaat ttttccagaa ggtcgttagc
     7201 tgaataccag ttatctttat atttcacata ccattcaggt aagagatcaa cgacacgatt
     7261 cgtttctttg acattttgcc atgtatagcc aacgatcact gaaccaatct tgttgctatc
     7321 tgctccctta gcttttaact gctggatgat ttcattcgta cttgcaagtt ctacttcttc
     7381 gtctgaaggt atcggcactt gaatcgtatt caaactggtt tggatattca cttgcacaga
     7441 accattcgtt tcaccgccaa cttccacacc aatctgtcct ctgctgtctg tcccaaaaac
     7501 cgggaagcct tccacgaata tccgataatc gatcgtattg tcactgcggt caaaatatct
     7561 gaggttccct aaagaactgc ctaatttgct aatatagggg aaactttcag aaaatacact
     7621 agcattttct tttttctctg gcagctctcc acgaaaatca actacttgcg tttccgaatg
     7681 gatagacatt gtttcattcc caccgtaaaa aatcaattca ttgctttcat cattattttt
     7741 cacgctatct ggtttctgga aaaaagcatt tctaaaaagt gtatagggtt gctgtgacag
     7801 gatataacta tacttcttca gtttgatcga atgtttcgta gcatattgcg tgtcgatcgt
     7861 cgatggttct gttgtcattt ctgtccattt tgtgtctttt gctgttaatt ctttattgat
     7921 atctgtccaa ttcaacgaaa tatttgcttc atatacgaga tggttcgaat aattcaaaaa
     7981 tcggattttt ttatttcctt gatcgaattg tattctagta aaatacatat tttcgctttc
     8041 ttttgccaag ttcgacacat ctaaatctaa atcaaatgct tccttgtatt ctcttagcaa
     8101 aaaaggcgca ttataggcca actcaaaacc agagttcaga tttttcacct gttcaaactg
     8161 tgatttgtct cctgaaacta cttcagaaag ctttccaaat cttgctttat cgatgatcaa
     8221 ttgcaatcgg tacacgagat tttcactgtt ggtttcttgg atcattcccg aatggtgcca
     8281 tgtaacatga agcggaagaa agacttcgga agtttttcga ttgctttgag actcgatcat
     8341 ttgagtgttt gtctcatcta cgttgattga actttttcct gctgggctca gccagattgc
     8401 ataagagaag tatatgctta acgcaaccat caaaatgagt cctatacgaa cgactttttc
     8461 agagattctc attcccacca ttcctcctca taaggttcat atggcagcga gatataaaaa
     8521 gtcgaccctt ttccttcctt gctctctgcc caaatagcgc ctcgatgcgc cttaatcact
     8581 tctctagaaa tagctaatcc aagtcctgtc ccaccttgtg ctcttgcacg tgctttatct
     8641 actcgataga accgctcgaa cactcggttc agatcttttt taggaatccc caatccttga
     8701 tcggtgatac ttaaaatcac gttattatgc gtttctaata agcgacaagt aatcgttccc
     8761 ccatctggtg aatacttgat cgcgttattc atgatattat cgactacttg gatgatttta
     8821 tctgtatcta cttcgaccca aagatctctt tgcgtaaatt cacgacggat cttataattt
     8881 ttttcctgat ttcccaccat catatcaaac cggtcaagaa caaaattcac taactcgttg
     8941 aaattgacat attctaattg aagctgggta ttacctgtat ccatgcgaga tagatttaag
     9001 aggtcattga tcattcgaat cattcggtct gtttcatcta gcgttacctt caaaaaattt
     9061 ggtgctactt cctcgtcttt ccacgcacct tcgctcaatg cttcgatata actacgcata
     9121 cttgtcaacg gtgtacgaag ttcatgggaa acattagaga cgaattcacg acgttcccgt
     9181 tctgtttttt cttgttctgt cacatcatgc aagacagcta ctaatccgct gataaaacct
     9241 gattcgcgac ggatcataga aaagtctact cgcaagatca tctgatcact ttccaatgta
     9301 ctggttgaac ggtcaagtac catttcgttt ggatcttcta ataatttccg caacgtatat
     9361 tcttcttcga tatctaaaag tgtcaaaatc gattgtccga ttgcttcctc gtttttgata
     9421 tctagcaagg aaacagccat atcattgatc gtaatgactt tacccctgcg atctgtcgca
     9481 atgacgccgt ctgtcatatg ggatagcacg ctatccaaac gattgcgttc agcttccatt
     9541 gtatcttgag cttcttcaat acgttcagct aactgattga aggtatcagc cagctgtcca
     9601 agttcatctt gtccatgcac tttgactttc cgactgtagt ctcctctagc gattcgaatg
     9661 gcttgttctc tcatttcacc gatcggctgt gtaatcgaac gagcaactaa aacagatacg
     9721 atcattgaaa taaatgccgc aattagtgag gcagtaaaga aaatgactgc tgtgttattg
     9781 atttccgaat atttttgttc gatattactt ttgacgtaaa gagccccgat aacggcatcg
     9841 ccggtcgggg acaggatcgg ttgaacattg atattcaccc gtttatcgtc gttatctaaa
     9901 gcaacataac gtttagtcgt gaaatcattg atatcaacat aatcattttt ctttcccaca
     9961 gcgctttgtt cattgacatc ggttgttcct cggatgatcc ctttttcgtc aacgacccgt
    10021 atttcgatga tatcgctagt cgcactgttt tcaataaatc ttttgatatt cgcatttacc
    10081 tcttcatcat ctgcattatc ttttcgattc aattccgggc tgattgttgt tgctaatgat
    10141 tccaccgttt gattcatatc tttaataaat gtattgatcg tggaacgttc taaaccacgt
    10201 ataaagtagg caccaataat ttcgatcgag atcaataaaa tcagaataaa ggtaatagcg
    10261 atcttaaaat tgactgatcg aaaaaagcgg acttttcttt tcatccaatt actcctgttc
    10321 tgggttacgc aaatagtaac cgacaccacg acgtgtcact aaataatttg gatggcttgg
    10381 attatcttcg atcttttcac gcaaacgacg tacagttaca tccactgttc gtacatctcc
    10441 aaaataatca taaccccaaa ccgtttgtaa taaatgttct cttgtcatca cttgtccaag
    10501 gtgcttcgcc aagtaaaaga gtagttcgaa ttcacgatgt gttaactcga ttgtttctcc
    10561 tcgtttcgtc accatgtaag cttctggatg gatcgtcaaa tcaccaatcg tcaattccgc
    10621 aggtgctgcc tcttctggtt ccttcgcagc cgtggcaccg cgacgaagat ttgctttgac
    10681 acgtgcaact aattctcggt tggaaaatgg cttggtcacg taatcatcgg cgcctaactc
    10741 taagcctagg actttatcaa tttcagaatc tttggctgtt accataatga tcggcatatc
    10801 ataagttttg cgtacctcac gagcaacttc taagccgtcc attttaggta gcatcaaatc
    10861 aagtaaaatc aaatcaggtt ctacctcagc aactttttcc aaggcttctt ccccatcata
    10921 tgcagtataa acgtcatagc cttctttggc taaattgaat ttgacgatat ccgaaatcgg
    10981 cttctcatca tcgacaacta aaactttttt cataaagagc cacctcttat atattattgt
    11041 cataccttct cattataccg tatttctgct tttgtttcat ctttgcctat aaaacaaaag
    11101 agaaaattaa aatgaaagtg caaaatactt tattattttt tgttctaact tcaataaaaa
    11161 aggaaaacac tgattttcac ctcagtgttt cctttttttg atttatcctt ctaaaacttg
    11221 tacaccgaca cccaataatc ccggaccagt gtggactact aatgccggag aaatctggcc
    11281 aaagtagatt tggtttgctt gtgggaactc tcttttaagt ctcgcttcca tttcaattgc
    11341 ttcttctttc gcatccccat gggcaacagc taagttgaag acctttgcat taccgatttt
    11401 ttctttgacg taagcaaccg ttttatccaa acttttttta cgtcccctag cttttcctac
    11461 tgtgtaataa atcccttctt cattacatga gatgattggg ttaagcttta aagcggttcc
    11521 tacaatagaa gcaactaaac cgatccgtcc acctttttga agatattcca atgtcgcaac
    11581 attaaagaaa acttttgttc tttcgactaa ctcattcaga ttactgatca gttgatccca
    11641 ttctactcct tcttccagcc attttgctgc ttggatcgca gaaaaacctg caccaatacc
    11701 aatatttttc gtatctagta catatgcttc caattcttct tgctgttgtg caattaaacg
    11761 aaccacatta tatgtcccgc tcaatccact ggaaattgtt accgcaagta ccttttcata
    11821 accgtctttt ttgatttgct caaagatttc tgtgatcgac tcaccatccg gcaaagatgt
    11881 accagggatt tcctctggca aacgttgata gatctcttca ggggtaatgt caattttatc
    11941 tgtatatacc tgatctttat aaataatttt caatgggatc atatacatct cgtatttttt
    12001 tatcaattct tctggaacat ccgtacctga atctactaaa attgcgattt tattgttttt
    12061 catttgtttt ctcctctttt aaatattcgg tttctagaac aatcgttttt tccgcaagaa
    12121 gtttcattgc aaacgataaa gttgccgctc ttacagcaat atattctaca ggggttgcct
    12181 ggtcgaattt ttgcggatga gatttacctt gtgctaattg gctgaccatc cacacagctg
    12241 cttcttgttc atcgcaaaat agattatagg cttcacgaat tcctactgtt tttccttgga
    12301 acaatatccc ttctttgatt tcaggaatag tcaatacttg tttcaacgta gtgattgcaa
    12361 gtaaaaatgc tacgtgttct ttgttatatc tttttttaac tggtgctggt atcaaaccta
    12421 gtttaacgta attgtttacc atagaagagg taagcaatgg atgcttttct ccttgtatca
    12481 caggtgaaag ataacgatca actaacgttc tgacttggtc catataaagt tctaagtcag
    12541 ggagttcttc ccagtgaggc agacggaatg tttctagttc cttcccccac tccattaatt
    12601 gctgacgcat tttttccatc ataaccgctc cttttttcat ttcataaaca tgatatcaga
    12661 cttatgataa acattcaatc tagttgcttt aactaggtga tttgattagc gggattctat
    12721 gaaaacaaaa aacaagaagg ctaagccttc ttgtctttta tcgttaagaa caggagaccc
    12781 gccggggaga cggcgggaaa ggagtaaaaa atgaaaaaag tgttagggtt tgttctcttg
    12841 caagaacttt gtttgttggt atgcttatat aatagcgagc aaatgtgaat aatctatgaa
    12901 tgatttccta taaggaagta aagatttttc tgattttctt taaatgtagt cttgcatttt
    12961 aaaattctta gtgctactat tattaagtac tttttgtacg ggccgttagc tcagttggta
    13021 gagcagctga ctcttaatca gcgggtcgcg ggttcgagcc cctcacggcc cattgggtgc
    13081 caaacccacg gaacaggtaa atgttggtgc gaaagcattt cgaaaacatt tacgctgttc
    13141 tttttttatt tttcaaaata actagggctt tttattttta actcaaagtc cactgtagcc
    13201 ctttggactt tgagttaaaa aagaagcata attatgaaca gtaaagtttc taatataaca
    13261 ataattcgag aagctttgca aaatcatgct gccaatgaac tctctaaaca tataggatta
    13321 aatctaagta ctataaaagg ttaaaaagtg aagaatattt aatagaaaaa ctaaatttac
    13381 ttgctgcttt ccccttttcc attaatacaa caatcagaga gtgtcttttt ttcgaaaaaa
    13441 ttagaataaa taaaagacac gtagtttttt tatctacatg tcttccatcg actacaagtt
    13501 atcatttctc aaaacgtatt tagcttttaa ttgattaatc gtttcacgtt gtctacacat
    13561 tgcctaatta agattttctt attagaagca tcaatcccgc aataatacct aaaactccag
    13621 gaattaccca caataatgtt aaaagaaaaa atggaataat agataaaatg agtaaactaa
    13681 taccatagac cactgttttt tgattttttc ttactaaaaa acctattatg aaaatcatta
    13741 tcgaaaaaac tagggtaatt cctccaaata aaacaacatt cccgcttaga ttgactaaca
    13801 tatctatatc cttactggtt agttctgtag tatttaaagt agttgaatca atagaagata
    13861 gaaacatacc acccatcaat gctaaaagac tacataaaat ccctgttatt ccactaatta
    13921 aaatcaaaat aaactctgtt tttctcttat tcatttaatt ctctccagat taagtgtttt
    13981 agaattagaa attttttgac catagttaat agcttctaat gaacgaataa caaccactga
    14041 cgtgttagaa aaataatccc caatatgttg tttcttgggc gtgaaagcag ccaccaaata
    14101 cccaatttga aatacaaaat tttttaatat aaacctacat atacactcac gaataaagat
    14161 agtttgccaa cttagctctt tttcctcaaa gctcactact cttatcccaa aaatcatttt
    14221 cccaattgtt tgtcctgaat tcagcttagt caaaagtaca aaataggtta aataaatagc
    14281 taatgacgct ataccataaa aagtaataat ggatttgtca gattccagtc ccatgatttt
    14341 gtaaaagaga cctatagtag catgggtgat gatgctaata caaattaaat caataagaaa
    14401 agcaaaaaat cgtaaccaaa atcccgcaaa tacataatta ggcaaagttt caatgccact
    14461 cttcttattc attttatagc cctccatagt aatacattgg ttttggagta tcagaaaatc
    14521 caagtttttc aaaaactgaa attacacgat ctgatgtagt tgcctttagc ccttgccatt
    14581 cagcaatctt attacctaac caagaagaag caaagccagt tgtgtcattt ttatattcta
    14641 taaccgtcgc atcagttaat ttcttctctt tttttaggga atctaatgca tcttcagagt
    14701 aaccaatttg atccaccaac ccattttcta ctgcttggtt accatcataa attcttccat
    14761 ccgcaagttc tttcactgca ttagtatcca tatttcttcc ttttgctaca acattgacaa
    14821 aacgatcata agcactcatc acaaattcct gtataacttt attctcttcc tctgaaggtt
    14881 tgtgttgagg tgacatcata tcttttaatg caccactttt atacgtcgca tcagttacgc
    14941 caagtttttc taataagcca gaataattta aaccagaaat aatgacacca attgatccag
    15001 ttgttgtttc ttccgtagca aatattttat ctgaaccagc agaaatgtag taccctccac
    15061 ttgccgctgt atttttaaat gcagtataga taggaatatc tagcttttta atttttgcca
    15121 tttctttagc aatctcagca ctttcatata ttcctccccc aggtgaattt acttctaata
    15181 acactccctt aaccgctttg tcttcttgaa ttttctttag ctgtgttaaa aaattctgat
    15241 ggttatattg ttccctacta aaaagattgc tttcacctgt atctgcaata actccattga
    15301 cggatagttt gacaatcttt ttatttgatg cgccttcttc taacgtttct tctgtgattt
    15361 cgttagatcc gtaaaaaatc ttatttattc ctgttagggt tgtatttgat gcttcctctt
    15421 tatcttttcc tggaattagc gcgacgataa tggatagtaa caataatccg cacgctactc
    15481 ccacagcaat ccatcttctt ttattcatat aaactcctcc tatattctta gtaaaaataa
    15541 ttatttttta tttagaaaca catcgacaat ttgttgccaa tatgtttttt ctcctacaat
    15601 taaagacaac tctccagtta atccataacg aaacggaaac gattgagttg tttttaacgt
    15661 tcctttcact gcataaaaaa cacctttctc agtggcagta gaattttctg aaatttcatc
    15721 taaagttccg tcgatcgtaa tcggagcccc acctttttga tccaatttaa aatgaacctt
    15781 catcccttct ttaatatagg tactttcatt cgcaggtaaa agtgctgtaa atttcatttt
    15841 tgatttttcg tggatcggat aaatttctgc aagcactgtt cctttggcta gttctgcttg
    15901 tccctttgtt tcttcattta aatgaaccgt tccagataca ggagctttta gtattccttt
    15961 tgaaagttga tcgtccaaac ttttgataac tgactggttc ttctcttgtt tttcatttag
    16021 ctctgtaact gtttgtttta cagttgttat tgcttgttct agctcttgct ttcctttttc
    16081 cgtttgacta attctgtcat tctcagaagt agttggttta actaatttag ctttttctga
    16141 ctgatactgt tctacttctt tttttagttg ctcaatttgt tcatttatgc ttgctgaaat
    16201 tgtcagtttc acttgatttt tttgatcatc agaaacatta tttagttgtt cttgccaatt
    16261 ctcatagttt gccatcattt cttttgaaaa atcttttaat gattgattat tactccaagc
    16321 tacctgtact tgttgccatt cttgtaattt actatctgaa ctctcaattt gtttttctag
    16381 ttgtcttttt gtcttttcgt atacttctaa ttgcttttga tcatttaatt cactttgctt
    16441 caaagcgtag cggagtgatt ctttttctga caacatgctc tttaattgat tactgtagcc
    16501 aaaactgtca tccgttgaaa acaaattttt tcctttactt atactttcaa taaatagctg
    16561 agccatcttt atttgttgag taatacgttg gttttcttgt tctatctgag ccttttcatt
    16621 ctctattaaa gaacaatcca atctaaccaa cacatcgtcc ttatgaacaa attgattttc
    16681 ttttaggaag ttttccatta ttttagcttc taatggcact tgtaacttct ctattttttc
    16741 ggggttcaat tgagccgttg tccgaataac aacctctttt ttagcaaagg ttaaaaacaa
    16801 tccaataata cataaaaaaa gaattacagg gtataacacc caacggtaga agctatgatg
    16861 ttgtttagta tagatactag aatgttcgaa ccaattatta ttctgcataa attgtttccc
    16921 tctcctagat ttcccataat ttttgataga taccatcggc aaaacgaagt tcatcgtgcg
    16981 ttcctttttc taccaaatgc ccttcatgga gaactaaaat ttgatcacat gcttttgcta
    17041 ttggtaaatg atgcgcaata aaaataatcg ttttttcttt taaattgagg agataattca
    17101 taattgcatg ttctaacaag gtatctaatc cactagttgc ttcatctaaa attaatatgt
    17161 ccggattttt taataaagcc cgtgctaagg ctaatcgttg tcgttgccct cctgaaagat
    17221 tatttccacc ttcttccaac aatgtctcgt aacgtaatgg ctgttgatta ataaattcat
    17281 ttagttggac tatctcacaa acttctatta tttgttcgaa acttggtggg ctatctaaac
    17341 cgaatataag attctcaatg attgttccac taaagaaaaa tgactcttga ggcaaatatg
    17401 tcactcgatc gcgtaatatc tgaaaaggaa tgtctaagtg attaatgttt ccataatgga
    17461 tcgatccttc tgatgcttca taaaaacgaa caaataactt tgcaagagtt gattttccag
    17521 aaccactaac tccaactata gccgttttac tgtgcgaagg aattgtacat gaaatttcgt
    17581 tcaacgttgg ggccttcatg ctatacgaga atgaaacgtt ttttacagtg atatcttgtt
    17641 gaaataattg ttcagaaagc atatattcaa aagactggtt cgatttttct gaatcaatcg
    17701 cgaaaatttc atttaaacga ttatttgcaa cttgagccgt ttgcattttc acttgtaaat
    17761 taataatgtt ttgtaaagga tctgtcaaaa atactagtaa agcattgtat gtgataagtt
    17821 gacctagact aattctatta tccataacaa aataagaacc tagccataaa attaatgcac
    17881 tgctaattaa ttgaatcaaa tgtttaattc cttgttgaat attatcaagc gtaaccgtac
    17941 gaaatgattt tttcattaat ttaacaaatt catggtctat acggttatat actttctctt
    18001 caccgctata tgctttaatt gtttctattc ctttaagact ttctatgata ctagaattta
    18061 cagctgcacc ggctgccatt tcttccctgt tcgatttttc atagcttttc acgaaagcga
    18121 atattgcaac tacataaaaa ggcaaagagc atagagtgat taaaaacaac gtactattct
    18181 gaatagctaa cgtaacccca acaagcaaca ccataccaat atctaaaaat attgataacg
    18241 tagcacttgc taaagcatca ataatcttac tggcatcaag aaaacgagaa ataatttccc
    18301 ctgattttct cgtagcaaaa aaattcattg gtaaagttaa cacatgtttg aaatactgaa
    18361 gcataattgc catactcatt cgctgtccta aaataataag aagataacta cgactatatt
    18421 caaacaatac ccgaagtaaa tagacagcga tcaagccaat ggaaattata tttaaagttg
    18481 aacgtgcttg attagggatg aaaaaatcaa gaataccttg aaaataatat gagcttccta
    18541 tgccaaaaaa cgtaatgaaa atcgatgcta aaacgatgtg gaatactaat cctttttgtt
    18601 tccaaattat aggcaaaaaa gaacttaatc cagctacttt ttctttaata ggaatataag
    18661 tttctctagg cataggtaat aaaagaatac ctgtccattc tttttgaaac gcttcaatcg
    18721 tttttctatt ttttccatta gcgggatctg caatccatag tacgtttccc ttcgttttat
    18781 aaattacaac gtagtgcata tagctgttat caaccaatat atgtgcaatt aatggtaaga
    18841 taagatctct ttctttccag atctcactat ctgcttgaat agccatacaa tcaaaagaca
    18901 atttttcaaa tgtctttttc aatccaaatg ctgaagtacc ctctaaatca gtcccagata
    18961 ggtcccgtaa tttatgaatc gggatatcag ttttaaaata ttttaaaatc atcgaaaggc
    19021 aagcaacacc acaatctttt tcatcttgtt gctgcacaaa aggaaatgat tttatcactt
    19081 atctaacaca actccttcta aaaaattttt atagaaaaat tctcaatata gctttaatac
    19141 agtgaaaata ttgtctcata attccacaaa aactttgaaa acagttcttg aacactaact
    19201 ttttcattcc tgaatcaaat ttattttgga aattttacta ttcaagaata aacttgataa
    19261 gtttcaggaa gatttttact gttaatcaaa tacgtatgtt acagtagcac cgtaaaaaat
    19321 attatttaaa gaagcgtgtt taaacatgca aaatgtaaag gaactaagta ttgtggaaat
    19381 gcacaaactg ttggtggagg caataatgct tggggaaaat tggggcaagt tgtaggtgga
    19441 cttaccacag gggcagtagg tggtgcaggt ttaggaacag caatttgcgg accagcttgc
    19501 ggtgttgttg gagggttata tggagctgtc gctggaggtg ctgcagctgg ctgggatgct
    19561 cgaaaaaaat aaaaaaggag aataagtagt atgcatatta aaaacacaaa aacaacattt
    19621 atattatctt cagaagagtt gaaaaatatt caaggtggga gtgccgtggg agttttaggc
    19681 actacttttt ctggggcaac agcaggagta aaactttgtt cagccggagg accttatgca
    19741 atagctgctt gtggtgtagg tggagcttta ttaggtgctg gattcagcat gtggaccggt
    19801 gcgtaaacaa ttaaaaaata tcaaacctca agattggttt gtgtcgatta cgaacatagg
    19861 tatgttcttt atcttttcaa aagtttggaa tggacagaac tttttactaa agcttcttgt
    19921 gctagttttt ataattatat taaattttta tcttttatta aagtcagata aaaattcttt
    19981 ggaaatgtaa tggtagagat atttttacaa aaggacttgc agcgctgtag ttggtgctgc
    20041 aggaggacct atttcggccg ttacaggagg tattggtaat gtacttgtcg gatgtgcatt
    20101 aaagcctgtt cctgcaagtt aaatttataa aaacaggaaa gtaattatct caaatcctat
    20161 caagtacaat cataggattg cacttgacag gacaaatttt ttaactaaaa aatgaaaaac
    20221 actttctaaa aattagtaga atttgccaaa tctttcgcat cttccaccat acatttaatt
    20281 ttaattcccc tttatggtac ttaataaaaa caagaaaaga actattcatt tggccctttt
    20341 ttggttccag accatagaaa tattcctcca gtaactaata ttgctgttat gcacgtaact
    20401 aataacagct ataaaaattg gtacaacttt aataggattc agaaaaattt gcactagtga
    20461 aggaatctat tttattagaa aaatgcaatc tccctaaaga aaaaaccact aaacagtgct
    20521 ttctttcaac ttctccttaa ttttttgtgc tttccctaaa gtaaagtttc tggccaactc
    20581 tgaatcaaaa tatagtgaac gttttttaaa atctatttct ttaacgttaa agatatttac
    20641 taaacacgct cgactaattc ttgttaacat aggatatttc ttttcaagct cactaattct
    20701 tccataaaat tcgtactgcc catctttagt acacaatgat aatctatgtg gtaattttga
    20761 agcttctaca aaataaatgt catttatatc aaaagtaaat gtttgagaac ctatggaaaa
    20821 aacaaatgct tgattcgtaa cctgttttgt tgcatctatc ctttcttgcg ctaataacaa
    20881 taactcaaca atctcgtttc gatactcatc tagtgtttga tcttttgtta caaatcctaa
    20941 cgtttcaact cttcttttta ttgttacggg taacatctca tcatgagtag ttgtaaaaat
    21001 gatttttgct tgaacatcat attttctgat tacttctgct aattctatac cgttaacttc
    21061 atgatttaaa tcaatatcta agaaatatat tccttgcttt ggtcggaatt gtttgaggta
    21121 ttttttaact tctaacggac tttgtgtttt caatactatc ttaaatactt tatcgtgaaa
    21181 aagaatgaaa ttatcaataa ttcgttctaa ctgatttaat tgtataattt gatcttcaca
    21241 taatattatt ggataactca taaatcctcc ttccctcaaa acaacaaaat aacttgagta
    21301 gtaaattgat acggatcgtt ttgatagttc acaaacatat tgggattctt tttattgatt
    21361 tcctctatac tagataaacc taacccttga tgtccctttt ttgttgttat tccttttttc
    21421 attagagtat ctatagagag tagtatctct ctacaactat tcgatatcga aatttctatc
    21481 tgtttatcat ctcggtaaat agctagagac agttctctat cttgactctc tatagatgct
    21541 tcaattgcat tatcgagaat aattccaagc accctaatac agtcaaatat tggaacagga
    21601 acttcaataa tagtacttgg acattcgaat ttacaacaaa tcttattgtt atttgcttgg
    21661 tatagcttcg ctatcaacaa acttttcaaa tattcatttt ttatattttt taaataacga
    21721 tattcaaact tattggttag ataagaatta gaatagatct ctaattcttt tatttctttt
    21781 tccaatatcg aatcatggtt ttgattagcg atttctttta aactcagcaa taaattttta
    21841 tagtcatgtc taaatctggc aaatttttct tgatcttttt ccagtgaatc agtatatttt
    21901 tttagataaa ccaattcttt tcttttcaat tgctgttcat attgttctcg ttgcctaata
    21961 gttattctaa taaataaaaa tagaacaaca aacatttgaa tgattaaaaa tattaagaca
    22021 ccaaacacaa aatgatcaaa tacttgatat tgatgagcaa cataagaaac aaataaacca
    22081 attgtaagta aataaatcat gaatatagca gtaagtttag aactggactg ttcaacaatc
    22141 ctatttatag ctaattttct atataaccaa ataaacatca gcaaaaacaa agaatcaagc
    22201 attatctgga atactacata accataccct tttatccctt caaatgaaaa catatacgtc
    22261 ataaccatgg aagtaataat agatctgaaa tcatcaataa gcatacataa tagtaattta
    22321 tttaaaagca ctatattagt tttcttcttt tcctttaata taaaataact tccgattata
    22381 ggtatagctg cggaaacatc agtaaataat tcaacaaaaa aagtgagtgg tatcaataaa
    22441 catacaaaaa gatattttct tttgttaaga tcagtattag tcatataaaa taagagaaaa
    22501 aagaaaaagt ttcccacgaa cattcttaat agataagctt ttgtatcgat agtaatcaag
    22561 agatcccctc ctgattttag gatatcataa aaaaaatttt agttacactt tttaaataat
    22621 gaaaaaacac attccactaa atttgatgcc ggttttcctt gaggttttgt tccagcacct
    22681 cctttaattt ttttaagctc ttgatctgaa cattgtttag catttagtct atttttttct
    22741 tccattacga ttccccctac aaactataaa tacttttatg tcactgattc aatataccta
    22801 tttttctaat caaaaaattt tgagacatat ttaatattat aagtatcatt aaaattgaga
    22861 tttatctcca taatctgctc gatataaacc atttattcca gcagttcttc caatttcact
    22921 caaatttctt attaattcct cttgatattc agtgaatctt attttattag tataagcagt
    22981 aaaatataga taattcacca atctatttat taaaggaccg ggatctaatt catatttttg
    23041 tttttctaat tttaaatata ccttttgtaa aacctcaaga atatcagaat atttaggatc
    23101 tttacttata gatatatcat tatataattc atgaacaatt tgcttagcat tttttttcat
    23161 tttagcactt ccctggaatt gctccaccta aaaaaccacc tatagacatt cctgcaatac
    23221 aagtagttgc cttggcccaa tcgaccgtac atttattttt agtgcaatac actccatttc
    23281 cataatattt tccactatga gtggtacccc catagataag ttgtgtctct ttaatagaca
    23341 aaatttttaa atgtttcata atctaatcac ccctaaatta atgtttttag actattattc
    23401 taacattcat taaatttcaa aaaacaattc cttcttgaaa cgtagcaaaa taattcctga
    23461 ataagaattt aatcactttt aagtatataa actatgtata ttctttaata ttttttgaga
    23521 atgcacttcg tacataataa actttaatca cattagtctt tcatacctac gatcgatctc
    23581 tttgactcgc acccataaat tcataatagt ttgtcggcgt ctttggacgt ttcgaagatg
    23641 agctacgcat tctctttttt tatagacaaa aaagatagag acgaacatgg agcttccaaa
    23701 tttggatatt tgatccaatt ttggaagctc catttatttc gtgtctgtct ttttattttt
    23761 tccagctttc gactaattct tggttctctt tgatccagtc ttttgctgct tgctgtggat
    23821 cttttccatt gttgatttcc aacataactt tttccatatc tttttctgac caatggaaat
    23881 tgtctaatac tttgtaagct tctggctggt cttctttcaa tccttttcga accatcgtat
    23941 ggatctgctc ttcgcttccc attccgtttt caggatcttc taagtatttc agatcatatt
    24001 tggcaaacat ccaatgaggt gtccatcctg taactacaat tggttcgtgt tttttgatcg
    24061 cttgacctag tgcaacggtc attgctcctg aagaagatgt ctctactttc cagtctttca
    24121 agttgtcata tttttggatc gtgttttcag cagccgtaac tacaccagct cctggctcga
    24181 ttcctatgat tttcttacct gcctgatcgg ttaactcatc gatcgaattt acatccatgt
    24241 aggctggcac tgctaaacca acttttgctc ctgtcaaatt ggcacctagg tcttcgactt
    24301 gatctttata ttgtgcatat tgtgaaccat gagttttagg tagccaagct gaaaccatgg
    24361 catctgactc gccatttgaa acagatttcc acatgattga attatctaat ggcgtcatcg
    24421 ttacatcata gcccatttgt ttcaatactt caccgactac atttgttgaa gcaacttctg
    24481 tatcccattc aacataagat aagttgatac gttttgtttc tttggcagat gaaaaactcc
    24541 ctataccaat cgcacctaag atcactacta ctacagcacc aatgatcagt ccttgacgtt
    24601 ttttactttt ctgtgttgtt gctcctgcag cttttttatt gtttggctgg ttcaaatgct
    24661 gtgtaaaacg gtcaatgatg attgctaaga taactaatgc aaccccgttg acaaatccat
    24721 tcccgacttg tgctctttgc aatgctgata atacgccgcg tcctaagccg ggtgcaccga
    24781 tcatagaggc aataacgacc attgaaagtg acagcattgt tgtttgattg atccctgcca
    24841 tgatcgtact tttagctaaa ggcaattcta gtttgaatag tttttgacga cttgtgctcc
    24901 cgaatgaatc agaagcttct actaattctt taggaacttg tcgaatccct aaattcgtaa
    24961 aacgaacggt tggtggcaga gcaaagatga ctgaggcaaa tacccctgga accatcccga
    25021 taccgaaaaa tgcaactgct ggaatcaaat aaacgaatcc tggcattgtc tgcataaagt
    25081 caaggatcgg tttgataata ctttgggctt tactgctttt tgccatcaag atccctaatg
    25141 gtaccccaat gatgatcgag atcacactag ataaaagaac aagtgtgaca gtattcatca
    25201 aatcattcca tagaccttgg ttataaataa accatagacc gattaatgtg aacaacgtaa
    25261 gtcctggacg tttcttagaa ataaagaaag ctgctaccgt caataacaag ataaacaaag
    25321 gagctggaat cactaacagt aaatttgtaa tccccgacat cactgcctgt ccaatcgttt
    25381 gtaaaaatga aaataggcca gaaaaagttg tcgtaaacca ttctgtgata ttttctaccc
    25441 agtttgccac tggtaattga tagttcaata gattattcat gttcactcac ctcgcttgtt
    25501 tctgctaatg cttcaatcac actacctcgg atgacgacac cttttaattt tccatcctct
    25561 acaactgcaa gtggagtcgg tgagtcataa ataatattga aaatatcact taccaccatg
    25621 tctttcccaa tcaccgtcac attttcatct aggaagtcga tcaatggacg tttttgcttc
    25681 ctagcttcta acgcttgatc tgcagtgatg atccctttca ggtgtctctt tctgtcaaca
    25741 gccatcagca tgctgacttc ttcattacgc atccttgtca atgcaacgtt tggtccatca
    25801 gattcgatat tcgtcgtcaa tgcaggtacc atgatgtttt gagccgtaag cactttggaa
    25861 cgatcgactt cttccacaaa ttcacgtaca taatcatttg ctggattggt caatatttct
    25921 tcacctgttc cgatctgcat gatttcgccg tctttcatca aggcgattct gtccccaatc
    25981 cgtaaagctt cattcaaatc atgggtaatg aaaataatcg ttttttgaac attggcttgc
    26041 aggtccagta attcgtcttg catttctcgc cggatcagcg gatcaagagc cgagaacgct
    26101 tcgtccatca gcaagatctc aggatcattt gctaaagctc tggctaggcc aacccgttgt
    26161 tgcatcccac cagataactg actaggatat tggtctttaa atgaaagcaa actagaattt
    26221 tctaatgctt tttctgcttt ttcttgtcgt tcttctttag gtacaccacg gacttctaac
    26281 ccgtattctg tattttccaa gatcgttcga tgtggaaaca gaccgaagtt ttggaaaacc
    26341 atattgattt tatgacgacg gacttctcgc aattcttctt tgcttaactt cgatacatct
    26401 tctccatcaa tatagatact gcccgaagtt ggctcaatca gacgattcaa tagacggatc
    26461 aatgtggatt tcccactccc ggaaagcccc atgatcacga agatttctcc ttcttttacg
    26521 tcaaaattca cgtcatacac accaaccgtt gcaccggttt tctttaaaat ctccgttttc
    26581 ggctggtgat cattcatcat atctaaagcg gcttgtgtct ttttaccaaa tatctttgtt
    26641 aaatgtttta cttctacttt taccaaacaa attctccttt tttatgtaaa ttcatttttc
    26701 tttctgaaaa aagtgaccac actatgttaa catcatgtag tcactttgtc aaaaatgaaa
    26761 gaaatttgct tgtccaaact gaaaaaaact tggctaaatc tttgtaaata aaaggtttag
    26821 ccaagttaat atttttttaa tatttcacac aatcattctg caagctgatg ctccgggtaa
    26881 aaaaagtttg tcatacgctg tagtgtatat tcatttccaa taaaatgaac gatgtcccct
    26941 gccgtaaatt tagcataggg gccaggtgaa acaagcagtt cttcattatg agaaattgcg
    27001 ataactgtgg cgccagtcgc ctgccagata ttcaactcgc taattgaacg gtccagatgc
    27061 attgcttttt ctgataaaga taattcaaac ggaagtaaag gattcatctt atgtattcgc
    27121 ttcgtttgat tgaccagctg atccaataat tgagaaaaat gattcagctc atcttgttgc
    27181 ttctccacac ttgccatgat ttctgctttt gtatcttgga tggattgtac atcttgatat
    27241 tgcaatagga aatcttttgc tttttccttc gaagcaacaa atgccccact tccatgccgt
    27301 acttccatga ttccaagatc taccagcaca ttgatagcct tgcgggtagt ctcaggagaa
    27361 gcattgtacg tactggcaag tgttgagcgg gcatggatct tctcacccac tttatatcgg
    27421 ttttcaacga tacgttcggc taaatcaaca gcaatctgct ggtagcgcgg gcggacgatt
    27481 tttttctttc cagacatttt ctttcctctt tcttttttta ctttccctca tcttactatg
    27541 ctctagcaaa ataagcaaaa aaggggagaa tagcctcttg caacgactga tcatcgcttg
    27601 atctgttcct tttttactgg gcaagctgtt tgacagtcat cacaattctt accggatttt
    27661 aaacgagtat agacaattgc gcctgcactt ccaaagatta acacacttaa taagaatgtc
    27721 gccatcctat tcctctcctt ctaatgacaa tatagtataa aactggttct tggattttgg
    27781 ctgacggaac aaaacataaa cgagtcctat catcagtaaa atagcaagat acgtccctaa
    27841 cgctacctgt ccaccctcca ataagtgtcc caactgataa atcacaaaac taactaaata
    27901 agctaaaccg cattgatagc ctatggcgat ccaagtccat ttcttggcat tcatttcccg
    27961 atggatagcc ccaattgccg caaaacaagg cgcacaaagt aaattgaagg ctaacaatga
    28021 ataagctgct gcgggagtat atgtgtgttg tagcacttgc cagatttctc tgccattttc
    28081 ggatacttcc gcatgaccaa acaaaatacc aaatgtgcca ataatatttt ctttagcgac
    28141 caatcctgta atcgctgcga ctgttccttg ccagtttccc caaccaagcg gctgaaaaac
    28201 aactgccagg attcgcccga aaaaggctaa gatactttgg tcttcagaaa caggttgagc
    28261 ataaaaatta taagaagagc tgaaccagat cacgatacta gaaacaaaga taatcgttcc
    28321 tgctttttta acaaaagact tgctgcggtc ataggtttgt cttaggaccg ctgaccattg
    28381 aggaaaatga tatgcgggca attccatgat aaaaggagct gtatctccag caaacaaacg
    28441 tgtttttttc aagctgattc cagagaaaat aattgcagtc ataccaagaa aataggcaga
    28501 aggagctacc caagattgat gaggaaaaaa ggcccctgct actaaggcaa taatcggcaa
    28561 ctttgcagaa caaggcatga aggttgtgac catgatcgtc aaacgacgat cttgctcgtt
    28621 ttcaatcgtg cgactggcca tgacgcctgg cactccacat cctgtagcaa tcagcatagg
    28681 aatgaaggat tttcctgaaa gaccgaattt cctgaaaagt cgatccatga caaaagcgat
    28741 cctcgccata tatccgcagt cttccagaaa gctcaagcat aaaaacaata taatcaattg
    28801 cggtagaaat cctaacactg ctcccacgcc tgcgatgatg ccgttcaaga tcagctcctg
    28861 catccatccc gctacttgcc attcagctaa caatctgcca acatgttctg gtaaccatgt
    28921 accaaacaat gtgtcattga tccaatctgt ccccattgtt cctactgttt gaatagccag
    28981 ataatagatc agccacatca caaatgcgaa gatcggcaag gctaaccaac gattcgttgc
    29041 aatctgatcg attttgtcac tcatcgataa ttggaaagaa tcatttgaca caacacagag
    29101 tgtacatagt tgggtaataa attcataacg ttcattgacc agaatcgtct cactatcgtc
    29161 gtccaatagt ttctctgtta actggatcag ttgctcgatc tctttttgct gagaaactgc
    29221 tatctcgtaa tcctctctta ccttctgatc tcgttcaaaa tatttcattg cataccagcg
    29281 tttcttgccg ctttgttctc ctagtacatc ttcaatttca tgtaaagctg cttctaaacg
    29341 tggatcatat gtacagggaa caggaataga aggccgcttt tttgcagact cctgaatctt
    29401 ttcgattagt ttttcgattc cttgcttttt caatacgctg attggtaaaa ctggtacacc
    29461 aagaccatag gaaagctttt ctagattgat tttttttcct tcttttttga tgacatccat
    29521 catattcaga ccaatgatca taggaatgtc taaatccaat aactgcgtag ttaaataaag
    29581 atttcgttct aaattggtag catcaataat gttgatgatc agttcaggct gttcctgaac
    29641 caaataatct cttgcaatca cttcttctgg tgtataagga gacaaagaat agatgccggg
    29701 taggtcctga atatgaatgt tcggattttt tttcaacgat ccttcttttt tttctactgt
    29761 tacgcccggc caattcccta catattgatt cgaaccagtc aagagattga acaagctagt
    29821 tttcccgctg tttggatttc cgactaacgc gatattcatt ctttttcctc cctttgtatc
    29881 aagattagtt cggcctctga ctttcgtaac gtcagttcat accctcgcac tgtcagttcg
    29941 attggatctc ccagaggggc tagttttcgg ataactattt ttacatttcg cgtcaatccc
    30001 atatccatta accgtcgctt cactgcgcct tgtccgtgga ttgctacgac gatcccagtc
    30061 tctcctgctt ttaattgatc aagagaagtc cagctttcag aggaagcagt ctttttattg
    30121 acaaagattt gacctagtat ttcccgactt actgccactc gatgactttt taccagtaaa
    30181 atggcattgt tgcctgataa attgacgacg acgattttac ttccggcaac gatcccgata
    30241 ttttgcaaat ggcgttttgt tttttcttct gtttcgattc gttcgacttg ataaacgaaa
    30301 ttctgctttg cctgcgctaa ggtctgcata ttgattcctc tcttgtgaaa taaatcatgt
    30361 attaaaatca ttcattatat gttctaattt tcttacgtgt tacgcaaata aatgagaatc
    30421 attctcacat agaatactct cggtaattga gaatgtcaat tatacttgtg atattatgag
    30481 cgaatcttta gtattgatag ataaaaatga gaaaaaaata tttcttcata gttttccaca
    30541 attttttctc tattaaattt gctattttcc cacacgatac ttgttttcag ctcttttttc
    30601 aaaaacacaa aacttagtat tccacagttt ccacaacaca atatgtagtg tttgttgttt
    30661 gactttttta ctaagagttt tatactatct attatagata ataagaatgt gttagaggag
    30721 gcactcacca tgaacgtaaa aatcttttct aaaaataatt gtatgcaatg taagatggtc
    30781 aaacggtttt taacagaaaa tcaaattgct tttgaagaag tcaatatcga tgaacagcct
    30841 gaagcagtag actggttgaa agcacaagga ttccaaagtg ttcctgtcat tacttctgat
    30901 gcagaaacag ttatcggatt ccgtcctgat cagttgcgta aacttgccag ctaacatgac
    30961 taaaagaatc aaaacgtgat acatggattt gaagggcttg agacagcacc agtttttgtc
    31021 gcaaacttcc aaatcctttt ttaaagctta aaaacaatgc aatgatttgc aatcaagcat
    31081 catcaaatac gaaatgaagg ttgggcgtac gtatgagtct taaaaattta caagatgtca
    31141 gttatttcaa gctgaataat gaaatcaatc ggccagtcaa tggtcaaatc cctttgaata
    31201 aggataaaga agctttagtt gccttttttg aggaaaatgt caaaccaaat acgatgactt
    31261 ttctatctat tatggaaaaa atcaattact tgatcgatca agaatatata gaagcagaat
    31321 tcattcaatt gtattcacca tcatttattg aaaagctata tcaatttttg gacgagcaac
    31381 atttttcttt caaatctttt atggctgctt acaaatttta ttctcaatat gcgttgaaaa
    31441 ccaacgacgg ttccgcttat ctggaaactt atgaagatcg agtagccttc aatgcgcttt
    31501 actttgcgaa cggggatgaa gaattagcac ttgctcttgc agacgaaatg atccatcaac
    31561 gatatcagcc agctacacct tctttcttga atgctggacg taaacgtcgg ggcgaattgg
    31621 tgtcttgttt cttgactcaa gtcactgacg atatgaactc tatcgggcgc tcaatcaact
    31681 ctgctttgca attgtcccgt attggtggcg gcgtagggat tactttatca aatcttcgtg
    31741 aagccggcgc tcctatcaaa ggatatgagg gtgctgcaag tggtgtcgtt ccagtcatga
    31801 aattattcga agatagtttc agctattcta atcaattagg tcagcgtcaa ggagctggcg
    31861 tggtttattt gaacgttttc catccagaca ttattgcttt cctttcagca aaaaaagaaa
    31921 atgcagatga aaagattcgc gtaaaaactc tttctcttgg cgtgatcgta cctgataaat
    31981 tttatgaatt gacacgtaaa aacgaagata tgtatttatt tagtccatat agtgtcgaaa
    32041 aagaatatgg tgtcccattc tcttatgtaa atattacagc tgagtatgat catctagttg
    32101 caaatccaaa cattcgcaaa caaaaaatca aagcgcgtga tcttgaaaat gaaatctcaa
    32161 aattacaaca agaatctggc tatccttacg taatcaatat tgatacagcg aaccgcgaga
    32221 atccaatcga tggcaagatc atcatgagta atttatgttc agagatttta caagttcaaa
    32281 cgccttctgt gattaacggc aaacaggaat atgaagtatt aggaacggat atctcatgta
    32341 acttaggctc gacaaatatc gtgaatttga tgcaaagccc taactttggt caatctgtgc
    32401 gtacgatgac tcgtgcattg acatttatta cagatgcatc tgatatcgat gtcgtaccac
    32461 cgatccaaaa cggaaataag ctgaatcata cgattggatt aggtgccatg ggcttacaca
    32521 cttatcttgc aaaagaacaa atggaatatg gctcagagga ttcattagac tttacaaata
    32581 tttacttcat gctgttgaat tattggacac ttgttgaaag caacaatatc gctcgtgaaa
    32641 gaaaacaagt tttccataat tttgaaaaat cagcttatgc tgacggcact tatttcgaaa
    32701 aatacgtaac tggagaattc cagccaaaat cagaaaaagt caaagcattg tttgaaggca
    32761 tttttatccc aactgctgaa gattggaatg ctttgaaaca agcagtaatg aaagatggac
    32821 tgtatcatca aaatcgcttg gcagtagcac caaatggctc aatttcatat atcaacgata
    32881 cgagtgcaag tattcatcct atcactcgca tgatcgaaga acgccaagag aagaaaatcg
    32941 gtaaaattta ttacccagcg ccttatctat ccaatgagac gattccgtat tacacttctg
    33001 cttatgatat ggacatgcgt aaagtaatcg atgtttatgc aatggcacaa caacacgtcg
    33061 atcaaggcat gagtttgact ttattcatgc gttctgaaat cccagaaggc atttatgaat
    33121 ggaagacaac aacgaagcaa acgacacgtg atttgaatat tttaagacat tacgctttcc
    33181 acaaaggaat caaatccatt tattacgtac gtacctttac tgatgatgca gaagaaatcg
    33241 gaagcaatca atgtgaaagc tgcgtgatct aatatcatag atagattcgc ttattcatat
    33301 tttaattaaa ggagcattct catgtcagaa acatattatg aagcaataaa ctggaatgaa
    33361 attgaagata tcattgataa atccacttgg gagaagctga cagagcaatt ttggctagat
    33421 acacgtatcc cactttcaaa tgacctagat gattggcgta cattgtctca attggaaaaa
    33481 gatacagtag gacatgtatt tggcggtttg acactgctag atactgtcca atctgaaagt
    33541 ggcatggatc agttgcgtaa agatgtccgc actccccatg aagaagccgt tttgaacaat
    33601 attcaattca tggaatccgt tcatgccaaa agttattctt ctatttttag tacactgaat
    33661 acgaaaaaag aaatcgaaga aatttttgac tggacaaata cgaatcctta tctgcaaaaa
    33721 aaagctgagc gtatcaatga aatctacaaa cacggtacac cgctagaaaa gaaaattgcc
    33781 agcgtctttt tagaaacatt cttgttctat tcaggttttt atactcctct ttattattta
    33841 ggaaacaaca aattggctaa cgtagcagag atcatcaaac taatcatccg agatgaatct
    33901 gtacatggaa cctacatcgg ttacaaattc caattaggat tcaacgagtt acctgaagca
    33961 gaacaagaaa cgttaaaaga ctggatgtac aatcttcttt atgagcttta cgaaaacgaa
    34021 gaacgttata cagaagaatt atacgatcca atcggctgga cagaagaagt caagacattc
    34081 ctacgctata atgccaacaa agcattgatg aacctaggga tggatccact ctttccagat
    34141 actgccaatg atgtcaaccc aatcgtaatg aacgggattt caacaggcac aagcaaccat
    34201 gacttcttct cacaagtcgg aaacggctat ttgttaggtc atgtagaagc gatgaaagac
    34261 gacgattatt tgattggatt ggaataagga tttattttaa ttcaaaaatt tttcgaaaaa
    34321 taaaaagagt ttagcgtaca gatattttaa atgtacactg aactcttttt tatgcttatt
    34381 cacttgtttc ttccagcact tttggactgt ctaacttttc cgaaacatgt tccattcttc
    34441 tcaataaata gattttccgg atatttaata ttatcgtctt aatcactgca tagacaggta
    34501 tgcaaatcag catgcctaat attcctgcga cacttcctgc tccaatcaat accaagatga
    34561 tcgtcaaagg atggatattc attgatttcc caaataacaa cggcttgatc aaatttccat
    34621 ctaattgttg gatcactaaa atcgacaacg ccatatacaa agcttgaaat ggagagataa
    34681 acaaaccgac aatgattgct ggtaccgctc caataaaagg gccgacatac gggataatat
    34741 tcgtgattcc gcaaatgacc gcaagcaaca agctataagg ctgatcgaat attctcattg
    34801 ccaaaaagct cattacacca ataatcaaag catctaagat cgtactgctg atataggcag
    34861 ataatgtttc gtttaattct tttaccgttt ggcgtaactc tttacgaatc gctttcggaa
    34921 agaagtgaga caacgcatca ataaatttgt gcccatcctt gaacataaat agcaaaataa
    34981 atggaacggt aaataacaaa ataaaaaatt gcatcataaa tgaaatgatt tttgagacac
    35041 ttgcagataa actgactaat atgatattga acaaattact aagagataaa tttgctgatg
    35101 ctaattgttc ttccaaattg aaatttttaa actcttcccg ctgcgccaat tcatttaacc
    35161 atttgcttgt ttcatctgca tacattggca agctctgggt caattgaatt gtctgttcca
    35221 ttaactgagg cactacattc atgacagtta aaacaactaa aatgattacg accaaaaacg
    35281 tcaataaaaa accgaacact ctcgggatcc gatgcttttc gagaaaaaca acgattggat
    35341 cgaacatata atagataaaa ccagcaacaa gcaatggtaa aaaaactgcc gaaagcattt
    35401 tcaatattgg actaaaaata ttcggcattt gtaaaataaa gtacacgccg atgatcgtga
    35461 gtactagctc cactgtccag aaaaataatt ttgattgttt aaaacgtgat tgcatacatc
    35521 tcctccaagg tcctttgata cttctattct atcatttaac aaagagttac gcgctgagat
    35581 tttcatttgc ttaaaaaaaa caaaaaaaat aaacatattt taatgagtag acgagtactt
    35641 aaacaaaaac acggtttgga gtagtgacaa aaattatact gcagtccctt tttccaaata
    35701 aacggtgttc aaaagcttgc atcttcgtaa taagcccagc caaacgaaaa atataaggaa
    35761 ctatttttat ttggctgggc ttattacttg atgtaggaca tctattttac aacctcagat
    35821 catttattgc gcaatactga ctaaatgcaa ctttgtgata tttttgtgta cggacaactc
    35881 ctcgatcaca tcggcataag tgagcccttt tggaagatca atcgtataga tatttttgta
    35941 cactcggtag tcatcaacga attttacgtc aaaattcaca tcttcgatta cgatattttt
    36001 ctcttcaaaa taatcggtaa gaaaatcttt ggtttctttt ctatggataa attggatttc
    36061 taacttttta gtcgtaggta catggatcac gcgtttcact actgtgagtg caatagcaat
    36121 cccgataaaa ctgatgatcg caatggaata gtaacccatg ccgatggcga tccctaatcc
    36181 agcaattgcc cataaagaag cggcagtcgt aagtcccgtc accgattgtt tcgtgacgat
    36241 gatcgttccc gcgcctaaga aaccgacacc actcaccact tgagcaatca gccttgcttc
    36301 atctgaacga atcgttccag caagctgtgg atactctaaa gcatctctta atgcaccact
    36361 agcgatctca acttggatca atgcaatgat acatgctccc atacaaacta aaatatgcgt
    36421 acgcatacct gctggacgat ttttatattg tcgttcaaaa ccgattgctc cgccaaatag
    36481 catagcgatc cctaaacgta aaataatctc tggaattgtc aataccatat cattcatcta
    36541 aacaccctcc agtccaatat atcatgtctg aaaggagcag acaaaaaaag tgcaattttt
    36601 acctcttacg aaaaaaggac tgtgacaaaa tttttgtcat agtccttttt atgaataaac
    36661 ggtgttcaat cagctgaccc tcggtattac tcaacaaacg gcaaaatatg gggagctatt
    36721 tttcctttgt cttctctaat actcaggtca aaacgctgat ttcacaacct ctttagccta
    36781 ctattgaaaa ttacaactta cttgctgctt cttcatcgat gatcacaaca acattgtcgt
    36841 gattttgcaa tacacttgct ggcaaatgat tcgttacagg tccttcaatc atccctttga
    36901 ttgcatcagc tttgctttcg ccaaatgcca tcaagacgat ttctttactt ttcataattg
    36961 aaccgattcc cattgaaaca gcttttgttg gtacatcttc tgctttatcg aagaatcgtt
    37021 tgtttgcatt gattgttgat tctgttaagt caactactga agtcgttccg tcaaatgaag
    37081 caccaggttc attgaaaccg atatgtccat tttgcccgat tcctaagatt tggatatcga
    37141 ttggatgtgc atcgatgatt tgatcatact ttttgcatgc tgcttccaga tcttctgctt
    37201 ttccatctgg tacaaacgtt tctttgaatg gttttttatc aaataattgg acatccatga
    37261 aatgacggta gctttgttca tctgaaccgc ctagtccaac gtactcatct aagtttacag
    37321 aagtcatttc actgaaatcc aaatcgcttg aagtcatttc tttatataaa gtaactggtg
    37381 tgcttcctgt tgccaatcct aatacttttg cacctttgtt cataccttct ttgatgattt
    37441 caaatgcttt ttttccgcct tcttcagcgt tttttacacg aatgatttcc atagtgattg
    37501 ctcctttata ttttggtata gcccaattat agcattcttt ttttcttttt acaataatta
    37561 gtatagacca aattgcattt ttttcatttt cttgacaata aataggaatc cgtgttaggt
    37621 ttcataagat ggttcaatca aacaatccat gttgcatgaa aaccaagcaa gtgattcact
    37681 gtggacgctt tatgtctgca gtttttttat gaaaaaggag ttattatgag tatactgaca
    37741 ttaaacaaca ttacccagca atttggcgac aaaatcctct atgaaggtgt cgatctgcaa
    37801 ttaaatgctg gcgaacatct tgggctgatt ggacaaaacg gagccggtaa aagtacattg
    37861 attaaaatca tcactggtga gatcttacca gatgacggac agatccattg gcaaaaaaat
    37921 attcacaaag gttacctcga tcaatatgtg gaagtcgatg aaacattaac aatcgaagaa
    37981 tttctaaaaa ctgcgtacgc aaaagaatac gaaaaggaag aaaaaattgc ttttctttac
    38041 caaacatata gcgagacctt cgatgattcc ttgctggaaa aagctgggaa actccaaacg
    38101 gaattagacc aaggagtgtt ttatcaaatc gacaccttag ttgctgagat gagcagcggg
    38161 ttggggatcg atgtcttagg tttagattca ctgttgaaaa atctaagtgg tggacaacgt
    38221 tcaaaggtga ttttagcaaa actactttta gaaaacccag atgttctgat cttagatgaa
    38281 ccaaccaatc acttagatga tcagcatatc caatggctga cgcagtttct tcaggatttt
    38341 gacggtgcgt atatcgtgat ttcccatgac caagaatttc ttgatcagat caccacccat
    38401 atcgcagaca tcgagtttgg aaagattact aagtatactg gccatctaaa acaagcattg
    38461 aaacaaaagg aacaaaatcg cgaaagctat ttgcgccaat atcatgctca acaaaaacaa
    38521 atcgaaaaga ccgaagctta tattcgaaaa tacaaagccg gttcccgatc aacgatggca
    38581 aaaagccgac aaaaacaatt agataaaatc gaacggctga cgcctccagc ttcagcaagt
    38641 aaagctgtct ttgattttcc attctcgcct attgtcacga cattagcagt ggaaacaact
    38701 gatttagtca tcggatatga tcgaccgcta cttgcaccca tcaatttgac catccgcttt
    38761 ggtgaaaata ttgccattcg aggcttcaac gggattggaa aatctacttt attaaaaaca
    38821 ctgatcggtg agattgaaaa aataagtggc gatttccact tcccagataa cacaaaaatc
    38881 aattactttt cacaagatct gtactgggaa aatccattag aaacaccact acaatattta
    38941 agcagtcaat ttccaaaagc gactatcaaa gaattacgtc gccaactagc taaagcaggg
    39001 ttagttaatc aattagcaag tgaacctctc actacattaa gtggtgggga acaaactaag
    39061 gtgaaacttg cacagttgac aatgaaccaa ggtaatttac tgattctcga tgaaccgacg
    39121 aaccatatcg atcaagaaac gaaagaaagc ttacaagacg ggatacagaa atttccagga
    39181 acagtaatca tcgtctctca tgaacaagaa ttttatcaag atcttgtgca acgagtcatt
    39241 gagattgaac caaaataaac gtttgattga atagttgaaa aaaaggagct gtgacaaaag
    39301 ttttgtcaca actccttctt ctgaataaat ggtggccaat tagctgacct tcggtattag
    39361 ctcaaaaaac ggcaaaatat gaggagctat ttttatttgg ctattcttat tacttgatgc
    39421 agaacagctt ttcacaacct cttttcgtct attttttatt ttcgagattt ctctttcctt
    39481 taaaaacaac tgtttgaaag aagaacgcac atccttgaaa aacaagcccg ctaaccgtta
    39541 cacctaacca gccatactgc tgccacattg tcgtccctag caatgaacca gccgcacctc
    39601 caataaagta cataaacata aatacagtat tatttcggtt gcttgctgct tcacctagcc
    39661 cttgtactcg tgtttgattg gcgacttgac caaattgatt cccgacgtct aataaaataa
    39721 tagctaaaag caaaatggcc aaatggcttc cgccaaccaa taaagcaata aagcttattg
    39781 tttgcataac aagtcccata tacacgattt ttctttcaga ataagaatct gccagtcgtc
    39841 ccacgatagg tgcagcaact gctccagaca aaccaaaaat cgctaatatc cctgcttcga
    39901 atgttcccca attgtaggcg ggactgctga tataaaaaat caacgtagac caaaagatcg
    39961 aaaatgttcc aaacatgaaa aatccactga ctgccgcttc tcttaataga cgttgagaag
    40021 caactaaatg cggcaaactt ttaagtgaat caaggtatga aacagctgta ctactttgct
    40081 ggacagaacg cggcattttc cagtaaagca gaagtgtaag aattccgact gcacataaag
    40141 caaataaata gatcatccgc caagaaaaaa gactggcaac aataccagat accgtccgag
    40201 aaagcaaaat ccccacgagt aaaccgctaa gcaatgtacc catgaccttc cctcttgctt
    40261 ttggtcccgc tagtaccgca ccgtaaggaa tgatgatttg cggcacgatc gaaagtaatc
    40321 ctattaaaaa agaagcgcat gcaaataacg taaacgaagg cgcaaaaaaa gcggccaaca
    40381 gagagacggc agataacgct gccattcgaa tgatcaattt tggacgatcc accacgtccc
    40441 ctaaaggaac taaaaacagt aaccctaacg catagcctaa ttgggtcaac atcgtcaata
    40501 tcccgactgc acttgtgcta acagataaac tagctgctac ttttgttcca atcggctgga
    40561 tgtaatacat attggcaaca acaacgccac aagtgattga taatagtaaa ataagcgaag
    40621 ttgttaaagg ttttttttca ttactcttca ttgatttccc ccatttccta tcttagttta
    40681 caacttatgg aaaagattgg aaatagaaaa atacaactat tcgccacact tattatttgt
    40741 gcttttgttt tccttgtttt ttcttgcgat ctttataaat gaagacaact aaccctacta
    40801 gcacagtaac acttgcaacc aacgtgactg cagttttgtt atatccgtga aacagagctt
    40861 ctccaccaca cgcatacaac acagacgaag ggatgactcc aatcacgatc gacaatatga
    40921 tttgctgtag aggcaatttc atcgcatctg cagcaaaatt gaccatagaa gatggaataa
    40981 ccggtatcat atagcctaac attacaccta tttttggatg tttcatttgt cggattgctt
    41041 gcacccaatg attcgtttcg gttttcttat ctaaaaattt taagcgatgc ataaggaaaa
    41101 ttgcagtgat gttaccaaga gcattaccca aaatgttgat gatcgcacct gtcagtggtc
    41161 caaagctcaa accagcaatg actccaacta ctgaagtagg aatacctgga acagcacaca
    41221 tcaccgctgt caatacgatc aagagtatcg atgcaaaagt cccatgcgaa cgaatatgtg
    41281 cgagtagctc tgccttactc gctctcggat ttaaaaataa ttggatgtct gtctgatatt
    41341 ctaaatacaa ccgatagccc actaccagta tcagaatgat tcccaacgag atcaatatca
    41401 atcggattat tttctttttc atatttcctc ctgaaaaaaa tctatattca ttaaataata
    41461 gtttaacata aaaacaaaaa agcaccgaaa tccaacatag gatctcagtg cttttaaata
    41521 gtaaaaatta tttaacagtt acagatgcgc caacttcttc aagtttagct ttcaattctt
    41581 cagcttcttc tttagatacg ccttctttaa ctggtgcagg agcgccatca actacagctt
    41641 tagcttcttt caagcctaaa ccagttgctt cacgaactgc tttgataact ttaacttttt
    41701 ggtctccagc tgcagttaat tctacagtga attctgtttg ttcttcagca gcagcagcgc
    41761 caccagcagc agctacagct acaggagcag cagcagatac gccaaattct tcttcaatag
    41821 ctttaactag gtcgttaagt tctaggatag ttgcttcttt taactcagca acgatgtttt
    41881 caatgttcaa tgccattata atttcctccg tttaattgtt cttttttatt taatgcttta
    41941 tgcggcaatt aagctgcatc tccatcttct ttgtctgcca ctgctttgac agcgtaagcc
    42001 acgttgcgga ctggcgcttg tagtacagat agcaacatag atagaagtcc ttcgcgattt
    42061 ggcaattttg ccaatgctgt gatttcttcc aatgaagaga ctttaccttc gatgataccg
    42121 cctttgattt ctaatgcttt tgcttcttta gcaaattcgt ccatgatttt cgctggtgcg
    42181 actacatctt cgttactgaa tgcaacagct gtaggtccag tgaatacttc gtccatgcct
    42241 tcaaggccag cttttttagc tgcacgtgaa agaatagaat ttttgataac tttcatttct
    42301 acgttagcat cacgaagttg tttacgtaaa cgtgttactt catcaactgt taatccgcgg
    42361 tagtcaacga ctactactga tgcagctgct gtaaattttt cgcttacttc atcaacgatt
    42421 gctgcttttt ttgcgataat tgcttcactc atttttgagt ttcacctcct gaattttgat
    42481 ggaagagttt tttgcactga aaaggcaagt cacttttata gttactttgc tcaaccagta
    42541 ttattcatca cctattcact tcgttcatag tgattctact cgctttgctc gaaaggaaac
    42601 tcctttcgct ttgctcaacc agtattgttc atcatctctt cacttcgttc atagtgattc
    42661 acaataaaaa actctatgcc accgcagaca tagagggact attgaatata ttcaataaac
    42721 gtcctcggta ggaaattaag gcttgatgcc acctactgtc ttcggtacaa gttaattatt
    42781 aacctcaact agcttagcat gctaaactag ttgagtcaag aattattttt cagttggatc
    42841 aatcaacatt ctaatattta attagaaaga agcttggtca acatggatac caggtccaaa
    42901 tgttgttgtg atcgttacat ttttcatgta ttgaccttta gctgctgatg gtttagcttt
    42961 tagcaataca tcatggattg ctgcaaagtt ttcaactaat ttttcatcgt caaatgaaac
    43021 ttttccgatt ggtacatgga tatttccagc tttgtccaca cggtaagtta ctttaccagc
    43081 tttcacttcg tttactgctt ttgttacgtc cattgtaact gtaccagttt tagggtttgg
    43141 cattaagcct tttggtccta atactcgtcc tagacgacct acagtagcca tcatatcagg
    43201 tgttgcaaca actacatcaa agtcaaacca tccgttttgg attttttgaa ccatgtcgtc
    43261 gtcacctacg aaatctgcac cagctgcttc agcttctttt gctttgtctc ctttagcaaa
    43321 aactaaaaca gtttgtgttt taccagttcc gtttggtaat acaacagcac cacggatttg
    43381 ttggtctgct tttttagggt ctacgttcaa acggtatgca acttcaactg ttgcatcaaa
    43441 ttttgcaatg tttgtttctt ttgctaaagc tactgcttcg gcaacaggat aaactttact
    43501 tgaatcaact ttttttaatg catcttgcat ttttttgctc tttttagcca ttttggttcc
    43561 tccttgattg tggttataac ggttgtacct cccacgtgtt ctatatcttt caatatagag
    43621 ccaactgaga agctgctgtc ttagggtgta tagattattc tacagtgatc cccatgcttc
    43681 gtgcagttcc ttcaaccatg cgcattgctg cttcaacgtt agctgcgttt aggtcttcca
    43741 tttttaattc agcgatttct cttacttgat cgctagaaac tttcgcaact ttatttttgt
    43801 ttggttcgcc tgaacctttt tcgattttag ctgctttttt caatagaaca gcagctggcg
    43861 gtgtttttgt aacgaatgtg aatgaacggt cttcgtatac agaaataaca accggaatga
    43921 tcaaacctgc ttgatcagct gtacgagcgt tgaattcttt tgtgaatccc atgatattga
    43981 tacccgcttg acctagtgca ggacctactg gtggagctgg agttgcttta cctgcaggaa
    44041 tttgcaattt aacgattttt tctactttct ttgccacgag acatacctcc ttaagtccgt
    44101 gatgtggtta attggagatg catatttctc ctcccacgtt ttatctgatc tgaaaaaatc
    44161 cagacaaata atgtgcaaaa caatgcacac tggtacagta tagcaaattt atttgttttt
    44221 tcaagatttt tttctgctat ttttacattt tgcttgaata aacgctaaat ttattctaaa
    44281 aaaacaacaa tttttcgttc tcatttcttc ttttatgtta cacttgcgct agcatggttc
    44341 aacagatgaa agcaaacaat aacacggttt tttagaccct tgtacaaaga ttcctacata
    44401 acaaaatgag gtggagaaaa tgaaagattt aaggtataga agtgtctttg atattattgg
    44461 acctgtgatg attggtccaa gtagctctca cactgccgga gctgctagaa tcgggaaaat
    44521 catacgtagt atatttggcg aacagcctga ttctgtagat atttatctat atgaatcatt
    44581 tgcaaaaacc tatcgggggc acggaacaga tattgcatta gttggcggcc tgttagggat
    44641 ggaacccgat gatgaacgtt tagctgattc tttgaaattg gcatatgaag ccggtatgga
    44701 agtcttgttt gttcctaaga gtgaaaaagc cgaacatcca aactctgtaa agatgcttct
    44761 aaaaaaagga acacgaaagc tttcagtcac tggcatttcg atcggcggtg gcaatatcca
    44821 gatttctgaa ttgaatggat tcaaaatttc tttaagcatg ggtactccta ccttgatcgt
    44881 tgtccaccaa gatgttccag gtatgattgc taaagtgact agtatacttt ctgagaccaa
    44941 tacgaatatc ggcactatga cagtgacacg ggaatcaaaa ggtgaaaatg ccattatgat
    45001 aattgaagta gatgatcctc aagtagaaga aacggtaaaa agactcaaac agctgccaaa
    45061 tatcgacagc gtaaattatt tcgattaagg agctaaaaaa atgtttttat cgattgaaga
    45121 attagtagat caagcaaaag cttatccaag tgtagcagaa ttgatgattg cagttgaaat
    45181 ggaaatgagt ggccgttccc gtagtcacat catcgagatc atggaaaaaa acctctcagt
    45241 aatggaacaa tcaatcaacg agggaaaaga aggtgttacc tccgtcacag gaattaccgg
    45301 tggtgatgca aaaaaattag atgattattt aaatgaggca gactttttaa gtggagaaac
    45361 aatcttaaaa gctgtacgca atgctgtagc tgttaatgaa gtcaatgcaa aaatggggtt
    45421 gatttgtgct acaccgactg ccggaagcgc gggtgttgtt cctggtgtgc tgatggctgt
    45481 ccgagatcgg cttgatttga cacatgaaca gcaattggaa ttcttattta ccgctggcgc
    45541 tttcgggtta gtcatcgcaa acaacgcttc tatcagtggt gcagaagggg gatgtcaagc
    45601 agaagttggt tctgcaagtg caatggcagc agcagctttg gtttgtgcaa aaaatgggac
    45661 tcctcatcaa gcagcacaag cagtagccat tacattgaaa aatatgatgg gactgatttg
    45721 cgatcccgtt gcaggcttag ttgaagtccc gtgtgtcaaa cgtaatgctt taggctcttc
    45781 tcaagctttt atctctgctg atatggcatt agcgggtatc gaaagtgtca ttccgccgga
    45841 tgaagtcgtt gctgcaatgt accaagtcgg acgtcaaatg ccgtcgattt tcaaagaaac
    45901 agcagaaggt ggcttagctg ttacgccaac tgctaaacga cttgcggaag agattttaaa
    45961 taagagggcg tgataaagct ccttaatttc gagtattaag agattagtta tcttcataac
    46021 aaaaaacgaa gagaggacta attgcccttc tcttcgtttt ttattaatcc atcaatttcg
    46081 tattttttac ttcatcgatc gtttttgttc ctgcaagttg catcgtgatc gacaattctt
    46141 tgttcaggtg ttcaaaaaca gatgttactc cttctgcccc acctagattc aacccataaa
    46201 tcactggtcg gccaatcgca actaagtcag caccacttgc cagagctttg aagacatgct
    46261 ctcctcgacg gacaccagag tcgaaaatca ctggtacacg tttgttgact acttcggcaa
    46321 tttttggcaa tacttcaaag gacgcaggac ctccatctag ttgacgtcca ccatgattgg
    46381 atacccagat accatctgcc cctgcagaga tagcgattac tgcatcttct ggcgattgta
    46441 ttccttttac gataactgga agatgggtga tttctttgat tgttttgatg tcatctggtg
    46501 tcaagccttg ttttgcagct gcataaattt ctgcgattcc ttttccttcg ccattaccac
    46561 ttgcactttg ttcgctatac gcagctaagt taggcattgg taatggaaat tggaattgat
    46621 tgatgacgtc ttcttcacgg taaccaccga gcgttgaatc tgccgttaaa atgatagctt
    46681 tagcccctgc ttctactgct ttgttcaaaa tgaactcatt gaatctgtcg tctttactca
    46741 tatataattg gaaaaactgc ggtgcgcctg gcgctgcatc ggctgcgtct ttgattgtcg
    46801 tatttgcata agtgctgatg gaaaagattg atccagcagc agctactcct ttagctgtat
    46861 cagcttcccc tttttcatgt gccaatcctt gggccgctga tggcgcttgg ataatcggtg
    46921 tatctaattc aattccgaaa acagatgtat gcaaatcggc tgagtcgatt ccgcgtaata
    46981 tccgtggcat gattttcttt gtattaaaag aagtcgtatt ttctttcatc gtccactcat
    47041 cttcagaacc accgcgaata tagccaaaag ctcctgcttc catgcgctct tttacacgac
    47101 cttctagtta ggcaatgttt acaatatcga ttggatgttc ttcattactt gtatgataag
    47161 tcatagtaga tccttctttc atcttcttga ttacatataa atcatactaa acttacaaaa
    47221 agtaagcaaa catttactct cagatacttt tatcgctatt ctttccaaat aaatcgactt
    47281 acaagctgat ctacttcttg gttttcatga agcatactat gagaggcatt ttcacctgtc
    47341 actacttttt cctctatttc atttccgcgt tgcttcaaca acgcatagac cgctaatgca
    47401 ctgtttaacg gtactgttcc atcactcaag tctgtttcat ctagttgacc agcaatcaag
    47461 aaaaatcgag tggttatagg aatattaccg atcatttgct ggtaatcttg atagcggtta
    47521 gaaacgacag caggcccctt tgctaactca tctgtcagag actgcgcact atcatcgaca
    47581 aaatcattaa aaggcgcgcc aattgctgtt aatgtctgaa cttgtggcaa tgacgtatcc
    47641 tgtccatacg ttcctaaata gcgtagtgca ctaactcctc ccatggaatg ccccactatg
    47701 ttgactttat ctatgccgta gttttctttc agatacaaaa gacaagtttt gatccattct
    47761 gcttgattcc actcgttatt tttattatct tcaaacaata cttggaccat cggattgtct
    47821 gcttttccag acaaatctcc tgttgcttgt atttgtccat ctgttcctac tgttaaaacc
    47881 aattctttta ctgcttgctg atttttttcc aaacgccgca acatcccttt aaaggaattt
    47941 tctgtcccgc tgtagccgtg gaaaaaaagt gttggaatag tggttttttc tatcacttta
    48001 ctggattctg ccgttttttc tttatcagaa acttcagtag tatttatctt cgtcgtctgg
    48061 caaccactta acgcaaacaa actgataagg actaaagctg ctgcagttgc acgtttgcat
    48121 aaatttttga ttggttctgt catacacctc ttcctttcca tatagaaaaa agaaagactt
    48181 gaaaggccaa tcatatgatc gacatttcaa gtctctttat taatcgattt tatctacttg
    48241 atcgaaatca agttctgtac tggtttcacg tccaaacata tcgatgttga ctttcaattt
    48301 ttctttttct ccgtcaactt ctgttacttg tccttctaat ccagcaaatg cgccttcgat
    48361 gattttcacg acttcgccaa cttctacttc tagatcattt tgtcgcaggc tcataccgat
    48421 agaacgcaag atatgattga cttcttctgg aagtaatggt gctggtttgc ttccggctcc
    48481 gtgtgaacca acgaatcctg tcacaccagg tgtgttgcgg acaacatacc atgaagcgtc
    48541 tgtcatgatc atttcaacaa gtacgtatcc tgggaatgtt ttatgaacga tttctttttc
    48601 tttcccattt ttgacttcag tttctttttc ttcaggaaca acgacacgga aaataaagtc
    48661 ggccattttc atactttgcg cacgagattc gatatttgct tttactttgt tttcatatcc
    48721 tgaatatgta tgcaagacat accagttttt ttcaaaagat tccattgaag gctcctcatt
    48781 tcattgtaaa ataaaaaaac ctcagtacac ccgaagtttt tctttcgctt cattatagca
    48841 ctaaaagtac gttgtggcta gcgagttatt ttaaaatcca gccaaataag ctttggatgg
    48901 ctgtatccat tacgtaaaac atcaatccga aaataataga agtttcgatg actactaacg
    48961 tatctttacg gagttgtttt ctgcttggcc aagttacttg tttgatttca tcttttacgc
    49021 tttttagaaa tttcatgaga caacctccct tgctactgtt tatttcgttt ctttatgtaa
    49081 tgtatattga ttacaatatt tacaaaactt attgatttcc aaacgttcgc cgctttttcc
    49141 ttcactgact gattttgtgt agttgcgaga cccacaaacg gaacaagcga gtgctgcttt
    49201 tttctttgcc atttacttct gcccccttgc tgagaatcag acttatactt cataacagta
    49261 tcacgtaact ttttacttgt caatttgtga aataaactat ctattgtttt ggataaaatt
    49321 atgatatgat taatttgaaa ttaagctaaa atgagacaat tggaggtata gcgatgctat
    49381 taaaaacact tgtatataag aaaaaagatc tgacaaccgt tacagagact agtacattag
    49441 aagaagcatt aaaaatttta gaaacttccg gataccgttg tgtgccgatc ttagattctt
    49501 caggtaatat tttccgtgga aacatttaca aaatgcatat ctatcgtcat aaagcaaatg
    49561 gcggtgatat gacgcttcct gtcactcatc ttttgaaaaa cgctacaaag ttcatttacc
    49621 tggatacttc tttcttcaaa gtattcttta cgatcaaaga gcttccttat attgctgtcc
    49681 ttgacagtga aaatcatttt tatggtattt tgacacatag tacgttgctt aatatgctct
    49741 ctcaatcttg gagcgtagaa caaggaagct atgtactgac aattgcttcc acaggaaagc
    49801 aaggagattt ggctgctatt gcaaaaatca tttcaaaaca cagcagcatt gccagctgta
    49861 ttactcttga tatcgaaaaa gacgaataca ttcgacgtac attgatcacg ctaccggcta
    49921 acactgaagc gaaagtatgt gaaacgatcg tcaaccactt agagaaaaag aattataaag
    49981 tggtagaaat tgaaaatttg caaaaccaag aagcataatc aaaaagcgaa aaaagaaaac
    50041 agctaatctg ctttcttttt tcgcttttta taattagaca cgcttttcaa aatcaagcgc
    50101 gcgatctaaa taatacatca atggtgctga aacagccatg acgataaact cacttaatgc
    50161 aagcgtgcca taggttgtcc aaaatgcttg gccacctgtt ggaactaaca tataagcaat
    50221 cagtcccatg ctgatggtaa agaagatcgt gttcaatact aaacgcatct ttacattttt
    50281 cactttgttt tgcaataaag ctgtcaggcc taaagaaagc aatgtttggc cgccaccaaa
    50341 aaccacatcc atgataccaa aaccaaagaa ggcattatag acgatgaccc cgcctaaaac
    50401 tccccaaagc aatttacggt taaagacaac taaatgattc aaactttctg aaatacgaaa
    50461 ctggatcggc cctgaggata caggcgcaac taaaatagtt aacgctagat aaagagccat
    50521 gatgatgcca tttacaacga ttacggataa ccgttgtctg cttttcgttt tttgcatttt
    50581 ctctcctctt ttctcctagt ttttttaacg cgggatggtt gatgaaccgc ggttatgtga
    50641 aacaaacaat aattataaca gacttttcat ttatttcaat ccgtcttatc tgcttttaaa
    50701 aaagcaaaag cttaaacaat gtaaacgttt gctaaaaatc gtgggatatg gtataaagta
    50761 agtgtaaggg gtcataagaa ttcccagtaa agcagacgaa gtaggatctg caagaacaga
    50821 attgttgtga aacttaaata aataaaaaag gatgtgggaa tttgagcaac ctcttactag
    50881 agaacggtct agcaagcagc tgaagatcta agtggacatg ccgaaccttg gaacttctcc
    50941 ttacgtaagt aatggatcat gcgcttgcta ggcttttttg tgtttttcgg tcttcggacc
    51001 tttttcattt tcctagactt ctgctataat aaccaagaat taattttgta acagattttt
    51061 ttgaaaaaac aagtttcttt cattcaaaaa atagaaaaag cttgctaatt attggttaac
    51121 cagcaaacag gagtattaaa atatcttgtt ttattgaata gcaggaggaa atcatgaaat
    51181 tccattatca tatattgatc aatccatcgg caggcagcgg aaatggctat aaagtagcag
    51241 aaagaatttt accggtatta aaaaataagc atattgacta tacacttcat tatagtgaat
    51301 acaaaggaca cgatgctgag attgctgaaa ctttggcaaa agaaacattg attccttgga
    51361 tagaagaaga acagaaaaca atcgatactt tccccctttt gatcatcgta ggaggtgacg
    51421 gcaccttaca tcaggtactt gatactttct atcagatgga agtagaattc ccagttgctt
    51481 atattccagc aggttctgga gatgattttg ctcgaggggc aggccttcca aaaaatccca
    51541 aaaaaggact tcagctgatt ttagcagctc aatcaccaga aaaagtccac ataatggctt
    51601 atgaagaaaa aataagtgaa aaaaaaggaa tagctgttaa taatttcggt ataggattag
    51661 atgcagctat cgtccatgcg acaaatcatt cttccacaaa aaagcgattg aacaaataca
    51721 acttaggatc attttcgtat ttattctcta ttctccgtgc tttattcact caaaaaggat
    51781 ttccaattct ggtagatgca ggaggaaaac aattaagttt ttcaaacgca tttttatgta
    51841 cagcaacgaa gcatcctttt tttggcggag gaatcgcgat tgttccaact gctgatgcgt
    51901 ctaaaccagt cattgatttt gtcgtggtcg aacgaatcaa tttctttaaa atcttgtggc
    51961 tcattctttt acttatacag aaaaaacaat tgaaatcgaa atatttccat cactacacaa
    52021 caaacagatt acgtatcgtt tcaacaacac cgcaacatgg tcaagaagat ggagaagaaa
    52081 tggaaaaacg accttttgat atcacaataa ccacaactaa acagttgttt tggtgttaat
    52141 aaaagaggtt ttgtcagaag ctacatctgg aacaccgttt attcggaaaa aaggactgtg
    52201 acacgacttt tgtcacagtc ctttttttac tatgcagtta attctttgcc caattgggtt
    52261 gccatcgata gtttctttct ttacccaaaa taaattggat cattgaaaac accgcagcaa
    52321 aagcaactaa gacacaacca ttgaaccaaa aagattctgc aaatgtttga ttgtaactga
    52381 gtgtttcact gatcaagtta ttattttgaa caaaccaata tgttggtgtg aatgccgcta
    52441 ttttgctaac catttctggc aagtattctg ctggtacaaa caccccaccg ataaagcaac
    52501 tgcctgtgat aaaaatatct ttgatcccac cgctggtttc tgagtttttt accaatgaag
    52561 tgatacaagc cgaaaagcta atgatcggca ataaaaacaa gaaagtattt aaaatatgat
    52621 accataccgt tatatcccac gaggtgtgga tcactaacag aaccattaga agtaagaagc
    52681 cactgaacaa cagcagcgag taactaatca aactaaaggt tactttgcga ttcaagtttc
    52741 gtttggtaat gggcgcactc tggtttcgtt tactgatctc tttgcgatta aatgctagat
    52801 tgatgacgct gaaaccgcta aaaatggata gaaacaaccc ataagacaag aaattaaagg
    52861 ttgtgcccgt caacagcttt ttcatccgct gactatatcc cgcacttagc tcaacttctc
    52921 cagtaaccga gagtgccatt tgtgtctgtt ccatagctgc atcgattgtt ttatcttctt
    52981 cttgaaacag aatcagtgtt tgcaaaaagg tgttcacttg ctgtgtaaca actgttttag
    53041 aaaaggcatc tgggcgactc tgtatcttga tcgtcggcat ctttcctact tcgacttgtt
    53101 cggtaaagtc tgcaggcaga tgtaagataa tgtttacacg attaaaataa agagcatcat
    53161 cgatttcttt ttgtgaggtt ccatccaatg taacgactgt ttccttgtca ttcaaatatt
    53221 tacgaaggcc atcgactaca ggcgactctt cttcactaat caaggcgatt ttcgcatctt
    53281 gcagagaggt attttcaaca tcaatatttt gcgcaaaaaa gaatgtggca acaacagtga
    53341 taattacacc tatcagtaaa ttcgatttat ttgctttaag caatgtccaa atcgttttat
    53401 aaagcgtcat aacgcacccc tctttccatc caagcatttc ctaacgcaaa aaggaaaata
    53461 aatccgatca accatagaag attggtataa aaactagcca aatcagtgta gaaataaagt
    53521 ttatacaaac tttcgctgat caagttgacg agatttaatt gaccaacaat cggaatatga
    53581 agatcaatcc aatacttcac ttgttccgac cccatcatac cagcaaaaaa gctcatcgca
    53641 atcgtcactg aaatcaagat gctatccttt tgcaccagat tcatttttgg tatcaaatta
    53701 ccaaccaatg tacctaacaa aatcgcacac aacgacccca gagcggtaac aatcatcaac
    53761 cattgccaac gttcaccaaa gtctacttga tagataaaac gaaagacagc taacataata
    53821 taaatctctg tcaaaacaat cgtaaagctt gctgccaaat tagcgattga aactaacgat
    53881 tgctttctag gaatcaagga caagcgaata ccatttgacg attgatttgc ttgctgatcc
    53941 tgtacattgc ggacccccca catcgtcccg tagagaatcg ccattccaat cagagtgaag
    54001 aaataaaaac ttttgaaact catattacga cctgcatgaa cttcttgaaa agatacttct
    54061 tgttcaaaaa cagtcatgat gggcgcgaga tcaacgttct ccacttctgc cactttactc
    54121 gaaattatac caatacgctg taaaaattga tccatgacgt ttttcatcaa cgtctgactc
    54181 attcctgctt gacccacatg gagcgaaaca gatgaaccat caatgagata aaaaccagcc
    54241 aaatcatctg catttagctt ttcattcgct tctacttccg atagttcctg tacttcaaat
    54301 aatggtttat cattgacttc gacttgttct aagactgtgg taaaattttc cgaaagcgct
    54361 gtttgatccg ctttgattac aattccagta ttaatcgttt cgagattgcc accttgatca
    54421 atctcgccaa aggccgccat aaacatcaat cctaaaagaa ttggaaaggc caatgtccaa
    54481 aacaacatgg atttatttcg cagcagtatt tttgtgcgat atttataaaa atgccaaaac
    54541 attatttccc ctcctctagt ctctcaaatc cttgccagta atctctaaaa agacatcatt
    54601 caaggacgct tctttggttg ctatttttcc gtaactgatc ttttcttctt gtaagattgt
    54661 aagaatcggc aacaatactg tatttagttc agtagttgtt acttggagct gacctttttt
    54721 ataagcgatt ccatcagaag ctattgttcg ctgacaacac gttttctggg agtaatggga
    54781 tgtcgatcgt caaacgatcc gccgtccgta ccatatcttt tagagattct ttggttcctt
    54841 tagcaatcac ctgtccttga tccatgatca cgatctggtc gcaaagaatt tctacttctt
    54901 ccatgtaatg tgttgtatag acaatggttg ctccttgtcg attcagctcc ttgatacttt
    54961 ctaaaatttt attccgactt tgggggtcta cagctactgt cggctcatct aaaaaaatta
    55021 accgcggctt gtgggcaatc ccacatgcga tgttcaaccg acgtttcaag ccaccactaa
    55081 gttctcctgg acgaaacgaa acatattttt ctaatcccac taattgaatc acctcttcaa
    55141 tcaaggcttt ccttttctct ttttcggaaa catataaacc gcaaaaataa tcgatatttt
    55201 cttgcacact tagttcgtca aagaccgcaa cgtcttgagg aacgacccca atcattgcct
    55261 tgacagcata attttcagga gtcattgttg tcccgaacaa tttaatggtt cctttgtcat
    55321 aatttaacaa agaaagcata cagttgatgg cagtcgattt cccactgccg tttggtccta
    55381 acagacctaa gacttctcct tcttgtactt gcagatcaaa atgattcaat gctacaaaat
    55441 ctccatagcg tttgactaat ttatcaattt cgataatcat catgaaaaac tccttccaaa
    55501 tttcttgttg atctgactat aataaagtgc aagaaaagaa actagtgacg attggctaaa
    55561 ccacacatga catttgtcac aatgaaggag tctgctatgc ataaatctcg gctactcaac
    55621 gaaactagct ttctactggt tatctcattg cttttgctgg taagtcaagg attcgttgct
    55681 atgcaagtta tctatttatt gatcgccgtt ttattcactg gtgtcagtta tttactgcct
    55741 acaaagccaa attggatttt ccaagttatt ctatttcttt tatgtgcctt tttacctgat
    55801 cttgtcctgt ttctgccagc gacgatgcga gtgatcgccc ctgaagaaag ccaccttgat
    55861 tacttgtttt tgttaggttt tttgttgatt tcgacggttg gtaatcatcc ccccatcaag
    55921 gtcgcctttg tcgtaatttt gctgtttttt tccttttact tacgaaaaaa agatcaacga
    55981 acgaccgatc ttgagaaaaa gtacattgtc tccaaagata ctcattggga aaaacaacaa
    56041 gagttatcgg aacaaaataa agcattggcc ctgtcacaag aaacacaatt agccttgcaa
    56101 attgtggaag aacggaaccg aattgcccga gacatccatg acaatgtcgg tcatctgctg
    56161 tcaagtgcga ttttacaaat tggtgcgctt gaaatgatca atcaagaacc aaaactaaaa
    56221 gaaccattag aaaatttaag tgccaccgtt cacactggga tggatcggat tcgtcaaagt
    56281 gtccatgacc tccatgagac atcgatctct tttcaacact ccttagagtt tctgatcgct
    56341 gattttcctt cttctgttac gattgaagga aacttgtttg aaggattgaa tgaaacgcag
    56401 caaaactgct tcttaatggt catcaaagaa gccttaacca acagtatcaa acatagtcat
    56461 gccaaaaccg ttgttttaca ttttcgaacg ttgccggcct tttatcgctt gcaaatcacg
    56521 aatgatggca ccagcccaca aaaaaattct gctcccggta ttggtttgaa aacgatgcgt
    56581 caacgtgttc aagaacaaaa gggacaagtc catattttcc aagaaaacca gcaatttcag
    56641 ttaacgatca ttttaccaag ggagggacac caatgataac agtagtcatt attgagatga
    56701 tccatttgtg acgaaatcgt tacaaaccat tttagaaagc acgaaagaga tccgtgtgtt
    56761 aggcattggt cattgtgcca aggatgcgct agtcttatac gaaacccatc gtcccgatgt
    56821 tttgctgacg gacatccgca tgcctaaaca aacgggcatc gatgctgcca aagaaatttt
    56881 ggctaaattt cccaaagcca tccttttgct tttgacgaca ttcaaagatg aagaatacat
    56941 ccgcgaagca ttttccatcg gtgtcaaagg gtatttaatc aaacagaact tgcaagcgat
    57001 tattccttct gtcaaatccg cttataatgg acaggccgta tttggtaatg aaatcatcga
    57061 gactttcact caaatgatga agaataaacc gacgattgat agtcatgctt atgcttcttt
    57121 tagtgaacgt gagcttgcaa tcatcaaaga agtagctgcc gggaaaaaca ataaagaaat
    57181 tgcagatgcc ttgtacttga gtgacggcac tgttcgcaat tacatcagcc aattactaga
    57241 aaagctagat ttacgggatc gcacgcaatt ggctatctat ttttatcagc atttgcaata
    57301 agtcttatct aacacaaaaa aacctgaatg atgctccttc gcatcattca ggtttttttc
    57361 acatcttcta ttcaattgtc ccgcaaacca tttcctcacg attgaaagaa tcaaggattc
    57421 gcagggctgc caggattcgt tggattgttc ggcgtgttag gcggaaaaat aggcgccttg
    57481 tctaacgttt tttctagttt tgattcttca cgatcgtctc gttctacatc aggactttca
    57541 ttcaatttga attctttttc catctcatct aactttttaa agtcattgcc agattctttt
    57601 gctaatttcg ctaatttatc ttcggtttct ttagccataa agtaacgccc cccttttgat
    57661 ttcagcttag catatcacac tgaaaaaaca aaagaaaacg ctaaccaacg atcattttta
    57721 gctatttctc atctttaaaa tcaagcattt tttgccggta taaaatcgta gggagaactg
    57781 ttttccatac caatcatcgg atctactaac tggttatcga tcacttctgc tgtaagaacg
    57841 aaatctttag aaacagcagg ttctacctct tctttctttt cttctccaac aaatgaagaa
    57901 aacagatctg gttccactgt ttccattact tggtttttcg tttcattcgt cccactgtca
    57961 tcttctacag gtagcttttc ttttacaacc cgtggctctt ttgtatagtt cccatcttca
    58021 aatggatcat ttccgaccaa agaatcttca taagctgcta gtttggtccg gagagtgata
    58081 ttcattttat cattatccat gatccttgat ttcaacgtag tcatccggct tgctgattca
    58141 ttcgctacac aagtgacata ggcttgctct tcccctaaca aaatcaacag ttccttactg
    58201 cgagtcactg ccgtgtagag caaattacgc tgaagcatcc gctgatattg atggaccatg
    58261 ggcaaaataa ccatcttgaa ttcactgcct tgtgatttat ggattgagca acaataagaa
    58321 agagtgattt tattccattc gtttctttta taagtgacct catttgcatc aaactggata
    58381 actaattcat ccactttatc ttcagaatct tttgccaaga tgatacccgt gatttctccc
    58441 atatctccat tgaatacatt caattcggga gtattgacta attggaggac tttgtctcct
    58501 atccgataaa cggtgtcgtt ccaatgtact tccttttttc caggtttccc tggattgaat
    58561 atctcctgca tcattttatt taacgcatcg atccctgcag gtccccgata cattggtgct
    58621 aatacttgga tatcttgtgc acggaatccc ttatttttcg ctttttccac aattttagag
    58681 atcaagggtt caatttgata agcatcactt cggaaatagg aacgatcttt ttgattcttt
    58741 gtgaaatctt ttggcagacg tccttctttg atctcatggg caagaggaat aatactagaa
    58801 ccatcacctt gccgataaat ctgattgagt tccattttgg gaatttgttc gatttccaaa
    58861 agatcatgga gtacttgacc aggaccgaca gagggaagct gatctttgtc tcctactaag
    58921 ataacttgca tattcgtcgg aatcgctttg aataatgtgt tagccagcca tgtatcgacc
    58981 atagacatct catcaacaat caaaagtccg ccttctaatt ctttcgtact gactgaaggt
    59041 gttttttccc gtccattcag ccccagaaga cgatggatcg tactggcagg cagacctgtc
    59101 gtttcgttca ttcgtttagc tgctcggcca gttggtgctg caagtagaat aggaaaaatt
    59161 tcttgggtat attttgaagg atccaattcc agtccgttca actctgcaaa aagattgacg
    59221 attccgttga tcacagtagt tttccccgta cctggtcctc ctgttaaaat aaatagaggg
    59281 gaacggattg cttcagcgat agcttgttct tgcgaaggtc catactgtat gccgaatatt
    59341 ttttcgatac gccgaatatt cttctgcact tctttttcag gataatggat ttctttttta
    59401 cgactgagaa ggcgctggat cgaattaccg atcccccatt cagaaaagta caaactgttt
    59461 tcgtaaagat tagtctcttc ttgttgtatc tttccttctt caacaagttg gataattaca
    59521 gtagcaacct gatcaggctg gatttcaatt gggcgacttg tttctaaaat acggatcgtt
    59581 tgctgaagca atgtctccgc cggtacgtat gtatctcctg tttgaactgc atgctgaaaa
    59641 atctgatgca agatagctgc tcgaattctt ctcggtgaat ctgctgcaat accgatttgt
    59701 tcggctagat tatctgcacg tttgaacccg attccttcta tgtcttcgac tagctggtac
    59761 ggattttctt cgatgatatc caaagactcg ttcttatagg cctggtagat actgaaagct
    59821 aactgactac cgaacccgta acgattcagt cccatgatca cttgatccat cccgtggttt
    59881 agccgaatcg tctcagcaag catttctctt tttggcttcg tcaaaccgga gatttgtttt
    59941 aataccgaag gatcagcaat gattttttcg atagcatctt ctcccagcaa ttctacaatt
    60001 ttttctgctg ttttcttccc gattcctggg aatttttcgc tggaaagata cgctacgatc
    60061 ccatttgcag ttgttggctt ttcttgctca tatctttcga gtttaagctg ccttccgtat
    60121 ttaggatgat ccactaattc tccataaaaa cgataagtct cattttcttg aatatcgccg
    60181 aaacttccgg tgactacaat ctctttttca cggtaatcag ctgtggtttc actgatgtgt
    60241 accaaaagca ctttgtaaaa attactagga ttttgaaaaa aaatcgcggc aactgtacca
    60301 acgaaataag gcatttcttc tggctgcatc ggaagccgcc tccttcttct atagtaaagg
    60361 ttctggtgct gtttcagttc ctaaaaaatc tgtttggttc catactttca gttcatatgg
    60421 caataatctg caaggctctt cagtctctaa aatcgtcaaa ctactattga acaatccacc
    60481 catttcacgc aactcactta gctcttttcc tgtcatccat tgaatggctg cagttaaaga
    60541 agctccatgt cctacgaata aaagtgggcc atctttatgt tgggcaaccg catctgctac
    60601 aacagtttcg atacgtgtga ttgccgattc aatcgtttct ccgtgaaaag gagaaggatc
    60661 atacagatct aaatgattac gcaaattcgg cagattatcc ggatatttct ggtacatttc
    60721 atcgatcgac tgaccttcta aagtacccag ccctagttct cttagcttat ctgtataaaa
    60781 aatctctacc ggacgagcaa gctctttgtt gataccttct gctgtatcac gtgctcgctt
    60841 tgctgtactg gaataaattg ctttaaaagg aacatatttt acctttttcc caaatgcttt
    60901 gatttcttcg taactttgtg gcaaaagcgg agaatcgcca ttgctccctt gaaaacgtct
    60961 ttcctgattc cattgtgtct tcccatgtcg ggtaaaatat agttccatac gcagcaaact
    61021 cctgtctttc ttttatttta ctctataata aactgtctaa tccagcttgt cattttcata
    61081 gtgatgcgtc aattctaaat tagggaatcc ttgctggcga agtgcttcat acactatcat
    61141 tgcagctgta ttcgataaat tcaatgagcg gacatgctca tcattcatag ggatgcgtaa
    61201 acacttttct tcgttttcac gcataaatgt ttctggcaaa ccggttgttt cttttccaaa
    61261 taaaaagaag tgctcttctc catcagcaaa attttcgtca ctatatactt tatgggcaaa
    61321 ttttgagatc aaatgtagtt tacgattacc taaaaatgtt aaaaaagctt ctaaattact
    61381 gtggtaagta atatttacat cattccaata atccaaccct gcccgtttta gatgtttgtc
    61441 atcagttgaa aaacctagtg gctcgattaa atgaagcgga gtattcgtgg ctgcacacgt
    61501 acgggcaata tttccagtgt ttgcagggat taatggttca aataaaacga tatgattcat
    61561 caggatcatt cctctcatat ttatgttcgt ttctattttc tgacaatttg atttttgcat
    61621 aaaaaaaaac gtatcaactc ggtgtcagtc actgcgagtc gttacgttag tgaagctctt
    61681 ctcactaact tttatcagaa caggaacctg ataaaaacca atgaaaaaac aacttgttgc
    61741 taatataaca ccctcaactt ttttttgcaa cctctactca ttaaaaactg ctagaaaaac
    61801 gttttctctt agttcctttt aataattcta tgtcaattgt aatcttcttc aaaggattct
    61861 tatataagtc tgctttgatt cgctcttcta cctgccattc taaaggtgac atggccaaaa
    61921 gatctttttg attttcctct ggtatctcaa attcataggt tacacgctga cgttcagtta
    61981 atttcattgc ttcagcaaac ttggctacta cacgttcatt ggaataactc tgtttttcag
    62041 gttgattcgg ataaaaagcc tgacgtagtt cctttaaata attttcttgt ggcaccacct
    62101 tcaacacttc tccatcttct gagagtacac gttggaattc ttggtaatga gaaggcgaaa
    62161 agatatttaa aaccgcgttg aatgtttgat cagcaaacgg caaattggtc aaatcagcta
    62221 cacaccaaaa tgcttcggca gattgttctg tagctgcgta gactccttct tttgaaatat
    62281 caaatccaac agcattttga atctttttca attttgaaag ttcattcaag aagctacctt
    62341 ctccgcagcc aacatctaat agcgagactt cttcaggtaa atgctgcgca atagtctcaa
    62401 taacgggctg atacatgcca gattggatca ttctacgcct tggaacgaac attccttgat
    62461 cgtattctgt tttaaccgca tgggataaaa aataaagtgt tccttttttg gaaaggtcaa
    62521 aacggtgatt atttttgcat atcaagccat tatcagactt ttttacttct tcttggcaaa
    62581 ccggacagcg gaacagctga tgattttctg ccaaaaactg gcgtcctcgg tcaatttttt
    62641 ttaacatagt tccccctcat ttctgtttta tcttaccgtt agatgctcac tttggcaact
    62701 gctaaaaata tgatacaatg cctagaagaa agtgaaagat aaaggagaag attagatgat
    62761 caaagaattt tgcgctgaaa actacacatc tattcctcta gcaattgcta gaggagccga
    62821 tcggatcgaa ttgtgtgaca acttagcggt cggtggcaca accccgagta ctggtgtgat
    62881 cgaagaaacg ttaagttatg ctggggaaaa agatatcccc gtaatgacga ttattcgtcc
    62941 tagagggggc gacttcgtct ataacgatat cgaattgaaa atcatgcata ctgatttgat
    63001 tgaagcaaag aaattaggga cggatggcgt agtatttggt tgtcttactc cttcaggctg
    63061 gctagacgaa gaggccttag aactattgat cgaaacagca gaagggttgc agatcacctt
    63121 ccatatggct tttgacagta ttcctgaaga tcggcaattc gaagcaatcg attggctggt
    63181 agaacatggt gttgaccgta tcttgactca tggcggtcct gctgacaaaa ctattgtaga
    63241 aaatttccca cggcttaaag aattgattgc ctatacagat ggccgcttaa tcattttgcc
    63301 tggtggtggt gtcactgcag agaatgcagc acatgtagct aaagaattga acgtaagcga
    63361 agtacacgga accaaaatcg tggatcttca gttataatct tataaacaaa aaaacatttg
    63421 caacaggcat aatgcttatt gcaaatgttt ttgttttttt acataaaata gcccataaat
    63481 aaagaagcaa tattgaaata aatcagtaca ctcgtcaaat cgctcaaagt cgtgataaag
    63541 ggaccgcttg ctactgctgg atcaaatcct agacgatcca ttagcatcgg gattaaacta
    63601 cctgcaagat tcgccactgt gattgcaaat agcatagcca tccctatgac aaaccccaag
    63661 ataaaattat gtttccaaaa acctacgatt agaaaaatcg tgatccccgt aacagctcct
    63721 gtgacaacgc cggtcaagac ttcagccaaa acaagtcgaa caaatccatg atctttctca
    63781 tcagaaatcg caagtcgacg aacagccaca gctagcgact gggttccagc attaccggca
    63841 gttcctgtaa tcagcgaaat gaagactgct aaaatactcg cttcacttac caagtcttca
    63901 tagtgactga ttaaagaagc ggtcgacata cctaaaaaca acagagtgat cagccaaggc
    63961 aaacgtcgag acgctgcctt tactggattt tcattaattt cttccacatt gaccccggca
    64021 agtcctgaat aatcgctagc agcttcatca tcaataacgt cgatgatatc atcgactgtg
    64081 acgattccta acaaatgatc atcataatcg gtaacaggaa gagctaagaa gtcataatct
    64141 ctaaatgttt gtgccacatc ttcttggtcg tcgcctacat gaactgaaag cactcgttcg
    64201 ctcatcagat cagaaatcat tgcgtcgtca tcattcacga ttaggtcgcg cagagaaata
    64261 acccctacta gctgaccttc ttgattaacg acatagatgt aatagattgt ttcagctaca
    64321 tctgcttcgt tcttcagcac gtacatcgca gagcgaacag tttgattggc tacgatcgaa
    64381 acaaattcag ttgtcatgat cgcgccagcc gtttcatcct cgtaatggag aagttccttg
    64441 atttcactgg catcgtctgc cgacatcaaa cttaaatatt tagcaatttg ctttttatcc
    64501 agcgtattaa gcaagtcaac agcattatct gtatacatct cagaaagcat atcagctgca
    64561 tagctaggac gcatttcatc taggtattct ttcatatgtt cgttgtcttc ttcaatcaca
    64621 tcgaacatat ccgctaattc tttaggcgac agataggaat agatcagctg cctgttctct
    64681 tctgtaagag attggtagaa ttgcccctgc tcatagatat gcatctctaa aaaactgttt
    64741 ctgaatgcct gaatattatt ttcccttaaa tcttgagtca actgggcaaa tctttcctct
    64801 aattcttgat tttcatccaa accaatctca cctcgcctta ttcttcaaac cgtctcacaa
    64861 ctgcctccat gtctgcggct aaaggctgct tgaactccag caactcttct gtaaatggat
    64921 ggtaaaaacg cagatcataa caatgaaggg cttgtctttt tattcccaga tccattcgcc
    64981 cgccatacat atcatcaccg agcagggcac agccaattgc ggaaaaatga actcttattt
    65041 gatgtgtcct tcctgtatgc agctggatat caactaacgc gatttctgtt agtcgcttct
    65101 ctatccagta ctcagtctgt gccgaacgtc cttcatcaga gaccattcgc ttcaatagcg
    65161 aagaataatc tcgggcgatc ggcaaatcga tatgtccatg tgccgataaa tctgaaagcc
    65221 ttccactgac taaggcctga tattttttca caaacttctt ttcacgaagt tgcatatcta
    65281 attttgcgtg cgcaaatcca tgctttgcaa aaagcatcaa accagatgta tcccgatcta
    65341 gtcgcgtcac cacatggatt acttggtttt cgtaaccttg ttttttataa taagccttta
    65401 cacgattagc cattgtccca tttggatggt attgggcagg aatagacgaa acgcctgctg
    65461 gtttatttac taccagaacg tgttcatctt catacacgat atcgatcggt gtttcatcca
    65521 aaagtacggt ttcatgttct ccttcagcag gaatcacaat ggttacctta tcatccttag
    65581 ctagagaaaa caagacattt tctacttgat cattaacttt gatttgaccg ccttgaaatt
    65641 ttattttcgc taacagaccc tttgagatcc ctttttcttt taaaaaatat tttacttgct
    65701 gagaatgatc tttctcataa tcccatgtaa actgcatatc aatcctcact aataaaggca
    65761 tctttcacac gatgccaaaa atgcatatgt cgataagaag caaaatggat ccgttcttct
    65821 gctattcgat aataaattga gcggatattt gcttttgcga cattcaattg atcaaccgtt
    65881 acaagataat cttctgtatt ttccaatttt atttctagcc attcatcatg ggcaatcacg
    65941 atcggagaac ccaaagtacg aaacactcga ttattcagtg aagcaatctc tgccaactga
    66001 aaggcattga tactaggatg gatcacagca ccgccgacac ttttattata tgctgtcgaa
    66061 ccagtaggcg tagaaatcgt caatccatct cctctaaaac tttcaaacag ctcgtttttg
    66121 atgtatacat cggctaccat cgtacgattg gcccgtttaa tcgttgattc attcagtgct
    66181 aaaaaatgct ggtccggtgt ttcatccaaa taactgatcc gaacatccag caagggataa
    66241 ctaacacttt gttcccggtt cgttcgtaag ctgtctacta gttcttccag ctcgtaatcc
    66301 cgccaatccg tgtaaaaccc taaatgacct gtatgcacgc ccaagaaacg cacatcattc
    66361 agacaatgac tgtagtgatg gaacgccgac aataatgtgc cgtctccgcc gactgagatg
    66421 accaattctg gctcatgatc atctcgttga atccctgctt gttctaaaag tgcgttcaaa
    66481 cgttctgtca cttctatagt ctttgcttct ttattatgaa cgatcgctac tttcatcccc
    66541 tgcctcctct ctttcgcttt ctttcttcaa aagcgttcga tagtagacat catctgattt
    66601 tcctcttcca tgggagaata accgctgtgc ttcttggatt tcttcacgga tactggacat
    66661 ctcttcatcc aactgatagg cagcttctgc cgcacgctga agtcgttcac tcatttcttc
    66721 tggaaaaacg ccttgatatt tataattcag cgaatgctca atcgttgccc agaaattcat
    66781 cgcaagagtc cgaatctgga tttccgccaa aattttcttc tcaccgctga tcagctgtac
    66841 aggatactcg atcaccagat gataagaacg gtagccactt gcttttttat ttgtgatgta
    66901 atctcgttct tggagaactt tcatgtcttt tcttttacgg atgatctcaa caacttgatg
    66961 gatatcttct acaaactgac acatgatcct taacccggca atatcagaca tttcttcttc
    67021 taaacgtccc attggaatat gccgtaattg tgattttgtt acaatactat cgactggctt
    67081 gactctccca gtgacaaatt caatcgggac atgtcgattt tgttcacgga actgtttgcg
    67141 gatcccccgc agtttcactt tcaattctga tacagtttgt tcatatggtg ctaaaaatgc
    67201 ttcccaatct cgttccatag ctgatacctc tacttcatta acattcattg tttattctac
    67261 catatatgca aagttttttc gtactcttga tttatgcatt gaccaaaaaa agaaaattag
    67321 gcaaaataga caaaaaggag tcgatcaaat gacacaaatg cttgaaatcg aatataaatc
    67381 tatgctgaca aagcaagagt acgagatatt catcgctcac tatcaattaa cagataaaga
    67441 tttccgtgta cagactaata tttatttcga taccgttgat gaacagctga agaaacaaaa
    67501 ttgtggccta cggatccgtt tcgttggtca tcaagctgaa tatacattaa aaacacctgc
    67561 tgaaaaaggg cgtctcgaaa caacggatac ctttataaca gaagaagcag aagcatttat
    67621 cttcgaaaaa cgtctgcctc gttcaggcgc agtttttcaa aaactttctg atttgaatat
    67681 cgatcctgct tcattaatcc aaaccggaaa gcttacaaca aaacgggctg aattccctat
    67741 tgaagaagga cttttagcta ttgatgaaag ctggggagac aatctacacg attttgaact
    67801 ggaactagag gtaggggatg catctgtggg aaaaattgct tttataaatt ttttaaaacg
    67861 tttttcttta ccttatcgtc ctgctaagaa caagatccaa cgtatgcttg aagctaaaaa
    67921 ttagaaacct ttcattttca caaggcactt gagttcattt ttttactttt ttctgttaag
    67981 ttataggatg tgaaagaatc tagtcactag ttgtatagaa tctattttgg gggagattca
    68041 tatgatcgaa atctatttat ttgttaatcc tttaggggaa tactgtttcg aaatggaaca
    68101 acagttatta caatttatcg aagaagagta cgggacacca tcaaaagaaa agatgcaatt
    68161 tcgctttctt cctttggtca atttgcagac aattggggat gtcatgcaac aaaaaggaat
    68221 ttctcagaac aatcttgagg aacgtaatca cttattctca atgacttatt ctgcagcatt
    68281 ggactgcaaa gcggcgcagt ttcaaggaaa gaaaaaaggc cgccgttttt tgatcaaatt
    68341 gcaagaagca gtcggctgta atgacatacc atattctcaa gaacttgctg aatccatatt
    68401 tgaagaaatc ggcggcgatt tgaatatgtt taaagaagat cgtcagtctg acttcgttaa
    68461 agaagtattc ttttctgatc aaaaaattgc tcgggaaatg ggcatcacaa aacacccttc
    68521 tgcagtcgtt tacaattatg cctgcgaccg tgattttggt gttttagtag aagtaaaagg
    68581 tacaagtagc ctttggagaa tcacagagct gtgtaaaaca acagataact catatcaagt
    68641 ttttaatggt gaacatttac atacaaatga ttctcagttc cattcaagaa ctagccattt
    68701 acacttgctt tctaattaaa aaaatacgtc gactccctta caagagagcc gacgtatttt
    68761 tttcgtttct attcgagaaa atcaaaaata gaaagcctta taaacgatcg atcaattctt
    68821 ctaattcatt tagacgttgt tcaaacatcg acattgcatc ttcaatatat gcagcctgtg
    68881 tcatatcaac tcctgctttt ttcattactt ccacaggata atcgctgtta cctgctttta
    68941 ggtaagccaa gtagttctct agtgcctctg gttcctggtt tagtattttc ttcgccagtg
    69001 ctgaagcagc agaaaagcca gtcgagtatt ggaaaacata gtaattataa taaaaatgcg
    69061 gtatccgtga ccattcgaat ttaatttctg ggtcttcttc gactgctgga ccataatatt
    69121 ttgcattcaa tttaccataa ctatcactta ggtattcact agtcaatggc acaccttttt
    69181 catcttccgt atgcatgaaa tgctcgaatt cagcgaattg tgtctggcgg aaaactgttc
    69241 ctttaaaccc atccaagtaa tggttgagta cataagcccg tacacgaggg tctttttctg
    69301 tttccaataa atactccgtt aggatatttt cattcgttgt cgaagcaatt tctgctaaaa
    69361 agatggagta gtcgccgtac acataaggct ggttcgaacg agtgaaataa ctatgaacac
    69421 tatgtcccat ttcgtggaca agcgtaaata gctgatccag cgtatcatgc caattcaata
    69481 aaatatatgg atttgtgtca tagcttcccg aagaataagc atcgcttcgt ttccctttat
    69541 tttcgacaac atcgatccaa cgttcagaga atgctttttc tacgatggcc atgtattctt
    69601 cacccattgg tttcagtgct tctaaagctt tttcttttgc ttcttcgtac gtaaaggtaa
    69661 ttggagcttc ccctaagacc ggtgtataaa gatcatacat gtgcagtttt tccacttcta
    69721 ataaacgttt ccgtaattcc atgtatcgat gtaacaaagg caaatgcttg tttaccacgt
    69781 ctaccaaagt atcgtataca ctttcaggaa tatgattatt gctcaaagac gcttctctgg
    69841 cagagctgta attacggact ttcgctttaa aattatgtcc ttttatatgt gtgcctaaag
    69901 tagaagcaaa tgtatttcta aattgttcgt aaacactgta caatccctta aatgctgctt
    69961 cgcgcaccct tcgatccgtg ctttctagca actgaccata cacgccatga gataattgga
    70021 ctatttcacc attttctcct tcaatcgttg gaaaaactag atctgcatta ttcaaaacag
    70081 caaatgtatc acttgaagca tcaaagattt cacctgctcc agcaagaaga gattcctgct
    70141 cagcagataa gacatgggct cgattatcta ctatttgctg gatataatgg cgatagactt
    70201 ccaattttgg ttcttctttg aaatattgcc aaatctggtc atctgacaat tgcaatattt
    70261 ctggttcaaa ccaggaaacg gcttcactaa ctttcgaaaa cagactgctt gctcttgcat
    70321 aaagcgcttg gtaatctgta tttccagtgt cttgatcgtt tttaaggtgc gcatatacat
    70381 aaatgacttc agtttggcga taaaccctca atacgaattc aatcgcattt aaaaattgag
    70441 aagcgccttg atcaagtgtt cctttgtgtt tttcagattg ttttaactct tctgataatt
    70501 ccaaatattt ctcatcaaac tcttggtcgc ttgaaaagat cttggtcaag tcccaagtta
    70561 aattttcagg caattcttct cgttttggca actgctttac ttccatgaaa tccactcctt
    70621 ttcttccctt agctctatct atcaaaatag atcatagtct aacatccaca tgtcacagca
    70681 tctaactttt ctactcattc atgtgtctgc ttccatcaat tttagcataa ctaaatcttg
    70741 ttttacatag aaaaccgatt cctagcctat ttttatactt actatttttt caaagaagac
    70801 aagtgtatgc attcgttaaa aaactgctga tagaccatct cttcatcaat cataggaaaa
    70861 agccattccc ttttatgttc ttttatttgg caaagccatg agttgaaatc aggaactttc
    70921 tggttttcca aggcttcttc gtacaacatt cgataaagaa aaacctgttc ttgtaaataa
    70981 aagaaaaacc gacttttttg atagatccac gatgatagat gcaaaagatg tttatgacgc
    71041 aagtagcatt gttcttgtat ggatactgta ttcttttgct tgtgaataag ttggcgtgtc
    71101 agccatttct tcccatcttc actcactttt tctatttttt tcatttggtt cattttaatt
    71161 tcgttactag tgaatatttc tttaaggtcc ctactagaaa aagtccagca gctactgcaa
    71221 aaggaaatat gccctgatac agtctctgta atatgatgat acaaataaag cttttgtttc
    71281 ttgagatcag ctttccagca atgcactcct ctttttctat tatagtagca gcaacttttt
    71341 tctatcaatg agaattgcga ttgtccaaga aaagaattac caagtatcca ccatacttgg
    71401 taactgttat tcaaataatt ttgggttctt tcaataaatc tctggtgaga cagtctagaa
    71461 cattggattt ctattgctag attcgccaac aaaatatccg gcctttgccg caacctcggc
    71521 aaataggctt ccaaaaatac tggttctact gactgtccca gccaatccat gaagcattcc
    71581 tttaactgta agtgctcttt tgattctctt tcactaaaga ccgaacagtt atctgatttt
    71641 tgatgggcaa aatgagcaca ttttttcttt ccctttttca aaatcactct ttttcgacag
    71701 ccacgacaat aatatttctt tcctttttct gcatgtttag caaaacagca cttattatat
    71761 tcattcattg caagcagcat ttttctccct ctgaacttat ttacgtctaa gaatttattt
    71821 acacgaaaaa agagggcgtg aaaaagctat tctgcatcaa gtaataagaa cagctaaaca
    71881 aaaatagttc ccaatatttt tcgtttggtt gggcttgtta ccgcagatgc aagcttttga
    71941 acacatttat acgaaaaaaa gactgcgaca caatttttgt cacagtctct tactataatg
    72001 ctgatttata caaaataaaa tttcgttcgc tcgatagcat tacgcgccat cagacattgt
    72061 ccatattcat tcaatgtttc tggtgtacga tcgctctttt cagcaaactc caaaattcga
    72121 gcaatctgat tctctacatc cgcttggttg agattttcca tccagaagtg aacgactagg
    72181 taatagcgct cttcgaataa atacaaatca gtccaagcag actctagttc gacatctgtt
    72241 gcaagttgga tcacttgttc aaaatcttca aaagcaaaag ttgcttgtct ttcctgttct
    72301 tctagggcgc ttccagataa ttcttcctcc ggatcgctgc caataatctg ctgacgaaga
    72361 aagtcactca catcttctga atcaacagta gaatcttctg attgagaaat ttcttcatcc
    72421 ggaagatttt tactgataaa cagttctaat ccgtctcctt ttggcaaaac ttggaaagtg
    72481 acagcttcgc ttcctcggaa ctcctcttcg atatcaactt cttccaaaat actataaaag
    72541 aaattttcga tttctttgtg attgccaagt aaatccaaaa atgaaacgcc ccgttcctct
    72601 aaatcttcat gaccaattag tacacggatc gtattttcat taatatgttc catttccatt
    72661 ttgctacacc tcactttgcc acaatgttta atatagattc attgtagcga aatcagctta
    72721 aatgtaaaga aaaaaaatct cgctgttaag cgaatttaat aaaaccagcg gatttttcaa
    72781 cctttcaagc tatcttattt aactataaca tttttggcag acgaatacta tatagccgac
    72841 ttttcagcta attttccctc tctatttttc gtgcaatcat catcttctac taccttttta
    72901 tacatctaat caagaatact ttttgtaaaa acaaaaaaac ttggaaaaac tatctttgta
    72961 atagt
//
LOCUS       DAZULR010000010        71110 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.010, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000010 DAZULR010000000
VERSION     DAZULR010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 71110)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 71110)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..71110
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.010"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            11..241
                     /locus_tag="ACG8ZV_000717"
     CDS             11..241
                     /locus_tag="ACG8ZV_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 family protein"
                     /protein_id="HFS4996082.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            338..1639
                     /gene="murA"
                     /locus_tag="ACG8ZV_000718"
     CDS             338..1639
                     /gene="murA"
                     /locus_tag="ACG8ZV_000718"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFS4996083.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1652..1828
                     /locus_tag="ACG8ZV_000719"
     CDS             1652..1828
                     /locus_tag="ACG8ZV_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFS4996084.1"
                     /translation="MSNQRYILLTLIKILMVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            1963..2259
                     /gene="yidD"
                     /locus_tag="ACG8ZV_000720"
     CDS             1963..2259
                     /gene="yidD"
                     /locus_tag="ACG8ZV_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HFS4996085.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            2444..2911
                     /locus_tag="ACG8ZV_000721"
     CDS             2444..2911
                     /locus_tag="ACG8ZV_000721"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4996086.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            2996..3880
                     /locus_tag="ACG8ZV_000722"
     CDS             2996..3880
                     /locus_tag="ACG8ZV_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFS4996087.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            3994..4230
                     /locus_tag="ACG8ZV_000723"
     CDS             3994..4230
                     /locus_tag="ACG8ZV_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HFS4996088.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4318..4398
                     /locus_tag="ACG8ZV_000724"
     tRNA            4318..4398
                     /locus_tag="ACG8ZV_000724"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4352..4354,aa:Tyr,seq:gta)
     gene            4405..4476
                     /locus_tag="ACG8ZV_000725"
     tRNA            4405..4476
                     /locus_tag="ACG8ZV_000725"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4437..4439,aa:Gln,seq:ttg)
     gene            4601..4771
                     /locus_tag="ACG8ZV_000726"
     CDS             4601..4771
                     /locus_tag="ACG8ZV_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996089.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVRVKSKRP
                     TNHTKKWMAKNR"
     gene            4991..5698
                     /locus_tag="ACG8ZV_000727"
     CDS             4991..5698
                     /locus_tag="ACG8ZV_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFS4996090.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(5757..6401)
                     /locus_tag="ACG8ZV_000728"
     CDS             complement(5757..6401)
                     /locus_tag="ACG8ZV_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HFS4996091.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDEAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGIPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            6527..6814
                     /locus_tag="ACG8ZV_000729"
     CDS             6527..6814
                     /locus_tag="ACG8ZV_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996092.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            6922..7242
                     /locus_tag="ACG8ZV_000730"
     CDS             6922..7242
                     /locus_tag="ACG8ZV_000730"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFS4996093.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            7323..8636
                     /locus_tag="ACG8ZV_000731"
     CDS             7323..8636
                     /locus_tag="ACG8ZV_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HFS4996094.1"
                     /translation="MNHFWGRRLLTRDIKAIDCEEVNLPNYEKIAAVERLSNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEISKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKIL"
     gene            8633..9352
                     /locus_tag="ACG8ZV_000732"
     CDS             8633..9352
                     /locus_tag="ACG8ZV_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HFS4996095.1"
                     /translation="MRCSCCSKDIVQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVNSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQIAQPKIIRTISLAR"
     gene            9480..10031
                     /gene="raiA"
                     /locus_tag="ACG8ZV_000733"
     CDS             9480..10031
                     /gene="raiA"
                     /locus_tag="ACG8ZV_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HFS4996096.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTANAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            10253..12787
                     /gene="secA"
                     /locus_tag="ACG8ZV_000734"
     CDS             10253..12787
                     /gene="secA"
                     /locus_tag="ACG8ZV_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0017038 - protein import [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HFS4996097.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKSFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            12913..14014
                     /gene="prfB"
                     /locus_tag="ACG8ZV_000735"
     CDS             join(12913..12984,12986..14014)
                     /gene="prfB"
                     /locus_tag="ACG8ZV_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HFS4996098.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            14119..14805
                     /gene="ftsE"
                     /locus_tag="ACG8ZV_000736"
     CDS             14119..14805
                     /gene="ftsE"
                     /locus_tag="ACG8ZV_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HFS4996099.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            14798..15682
                     /gene="ftsX"
                     /locus_tag="ACG8ZV_000737"
     CDS             14798..15682
                     /gene="ftsX"
                     /locus_tag="ACG8ZV_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HFS4996100.1"
                     /translation="MIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFMAVI
                     MNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELKKIQ
                     NEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSDRIF
                     QIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRWPFF
                     LEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMVGIG
                     VIIGSLGSIISMRRFLKF"
     gene            15834..17282
                     /gene="cls"
                     /locus_tag="ACG8ZV_000738"
     CDS             15834..17282
                     /gene="cls"
                     /locus_tag="ACG8ZV_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HFS4996101.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWVLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHSTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            17619..18476
                     /locus_tag="ACG8ZV_000739"
     CDS             17619..18476
                     /locus_tag="ACG8ZV_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HFS4996102.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            18591..19511
                     /gene="pstC"
                     /locus_tag="ACG8ZV_000740"
     CDS             18591..19511
                     /gene="pstC"
                     /locus_tag="ACG8ZV_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HFS4996103.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTITTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            19511..20395
                     /gene="pstA"
                     /locus_tag="ACG8ZV_000741"
     CDS             19511..20395
                     /gene="pstA"
                     /locus_tag="ACG8ZV_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HFS4996104.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            20410..21216
                     /gene="pstB"
                     /locus_tag="ACG8ZV_000742"
     CDS             20410..21216
                     /gene="pstB"
                     /locus_tag="ACG8ZV_000742"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HFS4996105.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            21232..21990
                     /gene="pstB"
                     /locus_tag="ACG8ZV_000743"
     CDS             21232..21990
                     /gene="pstB"
                     /locus_tag="ACG8ZV_000743"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HFS4996106.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            22003..22680
                     /gene="phoU"
                     /locus_tag="ACG8ZV_000744"
     CDS             22003..22680
                     /gene="phoU"
                     /locus_tag="ACG8ZV_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HFS4996107.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            23257..23949
                     /locus_tag="ACG8ZV_000745"
     CDS             23257..23949
                     /locus_tag="ACG8ZV_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HFS4996108.1"
                     /translation="MLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLLNISIL
                     FVVIGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYL
                     TRPYRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQVGRDVI
                     GSMTNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVLSIPIS
                     VLFFLTVRRLKR"
     gene            23946..24713
                     /locus_tag="ACG8ZV_000746"
     CDS             23946..24713
                     /locus_tag="ACG8ZV_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HFS4996109.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            24813..26381
                     /gene="liaX"
                     /locus_tag="ACG8ZV_000747"
     CDS             24813..26381
                     /gene="liaX"
                     /locus_tag="ACG8ZV_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HFS4996110.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEIAQVQL
                     STTTGSIYLKDTDK"
     gene            26678..26998
                     /locus_tag="ACG8ZV_000748"
     CDS             26678..26998
                     /locus_tag="ACG8ZV_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0080135 - regulation of cellular response
                     to stress [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HFS4996111.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            26998..27348
                     /locus_tag="ACG8ZV_000749"
     CDS             26998..27348
                     /locus_tag="ACG8ZV_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HFS4996112.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            27515..28453
                     /gene="hprK"
                     /locus_tag="ACG8ZV_000750"
     CDS             27515..28453
                     /gene="hprK"
                     /locus_tag="ACG8ZV_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HFS4996113.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANKNGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            28468..29298
                     /gene="lgt"
                     /locus_tag="ACG8ZV_000751"
     CDS             28468..29298
                     /gene="lgt"
                     /locus_tag="ACG8ZV_000751"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HFS4996114.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            29342..30367
                     /locus_tag="ACG8ZV_000752"
     CDS             29342..30367
                     /locus_tag="ACG8ZV_000752"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HFS4996115.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGIGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            30382..31320
                     /gene="galU"
                     /locus_tag="ACG8ZV_000753"
     CDS             30382..31320
                     /gene="galU"
                     /locus_tag="ACG8ZV_000753"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFS4996116.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKTLEAEGSKIDHNPKGITEIKEEKKK"
     gene            31445..31885
                     /locus_tag="ACG8ZV_000754"
     CDS             31445..31885
                     /locus_tag="ACG8ZV_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HFS4996117.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            31888..32490
                     /locus_tag="ACG8ZV_000755"
     CDS             31888..32490
                     /locus_tag="ACG8ZV_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HFS4996118.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDSKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(32549..33655)
                     /locus_tag="ACG8ZV_000756"
     CDS             complement(32549..33655)
                     /locus_tag="ACG8ZV_000756"
                     /EC_number="3.4.11.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HFS4996119.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLTSIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            33865..34866
                     /gene="ccpA"
                     /locus_tag="ACG8ZV_000757"
     CDS             33865..34866
                     /gene="ccpA"
                     /locus_tag="ACG8ZV_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HFS4996120.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(35203..37548)
                     /locus_tag="ACG8ZV_000758"
     CDS             complement(35203..37548)
                     /locus_tag="ACG8ZV_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HFS4996121.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAK
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            37827..38729
                     /locus_tag="ACG8ZV_000759"
     CDS             37827..38729
                     /locus_tag="ACG8ZV_000759"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HFS4996122.1"
                     /translation="MLLGSHVSMSGKKMLLGAAAEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQIFDPEVFPELLAEEVIL"
     gene            38942..40717
                     /locus_tag="ACG8ZV_000760"
     CDS             38942..40717
                     /locus_tag="ACG8ZV_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HFS4996123.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVKKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(40783..42369)
                     /locus_tag="ACG8ZV_000761"
     CDS             complement(40783..42369)
                     /locus_tag="ACG8ZV_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HFS4996124.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETVEEIE"
     gene            42620..42844
                     /locus_tag="ACG8ZV_000762"
     CDS             42620..42844
                     /locus_tag="ACG8ZV_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HFS4996125.1"
                     /translation="MLSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            42985..44736
                     /locus_tag="ACG8ZV_000763"
     CDS             42985..44736
                     /locus_tag="ACG8ZV_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter transmembrane domain-containing
                     protein"
                     /protein_id="HFS4996126.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGVFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSVKIIFGWIFLLIIAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTK
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIVMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPVKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     QMWEKQQLEAKIEGGEA"
     gene            44736..46520
                     /locus_tag="ACG8ZV_000764"
     CDS             44736..46520
                     /locus_tag="ACG8ZV_000764"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4996127.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRTTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVLVKSIIWFFQWYLYSM
                     ASLKTYQYIRVKLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSIFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQMITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGI"
     gene            46846..47697
                     /gene="licT"
                     /locus_tag="ACG8ZV_000765"
     CDS             46846..47697
                     /gene="licT"
                     /locus_tag="ACG8ZV_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HFS4996128.1"
                     /translation="MLIEKVLNNNVVITRDERDREMIVMGKGLAFKKKVGDPILDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVHLNDSVYISLTDHLY
                     TAIERQKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GAKSEDGEVSEELFQVIQKKYKDTFGCVEKIADFLTGAFDYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            47793..49673
                     /locus_tag="ACG8ZV_000766"
     CDS             47793..49673
                     /locus_tag="ACG8ZV_000766"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFS4996129.1"
                     /translation="MGKYQELAENIVKNIGGKENIRSLTHCVTRLRFKLKEENKAKDD
                     VLKKMEGIVTIMKSGGQYQVVIGNHVPDVYAEVLTVAGISDEAEEEVSSSSNLFNRLI
                     DILSGCFQPFLGALAAAGMVKGLNALFLFLKFYTEGSGTYIMLNGIGDAIFYFMPVIL
                     GYTAAKKFHLNPMVGLVIGAALCYPTVQGAALQSGFPDGSPAPYSLLGLPAYETFLGI
                     PWVGSSYTSSVVPVIFIIAFAGQVQKIAKKWIPAVVQTFLVSFSVLLIALPAGFLIIG
                     PIVSILTDLLSTGFQALMDFSPAVYGAVLGFLWQVLVIFGLHWSIIPLAIMQLAQNGW
                     SQMLVGVYGASFAQTAVVLAMYFKFKDQKMKALCMPAVISGIFGVTEPAIYGITLPKK
                     KPFIYSMIGGAVSGIYLMASGTISYIMGGLGIFGVVNYITETDASGMFQAFIGIAIAS
                     VIGFSLTFFFWKDEAGETDAIQKKSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGRGI
                     LIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSETGLELLIHVGLDTVQLEGKYFESLVQ
                     QGERVRQGDLLLRFDKKKIEKEGYSLETPVIVTNYTDYLDILENQGETVGPDDALITA
                     LT"
     gene            complement(49713..50615)
                     /locus_tag="ACG8ZV_000767"
     CDS             complement(49713..50615)
                     /locus_tag="ACG8ZV_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFS4996130.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQAIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIHDTLSLIHHDQLQKAKYLLLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNDVPILALTSIGDST
                     LSAMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVE"
     gene            50846..52249
                     /locus_tag="ACG8ZV_000768"
     CDS             50846..52249
                     /locus_tag="ACG8ZV_000768"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008706 - 6-phospho-beta-glucosidase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HFS4996131.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLSADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKEEGIEVQ
                     DELARELSGNTHIMEEV"
     gene            52249..53682
                     /locus_tag="ACG8ZV_000769"
     CDS             52249..53682
                     /locus_tag="ACG8ZV_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HFS4996132.1"
                     /translation="MGFRKDFLWGGATAANQCEGAYDEGGRGLANVDVVPIGKDRFPV
                     ITGKKKMFEFDEDHFYPAKIAIDMYHRYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNEAGLKFYEDVFKECQKHGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIEMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFASV
                     KNPYLQASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNQGNG
                     TLARSKKKSFNWYKKVIDSNGENLSNN"
     gene            53827..54753
                     /gene="trxB"
                     /locus_tag="ACG8ZV_000770"
     CDS             53827..54753
                     /gene="trxB"
                     /locus_tag="ACG8ZV_000770"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HFS4996133.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYESVSRFGTENAYGIVQDIKDHGSHKEVICEDKSYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNMPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            54967..56694
                     /locus_tag="ACG8ZV_000771"
     CDS             54967..56694
                     /locus_tag="ACG8ZV_000771"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HFS4996134.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAKHSGLITIIGEEVDAAYLEEIKAV
                     TIDRELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPDGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYFAEKTISVTMSGQEGSAKISALMEKFRKEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGSSTEDAAEKVASYE
                     AIIKKMTEE"
     gene            56709..57059
                     /locus_tag="ACG8ZV_000772"
     CDS             56709..57059
                     /locus_tag="ACG8ZV_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HFS4996135.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKSKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(57151..58011)
                     /locus_tag="ACG8ZV_000773"
     CDS             complement(57151..58011)
                     /locus_tag="ACG8ZV_000773"
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, water dikinase regulatory protein"
                     /protein_id="HFS4996136.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLRQALQDALEEKALVLHTLINQELIEITRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEKSD"
     gene            58103..58531
                     /locus_tag="ACG8ZV_000774"
     CDS             58103..58531
                     /locus_tag="ACG8ZV_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFS4996137.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGKIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            58693..58869
                     /gene="rpsU"
                     /locus_tag="ACG8ZV_000775"
     CDS             58693..58869
                     /gene="rpsU"
                     /locus_tag="ACG8ZV_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HFS4996138.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            58896..59342
                     /locus_tag="ACG8ZV_000776"
     CDS             58896..59342
                     /locus_tag="ACG8ZV_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HFS4996139.1"
                     /translation="MSLLSRLNDDMKAAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(59496..60875)
                     /gene="brnQ"
                     /locus_tag="ACG8ZV_000777"
     CDS             complement(59496..60875)
                     /gene="brnQ"
                     /locus_tag="ACG8ZV_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HFS4996140.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGSNWI
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYDSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFQPMGNLNQSAADSYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKSPFVYQVTMFFSAVPAVLDM
                     LANSPALVSQQTVVASLLGFYHHYVPFAALGLGWVVPTLLGYAGSLLFYYVYRVSGYK
                     QEASELPEE"
     gene            61581..62552
                     /locus_tag="ACG8ZV_000778"
     CDS             61581..62552
                     /locus_tag="ACG8ZV_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HFS4996141.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            62576..64768
                     /locus_tag="ACG8ZV_000779"
     CDS             62576..64768
                     /locus_tag="ACG8ZV_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing metalloprotein"
                     /protein_id="HFS4996142.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIICGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQKRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDAINKSYDEKIDKAKEDENIPKPTTEERIAALKKNFENVNAENVVFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEEQIQYLNVTPAQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            64785..65261
                     /gene="ybeY"
                     /locus_tag="ACG8ZV_000780"
     CDS             64785..65261
                     /gene="ybeY"
                     /locus_tag="ACG8ZV_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HFS4996143.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            65245..65640
                     /locus_tag="ACG8ZV_000781"
     CDS             65245..65640
                     /locus_tag="ACG8ZV_000781"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFS4996144.1"
                     /translation="MDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            65655..66554
                     /gene="era"
                     /locus_tag="ACG8ZV_000782"
     CDS             65655..66554
                     /gene="era"
                     /locus_tag="ACG8ZV_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HFS4996145.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            66697..67509
                     /gene="recO"
                     /locus_tag="ACG8ZV_000783"
     CDS             66697..67509
                     /gene="recO"
                     /locus_tag="ACG8ZV_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HFS4996146.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            67893..68810
                     /gene="glyQ"
                     /locus_tag="ACG8ZV_000784"
     CDS             67893..68810
                     /gene="glyQ"
                     /locus_tag="ACG8ZV_000784"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HFS4996147.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENVKEAE"
     gene            68812..70887
                     /gene="glyS"
                     /locus_tag="ACG8ZV_000785"
     CDS             68812..70887
                     /gene="glyS"
                     /locus_tag="ACG8ZV_000785"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HFS4996148.1"
                     /translation="MAKDLLLEIGLEEIPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEIIPFEILDVKTDRASRGHRFLGEDVTFTHAKQYEEKLNEQFVIASPQKR
                     KEMIITQANELAEKNHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDTDRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEA
                     MKTSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
BASE COUNT        23264 a        12453 c        15229 g        20164 t
ORIGIN      
        1 ggacgtcatt atgcaagtat acggaattga tgcggtgctt cgaatcgtga gtcatttggc
       61 gtttatctac ttagccttct ggtctttacg ttcgttacgc attgaaactt ttttcagacc
      121 aatgcataat acgcaaatta gaatggcaat cgtacttttt tcaatttttt tagggtacac
      181 tgcaagtaat tttttcttag aagttatcgc tttatgccga aatcttttcg ttagcctgta
      241 aattttaaaa aaaggtacta ttttaaaagc aaggatgtta taatagaaaa gattttgagt
      301 aagtgtatgc tcattggaat tttttggagg gaacaacatg gaagagatca tcgtaagagg
      361 tggcaatcaa ttaaatggaa cagtaagaat tgaaggagct aaaaatgctg ttttgcctat
      421 tttagctgct agtttgttag cagaagaagg tattacgaca ttagacaacg ttccgattct
      481 ttctgatgtc ttcactatga atcaagtgat tcgtcactta aacgtagatg tagattttga
      541 tgaacaaaag aatcaagtaa caatcgacgc ttcaagacaa ttagaaatcg aagcgcctta
      601 tgagtatgtt agtcaaatgc gtgcttcaat cgttgtgatg ggtccgctac ttgccagaaa
      661 tggacatgca aaagtagcta tgcctggtgg atgtgcgatt ggtaaacgac caatcgattt
      721 gcatttaaaa ggatttcaag ctttaggagc aaaaattatt caaaaaaacg gctatatcga
      781 agcaattgcg gatgaattga tcggtaacac gatttattta gatttcccta gtgtaggtgc
      841 tactcaaaat atcatgatgg ctgccgtaaa agcaaaagga acaaccatca ttgaaaacgt
      901 agctcgcgaa ccagaaatcg ttgatttagc aaacattttg aataaaatgg gcgctcaagt
      961 ctatggagct ggtactgaaa caatgcgtat tgaaggcgtg gatcatttac atgcagtcaa
     1021 ccactcaatc gtacaagatc gtatcgaagc aggtaccttt atggttgctg ctgcaatgac
     1081 acaaggcaat gtgctgattg cagatgctat ctctgaacat aaccgcccat tgatttctaa
     1141 attgatcgaa atgggtgcag aaatcattga agaagaaggc ggagtccgtg tcatcggacc
     1201 aaaacatatc ttacctacag atgtaaaaac gatgcctcat cctggtttcc ctacagatat
     1261 gcaagctcaa atgacagcta tccaattagt tgcagaaggt acaagtgtag tgactgaaac
     1321 agtgtttgaa aatcgtttcc aacatttaga agagatgcgc cgtatgaacg ctcatgtcaa
     1381 aatcgacgga aatgtagcaa tcatggatgg aaaccatgaa ttgcaaggtg cagaagtata
     1441 tgcaacagac ttgcgggcag cagcagcatt agttttagct ggcttgaaag caaatggaat
     1501 cacacgtgtg cgtaacttga attatctaga ccgtggatat tataatttcc atatcaaact
     1561 acagcaatta ggtgcagacg ttgaacgtgt agacatggat caaacttctg ctgaaaaaac
     1621 agcacaaacg attgcttaag gaagtggctg aatgagtaac caacgatata tcttattaac
     1681 tttgataaag attttaatgg tgatcttatt gcttatcctt ctttttgtgg ccggaacgat
     1741 gatcggatat ggtgtcatcg gtggcggcaa tccatttaaa gtatttcagc caagtttgtg
     1801 gattcatatt cgagactttt ttcattgata aataagaatc acagtggttc tagtcgatat
     1861 gaagtgagcc atgaagcaga acatgataaa agaaaacaga agggaacgtt gacgttagtc
     1921 gcgatccctt tttttagtaa aagaaaagaa ggaatctaat tgatgaagaa gatattgatt
     1981 tatttagtta gaggatatca gcgctttatt tcgcctgcat ttccacctag ctgccgttat
     2041 tacccaacct gttccaatta tatgataaaa gcaattcaaa cccatggcgc gctaaaaggg
     2101 acggtaatgg ggactgcacg gatcttacgc tgtcatcctt ttgtcaaagg cggtatcgat
     2161 tatgtaccat tgacattccg attaacgcga aataagaaag ataaaaaaga accagattat
     2221 aaaaaggttg tgaaaaatac gggtagcact gagcgataaa gaaacaattt ggaaaatagc
     2281 ttcttatatt ttgcaaaatt gtgagttatt gccgaagtgt tggattttga acaccgtcaa
     2341 aaaaaaggtt gtgaaaaata cggctagcac tgagcgataa agaaaaagag gaaatttatt
     2401 gtcaaagtaa caactccgca actacttata tgggggacaa aaaatgatcg aagaactaaa
     2461 caagaaagat ttaccatggt ccttgttatt agatgcagat cctgataaag aaaaagttca
     2521 agtatatgtt tccagaggga gtggctggat atggaaagaa aaagaaaaaa caataggtgt
     2581 actgatctat gtggcaaggg aaaaagaata cgaaatcgtc aatgtagcag taaccccaac
     2641 gtatcaagga aaggggattg gcggaaaatt acttgagaca gcttttcaga agctttcaca
     2701 actcgcttcc agtcaaactc agatcatcat acgaaccggc agtactagca gtgcggcgtt
     2761 acatctctat caaaaaatgg gctatgtgga gattggtcga gtcaaagact attttatcca
     2821 tcattactct gagcccattt ttgaaaatgg agatcaatta agggatcaag tgattttagc
     2881 aattcactta cctaaaaata gctttaacta ataaaatttc aattcaagaa aatgctttca
     2941 aatgctaaat agatacatta caatagcttt agcaaacaaa aaggagaata tttttatggg
     3001 aatattagtt tttgattttg gtggatcggc tgtcaaatat ggttgttggg atggcaaaga
     3061 gattaaaggt aagggacaat ttgcaacgcc tgaatcttgg gaagaaatga aagcgcaatt
     3121 atttcaagtt tataaaaaaa tactcgtttc ttttgaagtc gaaggaattg gaatcagctc
     3181 tcctggagta gtgaataatg agaaacaggt gattgaggga atcagtgcga ttccttatat
     3241 tcatggattt aatattttcc gagatttgga aactctgttt caacttccag taacgattga
     3301 aaatgacgcc aactgtgccg gaatggctga attttatgaa ggtgctgccc gcgattatca
     3361 agatgttgct tttgttgtgg caggaactgg gattggcggg gcgttgttca cgaaaggaca
     3421 aatcaataaa ggggcacatc tttacggtgg agaatttggg ttgatgttct taaatggcga
     3481 taagacattc agtaaacttg gtacagcggt acagatggct tggcgttatt gtgaacgcaa
     3541 aggtctcgat aaaaatgctt ataccggaaa agatgtcttt gaattagcag aaactggaga
     3601 tgcaatagca aaagaagaag ttgagagttt ttatacgtat cttacaaagg gattattcag
     3661 tattcaattt tcgtttgatc cagaagtgat cgtattaggc ggcggggttt ctgcaaaaga
     3721 agggctcatt gatgagatca aaagccgaat gaagaagctg acagaacaat tcgatctgca
     3781 tgatttcgaa ccgcagattt tattatgtga atacagaaac gatgctaatc ttgtaggtgc
     3841 agcagcaaac tatctcgctg tacgtcaagg ggagaattaa gagctttaga gaaggtgcag
     3901 cttgcataaa agaagtgaat gaaatgaata ggagattttt acctaaggaa tgttttattt
     3961 gctgcagtat gataaaatat ctgagaggtg aaaatgatgt caaaaaaaaa taaagatatt
     4021 gaagtgcgta tagaagaagt gaaaaaagat atcaaaggta agaattatga agtcactcag
     4081 ttatttatag ggaaaaaaat gattggtgag atcttagcct atggaccaaa agaatatgaa
     4141 attttctttg gtgaagaaga ttttggaaaa gaaaaaagtc ttgaaaatgc gatagaaaca
     4201 gtgattcgac actggaatct gcacgaataa aaaaatatca aaaaaacttt caataaaggg
     4261 ttgcaaaaat ctggaaaatt aggtattata actaagtcag gttgatacaa acctttcgga
     4321 ggagtagcga agtggctaaa cgcgacggac tgtaaatccg ttccttaggg ttcagtggtt
     4381 cgaatccact ctcctccatt tcattggggt atagccaagc ggtaaggcaa gggactttga
     4441 ctccctcatg cgttggttcg aatccagcta ccccagtata ccacaatcgt aagctctcgt
     4501 tagttcgaga gctctttttt ttgctttgct accttgttcc ttgaagattc tgctgattta
     4561 agatagagtt aagttaacta caagaattgg agggatccac atgaaatgga aagaaaaagt
     4621 agacgaagca gctgaaaagt tatatgattt ggtcaaatca gaaaaataca atattgaagt
     4681 gaatattccg aaaaaaggcg gaaaagcggt ccgggtaaaa tcaaaacgcc caacgaatca
     4741 tacaaaaaaa tggatggcta aaaaccgcta ataataacaa aagatccata agtcggcatt
     4801 ttcatcgatt ttagggtctt ttgttatttt ctaggttgga catatctaaa aaattgtttc
     4861 tgacaatagg agtaggaaga acgatgtgtg tctaaatcct ctgttgatgg atagaaacct
     4921 ttatcttttt cagttgtgaa tcaggtatat accagttata atagaagaaa cgaaaggacg
     4981 ggtgtacgtt atgtcgaatc aattacctgt atatatacag attcatgacc aattaaaaaa
     5041 tgaaatcgaa caaggtatat ggaaagtcgg agaccgtctt ccttcagaaa gagaattagc
     5101 agtgaaattc aatgtcagcc gtatgacgtt gagacaagca attcaaaact tggcagatga
     5161 aggaatctta gaaagaaaga tcggttcggg tacatatgtt gcacgagaaa aagtacaaga
     5221 aaaaatgtct ggtgcaacaa gttttacaga aattatggaa tcacaaaatc gagtaccgtc
     5281 tagtcggaca atctcttatt tcttgacttc gccaagctca agtgaaatgg aaaaactaaa
     5341 cttgagtaaa gatgacacga tcttgcgaat ggaacgtatt cgtttcgcag atgatgtccc
     5401 tatttgtttt gaagttgcca gtgtgccaca aaagctgatc gatggctaca gcaaagcaga
     5461 gattactgaa tcgttgtatc gcacgctaga agaaaaaggc gggaaaaaga tcggtccagc
     5521 gaatcaaacg attactgctg tgttggcttc tgagaaaatt gctgactatt tagaggtaaa
     5581 acgaggagat gcagttcttc gtttgcgcca gatttcttat tttgaagacg gtacgccgtt
     5641 tgagtatgtg cgtacgcaat acgtaggaaa tcgttttgag ttttatttgg aaaaataaaa
     5701 aacaggtgat ccctgattcc gtattagaaa taaaagagaa tcagaatcac ctgtttttat
     5761 atatgatcag ttaccagttg ctcgtgataa gaaacaggac cctcttcaaa ttggacttgt
     5821 ccgttcagca gctcaatgat ggattcttta aagtggtcag cacttttttc atctacagca
     5881 cagatgacgc taacttgatc agtatattgg atttctttta taaaaaaatg ttggagttca
     5941 agataattct gtaattttcc tagttgcgga tacgtgatca tcacagagat ctcctgttgc
     6001 aaggtacctt ctacgattcc aatgtcagac aatgcttgag agaccgcatg agtgtatgct
     6061 cgtattaatc cgcctgtgcc gagtttcgtt cctccaaaat atcgagtgac tactgcagct
     6121 acattgatca gttgattttt tttgaggact tccaacatcg gtatgcccgc cgttccactt
     6181 ggttctccat catcgctgct tcgctggatt tcattttttt ctccaatgat gaaggcgctg
     6241 cagttatggt tcgctttcca atgttctttt tttatttctt gaatgaaact ttttgcttcg
     6301 tcctctgatt ctattcgtct aagagaacag ataaagcgtg attttttgat ctcgatctca
     6361 ctttgtccat tttcttttat tgtacgatag cgctcgatca tcttgtcacc tcttttttca
     6421 ttttctttat tcagtataaa taaagttcta ggttgtttca acactgtaac ggttgcgcaa
     6481 ttgctgtagt atgcgataat aaagacaaag gcaggtggat ctggggatgc aggaacgaat
     6541 gaaaaagtac gatgcaatta cgcattattt gaagaacaat ggcggctctc aagtaacgtt
     6601 gacctttacc caatttgacg aactgctgtt tcccagtaac ggacttccca aaacagcaag
     6661 ggaaagtaca gattggtggg caaatgatta taaacaccct gaaaaaggtg cctatggctg
     6721 gataaatgca ggctatgaag tagttgtcat caatttggac aaagaatatg tcgtgttcaa
     6781 taaattagtg aaatctagtt ggctatttga ttaaataaac cgcgtttaga aaacgttgac
     6841 aaatttcttt ctttttatat aatagagtaa cagacgcgaa gaaaacgttt gcgtagtttg
     6901 ttttaaaaag gagagaaaag tatggctaaa aaaacaatca tgcttgtatg ttcggctggt
     6961 atgagcacaa gtttactagt aacaaaaatg caaaaagctg ctgaagcaaa aggaatcgac
     7021 tctgatattt tcgctgtgtc cgcttctgac gcagataaca atcttgcaaa taaagacgtg
     7081 gatgtgttgt tattaggccc acaagttcgc tttatgaaag ctgattttga gaaacgtctg
     7141 gaaccaaaag gcattccttt agatgtcatc aatatggctg attatggtat gatgaatggc
     7201 gaaaaagtgt tagatcaagc aatcacgctc ataggtgaat aaatagaaca gtataactat
     7261 cgaacaagcg atccaaaaaa tagatcgctt gttttttcgt atattttttt agggcgaata
     7321 atatgaatca tttttggggt agaaggcttc tgacgagaga tattaaagca atagactgtg
     7381 aggaggtaaa tttaccaaat tatgagaaga tcgcagcagt ggaacgtttg agcaactgga
     7441 ttctttgtca tcgctgtgga atgagaacgt ccgtcattga tggacagctt gcagattacg
     7501 gttatttttg tacacattgt ctatatttag ggcgatgcga cactcaacaa gatttatatt
     7561 tgtttgatca gcctgaagca aaacctcgag aagtcgtctt tttttggaca ggacagctta
     7621 ctgaaaaaca aacggaaatc tcaaagagaa tactttgcca ttcagaaaaa agacatcatc
     7681 ttatttgggc tgtaacaggt gcagggaaaa cagagatgct ttatcctatt ttagtggaaa
     7741 ctttaaaagc tggaggaaga gtagcgattt gtacaccgcg agtcgatgtt tgtaatgaat
     7801 tgtttttacg ctatcgttat gtttttccag aagaaaaaat cacgttgctc catgggaata
     7861 cagcaacggc ttataccttt acttcttttg ttatctgtac gattcatcag ctataccgtt
     7921 tttatcggtc ctttgattta atagtgatcg atgagatcga tgcgtttcct tataacgggg
     7981 atgcaggatt agctcatgct gtgcaaacag cgattaaacc agacggacga ttcatctact
     8041 taagtgccac acctgataaa aagttactaa aggagatcaa gcagacgttt gacatccaca
     8101 aacttgcttt acgctttcat cggcgtttgc ttcctgaacc cgtcttggtt ttcatgaata
     8161 attggcgaca aaaatgcaag aacaagaaga agataaaatc tttggtgcgg atcattcatc
     8221 aattaattaa agaaaaccat atccttttat tttgtccaag tatcacgatg atgcatcgtt
     8281 tgaaagccac acttcaagag gctcttccga gatatgagat cacagatgtt tcttcaagag
     8341 acaatcagcg ggcggaaaaa gtccagaaaa tgcgagaagc aaaatatgac atactgttaa
     8401 ccacgatgat ccttgaacgt ggagtcacat ttgaaagaat atccgttatc gttttaggag
     8461 cggatcatcc ggtttttact aaatcttctt tggtacaaat cgcaggaaga gccgatcgta
     8521 aagggcctta tacgaacagt caagtatatt ttttctatga agaaaaaact gcagctattc
     8581 gaaaagcttg tcaggaaatc aaagaaatga atgaagaagg gaagaagata ctgtgaggtg
     8641 cagttgctgc agtaaagata tcgtccaaaa tttaacattc agcgagatta ttggtgtttc
     8701 gaaatacaga ttacctcaga cttgttcagt ttgtcgcgca caatttcatt tattggaaac
     8761 aagaggctgt tctggctgtc aaaaaccaat ccatttcaat ctagagagta cgaaaaagaa
     8821 agtaaattct atccccgttt actgcagtga ctgtcaagaa tggaagaaga aatatccgac
     8881 ctatgatttt cagcaccgtg ccttttttgt gtacgatgaa aatatgaagg cctggctcaa
     8941 tcaatacaag tttatgggag atatccgact agcaggcacc tttgcatata aatggacgca
     9001 gataaaaaaa gaatacccga catacatcta ttgtccaata cctttatctg aaaaaaggcg
     9061 aacagaaaga ggattcaatc aagtaagcga gatgttgaaa gcagcaagaa ttccttttca
     9121 gatgctactc aaaagagaga agcatctgct ggctcaagca aaaaacacgc gaaaggaaag
     9181 attggagatg cctcaacctt ttgaacttgc agtcaccttt tctaagatac aaaataaaaa
     9241 aatattgatt attgatgatg tctatacaac aggacagact cttttccacg cagcagattg
     9301 tttgcagatc gcacagccga aaatcatccg aactatttct ttggcgagat gaattagatg
     9361 tggaaatttg atagcgattt aatttgcaaa taacctagag ttcgatataa tagaattaag
     9421 aagagggaaa gagtggtcct tctccttctt gattgtggta gacgaaaggg gtaattttta
     9481 tgtttagata taatgtacgc ggcgaaaata tcgaagtaac tgaagcgatt cgcgactacg
     9541 ttgagaaaaa agtaggcaaa ctagaacgct atttcagtga cgcacccgat gcaacggcgc
     9601 atgtgaactt aaaagtttat acagaaaaaa cagcaaaagt ggaagtaacg atcccattac
     9661 cttatcttgt attacgtgcc gaagaaactt ctccagattt atacgcaagt atcgatttgg
     9721 ttgttgacaa attggaacgc caaatccgca aattcaaaac aaaaattaat cgtaaatccc
     9781 gtgaaacggg catgaatact gcaaatgctg ctgctttatt caatgaagag gacgaaaacg
     9841 aaaatgattc tgaattagat atcgtacgta cgaaacgcct ttcattgaaa ccaatggata
     9901 gtgaagaagc agtcttgcaa atgaacatgc tgggacataa cttctttatt tttgaagatg
     9961 cagaaacaaa tggtacaagt atcgtttacc gccgtaaaga tggaaaatac ggactgattg
    10021 aaacagactg atcagcctta cttaaataac aacgaaaact tgcagcagct actgacagct
    10081 gccgcaagtt tttttgagtt tcctcctctt ttagatgaaa tatgaataaa ttatgaagtt
    10141 cttactttaa tacgcttaag atatttcaat tatctataac taatgataaa atgaaaagta
    10201 aagtctacat agtctggata atacacagaa ggaaaaggag attacacaac gcatggccaa
    10261 tttgattcgt tcacttatcg aaaacgataa gaaagaacta aaacgtttag atagcattgc
    10321 aaaaaaagtt gaagcatacg ctgaccaaat ggcagcatta actgatgaac aattacaggc
    10381 aaaaactgct gaattcaagg gcagatacca aaaaggagaa acattagatc aattacttcc
    10441 ggaagctttt gcagtcgtcc gagaagcagc aaaacgtgta ttaggtttat atccatacca
    10501 cgtacaattg atgggtggaa tcgtgcttca cgatggaaat atccctgaaa tgcgtactgg
    10561 tgaaggtaaa accttgaccg caacgatgcc agtatatcta aatgctctga ctggcgaagg
    10621 ggtacacgta gttaccgtca atgaatattt agcaacccgt gactcgacgg aaatgggcga
    10681 actttataat ttcttaggat taacagtggg gttgaatatc aactcaaaat cttcggatga
    10741 aaaacgcgag gcttataatt gtgatatcac ttatagtacg aataatgaat taggatttga
    10801 ctacttgaga gacaatatgg tcgtttaccg ccatcaaatg gtacaacgtc cgctgaatta
    10861 tgccattgtc gatgaagttg actcaatctt gattgatgaa gcgagaacgc cgctgatcat
    10921 ttcagggcaa gcagaaaaat ccacagcttt atatacaaga gcagacaact tcgtgaaacg
    10981 tttgaaagaa gaagaagatt ataaaatcga tgtacaatca aaaacaatca gtttaaccga
    11041 agcagggatc gaaaaagcag aagaaacatt cggtttggat aacttatacg acattgaaaa
    11101 tactgcattg acccatcact tggatcaagc attgagagcc aactatatca tgcttttaga
    11161 tatcgattat gttgtccaag acggaaaagt actgattgtt gaccagttca ctggtcggat
    11221 catggatgga cgccgttatt cagatggact tcaccaagca atcgaagcta aagaaggcgt
    11281 agagatcgaa gacgaaacga aaaccatggc gacgatcact ttccagaact atttccgtat
    11341 gtacaagaaa cttgcgggaa tgactggtac agctaaaaca gaagaagaag aattcagaga
    11401 aatttataac atccaagtat accagattcc gacaaatcgt ccggttatcc gtgatgatcg
    11461 tccagatttg ctttacccaa cattacaaag caagttccac gctgtcgtgc aagatatcaa
    11521 agatcgctac cgcaaaggtc aacctgtgtt agtcggaact gttgcggttg aaacatctga
    11581 gttattatca gatatgctga atcaagaacg tattcctcat gaagtgctga atgcgaaaaa
    11641 tcactttaaa gaagcagaga tcatcatgaa tgctggtcaa aaaggtgctg tgacgattgc
    11701 taccaacatg gctggtcggg gaacagatat caagttagga cttggggtaa gagaacttgg
    11761 tggtctagca gttatcggga cagaacgaca tgaatctcgt cgtatcgata accagcttcg
    11821 aggacgtgca ggacgtcaag gagaccctgg tatgtcacag ttctacttgt cattggaaga
    11881 tgatttgatg aaacgattcg gttcagaacg aatcaaatct ttcttagatc ggatgaagat
    11941 cggtgaggaa gatgctgtta tccaaagcaa gatgctgacg aaacaagtag aatctgcaca
    12001 aaaacgtgta gaaggaaata actatgacac acgtaaaaac gtcttacaat acgatgatgt
    12061 gatgcgtgaa caacgtgaag taatctataa acagcgacaa gaagtaatca tggaagaaaa
    12121 aagcttatcc aagccactaa tgaacatggt caaacggaca atcagtcgtg tagtagatgc
    12181 gcatacacaa ttagagaaag aaaattggaa tttggaaagt atcatcgatt ttgccggcag
    12241 tactcttgtc catgaagata gtattactct tgcagatatc gaaggaaaaa cagctcagga
    12301 gatcaaagag tatctaaacg aacgagcaca agaagtattt aataccaaag cggctcaact
    12361 aaatggtcca gagcaactgt tggaatttga aaaagtcgtg atcttgcgtg ttgtggactc
    12421 taaatggaca gaccatattg atgcaatgga tcaattacgt cagtcaatcg gcttacgtgc
    12481 ttatggacag aacaatccat tagtcgaata tcaaacagaa ggctataaga tgtttgaaga
    12541 tatggtaggc gccatcgagt atgaagtcac tcgaatcttt atgaaagctg agatccgtca
    12601 aaacgtacag cgtgaacagg tttctcaagg aacagcttct cactcagaag acggagatgc
    12661 caaagaaaat agtaatacta gcgcgaaaaa acagccaatc catgtgaaca aggtcggaag
    12721 aaatgatcct tgtccttgtg gaagcgggaa aaaatataag aactgtcatg gaaaaaatgc
    12781 aaactaattt ctgacagcag gattggtgag acaaattctt tttttaagaa ttcgtctcac
    12841 cttctttctg ttatttgctg attctgttag actagatata atgaaaaaag tatagtgaaa
    12901 gaaggaaaaa acatggaaat atccgaaatt cgaaatctcc tgacagaaat gcaggaaaag
    12961 gtcacaagct tcaggaggtc tctttgactt agaccagctg gaagaagaca ttgcggaagc
    13021 agaagcaaaa atggctgaac ctggtttttg ggatgatagc gaagctgctc aaaaagtgat
    13081 cagtgaaaac aatgcaaata aagaaactta tgatcaattc cattctcttg ctgaagaact
    13141 ggaagaaatc gaattgatgg tggagatgtt gcaggaagaa cctgatgcag ccatgcaaga
    13201 agaagcagaa acacgtatca atgcgctaga tgaaaaaatg aagacatatg aattatctat
    13261 gttgttagat ggtccttatg atcgaaacaa cgccatcgtt gaattgcatc caggggctgg
    13321 cggaacggag tcccaagatt ggggcagtat gcttttacgt atgtatacac gctgggcaga
    13381 gcagcatggg tatcaagtag agacactaga ttatcaagca ggtgatgaag caggaatcaa
    13441 gagtgtgacc ctactgatca aaggacacaa cgcatttggt tatctgaaat cagaaaaagg
    13501 tgttcatcgc cttgtacgta tctcgccttt tgactcagcg aaacgacgtc atacttcttt
    13561 ttgttcggta gatgtgatgc cagagcttga tgaaacgatc gatatagaaa tcaatccaga
    13621 tgatttgaaa atcgatacgt accgagcaag tggtgcaggt ggtcagcaca tcaataaaac
    13681 agaatctgct gtacggatca ctcacttgcc tacaggaaca gtagtagcta gtcaggcaca
    13741 acgttcacaa ttgaaaaacc gtgagcaagc gatggggatg ttaaaagcta agctttatca
    13801 attagaagtg gaaaagaaag aacaagaagc agctgcactt cgaggagaac aaaaagaaat
    13861 cggctggggt tcacagatcc gttcttatgt tttccatcca tattctatgg taaaagacca
    13921 tcggacaaac gtagagacag gaaatgtcca agcagttatg gacggtgacc ttgatttatt
    13981 tattgacggc tatttaaaaa tgcatctaca ataagaaccc attgttaaat tgaaataaaa
    14041 ttgtaagatt ttgcaagcat gttgaaacat tgccatgcta taatagctaa agactgaaaa
    14101 agatatggag agaacgccat gattgaaatg aaggatgtaa tgaagaagta ctcaaatggt
    14161 acgaccgcta tccgcaatct ctcaattgtc atcgaacaag gagagtttgt ctatgtggtt
    14221 ggtccgtctg gagccggtaa atctacattc atcaaattga tgtatcgaga agaaaaagct
    14281 tcaaaaggaa ctttgaacgt cgcaggtcat gatctaatag caatcaaaaa ccgcgaagtt
    14341 ccttatctac gcagagaaat cggcgtggtg ttccaagact ataaattatt accaagaaaa
    14401 acagtatatg aaaatgttgc gtacgctatg caagttatcg gcagaaaacc tcgggatatc
    14461 aaaaaacgag taatggaagt gctggacctt gttggtttga aacacaaagt tcgagtcttt
    14521 cctagcgaat tatccggtgg ggaacagcaa cgtgtctcta ttgctcgggc aatagtgaat
    14581 acgcctaaag tacttatcgc ggatgaaccg acaggaaatc tggatccaga aaactcatgg
    14641 gaaatcatga aattattaga tcggatcaat gcccaaggaa ctactgtcgt gatggctaca
    14701 cataacagta cgatcgtaaa tacgattcgg caccgagtaa ttgctatcga aaacggccgc
    14761 attattcgag atcaagcgga aggggaatat ggatacgatg attagaacct ttttccgcca
    14821 tttattagaa agtatcaaga gtttgaaacg taacggctgg atgacagttg cttcagtcag
    14881 tgcggtaacg atcacattga ctttagtcgg tgtattcatg gcagttatca tgaacgcaac
    14941 taaattagct caagatatag aaggaaacgt tgatgtctct gtattcgtag atatcggtac
    15001 aaaagacgaa gagatgaaaa agctagaaaa agaattgaat gacttagatc atgttaaaaa
    15061 agttgaattt tcaagcaaag aacaggaatt gaaaaaaatc caaaacgaaa tgggtgattc
    15121 ctggaaattg tttgaaggtg acaataaccc gttatatgat gtgtatgtag taagtgctac
    15181 tgatccttct tatacaaaac aagtagcaga agaagcagca gatttgaaga atgtttctcg
    15241 ttctgattac ggtggagctt cctcagatcg gattttccaa atcgctggtg cagttcggac
    15301 atggggatta gttgcagcgg cattgctgct gttcgtagcg atgtttctca tttcgaacac
    15361 gattcggatc acgattttgt ctagacagcg tgaaattcaa atcatgcgtt tagtcggtgc
    15421 aaaaaatgga tatattcgct ggccgttttt ccttgaaggt ggctggatcg gtctgatcgg
    15481 tgcgattctt ccgattttga tcatcacatt tggttatgca tggtttttcc aattgatcaa
    15541 tccatcatta ttacgttccc attattcatt gattcatcca caaaatatcg tttggaaaat
    15601 caatctttta atggtcggca ttggtgtgat cattggttca cttggctcga tcatttctat
    15661 gagacgtttc ttgaaattct aataccacaa tataaataaa atgagaaagt tggacagttt
    15721 cgttccagct ttcttttttt attggctagg agaatagaag gaagcggctt ttttcccttt
    15781 actttaaaaa acaacttggg tattcttaag ttggtagaag aagaggtgaa gccgtgaaaa
    15841 ttatcgttga caattttttt acgatccttt tgattatgaa tattttgctt tcctttatca
    15901 tcgtttttcg agaaagaaag gaaactgctc aaacatgggc atgggtgctc gttttgatgt
    15961 tcattccagt tgtaggattt attttatata tttttttagg aagagggatt tccaaagaga
    16021 aaatctttga tttgaagatc caagggaaaa tcggtaagaa cctggaaatt gaagaagaca
    16081 aacaggcatt gatgcgaggg ctttatcctc atccgcctac tggacaagta gatgtgaaac
    16141 aattgatcta tatgctcacg gtatttgaaa gtacgctcta tacgactaaa aatgaaatca
    16201 ctttatttac agatggtcgt gaaaaattcg atgcgctgat tgaagatatc aagcaggcag
    16261 aagaccatat ccacttccag tattatattt atcgcagtga tgcattaggt gaagaagttc
    16321 gagatgcatt gacagaggcg gcaagacgag gggtaaaagt cagagtcctt cttgatgcat
    16381 ggggttccac acaagtttct tccagctttt ttcagaattt gaaaaaagca ggcggagaag
    16441 tcgcattttt ctttcctcta tttgttccgt atattaatcc tcggatcaat tatcgcaatc
    16501 atcgtaaaat cgtagttatt gatgggaaaa tcggatatac aggtgggttc aatgttggaa
    16561 atgaatatct aggattggta aagaaatttg gttattggcg agacaatcat ttgcgtattt
    16621 acggagaagc ggtgtatacc ttgcaaaacc gttttttgat ggactggaat tctcagcata
    16681 caaaagaagt aggctattct cccaaatttt ttccgtccat tcactctact ggtgatatag
    16741 ctgttcaaat cgtgacaagc ggaccagata ccgaacatga acaaatcaaa atgacttatt
    16801 tgaaaatgat ttcgttagcc aaacgggaga tattgatcca aacgccttat tacataccgg
    16861 atggatcgat tcatgaagca ctgaagttgg ctcttctttc aggcgtaaaa gttcatatcc
    16921 aaatacctaa caaaccagat catcttctcg tttactgggc aacgtattct ttcgctgcag
    16981 agctaatcga gtatggagca aggatcgaaa catatgagaa tggatttatt catgcaaaga
    17041 cgatgattat cgatggtggc attgtttcag ttggctcagc aaatatcgat gttcgttcat
    17101 ttcgcttgga ctttgaggtc aatacactgg tttatgatga acgaatggct tcacgtgtaa
    17161 gaaaagcttt ttttgaagac tcgaaaattt ctacgcatct cacaaaagaa atgtatgaaa
    17221 accgaggaat aatcatcaag atgaaagaag gattagcaag attgatttcg ccgctccttt
    17281 aaaacataaa aaggacatga gaaccatcaa cagatggaga tctcgtgtcc ttttctaacg
    17341 gggccatttc tgagagtacg tcagaaatgg agaaagcgtc tcgcatgagc gaaattaact
    17401 ttggggtatc tcttgttttt tggggaaagc aagaaataag ctaatatatg ctattaaaag
    17461 agacacattt caaagccagt atagcataga aacttttaat gagatagttt tttttacaat
    17521 tatgagaatt tattttgtta tttaatgatt ttgattcgtt ttcatcaagt aatgaaaatg
    17581 ataaaataaa catactttag gattaaagga gatttctaat gaaaaaactt aaattattct
    17641 taccaataat aggattagct attcttttat caggctgttc aaagtggatt gatcgaggag
    17701 aatccattac ggctgttggc tcttctgctt tacagccttt agtagaaaca gttgctgaaa
    17761 cttaccagac agaaaatcct ggaaaattca tcaatgtaca agggggcgga agcggaactg
    17821 gtttgtctca agtacagtca ggagcagtcg acatcggaaa ctctgatttg tttgcggaag
    17881 aaaaatcggg gatcgatgcc tcagcattag tcgatcatcg agtagcagtt gttgggatca
    17941 ctcctattgt gaacaaggat attggcgtaa aagacatcag tatggaaaac ctgaaaaaac
    18001 tatttacagg cgagatcaaa aactggagtg aagtcggtgg aaaagatcag ccagtagtta
    18061 tattgaaccg cgcttcagga agcggaaccc gtagcacgtt tgaaaaatgg gtattggacg
    18121 gagaaacagc tgttcaggca caagaacaag attcaagcgg aatggtgcgc cagatcgttg
    18181 ccgacacacc cggtgcaatc agctatgttg ctttttctta tgtttccgat gatgtagata
    18241 cgttgaatgt taacggtgta gaaccgacag atgaaaatgt gacaacgaac aaatggacga
    18301 tttgggcata tgagcatatg tacacaagag atcatccaaa aaaactgaca aaagaatttt
    18361 tagactatat cttatctgat gaagtacaag ataacatcgt tggagaacta ggttatatcc
    18421 ctgtttctca tatgaaagtc gaacgtgatt ggcaaggaaa tatcgttaaa gagtaatctt
    18481 tacacaaaat ttacaaactt agctaaactt ttacatgtta ttaaaaccaa attgatgttc
    18541 aatttgtaca ctgagtgagt atgttaaacc tgattaaggg ggagtcatct gtggaagatg
    18601 tgaaaaaagt attattaaca aaatcaaaac gttcaaaaat ggaacagcgt ggaaaattca
    18661 tcagtttttt atgtatcgcg ctgatcgtgt tggttgtatt atctattttt tattttgtag
    18721 ctagtaaagg attggccacc ttttttactg ataagatcaa tgtatttgat tttctgtttg
    18781 gtacagattg gaatccaagc caaatcggag caaatgggaa accaatggta ggggcattgc
    18841 ctatgatcac aggttcgttt attgtgacct ttttatctgc tatcgttgcc acgccatttg
    18901 ccattggtgc agcagtattc atgacggaga tctctcctaa aaacggaacg aagatcttac
    18961 agccggtcat cgagctgctt gtaggtattc cttctgtcgt ttatggtttt atcggtttat
    19021 cagttatcgt gccttttgtc agaagtattt ttggcgggac tgggtttggt atcttagctg
    19081 gtacatttgt gttgttcgtt atgatcttgc cgactatcac aacgatgact gttgatgcat
    19141 taaaggcagt gccacggcac tatcgggaag cttcattagc gcttggtgcc acaagatggc
    19201 aaacaatcta caaagtcgtg ctacgagcag ccgtgcccgg gattttaaca gcagtcgttt
    19261 ttggtatggc tcgtgcgttt ggtgaagcct tagctatcca aatggtcatc ggtaatgcag
    19321 cattgatgcc aacaggtctt actactcctg cttctacatt gacgtccatc ttaacaatgg
    19381 gaatcggaaa tacaatcatg ggaacagttg aaaataatgt gttatggtca ttagcgctga
    19441 tcttgctatt gatgtcatta ttctttaata tcgtgatccg tatgattggg aagaaaggag
    19501 agctgaaata atgaacgcaa aacgctcaga taaaattgct acaggtgttt tatatatagt
    19561 ttcggggatc atcgtattga ttttagcagc tttactactt tatatcttag ttcggggaat
    19621 accgcacatt tcatggtcct tcttgaccga accttccaaa gcctaccaag aaggcggtgg
    19681 aatcgggatc cagctattta actcgattta tttgcttttg atcacgatga tcatcagttt
    19741 tcctatttct ttaggtgcgg gtatctatct ttcagaatat gctggaaaaa actggctaac
    19801 agatgtgatt cgcacgtcga ttgaaatctt gagctcgttg ccttctgtcg ttgtcggttt
    19861 attcggtttc ttggttttcg ttattcaatt ccagtatggt ttctcgatta tttctggtgc
    19921 attggctttg actgtattca acttgcctct tttgactaga acagttgagg agtctttaca
    19981 agcggtccat tacacacaac gagaagcagg attggcctta ggtttgtcac gctgggaaac
    20041 agtgataaaa gtggtggttc cagaagcgac accagggatt ttgactggtg tgatcctaag
    20101 ttctggaaga atttttggtg aagcagctgc attgatctat acggctggac aaagtgcacc
    20161 tgcgttagat tttacgaact ggaatccatt aagtgtttca agcccgatca gcattttccg
    20221 tcaagctgaa acattagctg tccatatttg gaagatcaat acagaaggca cgatgcctga
    20281 tggtgtttct gtttcggctg gcgcttctgc cgtgttgatt attgctgttt tactgttcaa
    20341 cttcggcgct cgtgcgattg gcaaacgatt ataccgaaaa atgacttcag cctaaggaga
    20401 agaagcaaaa tgaaaaaata taactggaat gaaacaaatg tcatcaccat gccaaaagag
    20461 aaagaagtag cactatatac ggatgatcta catgtctggt atggcgacaa tgaagcaatc
    20521 aaaggagtgg atctggaatt tgaaaaaaat aagatcactg cactgattgg tccttccggc
    20581 tgcggaaaat ctacgtatct tcgttcgttg aatcgaatga atgatgggat cgctaatacg
    20641 aaaatcactg ggaaaatcat gtatcaaggc gtagatatta atgcgcctca agtggatgtt
    20701 tatgagatgc gcaaacggat tggcatggtt tttcaacgtc ctaatccgtt cagcaagtcg
    20761 atttatgaca atattacatt tgctttgaaa cagcacggcg aaaaaaacaa aaagaaatta
    20821 gatgaaatcg ttgaaacaag cttgaaacaa gctgccttgt gggaccaagt aaaagacagc
    20881 ttggacaaaa gtgccttggc tttatctggc gggcaacagc aacgtttatg tattgctcgt
    20941 gcgatcgcga tgaaacctga tatcttgctg ctagacgagc cggcaagtgc tttggaccct
    21001 atttcgacag gaacggttga agaaacactt gtaaacttga aagaagacta tacgatcatc
    21061 atcgtgacgc ataacatgca acaagcagct cgtatcagcg actatactgc ctttttctat
    21121 ttaggaaaag taatggaata tgacaaaact aacaagatat ttaccagacc aaaaattcag
    21181 gcaaccgaag attatgtgtc cggtcatttt ggttaagacg gaggcctcaa catgacaaaa
    21241 gagattattt catctaaaga tcttcatctg tattatggaa agaaagaagc actaaaaggg
    21301 atcgatctaa gcttcaatca aggggaaatc actgcgatga tcggtccttc tggttgcgga
    21361 aaatccactt atctgcgttc tttgaaccgg atgaatgacc tgattccgaa tgtaacgatc
    21421 accggaagtg ttttatataa agacaaagac atctatggtc caaaaacaga tgttgttgaa
    21481 ctaagaaaag aaatcggcat ggtattccag cagccaaacc catttccttt ttctatctat
    21541 gaaaatgtca tctatggatt gaaattaaaa ggggaaaaag ataaaaaagt ccttgatcaa
    21601 gtagttgaag aaagcctgaa ggcagcgtct gtttgggatg atgtgaaaga caaattgcat
    21661 aaaagtgctt tatctttatc cggtgggcag cagcagcgtg tatgtatcgc acgtgttttg
    21721 gcagttaatc cggaaatcat cttattggat gaaccaacaa gtgcgcttga tcctgtttct
    21781 actgggaaaa tcgaaagtat gctgttagaa ttaagagagc ggtatacgat gatcatcgtg
    21841 acccataata tgtctcaagc ttcacgtatt tcagataaga cggcattctt tttagatggt
    21901 cacttgatcg aatacaatga tacgaagaag atattcatga atccagaaaa acaagagaca
    21961 gaagattata tttcaggtcg atttggataa ggaggaaacg gaatgctacg tacacaattt
    22021 gaagaagaat tgctgaatct ccataatcag ttctacgaaa tggggatgat ggtgagcagc
    22081 gccgtgcaca agtcagttcg tgcatacatc aaacacgata aaatcttagc ccaagaagtt
    22141 atcgaaaacg atataaatat caataacatg gaaacacgct tggagaagaa aagttttgaa
    22201 atgatcgcat tgcaacagcc agttacaact gatttgcgta tgatcattac ggtcatgaaa
    22261 gctagctcgg atttagaacg tatggccgat catgcggtgt ctgttgctaa atccacgatt
    22321 cgcgtaaaag ggcagacgag aataccggaa atcgaaaaag agatctccga tatgtccgat
    22381 tatgtgaaaa aaatggtgga caacgtccta gttgcttatg tcaaaacaga cgaaaaagac
    22441 gcacgtacga tcgccaatat ggatcaaaga gtcaatgact atttcaatcg aatctataat
    22501 gcaacaatca aaaatatgca ggaaaatcct gagacagtca tcagtggaac agactacttg
    22561 aatgttgcca gttatctaga acggatcgga gactatgtga caaacatctg tgaatggatc
    22621 gtctacttgg ctacagggaa aatcactgag ttaaatacga accacaatga gattttctaa
    22681 actgaagctg tgattatgcc gtttgtttag gaaaagaggt tgtgaaatca gcggttgtga
    22741 aaaagctgtt ctgcatcaag taataagaac agtcaaacaa aaaatagctc ctcatatttt
    22801 tcgtttggct ggacttatta ccgcagatgc aagcttttga acaccgttta ttcgggaaag
    22861 ggtttgtgac aaaacatgtc acaaaccctt ttcatcattt catagaaagg ataaagaatg
    22921 caaaaaaaaa ttagcatcat cactatattt tttatttgtg tgcttacttc atgggttatt
    22981 cagcatcaag ccgctttata tgaagtacct gtcatcgaga tagaaaaagt acgaataaaa
    23041 gaggatcatc aattgattac aggaaaactg atgaacacgg atcaaaaagg agaatcgatt
    23101 tatttatcgg ttccttatca aaaaaatcaa atagaaacag caaatataaa agcgagacaa
    23161 atgtatctag tccaaatgca tggagatgaa tggcagctag tagcaaaaaa aaatgatggc
    23221 tggcttttct tcttcacaag tatcttcatt ggcgccatgt tgcttattgg tggaaaacag
    23281 ggtctatttg ctttaggaag tctcatcatc aatatcgttt tacttttact tttgttgctc
    23341 atctttacta aaacagaagg gatttctcta ttaaatatat ctatcctgtt cgtcgttata
    23401 gggatgatta ttagcatatt ggctttagat ggatggaata gaagcagtat aatcaaaatt
    23461 tcagctgcag ttacgagtgt ttttttagca ttttttattt gtcttttgac aatgaatcat
    23521 tggaaagacc aaggactgcg ctatgaggaa ctgaattatc tgacacgacc gtatcgttct
    23581 gtttttcttt ctagcgtact gattggaaca gctggaggaa cactcgatac cgttatcaca
    23641 gtcattgcga cattagaaga attgactaag cgacaaccag aaataacagc gaaacagtta
    23701 tggctttcag gaaggcaagt gggtcgagat gtgattggct cgatgaccaa tatccttttg
    23761 ttcgtctata tcagtgggtc agttccatcg cttcttttat atttaggaaa tcaatggtcg
    23821 ttcaaagaaa cgatagaaca gcatttatca ttggaatttt tacgcgtcat tgctggcagc
    23881 ttaggaatag tattatcgat ccctatctcg gtcctctttt ttctgactgt aaggaggctg
    23941 aaacgatgaa tgtacttatt atacttgttg ggattttagc aatcagcgtg ctacttattg
    24001 gcggtacgca aggtatgtat attcttttag gcttattcat caatttaggg atctttttcc
    24061 tgttgttatt cggttatcat cagaagtggc cgatactggc attgtcggtc ataggatttt
    24121 tattgattgc tgtggttatc ttatttttta tcaacggtta taatctaaaa atgcgtgcag
    24181 cttttgtgag tatactgatc tttttatttt gtttcctact attgcttcct atcactgatt
    24241 ttttagcaat ccaaggtttt acatcggtag aactagaaga attatctggc ttagataaga
    24301 ctttagcgat tgattttaga ttacttacga gatcgttgct tctgattagt cttagtggtg
    24361 ctgttttaga tgcgagtgta gcaatttcta gtgggacatt cgaagtatat caggcaaatc
    24421 cgcaattatc tttttaccaa ttgcgccatt ctagtttcgc tattgctaaa aaaatattgg
    24481 cgtcaacagt aatgacactt ctttttgcat tcatgggaag ttctttagcg ttgatcctct
    24541 ggtttattga tttagacatt ccttttcagc aagtgatcaa tgaaaaatca tttgttctag
    24601 aatatacgat ggctattctt accacattgt ccgcactact tgttcttcct ttaacctgcg
    24661 tgactacagc atatctcttt acaaaaaaga aagaacaact caagatggag taaaagttac
    24721 aacttaagtc ctatgacatt tttactgaat cagtgcataa tatggatgta aggaaaagct
    24781 tgcaaacaat tttgcttaag gaggcaattt ccatgaaaga aagagaacgt attttagatt
    24841 tagtgaaaaa aggaatcctt tcgactgaag aaggcttaga tttattagaa agcatggcaa
    24901 ctgaaaaaga cgaaaagcaa atcaaaaaag aagcagacaa ggtaactgct agtcataaag
    24961 aaaaagatca ggcaagtcaa ttgatcgata aacttgaaaa cggcgaagaa gaaatttctg
    25021 agccagttga tccaaaggaa agagaaagac aagatcaaga aaacttagaa aagatcttag
    25081 atgaactagc aactgaagcg aataaaactt cggcgcgtct agatgaagta aatgctcaat
    25141 tcgctgacaa taaggcagca cgcaatgaga aacaggaagc attgatgcag ctgaatacaa
    25201 aagaagaatt aggcgagttg acagaagaag aattagcaca gcgtcagacg ttagaagcag
    25261 aaatcaaaga attagaagct agtggcgata cactgttaga agaacaattg aaattagaag
    25321 cagaattaaa agatatccgt aagaatcaat ggtctgagaa aaaagaaacg tttactgata
    25381 agtttgaatt gccagatgat tggaaagatc aagcaacaga tacactgaat caagtaggcg
    25441 aaaaaatgtc agaagctgga tcacagttag gcaaattctt gaagaaaaca ttccaaactg
    25501 tttcagaaac agtgaatgac aacatggaat ggaaagatgt cagcttacgt gtccctggga
    25561 ttgcgacaac gaaatttgag catgaatttt actatgaagc tcctgcagca agtatccttg
    25621 atatcaaggc agcaaacgga aacgtgacgt taaaaacgtg ggacagcaac gatgtgaaag
    25681 ttgaagctaa gatcaaactt tacggaaaaa tgggtgctga accatttgaa gcattctctg
    25741 aacggagcca gattgaggtt aatgaagatc atatctcctt ccaaattcca aataaacgtg
    25801 tgcgtgcaga ccttgttttc tacttaccta aacgagtata cgaccacgca gctattaaac
    25861 ttctaaatgg caacatcatg attgaaacat tggaagctaa agatatttat acaaaatcta
    25921 cgaatggtaa catcatcgtg gaccaattaa ctgcaacgat gctggaagta gaaggtgtaa
    25981 acggcaatat cgatattcga aacgggaaca tcttagattc tattatcgaa acagtaaatg
    26041 gtacagtgac atttggtgcg acagcagaaa acctttctgt gtctttggta aatggtgatg
    26101 tacgtcttac gattaaagaa gataatttga aaaaagtaga agcaagttca gtgaacggaa
    26161 atgtcaaagt cgctttacca gatggcatcg gtttggaagg acatgctaaa acaagtcttg
    26221 gaagtatcaa cagccgtctg tccaattacg aagtagttcg tgagaaaaaa gaacggacaa
    26281 accaaatgtt gcaattccgt cgtgtttcag atggtgaaat cgcgcaagtg caactttcaa
    26341 cgacaacagg aagtatctat ttaaaagata cagataaata aagaggttgt gaaagagatg
    26401 ttcagccttg agcaataaga agcgattttg taaaatagct tcccctattt tacaaaattg
    26461 tgccttattg ccgatagtct atctcttgaa caccgtttac caagagatta tgaacctgcc
    26521 aattatcgcc gagtcacaag gaataatttc agaaaaagct cgtcacgttt tatgaatatg
    26581 gtaatttgtg accgagaatt ttgcagaaag acaccgatta agaagaaggt tgtcacaacg
    26641 attttcttca tttaaaatag tagaacagag gtgagacatg atgaaaaaaa agttgacaaa
    26701 atctaataaa aatgttgttt tgacagggac tttagcagga ataggagaat acatcgggat
    26761 tgatccgact gttatccgtg tgctttatgt attcctgagc ttagttgctt ttggaagtcc
    26821 aattatttta tacattttat tagctttgat tatcccatct gcgcgttctg cacgaacaaa
    26881 ctatggacat aacaatgcat attatgaaaa aaacaattat cgtgaacaaa ctcgtgaaca
    26941 aacaaaaaaa cgcaaagaag cggaaaaaat cgatgatgac gaatggagtg acttttaatg
    27001 tcgtactttc aacgtatttt agttaatacg ttaacattca tatcattggc tgttcttttt
    27061 cctgcgatgg tccatgtgag cagtatttgg acggccgttc ttgccagctt cgtattgtct
    27121 gtgttgaata tgtttgtcaa accgattttg acgatactgt ccctgccctt tacattagtc
    27181 acattgggat tgtttacgtt tgttatcaat gcagcgattc ttaaaatgac ctcctttttt
    27241 gtgggagcag aacattttag tttttcttca ttcggtgcag cgttgttagt agctatcttg
    27301 atgtcgcttg tcaatgtaat tgtcagcgaa cataacagta gaaaataaaa gaaagctgtg
    27361 ccgaactatc ggcgcagttt ttttatttag aatcaggaat gcgttttcta ttacattggt
    27421 aattaaataa aaacgttttt tttaattggt agtacttttg gctagacaat gataaaatga
    27481 tagagaacac tctaatagaa atgaggtagc atgaatgtca gaagttgtaa aagttagcca
    27541 attagtgaaa aaattatctt tggaaatcgt gacaggcgac gagaaaagct tagaccgtgt
    27601 catcgtaact ggggacatct cacgcccagg actagagttg actggttatt ttaattatta
    27661 ttcccataat cgtttacagc tatttggcag taaagaaatc agttttgcgg aacggatgat
    27721 cccagaagag cgtttgatca tcatgagaag attatgtagt gaagatatgc ccgcatttat
    27781 tatttcaaga ggattaccag ctccagaaga aatgatccag gcagcaaata aaaatgggat
    27841 agctgtactg cgttctccca tctcaacttc tcgtttatta ggagaattat ccagttattt
    27901 agatggtcgc cttgcccctc gaacaagtgt ccacggtgtt ttagtggatg tttacggatt
    27961 aggtgtactg attcaaggtg acagtgggat aggaaaaagt gaaacagcgt tggagttgat
    28021 caaacgcggc catcgattga tcgcagacga tcgagtagat gtttatcagc aagatgaatt
    28081 aacggtgatc ggagaaccgc ctaaaatcct ggaacatctg attgaaatcc gaggaatcgg
    28141 gatcattgat gtaatgaatc tttttggtgc gagtgcggta cgtggctcta tgcaagtcca
    28201 gttggctgtt tatctggaag catgggcaaa agataagaaa tacgaccgtc tgggctctga
    28261 agacacgacc gttgaaatcg cggaagtggg cattccacaa ataaaaatcc ctgtcaaaac
    28321 aggacgaaac gttgcaatca tcattgaagt agccgcgatg aatttccgtg cacgtacaat
    28381 gggctttgac gcaacgaaaa catttgaaga aagattaagt cgcttgattg aagaaaactc
    28441 aggcaacgac tagcaaggag tgacaatatg ttagcacaaa tcaatcgagt tgcttttgag
    28501 cttgtaggga ttcctatcta ctggtatgca ttgatcatcg tatcaggtat cattatcgct
    28561 atgtggctta gcagcagaga ggctgttcgg gtaggattaa aagcagatga tgtgacagat
    28621 tttatgttgt ggggattgcc tatctccatt attggcgctc gcttatatta tgttttattt
    28681 gatcttcccc agtatatagc tgatccaatc caaatattca atatccgttc aggaggctta
    28741 gctatttatg gcggactgat tgcaggcgcg atcacgctgt atttttttac taaatatcat
    28801 tttatttctt tgtggacttt tttagatatc gctgcaccaa gtgtattatt agcacaggca
    28861 atcggtcgtt ggggaaattt catgaaccac gaagcatatg gaccagacac gacgcgaagc
    28921 ttcttagaaa gtctgcattt accgcaattc atcattgata atatgtatat cgaagggatc
    28981 tatcgtcaac caacatttct ttatgaatca ctttggagtt tgattggatt tattttgctt
    29041 ttgtttttac gaaagaaacc acaccttttg aaaaaaggcg aagtcctttt atgttatcta
    29101 atgtggtata gtttcgggcg tttctttatt gaaggattac gtacagacag tctttacttt
    29161 ttaggtgtga tccgtatttc tcaattatta tctgctgtgt tatttgtcgg tacattgatt
    29221 ctatttattt ggcgcagaaa aaaaggaaat ttaccggatt atgaccgctc attaggaaaa
    29281 aatcaacaaa ttatctgatt tttagagcgt taaaaatgaa aaaaatttca ggagtggtaa
    29341 aatgaattat agagtagcgg ttttaggacc aggctcttgg ggtactgctt tggcacaagt
    29401 cctcgccgaa aacggacatg acgttcggat ttggggacat cgtgcttcac aagtagaaga
    29461 aatcaacacc caacacacga atcaacgtta tttaccagat cattatctac ccgattccat
    29521 ccaagcattc accaatatgg aagatgcagt aaaagacgca gatgcggtgc tattcgtcat
    29581 tccaacgaaa gcaatacgtt ctgttgcaaa agaactagtg cctaaattga atacaaagcc
    29641 agtgatcatc catgcaagta aaggattaga acagggaaca cataaaagga tctctgacat
    29701 cttgttagag gaaatcccag cagaaaaaag aaaagctgtt gttgttcttt ctggaccaag
    29761 ccatgcagaa gaagtagcaa aacatgacat cactacgatc acagctgcaa gtacagatgc
    29821 aaaagcagca aaatatgtac aagagctgtt catgaataat tattttcgga tctataccaa
    29881 tcctgatgtg atcggtgtag agatgggggc agctttgaaa aatattattg ctattggtgc
    29941 tggcgctatt cacggcttag ggtttggcga taatgcaaag gcagcaatca tgacgcgcgg
    30001 attagctgag atcagccgtt taggtgtagc aatgggtgcc aacccgctga cctttatcgg
    30061 attaagcgga ataggcgatc tagtcgttac ttgcacaagt gttcattcta ggaactggcg
    30121 cgcaggcaac ttgttaggac aagggcagcc cctagaagag gtgctagcca atatgggaat
    30181 ggtcgttgaa ggtgtgaata ctacccaagc agcgatggaa ctagcccaaa tgatggaaat
    30241 cgaaatgccc atcactcaaa caatctatga agtgctgtat gaacaaaaag aaatcaaaac
    30301 agccgcaaaa gaaatcatgt tacgtgatgg aaaaaaagaa aatgaattct cattaacaat
    30361 tttttgaagg agcgaatgta tatgaaagtt aaaaaagcag ttattccagc agcaggatta
    30421 ggaacaagat ttttaccagc aacaaaagct atggcaaagg aaatgttgcc aattgttgat
    30481 aaaccaacaa tccagttcat cgttgaagaa gcgttgaaat caggtatcga agacatcttg
    30541 atcgttacag gaaaagctaa acgaccaatc gaagatcact ttgattcaaa tattgaatta
    30601 gaaacaaacc taagtgaaaa aggaaagacc gaattattga aattagtaga agaaacgaca
    30661 gatgtcaact tgcatttcat ccgtcaatct catccaaagg gtttaggaca tgccgttctt
    30721 caagcaagag cctttattgg aaatgaacca tttgtcgtta tgctaggcga tgatataatg
    30781 gaagacgaag taccattgac acagcaatta atcgatgatt acgaacgtac tcatgcttct
    30841 acgatcgccg ttatgcaagt tcctcatgat gaaacttcaa aatacggaat tatcaatcca
    30901 ggagaagtat tggaagatgg gttatacaat gtcaaaaact ttgttgaaaa accagatcca
    30961 agcaaagcac caagtgattt agctattatt ggacgttact tattgactcc agaaattttt
    31021 gatgtattgt ccgagcaaca accaggagcc ggaaatgaaa tccaactaac tgacgcaatc
    31081 gatacattga ataaaacaca acgcgtattt gcccgtaaat tcacaggtaa acgttacgat
    31141 gtcggtgaca aatttggttt tatgaaaaca agtattgaat atggtctaac acatccagaa
    31201 gtaggtgcac ctttacgtga gtacatcctg tctttaggta aaacattaga agcagaagga
    31261 agcaagatcg atcataatcc aaaaggaata acagaaatca aagaagaaaa gaaaaaataa
    31321 cccttttttc taacgagctt cagctgctaa ttgaataaaa agtagttgaa gctcgttttt
    31381 atttgtttaa aaaacacgaa aatgctatcc ttatagaaaa gagagacaag aagggagttt
    31441 gatcatgtca ggaggagaaa ttgcaggatt gatcgcagca atcgcctttg cgatacttgt
    31501 cgtttttatc gttcgtgtgt tgttgcaagt ttctaaaact ttagaaaaag tagatcagac
    31561 tgtagcagaa gcaaatacga cgatcgaaat cgtcacaaaa gacgtagatc ttttgtctag
    31621 acaagtagaa ggcttactgg tcaaaagtaa tgaactgctc ttggatatca atggaaaagt
    31681 cgcaacgatc gatccattgt tcacagcagt tgctgattta agtgaaagtg tatcagaact
    31741 taatcattct agtaaaaaca tcgcgacgaa agtcggcgga atcggtaaaa cgacagctaa
    31801 agcgacggtt gccggaaaag tcggtgggac agcgatgaaa ttttttaaaa acaaaaaaca
    31861 tactgaaacg acaggaggaa aataaaaatg gctaaaaaag gtggattttt attaggtgca
    31921 gtagtcggag gcacagccgc agcaatcgcc gcgttattgt tagcaccaaa atctggtaaa
    31981 gaacttcggg atgaattagc tgcccaagcg gatgatttga tggatatggc ttcagattac
    32041 acagatatgg cgaaagaaaa atcgactgag ttaacaggta ttgcaaaaga aaaagcgcaa
    32101 gatctttctc aacaagcagg tgatctagca ggtagtgtca aacaaaaagt aagtgaatca
    32161 gcagatgaag caggaagtga atctgacgat atcttgttaa atcttaaaga acaatcagct
    32221 gacttatcta atcgtttcaa aaaaacggca gaagatatga aaaaacctgc agatgaatta
    32281 ggaagtattg ctaaagatac ttcagaagat atcatgattg atgtaaaaga cgctgctggt
    32341 aaagcaggag atactgtcaa tgaaggaatg tcagaagcaa aaccagttgc agatgactca
    32401 aaagaaatga tgaaaatggc aaaagaagat gcgaaagaag ctaaaaaaga aataaaagat
    32461 acaatgacag attcatctac aaatcactaa aatcacaaat ttatagaata aaaaggtggg
    32521 agcggactag ctctcacctt ttttactctt atttttctaa aacaagtaat tcttttggtg
    32581 tagtcgtgaa tggcacacag ccatcgcttg tcacatatac acagtcttcg atacgtaccc
    32641 ctactttttc aggaatatag attcctggtt caagagagaa gcacatccct tcttcgatta
    32701 ctaagtcatt tccttctaca agggaaggga attcgtggac ggttgttccg atcccgtgac
    32761 ctaaacggtg attgaaatat tcgccgtagc catagctgtt gatcacgttt cgtgcgattt
    32821 gatcaagttc acctgctgtc acacctggac ggacggcttc ttgtgcggca agctgtgctt
    32881 caagagtgat gttgtagatt ttttcttgga agtcggttgg tttttgataa gcaattgtac
    32941 gagtagcatc actgcaatag ccattccaaa caacgccaag atcgaataac acaagttcat
    33001 tcggtgaaat cttcgtattt cctggtgtac catgagggct tgcagcattt gctcctgcaa
    33061 ggactaatgt gtcgaaagac atttgtgaaa caccttgttt tttcaattgg tattcaattt
    33121 ctgcaatgat cgcttgttca gtcacgcctt ctttcactgc tttaaagcca atctcaaatg
    33181 caacatcggc ccatttacca gcttcgatca gtttgtcttt ttcctctaga gttttgatca
    33241 gttgtagacg ttggatgatg gaagttagat cagtgtaaga atccgttccc gtcaagatat
    33301 cagagatagc atcgaagcgc tcgacagtca aggcgttctt ttcaatccct acattgccag
    33361 gctgaccata gcgagcacga agttcttttc cgatgatctc ccaagggttt tcgctgtcta
    33421 aatagccacg gacatcatac gcccaactac tgttttgagc atcttcaact tccaaagcag
    33481 gagtgaaaag gaaaggatct tgttcaagag ggataaaaag agctagtaca cgctcatgag
    33541 gatcactttc gtatccggaa aagtaagcga tgtggccagg gtcgctgata taagccaatt
    33601 cgacttggtg ttgtgccatc cattgacgta gttcattgat ttttacgtta ttcatttggc
    33661 aacctacttt ctaaattaat tttgtattca ataattgtac cactgattta ttaaaagacc
    33721 aacgttctaa aaactgaaaa aagtaaaaat tttcatgaaa acagagataa aacggttgca
    33781 attcttgaga ttatttgata ttctatttta gaaatgtaag acgtattttc agaaaacata
    33841 taaaatatga ataggagaac acaaatggaa aagcaaacaa tcactatcta tgatgtagcg
    33901 agagaggcaa atgtttcgat ggctactgtt tcacgtgtcg taaatggcaa tccaaacgtt
    33961 aaaccagcaa caagaaaaaa agtcttggaa gttatcgatc gcttggatta tcgtccaaac
    34021 gcagttgcgc gtggcttggc aagtaagaaa acaacaacag ttggtgtaat catccctgat
    34081 gtcagcaata tgttctttgc ttctttagca cgtggtatcg atgatgtggc aacaatgtac
    34141 aaatacaata ttatcttagc aaattcagat ggcaacgacc aaaaagaagt caatgtattg
    34201 aataacttac tggctaagca agtggacggc gtgatcttca tgggtcacca tatcacagac
    34261 gaaatccgtg gagaattttc acgttcaaaa actcctgttg tattagctgg ctctattgat
    34321 ccagatgaac aagtaggtag cgtaaacatt gattatgtat ccgcaacaaa agatgcagta
    34381 aacaaattgg caaaaagcgg caataaaaaa atcgcttttg tcagtggtgc gttgatcgat
    34441 cccatcaatg gacaaaatcg tctgaaaggc tataaagaag cattaagcga aaataaccta
    34501 ccatatagcg aaggattgat ctttgaagca caatacaact tcaaagatgg tctatctcta
    34561 gtcgatcgga tccataatag cggtgcaaca gctgtctatg tttcagatga tgaattagcc
    34621 atcggtattt tggatggttt attagaccgt ggcgtgaaag taccggaaga attcgaaatc
    34681 atcacaagta acaattcact actgacagaa gtagctcgtc ctcgtttaac aagtatcaca
    34741 caaccattat acgatttagg ggcggtatct atgcgcctat tgacgaaaat gatgaataaa
    34801 gaagaagtcg aagaaaaaac gattatcttg ccttatggaa tcgaagaaaa aggatctaca
    34861 aaataataaa aggacaacca ttcagaggtt gtgtgcctgc cgtttaactc tgcgttacaa
    34921 ggagcaattt caaaaaacag catctcatgt ttgatgaata ttgtgactcg tgattcggag
    34981 ttggcaggag aacaccgttt atttgggaaa aggggttatg acaaaatttt gttataatcc
    35041 tttttttgtg tcttaaaaaa gagagaaagt ggttgaaatt acatttatcg tatataaaac
    35101 aatccgtgta tagatgctgc attttgttca ccaccatcaa aaaaataagg gactgtgaca
    35161 atactattgt cacaatccct tattactgtg tattctatta aatcaatcat ctttctcatc
    35221 tgattcttta gttgcttgat tcgctcttgc ataagctgaa gcggtgttcc agtaatctgt
    35281 atagttttca tcggtaccgc caacgccaaa tttaaaggcg cttttcttcg gtccattttt
    35341 cgcccatagc gattcaactg tttttcctgg tgtttggatg gattttttat tgacagtaac
    35401 ttttccaggt gtttgaccag taaatccaga tacttttttc ttcatcacat cagatgataa
    35461 ttcgaatttc tcatcagtgc caaaaatgtc aggttttgct tggtaagctt gattgatcag
    35521 attggcaaga taattagccg aacgtatcct tgctttgctg tccattccag tattgtcatc
    35581 gtgccctgcc cagctactga tggtaataga cggagtagag acaattagcc atgaatctcg
    35641 gtattcattg gtagaaccag tttttccgac ccaatctgct tttcctagat ttccgtttaa
    35701 gcttgagatg gcatctttga atggtgtagt gatttttgca ttgatcacac tacgcatcat
    35761 gtcattcatg atcgatgccg ttgcttccga atagatccgg acagagttgc tttcgtgttt
    35821 ataaattaca tttcctgcgt tatctgtgat ggaatcgatg atatagcctt cttcatagac
    35881 gccgccgttt gctaaagcct gaaatccgtt ggtctgttga agcgtcgtga catctactgt
    35941 acctaaagga gcagattcaa cgccccaatt gtcatttgcc gggtagttca tctttgccaa
    36001 gtagtgctcg taagcatatt gtttcgatcc accggaattc aacacatctt gatataagtg
    36061 ataagccggg atattgttgg accattctag tgactcacgg acggtttgga aggtgttcga
    36121 tccttcgtta gtagcattga cgattttctc gccagcattt tctccttctt gccaagttgt
    36181 tgcataatct gatacacggg attctgatcc gataagcccc atgtcgattg caggtccata
    36241 aacaagaact ggtttgattg atgagccagc ttgacgttct gtatcgaagg catggttatt
    36301 ttgattctga ctgtaattcc gtccgccaac gaatccgtag atgcggccag ttctgttatc
    36361 catcaataca tttccggttt ctacttgact gccagcacca tcatctaaca tgtatccata
    36421 attttcaacg ccattttgca atgcagcata gacatcttta tcgattgtcg aatggattgt
    36481 atatccttta ttttggatcg tttgctgtgc cttttgataa taagcgtcac tgaccgatga
    36541 atcagacata tcagcgttgt ctttttcagc caattgttgt gcaatgattc ttgttgcttc
    36601 attcatcaca gtataataca agaattctct gtcagtctgt tctgcgattt gttgtggtag
    36661 aaagtctttt gtaaggtcat aggcttttgc ttcttcgtat tgttctttcg taatttggcc
    36721 ttcacgatac atactgaata aaacaaaatc ttttctggca aggccggcag aaagatcttc
    36781 ttttagcgcg cctgtgttcg tgtatggact atacgtgatc gggctttggg gtaatccagc
    36841 gatataagca gcttgcggca gcgtcacatc ttttgcatct acaccaaaga ttccttttgc
    36901 agcttcctgg actccagcaa tgttttgtcc cttattatta cgaccaaatg gtgagacatt
    36961 caaatacgta gcaatgatct catcttttga aaagtatttt tctacttgtg cagaaagaat
    37021 gatctcgttt gctttacgtt tgaatgttgt ttcatctgta aggatctgct gtttgactaa
    37081 ttgctgtgtc aaagttgatc caccagaaga gccaatacca gtagcttcag atactaatgc
    37141 tcgtaaaaca gctttaggaa cgtaaccttg gtgtttatcg aagtattcat cctctgtgct
    37201 gataattgca gttttcaata aaggtgaaat cttatcagat gaaatagtcg tgcgcatcag
    37261 atctgtctgg atttttgata tctctgtatt atctgcataa acaatctttg acgtttctgt
    37321 aatgtttcct agttctgtct gcagtgcttt tttagtcggc aattgtgtgt cttcgacgag
    37381 ataggcaaaa tagccagcgc ctattccaat acctagagct gcgaacatca aaagaagaac
    37441 agtaataaaa acagtcaatg attgaaaaac tctaaaaata atcttaggaa caaaccattt
    37501 ttcttttttt cttctattct gtttttttcg agtatttttg cgtggcaaaa gggtcacctc
    37561 aactaatggt tttatttcgc taattatagc aaataataga acaaaaaaac agacaaggct
    37621 gtttttggca ggaatttctt ttttaaaaga gttaaaacgt gagaaaatga tctttattat
    37681 aaaagagttc ttaagctttt ctttagagaa aatttcagtt actatggaga acagggcaaa
    37741 gaaaaatcaa tcattttctt tgtatatcat cttaccaata tataggaatt gttagtaaca
    37801 attgcctttc aaggaggaat ccatccatgt tattaggctc acacgtcagc atgagcggaa
    37861 agaaaatgct gttaggagca gcagcagaag cagccagtta tggatcttcg acttttatga
    37921 tctatacagg cgcccctcaa aacactagaa gaaaagccat cgaagagatg aatattgatg
    37981 ccggaaaagc gtacatggca gaaaacggtc taacaaatat cgtcgttcat gccccttata
    38041 tcattaattt ggggaatacg atcaaaccag aaatgtttcc ttttgccgtc caatttctga
    38101 gagaagagat tgttcgtgcg gaagctttag gcgctactca aattacactt cacccaggtg
    38161 ctcatgtagg ggcaggaaca gaagccggaa ttgctagaat tattgaaggc ttgaatgaag
    38221 ttttgacaaa agaacagacg gcacaaatcg ctttggagac aatggcaggt aaaggtacgg
    38281 aaatcggtcg aacatttgag gaattagcgc aaatcatcga tggagtaaaa ttaaatgaaa
    38341 aattatccgt tacttttgac acctgtcata cgaatgatgc cggttataat attaaagaag
    38401 acttttcagg tgtaatggaa gagtttgata agatcatcgg gttagatcgg cttaaagtac
    38461 tccatatcaa tgattctaaa aatccgcaag gttcgcataa agaccggcac gccaatattg
    38521 gttttggaac aatcggattc gacacgctga ataagatcgt ccatgatcca atgtttgaca
    38581 atatttcgaa aatcttggaa actccctatg tcggcaaaga taaaaagaaa gcttacgcac
    38641 catatggaaa agaaatcgcc atgttcaaag cacaaatatt cgatccagaa gtgtttcctg
    38701 agttattagc agaagaagtg atactctaag attttctatc tgacagcagc aaaaaaggac
    38761 caggcacatt gccttgtcct tttttgttta agaaacaaag gagtactttt tgcagtcttt
    38821 ttcatcatgc atcttctccc ccctcttttt aaatttagac aaacaaggta tactgttaga
    38881 aaagtaaaaa aacgaaaagt ttcacaagca agtggcaaaa cgtgattgga aggacgaaaa
    38941 gatgctgaac actttaaaac ccttgatcaa ccaactaaaa aagaaacata catactttat
    39001 tcttggcata gccctattat ttacaattat tcgtttgtat ttatatagta aagcaatcta
    39061 tggaacagac atgtcggcaa cctatgatga ccagctgctg attcgctatg ctcaaaatat
    39121 tttggacggt aaatggctag gggagtatac gactacaaca ctttccaaag gaatctccta
    39181 cagcttattt ttagtacttg cacataaact gcatctttct tatgctgttt tgttcggcat
    39241 gttcagtatt tttgccagta tattggttgc actcgcgttt aaaccgatcg tgaagaacaa
    39301 gtatcttctt ttaagtatct atttttattt tttgttttct ccgattagtt ttacacatga
    39361 atattccact cgaacatatc gtaatgccct cgtgattccg gctgttgaga tcattatcgc
    39421 ttgtttacta gctatttatt accgcaaata cggttctagc agaaaattgc tgccatggtt
    39481 tttagggctt tctgtcgctt ttcctttctt ttggttcatt cgcgaagatt ctatctggct
    39541 tcttcctttt actgtagtag ctttgggtat cagtttcgtc cagatcttgc tagggcaaga
    39601 cttttctttc aaagaagtaa agaagttaaa aaaacgactc tttcttctct cgaaacggga
    39661 atggctgaaa ctttcattgt ttttacttcc tatagttggc ttttccatcg tctatcagtg
    39721 gatcgaatat aaaaatgaga caacatacgg tattgcaacc atcaatgacc gttccagtgg
    39781 agaatttgga cgtttgatga aacaactgat ccgaatagat gatgaaacga acttgaataa
    39841 agaaaacagt gagatatggg tctcacatgc tgcactaaat aaagcattag ccgcatctcc
    39901 tacattccat actgtttcta cccgtattga cgaattatat acgactcacg cgtggactca
    39961 aggtggaaaa gtaaaagaat tacccggaga tatcatcttt tgggcattgc gagatgtggt
    40021 aagcgaatct ggttattacc aaaacaatgc aaaagaaacc aatgattttt ggaaaaaagt
    40081 caaccaagaa ttagaagaag cctatcacaa gggaaccatc aaaaagaaaa aagagttcta
    40141 tctgatggga tcaggagatg gaaagacgat gagtgatctg ccaatcgtat tcgatttcct
    40201 tcaatcagga tacgcttatg catggcgata taaagatttc catcaaggag gaaattatag
    40261 tttcggaacg caagaacaag tcaaacaggc tcaagaatta ttaaaccttc cgctaatgga
    40321 gaattggatc gatagtaatg aaccgagaac acctaatttc caattaacaa aatcagcaaa
    40381 agtcgcgaat gtcatcataa aaatttacca agttctggct attcccgtgc tgattgcttc
    40441 aatagcaggg atattactta tgatactagg aaccgtattt gcaaaagctg atcgtgccta
    40501 ttatagttcc tctttgattg tggtcaccgg attaatactg acacaattgg tttttctttt
    40561 cggtgtctcg tggttttgtt cttatgcgcc agaaaaaaag gattattttt taagtgtcta
    40621 cactggcgca ggcgtgccat taacgcaatt catcgtagta acaagcatgc tagttttcag
    40681 taaattaaat ctgaaaaagg ctttatcttc taaataaaaa gacccttggt agctagattt
    40741 ttaacctaac tatcaagggt ctttgtgtgg aaaaatcagt ttctattcga tttcttctac
    40801 cgtttcctgc aaacgctgtt catatttttt gtttccttta tataaatcac caatcgtcca
    40861 tgccaacagg agaaggacaa gaacaatgat tacataagcg atgtgatcag ccaatgctag
    40921 ttgagcagaa gtggcttgtt caccaaagaa actttcgatc tgtcctggta atcctcgtaa
    40981 gttcaagtaa gttagactaa tcacagagaa ccagccaaga agttttacga tgaatgaatt
    41041 tttaaatcgg ctacccatct ccgcttggct gttggtcatc atcagtaaag ggatcatcga
    41101 aaacggcaac gcaaaagcca agaacacctg ggattcattc atcaagttat tcaaagcggt
    41161 atgttcttcg atcgttcctt ttgtacttgt aaacaaaaca caaatcaata caggaatcac
    41221 agaaagcaat cgtgtgacca gtcttcttag ccaaatcggg atacgcatat ggatgaagcc
    41281 ttccatgatg acttgaccgg tcaacgtacc agtaatagta gagttctggc cagaagcaag
    41341 aagtgctaca gcaaataaag tggataagat accagatttt gctacagcaa tcaagatacc
    41401 attgctcata gctgatggat cagataaggc ttcatacaga ccaaaaaagg aaggatcttg
    41461 gacagaaccg gttttgaaga cagcgacacc catgatcaat agcagtgcat tgactagaaa
    41521 agccatcgac aattggatat tagagtccca agtagaaaaa cgtacagctt gtgctacatc
    41581 ttcttcgtct tggtgatcaa tcttccgagt ttgagaaact gctgaatgaa gatataagtt
    41641 atgcggcatg actgttgcac caataatccc taaagctcca gtcagcggag tttcgccgcc
    41701 gatgaccggt gagtctgaga atgtatgact gttagggata aagccagcaa ataaactgtg
    41761 ccaatctggg ttagacaagc caacttgata gacaaaaacg aataaaatga cgaaaattaa
    41821 gcagacaacc agtgcttcga tcttacgaaa cccgactttt gtcagtagta agagaacgaa
    41881 aacatctaat acagtaataa agacggcaat caccaatgga atatcaaaaa gtaagtagag
    41941 ggcgattgct gcaccaatga cttctgcgat gtctgttgcc ataatggcta attcagtcaa
    42001 gatccataaa atgacaccca atgtcttact tgtgcgtgct cggattgctt gggccaaatc
    42061 catttgggtc acgattccta attttgctgc catatactgt aaaagcatag caatcagact
    42121 agacatcaaa ataactgaca tcaataaata ttggaaattt tgtccaccag tgatcgaagt
    42181 ggaccagtta cctggatcca tataaccaac tgctactaat gcacctggtc cagagtaagc
    42241 aagaagtgtt ttaaaaaaac ttttcccctt tggtacatca actgttccat ttacttcagc
    42301 taaagataaa ccatttgtat gttcaataag tcgatgctta tgaaattgtt tgttggattg
    42361 attattcaag aaaaaaccac ctttcctatt tatctacgat tacattctac acctcaaaaa
    42421 gaaaaaatta aagaaaaata ttcggtatgc ctaatttatt ttcgtggcgc gtcttgttag
    42481 atgacgaaag aaattttgtt ctcctctaaa aaaaccacta ttttttgcat gaaactaaag
    42541 aatacgcctt tcttttttca ataaacttta gtaaaataag tcattgagag caattcggaa
    42601 atagaaagga gagatttata tgttatcaac aggtattgtc gtacttattg ctattattgc
    42661 tttgctaatc ggcgcagtag gtggcttttt cctagcgcgt aaatatatga aagactattt
    42721 agaaaaaaat cctcccgtta atgaggacat gttgcgatca atgatgatgt caatgggaca
    42781 aaaaccatct gagaagaaaa ttcgccagat gatgcagcaa atgaagaacc aagggaaaaa
    42841 ataggttctg acccaacgac tttttacggg ctgatttttt cagtccgttt tttattttgt
    42901 aatttgttag actattcaga ttattcagca aaaagacaag cacagacaat cctaggctct
    42961 tgataaagac aaaggaggag taaaatgtcg atttttagaa agttaggctg gttttttcgt
    43021 caggaaaaga aacattattt aattggggtt ttctcgctat tcgcagtggc cttggtacag
    43081 ttagttcctc caaaagtgat tgggatcatc attgatgaga ttgccgataa aaatttatca
    43141 gtaaagatca ttttcgggtg gatcttccta ttgattatcg ctgctttctt acaatatctt
    43201 tttcgttata tctggcggac gaatatttgg ggaagtgcag ctcggttgga gaaagaactt
    43261 cggcagcagt tattcaaaca ttttacaaaa atggacaatc tcttttacca aaaatatcgg
    43321 actggggatt tgatggctca tgcaacgaat gatttgaatg cgatccagaa tgtagcagga
    43381 gctggtatct tgacctttgc agattcagtg attacgggcg gaacaacgat cattgtgatg
    43441 attttgttta ttgattggcg cttaacactg attgcgctga ttcctctgcc tttgctggcc
    43501 gtcacttcac gagtgctggg gtcgaaactc catgatgctt ttcgtgattc gcaagaagct
    43561 ttttctagta tcaatgataa gacacaagaa agtatcactg ggatcaaagt cattaaaaca
    43621 tttggacaag aaaaagaaga tctagcggat tttgaagaaa agattgaaga tgcaattatt
    43681 aaaaacaaac gagtcaattt tctagactcc ttatttgatc cattcattac cttgattatc
    43741 ggtctgtctt atgttgcaac aattatttta ggtggaaagt atgtcttgga aggcacgatc
    43801 tcgatcgggc agatggtctc atttattagt tatatcggta tgcttgtttg gccgatgttt
    43861 gcgattggtc gattgttcaa cgtattggaa agaggaaatg cttcttatga tcgcgtcaat
    43921 gaacttttgc atgaaaaaac gcatatcgtg gaacaactgg gtgcagtgca gaccccggta
    43981 aaaggcgagc tgaatgtagc tatttcctct tttaattatc cgaaagaaga atcaccagca
    44041 ttagaacaaa tcaagtttgc aatccaagaa ggagaaacat taggtattgt tgggaaaact
    44101 ggtgcgggaa aaacaacgat catcaaatta ctgatgcgtg aatacgatga ttatcaaggg
    44161 aaaatccaat ttggcggacg ttcgatcaaa gaatattcat tgaatgcttt attaggatca
    44221 atcggctatg tgcctcagga tcacttcttg ttttcgatga ccattcgaga taatatccgt
    44281 ttttctaatc caaaactttc agaagaagaa gtagagcatg cggcttcttt agcatttatc
    44341 aacaatgaaa tcaaggaatt accaaaaggt tatgatacct tagttggaga acgtggagtc
    44401 tctttatctg gcggacagaa acaaaggatt tcgattgctc gagcattgat caaaaatcct
    44461 gaattattaa tattagatga tgcactttct gcagtagatg ccaaaacaga agaagctatc
    44521 ttgcataatt taaaagaaat aagaaaagag aaaacaacta tcattgcagc tcaccgttta
    44581 agtagcgtga tgcatgcaaa agaaatcatt gttgtcgatc aagggaaaat cattgaacga
    44641 ggaacccatc atgagctgct tgcactaggc ggctggtatg aacaaatgtg ggagaaacag
    44701 caattagaag cgaagataga aggaggcgag gcctgatgga tgaaaattat caatcggaat
    44761 ggacaaaatc gattccactt aaagaacaga aaaagatcat caaacgactg atgaagttcg
    44821 ccaaaccttt tagaacaacg ttcatcgttg ctatcttatt tgcgtttgct ctgtctgtga
    44881 tcaatgtcct attgccaagg atcatccaaa cttttatgga tgatcatctg gctaaacagt
    44941 cggctacgac acaagttatt ttgttttttg ctggtatgta cttatttgga gtcctagtaa
    45001 aaagtatcat ttggtttttc caatggtatt tgtattccat ggcttcattg aagacctatc
    45061 agtatattag ggtaaaatta tttgaaaagc tgcatacact aggtatgcgt tattttgatc
    45121 agacaccggc aggatcaacc gtttctcgag tgacgaatga cacagaaacg ctatttgaat
    45181 tttggtacgt ctttttgatg gtattgactg ggatctttgc agtcgtttct tcattcattg
    45241 ccatgtttca aatcaatgga gaaattgcct tgtggacttt ggtgttcttg ccgattttag
    45301 gaattgtcat ctggtattac cagaaattta gttctcgtat ttaccgaaat atgcgggaaa
    45361 aattaagtca gctgaataca aaattgaatg aatcgatttc cggcatgcgt attatccagc
    45421 agtttcgcca agaagctcgt ttagctaaag aatttgaaca agtgaacaat gagtatttag
    45481 acacgcgcta tgcgatgatc aaaacgaatt cgattctgtt aagtccgatc atcaattttc
    45541 tatatgcatt ggcgattgcg ttggcgttga ctttatttgg gatcgatgcg ttgcattctc
    45601 ccgtagaagt tggactgatc tatgcattta cgacttatgt ccagggattt tttaatccaa
    45661 tgtctcaaat gatggacttt ttgagcatct tcacagatgg gatggttgct ggtagtcgta
    45721 tcttgaagat tatggatacg gaagaatatg caccacaaca aaaccctgga gcagatcaaa
    45781 tgattacttc aggtaagatt gagtttcgca atgtaagctt ttcttatgat ggagagcaca
    45841 atgtattaaa caatatctct tttgttgcta atccgggaga aaccgttgca ttagtgggac
    45901 acaccggaag tgggaaaagc tcgatcatca atgtgttgat gcggttttac gaattttatg
    45961 aaggtcagat attgattgat gatcatgaca ttcgagaata tccaatggaa gagttacgta
    46021 agaaaatggg gctggtcttg caagatgctt tcttgtttta tggggatatc gcaggaaata
    46081 ttcggatgat gaatccagct atcacagacg aacagatacg ccatgcggct gagtttgttc
    46141 aagcaaacaa attcatcgat gaattaccaa aaggatatca ctcaaaagtg atcgaacatg
    46201 gtgccagcta ttctagtgga caacgacagc tgatcacttt tgcgcgaaca atcgtgactg
    46261 atcctaaaat tctagtattg gatgaagcaa cagcaaatat cgatactgaa acagaaggat
    46321 tgatccaaga aggattggcg aaaatgcgac aaggacggac aacgattgcg attgcccatc
    46381 ggctgtcaac gattcgagat gcagaattga ttttagtttt agacaaaggt catatagtag
    46441 aacgcgggaa tcatgaaaca cttctagcgc aaaatggttt gtatgcagat atgtacaaac
    46501 tgcaaagtag tggtatataa aagatgttgt gacagtagca ttttgaccta agcactagag
    46561 tgaaaataaa acatagcttc ccatattttt catctgtgag agttagtgtc gtagttacca
    46621 gatttaaaaa agacgacgtc agctagtcag aagtgcctaa tagcccctaa gaaagcgttg
    46681 acaaaatcgt ttgctttcga taatataaag aaaacgatac aacttggata gtgattgcct
    46741 gatgcaagct aaacctgatg agtctcccat ggtttcatgg acggcttttt gggtttttct
    46801 ttttgttttg gatacagccc tatatatcat ggaaaggagc aaaacatgct gattgagaaa
    46861 gtactgaata acaacgtcgt aataacaagg gatgaaagag atcgggaaat gattgtgatg
    46921 ggaaaaggat tggcattcaa aaagaaggtg ggtgacccga ttcttgactc atgcatcgac
    46981 aaaaaatttc agttgacaaa tgacggactt tcacaacagt tccaagaatt ggcacaagcg
    47041 attcctcttg agtacttaga aatttcttgt gaaatcattg aatatacaaa agaggctctg
    47101 caagtccatt taaatgattc tgtgtatatt tcattgacgg atcacttgta tacagctatc
    47161 gaacgtcaaa aaatggggat ctttgtgcca aatgtattgc tgtatgatat caaacaactg
    47221 tttcctaaag agtatgccat tgggaaaaaa acagtgaaga aaatctcgga taaataccac
    47281 atcaagttat cagaagacga agccggattt atcgcattgc atttagtcaa tgcacaaggc
    47341 attcaaagcc agcaagacaa tacctacctg tttaccacaa caatacagga tattttaaat
    47401 atcgtccgct attactataa gattacattt gatgaagatt cagtccactt ttttcgattc
    47461 gtcacacacc tgcgtttttt tctgacacgt gtcctagatg gagcgaaatc agaagatgga
    47521 gaagtttctg aggaattgtt ccaagttatt caaaaaaaat ataaggatac gtttggttgc
    47581 gttgagaaaa tagcagactt tttaaccggg gctttcgact accagatgtc cacggatgaa
    47641 aaaatgtatt taacgatcca tactgcgcgt ttagtgcatg agaatcgttg taaataaata
    47701 aaaaaggagg acaaattaac aagaacgtat gaaataaggg tagtgacatt cagttggcta
    47761 aaccttccac taattaattg gagggaatag aaatgggaaa ataccaggaa ttagcagaaa
    47821 acatcgtaaa gaatatcgga ggaaaagaaa atatccgtag cttgacacac tgtgtgacgc
    47881 gacttcgttt caaactaaag gaggaaaata aagcaaagga tgatgttttg aaaaagatgg
    47941 aagggatagt caccatcatg aaaagcggcg ggcaatatca agttgtaatc gggaatcatg
    48001 tgccagatgt ctatgcagaa gtactgacag tagccgggat ttccgatgaa gcagaagaag
    48061 aggtttcttc aagtagtaat ctgttcaatc gattaatcga catattaagt ggctgtttcc
    48121 agcctttttt aggtgctttg gctgcagcgg gaatggtcaa aggattaaat gctttgttct
    48181 tgtttctcaa attttatact gaaggatcgg gtacgtacat catgctgaat gggatagggg
    48241 atgcaatttt ttatttcatg ccagtgatct tagggtacac agcagcgaaa aaatttcatc
    48301 tgaatccgat ggtggggctc gtgattggtg cagcactttg ttatccgact gtacaaggag
    48361 cagcactaca aagtggtttc cctgatggca gtcctgcgcc ttatagcttg ctgggtcttc
    48421 cggcttatga aacatttttg ggtatcccat gggtgggcag cagttatact agtagcgtcg
    48481 tacctgttat cttcattatc gcatttgccg gacaagtcca aaaaattgcc aagaaatgga
    48541 ttcctgcagt cgtccagacc tttttggttt ctttttctgt gttattaatc gcacttcctg
    48601 ctggcttttt gattatcggt ccgattgtca gtatactgac agatctatta agcacgggat
    48661 tccaagcatt gatggacttt tctccagctg tgtatggtgc agttctaggg tttctttggc
    48721 aagtactggt gattttcgga cttcattgga gtattatccc tcttgcgatt atgcagctag
    48781 cgcaaaatgg gtggagtcag atgttagtag gcgtttatgg cgcgagtttt gcacagacag
    48841 cagtggtatt ggcgatgtat ttcaagttca aggatcaaaa aatgaaggcg ctttgcatgc
    48901 cagctgtgat ttcaggaatc ttcggcgtaa cagaaccggc tatttatgga atcaccttac
    48961 cgaagaagaa gccatttatt tactcgatga ttggtggtgc tgtttcagga atctatttga
    49021 tggcatctgg aacaatcagc tacataatgg gcggattagg gatttttggg gtggtaaact
    49081 acatcacgga aacagacgcc agtggtatgt ttcaagcgtt tatcggcatt gctattgctt
    49141 cggtaatcgg gttttcgctg acttttttct tttggaagga tgaagcaggt gaaacagatg
    49201 ctatacagaa aaaatcaggt aaagaaattg taaaaacacc gatacaagga caaatcgctc
    49261 cactaaatgc agcgaaggat gcagcttttg cacaaggaac actaggtcga ggaatcttaa
    49321 tctaccctga aaaaggagaa gtacgtgccc cttttgacgg aacagttatg accctgttcc
    49381 cgacgaaaca tgcaatcgga atggtttctg aaacagggct ggaattgctg attcatgtcg
    49441 gattggatac tgtgcagttg gaagggaaat attttgaaag cttagtgcag caaggagaaa
    49501 gagtgagaca aggcgatctg ttgctacgct tcgacaaaaa gaaaatcgaa aaggaaggat
    49561 acagtttaga aacacctgtg atcgtcacca attacacgga ttatttggat attttggaaa
    49621 accaagggga gacggtcggg ccagacgatg cacttatcac cgcactgacc tgaacggtta
    49681 ggtgaagaat ggactaggct taactattct ttttattcca cttctttatt ttcaaaattg
    49741 aaaggctctt tcatgatggc tgagctgata gggcgtttat cgaatttttg accgacagaa
    49801 attagatgga ctaaattctg ttgataattt tctgcaaaaa cacaactata taacacgtct
    49861 agaagataac aaattgatgt attgatcgta aaattaccaa tttttgaata cagtcgctcg
    49921 cgtgtcgtaa gtcgcaaagc ggctgtactc attgcagata gcgttgaatc accgatactg
    49981 gtcaaagcta aaattggaac atcattttgt ttcaatattt ctgcggtacg aaggatcaca
    50041 ttgttttcac ccgtataaga aatcagaatc ccgcacatat cgctcgtaca attgtacgct
    50101 tcatagaatg attcaccaaa agtggtgaca attgtgacat ccattttgat gcgcttcatt
    50161 ttcagcatga aatcttgaga aatcaaagta ttcgagttac tggcgaagat cacgattttt
    50221 tttgcctgga gcagtaaata tttagctttt tgcagttggt catgatgaat gagagaaagt
    50281 gtatcatgaa tcgtcatctg ttctaaagaa gccattttat ttgcgattgt cataataccg
    50341 tctgtggtgg aaaaaggaag attcgcatct acgtcttgaa aattcccttc aagataggct
    50401 gtttcagcta aaaaagcatt acgaaaactg acccagccat caaaacccat tttttttgct
    50461 acacggatga gtgtagacgg gtggacataa catcgctcag ctatcgcttg gatggtcatt
    50521 tcgccaagtg ctggagaatc gcttaagaga aactggatca cttcattttc tgaaggagaa
    50581 aaggagattt ctttgatttt ttcacgtaat aacatgtaga taccttcttc ttattttttt
    50641 acgtaaatta taactttttt gaaaatgttt tgtaaacgga tttatactat ataacttaaa
    50701 ataggctttt tttgacaaga tatttacaaa aatccactag aaaacagtaa cttttgtaaa
    50761 tgttactgga aagaaacgga tttctattgt ttgttttgtt tacaaaaaag ataatgaaag
    50821 tgtaaaaaag taaaggagtg agaacatggc aaaaggaatc aaaatcgcta cgattggtgg
    50881 aggcagcagt tacacccctg agttgatgga aggatttatc aaaagatatg aggaattacc
    50941 gatacgagaa atctggctcg tagatgtaga agaaggaaaa gaaaagcttg agatcgttag
    51001 tcagatgtct cagcgtatgt gggatgcttc tccatatgaa gtcaagatct atgcaactct
    51061 ggatcgggaa gaagcattga aagatgcgga ttttgttacg actcagtttc gtgtcggtca
    51121 attagatgca cgaatcaaag acgagcggat ccctagttat tatgggatga ttgggcaaga
    51181 aacaaatggt gctggcggga tattcaaagc ttttcgtacc gttccagtcg ttttggcaat
    51241 cgttgaggac atgaagcgtt tatgtccaaa tgcttggctg atcaatttcg cgaacccaag
    51301 tgggatggtg acagaagcag ttatcagata tggcaaatgg gataaagtga ttggattatg
    51361 caatgtgcca gtgatggcga tgatgacaga accagcaatg cttggcaaga aaaaagaaga
    51421 gctgatctac aagtttgccg gtctaaatca tttccattgg cacaaagtag cagataataa
    51481 aggaaatgac cgcacggcag aattgattga tcgtttatac gatgaagata atggattacc
    51541 gaaaaatatc tttgatatcc cgtttttcaa agaacaatta aaacaaatga acatgatccc
    51601 ttgtggctac caccgctatt actatcgtga agaagaaatg ctggaacatg ctttagaaga
    51661 atatcaaacg attggtacaa gagcgcagca agtgaaagaa acagaagcag agctatttga
    51721 attatacaaa gatccagaat tagaccataa acctgaacaa ttgcaaaaac gaggtggcgc
    51781 ttattattca gacgctgcct gtgaaacgat tgcttcaatc tatggaaata aagaaacaca
    51841 gatcgttgta tctacaaaga atgatggagc tgttcctgac ctgtcggcag attgtgttgt
    51901 agaagtcact gcctatgttg gcgcacaagg agcgagaaat gtagcgtttg gttctcttcc
    51961 tgctgctgaa agaggctggt tgcaagtaat gaagaatatg gaattgctga cgatcgaagc
    52021 agctgtgact ggtgattatg ggacagcttt acaggcgttt acgatcaatc cacttatacg
    52081 atcaggaaag acagcaaaac ggatcatgga tgagttgttt attgcacacc agcagtattt
    52141 accgcaattc aaggaaacaa tcagccgatt aaaagaagaa ggaatcgaag ttcaagatga
    52201 actggcaaga gaattatcag gtaatacaca tataatggag gaagtataat ggggttcaga
    52261 aaagattttt tatggggcgg tgctacagca gccaatcaat gtgagggcgc ttatgatgaa
    52321 ggtggacgcg gactagcaaa cgtagatgtt gtgccaatcg gaaaagaccg ttttcctgtt
    52381 atcaccggaa agaaaaaaat gtttgaattt gatgaggatc atttttatcc agcaaaaatt
    52441 gcaatcgata tgtatcatcg ttataaagaa gatattgctt tgtttgcaga aatggggttc
    52501 aagacttatc gaatgtctat cgcctggagt cgtatttttc caatggggga tgagaaagag
    52561 ccgaatgaag ctggcttgaa attttatgag gatgtcttta aagaatgcca aaagcacgga
    52621 attgagccac ttgtgacgat tacgcatttt gattgtccaa tgcatttgat caaagaatat
    52681 ggtgcgtggc gttccagaga actcgttggt ttttatgaaa atctgtgtcg agtcatcttc
    52741 aatcgctata aaggacttgt caaatattgg ctgacattca atgagatcaa tatgatcctt
    52801 catgcaccat ttatgggcgc agggctgtat tttgaagaag gagaaaatga agaacaaatc
    52861 aaatatcaag cggcacatca tgagttggtt gcaagtgcca tcgcaacgaa gattgctcat
    52921 gaagtagatc cggagaacaa agtaggctgt atgctggcag caggagcata ttatccatac
    52981 acttgcaatc ctgaagatgt ttgggcttct agaaaatcag atcgagaaaa ttatttcttc
    53041 attgatgtcc agtcacgagg agaatatccc gcttatgcat tgaaagaaat ggagcgaaat
    53101 ggcattcaga tcgaaatgga accaggggat gccgcattgc tgaaagaaca tactgttgat
    53161 tttatctctt tttcttatta ttcttcacga gtttcgacta ccgacaacga actcttggaa
    53221 cagactgcag gaaatatctt tgcttctgtc aaaaatccat atctgcaagc aagtgaatgg
    53281 gggtggcaaa ttgatccatt aggcttgaga ataacgatga atgatattta tgatcgttat
    53341 caaaaaccat tatttattgt agaaaacggc ttaggtgcag tcgatacgcc agatgaaaat
    53401 ggttatgtgg aagatgatta ccgaatcgat tacctggcag cgcatatcca ggcgatgaag
    53461 gatgcagtag aactagacgg agtcgatcta ttaggctata cgacttgggg atgtatcgat
    53521 ttagtatcag ctggtaccgg tgagatgaag aaaaggtacg gattcattta tgtcgatcgt
    53581 gataaccaag gaaatggcac attagcccgt tcaaagaaaa aatcattcaa ctggtataaa
    53641 aaagtaattg attcaaatgg agaaaatctt tcgaacaatt gatcaatgat ttataaaagt
    53701 ctattgtttt tcagcggatt tttcgagtat aataaagcta ttcgagaaac gcaagcagaa
    53761 caatagactt tttttcgcat tggctgtaaa gtatgcttac ttgattaagt aaaggagaat
    53821 ctacatatgt atgatgtaat cgttattggc gcaggtcctg ctgggatgac tgctgctttg
    53881 tatgcttcac gttcaaactt atccgtattg atgatcgaac aaggtgcccc tggcggccaa
    53941 atgaacaata cggcagaaat cgaaaattat cctggattcg attcgatcat gggccccgat
    54001 ctagcttata agatgtatga aagtgtctca agatttggga cagaaaatgc ttatggaatc
    54061 gttcaagata tcaaggatca cggcagccat aaagaagtca tctgtgaaga taaaagttac
    54121 gaaggaaaaa cagtcattat cgcaacaggc tgtatccacc gtaaattagg cgtacctggc
    54181 gaggaagaat ttgctggacg aggcgtttct tactgtgcag tctgtgatgg tgcgtttttc
    54241 cgtaacaaac gtctagtagt catcgggggt ggggactcag cagtagaaga agccatctat
    54301 ttgacacaat ttgcttctga agtagtgatc gtccaccgta gagatgaatt acgtgcacaa
    54361 aagatcatcc aagaccgtgc atttgcaaat gaaaaaattt cctttatgtg ggatacagtc
    54421 gttgacgaaa tcgttggaaa cgaaatggta gtgacaggtg tgaaagcacg taatgtcaaa
    54481 accggcaatg aatttgattt agcagcagac ggagtattca tctatgttgg actggatcca
    54541 ttaactgcac cttttagaga agcaggtttg acgaacgaag ctggctggat tccaacagac
    54601 aacgaaatga aaacgaatat gccaggcgtt tttgccatcg gagatgttcg tgaaaaagat
    54661 ttgcgacaaa tcactacagc tgttggtgac ggcggtattg ctggacaaca agtgtataaa
    54721 tacttggagt ctttagaaga aacaacagca taagtttaaa aagagtgaaa gaacggtttc
    54781 aattgttctt ttactctttt ttttcgcgtg aaatccactg aatccgattt atgtgaatac
    54841 ttgcaatcat gcttgataaa agaatccttt cttgatttaa gcgttttttg gtcctcatac
    54901 tttcatatct aataagtgaa tgctatactt attaagaacc atatttcaga aagaggtgtt
    54961 attttcatgt cttgggaaca agtgtatgaa caatgggtac atgaagaaaa tttagaagaa
    55021 aacttaaaaa aacaattaaa tgatctgggt gaagatcctg aaaaacttga agatgctttt
    55081 tatgcaccgt tggaattcgg tactgcaggc atgcggggaa tcttaggacc tgggatcaat
    55141 cgaatgaaca tctatacggt aagacaagca acagaaggac tagcacgttt catggataca
    55201 caaggtgaag aaacaaaacg ccgaggtgtc gctatcgctt atgactcacg ccatcagtca
    55261 ccagaatttg caatggaagc agccaaaaca ctggcacatc acaatatccc gtcttatgta
    55321 ttcgaaagtc tgcgtccaac accagagctt tcttttgcag ttcgtcattt gaagacgttt
    55381 gcgggaatca tggtaaccgc atctcacaac ccagcggctt acaatggata taaagtctac
    55441 ggagaagatg gcggacaaat gcctcctgca gacgcagatg cattgacgaa atatgtccgt
    55501 gaagtcagca atccgctaaa agtcgaagta ttatctgacg aagaagctaa acatagcggg
    55561 ttgatcacga tcatcggaga agaagtggac gctgcttatc tagaagaaat caaagcagtg
    55621 acgattgatc gtgaattggt tgaaacaatg gggaaagatt tgaaacttgt gtacacgcca
    55681 cttcatggaa cagggaaaat gttgggcgaa cgtgcgttga aacaagctgg attcgaacaa
    55741 ttcgtactag ttcccgaaca agctgtggca gatccagatt tcactacggt caaatcgcca
    55801 aatccagaag aacattcagc ttttgaatat gctatacgac ttggagaaaa agagggagct
    55861 gacttgctga ttgcaacaga tcctgatgca gaccgtttag gcgcagcggt tcgtttgcca
    55921 gatggttctt atgaagtatt gactgggaac caaatcggag cattgtttgc tcaatatatt
    55981 ttggaagcac atcaatcaag aggcacttta ccagaaaacg cagcggtatt gaaatcaatc
    56041 gtttccagcg aattgcctac agcaattgcg gaacactacg gtgctactat gttcaatgtg
    56101 ttgacagggt ttaaattcat tgctgaaaaa atccaacaat ttgaagaaga ccattcacat
    56161 acttttatgt ttggattcga agaaagttat ggttatttag ttaaaccttt tgttcgcgat
    56221 aaagacgcga tccaagcatt gcttttatta gcagaagtag cagcttacta taaaaaacaa
    56281 ggcaaaacgt tgtatgacgg cttgcaaacg atttttgaaa cctatggcta tttcgcagaa
    56341 aaaacgattt ctgtgacaat gagcggacaa gaaggttctg cgaaaatctc tgctttgatg
    56401 gaaaaattcc gtaaagaagc accgacagaa tttgccggag caaaagttat tcaaacagaa
    56461 gactttaaag aattgacgag aacagaccgt gaaggaaacg tagaaaaact aacaacaccg
    56521 ccatccgacg tattgaagta tacattggaa gaaaatggct ggatcgctat ccgcccttca
    56581 ggaactgagc cgaaaatcaa gttttatatt ggtgtaaaag gaagctctac agaagacgca
    56641 gccgaaaaag tagcctctta tgaagcgatt atcaaaaaga tgacagaaga ataaaaaact
    56701 tgagactgat ggaaaaagtg gtaaacttta gaagtcagtc ttttttcaag ttggaggtga
    56761 atggattgcc agacacgcaa aaatcaaaag tagagaaagt cagtcaatta ttcaaaatgt
    56821 tgagtgaccc cactcgtctt aaaattctgc tatatctgaa agacggggaa caaaatgtga
    56881 cagcaatcac ccaagcagtg gaaatggagc agtctgctgt atcgcatcaa ctacgtttat
    56941 taagagaaaa tcatgtcgtc aagtctcatc gcgagggaaa agcgattttg tatagtcttg
    57001 atgattctca tgtactggat attttgaacc agacactcaa acatgtggaa catcaataac
    57061 gataggtgca aatagataaa cactggagtg tgacaacgaa atttcttcgt tgtcacactc
    57121 cagtgttttt taagaaaaag acaaaaatga ttaatcgctt ttttctgttg tttcagttcc
    57181 ataataacta tgatcttcta ggtctaaagc attcaaaata agcgaagccg tttcttcaat
    57241 agataaagat gccacattga tcactacaca tcctagtttt tcataaagat cattcgcaaa
    57301 atcaagttca gctctaattt tttcgatatc ggaataagca gtatcagggt ttaatccgta
    57361 agagcgcatc cgttctttac ggatattatt taaaatatct gggttattcg ttagtcccac
    57421 gattttttta ggatcgatct cccaaagctg tttgggaata tgtgcttgtg ggatcaaagg
    57481 taaattggca acttttaaat ttttgttagc taaaaacaag ctcaaaggtg ttttggaagt
    57541 tcgggatacg cctagcaaaa cgacatctgc ttctaaaaaa ccacgaggat ctttcccatc
    57601 atcgtatttt acagcaaatt ccattgcttt gatccgtttg aaatagttct cattcaataa
    57661 atggagggca ccaggttgcc gaattggctt gataccagtt aaacgttcaa tttctgatat
    57721 cggtggcgtc atcacatcaa aactaaataa ttgatgttct tcacaaaaag aacgtgttat
    57781 ctcgatcagt tcttgattga ttaatgtatg caggacaagt gctttttctt ctaatgcatc
    57841 ttgcaatgcc tgccttaatg ttttttcatc tgtcacgaac gttctgcgga ataggttgaa
    57901 ctcaacggta ggatactgag ccatagtagc ttgcgctagt tttgtcgcag tttctccagc
    57961 agagtcggag atgacaaaaa aagtaacgat ttctgtagaa tcggaagaca tggataaaac
    58021 ctcacttgca ttttttttat gtttattata ccatactcta gaatgcgtac ttcgtaatca
    58081 ttttgatttg gaggaataag tcatgaaaaa acagacattg atcgaacaat cattagaaac
    58141 attgaaaaat aacggtttta aatatactaa aaaaagagaa gcattgttaa cttatttagt
    58201 gaagcgtaac cgctacgtat ctgctaaaga agtttttgac tatatgaatc aggaattcaa
    58261 aggggtaagt tatgatacga tttaccggaa tctccatgat tttgcagaga tcgatttact
    58321 ggaagaaacc gatttaaatg gagaaatgaa gtttcgtttt cattgctgtc aggggaaaat
    58381 cggccatcac catcatttta tctgtacagt gtgcggaaca acgaaagaaa tccatatgtg
    58441 tccgatgaat tatttcgaag aacagctagg tggatgcacg atcgaagggc atagattcga
    58501 gattttcgga agatgtgaaa attgtcaata aggatttaaa taaaataaca tttgataatt
    58561 ttaaaaaaaa gcaagatttc cttgacggtc aaaacagcat tagatataat atttacagga
    58621 cagtcttgtt ttttgagata tatttcaata acaattacgg ttacttttta agctcggagg
    58681 gagggaatta acatgtcaaa aacagtcgtt cgcaaaaacg aatcacttga cgatgctctt
    58741 cgtcgcttca aacgttccgt gtcaaaagcg ggtactttac aagaatctcg taaacgtgaa
    58801 ttctacgaaa aaccaagtgt aagacgcaag aaaaaatctg aagcagctag aaaacgcaaa
    58861 aaattctagt tctgtgatga attggagttg gtagtgtgtc actactaagt agattaaacg
    58921 atgacatgaa agcagcgatg aaagcgaaag ataaggaatc tttacaagtc atccgaatga
    58981 tcaagtcatc tatacaaaac gagcagatta aagaaggtca cgacttgaca gaagaagaag
    59041 aactaacggt gttgtctcgt gaaatgaaac agcgacgtga ttctttgcat gagtttgaag
    59101 aagcaggacg tgacgattta gctgaaaaag taaaaagtga aattgtaata gtcgaaaaat
    59161 atatgccgga acaactttcc gacgaagaaa ttcgacaact tgttcaagaa gcaatcactc
    59221 aaactggtgc ttcatcaatg aaagaatttg gcaaagttat gggtgcaatt atgcctaaag
    59281 tcaaaggaaa agcagatgga aaccaagtga atgcgattgt gaaagaacta ttacaatctt
    59341 aattttatca tttaaactgc ggacagtgat tatccgcagt tttttgtgtt cgtaaaaaaa
    59401 gaactaaaaa acagctagaa gaaagaatct tattctttct tctagctgtt tttttcctgt
    59461 ttaatatctc ttatgttaaa ttgtgtttga tttggttatt cttctggtaa ctcacttgct
    59521 tcttgtttat atcctgatac gcgatataca taataaaaga gcaagctgcc agcgtaacca
    59581 agcaacgttg ggacgaccca gccaagacct aatgcagcaa aaggaacata atgatgataa
    59641 aatcctagta agcttgctac gacagtttgc tgactcacta atgcaggcga atttgccaac
    59701 atatccaata cggctggaac ggcagaaaag aacatcgtta cttgatagac aaatggactc
    59761 ttttggaaga attttgctgt taaggaaagt aagattaacg caagtgacaa tggatacaaa
    59821 agcatcaata ctggtaaaga ccattggatg atattatcca atccggcatt cgcaacgaca
    59881 aaagagacaa aagtcgttaa ccgcagccat gtcatataac tgactttagg gaacagttta
    59941 tggaaatctt gtgcaaaaga aacaacgagt cccatagcag tagtgaagac acctaatgtg
    60001 accattaccc ctaagaagct agcaccgaag ttacctaaat aaaaattagt gatctgagaa
    60061 agtgcagttc cgccattttc tgataaagac atcttattca aactcatcgc accgagaagg
    60121 accagaccaa aataaatcat gacttctaac gcaacgctca ggctaccagc ttttgctgtt
    60181 aattctgtga cttttttatc tttaaaacca agatcacgaa ctgcatggac aaaagtgaca
    60241 cttaaagcaa gtaaagctac tgcatcaacc gtgttgtatc cttctaaaac gccatttgtc
    60301 aaagcgttcg tctgataaga atctgcagca gattggttta gattccccat gggttggaat
    60361 aaagaaacga caaaaatgat agctaataat gcaagaaaca aggagtttaa atactttccg
    60421 acatatttga ccaaacgtgt tggatgtaca gtaaggaaat aagcaagtaa aaagaaaaga
    60481 gcagagaata aaaacatacc taatgaatca tatttttcag gcaaaaaggg tttagcagcc
    60541 atttcaaaag cagttgctgc tgtccgcggt gtaccaaaga atggtccgat cgttaaatga
    60601 acaaggatca agaacaaggc agcataccat tttccgacag gtttagctaa gtcatacaga
    60661 ccatcacttt ttgtcactac tacagctaag atagctaata atgggaaaag agcgcctgag
    60721 atggcaaatc ctacaccagc gctgatccag tttgatccag ccatttgacc taagtgtaca
    60781 ggaaagatca gattacctga cccgaagaac atcccgaaga taagtgaact gaccatcaat
    60841 aattgcttcc atgaataagt ttttgtttct tccataaatt tttcctccaa taattatcat
    60901 tttgagtaac aaaataaacg ttgcagaaac tagaaatacc actaatatca gattccatga
    60961 aaaccaccac cttaaaatat aaaaaaagcc cttttccact tgggaaaagg gctctagatt
    61021 ctagaacggt accacctttt ttcgcttaaa aaagcttctt cattcacgga cgcttttcga
    61081 taaagttatc cgctagcctg ataatggagg cagccacaat gatctacgtt ttcgacattg
    61141 actcggaaat gatgttcgtc tattcgattt attgtcattt ctcacttaca tgactcactg
    61201 ggaataaatc actgaatagc ctactgtttt cctcgacgct ttgctgtata tttatttgtt
    61261 gacgttataa tacacctgtt ttttttgaaa tgcaagaata tttcaaatat tttgttttct
    61321 ttttttgaaa caagaaaaat acccagagaa tacttgctaa gttagacgga atacttgtcc
    61381 tctatcttat gcatagctta catgatcagc tttttttatt caaacgagac ctttagagaa
    61441 tggaagcggc tagtttttta acgtttcttg gtacttatgg ttaagcaact cttttagaac
    61501 cttttcttat ttgctatata gtttcttctg agtatggtaa aataggaaag aatgaatcga
    61561 aaaaaagggg atgtctattt ttgacggaag agtctagttc tttagagatt agattgacgg
    61621 ctgctgatga tgtcagcatg cttttaggtg cacacgacaa gcatataaaa ctgattgagg
    61681 aaacaacgga aacaaccatc catacacgtg gagaaatcat tcagatcatt ggtgagcaat
    61741 cccagatttc cttggctgcc tcagtcattc ggacattaca ggaattgatc aaacgaggaa
    61801 tccacgtaag tacgcccgat gttgtgacgg cattgaaaat ggggcaaaaa ggtacattag
    61861 attattttgt tgagatgtat gaggaagaga tcgtcaaaga ccgtaatgga aaacctatac
    61921 gggtaaaaaa cagcggccaa aagaaatatg tcgaatcggt agccaaacat gatatcgtat
    61981 ttggcgtagg accagccggt acaggaaaaa cttttcttgc agtagtatta gcaatcgctg
    62041 ccttgaaaaa aggtgaagtg caaaaaatca ttttgacgcg gcctgctgtg gaagcaggtg
    62101 aaaatctagg ctttcttccc ggggatctaa aagaaaaagt ggatccttat ctgcggcctg
    62161 tttatgatgc tttataccaa atttttggat tggatcatac gaaccgattg atggaacgag
    62221 gcgtaatcga aatcgcacct ttagcttaca tgcgggggcg aacattggat gatgcattcg
    62281 ttatcttgga cgaagcacaa aacacgacag tcgctcagat gaaaatgttc ttgacccgtc
    62341 tcggttatca atcaaaaatg attgtcaatg gggatacaag tcagatagac ttgcctcgag
    62401 ggacgacaag tggtcttgtt catgcagaac gaacattaaa gcaaatcaag aaaatcgatt
    62461 ttgttaattt tgaagcaagt gacgttgttc ggcaccctgt agttgccgaa atcatcaaag
    62521 cttatgaaaa ggcagatctc catcaagaat aagctttgct taggaggata agcacatgtt
    62581 gaataaaaca ctgcagaaac tacaagaaaa acttggaaag gcagcattgc ctttcctgct
    62641 gttcttgttt tttatcatta tctgcggcgt tacatttagt agtgtcaaac aaaaggccaa
    62701 tgatttcaga gaaggccaag tagcagaaga aagtatccgt gcgaacaaaa cgatcgagaa
    62761 cacggaagaa accgaacaaa aaagaaaact ggcagcagaa gcagtcactc cagaatacac
    62821 ttaccaaaaa gatcttgcag atgaccagaa caatcggatc aagcaactat ttgaattgat
    62881 cgataagacg aatgatgcca tcaacaaatc ttatgacgaa aagattgata aggcaaagga
    62941 agatgaaaat atcccaaagc ctactacaga agagcggatc gccgcgctga agaaaaattt
    63001 tgaaaatgtg aatgcagaaa atgttgtgtt ttatcaaaaa ctaccgaaca atttttattc
    63061 gacgatattt gaaatgactg aaactgagat tcatactgtg agggatgaga gtctgaagct
    63121 cattgacgaa cagatgagca aacaagttcg tgaaagtgaa ttggaagctt ttaaacaaga
    63181 agcagaagag caaatccaat atttgaatgt cacaccagca caacaacaaa tgattcgcta
    63241 cttagtggat caaggtatcg tagtgaatga cgtattgaat gagaaaaaga cagaagaatt
    63301 gaaacaatcc gcacgagaag ctgtacaacc agtgatgatc ttccaaggag aaatcattgt
    63361 tcgtgaaggt aatcaaatcg atgcttcagc tatgaaaaaa ttggaattac taggactgac
    63421 taatcaaaca acttcgattt ttccgctaat tgccatggtt ttagctgttt tgcttcaaat
    63481 cggcgtactg atttataatt cacttcaatt ccaaaatgca ggagaaagaa caaaatacgt
    63541 gcttttctat gtgacagcta tgtcagtcag catagtgctg atgaaatttt tccaattatt
    63601 ccaaacggaa caagctactt atatcccgct gttttatccc gctgcttttg caccacttgt
    63661 tttaagcttt ttcttgaatc gaagagcagg gatcatggct ggtattttcc aagcagtatc
    63721 cgcacttttc attttttatg attcgattgg cacgaacttt ctaacgatta tcttgatgtc
    63781 ttatgttttc tctgggctca tggcaacgat tgtcagacgc aaacggatct cagaacaagg
    63841 attatctgct gccatgtggg tcattatttt tcctgtgatg atggatgtca ttttgatcgt
    63901 ctatcaagga atgagctttg gtgatgcaac gacttggtta atgctcgtct gcgggttcac
    63961 tggtgcactc ttctcattct tgctgacgat cggtctacac ccatatattg aattgatggt
    64021 caatgatgac agtgtaattg tattaaatga actcagcaat ccaaatcatc ctttattgaa
    64081 acagttgctg gaagaagcgc caggtactta tcatcatagt atgatggtag ctaatctaag
    64141 tgctaacgct gtagcagaaa tcggcggacg ttctttgcta actcgagtag cttgctatta
    64201 tcatgatatc ggcaagatca aacatgctag ctttttcgtt gaaaacttgc cttcaggagc
    64261 ggaaaacccg cacaatttct tattgccaga agacagtaaa catattatct ttggacatgt
    64321 gacagatgga gccaaaatat tggaagatta taatatgccg caaatggtga tcgatatttg
    64381 caaacagcat catggaacca cgctaatgcg ttatttctac atcaaagcga aagaacgcaa
    64441 tccggaagta acagaagagc aattccgtta tcctggacca aaaccgcaaa gtcgtgaagc
    64501 agggatcgtc aatattgctg acagttgtga ggctgcagta cgggcaatgg atcatccgac
    64561 gagcgaaaaa atcgaaagtt ttgtccataa tcttatcgaa gagcgtattt ccgatggtca
    64621 attagacgat agtggactga ccttgaaaga aatccgaaaa gtggaaaaat cattaatcag
    64681 cggtttaagt agcaccttcc attctcggat caaatatcct aaaatgaaaa cagaagttga
    64741 gaagataaag gaagaacaag aagaatagaa agaagcgatg tataatggat attaccttta
    64801 tggatgaaac aaaccaagtc tcagaagaga aaatgaaaga aatcgatgac ttgctgcaat
    64861 ttgcagcatc ttatttaaag ctgccagagg aaacagaaat gtctgttact ttcatggaca
    64921 atgcggcaat ccaagtaatc aatcgtgatt accgtggaaa agatgcaccg acagacgtca
    64981 tcagttttgc tctggaagaa gaaggcgaag acgaaatccc agtgattttt gaagatggag
    65041 agaatccatt acctcgtgta ctaggagaca tcatgatctc tattgaacgt gctgctgaac
    65101 aagcagaagc ttacggccat tcatatgatc gggaacttgg ctttttagcg gtacatggat
    65161 tcttgcatat caacgggtat gaccatatga caccagaaga tgagaaagaa atgtttggtt
    65221 tacagaaaga gatcttggat gcctatggac tcaaaagata aaaacgtaga gaaaaacaaa
    65281 catttcctga tgtctgtgga atttgctgtc caaggagtca aaaccgtttt tgaggaagaa
    65341 cgcaatatga ggaaacatgt tgcgttcggt atccttgctt tatttatggg cgtgattttc
    65401 cagcttgatc ggatagagtg gttatggctg cttttagctg tttttctcgt ttggatagta
    65461 gagatcatca atactgtttt tgaaaatgta gtggacatgt ttacggattt tcattttcat
    65521 ccgattggga aaaaaatcaa agatatggca gctggagcag ttttagtgac cgcttgtttt
    65581 gctgtcatca ttgggttgat tttatttgtc cctaaaatat atcatttgtt gtttaattaa
    65641 aaaggagaac gtatatgcca gaacataaat cagggtttgt cgcaatcgtc ggccgcccga
    65701 atgtaggaaa atccacatta ttgaaccgaa tcgtgggtca aaaaattgcc attatgagtg
    65761 acaaggcaca gacaactaga aataaaatcc aaggagtata tactacacca gaagctcagc
    65821 tgatttttat cgatacacca ggaatccata aaccaaagca tcgtctagga gattttatgg
    65881 tagaagcagc ttacagtgcg ttgaaagaag tggatgcagt cttatttatg atcagtgctg
    65941 atcaaaaacg tggccgggga gacgatttta ttattgaacg tctaaaaaac gtgcattctc
    66001 ctgtttatct gattatcaat aaaatcgata agatccatcc agacgagttg ctgggaatca
    66061 tcgaagatta ttcgacgcag atgccttttg cacaagtgat tccgatctct gctacagaag
    66121 gaaacaatgt cgaacgctta atggatgtat tagtcagtga aatgccagag ggcccacaat
    66181 attttccaga tgatcaagtg actgatcatc ctgaatactt catcgtttct gaattgatcc
    66241 gtgagaaagt cttgttttta acacgagacg aagtgcctca ttctgtcgca gtcgttgttg
    66301 attcgatgaa gcgaaacgag aatgataaaa tccatatcca ggccacgatc atcgtcgaaa
    66361 gagatagcca aaaaggaatc attatcggca aaggcggaaa aatgctgaag caagtaggaa
    66421 cgaaagcaag aaaggatatc gaaaatcttt taggagacaa agtatttcta gaactttggg
    66481 tcaaagtcca aaaagactgg cgagacaaaa aagtctatct gcaagacttc ggctaccgaa
    66541 aagacgagta ctgatattct ggacttctta taggttaggt atagaaataa actggataaa
    66601 aatccgtacg ttgagaaaaa cagcggaaga tcgaaacata aataatctgg atcggcagaa
    66661 tctgcttttc cagatttatt ttttaggagg gagaatatga gccagcttgc agaatcgaaa
    66721 ggcttgattt tatctagccg taattacaaa gaaaaagata aattagtcaa aatctttacg
    66781 gaatcttctg gcaaaatgat gttttatatc aaaggaatcc atcggcaaaa tcagccatta
    66841 gctccggctt tgctcccctt taccgaagca gtctatatcg gtaattttcg aagtgaaggt
    66901 ttgtcgtttt taagcagtgt caaagacgtc catgcgtttc ggaacatcca agaagatatc
    66961 tttttgagcg gttatggtac gtatttgcta aatctagtag atgcagcaat cgaagatcat
    67021 caatatgacc cgcatttatt ccaatttacg caacaagctc tgcagcggat ggaccaagga
    67081 gatgatgcag aaatcatcac gaatatcttt gaagtgcaaa tactgcaacg cttcggaatc
    67141 gcgccaattt ggacgcactg tgtcgtatgc ggggaaacaa aaggaaaatt tgactattct
    67201 tccaaatatg gcggtgtgat atgcgagaaa cactggccaa tggacgaaca ccgttatcat
    67261 gcagatcctc gcgctgttta tttcgttcga atgttttcgg ctatttctta tgataagatc
    67321 agtggaatcc acttgaaaga agaaacgaag caggcaatcc gtgacctcat tgaccagttg
    67381 tatgatgaat atgtcggtat tcatctaaaa agcaaaaagt tcattgatca aatgaagtct
    67441 tgggcacacg tattaaagac gccagagaaa aatatgcctg aaaaagagat acctgaaaaa
    67501 gaagaataaa tgaaagatac aacaaaaaaa tcaaaactat ttgacaaata cagggacttc
    67561 cgtctattat taaccgtaga ttaaatagat cgttcactga gaggatctat tatacaaacc
    67621 agaaaactgc aaaatgaata cgtacattga ccaagatcag taaaaaacac gtggtttagc
    67681 gagttcggga gagtggaagc cggacccaaa cgatttttga agaggcactt gcgagtacga
    67741 taaatgaagc tgccgaatct ttattcggaa gtagggtgga accgcgaaat tattcgtccc
    67801 tatgtctgta atcagacata gggacttttt gtcgttttct ttcctgtatt cttattgaca
    67861 gcaacgctta aaaattgaaa ggggcaaaac agatgagtaa aaaattgacc gtccaagata
    67921 tgattttaac attacaaaaa ttttggtcat caaacggctg catgctgatg caagcttatg
    67981 atacagaaaa aggagcaggt acgatgagcc catatacatt cttacgggca atcggaccgg
    68041 aaccatggaa tgctgcttat gtagagccat cccgccgacc agctgacggg cgttatggag
    68101 aaaacccaaa ccgtttgtat cagcatcatc aatttcaagt cgtaatgaaa ccttcacctg
    68161 aaaatatcca agagctttat ttagaaagct tgcgtctttt aggaattgat ccattagaac
    68221 acgatattcg ctttgttgaa gacaactggg agaacccatc gatgggttgt gccggtgtgg
    68281 gctgggaagt atggcttgat gggatggaga tcacacaatt cacatacttc cagcaagtcg
    68341 gaggactacc ttgtaaacca gttacttctg agatcactta tggactagaa cgtcttgctt
    68401 cttatatcca agaagttgaa agtgtttatg atctggaatg ggctgatggc gtgaaatatg
    68461 gtgagatctt caaacaacca gaatatgaac attctaaata ttcttttgaa gtaagcgacc
    68521 aagacctgct actaagcaat tttgatcgtt ttgaaaaaga agctaaacgc tgtatcgatg
    68581 aaaatcttgt tcatccagcg tatgattata ttttgaaatg tagccataca ttcaatttat
    68641 tagatgctcg cggtgcagta tccgtaacag agcgtgcagg ttatctttcc cgtatccgca
    68701 acatggctcg tgctgtagcc aaaatctttg tggcagaacg cgaaaaatta ggattccctt
    68761 tattgaataa aaacacagca aatccagaaa acgtgaagga ggctgaataa gatggcaaaa
    68821 gacttattac ttgaaatcgg gctggaagaa atacctgctc atgtagtcac accaagcatg
    68881 aaacaattag aagaaaaaac agcaaaattt ttagatgaaa accaattgac ttatgatacg
    68941 atcgaaacgt tttctacacc gcgccgctta gcaatcaaag taacaaacat tccagaacgt
    69001 caagcagaca gcgaagaaga agtcaaagga ccagccaaaa aaattgcttt ggacgcagat
    69061 ggaaactgga cgaaagcagc tgaaggattt gtccgcggac aaggtctgac gacagatgct
    69121 atcactttta gagaattaaa aggcgtggaa tatgtctatg taacgaaata cactcacggc
    69181 aaagaagcaa aagaagtatt gacaggttta gcagatgtca ttaaaagcct cactttccca
    69241 gtaacgatgc actgggcaga atacgatttt gaatatattc gccctattca ctggatcgtg
    69301 gcattgttag atgacgaaat aatcccgttt gagatcttgg atgtcaaaac agacagagct
    69361 tcaagaggtc atcgtttctt aggcgaagat gtgacattta cgcatgcaaa acaatacgaa
    69421 gaaaaattga atgaacaatt tgttattgct tcaccgcaaa aaagaaaaga aatgatcatc
    69481 acacaagcaa acgaattagc agaaaaaaat cactggatca ttgatctaga tgaagattta
    69541 ctagaagaag tcaacaattt agtcgaatat ccaactgtct tttctggcga cttcgaagaa
    69601 aaatatctat ctgttcctga agaagtacta gtcacttcta tgaaagaaca tcaacgttat
    69661 ttcgaagtac ggaacgatca aggtatgttg cttcctcatt ttatttctgc tcgtaatggc
    69721 gatcgggtaa aattggaaaa tgtggtacga ggcaatcaaa aagtattgac tgctcgttta
    69781 gaagatgcgg aattctttta taatgaagac aagaaagctt caatcgacca atacgttgaa
    69841 aaattaaaaa ctgttacttt ccatgaaaaa atcggtagca tctatgagaa aatgcaacgg
    69901 gtacaagtca tcgctcgcat cataggcgaa caagtaggac tatctgagga agaattgatg
    69961 gatctgcaac gcgctgctga aatctataaa tttgatctag taaccaacat ggtaggagaa
    70021 ttccctgaac tacaagggat catgggcgaa aaatatgctc tgcttaaagg cgagaaacca
    70081 gccgtagcaa cagcgatccg tgaacattac atgcctatat ccagtgaagg agatttacct
    70141 gagactacag taggttctgt tttagcgatt gctgataaat tagatagtat cttttctttc
    70201 tttgcagttg ggatgatccc aagtggctca aacgatccat atgctttgcg ccgtcaagca
    70261 tatggtgtcg ttcgaatcat cgaatcgaaa aaatgggcct ttcctttgtc tgttctgcaa
    70321 gaaacgatta gtgaagttat cagtaaagat acggatcgtt ttggcattgg cttgtcagcg
    70381 ggacaacaac aggtgatcga ctttatcaaa ggccgtctgc gccaattatt gacaacgaag
    70441 aatatccgtc atgatgtcat cgaagctgtt ttgaatgcag aacaaaaaga tctgacaaaa
    70501 gtatttgcag cagcacaatt gttcaagcag catcttgcag atgaagactt caaaccatcg
    70561 atggaagctt tgacacgtgt cgtgaactta gcgaaaaaag cggagcttga aaaacaatca
    70621 gaagtagacc ctgaactgtt cgaaaacgaa gcggagaaag aactgcacaa agcagtagag
    70681 gcaatgaaaa caagctttgc tgaccaaacg atcaacgaaa attatgatca gcttgtaagc
    70741 cttcgcccac tgatcgaaaa ttattttgat cagacgatgg tcatggcaga agaaccagca
    70801 gtacgtaaga accgattaac gcaattaagt caaattgctg ccatggcttt gtcactagca
    70861 agtttagatc aaatcatcac aaaataattt ctaatatgta aataaaccag agaacaggca
    70921 caaaataggc tatttctctg gtttatttgt tataaatata aataactatt attaattcaa
    70981 tgttaatttt tttgttattt tattttttgt gtaactttta aaaacaccta tgaaaattaa
    71041 ggaaataaaa atgaaatcga ttaattgtta tcttattaat gttttattta cttttaaatc
    71101 gtaaattgcc
//
LOCUS       DAZULR010000011        65550 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.011, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000011 DAZULR010000000
VERSION     DAZULR010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 65550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65550
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.011"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            203..721
                     /locus_tag="ACG8ZV_000786"
     CDS             203..721
                     /locus_tag="ACG8ZV_000786"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFS4996149.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            849..1532
                     /locus_tag="ACG8ZV_000787"
     CDS             849..1532
                     /locus_tag="ACG8ZV_000787"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HFS4996150.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1841..1914
                     /locus_tag="ACG8ZV_000788"
     tRNA            1841..1914
                     /locus_tag="ACG8ZV_000788"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1875..1877,aa:Arg,seq:tct)
     gene            2073..2432
                     /locus_tag="ACG8ZV_000789"
     CDS             2073..2432
                     /locus_tag="ACG8ZV_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HFS4996151.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            2555..4186
                     /locus_tag="ACG8ZV_000790"
     CDS             2555..4186
                     /locus_tag="ACG8ZV_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015103 - inorganic anion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HFS4996152.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(4248..4889)
                     /locus_tag="ACG8ZV_000791"
     CDS             complement(4248..4889)
                     /locus_tag="ACG8ZV_000791"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HFS4996153.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    5075..5151
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            5171..5479
                     /gene="rplU"
                     /locus_tag="ACG8ZV_000792"
     CDS             5171..5479
                     /gene="rplU"
                     /locus_tag="ACG8ZV_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HFS4996154.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            5506..5850
                     /locus_tag="ACG8ZV_000793"
     CDS             5506..5850
                     /locus_tag="ACG8ZV_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HFS4996155.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            5863..6156
                     /gene="rpmA"
                     /locus_tag="ACG8ZV_000794"
     CDS             5863..6156
                     /gene="rpmA"
                     /locus_tag="ACG8ZV_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HFS4996156.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            6590..9397
                     /locus_tag="ACG8ZV_000795"
     CDS             6590..9397
                     /locus_tag="ACG8ZV_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFS4996157.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            9588..10079
                     /locus_tag="ACG8ZV_000796"
     CDS             9588..10079
                     /locus_tag="ACG8ZV_000796"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose/fructose/sorbose PTS transporter subunit
                     IIB"
                     /protein_id="HFS4996158.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            10182..11171
                     /locus_tag="ACG8ZV_000797"
     CDS             10182..11171
                     /locus_tag="ACG8ZV_000797"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose/fructose/sorbose PTS transporter subunit
                     IIB"
                     /protein_id="HFS4996159.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            11204..12007
                     /locus_tag="ACG8ZV_000798"
     CDS             11204..12007
                     /locus_tag="ACG8ZV_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HFS4996160.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            12028..12942
                     /locus_tag="ACG8ZV_000799"
     CDS             12028..12942
                     /locus_tag="ACG8ZV_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFS4996161.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            13025..13399
                     /locus_tag="ACG8ZV_000800"
     CDS             13025..13399
                     /locus_tag="ACG8ZV_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HFS4996162.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            13538..13783
                     /locus_tag="ACG8ZV_000801"
     CDS             13538..13783
                     /locus_tag="ACG8ZV_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFS4996163.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            13955..15019
                     /locus_tag="ACG8ZV_000802"
     CDS             13955..15019
                     /locus_tag="ACG8ZV_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HFS4996164.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            15265..15690
                     /locus_tag="ACG8ZV_000803"
     CDS             15265..15690
                     /locus_tag="ACG8ZV_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFS4996165.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            15683..16132
                     /gene="nusB"
                     /locus_tag="ACG8ZV_000804"
     CDS             15683..16132
                     /gene="nusB"
                     /locus_tag="ACG8ZV_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HFS4996166.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            16229..17083
                     /locus_tag="ACG8ZV_000805"
     CDS             16229..17083
                     /locus_tag="ACG8ZV_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HFS4996167.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            17084..18421
                     /gene="xseA"
                     /locus_tag="ACG8ZV_000806"
     CDS             17084..18421
                     /gene="xseA"
                     /locus_tag="ACG8ZV_000806"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HFS4996168.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            18426..18650
                     /locus_tag="ACG8ZV_000807"
     CDS             18426..18650
                     /locus_tag="ACG8ZV_000807"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HFS4996169.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            18652..19542
                     /locus_tag="ACG8ZV_000808"
     CDS             18652..19542
                     /locus_tag="ACG8ZV_000808"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HFS4996170.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            19551..20369
                     /locus_tag="ACG8ZV_000809"
     CDS             19551..20369
                     /locus_tag="ACG8ZV_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HFS4996171.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            20476..20925
                     /locus_tag="ACG8ZV_000810"
     CDS             20476..20925
                     /locus_tag="ACG8ZV_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFS4996172.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            20943..22625
                     /gene="recN"
                     /locus_tag="ACG8ZV_000811"
     CDS             20943..22625
                     /gene="recN"
                     /locus_tag="ACG8ZV_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HFS4996173.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(22680..22796)
                     /locus_tag="ACG8ZV_000812"
     CDS             complement(22680..22796)
                     /locus_tag="ACG8ZV_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HFS4996174.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(22869..23825)
                     /locus_tag="ACG8ZV_000813"
     CDS             complement(22869..23825)
                     /locus_tag="ACG8ZV_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFS4996175.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            23996..24364
                     /locus_tag="ACG8ZV_000814"
     CDS             23996..24364
                     /locus_tag="ACG8ZV_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HFS4996176.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            24534..24965
                     /gene="mraZ"
                     /locus_tag="ACG8ZV_000815"
     CDS             24534..24965
                     /gene="mraZ"
                     /locus_tag="ACG8ZV_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HFS4996177.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            24986..25945
                     /gene="rsmH"
                     /locus_tag="ACG8ZV_000816"
     CDS             24986..25945
                     /gene="rsmH"
                     /locus_tag="ACG8ZV_000816"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HFS4996178.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLRQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            25950..26351
                     /gene="ftsL"
                     /locus_tag="ACG8ZV_000817"
     CDS             25950..26351
                     /gene="ftsL"
                     /locus_tag="ACG8ZV_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HFS4996179.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            26352..28544
                     /locus_tag="ACG8ZV_000818"
     CDS             26352..28544
                     /locus_tag="ACG8ZV_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HFS4996180.1"
                     /translation="MSLKNKIWRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKTGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            28570..29532
                     /gene="mraY"
                     /locus_tag="ACG8ZV_000819"
     CDS             28570..29532
                     /gene="mraY"
                     /locus_tag="ACG8ZV_000819"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HFS4996181.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            29546..30907
                     /gene="murD"
                     /locus_tag="ACG8ZV_000820"
     CDS             29546..30907
                     /gene="murD"
                     /locus_tag="ACG8ZV_000820"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HFS4996182.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            30933..32021
                     /gene="murG"
                     /locus_tag="ACG8ZV_000821"
     CDS             30933..32021
                     /gene="murG"
                     /locus_tag="ACG8ZV_000821"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HFS4996183.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            32036..33256
                     /locus_tag="ACG8ZV_000822"
     CDS             32036..33256
                     /locus_tag="ACG8ZV_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HFS4996184.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            33412..34737
                     /gene="ftsA"
                     /locus_tag="ACG8ZV_000823"
     CDS             33412..34737
                     /gene="ftsA"
                     /locus_tag="ACG8ZV_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HFS4996185.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            34760..36001
                     /gene="ftsZ"
                     /locus_tag="ACG8ZV_000824"
     CDS             34760..36001
                     /gene="ftsZ"
                     /locus_tag="ACG8ZV_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HFS4996186.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            36018..36695
                     /locus_tag="ACG8ZV_000825"
     CDS             36018..36695
                     /locus_tag="ACG8ZV_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HFS4996187.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            36709..37308
                     /locus_tag="ACG8ZV_000826"
     CDS             36709..37308
                     /locus_tag="ACG8ZV_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HFS4996188.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            37389..37610
                     /locus_tag="ACG8ZV_000827"
     CDS             37389..37610
                     /locus_tag="ACG8ZV_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HFS4996189.1"
                     /translation="MVYALLSWFPGGYQSGLGRLLAKICEPYISLFDRLPLRIGPLDF
                     TILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            37659..38441
                     /locus_tag="ACG8ZV_000828"
     CDS             37659..38441
                     /locus_tag="ACG8ZV_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HFS4996190.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            38462..39169
                     /locus_tag="ACG8ZV_000829"
     CDS             38462..39169
                     /locus_tag="ACG8ZV_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HFS4996191.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            39431..42229
                     /gene="ileS"
                     /locus_tag="ACG8ZV_000830"
     CDS             39431..42229
                     /gene="ileS"
                     /locus_tag="ACG8ZV_000830"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HFS4996192.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKSYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(42278..43804)
                     /gene="zwf"
                     /locus_tag="ACG8ZV_000831"
     CDS             complement(42278..43804)
                     /gene="zwf"
                     /locus_tag="ACG8ZV_000831"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HFS4996193.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(43819..44466)
                     /locus_tag="ACG8ZV_000832"
     CDS             complement(43819..44466)
                     /locus_tag="ACG8ZV_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HFS4996194.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(44650..44979)
                     /locus_tag="ACG8ZV_000833"
     CDS             complement(44650..44979)
                     /locus_tag="ACG8ZV_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HFS4996195.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            45156..45884
                     /gene="sfsA"
                     /locus_tag="ACG8ZV_000834"
     CDS             45156..45884
                     /gene="sfsA"
                     /locus_tag="ACG8ZV_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HFS4996196.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            45900..46913
                     /locus_tag="ACG8ZV_000835"
     CDS             45900..46913
                     /locus_tag="ACG8ZV_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFS4996197.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            46913..48190
                     /locus_tag="ACG8ZV_000836"
     CDS             46913..48190
                     /locus_tag="ACG8ZV_000836"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFS4996198.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            48253..50955
                     /locus_tag="ACG8ZV_000837"
     CDS             48253..50955
                     /locus_tag="ACG8ZV_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFS4996199.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            51107..51424
                     /locus_tag="ACG8ZV_000838"
     CDS             51107..51424
                     /locus_tag="ACG8ZV_000838"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFS4996200.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            51454..51774
                     /locus_tag="ACG8ZV_000839"
     CDS             51454..51774
                     /locus_tag="ACG8ZV_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFS4996201.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            51882..53342
                     /locus_tag="ACG8ZV_000840"
     CDS             51882..53342
                     /locus_tag="ACG8ZV_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFS4996202.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGPNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            53410..53631
                     /locus_tag="ACG8ZV_000841"
     CDS             53410..53631
                     /locus_tag="ACG8ZV_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996203.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            53662..53844
                     /locus_tag="ACG8ZV_000842"
     CDS             53662..53844
                     /locus_tag="ACG8ZV_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HFS4996204.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            53844..54257
                     /locus_tag="ACG8ZV_000843"
     CDS             53844..54257
                     /locus_tag="ACG8ZV_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HFS4996205.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            54380..55561
                     /locus_tag="ACG8ZV_000844"
     CDS             54380..55561
                     /locus_tag="ACG8ZV_000844"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4996206.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(55632..55796)
                     /locus_tag="ACG8ZV_000845"
     CDS             complement(55632..55796)
                     /locus_tag="ACG8ZV_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996207.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            55950..56023
                     /locus_tag="ACG8ZV_000846"
     tRNA            55950..56023
                     /locus_tag="ACG8ZV_000846"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:55984..55986,aa:Arg,seq:cct)
     gene            complement(56092..57231)
                     /locus_tag="ACG8ZV_000847"
     CDS             complement(56092..57231)
                     /locus_tag="ACG8ZV_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4996208.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            57403..57537
                     /locus_tag="ACG8ZV_000848"
     CDS             57403..57537
                     /locus_tag="ACG8ZV_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996209.1"
                     /translation="MIKVIFKRITELPEFRLFVDYWYVWFFIVALLIGLDVILERKLK
                     "
     gene            complement(57530..58165)
                     /locus_tag="ACG8ZV_000849"
     CDS             complement(57530..58165)
                     /locus_tag="ACG8ZV_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996210.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINNASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(58278..58913)
                     /locus_tag="ACG8ZV_000850"
     CDS             complement(58278..58913)
                     /locus_tag="ACG8ZV_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HFS4996211.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(58947..59408)
                     /locus_tag="ACG8ZV_000851"
     CDS             complement(58947..59408)
                     /locus_tag="ACG8ZV_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4429 domain-containing protein"
                     /protein_id="HFS4996212.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            complement(59538..59969)
                     /locus_tag="ACG8ZV_000852"
     CDS             complement(59538..59969)
                     /locus_tag="ACG8ZV_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HFS4996213.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(59987..60307)
                     /locus_tag="ACG8ZV_000853"
     CDS             complement(59987..60307)
                     /locus_tag="ACG8ZV_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFS4996214.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            60606..61382
                     /locus_tag="ACG8ZV_000854"
     CDS             60606..61382
                     /locus_tag="ACG8ZV_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HFS4996215.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            61397..61600
                     /locus_tag="ACG8ZV_000855"
     CDS             61397..61600
                     /locus_tag="ACG8ZV_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4996216.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            61616..61936
                     /locus_tag="ACG8ZV_000856"
     CDS             61616..61936
                     /locus_tag="ACG8ZV_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HFS4996217.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRR"
     gene            61941..62111
                     /locus_tag="ACG8ZV_000857"
     CDS             61941..62111
                     /locus_tag="ACG8ZV_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996218.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEYRAKKPVGRD"
     gene            complement(62118..62900)
                     /locus_tag="ACG8ZV_000858"
     CDS             complement(62118..62900)
                     /locus_tag="ACG8ZV_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996219.1"
                     /translation="MDISDTPYYQKLIASSKLIGETIAPSLDVVNAMQPAIEQAKKLI
                     AIQDTFIASQAILNDSLIQIVEKRNKSIANMIPPSLFAIQKQLESPSFNIAKKMAATM
                     PKPYFSDISKITEKFAVDMSKYDFRIGVATQELEKAFSSEPEVSTKNLLFKDTSNPSD
                     EFEAKFFDILNEQRKVLDDSIKLFEEINTAKNKDITNEPSEKQQASPAFYKDKMWYLE
                     QTGAALIGLVVTEIVNITIGVDPNNTISLALFLRYLLQFLIN"
     gene            62966..63658
                     /locus_tag="ACG8ZV_000859"
     CDS             62966..63658
                     /locus_tag="ACG8ZV_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HFS4996220.1"
                     /translation="MLKNKEAVTTSLQVAETFRKEHRAVLKAIDDLKDGLAQKYADLF
                     WEDVYIHPQNKQAYRIVYMNRDGFTLAVLGFNNTQKVLEFKLKYIEAFNEMEKAIRKN
                     TAFDTIEDMMIYQLEEMKDVKKDVSMLKNTMRISGQQEFEIKQKGNTKVMEVLGGKES
                     RAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEIDQL
                     NRQQRLFGDENE"
     gene            63836..64177
                     /locus_tag="ACG8ZV_000860"
     CDS             63836..64177
                     /locus_tag="ACG8ZV_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996221.1"
                     /translation="MEKELSTLDQYLTDPSWGKSNIKETNNRKIRRNLLTDEELACDQ
                     DDLGNFVSIWDHVYLIHLSRKSKKPEYIYVIEDGLIDALEEYDRDNLIDISYYGSGKK
                     YIAEMEAEFDE"
     gene            64170..64841
                     /locus_tag="ACG8ZV_000861"
     CDS             64170..64841
                     /locus_tag="ACG8ZV_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HFS4996222.1"
                     /translation="MSENKGTTTFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            64847..65533
                     /locus_tag="ACG8ZV_000862"
     CDS             64847..65533
                     /locus_tag="ACG8ZV_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative HNHc nuclease"
                     /protein_id="HFS4996223.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDIGATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     ETIKKLRIGG"
BASE COUNT        21743 a        10985 c        13704 g        19118 t
ORIGIN      
        1 cctttctaaa acttgtaatg ttagggtaaa cgttttttaa actaacgtca attatttata
       61 ataaaaaatg agataaagat gaggaaatag aattagaaac atataattat taaagggaaa
      121 catttttaca gctataattt gaaaaaaatt tatcgttatt atatgattaa gaaggattga
      181 ataaagaaag aagttgaaaa cgatacctga ttacaaaaaa ataactttta taagttctat
      241 aacgttgatt atatttttaa ttcttattct tctcgtcgtc ttggttcccc gaatttttgg
      301 tttgactcct tatattattg aggacaaaga aatgagtcca tattatgcac aaggaaatct
      361 gatatatgta cgaccgaaaa atacaaatga gattttagtc ggagatatta ttacatatta
      421 tgaaaattca ggaaaaaaaa tctcgacgcg tcgcgtaata gccgttgaaa acaaccacga
      481 agatttttat acaaaagctg atacaaagac ttatattgag cctggagtag taaaaaagag
      541 aaatattatc ggtagtccca tctttcagat tccatatatt ggactagtcc tttcaaaaac
      601 ggcatttgca tggattcagg ggttattctt tacgattgct ttttgcctaa caggaatcac
      661 agcatggaat acctttgtag agttgaaaaa gaagcggaga cgaacacaga aatttttgta
      721 agaatgttaa aaacataaat gtattccaga gatccaacga ctcttctgaa catgaaacac
      781 gagaaaacac tcatgcagct tgtagattta gtcagttgtt cgtataatgt gtgaagagga
      841 ggagtagtat gcgcaatgaa atgatgcatc gtcctgtagt caaagaagaa ctattggatt
      901 ttatgcgtac ccagcaaaaa aaattaccgg gtgagctagg caaactggaa gaagaagctc
      961 atgtagcaga agtaccagtt attccccatg aaacagttgt atttttgaaa tttttacttg
     1021 gacagcttca gcctgaacga atcttggaga tcggagcagc tatcggtttt tcatcaagtg
     1081 tcatggccac gacaatcgga gaaaacgctc atgttacgac aattgatcgt ttcgatgtca
     1141 tgatcgagaa agctaaaaaa aactatgaac gtctaggact gacagataaa gtgactttgc
     1201 ttgaaggtca agcagcagat atcttgccgg agttgtctgg tccgtatgac tttattttta
     1261 tggatagtgc aaaatcaaaa tatattgaat ttttacctga atgcttacgt ttgttaagaa
     1321 aaggtggcgt tttgatggta gatgacatct tccaaggagg aacgatcttg ctcccagatg
     1381 aagagattcc ccgtggcaaa cgagctatcc atcgtaaatt aaatgaattt cttcgtgttg
     1441 tgatggatca tcccgatttg acatcgacaa tcttgccatt aggtgatggt gtgatcttaa
     1501 tgacaaagga atcagaaaca atcgagttgt gatacatgat tatggcagcc tgtagataat
     1561 cgattgaatc gagggctcaa ttcgaacttg atgtaaaagt ttctatattt gtaagtcaat
     1621 taaaggatac aggaaatcta aataaacagg agtagcatga agtcaatgta gctcctgttt
     1681 tcaattgata accttagaac agctgaagga gaatgtctcg ttttaaaaga ttgatttagt
     1741 agttgggcca aaataattca ttatttgcta attaaataac tatttcgtat tgacagaagc
     1801 aatttaatta tctataatta ttgatgttcc gctgattctt gtcatagtag ctcagctgga
     1861 tagagcatcc gccttctaag cggacggtcg ggggttcgaa tccctcctgt gacgctaaaa
     1921 aaccgttaga aactgaggtt tctaacggtt tttctttgtt ttttgtgcca atattgtttg
     1981 ttttcaaagg caaataaaat aaaaaaacat ccttatcgag tacaattata aggagcaaaa
     2041 aaataaaact catcagaaaa gaggaagaag atatgacgat actatctaga attttagtga
     2101 ctctagttgc aattgaattt ttttatatca tgtatatcga aacggtgaga actgattctg
     2161 acacgacaag tagggttttt aaaatgagta aagaagagtt aagcagaaaa tctgttcaaa
     2221 cattgtttaa gaaccaagga gtgtacaatg gactattagg agtgggacta ctttatggag
     2281 cttatctttc ttccgcatct aaagaaatca caagtatgct attaatatct attttttttg
     2341 ttgcattata tggcagtttg actagcgatc gttggatttt actcaaacaa ggtgggctag
     2401 ctctgttggc attgctttct attttcttat aaatatagaa aaaataagaa tttatctaac
     2461 aggaaacttt gtgaaaaata ttactttatc tcatgaaata tgatattcta atgaatggta
     2521 ttttagaaaa tttcatgaaa aaggagttag ataggtgttc aaaaattatg tttcctcact
     2581 aaaaaaagaa ttttcaggtt atgatctttc aagatttcag aaagatcttt tggctgggat
     2641 cacagtagct gctgtagcat tgcctttagc cttggctttt ggggtatcaa gcggagctga
     2701 tgcggccgca ggtttgatta cggctatcat tgccggtatc gttattggcg gtttatcagg
     2761 cggtttttat caaatatcag gtccgacagg tgcgatggca gctatcttga tgtctattgc
     2821 ggcaacaaag ggaatgcaag gtgtattgct tgctactttt ttagcgggtc tatttttact
     2881 tgcagcagga cttttccgat taggaacact gacttctttt atcccagcac ccgtaattac
     2941 ggggtttact tcaggtattg ctatcattat tgcattaggt cagatcgata atttatttgg
     3001 tgttcactcg gaaggtacaa acgttattga aaaactaagt agttatcaaa cgataggatt
     3061 tccgataaac acagcctctt tgatcatggg agggctagtc attttaggga tgtttatcta
     3121 tccaaaaaaa tgggcgaaac gaatgcctag ttcgctgctg gctatcattt tggcaacagc
     3181 agttatgcta ttgttccatt taccagtagc aactgtgggt aagattccac aaacattgat
     3241 cagtagtaat cgtttgaata tgggagattt tagcttttct gccttgcaac aagtggcagt
     3301 tccagctatt agcattgctt tattaggaat gattgaaagc ttgctatgtg gtgcttcggc
     3361 tggccgaatg gcaaataagc ccttagatag caatcaagaa ttaatggcgc aaggaattgg
     3421 aaatctgttg cttcctttct ttggcgggat tcctgctact gcggccatcg cccgtacaag
     3481 cgtggccatc aaatctggtg cacaaactag attagctggt atgatacatg cagttgtctt
     3541 actgctctcc atgcttgttt ttgcgccagt gatgtcacag attccaatgc cagcacttgc
     3601 aggtgttttg attgtgacgg cttggcgtat gaatgaatgg gaaacgatca aggagctatt
     3661 tactaataaa tattggtcag cagttctatt gtttatcctt acgatgattt gtacagttat
     3721 ctttgattta agtattgcta tcgtgatcgg ggtgatcggc ggctgtgtat tttttgttgt
     3781 caaaagcgct gctatcacga tttcattaga aacgatcgat tggcaaagaa tggggctgcc
     3841 agaaacggaa aagctgaata actggacagt agtgtatatt agtggtccac tgttttttat
     3901 gtcttcagaa aaactcaaaa ataaattgga agaactaaat catcacgatg gtgtcatttt
     3961 ctccatgcga ggcgtaccaa gtattgattt gacggcacgt gcagtttttg atgaatttca
     4021 agaaaaagca gagcaaagag gacaaacgat tatctatact tccttgcagc cagaagtaga
     4081 aaaacaactt tctcacttgt gggaacatac attcacgcat caacatcaaa cagttgctca
     4141 tgcgttgaca gctttacatg cgaaatatac tgcaattagc cattaaaaca atgaaaaaga
     4201 acagacaaga ctgtaaactg aagattttat ggtcttgtct gttcttttta atattgctgt
     4261 aaaagtgaag ctagtacttg ccagtcttga tggataacag gtacaaggga gcgattgtag
     4321 aaaatagctg ctggatgaaa aagtggaaga attcgatagt ttttttctga ccattcgtag
     4381 gcatcctttt gttctgttaa ttgtaagaca ggccctgtat agagttgacc atgatttttg
     4441 gtaaccgtat attctttgcc aagtaaacgt tgaagaccaa tgtttccaag tgtcgcaatt
     4501 aattttggct ggaccttcat cagttcgtaa tccaatattg gtgcatgcgc aaatacttcg
     4561 gaacgagtag gtgtccgatt tggataaaca gtttctgact gttgtgtccg tttattgatc
     4621 cgatgagtca cgcgatacgg gcggctcctt acagcactgg tgatatacac ctcttctcgt
     4681 gttaagccag ttgaagaaag tgcctgcatc aattcttttc cagcttgacc gctaaaagga
     4741 acatgcgtat caatctctgt tttccctggg gcttctccca cgagcatcag tttaggatga
     4801 agaggtcctt gcccagcgat aaatccttct acaggacggc cgttcattct taaagaagct
     4861 tcttgtatca gttcttttgg gtattccatt tatgctcctc ctttttcttt tattataaga
     4921 ataaaagaaa cacaatgcga ctattttatt tggtagaact gtgaggatag aaaagcagaa
     4981 gtattgcttg aatttttgtt ttactttttg attttaaatt tagttgacta acggttgctg
     5041 ttctggtaag ctagtactgt tgtaattgtg gactccacag ctacaaccgc tcagaacaag
     5101 taataagcac agcatatgct gtcacttcgg atggcgagtc taagtatatc agaaggaggt
     5161 gctttatagc atgtacgcaa ttattaaaac tggtggtaaa caagtaaaag ttgaagtggg
     5221 acaagcaatc tatgttgaaa aacttgacgt tgaagcagga gaaaaagttg tttttgacga
     5281 agttatctta gtaggcggag aatctacaaa agtaggcgct ccaactgttg caggtgcaac
     5341 tgttgaaggt actgttgaaa aacacggcaa acaaaagaaa gtcgttactt tcaaatacaa
     5401 acctaaaaaa cattcacacc gtaaacaagg tcatcgtcaa ccatatacaa aagtggttat
     5461 cgacgcgatc aacgcttaat agcgtttgag aaagaaggcc tatatatgat caaaggaaca
     5521 tttaagcgaa atgacgcagg tcagatcgtt tcattcactt tgaccgggca tgctgatgct
     5581 ggtccttatg gaagtgatat cgtttgtgcg ggtgtttctg cgttagcgat cagcactgtc
     5641 aacgggattg cctcattagc cggttttgag ccgattgttg aaatgaatga agaagaaggc
     5701 ggttatcttt ataccgaagt cacttcagga atgacacaag aacaaaacaa tattgctgag
     5761 attctattag aaaatctttt attaggatta caatcgatag aagctgaaaa ctcagaatat
     5821 atccaaatta aaacaattaa tgataaatag gaggtgcaga ccatgttgtt atctatgaat
     5881 ctacaattat ttgcccacaa aaaaggtggc ggttctacat ctaacggccg tgactcagaa
     5941 tcaaaacgtc taggtgctaa acgtgctgat ggacaaacag ttacaggtgg atcaattctt
     6001 taccgtcaac gcggtacaaa aatctatcca ggtgtaaacg tgggtatcgg tggagacgac
     6061 actttatttg caaaagttga tggcgtagta cgtttcgaac gtaaaggccg taacaaaaaa
     6121 caagtgtctg tttatccagt agctcaagaa gcttaattga atcttatgat taaagaggtt
     6181 gtgacaagac ttttgtcaca gccttttttg tttataaaaa taaaagttgt agtggaggct
     6241 acgaagttta ctttgtcttt ttacacttaa tatttttttg ccaatttgga atcaggatgt
     6301 tttgataact atcgttttca attgatggaa gctatattgt ttgctatcag tgaaataatt
     6361 atatggtaaa cagtgttctt tttcttgttt ccattataaa aatcgtatcg ggatttttcg
     6421 ttcttttaaa ttgaacattt ctatctatcc gcgtgttatc aacaaaacaa aatcaggtaa
     6481 atagttgacg aaacagaaat aaatacatag tattatgttt tgaagcctaa gtacaatagt
     6541 ctatagaaaa ggagcgatac cattggcaaa acgcattgac cgaatttata tgtatgtcaa
     6601 agaaaaaacc gctcatttaa caaaggcaga atatgatcaa ggagtaacaa cacaggaaat
     6661 tgctgaagtg ttagggattc agcgaacaaa tagcagtaaa gatctgaatc agctagtgcg
     6721 cgaaggaaaa ctgataaaga cagacggacg accagtacgt tacatatatc aaacactcgt
     6781 tacgcacgta aagccagtta caaaacatgt agtcagttac aaagaaacgc cggtctctga
     6841 agaaaaaaat acactccaaa tagatactaa ggatatcttt gcaaaaatca ttggagctaa
     6901 cggcagcatg aaaaattcag tggaacaggc aaaagctgcg attttgtatc cgccaagagg
     6961 attaaattgt ttgattacag gacctaccgg atcaggaaag acttattttg cacacgcgat
     7021 gtatcatttt gcaaaagcgc atcatgtaat agatgaggaa acggaactga ttgttttcaa
     7081 ttgtgctgat tatgccaata accctgagct tttgatgagt catttatttg ggtacgcaaa
     7141 aggtgctttt acaggcgcag atgaagaaaa aatggggatt atcgatcaag cggatggcgg
     7201 tatgctgttt ttggatgaga ttcaccggtt gccgcctgaa ggtcaagaaa tgatctttta
     7261 ctttatggat catggaactt acagtcgtct tggggaaaca acgaaatccc atgaagcaaa
     7321 tgtacggatc gtaggtgcga ccacagaaga cccaggttct tctctattag aaacttttgt
     7381 tcggcgtatc ccaatcaata tcaaacttcc ggcttttgaa aaacgtcctg caaatgagaa
     7441 agtcgattta gtaaaaatca tgattgccca cgaagcaaac cgcacgcagc gaaagatttc
     7501 tttgacagaa gatgtagcaa aagcattgat cggcagtgtg acctatggaa atataggaca
     7561 attgaagtca aatatccagt tagtatgtgc acgaggattt ctaaatcata tgcaatcacc
     7621 cgaaatctcg atcacaatcg atgatttgac agaagggatt cgtagcggat tgattcaatt
     7681 agcaagcaac cgcagtgcaa tggcagagct ttctaaaata ttggagccaa agataactgt
     7741 agcaccaaat gatacgatca tgaaaatcca atcggactcc tatgagttac cttataatct
     7801 atatgatatc atcggagata aagcagcttt actgaagtcg gatggtttgg atcaagaagc
     7861 aatcaatcat ttcatttcta cagatatcaa catccatctg aagtctttct ataaagacca
     7921 tggtttttct tttaatgcag acagcaaatt agcagaattt gtagatccga aaatcataga
     7981 agtgaccaat cagatttatg taatggtcaa aagatcttta ccatatgagt ttcagcaaaa
     8041 ctttatttat gctatgagct tgcatatcag ttcttttttg aaaaaaatca acttaggaga
     8101 agaacggcat acgaatgata acatccgtga gatggctttt gattttccag atgaatatgc
     8161 tgttgcgaaa gaagtgcgta gttatatcga aacgtatttt caagtggaga ttccagaaag
     8221 tgaagactat tacttgaccg ttctactcgt ctcgttacgg gcaaatcaag caagcggcag
     8281 aatcggtgta gtcgttgcag ctcacggaaa cagcacagca agcagtatgg tccaagttgt
     8341 ccaacagttg ttagatgcag agaacgtacg agcagtagac atgcctttgg atatggatcc
     8401 gaaaacagca ttggaccgaa ttgaacgcaa tgtacaagaa gtagatgaag gaagcggggt
     8461 catactctta gtagatatgg ggtcccttgc gtcgtttaat tcgcaaattc aaagagacac
     8521 tggaattcca gtacgtactg ttgatatggt aacaacttct ctagttttgg aaactgtacg
     8581 aaaggtctca gtattaggga cagatctaga tatgttgcat gaatcattga aaaattttcg
     8641 aggttacgca gaaatatctt ctgtagaatc tgttcaggaa gcaaaaccta ttcataagaa
     8701 aaaagctgtt ttggctatct gcgcatctgg cgaaggtaca gcacaaagaa tcaaagaatt
     8761 gatcgaacga gcggtaaaca agcgtcaaga aacagaatta gaagttctag ctttgtcgat
     8821 tgtggaagtg aaagaagaac tgccagttat ccaaaaagaa tatcagatca tagctactac
     8881 tgggattact gatttgaata tccaagcccc atttattcct ttagaacgtt ttattgatca
     8941 aaatatcgaa gtcattttgg atcagttgct gatggaatca gaattggagg aaactgaatt
     9001 catctcccta gatgaagagt cagctaaaaa tacgtgtgtt gagtttatct ctgataactt
     9061 catctttatt aatggtagta agttaatcga tccaatgtgg caattttcta cacaaatctc
     9121 tcagacgacg ggaatcggcg atgaagaata tggattcaaa atcaacctag tgatgcacac
     9181 agcaggaatg atcgaacgta ttattcggaa tgaaccattg actgtggaag aaaacgaatt
     9241 gacaaataca acgaatgatc ctctttatag ccaattggca gcctcagttg ttctgttgga
     9301 agatcagata aaagtaaaag tgccgataga agaaatgtat tatctgctac gtctagtcca
     9361 taatcagtta gataaaaaag aatacactgt gccatgaata cacaaaaacg atacactttt
     9421 atagtgtatc gtttttgtgt attggttaag aatcctttaa attcaattag tgtatcgtaa
     9481 aaaagttggc acgctttttg cttatagtag tgtgtgctag gaggtggttg ttcacacaga
     9541 aatgataggg gtttctgtga agtagtgagg aagaaggagt tttgcagatg gatattcgat
     9601 tggcacgtat agatgatcgt ttaatccacg ggcaagtcgc aacagtttgg tcgaagcaaa
     9661 caggtgttga acgtatcatt gtgatcagcg atgtagtcgc tcaagataaa ttgagaaagt
     9721 ttctactaaa agaagctgca ccgccgggga tcacagcaaa tgtaataacc gtgcagaaaa
     9781 tgattcaaat ctatcatagt ggattattat cacgagcaaa agtgatgctt ttattcacca
     9841 atccccaaga tgttgaagcg gttgtccgct gcggtgtaca gttgaagtcg ttgaatatcg
     9901 gcggtatgag ttttactgaa ggcaaatcaa tgattaccaa ttttgtttca gtaaatcaac
     9961 aagatattga ttcctttcgt tacttgaaca gtcaagaagt ggagttagag attcgaaaag
    10021 tacctgctga caggaaaatc cttttgatgg aactactagc gaaaatcaaa aaggtgtagc
    10081 aagaatggtt gttggaaaag gtcaaataat tctgttgtaa tggttagcaa ttattaatat
    10141 ttttgaattt gttacaacaa aagtaaatag gaggtataaa tatggtaggg attatcctag
    10201 caagtcatgg acaatttgct gaaggaatct tacaatccgg ttcaatgatc tttggcgaac
    10261 aagaaaacgt caaagccgtg attttgaaac caagtgaagg tccagatgac ttgagagcca
    10321 aattggaaga agcggttgct tcttttgata atcaagacga agtgttattc ttagttgatt
    10381 tatggggcgg aacaccgttc aatcaatcaa acacattatt cgaagagcac aaagataaat
    10441 gggcaatcgt cagcggtttg aatttaccaa tgttgattga agcctacgca tcacgctttt
    10501 caatggaatc tgctcatgaa attgcagcac acatcattga aacagcaaaa gacggtgtaa
    10561 aagtaaaacc ggaagaatta gaaccggcag aagcaccgaa agcagcagtt gaagacgcac
    10621 aacctaaagg agcacttcca gaaggaactg tggtcggaga cggaaaaatc aaatatgtat
    10681 tagcacgtgt tgactcacgt ctgttacatg gacaagttgc gacagcttgg acaaaagcag
    10741 tgcaaccaaa ccgtattatc gttgtttcag atgcagtatc aaaggatgat ctgcgtaaga
    10801 gactaatcga acaagctgct cctccaggtg taaaagcaaa tgttattcct attagcaaaa
    10861 tgatcgaagt agcaaaagac cctcgttttg gaaataccaa agcattgctt ttatttgaaa
    10921 atcctgaaga cgtattgaca gctgttgaag gtggcgtaga catcaaagaa ttaaatgttg
    10981 ggtcaatggc gcattcggtc ggtaaagtcg ttgtaagtaa agtattgtct atgggacaag
    11041 aagacgttga agcgtttgag aagcttgaac aaaaaggtgt gaaattcgat gtacgtaaag
    11101 tacctaatga ttcacgcgat aacatggatg atattttgaa aaaagcaaaa gctgaattag
    11161 caaaagcgta ataaataata ttaaaattta taggaggctt atcatgtcta ttatttcaat
    11221 aattttagtc gtattagttg cctttctagc tggtatggaa ggtattcttg atgaatttca
    11281 atttcatcaa ccactagtgg catgtacatt gatcggttta gttaccggta acctcgaagc
    11341 tggtatcgta cttggcggta cgcttcagat gatcgcttta ggttgggcaa atatcggtgc
    11401 cgctgtagca ccagatgctg cattagcatc agtagcatca gcaattattt tagttttagg
    11461 tggacaaggt gttaaaggtg ttccttctgc gatcgcgatt gccgttcctt tggctgttgc
    11521 agggttgttc ttaacaatga tcgtacgtac aatcgctgtt ccaatcgttc atttgatgga
    11581 tgcggctgct gaagaaggaa acatccgtaa ggttgaaatg tggcacatca ttgctgtatg
    11641 tttacaaggg gttcgtatcg cggtcccagc agcagcgttg ctatttatcc cagcacaaac
    11701 tgtgcaatca ttccttgaat caatgccagc atggttaaca gatggtatgg ctatcggtgg
    11761 gggaatggtc gtagctgtag gttacgcttt ggtaatcaac atgatggcta caaaagaagt
    11821 atggccattc ttcgttattg gtttcgttgt agctgcaatt tctcaattaa cattgattgc
    11881 tctaggtgct ttaggtgttg cattagctct tatttacttg aacctttcta aaatgggtgg
    11941 ttcatcaaat aatggaggcg gaagcaactc tggtgaccct ttaggcgaca ttttgaatga
    12001 ctattaatct tgaaggagga aaataaaatg gcagaagaaa aaatcaaatt atcaaaaaaa
    12061 gatcgtttag ctgttgcgtg gcgctctacc ttcattcaag gttcatggaa ctacgaacgt
    12121 atgcaaaacg gtggctgggc attttctatg attccagcaa tcaaaaaatt atacaaaaca
    12181 aaagaagaac gttctgcagc attaaaacgt cacttggaat tctttaatac acacccatac
    12241 attgcttctc caattttagg ggttacattg gctctggaag aagaacgtgc gaatggcgcg
    12301 cctgttgatg atgtagcgat tcaaggggtt aaagtaggta tgatgggtcc tttagctggt
    12361 gttggtgacc cagtgttctg gtttacagta cgtccaatgc taggtgcact aggtgcttca
    12421 ttagctatgg gaggaaatat ccttggacca atcatcttct tcttaggttg gaacattatt
    12481 cgttgggcat tcatgtggta tacacaagaa tttggctaca aagctggttc taaaattact
    12541 gatgaccttt ctggcggatt gttacaagac gtaacaaaag gtgcttcaat tttagggatg
    12601 ttcgtattag ctgcccttgt acaaagatgg gtatcaatca aattcttacc agttgtatca
    12661 actgtaaaat tagataaagg tgcttacatc gaatgggata aattgccttc aggtggtgaa
    12721 ggaatcaaga gtgcatttga acaagttaat aatggcttag ccctttctcc tgaaaaggta
    12781 acaacattac aagacaactt agaccaattg attcctggtt tagctgcatt aggattaaca
    12841 ttgttatgta tgtggttgct taagaaaaag gtttctccaa tcgttatcat ccttggttta
    12901 ttcgtagtcg gtgttgttgg acacgtcatc ggacttttat aatccataaa aatatagctc
    12961 gggcgttgtc ccgagctttt tttatatagt atactgttca taaacaaata tctggaggga
    13021 gaaaatggtt caatcaatca atacaaaagt agacttggta attgatgcta cttcgtttac
    13081 gggtctgaca gattacgggc aaatcatgat aggtgataat ggttttgagt tttaccatgc
    13141 gcgagataga cgcaaatata tccaaattcc atgggaagaa gtggattatg tactagcatc
    13201 agtcatgcta aagggaaaat ggattcctcg atatgccatt caaacgaaaa aaaatggtac
    13261 atacacattt tcttccaaag aacctaaaaa agtgcttcgt gcgatcagag aatatgtaga
    13321 tgaagataga atggtacaat cattgagttt ctttgatgta gtgaaacgtg gtattcgtag
    13381 tatgtttaaa cgcaagtaaa aaataaagaa aacttctaag aggaggtttt ctttattttt
    13441 ttactttgca gaagaaaata tgaaatagca aaaccaatta tttgtcccct ttaaatccca
    13501 tatgctaaaa ttgattagca aagaaggagg ttatattatg agttggttat ggacattgat
    13561 tgttggagcc gtgatcggag caattgcagg tgcgatcacc agtaaaggaa attcgatggg
    13621 ctgtgtaacg aatatcattg ctggactagt cggttcaagt attggacaag cgattttcgg
    13681 cgaatgggga ccaaaagctg caggtatggc acttattcca tctattttag gcgcagtgat
    13741 tttggtagca gttgtctcat ttttctttgg aaaacgatca taagttttta caaaatagta
    13801 aactaaaagg agttgcagcg agactgtgac tcctttttgg ctttatttat ttaaaataaa
    13861 aagaagtttt ccggaaattt ttatttaact gtcgtgtacg aagaaaagtt tgctataatg
    13921 gaaaaaagcg tgcaaagaaa gagggagttt cattatgatg ctacgtgtag aaaaattgcg
    13981 caaaaaaatg caagaagaaa atttggattc atttttggtt accagtccgt acaatcttcg
    14041 ttacttaacg aactttacag gtacgacagg attagctgtt attactttgg aaaaagcatt
    14101 ttttattact gattttcgtt ataccgagca ggcggcagcg caggctcaag ggtttgaaat
    14161 tattaaaaat gtcggaccta tttttgatga ggtagcaaac ttagtacgca aagaagaact
    14221 gcactcatta gcttttgagg aaacaacagt ctcattttta gaatattcgg ttttagaaga
    14281 aatcatcgat gcggaattag tacctgtttc acagatgatc gaagaactca gagaagtgaa
    14341 agatgaagaa gaaatcgcta ttatcgaaaa agcatgtcat attgcggata tggcatatga
    14401 tcacatcctg aaaatgatcc aaccgggcat gactgagatt gaagtcgcaa atcaactaga
    14461 cttttatatg cgttctcttg gcgcttcagg tgtttctttt gatacgatcg ttgctagcgg
    14521 attgcgttcg gctatgccgc atggtgtagc aagcaaaaaa atcatcgaac aaggtgactt
    14581 gatcacattg gactttggtt gctattacga agggtacgtt tccgatatga cacgtacatt
    14641 cgctattggt gatcctgggg aaaaattaaa agaaatttat caaatagtct tagatgctca
    14701 attagcagtt attgatgctg caaaaccagg aatgactggt gtccaattag atgcagttgc
    14761 tagagattat atttcaaaac atggttacgg ggaagcattt ggacattcta caggacatgg
    14821 gatcggttta gagatccacg aaggaccaaa cgtttcttct cgtgcagaaa agcaatttgt
    14881 accaggaaat gtgatcactg atgaaccagg gatctactta ccaggaatcg gtggagtacg
    14941 tattgaggat gacttgttga tcacagaaga tggaaatcgt gtgttgactc gttcaccaaa
    15001 agaattgatc atcttatagt ttcatcaata gaagaagtaa gcgtaaaaat cagtgttcac
    15061 agactttgtt atagaaaatc actcgattta atgatacact atagaagaac ttttaagctg
    15121 taagagataa taaagttggg tgttttctcc aattcatagc agtttgcagc tgatcggcgg
    15181 cagttttctt accacgtgat cactatgccg catcatagag aattcggatg tatctcgtgc
    15241 ttaggcaaag ggaggaataa ataaatggca gatgaaaaaa atttgatttt aaacgcaaac
    15301 caagatttag gagagatcgt gatcgctcct gaagtcatcg aagtaattat cgggattgca
    15361 gcttctaaag tagaaggcgt atacggaatg cgcggaactt ttgccagcaa tgtcactgaa
    15421 ttattaggac gtgcagctca cggaaaaggt gtttacttag caaacgagga agatggcttg
    15481 aaagtagatc tttactgtta tctagaatat ggtgtttcag ttcctaaagt agcaatggaa
    15541 atgcaggaac gggtcagcca gcaagtcctt ttcatgacgg atatcgattt atctgaagtc
    15601 aatatccatg tagtagctgt tgttcctgaa aaattagaac aaccaacaat cgaagaactt
    15661 tttgaagacg aagaggaaga gaatgaataa agaattatca agacacgaga ttcgggaaat
    15721 ggcattgcag gctttatttc cattagactt caatgcagac ctaacaaaag aagatgcgat
    15781 tttcaacgca atcgaattag accaccgcga catgatcaac gaagatgaat cagagtttgt
    15841 tcctgtttat cttgatacgc tagttggcgg tgtctgtgca aaaaaagatg aattggataa
    15901 agtgattgaa aaacatttaa aaaacaattg gcacatcaat cggatctcaa aaatggattt
    15961 ggtgatcttg cgtatcgcga tttttgaaat gacttatgtg acagatgtac cagcggctgt
    16021 tgctttaaat gaagcaatcg agttggcaaa aacatttagt gatgaccgtt cacgtaaatt
    16081 cgtcaacggt gttttatcca atgtattgaa agaattagaa gctggggcgt aagtcctagc
    16141 ttttttctat gaatcatcat aaacctgtta taaatcggga aaattctatg gtagaatgaa
    16201 aacacaaaaa atatctggga gtggttagat ggcagaattg attaacggaa aagaattagc
    16261 tgaaaaaatg caggcagaga ttgctgaaaa aatccaaaaa ttgaaagata atggtatcca
    16321 tcccggatta gtcgttttat tggtagggga aaatccagcc agccaaatct atgtaagaaa
    16381 taaagaacgt gtagcaaaag aaatcggaat ccattcattg gtagagcgtt atcctgagac
    16441 gatttctgaa gacgaactac ttgcagaaat tgaaaaatac aatcaagatc ctagttttca
    16501 tggtatattg gtccaattac cattgccaaa gcatatagat gaagaaaaga tcctgttagc
    16561 tatccgccct gaaaaagacg tagacggttt tcatccgatg aatttaggca gactccttgc
    16621 gggtaaaccg gacaagattc cttgtactcc atacggcatc atgaaaatgt ttgaagctta
    16681 ttctatcgat ccggcgggta aacgagcagt agttatcgga cgaagcaata tcgtcggtaa
    16741 accgatggct cagctactct tgatggcaga tgcaactgtt actgttgctc attctaaaac
    16801 cgaaaatctg gctgaactgg cacaagaagc agatatttta gtcgtagcaa taggacgtgg
    16861 acattttgtc acaaaagaat tcgtaaaacc aggtgctgta gtgatagatg tagggatgaa
    16921 tcgtgatgct aacggtaagc tgatcggtga tgtgaaattt gatgaagtgg agcctattgc
    16981 aggctggatc actcctgtgc caaagggtgt agggccaatg actatcacga tgctgatgta
    17041 tcaaaccgta aaatctgccg aagcttttgg agcaggtgaa tagatggcac aagaatattt
    17101 aactgtcact acattaacga agtatttgaa aagaaaattt gatgccgatc cttatttaga
    17161 acgcgtatat ttaacaggcg aaatatcgaa tttccgttta cgtgccaatg cccatcaata
    17221 tttcagctta aaagatgacc atgcaaaaat atctgctatt atgttcaaag gagcattcca
    17281 aaaattacga ttccagccaa aagaaggaat gaaagtcctt gtcgttgggc gtatttcatt
    17341 atatgaagcg ggaggttctt atcaaatcta tgtagagcac atggagcctg atggaatagg
    17401 tgctttatat caagaattgg aagaacgaaa agaaaagctg atgaaggaag gcctttttca
    17461 agggcctaaa aaaatgctgc cacgtttccc aaagcgaatc gcggtcctta ccagtccaag
    17521 cggagcggtt atccgcgata tcatcacgac ggtgaaaaga agatatccaa ttgtccaatt
    17581 ggttttgttc ccaacagttg tacaaggaaa ccaagcagcg gacaatgttg tcaggaatat
    17641 ccagagagta gaagagatgg gcaatttcga tacaatgatc atcggtcgtg ggggtggttc
    17701 gattgaggat ttatggccgt ttaatgaaga gcgggttgct cgggcgattt atcaagctaa
    17761 tacgccggtg atttcatctg taggacatga aacagatacc acgatcgctg atttagtagc
    17821 agatgttcgg gctgccactc caacagcagc tgcagaatta gctgttcctg ttttgtcaga
    17881 agagttgatg cgcattcaag aacggcaagc tagattgcag caggcgtttg tacgccagat
    17941 ccagcgcaaa caagaacggt tcgagcgtgc tcgacgttcc tatgtatttc ggcagcctga
    18001 aagattgtat gaaggtcaga ccatcaaatt agaccagttg aaacagcgat tatatcaagc
    18061 tacacagcaa atttatcatg cgaaagaaaa acaaacgatc gcattaagcc accaattgga
    18121 acaagtggct ccgctttatc gagttaaagc agctcgccaa gaaactgctt atctagaaaa
    18181 acgcttagaa gagaaaatcc aacaatatat gaaacaacag cagcagcgtt ttgctcaagc
    18241 tgttcaatct cttgatttgt tgagtccatt gaaaatcatg ggaagaggct acagctatac
    18301 gacgttaaat gatcaagtag taaaaagtgt caccgagatt catcaagggg atttgctgac
    18361 gatccattat caagatggaa tcgttaaagg acaagtacaa gagatagaca aaggagaata
    18421 aaaatatgga aaatccaact tttgaagagt cactgcaaga attagaaaaa attgtcatgc
    18481 agttagaaca aggagacgtt ccattagaat cagctctaga ttcgtttaaa cgaggaatgg
    18541 aattaagcaa acattgccaa gatacattag ctaaagcaga agagaccttg acgaaaatga
    18601 tgacagaatc aaatgaagaa gttgattttg acggaaacga ggaaagctga gatgagatta
    18661 actgactttt cagctattca tctacctgct gtagaaaaag aaatcttgtc ttttttagat
    18721 gagcatacaa cggatagagg actctatgat gcgatgagtt attcagtgaa agcaggcggg
    18781 aaaagaatac gtcccttatt acttttaacg gccgttgctt cctttgatga gcctattgat
    18841 gttcccgtct atcaagtagc agctgcttta gaaatggtgc atacgtattc cttgatccac
    18901 gatgatttgc ctgcgatgga caatgatgat cttcgtagag gaaaacctac caatcataaa
    18961 gtattcggcg aagcattagc tatattggcc ggagatggtt tgcttacagg agcattccag
    19021 ctaatcagta tggcacactt aggtaattct cctaagcttc tgctgcttca gcaattagct
    19081 gtttgtgcgg gatcacaagg tatggttgct gggcaagctg cagatatcga gggcgaatcg
    19141 aaaaagcttt ctttagaaga attagcattt attcatgaaa gaaagacagg gcatttgatt
    19201 cgttatgcct tgctggctgg tggcatatta gcgaagcaac ctgaagaaat cttattgcta
    19261 cttcaacgat tagccgaaca tttaggttta gcttttcaga taagagatga tctactcgat
    19321 gtgattggta caacgaaaac attagggaaa acagctggta aagatgaacg tatggaaaaa
    19381 aatacttacc cgcgtttatt aggcctagaa aagacacgtg aggcgttgga gattgagctg
    19441 ttatccgcca acaagatcat agacaaatta gaagaggacg ttttttcttt tgatggcggg
    19501 ctgatgcgcc agatgatcaa gcaatttgat gtggagaaat gagggaaaga atggaaaaag
    19561 aacgcgtaga tgtattagcg gtcaaacaag gattatttga aacaagagaa caagccaaac
    19621 gttcagtgat ggctggtttg atttacaacg aaaaaaacga gcggtttgat aaaccgggag
    19681 aaaaaattcc agtgagtagt gaattaagag tcaaaggtaa aaaacttcct tatgtttctc
    19741 gagggggatt aaaattagaa aaagcactca aagcatttga tctatctgtt gaaggaaaaa
    19801 cattgttaga tattggtgca tccactggcg gatttactga tgcagctttg caaaatggcg
    19861 caaaaatgag ttatgcttta gacgttggct acaatcagct agcttggaaa ataagacaag
    19921 atcctagagt cgtcgtaatg gaaagagtga attttcgtta tgcaaaaccc gaagacttta
    19981 ccttaggaat tccagaagtt gctgttatcg atgtttcttt tatttcacta aaactgatgc
    20041 tgcctccatt acatgctatt ttaaaagaag agggagaagt gattgcttta atcaaacccc
    20101 aattcgaagc aggcagagaa gctgtaggga aaaacggaat tgttcgtgac cctcagaccc
    20161 atcaaaaagt tttagaagac attttgtcat ttgcggcaca aggtggatat gatgtgctgg
    20221 aattaagtta ttctccgatc acggggggag aaggaaatat cgagttcttg gctcacttga
    20281 ggaaagtacc cgaaagcgga acaatcaatt cagctattaa tatggcagaa gtggtttcaa
    20341 atgcacacga acagtttgac cataaataaa ttgtaactgt gaaaatcaag tgagaagtat
    20401 gcggattctt ctttattata ccaaggaaat aagctatcat tgattaagaa gaatatgcta
    20461 aggagcgaag acgtaatgag aaaaaaagat cggcatcgtt tgattactcg attgttgagt
    20521 gagcaagata tccgaaagca ggaagaattt gttgaaatcc tgaaaagcaa aggaatatct
    20581 gttactcaag ctacgatttc cagagatata aaggaactga aactgatcaa ggtaccggct
    20641 tcagatggcg gctaccgtta tagcatacca gctgaaacaa acgaagatgt aaatactaaa
    20701 ttggaaaaac tattaaaaga cgctttcgtg gcagttgacc aaatggaaaa atttgttatt
    20761 ttgaaaacat tgccgggaaa tgcttcggca gcagcaaatt tgattgataa acgttacaag
    20821 aaagaattat tttcgattat caatgatgac gataatgttt tgatgattac acgaactgaa
    20881 gaccaggcag ttttattgaa gaaagacttc ctgcattacc tttaagttga ggagcgaatg
    20941 tgatgctaca agaaatcagt attactaact ttgcgattat tccggaattg cggctttctt
    21001 ttcacgaagg aatgaccgcg ctgaccggag agactggtgc gggtaaatcc attattatcg
    21061 atgctttagg tctgttagca ggaggaagag gttcaagcga ttatatacgt caaggagcag
    21121 aaaaatgtgt gcttgaaggg ttgtttgaac taccaaaaca agaaggattc tctgaactga
    21181 tggttgaatt agggatcgaa acagatgagg acaatctgat tgttcgacgg gatatgtcct
    21241 taactggaaa aaatgtttgt cgagtgaatg gtcatattat cacattagct aatctgagaa
    21301 gaatcggcag ttatttagta gatatccaag gacaaaacga acatcaggaa ctgctccagc
    21361 ctgaatcaca tcttgcttta ttggatcgtt ttggagatgt agctttccaa cagaagaaaa
    21421 agagttatca gcaagaatat atctcttatc gtgagctgga aaaaagggta cgaaaagtgc
    21481 agcaaaatga aaaatcctat gttcagagaa tagatatgct ccatttccag caagaagaaa
    21541 tagctgctgc tgatttgcaa gtcggagaag aagagaaatt aaaagaagaa agagaaaaac
    21601 ttagcaatta tcaaaaaatt gctgatggat tagctgcagg ttacggagca ctgacgaata
    21661 atgaacaaaa cagtgtagat ggtgttggct tggccgtttc agaactgcaa gggatcgccc
    21721 atctagatgt ggagtatgaa gcaatttatg aaaatatcca aagtgcttac tatttgctgc
    21781 aagatgcaat cggcgatatg agtcgtcaga ttgatttatt ggagttagat gagagtcgtt
    21841 tagaagaagt tacgcaacgt ttagaattaa tccgacagtt gaaacgtaaa tacggcgaat
    21901 ccattgagtc aatattggct tactatgacg aaatcaccga agagctagct tcttctgatt
    21961 tttcagaagg tcaattggac aaaatgaaag aggaactaga gcaaaaagag cttctacttc
    22021 agcaacaagc cgcagatctt catgaagcgc gtaaaaaaat cgcaaaagaa ttggaaaaat
    22081 ccattctgca tgaattgaaa agtctgtata tggaaaacac tgagtttgag gtacgtttct
    22141 taaaagaaga aaatagacaa ttgaatcatg atggatttga ccaaatcgaa ttttacatta
    22201 cgaccaatcc aggagagcca ctgaagcctt tggtgaaagt cgcttctggt ggcgaactgt
    22261 ctcggatgtt gcttgctttg aaaactattt tttcttctga gcaaggtgtg acaagtatta
    22321 tttttgatga agtggataca ggtgtgagcg gaagagttgc acaggccatc gcagataaaa
    22381 tttctcaaat atcgaaatac tctcaagttt tgtgcatcac tcatctgcct caagttgctg
    22441 cagtcgccga ctatcaatat tatattgtga aagcagtgat tgatggacgt acgcaaactt
    22501 ctgtttcaga gttgaaaaca aaagaaagag aagaagaaat tgcacgtatg ctggctggaa
    22561 gtgagattac aaaactcaca ctcgaacatg caaaagaact attgaaactc gcaaaaagga
    22621 cctgagccac ctcgcagtgg ttcaggtcct tttcagcagc tgatagctat attttatttt
    22681 tacatgacac tcattacagc agtcaataca acagatccaa tcgttaaaat cagcattgtc
    22741 caaatgacaa attttgttac tttagcaaaa gtacttgttt gttttttttc acgcattgtt
    22801 ttcaacctcg tcattaatta gttgattcaa gtgtacaatc ttttttccat ttccacaaga
    22861 gggctttttt ataaaaactt cccttttttt aaataatagg tagttacgat acaaataaat
    22921 aatgttaata gaactagcca tataaaggca tcatcccttt cagcaatagg taacttaatg
    22981 ttcattccat agatactgcc gacgattgtc ggtatagtta aaataatcgt taaagaagtt
    23041 aaaattttca taatattatt cagattattc gatacgattg ctgaaaaagt ctgattcatt
    23101 tgttctacta gttttaattg aatgcgagaa gtagtcattg cctgctctgt ttccaccaat
    23161 acatcacgta aatgattttt caaagcatga ttttcttgga aaagtttatt ttgcgctagt
    23221 tctttcaatg catctaaatt agcagaagtc gcttctctga aataaacgag gcttttttgg
    23281 atatccatga tttgataaag ttgtttgttt tcagtggata cttgaagttt ggcttccaaa
    23341 gtatcgcatt gagattgaag cgtagctaaa taactgttgt aagagagtgt gacctgccaa
    23401 atgaattgaa agaagatatt gagattaggc gaaatatcac tttttggaaa ggtctggcta
    23461 aagactttct ttaaaaacag tggttcatga ttcgtaattg tgataagctt ctttttgggc
    23521 gtcaaaataa tagagagcgg gtatgtatcc acttgaaaat aaccgctagg acttgtttta
    23581 gcaaaaggat attgtaacaa taataacgct ggctttgtca actttgattg attgaattct
    23641 tctgtacggg aattttctgc atcgtccaat atggaagtga tgtaatctga cggaatttca
    23701 aattgatgtg tcagctgatg aatctcttct tgattaggac gttctacaca ataccagatc
    23761 gtttggtcag tttcctttcc ggtattacgc agtttctcat tatctaatgt aaaatatttg
    23821 atcatgattt tcctcctgtt gcctgtttct tttattataa cggataggga attggaatac
    23881 atggaatgtg tttgtaagat atagaatata actgcataaa tttaaataaa atgaaacagt
    23941 tgtgtaaagt atatacagta tacttgaagc aacgataaaa aaggagttta cgttcatggg
    24001 cacattcaca ccacttatct tgttttggta tatttacccg gtaatcgttt tgtttggttg
    24061 ccaatttctt gtaaaattat tttcgttaaa tcgtcgtttt aaaataaaag cccctgattt
    24121 ggcgattcct tttttgtggg gcggtatgca tgcattgtct agaaatacag ggacaatttc
    24181 tatcttaccg tttttcttta tttctgtttt gctaatggga atttgtattg ctgttttcca
    24241 agcatattat tatgaagaaa ttatttatcc gcgttatttc aagatgactt ggcgtttggt
    24301 ttttctgttg acaatcgtct tgtacgctgt cttgatcatt gtgaacatac tttcttacct
    24361 atgaaaaaaa tagaaaagct gtaaaaagtc ttttaaaagg ctttttgcag cttgattttt
    24421 aaaaaaatgt ttatgaataa aaaaagttgt tcccggattt cccagaaaag gtggtagaaa
    24481 gtgggggatt gtggtagact aattttagtt agtggaggaa tggggggctt tcaatgttga
    24541 tgggtgaatt ccaacataat attgatgcaa aaggacgttt aatcgtgccc tcaaaacttc
    24601 gtgaagaact tggcgaaaag tttgttctga cacgcggatt ggatggctgt cttttcggct
    24661 atccgatgag cgaatgggaa aatctggaag ctaagctgaa cgaaatgccg ttggctaaaa
    24721 aagacgcacg tacttttgtg cgattcttct attcggctgc cactgaatgc gaacttgata
    24781 aacaaggacg aatcaatata cccagcacgt taagaaatta tgcagctttg acaaaaggtt
    24841 gcgtagtcat cggtgtatct aaccgaattg aaatttggga tgagacacga tggcaagatt
    24901 tttctgcagc agcagaagag aactttgacg aaattgctga aagtatgatt gatttcggac
    24961 tataagaata ggaagaggct gactaatgac tgaaacattt caacactata cagtcatgtt
    25021 gaaagaaacg gtagatggat tgaacatcaa accggatggc gtttatgtag actgtacact
    25081 cggcggtgcc ggacatagtg aatatttatt aagacaacta agttctaaag ggcatctgta
    25141 tgcgtttgac caagatcaaa aagcaatcga tcacgccaag ctgcgtttag cttcttatgt
    25201 cgaacaaggt atggtcacat ttatcaaagc gaacttcaga gaattagaag aacgcttgag
    25261 tgagcatgta gataaggtag acggcatttt gtatgatcta ggggtttcct ctcctcagct
    25321 agatgaagca gaacgtggat ttagttatca tcaagatgca ccgttggata tgcgcatgga
    25381 tcagtcagct cctttatccg cttatcacgt aattaatgaa tattcctacc atgaattagt
    25441 aaagattttc ttccgctatg gcgaggagaa attttccaaa caaattgctc gtgaaatcga
    25501 acgagtacga aaaacaaaac caatccaaac aactggtgag cttgtcgaaa tcattaaaca
    25561 agtcatccca gctcccgcaa gaagaaaagg cgggcatcct gcaaaaagaa tttttcaagc
    25621 tgtgcggatt gcagtaaatg acgaactcgg tgccgaagag gcctctttag aacaggcaat
    25681 ccggttattg aaagtcaatg gaagaatcag cgtaatcaca ttccattcat tggaagacag
    25741 aattgtcaaa agtatgttta aagaatatag tacggtacaa gatctaccac cgggacttcc
    25801 tgtcatacct gacgaattcc aaccagaact gaaagtcatt actcgtaaac caatccttcc
    25861 ttcagaggaa gagctaacag aaaacaatcg atcacgcagt gcaaagttac gtattgcaga
    25921 aaaaataaga atgaaagagg agtagaatga tggcagaatt aaagaaaatg caagattacg
    25981 aatatgattt acctgaattg gtggatcagc cggaacaaca aatgcctgat tcttcttcga
    26041 atcaagaaat cattcttcca caatcaccgg caaaacgatt aaagcagatt tctgctttgg
    26101 aaaaaattgc tgtggcaagc gtggcgattg ctattgttgc tttatgtgtt ttaacagtta
    26161 tgctgcgcac aaatatcagc ggagctgaaa aagaaatcac gtcaatacaa acagaaatca
    26221 atgataaaaa gcaagaaaaa acgagtttag aacaagaaaa aaacgaactt tctcgtactg
    26281 aacggattaa acaaatcgca gaagaaaaag gattgtctat taatgacgac aatttaagga
    26341 aagtgaagta aatgagtctt aaaaataaaa tttggcggtt tatggaaaag aaaaatctaa
    26401 atccgatgaa caatcgcaaa aaagtaggta tcattttatt tgctacgagt attggattgt
    26461 tctttttatt tgccgtccgt ttctcgtata tcgttattgg aggtcatgtt gctggtacct
    26521 cattagctga aaaaacaaaa cagttgtacc aaggaagtga agtagtaaaa gcaaaaagag
    26581 gaacgattta tgatcgtaac ggtgtggcgc tcgcagaaga tgcctcctct tattcaatta
    26641 aagcgatact ctcaaaaaca tatacctctg gggataaaaa actgtatgtt gaagaaaaga
    26701 attttgataa aatagcagaa atcctgcata agaatctttc tatagacaaa aaagatgcac
    26761 tgaatatttt agaggacggc gcaaaaaaag agctgtatca agttgaattt ggtagctatg
    26821 ggaaaaatat ctcccaagaa accaagcaaa acatcgaagc ggacatgaaa aaagaaggtg
    26881 tcgctggtct ttattttgtc gaccatcagg ctcggatgta tccaaatggc gtcttttctt
    26941 ctcattttat tggatacgca gttccagaca aagatgagaa tggcttagtt ggtaaactag
    27001 gtttggagtc tgcttacaat gatatcttga gcggtaaaga tggtaagatt atttatcaaa
    27061 aagataattt tcaaaatcct ctgccaggta cagtggcaga agaagaaaaa gctgtcgacg
    27121 gacaagatat ctacacgact ttagacagca gactacaaag ttatttagaa acactgatgg
    27181 atcaagtaaa tgaagaatat cagccagaag aattgacagc agtcctgatg aaagcaaaaa
    27241 ccggagaaat cttggcaatg ggacaacgac ctactttcaa tcctgaaaca atggaaggat
    27301 tgactggaaa agatgctatc tggcgtaatt tcttggtaca agatagttat gaaccaggat
    27361 caaccatgaa agttttcact actgcagctg ctatcgaaga aggagaattc aacgagaatg
    27421 aaaccttcca atctggaaaa atccaagtag aagatgctac gatcaatgac catgactttg
    27481 gtgaaaaagg tgtgctgacc atgcgtcaag ctctttcatg gtcaagtaac gtcgggatgg
    27541 tcatactgga acagcgatta ggcggacgat ggtataacta tttacaaaaa ctgggatttg
    27601 gacaaagtac tcattctgga ttagatgatg aagtaaacgg tgctttacct acattaaata
    27661 ttgtcgaccg agcaatgagt gcttatggac aagcggtagg tgtgacgaat ttccaaatga
    27721 tgaaagcttt cacttctatt gcgaataacg gtacaatgat tcaacctcga tatatcagca
    27781 aagtggtgga tccccaaact ggagaagagc gaacaactca aacagaagtt ctagggcaac
    27841 ctttttcaaa agaaacaaca gaaaaagtcc gtgaatatat gagagatgtt gtcgaaagcg
    27901 aaaactacgg tagtgcttat ggtgtatata gtgtacctgg atacaatgta tcggcaaaaa
    27961 ccggaacagc ccaaatcgct tctgatacag ggggatatca aacaggagat acagcctacc
    28021 tgtattcgat tgtggagatg gttccttctg aagatccaga ctatgtcttg tatctaacaa
    28081 tgaaacaccc taagacatat gatcgaatgg cattggctaa aatcgcaaat ccattgatga
    28141 aacgggcaat ggattttaaa gaaactgaag aagattcaga tacagaaaca aaaacagaaa
    28201 aagtatccgt agccgattat cgtaatcttg aagcggacgt tgcagcagct gatgctcaaa
    28261 aaagtggact gcaacctgta gtgatcggta atggtaaaaa agtacaaaaa caatctactg
    28321 ccaacggtga tcagttgatc tctggagaaa aactgatcct atatactggt ggtgataagc
    28381 tgatgcctga cgtaacagga tggtcaaaag cagatatcat gaagctgggg aaaatcctcg
    28441 gtattgaagt tagttttgat ggagatggtt attgtgtcaa acaagaactt gctccatatg
    28501 aaaaaatcac tgaagacaaa cttagtttta ctttagaaga ataagaagag aaataggaga
    28561 gaaaagagca tggaatggac acaagcattg attcccattg tcagcagttg tgcaatgaca
    28621 attgccgcaa tgccgctatt tattggttat tttcaaatga aaaagcaagg tcaggcgatt
    28681 cgtgaggagg gaccaaagtg gcacaatagc aaagccggaa ctcctacaat gggcggctta
    28741 gtgtttctga tcggctctat tttgacagga atttgggttg gagcttggca aaaacagcta
    28801 actcctactc ttttcatctt gctttttgta ttagcgttat acggagtaat cggctttctt
    28861 gatgatttta taaaaatatt caagaaaaga aacatgggac tgaactcgaa gcagaaattg
    28921 attggacaga ttctaggggg aatcatcttt tatcttgttt accgttctga aggttatcca
    28981 ggtgtattga atttcttcgg actagatcta cctttaggaa tcatttatgg tattttcgct
    29041 ctcttctggc ttgttggatt ttcaaatgca gtaaatctga cagatggcat cgatggatta
    29101 gttgctggct taggaagtat ctcttttgca gcttacggtc taattgcttg gcatcagcat
    29161 cagtatgatg tattaatcat ttgcttaagt gttttaggag gtttactggg tttcttcgtc
    29221 tacaacagaa aacctgccaa gatttttatg ggagatgtcg gttcattagc gttgggcgga
    29281 cttttagcgg caatttctat aatgctaaac caagaatgga cattgctttt gattggtttg
    29341 atctatgtta tggaaacagc aagtgtgatg cttcaagtta cttcctttaa gcttacagga
    29401 aaacgaattt ttaaaatgtc tccaattcat catcactttg aaatgtgcgg atggtcggag
    29461 tggaagattg atacagtttt ttggttgatc agcattgtga cttcgttgat cacattatgg
    29521 atcgtttggt aggagatgac gggaaatgaa aaaaatatca acatatgaaa ataagaaagt
    29581 gcttgtctta ggactcgcaa aaagcggagt aagtgcggcc aaattattac atgaattggg
    29641 cgcacttgtc accgttaatg atggaaaacc ttttgacgaa aatccggaag cacaagagct
    29701 gctttcttta gggataaaag taataacagg tagtcatcca atcgaattgt tggatgaaga
    29761 attttcattg atggtcaaaa atccagggat tccctacagt catcctttag tagcaaaagc
    29821 ccaagaaatg ggtattccgg taattacgga agttgagcta gcttacgaag tagcggaatg
    29881 cccaattatt gggattacag gaacgaacgg aaaaacaacg acaacaacga tgacaggact
    29941 actactgaat gcaggagcag atcaaggaat tgcacgttta gcgggtaata ttgggtatcc
    30001 agcaagtggt gtagcgcaag aagcaaaatc agaagataaa attgtgatgg aattgtctag
    30061 cttccaactc atgggaatca cagatttccg ccctcatata gcggtgatta ccaatatcta
    30121 tgaagcacat attgattatc atggtacaag aaaagaatat gtcaaagcta aatggaacct
    30181 tcaaaaaaac atgacagaaa aagattatct gatccttaac tggaatcagt cagaactaca
    30241 agaattagcg caaagaacaa aagcacgcgt actgcctttc tcgacaaaag aagtgttgga
    30301 agacggtgtg tatgctgacg attactcaat atactataaa aaagaaaaaa taatggaaat
    30361 atctgaactt ggcgtaccag gtaagcataa tgtagaaaat gcactagctg ctatttctgt
    30421 agcaaaattg tatggtatat caaatgaagc tatacgagaa acgttgcatt ttttccatgg
    30481 cgtaccacat cgtacgcaat atgtaggaga aatccaaggc agaaaatttt ataatgattc
    30541 aaaagcaacc aatattttag cgactaaaat ggctctaagt ggatttgaaa cgtctaaggt
    30601 cgttttattg gctggcggat tagacagagg aaatacattt gatgaattaa ttccttcatt
    30661 aaaaggaatc aaagcaatgg tcgtatttgg ccaaacaaaa gaaaagttga tggatgctgg
    30721 aaaaaaagca ggcatcgaga caatagtaac agccgattct gtagaacaag cagttccttt
    30781 agcattagaa aacagtacag atggtgatgt agttttatta tcaccagcga atgccagctg
    30841 ggatcaatac ccaaattttg aaactagagg aaacagattc atggaagctg tgaaccgatt
    30901 aaaatagaaa aagtagaagc gagcgataaa aaatgaaaat tttggttaca ggcggaggaa
    30961 cagggggaca tatttatcca gctcttgcct ttgtcaatta tgtaaagact caagaaccga
    31021 atgctgaatt catgtatgtg ggagcaaaac gaggtctaga aaacaaaatc gtccctgata
    31081 caggaatgcc tttccatacc ttggagattc aaggatttaa acgaaaaatt tccatgcata
    31141 acatcaagac ggtccgattg tttcttaaga gtatccgtca agcaaaaaaa atcctcagtg
    31201 attttcaacc agatatcgtt atcggtactg gaggatatgt ttccggagcg gtagtgtacg
    31261 ctgcagccaa aatgggtatt ccaacagtta tccatgaaca aaacagtgta ccaggtgtta
    31321 ccaataaatt tttaagccga tatgtggatc ggatcgctct ttcatttaaa gatgcggctt
    31381 ccttttttcc tgaaaacaaa gcagttcttg taggtaatcc tcgagcacaa gaagtagcag
    31441 atactaaaaa atcagatatt ttgaaaacat ttgatttgga tccagaaaag aaaacagtct
    31501 tgatttttgg cggtagtcaa ggagcactta aaatcaatca agcagtatca gtttttttaa
    31561 gtgaatatat tccttcttct taccaagttt tgtatgcttc aggagataga tattatgaag
    31621 agatcctaaa taaaataaat cctgaaatac aaaatattag tgtccagcct tatatcaaaa
    31681 atatggcaga ggtcatggct tccagtgatc tgctggtggg gcgtgctggt gcaacttcga
    31741 tcgcagaatt cacagctctg gggttaccgg cagtgttggt tcccagccca tatgttacga
    31801 atgatcatca gactaaaaat gcaatgagtc ttgttcacgc aggagcagca aaaatgattg
    31861 cagataatga actaacaggt gaatcactaa gtcagacagt caacgaaatc atgggtgatg
    31921 aagaattgca aaagcaaatg tgccgagctt ctaaagaaca aggaatccct gatgcttcaa
    31981 aacgtcttta tgacttagta aaacaaataa tcaaaaaata aaggcggtgg tcttagtgag
    32041 taagaaaaaa gaaccaaaaa aattgtctca tccgtcttct gatgaaaaca atttgactcc
    32101 ttggcaaaag gctaaccgaa aatatctggc agaacaagag atgaaaaacc aagagccaaa
    32161 aaaagaagac ataacattag atacacccct ttcagattct gaagaagaaa aaacggttca
    32221 agaggaacag caagaagaaa gccagtccga gaaaaaaatc gaattttttg aagagatcaa
    32281 gcaaaagaaa aacggtggac catataacgg ttcttttttg aaccggctgc ccaatttaaa
    32341 aagtcaacgg cacaaagtac tatttcgtcg gttagctttg atcatcactg tattgggtat
    32401 accgctgatt tttttgatct attatgtttc tccttatagc aaattacaag cagttgcagt
    32461 atcaggcaat aagacagtca acagccaaga aatcatctct gatacaaaat tgtcattagg
    32521 agaaaatgtt tggggacagt attttcatcg atctacttat atcgatcgcc ttaaaaaagc
    32581 acagccaaga atcgaaacag caaatataca tttcaaaggg atgaatgaat tcgatttgga
    32641 tgtaacagaa tataaagaga ttgctttgat cgcaaaaaac aatcaatact acccagtgat
    32701 tgaaaatgga acagtattag atgaaaaagt agcaaatcct acaaaaaatc tccctatctt
    32761 ggaagagttc aaagactctg caaaaatcaa agaattaaca aagcaataca atcagttatc
    32821 atcagaatta caaaaagcaa tttctgaaat caagtacacg ccaagagcaa gcaataaaaa
    32881 tctgatccaa ttgaatatga atgacggcaa tcaagttatt gtaaatatca ataatcttgc
    32941 gaaccaaatg aaatattatt cgcaagtagc caaagatatg gatgaaaaag gtgtgatcga
    33001 catggaagtt ggtatcttct cgcatcctta cggtagcact caagaaacgg aagaatcggg
    33061 ccaatcggaa gaaacaactg aaagtgaaga aaatgcggat caaacaaacg aatcaagtga
    33121 agaggcagaa acgcaaaaag cacaaacacc tggatcgtct agcacaaacg gatcatctga
    33181 ttcaaatgat tcaagtgaaa caagtcaaat agaagataat ccaagtacaa ctccgtcaag
    33241 tttaaatgaa aattgataaa acaactttaa aaagtaagaa tgtactttct aaaaaccagt
    33301 aatttatggt agaattggaa gcagtgaata tatctattaa taagtatatt ttaaaacgga
    33361 cgctagttgt tcgcttgtat atggaatagt aagtaggagg gaatcccatt catggcaaaa
    33421 acaggaatgt atgtaggcct tgatattgga acgacatctg ttaaagttgt cgtggctgaa
    33481 tatatcgaca gccaaatgaa tattattgga gtaggaaacg caaaatcaga agggattaac
    33541 cgaggcatta tcgttgatat cgataaaacg gtccaagcga tacaacgagc agtacgacaa
    33601 gcagaagaaa aagcaggtat ccagatcaaa ggcgtaagtg tcggtttgcc agcaaacatg
    33661 cttgaagtag aaaattgcca gggaatgatt gcagttaacg gagattcaaa ggaaatcacc
    33721 gatgaagatg tcagaaatgt ggcttcagct gcccttgttc gttcaatacc tcctgaacgt
    33781 caaatcgtgt caatattgcc acaagatttt actgtcgatg ggttcgaggg aatcaaagat
    33841 cctcgtggaa tgatcggcgt aagattagaa atgtacggtc tgttgtttac aggacctaaa
    33901 acgatcatcc ataacatacg taaatgcgtg gaaaatgccg gattaatcgt caacgaaatg
    33961 gtgattactc ctttagcgct gactgaatca attctttctg acggagaaaa agattttggt
    34021 acgatcgtca ttgatatggg tggcggccaa acaacaacgg ctgttatgca tgataagcaa
    34081 ttgaagttta ccaatcttga ccaagaaggt ggcgaatttg tcactaaaga tatctctatt
    34141 gtattaaata cgtcatttaa caatgcagaa gcgttgaaaa taaactacgg ggatgcatac
    34201 ccagaacgga catcaccaga tgaagaattt ccagtagatg tgattggtca gtcagaacca
    34261 gtgaaagtcg atgaacgcta cttgtcagaa attatttcag ctcgaatgga acagattttc
    34321 aacaaagcaa aagatgcatt ggaccaaatc gaagcattag agttgccagg tggcgtcgta
    34381 ttgacaggcg gagctgctag tcttcctggt gttgtggact tggcacaaga aatcttcggc
    34441 gtaaatgtaa aattgtatgt tccaaatcac atggggctga gaaacccggt atttacaaat
    34501 gtaataagta tcgtggatta ttcagcaaac ttgagtgaag tgtatcaatt ggcaaaaatt
    34561 gctgttacgg gtgaaacctc agcagctcgt caaatggtag ttgaacaaga aacaacaaac
    34621 acatatgaga gctatgaagc acctgaagaa acaatctacg atgagccgga accaaaagag
    34681 tccggagaaa atgtaaaaaa taaaatcaag ggtttcttta caaatatttt tgattaattc
    34741 atcctgggag gaataagata tggaattctc aattgataat aatatcaatg acggcgcagt
    34801 aatcaaagtc atcggagtcg gtggtggcgg tggaaatgct gtaaaccgaa tgattgaaga
    34861 aaacgttaaa ggtgttgaat tcattacagc caacacagac gtgcaagcat taaaaaattc
    34921 aaaagctgaa acagttatcc aattaggccc caaatatact cgtggtttag gtgctggttc
    34981 tcagccagaa gttggacaaa aagcggcaga agaaagtgaa caatccttac gcgaagcttt
    35041 agacggtgca gatatgattt tcatcactgc aggaatgggt ggaggaaccg gtacaggtgc
    35101 tgcaccaatc gttgcaggta tcgcgaaaga attgggcgca ttgactgttg gtgtcgtgac
    35161 acgtccattc acttttgaag gaccgaaacg tggccgtttt gctgcagaag gtatcgctcg
    35221 tttgaaagaa aatgtggata cattattaat tatctcaaat aaccgtttat tagaagttgt
    35281 agataaaaag acaccgatgc ttgaagcttt ccgtgaagca gataatgttt tacgacaagg
    35341 tgtacaaggt atctctgatt tgatcacagc gccaggttac gttaaccttg actttgctga
    35401 cgtgaaaaca gtgatggaaa accaaggtac agcattgatg gggatcggtg tggctagtgg
    35461 agaagatcgc gtagtagaag caacgaaaaa agcaatctcc tctccattgc ttgaaacatc
    35521 tattgatgga gctgaacaag tacttcttaa catcacaggc ggtttggata tgacattgtt
    35581 cgaagcacaa gatgcttcag atatcgtagc aaatgcagca actggcgatg taaatatcat
    35641 tctaggtaca tctatcaatg aagaaatggg cgatgaaatc cgtgtgacgg tcatcgcaac
    35701 aggtatcgat gaatcaaaaa aggaacgcaa gtctagccga ccagctagac aagcacaaat
    35761 gcaatcacct gctcaaaaga ctgtattaga tatggatcaa gctaaaccaa cttcttcaga
    35821 agaagaaaac agttttggcg attgggatat cagacgtgaa caaaatgttc gtcctagagt
    35881 tgatgattcc aattttgaca atatcgaaaa aaaagaattt gatacattca accgcgaaga
    35941 aacaaaatct catggcgatg atgaattaaa tacgccaccg tttttccgtc gtaaaaaata
    36001 aaggagagga agagcacatg attgctgaca acttgcagaa aatcaagcaa gaaattcagg
    36061 attcgtgtgc tcttgttcat cgtgatccga aagaagttac attagtagct gtaacaaaat
    36121 ctgttgaatc cgctcaagct gaagaattgg ttagagctgg cgttatgaat tgtgcagaaa
    36181 accgagtaga taaattatta gaaaagaaac aagatttatt tgattttcct gaaataaagt
    36241 ggcatttaat tggtaattta cagcgcagaa aggtaaaatt gattgtaaat gaaattgatt
    36301 actttcatgc gttggacagt ttaagattag cagaagaaat ccagaagcgg ttagagaaag
    36361 aattatcctg ttttattgaa gtaaatgttt ctggtgagga atcaaaacat ggaatttcac
    36421 cagatgagct tttaccgttt gtggaatctt tagctgcctg cacaaaaatc aaggttgttg
    36481 ggttgatgac tatggcgcct aaagaagctt ctgatgagca aatccataaa gtgtttggta
    36541 cgctgaaaga attgcgtgat cttgttcaag caaaaggtta tgcccatgca ccatgtagtg
    36601 aattaagtat ggggatgagt caagactttc aaattgcgat tgaagaaggt gcaacattta
    36661 tccgtgtagg aacagcgcta ttcaaagacg aataaaggag gaacaaaaat gccgctttta
    36721 aacagaggag caattgctaa ttttttcgga ttagctgatg aggaagagta cgaataccaa
    36781 gattatcctg aaacaacaaa aaaggctgta cagccaacta aaaaaaatac aacacagaat
    36841 caatcaactc attctgtatc tgctgcgaat actcatgaaa aacaaaaaac ggcgacttca
    36901 cgtcctgtaa cgcatgaaag tattcagccg gctgaaaaga aaaaagtaat tgaactacat
    36961 caatcaccta caaaaactgt agcgaaagaa agaacagctt caagaacctc tacacaacct
    37021 aaagcaaatc ttgctggaaa aatcactgta atggaaccaa gagcttattc tgaagctatg
    37081 gcgattgcta aacgaatcat tgctggagaa gcaaccttag tgaattttca tttagtagaa
    37141 gaaaaacaag cgagaagaat cgttgatttt ctaacaggaa cagtttatgc actagatgga
    37201 gatatcaaac gtgttggaga tgagattttt ctttgtacac cgactgggat ggagattgac
    37261 agttcaaccg ctcaatcttt tgcagatgcg aatttgtttg atctgtaaga ggaggaacta
    37321 cgatttatac tattgcacta ttacttcatt tacttcaacg ggcagcctat ttctatagca
    37381 ttatcttgat ggtatatgca ttgctctctt ggtttccagg cgggtatcaa tcagggctag
    37441 gacgattatt agctaagatc tgcgaaccgt atatcagttt gttcgatcgt ctgcctttga
    37501 ggattggacc cttggatttc acaattttag gggcaatcct gatcttgaac ttagccgtac
    37561 aaggtttagc acagatcgtt atatggataa ctgtccattt agtttattga ttgaagcaac
    37621 aaaatcttta ttctcagaat agataggagg ggaaaatttt ggatgcaaat gtataccagc
    37681 actttcgggc agatgaacgt acatttatcg attcggtagg cgattggatt gaacaggttc
    37741 aaggacaata tgcaccctat ctgaccgaat ttcttgaccc aagacaatcc tatattttag
    37801 aaacactgat tcgacaaagc agtgatttgc gtttcatgtt ttatggcgga tatgaacagg
    37861 cagaaagaaa aagatgtttg attttccccg attattacga acctgtagag gaagattttg
    37921 aaacagcatt gtatgaaatc cattatccta gcaaatttgc cagcctaagt catgggaaaa
    37981 tccttggaac tttagtggga acggggatca aacgctctta ctttggcgat atcatctcgg
    38041 acggtgatcg ctggcaagta tttattgcaa atgaggtgga tcattttgtt gctgcacaag
    38101 taacaaagat tggaaaggtt gctgtacgct tggaaccaat caaatacaca gaaatgatta
    38161 tgccgaaaga tagctggaca caagaaagag gaacagttag ttccatgcga ctagacagtg
    38221 tgatctctga gatttataat atttccagac agcggtccaa gcagctgatc gaagctggta
    38281 aagtaaaagt gaactggaca gaaaatacaa gacctgattt tgtacttgaa ctattagata
    38341 ttatttcagt cagaggttat ggcagagtcc agatccaaga acttgagggg aagacgaaaa
    38401 aagaaaagta cagggtactg ttcggtgtat tacgtaaata aaataaaaag gtggtttact
    38461 catggcttta actccattag atatccaaaa taagacattc ccgacaaaaa tgcggggata
    38521 taatcaagac gaagtagatg atttcttaga tttagttgtt cgtgactatg aggaattgac
    38581 tcaaagaaat cgagaattag aaaaagcagt caaacattct gaagaaaaac ttgagtactt
    38641 caatgaatta aaagatgctt tgaaccaatc aatcatcgta gctcaagata cggctgataa
    38701 agtaaaaaca agtgcaagca aggaatccga agtgatcgtt acttctgcac aaaacaaagc
    38761 agatgagtta gttgcgaacg ctgaaaaacg tgcacatcaa ttaacaactg atgcagaaga
    38821 aaaagcaaga aaaatcttga cagatgcaac agaaaaagca agacagcttg cgacagaaac
    38881 tgaagatctt aagaaaaaaa cacgagtatt ccatcaacgt atcagcttga tgcttgagtc
    38941 tcaattagaa caagtgaaaa gtccggaatg ggatgaaatt ttacaaccat tctccagcta
    39001 cgtgactgac agccatgaag tgatcaaaga agttttagca aaacagcttg acaatgaaaa
    39061 tgatactgat gtaaactcag acacaggagt catagaagca cctatgacgg catttgatac
    39121 acaggctatt gatatctcga tcgtgcctgg tgaaaatgaa aacgagtaga acagaaaagc
    39181 actttgttat tcttaaagcg agccgatgag agtggaagtt cggtaagaca ctgcatggtg
    39241 aaagatcctc tacttgagac ctgcttttcc gaaattagag taagaagcag cggctgacct
    39301 cgttattggt cacagagagt ttgcactaga tagatgcaac taaatttggg tggtaccacg
    39361 gcatgttcgt cccttgcggc tgaacatgct tttttgtgtc cggaaaacaa ataaaggagt
    39421 gtatggttga atgaaaatga aagaaacctt gcaattagga aaaacaaaat tccctatgcg
    39481 tggtaatttg ccaaaccgag aaggcgagtg gcaaaaagaa tgggaagaaa atcgaatcta
    39541 ccaaaaaaga caagagttga acgaaggaaa acctagcttt gttcttcatg atggacctcc
    39601 atatgccaat ggtaatatcc atttaggaca ttcattgaat aaaatcagta aagacattat
    39661 cattcgttca aaatcaatgt ctggctatcg tgcaccatat gttccaggat gggatacaca
    39721 tggattgccg attgaacaag tattggctaa taaaggcgtg aaacgtaaag aaatgtccat
    39781 ggcagaatac ttggaaaaat gtcgtgaata tgcactttcc caagtagata agcaacgagc
    39841 agatttcaaa cgcctaggag ttgcaggaga ttgggaacat ccttatgtta cattagatcc
    39901 ttcttatgaa gctgcacaag tacgcgtatt tggtaaaatg gctgaaaaaa gctatattta
    39961 caaaggattg aaaccaattt actggtctcc gtcaagtgag tcttctttag cggaagctga
    40021 aattgaatat aaagatgtaa aatctccatc tatttttgta gctttcaatg tcaaagacgg
    40081 caaagatatt cttgatgaag atacagcttt tgtcatttgg acgacaacac catggacatt
    40141 gccagcaaac caaggtattg ctgtaaatcc aaaatttacg tatgtattgg tggaagccga
    40201 tggccgtaag tttgtcgtag cgaaagattt gctagaaaca gtccaatcag aaatcggttg
    40261 ggaaaatgta acagttctaa aagaatttgc tggacaagaa atggaatata tgactgcaag
    40321 tcatccattc tatgaacgtg aatcacttgt gattttaggc gatcatgtta ctttagacgc
    40381 tggtactgga ttagtccata ctgctccagg acatggggaa gatgactata tcgctggtag
    40441 caaatataaa ctatctgtag tgtcacctgt agactcaaaa ggattgttta cagaagaagc
    40501 acctggattt gaaggtatct tttatgacaa agcaaatcct atgatcactg atctattaaa
    40561 agaaaaagga gctttgctga agctagattt ctttactcat agttatcctc acgattggcg
    40621 gacgaaaaag cctgtgatct atcgggcaac tccacaatgg tttgcatcta tcgataaatt
    40681 ccgtcagaat attttggatg aagtagaaaa agtagagtgg gttatcccat ggggtaaaac
    40741 acgtttgtat aatatgatcc gtgaccgcgg cgattgggta atttcccgtc agcgtgcatg
    40801 gggagtacca cttccgattt tctatgctga aaatggagaa gcaatcatca caccagaaac
    40861 aatcgaacat gtggcaaaat tatttgctga acatggatca attatctggt ttgaaaaaga
    40921 agcgaaagaa cttcttcctg aaggatttac ccacccaggt tctcctaatg gcgaatttac
    40981 aaaagaaaaa gatatcatgg atgtctggtt tgattctggt tcttctcatg aagctgtttt
    41041 acgtcagcga ccagaattat cattcccagc agatatgtat ttagaaggat cagaccaata
    41101 tcgtggctgg ttcaactcaa gtatcacgac tagtgtggct atcaatggtg tagcaccata
    41161 caaatcagtt atttctcaag gatttgcttt agatggtgaa ggccgtaaga tgagtaaatc
    41221 tttaggaaac atcattgcac cagaaaaagt gatcaaacaa tttggtgcag atatccttcg
    41281 cttatgggta tctagtgtag attatgaagc agatgttcgt gtttctatgg atatcttaag
    41341 tcaagtggca gaagtatatc gtaaaatcag aaatacgatg cgtttcttat tagcgaatac
    41401 agaagatttc gatcctaaaa aagatactgt ttcgtacaat gatttacgtt ctgtagacaa
    41461 atatatgacc gttcgattga accaagtaat caaagaaatc cgagaagaag ggtacgacaa
    41521 atataacttc atgcatattt accgtacagt tatgaacttc ttgacggttg atctatcgtc
    41581 attctacctg gattttgcta aagatgtagt ttatattgaa gcagaagatg attatcaacg
    41641 tcgttgcatg caaactgttt tctatcaaac agctgtagct ttgacaaaat tattgactcc
    41701 tatcattccg catacagcag aagaaatctg gtcattcctg aaagaagaag aggagtacgt
    41761 tcagttaagc gagtttcctg gttatgaaga gtttgcaaac caagaagaat tgatggatac
    41821 ctggactgct ttcatggact tccgtgataa tgtcttaaaa gcattggaag aagcaagaaa
    41881 cagcaaattg attggtaaat ctttggaagc aaaactaact gtttatccaa aacaacaagt
    41941 tcgtgaaatg ttaaaagctt tggatgcaga tattgcacaa ttattgatcg tttcaccaga
    42001 ctactttgaa gttatggcag cagatgaaca agtgccagat aacgctatgg tatttgatga
    42061 tgttgctatt acagtggaaa aagcagacgg ggaaacttgc gatcgctgtc gccaagttcg
    42121 taaagatgta ggagtagatg aaaaacttcc tcatctatgc ggtcgttgtg caaaaatcgt
    42181 tgaagacttc tatcctgaag ctgtagctga aggattcgaa gaaaagtaaa agggaaaagg
    42241 gggtgtgaca tgttctttgt cacaccccct tttgttatca atcgtttaat tttccacgtt
    42301 cacgatacca gttatctggt tgccagatcc attcgaatcc gtctttttca agtagttcga
    42361 aagctgcttt aggtcccatt gatccagctt tgtagttggg aaaatccggt tgtgtttggt
    42421 cccaagcttt tcgaatgaca tccacgatat gccaagattg agcgacttct tcccaatgag
    42481 agaagttcgt tccatcacca ttcaacgcat ctaatagtaa tttttcgtaa gcttctgggc
    42541 tattttcaac catttctgca ctatttctaa attccaattt gattggttcc gtttcaaatc
    42601 cttgccctac ttctttccca ttcaaggata aagaaaatcc ttcagttggc tgaatataga
    42661 tcgttagaac attaggtgga agtgtcgtat cgtcacatgg ttcatcgaca gatgttttga
    42721 atacattaac aggaacttgt ttgaatacga tgttgatccg agtccctttt tcagtcaaac
    42781 gtttgcctgt acgtacatag aaaggaacac ctgaccaacg gaagttatcg atagtgaatt
    42841 tgcctgcgac gaatgtttca gtctctgatt gagcatccac tttgtcttct tcgcgatagc
    42901 ccttgaattg tacaccatcc aattcacctt gagcatattg cccgcgaacg aagttttcta
    42961 acacttcttc ttcgttataa atgcggatag ctttcaatgc tttgatcttt tctgtacgga
    43021 tttctttttc ggaaaatgct actggcggtt ccattgcaag taatgctaca acctgtaaaa
    43081 tatgattttg caccatgtct ttaagtgcgc cactatgatc gtagtagccc ccgcgatctt
    43141 ctacaccgag gttttcgcca aaagtaattt ggatattgtc gatatagcga ttgttccatt
    43201 gagcctcaaa aatattattg gcaaaacgga tagctgagat gttttggatc atttcttttc
    43261 ctaaataatg atcaatcctg aaaatatctt gttctgggaa tacttctctg atttgctggt
    43321 tcaattcaaa agcagactgg taatcagaac cgaacggttt ttctatgatc aaacgattga
    43381 agccattttt tgtcataata ttttgtgatt tcaaatgaga aacgatcgtt ccaaaaaatt
    43441 gaggtgccat agccaaataa tagacacggt taccgtttaa ttgatagtgt ccatctaatc
    43501 ggtcagacaa ttcttttaat gtctgataat gcgttgaatc atttacatca tgggattgat
    43561 agtaaaaatg gcttgcaaag gtagttgctt cttcatctga aggattcaat gcacggattg
    43621 tttctttgac aacttcacgg tagtgctcat cgctccaggg acggcgagcg gttccgatta
    43681 cagcaaaatg ctcgcctaaa tttccttttc tgtaaaggcg gaacaaagac gggtacaatt
    43741 tacgctgggc taggtcacct gtaccgccga atatcgtaaa caatacattt ttttcattag
    43801 acatgtggat acactccttt atattttatc gacaaaaatc gtgctggccg ccttaaagct
    43861 gacggggatt ttctttctat cattttggat agtgatcggt ccttcataag ctgcgatgtc
    43921 aacgatctca tattcttcgt tgatattcag gtcaatagtg actaagtaat ccaacaattc
    43981 tttttcatca agcactcgtg cgatacgcac ttttgtaccg acaggatagg actccaatgt
    44041 ttgtcggcgt tcttcatgga caacttcctc ttttttagga atcgatcctc catgaggaca
    44101 atgttcagga tgattcaaat agttttctaa atgatctgca agatgttccg aagtcacatg
    44161 ttccaatact tcagcatcat catggacttc attccagcta tagtctaaat gttcaactaa
    44221 aaaaacttcc cataagcgat gtttgcgaat cagactgcta gctttttgca gtccgcttgc
    44281 agtcaattgt acaccttgat aaggggaatg ttctacaagc tcttctttca caagtttaga
    44341 aatcatttca ctgacagatg cagctgagac atctagacta gatacgattt gtttattgtt
    44401 gactttcgtt gtatctccac ctagttctaa aatgattttc aaataatctt ctcgatttgg
    44461 tgtcatattc gatcatcctt tcatggtaaa aaaccatcat tagtaagtgt aacaaaaaaa
    44521 acgttaattg actatttttc taaataaaaa acaaaggatt tttagacgtt tttacaacaa
    44581 aaaacgaaag atgatagaga agactcattc tttcgtttat aaaggatata tatatacatt
    44641 gggagggatc tatttttcag ataacaactt atatgaagtg tctgcagatt cgtcataaag
    44701 agtttgttcg ggataagaaa agataagata aaaaccatac tgatcacgta cgactaaacg
    44761 atattcatct atttctacca cagatgtgcc aagagactga ccgttgatca aaaacgtgta
    44821 atcagatgta atctgtaatt gttgtttttg ctggctatca ctaaagaacc atgtaccttg
    44881 atactttgag agtccttctg acttttccgc ttgttttttc tttttcaagt aaataaaact
    44941 tgagagaacg gtaatgagtg aaccaagaaa atagatcatt ttttttatca ccaaatcacc
    45001 cctttatgag aaaataatcg catagacata ttctttcttc tttatttcat tgtaccgaat
    45061 aaaagctaaa atttctctaa gactttcgac tggttttttt actgtttttc tacaaattat
    45121 gataggatac atagtaggaa gaaaggtgac ataatttgaa gtatcagcaa gtggaaatag
    45181 ctttttttat tgaccgcccg aatcggttta tagcacattg tatgaaaaaa gacggagaaa
    45241 taattattgc gcatgtcaaa aatacaggta gaggaaaaga ggtcctgata ccaggcgctg
    45301 aagtggctat tgtatttgct cctggaccta aacggaaaac cgcctatgat ctgattgctg
    45361 taaaaaagaa gggtgactgg tttaatatcg atagtcaatt gcctaatcgg ctggcaattg
    45421 atggtatttt agacggcacg atccttttac caggattaac tggtccattt acggtataca
    45481 agcgtgaagt aacttatctt cactccaaat ttgatattta tttagagacg gtggtcggac
    45541 aaaaagcatt tgttgaagtc aaaggtatga cacttgaaaa taaagcgatt ggtgcttttc
    45601 ctgatgcgcc cacactcaga ggattgaaac atataggaga attaacgtat gccgcacaag
    45661 atggttatgc cgcttatgtc ttgtttattg ctcagttcga acatcttcat ctggcaacga
    45721 tccatgaaga aatgcaacca gcactagctg atatggttcg acatgcgcag caaagcggag
    45781 ttcaaatcct cgcctataat tgtcaagtat cggcagatga ggtaactgtc aagcaggcca
    45841 ttccatttga tgtagatatc ccttttgaag atcctataca atagaaagaa ggtaaaataa
    45901 tgatcaactt aggtattatc ggaacaaatt ggattactca tcaatttgtc caagcagctt
    45961 taagcacaaa aaaatatgaa ttgacagcgg tatattctag acatttggaa aaagcacagg
    46021 aatttggttc tcattatgaa ggggatatcg aattcgcaac agatttgaag acttttttca
    46081 atattactca tatggacacc atttatattg cttctccgaa tagtcttcac tttagtcaag
    46141 ctaagcaagc aattttggca ggaaaaaatg tgatagttga aaagccagct ttttcgacgc
    46201 caaaagaaat ggatgaaatc atccatttgg caaatgaaca caatgtgtat ttttttgaag
    46261 cagcaagaaa tatccatgaa tcaggtttta aaaagattgc cgattactta ccattaaaag
    46321 acgagataat cggtgcaaat ttcagctata tgaaatattc ttcgcgctat gaccaagtat
    46381 tagatggaga agaaccgaat atcttctcga ctcatttctc aggtggtgca ttgatggatt
    46441 taggtgttta ccttgtatat gcagctgttg cttggtttgg aatgccaaaa gaagtccatt
    46501 atttcccaag aaagatttct actggtgtag atggtcttgg atgggggatc ttacgttatg
    46561 agaattttga tgtatcgatc cagccaggta aaatcggtga ttcttattta ccgtcagaga
    46621 tttattttga ctcaggaacg ctagtgatga atggagtcaa tgcaattgaa caagcacaat
    46681 ttcatgatcg cgcgcataaa gaaatcattg atttggcggt aacagctgca gaaaatccaa
    46741 tggcagatga agcagaggat tttgccaatg tcatggctca tccgaaagat ccagcttggg
    46801 gattgttgta tgaagagtgg atcgagctag ctagaaatgt gaaccaagtg atttatgatt
    46861 taagaaaaaa tggcggcatc aaattcgatg cagataatga ggaagatttt taatgaacga
    46921 atttgtacaa gtatttcccg aaaattggca gaaaaaatat gaggataaag ggtttatctc
    46981 accttctctt attcaacgag cagtttttca gccactaagt aataaacaaa gtatagtagc
    47041 ggtttctcct acaggttcag gtaaaacact ggcttatctt tggcctctac tactaaacgt
    47101 ggaaccaggt gaagcaagtg cgttggtcat ttttgcttct tctcaagaac tagctattca
    47161 agtagcagat gttgcacgtg aatggggaaa agacaaagag ttgaaagtcc aatctttggt
    47221 gggcggagcc aacgtcaaac gtcagattga gggtttgaag gaaaaaccag aaatcttgat
    47281 tggtacacca ggaagaatat tggaattgat gaaagcaaaa aaaataaaag cacatcaagt
    47341 gaaaacaatg gtatttgatg aagcagacca gctatttgac gctgggaaca gccaaatcat
    47401 tgatcaaatt cttcatcaag ctccaacaga gtatcagcta gctttttttt cagcgacagc
    47461 agatcgttcc cttgaaagca ttgaaaaaat cactgggaaa acgtttgaga caattgacgt
    47521 gacagcagag gacgattctc gaaaaggact gagacattac tttttacgtg taccgatacg
    47581 aaagaaagat gactacttga gacgtctcac gcatatagaa gattttcatg gtctgatttt
    47641 ctttaatcaa ctgactgaat taggcgtaat ggaagaaaaa ttgctgtata gaggtgtacc
    47701 ggtaggaagt ctggcctctg atcagaacaa gctactccga aaagcagcgc tagaacaatt
    47761 caaaaagaaa atggtcagag cacttttgac cacagatgtg gcggctagag gtttagatat
    47821 tacaggtctt ccttatgtag tgaatgcaga agttccgtta agtgaagaag cttatttgca
    47881 tcgttcggga agaactggtc gaatgggtaa tgaaggaata gtaattacac tcgtacaaga
    47941 taataatcta agagatttaa aacggctttt acgtccatca aatataacac ttgaagagat
    48001 ttttttatac ggaggtaagc tgcaaactga gcagccaacc aaagaagatg cagctcctgc
    48061 agtaaataaa aagtatgcga aaactttttc tggaaaggag cagaacccag aatataacaa
    48121 agaaaaaata agaaaaaaag ttaaaaataa atcaaaaaaa gagagaaata aaggagcaag
    48181 gcgcaaataa gcgccttttt atgctatgat tatgaaaacg ggaacaaaat tggttgccag
    48241 aggaggggtt atgtgaaaga acgtcaagaa gagatcttgc agctattgac agaaaaccaa
    48301 caaggattga cagcaagtga tgtagctgag cgcttaacta tcgatcgaag caatgcaagc
    48361 cgatatttaa gtgaactata caaggcccat catattgtaa aaaccgctgg ccgaccagtc
    48421 gtttactctt tgccaacgga aaagtcaaaa tctgatgaag tgcatgtcga ctcttctacg
    48481 caagtgactt ttgaaacact cgttggagaa aatgattctt taaaagtcag catacagcag
    48541 gcaaaagctg cgattcttta tccaccgcgg gggttgcata cgattatttt tggagaaact
    48601 ggtacaggga agtcgatgtt tgctgaatgt atgtatcatt ttgcaatcga ttcagagatg
    48661 ctttctgcag atgcgccatt tgtttctttc aattgtgcgg attatgctca aaatccgcaa
    48721 ctgctctttg gacacatctt tgggatcaaa aaaggggctt acacaggagc agctcaagat
    48781 agtcccggtc taatagccaa agcagacggc ggtatattgt ttttagatga gatccaccgt
    48841 ttaccgccgg aagggcagga aatgctgttt actttcattg ataaaggtat ttaccgtccg
    48901 cttggagaaa gtgcacaagt acatgaagca tctgttcaga tcattggggc gacgactgaa
    48961 tcttcagaaa gtttcttatc tacgttcaat cgacggattc ctatggcaat caccttgccg
    49021 aatcttgctt cacgttcact ggatgagcgt tatgaaatca tctctctttt tatcaaacaa
    49081 gaagcgaatc gtttgaatca acgtatcgat atcgaaaaag aagcgattct tgccttcatg
    49141 ctttatgatg cggaaggaaa tatcggtcaa gtgaaacgag acttgaaact agtctgtgca
    49201 aaatcttttt tacattaccg tactcatcat gagaaaaagc taatcattcg aaaagaagaa
    49261 ctttcccttc aagtacaaaa aggattactg aaaatcaagg aaataccgga acgtctcgac
    49321 cgattcatgg acagcaaaag tcagtatttg acatttgaac caggatttgc tgatgttgtc
    49381 tggtcacaag atccagaacg aaacatgcag gtctataacg atattgagga aaaagtcact
    49441 tctctttccg aaaccggtgt ggagaacatt gatctagaga ccctcatttc aaaagatgtg
    49501 gatgcttatt tccagacata tgtcaaagaa ttgactaaaa gttcgattcc caaagatctt
    49561 ttgccagatg aaatctggcg gttaaccaat caattgtatg atgtggctga aaaacggtta
    49621 gaccgtattt ataatgaaaa agctcgtttt gcttttgctt tgcatctgca aagtacattg
    49681 gatcgtgtga gagaaggtca tatgatcgtc cacccagatt tgaataacgt acggaaaaat
    49741 tttaagaggg aattccaggt agcaatcgat ctttcaacga tcattgaaga agaagaacaa
    49801 gttgagattc cttttgatga aatcggcttt attagtatgt ttctttctat caatctagga
    49861 gaaagtgagc ctgttaaaga aaacaaagta gatgttctca tattgatgca cggcagacag
    49921 actgcttcaa gcatgttgga gatggcacaa gaactattag gaacaaaagt agggaaagct
    49981 tttaatatgc cactggttat ggaagttcaa acaatgtatg aagaagtgtt acaatatgtc
    50041 aaaaactatc aagagcattt gacgaatggc ctactcttgt taacagatat gggatcatta
    50101 aacaccttca gtgatttgat ttatgaagag actggcattc ggacgaaagc tatcacgatg
    50161 acaagtacca tgattgtgat agaagcgata cggatggcaa gtgttggaag aagcttagaa
    50221 gatatttatc aaaatatcca gctttccttt gaatcgatcg tacgtgatca gttcaaagcg
    50281 gaaaagtctg aaactttaca gcgtaaaaaa gccgtaatcg tgacatgctt tactggtgaa
    50341 ggagtagctg ccaaattata tcagcgtatt atgccagtga ttaatcaaaa taaggtagaa
    50401 ctgatccaga tgcagttttt agaacgtgaa tcattcaaaa aacacatcga tgccttattg
    50461 gaagaatatg agatcaaagc aattgcggga acagttgatg ttgattatca aaatatccca
    50521 tttttttcag cctatgacgt ttttgatgat gaaaaactaa atattttaaa gcgtatagct
    50581 gatgatgaga tcccgacagc taaaattgtc gattcacttg ctggatcatt aagcgatgtc
    50641 ttttctattg atgaactgat ccgttcattg caaaagacag ttcagcagat ccagaccgat
    50701 ttgtcgatta tcgtggaacc tggagtagat actggaatcg ttatccattt agccttcatg
    50761 ttagacggat tgatcaaaca agaaagccat cggcaatttg agaaactgtc tattttctca
    50821 aaaatttatc gtttggaaat ggatatcgtt cgggcaaact tgatggcact agaacgaaaa
    50881 tatcaggtaa aaattccaga agatgatatc gcatttctta cacaaatgtt tcttgaaaat
    50941 aaaataaaaa aatgaacaca ctaatcatac tgtttacaca ctaaacatct gtgtgcgcac
    51001 tataaaaaag agctaaaaag catgaaaacg ctatttcagc tctttttttt attggcatgc
    51061 ttcttgcgtt atataaaagt gtaaaaaaat aaaaggagtg ttaaaaatgg caaaaaaaac
    51121 aatcatgtta gtttgttcag cagggatgag tacgagttta ttggtcacaa aaatgcaaaa
    51181 agcagcagaa gaaaaaggga tggaagccga tatttttgcg gtctctgcct cagatgcaga
    51241 taataattta gaatctaaga atgtcgatgt attattatta ggtcctcaag tacgtttcat
    51301 gaaagctcaa tttgaacaaa aacttgcgcc taaaggtatt ccattagatg tcatcaatat
    51361 gcaagactat ggcatgatga acggagaaaa agttcttgca caagcagaaa atctaatgaa
    51421 ataaatcaag tatgcagttg ggggtataac aacgtggaag atcaacaaaa tctagaagcc
    51481 atcatggggt taatcatgtt tggcggtaat gcaaagagcg atgcaatgga agcgattgcg
    51541 gctgctaaaa tcggtgattt tgagttagcg gataggaaaa tcgctgatgc agaagaatca
    51601 cttatacaag cgcatcatgc acaaacagac atgttgacac aagaagcaca aggaaatcat
    51661 atgcaagtga cattattgac tgttcacagt caagatcact taatgacatc tattgcgttt
    51721 actgatttag caaaagaaat catcgaactt tatcgtcgcg tatacagcga ataaatacaa
    51781 cttctttttt gaacggaaga agaaaaattt ttgaacggat tttttatttt gttataagga
    51841 gaactctctt tatataaaaa acttatagga ggaagtaaaa aatgaacgga ctatcaagtt
    51901 ggatggagaa atacatcctg ccggttgccg caaaaatcgg agcgcaaaaa catttagttg
    51961 ctttgcgtga tgcttttatc ggcacactgc ccgcaacaat ggcgggatca gtcgctgtaa
    52021 tgatcaatgc aattattcgt gatttaccgc aacagtttaa cagtacctat gctgacagtt
    52081 tagcagcaga caaaggaatc tttgccgtat tgaatgtcat catcggaatc aatggttttg
    52141 tctggaacgg tacactagca atcgccggat tgatctttgc cttttcttgg gggtataatc
    52201 ttgcccgagc ttatggagta aatgatctag ctggggggat cgttggttta gctaccttga
    52261 ttcaaggtat ttcctttggt ccagcattat cagcagcatt agatgtgaat gttccttcaa
    52321 atgtcgcaga tgcaatcaat agttctgaga ttggtgcaac gattgcagat ggcacactgt
    52381 cagttggatt atggggttgg ctaaaactag atcatttgaa tggaaacgct tattttacag
    52441 ttatgatcat gggagctatt tcagtcatta ttttttgtaa attgatgctt gccaacatta
    52501 cgatcaaaat gcctgattca gtaccaccag cagtatctaa agcatttgca gccattttac
    52561 cagcgacgat cgctttatac gtcattgcta ttatcaatta tatcgtaggt cgtgtagctg
    52621 atgggcaact gatcattgat ttggtgcaaa aatatattgc agaaccattc ctaggattat
    52681 ctcaagggtt gggagcagta ttgatcgtca cagtatttgt tcaagtattc tggttctttg
    52741 gtattcatgg accaaatgta ttggcaccag tgctagaggg aatctgggga caagcacaac
    52801 taatcaatat tgatattttc caaaaaggtt ataacggaaa aactggtaca ccagccgtgt
    52861 tagatgcaat cgaagatgga aaagcttata tgtgggtccg cggatcgttc gatgcttttg
    52921 catggtttgg cggatcaggc ggaacgatcg tcttactgat agctatcttg attttctcta
    52981 aacgtgcaga ttatctaaca gtagctaaat tatccattgg gcctggtatc ttcaatatca
    53041 acgaaccagt gatgtttggt ctgccaatcg tattgaatgc aatcatgttt atcccattct
    53101 tgattgctcc agtagtagca acagcaattg gatggacagc tacttatctt ggcctagtcg
    53161 ctccggtatc gcagcaagtc acatgggtag taccgccgtt cttattgtca ttcttagcaa
    53221 caggagcgga ttggcgggca ccgatcgtaa cattagtatg tatggtcgtg actttcttga
    53281 tttgggcacc atttgtcatc tctgcaaaca aaatggaccc tgccgcaggc gaacaacaat
    53341 aagatgaacg tgaggagcgg gacgctttaa gtttcgttcc tcataatgaa ttttcgagga
    53401 ggaactgaaa tgattacaat tgccagtgca atgcaacaag atgaaatcaa agaattgtta
    53461 gaaggataca atgaagaagg aatgactttt acatttaaag aaaaacaagg aatcaagctg
    53521 ttctttgaaa caagtgcaga agatccggaa gttgcggcta aaaaagcaaa ggaactaatc
    53581 aaagcacagc cttggggaac agtcctttat tttcaatcaa cagctgttta gaaaatggtt
    53641 taaaaagata ggatggttga gatgataaaa aacggtttat ttttatgtag tattggttct
    53701 ttgatcgtgt tgtatagttt gaatccacat tcgcaaaggt atgatttgta tagtatggtc
    53761 acaggtcttt ttctaacagg attaggaatc tatttcttca tgaaggggaa aaaaagagaa
    53821 gaagcaaagg agaaaaataa ctaatggaaa tcacgaaaaa attaaatatt ccagcatcgt
    53881 ttttttacga taaagttatg gactctgtcc ttttcgatgt acgtaaagcg accggcaaat
    53941 cagtaactag aaaacagctg aaaaatttgg agtacgtcaa acaattctcg caaaataacc
    54001 gggctcgcat aaaaatcgaa gaagtcattg aaaaccagtc ttataagttt cgtacatcga
    54061 caacgaagaa tgaattcgtc gttcattatc aaatcaaacc attggacgat tcgacctgtg
    54121 aggttcatta cacagaaaaa atggagtctt atggcatgct tcaaaagttg aatgatatgc
    54181 ttttaggaac aatcttgatg tattttaaac ggagacgttt caaaaaaatg ctagatatga
    54241 tcgaagcaac gtattaaatc aatgaaacat ggtactattt agttattgaa aaatgaagta
    54301 agctagaagg aatttttcat aggaagatag atctttcctg cgaatcctca ctagcttttt
    54361 tgtaggaagg ggcagcaaaa tgacaaacaa agtaagagag ctaggtgtat cttcgattga
    54421 ggaaatgttt gatttagcca cttatgcatt taatggggca gatacacctg aaaggcgaga
    54481 acgttttcgt acacttgcgg agaattcttg gaattacgga ttttttgatg aggaggatcg
    54541 gctaacaagt caagtcatgg cgaccccttt tccagtgaat ttttacggac aagagtacct
    54601 aatggccggc attggctatg ttgcttctta tccagaagca aggggacaag gcgggatcaa
    54661 tcagatcatg gaaaagatcc ttgaagattg ccgtgatcgt aaagtaagct tatcttatct
    54721 ggcgccattc tcctatccct tctatcggcg ctatggctat gaacaatcat ttgataaaat
    54781 cagttatcaa ctaaacagtc gtgatgtgcc gtttatcaaa aaaaaatctg gaaaaataaa
    54841 gcgtatggat tttgaagatg caaaagctgc aatcagaaga atttatgaac agatgccgga
    54901 aaaccaacga gctggtctga agcgcgaaga ctggtggtat acgtataaat tcaagcaaaa
    54961 aggcaattac cagtttgctt tgcattttga tgataatgag gaagcaacgg gatatatcgt
    55021 ttatcagctt gcaacgtctt cctttattat tgcggagtgg ggatttttgg atcatgatgc
    55081 tttttgcagc cttgttcgct tcgtaagttc tcacaatggt gcttttgaaa catttgaata
    55141 ttcatgcggc tacggcggta atgatcaaaa ttatctatta gaaaatccat ttgcttctgt
    55201 aatgatcaca ccttatatga tggcgaggat cgtagatatt tctttgtttt tggaaaatta
    55261 tccatttaaa aagagacaag ctgcatttgc cctacaaata gaagaagatc attatgcgaa
    55321 atggaatgaa ggaatcgtgg aagtaacaat cgaaaatgga aaaaatcatc tctcaaaagt
    55381 agaacaaaca aaactcccaa tcgttcgagg aagtatccaa catatcacgc agctattatt
    55441 agggtatcgt aaagtggaag agttggtatt ccaagaaaga atacaggtga caaaagaata
    55501 tgaagaaacg ttaagctcaa tcttgccaca gcaacagcca attcttaatg actatttttg
    55561 ataaaaaacg ggtgatgaca atatttttgt caccaccctt ttgtttttca tttggcattt
    55621 gaaggaaaat gttaaagtaa atcctctttt ttcgtaaatt tgaatttttt gttttctttt
    55681 gttttagggt tttctttttt gtggtcttgg attgcttctt tcgtaatctt ttcccgattt
    55741 tttttagatg aatctaagcg ttctgcgtat actttttctt ttggcttatc attcattgga
    55801 aaggacctcc ctacattatt tcattctacc tctagtttat catctgttaa ggactagtgg
    55861 aaacgttttg cctaacttat aagctgattt ttttagcaga taagcttgca agtaaaaaac
    55921 aaacaagcta caattgattt attgaaattg ttcctgtagc tcagtaggat agagcaatcg
    55981 cctcctaagc gataggtcgc tggttcaatt ccagtcagga acgtataaat aacccctgta
    56041 tcctttgcgg tacaggggtt tgttttgtat ttgtgccaaa aatgtgccaa actagttatc
    56101 atttttatat aaactatcga acacagtatt gattttttct ttatcctgat cttcaagctc
    56161 tcgaacaata tgaagataag tagacattgt agtttctaaa ctgctatgtc ctaaacgttt
    56221 cgatacgcta agtatattta ctccttgata aagtaaaata gatgcatgtg tatgccttag
    56281 tccatgcaaa gtaaattgct tttcaatccc taattctttt aattttttgc gcaaatattt
    56341 gctgacggcg tttgatgaaa ctaatccatt ttttaagttg aaaaaaacaa aattatgagg
    56401 gtttttgatt tcaaaattct cgaataattc tttttgattg attttaaact tttttaagag
    56461 atcaatcgta tgtttatcaa tggaaatttt cctatttgaa gtttcgtttt ttgtttttcc
    56521 ccattcattt aatttataat tccatgtttt attaatagtg atgatttgat cttcgaaatc
    56581 gatatcttcc catgttaatc ctagaagttc agcaaatcgc attccagtgg caccagcaac
    56641 taacacgagc ataggagaag agtactgcgc agaaaggttt tcttctacga gtttcattaa
    56701 agatttaaat tgatcataat ctaaatattt atcttctttt ggcttcaatg aatcttttcc
    56761 tttgattact gcttttctag ttggatcaaa cggaattaat ccttcttcta cggcatcttt
    56821 caacgacgct ctaatatggt tattaaactt aataacggta gattttacat ggtctttagc
    56881 atacttattt aaaaagcgtt gatatcccac tctatctaaa tcagaaatca ataccgctgg
    56941 catatatttc tttatgttca ttaacgtatc ttcgtatttt ctataagtga taggagatac
    57001 tgttccttct ttataaagtt gcatccaatc ctcaaagtaa tctgataata atagattttt
    57061 gcgatcccct ttaaggcctt tgttcaagtt atattctaat tcgttggcgg catcttttgc
    57121 ttctcctttt gtcttaaatc ctgattttct tatcttcgtg tattttccgt catctttttt
    57181 gtatgaaatt tcgtattgcc aactatttcc acgtttgact aatcttgcca taattgaatc
    57241 agctctcttt ctctgataca ataggaacta taaagaagcc cattgtttgg gttttattat
    57301 tttttgcaca tcctttttgc ttgccggcgc aaggatgtgc tatttgtcgt tttaatggta
    57361 taattggatg tgtattagat catccaatca gaggtgttta ttatgattaa agtgattttt
    57421 aaaagaataa ctgaacttcc agagtttaga ttatttgttg attattggta tgtctggttt
    57481 tttattgttg cattgctgat aggtctagat gtcatattag aaagaaaact taagtaagag
    57541 ttgagttaat aaattgaatt cctaaatgag atattttgta gcccatattt tgtttgccga
    57601 catcacctaa tactatggag ctaatcgttt tttctaacag accaaaatca gataatctat
    57661 ttaagctacc atctattagc tcttgtgaat agccagacat gctgatattt ccagtgaaat
    57721 tttcgtttcc acgactcatt aagcatgcta acaattgaat ctcaatcgat gttaattgat
    57781 tcagtacaag aagataatac tcctcgttat cccatgaagc gttgttaatt cgaagtaaac
    57841 aattcttata aagattttta tacatatcta ttttattttg tgcctttgat ttttctacct
    57901 cgtcatttat cccttcgaat attccaatga gttggtcctt gttctctaag ttgaaaacat
    57961 cttctggaat ttgatcgcga atgttttcta atgattcgtt taaatttttg tagaatttct
    58021 cgatgcgttt gaaacgcttc tcgtttttag acccaaaata aagtgactgc acaacgccac
    58081 caatataagg aattgctcca ataccgcctt caactattaa ttcaagatat tcttttttgg
    58141 ttagtttttc attgctatta tccatagtta cctcctattt tgtcatttcc tttacaagca
    58201 ttgtgactcc tgatggcact cttttgtata ggttttatta ttgtgcacaa tctaactctt
    58261 agtggggcgt ggttcattta ttttttactt actttactat taatcatatc ccattgagca
    58321 taggattttt ctatgttcga tcctcttgaa ctaatttctc ctgtaaaagt tactttatcg
    58381 ccctttgtaa aggtatcagc attgtttaag tccttcgcaa aaattacata tgaaacttta
    58441 ggtgttgcag aaatatcatt ccaactttta tcatcgtact ctttgtctgc tataatggct
    58501 attctagtag tcattgattc gataacagtt ccttcaaaag tatatgtttt accactaata
    58561 tatttagtaa aagctgtatt ttgctcagta gctggagtaa tagaataata actatctaag
    58621 aaagcacccc agtcatgatt atttgtctct aaaaattctt caaattgagt taggctttta
    58681 ttgctgctgt tagatgtagt agtttgagta tcagatgatg agctttcctg tttgttattg
    58741 tcatttgcct cgtttgatga ggaaagcgag aaacctacgg tagtaaaaat aatcccgata
    58801 ataaggagaa tcataggtgt tttcttattt gtttttttga taaatcttac aattaacatg
    58861 attaaaccta taataaataa aacaatacca gtaaaaccaa atataccgtc cattaataga
    58921 tcctctttct cttttgatat tgaatattat aaaccaagca attctttttt cttaaaatcg
    58981 aattcttctt gattaataat cccttcatct aacaactctt tatacttttt aatttcatct
    59041 gcacttgaaa tttgtgtttc tttggaatta ttatctaata tagattgttg cttctctata
    59101 tattttttta aattttccat ttcattccaa tatttttttg taaacataac ggtgttttca
    59161 tctttcgtgg ccgctaatat acctccgcga ctttcgtttc cgcctagcaa ggtaaattgt
    59221 atataaccat tactcatacc tggttttttt aattgtacgg ctgatatatt tttaaagggg
    59281 atagtttttt ctcctttaat accttgatta actaaattta taaatccttt tctaataatt
    59341 gaaatagaat catcagttac tttaatcaag gtttttcctg gagattttat taaaatctct
    59401 ttttccattt tttcttcctc atttctgtga tatgattttt tttgtagaag ctcatatatg
    59461 aggaaagagc ccgtgttgca gcacgggctt ttttaatgtt ttgctgaaat cggttttttt
    59521 aataattctt gatgtattca tacatattgc cttgcgtaag aatatttttt cttaaaatag
    59581 cattggcaga cagcataaca agtgtatctg agcttattct gaatagaata atactccata
    59641 aatttttcga gattaaactg agattcatca gtcagttcgt tctcaatata gatatttaat
    59701 aaaattagaa tagctatttt atctgcttct gtttcaaatt ttgagtgaaa agttgtagaa
    59761 gtatcgtaca aaactgaaaa ttcaaaatga gaggcgctga aatgtgcaag ttcatgagat
    59821 aaatgaaagg cttctgcagt ttcaccgtat agattttcat tcaaaaaaat gattctgggt
    59881 tttggatagt agaaaccagg ctctttcatc tccatataaa ctactttcaa attgtattcg
    59941 ctcaacattt ctttcaattt caaatacata caaaccatca ctccaactat tcattttcct
    60001 ctaaagcttt agcaattgca atcgctttac gcattgtctc cttagatatt tcttttccat
    60061 caaaagaaaa aacagtatcg tcttctgata aatccacatg tttaggggtt tctctttctt
    60121 ctctacctag aaggtagtct acagagacat cgaaatagtc agcaatccga cttaattcat
    60181 ctgaattagg agtattattt ttccactttg ctagataacc gttagaatat ccaaaattaa
    60241 tttctaactg ccgtatagat atctttttcc tcttcgccaa gtcttttatt atttcatagg
    60301 tattcatcga taaaacaacc tttctaaatg tttacaaaaa aagtttagaa aaatacgcag
    60361 aaataatttg actaattctg agtaatgagc tatactatat cttgtaaaca gatttaacaa
    60421 ctaaaaagac aacaaaaaac actattgata tgtaaatgca gaccgccaag aaagctttaa
    60481 aatcaatgtt tttatgtctt atttaattat gctcttagta tagagtatta ctcagatact
    60541 gtcaattgaa tttagaaaaa agttgttaaa tttgtttacg aatataaaag aaaggaatga
    60601 gaaatatgaa cacaccgcaa atttttaatt tcgaacaaaa cgaagttcgg acaattttag
    60661 taaatgatga accatatttt gtaggcaaag acgttgcgag tgttttgggt tattcaaaca
    60721 ctaaagatgc tttgtcgcgg catgtagatt tggaagataa gatggggtcg cgaatcacga
    60781 cctcaggtca atcaagagag atgacaatca tcaacgaatc tggtttgtac agtttaatct
    60841 taaaatcaaa acttccctct gccaaaaaat ttaaacgttg ggtaacaagt gaagtgttgc
    60901 cagcaattag aaaacatgga ggttatctaa ctccagaaaa agtagaagaa gctttgctta
    60961 atccagatac aatcattcaa ttagcaactc aactaaaaga agaaagaact ggaagattaa
    61021 tcgcagaaca aaagattgca gagtacgaac ctaaaatctc ctatttagat agcatattat
    61081 cttctacaga ttcagtaaca attagtcaga ttgcagcaga ttatgggatg tctccacaac
    61141 agatgaataa attacttcat aaactaggta ttcagaaaaa agtcggtaac caatggttat
    61201 tgtgcaaaaa acacatgaac caaggataca caaaatctca tacaactgag atcccgaaag
    61261 ccgatggtgg cactaaaatt gtaatgaata ccaaatggac acagaaaggg cgtctattta
    61321 tctacgaatt actaaaaaaa gaaggatatt accctcaaat ggatttagag gaaattggtt
    61381 agaaaggagt tttagtatga ctgacattgc agaaatcact caacgagata gagaaaaaat
    61441 caaagaatat gtcgaaagtt caaagttctt aacttacacc atgcttgctg aaagatttgg
    61501 aattagcaaa agctacttat ctttaatttt aaacggtaaa aagacttctg cagaagcaaa
    61561 cagaattata gattcgatta tcactatgta cgaattgtaa agggaggaac agctaatgca
    61621 atatctagaa gcaaaaatcc caattccaga aggctatgta attatctccc aagtggatta
    61681 tgaggagtta aaaaaagctg atgatactgg tagatggatg acgttgccag aagtgctaga
    61741 acggattaac agaaaatatg attggtttac ttctagagtt ttaaagaacc caagatatag
    61801 aaatattatc gatatcgaga aaaacaaaaa tggatttgtc tattatccag ttgaaggaag
    61861 agacacatat ctatttttaa gaagtaaaac acttgaattt ttagaaacaa atttttcgga
    61921 aatcttaagg aggtaagcgg atgggtaaat ttaatagagc actagtattc agcgcaccac
    61981 taattatcta cgctttaggt ctttggggaa gcagacaagc attaatcggc acaattgtat
    62041 atatggtctg gatctttatg gggcttgatg aagctgaata tagagcgaaa aagccagtcg
    62101 ggagggactg acttaaccta attaattaaa aattgtaaca aataacgcaa aaataaagct
    62161 aatgaaattg tattgttagg atctactcca atagttatat ttacaatttc ggttactact
    62221 agtcctatca aagctgcccc agtttgctct aaataccaca ttttatcttt gtagaaagca
    62281 ggtgaagctt gttgtttttc agatggttca ttagttatat ctttgttctt ggctgtattt
    62341 atttcttcaa aaagctttat agaatcatca aggactttcc tttgctcatt aaggatatca
    62401 aaaaacttag cctcaaactc atcagatgga ttagaagtgt ctttaaaaag tagatttttt
    62461 gtactaactt ccggttcgga agaaaatgct ttttctaatt cttgggtagc tacccctatt
    62521 ctgaagtcgt acttagacat gtcaacggca aatttttctg tgattttaga gatatcagaa
    62581 aaataaggtt ttggcatagt agctgccatt tttttagcaa tattaaaact tggagattct
    62641 aattgtttct gtattgcgaa caaagaagga ggaatcatat tagcaataga tttgttacgt
    62701 ttctcgacaa tttgaatgag agaatcattg agtattgctt gcgaagctat aaaagtatct
    62761 tgaattgcaa ttaatttttt agcttgttct atcgcaggct gcatagcgtt aacgacatct
    62821 agagaaggag caatggtttc accgattaat tttgaagaag ctatcaattt ttgataataa
    62881 ggagtatctg aaatatccaa ttatatacac caccttttta cctaaattat accaaaaggg
    62941 agagaaaaaa atgcaataat tagtaatttt gaaaaataaa gaagctgtga ctacgagctt
    63001 acaagtcgca gaaacattcc gaaaggaaca tagagcagtt ttaaaggcga ttgacgatct
    63061 aaaagatggg cttgcacaaa agtatgcaga cctattttgg gaagatgtgt acatccatcc
    63121 gcaaaacaaa caggcttatc gaattgtcta tatgaatcgt gatggcttta ctcttgctgt
    63181 attaggattc aacaatactc aaaaagtttt agagttcaaa ttgaaataca ttgaagcgtt
    63241 caacgaaatg gaaaaggcaa ttcgcaaaaa tacagctttt gacacaattg aagacatgat
    63301 gatctatcaa ttagaagaaa tgaaagatgt taaaaaagat gtttccatgc ttaaaaatac
    63361 tatgcgaatt agcggacaac aagagtttga aattaagcaa aaaggaaata cgaaagttat
    63421 ggaagttcta gggggaaaag aaagccgagc ttatgaagaa atcagcaaaa aagtattctc
    63481 aaaattttgg tctgaattta aacgtacctt ttcaatccca agatatggcg agttacctcg
    63541 taagagattc gatgatgctg tttcatttat tgaaatgtgg ttaccagaaa ctgcgattcg
    63601 catggaaatc gatcaactga acagacaaca aagacttttt ggtgatgaaa atgaatagag
    63661 ctgaagcgct aagaatcggg acggtaattg ctaatcgctg gtggagacac aataaaccaa
    63721 tcatcctaag ccaacaacat attgacaagc aaaaagcatg gcaacaaata aaaaagtgac
    63781 tccgccggca agcaaagagt cacaaagaaa acacatcata aggagatttt agcatatgga
    63841 aaaagaactt tccactctag atcaatattt gactgatcct agttggggca aatcgaatat
    63901 caaggaaaca aataatcgaa aaatcagacg aaatcttttg acggatgaag aactagcatg
    63961 tgatcaagac gatttgggaa attttgtgag tatttgggat catgtctatc ttatccattt
    64021 atcgaggaag tccaaaaaac ctgaatatat ctatgtcatc gaagatggct tgattgatgc
    64081 gctagaagag tatgacagag ataacttgat tgatatctct tattacggat caggtaagaa
    64141 atacattgct gaaatggagg cagaatttga tgagtgaaaa caaagggaca acgacttttg
    64201 aaaaactttt tagtcgcaag ttaaataaaa tactcaagaa aaaaggaaat tttgattatt
    64261 tatcttgggc tcacgcatgg gagattatga aaaagaatga tccacaggca acggtaacta
    64321 ttaatgagta taaacactac agagttgttt ctggaactca tcaagacttt cttgttgagg
    64381 aatataaacc ttttcttatg gatgaaactg ggacttatgt atctgtctca gtaacggtta
    64441 aaggacacac ggaaaccgaa ttatttcctg ttttagatta tcgaaaccaa ccagttgtta
    64501 aaccaaatgc aatgcaaatc aataactcat tgaagcgatg ctttgtgaaa gcattggctc
    64561 tacacggact gggattatat gtatttcaag gggaagatat tccaacacca cctagaatcg
    64621 atacgaagaa attaaacatg ctagagacga ttctagaagc tttcaatgag cagatgggta
    64681 aagatatgac caaaacctta atcgaatatg ttaatgagca gacagataaa ttagggctct
    64741 tagctgataa cgttgaaact attgaacagt taagctatga gcaatgtgcc ttgatggagc
    64801 gagcaatagc agctaagaga aaagaattag ataagaagtg atatgagtgt ttaaaccatt
    64861 aatcgattca tattcagcgg ttctgaaaaa gttcaaagga aaagacatag gtgcaaccat
    64921 caatgaggaa gtgaacattg atcgactaaa gacgatgtat gacggctacg atggtgatcg
    64981 agttattgaa attcgtttta ttgatcctag acgtttcaca gtacagcaac gaaacttcat
    65041 ctatgcactc ataggcgata ttttcatcga tacaggcatg ccaacggact tctggaagga
    65101 attcttttac ttccgctttg aaggtgtcac agggcgcaaa ataagcctca aagatgaatc
    65161 gaatacgact gtgagtgatg ctaacgtctt agcaaatatc atcttagatt tcatctttga
    65221 acatcatatt cctttcaaag aaggctatga gattttacca gcgaatcaag aatattactt
    65281 ctacaaatgc atcacaaaaa gagtctgttg catctgtggc aaaacaggag ctgatatcga
    65341 tcactttgac aaagcgctag gaagacgaaa gcgcaaagaa gttgatcatt cagagtacac
    65401 atttgcagca ctctgcagaa tccatcacac ggagaaacac aagataggtg tgatcaattt
    65461 caaaaataaa tatcaaatca aagggatcaa gttaaaccag gaaacaatta agaaacttag
    65521 aataggagga taaaaaatat tggctgacaa
//
LOCUS       DAZULR010000012        61534 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.012, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000012 DAZULR010000000
VERSION     DAZULR010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 61534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.012"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(59..187)
                     /locus_tag="ACG8ZV_000863"
     CDS             complement(59..187)
                     /locus_tag="ACG8ZV_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HFS4996224.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="ACG8ZV_000864"
     CDS             complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="ACG8ZV_000864"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFS4996225.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(1674..2729)
                     /locus_tag="ACG8ZV_000865"
     CDS             complement(1674..2729)
                     /locus_tag="ACG8ZV_000865"
                     /EC_number="2.7.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HFS4996226.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="ACG8ZV_000866"
     CDS             complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="ACG8ZV_000866"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HFS4996227.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="ACG8ZV_000867"
     CDS             complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="ACG8ZV_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HFS4996228.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKATFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="ACG8ZV_000868"
     CDS             complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="ACG8ZV_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HFS4996229.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="ACG8ZV_000869"
     CDS             complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="ACG8ZV_000869"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HFS4996230.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTVKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="ACG8ZV_000870"
     CDS             complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="ACG8ZV_000870"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HFS4996231.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLANPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            10491..12050
                     /locus_tag="ACG8ZV_000871"
     CDS             10491..12050
                     /locus_tag="ACG8ZV_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HFS4996232.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQKVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(12161..14092)
                     /locus_tag="ACG8ZV_000872"
     CDS             complement(12161..14092)
                     /locus_tag="ACG8ZV_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HFS4996233.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAAAEA"
     gene            complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="ACG8ZV_000873"
     CDS             complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="ACG8ZV_000873"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HFS4996234.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(15021..15773)
                     /locus_tag="ACG8ZV_000874"
     CDS             complement(15021..15773)
                     /locus_tag="ACG8ZV_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFS4996235.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLFNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(15932..16141)
                     /locus_tag="ACG8ZV_000875"
     CDS             complement(15932..16141)
                     /locus_tag="ACG8ZV_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996236.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(16152..17480)
                     /locus_tag="ACG8ZV_000876"
     CDS             complement(16152..17480)
                     /locus_tag="ACG8ZV_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996237.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            17616..17771
                     /locus_tag="ACG8ZV_000877"
     CDS             17616..17771
                     /locus_tag="ACG8ZV_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPJ_0845 family protein"
                     /protein_id="HFS4996238.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(17845..18432)
                     /gene="yihA"
                     /locus_tag="ACG8ZV_000878"
     CDS             complement(17845..18432)
                     /gene="yihA"
                     /locus_tag="ACG8ZV_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HFS4996239.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="ACG8ZV_000879"
     CDS             complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="ACG8ZV_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HFS4996240.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVERAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(20012..21301)
                     /gene="tig"
                     /locus_tag="ACG8ZV_000880"
     CDS             complement(20012..21301)
                     /gene="tig"
                     /locus_tag="ACG8ZV_000880"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HFS4996241.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(21455..22387)
                     /locus_tag="ACG8ZV_000881"
     CDS             complement(21455..22387)
                     /locus_tag="ACG8ZV_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996242.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLNEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(22544..23203)
                     /locus_tag="ACG8ZV_000882"
     CDS             complement(22544..23203)
                     /locus_tag="ACG8ZV_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HFS4996243.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSIYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAIFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="ACG8ZV_000883"
     CDS             complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="ACG8ZV_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HFS4996244.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELASNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAMR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(24244..24534)
                     /locus_tag="ACG8ZV_000884"
     CDS             complement(24244..24534)
                     /locus_tag="ACG8ZV_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996245.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAEAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            24944..26749
                     /gene="glmS"
                     /locus_tag="ACG8ZV_000885"
     CDS             24944..26749
                     /gene="glmS"
                     /locus_tag="ACG8ZV_000885"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HFS4996246.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDSSDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(26821..28176)
                     /gene="glmM"
                     /locus_tag="ACG8ZV_000886"
     CDS             complement(26821..28176)
                     /gene="glmM"
                     /locus_tag="ACG8ZV_000886"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HFS4996247.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICARYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(28200..29369)
                     /locus_tag="ACG8ZV_000887"
     CDS             complement(28200..29369)
                     /locus_tag="ACG8ZV_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HFS4996248.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(29366..30253)
                     /gene="cdaA"
                     /locus_tag="ACG8ZV_000888"
     CDS             complement(29366..30253)
                     /gene="cdaA"
                     /locus_tag="ACG8ZV_000888"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HFS4996249.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="ACG8ZV_000889"
     CDS             complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="ACG8ZV_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HFS4996250.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIVPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPAMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLENANPN
                     LAKALFEKTIQDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARAERRKKMEQATKEKKEK"
     gene            34320..34841
                     /locus_tag="ACG8ZV_000890"
     CDS             34320..34841
                     /locus_tag="ACG8ZV_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HFS4996251.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLSCPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(35540..36105)
                     /locus_tag="ACG8ZV_000891"
                     /pseudo
     CDS             complement(35540..36105)
                     /locus_tag="ACG8ZV_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(36284..36940)
                     /locus_tag="ACG8ZV_000892"
     CDS             complement(36284..36940)
                     /locus_tag="ACG8ZV_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996252.1"
                     /translation="MRFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLRAGLITFIS
                     IVGFFLFTVIVFIWRTPAPPLPEITYGEFPFRLEYELNEELHVIEDTLIVEFDGFGMN
                     EGIGRYRRWTSRLASGEDLVLLLEVSDNKQIFYFPGPANYYMGDRLNGYNHTFPSASF
                     IERERGITRRDILHDKELLEQFGPLDQNTINEEELLNQYNIRLVNWEISEPIVNNFGD
                     "
     gene            complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="ACG8ZV_000893"
     CDS             complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="ACG8ZV_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HFS4996253.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(38477..39475)
                     /gene="yvcK"
                     /locus_tag="ACG8ZV_000894"
     CDS             complement(38477..39475)
                     /gene="yvcK"
                     /locus_tag="ACG8ZV_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine diphosphate-N-acetylglucosamine-binding
                     protein YvcK"
                     /protein_id="HFS4996254.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAIDR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="ACG8ZV_000895"
     CDS             complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="ACG8ZV_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HFS4996255.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            complement(40491..41222)
                     /locus_tag="ACG8ZV_000896"
     CDS             complement(40491..41222)
                     /locus_tag="ACG8ZV_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HFS4996256.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLQPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTVLQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSKALDTASEK"
     gene            complement(41226..42491)
                     /locus_tag="ACG8ZV_000897"
     CDS             complement(41226..42491)
                     /locus_tag="ACG8ZV_000897"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HFS4996257.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="ACG8ZV_000898"
     CDS             complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="ACG8ZV_000898"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HFS4996258.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQDIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="ACG8ZV_000899"
     CDS             complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="ACG8ZV_000899"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HFS4996259.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQVRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKNAAKALDFETAANVRDMILELKASK"
     gene            47833..49335
                     /locus_tag="ACG8ZV_000900"
     CDS             47833..49335
                     /locus_tag="ACG8ZV_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HFS4996260.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            49337..50074
                     /locus_tag="ACG8ZV_000901"
     CDS             49337..50074
                     /locus_tag="ACG8ZV_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFS4996261.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(50442..51608)
                     /gene="dnaJ"
                     /locus_tag="ACG8ZV_000902"
     CDS             complement(50442..51608)
                     /gene="dnaJ"
                     /locus_tag="ACG8ZV_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HFS4996262.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(51759..53588)
                     /gene="dnaK"
                     /locus_tag="ACG8ZV_000903"
     CDS             complement(51759..53588)
                     /gene="dnaK"
                     /locus_tag="ACG8ZV_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HFS4996263.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            complement(53639..54202)
                     /gene="grpE"
                     /locus_tag="ACG8ZV_000904"
     CDS             complement(53639..54202)
                     /gene="grpE"
                     /locus_tag="ACG8ZV_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HFS4996264.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            complement(54296..55339)
                     /gene="hrcA"
                     /locus_tag="ACG8ZV_000905"
     CDS             complement(54296..55339)
                     /gene="hrcA"
                     /locus_tag="ACG8ZV_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HFS4996265.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEEKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            complement(55574..56740)
                     /gene="hemW"
                     /locus_tag="ACG8ZV_000906"
     CDS             complement(55574..56740)
                     /gene="hemW"
                     /locus_tag="ACG8ZV_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HFS4996266.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMRLMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYRDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            complement(56756..56983)
                     /locus_tag="ACG8ZV_000907"
     CDS             complement(56756..56983)
                     /locus_tag="ACG8ZV_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HFS4996267.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            complement(57303..57626)
                     /gene="relB"
                     /locus_tag="ACG8ZV_000908"
     CDS             complement(57303..57626)
                     /gene="relB"
                     /locus_tag="ACG8ZV_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HFS4996268.1"
                     /translation="MRFFKRGNYRAMITVRVSDAKKEWLSYMAEFYGITLSELLKNYS
                     MEQLEDEYNRQTAEIAHKHWIRSGKTTVFMEESLMNLVGWNDLPFKIHARNSEAALIG
                     KYVYW"
     gene            complement(57969..58415)
                     /locus_tag="ACG8ZV_000909"
     CDS             complement(57969..58415)
                     /locus_tag="ACG8ZV_000909"
                     /inference="COORDINATES: protein motif:HMM:NF013964.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HFS4996269.1"
                     /translation="MKIKIYNQEENQTRHIRNLSNAKLEEEARKVSNYNKKMAAKYVN
                     EEEFCFSKTKIYKRNPFVSEYVKRLAKGICQLCQEKGPFIKDGVPYLHCHHIEYLSQG
                     GKDVIENCIALCPNCHARIHELELPDDKEKLLKIVEKRENSFSKIP"
     gene            complement(58396..58992)
                     /locus_tag="ACG8ZV_000910"
     CDS             complement(58396..58992)
                     /locus_tag="ACG8ZV_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HFS4996270.1"
                     /translation="MNPTLITKKELLKKLDISTGVLANLIRNGMPKEGEMFNLDKIIT
                     WRENWSKNILGELEVGRVYTNKEISEKFKCSKQGGMRRSHQTNTLVLFSDQTGSNVYK
                     DKWLNGILQYTGMGLKGDQVLDKNQNKVLANSKSNFVKIHLFETFKPKEHTYLGEVYL
                     AGQIYTVNEKDSSGNSRKVYKFPLALINQEQLIEDKDI"
     gene            complement(59476..59637)
                     /locus_tag="ACG8ZV_000911"
     CDS             complement(59476..59637)
                     /locus_tag="ACG8ZV_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996271.1"
                     /translation="MTEKEQVQQIVKKYNKSIADLSENASAKEFKTVMNYVADEANRK
                     QRKLVGLDK"
     gene            complement(59630..60304)
                     /locus_tag="ACG8ZV_000912"
                     /pseudo
     CDS             complement(59630..60304)
                     /locus_tag="ACG8ZV_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
     gene            60827..61434
                     /locus_tag="ACG8ZV_000913"
                     /pseudo
     CDS             60827..61434
                     /locus_tag="ACG8ZV_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313657.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase family
                     protein"
BASE COUNT        17077 a        13213 c        10646 g        20598 t
ORIGIN      
        1 taaaaagact aagaaacaat aacaaaagtt aacacttctt agtctttctt tagcacgtct
       61 atttattaaa gattttaggg ccttttctca tgtttttacg atcattctta ggtgtttcca
      121 tttgtttgga tcggcctcca ccttgtttct ttttgatcaa ttctttcatt ttttcttttt
      181 ggtccatttt tattctcctt taacgaatga agcgactaat tcgatatgat gggtttgcgg
      241 gaaaagatct acaggctgaa ctttcttcac ggcataacct gcttctgcaa ataacttagc
      301 atctcttgca aaagttgccg gattacatga gatatagacg attcgttctg gtgacatttc
      361 gattgctgat tcaataaaat gatgatctaa tccttttcgt ggagggtcaa ctacgatcac
      421 agatggtttg atcccttttt cttgccattt tttcataact ttttctgctt ttccgacttc
      481 ataatgaaca ttttcgattt tattatttaa agcattgaac tgtgcatctt caattgcttc
      541 tggaataact tccatcccat acaccttatc cactctgtct gctaaagaca agccaatcgt
      601 acctattcct gaataagcgt cgatcacaat gtctttttta tctaactcgg caaactcgat
      661 ggctgtttgg tacagatact ctgcttgttg agtatttact tgataaaatg actttgctga
      721 gattcgatag gtttttccta atagctgatc ttcgatatag tctctgccat ataaaacttt
      781 ttctttgtct cctaaaatca catttgtttt ttcttcattg atattttgga tgaccgaaac
      841 cacttctggc aattcttcat gaatagcttc agcaatttcc ttggatttaa agaatttttc
      901 tttacgagta actaaaacga ccatcatttc atgggaataa tgaccacgac ggataatgat
      961 gtgacgaagc tgtccttcat ttttttcttc attatatcct cgtacttgga accgttgcaa
     1021 gatatctctg actactttga ttgcttgatc gatgacagga tcttggatat aaaaatcttc
     1081 gatagggact agatcatggc tattcttttt gtaaaaaccg gtggctaact gtccatcgat
     1141 acggcgaaca gggatctgtg ctttattacg gtagccgaat ggttctgcca ttccgaccgt
     1201 tggaagtaca ggaacttctg gcatcttagc aatcttcgcc attacatgct ctacttgttt
     1261 ttgtttgaag acaagctgtt gttcatactt caaatgggct aaaggtgcga tacctatgcg
     1321 aagtaatgca ttgttttcta caggctgacg atcaggtgat tgtgtaataa atgtttcgac
     1381 ttttccatat ccaaacttat tgcctgcttt tactactagt atttctactt cttctccagg
     1441 gagtgcattt tcgataaata atggataacc atcgattttt gctaccccca ttccttcata
     1501 actcaagtcg acgatttcga ctgtatatcg ttcgtttttc tttactattt gctgttctgt
     1561 catattttgc tcctttaagc ctatttttca atcctactga actctactat aaatcagcta
     1621 attacacaac taaaaccggc actgacctta ctacgttcag caccggcttt tgattaattc
     1681 ttttgattag gtgtttcgtc tgctattttt ccgtcaccgt cgatatcttc atccgttaaa
     1741 cgttcgactt cttttacgaa ttctttgctg acaacctcta attcttcttc atctgtacct
     1801 gtgattgctt catcaggaat ctgatcggta ttggcaaaga actcaatgtg ttgatgaaga
     1861 ttttggaaat gcatcggtgc ttccccgccg tattcaccat ctaagttgat cattactggt
     1921 cgattgatat catcttctgt ttcaacgaac aaactgcttg ttttggtata gattattctt
     1981 ggatcatcga catgtcgacc gccattcagc atgagtgctg caatatgcaa gatctcaaag
     2041 atatttgctg tcttcacaat gattaaagaa aacttcccat catccaattt ggcatctggc
     2101 gcgatctgtt cgaatcctcc aacagagttc gtcagcccta ggaaaaacat cgaagcattt
     2161 ccgatatatt ccccttcatc atacttcaag cgcattttga ttggctttac tcgagggagc
     2221 atctctgctc ctttcgcaag ataagcaaga taaccaaaaa tactctttag ttctgatgga
     2281 acttcataag tcaattctgt caaatagcca cctgcagcga tattgatgaa gtaactgtta
     2341 tcagaaaggc cgatgtccat ttttacggtt tggtgttttt ttatcacttc tgctgctgct
     2401 ttaatattat ctctaggaat ttttaatgct cgagcatagt cgttcgttgt accagctggg
     2461 atgatggcca ttttaggacg gtgttcaagc ggagcgattc cattaaccac ttcgttgatt
     2521 gtgccatcgc caccagctgc cactactaga tcaaaaccta gttctgcgac tctacatgct
     2581 tcattcttgg ctgaatctgg ttctggtgta gttgcatagg cgctggcttc aaatcctgct
     2641 tcttctaatg cctgtaggat atccgccaaa ttttttttca ataattcttt tcccgaggtg
     2701 gggttataaa ttacgcgtgc ttttttcatt ttcagcctct atcgtttcgc taattcatct
     2761 ttaagtagct tattcacgac accaggattt gcttgtcctt tagttgcttt catgatttga
     2821 ccgactagga agccaaccgc acgatctttt ccatttttga aatcatcgac agattgttgg
     2881 ttgttatcca aaatttcatt aatgattggc agtagtttgt tcggatcaga taattgcacc
     2941 caaccatttt tttcaactac ttcttgggct tctccgccat ttgtgatcaa ttcacggaag
     3001 acttttttgg cgatttttga gctgatcgtt ccatcggcga tcaaacgaat cattcctgct
     3061 aagttctcag gtgtcaattt tgtctcagct aattccagtt tctcactgtt caagtaagca
     3121 gaaacttcac ccatcaacca gttagatgct tgcttggcat ctgcaccatt ttccaaaaca
     3181 gcttcaaaaa aatcagacat ttcttttgta agtgtcaata ccattgcgtc atactctgga
     3241 agtccaaact cacggatata gcgttcgcga cgagaagctg gcatctcagg caaactagct
     3301 tttacttttt gaatccattc gtcatcgatc acgaatttcg ggatatcagg ctctgggaag
     3361 taacgataat cactagaccc ttctttgaca cgcatcaaaa ctgttttatt cgttgtttcg
     3421 tcaaaacggc gtgtttcttg ttggatttct cctcctgaaa gaagaacttt tgcttgacgt
     3481 ttttcttcaa aagctaaacc ttttttcacg aaagataaag agttcaagtt tttcaattct
     3541 gctttcgtac cgaactcttc ttgtccataa gggcgaagag aaatattggc atcacagcgc
     3601 atagagcctt cttccatttt cacatcgctg acttctgtaa attggataat tgatcgcaat
     3661 gcttctagat aagcgtatgc ttcttctggt gaacgcatat cagcttcaga aacgatttcg
     3721 atcaaaggcg tgccttgtcg gttcaaatca acgtaagaat aaccgccaat accatgcatg
     3781 ttttttccag catcttcttc taaatggaca cgttcgatcc ggattttttt ctttttacct
     3841 tctacttcga tttcgatcca tccgtcatga ccgattggtt gatcaaattg ggaaatttga
     3901 tatgcttttg gattatctgg gtaaaagtaa tttttccggt caaaatgagt atctttagag
     3961 atttcacagt ttaatgccaa agctgctttc atcccgaatt ccagcgcagc tttattcatt
     4021 actggcagca cgcctggata accccagtcg atcacgtttg tattgctgtt tggttctgca
     4081 ccaaaatgag ctggcgctgg agagaaaatt tttgagttgg tttttaactc gacgtggact
     4141 tctagtccaa tgactgtttc aaaattcatt cgtctttccc tcctaaaata gctggttgtt
     4201 gtttatggaa ttctgttgct tgttcaaacg catatgccgc ttgatacatc gttttttcat
     4261 caaaataatt accgatgatc tgcaatccaa ctggtaatcc ttctgataaa cctgccggta
     4321 cagacatacc tggaagtcca gccaagttga cagggatcgt taagatgtca ctcatgtaca
     4381 ttgtgattgg atcgttaatg ttctcaccga ttccgaatgc aactgttggt gaagatggcc
     4441 cgatgatcaa gtcataatct gcaaagactt tttcaaaatc tcgtttgatc aatgtacgga
     4501 cttgtcccgc ttttttgaag taagcgtcat aataaccagc acttaaggag aatgtaccta
     4561 acatgatacg gcgttttact tcttcaccga atccttctga acgtgagttg acatatacat
     4621 catctaatga tttcacattt tctgagcgat aaccgtagcg gataccatcg aatcgttgca
     4681 agttggaact tgcttctgat gaggcaatga tataataaac agccacaccg tattttgaat
     4741 gaggcaagct gacttcttcc acaacagcac ctaatgaacg gaatgtttct gctgctttca
     4801 atacagcttc ttttacgcca ggggccacac cttcgcctaa gtattcttta ggtaaagcaa
     4861 tcttcattcc tttgatgtcg cctgtcagtc cctctgcaaa atcaggaact gaaacgcctg
     4921 aagaagtacc gtctttttcg tcataaccgc tgatagctgt caatgctaat gcattatctt
     4981 tcaccgtacg ggtcattggt ccgatttggt caagagatga agcaaaggca atcaaaccaa
     5041 aacgtgagac acggccataa gtaggtttca tccctacgat gccgttaaaa gctgctggtt
     5101 ggcggatact tcccccagta tcactaccta aagaaactgg aatttgtcca gctgcaactg
     5161 ctgctgcaga accaccagaa gagccaccag gtacttttgt tgggtcccaa gcattttttg
     5221 ttttcttgaa ataagaagtt tctgtacttc cacccatagc aaattcatcc atgtttagct
     5281 taccaacagg gatcatatct gcttgataga ttttatccat gaccgttgca tcataaattg
     5341 gttcaaaatt gtaaaggatc ttagatgcag cggttgtcaa gatatctttt gttacgatat
     5401 tatccttgat accaattgga ataccagcaa ggacgttgct ttcatcaatc cctttttcat
     5461 ctaaagcttt tgcctgttcc aatgcttttt cttcgttcaa tgtaatgaat gcttcgacct
     5521 caggctctgt ttctttgatt cgttcaaatg ttgcttttgt caaatcttgt acagtgattt
     5581 ctttcgatac aagcatatga tgcagttctt ctagagaacg attgtgtaat tctgtcatta
     5641 tgcgccagcc tccccattat cgatgattgc gggtactttg ataaagccgt cttctgtttc
     5701 cggcacattt ttcaataatt catcgcggtt ccatccagct tgcgcccgat cttgtcgcat
     5761 cacgtttact gtttcaacca cattcgacgt aaatggaaca ccttctgtat ctacttcttc
     5821 cagcatttca accatatcga tgattttacc taattggtcg gtaaaacttg caagttcttc
     5881 atctgcgaac gcaagttttg ctaatttggc aacgtgtttc acttgttctt cactaatcgc
     5941 catactaccc cttctttcta aacgagttaa aaactttgct ctctatttta acacaagagt
     6001 gccgtgtctg aaattgttta ttgaaatttg tctgaaaaaa ctcatttttc attcttctac
     6061 tgagcgactt ttagccaatg catctgccat ttgatcttct gtccaaactt cgattcctaa
     6121 ttcttgtgct ttggtcagct tgctgccagc atcttctcct gctaccacga tatccgtttt
     6181 tttcgatacg ctaccagtca ctttcccgcc aagattttcg atcgtctctt ttgcttcttc
     6241 acgagtaaat cgtgttagtt taccagtaag gactactgtt ttttctttaa aaggagactc
     6301 gacttcttgc aattgggcat ttcgaagccc tttgtattcg aaattgacgc ctgcttgttt
     6361 taattcattc atcaattcat ggacttcttc gttactgaaa taagtgacta cactgtcggc
     6421 aatgatatca ccgatcgtat caagcgcaat aatcgactca tagtcacttt tactcaatgt
     6481 ttctagatca ccgaaatgtt ctgctaaaat ttttgctgct ttcgctccga catgtcggat
     6541 tcctaacccg aaaatcaacc gctcgaccga attatctttg ctgttgtcga ttgctgtcaa
     6601 aatattattt gctgattttt cttttatttt gtccaacgtc aataactctt cttctgtcaa
     6661 tttgtaaaga tcagcaacat ctgctactag ttttttatca tacatctgtt ctagtacgcg
     6721 cggccccaac ccatcgatat tcatcgcatt tcttgaaaca aagtggttca aaccttcttt
     6781 catttgagca gggcatttag gattgatgca ccgtaaggct acttcttcat ccaaatggac
     6841 aagttcactt ccacaaactg gacaatgtgt aggcaattgg tattcttcgc tgtctttagg
     6901 tcgtttatct aacacgactt gcgaaacttc tgggatgatg tctcccgctt tataaatcag
     6961 aactgtatct ttcaagcgga tatccttcaa cttaatataa tcaccgttat gcaggctggc
     7021 acggcttact gtcgttcctg ctactcggac tggtgtcatg atagctgttg gcgttactac
     7081 ccctgttcga ccgactgtcc attcgatgtt ttcgattagc gtttcaactt cttctggcgg
     7141 aaacttgtaa gctgctgccc atctcggtgc tttgacagta aaaccaagtt gatcttgtag
     7201 cgagaattca ttcactttga tgacgattcc atcgatttca tagggcaaat ccacacgttt
     7261 gtcatgatat tcttcaatgt atgaccacac ttcatcaatc gaatgacata gacgtttttc
     7321 ccgattcgtg tggaatccaa ttttttctag ctcttctagc gcatcatact gggtttttgc
     7381 ttgcatagga ccgaaatcag ctactgtgta taaaaaagtg tccagatttc ttttcgctgt
     7441 gattttagaa tctaactgac gcaaagaacc agctgcggcg ttccgaggat tcgcaaagat
     7501 atcttttccc tctgcttctc tgtcttggtt caattggaca aatgaccgtt ttggcatgaa
     7561 acattcgcct cttacttcga tgttcattgg ttcttttaat ttgattggga ccgaccggac
     7621 agtttttagg ttttcagtga tgttttctcc tacagttcca tccccgcgag tcgcacctct
     7681 cacgaaattt ccatcttcat aacgcaaaga aacggaaagt ccatctattt ttagttcaca
     7741 gcaatagtca actacacgtc ccactgcttt ttgtacacgt tgatcaaaag ctatcagctc
     7801 ttctttgctg aaaacgtcgt tcaaactgta aagcggaata tcatgagtga ctttttcaaa
     7861 accttctaat acttttccgc ctactcgttg agtgggagaa tcagacgtga tcaaatcagg
     7921 atattgttcc tcaattgcta ctaattctgc gtattcttta tcataaacat agtcttccac
     7981 tgttggttta tcttctacgt agtattcgcg agaccattgg ttcagtcttg tacgaagttc
     8041 ttctgctcgt ttagcagctt cgtcaatcgt catttcatgt tccatcattt accctccact
     8101 actaagcttt ttcaattggc gcaaaggcag ccaaaagacg ttttactcct tgacttggga
     8161 aagccacatc tagttctaga tccttcgacg tcccgcttac tcggacgact gttcctagac
     8221 cccatttttt gtgtttgact ttatctccag gtttccagct gttattttcc cctccagtag
     8281 cacttttaga gggaacaacc gctgtctctg gctgtttata gctatatgct gtttttttag
     8341 cgaatacagg tgttttttta ggcgtaggac gcatgccttc gatttccagt aactcctgat
     8401 cgatttcttc tacaaaacga gaaggtcggt tatattgcgt ccgtccatat aatgttctgg
     8461 agaaagcatt tgttaaatac aacgcttctt ctgctcgcgt gatccccaca tatgcgagac
     8521 ggcgttcttc ttccagttcg ctttcttcca tcaatgctcg agataaagga aaaaccccct
     8581 cttctagacc aatcaggaat acaactggga attctaatcc tttggctgca tgcaaagtca
     8641 tcaatgtcac ttgggaagca tcttcttcta aattgtcaat atcggaaaca agtgccagat
     8701 catttaagaa gaccgttagt ttttcttctg gtgcatcagc gtcttcttca ttttgctgtt
     8761 cgaattgttt gtcgaattct tgtgtgaccg ttaaaaattc ctccaagttt tcgatgcgtg
     8821 cttgtgcttc taatgtattt tggattttta agtcttctag atatccgcta cgatccaaaa
     8881 cctctttcgt caattctgtc actgtcaagt atgggatcat ctgagtgact tcttggatca
     8941 tctctccaaa tgcacctaat tgctgtcctg cttttccacc gatatttgcc agatccacat
     9001 tttgcgctgc ttcaagcagt ggccattcat gaagagaagc aaaactgcgt agtttttcga
     9061 tagatcctgg tccgatgcct cgtttgggcg aattaacgat acgctcaaaa ctgattgaat
     9121 cttgaggatt tgccagcaca ttcaaatacg ctaaaatatc tttgatttct ttacgatcgt
     9181 agaacttgtg ccctccaacc attttataag gaatatttgc tttcaacaga gtttcttcca
     9241 ttacacgaga ttgtgcgttc gtccggtaca agatggcaaa gtcgccgtaa ttccgatgat
     9301 tgcttcgaat ctcttcttgc atccgatcta cgataaaacg ggtttcgtct cgttcattat
     9361 ctgcacggta gtaagtgatc ttgtttcctt ctttgttttc tgtccacaag ttttttggtt
     9421 ttcgattgct attgttttca atgacttggt ttgctgcgct aaggatgttt ttcgtggagc
     9481 gatagttttg ttctagcaaa attactgcag catctggata atctttttca aaatccaaga
     9541 tgttctgcat atctgcaccg cgccagccgt aaatactttg atctgcatct cccacgacgc
     9601 acaggttcct aaatctacct gccaataaat tgactagcgt atactgtgcg tgatttgtat
     9661 cttggtactc atctacatga atataatgga atttgttttg ataatatgtg agtgaatcag
     9721 gatgttcttc aaataatcga atcgtattca tgatcaggtc gtcaaagtcc atacattgat
     9781 tatattgaag ctctttttgg taagcagcat aacattttgc cgcaatctct tcgtaataac
     9841 tgccttgcat ttttgcaaaa tcctgagggg tctgcaggct gttttttgct tgagagattg
     9901 ttcctaatat acttcgagga tcatattttt tcggatcaat gttcagttct tttagtatcc
     9961 gtttcatcaa ggtcagctgt tcagaagaat cgatgattgt aaagttccgg ttatacccga
    10021 taaaatcaac atctcttctt aaaatacgca cacacatcga gtgaaaagtc gatacccaga
    10081 catcttcgcc tccagatgcg agaatcgcat tgacacgttc tttcatttct tttgcagcct
    10141 tattggtaaa agtaatcgct aggatgttcc aaggattgac ttctttttcc tcaatcaaat
    10201 aggcaatgcg gtgtgtcagc actctcgtct ttccacttcc tgcacctgcc attagcagta
    10261 atggtccgtc agtgtgaaga acagcttctt tctgacgggg gttcatcccg tttaataatt
    10321 cagctttgga tgacattaac aacatccttt cttttatcaa tcttgttaat tatagcattt
    10381 tcttggcttt cattaaacta gctagttcaa aatcatttgt ttctttttat ggatttttcc
    10441 ttgtcaattc gttgatttcg cgctaaatta aaagaaagcg aggcgtttga atggaaaaaa
    10501 aaggaaaaat caagaaatta gataagactc agatatattt tattctaaaa ggaatatttg
    10561 ttggactgct gacaggaatc gtcgttagcc tgtttcgatt atctatcgaa aagctaagcg
    10621 atttagttcg aagtatctat gaaatgagtc gggaacagcc gatttactta attggcctag
    10681 ctatttgctg catccttgca gcatttttcg tgggttatct ggtcaaaaat gaaccggata
    10741 tcaagggaag cgggattcca caagtagagg gacagcttcg cggggaatta tcaatgaact
    10801 ggttctctgt tttatggaaa aagttcattg gcggtgtact ttcagttggt gcgggccttt
    10861 ttctaggtag agaaggacct tctatacagc ttggcgcatc cattggacaa ggagctggac
    10921 aattgtttcg gagtccatct tcagaagaaa agattttaat ttctagcggt gcaagtagcg
    10981 gacttgcagc agcattcaat gctcctatcg caggattact ctttgtttta gaagaaatcc
    11041 atcactcctt ttctccactt gtttggctga catcatttgc ttcagcaatc actgctaact
    11101 tcgtctctct ttactttttc ggcttgagac ctgttttata tctaggtgac cttccttctt
    11161 tgccgttgaa atattatggt tccttagtga tcttaggagt acttctaggc atcttaggtt
    11221 ttatttatca gaaggtcttg ctggctttgc caaaatttta caaccgattg cctttaccag
    11281 cttattttca cgggttcgtt cctttcttgc tgattttgcc aattggttat ttatggccta
    11341 gtactctagg cggaggcaat caaatcgttt tagcttttgg acatgcttcc ttgccaatca
    11401 ttatgattat cggtttgttt gttcttcgat tcgttttttc catgatttct tacggtggtg
    11461 gtcttccagg ggggattttc cttccgatat tgacattggg ggctttaatc ggtagctttt
    11521 atggaaacat tatggttgat ttcgggatgg atccaatcta catcaaggat tttgtcgtta
    11581 ttgccatggc tggttatttc acagcgattg gaaaagcacc gctgacagca attattttag
    11641 tgacagaaat ggttggctct cttaatcatc tgatgccttt aggattggct gctcttgttg
    11701 cttatatcgt caatgacctt ctcggcggta atccaattta cgaatcatta ttggaacgtc
    11761 tacttggaaa tactcagacc gcctcactaa aaggtgcaag gacaactttt gattttccag
    11821 taacggcaga gagttcttta gacggattaa tggtacgaga cttcaattgg cctaaaaata
    11881 tgctgctaat ctctatacgc agaggaaatc aggaaatctt gactcacggt gatacgatca
    11941 tgaatgtagg agatattttg gttatcttga ctgatgaagc aaacttgcca agaatcaagc
    12001 aggaaatcga ggctaaatct tctatcacaa atttgaagca atcattttaa cgaacatgga
    12061 aaaactattt tacaacaact attcatctac actacttgat tctatatgat tctataaaaa
    12121 aagaagagac tgggaaaaac cagcctcttc ttttttattt ctatgcttct gctgctgcag
    12181 gagcttttct caataaacca taaatcacac cagatacgac tgctccgata gcaataaaca
    12241 ccaaatacat gaccgggtga ctcagtaaga atacaacgaa aatcccgcca tgaggagcca
    12301 gtaatttgat cccgaaagct ccgactaatc cgccagttaa agcagaacca ataataaaac
    12361 ttggaatggc acgaatcggg tcagctgctg caaatggaat cgatccttcc gtgacaaacg
    12421 atagtcccat cacgatgttc gtcaaaccag catcttgatc tgttttgctg aatttattct
    12481 taaacaaacg tgtagcaacg aaaattgcca atggaggtac cattcctcca gccataacag
    12541 aagccatcac gacacttccg ccagttgcaa cagtcgtagc taaagttgct gtaccaaaca
    12601 cataagcggc tttgttgatt ggaccgccta aatctgccgc catcattcca gctaataatg
    12661 caccaagtaa agcagcattc gaaccactca tacttgtcaa gaaaccgttc aatgcatcat
    12721 tgattgcttt catagggaca ttgaccagca acatcaagaa accagtaatc agtaagccaa
    12781 acactggata aaagaggatc gttttaattc catccaatga ttttggtaag ttcttgaata
    12841 atttacgtaa aaatacgatg acataaccag ctaagaatcc accaatcagt gcacctaaga
    12901 atcctgcacc gcctgtatta gctaatgcac cagcagcaaa tccaacgatc aaaccagggc
    12961 ggtcaccgat acttgaagca ataaatcctg ctaataccgg cagcatgaaa ccaaatgcag
    13021 cttgtccgat ttggttgaac cagctagcag cttgattgta attccctaga tttgataatt
    13081 gatcatgtgg cacgccaata aattggtcga tcatgaaaga aagcgcaata gcgattcctc
    13141 caccaataac gaaaggtaac atgtgtgata cgccgttcat caaatctttg taaattcttt
    13201 gtccgatagt accatccgca tttccttctt ctgaactgct ttcttttcca tcaccatgga
    13261 atactggtgc agtaccacta agggctagat tgatcagctc ttctggttta cggataccat
    13321 cactgacagg acgattgatc agttcttttc cgtcaaagcg attcatctct acttttttgt
    13381 ctgctgcaac gattacacct tctgcacggg cgatgtcttc agcagtcaat cggtttttga
    13441 ttccttctga accgttcgtt tcgactttga tctccacacc catttctttc gcttttttct
    13501 tcagagcatc ttctgccatg taagtgtgag cgatccctgt tggacaagct gtaacggcaa
    13561 caacgaattt tctttctgga tgagcagaag cttctgcagc ttgtgtttct tgttctgctt
    13621 tttcttctgc ttctttttgc tcttcagctg tttggaacaa gtcttggact tcttctggtg
    13681 tatttgcttc ttttaatttt cctacgaaat ctgcatcaat cagcaatcga gatagtgctg
    13741 ctaatgcttg caaatgtgtg tcgtttgcgc cttctggagc tgcgatcatg aaaaacagat
    13801 aagttggctg tccgtctaag gcttcataat ctactccttt ttggcttttt gcgaataaaa
    13861 ctgttgcttc tttaactgca ctgtttttcg cgtgaggcat ggcgattcca tcaccaagac
    13921 ctgtagaagt ttgtgcttcg cgggctagaa ttccttcttt atatgtttcg atatcggaaa
    13981 tccggccggc atcaaacatt ttttggacca tttcatcgat tgcgcctttt ttatcagtcg
    14041 cttgcaaatc catgatcatc gcttctttga ccattaaatc cttgatattc atgattatcc
    14101 tccttgaaac taatcaattt ttgtgatttc aacttctggc agcaactcat caatcaattc
    14161 gcgagctgcc aagtcatcag aaaaagctgt tgcgcttccg caagcaactc cccatttaaa
    14221 ggcttcgatt ggatctttcg tacggctgta agccccaata aagccggcaa tcattgaatc
    14281 ccctgcacct actgaatttt tcaatgggcg aactaataca ttcgttttat aagttccttg
    14341 ttccgtgaag agcaaagcac cgtctccagc cattgagatc agcacattct gtgccccttc
    14401 agctagcaat tttttaccat acggaatgat ttcttctaca gattggaagg ttgtattgta
    14461 aagctcagct aattcgtgat tgtttggttt gatcaacaat ggtttcttaa caagtgcatt
    14521 ttttaggtca tcacctgttg tatcaatcac gaaatctgca cctttttctc gaatgatatc
    14581 aatcagttct tgataaaatc cttttcgcag gctagccggc gcgcttcctg acaatacgac
    14641 gatatctcct tgtcctactg ttcctaatgc ttgcttcaac tcatcgattt cttcatctga
    14701 aatagatggg cccaaaccgt taatttcagt ttcagtatct gattttagtt tgatattgat
    14761 tcttgtatct tcttttacgg ttgtgaacaa agactggatt tgttcttttt caagccactt
    14821 cgaaataaat tcgccagtga accctcctaa aaaccctagt gctgtagatt gagaatcgat
    14881 ccgtttcaaa atacgggaaa cattgatccc ttttcctcca ggtaacttga agtcttcctt
    14941 cattcggttc aaatcgccta gttttaaccc atctacgcgt acgatataat caattgatgg
    15001 attaagtgtt actgtgtaaa tcattgtatt gcctccttaa ttgttgtctt ttcacggaat
    15061 tcattaacga attctaatgg acaacgctcg gttatgatcg tggctgcttc caaaggtgca
    15121 acagaggtga aggacaactg gttgaatttg gtatgatcaa tcaatacaaa tgtctcttcg
    15181 gaatttttca tggctaaacg tttaacagct gcctcttctg ggtccggagt cgtgaatcct
    15241 tgttcaagat gggcaccgtt cattcccata aatgctttat taaaatgaaa attttttagt
    15301 tgttctatcg cattagatcc taaaacagca ttagttgcca gctttatcgt tccacctaaa
    15361 ataatggtag caagctccaa atcaactaaa tttgccgcat gttgaacgga atttgtcact
    15421 actgtgatct gttttccttg cagaaaagga atcatttcta acgtagtaga gccagcgtct
    15481 aaataaatga catcttcgtc attaatggtt tcagctgccg atttggcgat ttgctgtttt
    15541 tcgtgaacgt ttttgagtga tttttcactc atattctgct caaaattcaa taattgctct
    15601 ttcttagctc cgccatgaac tctttctaga aacccactat tctccagctc ttgtaaatca
    15661 cgtcttatcg ttgattcaga agcattaaaa aggtttacaa gatcttgtga tttcacgatt
    15721 ttctgctgtt caagcaagtc taggattttt tgtctacgtt cctctgtaag cattttcacg
    15781 atcacctcaa tacaaataat agcatatttt ttttctactc gcaatataaa tcagtcaaaa
    15841 acgttcataa aaattataaa tcagtcaaaa aaaaataaaa aaccagtcaa aaagactggt
    15901 tttttatttt tttgtctatc atcaagccgt tttatcgttt tttattttcg cttcttgttt
    15961 ttttcatata aacagaagca ggttttcttt ccttatgaag aagataataa taaagtccca
    16021 tcccgccaaa catgaccaaa aaaccgatga ctgatcgaat aggaaaatta ggaacaaaaa
    16081 agagacagac ggataataat gatgccggaa ccattattcg ataatagagt tgtttatcca
    16141 ttttcttcac ctcatatttt ttgtaaagta atcaattgtt ctaattctcg gtaatctaaa
    16201 aattgcacac gcagatgctg ctcacctttc ttgacatcga attggatact tcgccgcttt
    16261 ttctttattc gtttgaaggt aacatcagag agtctatgtt tgatttcctt taacggtaat
    16321 tctgacaggg attctgaagg aacatagatt cttaaggata aaagatactc ttgatatttt
    16381 tcatctgtta cctctacttc tagatattcc ctaatataat aacaataagc ttcgattcca
    16441 ttatccaaag caacagtcgg atcgataact ttatagcaca tcatgcgcga gcgattctcg
    16501 tcaacccaag gaaaatacgc ctgagcattt agtgttccgc gaacacgcct ttctttataa
    16561 tctccttgtt gaatatcata actttttgtt acaaaaaatg aagcattctt tttaggaaca
    16621 ggttgcattt gtgcattctg atactggaca gattggatcg tatggtcagt gtaaatgtat
    16681 tcaacgaatg gcggtttcaa taaaccgaca ccattgtccc aagcaagatg atcaaaccca
    16741 agctggtccc taaaatagga ttgaaacatt tgattgtttg gcttttgcca gttaaagggg
    16801 tctcgataaa gctggataca tatgacttcg ttttctaatt ccttcacttt ttctacttgt
    16861 tggatgtcga gaaaaatcgg tttagggatg atttgatgat aatagcgact ataatacatt
    16921 tcccaacacg aagtgaaaca taaaccttgg taaaaaagat cgtatcctgg aaattggttg
    16981 caatcgacta ctacttcccc gttttgttgt ttcattttag gtaaatgttc gatttcatcc
    17041 tttttctcaa acaatagccg ttgagagatc tgttttgtat tgtgatagat aaactcgcta
    17101 taagctcgca tataggcgaa caccccatga gcaatcattt ttttctgaat gaagtctcga
    17161 atcaaaaatt gcttttcttt gaaaacagag atagacaata cattttttat caataattga
    17221 ttatcttcca agcgaaaact acattcgttc tcgtcatttc ctacaactaa ccaactttcg
    17281 tctcttaccg atgctagcat tattttttct tgaagctttc gaagatcata cggatccgct
    17341 tgttgtgtga aagagcggat aaatgttggc tggatcaaca gacgtgtcaa aatagcccaa
    17401 tcgcttattt cctgtttttt ttcttcttca tttaagtctg tgagctggat agtcatcaat
    17461 aatttatctt cgccaatcat tttctcacct ctttaaaatc tttttataat ttaattataa
    17521 ccaacgataa agaaaaacta aaactttatg tcttagaaac caatttggac gattacatga
    17581 tagactaagt aaaaagaaac aaagaggtgt ttacaatggg gttgaaattt gaacgtacag
    17641 ataatttaga taaacttttc gaatcatttg ctgtcgatcc ggaaaaaaca gttgcaccaa
    17701 aagaagagat cgatcgattt ctaaaaccac agccacaaaa tgaaaagaaa aaagacaaga
    17761 aacaaaagta agttaagctc aaaaaaagac ttaccagcca aacttttatg aaagagtttg
    17821 actggtaagt cttttttatt ctttttatga ttcaattgct tgttcgattg ctgcccacgc
    17881 ttcttctttt ccctgttttg taacggaaga aaagagaata aacgtgtcat tgcgatcaaa
    17941 atccaacgct tttttgattt cgctctcatg cttgttccat ttaccacgag ggatcttatc
    18001 tgccttagtg gcaacaacaa ttacagggat atcataatac ttcaaaaatt gatacatctg
    18061 gatatcttct tgagaaggct tatgacgcaa atctactaaa gaaacgaccg cacgtagctg
    18121 gtctctagtc gttaaatatg tctcgatcat ctttccccat tttgctcgct cagttttgga
    18181 tacttttgca tacccatatc ccggaacatc gacaaaatgt aatgcgttct cgatcaaata
    18241 aaaattcaat gtctgggtct ttcctggctt accggaagta cgggctaaat tctttcgatc
    18301 aatcaatgtg ttgataaaag aagatttccc tacatttgat cgtcctgcca gagctatttc
    18361 tggcaattgt gtatctggat attgttttgg tgccactgca cttatgataa tttcagcttg
    18421 atggactttc atggtctctc tccttaacaa ggtgatgaat aaagcaagcg gctgtcgcaa
    18481 aagccaaaat gacttttacg gcagcctctt ttcatcaacc cgcttttttc tctgaatctt
    18541 tatagattac tgttggctca ccagacaatt cagctgcttc ttttgtgata atcacttttt
    18601 cgatgttttc atttgaaggg atatcaaaca tcacatccat catgatttct tcaatgatgg
    18661 aacgaagtcc tcgagcaccg gtattgcgtt cgattgcttt tttcgcaatg gctctcaacg
    18721 cttcaggttc gaattcaagt tcggtattat ctagagaaag aagtttttga tattgtttga
    18781 ctagcgcatt tttcggctca gtcaagatcc gtaccagatc atctgttgtc aatttctcta
    18841 aagctgccat aacaggtaat cgtccgataa actcagggat caatccgaat tttagtaaat
    18901 cttcaggaat gatatgctgc atgacacttt cgtcttcaga aagtttttgg ttttgtgtac
    18961 caaatccaat cgtcttttcg cccatacgat tcttcacaat cgtttcgatg ccatcaaatg
    19021 caccacctac gatgaacaat atgttcgtcg tatcaatctg aataaattct tgatgtggat
    19081 gtttacgtcc tccctgaggt ggcacgcttg caacagttcc ttctagaatt ttcagcaagg
    19141 cttgttggac accttcgccg gaaacgtcac gagtaataga tacattttcg cttttacgcg
    19201 caattttatc gatctcatca atatagatga tccctttttc tgcacgttcc acattgtaat
    19261 cagcagattg aagcaattta agcaaaatgt tttctacatc ttcccccaca taaccagctt
    19321 ctgtcaaact tgtcgcatct gcgattgcaa aaggtacatt caatgttttt gctaatgttt
    19381 gtgctaaaaa tgttttacca gaccctgtag gtccgatcaa gcagatattg cttttttgca
    19441 gttcaacatc atctgtgttt tcttgtgctt gctgattgac acgtttatag tgattgtata
    19501 cggcaacagc taacgagcgt tttgcgcgat cttgtccaat cacgtagtta ttcaatactt
    19561 caagaatttc tagtggttta gggacttcag tgaattcgcg tacagcttct tcataaaatt
    19621 cttcatcaat gatttcttta cataggtcga tacattcatt acagatgtag acccctggac
    19681 cagctacgat ctttttcact tcttcttggg ttttcccgca aaaagaacag cgtacggtct
    19741 cattgctact tggattgtca tacatggtct tcacccctta acttgcaaaa agtatgcaag
    19801 aaactatcaa agactttaca gtcttttact atcataacat agtttagtaa aaagaaaaag
    19861 tgtttaacaa aggatcaact gacctatacc tttgcatttt ttactcttaa caaaaaataa
    19921 ggaactgtga caaaatcgtg tcacagtccc ttatttcgaa taaacaattt tctagaagta
    19981 gcttcttcag aaatgattta ttacttgatt tctattcttt cgcttctgtc gctgtacctg
    20041 tgatcaattc gattgctttt ttcattgtca catcatgttc cagcatatct tctgtcaaca
    20101 cgcgtttgat ttgttcgatt ggcatgttgt atgtttctga taattcttgg atttctgcat
    20161 tgatttcttc ttctgttgct tgaagatttt cagcagctgc aattgcttcg atcacaagat
    20221 ttgttcttgt gcgcatttct gcttcacctt cgaattgttt atgcaagtct tcttctgtag
    20281 aaccagttaa ttgatagtac atttcaggag agataccttg acgttgcatg ttgttcaaga
    20341 attcgtccat tgaacgatgt acttcatcat gaaccatcac gtgtggcaat tcaacgattt
    20401 ctgcgttttc aacagccata cggatcgctg cttcatcttt tgcatcgtcc gctgcttttt
    20461 cttttgtttc tactaattct ttgcgatatt tttctttcaa ttcgtctaat gttgatactt
    20521 cgtcatcaac atcttttgcg aattcgtcat ctaattcagg cacttctttt gcttttactt
    20581 catggattgt cactttgaag actgcttctt ttccagcaag atcttctgct tgataatctt
    20641 ctgggaaagt tacatttaca tctagacttt cacctgattt atgaccaact aattgatctt
    20701 caaaacctgg aatgaatgag cctgaaccta attcaagtga gtaattttcg ccttttccgc
    20761 catcaaacgc ttcgccatct acaaagcctt cgaagtcgat tactactgta tcgccatttt
    20821 cagctgcagc atcttctttg ataactaatt cagcttgtgc ttcttgttca cgtttgatac
    20881 gtgcatccac gtcagcatct gttacttcac ggtcttgttt ttcaacaact agatctttat
    20941 attgtcctaa ttttacttct ggtttcactg ttacttcagc agtgattacc cagtcttgac
    21001 ctttttccat gctttcaaca tcgatttttg gttgagaaac aggatcgatg ccagcttctt
    21061 tgacagcagc ttcataagct tctggtaata cagcattcaa tgcatcttca tataaagctt
    21121 cttcaccgta catacggttg aatacttgac gagaaacttt ccctttacgg aatccaggta
    21181 cgttcaagct ttttttcact ttattaaacg cagttgttaa tcctttttgg atttcgtctt
    21241 gcgcaatcgt aaattttaaa acaccatcat tcgtgccttt tttttcaaat gttgcagtca
    21301 tttaattccc tccgagttta gaaattcatt ttatacatca aaaacgtttc atgcatacct
    21361 ttaaatagta cactaaccct ttcaaattgt aaacatattg aatggataga atccttgttt
    21421 ttcataacat ttttatcttt ttcactgata aaatctaatg gaagaagatc atttgctgca
    21481 aaattttttc tctttttttt aaaaaatctt gtttttcatc ttctgtacct tcatacatcg
    21541 tttttcctgt acacgcctct acagtcagtt gaaaccagcg cttcgggtct tcgatgtatg
    21601 tatcatagac aggataaaca attgcagatt gcaacgtgaa ttcttcattt aacacggaac
    21661 taagcagcgc atcttcatta ccgtaacgat ctgaaaatac acataattgc tggtaacttg
    21721 cctgctgctg cggctttggc agatcttttg gtatgacttt gactaacttt tcttcaatcg
    21781 tcaaatagaa aacaggatgg cattcgttca attgcctaag tgtctccagt aattttgccc
    21841 ttgctaaaat atggacctct ggcgatacaa taagtttact cgctgtttgg ataaactcat
    21901 gataaggaag ctgttcgatc tcatcaatag acgcaagctg acgtgcaggt tccaacgaag
    21961 gaagttcctc cgatttattg tggagtgcct tgatcttctg cctctccatt tgtccggata
    22021 attcttctgc aaattggatt ttttcaatga cccgctgctc gaaagcttca taaaaatctg
    22081 tacttgctat caattttcta gcatataaaa aatcttgtgt actgattaac aagtcaaaat
    22141 aaaattcagc aaactcctca ttttgaagat actgtttttc atgcaagagt gcttgcttca
    22201 atgcttcttt tttctcgtcc aactcgtaaa gacaaaaaac aagcaggcta ttagcctcaa
    22261 agctttcttt caactcgtaa gctcgttgaa ataattcttt tgcctgctga tattgctggt
    22321 ttgctagtgc ttgttgtgct actcgcatta aattctcata tttttctgga aaatcaatcg
    22381 gcttcacgca gtgtcctcct cttgctcatg ttcagctcat gttcaatagt agcaaaacaa
    22441 aaaaagcatg acaattaaaa ataactgaag caccctctaa aagctagatt ttagatctga
    22501 cttttagaag gtgctttcaa ctgttactgc tttttattgc tcatcagctg ttgacttcct
    22561 ggttgaatgc tttgatcaga ttgatcgtaa caacacttgt attagtgaaa aaatcgccta
    22621 gatgttgctt tttctgatta aagattgctg gaagataccc taacatcagc aaaggaaatt
    22681 ttagaatgaa ccggcaagca ccttctctaa ctaaaacggt tgaccagcta agttcttctt
    22741 catcaaagct gatgactcga ataccaaaga tcattttccc aatcgtttga ccatgattga
    22801 atttcgtcaa taaaataaaa tacgctagat aaataagtaa ggctgtgaat ccgtagatac
    22861 tcagataaga atctgaaaaa ttaagccaac ctagattttt ggcaatacca agtgttaaac
    22921 gcgtaatagc tccgatacac aaaagatcga ccaagaaagc aaacattcgg ataaaaaaac
    22981 ctgcatagaa atacttagga aaatcatttg cttttggcgg ttcatttctt gtgtccgtat
    23041 actttttcca tttacgttgt ttctttttga tttcttcggg cgtcaaaggc tctctttcaa
    23101 aagagctcag taccttttgg gaaaagttgg agtcaggtcc tacagcaggc tgctgttgct
    23161 tatctttttc ttgttcctta ttttcatttg aaagctctga catgcttact cacctccgta
    23221 ataatacatt gcttttggtg attccgctgt ccctagattc tcaagaacgg ataagatctg
    23281 actagtctca gaaggcttca atccctggaa ttctgctagt ttacttccta accatgtact
    23341 agcaaaccca gatggcgtgg aagaatattc tactagttcc gcatcttcaa gctgttgttc
    23401 ctttcgcata gcttttaaag catcttcagg aaatcccaat tcatcgacta aacctacttc
    23461 ttttgcttgg acaccatcat aaatccttcc atcagcaatt tttttgactt cttcttcaga
    23521 tttattccgt ccctcgctga cgattgctac aaaacgacta tatgcgctgt cgatatatgc
    23581 ttgaagcacc gcttcttctt cttttgtctc tggtcgcgtt cctgaaccca tatctttcaa
    23641 cgctccgctt ttaactgttg tatcttccac acccagtttt tctagaagtc ctgaataatt
    23701 caatcctgac atgatcacac caattgagcc ggtcactgtt tcttctgttg caaagatttt
    23761 atctgcttga gcagaaatat agtagccacc gctagctgcc atgtttttca tgctgacata
    23821 cattgggata tcatgttctt tacgaatcgt atccaatttc ttagcgattt ccgcactttc
    23881 gtagacaccg ccaccaggag aatttacttc taaaaagata cctttgactg ttggatcttc
    23941 ttcaatcgcc ttcagttgtt ccataaaatt tttatgattg taaccttcag aagcaaataa
    24001 acctgaagac cctcccgcag caatcgttcc atctactgat aattttacga ttttttgcgt
    24061 actgtctccc tcttccaaca catttgaagc tagttcttca tccccatata accaactgtt
    24121 caatccctca atttgatcgt tttcctgagg cttagtcaaa ctagctgaaa ctaacgaaac
    24181 cacaaataat cctgcagcaa tcagaactgc tgcccaacgt ctcttattca ttctttctcc
    24241 tttctaatac aagtttttta tgacgatcac agtttctgac tgctcagaag tgtcgaaccg
    24301 ctctgctttt tcttcccgcg catacccgga aaacgactct tttgtcaatt catcttctac
    24361 cgtaaactca cgagcttcag caacttccaa ggcatcaggt gcgatttctt ggatgctatc
    24421 ccagccagta tctaaaaata ttttcgtatc atctgataca ccagctgatg cttcgaattt
    24481 ggacaattgt ttttttaaca ttcccagtgt catgatctca atttttgaat ccatttttac
    24541 tcctcctcta tccgattact ttctattgta ccgaactcct gaaaaagatg atagataaaa
    24601 acccattatt ttttgacata aaaagagcat ttgacaaagc atttgatata taccaattta
    24661 ttttttattc tttttttgtt gacaagaaca ttcgcaaaag gttatgattt taaatgtttc
    24721 cagataaaaa acaaaagagg aggatagtta taccttttag gatagcgcca ggtctgtgta
    24781 aacagatgac gaggagaggg tttatcgaaa gattcggcgg atggccctag ggactgcact
    24841 ctacagaaaa tccacaaaaa atatctgcaa agataaaaca aaaggatttt cctgcagctg
    24901 gaagcattca tacgaattca ttatagaaag taggatgttt tttatgtgcg gaattgttgg
    24961 aatgattgga ttaaaaaatg taacaccagg attgattgac ggtctagaaa aattagaata
    25021 ccgtggttat gattcagctg gtatctttgt ctcagatggc acaactgatt atctggtcaa
    25081 agcacaaggc agaattcaaa atttgaaaaa caaaataaat attgatacta caggaaatat
    25141 aggtattggt catacacgct gggcaactca cgggcaacct tctgaagaaa acgcccatcc
    25201 acatacttcc caaagtggac gcttcgtgct cgttcacaat ggcgtaatcg aaaactttga
    25261 agaacttaaa attgcttatt tagcaaatga ccactttatt ggtgagaccg atactgagat
    25321 tatcgctcat ctaattgaaa ctttcgcgaa ggatactaca acgcaagagg cgtttttaaa
    25381 agctttgcgg gtcatcaaag gttcttacgc tttcgctttg attgatcgga cagcacctga
    25441 tgttatttac gtcgctaaaa ataaaagtcc actattaatc ggactcggcg atggattcaa
    25501 tgtgattgcc agcgatgcaa tggctatgct tgctcatacg aaggaattcg ttgagattga
    25561 agatgaagag atggttaccg tcacatcaga aaaagttatt attcaaaatt ttgcaggtga
    25621 catcgtagaa cgttcttcat tcgaagcaca agtagattct tcagatatcg agaaaggtac
    25681 ctatcctttt tatatgctga aagaaatcga cgaacagcct attatcatgc gtcgtatcgc
    25741 tcaaaaatac gtaacagaag acaatcgtgt ctctcttgat caaaagctgg tcgatacatt
    25801 gtctgatagc gatcgaatct atatcgttgc ttgcggaact agttaccatg cggggttagc
    25861 aggtaaacag actctggaaa aattgacaca gatccctgtt gaggttcatt tagccagtga
    25921 atttggctat aacacacctc ttctttcaaa aaaaccattc tttattttct tgagtcaaag
    25981 tggcgaaaca gcagatagcc gccaagttct ggtaaaaatc aaccgtctcg gctacccttc
    26041 acttacgatt acaaatgttg ctggttctac tctttcgcgg gaagcatcct ttacactgct
    26101 attgcatgct ggacccgaaa tcgcagtagc atcaacgaaa gcttatactg cacaaatagc
    26161 tgtactaact ttattagcca aagctatcgg tgataaaaaa gaatttgaaa cttctcttgt
    26221 attcgatatc actcatgaat tgagtttagt tgctaatgcg atggaatcgg tcatcgccca
    26281 aaaagattat ttagaagagt tggcagaagt atatctcagc gatacaagaa atgcctttta
    26341 cattggacgt ggcgctgact acaacgtttc tcttgaagct gctttgaaat tgaaagaaat
    26401 cagttatatc caggcagaag gttttgccgc tggcgaattg aaacatggaa cgattgcttt
    26461 gatcgaagaa ggaacaccag tgattggaat catcagtgaa gaagtgactg gtgcgcatac
    26521 tcgaggaaac ctgaaagaag tcgaaagccg tggcgctaaa acactagtta ttgtctcaga
    26581 gggattagaa aaggaaagtg accagctggt gctaccaact gtccaccctt atctaactac
    26641 tctaaccaca gtcgtaccga ctcaattact tgcatattac gcaacgctat tacggggatt
    26701 cgacgttgac aaaccacgta atttagcgaa atcagtgaca gtagaataat aaaagaacaa
    26761 ggaccagtgt cagacatctg acactggtcc ttgttctttt attttttatg aaaatatctc
    26821 ttaatccagt ccgatttctt ctttgactac tgccgcgatt ttatcgacat agtaattaac
    26881 tttctcatca gtaggcgctt ctgccatcac tcgaagtaat ggttctgtac cggaaggacg
    26941 aactaggatt cttccttctg atcccatttc agcttctgcc tcttcaatca cttttttgat
    27001 tgccggaaca tccatcgcac cgtttttatc acttactcgg atattcacta atttttgcgg
    27061 atagattgtt acctctgctg caagctctga taatttctta cctgtctgtt tcatgatatt
    27121 cagtaactga attcctgaaa gcatcccatc tccagttgtg ttaaaatcta agaaaatcat
    27181 gtgcccagac tgctcgccgc caaagttata atcgtttttg cgcatttctt ctacaacgta
    27241 acgatcacca acttgtgtaa cgacatcttt caaaccgatt ccttccaccg ctttgtggaa
    27301 tcctaagtta ctcatgacag tcgtaacgat cgtatctttt ttcaatcgat ttttttctgc
    27361 caagtatcta gcacagataa acatgatttt atcaccgtcg acaatgtttc caagttcatc
    27421 caccgcaata atacgatcgc catcgccatc gaaagctagt ccagcatctg ctcctttttc
    27481 aacgaccatc tcagctaaac gttctggatg ggtagagcct acgccatcat tgatatttaa
    27541 cccgtctgga tttgtgccca tggtataaaa atctgtttca agatcggcaa acaaacgatt
    27601 aacacttgtt gaagttgctc cgtttgctgc atcgacacaa atggtcaaac cggaaaggtc
    27661 accgttgatc gtttgtacaa ggaattgaga atatttcaat aagccttctg gaaattcttc
    27721 tacagttccc aatccttcag ctgatggacg aggcaattca tccacttcag catctaataa
    27781 tgcttcaatt tctagctctt ggtcatctac tagtttaaaa ccatctgcac cgaaaaattt
    27841 gattccatta tcttgtgctg gattatgaga agcagaaatc atgacccctg cgcttgcttt
    27901 ttgcaaacgt gtcagataag caacacctgg tgtagagatc acacctagct ggaacacttc
    27961 gatacccacc gataaaagtc ctgaaatcag cgcttcttct aacatttgac ctgagattct
    28021 tgtatcccgc cctactaaca cgcgtgggcg ttttccttct tcttcatgct ggcttaggac
    28081 ataacctccg caccgtccca gcttaaatgc aagttctggc gtaagttcct tgttggcttc
    28141 accgcgtacg ccgtctgttc caaaatattt acccatagtt gtaaaattac tcctttaact
    28201 taattttctg aggaatttgt tctgctcatt tgtgttgatt cgcttgtttc tgatgtttct
    28261 tctgtacttg tggtcgagct gcttgtccca gattccgaac tggaagaaat ggttgttgtc
    28321 gatggttccg ttcctgaatc agcagatgaa atacttctac tcgtacttgt attttcttgt
    28381 gtccgactgc tcgtcgaagc agagctactg cttgacgttt gcaacacggg tgtaatctcc
    28441 acactaactg attcgggctt gatacttaac ccctcttcta ctggtatttc aattttacga
    28501 gttgttcgat gattgatacc tgagacattg atcggtacag caatactgtc accgatcgat
    28561 gcaagcaaat cgctagagcc gcttacttct gcttccagtt ttgaaaaact gaaatcatag
    28621 ctttctaccc cggcagctgg tgttccttgc tgtatcccat aaagtcgtac cgacttgctt
    28681 ggcttgatcg aatcagctct cactgttact tgcactggat cagagacgat acttaatact
    28741 tcccctgctg cattcagcgc ctgtattggg acctcactat taatcccatc atctgtgacc
    28801 atcgaagcgt ccacatcagc tactactcgt ttgatttctg ccaatgtttt gtcacctgta
    28861 gtgatagaga cttttttagg actaacggaa gtatcatcaa gttcatatcc agatggtgtg
    28921 aacgttgaag gaatcaacgt ttccacatcg aaatctttta ttaccttttt ctcaaccgtt
    28981 actgtaatag tcgatggttc gatctttgct gtgacagcac tgctcaaatt ttgaattttt
    29041 agcggaacct catgtgttcc ttcgcccagc ttagtgatat ctgctgtgac gcggaacatc
    29101 cgtgtatctt cgtttgcctc tgcattcaac tgaactcggt ttgcactgga aagtttgaca
    29161 gtcactgcat tttcatatcc atggatatag tagcgctttg aatcataaga aatcttgatt
    29221 ggcaccccag taactgtttg attatacgct tcatttccag aaagcgtatt tggaacggac
    29281 tggccatttg cattgaagta cagcgcaata ctgaacagca atgcaataaa actgtaaaga
    29341 atgcttgtcc gtttctcttt tgagatcatt tgcgatcccc tcccttagtc ataccgtcta
    29401 ggaaagattg aatcacgttt ttcttgtttt ttgttttctc ttcagcaatc agttctctac
    29461 gcaaaattgc caaatattct tgctgggata agccagccat cagttcatta tctaatgtaa
    29521 tgctgacatc cccagtttct tcagagacaa cgatggtaat cgcgtcgctg acttcgctta
    29581 taccgacagc tgcccggtgt cgagtcccga attcttttgg aatcaacata ctttctgata
    29641 gaggaagata ggcgcttgct actgcgatct ttccttcttt tacaataact gcaccgtcat
    29701 gcagcggtgt attaggaata aagatattga tcagcagctc tccagtgata tctgcatcta
    29761 atgcaattcc tgtctcaata tactcatcta atccagtatg ccgttcgata gtaattagcg
    29821 caccgatttt tcgcttggac atatattgga tggctttgtc aaaagacaag atcatcttct
    29881 catcttcctg ctgttcgctt tttgattgtt tgaaaagcga actgcgtcca agatgttcca
    29941 gtcctctccg gatttccggc tgaaaaatca cgatagcagc tatcaccccg tacgtaatga
    30001 cttggttcat cagccaagac aaggtgtgca gaccaatgat ttccgctacg attcggataa
    30061 caataaaaat agctacacct ttcagaagct gaatcgcttt tgtgcctcgc agcagttgga
    30121 tcagtttgta tacaagatac cagacaacca gaatatcaag tatgttcacc aaaaaattca
    30181 gagagaacaa gtcaccggaa aacatttgct gccaatagtc caaattaaaa agttccccga
    30241 tttgaaatga cataaaaagc ctctcttctc ttttgagatt tcctctctag tatatcatat
    30301 gttttaattt tagaggctga tctgctcgta tttttcttga gaaaaacgca taattttcag
    30361 gaaaattgca agtatgcgtt ttatttttct ctgcaataaa tatttttaaa cttcagagaa
    30421 ttattcatta tattttttct gttatttttc ctttttttct tttgtagctt gttccatttt
    30481 tttacgtcgt tctgctctgg cagctcttct ttcttctgct tcaaggtccg tcgttttttc
    30541 ttttctagtc ttaacgggta catcgataga ttcctctggt tcaagtcgtt tcttgatttt
    30601 ttctaattct cccgtcagtg cagcatagtt gtaaaaacgt gttttagcgt cttggatagt
    30661 cttttcaaat aaagcttttg caagatttgg atttgcgttc tctagcgagg aaaagcgaac
    30721 ttgtttcctc atgaaatcag gcatagcaga gaaatcaggt tttttgtagt ccaaagtcat
    30781 tgggttcttg tttttttcga ccattgcagg gttatatcga tataatgacc aatagccaga
    30841 agaaacagct tcttttgctt ctttaagcga ttctttcatt ccaccaagca aaccatgtgt
    30901 gatacaaggc gtataggcaa tgattaaaga aggtccagga tacttttctg cttcttcaaa
    30961 agcctttatc gtctgcattt gattggcacc tgaagcaatt tgcgccacat aaacatttcc
    31021 atatgtcatc gccatcattc ctagatcttt ctttgaagca tactttccac tagccgaaaa
    31081 tttagcgatt gccgaagctg gtgttgcttt tgaggtttga ccgccagtat tggaatagac
    31141 ttcgttatcc aaaacaagaa tattcacgtc tgctccgctg gcaagtacat gatcgatccc
    31201 gccaaaacca atgtcgtaag cccatccgtc tccaccaatc atccattggc tgttttttac
    31261 gaatagatcc tttctcttgt atatatcctc cagttcaggg acaattgatc gttcgctttc
    31321 gatcgcagct tgcagttttg ctgctctttg ctgcgttcct tcgctctcaa acatgtgtac
    31381 caaccagtct tccatcaatt ctcgtagttc ttctgatact tttggcaata cttctttgat
    31441 tgaacttgcc aaagcctcgc gacgagtctg tgccgctaga agcataccat aaccaaattc
    31501 agcattatct tccaataaag aatttgacca tgcaggccct tgaccacatt cattggtcgt
    31561 ataaggagaa gcaggagaag caccgcccca aatagaagaa cagcctgtcg cattcgcgat
    31621 catcattcga tcaccgaaca tttgtgtcaa taattttaca taaggtgttt cgccacagcc
    31681 tgagcaagcg cccgagaatt caagaagcgg ttgattgaat tgtgtagaca agacagtatt
    31741 ctttcctttg actggatttg ctttttgtct taatgtcatt gcaaaagccc aattcacagc
    31801 ttgttctttc tgttcttcat aaggcttcat cactaaagct ttttcttttg cgggacaagc
    31861 ctctacacac agaccacaac ctgtacagtc ttccactgaa acttggatac ggtattttac
    31921 gccgtctgcg cctcgcattt ctctcacgat aaatccttct ggcgcttctt ccatttcctc
    31981 ttcatctgct aaaaatggac ggatggcagc atgaggacaa acaaaggcac attcattaca
    32041 catcgtacag cgatcactaa tccactcagg tacttctaaa gcgacgcccc gcttttccat
    32101 agaagccgtt cctaaaggca tttcgccagt tgtcattcca tttgctacaa gtgtaccaac
    32161 agagagttga tttccttcct gtgcattcac tggttcaagt atttcttgta tataaccagt
    32221 gttcctttta ttgatttttt caggcatctc caacgttctc caatggtctg ggatcgcgac
    32281 ttgatgaagc agttcggtcg tccgatcgat tgcttgtatg tttttttcta cgatagccat
    32341 tgatttatgt ccatagcttt tcagggcttc ttcttttagc agcggaagca cctcatcaaa
    32401 aggaatgatg tcagctaatt taaaaaaagc cgtttccatt gccgtattga tccggcgtcc
    32461 caaaccgact tcttgggcca atctcatggc attgatcgta tagaatctaa tgttattttc
    32521 agccaagtaa cgttttaatt ttaagggcag atgcgtttct aattgttcgt cgctccaaag
    32581 agtattcaat aaaaaaatgc cacctggctt caatcctttg accaagtcat agctatgcag
    32641 gtaagctggt gtgtgacagg caacaaggtc cgcatgctcg acaagatacg ctgaacgtat
    32701 cggcgtatct ccaaaacgaa gatgagagac agtcagaccg ccagattttt tcgaatcata
    32761 ataaaaatag ccttgcgcat atttatcggt gtgatctcca ataatcttga tagctgattt
    32821 atttgctcca actgttccgt cagatccaaa tccccaaaac ttggcctgga atgtttgcgg
    32881 ttctgtcaaa tccagacttt cctttggttc caaagattga taagtcacat catccacgat
    32941 ccctatggta aaccgttttt tgcgtatgct tgggtctttt ttcaattcat caaaaactgc
    33001 tgagatttgg tcgggagtca catctttaga ccccaatccg tagcgaccac caataacagc
    33061 cgggcgaagt tcagaatcat ataacgcact ttgaacgtct aataagagag gttctccacc
    33121 tgcccctggt tctttacttc gatcaagaac agcaattgtt tttactgtat gaggcaactt
    33181 ttgcacgaat gtttccactg gaaaaggacg ataaagatgg atattcaaaa aacctgtttt
    33241 ccgtccgttt gcattcaagt aatcaatcgt ttgttcaatc gtctgtgcaa ctgatcccat
    33301 agaaacaatg acttcttccg catcgtctgc tccgtaataa gtcaccaagt cataagaagt
    33361 tcctcgtaat cggttgatct ctttcatata tttttgaacg atttcaggta atttatcata
    33421 ataggggttg atcgtttccc gttgttgaaa atggatgtct ggattctggt tcgtaccact
    33481 aacagtcgga tgattgggat tcatccctcg tttacgaaat gaagctaatt tctcctgatt
    33541 gatcagagga gctaattctt catattccaa aacttcgatt ttttgaatct cgtgactcgt
    33601 acggaatcca tcaaagaaat tcaaaaaagg tacttctcct tcaatagaag caagatgggc
    33661 aacaggtgct aaatccatca cttcttgtac actgctttca gctaacatag caaatcctgt
    33721 ttgtcttgca gccatcacgt ctccgtgatc tccgaaaata ttcaacgcat ttgtcgtcac
    33781 tgcccgacta gcaacatgga aaacacttgg cagtagttcc ccagcaatct tgtacatatt
    33841 cggtatcatc aaaagcagcc cttgagaagc ggtatatgta gttgtcagtg caccagtttt
    33901 caatgatcca tggaccacac cagctgctcc tgcttcggat tgcatttcta ctacttttac
    33961 tggttgaccg aatacatttt cttttcctgc tgctgaccat tgatctacta attcagccat
    34021 ggtcgaactg ggtgttattg gatatattgc agcaatctcg gtaaatgcat aagaaatata
    34081 tgcggctgcc gtattgccat ccattgtttt catttttcgc atgattcatc atccttgttc
    34141 atattctctc ttattatctg ttccattata acgtaaaaca ttccattttt tcttttattt
    34201 ataaaaatat ttcacatatg tctatttgaa ttggtcatct aatttttaga caaacagtct
    34261 aaatcgttgc ctttttttgt cagacatgta taaactataa gcgaaagagg tgttttaaca
    34321 tggatatatc agtgattgat gcaacgaaaa caaatacaca aaaaggaatc ctttatggtt
    34381 catcgaatgc tcctaaaaaa atggtcgaat tcatcaacct atcttgtccg tattgccgac
    34441 aatggtttga agaatcttat gagctattag aagaagcagt ccaaagcggg caattgcagc
    34501 gagtgatcaa attgttcgat aaagaaaaag aaagcttgca gcgaggaaac gtgatgcacc
    34561 ggtatctcac aatcagcgat ggtcaaaaag cgatcaaaga gatcaaacaa atattcgata
    34621 ctcaagacga gtggaaacat ctttctctcc aagaagtagc ggattttgca gtagataaac
    34681 taaagctgac agaacaaaaa gacgaacagc tgagccaagc tgtcatcaac gaagctgagc
    34741 aagcacatat tcgatttgtt ccgactgtca tcttgggtaa agaaatcttt gatgaatcta
    34801 tttcaataga ggaattaaaa gaattgatcc aaacaaaata aaaaaataag gagcgtagga
    34861 caaaagtaaa gaacactttt gtctcacgct ctaaacacct ataaacggcg gaagcagaag
    34921 caactccttc ttatttcttg gagttaaacg cttctgtccc agcctcctta ttccgaataa
    34981 atggtgtcca aaagcttgca tctgccagat tatctcattt cttatgacaa gctgagcaaa
    35041 ttatctccac caaataattt attcatattt ttgacttgcg catactaact aattcttaaa
    35101 ttttcataca aaatttctca aattccctta acgagtaata tttatgtacg gtgattcaca
    35161 ctagtatccc aatcactttt taagttatcc cgatttcaat tctacttcaa aaatagttgc
    35221 ttttatgtat gctgttagtt gattagatgg tcgtttgttg agctaggtcg tttattttaa
    35281 acaagttgtt tctttagctt atacctatct cgtctaccaa acgcaagatg gcaaacacaa
    35341 atgcatacgc atctgtattt gccactttga ttcgtataaa gctaacaact cctaactcct
    35401 ctcatttaat agttgctctc ttttttattc agatacattt ttgctgatca cagcctagta
    35461 tttcaatggt tttgaacact aaaccaaatt gttccattac aacattcact ggctgatgaa
    35521 atggattaat agatttcgat tattcaaagc gattttctat tggtggattg tgttcccaac
    35581 taacaagacg gattccaaag tcattatata actcttcaag agttaaccct ttcctgttcc
    35641 caatagatgt atctctccca cgctcgatat aaaatatgga gtttcgaatg ccaagacctg
    35701 gcaaatcttt ccttgttaca gttacactgc tactaacttc cccatataaa atccagctcc
    35761 tccaaaatga taatatattt ttcgaccatc atctaactca tgtaacaata attgttgtgc
    35821 cctcttgtca ctcgccaaat gcaaacgcca cgtgcgatac catgccatgc tacctgcatc
    35881 tgcagaaaat ccatcaaata atgcaacaat tgtatcttct atcacaatcc tttccccatc
    35941 tacttcatat tctaatctaa aatcaaactc ccctcgggta atcgcaggtc ttggtggctt
    36001 aggacccaat attattctac ttaaaaccgc attcgttccc agatgaaaca cagctataac
    36061 aacaataatg attaatattt tgtttctatt tgataaattt ctcattattc gcaaatcacc
    36121 tctacattct cacatactag ttcgtaatac tcctttaata tcaaaatatc tactgatcgt
    36181 aataatattc gctatgaatt cctactactc gtataagaaa ggccaaatca tcagctttta
    36241 cttgctgatg atttggcttg tttctattta tcgtaattgt tttctaatca ccaaaattgt
    36301 taacaatcgg ttcagatatt tcccaattca ctagccttat attatattga tttaacaatt
    36361 cttcttcatt tattgtattt tgatcaagcg gaccaaattg ttctaataat tctttgtcat
    36421 gtaaaatatc ccttctagta atgcctcttt ccctttcaat gaaagaagca ctaggaaaag
    36481 tatgattata accattcaac ctatctccca tgtaataatt agcaggtcct ggaaaataaa
    36541 atatttgctt attatcacta acttctaaca gcaacactaa atcttctccg ctggctaaac
    36601 gacttgtcca tctacgatat ctccctatgc cttcgttcat tccaaatcca tcaaattcaa
    36661 ctattaacgt gtcttctatc acatgtaatt cttcattcaa ttcatactca agtctaaaag
    36721 gaaattctcc atatgtaatc tctggcaatg gtggtgctgg agttctccaa ataaatacaa
    36781 taactgtgaa tagaaaaaat ccaacgatcg atataaatgt tatgagacct gctcgaagta
    36841 aaacccgata taataaaaat gctgtatttc gctttgctat atctagaaaa ataaaaagta
    36901 ctgcaatcat aatgatagta aaagttgtaa aaaaacgcat ttttgccctc cctttataaa
    36961 catcgattct caaattctaa accaaatctt ggtagttcaa gttcaggtat aacgtattcc
    37021 aaccatacat ctcaattact atttatgaac ttatgattat cactgaataa atcactccat
    37081 ccccttgtta aaacttctac attaattaca cctggttgtt ttcgactagc taatccaatg
    37141 aacttatcaa ccatccttat ccaccaacca cgagaatctt gaccagaagt aagaagagca
    37201 gttctcaagg atgatcgagc agttccttcc agttttttaa ttaatcaggc cagttataga
    37261 taaatacttg atcttatcta tatcaggact tctatattaa gcaaaaattt atgtacaaaa
    37321 ctaaaatctt cattcagttg tctccccgct ttttatacga ttgtattaaa aacaatagaa
    37381 gcctttccaa attatgttac tccagtaaag atggaattat agtttgacgg aagaaaagca
    37441 agtataactt ttaaaaaaaa ctgatacatt cgcatctcct gcttcatgta tcagtttttt
    37501 ctttggatta aactgcttct tcacgcagtt tttccgcaaa ttcatttatt ttgcgaattc
    37561 ggtgattaat tcccgatttt gatatcgcac ctgagggaat catttcccct aattctttca
    37621 agctgacctc tggatgttga agccgaagtt ctgcgatttc ctgaagtttt tcaggaaggg
    37681 catgtagacc gacctttgct tcgatcaatt cgatgttttc gatttgttta gaagccgcat
    37741 caatcgtctt gttcagattt gctgtctcac aattgactag acgattgacc gaatttctca
    37801 tatcccgtac gattcgaaca tcttcaaatc ggagcattga gttggttgca ccaatcaatg
    37861 ttaagaaatc agcaattttt tctgctcctt ttaaataaga aatatagcca ttgcgccgtt
    37921 caagcgttcg agcatgtaga ccgtaataat ttaacatatc gcaaatgtct tggttatgct
    37981 gttcataaat agaaaatatt tccaaatgat aacggctcgt ttccggatta ttgactgaac
    38041 ctgaggccat aaaagcacca cgtaagtaag aacgcatttt ttgcgaattt cccataatct
    38101 cgtccgaaac gtgtccattg aacatcatac catccatgat atcaagatcc atcaacacat
    38161 cttttgtgcc ttgcttcaac cggacgatat agacattgtt cttttttaat ttcatttttt
    38221 tacgaacgag tagctcactt cgtacctgat aatgatcttt caaaagagaa tagatacgtc
    38281 tggcaattgc agcattttct gtttggacgt tcaaaataaa ctgctggttc acaataccta
    38341 aagagccgtt cattcgcagc aaagcagcta attccgcttt cgcatgttct cgatgaactt
    38401 ccaaaccagt tagttctttc ttcacatctg cagcaaatga catcctattc tcctcctttc
    38461 tccaacaata aattgcttaa tattttgaac cgaaaactaa acggaacaat tcttctacta
    38521 ctttgtctcc atcgtggaag acaccaccat ctttcaattc caaaaagtcg gtggaaatca
    38581 ctcgacatcc ttcatttctc aatccgttga agtcgtgtgc gacttgtact agatactcat
    38641 catagatctc tgggtccata taatcttcag gcactttttc cgtattgacc aatactgtat
    38701 cgataaaagg ctgattcaaa tgcttgtgta aaacacgtat atgatcggca tctgtgaaat
    38761 gttccgtttc ccctttttgg gtcatgatat tacagatata gacggtttca gcagttgtct
    38821 tgagcattgc ttcgccgatt tctggtatca ctaaatttgg aaggatactg gtgaataaac
    38881 ttccgggtcc caaaacgacc atgtcggcgt ccataattgc tgaaacgact tttcgagccg
    38941 ctttggcttc acttttatca tttgtgttgc agacatacac acggtcaatg gttttacggt
    39001 cgatcgcgat tttagattct cctactgcag tcgttccgtc tttaaagaca gcatgcaagg
    39061 tcaaaggagt ttctgaagaa ggataaacat gtccatctac atgcatcatt tttgctaata
    39121 attgaatcgc ctcataagtg cttccccgca tctcggaaac tgcggcaatg atcagattac
    39181 cgatcgtatg attggctaaa aactgatctt cctttttgaa acggtattgg aaaatatctt
    39241 catagaattg tggcatatcc gataacgcca ctaagacatt tctcaagtca ccaggaggag
    39301 ccatagcgat cgattctctg attgcaccgc tgcttccccc atcatctgca acagtcacta
    39361 ctgctgtgat atctgctcct tgatttcgca aacttttcag gataactggc agaccagtgc
    39421 caccgccgac cactacgatc tttggttttc ttatccggta ggttttcatt ttcacgaccg
    39481 gttcaccgtc tctttccttt tatccttgtc ccgatgtgtc acattgactt tatagttttt
    39541 ccctaaagca tttgccaaac gttcagtcaa tgccacagaa cggtgttgac cgcctgtaca
    39601 gccgattgca actgtcaagc tgctttttcc ttctttaatg tatccaggca atacagtttc
    39661 cagaagatcc aaaaatttat ggtagaatga ttgcgtttca tcaaaggaca tcacataatc
    39721 atagactggc tgatcttttc cggtcaatgg tcttagttcc gggatataat gagggttggg
    39781 caaaaaacgc acatccatca caatatccga atcgatcggc aacccgtatt taaaaccaaa
    39841 tgatacaaat tcgatccgaa atccttggtc tccctttgat ttgaatgact cattgatttt
    39901 ttcacgtaat tgtcgtggtg tcaatgtcgt cgtatcaatg atcacggaag cttgggcttt
    39961 caagtcgtct agtatcgccc gttctttacg tatcccttca gtgatcaaac cgtccatcgc
    40021 cattggatgt gctcgtcttg tttctttgta gcgagccact agttcttcgt ctgaagcatc
    40081 taaaaataag atagaagtgt cgatgaagtt cgtattttcg atttcgatca gcatgttttg
    40141 gatttcttca aagaaggaac gagaacgtaa atccactcct aaagccattt ttgtgacttt
    40201 gcctgattct ttgattaatt cccagaattt tggaatcaat cgaggcggca tattatcgat
    40261 acaaaaatag cccatatctt caaaactttg gatagctact gttttccctg caccgctcat
    40321 acctgttatg atgactaatt gcaaattatc tgtcataatt acgaactcct ctcacattgt
    40381 gcatagtaaa attatatcat tccgggcgta tcattaccag ttttcttttt cttttacaaa
    40441 aagatttgga ccaaatatct tttaggatat ttgccccaaa tccaattttt ttacttttcc
    40501 gatgctgtat ccaatgcctt gcttctttca gctagcgctc gttcaatcgt ccgatctgct
    40561 aaaatagatt gggcatcgat cactggataa tggttatctt cagcaaattc atgcatcaat
    40621 gacaattctg tgcaacctaa gataactttt tcacagttta ggcgctctac cgcttcttct
    40681 aagatttcgt aatatagctc ttgattcaaa taatccgatt ccttgatctc atgatagatc
    40741 agataattga ttttttcttg aagaacagta tcaggaatca ctgtttcgaa tccaagattt
    40801 ttgacttcgc gttcatagat tccagctttc atacttcctt ctgttcctag aatcgctact
    40861 ctccctgtcg tatgctgacg gacaagttca tttgctgctt ctcttggcat atgaaggata
    40921 ggaatatccg ttgccgcttg taattcttca aaaaagtagt gtgcggtgtt acaagtcaac
    40981 acaatgaagt tcggctgcaa taaattttgt ttctcaatat catccagcag aaacggcatt
    41041 ggattttctt ctgatcgatc taaaatataa gctgtacgat caggaactgt tgcatgattg
    41101 aataagacat aattcaaata ttcttgatct tttgtagctt tcgttcggtg gttgatcaag
    41161 cgaacaaaac tttctgtcgc catcgtgccc attccgccta aaatactgaa aaaattctcc
    41221 atgaactagc cttctttcac atgaaaatac tttttgaatc ttggaatata gttatggaac
    41281 atatatttca tcaacaacca gcgcttgatt gaccggtctt tttcataaaa cacagtagta
    41341 ccgtaacgat tttctttgat catttgctca gctagttttt tgtcttcatt ttcccgagca
    41401 tattctaaaa agattttttt gggcacaccc atccataatc ttgctttatc tgattgattc
    41461 gttccatagg tcgtttcaac aaagggtttg ttaaacactc gatcttctgt gacgaaacga
    41521 gccagattca agccgttcaa tgtcacaaag aaactgctac gaccttgtct caaattgatt
    41581 tcaaataatt tatattctcc atctctagga tcatacttca tatcgaaatt ggcaaagcct
    41641 gtatattcga ttttttccaa aaatgcctta atggtttgat agattttttc gttataatct
    41701 ggcatgatca caacgtaatt accaatcgat gctggtgtag gatcttctaa cagtggatga
    41761 ccaagacaca tcatccgaac ttgatgatct tcatctacat acgcatttag cacacgcata
    41821 ttactatcat cacccgggat aaaatcttgt acaatcattt cacttttata accggcttcg
    41881 tatatccggc ctaaaattaa atcgaactct tctctagtct ctaaaataaa agcttttttt
    41941 cttccttcaa attggacaga aagatactcc acactgtttg caggtttcaa agcaactggg
    42001 aattcaaaag gcaattcctg ttccaaatgt ccatttacta acatttcttc tctgacgatc
    42061 aatgttttag gatacggaag atcatattct tcacaaactt cataaaagct tactttattg
    42121 atcagtcttt caaataaaga ataatcaata tatggacaga taaaatattc tgacagctct
    42181 tgtttatgtt gggagatcaa ttctgcatat ccatcaccac aagcaatcaa aagatatttt
    42241 ttactcttat cagaatatct ttcttttgcc aaacgaagca tcgtctcgat aaacacaggg
    42301 tctttatcaa atcctggaat aacttctaca ttgacaattt tactgtagcg ggtaggggct
    42361 aactgatccg aagcatatgc ttggcagatt ttgccgtatg cttcattaaa agaacgtgcc
    42421 ataccataaa cgttcatgtc gcttcctaat aatataggga taaattcttc attttcaata
    42481 ctgttcatca ttatctctca cttactcata atctcttgtt tttcttttcc aactacacaa
    42541 ggaatatcat accataaaga aaaaagcaat caaaggaaac tcctccgatt gctcaattct
    42601 tttttgaacg gattgaactt ataggaagtt tttgtctata ccaatcagtg tagaaagaac
    42661 taccatgtaa tgattctaga acactgatat taataaaaca agcaaaaatt cattttttta
    42721 tgttttttta actatctcag ctatctatcc tctttatacc attatttttt tcaaatagtg
    42781 acctgtataa ctttctttta cgttaatgat ttcttctggt gttccagtcg caaggatcgt
    42841 tcctccacct tctccacctt ctggtcctaa atcaatgata taatctgctg ttttgattac
    42901 atctagattg tgttcaatca ctaaaactgt gttaccagca tctactaatc tttgtaatac
    42961 atgcaacaag cgggcgatgt catcgctatg aagtcctgtc gttggttcat ctagtatata
    43021 gaaattcttt ccattagaga ttttgtgcaa ttcactggca agtttcatcc gttgtgcctc
    43081 accaccggac aatgtcgttg ctggttgccc catcgtcaca taacctaagc caacatcaac
    43141 aatcgtttgc agtttgcgat gaatctttgg aatgtgcttg aagaattcta cagcatcttc
    43201 tactgtcatt tccaaaatat cagcaatgct ttttcctttg taatgcactt ctaatgtttc
    43261 agagttatat cgtttgccat gacatacttc acaaggaaca tagacatcag gcaaaaagtg
    43321 catttcgatc ttaataattc catccccgcg acaagcttca caacgaccgc cttttacgtt
    43381 gaaactaaaa cgccctttct tataaccccg catttttgcc tcgttcgttt gagcaaataa
    43441 cccacggata tcatcaaata cacttgtata agtcgctgga ttacttctcg gcgtccggcc
    43501 gattgggctt tgatcgatat cgatgatctt ttcgatactt tcgtagccgg aaattgtctt
    43561 gaatttacct ggcttagcag aattcttatt taatttttgc gctaacgatt tctttaagat
    43621 actattgacc aatgtactct ttccagaacc agacacacct gtgactgcta caaattctcc
    43681 taatggaaat tcaacactaa tatttttcag attgttttct gaagcaccag tgatcttgat
    43741 tgctttccca ttacctttac ggcgttcttt tggtacaggg attgattttt tccctgaaag
    43801 atatttccct gtcaaagaat tttcatcatt agctacttct tcaggagtgc ctgcagccac
    43861 gatttgtccg ccttgttctc cggccccagg tccgacgtca atcagataat ctgctgccca
    43921 catcgtatct tcatcatgtt cgactacaac gagggtgttg ccaagatcac gcattttctt
    43981 taatgagcca atcagtcgat cgttgtcgcg ttgatgcaat ccgatcgatg gttcatctaa
    44041 aatatacaaa actccagaaa gattcgatcc aatttgtgta gccaatctga ttcgctgcgc
    44101 ttctccccca gataatgttc cggaagcgcg actcaaagtt agatagtcta gtcccacatt
    44161 ttccaagaat gaaagtctgt catttacttc ttttaaaatc ggtttggcaa ttactttctc
    44221 ttgttcagat aacgttaagt ttgagaagaa atctactgct ttttgaatag acaactcatt
    44281 tgtttgcccg atattcgttc cattgatttg aacagataga gcttggggat tcaatcgata
    44341 acctttacat gtctgacaag ttaattctgt catataaaga cgcatttgct cacgcgtgaa
    44401 atcactgttc gtatcatgat aacgacgctc gatattcttc aatacccctt cgaaagtcgt
    44461 ttctacatcg cgaacgccac caaaatcatt ttcataatgg aaatggaaaa gatcatctgt
    44521 cccattcaag atgatatcct gatgctcttc cggtaattct tcgaatggtg tatctaaatc
    44581 gataccgaaa ctttcacaag cctgcgctaa catttgagga taatactgag agctgattgg
    44641 attccatgga acgatagcac cttgactaag tgtcttcgtt ctatctggaa tcactaaatc
    44701 ttgatcgact tctaatttga cacctaaacc atcacagtct ggacaagctc caaaaggcgc
    44761 attgaatgag aacagtcttg gttctagttc gccaacagta aatccgcaat aaggacaggc
    44821 atagtgttcg ctaaacaaca tttcttcttc accgatcacg tcaaccagag catagccgtc
    44881 tgccaatcgc agagccgcct ctaaagaatc aaatagacga gaacgaatcc cttctttcac
    44941 aatgatccgg tcgatgacga tcgcgatatc atgttttttg tttttctcca gctcaggcac
    45001 ttcacttaaa tcatagatct caccatcgac tcgaacgcgg acgtatccct ctttttggat
    45061 tcgttcgaat atttttttat gttgtccttt tttctttacc acgatcggtg ccaacacttg
    45121 gatctttgtg cgctcaggca aagccattac ttgatctgcc atttgatcta ctgattgact
    45181 ggtaatctcg atatgatcgt tgggacaaat cggatgtcct acacgtgcaa acaacaagcg
    45241 taaatagtca ttgatttccg tcacagtacc tactgtcgac cgaggatttt tacttgttgt
    45301 tttctgatca atagaaatcg ccggactcaa tccgtcgatg ctatctacgt ccggcttatc
    45361 catttgtcct aaaaactgac gagcataagc agaaaggctc tctacgtatc tccgctgccc
    45421 ttcagcgtac agcgtatcaa atgctaggga actttttcca gaaccggaca aacctgtaac
    45481 gaccacgaat ttatctcgtg gaatcgttac atctatattt ttcaagttat gggcacgtgc
    45541 accgtgaatc gtaattttat cgttagccat gttgtcctcc tactttgaag cttttaattc
    45601 taaaatcata tctcgcacat tagcggctgt ttcaaaatcc aatgctttcg ccgcattttt
    45661 catttctttt tctaatttca tcaataacgt atctttttct tctttcgtca tttcttcata
    45721 cgagacttgt accgcttctt ttgtatcatc ttccgattct ttcgtaatag aaatcaaatc
    45781 tcggatttct ttaatgatcg tttttggaac gatcccatgt tcttcattgt acttctgctg
    45841 aatcgtacgg cgtcttgatg tttcatccat cgctagacgc atagaatctg ttactttgtc
    45901 tgcgtacatg attactttac cttcttcatt ccgagcagct cgtccaatcg tttggactaa
    45961 ggaacgttca ctacgtaaaa agccttcttt atccgcatcc aagatagcaa caagggaaac
    46021 ttcaggtacg tctaatcctt cacgaagcaa attgattcca actaacacat caaattcacc
    46081 taatcgaaga tctcgaatga tttctgttcg ttccagcgtt ttgatatcac tatgcaaata
    46141 tttgactttg atccctaatt ctttgaaata atctgtgagg tcttctgcca tttttttcgt
    46201 caatgtcgtt acaaacaccc gctggtcttt ttcgactcgt tcatttattt cgcctactag
    46261 atcatcgatt tgtcccatga ttggacgaac ttcgatcact gggtcaagca gccctgtcgg
    46321 acggatgatt tgttggataa cggtatctgt ttgttcatgt tcatatggtc ctggcgtcgc
    46381 agagacataa atgatctgat tgacatgttt ttcaaactct tctaaccgaa gtggccgatt
    46441 gtctaaagca gatggcaaac ggaaaccgta atctactagc atctgttttc tcgctcggtc
    46501 accattatac attcctctga cttgaggcat ggttacgtgc gattcgtccg ccacgatcaa
    46561 aaaatcttca ggaaagaaat ccaatagcgt ataaggcggt tcaccttctt tacgtccgtc
    46621 catatgccga gaataatttt caattcccga cgtgtagccc atttctaaca tcatttcaat
    46681 atcgtaattg gttcgctgtt ctaaacgttg agcttccaga agtttgtttt catttcgcaa
    46741 gacagttaaa cgctgttcta attccgcttt gatattcgct acggcatgct ccatatgttc
    46801 atcattcgtc acaaagtgag tcgccgggaa gattgccacg tgttccgttt ctcctaaaac
    46861 ttcacctgtc agtgcattga cttctcggat acgttcgacc tcatctccaa aaaactccac
    46921 acgtaaggca cgttcatctc ttgaagccgg aaaaatctcc acgacatcac cgcgcactcg
    46981 aaaacgaccg cgctgaaaat ctatatcatt tctttcgaat tggatactga ctaagtcacg
    47041 aatcaactga ttgcgatcta gttctgctcc ctgtcgaatc gaaactactt gtttttggta
    47101 ctcaaaaggc gaacctaatc caaaaataca tgaaacggat gcaatgacga tcacatcatt
    47161 tctttctaat aatgaactag tagccgaatg tcgtaatttg tcgatctcat catttacact
    47221 tgaatctttt tcgatatacg tatcgcttga aggcacataa gcttcaggct gataataatc
    47281 ataataagaa acaaaatatt caacagcatt gttagggaaa aattccttga attccccgta
    47341 cagctgacca gccaatgttt tgttatgggc aataattagt gttggtttat tcactttctc
    47401 aataagattg gaaatcgtat atgttttccc tgttccagtc gcacctaata agatttgtgc
    47461 ttttttcccg ccgactacgc catccactaa ttggttaatc gcttcaggct gatcaccagc
    47521 cggttggtat ttcgagacaa gctcaaagtg tcgggaggta tctctctcaa tcattcttcg
    47581 tcctcctttt cattcattcc ttttcatttt acgaccaata aaaagaaaag gaaagcaaag
    47641 gcattcctta ctaaaaaatt ataccacacc gaacatactt tcgccacttt tttatcttat
    47701 tatgcatgtt acgttttata acataaaatg ttagaaactc gcattttttt cattttttcg
    47761 agcttacagt cttgtctgat tcagcacttt tcgcctataa taataaaata ttggaaattt
    47821 aggaggttga ttatgaaaag aaagcattta tttcactcat ttgttttctt aatgacagga
    47881 cttgtgacac ttgcgtttgg acatgttgca caagctgaca acactacaac ggcagagtca
    47941 agcacaagcg agacaatgca aaaaatagag cccaaaaaag acgtatacgt aattgccagt
    48001 gactctgctt ttgctccatt tgaatttcaa aacgcaaagg gcgagtacga aggcatcgat
    48061 gtaaaattga tggaaaacat cgccaaactg caaggattta acatccgaat ggactaccgt
    48121 ggtttctctg ctgctttgca agctttggaa tcaggacaag cagacggaat gattgccgga
    48181 atgactgtaa cagatgaacg aaagaaaagc tatgattttt ctgattctta ctttgatagc
    48241 gggatccaat tagctgtcaa aaaaggagat acttcgatca agtcttatga agatttgaaa
    48301 ggaaaaacag tcggagcaaa agttggtacc gaaagtgctg aatttttaag cgaccatgaa
    48361 tctgaatatg gctattctat caaatatttt gatgctgctg atcaattgta cgacgggtta
    48421 aaagttggcg caatcgatgc aatgatggat gattatccgg taatcggtta tgcgatcaaa
    48481 caaggacaag aattggaaac accgatcaaa aaagaatctg gcggaaaata tgcatttgcc
    48541 gttaaaaaag gacaaaatcc tgagcttctt aatatgttca atgaaggatt gaaagaatta
    48601 aaaagaacag gcgaatacga taagattatt aaagaatatg tagcggatgg ttcagaaact
    48661 tccagtgagt cttccactgc tgatgaatca acatttcttg gacttatcca aaacaactat
    48721 caagcattgt tgaaaggact ttggagaaca attctcctaa ctttgatctc ctttgctttg
    48781 gctatagtaa tcggtgtgat ttttggatta ttcagtgtag caccaatacg cgctcttcgc
    48841 acaattgcta gtatttatgt cgatatcatc cgaggaattc caatgatggt tcttgcgttc
    48901 tttattttct ttgggttgcc tggtatcgtt ggatttacga ttcctgactt ccttgctggt
    48961 gttatcacct tgactcttaa cgcaagtgct tatatcgcag agattgttcg aggcgggatc
    49021 aacgccgttc ctgtcggaca aatggaagct tccagaagtt taggtctttc ttataatcgg
    49081 acaatgcaaa aaatcatttt gccgcaagcg atacgcatca tgatcccatc attcgtcaat
    49141 cagttcgtta tctcattaaa agacacaacg atcatttccg caatcggtgt agtcgaattg
    49201 ctgcaaactg gtaagatcat tgttgcacgt acaacacaaa gtacgtatgt ttacttgatc
    49261 attgcgatca tgtacttgat tttgatcaca gcattgacaa aattagcaaa agttttagaa
    49321 aagaaggtga agtaagatgg cagaaaaaat cttagttgag catttagtca aaaaatacgg
    49381 cgataacaca gtattaaacg acatcaatgt gtccatcaac gaaggagatg tcgtctgtat
    49441 cattggccct tcaggttcag gaaaaagtac atttttgcgt tgcttgaatc gtttagaaga
    49501 accttctgac ggtgaaatta ttattgacgg cgcccacttg atggataaaa gcacagatat
    49561 caacttggtg agacaacata tcggaatggt attccagcac tttaacctat tccctcatct
    49621 ttctattttg gaaaacatca ttttagcacc gatggacctg aagaaagaat ctagagaaga
    49681 agcagagaaa aaagcaatca aattgctgca gacagttggt ctagaagata aaaaagatat
    49741 gtatcctgaa atgctttccg gtggacaaaa gcagcgtgtg gctattgctc gtgctctagc
    49801 gatgaaccct gacatcatgc tttttgatga gcctacatct gcactcgacc ccgaaatggt
    49861 cggtgatgtc ttgaacgtca tgaaaaagtt agcagaacaa ggtatgacga tggttatcgt
    49921 tacgcacgaa atgggcttcg ctaaagaagt ggccaatcgt gtcatgttca ttgacgacgg
    49981 aaacttttta gaagacggaa cgcctcaaca aatctttgaa aatccgcaaa atgaacggac
    50041 aaaagatttc ttgaataaag tattaaatat ttaataaaaa ccaaaaatgc ccggtcgctt
    50101 catgacgacc gggcattttt agtttcttgt tttttcactt aactgtacca gccgcatcgc
    50161 ttgttctcct gcacaaacaa gcaatcgctc tacctgttcc atcgcataag aaagtaccat
    50221 cggttcattg acgatatcaa gtacatagtc gataccacct tcagaaacta tgatgattat
    50281 cttattctaa agctggcttt tttgttggta caaacatgac aactacaaaa aaaccaggcg
    50341 aacgtatgat tgttcgtctg gtttttaatt attaatgact tagcgttttt actagaaata
    50401 gaaaatttgg gcaagtctac tttatatttt tactagaaaa actacttccg ctttttcccg
    50461 ccaaaagcat ctttaaactt atcgaagaaa ccgtcttctt gctgttcttc aactttgatg
    50521 ccgccagctt cagcgaatgc acgtaatgct tctctttgtt gttcatttag atttttcggt
    50581 gtgatcagtt ttactttgac atgttggtcg cctgttgcac caccacgtaa cttcggagcg
    50641 ccttttccac gtaaacggaa gttcgtacct gtctgtgttc cagcagggat cttcaatttc
    50701 acatctccat ggacagttgg tacttggact tcatccccca aagctgcttg tacaaaactt
    50761 aaaggcaatt catagtaaat ttcagaacct tcacgatcaa agatatcact ttcttctaca
    50821 cgaaaaacca catacaaatc accaaatggt ccgccgtttt ctccagcttc tccttgacca
    50881 gctaaacgca tttgttgtcc ttcttctaca ccagctggta cattcacttt aactgaatgt
    50941 gctttcttct catgtcctga gccatgacag gttggacaag gttctttgat ttctttccct
    51001 gtgccatgac aaacatcaca agtttgacgg ctcatcactc gtccaagtgg cgtttggcgt
    51061 tctacattga tcgtacctgc accatgacat ttatgacaag tagttggttg tgtgcctggt
    51121 tttgcaccgt ttccaccaca agtatgacag atttcttccc gattatactt gatttctttt
    51181 tctacaccaa aaatcgcttc ttcaaaagac aagtcgaccg tatattgcaa atcagcacct
    51241 tgacgaggcg catttggatc gactgaccga ccgcctcctc caaagaaaga gtcgaagata
    51301 tcttcaaaac caccgaagcc gccaccagag aagccgccga atccaccaaa tccgccacca
    51361 gctccaccag caccgtaatt tggatctgtg cctgcatgcc cgtattggtc gtatgcagcg
    51421 cgtttttgcg ggtcacttaa aatctcatat gcttctgata cttctttgaa tttttcttcc
    51481 gcatcaggtt ctttattgat gtcaggatgg tattttttcg aaagcttacg ataagctttc
    51541 tttatttcat cttctgatgc tccttttgag agccctaaga cttcataata atcacgtttt
    51601 gttgccatag gctttcctcc tattggttct catcattttc acgtcgcttg ttatcatatc
    51661 atattttgtt tgaaacaaaa accgatactt caaactattt ttcaaaagaa aaagccaaag
    51721 tagcaacttt ggccttctct cgaaattcag tgaactgatt atttatcgtc gccatcgact
    51781 tcttcaaaat cagcatcaac gacatcatct gctccgcctt gagctgcttc tggattttct
    51841 tgagcttgtt gttgtgcagc ttgttcgtat agtttaacag tcaagttttg aacgatttcg
    51901 ttcaatgcat cgcgtttagt tttcatttcc tcgatgttgt ttgcttcaac agcggctttt
    51961 aattcgtcac gagctgtttc tgcttttttc acttcttctt cgtccacttt gccttctaat
    52021 tctttcaatg ttttgtccac agagaatagc aatgcgtcta catcattacg taggtcaact
    52081 tcctctttac gagctttatc tgcttcagcg tttgcttctg catctttcac catacgttcg
    52141 atttcttcgt ctgttagacc tgaagaagat ttgatcgtga ttttttgttc tttttgtgta
    52201 cctagatctt tcgcagatac atttacaatc ccgtttttat caatatcgaa tgttacttcg
    52261 atttgtggaa taccacgagg agctgctgga atatctgtca attggaatct tcctagagtt
    52321 ttgttgtcag cagccattgg gcgttcacct tgtaatacat ggatgtctac tgctggttga
    52381 ttatctgccg cagttgagaa tacttgtgat ttacttgttg gaatcgttgt attgcggtca
    52441 atcaatttag tgaacactcc acccattgtt tcgataccta atgacaatgg tgtaacgtca
    52501 agtaaaacaa catctttcac atcaccagtg atcacgccac cttggatagc agcacccata
    52561 gcaactactt catcagggtt aactgatttg tttggttctt ttcctgtttc tttacgtact
    52621 gcttctacaa ctgcagggat acgagtagat ccaccgacta aaataacttc gtcgatttct
    52681 gattgtgaca gacctgcatc ttttaacgct tgacgtactg gtacttttgt acgttctact
    52741 aagtcagctg ttaattcatc aaattttgca cgtgtcaatg tcatttccaa atgcaatggt
    52801 ccagattctc ctgctgtgat aaatggcaag ctgatttgtg tgcttgatac gccagataaa
    52861 tcttttttcg ctttttcagc agcgtctttc aagcgttgta aagccatttt gtcttgagac
    52921 aagtcaatgc tgttttcttt tttgaattct gctaccatgt agtcgatgat tttgttatca
    52981 aagtcgtccc cacctagatg gttgtcgcca gctgttgaca atacatcaaa gacaccgtct
    53041 cctagttcaa ggatagatac gtcaaaagta ccgccaccaa ggtcgaatac taagattttt
    53101 tcgtcgcgat ctgttttatc taaaccatag gcaagagcag ctgcagttgg ttcattgacg
    53161 atacgttcta cttctagacc agcgatctta ccagcatctt ttgttgcttg acgttgtgca
    53221 tcattaaagt aagctggcac agtgataact gctttttcga ctttttcacc taaatagtct
    53281 tctgcgaatc ctttgatata ttgaaggatc attgctgaga tttcttgtgg tgtatatgat
    53341 ttaccttcta catctacttt gtaacctgct tcaccgatat ggcgtttgat tgatgaaatc
    53401 gtatttgggt ttgtcacagc ttgacgtttt gcaacttccc ctacttggat ttctccattt
    53461 ttgaatgata caacagaagg tgttgtacgg tttccttctg ggttagcgat gatttttgct
    53521 tcgtttcctt ccaatactgc tactgcagag ttagtcgtac ctaagtcaat accgataatt
    53581 ttactcataa ttaacgtctc cttctttaat tgaaagtgta agttttatat ccgcacaatt
    53641 attgtgcaac aatgaccata gttggtctta acacgcgatc atgtaatttg tagccttctt
    53701 gtagtacttc tacaatcgta tcggctggtg tatcttcagt cgctggaaca gtttgtactg
    53761 cttgatgaag attaggatca aaggcttctc ctttagcagg gattttttca attccttctt
    53821 cttccagtgc gttacgcaaa ctttccaaga ccatttccac gccttttttc aaacctgccc
    53881 cttgatcatc tgacacttct gtggctaatg cacgttccag gttgtcaatt gatggaagta
    53941 attttttggc taaatcttgt gaacggtatt tttgtaattg ctcacgctca ttttttcctc
    54001 gatttgccat atttgcgatt tcagcacgag cccgcaagta tttatcttcc atttcttcta
    54061 actcagcttt taatttcgct gtttcgaatt cttccgcttc agcttctgaa atacccgaat
    54121 cttctgcagc ttcgacatcg atttccggtt ctggctgagc atctgtcatt tctttatcta
    54181 gttcttcttg attttctttc acgatacagt cttcctttca ttattcagtc agctgtttga
    54241 ttgctcttac taagaaagag agaacgatca gctgcaaata gcttcgttat tcacattacg
    54301 agtttgacaa gtcaagcgag cggtagtaat cagcaagttt agctgctagt tctcttcgat
    54361 aaacatcgac tagaccgaac atccgagaat aaggcatact agtaggccct aacaaggcta
    54421 ttgtacctct tccatgacca tctatctcgt aacttgcttg aatcatactc atattctgca
    54481 ataaatcatt gcctaattca gcaccaatct tgatatgaat attgctatcc atcggagtga
    54541 tcatttgtgt aagtccgtct gagtctttca taaaagaaaa catcgatttg aactgatcaa
    54601 gatcttgacg gggctcataa tccaagagat tcatttgtcc actgacataa accttttctt
    54661 caaaaacatg accaagaacg gtgtcaaata actgagacat cccttctgtc gtctggaaat
    54721 atttatgaag aatcatcgga atctccgtac gaagtttatg gtacaccgtc atcagaggat
    54781 ctccgactag acggtcgttt acaatctgta ccattttttc tagttcctga cttcccatat
    54841 attcgggaag agtgaacact tggctttcta cattccccat atctgttacg acgatagcaa
    54901 taatctgtcg attattcaag ggtacgatac gaaagccagt cagtcggcgg tcttttattt
    54961 caggtcccaa tgaaaaagtc gtatagcttg tcagctcaga taatatctca gcagattgct
    55021 taataatctc attgatttca tgaaattctc tgcctagaga ctgacgaatc agcagcaaat
    55081 catcttctgc tacgcgagca ggttttaaca aatgatccac gtaataacga tagcctaaag
    55141 cagatggaat ccgcccagaa gaagagtgag tcttcaacag caatccttca tcttctaatg
    55201 ctttcatatc attgcgaatc gttgctgagc tggccttgac tccctcagac attaatgttt
    55261 tggaaccaac gggcacgcca ctactcgtat agtgttggat gatcagacgt aaaatgtcgt
    55321 tttgtcgctt tgttaacatc ttcctcacct ctcattagca ctcatatatt ctaagtgcta
    55381 attcacttat aaatatagca agaagccctt ctcctgtcaa gagaaagact ccatttttta
    55441 gcactctaaa cacaagagtg ctaattctaa ataattgatg taaatccagt tatatcaata
    55501 cttcaatacc tcattgtcaa actttctaaa ctttttcttt tcaagtttcg ataaaaaaca
    55561 aatattcttc aaactatttt tcaaataaaa agcgctcaaa cacattgttc cccaaaaaag
    55621 tccctcttgg tgtcaaataa acacggtctt cttcattaac aagtaaccct tcttgctcta
    55681 attcccttag cacatcaccg tacaccgatt caattgtttt ttgatagcga tcatagaaat
    55741 gttttttagt aatccctgtt ttttttctta gtcctaagaa catttcttct tctatttgat
    55801 tttttcgtgt caatttttct tcttccaata ccgggcgttc atttgctcgt aatgggcgta
    55861 aatagtgttg gattggtcct ttgttgcggt aacgaatatc tccaagataa ccgctagcac
    55921 cagctccaaa cccaaaatag tggtcattgt tccagtacat gaggttatgt tgagattcat
    55981 gtccggagag cccaaagtta cttatttcat attggtgacg tccatgcttt tccattgctt
    56041 caatcgtctc ttcaaacatt ctggtttccg tttcctgatc aggcagttcg agtcttcctt
    56101 gtcgtaccca gttcatgaac attgttttgt tttcgaggat caatgagtac aaagaatagt
    56161 gaggcagatc caaagccaaa gctttttcca aagtatcccg atatccttct agtgtttgtc
    56221 ccggtaatgc ataaatcaaa tcgatgctta cattggtaaa attttctgct tctaaaaatt
    56281 gcattgtttg atacacatct tctgcagtat gtttacgtcc aatttttttc aataagcgat
    56341 tgtcaaatgt ctgcactccc atggataaac gattgacgcc atagtttttc atcacttgaa
    56401 gtttttcacg ggtcaaatca ccaggattcg cttctacagt aaactcatta ccattttgaa
    56461 aaggcaggat ctctctagca cctgataata gtcgatcaag ttgtttagca gataaagaag
    56521 ttggtgttcc gcctcctaca taaagtgttt ccaaattcgc tgtaggatga ctttccagca
    56581 ttaatctcat ttcattcagc agcatttcca catactcatc tactggctgc ccttctaaaa
    56641 aaactttatt aaagtcacag taatagcaga tatgctcgca aaatgggata tgaatgtacg
    56701 cagaaacctt gttttctgcg ggatttattg tttctatcat tgaaattctt tctccttacg
    56761 tcgaaaagtc gtgcctgttt tcgaccttct taaaatcgcg ttcaagcacc aactcattga
    56821 aataagccgc atatttagaa tcaaggaaac ctagctctaa aaatgcttgc ttattgtcat
    56881 cggagctaca cggtgctttt acagcctctc gataaacggt aatcgcaaag ctgaccttcg
    56941 gcattaagtc aaaatctgca aaaatatgaa aagctatttt cacagattcc tccttaagtg
    57001 ctcagaccac aacgctttgc ttacaacctc tcatatacgc atactaaacg tatttggcga
    57061 acaaatccac taaaaaatcc aagaatcgac ttcttggatg atttttttac actcatgatt
    57121 cttcctaaac aattttgtcc ttattttatt cataaaaaaa tctagtcaaa tctctcactt
    57181 caagagtttt aactagattc caattattat ttttttgtaa aaataaacag tctcttaatc
    57241 atagacattt cttcggtgcc ctacttgaat agcgataaca acgaattgat tatcttctat
    57301 ctctaccaat acacgtattt gccaatcaga gctgcttctg aatttcgggc gtgaatttta
    57361 aacggcaggt cattccagcc caccaaattc attaaggatt cttccatgaa tactgttgtt
    57421 ttcccacttc ttatccaatg tttatgggca atttcagccg tttgacgatt gtattcatct
    57481 tctagttgtt ccatcgaata gttttttaga agttcagata aagtaatccc ataaaattca
    57541 gccatataag aaagccattc ttttttggcg tcacttacac gaaccgtaat catagcccta
    57601 taattgcctc tcttaaagaa tctcatgcat ttcctgatgt gattttagaa aaatttactt
    57661 gctaaaaaac tgtgaaaatg taggagctag catccttgta gtaaatgatc gagctcttta
    57721 ttatacatta aaaaagttca gaaattttga tgaagtagcc aactactttt tcatgagtaa
    57781 agcaacacta gaaaaagaat cctccagtac ttagaattta ctggaggatg tacttttgaa
    57841 gaagcctata ggttatttaa aaaatattac tacaggaagg aacgagaatt acttcgttac
    57901 ttataataga acttagtctt atatagaagg catagctcac attagcttat ttgtcctata
    57961 aaaataaatt acggtatttt agaaaagcta ttttctcttt tttcaacgat cttcagcaat
    58021 ttttctttat cgtcaggtaa ctcaagttca tgaattctag catgacaatt gggacataac
    58081 gcgatacagt tttcaatcac atcttttcca ccttgcgaca aatattctat atgatgacaa
    58141 tgtaaataag gtacaccgtc ttttataaat ggcccttttt cttggcaaag ttgacaaata
    58201 ccttttgcaa gtcgtttaac atattcagat acgaagggat tacgtttata tatttttgtt
    58261 tttgagaagc aaaactcctc ttcgttaaca tattttgcag ccattttttt attataatta
    58321 ctaacttttc ttgcttcttc ctctaattta gcattagata aattacgaat atgtctagtt
    58381 tgattttctt cctggttata tatctttatc ttcaatcaat tgctcttgat ttattaaagc
    58441 taatggaaat ttatatactt ttctgctgtt gcccgaacta tctttttcat taacagtata
    58501 tatttgtcct gctaaatata cttctcccag atatgtgtgt tcttttggtt taaatgtttc
    58561 aaataaatga atctttacaa aattactttt tgaattggct aaaactttat tttgattctt
    58621 atccaatact tgatcccctt ttagccccat accggtatat tgtaaaatac catttaacca
    58681 cttatcttta taaacattac ttcctgtttg atcactaaac agtacaagag tattagtttg
    58741 atgagatctt ctcattccac cctgtttgga acatttaaac ttctctgaaa tttctttgtt
    58801 agtatatact ctaccaactt ctaactcacc taatatgttt ttagaccaat tttctcgcca
    58861 tgtaataatc ttatcaagat taaacatttc tccctctttt ggcatgccat ttctaattaa
    58921 attagctaat acaccagtag aaatatctaa tttttttagt aattctttct tagtaatcaa
    58981 tgttggattc ataacaatgc agctcctaat gatatcaata taattgcatt agataacttg
    59041 aaaaatcgaa aaaaactcat tttgtgtcaa gttatctgta atatataaaa atatcattat
    59101 tatacctcat ctatgtgaat ttttactatt cttaccttag catattcttt ataggtatat
    59161 cagagctaat caaactaaaa aatacccgaa gtcttcttat gtaaaaacac cggttattac
    59221 ttaaatatga cttaggtaaa acaatgagtg atccaattat aaaattttat ggcgaataat
    59281 ttagtaagcg ctacatattg aatgatttag aaattttgaa aaagtagcta gttcctttta
    59341 taccagaaaa gtaaacctaa taaaaaacac aactaatttt tagctgtgtt ttttaagtta
    59401 caataattat ctatttaata gtcttaattc attaaaataa aaaactcaac tttacaagga
    59461 tatggtttaa aaaatttatt tatccaaccc aactagtttt cgctgcttac gatttgcttc
    59521 atctgctacg taattcatta ctgttttaaa ttctttcgct gaggcgtttt ctgataaatc
    59581 agcgatactt ttattatact tcttcacgat ttgttgtact tgttctttct cagtcatgta
    59641 attcctcctc caactctttt gaagtatatt gtattggtag tactaattga atattatctg
    59701 ctgcataatg cacttcagaa atgtcgtttt gataatcctt aatcattatg tgaaggacta
    59761 cttcaggatg tctatttttg actttttcaa tattctctct ggacttaaaa aacgcattga
    59821 taaacatttc ttttggcaca tgacgtcctt cagctagttc acgttttcga gtgaaatccc
    59881 aggcaacttt gggatcttgg taaacataga aaatcgtaac gcgaaagtta tttttaaggg
    59941 ctcgaataat atttttctct gcactaagga tagcaaaagt atcctctagt atgaaagaat
    60001 agccatgttc cagtacatat tttaatgatt gttcaactaa ccaagaagaa gctttctgaa
    60061 aaacacttga gttctttcca ttgtattctg gaaattgtgc tctaaaatag tccgcatcaa
    60121 tcacaacatg gttgtcataa ttttaagcta aacctagtgc aacctctgtt ttacctgctc
    60181 ctgggcttcc agccatgaat accgcatctt tttcatcatc agggattttt cccttgatga
    60241 ttgtttcaat aaatttatct ttattgaccc tagcgtaatc taaatacttg tctttaggtt
    60301 ccaagattgc accttctttc cttcttctat attcatacta attatacgat atttatataa
    60361 aaaatataac ggtcatttta accatattaa catttagtca cagtaatagc agatatgctc
    60421 gcaaaatgag atatgaatgt acgcagaatc cttgttttct acggcattcg cttttttttc
    60481 attggactag ttatatattt ctagggttgt tttcatgtct gagtgcccga tatgatttat
    60541 ttttcgtttc tataattact ttttgccttc cagtttcttt taagattgta ctcaagcaag
    60601 tgggaattgg ttcttttgtc atccatgtat gcaaaatgtt ataatgctgg taaacaaaaa
    60661 tgattacctg tcatttttat ttagttcgta tttaattaag ttgactgtct gtatactctg
    60721 tctaaaactt aagaattgtt gttttcgctg tcgctatcca aatttaatga atgtctgtat
    60781 gttaaaactg ttgtccttgt catagatagt aaaggagagc ttgaaaatga aaactgcgat
    60841 tacgtttcta ttagaggaat atgccgattg ggaaggtgct tatattacta gcacactaaa
    60901 ccaaaaagag ggatggcaaa acaaaactgc ttctatccaa tcagaggtca cttccattgg
    60961 aggattaaaa acaaaaatcg attacttaat cgaacaaata cctgaaaaag ttgacctttt
    61021 tattatgatc ggtggcaatt catgggacat aaaaaatcat catttatatc aaataatcga
    61081 taaattgtta aaaacagacg taccagtagc tgctatttgt ggggcagttg attatttagc
    61141 tcagagcgga ttattgcaag gttacaaaca caccggaaat gcgcaatttc cttggttaga
    61201 atcggaaaat tatcagaata aagaagattt tatagaacaa caagctgtga aagatcgtaa
    61261 tttgattact gcgaatggaa cagctcctat agaattcaca gacttgattc ttcaagcagt
    61321 ccattttgaa acagaagaaa taagagaaaa aaagattcgt ctatacaaac ttggattcta
    61381 tgattactat aaaaagtacg gagatccttt ctcctaatca ttctcttcaa ttaaatactc
    61441 cttatcaata gtatgacaag taattttact gatggttatt tgtcacactt tttctgacat
    61501 ttatcaaaga agatacactc tatttatatt cata
//
LOCUS       DAZULR010000013        57516 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.013, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000013 DAZULR010000000
VERSION     DAZULR010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 57516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57516
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.013"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(61..2424)
                     /locus_tag="ACG8ZV_000914"
     CDS             complement(61..2424)
                     /locus_tag="ACG8ZV_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase"
                     /protein_id="HFS4996272.1"
                     /translation="MDYSSKEYFDKMTAWWRAANYLSVGQLYLKDNPLLRRTLKPEDV
                     KKHPIGHWGTIPGQNFIYVHLNRVINKYDLNMFYIEGPGHGGQVMVSNAYLDGSYTEI
                     YPEVTEDETGMQKLFKRFSFPGGIASHAAPETPGSIHEGGELGYSLSHAVGAVLDNPE
                     VISAVVIGDGEAETGPLAGSWFSNVFINPVIDGAVLPILHLNGAKIANPTILARKSDG
                     ELANYFNGLGWEPFFIEGNDPEKLNPVMAEKMDQAIEKIKSIQKEARLKTATDVVMPK
                     WPVLIVRTPKGWTGPKEWDGEPIEGTFRAHQVPIPVDQEHMDHADALLRWLKSYEPEK
                     LFDAQGRILEEIREIAPTGDQRMAKNPITNGGIDPRPLIMPDWKKYTLQFEKPGSVKA
                     EDMTELGKFVREIIEKNPENFRIFGPDETKSNRLNQVFKTTNRQWMEKIEPENDEWLS
                     PSGRVIDSQLSEHQDEGFLEGYVLTGRHGFFASYESFLRVVDSMLTQHFKWIRKSHDL
                     SWRKDYPSLNLIASSTVFQQDHNGYSHQDPGILTHLAEKKAEFIREYLPADANTLLAV
                     MDKAFRSSEKINLIISSKHPRAQFYSAEEAAVLVNEGLKIIDWASTAKEEEPELVIAA
                     AGTESNLEALAAVTLLLEEFPKLKIRFINVVDLLKLRHPSQDPRGLSDEEFDQYFTKD
                     KPILFAFHGYETLVRTIFFDRHNHHLMIHGYKENGDITTPFDMRVVNELDRYHLAKDA
                     ALKIKGSQAEDFAEKMDQKLQEHQNYIRENGIDLPEVLDWKWKNLDQ"
     gene            2589..3093
                     /locus_tag="ACG8ZV_000915"
                     /pseudo
     CDS             2589..3093
                     /locus_tag="ACG8ZV_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035543.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(3201..3548)
                     /gene="rbfA"
                     /locus_tag="ACG8ZV_000916"
     CDS             complement(3201..3548)
                     /gene="rbfA"
                     /locus_tag="ACG8ZV_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HFS4996273.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKKAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(3575..5881)
                     /gene="infB"
                     /locus_tag="ACG8ZV_000917"
     CDS             complement(3575..5881)
                     /gene="infB"
                     /locus_tag="ACG8ZV_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HFS4996274.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSSDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(5894..6205)
                     /locus_tag="ACG8ZV_000918"
     CDS             complement(5894..6205)
                     /locus_tag="ACG8ZV_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HFS4996275.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(6202..6495)
                     /locus_tag="ACG8ZV_000919"
     CDS             complement(6202..6495)
                     /locus_tag="ACG8ZV_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HFS4996276.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(6517..7692)
                     /gene="nusA"
                     /locus_tag="ACG8ZV_000920"
     CDS             complement(6517..7692)
                     /gene="nusA"
                     /locus_tag="ACG8ZV_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HFS4996277.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(7716..8189)
                     /gene="rimP"
                     /locus_tag="ACG8ZV_000921"
     CDS             complement(7716..8189)
                     /gene="rimP"
                     /locus_tag="ACG8ZV_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HFS4996278.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(8333..12685)
                     /locus_tag="ACG8ZV_000922"
     CDS             complement(8333..12685)
                     /locus_tag="ACG8ZV_000922"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HFS4996279.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIQ
                     LGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSFIV
                     KKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYAPE
                     GEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGKKA
                     GVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAVKM
                     YKGNVIESFDEFIDPGHPLSRTTVDLTGITDEMVRGSKSEEEVLRMFLEFSKDTILVA
                     HNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSLEQ
                     HHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILAKN
                     QAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKGVE
                     EARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVATGN
                     VHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEIVV
                     ENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRLEK
                     ELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAPHY
                     YCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPDID
                     LNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSAEV
                     DRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHSIH
                     DNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIYSK
                     TGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDATLA
                     EVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVPDW
                     YIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMCKG
                     KDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFVIE
                     GDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGVLK
                     DLPDENQLSLFDML"
     gene            complement(12897..14606)
                     /locus_tag="ACG8ZV_000923"
     CDS             complement(12897..14606)
                     /locus_tag="ACG8ZV_000923"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HFS4996280.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPKRDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            complement(14674..15942)
                     /gene="rseP"
                     /locus_tag="ACG8ZV_000924"
     CDS             complement(14674..15942)
                     /gene="rseP"
                     /locus_tag="ACG8ZV_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HFS4996281.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(16103..16903)
                     /locus_tag="ACG8ZV_000925"
     CDS             complement(16103..16903)
                     /locus_tag="ACG8ZV_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HFS4996282.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(16900..17712)
                     /locus_tag="ACG8ZV_000926"
     CDS             complement(16900..17712)
                     /locus_tag="ACG8ZV_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HFS4996283.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            complement(17907..18464)
                     /gene="frr"
                     /locus_tag="ACG8ZV_000927"
     CDS             complement(17907..18464)
                     /gene="frr"
                     /locus_tag="ACG8ZV_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HFS4996284.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(18467..19189)
                     /gene="pyrH"
                     /locus_tag="ACG8ZV_000928"
     CDS             complement(18467..19189)
                     /gene="pyrH"
                     /locus_tag="ACG8ZV_000928"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HFS4996285.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(19325..20206)
                     /gene="tsf"
                     /locus_tag="ACG8ZV_000929"
     CDS             complement(19325..20206)
                     /gene="tsf"
                     /locus_tag="ACG8ZV_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HFS4996286.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(20305..21087)
                     /gene="rpsB"
                     /locus_tag="ACG8ZV_000930"
     CDS             complement(20305..21087)
                     /gene="rpsB"
                     /locus_tag="ACG8ZV_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HFS4996287.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            21446..21925
                     /locus_tag="ACG8ZV_000931"
     CDS             21446..21925
                     /locus_tag="ACG8ZV_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFS4996288.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            22142..23233
                     /gene="phnW"
                     /locus_tag="ACG8ZV_000932"
     CDS             22142..23233
                     /gene="phnW"
                     /locus_tag="ACG8ZV_000932"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047304 - 2-aminoethylphosphonate-pyruvate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HFS4996289.1"
                     /translation="MYKLLTPGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSGSFGVESVLSSVIRPEDTVLICSNGAYGQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQEKDLL
                     FIVDAMSSFGGIPIRVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            23226..24011
                     /gene="phnX"
                     /locus_tag="ACG8ZV_000933"
     CDS             23226..24011
                     /gene="phnX"
                     /locus_tag="ACG8ZV_000933"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050194 - phosphonoacetaldehyde hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HFS4996290.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIREP
                     MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEHYLFKDLVKHSTLKP
                     DTLETIERLRNAGINIGSTTGFTAPMMTIVAETAKKEGYSPDFMATSEDVEGYGRPFP
                     YMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEGSSLMGISYDEYQKL
                     EMGKKDRLKQSVALRFQQAGADICVNNLKELTEYILYADKNPE"
     gene            complement(24357..26048)
                     /gene="argS"
                     /locus_tag="ACG8ZV_000934"
     CDS             complement(24357..26048)
                     /gene="argS"
                     /locus_tag="ACG8ZV_000934"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HFS4996291.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDEEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMRHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(26470..27417)
                     /gene="arcC"
                     /locus_tag="ACG8ZV_000935"
     CDS             complement(26470..27417)
                     /gene="arcC"
                     /locus_tag="ACG8ZV_000935"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HFS4996292.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(27532..28551)
                     /gene="argF"
                     /locus_tag="ACG8ZV_000936"
     CDS             complement(27532..28551)
                     /gene="argF"
                     /locus_tag="ACG8ZV_000936"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HFS4996293.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(28642..29871)
                     /gene="arcA"
                     /locus_tag="ACG8ZV_000937"
     CDS             complement(28642..29871)
                     /gene="arcA"
                     /locus_tag="ACG8ZV_000937"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016990 - arginine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0019546 - arginine deiminase pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HFS4996294.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            30332..31033
                     /locus_tag="ACG8ZV_000938"
     CDS             30332..31033
                     /locus_tag="ACG8ZV_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFS4996295.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(31605..32621)
                     /gene="tsaD"
                     /locus_tag="ACG8ZV_000939"
     CDS             complement(31605..32621)
                     /gene="tsaD"
                     /locus_tag="ACG8ZV_000939"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HFS4996296.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIVAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(32618..33082)
                     /gene="rimI"
                     /locus_tag="ACG8ZV_000940"
     CDS             complement(32618..33082)
                     /gene="rimI"
                     /locus_tag="ACG8ZV_000940"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HFS4996297.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLVEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(33089..33631)
                     /gene="rimI"
                     /locus_tag="ACG8ZV_000941"
     CDS             complement(33089..33631)
                     /gene="rimI"
                     /locus_tag="ACG8ZV_000941"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HFS4996298.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTIEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(33615..34337)
                     /gene="tsaB"
                     /locus_tag="ACG8ZV_000942"
     CDS             complement(33615..34337)
                     /gene="tsaB"
                     /locus_tag="ACG8ZV_000942"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HFS4996299.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDKIIVPMFDARRKNVYAGAYRWKENRLEIVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFYEIKEILPSAMINTVPAWDIPSGVTVAQLGALAEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(34528..35508)
                     /locus_tag="ACG8ZV_000943"
     CDS             complement(34528..35508)
                     /locus_tag="ACG8ZV_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFS4996300.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPTDGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(35532..37016)
                     /gene="galT"
                     /locus_tag="ACG8ZV_000944"
     CDS             complement(35532..37016)
                     /gene="galT"
                     /locus_tag="ACG8ZV_000944"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0017103 - UTP:galactose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019388 - galactose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HFS4996301.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLADYPQVIAGVVKWPMSVIRLQSTEKKLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(37028..38017)
                     /gene="galE"
                     /locus_tag="ACG8ZV_000945"
     CDS             complement(37028..38017)
                     /gene="galE"
                     /locus_tag="ACG8ZV_000945"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HFS4996302.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREVLGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            38266..38433
                     /locus_tag="ACG8ZV_000946"
     CDS             38266..38433
                     /locus_tag="ACG8ZV_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HFS4996303.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(38495..40306)
                     /locus_tag="ACG8ZV_000947"
     CDS             complement(38495..40306)
                     /locus_tag="ACG8ZV_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HFS4996304.1"
                     /translation="MKIGIIGAGPRGLSIAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNDLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSREGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGSMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLEIPLTYQDESFAEASRAFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPVIRTKELAALIDAGIFHLFEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(40303..40668)
                     /locus_tag="ACG8ZV_000948"
     CDS             complement(40303..40668)
                     /locus_tag="ACG8ZV_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HFS4996305.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(40831..41226)
                     /locus_tag="ACG8ZV_000949"
     CDS             complement(40831..41226)
                     /locus_tag="ACG8ZV_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFS4996306.1"
                     /translation="MVLWVINIILLLIVLAIIFWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(41244..42206)
                     /locus_tag="ACG8ZV_000950"
     CDS             complement(41244..42206)
                     /locus_tag="ACG8ZV_000950"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HFS4996307.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRYLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACANLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(42206..42418)
                     /locus_tag="ACG8ZV_000951"
     CDS             complement(42206..42418)
                     /locus_tag="ACG8ZV_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HFS4996308.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(42439..43137)
                     /locus_tag="ACG8ZV_000952"
     CDS             complement(42439..43137)
                     /locus_tag="ACG8ZV_000952"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HFS4996309.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(43157..43699)
                     /locus_tag="ACG8ZV_000953"
     CDS             complement(43157..43699)
                     /locus_tag="ACG8ZV_000953"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HFS4996310.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(43831..44835)
                     /locus_tag="ACG8ZV_000954"
     CDS             complement(43831..44835)
                     /locus_tag="ACG8ZV_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFS4996311.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIGLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(44832..45821)
                     /locus_tag="ACG8ZV_000955"
     CDS             complement(44832..45821)
                     /locus_tag="ACG8ZV_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFS4996312.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(45818..46624)
                     /locus_tag="ACG8ZV_000956"
     CDS             complement(45818..46624)
                     /locus_tag="ACG8ZV_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4996313.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKITLLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            46790..47746
                     /locus_tag="ACG8ZV_000957"
     CDS             46790..47746
                     /locus_tag="ACG8ZV_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFS4996314.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(47823..48341)
                     /locus_tag="ACG8ZV_000958"
     CDS             complement(47823..48341)
                     /locus_tag="ACG8ZV_000958"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0005542 - folic acid binding [Evidence
                     IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HFS4996315.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(48429..48578)
                     /gene="rpmG"
                     /locus_tag="ACG8ZV_000959"
     CDS             complement(48429..48578)
                     /gene="rpmG"
                     /locus_tag="ACG8ZV_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFS4996316.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            48806..49252
                     /locus_tag="ACG8ZV_000960"
     CDS             48806..49252
                     /locus_tag="ACG8ZV_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HFS4996317.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(49447..51342)
                     /gene="asnB"
                     /locus_tag="ACG8ZV_000961"
     CDS             complement(49447..51342)
                     /gene="asnB"
                     /locus_tag="ACG8ZV_000961"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HFS4996318.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKLDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(51667..52641)
                     /gene="bsh"
                     /locus_tag="ACG8ZV_000962"
     CDS             complement(51667..52641)
                     /gene="bsh"
                     /locus_tag="ACG8ZV_000962"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HFS4996319.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGEGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNINKEDLDRHELVSYPVIKEQQINYVN"
     gene            complement(52977..53064)
                     /locus_tag="ACG8ZV_000963"
     tRNA            complement(52977..53064)
                     /locus_tag="ACG8ZV_000963"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(53030..53032),aa:Ser,seq:cga)
     gene            complement(53209..53775)
                     /locus_tag="ACG8ZV_000964"
     CDS             complement(53209..53775)
                     /locus_tag="ACG8ZV_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFS4996320.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            54030..55361
                     /locus_tag="ACG8ZV_000965"
     CDS             54030..55361
                     /locus_tag="ACG8ZV_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HFS4996321.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGVFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSVLSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGILLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLSGIREIFDSSGKLTT
                     DFIANSGIGATLINMGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSASGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            55327..55677
                     /locus_tag="ACG8ZV_000966"
     CDS             55327..55677
                     /locus_tag="ACG8ZV_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996322.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(55769..56188)
                     /locus_tag="ACG8ZV_000967"
     CDS             complement(55769..56188)
                     /locus_tag="ACG8ZV_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HFS4996323.1"
                     /translation="MMTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVTFEPGCRNHWHVHTDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(56189..56533)
                     /locus_tag="ACG8ZV_000968"
     CDS             complement(56189..56533)
                     /locus_tag="ACG8ZV_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HFS4996324.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVEWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            56883..57479
                     /locus_tag="ACG8ZV_000969"
     CDS             56883..57479
                     /locus_tag="ACG8ZV_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFS4996325.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT        16181 a        12117 c        10052 g        19166 t
ORIGIN      
        1 cttaatttga caaataatac aatgtaaaaa attctgtttt gcgggatcga ttttatcatt
       61 ttattggtca agatttttcc atttccaatc caatacttct ggcagatcaa taccattttc
      121 acgaatatag ttttgatgtt cttgtaattt ctgatccatt ttttccgcaa aatcttctgc
      181 ttgacttcct ttgattttta aagctgcgtc ttttgccaaa tgataacgat caagttcatt
      241 tactacacgc atgtcaaatg gtgtcgtgat atctccattt tctttgtagc catgaatcat
      301 taaatgatgg ttatgacgat caaagaaaat cgtgcggacc aatgtttcat aaccgtggaa
      361 agcaaataag atcggtttgt cttttgtaaa atattgatca aattcttcat cgctcaaccc
      421 acgcggatct tgacttggat gacgtaattt caataaatct acgacattga tgaaccgaat
      481 ttttagtttt gggaattctt ccagcagcaa agttacagct gctaatgctt ctaagttaga
      541 ttccgttcct gcagcagcaa tgaccaattc aggttcctcc tcttttgctg tcgaagccca
      601 atcaatgatt ttcaagcctt cattcactaa gacggctgct tcttctgctg agtaaaattg
      661 agcacgcgga tgtttggaag agatgatcaa attgattttt tctgacgagc ggaatgcttt
      721 atccatgact gcgagcaatg tatttgcatc cgcaggcaga tattcacgga tgaactccgc
      781 cttcttttct gccaaatgtg tcaatattcc tggatcttgg tggctatatc cattgtgatc
      841 ttgctggaag actgttgagc ttgcaatgag attcagcgaa ggataatctt ttcgccaaga
      901 aaggtcatgt gatttccgta tccatttgaa gtgctgagtc aacatagagt caaccactcg
      961 caagaatgat tcgtaacttg caaaaaaacc atgccgtcca gtcagaacgt acccttctaa
     1021 gaacccttca tcttggtgtt ccgataattg actgtcgatg acgcgaccag atggcgaaag
     1081 ccattcatca ttttctggtt cgattttttc catccattgg cgatttgtcg ttttgaaaac
     1141 ttgattcaat cggtttgatt ttgtttcatc tggtccaaat atacggaaat tttctggatt
     1201 tttctcaatg atctcgcgaa cgaatttacc aagttcggtc atatcttctg ctttaacgga
     1261 gcctggtttt tcaaattgca aagtatattt tttccaatct ggcataataa gcggtcttgg
     1321 atcgattcca ccattggtga taggattttt tgccattctt tggtcaccag taggcgcaat
     1381 ttctctgatt tcttctaaaa tacgtccttg tgcatcaaat aatttttctg gttcatagga
     1441 tttcagccaa cggagtaaag catctgcatg atccatatgt tcttgatcta caggaatcgg
     1501 tacttggtgt gctcggaagg ttccttcaat tggttccccg tcccattctt ttggaccggt
     1561 ccatcctttt ggtgtgcgta cgatcaatac tggccatttt ggcatcacga catctgttgc
     1621 tgtcttcagg cgagcttctt tttggatgga tttgattttc tcgattgctt gatccatttt
     1681 ttcagccata acaggattta atttttctgg atcatttcct tcaataaaga aaggctccca
     1741 gccaagtccg ttaaagtaat ttgctaattc tccatctgat ttacgtgcca agatcgttgg
     1801 gttggctatt tttgcaccat ttaaatgaag gatcggtaaa acagctccat ctatcactgg
     1861 attgataaag acatttgaga accagcttcc agctaaagga ccggtttctg cttcaccatc
     1921 accaatcacg acagcagaga ttacttcagg attgtctaat acagctccga ctgcatgtga
     1981 aagagagtat ccaagctctc cgccttcatg gatagaacct ggtgtttctg gtgctgcatg
     2041 agaagcaatg cctccaggaa atgaaaatcg cttgaataat ttttgcattc ctgtctcatc
     2101 ttccgttact tctggataga tctctgtgta acttccatct aaataagcat tcgataccat
     2161 gacttgtccg ccgtgtcctg gcccttcgat ataaaacatg ttcaaatcat atttattgat
     2221 gactcggttc aaatggacat aaataaaatt ttggccagga atcgttcccc aatgaccgat
     2281 tggatgtttt ttgacatctt ctggtttcag tgtacgtctc agtaaggggt tatctttaag
     2341 ataaagttgc ccaacagaaa gataattagc agcacgccac caagccgtca ttttatcaaa
     2401 gtattcttta ctagaataat ccatacataa cactcctttt cattattact cttattctag
     2461 cgcagatact cccaattgaa acctaataag cacttctgtt catttgtttg gattttatat
     2521 ctagccaaat gaacaggtat aaaaaaccac gaaatttttc ctttcgctga cgttttttac
     2581 attgatccaa aaaacttgtc gttatcacaa tggctgttcc gcagttcatt tcgctcctca
     2641 tcatgcataa tttgctgaat gacgctaggc cagttaacac attgttggaa aactggggct
     2701 ggatcgagca attcctttcc tgattgatcc gttttatgta aaagtctctg ttatctttgt
     2761 caatatgtga attggtatcc cagctactat gctaatttct acagggatta tccaaaattt
     2821 ggatcgtgac caaatcgaag cggcgtaatc ggaaatatca ataacttcaa cgtgattttt
     2881 cttttaactg tcaacggacc gacaaactca aacttttatg gtgcaggttc cactgatctt
     2941 ctagttactt ggctatacct gactgtcact aaaatagatt acaatctagc ttccgttatc
     3001 ggtatcttga tctttatcta tatgcaaaaa tttatatact atagaaaaaa gaaagtcgaa
     3061 ttttttactt ttctttttct cttttttggt tagctgacac gctaccagac taaagtcatg
     3121 gaactcttag gtaatacgtc ttaatgaaaa caaaaaaatc ccgcaacccc tgatttcaca
     3181 ggatttgcgg gattttttga ttagtctttg ttcaagtcgc gaagcaattc atcgatatgg
     3241 ttcccataga caactgattc atcaagttca aagaacaatt caggtgtctt ataaatactt
     3301 agattgtgcc ctaactctcg acgaatcaat cctgatgctt tattcaatcc atcttgtgct
     3361 tttttcttat ctgatgctaa gtcagataaa atgctgtaat agatcgttgc ttgctgtaag
     3421 tcccccgtaa ctttcacatc tgtgatcgtt acgttctcca cacgagggtc acggaccttt
     3481 ttgcgcaaaa tatcattgac ttcttttaag atttcttgac cgactcggcg atcacggtag
     3541 ttagccataa tgattggcct ccttttatca gtttttagtc atttttgact tcttccatga
     3601 taaatccttc aattacgtca tctactttga tgtcattgaa tttttcaatc atcgcaccac
     3661 attcataacc cattttgact tctttcacgt catctttgaa tcgtttcaga cttgcaagtt
     3721 ggccttcata gattacgatt ccgtcacgga ttacacggac accgctatct ctacgaatat
     3781 atccttctgt tacataggca cctgcaatcg taccaacttt agaaactttg aaggtttcac
     3841 gaacgatcat ttgaccggtg attttttctt caaattcagg gtctagcatc cctttcatcg
     3901 cagtttcgat ttcttcgatg gctttataga tgatacggtg aagacgaata tcgacttctt
     3961 cagtatcagc ttgcactttt gcctgcggtg taggacgaac gttgaaaccg atgataatag
     4021 cgttgctggc tgctgctaag gttacatcac tttcattgat tgctccgaca gctgaatgga
     4081 cgatttttac acggacacct tccacatcaa tcttcttcaa tgatgcagcc agtgcttctg
     4141 ctgaaccttg tacatctgct ttgatgatta cgttaacttc tttcaattcg ccttctttca
     4201 ggctttcaaa taagttgtcc aaagtcacac ggcttgtggc agcacggttt tccaataatg
     4261 cacgttttgc gcgttcttca cccgctgcac gtgctgtctt ttcgtcttcg aagactacga
     4321 aacggtcacc tgcttgaggt acatcattca agccagtgat ttctactggc gttgcaggtc
     4381 ctgcttcttt atcgcgacgg ccaagatcgt ttgtcattac acggacacgt ccgtaagtat
     4441 taccgacaac gattgggtca ccaacgtgaa gtgttccttc ttggacaagt aaggttgaca
     4501 caggaccttt acctttatca agacgtgctt cgatcactgt tccgattgcg cgttgtgttg
     4561 gatctgcttt taaatcttct acttctgcga ctaacaggat catttccagc aattcttcga
     4621 tgttttggcc gaatttcgct gagatctcaa caaaaatcgt ttctccaccc catgcttcag
     4681 gaattaattc atactcactt aattcttgca taacatgctg aggatttgca cctggtttat
     4741 caattttatt tacagcgacg atgattggaa cgcctgcagc tttggcatgg ttgattgctt
     4801 caactgtttg tggcatgacg ccatcatctg cagcaacaac taagatcgtg atatctgtga
     4861 tacttgctcc acgtgcacgc atacttgtaa aggccgcatg tcctggtgta tccaagaaag
     4921 tgattggttt accatcaata tcgatctggt aggcaccgat atgctgtgtg attccgccgg
     4981 cttcgccgct tgttacacgt gaatggcgca atgtatccaa taaggttgtt ttcccgtggt
     5041 ctacgtgtcc cataatcgtt actactggcg gacgtgagac taatttatct ggatcgactt
     5101 cttctgcctc gaagaattta tcgatatcag caatgtcaac ttggactttt tcttgtggtt
     5161 ccatgccata gtccgtcgct aacagttcaa tcgtatcttt atccagtgct tggttttgat
     5221 tgaccatgac accaagcata aataattttt taatgatttc tgctggctca cgatgaattt
     5281 ttttcgcaat atctgctacg ttcatacctt cagtatactc taatacatct ggcaattcac
     5341 ggaatttgcg tggtggtaca gctggtttag ttgattgttg ctgtttgcct tttttacctt
     5401 ttttattata acgattacgg ttattattat taaatttgcc gcgattgtta ttgtttggtt
     5461 tgttgttatt gttagtacgg ttttgattgc cgccttggct cgttccttga cgattttggc
     5521 tgctggtatt tcccgtatta ttttggtttg ttgttggttt ttttccttga ttcacttgac
     5581 cgctcccttg accgcgatct tgataactgc ggttattttt atttttttgt tgattgttcg
     5641 ttgtttcttt tttacgttga tcgttcggct gttgattggc tggttttctg cttgcttgtt
     5701 gtgcagcttg ttgtttcgtg cttgggtttt tgaacgcttg ttgcaatttc ttctcatcac
     5761 tgctagtaat cgcacccata tggtttttca catcgatgcc aagttgttgt gctttttcca
     5821 cgacgtcttt actagatttt ttgagttctt ttgctaattc atagattctt ttgttgccca
     5881 tgcaatcacc ttcctaacct tcaattagct ccttggtctt cttcgcaaat ccggcatcca
     5941 ttattccgaa taccttgcga ggttttccga tcatctgcgt gatttctgct tcagaaaata
     6001 gctcaaagca aggaacttca taatatgaac tcttatcttt tatctttttt cttgtattct
     6061 cacttgcatc ggttgccaca aacaccaatt ttgctttttg tttgcggatt tcagcaatgg
     6121 tcagttcttc acccgtgatt agttttcccg cgcgcatcgc tagaccgatg agattcatgg
     6181 ctttttgccg attaactgta ttcattttcc aaataactct ttacgtgctt tttggtgagt
     6241 gacatagtca agaagttctt gataaaactc atctgttaat gttgtttcga gtactcgatc
     6301 gagaattttt ttatcccaag cttgttgtac ttcttccggc tcaagtgaga catacgctcc
     6361 tcgtccaggc atttttccag ttggatcgat cgatacttcc ccttcttttg aacgggtgat
     6421 tcggaccatc tcttttttag gtttcatttc acctgaaacc acggatttgc gtaaaggaat
     6481 tttcctttgt ttcatctctt tgcctcctta ctaaagttaa gcttctggtt tttcttcgac
     6541 cgtttcattg ttgaatgcaa ttgtttcata ttcatcgtct gttaaatctg actgaacgat
     6601 tgcttcatca tgcagttctt ctgtttcttt ttgttgttct tgattttcat aaaattccgt
     6661 catgtcagat tctgatttga tatcgatttt atggttagtc aatttagcag ctaaacgtgc
     6721 attttgtccg cgtttaccga ttgctagcga taattggtag tctggaacga caactgtgca
     6781 ggcctttgga tttgtctcat cgaagatcac atccatgact tgtgcaggat tcaatgcatt
     6841 tgcgatgaat acagctggat cttcattcca ttcgacgata tccatgtttt cgccttttaa
     6901 ttcattgacg attgcttgaa ctcgttgtcc ctttggcccg acacatgtac cgactgcatc
     6961 gatatttgga tcatttgagc gaactgccac ttttgaacga tcgccagctt cacgggcgat
     7021 gctgacaatt tcaacgattc catcatagac ttctggtact tcttgttcaa ataagcgacg
     7081 caataggtct ggatggctgc ggctaacaaa tacttgcgga cctttagacg tattttctac
     7141 tcgggaaaca taaactttga ttcgatcatg tggttgataa aattcatttg gcatttgatc
     7201 ttgtttagaa agaactgcct caattttacc aagattgaca taaatataac gtttatcctg
     7261 gcgttcgacg attccttgca tgatgtcttt ttcataagca ctgaattcgt tataaataat
     7321 cgttctttct gcttcacgta cacgctgtaa aataacttgt ttagccgttt gcgcagcgat
     7381 ccgtccaaaa tcttttggtg ttacttcaaa acggatcgta tcaccgatct catatgctgg
     7441 attgattaaa agtgcatctt tcaatgagac ttccaactgt gaatccatca cttcttccgt
     7501 tacttctttt accgcataga catggatctt tccttttttc tgatcaaatt ccacttcgac
     7561 gttttgtgct tggccatagt gacgtttgta tgcagaaacc aatgctgctt ctaaagcatc
     7621 gatcacgatt tcttttgaga tccctttttc agcttctaaa gcgtctaacg catttaacat
     7681 ttctttactc atttttttct gattcctctc cgtgattaaa attggatagc taagcgagct
     7741 tttgcaatat tttttcggtc aaaagtcaat tctttttctc gtgtttttat gcgtattttc
     7801 aatgtaagct gttcagcatc aaatgattga agaaatcctt catattgttt ttcgccatct
     7861 actggttggt ataaggagac atggacataa tcaccaagtg ccttttcata gtcgctttct
     7921 tttttcaatg gccgctctgc tcccggggag gatacctcca ggaaataagc ttgaggaatc
     7981 ggatctggat ctgctgcatc aagtttttca ctcagtttct cactgacaaa ggcgcattct
     8041 tcgatatcga taccgccttc tttgtcaata aatactcgta agaaccagct ttttccttct
     8101 tttacaaatt cgacttcgac aagttcaaaa ttttgttcat ctaaaatcgg tgtcaccatt
     8161 tctgtgactg tttcaacgac gctactcaaa agtttcgcct ccttaaaaat taagtgcgta
     8221 attccattaa aaagagtgag cgaaaaatcc gctcactcac agttagtatc attacctata
     8281 agaactatac catactctgc ttaaaattac aagcagacag gaaaacagat gcttatagca
     8341 tatcgaataa cgataattga ttttcatctg gtagatcttt caatacgcca ttgtcgttca
     8401 tatattcgat caatgttttt gaaactttac cgcgggtggc aagatcttct ttggataaaa
     8461 atggaccgtc ttttcttgct tcaacgattt gtttcgccac gttggttccc aaacttggga
     8521 cagctctaaa tggtgcgatc aacgtatcac cttcaataac aaagttaacg gcatccgatt
     8581 tatacaaatc aatcattcca aatttgaatc ctcgttccag catttcattg gctaactcca
     8641 gcactgtcag ttgattcttt tcttttacgg aagcatctaa tcccttgtcc gtgatttctt
     8701 tcattgcttg tttcacagca tcttttcctt tgcacatgga gactagatca aagtcgtctg
     8761 cacgtacaga aaagtatgca cagtaataca aaatagggaa ataaaccttg aaataagcga
     8821 cacgaagagc catcaatacg taagctgcag catgggcttt cggaaacata tatttgattt
     8881 ttgaacaaga atcgatatac cagtcgggca cattattttc tttcatcgcc gatagatagg
     8941 tttctcgcaa ttcatcaggg atcttgttcc attgtccttt acgaacagtt tccatgattt
     9001 taaatgccat cccgctatct aatccagcat ggatcaaata aaccataata tcatcacgac
     9061 agccgattac ttccgccagt gtcgcatctc ctcgtcgaat caattcttcc gcatttccta
     9121 accatacgtc tgtaccatga gatagtccgg aaatttgcag tagttctgca aaagttgtag
     9181 gatgcgtttc ttctaacatc cctcgaacaa aacgagtgcc gaattctgga atacctaatg
     9241 tccctgtttt ggaataaatt tgttcctgac ttactccaag tacttcagga ccggcaaata
     9301 tccgcatcac ttccgggtca tccgtaggga tcgtttgtgg gtcgatccct gataaatctt
     9361 gaagcatccg aataacagtt gggtcatcat gccctagaat atctaatttc aatacattat
     9421 cgtgaatcga gtggaaatca aaatgagtcg ttttccattc tgaattttga tcgtctgctg
     9481 gatattggat cggcgtaaaa tcatagacat ccatataatc gggaataacg atgatccccc
     9541 ctggatgctg gccggttgtc cgtttgactc cagtagcgcc ttttgctaat ctgtcgactt
     9601 ctgcacttcg aaactgcaga ttattgtccc tttcgtatcc ttttacatag ccatatgctg
     9661 ttttgtcggc gactgtacca atcgttccgg cacggtaaac atagtcttcg ccaaacaata
     9721 ctttcgtata gttatgggct tctgcttgat aatcacctga gaagttcaaa tcaatatcgg
     9781 gcactttgtc tccatggaat cctaaaaatg tctcaaatgg aatatcatga ccgtctttgt
     9841 ttaagcgtgc accacatttt ggacattgtt tttctggcat gtcaaatcca gaaccatacg
     9901 taccatcttc aaaaaactcg gaatattggc actctggaca ataataatga ggggctaatg
     9961 gattaacttc agtgattcct gtcatcgtcg caacaaagct agagccaaca gagccacgtg
    10021 aacctactag atagccatct tcattacttt tatgcactag tttttgggcg atcagataaa
    10081 taaccgagaa gccattacca ttaatagaat tcaactcttt ttctaatcgt ttttgaatga
    10141 tctcaggtaa cggatctccg tacatttgtt ttgcttttgt gtaactcaat tctgatattt
    10201 catcttctga acctggaatc ttcggtgtat aaagttcatc tttgactgga atcacttctt
    10261 cgcagatatc tgcgatttta ttcgtatttt ctactacgat ctctttcgct gtttcttccc
    10321 ctaaaaagtg aaatgcagtt agcatctcat cggttgttcg gaaatggaca tccggcaaac
    10381 tatgacgatt caacggattc gctccgccca tagaattgat caaaattttt cggtaaatgg
    10441 catcttcttc gttcagataa tgtacattac ctgttgcaac aacgatttta tccaaacttt
    10501 ttccgatttc taccaaattt tggataattt cttccaaatc atgttcattt tttaccaatt
    10561 cttgctcgat caaaggcgca tagaccgctt ttggcataac ttcaatataa tcatagaatt
    10621 ttgctcggtt tcttgcctct tctacccctt tttgcatcat ggcttcgaat atttctccct
    10681 tatcacaagc tgagccgatc aatagatttt cacgcatctt tttcaattgg gagcgtggta
    10741 ttcgtgggac gcgttcgaag tattcgacat tcgacattga aatcagtttg aacaaatctt
    10801 tcagtcctgc ctgatttttt gctaaaatcg ttacatggaa aggtcgagcc cttttgtaag
    10861 aatctccttc tccgatatgc tcatttagct gatcatgata aagcatgtta tgattgtcca
    10921 ttgcctcttt cacaaagatc catgctaagt gaccagttgc ttcagcatca tagattgctc
    10981 ggtgatgctg ttccaagcta acaccaaact ttttagataa cacacctaat ccgaaacgtt
    11041 tgaattgagg atacagatat ctagctaatt ccaacgtatc aatgactgga ttggccgctt
    11101 caggaatacc ataccttgcg tagctagtat tcaagaaccc catatcaaaa gccgcgttgt
    11161 gggctaccaa aattgtatct tttgaaaatt caaggaacat ccgcaatact tcttcttccg
    11221 actttgaccc tcgaaccatt tcatccgtga taccagtcag atctaccgtt gttcgtgaca
    11281 atggatgtcc tggatcgata aattcatcaa agctttcgat cacatttcct ttatacattt
    11341 tgactgcggc tagctcgatg atcgtgtcat atactgcaga caatcctgtc gtttccacgt
    11401 caaatacgac gtatgtggct tcactcaatg cttcatgtgc atcattataa gcaattggga
    11461 caccatcatc tacgacattc gcttccacgc cgtataagat tttcacacct gctttttttc
    11521 cagcactatg tgcttccgga aaggcttgcg caccaccatg gtctgtaatg gcgatagctc
    11581 ggtgtcccca ttttcctgct tgtgccacaa gatcagagat gctgtttgtt gcatccatcg
    11641 tactcatatt gctatgaaca tgaagctcta ctcgtttttc cccttcagga gcataatctt
    11701 tgcgaggtgt atgtttgact tctatgatat cttgcgcatt catgaccaaa tcacggacaa
    11761 acgtatcttc ttgaatactt cctcgtacct ttaaccagct accgacactg atcgcatcaa
    11821 atacttgttc atctttttcg ccgttcgaga attttttgac gataaatgat gaagtataat
    11881 ctgtgatttt caaagtcaag atcttgcgtt ttgaacgtag ttctctgact tctttgtcga
    11941 atacgtaccc ctcaagtgtg actcttcgtt cttcttcaac gatactgatc attggtgtcg
    12001 ttggttcatc ggctggaata tttcgtccta gctggatggg tccttcaaga gctggcgatt
    12061 gctcttttct ttcctttttc ttttgttcgt ggacaactag actttcagct gcttgcttca
    12121 taaaggcttc tgcctgttct tgtttgcgtt cttcaaaaag tttcaataca cgttccgctt
    12181 gctgctcatc cacttctggt tcgatacgaa attttgggaa tccgtaactg acgaacaact
    12241 cttctactaa tggcaagtat tgttgcttca aataagaaat agctcctgta ctgtcgattg
    12301 gcaagatgac tttacgatct tttatcacag gtacctgcgt tttcaatact tgctgtgcta
    12361 gtggtgtatc gcattgctga ttttccaaag cttgggccca gtaatcttgc aagagctgtt
    12421 catcgaatgt ctggtcatct gctaagatat tcagtttgac ttgtgcaata tctttaaaag
    12481 cgatagtcag atgctgagtc aatgaccgat atagcataat aggcaaaatt ttggaaaaat
    12541 gtagcgtaaa ttcccataaa cgcgatttac gatggaccac tacactatcc atttcaccag
    12601 cagtaagcag tggatgattt ttttctgctt cctctagttg gatttgttcc aacagttttt
    12661 caaataaatc tcgtttttct gacaaagata tacgcccttt ctgatgagaa acaatgcaat
    12721 tgatcgcatc ttatcctctt ctttttcagt accttttagt atactcgttt tttctgagtt
    12781 ttacattaaa aaattggaac tgcgattcaa atcgcagttc caattttaaa agcgaatcat
    12841 cagattgtca aaaacagctg attcagctat ttttattttc tgtgttttaa cgcttattat
    12901 tcgccttggt tcaagaggat tggtaaagta ttcgccaatt cttctttacg tacttcaacc
    12961 atttcgccag ttttcttgat tttcacttct acgattccat ccactgcttt tttaccgaca
    13021 gtgattctga ttggacagcc aatcaaatca gaatccgcga atttcactcc tgcgcgttca
    13081 tttctgtcat caaccagtac ttcatagcca gcttttgtca tcgcttcttc tagttcattc
    13141 gtcaggcttg tttggtattc gtcttttaga ttcatttgga cgatatgcag atcaaatggc
    13201 gcaattcctt ttggccaatt gattccttgt tcatctgaat gttgttctac gattgctgat
    13261 aataaacgac ttacaccgat accataacag cccataatca caaatttttc tcgtccattt
    13321 tcgtctagta cagttgctcc catagattca ctgtaacgag tgccgatttt gaatatatgt
    13381 ccgatttcga ttcctcgagt aaaggcaaga acaccgttgt tgtctggtga aggatctcct
    13441 tcttgtacaa aacgaagatc ttcataagaa agcacagtga aatcgcgttt tggattcaca
    13501 tttttatagt ggaatcctgt ttcgttcgct ccagtaatgg cattcgctaa atcttggaca
    13561 taacggtctg catatacttt tacgtcatct gaaacaccga ctggtccgac agaaccaaac
    13621 tcagcaccta gatatttttg tgcttcttct tctgttgctt cttctaaaaa gtcagcagat
    13681 aaaaagtttt tcagttttac gtcattgact tcatggtctc cacgtaccaa aacaaggaca
    13741 ggttgttcat ccgcaatgaa caatacagac ttgatgattt tttgaggttc aacagaaaag
    13801 aaatctgcta cttcgtcaat tgattttacg ttaggtgtag ctactttctc caattcaagc
    13861 tgtgtttcat gcgatttttt tgatacatag tagcttgtag ccatctccaa gtttgcagca
    13921 taatcacttt cagtcgaata acagatcgta tcctccccga tttctgagat cgccatgaat
    13981 tcctttgagt ctttcccgcc cattgcgccg ccgtctccga tgatcgagcg aaattctaag
    14041 ccacaacgct tgaatacttc ggtataggct ttttcgtaat ctttatatgt ctcgtccaaa
    14101 ctttcttccg ttgcatggaa agaatatgca tctttcatga taaactctct tccgcgaagc
    14161 aaaccgaagc gaggtcgttt ttcgtcacga tatttaggtt ggatttgata aagatttaaa
    14221 ggtaatttct tatatgaatt gatttcatta cgcatcaaat cagtaaaagt ttcttcgtga
    14281 gttggtccaa ggatcatttt tcgatcattg cggtctttga aacgatacaa gtttggtcca
    14341 tatgtttcgt aacgcccgga ttcttcccaa agttctgctg gcaagatggc aggcatcagc
    14401 atttctaccg ctccgatttt ttcaaattct tcccgcataa tgcgtttcag tttttccaat
    14461 acacgatttg ctaatggcag atatgaataa atacccgctg atacttggcg gatatatcca
    14521 gctcttagca agatttgatg gcttaatact tctgcatcat ttggaacttc gcgtaatgtt
    14581 ggaatcaaca tttttgattg tctcattcta tatactcctt tatttcctca aaatagttat
    14641 cgtttgttat tataccctat ttgtcaactt tttctagaaa aagaatcgtt gaatatcgtt
    14701 ccatgtaact agcaccatca acaacattaa aaatccaaag ccagctaatg tcaatattcc
    14761 ttctttttct tgacttaatg gtttcccgcg aatcccttca aaaatattca agactaattt
    14821 cccgccatct aaggcaggaa tcggaagcag attgacgatt ccgagattca ttgaaagaag
    14881 cgccatcaaa ctaataacag ttgttacacc ttgatttgct gcttctgaag acaattggta
    14941 catcatgaca ggtccgccta atttatctaa actgaaacct gtaaatagtg atcctaaggc
    15001 tttgaaaatt tccaatgaac cgctgaaagc ttgacgcgtc cctccaatga tcttatccat
    15061 aaaacctgta ttcattgggg cttttatacc aagttggcca actttttcgc catttgactc
    15121 tacagatttc ggtgtcacgt cgacagattg cacctgacct tctcgttcga tcttaaagtc
    15181 taatgtttta cctggatttt tcgtaatgac tgttgtcaga tcattccatg aatggatttc
    15241 ttttccgtcc acactgacta cctcatcatt ttcttttaag cctgcttctg ccgcagctcc
    15301 attaggcatg atctctccta cgcgattagt gttcgtcact tgaacaccac cttgcataaa
    15361 tgccagaatg atgaataaca cgattgccaa aataaagtta ttcatgggtc cagcaaagtt
    15421 ggtcagcata cgctgccaca atttagccga ttggaactgt acgtcttttg gcgcaattct
    15481 gatttctgtt ccgtcgtttt caataatcgt cgcatcgtga tcaacagggt aggttactac
    15541 ttctgtttcg tctccattca cataaccagt gatagtcagc tcatcttcta aatcataacg
    15601 gctcaattcc atcgggatag catttgtcaa ttggattttc ttacttaaat ttatcttctc
    15661 tacgatgccg tcagaattta gtaaaagaga aagaggcatt cctggtgcca tttctgtttc
    15721 atcatcccca ttgcctgcca ttcgaacata accgccaata ggtaataggc gaagcgtata
    15781 tgttgtcccg tcttttgctt gatgcccata aattttcgga cccataccga tagcaaattc
    15841 gcggacgagg attcctgatc gtttcgcaaa gaagaaatga ccaaactcat gaacaatcac
    15901 taatatacca aaaacgatga taaatgtcag aatcgttttc atagcttttt tctcctttac
    15961 ttgttttttg tgttttttat aaaacaacga taaaacacta taattttacc atagtatacc
    16021 aaagacacca atagtatcaa tataatgaaa aataaaaacc tgcgtctttt atgaaattca
    16081 caaagaaacg caggtatact tactaaataa tgccaaataa atgcatgata ggaaatacaa
    16141 acagcaaact gtcgaaacgg tctaagattc caccatggcc tggtaagata tttcccgagt
    16201 ctttcacatc ataatgacgt ttgattgcag attcgaccaa atcaccaaat tgtccgactg
    16261 ctgaaaaaat aatcgtcatc agaagcatga caaacatacc atgattgaat agttcttttg
    16321 ctgggtatag caataaataa agaaatgcga ctacaacagc actaccgata ccaccgagcg
    16381 caccttcaat cgttttgttg ggcgaaatat caggacttaa cttatgctga ccataacgtc
    16441 gaccaaccat atatgctccg atatcagttg cccaaacaat aaatagacca aatatcaaaa
    16501 cagccaagct ttctgttcgt gcattgacaa aattctggaa acctattccc acatacaagc
    16561 tgacaagcac aggaaaacct gcttcatcaa tcgtatacgt atttttagaa ataactgatg
    16621 ttcctaaaag aatcataact ataagataaa ataacataaa tgtacttaca ttctctggaa
    16681 gaaagaaaaa ccatctttct tttggcaaaa caagtaacac tgcaccaacg gcggataaaa
    16741 ctccttcaaa acttaagagt gtcaatcctt tcatccggaa cagctcgtaa actcctacta
    16801 ccgctaagat tgctgctgta agctcaaccg ctatgcctcc gatccatata atcggaataa
    16861 acaagactag cgccacagct gctgtgatca cacgttgttt catgactgat cccctttctc
    16921 atcttctgtt ttttttacac cgccgaatcg acggtctcga ttttgataag aggcgattgc
    16981 ttcttcaaga tgcgcaccat caaaatcagg ccaaagcgct tttgtaaaat acagctcact
    17041 atatgcgatc tgccataaca gaaaattact aattcgctct tctccacttg tacggatcat
    17101 cagctcagga tcttgtaact ctttaggcaa gaaacctgtc attaaatgct tagcaatcaa
    17161 ttcatcatcg atttcttctg cgtgtatttc tccttttgct acttcttcgg caatttcttg
    17221 gacagcagtc acgatctctg ctctacttcc ataattcaaa gcaaaattca ataccattcc
    17281 agtattgttt tttgtttgct caattgcacg tcttacagca tcttgcgtat gttctggcaa
    17341 tacgttttca taacccatga catgaacttt gacattttct ttaatcaatt ctggtacgaa
    17401 cgtatcaaag aagtcgacag gtagttgcat gagaaaactt acttcatctt ttggtcgctt
    17461 ccagttttca gtcgaaaagg cataaagcgt caacactttc actccaagcc ttgatgcttt
    17521 ttttgtgact ttctttactg tttccatgcc ttctttatgg ccagcaactc gtggcaaacg
    17581 acggttttgc gcccaacgac cattgccgtc catgatgatg gcaatgtgct gaggaattgg
    17641 tccatcggta ttaaattgaa attcgctttt ttcttgaata tatttgtttt tttgcggaaa
    17701 aaaacgtaac attctttttc ctcctatact taaaagattc ccactatctt aagtattata
    17761 gcaatatcta actgtttttc ctatgaaatc attgtttttt tatttaaaaa ctgaataatt
    17821 ttttcttttt ttaattttta aataaaagaa atataaataa aaacagagga agcggaatga
    17881 tccgcccctc tgtttttatg attttattaa acttccaata attctttttc tttatcagca
    17941 gcgatcttat ctacttcttt aatgctgtta tctgtcaatg tttgtacgtc tttttctaat
    18001 ccgcgcaaat catcttcggt aatatcacca tttttttgtt gttttttata ttcatcgatc
    18061 gcatcacgac ggatgttacg aatcgcgatt tttgcatttt ctgcttcttt tttcacatct
    18121 ttagctaatt cttttctgcg ttcttctgtc agttgcggga taactaagcg aatgacattt
    18181 ccatcattgg ttggactgat tccgatatca cttgccataa tagctttttc aacatcttga
    18241 agaatgctct tgtcaaaagg tgtgatcatt aaaacacgtg cttctggaat ttggattgat
    18301 gccatttggt tcaatggtgt tggcgcaccg tagtagttca cagtaatacg gtccaaaagg
    18361 ctagcgttcg cacggcctgc gcggatttgc ccaagttcac gttgaagatt ttgtgctgct
    18421 tttttcattt tttcttttgc ttctgtcata attgcatctg ccatttttat ttccccctta
    18481 cagttgttcc gatattttcg cctaagattg cacggcgaat atttccgtgt tcatttaaat
    18541 tgaagacaag cagtggaata tcattatcca tgcttagtga acttgcagtt gaatccatga
    18601 cttgtaatcc tttggcaata acttccagat gagtcagttc ttcaaatttt actgcatttg
    18661 catctacttt cggatcagca gaataaacac cgtctacatt gtttttagcc atcaggataa
    18721 catctgcgcc gatttctgcc gctcgtaatg ctgctgttgt gtctgtcgag aagtacgggt
    18781 tgccggtacc gcctgcaaag ataacgatcc gtcctttttc taaatgacgt tctgctttac
    18841 ggcgaatata tggctctgcg atttgacgca tttcaatcga agtttgcacg cgtgtcggta
    18901 cacccacgtt ttccaacgta tcctgtaaag ctaaggcatt cataactgta gctaacatac
    18961 ccatgtaatc agcttgagca cgttccatgc ccatttgtgc tccgatttgt ccgcgccaga
    19021 tatttccgcc acccacaacg attgccattt caacgcccag ctcgtgaact tctttgattt
    19081 cttggatgat ttctttgatt actggtggtt tgattccaaa tcctgcatcc ccagctaaag
    19141 cttctccact caattttaag actacacgct gatatttcgg tgtgaccatg ttcattcctc
    19201 caatattttc tattgccatt ttaccatact tagatgattt cgacactcta agactggttt
    19261 ttcttgtttt gcttaaaaaa agggagcgca caaaccgtgc gttcccgtct gttattcaac
    19321 agaattattt tttcacttgg ctcataactt cttctacaaa gttatcttcg cgtttttcga
    19381 taccttcgcc aacttcgaaa cgtacgaatg ttttaacagt tgcgcctttt gatgcaacgt
    19441 atttttcaac agtcatatca ggatctttaa cgaatggttg gtccaccaaa gcgatttctg
    19501 ctttgaattt cttcaagcgt ccttctacca ttttttcaac gatattcgct ggtttgcctt
    19561 cgttcaatgc ttgttctgta agaacagttt tttcatgttc taattcagct tctggaattt
    19621 gtgattcgtt tacataacga ggattgatag ctgctacgtg catagctacg tctcttgcaa
    19681 ctgtttcgtc agttgttcca tctagaacag tcaatacggc aatacgtccg cccatatgca
    19741 agtatccacc aaatgcagca ttgtcgtctt tttctacaac ttcaaagcga cggaagctga
    19801 ttttttctcc gataacttga gttgcttcga tcaagtcaga ttcaattgta cctttatctg
    19861 ttttgatttt cattgcagct tccatgtctg ctggtttgtt ttcagcaaca agttctgcaa
    19921 tttcttttac taaatcttgg aacatttcgt ttttagaaac aaagtctgtt tctgagttta
    19981 cttcaacgat tgctgcagtg ttacctttca cagcaactga agccaatcct tcagctgcaa
    20041 tgcggtcatt tttcttcgca gcctttgcca ttcctttttc acgtaaaaga tcaactgctt
    20101 tttccatgtc gccttctact tcaactaatg cttttttcgc atccatcatt cctacgccag
    20161 tcatttcgcg tagttctttt accattttag ctgtaacgtc tgccatgttt aactcctcct
    20221 gtgtgttttt ctttttaaaa aaagctgctt caaaggagag tgaggcttgt cgcccagcct
    20281 ttgaaacagc tccatcattc aaaattattc tgctgaagaa ttgtcgcctt caacaacatc
    20341 tacgatttct tcgattgatg ttgctgtgtt ttcttctgtg aaatcttctt caactacttg
    20401 atcttcacct tggtttcctt cgatgaaagc atcagccatt tttgaagtaa tcaatttaac
    20461 ggcacgaatt gcatcgtcgt ttgaagggat tactacgtcg atttcatctg gatcgcagtt
    20521 tgtatcaacc atagctacga ttgggatatt taatttgtgt gcttcttgaa cagcaatacg
    20581 ttctttacgt gggtcaacga tgtacattac atctgggatt cttggcatat cagcgatacc
    20641 gcctaagaat ttttcaagac gttcacgttc tttgttcaaa ccagcaactt cttttttagg
    20701 tagaacttca aaagttccat cttcttccat tgcattgatt tgtttcaaac ggctgatacg
    20761 tttttggata gtatcccagt ttgtcaatgt tccgcctaac caacgatggt taacgaagta
    20821 ttgtcctgca cgagttgctt cttctttgat tgcttcttgt gcttgttttt ttgtacctac
    20881 gaataatgct acgccgcctt cttcagcaac gctcttcatg taatcataag ctgcatctac
    20941 taatttaact gttttttgca agtcaatgat gtagattccg tttctttctg tgaagatata
    21001 tttcttcatt tttggattcc agcgacgagt ttggtgacca aagtgtacgc cggcttctag
    21061 taattgtttc atagaaatta ctgccatgtt tgtttcctcc gatttggttt tatttttcct
    21121 cttcttatct tctaccttgc cggcaaactt tttcaagcac ctaccgacaa tccaataaga
    21181 atgtggattt gctgatgcat aaagcaccct cagctattat acagacaaaa gatccgtatc
    21241 gcaagagcaa atatactttt ctgctcaaca ttcaatagtt tacctgaaag ataaaaagaa
    21301 ttcaagaaaa acagtagatt tctctttgtt tctttattat cctttttcca taaaataatt
    21361 ttaggtataa aagacgaata ttattgggca atccttcttt tttttgttat gatacatgtg
    21421 aaatctttcg taaaggagaa agaaaatgcg caaagctcaa agacatttgc tgattaaaca
    21481 agtcattgaa gaattcccga tccgtacgca agaagaacta ttaaacaaac ttgggcatta
    21541 tggcgttacc gccacgcagg caacgatttc tcgagatatc cgtgatctaa aaatcgtgaa
    21601 ggcacctgat gaaaatggcg tttcccgctt cgtattgttt cgcgaaaaag gaactcctga
    21661 gactaggact gaggaagagg atcggctggt tcaaatgatt gaagacattg tattgaaagt
    21721 cgaacgagtc cactttttga cgatcgtcaa taccttgcca gacaatgctc atttatttgc
    21781 atctgtttta gatgagatca aacctccctc tattgtcagt acaattgctg gattcgatac
    21841 gatcatggtc atctcggaaa atgaggagga cgcaaaacga gtagaagaat ttcttcacca
    21901 tccaactgaa gtatcacttt tttaatcaga gcacgtattc ctaatatgga atgcgtgttt
    21961 ttttattttc aatattttcc ttattaaata aacctttaca ctctttacaa aaatacatca
    22021 ttttttattc aattttttca acaccttgat tgaatcacaa taatcatcat ttatattgga
    22081 tgttaacaag agcagcttct tgctctttgt gtatttcaaa aaagaaatga aaggaaatca
    22141 tatgtataaa ttattaactc ctggaccatt gacgacttct gaaacagtga aaaatgctat
    22201 gctgatcgat cattgtactt gggatcaaga atacaaagaa attacacaat ggataagaaa
    22261 aaaattattg gatcttgctc aagtatcgga aggaatatac acaacggtct taatgcaagg
    22321 tagcggctcc tttggggtag aatcggtatt aagttctgtg atcaggccag aagatactgt
    22381 actgatttgt tcaaacggcg catatggaca acgaatgatc aacatgtgcg aatgtctgaa
    22441 actgaactat accgtttatg aggtatcgga acatcaaatc ctccaagctc atgtgattac
    22501 acagctgatt gaagagaatc cctctatctc cgcactagca atggtccata gcgagactac
    22561 ttccggtatt ttgaataatt tggaagagat tgctgctgtc acacaagaaa aagatctttt
    22621 gtttatagtg gacgcgatgt caagctttgg tgggataccg attcgtgtag ccgaactagg
    22681 gattgatttt ttgatttcca gctcaaacaa atgtattcaa ggtgttccag gcttttcttt
    22741 tgtacttgct aataaagcgg aactagaaaa gcgaaaaaat gtgagtcgaa gtttgtcact
    22801 tgatctatat gaccagtacc gcgtgatgga aaacgagaat ggcaaatggc gtttcacttc
    22861 ccctacccat acggttttgg cttttcaaca agcgctgaag gaactagagg cagaaggagg
    22921 aatcgaaact cgatattcac gttatctcgc caataatcat gtactacgac aaaaaatgac
    22981 agagatgggg ttccagcctt tcattcaaga atatcagggg ccattcatca cctcttttct
    23041 ttaccctaag gactggcgat ttgattttaa tcatttttat cagtatttaa agcaaaacgg
    23101 atttgtgatc tatcccggga aaatcagcga tcatgaatgt tttcgtatcg gaaatattgg
    23161 cgagatctat ccggaagata ttttggaact gacagcaatt atcaaagact ataaggagaa
    23221 cgttaatgat taaaactgta atttttgatt gggcaggaac aactgtggac tttggctgta
    23281 tggctcctgt ccacgctttt agaaatgctt ttctagaaaa aggaatccaa ctgactgaca
    23341 aagaaatccg cgaaccgatg ggaaaattaa aatgggatca tatccaacag cttctttccc
    23401 tcccttctgt caaaaaacaa tggatagcta tttatggaca actacctcag gaaaaagagg
    23461 tggaggaatt gtatcaacaa tttgaacatt atctgtttaa agatttggtc aagcattcta
    23521 ccttgaaacc cgacacattg gaaacgatcg aacggttgag aaacgctggg atcaatattg
    23581 gttccacgac tggatttact gctcctatga tgacaatcgt agcagaaacc gcaaaaaaag
    23641 aagggtattc accagacttc atggcaactt ctgaagacgt cgaagggtat ggtcgaccgt
    23701 ttccttatat gatccataaa aacatgcagt acttcaaaaa caagtcggtt gatgaagtaa
    23761 tcaaagtcgg agatacggtc tcagatatcc aggaagggaa aaatgccgga gtgttgacag
    23821 taggtgtaat tgaaggtagt tcgctaatgg ggatttctta tgatgagtac caaaaattag
    23881 agatggggaa aaaagatcgt ttaaaacagt ctgttgctct tagattccaa caagctggcg
    23941 ctgatatttg tgtaaacaat ttaaaagagt taacagaata cattttgtac gctgacaaga
    24001 atccagaatg acttttatac aaaatcagag gtcgtgaaaa agctgtactg catcaagtaa
    24061 taagaacagc caaacaaaaa tagctcctca tatttttcgt ttggttaggc ttattaccgc
    24121 agatgcaagc ttttgaacac cgtttattcg aaaaaaaaag ggagctgtga cacgactttt
    24181 gtcacagtcc ccttatttac aaacaaacag tgtttaagag acaacctctc cactaaacgg
    24241 tgttcattca gctgactctc ggtatttgct caaaaaacga taaaatttga aaagctattt
    24301 tctcttttgt ttctctaata ctcggatcag aacgctgatt tcacattctc tttttcttac
    24361 atcttatctg gtgcatgaag tcctagcaaa cgaaggtctt ctttcaataa tacagtcact
    24421 gcataaacta gagctaagcg tgcttctttt tgttcatcat cagctaaaat cttcgtatga
    24481 gcatagtatt tgttgaatgc ttgtgctaat ttgattgcat gtttcgcaat cactgacggt
    24541 tcgtattttt ccccagcaga caagaccgtt tcagggtatt tttgaactaa tttaaccact
    24601 tcccagctgg tatcgtcatt caatgcatag tctgctgttt ctgaagggac aaatcctgct
    24661 ttttccaaca ggctgactgc acgagcatgt gtatattgca cataaggtcc agtttctcct
    24721 tcaaatcgaa caacttcttc caggttaaag tcaaatgtat tcagtcgatc gtttttcaaa
    24781 tcgtggaaaa tgactgcccc aaccccaact tgtttagcta cagcatcttt gttttccaaa
    24841 tcagggtttt tctcgctgat ttgttcttta gcagattgga ttgcttcatt taatacttct
    24901 tctaataaga cgatctttcc tttacgagtt gataattttt taccaccttg cgtgatcaaa
    24961 ccaaatggaa tatggcgcat atcgtcagac cagtcaaagc ccatttcctt caagacagct
    25021 ttcaactgtt taaaatgata gctttgttca ttccctacta catatagaga ttgtttgaag
    25081 tcgtaagtac gtttacggta caatgcagca gctaagtcac gtgtaatgta tagtgtcgca
    25141 ccgtctgact tcttaatcaa cgctggattc aggtcataag cagataggtc aacgatctct
    25201 gcacctttat cctcgttcag caaatgtttt tcttctaaaa gtttgacgat ttcatccatc
    25261 ttgtcattgt agaaagcttc accgttcaac gaatcgaaac gtacttccag cagatcatag
    25321 attttattga attctttcat cgattcatca cggaaccatt gccataattg aatagcctct
    25381 tcatcgcctt cttccagacg tttgaaccaa gcacgagctt cttcatttaa ttctggttct
    25441 gtttcagcta cttcatggaa ttggacatat aaacgaagca attcattgat tggttctgct
    25501 ttaacagctt cttctgtacc ccattttttg taagcgacga tcagttttcc aaactgtgtt
    25561 ccccagtcac ctaaatggtt gatgcggatt ggctgataac cgattttttc cataatgaaa
    25621 ccgatcgaat taccgataac tgtcgaacgc aaatgtccca ttgagattgg tttggcaata
    25681 ttaggagaag acatgtcgat tggtactgtt ccttgattcc cgatattgct atccccataa
    25741 tgttcttttt ctttcactac tgtttgcaaa acttttttgc tgataagttc tttattcatg
    25801 aaaaagttca agtaaggtcc gacaacttcg attttttcaa agttggcaga atcgattttt
    25861 tctgctaaat ctgcagcgat ttgctgtggc gcttttcggt aaacttttgc taatgaaaag
    25921 gctggaaatg caacatctcc gtgttcagct gattttggat tttctagtaa ttgttcgact
    25981 tgttccagtg ttaaatcatc tttgacagcg tcatagacag cttttgcgac aagatcttta
    26041 ttattcatct ttattcctcc taaagtgctc ccttgattgt taaacaaaaa aaatctctag
    26101 cgacggcata cttagtatgc catcactaga gacgagattt cccgcggtac cactccaatt
    26161 gtcctaaaaa aggaccagct ccatctgata tcggtagacg accgtctgtt taaaacagaa
    26221 ttctccaagt gcgcttcgtt gtatcttctt cattcggctt ccaccacttc cgaattcgct
    26281 agccaagaat gatacaagta ctctcttgtt caacaaatct tagtcttatt aaactttctt
    26341 gaattatatc agaaaaaaaa acgaaaggct agtcgtttct gataaaaaaa caatccagat
    26401 ggcctaaagg agaagaaata ccacctggat agctataaat catttcgtaa atacgaaaga
    26461 cttaacaaat taatcagcta cgataatcgt tccttcttca gaagctaaaa gattctcgat
    26521 attttctaaa gaagtgatga ttgccttagc gtttggtttt gcttcaacaa atgcaatagc
    26581 tgcctctact ttcggaagca tgcttcctgg agcaaattgc ttttcatcaa tgtattgttt
    26641 catttctgaa acagtaacag tttctaattt cttttgatct ggtttttggt aattgacata
    26701 cacattgtct actcctgtca atacgatcag caaatccgca tcgatgattt cggctaattt
    26761 ttctgaagca aaatctttat cgattacggc ttctcgtcct tctaatccag tagctgtttc
    26821 tacaacagga atcccaccgc caccaacaga gactgtgata actccttgat cgaccagcgt
    26881 ttcgatgaca cgtgcttctt taatcgagat gggtttaggg gaagcgacta cttttctcca
    26941 tccacgtcca gcatcttctt tgaatgtcac agtggagtca gcattcattt gttctttggc
    27001 ttcttcttcc gtgtagaatg gaccgactgg tttacttgga tttttgaatg aaggatcatt
    27061 ttcatccaca ataacttgag tgactaaaga aaccacatct ttatcgatcc ctttttcctt
    27121 cagtacttcg cccatggcat tttgtaacca gtaaccgata gatccttctg tcattgcaac
    27181 acatgtatct aaaggcattg ccggtgtttt ctcagaatca gcagcttgct gctgaatcaa
    27241 taggttaccg acttgcggac catttccgtg ggagatgatc aattcatctc cttgttcgat
    27301 aaatttcact aaatactttg ctgtttccat taacgcttct tgttgggctt ttgcacttgc
    27361 atccgtagac aagattgcat taccccctaa agcgacaact acttttcgtt tggccatttc
    27421 attcgtcctt tcttcagttc taccgaattt tctagataac aaaacgagcc agcgttttgt
    27481 gattttccct caatgctgac tcgttttttc gtgagatgaa tgtggttatg cttaaacgcg
    27541 agggataaac aagttaccta atgttgctgc catgatcgct ttgattgagt gcatacgatt
    27601 ttctgcttgg tcaaattgac gagcatattt gctgcggaag acttcatctg ttacttccat
    27661 ttcagtgatg ccaaagcgtt ctttcatttg ttcaccgtaa acagtgtttg tatcatggaa
    27721 agctggcaag cagtgcaaga agatcaaacg atctgtgttg tgtgtttttt ctaccatttc
    27781 catattgatt tggtaaggtt tcaacaattt gatacgttct tcgaatttat cttcttcacc
    27841 cattgatacc catacatcag aataaaggac gtctgctccg tctacacctt tatcaacatc
    27901 gtcggtaatc atcaattgtg caccggattt ttcagcaaag ccttctgcca ttttgacgat
    27961 ttcttcttca ggttgtaatt cttttggtgc aacgatacgc atattcgctc ctaaaattgc
    28021 acctgtgact aataaagagt tagccatatt gtttcgacca tctccgcagt aagcaacagt
    28081 gataccttct actgttccaa agttttcttg gatagttaaa aagtcagcga tcatttgtgt
    28141 tggatgccat tcatcagtca agccattcca aactggaaca ccagagaatt ctgctagttc
    28201 ctctaccatt ttttgactga atccacggaa ttcgattcca tcaaacatac gacctagtac
    28261 tttagctgta tcttctgtgg attctttttt acctaattgg atatcatttg cacctagata
    28321 ttcaggatgt gcacctagat cgatcgctgc agtagtaaat gcagaacgag tacgtgtaga
    28381 tgttttttca aataaaagcg caatattttt tccttctaga tagtgatgtg ggataccacg
    28441 ttttttcaag tctttcaagt gttctgaaaa atcgatcaaa tattgtaatt cttcttttgt
    28501 aaagtctttt tctgctaata agcttcttcc ttggaatact gattctttca tattaaacat
    28561 tctcctttag attgttttta tttaagatta aagaggaaat cccgacggca gctgacagta
    28621 agaccgccgt caggaaacaa attacttcaa gtcttcacgg acaagtggtt ggctcatgca
    28681 gcgtggacca ccacggcctc gtgacaattc acttgaattg atttctaaca ctttgatgcc
    28741 atagctacga agcaattcgt tcgatacata atttcggtta taagtgacta caacacctgg
    28801 agcgattgcc aatgtgtttg atccatcatt ccattgttct cgaggtgcaa cgatctcatc
    28861 tccattacca gttgggatca gtacaagatc atctaatcca agagcagctt tcatcgtttc
    28921 gtgtaagtta tctgaatgag taatcttgat atcatcacca tctggttcga ttgtaaagac
    28981 atccatctta ccgtctttac tttgaattgc tggatggata gtgaatttat cgtgatctac
    29041 cattgtaaat acggtatcca aatgcatcat tgcacggttg tttggaattt tgattgctaa
    29101 cactttttca aatcctgaat tttttgcgaa taggtggcgt gctaattttt ctaaagcttt
    29161 cgcattagtt cgttgagaaa tcccaacagc tactacttta tcgcttaaga tcaattcgtc
    29221 tccgccttcg atatgatctg gattttcacg atccaaccat acttcgattc ctttatttgc
    29281 aaatcttgga tgatgtttca aaatatattc tgtaaacatc gattcacgac gacgtgcttc
    29341 aaaagtcatc ttattgactg tcatcccatt tcccattgat gcggaagggt cgcgtgtaaa
    29401 gtacaagttt ggcattgggt ccatgtaaaa tggatagtca tcgtctgctg acagatcgta
    29461 tagactgcta gaacgtactt caatatcttt tgtacgaacc ccagccatga ttttatctac
    29521 catttcttgc gtttccattg atagaaggaa ctcatgaaga ccctctctta cagcattcga
    29581 tgcaatatga gattcatcca acattttatt caagaattgt tctttgacat tgcctgcgtc
    29641 aatcgcttct gccgctaatt tttccaagta aagagtctcg acgccttcat tttgcaatgt
    29701 ctttgcaaag ttgtcatgtt cttcttgagc aatcggaaga tatggaatat catcgaacaa
    29761 cagacgatcc ataatatctg gtgtcaaatt ttccacttct tgtccaggcc ttttcagtaa
    29821 aactgtcttt aatttcccta tttcagagaa aacgtgaata ggtttatcca tgttgtgttg
    29881 cctccttctt tttgattaca tgtataggat atcctccttt tgtaatcact ttcataattt
    29941 tgtctcattc aaaatgagac attcctcaca ttaatattcg ataattaaat aattaaacgt
    30001 ttttctattt ttaagcgtaa tttattcatt ttttattctg tatacacttt caaaaaaata
    30061 tttattcatt gaaaaaaatt ttttgaataa attaaaaaaa taaattatat tagcgttgtt
    30121 agcgtttact atatgtatta ttgttgtttt ttatacacaa atcattcgct tcaaaacaaa
    30181 ttattcaata ccattgtata ttttttacat aataacaaat tatatttgta aagtattaaa
    30241 acttgtttct aatgttggta tgttaaaact ttacaaattc tttaaaaaaa gtgacaataa
    30301 atatagtgaa caataaggag aggacttttt aatgcgtgtt aataaaatcg attttcactt
    30361 ttcaaaactc agatatcaac ctgattttga acatttctcg gatgaagagt tccaacagat
    30421 caaggaacat actgttcttc gttcttataa aaaaggacag atccttttcg acgatggtga
    30481 tcccagacaa cggttgtata tcttgaccaa aggactcgtt cgtttagaac gttatgatga
    30541 aagtgcaact tattactact atgactatgt gaatacaaat aacctttttc ctatgtcagg
    30601 aatgtttgga gaagagacct acacttatac agctcaagcg atgactgata ttgaaacatt
    30661 ctaccttcct gtttcctact atgaaaaatt agcacgaaaa aatcccgaac agttgatcta
    30721 tatgatacaa aaaatttcta aagtagttga aatacatgaa ttgcgtatcc aaatcggatt
    30781 gacctctagc gcctttgacc gggtaaaaca aaatttattc attttgaaag aagaattggg
    30841 cgtaccaaca aaagatggtc atatcaccat tccttatccg atcaccttaa aagaattagc
    30901 agtgaatagc ggcacgacac gtgaaactgc tggacaagta atcaaacaac tacgtgattc
    30961 cggactgtta gattatgaca aaaagcgttt tactttctgt aagacagcta ctactccagc
    31021 tatgagagaa taacgcgaac aaaaataagc agtgaccctg atatttatca gggtcactgc
    31081 ttattttcct ccctaaaact tctgaaagat ccggcagttt tagatcactg ggcaagactc
    31141 aaagattttc tatgtgtgtt tcagttatgt aatattcact gtttgcaaaa aatactgata
    31201 gattaactag aggaagcgtc ttgtcctcat ccgacctaga ttattcgata ttcctcgaca
    31261 ataaacgatt aatcagtgag ggcaatcaga ggaacggata atgatgaata agctgtaaaa
    31321 aatagggctt tgacaaaagc gtgtcacagc ccttatttcg attaaacggt gtgtacctgt
    31381 caactcttcg gtcacaagtc ataatgttca taaacatgag gagctgtttt ttgaaattgt
    31441 tccttgtgaa tcagagttaa acgacaggct tacgaactct tgattaaacg gcgttcaaaa
    31501 gcttgcatac gcggtaataa gaacagccag gtcaaaaaca tgagaagccg tttttcctgg
    31561 gctgttctta ttacttgatg cagggcagat ttttcacaac ctctttattc agataaaacc
    31621 aagcttggat cagcattcaa ctgatagcta gcaaaatttc ttttttgcat ttccacatgt
    31681 gctgctgctc caatcattgc agcattatct ccacaaagtc gaagaggggg aatcactagt
    31741 tctacctcag ggagtttagt tgccaaagca tcctgcaatc cttcacgcaa cccttgattg
    31801 gccgctacac ctccagctac aatcagttgc ttgactggat aattttgaca agctcgaagt
    31861 gttttagtaa tcaatacatc gatcacactt gcttgaaagc tagctgctaa atcatttttg
    31921 tctagatctt ctccacgctg ttgtgcatta tgcaccaaat tgataaatgc actttttaat
    31981 ccgctaaaac tgaaatcata attatcttca tggatcatcg ctcgtggaaa atggtaatta
    32041 tcttttccct gatgagctag ctgatcgatt tcttttccgc ttgggtaaga aagacctaat
    32101 actcttccaa ctttgtcata agcttctcct gctgcgtcat ctcttgtctc cccaatgatt
    32161 tcatatgatc catcttcttg catatagact aattctgtat gtcctccgct aacaagaagt
    32221 gccatcaatg gaaactggaa tggtttaacc agacgggctg catagatatg ccctgccata
    32281 tggtttacag gaataagcgg caattggtgt gcccaagcaa aagccttagc tgcagaaata
    32341 ccaatcagca acgagccgac aagtcctggt ccataagtga cagcgactgc cgataaatct
    32401 tctgccgaca caccagcttc taccagtgca tcttccaagc ataaggtgat ttgttctacg
    32461 tgatggcggc tagctacttc aggaactacg ccaccaaaac gtttatgact gtttatttga
    32521 gaagcaacga tgttagataa gatctctgtt ccatttctaa cgaccgctac actcgtttca
    32581 tcacaacttg attcaatcgc cagaatcaat tcttcattca tttcatcgtc tccgttttta
    32641 actttctgct cataatgatc gcatcttccg tcggattgcg ataatatgat ttccgtttac
    32701 ctaatatacg aaacttttct gattcataaa gttttcttgc tgcttcatta gatagacgta
    32761 cttctaaaaa aacatgcagc gaatctttta tttgttccgt aatcagtaat tgtaacaaat
    32821 gccgtgcatg cccttttcct tgttctgaaa ctgcaacagc aatatttgtg atctcgactt
    32881 catctattac tttcgagtat ccaataaagc cacagatctg gttatcttca actaaaagca
    32941 gataatcaga gtgaggctgt tggatgtctg ccaaaaactg cattttcgtc caaggtgaac
    33001 catgtggata agcattttcg ctaatcatcc atacgcattc tgccaagtac gcttcatcaa
    33061 aatctttttt tctgcaaatc aactaatctc actcattttc taaaagtttt atcatatcca
    33121 acgcatcttc ttttgtttca gtgtaatatc tttttttgat cgttgttgct tgaaaaccta
    33181 acttccgata aagtctttgt gcatcttgat tactcatacg cacttctaat gacatcgtct
    33241 cacagcgatt cattatagca aagttctcga tttcgtcaat aagcagcgaa ccgattcgtt
    33301 tacgctgata tgccggtcga acggcaatat tcgtgatatg gcaatctaaa ccgaacgctc
    33361 ttgaaccgat aaaaccaatc attcttccat tatcaaagat acctagatat agatgaggaa
    33421 gcggtgactt caattctgat ataaaggcac tttttgtcca tggcaattcg ccattataga
    33481 cttctcgttc gacatccagc agctctttga tatcttctgt agtcaattct cttagtacgt
    33541 aacgacgatc gatttgttcg attgtttttt ctgtataaat cattttatct tgaaaaaagc
    33601 ttctggcata cgctctaaat tttttcaaca taactttcgt ctccaggtgt gtgcgtctcc
    33661 aaccattttt cttctgcttc tacccgtttt aaatagcgag gaagaaaagc ttgtttctct
    33721 gcaactggtt cagctaaagc acctaattga gccacagtta caccacttgg aatatcccat
    33781 gctggaactg tattaatcat cgcactaggc aatatttcct ttatttcata gaagaatttg
    33841 tgacaatcac tcccgacgaa ataaatagct tcattcagct tttgtagttg tgtgaacaaa
    33901 tcagaagcag aaatatgtac atcttcaagt acaatttcta atctattttc tttccagcgg
    33961 tatgccccag cgtatacatt ttttcttcga gcatcaaaca tgggcacaat aattttatcc
    34021 acaccgatgc aattagccgc gatggttttc agactagata ctcctactag ctctttatct
    34081 aatgtataag caatcgtttt tgctgtcgtt acacctatac gaagccctgt ataagaaccg
    34141 ggaccatcag aaaccgcgat tcggtcaatg tcttttggac ttatttgaag atctgcaaac
    34201 aattggtcga ttgcaggcat cagtgttaca ctgtggttgc gtttgatatt tgtttgtatt
    34261 tgtccaagaa tttgttcgtc ttctaccaca ccgatcgcca aagtttggtt tgcagtatct
    34321 attcctaatg taatcatata tttgatcctt tctgctatga cattctcgcc ttccattgta
    34381 gcatactttt ttattctgag gatgaaaata ccaaaggcaa aactagtaca atgatacatg
    34441 attatctgct ggcgggcaaa ttttgcccct tcctgaaaca caaaaaagct gcggtatcac
    34501 ttcatttccc cacagctttt ccatctttta tttcgttgat tctcgaataa tcaactctgt
    34561 ttccacaata atctttcttg aaaccggtgc tttggaatta cttaattgaa gaatcgtctc
    34621 cactgctagc tctcccatcc attcggtata aacttttaca gtagaaagag agggcgttac
    34681 atatttcgct acactgacat cattgaaacc catcacagaa atatcttctg gtaccactaa
    34741 acctttttct tgaatcgctt tcagtgcgcc aatcgctaat gcatcattag ctgcaaaaag
    34801 cgcatcagga acatgcggat tcgtttttaa atactgcttc actgcttgat atcctgactc
    34861 gacagaaaaa tctgcttcga taattggacc ttcgtcgtag cctttttctg ccaaaacttg
    34921 ttgaaatgcc ataattctgg gatcttttag ccgctgatgg tttttcttcg tatattctgt
    34981 tccagcaagc atagcgatat gttgcgcttt atgggagaca aaatgttcaa tgactttttg
    35041 aacacttgac ttaaagtcga caactagaga gtcgattcct tgagaagtgc cgtcagaatc
    35101 taccaaaagc aaggcatttt gggatccttt catttctaat aactgagctt cgtcgaattt
    35161 tcctagtgcg atcgttccat ctgtcggaag atcactaatg gaatcccacg tttctttcaa
    35221 taaagtaacg tttgcttctt ctgccttttt ttcgattcct agacgaatag ataaataata
    35281 aagatcttca agctcttccg tatcgtcgta ccactggatc aggcgaagcg tttgcttagt
    35341 atttgctgca tttttacgat gtttcgtata atttaagcgt tctgctgctt caaaaatttt
    35401 ttgctttgtg gctaagccaa cggaaagatc aggatcatag ttgagaactc ttgaaacagt
    35461 agcaggagaa actcctgcca actgcgcaat gtctttaatt gttgccattt gtctctcctc
    35521 cttttttacg tttataaaat tgcagtaaat cgttcaaacg ctgcctgtcc tttttcatct
    35581 cgcttgaata ctccagcgtc ttccagtaca cgtgcaaaaa cctgacctac agatttttgt
    35641 acgacatcgg tgaccgtatc tttcgtcaaa tcaggatgtt ctttttttaa ttgttctgcc
    35701 cacggacgat gatattcagc catctggttt tcttctccta ataagaaatg ctctacttct
    35761 actagttctg gtttcaaacg aggtggtaaa acagcaagcc ccattacttc gatcaaccca
    35821 atgttctcct ttttgatatg ttggacatct ttatgtggat gaaaaatccc atcaggatgt
    35881 tcttctgaaa cattgttgtc tcgaaggaca aggtccaact caaagtaatt gtcccttctt
    35941 cgtgcaattg gcgtaatcgt atggtgtggt gtaccatctg ctgaaaaagc tctgatagat
    36001 actgtttcat ccgaatatgc tttccacttt tccaatactg agttagctgc ttcaatcaac
    36061 aattttttct ctgttgattg caaacggatc acagacatcg gccatttcac gactcctgcg
    36121 atgacttgcg gataatctgc tagtttgata agtttttcta tcggtgcttt tgccatagga
    36181 aattcatgac gtcctgcctg ataatgatca tgagaaagaa tcgatcctcc aacaatcggc
    36241 aagtcagcat tcgaaccaac aaagtaatga ggcaagactt cagtaatccg aagcagtcta
    36301 gcaaatgttt cctttgtgat tttcatcggg cggtgttgtt ctgataaaat gatcgaatgt
    36361 tcattgtaat aagcataagg agaatattgg aatccccagc tttcaccgtc tagattcatt
    36421 cgaataatcc ggtgattggt gcgggctgga tagttcaagc gacctctata tccttcgttt
    36481 tccatgcaaa gcatgcaggt aggatagtct acttttaccg cctcgcgttc tgctgcgatt
    36541 tgttttggat ctttttctgg cttagataaa ttgattgtga tttccagttc accatactcc
    36601 gactctgccg gaaatttgat gttttttgcg atggctcttg ttttgatgta gtcatttttc
    36661 ttacttaaat taaagaaata ctcagttgct tcctctgggc ttttcgaata gtgctgtgca
    36721 aagaatgcat tgacgactga aggtggcggt gtgagaaaat ccattaattg cgcttcaaaa
    36781 atctcttgtt ctgctggcaa ttctgaaaga acaccatttt ctcttgcctt agcgacaagc
    36841 tgatccaata agtctacaga ttcttcctta actggtctta cttcaatgct ttctagagca
    36901 tcttctccta ccatccctaa aagacgattc tgtaaatata agcggtccat ttccatccat
    36961 ccgccagctt cgatcgcaag tgtggcaaaa tcacaaatcg tttgactgat tgacatatct
    37021 cattccccta ttcttcataa ccatttggat ggctgacatg ccaatcccat gctgttttga
    37081 taattgcttt gatatctgtg tattcaggtt tccaacccag aacctctctc gctttttcac
    37141 ttgaagcgac taatcggcta ggatctccag ctcttcttgg tgctatttct gctggaattt
    37201 cttttcctgt cacttctcta gctgcttcta gcatttcctt gactgagtat cctttgctgc
    37261 tgcctaaatt gaagaagttg ctttcatttc cttctttcaa gtattccaaa gctaaaatat
    37321 gtgcagcaat caaatcttct acttgaacat aatctctgat acatgttcca tctggtgtat
    37381 cataatcgtc tccataaaca gccaatgctt ttctttgacc aagagctact tgtaaaatga
    37441 ttgggacaag atgcgtttct ggtgtatgat cttctccgat agatgcatct gcttttgctc
    37501 cggctacatt gaagtagcgc aaagcgacat agcgcatgcc atatgcttgg tcacaccact
    37561 tcatcatttt ttccatcatc aatttacttt caccatacgg atttttagga ttagctggtg
    37621 tatcttctgt gattggagac tcttttggtt ctccgtaagt tgctgcagta gaagagaaca
    37681 cgattttatt cacattgaac tcgtgcatga cttcaagtaa gatttgcata ccgtatacgt
    37741 tgttgttgaa atacatcaat ggtttttcga cagattctcc tactaaagag cttgcagcaa
    37801 aatggattac tccttcaatc ggttcctttt caaatacgga acgtagaaat tctttatccc
    37861 ggatgtctcc ttcataaaaa tgagcatctg gatgtactgc ttgtttgtga cctgtgagca
    37921 aattatctac cacagctact tgatacccct tttgaactag ctggtctaca gcgtgcgaac
    37981 cgatataacc ggctccgcct agtactaaaa ttgtcataaa aaacactcct ttgattagta
    38041 aaattgtgtt tgttgattat atataattta aaaaaacgaa gtttactttt atggtgaaaa
    38101 caaacaaagt aaaatttcgt aaattcatat ggtaaattta taataaaaca tttagtaaac
    38161 attttcaagg attttttgca aaggtttaca aacaaacgta aaactagcct ttttttctct
    38221 tttgttccat aatagatata acaaataata aatgaggtgg attcaatgaa aaaatttgta
    38281 tctggaatat tagtaggaag tctggcaaca gccgctgccg ttgctggttt ggtcgcttct
    38341 gtgaaaaaaa cagtgatcga tccaattgac gaaaaagaag caatgatcga agaaaaccgt
    38401 aaaaaagcaa tgcgcaaacg cgtttctcgt taataattat ttaaaaacac gcatgaagac
    38461 ttgtgaaaga acagataagt catcatgcgt atttttattt gtcagtcaat ataagttgtg
    38521 ctattttatc tgcctgtctc agattccatg gatctgtata aggtctagct actgctgcag
    38581 ttagccaatc cacaccttca acaggtattc catagcaata aaagtcagac tggatttccc
    38641 ctgaagcatc aatcacgcga ttcgtacctc gctcaacatc tatagcttct gaatgataac
    38701 ttcctgtatt atctgaaaat gaaaaagggc gaacaagttt gttttccttc aaatttttta
    38761 tgacaggatt acttgaacga gaaaagcttg tttgtggcaa tcgagcttca atcaaatagc
    38821 gactgctgat ttctttatct tgtagagaaa taacatagcg gttgtgcttt tgctgaatat
    38881 caaatggcgg ttcgaacaaa tgaaaaatac ccgcatctat cagtgctgct aattctttcg
    38941 tccgaatgac tggcggaccg atcgttaaaa agctatttag atgagtaaac catccccata
    39001 gtatttcttt gtattccttt gcagaaaaaa cgtgccattc aatagcctgc cggattggat
    39061 cacgccagtc ttttaatgca tcaaatgttg aagcaaatgc tcctgtgcaa ttgccttttt
    39121 ccgcttcttt tatctgccct tcaataaatg ctcggctagc ttctgcaaag gactcatcct
    39181 gataggtaag aggaatttct aaatacgacc aatcccatct ataagggatt agtgctggat
    39241 gctttccgag acactcctct gaagagaggg agagaaaatc atgctcaaaa tttttctttg
    39301 gaatcggcaa atgatattct tcgatgattt tcttgtaata aaacaactca acgtcttttt
    39361 tcagatagtc aaaaaatgtt tcgccagtca aaaatcccga ctgatgccat tgctccaggt
    39421 tttcttttgt tagtaaccgt ggccatgcca ttgatccgcc ttgcttttgg tttcttcctc
    39481 gagggtaata agggagcccc cttcttgatc cactgtatac aatcggttcc ttgcctgatg
    39541 gatgatagac aagttttcct ttttcgttct cgaagcgccc ttctcttgat actgtaaaca
    39601 atccgacata atcaaaaaaa cttaagccta gacctcttaa aaagacattt tctttaggcg
    39661 gtatcttcga aagatcgaca tctgcaggat tagaaggaag ctgatacagt aaatcatttt
    39721 tctttgcgta gtctacccac actctttctt cttctgtctc atcattttcc cagtgaccgc
    39781 ttgctaaaac aagctgatcg atagaatagc tttgctgatc tgtctgtaaa agataaccat
    39841 cttttctttt gctgactttt tttactaaag aataaacaaa ctgaatagaa gctggaaatt
    39901 cttcttgcaa ctttgagaaa aaccagcgtt gatagagtcc gtataaacat cgagtagatt
    39961 gctgatcttt ttccagacga ttgatttctt ctataattag ttgcttattt ttggttaccg
    40021 tctgttcgat ataatctgta gcaggtcctt tactccattg aaacaagttg ggtccctgtg
    40081 ttaccaatcc tccactggac aatgtttcat ctgtaaaaag cgtcacttgt tgagaaacag
    40141 aattcattaa taactccggt ggctgattca accgccaaac tcgacctcca ggaccattgg
    40201 gatcgaaaag aaaaagttca agagaatgtc tgtcctgatt attatggaga atcctttctg
    40261 ctatacttaa tcctctaggt ccggcaccaa tgatccctat tttcatttgc atgcctccat
    40321 ttcgataaat tttttcaata aaacagcatg gttctgatgt tcattttttg caccataaac
    40381 aaaagtaatg actggatgtt ctttcataag ttgactgagt ttaaaaatag cttgcttctt
    40441 ttcttcttcg aaaatcaatt cttgctggta tttctttgca aatgaagcaa atcgttctgg
    40501 tacatggtca aaagttttgc gtgcttcatt actaggtgca atttctttca accacagatc
    40561 taactgcgct ttttcttttg aaattcctcg tggccagaac ctatccacga gtattctata
    40621 gccatcctct ttttcagcat caaggtaaac acgttttaat ttgatcatag ttgtttcctt
    40681 ctttctgcct tttcgcttag cttatatatg tagataatag cacaaaataa aaaaaatgaa
    40741 cggcacaact atccattgcg ccgttcatgt gatcttggtc aaaatctaat gattgattcg
    40801 gtttttaaag ctgtcataca atcatctgtt ttatactttt ttacttttga tttttccaga
    40861 ccatccgtca tatccaccct taagtaaata aatctcttga taacctgctt tacgtaattt
    40921 atttgctgta cggatgctca agcttttctt ttgatcgtaa atatagacag gctggtcttt
    40981 tcgaatagat cctaatgaat ctttcaaaac agtgtaaggg atgtttcttg cacctaaaat
    41041 atgcccagca tcaaacacat ctttttcgcg aacatcgatt acttgtgctt ttctcattcc
    41101 ttctcgaaat tcttcttctg tcaaagtcgt tgctgaacgc ttggccatta ctcgtagata
    41161 gacttcccaa aagatgattg caagcacaat caatagcaaa atgatattaa ttacccataa
    41221 aaccatgtaa tgcctccgtt tttttaagca aatttcaagg ctaatgaggc agcaccaatg
    41281 acaccagctt cattaccaag ctctgctaat ttgatttttg ttgattctct tacttgcggg
    41341 aaagtaaatt ctttaaaata tttctctaca cggctacgta aaaattctcc tgctgccgat
    41401 actcctccac ctaacacaat acttgacgga ttcaatgtat tccccaagtt ggcgcaagct
    41461 aaacctaagt agaagcatac gcgatcaaca accatcaatg caaacggatc gtcttcttga
    41521 gccatttcaa agatatcttt acttgttact tcttcaccgt tgtctaacat tgctttcagt
    41581 tttgaatctc ctgcgtattc ttctgccaag taacgaccta gacgtaccac accagtagcg
    41641 ctagacacag tttctaaaca tccgcgttta ccgcaagtac attcgaaccc ttcaggatcc
    41701 acagtgatat ggccgatctc tccgcctgct ccgctcacgc cgtgaatcaa atttccgcca
    41761 gcaacgatac caccgccaac acctgttcct agagtaacga atacaacgtc tggatcgttt
    41821 tctccagcac ctttccatcg ttcacctaaa gcagcaacat tcgcatcatt atcgatagcg
    41881 aatttgattc ctgttcctgc ctcgatcagt tttttcacaa attgaacttc tgtccagttt
    41941 aagttatacg caccaataac cgttccagct tcgctgtcca cgcttcctgg ggtacccatg
    42001 ccgattccga taaagtcttc ggctttcata ttatataaat tcaaacgatg gttgattgat
    42061 tcaatgattt caggaacgat atgcttacca tcatccaaaa tattggtatc gatgctccat
    42121 ttttgttgaa tctctccttc tggtgttaaa attgcaaatt ttgctgttgt tccacctaaa
    42181 tcaatcccaa taatcttctt gtccattaca aatttccttt ctttcggctt tcttcaattc
    42241 ggtgctctct ttttaatatg cgccacgctg tcatgtatgt atcatgatca atcaaacggc
    42301 tatcatacag attacgcaat tcgatagtca ttaattcaat gtcatagatg cgtgcaccca
    42361 catagataaa gatgccaaat tttttgaaca gctgctgtac atcatataag ctctccatct
    42421 ttaagcactt ccttcatatt atacaagtaa accatatttt tttaaaccca gtaaaataca
    42481 tattacaaaa agaaatacaa aaactagtgt agaaagaatc ctttggtgta tcgaatagct
    42541 tgtctgttgt ttcggtagac ccaaaacatt ccctaacact aatccgccaa ttagcccacc
    42601 gacatgtccc caaacatcta cagaggtatc cagaagacca aaaacaaatg tcaacacaat
    42661 aaataaaaga aaatgtctga ctagctgctg gatcgctggg ttatgtttaa aatgaaaccc
    42721 taagataaac aacgcaccga acaaaccgaa tatcgaagta ctcgcaccac cagacagaac
    42781 attcgcttcg ttaaaagcaa agcttgctgt atttcccatt atcccgctga acatataaat
    42841 caagaaaaaa cgccaatggc catagattgc ctcgatttgc tgccccataa aatacagtat
    42901 cagtgagttc attacgaaat gcatcagtcc aaaatggatg aagattggtg tcactaaacg
    42961 ccaccattca ttgaagtgaa caagataagg accatacatt ccggcataat aagggatctc
    43021 aagtcgcgga aataattcca tcatgaggaa gaccgctgtc tgtatcccta aaaaagcata
    43081 ggtccataac ggtcgtctta accatgcacg caattttatt tgctgttgat aattcatgaa
    43141 aacctcccat ttcattttag tcaataaaca attgttggat cttctgatca aagctctccg
    43201 gttgccattg ttcattcaat tgttcacgaa aaacaaggct acatgttttt ttatgaaaat
    43261 tatttaaata ccggtcgtaa taaccaccgc caaaaccgat tcgataaccg gctctattgt
    43321 agataatacc tggtacaatg aggagatcga tcatctccgg caaatagagc ttctctgatt
    43381 gtggctcaag aacaccaaaa ctcgaacgta caagaacgga ctgttcatcc atttcataaa
    43441 acgccatctg acgtttcggc aaagttttag gtacaactat tttcttttgt tctttttctg
    43501 ctcgttggat aaccggctgt gtatccagtt caaattcatt cgataaagtc gtccctatca
    43561 cttttgctga cttccagtac tcgctggcga atagctgttt atagattcgc tgttcttttt
    43621 cctttttctt gccacttttg gccagatttt tcagcttttc gattcctttc cggcgtaatc
    43681 ttactttcaa ttggtccaaa aactcaccct tccttctctc ataaaatggt ataggaaaaa
    43741 aagaaaaata gcaatcgaac tttcaaataa atgcataaat agaataaaaa gaagacctag
    43801 aaatgattgg ccttcctttt ttaataaatt tcaactgttc agcgcgtgtt tttgtctgat
    43861 aaaaagtgca tacagaaaat atggcgcacc aaaaagggca atcaaaattc ctgtaggtac
    43921 ttccccactt ggtagaatca ctctagcaac catatctgca ctaagcagaa aaatggaacc
    43981 gaacaaaccg ctcagaacaa aggtccagtt attttcttta cgtacgacta gcttcgcagc
    44041 atgaggagct agtagtccta caaaagataa actacctgtc accgctacac taccgcttgc
    44101 caaagcaaca gctaacaaca aaaggatttt ttgactttta gccacgttaa ggcctaatcc
    44161 ttgcgcgcgt tcttgaccaa atgatagcaa tccaatcctc tgtgcataaa gtcctcctag
    44221 cggaattaag ataaccgccc atggaagcaa tgcccaaaca taaggccagc tcgcacccca
    44281 gattgatccc gctaaccatg cattcacaaa tccataattt tccttagata attggatcgt
    44341 gcatagcaat gttaatgcag aaaggccggc attaacggca ataccggaca ataagattcg
    44401 attcataccc aaaaagccat ttcgatcata ggccgcaaga tagacacagc aagcagctaa
    44461 aacaccacct agaaaggcta caactagcaa tagaaacggc agcgaatagt gcgaaaagaa
    44521 acctaaataa agcatcacta aaaatcctgc tccggcatta atgcccaata tactagaatc
    44581 tgccaattca tttcttgtta ctccttgcaa gatataacca gaaacgccaa gacaagctcc
    44641 tgctaataaa ctgatcagta atcgaggaac tcgaaattct ctaacaatca gcgccaaaga
    44701 agatgattct ttccctatga acgtggcaaa aagctgatcc aggtaaataa aaggcgtacc
    44761 aatcattaaa ctacctatag acaggatgac aagtacaaaa agcaagaaat agaacgtcca
    44821 atatattttt ttcaccgttg ttccctcctt acttgtatca gtaaaaacgg aacgccaatc
    44881 aatgcaatga ctaatccaaa aggtgtttca aaagggggat tgatcatcct cgctgtaaaa
    44941 tccgccaaca taaccaatcc accgccaact aaaaaagaga caggtagaac ataacgatag
    45001 tccgttccaa ccattccgcg aacaactggc ggaaccaaca gcccaataaa tgaaacaggt
    45061 ccgactaacg aaacggcaat ggctgctaac actgcaacta gacagaaaac aatcaaccgc
    45121 gttcgtttag gatgacttcc aagagctaat gcatgtgttt cactcaaatg aatcaaagat
    45181 attgcttttc ctaatgaaaa agaaaccaaa acagcaagta tatataaagg aaacaatact
    45241 gctaattgtt tccatgtgat attggcagct ccgcctacaa accaaaaagc aagatcctgc
    45301 tgcagattaa agaattgggt aagtgcttgg ctgatagcag taaaaaaaga actaatagct
    45361 acgccagcta aaatcagctg taaaggattc atgcccattt tcgaaaactg caaaaaacca
    45421 aatacgagca aagttacagc aaaagaacct gccaatgaca ttagaaacac agaaaaatca
    45481 gaagctttag gccaaaaagc aaaactaagg gccattgcca acgaagcacc cgcgttgatt
    45541 cctagtaagc ctgaatctgc taaaggattt cttgtcactc cttgcatcaa tgcaccgctc
    45601 aatgcaaaac aactccctac aagaaatgct cccgccacac gaggcaaacg aatatttcgt
    45661 atgatttggt gactttgttt tgatctatca aaatcaaaca acgcctgcca aaaatctgct
    45721 tttcccacag tcgctgcgcc atttgaaaga gcaacaaaaa aaataatcaa aagaacaaaa
    45781 cagaccaaaa gcaggagtct atttttcttc atagtcctca taattgatcc tcctgctctt
    45841 ttggcaacaa atcataggtt agaaaaactg gtttatttgt tcttggaagc gtgacaatcg
    45901 ttgcatcaat ctcaaatatt tttttcatac actcttttgt gatcacttct tcaggtgtac
    45961 cttctgtgat caacttaccg tttttcattg ctaataaata atctgaaaaa cgtgaagcat
    46021 gattaatgtc atgaatcgac atcaagatcg ttgtttgttt catttgattg atttcagtca
    46081 ataactgtag gatctctaat tggtgtgccg gatctaaaaa tgttgtcggt tcatccaaga
    46141 tcaagatatc tgtttcctga gcaagcgcca tagcgatcca gacacgctgg gtttgtccac
    46201 cagacagcgt tgcgatatcc cgcatacgaa atccagctag acctgtagca tccaacgccc
    46261 actcgattgc ttcatgatct tgcgtgtcca tgccactgaa cagtttttga taagggtatc
    46321 gtccgtaaga tactacttct tctactgtca tacctgtagg gtgttcacta gtttgtgcta
    46381 ataatgtaat tttttttgca agttcttttg aactgtatgt agagatatca gagttattga
    46441 caatgatctt tcctgatttc acaggtagta tacgggtaaa acttttcaat aaagtagatt
    46501 ttccacttcc atttggccca atcaaactag tgattttccc ttcaggaatc gtaacagaca
    46561 tgttttcaat gatttttttg ttttcgtagc cggctgcaat gtcagctgct cttaatctcg
    46621 tcatttcacc catcctttcg ctgaaaatca ttctcaatta tgacgctgtt tcaacatttc
    46681 gtcaagcgct actttcatat ctatagccaa atgaagcggt tgacagcgtt cgaaatatca
    46741 ggaataataa ccaatgagaa agattctcaa ttatgttagg aggaaagaaa tgaaattaaa
    46801 aacaaaagta ttcacattat ctagcatatt gctgctggct ggagtactga gcgcttgctc
    46861 cccctcttca gataaagaaa cagctacaac tgccaattcg acgacttcat ccaatagtac
    46921 tcatacagtc acagatacac ttggacataa agtagagatt ccaaacgcgc ccaaacggat
    46981 catcggcagt tacttagaag actatctgat tgcactaggg gaaaaaccta tcgcccagtg
    47041 gactgttggc agtggttcca ttcaagatta tctgcaagat gatttaaagg atgtcccaac
    47101 gatttcttat gaccttcctt atgagaaagt gttaagcttt gagcctgatt tgctgttgat
    47161 ttcttcttcc gctactgtcg aaggcgggaa atacgaacaa tatagcaaaa tcgcgccaac
    47221 ttatgttgta aaaaacggaa cagatgtcac atgggaagaa caactaaaag atgtcggcaa
    47281 agctttggca aaagaaaaag aggcagaaaa aatcatttcc gattatcaaa aatccatcaa
    47341 gaaaactcga gaagaactag cagataaaat cgagaacaag acagctgcag tgttgtgggt
    47401 gaccaacaac tcagccttta tggtcagcaa aaatcggtca agtggaagaa tcgtatacga
    47461 cgatctggaa tttggtgttc ctgatctagt ggaagaggtc tccaaaaaag ccacttctga
    47521 ctggtctgct gtttcctctg aaaagctagc tgaattagat gctgactaca tcatccttgt
    47581 gaacagtgac aaagatgctg ccatgttcaa tgaaccaagc tggaagaatc ttaaagcagt
    47641 gacagacaat catgtactgc aattcggacc tgaatctagt tggctatata acggacctat
    47701 tgccagtcag gaaatggtca atgatatcaa agaaaaacta aattgatttt aactaaaaaa
    47761 agaatcttca cgattagtcg tgagatgctt tttttcttat taacaaacta gacgcataga
    47821 ttttattctt cttttgaagc aaccctattt tttactcttt cccatttttg aaaacgatgg
    47881 gcatatagat tttcttgatc cgttatcccc tcatactcct ctataagggc gaagtctgaa
    47941 aaatcaatat tcccaatata cgtatcgcct tcaaacgtgc tatcgatcaa tgttcgccag
    48001 atccgaccag tgtaaggaag aagttcttga aaaatccgac taccacccga aacatagata
    48061 tcttctgaga tcgtttgact atacgacaaa agttcatcga tcgaatgcat tacttccgca
    48121 ttttctttcg tgcgaaaatt tggttgcgtt gtcaacacga tgatatggcg ataaggaagt
    48181 gaaagatccc ccattccttc ataggtcttt cttcccatca ctaaaattcg atccattgta
    48241 tgttcgcgaa agaaacgcat atcatttggc aatcgccatg gtaacaaacc atttttgccg
    48301 atcagaccat ttttatcttg tgcccacatg gaaataaaca tattatccgc tccttatgat
    48361 tttagatgtt ttgagataaa aaaagtctca attctttgac cagcaaggaa ttgagaactt
    48421 taaaaacatt attttgtttc acggtgcaaa gtaactttgc gttcgcgtgg gcaatatttt
    48481 tgtttttcca aacgatcagg attgttacgt ttgtttttgc ttgttagata gttacgttct
    48541 ttacaagaag tacactctaa agtgatgttt acgcgcatgt ttttccctcc catttttaca
    48601 agaatcctct aagatgactc tcagacttga ttatcttacc atgatttttt ctagattgct
    48661 agtgtttttc acgattttgt taagtaaaac tacttgacga taaatacaac ggttttactt
    48721 ctcaaacaaa atctttttct ttttgtataa atacccttac acttgtttat atagattatg
    48781 ttttttaata aagggggata ctaatatgcc atggaacatg aaggactttc ctgcatcaat
    48841 gaaaaactta gataaattga caagaaaaaa agcaatcgac atcgcaaatg cattattaga
    48901 tgaagggtac cctgataacc gtgcgatccc aattgccatt gatcaagcaa aaaaatggta
    48961 tgaagatgct agtgaatcag aaaaacgaac tttcgaaaaa gaaaaaaatc caagcaagac
    49021 ggatgaacac gatacgaatc ctcgtgctgg aaaactgctt gattcagatg tgatcgtaga
    49081 atatgaggaa gaacaatgga tcgtgaaatc taaaggggca aaaaaggcaa gcaaccattt
    49141 tgatacaaaa aaagaagcaa tcgaaaaagg aaagcaagta gcacaaaaca aagaatcaac
    49201 tttgttcatt tataaaaaag atgggacaaa agaaaaagaa atcgattatt gaacatatgt
    49261 aaaggggttg tgacgaaaat cgtgtcacaa cccccttatg ttcgaaacaa tggtgttcct
    49321 ctgccaactc cgaaccataa gtcataatat ctataaaacg ggaagagctg ttttttgaaa
    49381 ttgtttctta tcactcagtg ttaaacggta ggagaaaacc tcttttttat tgatatttga
    49441 ttttcatcaa acagtcacat agtcgattgc ttctgcttgc ggaatcgttt catctacaaa
    49501 gtagacttta taccatgtca agaaactgaa gattgtccag atttttcttt gctcttcttt
    49561 acgtccttcg tgatggtcat ctagcaactt catgattttt tcttgatcaa aaaattcttt
    49621 tgcaaaatct gcttcgaata atgctttgac ttgttcgtag ccgtgttctt ctttcaacca
    49681 agctttgatt ggcacaggga atcctaattt cacacgattc gaccattctt ccggaagatg
    49741 tttgttcgca gcttgtctga aaatatcttt tgtgttgttt tgattcaata aaaacttact
    49801 tggtatttgt tgagccaatt tcatgacttc gatatccaat aaaggtactc ggacttccaa
    49861 agaacttgcc atagaaagtt tatctgcctt taacaagata tcttttggca tccattgatg
    49921 aagatcgaca tattgcatct tattgacttc atctttgatt ccttctgttt tctcgtaatg
    49981 aacagtcatg atttcatcca cagatggtgc tgtttgatat tttggtgtta acacttctga
    50041 tgcttctgat tcttcgaaca ctcgagcatg accgataaaa tattcttttg caggagcaag
    50101 tgattcatat aaatggatcc gtccatggaa atttttcatt tttccgattt tacgtcctaa
    50161 attatagcgt gttccttttg gtaatttttt caatccttga gcaatcacac ggatgaattt
    50221 tgaattcgta tggaatccat acgtttggta tcccgcaaac agttcatccg ccccttctcc
    50281 agattggact acccgcacac tttgtgaagc aagatttgct aaaaagtaca aaggtacgca
    50341 agaaggattt gaatcaggtt catctaagtg atactggatc aaagggaatg ctttgaacga
    50401 catgtctccg tcgatcactg ctgctgtatt atctaagtcc aatagttcgg ttagttttct
    50461 ggcttcaatc gcttcattat aggttttatc atcaaacccg attgagaaag aatgatctgg
    50521 tttcaataca gaggttacat aactggaatc aaccccgctg gataagaaag aaccaacttc
    50581 tacatcactg accgtatgtg cttcaataga agcttgaacg gtttcgtcga ttttttcgat
    50641 ccattcttgt cgggaatgcg tttcttttgt ttcaaaatct gcatcccaat attgctgaat
    50701 gtctagtttt ccatctttat acgtataata atggccttca ggcaaacgat agacatcttt
    50761 gaagaatgtt tcgccgttta atggagaata ttggaaagtc atataaggtt tcaacgcttc
    50821 tttgttcaat tctttgttaa aatcaggatg aggcagaaaa cttttgattt ctgaaccaaa
    50881 cataaatgtt ccgttcattt ctgcataata atatggtttg atcccaaagt ggtctcttgc
    50941 accgaataac tcattctttt cattatccca aatagcaaaa gcaaacattc cgcggatctt
    51001 ttgcaataat tctgttcccc attcttcgta accatgcaaa aggacttctg tatctgcatg
    51061 tgtttgaaaa acgtggccag ctgcaatcaa ttcttctctc aaaggctggt aattatagat
    51121 ttcgccatta aaaataatga tctttgtccg atcttcattg taaataggct gagtaccgcc
    51181 ctctaagtca ataatactta atcttctgaa tcctaaagca acatgtttat cgatatattc
    51241 tcctgaacta ttaggtccac ggtgaacgat tcgatccatc attgtattaa taattgtttt
    51301 tttgttgtcc ttgtcgttaa caaaacctac aataccgcac atttaacttt cacatcctaa
    51361 tataaaatta ctgtttattt cattcatatg catcttatca tagaataaat agcggacgaa
    51421 tattttctct cttacaattt cgtcacgtga aaacaaaaga tgaaagtttc tgtttttaca
    51481 gaaaataaag tcccaatatc taatttacca tgttttcttt tttgaggcta ccttattctc
    51541 ttcgtgttaa aaaaatatta gtggatgcta tttccaaaaa aaacagcaaa aaaagacacg
    51601 acctaaagat cgtgtctaat tatgactgta tcagaaaata tgataccaaa cggatctatt
    51661 cattaattaa ttgacatagt ttatctgttg ctcttttatg actggataac tgaccaattc
    51721 atgacgatcc aagtcttctt tatttatatt tacagcagta atttgactgt cttcatacgt
    51781 acgataataa taaatccctt tatcaacgtt acagcaagaa gaataaatcg tatattcgta
    51841 ttttccttct ccagtatcgc atactccttt ttgttgctcg actgagccta gtatatgaaa
    51901 aaattgactg atactttcag attctgaatc acctgatgca gcattcattt tagtaaatgt
    51961 ggcttttaca aatcgagaaa cagaagagag atctccaggt aagcccaatc ctcccatccc
    52021 acgactataa acattcaagc tgatctggtt tgaaaaatga ttttctggtg ttccatttga
    52081 tagcgagcga taattgttca gattaaataa ttgataatca aatggcggat tatttgtcaa
    52141 cacaccgaca ggattatcat ataaatgaag tccatctttc atactttcaa ttactatcga
    52201 tttttcttta tcagctaata accagtgtaa aggtgacaag ggtagttttt cactaaaatc
    52261 gatattgact agattgatag tagccaataa ttctttagct tcgtctatgg ttgagcattg
    52321 ccctagtatc catggaataa actcaaatgg tgcaacgtta tcttttcctt cttgtaattc
    52381 tttataatca gcattgccag gaaaattcag tcctgccata ctcaaccctt tttcatttgt
    52441 agcctcataa tagagtggat agttggatac cccagctgct attcctatca ttgcataatg
    52501 tttatctaaa ttttttacct ttctaaaatc gaaacgataa tttcttggag taatagtgac
    52561 tacttcatta taagacatct cataatcaaa attccttcca aaataatggt ctttcgttgc
    52621 ataagtgatt gcggtacaca tcgttttccc tcctaaaaca aatcgttttt acacttttat
    52681 cttacatcta gtattttttt ttatcaaaaa aaaggccaaa gaagattgat ttactagcat
    52741 ttataaaaaa tagtactcag ggggaatcaa aaaatattgt aggttaaaag tacaacaata
    52801 aggggctgtg acaaaagtct tgtcacagcc ccttattccg aacaaacggt gttcaaaagc
    52861 ttgcatctgc ggtaataagc ccaaccaaac gaaaaaatag gaaaagctat ttttgtttgg
    52921 ccgttcttat tacttgatgc aggacagctt cttcacaacc tctaatcgtt gatataagga
    52981 aggtacagga tttgaacctg cgcgccggta ttagccggtt cgccggattt cgagtccggt
    53041 gcattaccac tctgccaacc ttccgtaagt actattttta aacttttttc acgaaatgtc
    53101 aagcctattt ctaatagata aataacagaa atcgcttttt ttagcaaaaa agtccattga
    53161 cagtttgcag ccaacggact taccgatcaa attcatactg atagaacact atctgattat
    53221 ttcaggatta tctaatgcta aaatcgagtc aattgtccgt ttgatcagtg caatgatttg
    53281 ttcttctgtt ggatgcatga tgtttgatga catcaatgac gctaagccag tcactgctac
    53341 ccatgtacca gtatgcagag catcgacata ttcatccgat aattgattgt atctttcatc
    53401 ttctttaact atttcacgga aataattgta tgaaaaatca tgcattttct ttccgtcccc
    53461 atgttcatca atgtacaatg ccatgtaaag actatgatgc ttttttgcaa agtagatata
    53521 gttcaaaccg agatcaatga ttttatcacc agtacgttca atagggaaaa catcttcttt
    53581 tagttgttca aagatagaat ccagcaacgt attttttaaa tcttccatgt ttttgaattc
    53641 cagataaatc ggctgtgtcg aaatccccat ctttttagca atatttctcg cagtaaatcc
    53701 tttaaaccct tcctttgcaa caacatcata agcagctttt agaatttgat ccttggtata
    53761 gacttttctt ctcattaaaa ctcccccact tctttactgc agtatatgtt gttttattgt
    53821 accctatttt tagcattttt tgcaaacatt ttactcaaaa cgttatattt taaatttttt
    53881 tcagtcttct ttaacttttt tttgcaaaat taaaaaaatt tggttaaatt caatgggttc
    53941 ccttacattt ttagttttga cctaaatgat agttgtccaa atctttcatt tcaagttata
    54001 gttaaagaaa atgaaaaaga aggtgtgtaa tggaaaacga aactgacgtt atttatattc
    54061 atcctcaaaa acgaatcgtt tcacagaaaa gaaagtattt ttatcttggt tttacaggtg
    54121 ttttttttct ttttattggc ttgctttcta atactcctac tgataattgg agtggattgc
    54181 taactattct tacctcgcca agcaatcttt tgacagatta ttttgcttta ggtgttttcg
    54241 gaagcgcatt cataaatgta gggattttga ccttactttc tgtgctttta gcttatcggc
    54301 acaaggtgat tttaaacggt cccttatttg cttcgattct aacagttacc ggtttctctt
    54361 tttttggcaa aaacctttat aattctatct caatcatttt aggtgtgtat ctatacgctg
    54421 tatttgtcaa taaacctttt tctcagtaca tcatgatcgg actgtttggt agcgtattat
    54481 caccggtcgt tagttatatc acttttggta tgcgttttcc tttactgata ggtattttat
    54541 tggggaattt agctggcata gcaattggta tacttcttcc gcccttagct gctcaaactt
    54601 tagttttcca tcgtggattc acactttata atattggatt cacctctggg ttgattgcga
    54661 tgacttttac tgctgttttg aggttattca gctattcaat cgtcgaaaat acattggttt
    54721 tcaatgaata tcactttcct ctcatttgga ttatttttgg ctttttttcg ctgacagtcg
    54781 gaattggttt ctattataat tcctttcggc tttcggggat tcgagaaatt ttcgattcat
    54841 ctggaaaatt gacaactgat ttcattgcta attctggtat tggtgctact ttgatcaaca
    54901 tgggcttagt tggtctgatg ctgtcttctt atgttttgct ggttggcggt cagttaaatg
    54961 gacctgtcat cggtgctatt ttatctgcgg tgggtttcag tgcttctggt tgtcatttaa
    55021 aaaacagttt tccgatacta gtcggaatat ttattgcttc tttgtttgga acttttcatg
    55081 agatcaccag tactggcatg cttgttgcag ctgtgtttgg gacaggtctt gcgcccataa
    55141 gcggttttta cggcagtttt tacggtgtaa tagctggtgt gctacatatt gctcttgtcc
    55201 ataacgtcag cactttgcac ggaggactaa atctatataa cagtggtttt tcaactggtt
    55261 tcgttgcagg tatccttgta ccgatactag ataactttac cgctgtcaga aaggaaaaaa
    55321 agacacttgg aaaaagaatt atcaaaaaga atcatcgatg agcttcttac ttatttatat
    55381 tcccatgaaa taactgaaat acgtattgga gtagaatttg ctgaggaagg gcttttcata
    55441 gagatacagg gtacggcaga aactcagcca gaagatttag atgtacttgc tgatttgctg
    55501 aacaatcctc gggaccctag tatggaaatc tactatcaag aactattagg taatccccga
    55561 catgatcggg aagattatca tctgttaggt agtttgattg atgacgtgga aatcatgtat
    55621 gcccagccga ttatcaatat taagatcttt cgacgtgctt ctcattccta ttattaaccc
    55681 tattttctat ttataaaaga ctgaatcaaa aaagcagctc ctgaaagttc gattaaaatc
    55741 tactttcagg agctgttcaa gcttgacatt attgattttc caatccttca tacacttcat
    55801 ctgttacagg ttctaaaaac tctgaattac cagcagtgat cgccaaatgt tcaaaccaac
    55861 tgtcttttgt cgcaccatgc caatgtttaa tccctttgtg cgttacgacg acatctccag
    55921 ccattaatcg tcttgctggc tttccttctt cctgatacca gccttctcct ccggtcacaa
    55981 gtaagatttg atagccgtct gtatggacat gccagtgatt gcgacaacct ggttcaaaag
    56041 ttacattacc tacaccaaca gaaacttcgg gatcattcac taacatattc agatagcttt
    56101 gcccggtaaa tacttgagcg taagcttcgt ttttttcacc tgctggaaaa atcacgccat
    56161 tgtgtatttc ttcgtgtttt gtcatcattt acgcctcttt cttatcttcg ctattttctt
    56221 ctaaatagat ttcttttgct aaactaaaag ctgaccaagc ttttggccat tctacataaa
    56281 aagctaaatg ggtaatgatt tctgctattt cttcactagt aatgccattt tgcttgccaa
    56341 tcttcagatg agctggcaat tgttcaaaat ttcctcctga aattaatgca gatatggtga
    56401 tgatactacg ctgatgagca gataattctt ctctggacca tacttgtcca aataaaacat
    56461 catcatttaa ttctgcaaat tttggtgcaa aatctcctaa ttgatctcgt cctgcggttt
    56521 gtttttctgc catttctctt attctccctt cacgactgtt aggtgattca actatggttc
    56581 taaggcaact ttattttcta ttgtttcttc gcatttcatt ttaaatgtag tctttcagcc
    56641 tgtccaatgc ttagtttatt cagtcgatat gctttttaag catagttgct aacgcttttt
    56701 ttattttaaa aaaaacaagt tattaaataa gtctttagtt ggatgttttt ttgagatcaa
    56761 tcttttatac ttatgatgaa cttacaaaat tgtttgtttt ctgtcatatc aaaaaatggc
    56821 gcagttagtt gcttttctag taaagtatag ttaacaaaga acctctaagg agttgatgaa
    56881 taatgaatat tgctgcctct cgaaaactga taaatttcat atccattatc ggattaggcc
    56941 tatcaatcgc gctgacgatt tattttatta atttaggtgt tttcaaagat ttgaatgcgt
    57001 taagaggatt agtaggtgat tccatcattt taggaccgat tatttttgtc ttcatccaaa
    57061 tcctgcaagt agttattcca atcattcctg gagggatcag tactgcagct ggtgtcctga
    57121 tatttggccc ttatgctgga tttatctata actatattgg aatctgcatt ggttcgatta
    57181 tcatttttct gctagggcgt cgttatggaa agccattcat actttccatg attagcgata
    57241 agacatataa caaatatatt ggctggctgg ataatcaaaa ccgttttgag aagctgtttg
    57301 ctctagctat ttttcttcca gttgctcctg acgatgcgtt atgtttgatg gctggattga
    57361 caaacatgtc agtgaaacga tatacactaa tcattttgat tgctaaacca ctgtcgattt
    57421 tcttatatag tatggccttg atttatggag gtcaatatct aagtggtctt cttggataat
    57481 atttattttg taaaattagt cattgattga caatgt
//
LOCUS       DAZULR010000014        57072 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.014, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000014 DAZULR010000000
VERSION     DAZULR010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 57072)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57072)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57072
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.014"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            591..1280
                     /locus_tag="ACG8ZV_000970"
     CDS             591..1280
                     /locus_tag="ACG8ZV_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFS4996326.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1267..2475
                     /locus_tag="ACG8ZV_000971"
     CDS             1267..2475
                     /locus_tag="ACG8ZV_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFS4996327.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2769..4040
                     /gene="serS"
                     /locus_tag="ACG8ZV_000972"
     CDS             2769..4040
                     /gene="serS"
                     /locus_tag="ACG8ZV_000972"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HFS4996328.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="ACG8ZV_000973"
     CDS             complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="ACG8ZV_000973"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HFS4996329.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6578..7273)
                     /locus_tag="ACG8ZV_000974"
     CDS             complement(6578..7273)
                     /locus_tag="ACG8ZV_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HFS4996330.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="ACG8ZV_000975"
     CDS             complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="ACG8ZV_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HFS4996331.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8472..8663)
                     /locus_tag="ACG8ZV_000976"
     CDS             complement(8472..8663)
                     /locus_tag="ACG8ZV_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HFS4996332.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8684..9574)
                     /locus_tag="ACG8ZV_000977"
     CDS             complement(8684..9574)
                     /locus_tag="ACG8ZV_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HFS4996333.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9561..10328)
                     /locus_tag="ACG8ZV_000978"
     CDS             complement(9561..10328)
                     /locus_tag="ACG8ZV_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFS4996334.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="ACG8ZV_000979"
     CDS             complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="ACG8ZV_000979"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HFS4996335.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="ACG8ZV_000980"
     CDS             complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="ACG8ZV_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HFS4996336.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="ACG8ZV_000981"
     CDS             complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="ACG8ZV_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HFS4996337.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14899..15282
                     /locus_tag="ACG8ZV_000982"
     CDS             14899..15282
                     /locus_tag="ACG8ZV_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996338.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15450..16208)
                     /gene="jag"
                     /locus_tag="ACG8ZV_000983"
     CDS             complement(15450..16208)
                     /gene="jag"
                     /locus_tag="ACG8ZV_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HFS4996339.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16226..17044)
                     /locus_tag="ACG8ZV_000984"
     CDS             complement(16226..17044)
                     /locus_tag="ACG8ZV_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0032977 - membrane insertase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YidC/Oxa1 family membrane protein insertase"
                     /protein_id="HFS4996340.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="ACG8ZV_000985"
     CDS             complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="ACG8ZV_000985"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HFS4996341.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="ACG8ZV_000986"
     CDS             complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="ACG8ZV_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HFS4996342.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18172..19506
                     /gene="dnaA"
                     /locus_tag="ACG8ZV_000987"
     CDS             18172..19506
                     /gene="dnaA"
                     /locus_tag="ACG8ZV_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HFS4996343.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19704..20834
                     /gene="dnaN"
                     /locus_tag="ACG8ZV_000988"
     CDS             19704..20834
                     /gene="dnaN"
                     /locus_tag="ACG8ZV_000988"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HFS4996344.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21063..21305
                     /gene="yaaA"
                     /locus_tag="ACG8ZV_000989"
     CDS             21063..21305
                     /gene="yaaA"
                     /locus_tag="ACG8ZV_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HFS4996345.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21292..22416
                     /gene="recF"
                     /locus_tag="ACG8ZV_000990"
     CDS             21292..22416
                     /gene="recF"
                     /locus_tag="ACG8ZV_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HFS4996346.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22413..24359
                     /gene="gyrB"
                     /locus_tag="ACG8ZV_000991"
     CDS             22413..24359
                     /gene="gyrB"
                     /locus_tag="ACG8ZV_000991"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HFS4996347.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24379..26850
                     /gene="gyrA"
                     /locus_tag="ACG8ZV_000992"
     CDS             24379..26850
                     /gene="gyrA"
                     /locus_tag="ACG8ZV_000992"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HFS4996348.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDIAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKENQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27086..27385
                     /gene="rpsF"
                     /locus_tag="ACG8ZV_000993"
     CDS             27086..27385
                     /gene="rpsF"
                     /locus_tag="ACG8ZV_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HFS4996349.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27435..27947
                     /gene="ssb"
                     /locus_tag="ACG8ZV_000994"
     CDS             27435..27947
                     /gene="ssb"
                     /locus_tag="ACG8ZV_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFS4996350.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27973..28209
                     /gene="rpsR"
                     /locus_tag="ACG8ZV_000995"
     CDS             27973..28209
                     /gene="rpsR"
                     /locus_tag="ACG8ZV_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HFS4996351.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28352..30325
                     /locus_tag="ACG8ZV_000996"
     CDS             28352..30325
                     /locus_tag="ACG8ZV_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HFS4996352.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30331..30783
                     /gene="rplI"
                     /locus_tag="ACG8ZV_000997"
     CDS             30331..30783
                     /gene="rplI"
                     /locus_tag="ACG8ZV_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HFS4996353.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31057..32424
                     /gene="dnaB"
                     /locus_tag="ACG8ZV_000998"
     CDS             31057..32424
                     /gene="dnaB"
                     /locus_tag="ACG8ZV_000998"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HFS4996354.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33204..34496
                     /locus_tag="ACG8ZV_000999"
     CDS             33204..34496
                     /locus_tag="ACG8ZV_000999"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HFS4996355.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
     gene            35283..36146
                     /locus_tag="ACG8ZV_001000"
     CDS             35283..36146
                     /locus_tag="ACG8ZV_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFS4996356.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(36275..37897)
                     /locus_tag="ACG8ZV_001001"
     CDS             complement(36275..37897)
                     /locus_tag="ACG8ZV_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFS4996357.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            38146..38667
                     /locus_tag="ACG8ZV_001002"
     CDS             38146..38667
                     /locus_tag="ACG8ZV_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HFS4996358.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(38853..40583)
                     /gene="spxB"
                     /locus_tag="ACG8ZV_001003"
     CDS             complement(38853..40583)
                     /gene="spxB"
                     /locus_tag="ACG8ZV_001003"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047112 - pyruvate oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HFS4996359.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            40748..41566
                     /locus_tag="ACG8ZV_001004"
     CDS             40748..41566
                     /locus_tag="ACG8ZV_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HFS4996360.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(41669..41866)
                     /locus_tag="ACG8ZV_001005"
     CDS             complement(41669..41866)
                     /locus_tag="ACG8ZV_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996361.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            42035..42613
                     /locus_tag="ACG8ZV_001006"
     CDS             42035..42613
                     /locus_tag="ACG8ZV_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HFS4996362.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            42708..42845
                     /locus_tag="ACG8ZV_001007"
     CDS             42708..42845
                     /locus_tag="ACG8ZV_001007"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996363.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(43658..44161)
                     /locus_tag="ACG8ZV_001008"
     CDS             complement(43658..44161)
                     /locus_tag="ACG8ZV_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFS4996364.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            44520..45545
                     /locus_tag="ACG8ZV_001009"
     CDS             44520..45545
                     /locus_tag="ACG8ZV_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFS4996365.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            45868..46746
                     /locus_tag="ACG8ZV_001010"
     CDS             45868..46746
                     /locus_tag="ACG8ZV_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase domain-containing protein"
                     /protein_id="HFS4996366.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            47222..47338
                     /locus_tag="ACG8ZV_001011"
     CDS             47222..47338
                     /locus_tag="ACG8ZV_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HFS4996367.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            48266..48604
                     /locus_tag="ACG8ZV_001012"
     CDS             48266..48604
                     /locus_tag="ACG8ZV_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996368.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            48698..48928
                     /locus_tag="ACG8ZV_001013"
     CDS             48698..48928
                     /locus_tag="ACG8ZV_001013"
                     /inference="COORDINATES: protein motif:HMM:NF042636.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6568 family protein"
                     /protein_id="HFS4996369.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            49328..49699
                     /locus_tag="ACG8ZV_001014"
     CDS             49328..49699
                     /locus_tag="ACG8ZV_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HFS4996370.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(49973..50665)
                     /locus_tag="ACG8ZV_001015"
     CDS             complement(49973..50665)
                     /locus_tag="ACG8ZV_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFS4996371.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(50668..51453)
                     /locus_tag="ACG8ZV_001016"
     CDS             complement(50668..51453)
                     /locus_tag="ACG8ZV_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFS4996372.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            51690..53090
                     /gene="lacG"
                     /locus_tag="ACG8ZV_001017"
     CDS             51690..53090
                     /gene="lacG"
                     /locus_tag="ACG8ZV_001017"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HFS4996373.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            53115..53432
                     /locus_tag="ACG8ZV_001018"
     CDS             53115..53432
                     /locus_tag="ACG8ZV_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFS4996374.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            53445..55118
                     /locus_tag="ACG8ZV_001019"
     CDS             53445..55118
                     /locus_tag="ACG8ZV_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HFS4996375.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            55132..56763
                     /locus_tag="ACG8ZV_001020"
     CDS             55132..56763
                     /locus_tag="ACG8ZV_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinogalactan endo-beta-1,4-galactanase"
                     /protein_id="HFS4996376.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
BASE COUNT        17533 a        10527 c        11381 g        17631 t
ORIGIN      
        1 ggagtgtttc ccgattcgtt tttggctgcc gtagcaactt ttatatcata tcagagagac
       61 aagtaattgt caactctttt ttaaaagttt tttcgatttc gtttttcgaa atcttccagc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcat
      241 ttccaacatg tcaacaactt attttttatt atttaataag ttattggtgt tcttttgaac
      301 aaataataat atatcaacat cacatgtgaa agtcaataag aaaatgctta tttatcaaca
      361 tttctagctt acatgatcat tggttagttc tggtcctttt tcgttcgtct ttataactcc
      421 gagagacgta aaatcctttt gttttcagtt taatgttcat gttcttgtct tattcacacc
      481 aactagatgt ctcaccttct aaaattttcc ttaacaaagt gctgctttta tctatttctg
      541 cttttttttg ctagaataat agtaacaata tgactctgga ggatttattt atgaaaattt
      601 tgattgctga cgatgataaa gaaatcgttg aattattaag tatctatgtt cacaatgagg
      661 ggtatgaagc agtaaaggct tatgatggga aagaagcatt atctaaaatc agaacaatcc
      721 ctgatattga attacttatt ttagatatca tgatgcctga gatggatggg atgcaagtag
      781 tgaaagagct acgaaaagaa tcccaaatac caatcattat gctgacagca aaaactactg
      841 atatggataa gatcaaagga ctggtcgctg gtgcagatga ttatgtgacc aagccattta
      901 atccgttaga agtaatggct agagtaaagt ctttattacg gcgtacaaaa atgcagattg
      961 ccccagatca gcctgatgta ttagaagtaa atgcattaat catcaataaa gactctcatg
     1021 aagttaaaac aatcgatggg aaagaaatcc agttaacagc tttggaattc ggtatcctct
     1081 acttgcttgc tagtcatcct aatcgagtat ttagcgcgga tgaaattttt gagcgtgttt
     1141 ggaaacaaga aagtattgtc tctgctaaaa ctgtcatggt tcacgttagt catttaagag
     1201 ataagattga agaagcaact ggtggtgaaa aagtcattca aaccgtttgg ggagtgggct
     1261 ataaaattga cgcaagatag taaacgagca actgaaaaac gccgtcggat caatttgact
     1321 tcaaaagaaa tcagcgaatt gttagcggaa ggaatcatca cgattatcct tttgcttcta
     1381 ttaaatgttt ctattctggt tgttatcagt tcggtgatca acagttcacc ttctttgacg
     1441 aatgcgattt gggattcaaa gaatattttt gcagaacgat tgaacactga tttgttctgg
     1501 aacggccgga attttattat tccctttttc tttctattag atattggtgt tttgtattgg
     1561 cgcttgattc gaagatatcg ccaaatgcaa ttgcggcata tcatcagcga acttcactac
     1621 atcgcaaacg gaaattatga tcatcgtatc ccttttgaac tgagtggtga cttaagccga
     1681 gtggtaacaa gtatcaatgg attggtggat agtaccgtag cagcgattga agacgaacgt
     1741 aaaatcgaaa aatcaaaaga tgaattgatc acgaatgtca gtcatgatat ccgtacccca
     1801 ctcacgtcca tcattggata cctaggactg atagaagatg gccagtatca ctcagaagaa
     1861 gatcttttaa agtatacgca tactgcttat atcaaagcaa agcagatgaa atctttagtg
     1921 gacgacttat ttgaatacac taaggtacgc cagcctgctg tcccggtgaa tttttctgcc
     1981 tttgacatga tccagttgat cgaacagtta gcagctgatt ttgagttgga agcttctaaa
     2041 aaaaatatcc aaatacttgt tcaatcaaaa gtagactccc ttatcatgga tggcgatacc
     2101 gaaaaacttg tacgtgtctt caataatctt ttgacgaatg cgttgaaata cggaaaagga
     2161 gcaacgaaga tcgtaatcga agtagaacgt atcggttcag aagttgttgc aacagtcaaa
     2221 aataacggag caatgatccc acaacaggca atcgataatc tattcgaccg tttttatcgt
     2281 gtagaagaat ctcgttcaca agcaactgga ggaactggac ttggtttagc aatcgctcaa
     2341 agcattgtgg ctttgcacgg cggatacatt tatgcaaaat cagataagca atggacttct
     2401 ttcatcatgc accttccaat caagaaaaat gaaaaattac ctattgatac acaggaagtt
     2461 attgacgaaa gctgaaatat tcgctattct tattacaatt attagaataa atgaaaaaca
     2521 cagaacccag tacactttat tctttttcag agagctgatg gcaggtgtaa atcagcaaag
     2581 gataatttgg aagttccagt tcgtttacgt gccctttcga aataagaaag gtcggttcaa
     2641 cagccgttat gtgttcaaca agtgcagctg acgctgaact tgggtggtac cgcgaatttc
     2701 agactgattc gtcccaagaa taatgggatg gatcagtctt tttttatttt caaaaaggag
     2761 gaaatcatat gttagatgta aaaatgatgc gacaaaatat tgaagaagta caagaaaaat
     2821 tgatgactcg gggcgtaaaa aaagaaacat tagctgaatt catggaacta gatgaaaatc
     2881 gtcgtaagct actagtcaaa agtgaagaat taaaaaaata tcgaaatgat gtttctgctg
     2941 agatcgccca attgaagcgt gcaaaagaag atgcttctgc taaaatcgct gaaatgaaag
     3001 aagtcggtgg caacatcaaa gcattggata ctgaaattgc tgaagtggat gaaaaattga
     3061 aacaaattgc aactactttg ccaaaccttc cccatgattc tgtgccagtt ggaacagatg
     3121 aagaggacaa tgtagaaatc cgtcgttgga gcgaaccacg tacatttgct tttgaaccaa
     3181 aaccacactg ggaaattgca gaaaatcttg atattttaga ttttgaacgt ggcgcaaaag
     3241 tagccggtag ccgttttgtc tattacaaag gattaggtgc tcgattagaa cgtgctgtct
     3301 acaacttcat gcttgatcag catatttacg aacacggcta tactgaaatg atcactcctt
     3361 atatcgtcaa cagtaaagcg atgtttggta cgggacaatt tccaaaattc aaagaagatg
     3421 ttttccaatt ggagaatact gatctaacat taatcccaac agctgaagta ccattaacta
     3481 actattataa tgatgaaatt ttagatggtg cagatttacc tatttatttc actgcactaa
     3541 gccctgcttt tcgttctgaa gccggaagtg ctggtcggga tacacgagga ctgattcgtc
     3601 ttcaccaatt caataaagta gaaatggtca aattttcgga tgtagagcat tcttacgaag
     3661 aattggaaaa aatgacagct gatgcagaag atatcttgaa aaaattgcat ttgccttatc
     3721 gtgtgatggc cttatcaact ggagacatgg gcttttctgc agctaaaact tatgacttag
     3781 aagtatggat acctgcacaa gatacttatc gtgaaatcag ttcttgttct aactgtgaag
     3841 atttccaagc acgccgcgca atgatccgtt atcgcgataa tgatggaaaa atccactata
     3901 ctcatactct gaatggttca ggacttgcag ttggccgtac agtagctgcc attttggaaa
     3961 actaccaaaa tgaagatggt tctgtcacag ttccagaagc gctcgttcct tatatgggga
     4021 atctgaaagt tattaaataa agaggctgtg aaaaagccgc ttagtttcga gtattaagaa
     4081 aaattttgtg aaaatggctt tccacatttt tgcataaatt ggacttaata ccgagaaact
     4141 ggcttttgaa caccatttat cgagaggttg tgaaatcagc gaattaacct gagtattaga
     4201 gaaaaaaatg gaaaaatagt ccctcatatt ttaccgtttg ttgaactaat accgagggtc
     4261 agctgattga acaccgttta gtggagaggt cgtaagccta ccccccagct cctagttaca
     4321 aggacaaatt caaaaaacag ctcttcatat tttatgaatg ttgtacttgt gattcggagg
     4381 tggcaaggga acactgttta ttcaaaaaga ggctgggaca gaagcgttta actccaagaa
     4441 ataagaagaa attcacgaaa attgcttttc aaatttttgt gaatttcttc ttatttccga
     4501 aggagttgct tctacttccg ccgtttatac gtgtttagag cgtgagacaa aagtgttctt
     4561 tacttttgtc ccacgctctt taatgttttt aagattcaac tgaatagttt ggtgcttctt
     4621 ttgtgatttg tacatcatga gggtgtgatt cttttaatcc actgccgctc atttggataa
     4681 attgcgcttc atcacgtaat tgctgtagat tggctgcccc aacataaccc attcctgaac
     4741 gcaaaccgcc gatcatttgg aaaataatat ctgcaacact tcctttataa gcaacccgac
     4801 cttcgattcc ttctggtact aatttatttg cttcattgac actaccttgg aagtaacggt
     4861 cttttgaacc tttttccatc gcgcctaatg agcccatacc tcggtatgtt ttgaatcgac
     4921 gtccttggaa gatttcgaat tcacctggtg attcatctgt ccctgccaac atacttccta
     4981 gcatcactgc atgtccgccg gcagctaatg ctttgacgat gtcaccagaa tatttgatcc
     5041 ctccgtctgc aataatcgct ttgccatatt gacgagcaac tgatgctgca tcataaatag
     5101 ctgtgagctg aggtacacct acaccggcta ccacacgtgt cgtacaaatc gatcctggtc
     5161 cgataccaac ttttacgaca tctacacctg catcatataa agcttttgtc gcttcagccg
     5221 tcgcaacgtt tcctgcaatc aatgttgcat ctgcaaaagt tgaacggatt tcttgaattt
     5281 ttcggatcac acctgcacta tgtccatgag ctgtatcgat gatgattgca tctgcccctg
     5341 cttctaataa agcattcgca cgctcaaatg tatcgcttgt tacaccaacg gctgctgcta
     5401 caagcaatcg accatgttca tcttttgctg catttggaaa ttcgatcact ttctcgatgt
     5461 ctttgatcgt gatcaatccg cttaaacgac cttcgttatc tacgattggt aatttttcga
     5521 ttttatgttt ttgcaaaatc ttttctgcat cttttagaga ggtacctact ggggcagtca
     5581 ctaagttgtc ttttgtcatc acatcagcaa tcggcatgtg ataatctgtt acaaaacgca
     5641 tgtcgcggtt tgtaattatc cctaccaatt ttctgttttc aagtgtttca acgattggca
     5701 caccactgat acgatatttg ctcatcaatt cttctgcgtc tgctacaaga tgctgtggcg
     5761 ttaagaagaa cggatcaatg attacgccac tttcagaacg tttgactttt cttacttcat
     5821 ccgcttgctg gctgatcgtc atgtttttat ggatcacacc tagtccgcct tgtcttgcca
     5881 tagcaatggc catcttgctg tcggtaacag tatccatact tgcactgatg attggaatat
     5941 tcaacttaat atttttagct aattgtacgc tcatatccac ttcgtttggt aacacgtgac
     6001 tttctgctgg tatcaataag acatcatcaa aagtaaatcc ttttttcgtg aactttgttt
     6061 cccagttgga catttttagt accactcctc taatttagtt tatctattaa aataattgat
     6121 tttttcattt aagtcaatga tctacttgga atcaagttag ctttctcata gaataccaat
     6181 ataaagcgtt tacatctgtg tgtattaaaa gagattgtaa aaaagctgtc ctgcatcaag
     6241 taataagaac agccaatcaa aaacagcttc tcatgttttt gaattggttg ggtttattac
     6301 cgcagatgca aacttttgaa caccgtttag tggagaggct gtgaaaaagc tgcttagttt
     6361 cgagtagtaa gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa attggactta
     6421 ataccgagaa actggctttt gaacaccgtt tatcgtaaaa agggactgtg acaagacttt
     6481 tgtcacagtc ccttactatt atttaactat ggataaacaa aatgaggttc tttactaccc
     6541 ctagatatct agcaaaatag ctgatctttt tgctagttta tcttcttggg acggataaac
     6601 ttccaataat cccgtatttt ttcttcaagt agtaacggat tgctaaagca gttgccccga
     6661 taatgataac tactactgga tctaatactg gattgataac tggtggcaat agtgttgtcg
     6721 cagaaaacag tacgacccaa agaagtgtcg ttccacctag gataagcaat gtcttaccca
     6781 ttcctggttt cttgcttcga tctgctccgg gatattcata ttgatagatg tatttgtaca
     6841 tcatataaaa gacccagcca ccgattgcag aacctagaac gagtgtagaa aagccataag
     6901 ctggcgttgt tccacgtgaa aacaatccgg taatcgcaat catgatactt aatagaccaa
     6961 gcaacagcaa cgtattatct aaccacatca ataaaggggt ggatgaattt tttacttctg
     7021 ctggcttatt gatgattgct tccgttcttt cagagactgt cccaaacaat tgacgggctg
     7081 ttcttccgcc tttttgttct gcaactaaag taggcagaat gtcatgaagg gcttttactt
     7141 tttcttcttc agacaaattc gctgcttcta aagatttttt caaatcaaaa atgtactgtt
     7201 gatttctttt ggttaatttt gtttctaaac tattgttttc ttttacgatt gctcgtaatt
     7261 gttctggttc cattatctaa tagtcctcct tagccgttcc ttttctcaac ggtcgtcaca
     7321 aaagacattc taccatattc tacagctagt ttgatagccc ttttacacat taaagcggaa
     7381 taacattacg tcgccgtctt gtacgacata atcttttcct tctaatcgaa cacgtccagc
     7441 ttcttttgct gcatgcatgt ttccgtaatg atccaagtct tcaaaagaga cagtttctgc
     7501 acggataaat ccgcgttcga aatctgaatg gatgattcct gctgcttgtg gtgctttgat
     7561 tccttttttg aatgtccaag cacgtacttc ttgttcccca gcagtaaagt aagtagctaa
     7621 gcctaacaaa tcataagcag cacggatcaa ctgatccaaa cctgattctt cgattcctaa
     7681 agcttctaaa aattccgctt tgtcttcttc atctaattct gcgatttctt cttctgcacg
     7741 agcactgacc acgatcactt ctgcattttc ttctgcagca aagttgcgca cttcttgtac
     7801 ataatgattc gcgtctgcat ctgctacgtc atcttctgag acattggcta cataaagaat
     7861 tggttttgtc gtcaataaaa atagtgattt aacgattttt tgttcttctt cagtaaattc
     7921 gatcgttcgg gcagattttc cttcttccag tacaggtttg attttatcca gtacagctag
     7981 ttctgccact gcatctttat ctttggtttt agcaactttt gctacacgag tatagcgttt
     8041 gttgatagat tctaagtctg ctaacactag ttccaagttg atcgtatcaa tatcttctag
     8101 tggatcaaca cgtccttcta cgtgagtaat attatcatca tcaaaacagc gaacaacgtg
     8161 acaaatagcg tctacttggc ggatatggct taagaattga tttcccaaac cttctccttt
     8221 acttgcgcct tttacgattc cagcaatatc tgtaaattca aaagtcgtcg gaacagtttt
     8281 tttcggatgt acaagttctg ttaagcgttg caaacgccag tcaggtactt ctaccatccc
     8341 tacgttgggg tcgatcgtcg caaagggata gtttgctgct tctgctcctg cttttgtgat
     8401 cgcattaaac aaagttgatt ttcctacgtt gggcaaccca acaattccag cagtcaatgc
     8461 cataaattta ttcactcttt ctctgcattt ttttcaatta ctttttttaa tttcttttca
     8521 aaatctcgac gggtcatcat gacgatatgt ccgcaattca tacatctgat tttgatatct
     8581 gcgcccattc gaatgacttc ccagcgattc gtctggcaag cgtgaggttt tttcatttca
     8641 acgatatcgt gcaagtcgta cataaaaata gcctcctttt tgtttattct tcatcaaatt
     8701 gaatattcaa gatatcaaga attcgagtca aatctttttg agaaagatat tcaatctcga
     8761 tcttaccttt cccatttttt tcttggatag ctacacttgt accaaattta tccatcaaac
     8821 gatcttcgct ttctcggata taatatggtt tttcctttgc tagccttggg atttttttct
     8881 tttcttttcc atcattttga tttaactcag aaacaagctg ttccagttgg cggacagtta
     8941 aattttcagt tactgcacga ttggctaatt tcaagatcaa tgttttattt tttaaaccta
     9001 acagcgtacg ggcttgtccc atagataaac gctgatcttg taccatttcc ttgacaagat
     9061 ccggtaaaga aagcaagcgc aaataattgg cgatataagg tctgctcttt cctaaacgac
     9121 tagctacttc tgcttgtgtt agtttcaggt ttttcatcag catctcatat gcttctgctt
     9181 cttctaacgg attcagatct tctcgctgca agttttccag cactgctact tgcatcatcg
     9241 cttcttcgtc aaagtctcta acgatagcag ggatcgtttc tttttcagct agtttggacg
     9301 ctcgaaaacg tcgctcccct gcaataatct catatccttt tactgcggaa cggcgtacga
     9361 tgatgggttg aaagacacct gattgttcaa tagaattagc tagttcctgc aaagatactt
     9421 cttcaaatgt tttacggggc tgatacggat ttggtcgcag ctcattcaat ggtagctgga
     9481 caacggtatc atcttttaca tccaccgtct ctaagttttc taaatcttga aacagtgcat
     9541 cgattcctcg gcctaatcct ttacttttct tcacgactta ccacttcctt tgccaatgct
     9601 tggtagactt cagctcctcg agaacgtgga tcgtagtcga tgatcggttt tccatgacta
     9661 ggtgcttctg ataaacgaat atttcttgga atgatcgttt cgtaaacttt ttcgcggaag
     9721 tatttacgta cttcttctac gacttcattt cccagatttg ttcgtgcatc atacattgtc
     9781 agtaagactc cctcgatctc taattctgga ttaaagtgtt tttggactaa acgaaccgta
     9841 ttcagtaatt ggcttaatcc ttccaatgcg taatactcac actgaacagg tatcaaaatc
     9901 gaatcacttg ctgtaaatga attgattgtc agatggccaa gagaaggcgg gcaatcgatc
     9961 aaaatataat catactgact gcttacttct gctaaagatc cttttaatct tgattctctt
    10021 gccatcattg acgtcaattc gatctctgct cctgctaatt ggagagtcgc aggcacaata
    10081 ctcaaatttt cgtgttcagt gatcaaagtt gcctcatcaa ttggcaattc attgactaga
    10141 acatcataga tgtctcttgt cacatcaggt tttctgatcc cgacaccact ggtagcattt
    10201 ccttgtgcat ccatatccac tagcaatact tttttgccaa ggctagcaag acaagcacct
    10261 agattcaccg tcgtcgttgt tttgccgacg ccaccttttt ggttcgcaac agatattatt
    10321 tgtgccatct cttctcctcc tatttgattg gctgcttatt aggcagtccg ggctttcttg
    10381 ggtatttctt tggggttggt ttcttttttt gaataacgat gatatgccgt tgatcagaga
    10441 cattcggcaa ggtaaccgcc tcttctttga ggaatttacc acctaataaa gcaatcgctt
    10501 gttttgcttc tgtcaattcc tcttcacttt ttgctgcttt caatgcataa aaatagcctt
    10561 cttgtttagc caagggcaaa cacaattccg ctaacacatt caaacgagca accgcacgag
    10621 cagtgacaag gtcaaatgat gcacgaaagt gaggattttg cccaaatgtt tctgcccggt
    10681 catgatataa ggaagcatcg attcctaata atcgggttaa ctcagataag aaggttattc
    10741 gtttattcag agaatcaacg atcgttatct gcagttctgg aaaggcaatt tttaaaggta
    10801 tgctaggaaa ccctgccccc gaaccaacat cgcataaaga taaaggttgc gtaaagtcta
    10861 cttcaaatgc taatgtaagt gaatcgtaaa aatgcttcag atatacgtct ttttcatccg
    10921 taatagctgt aaggttcatc ttttcgttcc attcgactaa tgtccgataa taaatagcga
    10981 attgattcat ttgatgatcg gtaagctcta tccctttttc tgccaaggat tggcgaaatt
    11041 cttctggtat cataaatatt cctttcattg tgaaacagca attgtttcac agattctctc
    11101 cctactttaa cgcaaaatct ctagacatgc aatccttcca tatggattct taaaaatttg
    11161 aaaagtaaga aaagccgata gactttttct ttctagtatg actcataaaa tatacacaga
    11221 agagagaact agctttgagc aatttctgca aaaactagtt ctctcttcta tttattatta
    11281 cgtattacgc tggttcactg actttcgcaa tcttcccttg ttcgatatag accattagga
    11341 tacttaggtc tgcagggttt acgccactga ttcggctagc ttgggcaatt gtttctggtt
    11401 ggattttctg caatttttgt tttgcttctg ttgctaatcc gttgattgct gcgtagtcga
    11461 tgttttctgg aatctttttc gcttccatgc gttttaattt ttctactttt tccatggctt
    11521 ttttgatgta gccttcatat ttgatttgga tttctacttg ttcgatttct tttcgtgtca
    11581 attcttcatt ttctggaata aaccgtagaa gttctgcata agtaatctca ggacgtctta
    11641 aaaagtcgct tgctagtaca ccatctttta atggtgccgc attaatcgtt gctaaaaagt
    11701 cttggacttc ttctgttggt ttgattcgta cattcatcaa acgtttgatt tcttgttcaa
    11761 ctgcttcttt tttcttcaaa taattcttgt attgatcttc ttttactaag cctacacggt
    11821 gacccatttc tgttaatcgc aaatctgcat tatcatgacg taaaagcaga cggtattcag
    11881 cacgtgaagt cagcaaacga taaggttcgt tcgttccttt tgttaccaaa tcatcgatca
    11941 tgacaccgat gtaaccgtca cttcgtttga tcactaaagg ttcttttccc tgaactttca
    12001 aagctgcatt gataccggca atcagccctt gtccagccgc ttcttcataa ccgcttgtac
    12061 catttgtttg tccagctgta taaagatttt caacgacttt agtttctaat gtcggacgga
    12121 gctggtgtgg ctctactacg tcatattcga tagcatatcc tgtacgcatc atttctactt
    12181 tttctaatcc agcaatagaa tgaagcatgt tgacttgaac atcctctggt aaagaagtag
    12241 ataaaccttg aacatagact tcttccgtat ttaagccttc tggttccaaa aataattgat
    12301 gacgtggttt gtctgcaaaa cgcacgatct tatcttcgat ggatggacaa tagcgagcgc
    12361 ctaccccttc aacgatccct gtaaacattg gggcacgatg taagttgtct cgaataattt
    12421 ggtgagtcgt ctcacctgta taggtcagcc agcaagattc ctgatctagt ttataggcac
    12481 tatctggtgt gctgaagcta aaatgattcg gctctttgtc accaggctgc tcttctgtaa
    12541 cagaatagtc gatcgtactt gattttactc gaggcggtgt tcctgttttg aaccgttcga
    12601 tagcaaagcc aagttctttt agatgattcg ctagtccaat agaaggttga gagttattcg
    12661 gacctgatga atatttcaat tcaccgataa tgatttctcc gcgaagtgct gttccggctg
    12721 taataacaac tgctttggcc cggtagctcg ctcctgtgga cgtcactact ccatgacaaa
    12781 caccatcttc gacgatcagt tcttcgacga ttccttgtct tagcgtcaaa tttggttctt
    12841 tttcgatcgt atgtttcatt tctgttgaat aagcatgttt gtctgcttgt gctcgcaatg
    12901 ctcggacagc tgggcctttt cctgtgttca acatacgcat ttggatatag gttttatcga
    12961 tattcttacc catttctccg cctaacgcat cgatttctcg aacgacaacg cctttagctg
    13021 gtccgcctac agaaggatta catggcatga atgctaccat gtccaaattt attgtcagta
    13081 ataatgtttt tgatcccata cgtgcagcag caagtgcagc ttctgaaccg gcgtgtcctg
    13141 cgccaacaac gatcacgtca tacgcatctg cttcataatg ttccaatcgt ttgttcctcc
    13201 ttttattttc ctaaacaaaa ttgactgaat aattgagtga ttagctcatc ttgtacactg
    13261 tcgccgacaa cttctcctag atagtcccag caacgcgtca tatctatttg aacgagatcc
    13321 acaggcattc ctgaatcaat acctgcaatg acttcttcaa gtgagaggga agctttttct
    13381 aacaacgcga tatggcgggt attagaaaca taagtagcgt ctctttctcc tgtttctccg
    13441 ctgaagaata aatcagaaat agctgattcc aaacgatcta gtccgtcgtt tttagctacg
    13501 gaaattgaaa aaactggttc attttcgatc aatttcttca atttttcttg ttccagctgt
    13561 gctggcaaat ctgttttatt tagaagaatg atccgtttca atccacttgt cgcttccaat
    13621 aattgttcat cttctgctgt cagtggttcg ctttggttta gaacaagtaa gatcaagtct
    13681 gcttctgcta atgcttttcg gcttctttcg accccgatcc gttccaccac atcttctgtt
    13741 tcccgaattc cagctgtatc gattagcttg agcggtaccc cccgaacatt gacatactct
    13801 tcgattacat ctcgagtcgt tcctgcaata tccgtaacga ttgctttttc ttctcttaac
    13861 aaatggttta acaaacttga tttgccgaca tttggccggc cgatgattgc cgtacttaac
    13921 ccttcccgca gaaccttccc ttgcttggat gtagcaagta gcgcttggat tctttgttgg
    13981 atcatctgcg ctttttcaag caataacttc gtagtcaatt cttcgacatc atcatattct
    14041 ggataatcaa tatttacttc tacttgtgct aatgtctcta aaatctcttg tctcaatgag
    14101 cggatcaaag cagacagatt gccgtctaac tgattaagag ctagtcccat tgctttgtct
    14161 gtttttgccc gaatcaaatc catcacagct tctgcctgtg aaaggtcaac acgaccattc
    14221 aagaatgctc gttttgtgaa ttcgcctggc tcagctaatc ttgcaccttc tcttaacaat
    14281 agctgcaaaa tttgattgac tacaacgatc ccaccgtgac aattgatttc tactacatct
    14341 tcccgcgtaa atgtctttgg tgctctcatc acggagacca tgacttcatc gacaagctga
    14401 ttgctcttgg gatcaacgat atgtccataa tggatcgtat gacttggtac ttctgataat
    14461 cgtttgtttc cagattgata aactttatct gctagttgca cagcttgatc gccacttaaa
    14521 cgaacgatac tgattgcacc ttctccaggt ggggtagaaa ttgccgcaat cgtatcaaat
    14581 tctaaagtaa tttcagccat tttttcactt cctttttcat tttgcgcaca aaaaaagtgc
    14641 ccactccacc ctttatgcac aataaacggt gaacttcgca ctttgactgc ttgttcttga
    14701 ttaaattctg gtcatagatt atcacacttg ctataaggaa tcaagtgttt aaaacaatta
    14761 gatgaagttg agcctgttct gcttccatta ccttatattt aattgtcctt ggatgtctct
    14821 ttgcgttctt tggtttattc gaagagaaga tactgtataa acaaggcttt atctttctta
    14881 aaaaaaacgg tacactaaat ggtagcgcta tctaaactat acacttttga aaggagaaaa
    14941 tatgtgagcc cgttcagatc tgctgcattg gaagaagaaa gtgaccctcg gatcaacgat
    15001 gtcgttttat ctacagggaa tatcaaccag aaatatatcg tccgcgatat cgtttttgtt
    15061 gtggaatgct tagaagctga tttgtttgac ccatcttttc ccaaagatga ccttttctta
    15121 acaacgaaga ggaaattaaa gacgaaggta cttgaatatg gtgcgaatgc agtaatcaac
    15181 tgtcattttg agtatcagca aaaaaaacgc gacggaaagt attttctgga actttttgct
    15241 tatggaacag tgatccaatt tatccaaaca acgattggtt aaatgaaaca gacaaaaaaa
    15301 gcggatcaaa actgaagaca gtttcgatcc gcttttttct atcaaagtta gtgactactt
    15361 catcgtatac tctgataaga atgatttcta gtaaaatata cttggtttga aaaactttgt
    15421 caacgtgatt tattcaaaaa gtaatggaat caataatatt ttttagcagg ttctactact
    15481 aaataacgat aaggttcctc accttccgaa tgtgttttta catgttcatc tttgcttaat
    15541 gcagcatgga tttgtttacg ttcaaatgca ggcattggtt ctaagaaaac aggctgccct
    15601 gtccgtttta ctttttcagc cgtgcgatca gctaaacgct gaatgatctc ttggcgcttt
    15661 tcacggtaat tgcctacatt gactactaca gacagcttat ttcttgctaa acgatggatg
    15721 aagacttgtg ccagatattg caatgcattc agtgtttttc catgtttccc aatcagtatg
    15781 ccttgctttt gtgtttctaa atggaaaaca accatattat ttgattctct ttccattttg
    15841 acaagagctg gagcatcaag ctgttttgaa atttcagtaa gataaactgc caattccgtt
    15901 aaagctgctt catcacctag ctcacttact tcttctgttt tttcttcaag aatcgtttcg
    15961 ttgactacct cgatctcagc tgttggttct tcttccaaaa tttcttctac agtctgttct
    16021 actgtttcag aaactttttc gctgatactt ggctggatcg aaagccgtgc attctttcga
    16081 cccattccta ggaaaccttt ttttccttct tccagtattt cgatttcgac ttggtctttg
    16141 gccaaaccca aatcagccag acctagttgg acagcttcgt ctattgttgc agcttcataa
    16201 atcggcatta gcattacctc ccctattatt tccgtttttt cttaggattc attgctttct
    16261 taagagcacg ttctctttcg cggattctcc gtgcttcttc ttcacgctct tttcgaattt
    16321 tgaaagggtt gttgatcagc agcgtttgta caacttggaa ggcattggaa actacccagt
    16381 ataatgaaag accgctggct aaattgacac ccatcactaa aatcattaca ggcatcacga
    16441 aattcatgat cttcattgat gcattcgatt caatttgact catgctagat aaatacgtac
    16501 ttgcaaaagt aaagattgct gctaaaatcg gcaaaataaa tgttggatcc gcgttcccta
    16561 agttcaacca taagaaatgc ccttgtttca actctggtac acgtgaaata gattgccata
    16621 acgccatcaa gattggcatt tgtactaata aaggaagaca accagcatat ggattgacgc
    16681 cattttctgc atataaacgc tgctgctctt ctcttaactt actttgtgtt tccggatctc
    16741 ttgaactata ttgttgctgc agtgctttta atttcggttg taattcttgc gttttacgca
    16801 tgctctttgt ttggaaatgc atcaacggca ataggatcac gcggatgatc agtgtaaata
    16861 aaatgatccc tatccctgca ttaccaaatg acaacgcctt gatcgcctca gcaaagtaat
    16921 aaacaatata acgatcccaa attcctgtac tctgtgcgct gacttcccca gttccgcaac
    16981 cggataagac gatgaccaaa ctaacgatac cggccatcaa aagtaaacgt ttgtatttct
    17041 tcacttactc ttttcctctc tgtcgattat ttttgcaagt tttaagacgt ggactaaatt
    17101 ggagcgaacc tcatcataag tcaacccctt cacacttggt ctagcaatca caataaaatc
    17161 caactccgga tcaatttctt cttttataga ataaactgct gctcggattt ttcgtttgac
    17221 ttcattgcgg tttaccgcgt tgccgacctt ttttcctaca gataaaccaa ctcgaaaatg
    17281 aggctgtccc ggtttttcca aacggtaaac gacgaatttg cggttagcaa aagaatctcc
    17341 cgtatggaac acggcttgaa actctcgttc tttttttact cgatacgctt ttctcattag
    17401 ttttctttcc ttttctatct ctcacttacg ctcataatca taccataatt acgattgtcc
    17461 tttcatcatt tccctaaaaa agagtataaa aaaaaccact gaaaccccag tggcctaagc
    17521 tgaaagaact tttcttcctt tgcgacgacg gctagctaac acacgacgtc catttttagt
    17581 actcatacgt ttacggaatc cgtgaacttt ttgacgttta cgtttatttg gttggtatgt
    17641 tcttttcata tattccacct ccaaaatgtt cttatctatt ttataaacac agacatactt
    17701 tgatagtata acgacaaagt agtgattttg tcaatataaa atagaagatc gattgttaaa
    17761 acttatccac aagattattt ttttctatgg gaatcctatg tggaaaaagt tatgcacagg
    17821 gattatccac agataataaa aggctggttt tacacagaaa acacacgtgt aaaaaaagta
    17881 atccacaatc aggcgatttc ctgtgtattc cgtctcctaa ctattggtat atctgtattt
    17941 tttatccaca gacgcaagag gaaatctatt ggtttttacg agttttccac ctgtgcatta
    18001 gtggtgtgga aaactttttt tgacaactgt gtttttctct tttttctttt tgtcgattgt
    18061 gtggataatt gtaattaaaa aatttttttc ttcggtttct gtggaaaact attgaaaaaa
    18121 atgctaaatt agtactagtt attcactttt taatgaagga ggaggcctta tatggtatcc
    18181 ctcgatgctt tatggaatga attaaaagca acataccaaa aggatttatc gcctgctagc
    18241 tataatacat ggatcgaaac agcgaaccct cgaacccttg atcaaaacca gctcgttgtt
    18301 gaggttccta gcaagattca taaagaatat tgggaaaaaa acctggcgac aaaaatcgtt
    18361 gaagtcggtt atatgttatc aggaaatgag attatccctc gctttattac tggcgaagaa
    18421 gcagagcaag aagaagttat agaagaaaaa aatccaaaag ttgtggcacc tagtccgcta
    18481 aaaaaagcca tgctgaaccc taaatatacc tttgatacgt ttgtcattgg taaaggaaac
    18541 cagatggctc atgcagcagc gctcgttgta gcagaagatc caggttctat ttataacccg
    18601 ctcttctttt atggaggcgt gggacttggt aagactcact tgatgcatgc aattggtcat
    18661 caaatgctgc aaagtcagcc taatgccaaa gtaaaatatg taagcagtga aacttttgct
    18721 aatgatttca tcaattcgat ccaaaacaaa acagcagaag agttccgtca agaatatcga
    18781 aatgttgatt tactgctagt ggatgacatt caattttttg cagaaaaaga agctacgcaa
    18841 gaagagtttt tccatacttt caatgccttg tacaatgaag ggaaacaaat cgtactaacc
    18901 agtgatcggt tgccaaacga gattccgaaa ctgcaagaac gccttgtttc tcgctttgca
    18961 tgggggctgt ctgttgatat tacaccgccg gatcttgaaa caagaacagc gattttacgt
    19021 aaaaaagcgg cggctgaacg tctagagatc ccagatgaca cactaagcta catcgcagga
    19081 caaattgatt ctaacattcg tgaattagaa ggtgcgcttg ttcgagtgca agcttttgct
    19141 gcgatgaata gtgaagatat ttcgactagt ctagctgcag acgcactgaa aacgttaaaa
    19201 tcaggaaaag gacatcctca attgtcaatc ctgcagatcc aagaagaagt ggcaaagtat
    19261 tatcacatcc aattgaaaga tctcaaagga aagaaacgcg tcaaatctat tgttgttcct
    19321 agacaaatcg ctatgtattt ggcacgtgag ctcacagata attctttacc gaaaatcgga
    19381 gctgaattcg gtggcaagga tcatacaacg gttatccatg ctcatgaaaa aatccagcag
    19441 ctgatggatt ctagtgtcag tatgcaaaat gaagtatcag aaatcaaaaa ctttttacta
    19501 aattaatttg tcgattctat caactgaaaa tagcatgtgg ataaaagaaa aaaacgttca
    19561 aaagttatac acactttttc cacagctgtt ttttcgtttc tctcttacgt tttttgagtt
    19621 ttccacagaa tcaacatgcc ctattacttt tattattctt tttaactaat aataaataaa
    19681 caaacattca aaggagatac atcatgaaag ttactttaaa ccgagctagc tttatgcagg
    19741 aattgcaaac tgttcaacga gctatttcaa gcaaaaccac gatccctatt ttgacaggtg
    19801 taaaaatcac actgacacaa gaaggtttga ctttgacggg gagcaacgct gatatatcaa
    19861 ttgaaacttt tttgtctgtt gaaaacgaaa aagcaaatat gcaaatcgaa tctactggtt
    19921 ccattgtttt acaagcacgt ttctttagcg aaatcattcg gagacttcct gaagaaacat
    19981 ttactttaga agttttagaa aataaacaag tagcgatcac ttctggaaaa gcgaatttta
    20041 tcgtaaatgg attagatgca gataactatc ctcatcttcc tgttgtcgaa agccataacc
    20101 agatgaaatt acctgtacac gtattgacta aactaatcaa cgaaacagtt tttgctgtct
    20161 cacaacatga gagtcgtcca atcttgacag gtgtgcattt cattttatct gataattctt
    20221 tattagctgt agctactgat tctcaccgtc taagtcaacg cgtgattcca gtagaacaag
    20281 cggctgatca ttttgatatt gttattcctg gaaaaagttt gatcgaatta tctcgctcat
    20341 taacaaatga agaagaaatc gtcgaaatca gcattatgga aaaccaagtg ttgttcaaaa
    20401 cagaaacgat gtatttctat tcccgtttgc tagaaggaaa ctatccagat accaatcgtt
    20461 tgattccttc aagttttaat acagaggttg aattttctgt tcctagcttt ttagcggcga
    20521 tcgaacgggc ttctttactt tctcatgaag gccgtaacaa catcgttcgt ttatctattc
    20581 gtccagatgc ggttgtttta tacggaaatt cgccagaaat cgggaaagta gaagaaagct
    20641 tgagttatac agcaagcagt ggcgatccat tagatatttc tttcaatccg gattatatga
    20701 aagcagcgtt gcgtgcattt ggagatatga gcatcaaagt gaaatttatc tctgctattc
    20761 gtccatttac attggaacca acggaagatg gcgttcaatt tattcagctg attactcctg
    20821 tacgtacaaa ttaacaatga ttttcaatgt tcttgaaaat ttaattgaaa agaaatagaa
    20881 aaaataaaat tttaaacaga aggccctaaa atctctttta aggctttctg tttatttttg
    20941 tttaaatcac cttttttaga ttaaatcgtc ttatatggaa aaatatatgg ataaatttgt
    21001 tttattgcga aaaaaaaggt ataatagagt atacttttaa taatgaaaat gagggatggg
    21061 cattgaaaca acaagtcatt ctaaatacgg aattcatgac gttgggccaa atgttgaaag
    21121 aagtcacagt tatcggtagt ggcggacaag caaaatggta tttggcagaa aacactgtgt
    21181 tagtcgatgg cgaaccagaa aatcgtcgtg gacgcaaact ttatcccggc atgatggttg
    21241 aagttccaga agtaggaact ttttttatgg taaaaaaagg aaacgacgat aatgaggctg
    21301 aataagctgt atttaaaaaa ttatcgaaat tacgaagagc tgaacatcga attttccaag
    21361 aacctcgtca tctttttagg agaaaatgcg caaggaaaaa cgaatctttt ggaaagtatc
    21421 tacgtattag ctatgacgcg aagtcatcgg acaagtagtg agcaggaatt gattggctgg
    21481 actgacgatc aggcgatgat tcaaggagag atcacaaaag gttcatccac tcttccatta
    21541 gaaatcttat tatctaaaaa aggccgaaaa accaagatca accatatcga acagaaaaag
    21601 ttaagtactt acgtgggaca aatgaatgtc attttatttg caccagaaga tctttcttta
    21661 gtaaaaggca gcccgcagat caggcggaag tttttagata tggaattagg ccagatcaat
    21721 ccaatctatc tttatgatct tgtccaatac caagcaattt tgaaacaaag aaaccagtac
    21781 ttgaagcaat tgaatgaaaa aaaacaaact gatttgcttt atttggatat tttgtccgaa
    21841 caactagcag cgtttggcag caaagtattg aaagcaagag cacagttcgt caagcgattg
    21901 gagttttggg ctaattcttt gcatcagcaa atcacccatc aaaaagagca gctggaaatc
    21961 gagtatctca ccgcagtcga ttctttagaa acacatacgc aagagcaaat ccaagaacaa
    22021 tttctcgcac ttttgaacca aaataaaaag aaagaccttt ttcggggaac aacgacagtt
    22081 ggtcctcatc gtgacgatct ttcctttttt attaatcaga aaaatgtgca gacttatgga
    22141 tcgcaaggac agcaaagaac aactgcacta agtgtcaaat tagcagaaat cgatttgatt
    22201 aaagaagaga caggggaata tccaatcctt ttgttagatg atgtgatgag cgagctggat
    22261 gataatcgtc aactccatct gctagaaaca atcgaaggaa aagttcaaac gttcttaaca
    22321 acaacgacac ttgaccatgt aaaaaataaa atgactgttg aacctgagat tttttatgtt
    22381 caacaaggga aactaaaagg agaagaaact gaatgacaga agaaagaagt ttagtagaac
    22441 gcgctaaaga gtatgatgcc agtcagattc aagtacttga aggacttgaa gccgttcgta
    22501 aacgacctgg catgtatatc ggttcgacta gttctgaggg tctgcatcac cttgtttggg
    22561 aaattgtcga taattcgatc gatgaagtat tagcaggttt tgcaacgaaa atccatgtga
    22621 ttattgaaaa agacaacagt atcaccgtta ttgacgacgg tcgggggata cctgtagata
    22681 tccaggcaaa aactggacgt cctgcagttg aaacggtctt tactgtttta catgctggag
    22741 gaaaattcgg cggtggtggg tacaaagttt ctggtggact tcacggagta ggatcttctg
    22801 ttgtaaacgc gctttctaca cagcttgatg tcaaagtata caaagaagga aatgtgtact
    22861 atcaagaata tcgtcgtgga gctgtagtgg acgacttaaa gattatcgaa caaacggatc
    22921 gccatggaac aacggttcac tttacgccag accctgaaat ttttacagag acaactgagt
    22981 ttgatttttc aaaattggct acccggatcc gtgaacttgc tttcttgaac cgcgggatgc
    23041 gtatatcgat tgaagacaaa cgagaagaag aaccagtcat caatgaatac cattatgacg
    23101 gcgggatcaa aagttatgtc gaatacttga atgcaaacaa aaccgtgatt tttccagaac
    23161 ctgtatattt ggaaggtgaa cagcaagata tcgcagttga agtctctatg caatatacag
    23221 acggctacca ttccaatatc atgagttttg ccaacaatat ccatacgtat gaaggtggaa
    23281 cacatgaatc aggattcaag actgctttaa ctcgtgtgat aaatgattat gcccgaaaac
    23341 aaaagctgat gaaagaaaat gacgacaact tgaccggtga agacgtgcga gaaggattga
    23401 cagctgttat ttctatcaag catcctgacc ctcaattcga aggacaaaca aaaacaaaat
    23461 tgggcaattc cgaagtacgg acagtcactg atcggttatt tagcgaacat ttcatgaaat
    23521 tcttgctgga aaacccaagt gtgggccggc aaattgttga aaaaggatta ctagcttcca
    23581 gagctcgtct agcagcgaaa cgtgcgcgtg aagtaacgag acgtaaaggt gctttagaga
    23641 ttagtaatct gccaggaaaa ttagcggact gctctagcaa cgatcctgaa aaatgcgaat
    23701 tgttcatcgt cgaaggagat tcggccggcg gatcagctaa gcaaggtcgt aatcgagagt
    23761 ttcaagccat cttgcctatt cgtgggaaaa tcttgaatgt tgaaaaagca agcatggaca
    23821 agatcttggc aaatgaagag atccggtctt tatttactgc tatgggtaca gggtttggag
    23881 aagattttga tgtatcgaaa gctcgctacc acaaattagt tatcatgact gatgccgatg
    23941 tcgacggcgc gcatatccgt acattgctgc tgactctttt ttatcgttac atgcgtccta
    24001 ttgttgaagc tggatacgtc tatattgctc agccaccttt atacggggta aaacaaggga
    24061 agaatattac gtatgtacaa ccaggaaaaa atgcagaaga agagttgaaa caagtcgttg
    24121 cttcacttcc tgcctcacca aaaccaagcg ttcagcgtta taaaggactt ggagaaatgg
    24181 atgatcatca actatgggaa acaactatgg acccaagcaa tcggatgatg gcccgcgtca
    24241 gtgtggacga tgctattgca gcagatcaga tatttgaaat gttgatgggg gatcgagtag
    24301 aaccccgtcg tgcattcatc gaggaaaatg cacactatgt gaagaactta gatatttaat
    24361 catgaaggag gaaaaagaat gagtgaagaa atcagagaaa acatccatga tgtcaatcta
    24421 accagcgaaa tgaaagactc cttcatcgat tatgcgatga gtgttattgt cgcacgtgca
    24481 cttcctgatg tcagagatgg tctgaaaccc gttcatcgcc gtattttata cggcatgaac
    24541 gaattaggtg taacaccgga taaagcccat aaaaaatctg ccagaatcgt cggagatgtc
    24601 atgggtaaat accatcctca tggagacatt gcgatctatg agtcaatggt acggatggca
    24661 cagccattca gctaccgtta tatgctagtg gatggtcatg gaaactttgg ttctgttgac
    24721 ggtgacggtg ccgccgctat gcgttatacc gaagcacgga tgagcaaaat cgctacagaa
    24781 atgctgcgtg atatcaataa gaacactgtt gatttccaaa gcaactatga tgatacagaa
    24841 aaagaaccag ttgtactacc tgctcgcttc ccgaatcttt tagtgaacgg aacaacgggg
    24901 atcgccgtag gtatggccac gaatatccca cctcataact tgtctgaggt agtagcggct
    24961 atcgatttgc tgatggataa tcctgatgtg acgaccaatg aattgatgga agtattacct
    25021 ggaccagatt ttccaacagg tggtttggtt atggggaaat caggaatccg aagagcgtat
    25081 gaaacaggta agggttctat taccgtacgt gcaaaagttg agattactga gatgccaaat
    25141 ggtaaagaac ggatcatcgt gacagaattg ccttatatgg tcaataaagc aaaattgatc
    25201 gaacggattt ctgaactgca cagagacaag cgtatcgaag ggatcacaga tttgcgggac
    25261 gaatcttccc gtgaaggtat gcggatcgtc attgacatcc gtcgtgacgc cagcgcatcc
    25321 gttatcttga ataacttata taaattgaca tccttgcaaa attcatttgg attcaatatg
    25381 ttggcgatcg aaaaaggtgt gccgaaagtt ttgagcttga aacaaatcct tgaaaactat
    25441 atcgaacatc aacgcgaagt catcacacga cggacggtct ttgaaaaaga aaaagcagaa
    25501 gcaagagcac acatcttaga aggtttgcgt attgctttgg atcatatcga tgaaatcatt
    25561 gcgattatcc gcgggtctaa atcagatgac gaggcaaaag caacaatgat cgaacggttc
    25621 gatttatccg atcgccagtc tcaagctatt ttagatatgc gtttacgccg attgaccggt
    25681 ttggaacggg aaaaaatcga aaatgaatac caagaactct taaaactgat tgaagattta
    25741 actgacattc tggcaagacc agaacgtgtt acagaaatca tcaagaatga attagcagac
    25801 ttgaatcaac gatttggtga taaacgacgc acagaattac tagtcggtga ggtcttaagt
    25861 ctggaagatg aagatttaat cgaagaagaa gaaatcgtta ttacattgac aaacaatggt
    25921 tacatcaaac gtttggcaaa taatgaattc agagctcaac gaaggggtgg acgtggtgtc
    25981 caaggaatgg gtatccacaa tgacgacttc gtcaaaaatc tggtttcttg ttctacccat
    26041 gatacattgt tattctttac gaataacgga aaagtgtatc gggcaaaagg atacgaaatt
    26101 ccagaatacg ggcgtacagc caaaggaatc ccaatcatca atttactagg tatcgattcg
    26161 agtgaaagca tccaggcaat cattgcggtg acgggagaag cagaagaagg ccactatctc
    26221 ttctttacga cgcgtcaagg tacagtaaaa cgtacttctg tcactgcttt tgctaacatc
    26281 cgaagtaatg gtctgatcgc aattggtttg aaagaagacg atgagctcgt caatgtgcta
    26341 ctgacagatg gtcaatctaa tatcattatt ggaacacata acggctactc tgtcactttc
    26401 aaagaagaag cagtccgcga tatgggacgt acagcttccg gggtcagagg gatacgcctg
    26461 cgtgaggaag attatgtcgt tggggcagcc ttaatgaagg aaaatcaaga agtattagtg
    26521 atcacagaaa aaggttacgg aaaacggaca aaagtatcgg aatatccagt gaaaggccgc
    26581 ggaggtaaag ggatcaaaac ggcgaacatc actgaaaaaa atggtccact agctggattg
    26641 accactgttt ctggagatga agacatcatg ctgattacag ataaaggtgt cattatccgt
    26701 ttcaacgtat cgactgtttc tcaaactgga cgttcaacat taggcgtacg tttgatgaag
    26761 atggaagctg atacgaaagt tgtcacgatg gcagcagtcg aaccagaagc tgcagaacaa
    26821 acagttgaag aacaaggatc agaagaataa ccatcaagac taagtgtgta agctagcaag
    26881 aataaccgat taaaaaatct ggttattcct gctggctttt ttgattagtt gaatttctct
    26941 taaaatattc gaaactgttc attctgtatt gcttttgacc aaaatagagt gtataattag
    27001 agcttgtgag tagtctaatt aattagataa ctctccttgc tcttaggaac ctaagagccg
    27061 aaagtccaca gggaggtgaa tatcaatgga aaacacgaaa tatgaaatca tgtacattat
    27121 tcgtccaaac attgatgaag aagcaaaaac tgctttaatc gaacgtttcg atgcaatctt
    27181 gaaagataac ggagcagaag ttatcgaatc aaaagattgg gaaaaacgcc gtttcgctta
    27241 tgaaatgaac ggttaccgtg aaggtatcta tcacatcgtt aaagtatctt ctccatcatc
    27301 agcaaatgct gtcaatgaat ttgaccgtct tgctaaaatc aacgacgata tcattcgtca
    27361 catgattgtt aaagaagaag cttaattgtt gtttcatgtg aaacaataga aaacgatgag
    27421 aggagatgac tattttgatt aataatgttg tattagttgg acgtctgacg aaagatccag
    27481 atttgcgtta cacagcaagt ggtacggcag tcgcaacatt tactttggct gtgaatcgta
    27541 attttacaaa ccaaagcggc aatcgcgagg ctgattttat caactgtgtg atttggcgca
    27601 aatcagcaga aactttagca aactatgctc gtaaaggaac acttttaggt gttactggac
    27661 gtatccaaac tcgttcttat gataatcagc aaggacaacg tgtatacgtg acagaagtag
    27721 tagctgacaa cttccaattg ctggaaagtc gttctgcatc tgaaaatcgc caacaaagcg
    27781 gcggattcca aagttctggt caatcagctg gcggatttgg cggaaacaat aactctaatc
    27841 aaacatctca atcatccaac ggtatgcctg atttcgaccg tgatacttct gacccattcg
    27901 gctcaagttc aacgatcgac atttcagacg atgatttacc attctaaacg aatttgatag
    27961 gagggaaata gaatggcaca acaaagaaga ggcggacgta aacgtcgtaa agtagactac
    28021 attgctgcta accatattga atatatcgat tataaagata tcgaattact aaaaagattt
    28081 atttcagaac gcggtaaaat cttgccacgt cgtgtaactg gtacaggcgc taaaaaccaa
    28141 cgtaaaatta ctgttgcaat caaacgcgct cgtatcatgg gcttgctacc tttcgttagc
    28201 gaagactaat aaatcctagg aattgaatga ctgatccttt tgatcagcta ttcaattcct
    28261 ttttttctgt aaaaataacc tctattcgtt tagtcgctcg aatgacgaaa gttatggtaa
    28321 aatcaaatta gtcatatatg ggaggaaaat tatggaaaat aaaaacaatc atttatcccc
    28381 gaaacctctc ttccttatcc tgtttatatt aatcgaagta ttggtagtct taattttacc
    28441 atttcgtttt gttagcgctt cggtcattct attgatgaat ttatggggtg ttcgctattg
    28501 gttgaaaatg aaacgttggc ttattttaaa taaacgtgaa aaaatccagc aggcttcgac
    28561 tgtagctgaa accaatctag cttatgtctc agaagtcatg cctgtaggag tgattgctta
    28621 tcagccatca agccaaaaaa tcgaatggct caatccatta gcattgaaaa tcaaagatca
    28681 aagtggatta acagaggaag aattgctaga tacttttttt actgcaaaag aaaaaaagaa
    28741 aaaccaagtc tatctagcag ataaaacatt tcagtttgat atggatacag taaagggtgt
    28801 tgtttatttt aatgatatta cccaaaacca gttgttaaaa ctccatcaga cgaacagtca
    28861 gccggtgatt ggtattttat ctattgataa ctatgcagat gccattgata aattagatga
    28921 caaagagatt tcttatttga actctttcgt cactacacta gtttctgact ggatgaatga
    28981 ataccatgtc tttttcaaaa gaatcaacgc agaacggttt ttcttcgtag cacagatgat
    29041 cgatctgaaa aagatgatgg ataaaaaatt tgatttgctg gatcgctttc gagcagaagc
    29101 tgaaaaacag agctcgccta tcacccttag tatggggatt gcttatggct caagaaccct
    29161 cgatgaaatc ggtggagaag ctcagaataa tttagatgtt gctttagtcc gtggaggcga
    29221 ccaagttgtc gtgaaagagg taaaagaagg agcaaaacct gtttattatg gggggaaatc
    29281 tgctaagaat gtcaaacgca cgcgtgttcg ttctcgagcg atgagtaccg ctttgcgtcg
    29341 gatttttgat gaaacaggcg atgtgtttat catggggcac aagtttccgg atatggatgc
    29401 tttaggctct gcttttggtg tcagttgtct ggcacgcttc aaccagaaaa aagcttacat
    29461 cgttatcaat gagaacgaga tcattccaga tgtagaacgg tgtcttgaag aaatccataa
    29521 gcatcctgaa ttagaaatgc aactaatctc tccagaacgt gccatagagc tgaaaaaaga
    29581 agaggacctc ctcgtgatgg tggattacca taaaccttct ctatcgatct ctcagggcct
    29641 atatgagcaa tttgataaga ttgtgatcat tgatcaccat cgtcgtgggg aagagtttcc
    29701 aagtaaacct ctgctgactt atattgaatc ttcagcttct tcagcttcag agctagtttc
    29761 tgagctgatc caataccaaa gcagcaaaac aaatcgctta gatcgttttg aggccacatt
    29821 attgcttgca gggatggttg tagatacaaa tagtttcaat gtccgtacaa ctgcacgaac
    29881 ttttgacgtt gccagctatt taaggtcttg tggagcagac gcatccttag tacaatattt
    29941 attgagctcg gatttagcga catacttgga gatcagcaat ttgattgctg gaagcgacta
    30001 tgtgacttct gatattgttg tggcggcagg gacagacgaa aaagagtata atagtgttat
    30061 agcagcaaaa acagcagata cattgctttc gatgatcaat atcaatgcag ctttcgtcat
    30121 tacaaagcgg acagacggct tgattgggat cagtgccaga agtaccggca cgatcaacgt
    30181 ccaaatcatc atggaatcct taggtggcgg aggacacttc acaaacgcag ctactcaact
    30241 ggaaaatacg acagttgagg aaacaaaaca gaagctattt gctgcaatca aagaaaatat
    30301 gaatcaaata tatgataagg agtaatccaa atgaaagtaa tttttttaca agatgtaaaa
    30361 ggaaaaggta aaaaagggga catcaaagaa gttccagcag gttatgcaca aaattatcta
    30421 atcaaaaata acttggcaaa agaagcaacg aaaagcagta tcagtcagtt agcaggacaa
    30481 aagaaagcac aagaaaaaca cgaagctgaa atcttggaag aagctaaaaa gttaaaagaa
    30541 ttcttggaaa aagaagatac tgtagtcgaa ttgaaggcga aagcagggga agacagccgt
    30601 ttgtttggtt cgatcccttc aaaacaaatt gctgaagggt taaacaaaca atacaaaatc
    30661 aaattagata aacgaaaaat cgaattagaa aatccgatcc gttcactagg ctacacaaac
    30721 gtacctgtta agcttcatca tgaggtgacg gctacgatca aagttcatgt cgtacaagaa
    30781 taacaaatct tgatagcgat gttcagctgg taagtataac cagaaggaaa aaagacaaac
    30841 cgaaatttat ctgagaaaac agctgcagca atgaaagcaa aagctgcaaa tcgatttcag
    30901 attgatttcg gtttcttttt tgggaacagc aaaatagcat aaagaaaacg agtataataa
    30961 aagagaacta tttttttatt acactttcgg tacgaatgat gacttttctc tcattttctt
    31021 gtaaaatgaa gcaattgaag acaaggagcg atacgtatga atgaagtgtg gcaggatcga
    31081 atcccaccgc aaaatattga agctgaacaa gcggttttag gctctgtttt tcttgacgca
    31141 gaaacgatca ttgatgccat ggagtacata gagccaaaag acttttatcg tcgtggccat
    31201 caaattattt ttgagacaat gatcgagtta aatgatcgta atgaagcgat tgacgtggtt
    31261 actgtcaaag accggctgga acaagccaat ttgttagaag atgccggtgg tttaagttat
    31321 ctctcagact tggcattagc agttccgaca gcagcaaata tcgtctacta tgcgaaaatc
    31381 gttgaagaaa aatcattgct gcgtacattg atccagacag caacaggaat cgttacgaaa
    31441 ggattcgagc aaggagaaga agttcaaaca attttagatg atgccgaacg cagtatcttg
    31501 gaggtttcgg aaaaaagaaa tcgaagcggc tttttatcta ttgctgaagt actgaactcc
    31561 acgattgaaa atatcgatcg actagctcaa aacaatgaag aaatcacagg tctaccaact
    31621 ggctatcaag gtctggataa aatgacagca ggtttccagc ccgaagaact aatcattctt
    31681 gctgcacgtc cagcggtagg taaaacagcg tttgcattga atattgctca aaatgtagga
    31741 acaaaaacag atcgttctgt tgcgatattt agtttggaaa tgggggcaga atctcttgta
    31801 aatcggatgc tttgtgcaga aggttcgatt gaggccagcc atttacgtac aggtcagctt
    31861 tcggaagaag aatggtcgaa tctgatcgtt gcgatgggga gtctttctcg agcaaatatt
    31921 tttatcgatg atacaccagg gatcaaaatc tctgaaatcc gtgcgaaatg tcggaaacta
    31981 gcgcaagaaa aaggcaatct aggcttgata ttgatcgatt atttgcagtt gattgaaggt
    32041 aacggtaaag agaaccgtca acaagaagta tcagatatct ctcgccaact gaaaaaactg
    32101 gcgaaagagc tgaaagtacc tgtcattgct ctttcacagt tatctcgtgg agtagaacag
    32161 cgacaagaca aacgaccagt gctaagtgat attcgtgaat ccggatcaat tgaacaagat
    32221 gcggacatcg tagccttctt gtatcgagat gattattatg aaagagaagg cggagatgac
    32281 gatgatggaa acgagccaaa aaatgacaac gtcatcgaag tcatcatcga gaagaaccga
    32341 agcggtgcac gaggaacagt tgaactactg tttatcaaag aatacaataa gttttcgtcg
    32401 ctttcgccaa gagaagaatt ttaaagaaga ggttgtgagc cttgagcaat cccgagagct
    32461 ctcgtaagaa gatgcaagga gtaaccgcag gaacgactag agtacttaat ttaaacagat
    32521 ctccaaaggg attgtgacaa aagtcttgtc acagtccctt tttccgaata aacggtgttc
    32581 aatcagctga cccttggtat tagctcagca aacgtcaaaa tatgaggaac tattttgacg
    32641 tttgtttctc taatactcag gtcaaaacgc tgatcttacg acctcttttc cttaaacggt
    32701 gttctcctgc caactcctcg gtcacaagtc acaatatcat caaacatgag aagcagtttt
    32761 ttgaaattgc tccttgtgac tcagagttaa acggcaggct cacaacctct ttcttaaacg
    32821 gtgttcaaaa gcttgcatct gcggtaatac gcccaatcaa acgaaaaata tgagaagcta
    32881 tttttgtttg gctgttctta ttacttgatg caggacagct ttttcacaac ctctgattca
    32941 cggtgttcca aaagtagctt cttcgaaaaa taagtcgaaa tttcacaaaa atttgagaag
    33001 caattttcgt acattccttc ttatttcttg aagctgacca cttctgttac aacctctttt
    33061 ttaataacca ttctaaaaag ataaagttcg ttttttaagc gtttttataa aataaaaata
    33121 aaaatcattc gattttattt gaaatatgta tctattattg atacaatggt tcaggattaa
    33181 ataatataga acgaggtgtt cacatgtcat ctgtagtagt agtaggtacg caatggggcg
    33241 atgaagggaa aggaaaaatc acagactttc tcagtgaaaa tgctgaagtg attgcacggt
    33301 accaaggtgg cgacaatgca gggcacacaa ttaagtttaa cggtgtgact tataaactgc
    33361 atttgattcc ttctgggatt ttttataaag acaagatcag tgtgatcgga aacggcgttg
    33421 tagtcaatcc taaatcattg gttaaagaat tagcttattt acatgaaaaa ggtgtagaaa
    33481 caagtaattt gcgtatttct gaccgcgcgc acgtaatctt gccttatcat atcaaattgg
    33541 accaattaca agaagatgct aagggcgaaa ataagattgg tacaacgatt aaaggaatcg
    33601 gacctgccta tatggataaa gcagctcgtg taggtatccg tattgcagac ttattagata
    33661 aagaaatttt tgaagaacgt cttcgtttga atctagatga caaaaaccgt caatttgtaa
    33721 aaatgtttga ttcagaacca cttgattttg acgatatttt tgaagaatat tatgaatacg
    33781 gacaacaaat caaacaatac gtcacagata cttccgttat cttgaatgat gctttggatg
    33841 caggcaaacg cgtgttgttt gaaggcgcac aaggtgtaat gctggatatc gaccagggaa
    33901 cttatccttt tgttacttct tctaacccag tagccggtgg ggtaacaatc ggaagcggtg
    33961 tagggccttc aaaaatcaat aaagttgtcg gcgtctgcaa agcctatacg tcacgtgtcg
    34021 gtgatggacc atttccaact gaattatttg atgaaacagg agaacaaatc cgcgaagtag
    34081 gacgagaata cggtacgaca actggtcgtc cgcgtcgtgt aggctggttt gattctgtag
    34141 ttatgcgcca ttctaaacga gtttcaggta ttaccaacct atctttaaac tcgatcgatg
    34201 tattaagtgg attggaaaca gtaaaaattt gtacggctta tgaattagat ggcgaactaa
    34261 tctaccacta tccagcaagc ttgaaagagt tgaaccgctg caaaccaatc tatgaagaat
    34321 tgccaggctg gtcagaagac attacaggat gcaaaacact tgcagaactg ccagaaaacg
    34381 cacgtaacta tgtacgtcgt atctcagagc ttgttggtgt acgtatctca acattttctg
    34441 tcggacctga tagaacacaa acaaacatct tagaaagcgt ctgggcgcaa atctaaggat
    34501 aaaaacgacg actgaatcag gacgttctta ccagagcgag tcgaagtgtt tatctatacg
    34561 ataataataa cttgaagagg tagtgaaaga gacgtttagc cttattgccg ataggctgtc
    34621 tcttgaacac tgtttattca gaataaggga ctgtgacaaa aaccgtgtca cagtcccttt
    34681 ttccgaacaa acggtgttca aaagcttgca tctacggcac taagcccaat cagatgaaaa
    34741 atatggagtg ctatttttat ctgattgttc ttactgcttg atgcagagca gctttttcac
    34801 aacctctcca ctaaacggtg ttctcctgcc aactcctcgg tcacaagtca caatattcaa
    34861 caaacatgag aagctgtttt ttgaaattgt tccttgtgac tcggagctaa acggcaggct
    34921 cacaacctct tggtaaacgg tgttcaatca gctgaccctc ggtattagct caaaaaacgg
    34981 caaaatatga ggaactattt tttccgtttt tttctctaat actcaggtca aaacgctgat
    35041 ttcacaacct ctgattcacg gtgttccaga agtagcttct acggaaataa gccgaaattt
    35101 cacaaaaatt tgagaagcaa ttttcgtaaa ttccttctta tttcttgaag ctgaccactt
    35161 ctgtcacaac ctcttatttt gattagaact tgcgaaaata aaccggttaa agtgtgtcta
    35221 gcgcaagaga tttgctataa tagacgataa gggtaaaatg taacgagaag gggttgaaaa
    35281 atgtgtatca aattgtaaca gattcttgtt gtgatctgcc ataccatgta ttagcaaaag
    35341 aaaaagttga ttttttatca atgaatctcc aattgaatga tcaagagtta gtagatgacc
    35401 tcggaaagac attcaattat gaccgctaca tgaatcagct gaaaaatggt gcgatgccta
    35461 cgacatcaca aatcaatgtt ggccgatatt tagaattttt ccgttcttat gcggaaaaac
    35521 agattcctgt tttatatgtg gctttttcca gtggattaag cggctcttac agtagtgcgc
    35581 ttcaagcggt tgaattgctg aaggaagaat atgaagaccc tgagatctat gtttttgata
    35641 caaaagctgc aagtattggg gaagggcttt tagtattgga agctgtaaga ttgaaaaaag
    35701 aaggtaaaag catcgaagaa accctagagt ggctggaaag taattatttg aaagtccatt
    35761 catgggtaac agtagacgat ctgaaatatc tagaacgagg cggtaggatt tccaaagcaa
    35821 gtgctactct tggcagtcta ttgagtgtaa agcctattat tacggtggat aaagaaggaa
    35881 ggctgacgaa tgttgacaaa gttcgaggaa gaaacaagtc gatccagaca atcgtcaatg
    35941 agacggtaaa aacaatcgtt gcaccacttg atcaaatcgt ttatgtggct tacgctgggg
    36001 atctagagag cgcggagaag gcaaaacggc ttttggaaga gcagataaag atgaaagatg
    36061 tgaagcttta tcccttagga ccaacgatcg ccagtcacac aggctatggc tgtatcgcga
    36121 ttttttcgat gggaatcagt cgataaaagc agtaactcat tctgtaaaaa agcccagaaa
    36181 ttgattgtaa caaaaacagc gactcttaaa agatagatga gcatcctatc tcttagaggt
    36241 cgctgttttt ttatttttta agctaaatag gccattatgc ccataactcg ttcaattgtt
    36301 tttgaatatc tgcattttcc aaaaattcat catatgtcgt atcagctcga tcgatcacac
    36361 ctttatccga aacggcaatg atgcggtttg ccaatgtttg gataaattga tggtcatgtg
    36421 acgcaaataa gattgagcca gtaaatgcca tcaagccgtc attcaatgct gtgattgatt
    36481 ctaagtctaa atggttcgtt ggatcatcta atacaagtac gttagctttc gaaagcatca
    36541 tttttgaaag catgcaacgg actttctctc caccagataa aacattcact ggtttcaata
    36601 cttcttcacc agaaaacaac attcttccta agaagcttct taagaaggtg ttatcatctt
    36661 cttctttact tgcatattga cgcaaccagt ctaaaatcgt tagatcagta tcgaattctt
    36721 tcgttgtatc ctttggtaaa taagaattac ttgttgtcac accccaacgt actgttccag
    36781 tatctggcgt aatttcaccc atgataactt tgaatagcgt tgttgttgtt atatcatttt
    36841 ctgcgacgaa agcgaccttg tcttctttgc tcaaattaaa agatatatca tctaaaattt
    36901 tctttccatc aatcgttaca cttacatttt ctacctgcaa taagtcgttt ccaatctcac
    36961 gttcaggttt gaatccaacg aatggataac gtctagaaga aggttggata tcgtctaaag
    37021 taattttttc aagcattttt ttacgtgaag ttgcttgttt tgattttgat gcattcgcac
    37081 taaagcgggc aataaattct tggagttctt tgatttgttc ttcttttttg gcatttgcgt
    37141 ttgcttgaag tttagccgct agttgactag attccaacca aaaatcataa tttcctacat
    37201 aaagtttgat tttaccaaaa tctagatccg ccatatgtgt acatactttg ttcaaaaagt
    37261 gacggtcatg ggatacaacg atcacagtat tttcaaaatt gatcaaaaat tcttccagcc
    37321 aattgatcga ttggatatcc agaccgtttg ttggttcgtc tagcaaaaga acatcaggtt
    37381 taccaaatag tgtttgtgct aataacactt ttaccttttg tccaccagtt aattcactca
    37441 tttgctgatg gtgcaattct tcagggatgt tcagaccttg cagtaaaaca gctgcttctg
    37501 gttcagcttc ccatccatta agctcagcaa attctccttc taattcagct gctcgaatac
    37561 catcttcgtc agtgaaatcc tctttcatgt aaatcgcatc tttttctttc agcacttcat
    37621 acagacgctt gtgtcccatg atgactgttt caagtacagt atagtcttca tagtcgtaat
    37681 ggttctgttt caatacggcc atccgttcat ctggtcccat agtaacggaa cctgtggaag
    37741 gctgcagatc ccctgataac actttaagga acgttgattt acctgcacca tttgcaccaa
    37801 tcaagccata gcagtttccg ggggtaaatt taatattcac atcatcaaat agtttgcggt
    37861 ctgaaaagtg caaactcaca tcatttacag taatcaattt ttttcctcac ttttatcatt
    37921 attagttttg acaagtctta tagaattata taggggaaag gtaaaagatt caaggcaatc
    37981 gaacattctt tgtgtttcac gtgaaacaga atgaaaaaaa taaaaataaa agcggagcga
    38041 aaatagctac tataggattt attagtttgc aacagcataa tttttgacgt tatttataag
    38101 agggagtact ataaaactgt aaaagaaatg aaagaaggat tgaaaatgga tgaaaaaaga
    38161 accatcgact ggggctcatt gattttggga attttatttg tacttgtctc attgttatca
    38221 tttcaagacc ctgtcggaaa tttagttgca attgtagtag tctttgcgat ttttgccttt
    38281 attaaaggga tatttgaact gtttgtacgg aacagattaa aagagctaac aggatataaa
    38341 ggaaagatgc ccttaataat cgggatcatc gatattctag ttggcgtctt tttcttattc
    38401 aatattggtg caggagtcgc agcattgcct tttgtttttg cagtatggtt tattgctgat
    38461 tcagttttag cgttatttac tgctgacttg gcaagaggag taagtgaagg atattattgg
    38521 tttacgatca tcgtcaatat tttaggaatt ttattaggaa ttttcttatt gtttaatcca
    38581 atttcttctg cgttgacatt aagcttttta gttggattct attttatgtt atttggtatc
    38641 acacatatcg tctatgcatt tagataagta aaatcaaaca aataaaaaag ccggcttccg
    38701 attacagttt tactgttgta attggaagcc ggctttttta tcatggacaa atatgcacga
    38761 ggtgattttt aggtgtcgag acaaatttat gcaaaaatgt gagaagctat atacacaaat
    38821 tttatcttaa tactcgaagc atagcgcagt tgtcacaacc tcttttcata taattcattc
    38881 aatactggca aatcatggac ttcatatttt tctttgaatg cttggatttc ttcttcagaa
    38941 tattttcttg gatctaaatg cagatcttct actggcaatg ggcgcttgtt attgatcttc
    39001 acatcgatta ctacaggacg atctgatttt gcagctgcat caaaggcaaa tcgaagttgc
    39061 gagtattctg tgactgtaaa gctatttgcc ccgagcgctt ctccaacttt accgaaatct
    39121 gcatcttcta aaaatacacc aaatttcttt tgttccgtat cttcttgttc tgcttcgatg
    39181 aaaccaaaag aatcattcga aaagacaaca ttaataattg gaagctgata tttgacttgt
    39241 gtaatgatat cttgcatgac catagcaaac ccgccatcac cacttaaggt aaatacttgt
    39301 ttttctgggt agcttagttg tgcggcaatt cctcctggca caccattacc catagttgcg
    39361 aaccatccag atgtcgtatg tttttgttta ccgttcatat tcaataaacg aatagaatgg
    39421 atagtcgtgt taccgacatc tgtgacgaaa atcgcatcgt cttcagcaat acgattgatt
    39481 tctttataga cagcctctgg acgaatcggt tcttcctctc gatcttcaaa agatttcaac
    39541 caatttaccc atttttcttt attttcttga tttgctaggt accagctatc agcagggcga
    39601 gcatccccta actcgacaag tctttgcaaa gctgtgtttg catcaccgag gatcgacaaa
    39661 gatgtttcat ggcgtcgtcc aaattttgac gcatcgatat cgatttggat aaattcagca
    39721 gttggattaa aaaatgcacg tccaaatggg aagtcgctac cgacaaataa gatcagatcg
    39781 gcttctgcca atgcttcatt tccgggttta gtagcgacac gtccagcaaa accaagaaag
    39841 ttttcataat catcaggaat aattcctttt gctagaacgg aagcgacaac aggaactgaa
    39901 aaatgttctg agaattcttt gatttgcgga aatccgtttc gcgttccttg accaacataa
    39961 agaactggtt tttttgcttt ttcaagataa ggcaaagcag ctagcaaatc tttttcttct
    40021 ggtaatatca cacttgtttt gtgagtgtga gcggtggaga aaggttgttc gtcaatttct
    40081 tcaaaaccaa gatcaacagg gatagtcacg atagccacgc ctttatgctc ataggcggct
    40141 ttaatggctt catctactac atgcggaaga ctttgtggtg tcatgactgt acgattgtat
    40201 acgctaacat ctgcgaaaat aggattttca tttagttcct ggaaagagtt atagttcatg
    40261 gatgtagaag caacttgtcc taagaacgct actagaggca catggtccat ctgtgcatca
    40321 tacaaaccat tgatcaaatg tgtcgcacca ggtcctgcag agccgaagac agcgccgact
    40381 ttccccgtta attttgcatc tgcagcggct gcgagtgcgc cgacttcttc atgacgaact
    40441 tgaatgtagt tgatttcggt tttttcttga tatagcgcat ccataattga attgaaagat
    40501 cctccgggaa tgccgtaaat atggtcgata ccccagcttt caagaacttt taccattgcg
    40561 attcctgcat tgatttttga catggtgttt cactccttta gcaatgatga tacataaatt
    40621 ttttgtatct agagtataga actttttatc gaaaatccca actaattcgt cttttcacaa
    40681 aaatgtagtc atgtttttgg gaatatgcta gagtagtaca tagatagatt caagagaggg
    40741 gaatggcatg gttgaatggc tattgagact tgaaccttgg cagcaagcac ttgctgggac
    40801 agcttttact tattttatga cagctcttgg tgccgggttg gtttttttct ttaaagaaat
    40861 caaaaaagaa gtgctaaact tgatgttagg atttgcttct ggtgtcatga ttgctgcaag
    40921 tttttggtct ttgttagatc cggctattac aaaagcagaa gaaaatggag atattgcttg
    40981 gctagttgta agtattgggt ttggtttagg cggtgtgttt ttatatatgg cagataaaac
    41041 actgccccat atgcattttg gaccacaaca tgaagcagaa ggattgccta cccatttaaa
    41101 acggacgatc ttgcttgttt tttctattac attgcataac attcctgaag gtttagccgt
    41161 gggggtagca ttcggtgcag cagcaactgc ggataatccg acagccgcta tattagccgc
    41221 tgtttcggtg gcgctaggta ttggtatcca aaacttccca gaaggagcag ctgtatcaat
    41281 cccgttgcga caagaaggtc tgagtcgtaa aaaggccttt gtttacggac aagcttctgg
    41341 aatcgttgaa ccaattgctg gagtgattgg agcgctacta gtaacgaaag tggagctgct
    41401 gcttccttat gcacttgctt ttgccgcagg agcaatgatt tatgtcgtgg tggaagaatt
    41461 gatccctgaa gcacagcaga cattgtccag caaacgtcat tttgcagttt ttggcgtcat
    41521 gagtggattt atcattatga tgattttgga tgtggcatta ggataaataa aaaaaatata
    41581 tatgatatat caaatagggc cgcgaactta tatcgcgacc ctattttttt agtaagttat
    41641 atcataatga agtgaatggt atcatacatt aataatagtt ttttctatgt gtatttcctt
    41701 tgatccagcg aacaagccag atgataagtg cgattgggat tagaactttg accgcaaacc
    41761 ataaaagccc gcttaggaca ctgacaaaaa gactgatgac gaagctagct gcaattagca
    41821 ctaaaagaac catgaagata tttaagaaca tatttttttg acgcatacaa aaccctcctc
    41881 ttgttcattc tttactatag aaaaagtata acagggattg tttaaaaaca cctccaactg
    41941 aagactgatt tttacttcat ctacttaaat gatcaaacaa ttgctttttc tctggtttat
    42001 catctaaaat agagcggaaa aggaggagaa tatcatgcct aaaaatcgtc ttgaagcatt
    42061 tacagatgct gtaatcgcga ttatcatgac tattttagtt ttagaacttc atgaacctaa
    42121 cggagacacg tgggaggcgc tcgctgcatt aggttaccga ttttttatct atattgtcag
    42181 ttttatcatt ttagcgattt attggaacaa tcatcatcat ttatttcaag ttgtacataa
    42241 gataaatgga cgggtcttat gggcgaacag tttctttgtt tttgcgcttt cgctttttcc
    42301 gtttgcaact tcatggatca gtgagtacat caatagcctg gctccagaaa tgacttatgg
    42361 ttttgttacc ttgaccgcta atattgcgta ttatatcttg gcaaaagaac ttgtcaaagc
    42421 aaataaaggc cacgagaaag cattgaaggc gatgttgaat aattacaaga aatcgtatct
    42481 atcgattggt ttgaatgtgt taggaattgt cttagggtat ttagtagcgc cagtagccgt
    42541 gctgatcgca aacatcgtga ttctagctgc ttggatcatc ccaagtcgta ccatcgaatc
    42601 acaatatcgg taaaatgatc cgtgtttaaa atttaagaga aaaatataga aaaaataaat
    42661 aaacgatcaa atatccgagt gatactagta ttcaaagagg gatgcagatg gatcaaaaaa
    42721 gaattcatgt aggactgatt actagttttg tcacgatgct tatttatttg gatcaaggtc
    42781 atttgacttg gacagtagtt ggtgtcgtag gatttttgac attattcaca gcaataaaaa
    42841 aataaacatc tttatgtaat ctgatgttct atctatttaa gaaaagcatg tttacagcag
    42901 tatgattctg ttgtaaacgt gtttttattt gtggaaaatt taatttttag aaaagtgtat
    42961 cgaaaaatag atagttagtt tttccacagt ggataacttc gtaagagata aaaataaaaa
    43021 attagtcaaa gaagggcgta tagatttctt ttgataggag atatacaaca gaaatgaata
    43081 aatattaacg tgttttcaaa cagtataaaa cggtgtggtt tttggaataa aaaaataaca
    43141 tatctcattt tacacttttg ttattttata cttaaaaaat aacgacacag aaaataccgt
    43201 gtctcagatt tctctactac ttctaaaaac tactgttttt ttcctttgaa atgccttcaa
    43261 aaagtaggat caggcagaat atactggcag aatcaaggag aagggagcct aaataaggag
    43321 aaaaaccata gaaaatataa agtaattact tataaaacaa gctttttata gaaaaataat
    43381 atacctgagt agggtataaa ttaagacgga attcctttct agattgagat attgactagg
    43441 aagaatgtta agattttaag cctttaagct aaaaaaaaac cctttttgtt aaataagggg
    43501 aatatagcct gtcagtttca aactgcaagt cgtcctgctg caataatata gtagattaga
    43561 gatgaaaata gattttttta aaccaatgac tgaataaaaa gaccgtcata gatacacatt
    43621 ggaatgtgtc tattacggtc tttttttacg aacgatttta ttgaagacgg acagttcggg
    43681 tcaaaaataa aaaagctacg atcagaaata agaataaaat gtatcccaaa ataatggcta
    43741 gacggtctaa cttatttgtc gatagatgtt tgtttagaag ttgataggcc cataaaccta
    43801 tcagtcctcc tgttgtatta gttatcaaat cagtgatgtc cgctacgcca ataccgaata
    43861 ggaattgaat caattctgcc aagaagctta caaggaaaat aatccctaat tttttagaaa
    43921 aagaaagtct cttgaaattg acattcaaaa gcaccccaaa aggaaaaaag acaatcaagt
    43981 tataagtggt ctcacgtaat accgtcgtat tttcaaaaga aaaagtagaa aaagggacga
    44041 gattgacatt gctgtaagaa taagtgagaa attgtggaag attaaatgat agcttgaata
    44101 aaatcaacca taatagaaag aataaataaa tccctaataa aaattttgat acataccgca
    44161 tagacatctc ctccatttaa aaagtatacc atcgaaaacc gctgaaaaat cataaaaaag
    44221 tatgaagttt aaggaccaac gtagttatcg tacgaaaatt agaagctttt ttttgttggg
    44281 aatccggttt ctttaacaaa gctaagatag cgagttgctt ggaaaagttg ctatcttttt
    44341 tctgtcaaaa cgactcggaa tgttcgtttt ttgttctaat ttctccaagt tgtttacttt
    44401 ttgatactaa gtttatgaaa aatcaagaaa tagttgttat actaggtaat gctgacaaac
    44461 gggattggca tttcatcttg gttcagcttt ttttccaatt actaggaagg agggatagat
    44521 tgttcaagac ttattttcgt ttcaataaaa tacaagataa tccttttcgt atcatgaatc
    44581 tgatgctact tatctttatt gtattatggt taggttacat aaatcatgat tttttgattt
    44641 caagtttttc atcattaggg atctttactt ttttctatta tcaaaacata ccgatgaaat
    44701 atttgctgaa acgtatgttt ctgatcggtt gcggactgtt ggttgctttc gttttgggga
    44761 tcttatcgac ttatgtttta tggcttgaac catttgccgt agctttggtt gctttttcca
    44821 gcagattcgt gttgcgatta ttccatattt ctaaaccagg tggcttgttt tttgcgatgc
    44881 tttctgccat gggaacgagc atgcagctgc caatcgctca attaccgatc gtctcacttt
    44941 atttttttat gggtgtcgtt tttgccctga ttgcggcagt gattacaaaa ttactggatt
    45001 cacggcctga gcagacaatt gaaaaagcaa ctttaaaaga aagatttcac gaagagcctt
    45061 tagtgatcat tgattctgtt ttctacagcg ctgccttatt tctttccgtt tatgtcagtc
    45121 acggcttgaa tctgcataat ccttattggt tgaccttgtc atgtgcatcg attttgctag
    45181 cagaaaactt ggatgcgatg aagcatcgac aagtccaata tctgattgga tcgatgggtg
    45241 ggttatgtgt gtcggcattc ttgtcatttg tgccgtttac gcagttgcag accatttttc
    45301 tgatcacttt tctatatgga atcgcacaat ttctagttgc tagaaattat gcagttgcta
    45361 atatttttct taatccgatg gcgttgatgc tatctacact tattcgtgga gcatacttga
    45421 tttctttgat cgaatatcgt tttttaggga tcgtcatagg aagtttcatc ggtttaggtg
    45481 ttgcgtgggt aatgacggtt ggtttgcaac attatttaac ggttgttcgt caaaaattag
    45541 aatagaagga caaatatatg tgccaaaaga ggttatgaca agatttttgt cacaacctct
    45601 aattcaaggt gttcaaaagc cagattctca gcattaagtc aaattcacac aaaaatgtgg
    45661 aaaggaactt tcaaaaaaat tttatattta ttctatcaaa aaattttgtt tatgatggta
    45721 actgaataaa ctttcctgag atggtcaatg ctttccttga aagtcttaca gatattcttt
    45781 cttcatagaa agtttaagtt ttatagttag tgtacaataa aagtatgttt ataccatatg
    45841 gtgtccggat aatcagtcat ttaaacaatg aggttcaaag atatgaaaag gggaaatttg
    45901 atgaagaaaa taagcaatga aatccaaatt ctggcagaaa ctttaactct tcccaaagtc
    45961 gttatagagc aaatgattgt acaagcaaaa aacatccttg atgaggtgtt tgagcaatat
    46021 agtcatgaac taatggatcc taataaagca aaggcgactg caaagaaaat agacaaagtc
    46081 tatgaagagg aaccttttgc agcattagct atttatctat atgcagcttc tcaaagttgg
    46141 aaaaaaattt atcaaccatt gaagattcca agaactatct atttggcaac aatgaatgct
    46201 tttactagat ttattcatga acatttccaa gtaacaggaa gctatcgctt tgaccgtggt
    46261 ttttggattt ggcattacac tagtggcttg atctttcgga ttggtgaatt ggagtacgaa
    46321 atgacatatt ttccgaaagg gtacacggat ctaagattag aaggaaagca gtgcctttct
    46381 cttcatattc cttccgatgc agatttatct cagaataaga taagagatag ttacgaaagt
    46441 gccattcgtt tttttgaact ttattttcct gattaccatt accaagtgat gtacacagat
    46501 acttggttac tatcacccaa tcttactaaa tggttgaaaa aagagtcaaa aatctgtctt
    46561 tttgcagccg attatcgatt attatcagtt gatgaacagg acgatagtgg agtcccttgg
    46621 atctttggac gagtagatgc ccaaatacat gattatccag aaagtacgag tttacagcga
    46681 caagcaaaag agcaattgct tgcaggcgag cacattggct ctggcttagg tattcttact
    46741 tcataagttt agtacttcga aatagtttaa aagagcgtga gacaaaagta aagaacactt
    46801 ttgtctcacg ctctaaacac gtataaacgg cggaagcaga agcaactcct tcggaaataa
    46861 gctgaaattc acaaaaattt gaaaagcaat tttcgtgaat ttcttcttgt ttcttggagt
    46921 taaacgcttc tgtcccagcc tcttttttag tgttctatcg aacacacagt acgttcaata
    46981 ggtaaactag ctataacaat agatattaaa gttaacggac aagagggcct tttttaggta
    47041 gctaaaacgt aataatgaaa atttatttcc agagatagga gtcaatcagc tagtctgatc
    47101 gactgtttta acaagttgac tttcatttta acttttgata ccatttaaaa cacaaatcgt
    47161 aattgtttcg atttgtgttt tttagcatga ctacaatcaa agaagaaagt gggtcgtcca
    47221 tatggaaaaa acagatatct caagtgcata ccgccgcttg aaaagcccaa atatcaaaac
    47281 acgaaaacgt gcgctgaaga tcatcaaaga tgtgaaacgg aatagtggga aaaggtaaga
    47341 agaaggaaac ttaattaaaa aaatagccga aaaacgtttt tcggctattt tcaataatcg
    47401 gtttttgtgt aaggtttccg aaagaactgc tgttgatttt ccatttttaa catatgataa
    47461 attggtagaa tctttctttt caaattgata ccattcccta attccagtta tatagttaac
    47521 tacagaacca caaagcacgt acgtttataa aagtattatc tgtagttatt tttcaattcc
    47581 ctttcaacct cttattttga ccagtagtat tgatcacttt accttttaac acctttgttc
    47641 gtttttgaaa catttttagt caagaatgga aacgtaacta cataatcaaa ggttttgcga
    47701 aatatttcat gaaatatttc atgtagaagc gagcaatacg gttgcaaata accattatcg
    47761 tttaataagc agttacgaaa gctcccaata tctctaacgt tcagctcact ccatttcttt
    47821 tcttcaaaaa aatcagtgat tcgtatctct ttctatttgt cgaaaaagtt aactttaaaa
    47881 agtaacgccg aaaaaatatg caaaaaaata aaaaagcagt tactattgct agaataacat
    47941 caaggaataa taagttttgg ttttcagata atagtcgata agttgtgtat tggaatttta
    48001 gatacagtaa taaagtattt ttcatgaaat tttgtgagaa tcactattac aagtatcttt
    48061 aataaaatta atggttaagg aggaacttaa agtagaatgt aaatgaatag ttgtagtcag
    48121 tcgattgtga tactagactc aaagttgcag gaataagttt ttcaatttgt gattggaaga
    48181 taaaaaatga aaaagaaggg ctttttttta tactttgttg attgtagtgt ttattttccc
    48241 tctgtttagc caagtaacat tttctatgac tcaaccagtt tcaagtgagg aacatgataa
    48301 cctttttcgt gctacagaag agtttaagaa atatcaggaa aatattgttc cggagactcc
    48361 attagctagt gagccaatta ctgatattga tggaaaccaa ataggatggt atatacagta
    48421 cgaagttatg gtggtaaata atgactcaat agtaaaaaat acagtaggct tagagctaac
    48481 accgattgaa aaggtgagtt cattgttaac gtatatttat actgatgaaa gtgacgagac
    48541 tgagatcatt ttaacggatt actcaaaaat tgctactgat aaaaagtata tattgtggat
    48601 gtagacacta gtgaaatact ttatgatata gaaattgatg aaaatttact agatgtagca
    48661 caagaaatcg atcatcaaaa gcaggaagct attcgatatg ctggtagaaa agggaaaaga
    48721 aaatatttat tacgtgaatg tagcaaaagt tagagaagat gaaaatgagt ggaaagaatt
    48781 caagagtcgc tactcaatta actcgactcc gacatttaca gtttacagag aaggatcgat
    48841 agaaaaaact gttttttgga ctaaagaaag tggaatgtct ttagctgaag tagaagagtt
    48901 tttggattat gttagtatgc aacagtaagg gagttcttat tatgaaaaat tttgacacat
    48961 attatgttat tgttttttcg atatctttgc tgttaatatt actaacttta atgcagtata
    49021 aagagtatcc agagtatttt attttaactt ttgtatattt agtaagtagc tacacacttc
    49081 tatataaatt cagaagttct tctagagttt ctaaagtttg tttcttaatt agcttattga
    49141 ttctataata tttttgattt atataggaaa ttaaaaatat tatagaatca acactcagag
    49201 aacgggttgg tttttaatag atttaataag tactgataat gaaatttctc ctggttggga
    49261 aaacgaagtt ggttaccctg tagaagaatt ttttcaagat tactttgcgg agtatgccga
    49321 taggataatg agagattacg taacagataa aactcaagaa gtcatcaatc aatcccagtc
    49381 attaaatgaa ttatctgata aggcgaaaga agaagcagtt gccattattt cttcagggat
    49441 tagtgactat attgatatga gtggtgaaat caattatggc gataaagaca aaattgtacg
    49501 catgataaaa gcttttatca aaacttttga tgtgaaggca gatcttaagt ttaatgatac
    49561 ttacctagta ggaaaattaa ttaatatcct tgggacagag aaagatacgg aaacgtttat
    49621 ttcctctttg tctatgttgt ttacagataa gcatttttca actcagcttg gtggagagga
    49681 actagtggaa atcttttaac cattacgccc agcattaata aaagtatatc aaaaaagtac
    49741 tcctgatgat ttttaagatt ggtttgagaa ataatgtgaa aacactattt ttaatgttaa
    49801 ttatagatag agatgaacgc gtcatatggt taaaagaatg aaaaagtcaa agatacactg
    49861 ctatatttca ctaaggatat agcagtgtat ctttcatgtc gtttcactgg cagtttttta
    49921 taaaaggagg tgtgcatttc agttgctttt ctttggtagt tagttgaatc gtttaagaat
    49981 taacggatgt ggcagacagg tgctctgtcc aaaaaccagt aaaatctttg atggttccat
    50041 ctttatttag ctgtgcctgt tcaaatactg ttttgttttt accgaatgga tcaattgcaa
    50101 taattgttcc gatccccgca cgtttggcag caagtaatcc tgagtaagca tcttcgataa
    50161 caagacaatc agccggagct aagctcagtt tgtctgccgc tttaagaaaa atatccggtt
    50221 gcggtttccc agggaaagag ccgtcgtcat agacaatctt gtcccagtca aaccagcggg
    50281 ctaaatcgaa aatatcaaaa taaaaagcaa cattctcttt gacagtagcc gtggcaatcg
    50341 ttaatggaat ctgttggtca gtcagctggt caagagtcgc ttcaagccct tttgtcaact
    50401 gaagctcgtt ttcattttgc aagcaaagca tacgataata gctttctttt tcttctgaca
    50461 atacggcgat ctcagaggcg gtcaaatgct ctgaaatgaa atgtttcaaa atctccgtat
    50521 tcgtccgacc atgaatattt tttaaaatat cctcgtctga taaaccatct tttgtatgat
    50581 catgtatcat atgcagccaa gcagcttcat gcagatgaga gtccaaaaac attgttccgt
    50641 tgaaatcaaa tataatccct ttcatagtta cgctcctata gtggtatttt cggttgaatc
    50701 agcaatttgc agatcgacat attgtgcata gtgctcttga acctcccgcg agatctggcg
    50761 atccgtaatg agcagatcga aatcatgcaa attataaaac acataaaaat catctcgatt
    50821 gaatttttta ttatcaacga gtagatattt cttacgggaa ttatttagag cgatctgctg
    50881 tgcttctcct tcttcggtac tgtaagtaga gatcgcttcg ttgtgaacgc catttgaact
    50941 gataaatgct tttgtaaact ttagtcttct taaattgtcg ttggtgatcg gtccgacaaa
    51001 tgcgccggta tttttccgga aatcaccgcc aatcagtaga atttctggtc catctgcttg
    51061 agcaagaata tcaaaaactg gataattatt tgtaatgatc cgaattttct tgttcagtaa
    51121 atgcgtcgcc aatagttcga ttgttgtacc tggtcctaag aaaatcgttt ctccctcgtg
    51181 aatcaaggag gctgctgtgg cagcaatttc ttttttttct tgaatctgca gagtggcttt
    51241 ttcagtgtga gaaagttctt gatctaaagt gtaggaaaga ctttgagccc ctccatggac
    51301 acgcagcagc ttgcccgatt tttctaattc atctaaatct ctgcgaacgg tcatatcaga
    51361 aacatctaat tgattgatga tttcattaac ggtaaggatt ccttttttat tgaccatttc
    51421 tacgatagta agcaatcttt cttttttcaa cattgtcttc acctctaatt taaggataat
    51481 ctatcatata aacggacaac agtcaatcta attcgaacaa aagtaaacat ttagggtggt
    51541 ttttatgttt gttacaatag attttattgc tgttttctgg tttttatgat tatttgtgtt
    51601 tgtttttgtt gacaaatgtt ttggatgcgt ttacaatgca atcagttaga aagagcgaaa
    51661 actgattata gatttgagga gagatgtaca tgcttaaatt accagaagat tttatttttg
    51721 gcggagccac agcagcctat caggttgaag gagccactaa ggaaggtggc aaaggcgctg
    51781 ttgcttggga tgacttttta gaggaacaag ggcgattcag tcccgatccg gcaagtgatt
    51841 tttatcatca atatgcaaag gacattgaat tgtgtgaacg ttttggtgta aatggtctaa
    51901 gattatccat tgcttggagc cgcatttttc ctgatggagc tgggaaacca aatccagaag
    51961 gaatcgcttt ttatcatcgt gtgttcgaag aatgtaagaa aagaaacgta acgccgtttg
    52021 tgacgttgca tcattttgat acccctaaac gtttgtttga ccatggagat tttttgaatc
    52081 gagaaacaat agaagcattt gtttcctatg ccattttttg ttttcatgaa ttcaaagaag
    52141 tcaaggtgtg gagtaccttt aatgaaatct atccagttgc aaccaatcaa tatttgttag
    52201 gtgttttccc accaggaatc aaatatgatt ttacaaagat cgtcgcctgt cttcataata
    52261 tgatggttgc tcatgcccgt gtagtgaact atttcaaaga aaacgaactt ccgggtgaaa
    52321 ttggtgtagt tcactcatta gagacgaaat atgcggcaac agacgcgccg gaagataagc
    52381 atgctgcctt tttagacgat gcattgtcga tccgtttctt attagatgct acctatttag
    52441 gctattattc aactgaaacc ttgactgctc ttgatgagat atgtgaagca aatcaggcca
    52501 gctatcattt tcctgaagaa gatttcgttg aattgaaaaa agcatccacg cgtaatgact
    52561 acttagggat caatcactac caatgccatt ttgtcaaagc ttacgatgga gaaaatgcaa
    52621 tccatcataa cggtacgggt gaaaaaggga cctctgttta taaagtgaag ggaatcggag
    52681 aacgtattta taaagaagga attcctcgaa ctgattggga ctggctgatt tatccagaag
    52741 gtctatatga cttgttgctg cgaattaaaa gcgattaccc acattacaac aaaatctata
    52801 tcactgagaa cgggatgggg tataaagatc agtttgaaga tggcattatt atggatcagc
    52861 cgagaatcga ctatttgaga gtctatttgg aatccttaag caaggcgata acagccgggg
    52921 taaatgtgaa ggggtatttt ttgtggtcgc ttatggatct tttctcatgg acaaatgggt
    52981 ataacaaaag gtatggcttg ttttatgttg attttgaaac ccagaagcgt tacccaaaag
    53041 aatcagctta ctggtacaag ttggtcagtg aaaccaaaac gattatttaa taagtgataa
    53101 tggaggaaga aaagatgaat aaagaggaat tacaaatgct tggttttgag atcgttgcat
    53161 attcaggcga cgctcgcagt acattattga aattattgaa agaagtaaga caaggaaact
    53221 ttgaacatgt tgattcggcg ttgaaagaag ccgacgaaaa tttaaccctt gcacataatt
    53281 cgcaaacaaa aattttagcg gaagaagcat ctgggaaaga gatggagatg ggattcattt
    53341 ttatccatgg gcaggatcat ttaatgacca ctttattgct gagagatctg attcaagact
    53401 ttattgtact gtacagacag aatcaaggat aggagaagaa cgctatggat ggaatcatta
    53461 aacaaatcga aaaagggaaa ccattttttg aaaaaatctc acgtaatagt tatttaggag
    53521 ccgttcgtga cggattttta acagcgatgc cagctatttt attttcaagc attttcattt
    53581 tgattgctgc ggttcctgag atttttggtt accaatggcc tgaatctgtc tccacatggc
    53641 tatggaaagt ctataattat tcgatgggtg ttgtagggtt actcgtttca gcaaccactg
    53701 ctcgctgctt ggctgattcg atgaatcgtc gcttaccgaa aaacaaagta atcaacacca
    53761 cctctgtgat gctggcctct gtggtaagtt tcctgttgtt aagcgtctct ccgattgaag
    53821 gtggattttc aacggaatat atggggacaa agggactact ggcttccttt gtcgctgcat
    53881 ttttaacagt taatttatat aagttttgtg tgctgaaaga tattaccatt aaaatgccta
    53941 aagaagttcc tggaacgatt tcgcaaacct tccgagatat ttttcctttc tctttttcag
    54001 tatttgcggc cgttttaatt gatttaggca ttcgacaaat cttccaaatc tcatttgcag
    54061 aagcaatcat tacggtgctg cagccgctat ttacagcagc tgacgggtac ttaggaatcg
    54121 ctattatctg gggagcgatg gcgctgtttt ggtttgtcgg tgttcatgga ccgtcgatcg
    54181 tggagccggc aattgcggca attatctatg ccaatgtgga aaccaatctg caattgttca
    54241 attccggtga acaagcttct aaagtactga cggtgggttt agggaatttt gtaggaacta
    54301 tgggaggaac tggggcaaca ttggttgttc cttttatctt cctactcttt gctaagtcta
    54361 agcagttgaa ggcagttggg aaagcttcct ttattccagt aagtttcgct gtcaacgaac
    54421 cattgctatt tgcggcaccc atgattttga acccttattt ttttattcca tttttgttaa
    54481 cacctgttgt aaacgtttgc ctgttcaagt tttttgtcga tgtattgggc atgaacagct
    54541 ttatgtacgt tttgccttgg gcaactccag caccgatcgg tttggttcta ggaacgggca
    54601 tgggtatctt agcttttgtt ctagcagcgg ttctaatcgt cgttgacttc ctgatctatc
    54661 taccattttg caaagcatac gatgctgtct tagtagagaa agaagcacaa aaagcagagg
    54721 tgatcgcaac cgaggaaggt gcttctgccg atgtacgtga ggaagtacct gtggcagcga
    54781 gtcaagttat cagcgatgca aataaagaaa tcaatgtgtt ggtactttgt gctggcgcag
    54841 ggacaagtgc gatgttagct aatgctttaa aaaaaggtgc atctgaatcg aaagcaccga
    54901 tcagtgcaat ggcgggtgct tatggttctc attacgaaat gctgcaggat tttgatatgg
    54961 tggtcttagc accgcaagtc aattcttact atgatgatat caaagaagac accgatcgct
    55021 taggaatcaa gctggttgcg acaaaaggag cagaatatat cggattaacg agagatcctg
    55081 aaaaagctgt tcagtttatt ctgaaccaat ttcaataaag gaggagccat aatgaaaatg
    55141 ggaatttggt tgcgtaaagc tgttttattt gcagctgtgt taggggcttt gggggctgtt
    55201 tcaaaaactg ttgaagcatc tgccagcgaa tttattcgcg gagcagatat ttcgatcctg
    55261 tcagatatgg aaaaatctgg tgcaaaatat tatgaagacg atatttcaaa agatgcctta
    55321 gagattttaa aaaataatgg tgtcaactat gttcgactgc gtttgtggca ggatccttat
    55381 aatagtaatg gagaaagtta tggagcaggg acaaatgatc tggaaacgac gattgacctt
    55441 gcaaaacgag caaaaaatct gggacttaag gtgctgctgg attttcacta cagtgatttt
    55501 tgggttgatc ctgggaaaca gaatcttcct aaagcatggc aaggtctgac ctttgaagaa
    55561 atgaatacgg cattgtacga ctatacaaag aacgttctgt cggaaatgaa gcagctggac
    55621 gtttatcctg atatggttca gatcggcaat gaactgaata gcggaatgct ctggccttat
    55681 ggcaagtctt ggggagaagg cgggggagaa tttgatcgat tggctgcttt tttgaagtct
    55741 ggtatccaag ctgttcgaga cactcaacct aaaacaactc cagtaatgct ccacttagct
    55801 gatggtggcg atacaggagc atttacttgg tggtttgatg aaatcacgag tcgaggtgtg
    55861 tcatttgatt taattggagt gtcgtattat ccgtattggc acggttcaat gaatgaactt
    55921 caaaccaata tgaatgcgat cagccaacgg tatggtaaag aagtgatcgt agttgaaaca
    55981 gcttatgggc atacaacagc gaatgccgat actatgccaa atgcttttgg tgaagccgaa
    56041 gcagctgcgg ggggatatga accaacaccg acaggacaag cagagtattt gctggatctt
    56101 gccgatcgga ttcaggcagt accgaataat cgcggggcgg gcttcttcta ttgggaacct
    56161 ctttggtaca acggaaatgt gagttgggca acacaagcag gtatgaatta tctcagtgtt
    56221 caatccacta tgggaaacga atgggacaac caagcgatgt ttgattttgc tggaaacgcc
    56281 ttgccaagct tgcgtgcgtt taaacaagca ggggcgcaaa taaatctagt taaaaatgca
    56341 agtttcgaaa gcgatggacc aacgaccagt ccttccaatt ggcaaacctg gtttcaacaa
    56401 ggaaccgcta agggtacgat caaaacggaa gcgggcactt tttttgggga ctacaaacta
    56461 actttttggc aggatcaagc atacgaggca tcagcttatc aaaatgttag tggcataagc
    56521 aaaggaactt acacattgag tgcctatgta atgtctgggg gagagtttga tactaatcag
    56581 ttatatatca aaaattatgg tggagcggaa ctaaatactg cggttgttaa aacaagtgaa
    56641 tggacaaaaa ttacaatcaa agacattcca attacaacag gtgtttgtga aattggggtt
    56701 tatagcaagg cttcaggaaa tgcttggacg aacgttgatt ttgtttcatt ggtgaaacaa
    56761 tagactgcgg atcgtttcga ttcaagatcg gaggttccct tcagccacat cgttagcgta
    56821 gaaggcagga atcgaacctg cacctcgcct ttgccaaaaa taaccagaaa cgatttccag
    56881 tcatttttac caaaacgagt aaagcaccag acttcatcta cactttgtat tatgctaaag
    56941 agagttcaac gatttcgtaa gaagcaatga aaaaattgca aaaagttgtg cagataacat
    57001 aaagtttgtt taagaaaggg taaccttaga attccgtcgt gaatatgatt tgagcactta
    57061 gatggataga aa
//
LOCUS       DAZULR010000015        55340 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.015, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000015 DAZULR010000000
VERSION     DAZULR010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 55340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55340
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.015"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..597)
                     /locus_tag="ACG8ZV_001021"
     CDS             complement(<1..597)
                     /locus_tag="ACG8ZV_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4996377.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEA"
     gene            790..1821
                     /gene="queA"
                     /locus_tag="ACG8ZV_001022"
     CDS             790..1821
                     /gene="queA"
                     /locus_tag="ACG8ZV_001022"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HFS4996378.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            2440..5079
                     /locus_tag="ACG8ZV_001023"
     CDS             2440..5079
                     /locus_tag="ACG8ZV_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFS4996379.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(5247..5945)
                     /locus_tag="ACG8ZV_001024"
     CDS             complement(5247..5945)
                     /locus_tag="ACG8ZV_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HFS4996380.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            6162..7307
                     /gene="tgt"
                     /locus_tag="ACG8ZV_001025"
     CDS             6162..7307
                     /gene="tgt"
                     /locus_tag="ACG8ZV_001025"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HFS4996381.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            7404..7784
                     /gene="yajC"
                     /locus_tag="ACG8ZV_001026"
     CDS             7404..7784
                     /gene="yajC"
                     /locus_tag="ACG8ZV_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HFS4996382.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            8089..10686
                     /gene="adhE"
                     /locus_tag="ACG8ZV_001027"
                     /gene_synonym="adhC"
     CDS             8089..10686
                     /gene="adhE"
                     /locus_tag="ACG8ZV_001027"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HFS4996383.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            10915..12021
                     /locus_tag="ACG8ZV_001028"
     CDS             10915..12021
                     /locus_tag="ACG8ZV_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFS4996384.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            12038..13066
                     /locus_tag="ACG8ZV_001029"
     CDS             12038..13066
                     /locus_tag="ACG8ZV_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HFS4996385.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLKGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            13072..13551
                     /locus_tag="ACG8ZV_001030"
     CDS             13072..13551
                     /locus_tag="ACG8ZV_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HFS4996386.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            13567..14862
                     /locus_tag="ACG8ZV_001031"
     CDS             13567..14862
                     /locus_tag="ACG8ZV_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0031317 - tripartite ATP-independent
                     periplasmic transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HFS4996387.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            14873..15697
                     /locus_tag="ACG8ZV_001032"
     CDS             14873..15697
                     /locus_tag="ACG8ZV_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFS4996388.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPEIP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            15862..16761
                     /locus_tag="ACG8ZV_001033"
     CDS             15862..16761
                     /locus_tag="ACG8ZV_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4996389.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(16887..17756)
                     /locus_tag="ACG8ZV_001034"
     CDS             complement(16887..17756)
                     /locus_tag="ACG8ZV_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFS4996390.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            17909..19369
                     /gene="rhaB"
                     /locus_tag="ACG8ZV_001035"
     CDS             17909..19369
                     /gene="rhaB"
                     /locus_tag="ACG8ZV_001035"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008993 - rhamnulokinase activity
                     [Evidence IEA];
                     GO_process: GO:0019301 - rhamnose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HFS4996391.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            19366..20622
                     /gene="rhaA"
                     /locus_tag="ACG8ZV_001036"
     CDS             19366..20622
                     /gene="rhaA"
                     /locus_tag="ACG8ZV_001036"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008740 - L-rhamnose isomerase activity
                     [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0019299 - rhamnose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HFS4996392.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            20636..21481
                     /gene="rhaD"
                     /locus_tag="ACG8ZV_001037"
     CDS             20636..21481
                     /gene="rhaD"
                     /locus_tag="ACG8ZV_001037"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008994 - rhamnulose-1-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019301 - rhamnose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HFS4996393.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            21483..21794
                     /gene="rhaM"
                     /locus_tag="ACG8ZV_001038"
     CDS             21483..21794
                     /gene="rhaM"
                     /locus_tag="ACG8ZV_001038"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0062192 - L-rhamnose mutarotase activity
                     [Evidence IEA];
                     GO_process: GO:0019299 - rhamnose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HFS4996394.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            21876..23027
                     /gene="fucO"
                     /locus_tag="ACG8ZV_001039"
     CDS             21876..23027
                     /gene="fucO"
                     /locus_tag="ACG8ZV_001039"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008912 - lactaldehyde reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HFS4996395.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEASVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            23154..23912
                     /locus_tag="ACG8ZV_001040"
     CDS             23154..23912
                     /locus_tag="ACG8ZV_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HFS4996396.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIKTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            24012..24656
                     /locus_tag="ACG8ZV_001041"
     CDS             24012..24656
                     /locus_tag="ACG8ZV_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HFS4996397.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            24663..25670
                     /locus_tag="ACG8ZV_001042"
     CDS             24663..25670
                     /locus_tag="ACG8ZV_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PfkB family carbohydrate kinase"
                     /protein_id="HFS4996398.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            25686..26528
                     /gene="kduI"
                     /locus_tag="ACG8ZV_001043"
     CDS             25686..26528
                     /gene="kduI"
                     /locus_tag="ACG8ZV_001043"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008697 -
                     4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0045490 - pectin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HFS4996399.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            26548..27351
                     /locus_tag="ACG8ZV_001044"
     CDS             26548..27351
                     /locus_tag="ACG8ZV_001044"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HFS4996400.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(27600..28664)
                     /gene="fni"
                     /locus_tag="ACG8ZV_001045"
     CDS             complement(27600..28664)
                     /gene="fni"
                     /locus_tag="ACG8ZV_001045"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HFS4996401.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(28661..29746)
                     /locus_tag="ACG8ZV_001046"
     CDS             complement(28661..29746)
                     /locus_tag="ACG8ZV_001046"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HFS4996402.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            complement(29759..30736)
                     /gene="mvaD"
                     /locus_tag="ACG8ZV_001047"
     CDS             complement(29759..30736)
                     /gene="mvaD"
                     /locus_tag="ACG8ZV_001047"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HFS4996403.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            complement(30729..31673)
                     /gene="mvk"
                     /locus_tag="ACG8ZV_001048"
     CDS             complement(30729..31673)
                     /gene="mvk"
                     /locus_tag="ACG8ZV_001048"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HFS4996404.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            31989..32648
                     /locus_tag="ACG8ZV_001049"
     CDS             31989..32648
                     /locus_tag="ACG8ZV_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFS4996405.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            32733..33638
                     /locus_tag="ACG8ZV_001050"
     CDS             32733..33638
                     /locus_tag="ACG8ZV_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFS4996406.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(33640..34272)
                     /locus_tag="ACG8ZV_001051"
     CDS             complement(33640..34272)
                     /locus_tag="ACG8ZV_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HFS4996407.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     misc_feature    34423..34548
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            34592..35116
                     /gene="infC"
                     /locus_tag="ACG8ZV_001052"
     CDS             34592..35116
                     /gene="infC"
                     /locus_tag="ACG8ZV_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HFS4996408.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            35188..35388
                     /gene="rpmI"
                     /locus_tag="ACG8ZV_001053"
     CDS             35188..35388
                     /gene="rpmI"
                     /locus_tag="ACG8ZV_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HFS4996409.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            35441..35800
                     /gene="rplT"
                     /locus_tag="ACG8ZV_001054"
     CDS             35441..35800
                     /gene="rplT"
                     /locus_tag="ACG8ZV_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HFS4996410.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            36052..37389
                     /locus_tag="ACG8ZV_001055"
     CDS             36052..37389
                     /locus_tag="ACG8ZV_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HFS4996411.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            37437..39566
                     /locus_tag="ACG8ZV_001056"
     CDS             37437..39566
                     /locus_tag="ACG8ZV_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HFS4996412.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLLENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            39541..40230
                     /locus_tag="ACG8ZV_001057"
     CDS             39541..40230
                     /locus_tag="ACG8ZV_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996413.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(40638..41324)
                     /locus_tag="ACG8ZV_001058"
     CDS             complement(40638..41324)
                     /locus_tag="ACG8ZV_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFS4996414.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QVKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTHLNRFR
                     WLRLTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDY
                     FEDIQDRPIK"
     gene            complement(41460..41654)
                     /locus_tag="ACG8ZV_001059"
     CDS             complement(41460..41654)
                     /locus_tag="ACG8ZV_001059"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996415.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(41704..42144)
                     /locus_tag="ACG8ZV_001060"
     CDS             complement(41704..42144)
                     /locus_tag="ACG8ZV_001060"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HFS4996416.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            complement(42148..42993)
                     /locus_tag="ACG8ZV_001061"
     CDS             complement(42148..42993)
                     /locus_tag="ACG8ZV_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HFS4996417.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            43142..44560
                     /gene="pepV"
                     /locus_tag="ACG8ZV_001062"
     CDS             43142..44560
                     /gene="pepV"
                     /locus_tag="ACG8ZV_001062"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HFS4996418.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(44617..45564)
                     /locus_tag="ACG8ZV_001063"
     CDS             complement(44617..45564)
                     /locus_tag="ACG8ZV_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFS4996419.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(45787..46137)
                     /locus_tag="ACG8ZV_001064"
     CDS             complement(45787..46137)
                     /locus_tag="ACG8ZV_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HFS4996420.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            46337..47416
                     /gene="pepA"
                     /locus_tag="ACG8ZV_001065"
     CDS             46337..47416
                     /gene="pepA"
                     /locus_tag="ACG8ZV_001065"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HFS4996421.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            47560..47880
                     /locus_tag="ACG8ZV_001066"
     CDS             47560..47880
                     /locus_tag="ACG8ZV_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HFS4996422.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            47902..48366
                     /locus_tag="ACG8ZV_001067"
     CDS             47902..48366
                     /locus_tag="ACG8ZV_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFS4996423.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            48571..49176
                     /gene="ytpR"
                     /locus_tag="ACG8ZV_001068"
     CDS             48571..49176
                     /gene="ytpR"
                     /locus_tag="ACG8ZV_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtpR family tRNA-binding protein"
                     /protein_id="HFS4996424.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(49215..50504)
                     /locus_tag="ACG8ZV_001069"
     CDS             complement(49215..50504)
                     /locus_tag="ACG8ZV_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HFS4996425.1"
                     /translation="MDRKNVTPKMKKNKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            50932..51411
                     /gene="rlmH"
                     /locus_tag="ACG8ZV_001070"
     CDS             50932..51411
                     /gene="rlmH"
                     /locus_tag="ACG8ZV_001070"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HFS4996426.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYGLAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            51764..52078
                     /locus_tag="ACG8ZV_001071"
     CDS             51764..52078
                     /locus_tag="ACG8ZV_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFS4996427.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            52094..52480
                     /locus_tag="ACG8ZV_001072"
     CDS             52094..52480
                     /locus_tag="ACG8ZV_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFS4996428.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            52509..53894
                     /locus_tag="ACG8ZV_001073"
     CDS             52509..53894
                     /locus_tag="ACG8ZV_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HFS4996429.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            53897..54050
                     /locus_tag="ACG8ZV_001074"
                     /pseudo
     CDS             53897..54050
                     /locus_tag="ACG8ZV_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            54073..55278
                     /gene="mobT"
                     /locus_tag="ACG8ZV_001075"
     CDS             54073..55278
                     /gene="mobT"
                     /locus_tag="ACG8ZV_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobT family relaxase"
                     /protein_id="HFS4996430.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
BASE COUNT        17556 a        10114 c        11872 g        15798 t
ORIGIN      
        1 cgcttcatcc atgtcatggg ttacaaatac gatcgttttt cccaaacgct cttgtaaatc
       61 tttgacaagg tcttgcaagg aatcacgagt gattggatca agcgcaccga atggctcgtc
      121 catcaagatg atatcttgat tcgctgcaag ggcacgaacg actccaatac gctgctgctg
      181 accaccagat aattcatgtg ggtagcgatc taacatctca cggggcaatt ccacaagatc
      241 aatcattttt tcagctgttt tattccgttc ttcttgactg actttcaaca atttttggac
      301 aagagtgata ttttcacgga tcgtcatgtg aggcatcaat ccaatacttt ggataacata
      361 gccgatctga cgtcgcaatt ccactggatc aatttcttgg atggattttc catcaatcaa
      421 aattttccct tgtgttggat cagtcattcg gttgatcatc cgcatcgtcg tcgtttttcc
      481 gcttccgctc gtaccgataa aacaaatgaa ctcacccttt tcaaatgaaa gattgacgtc
      541 ctctacagcg acttttccac ctttataaat ttttgacaca ttttgaaatt caatcatggt
      601 gccacctctt tttctatttt caatgaagaa ctatctatta ctagtatgcc taaaacaatg
      661 aaaaaataca aatagggtag tttttttatt taggaaaaca aaaaatagaa gtgaaaaagt
      721 gctgattttg ccaacagaac gaaaaacatg atagaatgat gaagcacatg atagaaagtg
      781 agtgacgata tgttaacaac agaagatttt gattttgact tgccggaaga attaatcgca
      841 caaacaccat taaaagaccg cgatcattct cgtttacttg ttttggatcg gaaaactgga
      901 gagatggaag ataaacattt ccatgaaatc attgaagagt tacagcctgg tgatgcgcta
      961 gttatgaata atacacgagt tctgcctgct cgtttatatg gagaaaaacc agatactggt
     1021 gcgcatttag aagtccttct tctaacgaat acacaaggag atacgtggga gacattgatc
     1081 aaacctgcga aacgtgccaa agttgggaca agaatctctt ttggtgatgg cagattgcaa
     1141 gcagtagtga aagaagaatt ggaacacggc ggacggatca ttgactttga gtatgaagga
     1201 atttttctag agattcttga atcattggga gaaatgccat tgcctccata tatcaaagaa
     1261 cgtctggaag acccagatcg ctatcaaact gtctatgcga aagaaaatgg ttctgctgca
     1321 gcgccaacag ctggattgca ttttacgaaa gaattacttg atgagatcga agcaaagggt
     1381 gttgaattag tctatctgac actacatgta gggttaggta cattccgacc tgtcagcgta
     1441 gataaaattg aagaacacca tatgcatagt gaattctacc gtttgacgga agaagcggct
     1501 gagcgattga accaagtacg taaaaatggc gggaaaatcg tggctgtcgg aacaacttca
     1561 attcgaacat tagaaacgat tggaacgaaa tttaatggag aaatcaaagc agacagcgga
     1621 tggactgata ttttcattac gcctggctat gaattcaaag tggtagaagc tttctcaact
     1681 aatttccatt tgccaaaatc gactttagtc atgttagtta gtgcctttgc aggaagagaa
     1741 ttgactttat ctgcttacca gcatgcgatt gaagagcgct atcgtttctt tagttttgga
     1801 gatgcgatgt tcgtgaaata aggttatgaa aagccgctag ttttgaataa caaaaaagct
     1861 ttacaaagat tttatgacaa agaaaaagcc gagctctcga taagctcggc tttcttgtac
     1921 ctcggaagga ttcaaataaa cagaaatgat tgtaactttc catcatacat gcaaagcacg
     1981 gtgttgaatt tcttcatgtt aaacaaaaat tttgttttcg ttacatcttc aacatttgaa
     2041 acatctcttg ttcctattca attttcagac gtttacgtta ttcaattgtt acgtatcgca
     2101 ttacttcttg tttcggatac ttcgtgatcc aaacatccat acgcattcac tatttatagg
     2161 tttgtactct acacgcatgt ctgggtgaaa cctgtacttc taacaacttt gtttgcttac
     2221 actgttctat cgagaaattc ttctgtctat ttgatggtat cctccttcct tacatctata
     2281 taatagcatc ctttggtagc gtttgcaaat ataagcactt taaattttac gctttcttaa
     2341 caaataatcg ataagccctt tatttgaagt aaataaaaaa aggatgttat agtaaaataa
     2401 gtaccttttt ttgtacgaag attttaaagg aggaatagga tggaagaata caagcagaca
     2461 atagaagaag taaagaaggt aacagaagca gatccagata ctgggttgtc ttcacaagaa
     2521 gtggatgaac ggcgaaaaaa gcagggattg aataaattcg atgaggcgcc gaaagaatcg
     2581 atgatcaaaa aattctttcg aagcttgtcc gattttacaa cgatcatcct tcttgtagca
     2641 gcggtgattt ccttttatac cgcatttgct acagaacatg gggatttatt tgaaggactg
     2701 ctgatcatcg ctatcgttgt gatcaactcg gtattggcga ttgtccaaga aggaaacgca
     2761 gaaaaagcac tggaatcctt gcaagatatg aataaacaaa cggcaactgt catacgagac
     2821 ggcaaagtga ccactgttga gtcagagcaa ctggtagtgg gtgatattct tgttttagag
     2881 tccggtgatg ctatttctgc cgatgcccgt ttgatcgaag catcacaatt acgtgtagaa
     2941 gaatcggcgt tgactggaga aagtgaagca gttgaaaaag atgcagcatt tattgctgaa
     3001 gaagatgagt cattaggtga ccaacttaat atggtattta aaggatgtac ggttgctgca
     3061 ggtcgtggga aagcgatcgt cactgccatt ggcatggcta cagaaatggg taagatcgcg
     3121 gatcttttga acgaaaatac tatgcaaaaa acacctttac aggtccgatt gaatcagcta
     3181 ggcaaacgaa tcagtatgat cgctttagcg gctgcggctt tagtatttgt gattggtgaa
     3241 ctgcaaggag aaccactcct tgagatgttc atgacttcga tttccttggc tgttgcagct
     3301 gtaccggaaa ccttgactgt tattgttacg ttgacacttg catacggtgt gcagaagatg
     3361 gcgaggaaac atgcgatcat ccgacagttg ccagcagttg aaacgctagg aaccgctaat
     3421 gttatctgct cagacaaaac aggaacgctg acacaaaatg aaatgcgcgt ccgccgggta
     3481 tggagcaaag aagatgaagt aacgaatatc gaagattcaa tgacgaacag cgcgatggaa
     3541 atattgaaaa tggctgcact atgtacagat gtgacggtcg agcaagaaga tgacgacctt
     3601 gttatcaaag gtaatccaac agaagtagcc atcgtaaggg ctgttgaaga gaattatcat
     3661 acaaaggcag aattagaaga aaaatatcca cgagtaaacg agcttccttt tgattctgaa
     3721 cgaaaaatga tgacaacagt tcaccaaatg ggcgaaaaat acatctcaat caccaaagga
     3781 gcattcgatg ttcttgctcc gcgctttagt tcaggcgatg tagaacaagc ggcgatcgtt
     3841 aatgatcgct ttggtaaacg ggcactgaga gtgattgctg ttggttatgc tacttatgac
     3901 gaagaaccgc aagatatttc ttctgaagca ctggaaaaag acttacgttt gattggtctg
     3961 atcggaatga tcgatccacc acgtccagaa agtaaaggag caatcaagcg agcgaaaaag
     4021 gctggcatca aaacagtcat gatcactgga gatcatgtgg tgactgccag tgccatagcg
     4081 aaagaattag gtatcttgaa tgatccgtca gaagcacttt caggatcaga actgcatcaa
     4141 ttatcagacg aagaattaga tgcgcgtgtc aaagctctct ctgtctatgc tcgggtaacg
     4201 ccagaagaca agatccggat cgtcaaatct tggcaacgta cgggtgcagt cgtagcgatg
     4261 actggggatg gtgtgaatga tgcaccagcg ttgaaagcaa gtaacgttgg gtgtgccatg
     4321 gggatcacag gaacagatgt ggcgcaaagt gccgcagata tgattttgac ggatgacaac
     4381 tttgcgacga tcgtagacgc tgtcagtcaa ggacgttcgg tttatcagaa tattcgtaaa
     4441 gctatcaact ttttgctaag ctgtaatatt tcggagatct ttattgtttt gattgcgatg
     4501 ctgttaggat ggggagcacc atttacagct gtgcaactac tgtttgtcaa tgtagttgct
     4561 gatggacttc caggatttgc tttaggaaga gagccagcgg aacacggcat catggatcag
     4621 ccacccattc cgaaaaatga agggatcttt gctcgaggtt tattgcaaaa aattgccata
     4681 aatgcagggg tcttcaccat cgtaaccttg tttggttatt atttaggtag ttatgtcgat
     4741 actatcagcc catgggtaga cgcaagtcag catgtcggtc aaactgttgc attcttgatc
     4801 ttagcttatt catcgattct gcatgtgttc aatgtacgca gcagccaatc gatcttcaaa
     4861 gtcaatttag cgaccaataa agctttggta gaaatggcgt tactggcatt agctattaca
     4921 acggctgttg ctttgctgcc atttacgcaa gaactattcg gcctagtaca catcagtttg
     4981 aatcactggt tcttggtagg gattttatct atcgtaccaa tcgcggtgaa tgaactgatc
     5041 aagttccatc gattaccgga agcagaagaa gaggaatgat taactgtttc taagttgatt
     5101 ttctttttac tggaactata caaaaaggag gtgtgacatg aatgttgtca cacctccttt
     5161 ttgctaatgg gctgaatgtt tcttttactg cctctcgata aacggtgttc tcctgccacc
     5221 ccctcggtca caagtcacac tctcttttaa atatcttttg gcaattgttc ataaaatgct
     5281 gcttttgttg cagaaatgta tgggctgagc catagataac caataccagc agttgctaat
     5341 gctaagatat gccagccgat aaatgaaaga tctaaccaga aaagttgtcc tttataacca
     5401 tccatcaatt ttcgacttgc agtgatcgta tccagtactt taggtgtttg tcctgtttct
     5461 tggacgatat cgtagtaaat aaaatagctt tgagaataag aatagctttt aatgattcca
     5521 ggaataacta atagcaaacc ccataatgtt gtaaagatcg agatcagcac agctaagctg
     5581 atcactccgc cgataaacaa acctttgaat ccacgaaatg catctttgaa tggttcgatc
     5641 tgatcttttt gtccacgtaa aatatcaaga taagtccaag aaataccgct catgaacaaa
     5701 gcgctaatga tgctggaaat aattccgcca ccgcctcctg aactaccgcc tcctgaagtt
     5761 gtcgcttctg agacgctcgc tgatccatca tatatggtgg tggcaaacaa gataatagga
     5821 atcataataa gaagaatagt agcaatacca atcaatgtag ggattagatt tagtaaaaca
     5881 gcttgtcccc aacgtccttt tagactctct tttgcttggc gttttaattc tgcagaagat
     5941 tgcatgattt ttccctcctt ttctttaata acaccaatat accatgtatc aaaaaatatt
     6001 tctgtcataa tgtttttctt ttttttgtta ttcataaaaa aaggataaaa aaagaatatt
     6061 aaataaagta gaaggaagcc gagggaactt gcaaaaagca cttgaaacga ttatgatggt
     6121 gggagttgtc aagatatttt atatagaaag tagggaaatg aatgacgcaa cctgccattc
     6181 gctatcgttt aatcaagaaa gaaaaacata ctggcgcgcg tttaggggaa ttgatcacgc
     6241 cacacggaac tttccccaca ccaatgttca tgccagtagg aacattagct acagtaaaaa
     6301 caatgtcccc agaagagttg aaagaaatgg gtgctggcgt tattttaagt aatacatatc
     6361 atttatggct acgccctggt gaagacttag tagaagaagc tggcggactg cataaattta
     6421 tgaactggga tcaaccgatt ttaacagatt caggcggctt tcaagttttt tcattaagtg
     6481 atatgcggaa tatcgaagaa gaaggcgtgc atttcaaaaa tcacttgaac ggttcgcgta
     6541 tgtttttatc accagaaaaa gcaatcaaca tccaaaataa attgggctct gatatcatga
     6601 tgagttttga cgaatgtcca ccattcgatg aaagttacga ctacgtgaaa aaatcagtag
     6661 aacgtacgtc tcgatgggca gaacgaggat tgaaagctca tgctaatcca gaccgtcaag
     6721 gattatttgg aatcatccaa ggagcagggt ttgaagatct tcgtcgtcaa agcgcgaaag
     6781 atctagtcgg gatggatttc cctggttact caatcggcgg gttatctgtc ggggaaccta
     6841 aatcagaaat gaatcgtgta ttagaattca ctacaccgtt gatccccgaa aacaaaccac
     6901 gttacttgat gggtgtcggt gctgctgatt cgttgatcga tggtgttatc cgtggagtag
     6961 acatgtttga ctgtgtcttg cctactcgaa tcgctcgaaa tggcacatgt atgacttctc
     7021 aaggccgtct agtagtgaaa aatgcgaaat atgcccatga tttccgtcca attgatgaga
     7081 aatgtgattg ttatacatgt aaaaactata cacgtgccta tatccgccat ttgatcaaat
     7141 gtgatgaaac atttgggatt cgtttgactt cttaccacaa tttatacttc ttgttgaatc
     7201 taatgaaaca agtacgtcaa gcaatcatgg atgataattt gcttgaattt agagaagcct
     7261 tttttgaaga atacgggttc aataaagaaa acgcaaaaag cttctaaagg aaaatctttt
     7321 aaaaattaag taaaaaacta gtgttatcag catttttctg ctaaagtgtt ttttgtagat
     7381 acagaattag tgaggtgaaa aaaatgggaa cattaccaat gcttgtgatg tttatcgcgc
     7441 tattagcaat gtggtttttt atgtcacgtt cgcaaaagaa acaacagcaa gaacgtcaaa
     7501 acttgttaga tagcatgaaa ccaggtgatt cagtcgtaac gatcggcgga ttacatggag
     7561 ttgtttcaga aatcgacaat gacaaacgga cagttgtttt agactgcgaa gggatcttcc
     7621 ttgagtacga tcgtgcagca atcaaaacgg tcaaaccagg gactgtcgta acaaatgatg
     7681 caacgactac tgttgaaaca acagaagaac cagctgagac agttgaagta aaaactgaaa
     7741 caacagaaac gctggaagag acagaagaga aggaagaaaa ataagtatca aagcttattt
     7801 aaagacgagg tagggcagaa agatgtccta cctcattttt tattcaaaaa agaaagagat
     7861 aagagcatgg gatatattgc tcaatattga ataatcgggt gtgtcatata aataataata
     7921 aataacttta tatatttttc tatacaaaca cctgtaaata aagcaatttt atatttaaaa
     7981 ataactgtga aaaaaatcac aaaaaagtgt ttacatagaa aaataaatat tgtatgatat
     8041 acatgtgaat tatttaacaa ataaccatga cccattagga ggataatgat ggctaaagta
     8101 atagaaaaag aaaaaacgaa gacaattgac gtacaagcaa tgattgatga tttggcagaa
     8161 aaagcaaatg cagcattgaa agaaatggaa agctttgatc aagaaaaagt agaccatatc
     8221 gtgcatgaaa tggcaatggc agctttggat caacatatgc cattagcgaa gatggctgta
     8281 gaggaaacag gccgcggtgt ttacgaagat aaagcaatca aaaatatgta tgcgtccgaa
     8341 tatatttggc ataatatcaa acatgataaa acagttggtg tgatcaatga agatgtccaa
     8401 aaagggttga ttgaaattgc tgaaccagtc ggtgtggttt gcggagtaac tccaacaacg
     8461 aatccgactt ccacaacgat tttcaaatca atgatcgcgt tgaaaacaag aaatccaatc
     8521 gtttttgctt tccatccaag tgcccaaaaa tcttctgcag aagcagcacg agtggtacgt
     8581 gatgctgcta tcgctgccgg agctcctgaa aattgtatcc aatggatcga acatccttcg
     8641 atcgaagcga cttctatgct aatgaaccat ccaggtatcg cgatcgtctt agcgacaggt
     8701 ggagctggaa tggtcaagtc tgcttactct acaggaaaac cagctttagg tgtaggtcca
     8761 ggtaacgtac cagcttatat tgaaaaaaca gcaaaaatta aacgtgcagt gaacgatttg
     8821 atcgtttcga aaacatttga taatggaatg atttgtgctt ctgaacaagc tgtgatcgtg
     8881 gataaagaaa tctatgcagc agtaaaagca gaattccaag cacaccaagt ttatatcgta
     8941 aaaccagatg aattgcaaaa attagaagat gcagtgatga acgaaggaaa atatgcggtc
     9001 aatccatcaa tcgttggaca ttctgcgatg gaaatcgcaa aattggcagg aatcagtgta
     9061 ccaaaaggaa cgaaaatgct gattgctgaa ttggaaggcg taggcccaga ttatccgcta
     9121 tcaagagaaa aactttctcc agttcttgcc atgatcaaag ctaacaacac ggaccatgcg
     9181 tttgatttgt gtgaaggtat gttgaatctt ggaggattag gacatacagc agttatccat
     9241 tcagaaaacg aagagttgca tgtcaaattc ggtcttcgaa tgaaagcttg tcgtatttta
     9301 gtgaatacac catctgcaga aggcggcatc ggtgatatct ataacgaaat gattccgtca
     9361 ttgactttgg gatgcggttc ttatggtaag aactctgttt ctcgtaacgt ctctgctgta
     9421 aacttaatca atgtcaaaac tgtagcgaaa cggagaaata acatgcaatg gttcaaatta
     9481 ccgccaaaaa tcttctttga aaagaactct ctattgtact tagagaaaat ggaaaacgtt
     9541 gaacgtgtca tgatcgtttg tgaccctggt atggtccaat tcggttactg cgatacagtt
     9601 cgtgaagtat tggcacgacg taaaaatgat gtgaagatcg aagtcttctc agatgttgaa
     9661 ccgaacccat cgacaaatac cgtatacgca ggaacgaaac tgatggcaga cttcaagcca
     9721 gatacagtaa tcgctcttgg aggcggttct gcaatggacg cagctaaggg aatgtggatg
     9781 ttctatgaac acccagacac atctttcttt ggtgcaaaac aaaaattctt ggatatccgt
     9841 aaacggacat ataagatcga caaaccagaa aaaacacaat tcgtatgtat cccgacaaca
     9901 tcagggactg gttctgaagt aacgccattt gcggtcatca ctgacagtga aacacatgtg
     9961 aaatatccgt tagcagatta tgcattgacg ccagatgtcg caatcgtcga tcctcaattc
    10021 gtcatgtcag ttccagcatc tgtcacagca gataccggga tggatgtgtt aacacatgca
    10081 atcgaatcct atgtttcagt catggcttca gattatacac gtggattgag cctacaagca
    10141 atcaagttag tctttgacta tttagaaaaa tcagtaaaaa cacctgatat ggaatcacgt
    10201 gaaaaaatgc acaacgcttc tacaatggct ggtatggcgt ttgctaacgc attcctaggt
    10261 atttgtcact cagtcgcaca taaaatcggc ggggaatacg ggatccctca tggacggaca
    10321 aatgcgattc ttttaccgca tattatccgc tataatgcaa aagatccaca aaaacatgcg
    10381 atgttcccta aatatgacta tttccgtgca gatacagatt acgcagatat cgcaaaattc
    10441 ttaggtctga aaggcgaaac aacagaggaa ttagtcgaag ctttagcaac ggctgtttat
    10501 gaattaggaa aatctgtcgg catcaacatg agtctaaaag ctcaaggagt cacacaagaa
    10561 acactagata caaccgtaga ccgtatggct gaattagctt acgaagacca atgtacgaca
    10621 gctaatccga aagaaccatt gatctctgaa ttgaaacaga tcatcattga tgcttacaac
    10681 ggataagcaa aagaaagcgt agaaaaaaga taagaaaata gatgaaaaag aacttggaaa
    10741 acgttgtttc tccaagttct ttttttaatt tccaagtaac tgaaagttac ttttgttatt
    10801 taacatttag gtcaatttta gacagttttt gttcaaaaag cgatatttat agtggacggt
    10861 attactgcta tattaaggat ataaaatgaa agcgtttaaa aaggtggcgt aaagatgatt
    10921 attaaagaag agatttttgt acctaaagaa ttagtgaaag aaaaaattga cctgctcgtt
    10981 gaaaacctga caacgatcaa agacgataat ggtgaatttt tgttggactt tgatggactg
    11041 aaagtagatg acaaaagctg gacagtgtgg aattggccac aaggtgtcgg tctatatggt
    11101 atttataaaa attaccagat gacaaaaaat cctcgcgctt atcaagtggt caatgaatgg
    11161 tttgaggatc gtatggaaga aggcgctccg cccaaaaacg tcaatacaat ggcaccgcta
    11221 ttgactatgg cttacttgta tgaagacacg aaagattcac gctatttgcc ttatttagaa
    11281 caatgggcag aatgggtcat gaatgacatg cctcggacaa atgaagacgg gttacagcat
    11341 gccacatatg gaccggaaaa taagaatcag ttgtgggacg atacattgat gatgacagtg
    11401 cttcctttgg caaaaatcgg gaaactgttg aatcgcccag aatatttaga agaagctcgt
    11461 taccagttta tgatccatat caaatacttg atggataaac gaacaggatt gtggtatcac
    11521 ggctggacgt ttgaaggaaa tcataactat gccgaagcat tttgggctcg tggaaactgc
    11581 tggttgacga ttgctattcc agagatcatt gaaatcttag aattatcgaa agaagatgca
    11641 ttgcgcaaat tattgatcga aacacttgaa gcacaagtgc gtgcattaaa aacttatcag
    11701 tctgaaagcg gtttatggca tacgttgttg gatgatcctt cttcttacgt agaatcttct
    11761 gcaactgcag gatttgctta cggtattttg aaagcggtcc ataaacgtta tttaccacaa
    11821 gaatataaag aagtcgctta tcgtgctatc caaggattgc ttgaacaaat cgatgaaaaa
    11881 ggagaagttc aaaacgtttc aatcgggaca ggaatggggg acagtttaga tttttatcgg
    11941 aatatcggaa tcacagcaat gccttatgga cagtcgttaa cggtgctttg tttgacagaa
    12001 ttgctcgtct cttattgtta aaagaaagga aacccatatg aaaaaaacat cactgctgtt
    12061 tgcagcaagt tcgcttagcc taggtctgct aggtctaagc ggctgcggaa ataattctag
    12121 tgtggcaact gtcgcagatg cagatgtaaa tgagatagtt accttgcgct ttgcttatgc
    12181 aagcaacagc cagccagtaa ttgatgcaat gaatgaattt gggcgtttag taaaagaaaa
    12241 aacagatggt tccgtacaga tccagtattt cccagatgga caactgggtg gagaacgtga
    12301 actgatcgaa ttgacacagt caggagcagt agatttcaca aaagtaagtg cctcagcgtt
    12361 ggaaagtttc tctaaagatt attcgatttt ttcagttcct tatctattca atgatgaaga
    12421 acatttcttt aaggtgatgg ataatgaaga aataatggag ccaatctacc aatcgaccaa
    12481 aaatttagga tttaccggat tgacctatta tgattctggt cagcgcagct tttatatggt
    12541 agacggtccg atccatacgc cggaagattt gaagggaaag aagatccgtg tgatgcaaag
    12601 cgaaaccgct atcaaaatgg tagagctttt aggcggttcg cccgtaccta tgggaagtga
    12661 tgaagtgtac acgtctcttc aatccaattt gatcaacgga tcagaaaaca atgaatttgt
    12721 cttgtataca gctggacatg gtggtgtggc taaatactat tcctatgatg agcatacacg
    12781 tgtgccagat atcatcatca tgaatgatgc catcaaagaa cagctaactg atgagcagga
    12841 aaaagccatt gaagaagcag cgaaagaatc aacggttttt gaaattgaag cttttgcaaa
    12901 agcaattgaa gaagaaaaag ctttagcaca agaagaacat ggagtccaat tcaatgatgt
    12961 agataataca ccgtttcgag aggcagttgc cccacttcat gatatattca aaaacgatcc
    13021 tacctacaaa gacctttatc aaaagatcca agagcaagga gcgtagctgt gatgaaaatg
    13081 attttaaaca aggtattaga gatcctggga gctgttttgc ttgttgggat ggtcgctgtt
    13141 gttttatggc aagtattttc cagaacggtt ttaggaaatc caaatacggt cacggaagag
    13201 cttgttcgat tcggtcttgt ctggtttgcc atgttgtctt ccgcgtatgt tgtgggacaa
    13261 aaagcacatt tagccgtaac ggttttaagt gaaaaattaa ctggcaaaaa aagtaaaatt
    13321 ttagaagttg ttgttcaaag tttatttctg gtatttgctg cgatgatcat ggtgtatggc
    13381 ggatggaatg ctgtcacatt gacaatgggg cagatctcgc cttctttaag tattcctatg
    13441 ggatatgttt atctgtcagt acctgtatcg ggggtactca tcattatcta tagcctgatc
    13501 aatctaatcg atacattaag caacaagcca gcaattcaag aaaaaatata aaaatggagg
    13561 aataaaatgg caatagaagc cggattagtg ttattttttg tatttgttgt gttgcttgta
    13621 ttagggatgc cgattgctat aagtattgca ttctcatcga tgatgacttt attgttagtt
    13681 ataccgtttg atgtttctgc ttttagttca gctcaaaaaa tggtgggaag tatcaatagt
    13741 ttttcgctga tcgctattcc gtttttcgtt ctctcgggca ttatcatgaa taatggaggg
    13801 atagctaaga aactagtgga ttttgcgatg ttgttcgtcg ggcgcgtgcc gggggctttg
    13861 gctcatacga atgtgttagg gaatgcttta tttggttcca tctctagctc ggccattgcc
    13921 gcttctaccg cgattggcgg agtgttgatc cctcagcaag tggaagaagg atatgaccgg
    13981 aagtttgcga cagcggtcaa tatcgcgtca gctccgacag gtatggtcat tcctccaagt
    14041 actgctttta tcatgtattc acttgttgct ggtggtgctt cgatctctgc tttgtttatg
    14101 ggaggttatc tcgtaggcgc tttgtgggcg ctaggaatca tgctagtagc attcatcgtt
    14161 gctaaaaaga ataaataccc tgttgtcgaa aaaggacaga tggctcatgc tggaaaaata
    14221 ataaaagagg cgattcctag ccttctattg attgtcatca ttatcggtgg tatcttgacg
    14281 gggatattta cagcagtaga agcttcagcg atagctgtca tttactccct gttgattgct
    14341 atgttttact ataaaacggt aaaactaaaa gatataccta atatgttgtt tcaatcagta
    14401 gcaatgtcag ggacgatcat gttcttattg gctacttctt ccatgatgtc tttcgccatg
    14461 gcgtttaccg gtattcctca ggcaattagt tcgttgatta tgggcgtaac ggataataaa
    14521 tttattattc tgttattagt caatcttgtg ttattactgg tgggtatgtt tatggatgtg
    14581 gcgcctgcta tcttgatttt tacaccaata tttttaccaa tcgtcacaag tgtaggggtt
    14641 gatcctgtac attacgggtt gttttcaatc atgaatctgt gtgtaggctc catcacgccg
    14701 ccagtaggta caggactata tgtcggtgca agtgtaggag gcgtaaaagc agaggcaatg
    14761 ctgaaaccgc ttcttccttt ttatggggtt atcttagtcg tcttgttttt gattacttac
    14821 ttcccgcaaa tcgtcatgtg gctacccaat atgctgagtt aggagaatag ttatgttgaa
    14881 cattacaatt agaggacatg atctttccga agtccaaacg atagaagatc ttgcagaaaa
    14941 aacaaaagaa caagggattc atacactgca gctcgcctta ggtctttcgt ttcctgaaat
    15001 accttctggc gcaaatgaga tcaattctgg gatgggaaat tatgtcaaac gagttttaga
    15061 aaagcaagaa gtgaccgtag gaattttaag ttgctatatc aatatgattc atccagattt
    15121 aacgatacga caagagttgc tgacaaagtt cgagcagtat cttcgctatg cttcttcctt
    15181 tggtgcgtcg atggttgctt cggaaactgg atgtgttttg ccggaaatcc aatatacgga
    15241 agaaaatttc acagatgaag catttgctga agctgtgtcc gttatccgtc gcttggtaaa
    15301 agctggagaa aaataccaaa tgatggtggg gatagaacca ggtttgaatc atccggtgta
    15361 ttctttagca agggtagagc agctgatcca agcagtagat tcggactatc taggaatcat
    15421 tttagatccg accaatttga tcacaagtag tgattatcaa gaacaagtcc aattggtaga
    15481 agaagctttt gaacgttttg gtgaaaagat atgtgcggtt catttgaaag attttcgtgt
    15541 cgaacaggaa aaaatcgtgc cggtaaattt gggagacggt gtgatcgagt acacaaaaat
    15601 caaagaaatc atcatgaaga atcgtccgta cctgtatgtg gttcttgaag aaacaaaaga
    15661 tgatgggatt cgttatggaa gaagtcttct tgaataatgt aaagaagacg ttggttaact
    15721 aatatttaga atggaggggg cggggctaga agatgccacg tctcttcttt tttataagag
    15781 tatataaaag cagctctttt tgattacaaa aaacgtggta taataaaatt gtgcataagt
    15841 gaacaaaagg aggtgcggca catgctccaa aagaaaatca gcggtgaaca agtcaatacg
    15901 atggtttctg atcagtatga aatctatcat gtcaaagatg tcgtcagcca aaataaaacg
    15961 atctatcatc atcatgattt ctatgagatc catgctacat taaagggaga agcgactttt
    16021 tatttgaacg gacgacaatt tacgatcaaa gcaggaagtg tgctgctcat ccattccaat
    16081 gatttgcatc gtatcgtccg ccaatcttca gatgtattcg agcgtgtcta tatctttgtc
    16141 accccttctt ttctagaaag tcgttccacg ccatggtcta atctatcggc ttgttttcaa
    16201 ccaatgggag agaagaggag tcgtgtattg caaatagaac aggaagtatt gaagcaaaaa
    16261 ttatcattta tcgaccatcc tcctgataaa aaaatttacg gtgaagacat aaaatatgaa
    16321 caagctctgg tagaatactt gatttttctc aatcaagttg tacaaaaaga agagagtgcg
    16381 caagaacaga atgctgtagt tcctaatgag cgtgtggaac aaatgttaca atatatctca
    16441 aaaaatttat ctcatccgct ttctttagag gaaatggaaa agcagttttt tgtcagcaaa
    16501 taccatatca cacgagaatt taaaaagtac actggattta cgtttcatca gtatgtaatg
    16561 aagaaaaagc tgatctatgc caagcacttg ttgcgagaat accgcagctc tagtgctgta
    16621 tatagtaaaa gtggtttttc ttcttatccg cattttctga aagcattcaa gagagagttc
    16681 ggcataacgc ctaaagaatt tttgaaacgt gatacacaga aacagttggt tcattatgaa
    16741 cattttgaag atgaacaatg agaatgatca ctaaaaaata accgcagtag ctgctgttgt
    16801 ttacatagaa gcagaaactg cggttatttt atttttatct atatatttca aaatattttg
    16861 aaaaaatgac gtacatatta tatgaatcag ctgaatttac gaaagtctct cggcgatagt
    16921 cctgtttttg ctttgaacag gcggctaaag taagcaaaat tctcaatccc tatttcttcg
    16981 gaaatcattc gaaccgtaaa ttctgtatac cgaagaaggt ctttagcgta agaaagtttt
    17041 ttgctgatca aataatcgat tggtggagaa ccgataaatt tggaaaaatc tttgctcagc
    17101 tgatatttat tcaataagaa ttgttgttct aattgatcaa gtgtaatcgt ttctttgaaa
    17161 tgttcgtcta agtattgctt cagtttgtaa acgtaggcgg gaatatcctc ttcttcgaaa
    17221 tctagctgat acttttgcaa aatcagttca ttcagcaact cgtggatagc tacagaggac
    17281 tggaaatcgg tacgggcatt cgtgccttgt tgcatgtgga tcaattctgt gatcaaatgg
    17341 tggatcttgt tttctgatgg atctcctgtt gaatggaagg tgttatggcc gtcttttgtg
    17401 aactcctgat aaaatgattg gacgttctga ccattcaaat ggatccaatc catttcccat
    17461 ggttcttcgc tgatcgtttg ataacgctga tattcttggc agtcaataaa aaataagtct
    17521 ccagctttta gctgttgctg attatcatta tatgtaagcg aacctttgcc agacaaagta
    17581 aactttatca agtaagaagg taaatgtgct cgttcagtat agtaagggat tggtgctttg
    17641 aagtaaccga tttcttggat ataaaaaaat aaattcctgc ttctttgtgt aggcgtcaag
    17701 atcactcttt ttgagtcttc cgaccatgag tggttggctt tttcccagta atccatgtaa
    17761 acactcccaa cttgtcaaga taatgcaatt atataccaaa atagtgtgaa gcaaaatata
    17821 agattctgta ttatgatagc attgtcaata aatgataacg ctttattaat aaagtgctaa
    17881 tcaacaataa agtaaaagag gtggagaaat gaatccaaca tttgttgcca tcgatatcgg
    17941 tgcatcaagc ggacgactaa tgaaaagtac gagggatgca aaaggttctt tgatcttgga
    18001 agaagtacac cggttcaaaa acggctttcg gaacaaagac ggtcacgatc gctggaagat
    18061 cgattatctt atcaaagaga ttttgattgg atttgaaaaa ttaaagcaga cagggattga
    18121 tcgccttttt gcggggatcg atacatgggc agtcgattac tgtctgattg atgaacaagg
    18181 ggatcggata aatgatccga ttgcttatcg ggacaagcgt accaatggag cagtagaaca
    18241 gttttctgaa atctattctc tagataagtt gtatgagcag acagggattc agatccagcc
    18301 tttcaatacc ttgttccaat tgtttgctga agaaaaagaa aatttggcaa aagcacataa
    18361 attgttactg atacctgatt atttagggta tgtctttact ggtaacatgg tgacggagaa
    18421 aactaatgca tctactatgc agctgctgaa tgcagggaca aaagaatggg aaatagaact
    18481 tcttgaaaaa atcggtgtct cgaaggaatt atttccacca ttgacagagc cgggaacgat
    18541 actaggagat ctgcaaaaag aacaattttc aaaatatgat ttgccagatg tgacctttat
    18601 cacagtagca agtcatgata cggcgtcagc tgtattagga acgccaggtc aaggagaacg
    18661 ttggggttat atcagcagtg ggacatggtc gcttttaggg attgaaacaa agatcgccaa
    18721 tgtttctcgc aatgcttttt ctgaaaatta tacgaatgaa tggggtgccc ataacacggt
    18781 gcgttttttg aaaaacatca tggggatgtg gttgatccag gaagttgccc gaatgcaaga
    18841 gtacgagtac agttatgcgg aattggcaga gcttgctgca aaagaaaaac cgctgcagca
    18901 agtgatggaa atcaatgacc ctcgattttt gaatccccca aatatgatag aagagattca
    18961 gcaatactgt tttgaaacag agcagccagt ccctgtctca tcgggagcta tcgctcgttg
    19021 tgtgtatgat aatcttgctc tttgttacgc acaagagctg atcaaagtag aacacttaac
    19081 tggaacgaaa ttggaaaagc tgcacatcgt agggggcgga tcgaataatc gtctactgaa
    19141 tcaattgaca gcagattatg ccggaatcat tgtagaagca ggacctagtg aagccacagc
    19201 aatcgggaat gttgccatgc aaatgctcag tacaggtcag ttttcgaata tagaacaagc
    19261 aagaaatgta atcaaacagt cgtttccatg tgaaactttt tacccagatg aaaataagca
    19321 aaacacgatg gaatggtacg tgaataaaat caaaggagta atcgtatgaa cacgattgaa
    19381 agaaattacg aacaagcaaa agaaaaatat gcaactatcg gtgtagatac agatgctgta
    19441 ctagaaaaga tacaggacat caaaatttct atgcattgct ggcaaggaga tgatgtcaaa
    19501 ggtttcttga caccggatgg cgaattgacc ggtggaatca tggcgacagg gaattttcca
    19561 ggagccgcac gaacacctga agagcttaga caagatctgg agaaggctta ttcgttgata
    19621 ccgggcaaac acaaattgaa ccttcatgct atctatttgg atacagaaga atctgtcgat
    19681 ctaaatgaaa ttgagccgaa acattttgaa aaatgggtag agtgggcaaa aaaagaagaa
    19741 atcggtcttg acttcaatcc gactttcttt tcgcatccaa tgatgaaaga cggctttaca
    19801 ttggctcatc cagataaaga agttcgtgaa tactggatcg aacacgggaa aagaagccgc
    19861 aaaatcgcgg agtactttgg gaaagaaact gggcaaacaa gtatcaataa cttttgggta
    19921 cctgatggga tgaaagataa tccgattgat cgttttaccc cacgggaacg tttaatggaa
    19981 tcactcgatg aaatttttac agaagagtta gatgaacggt atgtacaaga tgcagtagaa
    20041 agcaaactat ttggtttagg cgctgaagct tatacagtcg gttcccatga attttatatg
    20101 ggttacgggt tgactcgtga caaacttgtt tgtctagatg ctggacattt tcatccaaca
    20161 gaagtgattt ccaataaatt atcttcatta gctttattca gcaaaggaat catgttgcat
    20221 gtttcccgtc cagtgcgttg ggattcagac catgtggttt tgatggatga tgaattgcag
    20281 gaaatcgcta aagaattagt ccgtaacgaa ttgttggaaa aaacaaatat cggtctggat
    20341 ttctttgatg caacgatcaa ccgtatcgct gcttgggtca tcggtacgag aaatacacaa
    20401 aaagcactgc tgaaagctat gctggaacca gttgagcgat tgaaagaaat ggagctggct
    20461 tttgacttta cttcaagaat ggcttatacg gaagaattga aagatttccc gtatgccgat
    20521 gtatggaatt atttctgtta caaaaatcaa gttccagttg gtttggattg gctggaagaa
    20581 gtccaggaat atcaaaaaga cgtgttggaa ttaagaaaat aggagtgtgg ctatattgaa
    20641 aaaaatagat attttacaag cgccttatgt gaaagaaatg atcgaaacga cgtcgaatct
    20701 ttatcgcttg ggatgggatg aaagaaatgg cgggaatatt tcttatttac taaaagaaga
    20761 agagatcaca ccgttcttgg atcctgaaaa agtgatccgc cgcatctcga tgatttttga
    20821 tgccagccgt ttagcaggat gctattttat tgtaactggt tcaggaagat attttaaaaa
    20881 tgtagcgagc gaacctgccg agaatcttgg aatcgttcga gttgctgaag atggcaaaac
    20941 actggaactt ttgtgggggc tggaaaacga atgccttcct acaagcgagt tgccaagtca
    21001 tttcatgagt catatcgccc gtttagaagt agacccagat aatcggatcg ttatgcattg
    21061 ccatgctagt catctattag cgatgagttt tacgcatgaa ttagacgaac gttcctttag
    21121 tcgtacgcta tggcaaatgt gtacggaatg cttagttgtt tttccagaag gaatttccat
    21181 cattccgtgg atggttccgg gaacaaatga gattggggaa gcaacagctg aaaaaatgaa
    21241 agaaactcga ttggttttat ggccacaaca tggaatctac gggtcaggaa aagacatgga
    21301 tgaagtcttt ggtttgatcg agacagcaga aaaggcagca gaagtctata cgtacgtcaa
    21361 agcgcaagga ccaatcttgc aaacaatcac ggacgaaaac ctgtggcatt tagcagatgc
    21421 gtttggtgtc actccaaaag caggttattt ggaggaagtt catacgaaag caggtgtctg
    21481 acatggtgaa aaaagctttt tgcatgaaag tttacccaga aaaacaagaa gaatacaaaa
    21541 aaagacatga tgaactttgg ccagaaatgc gtacagcact tcgtgaacac ggggtcatcg
    21601 actattcgat ctatcttgat ccgagtacaa gtttgttatt tggttactta gtgatcgaag
    21661 atgaaaagtt atgggaaaaa atggcaaata catctatcaa tcaaaaatgg tggaagtaca
    21721 tggaagatat catggagaca aatccagatg cctctccagt cagttgggaa ttgatgccag
    21781 tctttgaact gtagcaacaa gcaactgggc aaccggttgc ttggggttct ttcgttttta
    21841 ttgtgaaaaa taatacaaat taggaggaat agaaaatgag taatcgaatg attttaaatg
    21901 aaacatcgta ttttggaaaa ggagcgattg agtcgatcgt ccctgaattt cagcagcgag
    21961 gattcggcaa agcagctgtc attactgaca aaggattgat cgagcacggt atagcaacaa
    22021 aagtaacaga acttctagat aaagcagcaa tcgcttatgc tttatacgac gggatcgtac
    22081 ctaatccaac gatccaaaat gtaaaagatg gagtggcttt tgttaaagag gcagaggcag
    22141 actgtttgat cgcaatcggt ggaggttcgc caatcgatac ggcaaaagcc attgggatta
    22201 ttttgacgaa tccagagttt tcagacgtca ttagtttaga aggtgttgct gatacgaaaa
    22261 atccatgttt acctatatta gctataccaa cgacttctgg aacagcagca gaagtaacga
    22321 tcaactacgt catcacagat gaagtaaatc accgaaaatt tgtttgtgtt gatcctcatg
    22381 atatcccaat cgtcgcgttc atcgacagcg atatgatgat gggaatgccg aaaaaattgg
    22441 ctgcatcaac aggtatggat gctatgacgc atgctattga agggtttatc acaaaaggcg
    22501 cttgggaaat gactgatatg ctgcatttaa aagcaatcga aatcatcggc cattctttgg
    22561 aagcttctgt agatggcgat caaaatgggc gagaaaaaat ggcattagga cagtatattg
    22621 cgggaatggg cttctcaaat gtcggtttag gactggtaca cgggatggct cacccgttaa
    22681 gtgcatggta caacattcct catggcgtag cgtgtgcagc acttttgcca actgtcatga
    22741 aatataacaa agaatatact ggagaaaagt accgtgagat cgctcttgtt ctagggatta
    22801 aaggagcagc tgaaatgtct ttagaagatg taagagaagc ggcttgtggt gagatcgatc
    22861 ggttgagcaa agcggttgga atcccagaaa ccatttctga attaggtgta aaagaagcag
    22921 atattccagc aattgcagaa gatgctttgc gagatgtatg cacaccagga aatccaagag
    22981 aaacgacagt agaagaaatc attgctttat atcaaagttt gatgtaaaaa cgaagcggat
    23041 cttcaacatt aaattgcctg taaagagaaa tggtagttta tatctggata tctcttttaa
    23101 attgatggta tttccgctat aatttttctt ataaagaaat aggagaatat tatatggaaa
    23161 ataaaaagcc ttatggaact gtattgatca aagcctctaa aatactagac tatttagcgg
    23221 aaaaccaaga tgtctctttg cagacgatcg caaagggtgt gggaatgacc tcttctacag
    23281 tcttgaaaat actagatact ttgttgatga tcggctacgt aaataaaaat tcagagaaaa
    23341 actatcgttt aggtgcaaag cttattcgct acgcgaataa aaacattgaa caaatcgatt
    23401 tggtagagtt gactttaccg tttttagaac agctgcagca aaagatcgat gagactatcc
    23461 acttaggggt attggacaac aatgagatct tgtacgtgaa caaactagat ccaaaacatc
    23521 aaacgatccg catgtcttca aaaatcggaa tcacccgacc attatacaat tctgcgatgg
    23581 gcaaagccgt attagcagaa ttcagtgaag agcagtacac tgattatctt gaaaagcatc
    23641 cgttgatccc ttacacagaa tatacgatca ccaatgcatt acggttgaaa aaggaaatca
    23701 aaacggtaaa agaaacccac atcgcatttg acgatgaaga aatcgaacgt gatatttttt
    23761 gtataggagc ctcaatcgtg aaaaacgaac aaatcattgg tgcatttagt gtaagtatgc
    23821 cgaaatatcg tttaacagat gagacaaaag aacaaataat cagtgccctc aagcaaacaa
    23881 aaagcgaaat cgagcaaaga attcaaaaat aatgaaaaaa gcgtttgcaa tttttctttt
    23941 ctgccgtata atatgggtat agatttccaa gttataaaat aaaatttcta aataggaaat
    24001 aggtggagaa gatgaaaaaa attgatattt tatctcgatt gaaaaacgcc ggagtgattg
    24061 cggtggtacg cggaaaaagc aaagaagaag ctttgaatgc ttgccacgca atcatcaaag
    24121 gtggtctaac tggtattgag ttgactttta cagtccctca agcagatcaa gtaatcaaag
    24181 aacttttgtc attctacaaa gaccaaccag aaatagtgat tggcgcaggc acagtattag
    24241 acgctgtcac agctcgcttg gctatcttag ctggcgcaga gtatattgtt agcccttcct
    24301 ttgatcaaga aacggcagag atgtgcaatc tgtatcaaat tccttactta ccaggatgta
    24361 tgactattac cgagatcaaa acagcgctga aaagcggggt agatatcgtc aaactatttc
    24421 ctggaagcgc ttatggacca agtatcattt ctgccttcaa ggcgccgatg cctcaagtca
    24481 atatcatgcc aactggcggt gtgagtctgg acaatatgaa agagtggttc gatgctggtg
    24541 tcgtaacagt cggagtaggt gggaaccttt tagcacccgc agctacagga gattttgaca
    24601 aagtaacgga agtcgcgcaa cagtatgcag caaaaatgaa agaaatcaag aggtagctgc
    24661 ttatgggaaa agtagtgaca ctcggagaaa tcatgttgcg attgtccaca gagcagggaa
    24721 cccgtatcga ttcaagtgaa cgattcgctg cccattatgg cggaggggaa gcaaacgtag
    24781 caatttcttt agctaattac ggacatgaag cgatttttgc tacaaaagta cctgataacg
    24841 cattgggaaa agcagtcaaa aagcacttgc aatgttatgg agtagatacg aaacaggtat
    24901 tatctggtgg atcaagacta ggtacttatt atatggaaac tggtagtggc gaacgcgccg
    24961 cctcagtgat ctatgatcgt gccggatcaa gttttgctga aatggatcat ttggaatggt
    25021 cgctagagga gttattccaa ggaatagata tatttcatgt ttcaggaatc accccagctt
    25081 tgtctaaaaa atggcaaaaa atgacgaaac aggtgataga agctgcaaaa aaagctggct
    25141 gcctgatcag cttcgatatc aactatcgtg gaaaattatg gacacagcaa gaagccagcg
    25201 aagtaatcca tcagctttta cctttagtag atatctgctc agctggaaaa atggatgctc
    25261 tttatttgtt aggtatcgag aaagcgccag aagcagaaga acaacctcta atttattatt
    25321 atcaaaaaat gcaggaaaag ttcccgaata ttcaggtgtt ttattcgacc aagcgtaccg
    25381 ttcattcagc aagtgaaaat gaattgaagg ggacattgtg gatgaaccat gaatatgtgg
    25441 aatcccaagt ccatagaatc accccaatcg tggatcgagt aggtggcgga gatgcttttg
    25501 caggtggcgt gctccatggg attttatcca atatgtctcc gcaagaaatc attgattttg
    25561 ctacggcagc ttctgccttg aagcatacga tccatgggga ctgcaaccaa tttagtcaag
    25621 aagaagtcgc acaattttta gcatgcggct ctggaaaaat cattcgatag aaggagtaga
    25681 agaaaatgca agaaatggaa acacgttata cacacagtcc agaagatatc cgtcattatt
    25741 caacggaaca attgagaaaa gaatttttag tagaaaaggt atttgaacca gggaaaatca
    25801 gtttgactta tacgcacaac gatcgaatga tctttggtgg agtgacacct actgaaaaag
    25861 aattagaaat cacattagac aaagaactag gtgttgatta cttcttagag cgtcgtgaac
    25921 taggtgtgat caatatcggt ggaccaggat tcatcgagat cgatgggcaa aaagaagaaa
    25981 tgaaaaaaca agacggatac tatatcggaa aagaaacacg acatgttgta ttttcttctc
    26041 aagatgctga aaacccagct aaattctata ttagttctgt tccagctcat cataaatatc
    26101 caaatgtaaa aatcagtatc gaccaagtaa aaccaatgga gactggtgaa ggcctgacac
    26161 tgaatgaacg taaaatctac caatacatcc atccaaatgt atgcgaaagc tgtcaattac
    26221 aaatgggtta tacgatttta gaaccaggaa gcgcttggaa tacgatgcct tgtcatacac
    26281 atgaacgtcg tatggaagct tatgtctact ttgattatgc caatgaagat acacgtgtgt
    26341 tccacatgat gggcaaacca gatgaaacaa aacatttagt tgtagacaat gaacaagcca
    26401 ttatttcgcc aagctggtcg atccattcag gtgtaggtac aagcaattac tcattcatct
    26461 gggcaatgtg cggagaaaat atcacctata cagacatgga tatggtgcaa atggatcaat
    26521 taaaataagc ataagggaga gaaaatgatg gaatttagta tggatatgtt tcgtttagat
    26581 ggaaaagtag cattagtcac cggtgctgtc tatggtattg gatttgagat tgcacgctct
    26641 ttagctacag caggagcaaa aatcgtattt aataacttga atcaagaatc agttgatgaa
    26701 ggtatagcgc attataaaga agcaggcatc gatgcaaaag gttatgtctg cgatgtgacc
    26761 gatgaagaag cggttcaagc gatggttcaa cagatcaaag aagatgtagg ttcagttgat
    26821 attctagtca acaatgcagg gatcatcaaa cggacaccga tgatcgaaat ggatgcggca
    26881 gacttccgcc aagtaatcga cgtggattta aatgccccat tcatcgtttc aaaagcagtt
    26941 attccggata tgatcgaaaa aggcggcggt aaaatcatca atatctgctc catgatgagt
    27001 gaattaggac gcgaaacggt cagtgcttat gctgcggcaa aaggcggatt aaaaatgctg
    27061 acgaaaaaca tcgcttctga atacggtcaa tacaatatcc aatgtaatgg aattggacca
    27121 ggttatattg ctacaccgca aactgctcca ttacgcgaaa cacaagaaaa cggtgaacgt
    27181 catccattcg atcaatttat cgttggacgt acgccagcag cacgctgggg cgagccaatc
    27241 gatttggctg gaccatctgt cttcttggct tctagcgcat ctgatttcgt taacggccat
    27301 gtcttgtatg tggacggagg catacttgcc tatatcggaa aacaacctta aaagagcttt
    27361 agtacactgt ttagtggaga ggttgtgaaa tcagcggatt gaacgaatac cgaaggacag
    27421 ctgattaaac atcatttatt cgaaaaaaga ggctgggaca gaagcattta actccaagaa
    27481 ataagaagga attcacgaaa attgcttttc aaatttttgt gaatttcagc ttatttccga
    27541 aggagttgct tttacttccg ccgtttgtac gtgtttagag cgtgagacaa aagtgttctt
    27601 tacttttgtc ccacgctctt ttctgtgcgt cttccatact tcactaagtc gatccctctt
    27661 gcttcgcacc aatccttcac tggtccggaa aagatcagag attgttggtg tagggccgcg
    27721 gtattcgttg cgccgaccat agtataaagc agacgaagct cttcttgcca ttgcttcatc
    27781 agtataatag tttcttctac gccgtgattc atcagatgcg tcagtacggt tcctgaagta
    27841 cccacggcat ttgcgccgag acaaagggct ttaaatatgt cataggcatt gcggatacct
    27901 ccggaggcta ggatttccat agaagtgtct gcttcatttg cttcaagcaa tgaagagact
    27961 gtcgattgcc cccagtcagc taaataactc agttcccgct tggagcgacg ggcgttttcg
    28021 atctgggtga agcttgttcc gcttcgaccg ctgatatcaa ctgtatgaac tcctaaagca
    28081 gctagatcat tgagcgtttc tcttgtcatg ccaaaaccga cttcttttac gatgaggggg
    28141 acgtcaatgg ctgtttgagt ttcttgaata agtactttcc aattggtaaa atcacggtct
    28201 ccctcaggca taaccaactc ttgaggtgca ttcaaatgaa tctgtaaggc atctgcgtga
    28261 aacaatcgga tagcttcttt ggctctttcg acagaagtcc ctgcaccgat gttggcaatg
    28321 attttcccgt gaggatattc ttgtcgcata atcgtataag tatcggctaa agaagggact
    28381 ttcaaggcag cgctgactga accagtggca atcatcaaat ctgcttctct tgcgacgatt
    28441 gcaagatctt ggttgatttt ttttgttttt tcgcttccgc cagtcatcgc attgatataa
    28501 aatgggctgc ttagtgtaaa cccaactgcc tgtgtactta gatcgacatc agaaactgct
    28561 atttgcggca aagggttatg gatgatccgt acgaagtcaa attcgttttt ttgtttatca
    28621 tgaaaggctt tagctagtga aacatgttcg tcttttcgat tcatcggttt tcctttcttt
    28681 gatcgctata gacatgtaac ggcagtggag tgatttctgc tttttcccat gcactcatta
    28741 aaggaagaat gccagatttc tggtcaacaa ttacgattcc gcaatcgccc ccacctgcac
    28801 cagaagattt tgcggctcct tcatactgtt cagctaaatt acacaatttg ttcaaagcag
    28861 gcgtttcgat gacgacccca gtgattgcag ataaatcatg cagtaattgt cggttttttc
    28921 gaatcatctg ttggatcaac gttacattat tttctttaaa ccctttgatc atttcgttga
    28981 cacattctgt actatttttt aagaaaagct gataagccac cattttatct tctctcgaac
    29041 ggtgaacttg atcgaccaaa tcagaagtag aggcagggct acccgtccaa ccaatcaata
    29101 aacgtaaatc ttcaggagca atcaatggct caatggatag acctggccaa tccagggcaa
    29161 gtaactcact gatagaatgc tgagtttctt gttcttggag ccaaggatgg tcgaaggttg
    29221 agaaagcgat ccagccacca taacagctag cagcgatgtc gccgcaggaa ccattatctt
    29281 gaactgctaa attggctagt gctgcaatct tgaaaatctc caactgagat aaattcaacg
    29341 cgtaaaaaac attcaaggct ttgaccgttg caacggtcac ggcaccgcta gaacccaatc
    29401 catatttccg gccatttgaa ctgtctaact cacttgttac tttcagatca taaaaggata
    29461 aaagaatgtt tttttcttgt gcatactttt cagtcaagcg aatagcagca aggatataat
    29521 gaaaaggatt ttcccgaata tctaaaacta attctccgtt gcgtcttgtc caacgtacag
    29581 gcatcccact atattgtgca gattggatac ttccgacttt tcgtgcagat tctacagtga
    29641 ctgtcacgaa ttgatcgact gcagcgataa ctgctggatg gcctgtttca acaactgcat
    29701 attctccggc aatatagagt ttgcctggtg cagatacttc aatcataaaa atctcccttt
    29761 attcaataat cgcaattcct ggaccagcat gtgcagtaat tacttgttct ttgctaaata
    29821 atttggtaaa tgtttcttgt acctcagata aatggctgtt ttccactaaa actttgacat
    29881 tagggccagc atccatcgta aagtagcatg gaatgccttg ctttctcaat tgtcgcaccg
    29941 catccatcgc ttttaagctg tcaggagacc agtaagtgaa tggaggctgg gcagctaaag
    30001 tcgttccatg catttttagt ccgtttcttt ccatcgtttc tccgagaagt tggaaatctt
    30061 ttgttttgat tgcttgtttc aattgatata gatccccttc aacggaatct aaccagcctt
    30121 gataaaaact ggatgtttcg actgtccgac gcatcccatt tctgctggac acttcttttt
    30181 tctggtcgtt gatcaaaacg aaaaccattg ctaaatcgtc ttcgaaagaa tcggaaggga
    30241 ctggcttagc gtaagaactt aagtcgtcat ggcctttttc ccattcgacg aaaccaccga
    30301 aaatacttcg gcaagctgaa ccagacccgc gtcgagcaaa tcttgaaaga gagagatcat
    30361 ctaatccaag cttaagagca gtattgcaag cgcctgctaa agcagctagc ccgctggcag
    30421 aggaggctaa tccagctgcg gtaggaacga aattctgact gattactgaa gcttttagtg
    30481 agaggccggc ttctttacga aaaaggtcaa gaaactgact gacttttttt gttgcttttt
    30541 cgtcttgcaa ggtgccatct agataaaatt catctaccat atagctatca gaaaagatga
    30601 cttctgtctc tgtataaaat gcatccaatg ttaacgaaag gctgttgttc attggaagga
    30661 tgagttcttc atttttctta ccccaatatt tgattagagc aatgttggta tatgcgcgtg
    30721 ctttgccttt aaacataggt atgtactcct aatccttgta tccaagtttc agcagcaccc
    30781 gcatcttcaa gtgcttgact gatttcttgg gcttttgttt ttgtttgtgc taatgcaatc
    30841 atacagccac cgcgtccacc gccagttaat ttggcaccca atgccccggt atcttttgct
    30901 gtttggatca atagattaag aaaatcattg ctgattgtca gcttttccag aagtgattgt
    30961 gattcatcca ttgtctgtgc caacgtttct ggtgaatttt caatgattgc ttgttttgct
    31021 tgcttcgtca agtatcctaa tttttggatc atttgtccag tttcatgagg ctgggtttca
    31081 aagaggtgag cgacatcttt gacggcttct cttgtttgtc ctttgattcc tgtatcagcg
    31141 acaatcaaaa aagcatcgat gttcaaagaa aagtagtcga aaggatgccc ttttgtaaaa
    31201 taaatcggct gcaagctgct agtagcggct gcatcgattc cactaggatt accgtgggcg
    31261 attttttccg aaagctggac attttctaat agtatttcac gagacaaagg aaatgctaag
    31321 taatcataaa aagcacgagt gactgctgtg gcgactgcag cgcttgatcc cattccacgt
    31381 tcagcaggaa tcgtgctttc aatggtcagt tgcaagtttt tttggatgtc atgctgtttt
    31441 tttaagtgaa tgaataattt tttgatattt tttaatgcat gaggagcttc ggctaaattt
    31501 cctgaatagt aggaagaaac cagttgatcg tccattgcat ccagctcttc aaggaatgcg
    31561 gtgacttttg ttgcatagaa aggaaaggca atcgctggtt ctccataaac aaccgcgtgc
    31621 tcgcccatca atatgatctt tccgcttgat tctccttggc catagtttgc cataatctaa
    31681 ctccttctca cgtaaaagtg atttttaagc aaaaaataaa gcgcccaaaa cgagttgcgc
    31741 tgcttcacga atttttttgt ccactaaggg tctcaaaaaa cattcctcct ttattttact
    31801 aaaaccatct cagaagtaaa actaagaata cgttttctaa agaaaaaaca cttttttctt
    31861 aagaattttt tgactttttt tcttctttga ctagaaaaaa atacaattga cactactaga
    31921 tattgggggt atatttaaaa aggttggagt taaacacaat atttagtgat gaagtgagct
    31981 ggaggtaaat gagcgtgatc gttttagcag gtacaattgg tgccggaaaa tcaagtttaa
    32041 cagaaatgat ggctgaacac tttgatagtc aggcatttta tgaatcgatt gatgataatg
    32101 aagtcttgcc cttattttat gcaaaccctg aacagtatgc ttttttgctg caaatttatt
    32161 ttttgaataa acgttttgca agcatcaaac aagcaatgaa agatgacaat aatgtattgg
    32221 accgttcgat ttatgaagat tcactgcttt tccatctaaa tgcagatcta ggaagagcaa
    32281 cagaaacaga agttcgtgtg tatgatgaac tgctggaaaa catgatggaa gaacttccct
    32341 atgctgccca taaaaaacat ccggatttat tagttcatat tcgtgtatct tttgatacga
    32401 tgttggagcg tatcgaaaaa cgtggtcgtt cgtatgaaca attgtccttt gatccaagtc
    32461 tatacgatta ttacaaagaa ttgaacagac gttacgatca atggtatgaa gaatacaaag
    32521 aaagtccaaa aatccaaatc gatggagacc gctataattt tgtggaagat cctcaagcaa
    32581 aagaagaagt cttgaaaatg atcgaagaaa aattagcaga gattcgccaa accaaagtag
    32641 ccatttgatt tacagttgct caaataaagg gtaaaccttt atttgagcga cttttttctt
    32701 tatactggaa acaaatgtca ggaggataga gtatgcggga aaaacactat tttaatcaag
    32761 accgtaattt ttggatcaat gtacagcaaa acgatgtgct agctgttaaa aacttaaaag
    32821 aagaatatgg cattagtgac gagatgctga cttattctct agataaaaat gaacgggcgc
    32881 gcgtagagta cgattctttt gatgaagcgt tactgcttgt atcaaatgtt ccgcaccagc
    32941 aaaaagtcga taatcattat gaaactagtc ctatcgcttt tattttaaaa gaagacggtt
    33001 tgtttacatt taccacgccg aataccgagt acgtgattcg actaattcga tcgcttttgg
    33061 aacgaatgcc agacatgagt gtatacagtt tattgtttcg tacattgttt ttgatttctg
    33121 attccttttt tcctttaatc gaggaagtga atagtgaacg tcagcggctt aatctgaaat
    33181 taagagaaaa aacaacgaac aagaatctgc tgcaactttc agatttagag atcggtttgg
    33241 tttacttagt tacaggaaca aaacaaaatg tagtactttt agaacaaatc aaggcattgg
    33301 ctatttatcg caagttgtca gaaaaggaaa aagaagagtt ggacgatgcg ctgatcgaag
    33361 cacgacaagc agttgaaatg acgaacttag cttcgcagat tttagaccag ctctctggca
    33421 cttataataa tttgctgaat aacaacttga atgacacgat gaaatttttg acggtctggt
    33481 cgctgatctt gaccgttcca actattgtga caggattctt cggaatgaat ctccagttac
    33541 cctttaccca ttccgttttc ggatggggaa tcgccttgat catcagtttg gtcttatcta
    33601 tttggatgct tattgcactg tggcggcgga ttcgttgatc tagtctttga tctgcaaacc
    33661 aagggcttgg gcgatcacaa gtgcttgctc ttggttgacg attagtcccg ccaaagaatc
    33721 ttgagataaa gcgattgctg tgaagaaatt agtcgtaaag tctaatccct tcagagaagt
    33781 tcgaaaccag ttcgaaccgg tcaactgatt gtcagacaaa aaaaggtttt tccaagtgac
    33841 ctcataaaat tcgctgtctt ctaattgaca atgatcgaag gagacagctt tcaagtttgt
    33901 actactaaag gaagccatcg aagcaataca atcagtgaaa gtacagtctc gaagataact
    33961 ttcggcaaaa ttcgtacctg ttaatttaca ttgatgaaac acgacttggt ggaaactgcc
    34021 accaatccac tccagattgg aaaaatcaca tttttcaaaa atgacattac tgcattcaaa
    34081 atgacgtaaa actgtttttt gcatcgtaag tttttggata tgactctctc ttaataccat
    34141 atttttggca tcgagatagc tttggtcacc cccgttgatc agaagaccag agaagatctc
    34201 ctcatcttct aaataaaact ctccctttgt aagaagagga agagaaggtg gaataggttc
    34261 gatttttttc atgtgggttc acctcgtttt tctttagtat agcaaagaag cgggaatcac
    34321 tgctagaaag tctgctaatc taatcatttt cagaaaagga agacaaactg tatgaaaaac
    34381 attgacaaaa agattagttt ttgctatact gtgatggttg agaaataaaa gcagaagcac
    34441 ccgcttctcg ccttagttga taatgtcact gggctagata gttttcactg gttctattag
    34501 gtgaagtacg cgcgggttct gtaagagaac tcgttttttt attgccgttt attcggtaag
    34561 cttttctttc tctcataata tttggaggtg aatgaccata gcaaaggata tgatggttaa
    34621 cgacggcatt cgtgcacgag agttacgatt gatcggttca gatggtgagc aattaggagt
    34681 taagacaaaa gcagaagcat tgaatattgc agaacaagca aacttggatc ttgtgttagt
    34741 tgcccctggt gcgaaaccac cagttgcgcg aatcatggac tacggtaaat accgtttcga
    34801 acaacaaaag aaagaccgcg aagcgcgtaa aaaacaaaaa gtgatcaatg taaaagaagt
    34861 tcgcttaagt cctacgatcg acttgaatga cttcaataca aaacttcgta atgcacgtaa
    34921 gttcttggaa aagggcgata aagtgaaagc ttctatccgt ttcaaaggcc gtgccattac
    34981 ccataaagaa attggtcaaa aagtcttgaa tcgcttagct gaagaaactg cggatattgc
    35041 aacagtggaa caaaaagcga aaatggacgg acgcagcatg ttcttgacgc tggcaccgaa
    35101 aaacgacagt aagtaatttg aatgactaac tggctgttgg acagccgata gtcggataac
    35161 gaaagatttt gaggaggaaa tatagtcatg ccaaaacaaa aaacacaccg cggatcagca
    35221 aaacgtttca aacgtactgg taaaggcgga ttgaaacgct tccgcgcgtt tacaagtcac
    35281 cgtttccacg gcaaaacaaa aaaacaacgc cgtcaattgc gtaaagcaag catggtttct
    35341 agtggcgact tcaaacgtat tcgccaacaa ctagcaaaaa tgaaataaga agtacaaata
    35401 acagaatctg aagatttatt tttattagga ggaattatac atggcacgtg ttaaaggtgg
    35461 aacagtaact cgtaaacgtc gtaaaagagt gctaaaatta gcaaaaggtt actacggttc
    35521 aaaacacact ttatttaaaa cagcaaaaga acaagtaatg aattcataca actacgcata
    35581 tcgcgatcgt cgtcaaaaga aacgcgactt ccgtaaattg tggattgctc gtatcaacgc
    35641 agcagctcgt atgaatggct tgagctactc aaaattaatg cacggtttga aagttgctga
    35701 aatcgacatc aaccgtaaaa tgttagctga cttggctgtt aacgatgcag cagcatttac
    35761 tgcattggct gaccaagcaa aagaagcttt ggctaaataa gctaaacaat tataaagagg
    35821 aaagaagata acgaaaagtt atgttctttc ctcttttttt atttacaatc ctccatcaaa
    35881 tgaaacagga caataacgta taagtctaaa atagcataat taaggttttt taattgaaaa
    35941 ctgaacattt atggtcaccc tttaatgaaa gcgctaacta cataagttag aatgagtttg
    36001 actgatatat tagtttgctt atcagaaaaa caaaatggac ggaggaataa catgagtgat
    36061 attattattg gtattttgtt agttatctca ttctttttca tggtctggta ctgtgtaaaa
    36121 ggctacaact tgatggtcgg ctttgccatc atggctactg tatggatggg attagcgcta
    36181 gtcggaaaca cgttttcacc aaacccggcg atggaagggc aaggagtaat tgatgtgttg
    36241 acgcatatct atacgacggg gccagctgag tacgccaaat cgatcttggt aaatgtcttc
    36301 tttggtgcct ttttcgggcg tgttctagta gatagcggaa tcgcagctac cctgattcga
    36361 aaggtagttg aacttggagg ggacaagcca agaatcacga tgagcttact atgtattgta
    36421 accgctgtta tattcatgtc gatgacagga atcggaccag tgatttctat tgcagttatt
    36481 gtgttgccaa tcttgatgtc attaggtatt tcagtaccgg ttgcactgtt ctcatttatg
    36541 ggctcgatta tggctggaat ctttgctaat atcgtcaatt tcaaacaata tcaaacgatt
    36601 tatgctggtt tcaatccagc ggctgaaagc tatacttata atgactattt ccaaattggt
    36661 atgattggga tgattgtaag cttagttgtg gtactaacgg tcgctaatat atcaatgaac
    36721 aaaaagaaac gctatgcaat ggcagcaaac gtaccagctg aaggtggcga cgcaccaatg
    36781 atctcatggt tagccgtatt attaccagtt ttaggggtcg ttcttttaga tcttccaatc
    36841 atcttaggtt ttattctagc aggtatctgg gcattgctgt ttactggaaa attgcgcgga
    36901 ggttataaag aaatctgtcg tcagtttgcg aaattattta cagatggcgc agtagatgtt
    36961 gcgccaatgg ttggtttctt gatgacctta gcgatgttca ataattcagc tgcgtatgct
    37021 tctccttatt tttcagctat ttttggagat tggataccgc aatcaccatt agtcttggca
    37081 atcgtatttg ctatattgac accactagga tttttccgcg gtccaatgaa tctagtcggt
    37141 tcaggctcag ctattttagc tgtcgtatta gctgttaatc caacgatgtc gccagccttt
    37201 ttgttcccgt tatttgcaat cacaacgatt gctcctcagc atttagatat tacacaatct
    37261 tgggttgctt ggggattagg ttatacaaaa gtaacttctc gagaatatat gaagaaatcc
    37321 atcccaactg gttggatcat cggagcgatc ttatgcctga tcacgttctt attgtacggg
    37381 aacgcctagt aaacaaaacg tcgataaaaa cgattagatg aatggaggaa aagaaaatga
    37441 aacgttttgt gcgaatggga attgatgttg gcggtacaca tacgaaagca gtcgcaatcg
    37501 ataatgcgac gcacgaaatc atcggaaaat cttcagtgaa aacaacccac gatgatgtcc
    37561 gtggagtagc cgcaggtgtc gttcagtctt ttcaaaattg tttgctggaa aataatatca
    37621 gtccagaaga tgttgtgttt gttgcacatt ctaccacaca agcgactaat gcactgattg
    37681 aaggagacgt agcaaaagtc ggcgtaatcg ggatggcaaa aggtggatta gaaggttttt
    37741 tagcaaaacg acaaactaga ttgaacgata tcgatttagg gaataagaaa aaaatagaga
    37801 ttgtcaatgc attcttacct gtcaaacact taaatgtaga ccgtgtttca gaaacgattt
    37861 cttctttaga aagagaaaga gcggaggtct tggtttcttc tatggcattt ggagtagata
    37921 atggggaacc agaacgagtt gtttatgaag cagcatcggt aaaatcgatc cctacaacga
    37981 tggcttctga catcacaaaa ttatatggat tgacaagaag aactcggaca gcagcaatca
    38041 atgcatctat tttaccaaaa atgctagata cggcaacctc tacagaagat tccgtacgag
    38101 aagcaggggt caatgtttct ttgatgatta tgcgcggaga cggcggagta atggaaatca
    38161 atgaaatgaa aaaacgacct gttttaacca tgctttccgg tccagcagca tcagtcatgg
    38221 gctctttgat gtacttgaga gcgtctaatg gtgtttattt tgaagtaggc ggaacaacaa
    38281 ccaatatcgg ggtcattaaa aatggacgtc cagcaatcga ttattcaatt gtaggtggcc
    38341 acccaacata tatctcttca ttagatgttc gggttctagg tgtggcaggc ggttcgatgg
    38401 tacgggctaa tcagtcagga atcatcgatg tcggtccacg ttctgcacat attgccggtc
    38461 tagattatgc agtatttacg gagacagaaa aaatcaaagg tcctaaggtt gaatttttct
    38521 ctcctaaaga aggagaccct gctgattacg tcaaggtagt gatggaagac ggagaagaag
    38581 tgactattac aaatacatgt gcagccaatg tccttggatt agtgcaagaa gaacattttt
    38641 cttatggaaa tgtcccatct gcacgaaaag ccatccaagc attagctgat tattgtcata
    38701 cgacggttga agacatcgca gaacagatca tggaaaaatc ctatgctaag attgaaccgg
    38761 tgattttaga attggcagac aagtatcact tggagaaaga tcagatttct cttgtaggtg
    38821 tagggggcgg cgctgcctca ttgattactt actttagtaa taaaatgggt gtgaaatatt
    38881 cgattcctga aaacgccgaa gtgatttctt ctattggtgt agcacttgca atggtccgag
    38941 atgttgtaga acgtatcatc ccttcgccaa gtaaagaaga tatacgatcg ttgaaaaatg
    39001 aagcgatgaa taaagcgatt gaatcaggcg ctacaccaga atcgatcgaa gtccacgtag
    39061 aaatcgatcc acagacttca aaagtaacgg ctatcgctac tggttctacg gaagtgaaag
    39121 caaccgatct aaccaaggag atcacaacag aagaagcact agagcttgct gcagaggata
    39181 tgcgattaaa taaaaatgaa gtttgcttat tggaaaatac acctttcttt tatgtatgcg
    39241 gcgaacagaa tcgttcaaaa aatgctggaa gtcttcggat catcgatcaa aaaggattta
    39301 tcaaggtcca acgtggacat gcttcatgta tgaaaacaac tgcagccaat tatatgacag
    39361 ctgtcgaaca actttgggaa gatatggcag tttatcaaac tgaattgatt gcccgaccag
    39421 aattttatct ctgcttagga gcaagagtct ctgattttac agcgacggat ctggaacaac
    39481 tacagctttt gatggatctg gaagtatcta ctatggaacc ggaggaagaa gtgatcgtcg
    39541 ttgccggaaa tatcaaacaa acataagtta gaagagttac taaacgaatt acaacagatc
    39601 cccgaagaaa tttggggatt ctaccagttt cggcgagatt tattttggaa aaagattcct
    39661 ttgtccaagc agaaaattct tatacaacaa tcaatcgatt gtggtatcga aacggcatgt
    39721 agcatcaaaa aaaagtaccc ttttgccgat gtaggagaaa tttgtgaaca aatggctgtt
    39781 ccaatcgttt cctgtgaatc agagcaaata aacgaacgaa tcacttttgc aacttatgca
    39841 gaagatgaag ggattcgatt gatgacggag ccgttagaaa aattaaaatg ttcaggacta
    39901 gcttcgatct ctaaagaaac agcgcaagct ttgattattg gacatgaact atttcaccac
    39961 atcgaagctt ctgttaaggg aatttatacg caaagcgaaa aaattgtgct gtggcggttg
    40021 cctttttata cacatcaatc aaacattcgt gcattgagcg agatagcagc gatgagtttt
    40081 tcaaaagaga tgaatcaaag cgatttttcg ccttatgtat tagaggcagt cttactttgg
    40141 ccatataatg aaattcgtag ccaagggatc ttagaagaaa taaaaaaaat agaaaaaaga
    40201 tgtacggagt atgatttaga ttacaaataa agagactgtg acaaaagtcg tgtcacagtc
    40261 ctttttttcc gaataaacgg tgttctcctg tcaactcctc ggtcacaagt caaaatattc
    40321 aacaaacatg agaagctgtt ttttgaaatt gttccttgtg actcggagat gaacggcagg
    40381 ctcacgacct cttggaaaac ggtgttcaaa agcttgcatc tgcggtaata agtccagcca
    40441 agttaaaaac ataagaagct atttttactt ggctgttctt attacttgat gcagggcagc
    40501 tttttcacaa cctctcaata aacggtgtgc aatcagctga ccctcggtat tagctcaaaa
    40561 aaaacggcaa aatatgagga actattttgc cgtttctttc tctaatactc aggtcaaaac
    40621 gctgattcca aaacctctta tttgatgggt ctgtcctgaa tatcttcaaa ataatcgggg
    40681 taattatgaa tcacgtattc ttgctcctcg ataatcatat gtaaatgcat cgtgcaaaga
    40741 aatccgactt catcaaagtt atgatcaatc attgattgaa gcattgtctg atgttcatct
    40801 aatactcgac cccagtctaa ttctgaaatc gtcaaacgta accatctgaa acggttcaag
    40861 tgcgtactat aactttctag ccaatcccaa atttctcgtt ttccagcaat ttcataacaa
    40921 gttcggtgaa aatcagtatc caaatcaaaa aaagcttttt tattttgagc gattactgcc
    40981 tgatcggttt gttctagtat tttttctagt ttaacttgat cttgcttggt cattttcgca
    41041 ctgcattctt gcaggatcgg tttttccaac ttttcccgcg tataacgggc taatgaagca
    41101 gatcggatat cgatttttga aacataagtg ccggactgtg gaatggtttt tacaagctct
    41161 tgattgcgca gttggatcag tgcttctcga atcggtgtac gcccgatagc tagttgttct
    41221 tctaacactt tatcggagat tttacttcca ggtgctaact cggaataaat gatttgttta
    41281 cgtatagatt cataagcttg ctgttgcaaa ttattgataa ccatttaacc ttcctttcta
    41341 tgcagatata atctattata acataaatcg cttacaaatc gtgtgggcat aaaaacacag
    41401 tctgcaaaaa aagccctgat aggcatgcct attagagcct cgaaaagaaa aatattgaat
    41461 caatctggtc gtacctcttg gatcggtttg acacgaccgc cgattctttt agcaaaagct
    41521 tcggattctt ttttgtcttt gaaaatgagc agattgtcta agtttttttc ccgagtgcga
    41581 cagccagttt tatcgatgta accgtgcatt actttaacga catacatggg gatcacctgc
    41641 ttttttcttt tcattatacg aactactcga cacaatacaa gaaaaatgct tagacggtct
    41701 ttattaagaa tttacatcat ccaaagaagc gtacgcttgg aataactgat ctaactccgg
    41761 attgactttg ctcagcttca ctaatcgttg cgaatcagaa agtaaaaaac agtgtttact
    41821 actgccagta gtttttaatt ttttgtcttc agttcccaca atttcgtagc taaaatccaa
    41881 ccgtgtcccc gtatactttt ggatagttgg atggatgctc actttttctc cgtaatggat
    41941 catttcttta tagctgcaat ttacttccag aacggggatg atgatcccag attcttcgat
    42001 ttttttatag ggaaacccta gatgtaccaa taaggctacc cgagcctctt caaaccagcg
    42061 gatataattg ctgtgatgaa taatccccat ttgatctgtt tcataataaa aaggttctcg
    42121 cacataacct gtaaatttct ccatgactca tgcctcgttt tccattgatt ttttacaaaa
    42181 ataattcatc catttcggaa gtgcttcgct gatttgtgtc ggcaaaacaa tatattgttc
    42241 ttttgccagc tggtctccaa tgaaactatg aagataaata gctgctgcaa tcgtttggtc
    42301 attttgagga aactgggcta aaaatcctgt gatcatccca gctaaagtgt cacccatgcc
    42361 gcccgttgcc atagcagcag aacctaaagg attggtgtag aagtgctggt gaccataaat
    42421 ttttgtctca tgacttttca aaacgagcac agcaccgatt tcctgttgct tctttttgtt
    42481 ttctttatcc cgttgttctt gtatcggtag agaactcaac cgttgccact ccatttgatg
    42541 aggtgtaagt acagtttgtt cgggataggg tagcaaaaga tgattagcag caagtaaact
    42601 taaagcagag ccatcaatca ccagccattg ttcttttgat tggttttcta gtacttgttt
    42661 gaaacgttcc aaactcttag aagaagtacc caatccggga ccaatcaaga gtacatctgc
    42721 ttgctttatt acggaaagaa actggtcagt atccgtccaa actacaatca ttgcttctgg
    42781 cagatgactg tgaagagcac tccgattttt ttcatcagtt actacagtcg tgagacccgc
    42841 tccgctgtgt acggcagcta aagcactcat aatgattgct ccgccatatt gttcattgcc
    42901 gccaatcaaa acgatacgtc caaatgttcc tttatgtgaa atttttggac gaggtgtgat
    42961 gactcttttc actagttgtt cgtttatcag catctaaaaa cctcctttta ctcattatag
    43021 cgtatatttt ttttagagaa aaacagataa gaaaaggaat tgtcagattt tttgaactat
    43081 ttttttctgt aatttgtggt atcatgaaca cgaagactta aataagtgga ggattaactt
    43141 tatgacaatt gattggcaaa aagaagtaga agcacgtaaa gaagacttgc ttgaagactt
    43201 gaaaaatctt ttacgtgtca acagcgagcg cgatgactca aaagtaacac cagatgcacc
    43261 atttggacct ggacctcgcg acgcattgaa acatatgtta gcttatggcg aacgtgatgg
    43321 atttaaagta aaaaatgtcg ataactatgc agggcatatt gatcttggcg aaggagacga
    43381 aacgctaggg atatttggac acatggatgt cgttcctgca ggagatggct gggacacaga
    43441 tccttatgaa ccagtaatca aggatggaaa gatctttgca cgcggatcaa gcgatgacaa
    43501 aggtccaagt atggcagctt actatgcgat gaagatcatt aaagaacttg acttgaaact
    43561 atcaaaaaaa gttcgcttcg tagtcggcag cgatgaagaa agcggctggg gcgatatggc
    43621 ttattatttc gaacatgaag aagaaccaga ttttggtttc tcaccagatg ctgaattccc
    43681 aatcatcaat ggtgaaaaag gaaatgtttc tttagcttta cgcttcaaag gcgacaatgc
    43741 aggagattat gtcttgaaat cttttgtttc cggacttcgc gaaaatatgg tgccaggaac
    43801 agcaactgca gcacttcaag taccaagtgc agatgcagct atcgcgatgg aagaagcatt
    43861 ttaccaattc atcgaagcaa atccagtaag cggaacgatt gaagcggaca atacgtatgt
    43921 aaaaatcgaa ttagttggta aaggcgcaca tggtgcaagc ccacaatctg gtatcaatgc
    43981 aggttctttc ttggcattgt tcttagataa ctatgaattc ctaggatctg ctaaacaatt
    44041 tatccatgta gcagctgctt atgtccatga agatttttat ggagaaaaac taggagtcgc
    44101 ttatgaagat gaaaaaatgg gcaaattgac aatgaatgct ggactatttg cttttgaaga
    44161 aaatggtaca gaggaagcga acttcatcaa tatgaatttc cgttttccaa aaggtgtaac
    44221 agtagacgga ttgcaaagtg acatcgaaca aacagtgggg caagaaggcg caacagttac
    44281 tcgaggtgct cgcgtaatgg aaccacatta cgtaccaatg gatgatccat tggtggctac
    44341 attattgcaa gtctatgaag accacactgg agaaaaaggc tacgaacaaa tcatcggtgg
    44401 cggaacttac ggacgtttgt tgaaacgtgg cgttgcttat ggagcgatgt tcccaggata
    44461 tactgataca atgcatcaag caaacgaatt tatgagtctt gatgacttgt tcagagcaac
    44521 agcaatctat gcagatgcca tctatcgttt ggcgaaataa ttaattaaaa agaggatcaa
    44581 gaattgcaaa ttatttttgc agtcttgatc ctttttttac tttctactgt ggtattcatg
    44641 ataaacatga tatagattca attcatattc tttcttagcg ttcgtgacga ctgtatccaa
    44701 aatcaaccct gttactaatg aaagaagtgc taaagtcatc aatccagtac ttaaaatcgc
    44761 agaagggatg cgtgtaataa agcttgtcag catatattcg cgaatcacag gaatccccgt
    44821 gaccaatcca aataaaaaga agaagatggt ccaaatccca aagaaaagca aaggcttata
    44881 atctttaaac attttaataa tcatcatgat cactttgaat ccgtcagaga atgtattcaa
    44941 ttttgattcg ctgccttcag gacgatcacg ataatcgatt gggatttcaa cgaacttgaa
    45001 ttttttatct aaagcatgga tcgtcaattc cgtttcgatt tgaaaaccag aactcataat
    45061 aggaaaactt ttgacaaaga tacgattgaa tcctcgatag ccggtcatga catcaagaat
    45121 ttttgtttta tacattctag taattgtatt tctaacaagg ttatttccaa aatcgtggaa
    45181 aggtctctta ttctcatcaa agtaggttcc atttgatagg cgatcaccaa tgaccatatc
    45241 tgcttcacca gaacgtaatt tctcgagcaa accatgtaca gcttctgcag gataagtatc
    45301 atcgccatct accattaaat aatagtcggc atcgatatca aagaacattt ggcggatcac
    45361 atttcctttt ccttgacgag gttctttttt tacgattgct ccaccttgaa cggccaattc
    45421 gtatgttcga tcggtcgaat tattatcata gacataaata tctgcttctg gtaattctcg
    45481 tttaaagtct gcaatgactg ttgaaattgt tgcttcctca ttgtaacaag gaatcagaac
    45541 agcaattttt tcttgttgtt ccatttttca ctctccttaa ctatagaaaa caaaagctaa
    45601 attaaaaata cctcataatc aaaggaaatg ctagtttttc ccgctaaata tcatttattt
    45661 aaaaagaaaa tactggaata tatgtttgga aagctctatc taaaaaacca cccactacaa
    45721 aagaaggaca tgatacctct cttttgaata gtgggtgcgt attcgttctc tcactttttt
    45781 gacgtattaa tctgttgcac ctttttttct tgaaatttct aatacggttc ctgtatgagc
    45841 atctgctaaa aattcataat aaacagtttc gccatcttct attcgagaaa gacctccccg
    45901 ataagcactc gaccgaacgg cgaatttcct aataggttcc ttttcaaaag agatccaaga
    45961 accttcgatt gcaccttctt ttagaaaaga tgacttgata ttttcaagta cttggtctgc
    46021 tgacaatact tttttgcgat gataccaaat cgttgaagct accccgctca ataatcctag
    46081 accgattcca actgctaacc cgcctttaaa atagcttagt tcgctttctt catacatgtg
    46141 gacatacctc cttcttctca cttgttactc cttgtgctta ttttaccaca ctctcatatt
    46201 ttctttgaaa taaataaccg ctaccagaaa aaataagcta taataaatac gatcggtctg
    46261 cagaaaaaat catattttat ccgcagatca atataagtct gagaggagtt tagtctgaaa
    46321 tttagacgaa tagcatatgg aagaaaaaac atttcaacga atcaaagagt taacagaatt
    46381 acaaggaaca agcggttttg aacaagatgt tcgcgcttat atggaaagtc atatggaacc
    46441 gctggtagat gagttacagt tagatggttt gggcggcatt tttggtctgc gccatcatga
    46501 agaagcggat gcaccccgtg taatggtcgc agcacatatg gatgaagtcg gattcatgct
    46561 gacacaaatc caagaaaacg ggctttttaa agtcgtacct ctaggcggct ggaatcctta
    46621 cgttgtttct gctcagcgtt ttacacttaa aacctctact ggtaagaatt atccatgtat
    46681 ttcttcttcc gttcccccac atttattgcg aggaacaagc ggacaaaaat cagtagaagt
    46741 aaccgatatt ttgttcgatg ctgggtttga atcaagagaa gaggcaatga gttacggtgt
    46801 ccttccagga gacacaatcg ttccttacgc tgaaacgatc aaaacagcca acggaaagaa
    46861 tattatcagt aaatcatggg acaaccgcta tggctgtaca atggtattag aagctttaga
    46921 agcgttgcaa aatgaaacat taggtcatac attgattgca ggcgcgaatg tccaggaaga
    46981 agtaggcttg cgtggttcta aagcttctgt caataaattc aagccagatc tgttctttgc
    47041 agtagactgc tctgcagcag atgatacagt gacgaaaaat ggcacattcg gacatttagg
    47101 agaaggtaca ttgatgcgta tccaagatcc aggtttgatc atgcttcctc gtttgcgcga
    47161 gtacttgctg gatatcgctg aaacaaacaa tatcccttat caatactttg tttcaaaagg
    47221 cggtacagat gcaggtgctg ctcatacaca aaacgaagga atcccaagta cagtgattgg
    47281 cgtagtggga cgttatatcc atacgcatca aacgatgttc agtattcgcg attttgaagc
    47341 tgcacgagaa atgttgattc aaacactgaa aggtttggat aaatcaacag taaatacgat
    47401 cgtatacgga aaataatgcg atagtgaaac tataaaatct ggcaaaagat tgctttttgc
    47461 cagatttttt ttataaaaag aggatcaatg tttgttagtt cgaaagaaag gtgtataatt
    47521 taattgaaaa atacataaac agaaagtaga ggacaaagaa tgattatccc aaatagttta
    47581 gaagaattag caggctacgt agaaactgga aagagtgtat ttttctttac tgccggctgg
    47641 tgcggagact gccgttttat caaaccgcaa atgcctgaaa ttgaaaatga cttttctgat
    47701 tggcaattta ttgaagtaga ccgtgacaag tacatagatg tagccgctga atggaacatt
    47761 tttggtatcc caagttttgt cgtgatccaa gacggaaaag aattaggtcg tctagtgaat
    47821 aaagatcgta aaacaaaaca ggaaatcgaa tcgttcctag aaagtgtaac aaaaggctga
    47881 catctgttag gaggggtcaa gatgaatcaa gaatataaga atattttagt aggtatcgac
    47941 ggtagtgaac aagcacttgc tgctttcaaa aaagcggtag aagtggctcg ccgtaataat
    48001 gggaaagtat atgtagcaaa cgtaatcgat cagcaatttt ataactttat gggctatgca
    48061 cctattgatc aaaatctagt cgatcagcaa actgaaacag ccaaggaaat gatcgaagaa
    48121 tgtaaagaat atgggaaatc tgttgattac acaaatatag aaggaattat tgcatatggt
    48181 tctgttcgtg aatccatggc agtcaaattg ccaaaaaaat atgagatcga tctaatcatg
    48241 gttgggcagt caggtctaaa tgcagtcgaa cgctttatga caggaagtgt agccagctac
    48301 gtgatacgtc attcaccttg tgatgtcttg atcgtttctg acgaagaaga acagccaagt
    48361 aattaagcaa gtggaacttg tacgaccttt ttaatcaatt aactaaaaca gtaaagggac
    48421 tgtgacaaaa gtcttgtcac agtcccttgt tacgaataaa tggtgttcca gaagaggctt
    48481 cttcggaaat aaagcatgaa aaaaatttca tgcagtgaat gcaatttttt gttaagataa
    48541 atctcagcaa aggataatgg aggaaagaac atgatttttg cttataacaa agcacacgtc
    48601 ggagacacct tgatggttat tatagccgac gataaaggaa cagaaaacac tgttgaacgc
    48661 aaatggaatg ttgctcggat caaagatgaa caaggtcaag ttgttgcttg gaactttttc
    48721 catatctccg atcatctaac aatcgaaggg aacggccaag taagcttaac agatgaggaa
    48781 ttagcgaaat tgaatcgatt gatcaaagaa gcaggattcg aagaacagct tgaagctgat
    48841 catgaaccga agatcgttgt cgggtacgta aaaacatgcg tcccacatcc tgattctgac
    48901 catttatcga ttactgagac agaagtagac aatggtacag tattgcaaat cgtttgcggt
    48961 gcacccaata tcgaagctgg acaaaaagtt gtcgttgcaa aaccaggagc tatgatgcca
    49021 gatggaatga tgatctggcc aggaactttg cgaggggtag atagctatgg aatgatctgt
    49081 tccgctcgtg aattgcattt gccaaatgct ccagcaaaaa aaggaatctt agtattgcct
    49141 gaggatgccg tagtcggaga agcatttcca aaataaagag gttgtgacaa gtctttgtca
    49201 caacctcttt tttattaatt ttcactattt tgattttgtt ttaatgccga ttgatcgatc
    49261 gtcaattcaa cagtagttgt tttttctttc gagccttcat agtaagtgat tttgacagaa
    49321 tctcccactt ttttcttata caaagcagat tgaagttcta caccagaaga aacttctttg
    49381 tcatcgatct tagtaatgac gtcgtattgt ttcaatccag ctttttcagc cggtgtagct
    49441 gtttggacat ttgtcacgat gacaccgtta gttacagatg aaggaatctt caagatttgt
    49501 tcttgttgct gagtagaaac ggcagataag tcgaccattg tgatacctag agctggacgt
    49561 gtcacttttc cgtctttttc cagttgattg atgatattca ctacatcgtt acttggaata
    49621 gcaaatccca ttccttctac gcttacatta gaagtagatt cagaagtact tgcgatctta
    49681 cttgagttga taccgataac ttgtccttcg atattaacta aaggaccacc agaatttcca
    49741 gggttgattg ctgcatctgt ttggatcgca ttgatattga ctgtttcgtt cgattcattc
    49801 gtacttgtca cttgtcggtt caaggaagaa atgattcctg aagtgacaga atttgcatat
    49861 tcagatccta gtggggaacc aatcgcaatc gcaggctcac caaccttcag agcacttgag
    49921 tcaccaaaag aggcaactgt ttcgactttg tctgaattga tcttcaacac cgctaaatct
    49981 gaataagcat ctgttccaac taattcagct tttaccttcg taccgtcttt catcaagact
    50041 tcaagacctt gctggccatc tactacgtga ttattcgtga ctacataagc agtattcccg
    50101 tcttttttgt agatcacgcc gcttccttca ctataagctt ccaaattact atcatctgag
    50161 ctgctacttt cttcttgctg cccgaatagt ccgccaaaac cgcttgattg gttttgactt
    50221 tgtaagttga taacagaaac gacagcgtct tgaactttat ctaccgcttt ggtgatatca
    50281 gaatctacat tgactttgac attttccaca actgtttcac cggcagaatt ctgattgccg
    50341 cttgtagcag tagaactatt gttgccagtg cccatcgctg cataaaaaat gccagctgtc
    50401 agtagtcctc caacgatccc tccaacaagc cccagaccca acttacgcca gaggctatta
    50461 tttttatttt ttttcatctt tggtgtcaca ttttttctat ccatgtgttc ctcctccaat
    50521 tacattcatt tatctactgt tagtatagtc ttatttgttg actttagtct actttgagac
    50581 tttgaacttt ttatgaaaaa ctttaggaaa aatcattgtt ttcagatgaa aatatttgat
    50641 tttctttttc cacagatatt gtgtaaaact acgcggatag gattggaaaa ataagggata
    50701 aaacatatcc acagcctgtg tataaagtgg ataaattctt ataaaacgta tgtttgccta
    50761 atgaatgtga tgaaataagg taaaacaacg ctgttttctg tggataaacc tgtggatgtt
    50821 gtgcataact gttggggaaa tctttttaac aaaaatagtc aaaataaaca tatagacgaa
    50881 aaaattgatt ataataaaca aagtgagcgt gaagatcaaa ggagagaaaa catgaatatc
    50941 aaaattattt cagtaggaaa attaaaagaa aaatacttga tccaaggtat caatgagtat
    51001 gtcaaacggc tgaatgccta tgcgaaaatc gaattgatcg aagttcctga cgaaaaagcc
    51061 ccggagaatt taagcgaagc gcaaatgaga caagtaaaag aaaaagaagg agaacggatc
    51121 ttagcgaaaa tcaaagaaca agaatacgtc tatggcttag caattgaagg gaaaaatccc
    51181 acaagcgaat cttttgctaa acaaatcgac caattaggta tccaaggaaa aagccacctt
    51241 gtttttgtta tcggcggttc tttaggactc agcgaagccg tcatgaaaag aagcaatgct
    51301 cagatctctt ttggcaaaat gacgtatcca catcaattga tgcgcctgat cctcgtcgag
    51361 caaatctacc gtgccttccg gatcaacgcg ggggctccat accacaaata atgatatttt
    51421 ttaagagaaa aatagcataa aaatctagtt atccgcataa aaactggact tatcacactt
    51481 tatcaaggtc aaaaccactc aatttactac taatttacta cttatgaatg agctttgata
    51541 cgacgattta tccttgaaaa gtgaagatat aaagatactt ccaataaaat ttgaatattt
    51601 aataggtaga cacttcaaaa aatgaggtgt ctattttttt acccgatttt gaaaggaagt
    51661 gaacttatga aaacaaaaaa tcaagaatca aaaggtcgtt ccccactctt taagaccatc
    51721 aaacattcat tcagccaata aaaaagaaag gataggtaaa aatatggaac ttaaatttgt
    51781 gattcccaac atggaaaaaa cattcggcaa tttagaattt gctggcgagg ataaagtcgt
    51841 tcagcgaaga atcaacggac ggctaactgt cttatcaaga agctataatc tctattctga
    51901 tgttcaaaga gcagatgata ttgtggtggt gcttcctgct gaagctggcg aaaaacattt
    51961 cggctttgag gaacgtgtga agttagtcaa tccacgtatt accgcagagg gctacaaaat
    52021 cggcactcgt ggttttacaa attacctttt acatgctgac gacatgataa aagaataaag
    52081 aaagagagga aaaatgatga gattagcaaa tggcattgta ttagataaag acacgacttt
    52141 tggagaattg aaattctctg ctctacgtcg tgaagtgaga atccaaaatg aagacgggtc
    52201 ggtttcagat gaaatcaagg aacgtaccta tgacttaaaa tccaaaggac aaggacgcat
    52261 gattcaagta agtattcctg ccagcgtgcc tttgaaagag tttgattata acgcacgggt
    52321 ggaacttatc aatcccattg cggacaccgt tgctactgcc acctatcaag gagcagatgt
    52381 tgactggtat atcaaggcag acgatattgt gctgacaaag gattctagtt cattcaaagc
    52441 tcaaccacaa gcaaagaaag aaccgacaca agacaaatag tcgctaggta gaaaggagac
    52501 tttttcgcat gaaacagcgt ggtaaaagga ttcgcccatc tggtaaagat ttagtctttc
    52561 attttacgat agcgtcactc ctgcctgttt tcctgctggt tgtcggactg tttcatgtga
    52621 agacaatcca gcagatcaac tggcaggatt ttaacctatc acaagcagat aagattgaca
    52681 ttccctattt aattatcagt ttcagtgtcg caattcttat ctgcttgctg gtagcgtttg
    52741 tattcaaacg ggttcgctat gatacggtta aacaacttta ccaccgtcaa aaactggcaa
    52801 agatgatact tgaaaacaag tggtatgaat ctgaacaggt caaaacagag ggtttcttta
    52861 aagatagtgc tggtcgtaca aaggaaaaga taacctactt ccctaaaatg tattatcgac
    52921 ttaaaaatgg cttgatacag atacgggtgg aaatcacgct gggaaaatat caagaccaac
    52981 tcttacactt ggaaaagaaa ttagagagtg gcttgtactg tgagctgacg gataaagagt
    53041 taaaggattc ctatgtggaa tatactttgc tctatgacac catagccagt cgtatttcta
    53101 ttgatgaagt agaagctaaa gatggtaaac ttcgcttaat gaaaaacgta tggtgggaat
    53161 atgataagct ccctcatatg ttgattgctg gtggtacagg tggcggtaaa acttacttta
    53221 tactgacact gattgaagcc ttgcttcata cagattcaaa actgtatatt cttgacccga
    53281 aaaatgctga tcttgcggac ttaggttctg tgatggcaaa tgtctactat agaaaagaag
    53341 acttgctttc ttgcattgaa acattctatg aagaaatgat gaaacgtagt gaggaaatga
    53401 agcagatgaa gaactataag actggcaaaa attatgctta cttaggtctc ccggcacact
    53461 tcttaatctt tgatgaatac gtcgctttca tggaaatgct gggaacaaaa gaaaacaccg
    53521 cagttatgaa taagctgaaa cagattgtca tgttaggtcg tcaagctggc ttctttctaa
    53581 tactggcttg tcaacgtcca gacgcaaaat atttaggcga cggaatccgt gatcagttta
    53641 atttcagagt ggctttaggt cgtatgtctg aaatgggcta tggcatgatg tttggcagtg
    53701 acgtacaaaa ggatttcttc ttaaagcgaa tcaaaggtcg tggctatgtt gatgtaggaa
    53761 caagtgtcat atcagagttt tatactcccc ttgtaccaaa aggatatgat ttcttggagg
    53821 aaattaaaaa gttatccaac agcagacagt ccacgcaggc gacgtgcgaa gcggaagtcg
    53881 caggtgtgga ctgatcttgc tggctggtgt ggcaatagcc acgccagcac ttaacccctc
    53941 ggtatctaac aggggggtac aaatcgacag gaaacagtca aaaaaacatt agaaaatcct
    54001 ttggttacaa gggatttaca aaatttcagc gtatgtcaaa tgggctttaa aagttgacat
    54061 acgccttttt gattggaggg atttttactg aatgaacaaa cttggttaca gcatttaaaa
    54121 gaaaaacgct tggcttatgg actatctcaa aaccgtttag ctgttgcgac tggtattaca
    54181 aggcagtatc taagcgatat tgaaacagga aaagtcaagc catcagagga tttacagcag
    54241 tccctttggg aagctctgga acgcttcaat cccgacgctc cccttgaaat gctgtttgat
    54301 tatgtaagaa ttcgctttcc gacaacagac gtacagcagg tggtcgaaaa catcttacaa
    54361 ctgaaactgt cctattttct tcatgaggac tatggtttct attcttattc agagcattat
    54421 gctttaggcg acatattcgt cctttgctcc catgaactgg acaaaggagt tctggtggaa
    54481 ttgaaaggtc gtgggtgcag acaatttgaa agctatcttc tggcacaaca aagaagctgg
    54541 tatgagttct ttatggacgt tttggtggct ggcggtgtga tgaaacgcct tgaccttgcc
    54601 attaacgata agacagggat tttaaatatc cctgtactca ctgaaaagtg ccaacaggaa
    54661 gaatgtatct ccgtcttccg cagttttaaa agctatcgca gtggcgaact ggtacgcaaa
    54721 gaggaaaagg aatgtatggg aaacaccctc tatatcggtt cattacaaag tgaagtttat
    54781 ttctgtatct atgaaaagga ctacgagcag tacaagaaaa atgatattcc cattgaagac
    54841 gcagaagtaa aaaaccgttt tgagattcga ttgaaaaatg agcgtgccta ttatgcagtc
    54901 cgtgatttac tcgtctatga caatccagag cataccgcct ttaaaattat caatcggtat
    54961 atccgttttg tagataaaga cgattccaaa cctcgttctg attggaaact gaatgaagaa
    55021 tgggcttggt ttattgggaa caatcgtgaa cgattaaaac taaccacaaa accagagcct
    55081 tactccttcc aaaggacgct gaactggcta tctcatcaag ttgccccgac cttaaaggtt
    55141 gcgattaaac ttgatgaaat caaccagacg caggttgtaa aagacattct cgaccatgcg
    55201 aaactgacag accgacacaa gcagattttg aagcaacagt cagtaaaaga acaggacgtg
    55261 ataacaacaa aaaaataact caaatacaaa ttcattgaat atagagagga gaacattttt
    55321 atgaattttg gacaaaacct
//
LOCUS       DAZULR010000016        54906 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.016, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000016 DAZULR010000000
VERSION     DAZULR010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 54906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54906
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.016"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            208..1014
                     /gene="proB"
                     /locus_tag="ACG8ZV_001076"
     CDS             208..1014
                     /gene="proB"
                     /locus_tag="ACG8ZV_001076"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HFS4996431.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            1011..2258
                     /locus_tag="ACG8ZV_001077"
     CDS             1011..2258
                     /locus_tag="ACG8ZV_001077"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HFS4996432.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVIGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            2334..2678
                     /locus_tag="ACG8ZV_001078"
     CDS             2334..2678
                     /locus_tag="ACG8ZV_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996433.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(2795..3121)
                     /locus_tag="ACG8ZV_001079"
     CDS             complement(2795..3121)
                     /locus_tag="ACG8ZV_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996434.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(3736..4938)
                     /locus_tag="ACG8ZV_001080"
     CDS             complement(3736..4938)
                     /locus_tag="ACG8ZV_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4996435.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            5055..5570
                     /locus_tag="ACG8ZV_001081"
     CDS             5055..5570
                     /locus_tag="ACG8ZV_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFS4996436.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(5769..6215)
                     /locus_tag="ACG8ZV_001082"
     CDS             complement(5769..6215)
                     /locus_tag="ACG8ZV_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HFS4996437.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(6262..7740)
                     /gene="msr(C)"
                     /locus_tag="ACG8ZV_001083"
     CDS             complement(6262..7740)
                     /gene="msr(C)"
                     /locus_tag="ACG8ZV_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HFS4996438.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(8094..8723)
                     /locus_tag="ACG8ZV_001084"
     CDS             complement(8094..8723)
                     /locus_tag="ACG8ZV_001084"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFS4996439.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            complement(8707..9171)
                     /locus_tag="ACG8ZV_001085"
     CDS             complement(8707..9171)
                     /locus_tag="ACG8ZV_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFS4996440.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(9658..10926)
                     /locus_tag="ACG8ZV_001086"
     CDS             complement(9658..10926)
                     /locus_tag="ACG8ZV_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFS4996441.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(11157..11894)
                     /locus_tag="ACG8ZV_001087"
     CDS             complement(11157..11894)
                     /locus_tag="ACG8ZV_001087"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFS4996442.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(11961..12530)
                     /locus_tag="ACG8ZV_001088"
     CDS             complement(11961..12530)
                     /locus_tag="ACG8ZV_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DapH/DapD/GlmU-related protein"
                     /protein_id="HFS4996443.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            12658..13530
                     /locus_tag="ACG8ZV_001089"
     CDS             12658..13530
                     /locus_tag="ACG8ZV_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFS4996444.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            13872..14744
                     /locus_tag="ACG8ZV_001090"
     CDS             13872..14744
                     /locus_tag="ACG8ZV_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFS4996445.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            14741..16699
                     /gene="nagE"
                     /locus_tag="ACG8ZV_001091"
     CDS             14741..16699
                     /gene="nagE"
                     /locus_tag="ACG8ZV_001091"
                     /EC_number="2.7.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015572 - N-acetylglucosamine
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-specific PTS transporter
                     subunit IIBC"
                     /protein_id="HFS4996446.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(17031..17882)
                     /locus_tag="ACG8ZV_001092"
     CDS             complement(17031..17882)
                     /locus_tag="ACG8ZV_001092"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFS4996447.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKKLEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            18005..18472
                     /locus_tag="ACG8ZV_001093"
     CDS             18005..18472
                     /locus_tag="ACG8ZV_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HFS4996448.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(18735..19217)
                     /locus_tag="ACG8ZV_001094"
     CDS             complement(18735..19217)
                     /locus_tag="ACG8ZV_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFS4996449.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVIA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(19317..20180)
                     /locus_tag="ACG8ZV_001095"
     CDS             complement(19317..20180)
                     /locus_tag="ACG8ZV_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFS4996450.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGARLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYELVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            20778..21653
                     /locus_tag="ACG8ZV_001096"
     CDS             20778..21653
                     /locus_tag="ACG8ZV_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SWIM zinc finger family protein"
                     /protein_id="HFS4996451.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPQFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKTKETVKKDDFNEK"
     gene            complement(21798..21950)
                     /locus_tag="ACG8ZV_001097"
                     /pseudo
     CDS             complement(21798..21950)
                     /locus_tag="ACG8ZV_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
     gene            complement(22218..23549)
                     /locus_tag="ACG8ZV_001098"
     CDS             complement(22218..23549)
                     /locus_tag="ACG8ZV_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFS4996452.1"
                     /translation="MGKSSRKDIVFEKFGIVATKLGNQIHLRTLRDAFATFMPFMMLA
                     GFVTLINSVILEPTGFMGEIVDTSTLTTLQQIGTSIANGTLSITTLLVVAAVSYHMCA
                     SRNYTNHIAAVLVAISTFVVLTPMQMMFTPENADKAVEVTGVIPISYTGASGMFVGIF
                     VGLAATELFIKLSNNKKLQIQLSGNIPPAVLKSFNVLIPIIITITSFALLSFIIIQLF
                     NMDINKLITTIVTEPLSKITTGLPGFLLITSIANLFFGFGIHQAVISGSLLDPFLIQN
                     MQENMAAYANKEQIPHIINMAFKDTFAVMGGSGNTIALLIAIFIFSRRKDYKDFAKLS
                     VTPAIFNISEPIIFGLPIVFNISLIIPFVLAPIFSLTVAYFATAVGLINHVVVQIPWT
                     TPPVISGFLATAGDWRAAVLQILIIAASVFIYLPFLRIDEHVTTKLSENET"
     gene            complement(23698..24411)
                     /locus_tag="ACG8ZV_001099"
     CDS             complement(23698..24411)
                     /locus_tag="ACG8ZV_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016611336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFS4996453.1"
                     /translation="MKKIAKYMEIYLDIKKKIVNGEYKIGEKLPTGDELAVIYHTSKL
                     TVKKGVDLLVSEGVLRSRSGYGTEVVRTPIDNSRVLGPNEGLFSVVGEEHVDSEIHTF
                     SIELPSKKVADKLSISVKDYVYNIVRSRFIDCQPYSIEQTFMPLAVIPGLEPKHLKKS
                     VYAYITNELGLEIKTSHIRIKGDTANEFDAKILKIDPGEFMIEIDKVVALSSGKPFEY
                     SVSRHLYQDFVFEAVFVEK"
     gene            24586..26010
                     /locus_tag="ACG8ZV_001100"
     CDS             24586..26010
                     /locus_tag="ACG8ZV_001100"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFS4996454.1"
                     /translation="MTTMKKLTFPDDFWWGSAWSAEQAEGKGETGKAETIWDRWFKEQ
                     PYRFYQRIDSSITTDHIHQYKEDIELMKKTGHNSFRVSISWARMFPNGGTGKVNPKAI
                     SFYRKLFSEMNNNGIKVFANLYHFDMPATLQDKGGWESREVVDAYVHYAETCFKEFGD
                     LVCHWFTFNEPLGPILGTYLEDFHYPNLIDFKRGAQAAFFTILAHAKAIQVFKELALP
                     SKIGVILNLSPTFPRSQNPADVKAAEIADLFYTRSFLDPMVKGNFSKKLILLLQEYNQ
                     LPEDYTKEDLVCIYENTAQILGLNYYEPRRVKSRSSMVDTSSPFLPEWFFEPHIMPGR
                     RMNEYRGWEIYEKGIYDLCMDIKNHYGNIEAFISENGMGVADEERFMDDTGQIIDDYR
                     IEYIKDHLAYLWKAINEGCNIKGYHLWTFIDCWSWINAYKNRYGLVSLDLTTQKRTIK
                     KSGEFYKQLSDTNGFRYDVDLLVE"
     gene            26309..27016
                     /locus_tag="ACG8ZV_001101"
     CDS             26309..27016
                     /locus_tag="ACG8ZV_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HFS4996455.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLIYAGSAQFITVSMLASHSPLLSIVLSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVILV
                     VTLIGCGLGVWIKHAFF"
     gene            27003..27326
                     /locus_tag="ACG8ZV_001102"
     CDS             27003..27326
                     /locus_tag="ACG8ZV_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HFS4996456.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRILPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLVGILSLS
                     LIRLL"
     gene            complement(27415..28452)
                     /locus_tag="ACG8ZV_001103"
     CDS             complement(27415..28452)
                     /locus_tag="ACG8ZV_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HFS4996457.1"
                     /translation="MSEKELMKVVGFYEGLSIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGAGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHIL
                     GKVVVSGPFNG"
     gene            complement(28773..29756)
                     /locus_tag="ACG8ZV_001104"
     CDS             complement(28773..29756)
                     /locus_tag="ACG8ZV_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase"
                     /protein_id="HFS4996458.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKEPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILDTFEKEHPTLFSEQ"
     gene            complement(30171..30941)
                     /locus_tag="ACG8ZV_001105"
     CDS             complement(30171..30941)
                     /locus_tag="ACG8ZV_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4996459.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMIFGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(30934..31869)
                     /locus_tag="ACG8ZV_001106"
     CDS             complement(30934..31869)
                     /locus_tag="ACG8ZV_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4996460.1"
                     /translation="MANALEINNLKKVYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDTDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYETKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(32185..33834)
                     /locus_tag="ACG8ZV_001107"
     CDS             complement(32185..33834)
                     /locus_tag="ACG8ZV_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HFS4996461.1"
                     /translation="MGQREFIVLIIIAAVILLVALDIFSRLKLKETVRSKWEKIPYQP
                     RFDKEESLKEAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDQQLEKLIAFYQENPQLREKIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGLGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKLPTPLQEELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAILNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLDYPETLVETAKTEAALFDEKRQWHVLG"
     gene            complement(33951..36554)
                     /locus_tag="ACG8ZV_001108"
     CDS             complement(33951..36554)
                     /locus_tag="ACG8ZV_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HFS4996462.1"
                     /translation="MVNAHIIQHTHWDREWYFTNEDAIVLSDQVFTEVLDELERNPKV
                     NFCLDGQTSIVDEYLEINPQKLKVIQRLMKTGQLFVGPWYAQTDALLVDAESILRNLM
                     IGISDTILKYGDPMMVGYLPDTFGFNANLPTLLHQVEIDNFMCWRGLNFETMVPSPYF
                     IWKGLGDKFVYAMNFPFGYMTGMMTLDAIKDIPEFAKEKLDEAVEMLHMQGKNKDILV
                     PSGVDQKSMILNFDQVVEKLNKYSKFHNIISDYPSYVEVIRNKKELPEYKGELRQPVY
                     SRVHRSIGSVRTKMKIENFKLEQKILKRVEPLMLIAERNGIHISKGLLRRLWKKILQN
                     QAHDSIGGCVSDNVAEDIFHRIKEANEIADGIENLIVKRMADALKLKSNEVLVFNTTT
                     ENYSGSKIVHVVADSKKIHFKGSPYNIIEKEVYFPERKNAYRMIATGFEYFDEPAYYE
                     LDIKINVNVPALGYTVVEFEKNNEKLETAIEIDKTEISNNKYKLSFKDGQLNLIVGDR
                     QYLDFVHLIDSANDGDTYDYSPLEGDTELSLKLETAKVYKDSLQETLVVYGKAQLPKD
                     LKDRLSEKPEMEEISYEISFSLGESQIVEGTLKIHNTVYSHRMRLAINVLDKSEKSIA
                     QIQNGFIENTPDVIPPNWSETMVEKPVNLEIFDKSVSVAENDHYFTFYADGLKEYERI
                     ENQLIITLFSTTGELGKPNLAWRPGRASGDTTNEGHVMMETPLAQEIGEYKVTFGFNV
                     EEGRFNEFKVAKQAEKRLEQSISYQKQKLNVFIHRLDNKIWPLQNELDVPRKFSLIEL
                     PEDLIVSSIYPSYFHEQGFVLRLANPTEQEKIVPEAILSLGTVVNALENKQELTTIPP
                     YDYLSILINER"
     gene            complement(36566..37615)
                     /locus_tag="ACG8ZV_001109"
     CDS             complement(36566..37615)
                     /locus_tag="ACG8ZV_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HFS4996463.1"
                     /translation="MEFKKQGREILNHFQSGVSYMIPLVVAAGLLTSIAVIFGGTGVW
                     DQTDTFWGVLRMIGQTGLQFIVPMISAYIAYSIADRPGLAPAFITGMMCQNLGMGFIG
                     GMVAGLACGYLANALKKVKVPMQVISLKSIMLIPFVTTLVVGIILWYVLATPIQAMTT
                     GLTNWLEGMSGANAALMSAILGGMMAFDMGGPINKIAYAFGVASFSSGSFGPSTAMLL
                     GIAIPPFGMFLATILNKKLYDESERDNAKTAMIMGLVGITEGTIPFAVKDPLRVIPSI
                     VVGTAVACGLNGFFGVTQETMLSTFMAIPFVTNIPLYLVSIVIGGVVTALMVNALKSI
                     KYKKEQQVNSVEEGK"
     gene            complement(37641..37955)
                     /locus_tag="ACG8ZV_001110"
     CDS             complement(37641..37955)
                     /locus_tag="ACG8ZV_001110"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_function: GO:0090563 - protein-phosphocysteine-sugar
                     phosphotransferase activity [Evidence IEA];
                     GO_function: GO:0090582 -
                     protein-phosphocysteine-D-fructose-phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HFS4996464.1"
                     /translation="MTKIVAVTACIAGIAHTYMAKANLEKFAKKKGLDIKVETQGAMG
                     IENKLSISDVSEADVVIFAVDTNVSERGRFDGKPILTVGTSEVVKDGEETIDEAIALI
                     NK"
     gene            complement(37971..38417)
                     /locus_tag="ACG8ZV_001111"
     CDS             complement(37971..38417)
                     /locus_tag="ACG8ZV_001111"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose PTS transporter subunit IIA"
                     /protein_id="HFS4996465.1"
                     /translation="MISEKININNIVIDLNASDKKSVVEKLSKLLETNGFVSDHKQFQ
                     KDVFDRENHMTTGIGKNIAIPHGKSLAVIESTVAVAKLKRSVEWGALDDQPVDLVFLL
                     AIKDTDKGTNHLRILAELSGRLMDDEFVKRIKDSRNKKELVKALSF"
     gene            complement(38418..40340)
                     /locus_tag="ACG8ZV_001112"
     CDS             complement(38418..40340)
                     /locus_tag="ACG8ZV_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFS4996466.1"
                     /translation="MGIEFSERQMKILYFLIENEHTTYKELSEQLYVSTKTISKDILI
                     LKEIIQKMPDVQMLVQPKKGVSLIGKKETLRNLLSSHKINIADSPEDRLTYVFAKLLN
                     TNDSLKIQNLADELYVSRSTVESTMKDVRKRLNKHGMSLVSDRNGVRIKADEKSKRRL
                     MSEVVNYYWGGFTASNSKTDLLDLNINFIGEANNFLNKDILKKVAELLNRYMNKTQLK
                     FTDYEFQTLAIHLAIAIERIETSNFLSRSNNSEEEISKNTLILIKMIEKAFSIIVPID
                     EQAYVDIHITSIEKNAMNHDLDQTKLSYLDMGVELQELVRIKLNEFYPDEELINNLVL
                     HLNAAVKRLKLGVNIYNPYTDKIKYSFKRSFMISVDLLEEIEERFCIHFNEDEIAYVT
                     LHIQSLLDRYKPDKTKVILVCSSGYGTSKLLEQRINNGFADMVEIEDVLSINELQDRK
                     VTDELVISTIPIENTNFPVIVVSPLMLGADVRKVKQYLQLNEQTEDAFLNLLDKRFCF
                     FTHQIKDNQVNVLNIITKKLVKENYAKEGILEGAIKREKLSSTAMNDFAMPHIEVDFI
                     KKPVICVYVNPEGIDWDGTLVHSVFFFALNEKVKPELNKIYETFNEIASNHELLANLK
                     TSSSFEKLVYILKEGL"
     gene            complement(40552..41448)
                     /locus_tag="ACG8ZV_001113"
     CDS             complement(40552..41448)
                     /locus_tag="ACG8ZV_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFS4996467.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWLDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDPFIRLTVANPIKPGTQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(41441..42121)
                     /locus_tag="ACG8ZV_001114"
     CDS             complement(41441..42121)
                     /locus_tag="ACG8ZV_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFS4996468.1"
                     /translation="MVLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(42122..42904)
                     /locus_tag="ACG8ZV_001115"
     CDS             complement(42122..42904)
                     /locus_tag="ACG8ZV_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFS4996469.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMLAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LTLGTLSVPVALTFITRSTSVSLLLSFLYIMGTAFIPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(42897..43814)
                     /locus_tag="ACG8ZV_001116"
     CDS             complement(42897..43814)
                     /locus_tag="ACG8ZV_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFS4996470.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(43978..44232)
                     /locus_tag="ACG8ZV_001117"
     CDS             complement(43978..44232)
                     /locus_tag="ACG8ZV_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996471.1"
                     /translation="MSTITTITMVASPLGLALFGALFDWKTTQPRLRDSLIFLGGSLA
                     IVILITGLVKLLKLDLKEAKIFSEEEYRETTLVEKKESGN"
     gene            45089..48316
                     /gene="fss3"
                     /locus_tag="ACG8ZV_001118"
     CDS             45089..48316
                     /gene="fss3"
                     /locus_tag="ACG8ZV_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HFS4996472.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVAPVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYCQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            48429..48743
                     /locus_tag="ACG8ZV_001119"
     CDS             48429..48743
                     /locus_tag="ACG8ZV_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFS4996473.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            48756..49130
                     /locus_tag="ACG8ZV_001120"
     CDS             48756..49130
                     /locus_tag="ACG8ZV_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFS4996474.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            49140..49475
                     /locus_tag="ACG8ZV_001121"
     CDS             49140..49475
                     /locus_tag="ACG8ZV_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HFS4996475.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            49558..50898
                     /locus_tag="ACG8ZV_001122"
     CDS             49558..50898
                     /locus_tag="ACG8ZV_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HFS4996476.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKICYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            50976..51650
                     /locus_tag="ACG8ZV_001123"
     CDS             50976..51650
                     /locus_tag="ACG8ZV_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HFS4996477.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            51643..51807
                     /locus_tag="ACG8ZV_001124"
     CDS             51643..51807
                     /locus_tag="ACG8ZV_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996478.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            51883..53025
                     /gene="dcm"
                     /locus_tag="ACG8ZV_001125"
                     /pseudo
     CDS             51883..53025
                     /gene="dcm"
                     /locus_tag="ACG8ZV_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            53015..53305
                     /locus_tag="ACG8ZV_001126"
     CDS             53015..53305
                     /locus_tag="ACG8ZV_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996479.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            53564..54748
                     /gene="mobT"
                     /locus_tag="ACG8ZV_001127"
     CDS             53564..54748
                     /gene="mobT"
                     /locus_tag="ACG8ZV_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobT family relaxase"
                     /protein_id="HFS4996480.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            54745..54882
                     /locus_tag="ACG8ZV_001128"
     CDS             54745..54882
                     /locus_tag="ACG8ZV_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HFS4996481.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
BASE COUNT        16891 a        10837 c         9976 g        17202 t
ORIGIN      
        1 tactcctatt ctaacatatc cgaggctgta aaagactttc tttacaaatt cttcaagaaa
       61 ttctgctatc ttaaagtaaa ccattaattc gttctttttc caaacgactg caagttgtac
      121 aaaaaaacta ttttttacat gactttactc gtcaaaacaa gtagaataga acgaaattaa
      181 tgagtggata tttgattgag gtgtcacatg cgtaaagaaa ttaaaaatgc aaaacgaatt
      241 attgtcaaag taggaacaag tacattgatt tatcccaatg gaaatatcaa tcttgcggca
      301 atcgatcagt tagcttttgt cctttctgat cttagaaatc ggggaaagga agtgatctta
      361 gtctcatcag gagctgtagg cgttggtatg cataaattac atttgtcaga acgtccgact
      421 ttgattcctg aacagcaagc tgcggcggct gttggtcaag ccgaactgat gaatatctat
      481 aatcaaagat tcagtgtata taatcaacag acggcacaga tcctcgtgac aagagacgtg
      541 gtagattatc ctgaaagtcg taaaaatgtg aggaatacat tggaacagct tttgattatg
      601 gacacgatcc ctatcgtgaa cgaaaacgat actgtagcag tggatgaatt agatcatctg
      661 acaaaatttg gcgataatga tcagctgtca gccatcatgg caaaacttgt cgcggcagac
      721 cttttgatcg tcctttctga tatcgacggg ttttattcag ataatccgac tacaaatccc
      781 gaggctcaga tgtatcgcta tatcgataaa atcgatgaaa agattctggc acaagcaggt
      841 ggtgctggta gcacatttgg aacaggcggt atgcagagta aattaaaagc cgcttctagg
      901 atatttgaag caaacagcgc aatgatttta gcaaatggaa aaaatccggc aattattttt
      961 gatattcttg caggaaaaga agtaggtact ttatttaagg aggacttgaa atgactgact
     1021 tgatgcaatt aggacaacag gcaaaagata gcgcgcaaca actagcactt atgcctacaa
     1081 accgcaaaaa tgagctactt gttcaaatgg cacaaaccat caaaaagaat caacaagcga
     1141 tcattgaagc aaatcataaa gacttagaaa aagcagtcga aaacaatatc agtgaaacga
     1201 tgcaagaccg cttgcagctg acacctgagc gaatcaatgc catggctaca gagatcgaaa
     1261 aaattgcttc gttagacgat cctattggaa aagtagatga gatgtggacg aacaccgacg
     1321 gattgagaat cggcaaaaag cgcgtgccac taggcgtgat cggcatcatt tacgaatctc
     1381 gtccaaatgt cacgacagat gcagctagtc tagcattcaa atcagggaat gccgttatcc
     1441 ttcgcggtgg caaagaagca ttcttctcga atcaattatt agtccaatta ttgcagcaag
     1501 tactggtcag tgctggcgaa tctccttatg ccatccagtt tgtcgatgat acttctcatg
     1561 aaactgcagg acagttgatg cgattgacag aatacttaga tgtgctgatt cctcgaggcg
     1621 gagcaaaatt aatccaacga gtcaaagaac aggcaacggt acctatcatt gaaacaggta
     1681 caggaaataa tcacgtatat atcgataaag aagcacagtt atctatggca gtgaacatca
     1741 tcgtcaatgc aaaagcttcc cgtccatctg tctgtaacgc ggcagaaaca ttgctgatcc
     1801 attctgagat cgcacctttt ttcttgccag ctattgaaaa agaactggta gaacacgggg
     1861 tctctttacg tgcggatgct cgtgcgttag aatatctaga gacggctgct ttagcagaag
     1921 acacagattg ggatactgaa tatctagatt atatccttgc tgtcaaagtg gtcgattctt
     1981 tggatgaagc aattgcacat atcaatcggc ataatactaa acattcagaa acgatcgtga
     2041 cagatagtta tgcggctagt caacgtttct taaatgaagt ggacgcggcg gctgtctatg
     2101 tcaatgcctc cactcgtttt acagacggat cggtatttgg ttttggtgca gagattggta
     2161 tctctactca aaagttgcat gcccgtggtc caatggggtt aaatgaatta acttccacaa
     2221 aatatatcat ttatggcgat ggacaaatcc gcgaataatg tttcgtgtga aacattattc
     2281 ccgccttttg ccttttttct gtaaaggttc tatccaacta gaaaggtgtc aatatgtttg
     2341 aaattttaat gatttttttt atttacctta tttctctgaa tatcgctgct tttctgggag
     2401 tcggtatttt atcccttttc tttcaattca aaaaacgaag catagggagt caacgggaaa
     2461 aatggtcgca gtattttgac aaaatcgggc aaaaagggct ggttacacgc ttgcacatta
     2521 gttacatggt tgcattatgc ttattagcga caatcaatta ctattctttt ttcgatcatt
     2581 caatcgctta tacgattacg ctactgattg ctgggatttt tcacttatct tataaatatc
     2641 agctgaataa aaaccacttg aatcggactt tccgctaaaa aatatccgta cgataagtag
     2701 agtgccttga agatcggcaa aaaactgccg gactttttag aggctgtgac aaagattttg
     2761 tcacagcctc tttttccata taaacggcgt tcgcctacca gctgcctggt aaatctgttt
     2821 cctcttcgtt aagaagcgaa aatccgtcaa atgtttcgcc atcataataa cgaagcagct
     2881 catccatgga caagttcatc gttttttctt tttcttcttc cgctgattca gccagtagct
     2941 gttcccgata cacctgatac ataccagcta ttttttgctg catcgctttt ctagtttcac
     3001 cttccgcatt gattattggc aattctttga tatagccacg ataaatcaac cgatcatctg
     3061 aaaattcaat gggtaattca acgagtgtca acccgacttc ctgaaaatat tcttccagca
     3121 tctattatcc ccccattctt tttcttaaat gaattttagc ttacctactg aaaattttcc
     3181 agtttcatta ttttgagaaa aaaagggaat gtgacaaaaa tcgtgtcaca tccccttttt
     3241 ccgaataaat ggtgttcttc tgccaactcc tcaatcataa gtcacaatat tcaacaaaca
     3301 tgagaaactg ttttttgaaa ttgttccttg tgattcagag ttaaacgaca gtctcacaac
     3361 ctcttggtaa acggcgttca atcagctgac cctcggtatt agctcaaaaa acggtaaaat
     3421 atgagaagct atttttccgt tttgtttctc taatacttag gataaaacgc tgattttaca
     3481 acctctgtta aacggtgttc aatcagctgt ccttcggtat tagctcaaaa aacggcaaaa
     3541 tatgaggaac tatttttccg tttgtttctc taatactcag gacaaaacgc tgattttaca
     3601 acctcctgat aaacggtgtt caaaagcttg catctgcggt aataagccca accaaacgaa
     3661 aaatatgaga agctattttt gtttggctgt tcttatgact tgatgcagga cagctttttc
     3721 acaacctctg atttcttatt cttcttcatt tgtagcaaaa taattacggt gataaatgat
     3781 acaacataca ctgataagaa caatggcacc tgcaaaataa aacgcatagc tttcaccaat
     3841 atgttcacca atcacacctg caataaatgg tgctaaagct ccaccgaaaa agcggacaaa
     3901 actatagctg gacgaagcaa cgtttcgttg cagacctggt atttccatag caatcgtcgt
     3961 caacagtgta ttgataattc cttggaaaaa tcctgctaac acaatgctga tcggtacaag
     4021 gactggcata gaagttccag ctcctaataa cagcaaacaa ataatgaata agacaaatgc
     4081 tgctaaaatt gtccgataag tcgtaaactt ccgctcaaga gccggtgcaa cgaaaatcga
     4141 agcaatagcc agaagcacac cccagccaaa aaatacaaaa ccgacttcta attcagaata
     4201 gccaatcaat aaaaatggcg catacgcaag taaagtaaag aatccgaaat tatataacaa
     4261 tgcgattagt ccaactgaac gaagtttatg attgcttaac gctttgacac cttcccaaag
     4321 gcctactttt ctctttggtt tctcagtttc aggtaaaagt accgctaggg ctataaaacc
     4381 gcaaaacatc aaaaatgcta ccccaaaaaa tggataacgc catgaaccac tgcccaagac
     4441 cccaccgact agagggccaa cagccattcc gcagccaagt gctgcttcat acatcatgat
     4501 tgctttttct gtgttaccaa ctaaaatact gacgatcgtt gctaaagcag tagagacaaa
     4561 taaagcattc ccgacacccc agccggcacg taacccaatc agcattccga tattcccaga
     4621 taatccgcca agaccagcga atacaacgat gataaacaat cctgtcatca atgttttttt
     4681 caaaccgatc cgactagata agaaacctgt aaatagcatc accacaccag tgactaacat
     4741 gtaactagta aataacaggg tcgtttcagc tggcgtagcg tttaactgtg cagcaatcgt
     4801 ttttaagatt gggtctacta gacccactcc cataaaagcg atcatacagg tagctgctac
     4861 aactagcgct gaacttttcc cctttgtttc ttcatttgtt tgttcttgta tatctatttg
     4921 attctccaat atttccatcc ctttctctct attagcatca tacatgattt attttacatg
     4981 tcaatatgca catgtaaaac gtggaaactt tactgtgata taataaagaa aataagacga
     5041 gaggtaggat ttttatgaat actttagcct atatattatt atgcgtgctt ttatccaaac
     5101 cacgttctgg gtatgaattg aagcagctga tcacaatttt ttgggaagcc catcacagtc
     5161 agatctatac aacgcttgcc aagttagacc agcagggtta tgtgaccgtt ttggacaaag
     5221 acgagcactc tcaaaaaaag atctaccact tgactgatga aggacgtgct cttgtagagg
     5281 aatggatcaa agaggaaact cccgctccta cgcaaaaaga tgaatttcta gcaaaaatct
     5341 atgctttttc gacgctcgat aaaacaacag ctactggact gctattcact agagaacaac
     5401 agctgaacaa aatcatgcaa aaaaatcaaa aaaaattgaa tgacctctcg ctagacaaga
     5461 aacaagaatt tggacgttat gttgtgatcc agcgcagaat tatgctttgt cagcaggaac
     5521 tccaatggtg tcagcaagta agagaacaaa tgcagcagtt ttttgagtaa gggataaaca
     5581 gaacctttct agaaatatct attgaagagc aaattatctt caataaaaga gcaatacagt
     5641 tggaaaagaa aaagcgatcc gaacgacagg ccaaaaccta tcgttcggat cactattttt
     5701 ctagaactgc attcaagaga ctatgacaaa aagcatgcca aggccttttt tcaaataaca
     5761 gtgttccatc attcattact ttgaattgct tttagcacac ttcttgaaag cgggccaacg
     5821 atgatcaact gcaacggtaa agcggcaatc acattcattt tccaagcatt catataagca
     5881 gagaataatt gatcaggtat tccttgttcc atgatcacac cgaataaaga catacatgtc
     5941 accattccta aaaccatcaa gcatgaaata gttaagatca tttggacctt gctttctgga
     6001 tttactggta gtttaaaggc aatttttttc gccagcacac cgatgatgaa gacatccaaa
     6061 atgaaagcca ccacgaatcc aggcactaga ccaatcaaca aacttgataa atgaagatct
     6121 tgatgcagcc ataaattata cgcgctcatc cccaagacca tcaaaaaaca catcattgtt
     6181 gtaaaaatta ttccttcttt tttatttgta ggcaatctgt accactcctt taaatttgtc
     6241 acgaaaatca tcgtagcaca tttaaaaatt tctcgtaagt acttttttta ttttctgccc
     6301 ttttatttca taaacttcat cagccgtacg ctcgacaaag taagaatcat gagaagtaaa
     6361 caaaatcgtt cccggatata tttgcattag cttctctaaa gcttcgatcg ttgccatatc
     6421 aataaaatta gtcggttcat ctaacagcaa cacattactt ggcttagtaa aaagcaaagc
     6481 aatcgtcaga cgggtcgctt ctcccccact taatgtacat aacggtttcg tcaaagtttc
     6541 ctgagcaaac cctaagtgat tcagcaaact acggacaagc gattctgaaa actctgtttg
     6601 tctcatgaca aaacgaatga tggattcttc agatgtcatt tgataaccct tttgctgata
     6661 tacttgaaag cttactttcg gagagagaag gattccttct ccttgtttgc ggatatgttc
     6721 taataaggtt gtcttacctg aaccattttc accgacaatc gcgatttttt tacctaaaga
     6781 aaactgaaaa tcaccattta ccagtaatgt tctcccactt ctttccaatt ggacattttg
     6841 tcccatgatg ggatagcggc tgtggagttc aagagatttt ggtactggaa aacggatttg
     6901 tttcatctgc tgcggcttgg ttgtttctcc tattttttgg agtcttctct ctaatgtttt
     6961 cgcattcttt tggatggctt tttgtacact gtctttttgt ttagaggaag acaaccgatc
     7021 cagtctgatt tgttgctttt tctttttact ggacactttt tccaactttt ccgcttgttt
     7081 tttcttttct tggatcgatt tttccaatcg ttttttctct ttcatgatcg actctgcttc
     7141 tcgtagctga gtctttttct ccaattcctt ttgagtgaga taggcactat aattccccga
     7201 aaactctcgg atttctccgt cttttacttc ccagattttc gatgctagct catctagaaa
     7261 atagcgatca tgactaacaa aaaccagcgt accataataa taacgaagct cttcaatcag
     7321 tcgatcaata ctttttctat ctagatgggt tgttggctcg tctagaagca tcccttgttc
     7381 ataagaagaa agaagacgta tcaactcgat ctttcgttct tcccctccgc tccatttccg
     7441 ctctgaagtt tcttccagtc ttaactggaa atgactggct aattccaaat ttaggtcctt
     7501 tgcttcagcg agataggtta attgaggcag gtagttgaag gtgatctctg tttggatttt
     7561 cccatgatcg ggaaaaagtt caccggctat tagtttgagc aaagtcgatt taccgacacc
     7621 attttctcct atgatcccta tacgatcttg ctgatagaca cgaagagaat caatagatag
     7681 ttctagctgg ttgccaaagc tgacttgtag atttgttata tttactgcta aattttccat
     7741 atgttttaca ctcctatttc atgtaaaaca acaattatcg atactaaaaa agagcagaaa
     7801 aatctgtttg caaaaaaact gcatcacatc ttttcctact ctgaacgaaa taactatgac
     7861 taaatcacca aatctgtcat agctttcacc tattctactg tcgttcgaaa aaatggacat
     7921 actccatcca tgaaattgtt gtttatacat gtcttttgaa tttatttagt tgttattcaa
     7981 aagttcgaaa cgtaatttca tcgatgcagt catttttccg acctcctttt ttattaggtt
     8041 accacacacg attcaaaaaa agcaatagct actgaatagt aactgaaaac cttttattcg
     8101 aacatagtga tcttttctgg tgctaaacga acagactcgt aaccttcttc taccgctttt
     8161 cctattgata aaataataac tggaacataa cggtctttat ccaaaccaaa tgcctctgcc
     8221 aactgatctg cttcgaatcc accaattgga tttgtttcat agccatgatc acgcgcaact
     8281 aacatgaatt gcatagccgc taagctagaa tcgactttga ctacatcgtt catttcttct
     8341 cttgaaaaac tcttgtaata aggaatgatc gcagctaatt gttgatctct gacttctttt
     8401 ggcatcttcc ctgattcgta agcttggttg tagatttctt cgccatattc gtaacattgc
     8461 atatcgccaa aaatcatgac cattgcagaa gaagtatcat tttgtctcgt attgaaacgg
     8521 atcaaaggac gcaagatttc ttttgcttcc tcgctttcag cgaccacaaa gcgccatggt
     8581 ttcatattga cagaagaagg tgcagtcgtc gcttctttga tcatttccag catttcttcg
     8641 tgtgggattt tgtatgtttc atcatatacg cgaacggatc ttctaccagt cataattgtt
     8701 gaaaaatcat ttttttgttc cattattatt aacctctttc gtttctgttg ttatattgca
     8761 aagttgggta ttcaatttat ctaaaagtgt tagaaattgt ttcatttcta catcgctgaa
     8821 agccggggat agcacggaac ctgtatcttt atggtccatt tcacaatgct tgattttctt
     8881 ctgggctttt tctgttagcg ctacatacac ttcccggttg ttctgaggat ttctctgacg
     8941 cgaaacatag ccatttgctt ccaatacctt cagatgacga gtaactgctc cttgatcaat
     9001 ctgcaacttt tcttgcaaac tgctttgtag caatggattt tcttctttca gtctcatcat
     9061 gatctcgtat ctagtaagac ttataccgat attttcttca aagatctgga cgattttttg
     9121 atcggctaat ttgatttgat ataaaaggtg actaatctct tctaaagaca taatttcctc
     9181 ctttctaata attgactcgt caacgattga cttgtcaata atagaataaa aaaagaaaaa
     9241 agtcaaagaa tcagctgtgt aataaaaaaa acgctctcaa tagaaaagta tagagaaaag
     9301 aaattttttg tagaatgaac ggaaaaaatg ataaagaaag cacaacgcta aaaccaagat
     9361 tattgattct tatcaaacta tagaagatag ctcttctgca gtagataatt ttacaccgcc
     9421 aaaaatttcc gaaatcgcct tttgcaagaa tcccgtcgaa tattagaaat tggatcagta
     9481 tgcttaaaca gtaataaaaa agttatgaca agatgttgtc acaacctttt ttgagtaaac
     9541 ggtgttcaaa aacttgcatc tgcggtaata agttcaacca aacaaaaaac atgaaaatct
     9601 gtttttgttt ggctgttctt actacttgat gcagggcagc tttttcacta cctcttttta
     9661 ataaccataa aatcctattc cttcatatct ccagcccatc ggtgttagcc aatctctttc
     9721 cttagcactc aaggtatagt gatgggtacc agttttttca tttggattaa atagtcgata
     9781 aattggcttg gaaccaccag aataaaaact tagaccttca taacgccaac cgatttttgt
     9841 taaagagttg atctcagatt gtgccattgt gtaatgatgg tctccactgt aaggattgta
     9901 taaacggtag acaggttgtc cgctgtttgg tgcttgccaa gcaatccctt catattccca
     9961 gcctacagtt ggcagataat ttttttctcc ggcattcaat gtatataaat gttctcctgt
    10021 atgacggtta tacagacgat acatcggaga agttgaagtt ggtgctgtat catactgtgt
    10081 cagattatag gtttcgatta cattgttcaa tgtagaacca taattaggcg cagtggcata
    10141 acgacctgtt agccaagccg tagcatcttt gtaagagttc gtattgcttt tccatgcacc
    10201 ggaatagtag taaacgcctg gctgaaaaga agtcgtcttc aataccgtta cgttatcttg
    10261 caatgattct ttgtacgaag gatattttct aaaagcggca ttcaccgtaa tccattgccc
    10321 attcacatat tccgaagtag gcatcgtaac agattggcca ttatagcttc ctttaatccc
    10381 aaatagattg taattagggg cagaagccaa agtactgttc ccccagccac tttcaacgat
    10441 ggcttgagca atcatgactg atgcatataa gtcattggca cttgccaaac tttgtgcagt
    10501 tgaggcaata ctatcaatga acgcttgttg agaattagca gatgagcgag cataaaaagc
    10561 atagccagta tagttttcga attcagacaa atctgcttga tgggtatgtg tcaatgtttg
    10621 cccatctgtc aattggttcg tgatttcttc tgcattctct ggattgttct gagcttctgc
    10681 tgatgtactg tcttcggttt gtgtttgttc tgttgtttca gttgttggtt cttcggttga
    10741 aattgtattt tctgagacag tagctgactg caaagtactt tctgtatcgt tttcaattcc
    10801 tgtttctgaa gaactcgatg tctgagttgc gacagtttct gtcgattctt cagctagcac
    10861 tgttgtgttg gcaactgcta gatttcctaa aagaataacg ctaaataata aattctttgc
    10921 tttcatcttt tttctccttt gaattatgaa acttttccta aataacagtg taactaaaaa
    10981 agtaaaagca agtcaatgtc catatttaaa taacatttgt ttctttttaa taaatttgct
    11041 ttttctgcat aaaaagacgt aaatgaagaa tattcttctc cattcacgcc ttaaattgat
    11101 ggtcgtttga ataactattt aacaagtaat tctctctgga tattatccgt tatggattat
    11161 acttcctgtg tcgtcggacg gataatcatg ttgctgacag acatccggtc tggcgtttct
    11221 atcgcaaatg ctacagcaga agctatatct tcagatgtta atccccattc tttttgcgct
    11281 tcatgaagtt caagagcagc ctttttgtcg ctgatggttt gatataattc agtttgaaca
    11341 gctcctggag agatgatcgt agatttgatg ttattttgcc gttgctcttg acgtaatcct
    11401 tccatgattg cacggacagc aaattttgtt ccgcaataaa cggcggaatc aggataaaca
    11461 acatgtcccg ccacagaatc agttgaaatg atatgcccag atttttgttt ttccatgatt
    11521 ggaagtacgg cggaaattcc atttaacaca cccatgatgt tgatatcaag catattttgc
    11581 cattcatcac ggtgaccttc aactaatgga gcggttggca tgattcctgc attattgtac
    11641 aatacatcga ttcgaccgaa cttttccatc gctaaatcga taactgcttg gacttgtgca
    11701 aaatctctta catctgctgt ttgaatatat agctcagctt ctggtaaaga ttcttttatt
    11761 gcttttaggc gatcttctcg gcgtgcagct ataactagtt tagccccttt ttctgctaat
    11821 agcttcgttg ttgcttcacc gattccgctt gaagcgccca tgatgacaat cactttttct
    11881 gataaatcat tcattctatt ctcctcctgt tttgaaaaat ctcttgctta tactcactat
    11941 ctcttatttc atcttactgt tcaaataatc cgttcgacag gtttgacgat tttggcaggg
    12001 attcctgcaa cgatggtatt gtctgggaca tctttcgtaa cagttgcatt cgctgcaaca
    12061 atggcattct cgccaatcgt tacgcctggc agaatagttg ctcctgctcc gatccaagca
    12121 tttttcttga tgtggattgg ctttactgac aagcctcttc gttcttttgg atcggttaga
    12181 tggttcaccg tgatgaggtt gacacgagga ccaatcaata ctgaatcttc taaacagatg
    12241 ccacctaagt caacgaacat cacttgacga ttgataaaga catttttccc tatactaata
    12301 tgtttgccga aatctgtata aaaaggcagc agaacagtca ccgtatcatc tactttgtca
    12361 ctaatgatat tttctagccg tttgcggata tctgctggtt catggtaccc agtattcagc
    12421 gctgctaaag gctcttcgtt ttccgcttgg atctgatgga tcacttcaaa gagcggatcc
    12481 gttactcgaa tctctttatt gacgatttgt ttttcgatga ggcttgtcat tttgctccct
    12541 ccttttatcc ttactttata acggacggct tatgatgtct aatacttata aaacatactt
    12601 aactattcct tttaactata cttagtggta tgctttttta aaaacaggag ggaaaaaatg
    12661 gatattcgta tactgacgta ttttttagca gtagctagag aaaaaaatat cagccgagca
    12721 gcaaaatctc tgcatatcac gcaacctact ctctcaaaac aactgaaaga tttagaagaa
    12781 gaacttggtg tgacactttt cactcgaggc tcccgagaga tacagttgac ggattctggt
    12841 cgatatcttt attcaaaagg aaaagaaatc ttgtcgttgg tagaaaaaac ggcgaacaat
    12901 ttaacaaatg acgcaatcat ctctggagaa atctacattg gcggaggcga aactaaagca
    12961 atctctttca tttctgatag ccttcattcg ttgatcaagg cgcatcctga tatccagttt
    13021 catttatata gcgggaatgc agatgatatc atagacaaac tggatagcgg attacttgat
    13081 tttggactcg taatcgaacc gacaaacaaa caaaaatacc agtcatttcg actgccagcc
    13141 caagatcgtt ggggactttt gatacatcgg aatcatcctt tagcaaagca aacagtcatc
    13201 catccgcagg aactgaaaac tgttcctttg atcatttccc ggcaaacgtc agtggacagt
    13261 caactagctg aatggctagg tttcagcata gatcagttat cgatcgtcgg aacatataac
    13321 ttattgtaca atgcttcttt gatggtcgat aacgggactt ttggtgcatt agctctagat
    13381 gggatcatca atacttatgg gacggaaaaa gtattcatcc cactcgatcc gccattacaa
    13441 gcttcactga atctcatttg gaaaaaagac cagcctcttt ctcctgctgc tcgtaaattt
    13501 ttagatgtcc taacggagaa atacagttaa gtagagtttt tttccttcgc tttcagcttt
    13561 ttaacaacga ataagttaag caaaagatcc aatgattaaa taacataagt ttcttaattt
    13621 gttccttcct tttatttctg ataattccag taaattacta taattataaa aaaagaattg
    13681 acaaaacata actgtctata taaaattgat tacgttaaca ataattcgtt tcatgtgact
    13741 agatcatact aggcatgaaa aatctctgag gaacatggtt tccctaggag gtttttcgtg
    13801 tctatttttg tttggccgca atcaactggt ctagcaaacg tgaaaaccaa atcttcaaaa
    13861 agggtgcgcg catgaaaatc aaaaagatct ttaatcaaaa tgcagtattg gtagatgacg
    13921 gtggacagga aaaagtagct attggaaaag ggattggatt tgacagaaaa agaaatgatt
    13981 tgatttttga tcgtgatgtc gaacggatat ttgtcatgga accagaaggt caaatcaagt
    14041 tgcaaaattt acttaatcag attgatgaac gctttttatt tgcagcagaa acgatcattg
    14101 atcatgcgga aactgttttg atggaaaagt tgaatgaaca tgtattgatc gctttgaccg
    14161 accacattgc tttttctgcg gagaacatta ataacggtat cgtcatccgc aacaaacttt
    14221 taagagaaat cgaagtgctt tacagtgatg aattcagtat tgctcaatgg gcagtagagt
    14281 atctgacaaa agagcttggg attccatata cttatgacga agcaggatat atcgcaatcc
    14341 atattcacag cggacgaagc ggtcggaaca ataaccatcg cagtatccgt gaagtgacga
    14401 ttgtatctga catcatccat ttagtggaat cagaattgga aacagatatc cattcagaac
    14461 cattttcact gaattattca agactggtga atcatttacg actgcttcta caacgaaccc
    14521 atgcgcaaca atatgctgtt ttagacacgg aaatcgtaga aatggtcaaa cgaaaatacc
    14581 cagaaagcta taagatttct aaaaaaatcc gtgtgttgct gaccaaagaa taccagctcg
    14641 cgatcacgaa agaagaactg ggttacttgg ccatccatat cgagcgttta agaagcgcaa
    14701 tcgtacaaac aaatgttaac aatcatgagg aggaaaaaaa ttgaaagcat atctacaacg
    14761 aatgggacgt tcccttcaac ttccagttgc ggtcttacct gctgctgctt tactagtagg
    14821 gatcggaaac tggtgggcat cttatagtaa cgacattgtc gctcattttt tacaagctgg
    14881 cggtaacgca gttttaggtc aattaccttt gctgtttgcc gttgggttag cactagggat
    14941 gtcagtggac aaatcaggtg ctgctgcctt ggcaggtttg gtcgcatttg aagttccagt
    15001 aaatgtttta aaaactgatt cagtagctac tttattgaat atcaaaccag aatcagttga
    15061 tccatctttt gctcagatca gtaacgtatt tattggtatt attgccggat tgattgcggc
    15121 agctctttat aatcgtttcc acgaagcaaa attaccgatg gctttatctt tctttagcgg
    15181 caagcgtcta gtgccaatct tggctgcctt tgtcatgttg ctgatcagtg cagtgctact
    15241 gctcgtatgg cctccggttt actctgcttt agtttctttt gctaaattca ttttgagttt
    15301 aggctggggt ggtgcaggtc tttatggctt cttcaaccgt ttactgatcc ctacaggatt
    15361 gcatcaagca atgaactccg tgttctggtt tgacgtagca ggaatcaatg atattggtaa
    15421 atttttggct tctgaaggaa caaaaggcgt aacaggaatg tatcaagctg gatttttccc
    15481 aatcatgatg ttcgggcttc cagcaggagc atatgctatt tacagaaatg cacgtccaga
    15541 aaacaaagca aaaacagctt ccttgatgtt agcagcagct tttgcttcat tctttactgg
    15601 tgtaacagaa ccacttgaat tctcatttat gttcgttgct tggccattat atgtcttgca
    15661 tgcaattttc actgggattt ctttagcagt gagtgcattc ttccattgga cagcaggatt
    15721 tgcctttagt gccggatttg tcgattactt cctatctttg aaaaatccga ttgcgaatca
    15781 gccattgatg ttgatcgtcc aaggattagt aacagcagtg atttactact ttggctttaa
    15841 ctttgctatc aaaaaattcc atctgatgac tcctggccgc gaggaagcag atctttcaga
    15901 tgacgatact gcaacgacta attcagacaa taaatatgcg gcacaagcaa gcaaaatcta
    15961 cgctgcatta ggcggagccg acaatgtaac ttcgatcgat aactgtacta cacgccttcg
    16021 tttgcaagtc aaagatacag gcctgatcga tcaaaataaa atcaaagcca ctggcgtacc
    16081 tggtatgaag atcatcgacg gaaaaaatgc gcaagtcatc gtaggtacag aagtacaatt
    16141 cgttgcagat gagatggcaa aactacatgg tggtgctgca acacgacctg cacaaacaaa
    16201 caccgtggtt aaaacagaaa catttgccgg tggaacgatc gaacaagata tttacgctat
    16261 cgcaaatggg aaactgattc caatcactga agtttcagat gatgtattcg cggaaaaaat
    16321 gatgggtgac ggctatgctg tattaccaga aaatggagaa atcttctctc caatcgctgg
    16381 tacgatcaca aacattttcc caacgaaaca tgctgtcgga atccaaacag atgctggtat
    16441 cgaagtcttg cttcatatgg gcatcaacac tgttgactta aaaggcgaac cattcacttt
    16501 atatgtaaaa gaaggtcaaa aagtcgcaag aggtcaattg attgctttag ttgatcttgc
    16561 cgctattcaa tctgcaggca aaaacacgga tatggtcgtt gtattcacaa atggcgacaa
    16621 agtccaaagc ttagaaatcg aacccgcacg tgatgtaaaa gcaaatgata aaatcggctc
    16681 tgtttccaac aaagcctgag ccatcgtctt ccccagactt ttttatcgat aaacaaacag
    16741 gagctgagac aaaaatcttg tctcagctcc tttttccgaa taaaaacggc gttctcctgc
    16801 caactccgcg gtaataagtc cagccaaacg taacatatga agagctattt tttatttgac
    16861 tcttcttatt acttgatgca gaacagcttt tttacaacct ctgataaacg gtgttcaaaa
    16921 accagtttat cggtatgaag tcaaatttat gcaaaaatgt ggaaagccat tttcacaaaa
    16981 tttttcttca tactcaaaac taatcggctt tttcacaacc tctttataca ttattcctga
    17041 tccaatattt cttttaatgc tgcttcaaga gaagttaatg gttttcccaa tactttttct
    17101 aaatcatcag aggaaatagc taactgatcc tttttaatat catgttggat cgctaaaaac
    17161 atgtcagctg cttcttgagg gaatccggct tcttttagat tttcgacaaa cgctgcatca
    17221 cttgcttcaa taatttctaa ctttttacct gtcgcacgct ctaatgcctt ggctaattct
    17281 tcatagtcag ttagattgcc ggataattct aagatttctg gagagtcact ttctactagt
    17341 acttttgctg cagcttctgc atattcacgt ttcaatgccc aacctgtttt tccatttcct
    17401 gcagcataaa cgaattgacc agtttttaaa gcctgcccaa tgataggtaa ttcattctct
    17461 acataccaat tattccgtaa aaatgtatgg gaaatacctg aatccttaat cattttttca
    17521 gtgaattggt gatctggcgc taatacactg atcgagtgat cggcatctgc aaaacttgta
    17581 taagcgatat aagatacccc agctgcttgt gctgccttca ctacattctt atgttcggct
    17641 tgacgatttc ctggaacgcc agagacaaaa agcaatcgat ctattccttt caacgcttct
    17701 ttcattgagt ctaaatcatc ataatcacca atacgtatat taaatccagc ttctttcagt
    17761 gcttctcctt tttcttcact acgtactagt acatagattt cattttgtgg aaccatcttt
    17821 tttaagaatt ccagcgcata accaccaaaa cctccagttg ctcctgttac taaataatgc
    17881 atatttgcca ctccctattc tttttatttg ttaagattta cagctgtaca tttataaatt
    17941 acacctttat cataaagagt gtggtaagat aagtcaagca aaaaaaatga aaggatgaca
    18001 actgatgaag tattctctgc aatttagtga tgcaatccat gtacttgcct atattgaaat
    18061 gtttcaagat acccgatcac tttctagtga gatgattgcc agtagtatcg aaacaaatgc
    18121 agcaaatgta cgtaaaatca tgagtcagct caaaaaatcc ggtttgatct ttacaaaaac
    18181 cggaaaaccg cagccttccc ttgccaaaag tccagatcag atttctttac tagatgtcta
    18241 tcgcagcatc gaaggtaata cacagcttat ccaagtcgat ccaaaaacaa atccaaattg
    18301 cgtcgttggt gcgaatatcc aagaagcttt agaagaaagc tacgctcggc tgcagaaaaa
    18361 ggcagaagaa gaaatggcta agatcacact tgatagtctg atacataaaa tagccgtttt
    18421 ggaaaaagaa aaaagaccag aaaacacagg cctcgtagag agatttttat aattctctct
    18481 actgtgcctg catttttctg atcggaatcg tctacataaa ttcttttatt ctccggggga
    18541 caaaagcctt gtcatgcccc tttttcctct ctaatgctca ggtcaaagcg ctgaagtcat
    18601 gacgtcttga taaacggtgt tcaagtagct gaccctcggc attagttctg aaaaatgcaa
    18661 aatatggaaa gctatttccc atttttcctc tctaatgctc aggtcaaagc gctactttca
    18721 cgacctctat attatcatgg tttattgact accggtatcc agatttctcc catatatttc
    18781 ccgttggtaa ctcccatttc gactacagca tttggacccc caacataggc gtaatcttct
    18841 acttctctta aaacatgccc aaaggccgta ttcgtcaaat catttcttaa ttcttcaggc
    18901 gattctgcta aagcgattac aacaagatac gttccttttg ggaatgggat gattcgggta
    18961 gtgtttggaa catcctgact cgtttgaaca ccgacatagt acatcatttt cccgttatag
    19021 ggttcgttga ctgtaaagaa ataatgattt tcagcagctt gtttcaatgc atctattgtt
    19081 ccattaccga taactttttg ctcaaatgct tgtttctctg cagccaaacc gacaaaatcc
    19141 gtattgctac tcttcaattc cacaccaata cccgtcaccg taaaatctgg tttttcttcg
    19201 atcctatact ttgccatttc tcccaccctt tctattatat taagttcatc ttacataaaa
    19261 ttaaagggaa atgacacgat tacgctcttt tttctaggga tatttttatt ttttaactat
    19321 ttttttgctt tcactgcaat ccaaatctca ctgtaaacat tactgaaatc ctctccccat
    19381 tttgtaaaag agatctcggg agcttcgact aactcataat ctgaagaagg aagccattct
    19441 gcatagattt tcccccaagt atcttgtaaa gtttggggaa atggcccttt attaggaaaa
    19501 atggcccaag tgtgttcttc tatagcaagc atttctaaat cagcgtacgg attttctttt
    19561 gtcgtagcaa agccaatcat gtgcatcaaa ctgccctttt cttccaagcg ggctccatca
    19621 aatccataag aaacgttgat tacttgattt ggatataaat ctcctaactt atgcatctct
    19681 tccctttgag tctccgtgat cgtctgcgct aacttttgta tttcttgatt gactccttca
    19741 aatttgacag gaactttttt cgccacacct gccacataaa actgttcttt cttttcgata
    19801 cgaaattcca tcgattttcc tcctctgaca tcaataaaaa atgtcaagcg tggaaaagat
    19861 ttttgtatgc cgtatctgct gatttctgaa ggcagatatc ctgaccaatc acgaaaagct
    19921 cttgaaaaac cttcgactgt ttcatatcca tatctaaacg ccgtttctgt cactcttgat
    19981 ccatctagga gatcgcgatt agccaaagcc aatctacggt ttttgatata gtccattagc
    20041 gacatccctg caataaacgt aaagatgcgt tttaattgat attcagagat tcctgtattt
    20101 tcggctatta ttttatagga aagtccttct gtcaaatgtt cttcgatgta atcgatcaat
    20161 tggttcagat ctttaagcat atttatcttc ctccttgctt gcctttttat catattatca
    20221 aagaaagtca attacttgat gaatcaggaa ccaatttagt cagatgtaga aaatgttgta
    20281 tggatctaaa gaaaattctc aagcagcgtt tcgtaacgga taattggtat tatctgccta
    20341 tctatgtttt acctttagaa aaataaattt tggggaagac acattctaag taaacaaagc
    20401 ggtaaaaata tcttttattc ccttagttaa tccgcttact acctactgta caaagcaaat
    20461 tgttgttcaa actgctgatc agaacgctgc ttggattttt ctttgcgata catcatacct
    20521 cttttatcaa ttggaacaat tatttatttc taacaaaatc acttcatttt tgtcagataa
    20581 ataaaaaaca aaaaaagttc catctttaaa acacgctatt cttttacttt ttctcacatt
    20641 ctctaagaaa agaaaaggag aatgaatttt tgacaattcg agcaaaagtg attatcaaat
    20701 atgtaaaatc agctactttt ttcttaaacg tttctttata ctaaatataa ataagtgttt
    20761 catgaaagga gaactagatg aataattggc ttgagtattt tcctgaaaac gttttggaac
    20821 gcggttacag ctatcatctg cacggttttg tccgtcattt gaactataca agcaagtact
    20881 tgtccgcaac agtttctggc acggaagatt ataaggtagt gatcacttgg gatgaaaaga
    20941 ccaacatgac ttgtgattgt ctatatgcca tagaaggaaa aaaatgcaaa cacatggctg
    21001 ctgtcttatt cgcttacgaa gaacgtccaa taaaaaaatc caactactca ctttccgaac
    21061 tctcgtccct tgtttcctcc gctagttcct ctcttgtacg ggagctttta acagagattc
    21121 ttatagaaca tccgcaattt atcgaacgct tcaaagttaa gatgccattt catgcaataa
    21181 attattcaga taaattaaca actatcatcc ataaatacga tcatattatc aagaaaaaca
    21241 aaaacaggaa aacagcgaag ttcatcatgg agatgcgaaa gttcatccaa gaagcagttg
    21301 aatcgctcat tcagcaaaat gcctatcttc ccgcattcga attgatcaat gaagtgattg
    21361 ctactctcga aacattctat tgggagcctg aggatgaacg aacccttctt ctgatagagg
    21421 actgttatta tttatggaaa gaattattag cagaagcacc tcatgcagaa aaaaggcaaa
    21481 tgttctcttg gttcgtctgc caagtcgatc atactgacgc ctcttattca aaacgctact
    21541 ccataaaaat cctgaaagaa gactttcggg aaaaagaatt ttctaaccaa aagaaaaaaa
    21601 tagataaaaa aactaaagaa acggtaaaga aagacgattt caatgaaaaa tagcaagtaa
    21661 acgataacaa ccatcctaaa tccacaagaa atacagcaga ccttgcttta aaaacacgaa
    21721 tcatgcaaag gatgaagtaa agaagactta acgcgtaccc aatattagtc atttgactat
    21781 taggtacgcg ttttgtttta taagtcatga caaatttcct tcgttgctgg gtagattttc
    21841 cggcattgtt gatagatttt atgatacttt tctacatttt gtaagagagg ttccactgca
    21901 tctgtatatt ggataaaatt ctgacaacaa ctttcaggtg tgtcgaacca ctctaatctt
    21961 taaagataaa tattaaaata acgattaata atattaacag tctttatttt tcaccaccaa
    22021 aaacctatct ttgcatatac taaatagacg tatatacaca gataggtttg tcttgtgaaa
    22081 aataatgatt atccttacca aaaaatgttt gtttttctac atgttcgtac ttatcaaaaa
    22141 atatgatcct tattgaaatt actggctatt tatattccaa cgacttcttg tgttaatttt
    22201 tgttatctca tagtaaatta tgtttcattt tcacttaatt tagttgtcac gtgttcgtca
    22261 attcgtaaaa acggtaaata tataaacaca cttgcggcta taattaatat ttgtaaaaca
    22321 gctgctcgcc agtctccggc tgttgctaaa aatcccgata taactggtgg cgtagtccaa
    22381 ggaatttgca ctactacatg attaattaat cccacagcag ttgcaaaata tgctactgtc
    22441 aaagaaaaaa tcggtgcaag cacaaaggga ataatcagac tgatattaaa tacaataggc
    22501 aatccaaaaa taataggttc gcttatattg aatatagcgg gagttaccga taatttagca
    22561 aagtccttat aatcttttct acgactgaag ataaatattg caatcaataa agcaatcgta
    22621 tttcccgatc cacccattac cgcaaaggta tctttaaagg ccatattgat aatatgtgga
    22681 atttgctctt tgtttgcata agctgccata ttttcttgca tattctgaat caaaaacgga
    22741 tctaacaatg aacctgatat tactgcttga tggataccaa atccaaaaaa tagattagca
    22801 atagatgtaa ttaacaaaaa tcctggtaaa ccagttgtaa ttttacttaa tggctctgta
    22861 actatcgtgg taattagctt atttatatcc atattaaaca attgaatgat tataaatgac
    22921 aataaagcaa acgaggtaat cgtaataatg attgggatta atacattaaa agactttaaa
    22981 acagcgggag gaatatttcc ggatagctga atctgtagtt tcttattatt agaaagttta
    23041 ataaataatt ctgtagccgc taatccaaca aatataccta caaacattcc tgaagctcct
    23101 gtataggata taggtatcac acccgtcact tcaacagctt tatccgcatt ttcaggagta
    23161 aacatcatct gcataggtgt taatacaaca aatgtcgaaa tagcaactaa taccgctgca
    23221 atatgatttg tataatttct gcttgcacac atatgataag atactgctgc tacaactaat
    23281 aatgtagtta tgcttaatgt accattggca attgaagtac caatttgttg taacgtggtc
    23341 aatgtactag tatcgacaat ttcccccatg aatcctgttg gttctaagat cactgaatta
    23401 ataagtgtca caaatcctgc taacatcata aatggcataa atgtagcaaa cgcatctcgc
    23461 aaagttctta aatggatctg attccccaac ttagtcgcaa ctataccaaa tttttcaaat
    23521 acaatgtcct tcctgctact tttgcccata ttttttctcc tttatgctta ttgtaatcga
    23581 ttactttttc cacccaaata atacatcact tatcaaaaaa agtaaatact tttaattaaa
    23641 tatatatatc ttttttagta taaaaaaata agctctgaaa aaataatttt cccgagctta
    23701 tttttcaaca aaaacagctt caaaaacaaa gtcttgatat aaatgtctcg ataccgaata
    23761 ctcgaaaggt ttaccagacg atagagcaac aactttgtct atctcaatca taaattcacc
    23821 tggatctatt tttaatattt ttgcgtcaaa ttcattcgca gtatctcctt tgatacgtat
    23881 gtgcgaagtc tttatttcca gacccagttc atttgtgata taagcatata cagatttctt
    23941 taaatgtttt ggttccaagc ctggtatgac tgctaatggc atgaatgttt gctcaatcga
    24001 gtatggttga caatcaataa aacggcttcg tacaatatta tatacatagt cttttacact
    24061 gatacttaat ttatcagcta cttttttcga tggaagttca attgagaaag tatggatttc
    24121 tgaatctacg tgttcttcac caaccacgct aaacaaacct tcgtttggac caagaactcg
    24181 tgagttatca attggtgttc tgacgacttc agtcccatac ccacttctac ttcgcaaaac
    24241 tccttcggaa acaagtaagt ctacgccttt ctttactgtt aacttgcttg tatgataaat
    24301 aactgccaat tcatctcctg taggaagttt ctcaccaatt ttatactctc catttacaat
    24361 ttttttcttt atatctaagt aaatttccat atacttcgca atttttttca atggtgaccc
    24421 tccaatcaaa aacatatctt catctatact ttaacataaa taaaccgata aaatccacat
    24481 caaaattata cacacaataa aaaagatata tatatttaaa caaaactatt tactttaagt
    24541 tgtaagcggt gttatcatta agtggaaaca ggaggtaaaa aaattatgac aactatgaaa
    24601 aagctaactt ttccagatga tttttggtgg ggttccgctt ggtcagctga gcaagcagaa
    24661 ggaaaaggag aaacaggaaa agcagagact atctgggatc gctggtttaa agaacaacct
    24721 taccggtttt atcaacgaat cgattcctct attacaaccg atcacatcca tcaatataaa
    24781 gaagatatag aactaatgaa aaaaactggg cataactcct ttcgcgtttc tatttcttgg
    24841 gcacgaatgt ttccaaatgg cggtaccgga aaagtaaatc ccaaagccat ttctttctat
    24901 cgaaaattat tttccgaaat gaataataac ggaatcaaag tatttgccaa cttatatcat
    24961 tttgacatgc ctgctactct tcaagataaa ggaggatggg aatcacgtga agtagttgat
    25021 gcttatgttc attacgctga aacttgtttt aaagaatttg gtgacttagt ttgtcattgg
    25081 tttaccttca atgaaccact tgggcctatt ttaggtactt atcttgaaga ttttcattat
    25141 ccaaacctca ttgactttaa acgcggagcg caagcagcat tcttcactat acttgcacac
    25201 gcaaaagcaa tacaagtatt taaagaacta gctcttccta gtaaaatagg cgttattcta
    25261 aatttgagtc ctacttttcc tcgtagtcaa aatcctgctg atgtgaaagc agcagaaatc
    25321 gctgatttat tttatacgcg gagcttttta gatcctatgg ttaaagggaa tttttctaaa
    25381 aagcttatcc tgttattaca agaatataat cagcttcctg aagattatac gaaagaagat
    25441 cttgtatgta tctacgaaaa taccgctcaa attcttggac taaactatta cgagccacgt
    25501 cgcgtcaaat ctcgttcttc tatggtggat acatctagtc catttttacc agagtggttt
    25561 ttcgaaccac atatcatgcc tggacgacga atgaacgaat accggggatg ggaaatttac
    25621 gaaaaaggaa tttatgattt gtgcatggat atcaagaacc attatggaaa catcgaagca
    25681 tttatctcgg agaacggaat gggcgttgcg gatgaagaac gtttcatgga tgatacaggg
    25741 caaataattg atgattatcg gattgagtat atcaaagatc atcttgctta cttatggaag
    25801 gcaataaatg aaggatgtaa cattaagggg tatcatcttt ggacatttat tgattgctgg
    25861 tcatggatca acgcctataa aaaccgatat gggctggttt cactcgacct tactactcaa
    25921 aaaagaacaa ttaaaaaaag tggcgaattt tacaagcaat taagtgatac aaatggattt
    25981 agatacgatg tagacttgtt agttgaataa tattctaaaa ttccacttga agtgaacaca
    26041 ttagaaaaca agaataatga gaaataccaa taacaaatac tttttcttca tacttcattt
    26101 atacttgtca gtataagaga ctgtgacaaa tgtagtgatc ctcagaagtt aggtctggaa
    26161 atctaacttg agaagatttt tttaaactac gtccagtctt ttttatttgt ttaaaattga
    26221 agttgacaag tcttcattaa aaatttagaa tattcacaag tttgacgaca attatgaaaa
    26281 tttatgtcgt gctaaaggag ttttgttatt ggatgaaaag ttagatataa aaactgcgat
    26341 caaagacacg ttacctaccg tttttggtta tatcggtatt ggacttgcat ttggtatcgt
    26401 tgggaaagct gccgggtttc atccgctggt cgtcacgttg atgtccctgc tgatctatgc
    26461 tggttctgcc caatttatca cggtcagcat gcttgctagc catagtccac tgctctccat
    26521 cgttctctcg acctttctag tcaattcccg aatgattctg atgagtatga cgattgctcc
    26581 ttatttcaag aaaaatcggc tgcttcaaaa tctgctgatt ggcacattgc tgacagatga
    26641 aagtttcgca ctgggaatga ataaattgaa ctatactgga caaaagttaa actttcgttg
    26701 gatgaataca gctaattgga tttcttattt gacgtgggtg ggttcttctc ttgttggcgc
    26761 acttttaggg aattttatta ctgatccgaa aaagtttggt ttggatttcg ccatcgtcgc
    26821 tatgtttatc gggttacttt atcttcaagt catttctgat agaaacacct ctaaacgatt
    26881 acagttgatc ctgattggtc tcactttgat tctggtatat gtcggactga tttttatccc
    26941 aagtaactta gtgattttag ttgtaacact gattgggtgc ggattggggg tgtggatcaa
    27001 acatgccttc ttttgagttt acattgctga ctattttagg ttgtacttta gcaacttggc
    27061 tttctaggat cctaccattt gtcttactga aaaaattcga tttgccgcaa ccgttgcttg
    27121 agtatttaag ttttgtcccg atcgtcatta tgtctgcttt atggttcagc agtctattta
    27181 cccaaaatat cggacatctg ccgcagatca atctcgaaaa tgctttggct tcagttccta
    27241 cacttttagc tgctattctt tcaaaaagct tattggtgat cgtcttggta ggaattcttt
    27301 ccctttcgtt gattcgctta ttataaataa aaaaacaaga gcttatggca aattactgtc
    27361 atgcgctctt gtttttatca aagtcaaata agaaaaaaat cggcgtattc ttgcttatcc
    27421 gttgaacgga ccactaacaa cgacttttcc taatatatgt cctgtttcta cgtctttggt
    27481 tgcttgtttc aagttcttcg cattcatccc atctgaatag accttgctca atgtactgcg
    27541 gataatccct tcatttgcta aagcagcaat gtgcgctaaa gcttctcctt gcgtttcgat
    27601 ttcatagtta tagtctgttt tagcgaacat atactcccag tcgaagctga tagattggtt
    27661 tttccaaaca cctatatcta acggctcttt gatccctacg atcgttccca catgtccaaa
    27721 tggtcggaca aggtgtttga tttgatcaaa gtagcgggta atatcgaata atacagcgac
    27781 atactctact tgatcgattc ctaattcacg aaaactttta cttaagtcgt gatgataatc
    27841 gattggatag tctacacctg tttttttcag ccattcaaaa ttcttcggac ttgcagtcgc
    27901 gtagacttct aggccagccc aatgcgctag ttgattcaaa atcgaaccga cgcccccagc
    27961 tccgttgatc actaagattt ttttcccgcg gttggcattt tcttctggag tcagaccaaa
    28021 tttttcaaat aacaattcat aagcggtcaa tgaggtcaac ggcaaggctg cggcttcttc
    28081 atctgaaaga ttttttggtg caagagcgac aatacgttcg tcaaccagtt ggtattcttg
    28141 attgcttcct gctcttgtcg ttgtacctgc gtaaaaaacg cgatcgccga cagaaaattt
    28201 ttgcacttca tcacctacag caacaacttt cccgactcca tcaaacccta agatacgtaa
    28261 agcatttctt atcccgttat cttggcgaag tttcgtatcg acaggattaa cagatactgc
    28321 gttgactttt accagaagat cccgtgaact gggtacaggt atctgttctt tttcatcaat
    28381 aaagcttttt ggatcatcga tcgacaaccc ttcataaaaa ccgactacct tcattaattc
    28441 cttttctgac atacgaattc ctccttagct tcatcaagtt ggagcatcca tacagttttc
    28501 atttcaatat atatagtatg ctatttgttc cacttttatt catcataatt attctcttac
    28561 ttaaagtaaa ctatttgcac ttttttggtt aaaaaagagg ttgcgacaag acttttgtca
    28621 caacctcttt taaacggtgt tcaatcaact gaccctcggt attcgctcaa aaaacgacaa
    28681 aatatgagga gctatttttg tttggctgtt cttattactt gatgcaggac agctttttca
    28741 cgacctctaa ttcacggtgt tcaagcaaga aatcattgtt cactgaaaag cgttggatgt
    28801 tctttttcaa aggtgtctaa gatctctcgt acttcatcag tagatttcgt attcatcaac
    28861 tgaactcgca agtcatttgc tcctggaaat cctttgatat agattttaaa gaaacgatgt
    28921 agtcctgtga tggaacgcgg gatgatttct gaataatgat cttgcagatc tagttgcaga
    28981 cgaagtagtc cgatcagttc tttttctgta tgttccctcg gttctttttc aaatgcataa
    29041 ggattcttga aaatcccccg gccaatcatg atgccatcta cgccatattt ttcggccaat
    29101 tcttctcctg tctggcgatc tgggatatct ccgttgatcg tgatcagtgt ttgcggagcg
    29161 atttggtcac gtaaagcaat gattttaggg atgacttccc aatgtgcatc tactttactc
    29221 atctctttac gcgtacgcaa atggacagaa agattggcta tatcttgatg aagtaggtga
    29281 ctgatccatt cttccatctc agacatttcc gtatagccga tacgcgtctt gacgctgaca
    29341 ggcaaaccgc cagctttagc cgcttcaatc aattgtgccg ctacttctgg gcgaaggatc
    29401 aagccactgc cttttccacg ttctgctaca ttagggactg ggcagcccat gttgatatcg
    29461 attccttgga agcccatttc tgccatagca atgctcattt ctctaaaaaa ttctggcttg
    29521 tctccccaaa tatgggcaac catcggctgt tcatcttctg taaaggtcaa tcttcctcgt
    29581 acactgtctt ttccatctgg atgacagaaa ctgtctgagt ttgtaaactc agtaaagaag
    29641 acatccggtg ctgctgcatg ctttacgaca tggcgaaata caacatctgt tacatcttcc
    29701 attggtgcta aaacaaaaaa aggctttggc agctctttcc aaaaattagt agtcatttat
    29761 ttgttactct ccattctatc aagcagtgaa gtcgcaatct ttctcaaaaa cattgtcatt
    29821 atactaggaa acaaaaaaag aagcaaagtg aacagcttaa aagatgtttc tgattgagca
    29881 aaaaaagact gtgacaaaaa tcttatcaca attccttttc cggaataaat ggtgttcaaa
    29941 agcttgcatc tgcggtaata agtccaacca aacgaaaaat aggaggagct atttttgttt
    30001 ggctgttctt attacttgat gcagaacagc tttttcacaa cctctccact aaacggtgtt
    30061 caatcagctg accctcggta ttagctcaac aaacgacaaa atatgaggaa ctattttccc
    30121 gtttgtttct ctaatactca ggtcaaaacg ctgatttcac aacctctttt ctaacttctc
    30181 aatcctcttc ctttattgat caaataccaa gtaacggcgt acaaaacaac gatgaatagc
    30241 acaagtacga tcatcgatgt tgctactggc acatcgattg ttccaaggaa tccgtaacgg
    30301 aaaccgaaga tcatataaac gatcggattg actttcgaaa cagcttgcca aaatggcggc
    30361 aacatagaga tggcatagaa aacgccacct agataagtta acggctgcaa gacaaatgta
    30421 ggcacgatcg atacatcgtc ataagactga gcaaaaatcc cgttgagcag tcctgctaac
    30481 gaaaacaaga ttgccgtcat caataatgta atgatgacca tgaaccatga atacacatga
    30541 agtggtacaa agaacaagga aatgatcgtt acgagagagc cgacgagaat actgcgaccc
    30601 actccgccaa tcacaaagcc ccaaatgatc acatgcgtag gaacaggcgc taccaagatt
    30661 tcttcgatgt ttttctggaa tttttgagag aagaaggacg aagaaacgtt ggcatacgaa
    30721 ctagtgatag cagacatcat aatcaaacca ggcacgatga attccatata tgaaaaacca
    30781 cccatgtcac cgatccgacc accgatcatt tttccgaaaa taacaaagta caaggatgtc
    30841 gtgatcacag gcggaaccag tgtttggacc cagatacgca aatagcggtt cgtttccttg
    30901 atagctaaac tttttaatgc agtaaaataa agattaaaca tttttctcct ccgtatgatt
    30961 attttcttct gtgattttca aaaacagttc ttctaaacga ttcgacttat tcctcataga
    31021 aagaactttg attccttgtc ttgtcagctg atcgaagatt ccgttcaccc cttgatttcg
    31081 ttcaacttcg acagcgattg tctgttcatc ttcaaatgta caagcgtatc cttcaatcac
    31141 aggtttggtc tcatatggcg ctaaatcaaa gataaatgtt tcaaattgca gtttggatag
    31201 aagctctttc atactagtat tctcgatcag ttcacctgat tggatgatcc cgatgttgcg
    31261 acaaagcatt tcagcttctt ctaaataatg cgtcgtcaaa atgatcgttg taccattttc
    31321 gttcaattct cggagaaact cccacatctc gcgtctcaat tcaatatcga ctcctgctgt
    31381 tggttcatcc aagatcagca aacgtggttc atgcatcaat gccctagcaa tcatcagtct
    31441 tcgcttcatt cccccggaaa gcatacgtgc acggacattt ctcttttccc aaagattgga
    31501 ctgcttcaaa tatttttcgc tgcgtttcat cgcttctttg cgagagacac cgtagtagcc
    31561 tgcttgattc acgacgattt gctggaccgt ttcaaaggga ttgaaattga actcttgcgg
    31621 gactaatcca atctgttgct ttgctcggac tagatccgta tccagatcat aaccgaagac
    31681 attcactttt ccagatgttt tattgactaa agaagtaatg attccgatcg ttgtagactt
    31741 cccagctcca tttggtccta atagcgcata gaaatctcct tctttcacgg aaagatcgat
    31801 tcctcgcaat gcttcgaccc cacttccata aacctttttc aaattattta tttcaagcgc
    31861 atttgccatt tatttcctat ctccttatag acatgattct ttattgtatc atggaataca
    31921 gcagatgaaa aaacaacttg gttccagcga aaaatcaggt tgctgggctc aggaaaatct
    31981 cctaatgaaa gacatcaatc ggacgaagtc agacaacctt ttcagaaaaa acaaatcgaa
    32041 gataaaggat tactattcat atgtgcaaca aaaggagcgt gagacaaaag taaagaacac
    32101 ttttgtctca cgctctaaac acgtataaac ggcggaagca aaagccaaga tttttgatcc
    32161 aataaatact ttcgatcact tcgcctatcc caatacatgc cactgccgct tttcatcaaa
    32221 taacgcggct tccgtttttg cggtttctac taaagtctct gggtaatcca aaactttcag
    32281 caaggcaatc gcatttcggg tccttgaagg tccttctttt aatttgaaat caaaactgat
    32341 tccttttcct tctgttactt gttcttcaaa gtggacattc tcacaataat tctttaaaat
    32401 ctctgtcaat tcgatatcat gtgtggcgac aaatgctaaa gatggatact ccgcaagcca
    32461 ccgaacgact gaagcggaag aagcaatccg ttcgatcgta tttgtccctt ttaaaatctc
    32521 atctacgaag cagtagcagc gttctttgga agccacttgg tccaacaaac gtttgatcga
    32581 tttgatttct gaaacaaaat aactgtcgcc ttcaaataaa tcatcttcga ttgccatgga
    32641 agtcaacaca tgtccaggtt gcagggtaaa ctgttctgca atcgctgttt ggatcgtctg
    32701 tgctagaata cagctgatgg ctatactttt gacatacgta gattttcctg atgcattgga
    32761 acccgtgact aatgtattct tctgccagtt gaccggattc actaccgctt cttttaacaa
    32821 tggatgatag atatctttcg ctgtcacacc gccctcagta aactctggtc ggcaagtgat
    32881 gggcatataa gtacggtaat tcaatattgc agcggctact tctaattctc ccagcaattc
    32941 ccacagcttg atggcttcag ttgaatgctt ttctaattta gtgagaacga aatgatagga
    33001 gataaatggc agcatgaaca tgatgttgac atattcaaaa atcaactctg cttcactccc
    33061 actcttcata cgaaatgaaa aacctaattt agggatgtct cttaatggtt tagtttgctg
    33121 tttcagctct tcttgaagtg gtgtcggcag ttttgctagc tgattggcgg ctgaaatcgt
    33181 tgaaaccaaa taactcatgc tattcagctc tgtttctagt gtttgtttct tcactagata
    33241 atagaccgta ttgaatacta acccaccgat tgccaaatag attcctagta cttgtcctaa
    33301 aagaagcaaa cccaaaccca ccagcggaag caagccaaga aaaataaata aacctacgcg
    33361 tccaatcttt ttactttttc catccgctag atattgtttt gcaaaattat gatctttttt
    33421 tcctaaacga gcgaattgat attggatttt ttctctcagt tgaggatttt cctgataaaa
    33481 agcaatcagt ttttctaact gctgatcttc accaaaatca aagctgcgta aacgttgata
    33541 caacgcttct gaacctacac tagaataggt actgttgatt ccttcgaata cttcgaacat
    33601 atccaggtca taccaagtaa gatcatcgat ttcgctatcc catgaacgga acttcttctc
    33661 cgtgagccat gcttccttca agctttcttc tttatcaaat ctcggttgat aaggaatttt
    33721 ttcccatttg ctacgaactg tttcctttaa tttcaaacgt gaaaaaatgt ctaaagcaac
    33781 taataaaata acagctgcaa taataattaa aacgataaat tctctttgac ccatatccct
    33841 ctccgttcct ttatttgtta gctttagtat agcactgttg cgctatttga aaagagggta
    33901 aaaaaacacc tttcaaaata aaaggtgttt ttttcttgta tattacatat ttatctctca
    33961 tttatcaaaa ttgacaaata atcataggga ggaattgttg ttaattcttg tttattctcc
    34021 agtgcattga caactgtccc aagggaaagg atagcctcag gtactatttt ttcttgttct
    34081 gttggattag ctaagcgaag aacaaatcct tgttcatgaa aataagaagg ataaatcgat
    34141 gatacaatta agtcttcagg taattcaatc aatgaaaatt tacgaggaac atcaagttca
    34201 ttttgtaatg gccaaatctt gttatctaac ctgtgaataa atacattcag tttctgcttt
    34261 tgataagaaa tagattgttc taaccgtttt tctgcctgtt ttgccacttt gaactcatta
    34321 aatcttcctt cttctacatt aaatccaaaa gtgactttat actcacctat ctcttgagct
    34381 agcggtgttt ccatcatgac atgcccttca tttgtcgtat ctcctgaagc tcgcccaggt
    34441 cgccaagcaa gattaggttt tccaagttcc cctgttgttg aaaataaggt tatgattaat
    34501 tgattttcta tacgttcata ctcttttaaa ccatctgcat aaaacgtaaa ataatgatca
    34561 ttttctgcca cagagacact cttatcgaat atttctaaat taacaggttt ctctaccata
    34621 gtttctgacc aattcggagg aatgacatca ggggtatttt caataaatcc gttttgaatt
    34681 tgtgcaattg atttttcaga tttatctaaa acattaattg ctaagcgcat acgatgcgag
    34741 taaacagtat tatgaatttt gagtgtgcct tcaacgattt gactttctcc cagactgaac
    34801 gatatttcat aagatatttc ttccatttcg ggtttttcag ataaacgatc ttttaaatct
    34861 ttaggaagtt gagcttttcc gtaaacaact aatgtttctt gtaaagaatc tttatatact
    34921 ttagctgttt ctaattttag agatagttct gtatctcctt ctaatggtga ataatcatac
    34981 gtatcgccat catttgctga atcgatcaaa tgaacgaaat caagatattg tctatctcca
    35041 actatcaaat tcaattgccc atctttaaaa gaaagtttat atttattgtt acttatctca
    35101 gttttgtcta tctcgattgc tgtttctaat ttttcattat ttttctcaaa ttcaacaaca
    35161 gtgtatccta gtgctggcac atttacattt atttttatgt caagttcata ataagctggt
    35221 tcatcaaaat attcgaaacc tgtagcaatc atccgataag catttttccg ttctggaaaa
    35281 taaacttctt tttcaatgat attataggga ctacctttga agtgtatttt ctttgaatca
    35341 gctactacat gcacgatttt cgatccacta taattctcag tcgttgtgtt gaaaacaagg
    35401 acttcattcg attttagctt taatgcatca gccatccgtt ttacaataag gttttcgatt
    35461 ccgtcagcta tctcattagc ttctttgatt cgatggaaaa tatcttccgc aacattatct
    35521 gaaacacagc caccaatact atcatgagcc tggttttgca aaatcttttt ccataaccga
    35581 cgaagtaggc ctttactgat atggatacca tttctttctg caatcagcat gagcggctca
    35641 actcgtttta gaattttttg ttccaattta aaattttcta ttttcatttt tgttcttact
    35701 gagccaatag aacgatgaac acgagagtaa accggctgac gaagttcacc tttatattca
    35761 ggtaattctt ttttgtttct gataacttct acataagaag gataatctga aataatattg
    35821 tggaatttac tgtatttatt caacttctct acgacttgat caaaatttaa aatcattgac
    35881 ttttgatcta cacccgaagg tactaaaata tctttgtttt ttccttgcat atgaagcatt
    35941 tcaactgctt catccaactt ttcttttgca aattcaggaa tatctttaat tgcgtctaag
    36001 gtcatcattc cagtcatata accaaatgga aaattcatgg cataaacaaa tttatctccc
    36061 aatcctttcc agataaaata aggagatgga accatcgttt caaagtttaa tcctcgccaa
    36121 cacatgaaat tatcgatttc tacttgatgc aaaagtgtag gcaaattcgc attgaaccca
    36181 aacgtgtcag gcaaataccc taccatcatt ggatctccat atttaaggat cgtatcactg
    36241 attccaatca ttaagtttct taaaattgat tcagcatcca ctaataaggc atctgtttgt
    36301 gcataccacg gtcccacgaa tagttgtcct gttttcatca gtcgttggat aaccttaagc
    36361 ttttgcggat tgatctccaa atactcatcg acgattgaag tttgtccatc taaacaaaag
    36421 tttactttag ggttcctttc caattcatct agaacttcag taaagacctg atcagacaat
    36481 acgatggcat cttcatttgt aaaataccat tctctgtccc agtgcgtgtg ttgaattata
    36541 tgtgcattta ccatatcaga ttctcctact ttccttcttc tactgaattt acttgttgtt
    36601 cttttttata cttgatggat tttagtgcat tgaccattaa cgctgtaacc actcccccaa
    36661 taacaattga tactaaatat aaaggtatat tcgtaacaaa aggaattgcc ataaaggttg
    36721 aaagcattgt ttcttgagta acaccaaaaa atccatttag accacatgct actgcagtgc
    36781 ccaccacgat gcttggtatt actcgtaaag gatctttcac ggcaaacggg atcgtccctt
    36841 cagtaatccc cacaaggccc ataatcatag ctgtctttgc attatctcgt tccgattcat
    36901 cataaagttt tttgtttaaa attgttgcta aaaacattcc aaatggcgga atagcaattc
    36961 ctaataacat ggctgtacta ggtccaaagc ttccgcttga aaaagaagca accccaaaag
    37021 catatgcgat tttattgata ggtcctccca tatcaaacgc catcattcct cctaaaatag
    37081 ccgacatcaa agcagcattt gctcctgaca tgccttctag ccaattagtc agtcctgttg
    37141 tcattgcttg aataggcgta gctagtacat accataatat gattccaaca actaatgtag
    37201 taacaaaagg aatcagcata attgatttta gactaataac ttgcatcggt acttttactt
    37261 ttttcaatgc attagctaaa tagccacaag ctaatccagc aaccattcct ccaataaatc
    37321 ccataccaag attttgacac atcatcccag tgataaaagc tggtgctaga ccgggacggt
    37381 cagcaattga atatgcgata taggctgaaa tcatcggtac gataaactgt aatcccgtct
    37441 gaccaatcat tcgcaggact ccccagaatg tatccgtctg gtcccaaaca cctgtgccac
    37501 caaaaatgac tgcaatagaa gttagtaacc ctgctgctac gacaagcggg atcatatagg
    37561 aaaccccact ttggaaatga tttagaattt ctcttccttg tttcttgaat tccattagta
    37621 actcccccac gatatatttt ttatttgtta attaatgcaa ttgcttcatc aatcgtctct
    37681 tcaccatctt ttactacctc tgaggtccct actgttaaaa tcggtttacc gtcaaagcga
    37741 cctcgttctg aaacatttgt atctactgca aatatgacaa catctgcctc ggaaacatcc
    37801 gaaattgaaa gtttgttttc tatccccata gccccctgtg tttctacttt aatatctaac
    37861 cctttcttct tcgcaaactt ttctaaatta gcttttgcca tataagtatg ggcaatccct
    37921 gcgatacatg ctgttactgc tactattttt gtcatatgaa attcctcctt ttaaaatgat
    37981 agagctttta ccaattcttt tttatttctc gaatctttta ttcttttaac aaactcgtca
    38041 tccatcaatc ttccagataa ttctgctaaa atacgtaaat gattagtacc tttatcagtg
    38101 tcttttattg ctaacaaaaa gacgagatca actggttgat catctaatgc gccccattca
    38161 acagaccgct ttaacttggc tacagccact gttgattcaa ttactgctag gcttttgcca
    38221 tgaggaatgg cgatattttt cccaattcct gtggtcatat ggttttctct gtcaaatacg
    38281 tctttttgaa attgtttgtg gtcagacaca aacccattag tctctaacaa tttcgataat
    38341 ttttcgacta cacttttttt atcagatgca tttaaatcta tcactatatt atttatattg
    38401 attttttcac tgatcattta taagccttct ttcaatatat aaactaattt ttcaaacgac
    38461 gaactcgttt ttaaatttgc taataactca tgattcgaag cgatttcatt gaatgtttca
    38521 taaattttat tcaattcagg ttttactttt tcattaagtg caaaaaagaa aacagaatga
    38581 acaagtgtcc catcccaatc aattccttct ggattaacgt agacacagat tactggcttt
    38641 tttataaaat ctacttcgat atgcggcata gcaaaatcat tcatcgctgt tgaagatagt
    38701 ttttctcttt tgattgctcc ctctagtatc ccttctttcg cgtaattttc ttttaccaat
    38761 tttttggtaa ttatatttaa aacgttcact tgattatcct ttatttggtg ggtaaaaaag
    38821 caaaatcgtt tatctaataa atttagaaaa gcatcttctg tttgttcatt taactgtaga
    38881 tactgtttta cttttctgac atctgcccct aacatcaaag gactaacaac aataacagga
    38941 aaatttgtat tttcaatcgg aatcgtgctt ataacaagtt catcagtgac ttttctatct
    39001 tgtagttcat tgatgcttag tacatcttct atctcaacca tatctgcaaa accgttattt
    39061 attctttgct ctaataattt tgatgttcca tatccgctac tacaaactaa tatcactttc
    39121 gttttgtcag gtttgtaacg atccaaaagt gattgaatat ggagtgttac gtaagcgatt
    39181 tcatcttcat taaaatgtat acagaatctc tcttcgattt cctctaataa atctacactt
    39241 atcataaatg accttttaaa agaatatttg attttgtccg tataagggtt atagatattt
    39301 actcccaatt tgagtctttt aactgctgca ttgagatgta atactagatt attgatcaat
    39361 tcttcatcag gataaaattc atttaattta attcttacta actcttgtag ctcaacaccc
    39421 atatctaaat aggaaagctt cgtttgatct aagtcgtgat tcatagcatt tttttcaatc
    39481 gaagtaatgt gaatgtcaac ataagcttgt tcatctattg gcacaataat tgaaaatgct
    39541 ttttcaatca ttttgattaa aataagtgta ttctttgaga tttcttcttc agaattatta
    39601 ctacgtgata agaaattgct tgtttcaatc ctttctatcg caatagcaag gtggatagct
    39661 aaagtttgaa attcataatc tgtaaatttc aattgtgtct tattcatgta tcgattaagc
    39721 aattcggcta cttttttcaa tatgtcctta tttaagaaat tattcgcttc accaatgaaa
    39781 ttgatattca agtctaagag atctgtttta ctgttagatg ctgtaaagcc accccaataa
    39841 tagttcacaa cttctgacat caaccttctt ttactttttt catcagcttt gatgcgcacg
    39901 ccatttcgat ctgaaactaa ggacatccca tgcttgttta gtctttttct aacatctttc
    39961 attgtgcttt ctaccgtcga cctgctcacg tataattcgt cagcaagatt ttgaatcttt
    40021 agagaatcat tagtattcaa taatttagca aacacataag ttagacggtc ctccggagag
    40081 tctgcgatat tgattttatg actggataat aaatttcgaa gtgtttcttt ttttccaata
    40141 agcgaaacgc cttttttagg ttgaaccaac atttgtacat ctggcatttt ttggattatt
    40201 tctttcaaaa ttaaaatatc tttgctaatt gttttcgtag atacatataa ttgttctgat
    40261 aattctttgt aagttgtgtg ctcattttca atcaaaaagt atagtatttt catttgccgt
    40321 tcgctaaatt cgatgcccat tatcttcacc tcctgaatac agcttaagtg tacaattatt
    40381 atctctattt tcatacagaa gaaagttctt gattaatgta gaagtttcta atattcttga
    40441 ttatttcaaa tcaataaaaa agcctgcaat atttatatca caggcttttt tctctattaa
    40501 atatatataa gataatacat ttttctacta gttctcacta atcttgtata attaaaccct
    40561 ccgcaacttg acggagatgg agaagatgcc cccgtctaat ctagcggtca tctctcctcc
    40621 cattccttcc accaattttt ttgacaggta aagcccgatt ccgctagatt ccgtatttgt
    40681 gcggctggta ttttcggtat aaaaacgctg gaagactttt tcaacagagg tttgcgttcc
    40741 tggtttgata ggattggcca ctgttaatcg aatgaatgga tcctcttttg aaaatgtcac
    40801 ctttgcttgt ccatctgcat aacgcaataa attctgtatg atattttgca gcactcgcag
    40861 caacatgagc ggatctgcta atacagttgt atttatcgag tgttcagcga acgctacctc
    40921 gatatttttc tcagaaaatt gttcataaaa agagaaaaat acttcttcca cctctttaga
    40981 aaaagaaagc gtatggagat ccatttcttt ttgcttcgtc tctattcgag caagatcata
    41041 aaactgatcc gtcatactga gtaatcttgc aacagattgt ttgatgatcg ttaaatactt
    41101 ctcccgtttc tccgtatcct ctacctgttc cagtaattgt acataaccgt taatagcagt
    41161 caaaggagtt ctgagatcat gagaaaggcc gacgatcgat agtctgatgt tttcttccat
    41221 ttcttgaaat gcttgtcctt tttgttcatt ttcatccaac catgtattca gtgcatctac
    41281 taggtccatt agattctttt ctcgaaattc gactgaaaga cgaccaccat attcttgtcg
    41341 ttcagaaaga gtggcgattt tcttagttaa tctcttgatt tccctttgca ggaagaaaat
    41401 aaaacttccc ataaagataa caacgagaag caacagccat ttaatcaaat ctaaacccca
    41461 ctccccacac cgtatgaata tacacagcat gtgcctttgc tagcttccct cgaagattgg
    41521 aaatatgcat attcactgtt ttctcactat caaaatatgg ttcttgccaa actgtttcat
    41581 aaagatttgc tcgcgaaaat acttttttcg gatgttctaa aaaaagcttc agcagatcga
    41641 attctcttcc tgtcaaatgg acagccacac cattcacatt tacatccctc gactctttgt
    41701 ccagtaagat ttccttgtaa tagatgcgtt gcgacagatc ttttacttgg acagaagtct
    41761 gatgacgaag ttggatgccg attcgtaaca aaagttcttc gatatcaaat ggtttcgtca
    41821 catagtcatc cgctcctgct gccaacaagg aaactttatc tctttgatcg ctttttgctg
    41881 aaagaacgat gatcggaaca ttcgatgtct gtcggatttc tgctaacaat gcttcacctg
    41941 aaagccctgg aagcatgaga tctagaagga tcaaatcgac aggatatgtg cttaacaata
    42001 attttccttc cgtacctgaa taagcatcaa gaagtttgta tctctgttca agaacctcct
    42061 ccagtaagga atgaacagct tcatcgtctt cgataatcaa aatagtttcc agcaggacca
    42121 cctacttaat gtcagatttt tggaaaataa acattcctag agctgatgat accacgattg
    42181 ttactagact gaccagaatc attttcggtg cttgcgaata agttgcttgt tgcgcaaagt
    42241 ccgtatacat gagccacgtt tccgtaaacc actccgttag aaattccaag cctttgattt
    42301 ttgcgaaaac accgggaatg aaggccgttc ccatgatata aagaaaagaa agaagcaaac
    42361 tgacactggt acttctagtg atgaatgtca aagccactgg aacagataat gtccctaatg
    42421 tcagcagaag caatacagga aatactttta gaacataatt tccatagttt ttgattccct
    42481 caacttcacc aaatccgaaa gcaagtgtgt aagcaagcat ggctagtccc gtgatcaaaa
    42541 ccacgccaag tgttgtgatc aaaagcgtaa cgagaagttt cgacacataa taagtcattc
    42601 gattccgtcc taaagataac gtattgcgaa tcgtaccgtt ttgaaattct tccccaatat
    42661 aaaagcacgc aaatgctgcg aaagccagaa gaatccatgc agccattttt tctaccatta
    42721 aaatccctgt tgcaccgttg atgactgtat ccgttgcttg gtttaattca ttgccgtatt
    42781 ttgtatgcat ataccattcg ttccaagaat aaaaaagcgg aagtacgacc atcagtccta
    42841 gtgagaccca cattttacgg ctcttccata cttttatttt ttcagcagtt aatagattaa
    42901 acatgtggat tgcctccagt taattgtaag aaataatctt ccagtttttg cccaactagg
    42961 tgaataccat ccacaggaac ttttgcttct accaatgctt gattgatggc tgctacttgg
    43021 tcaattcctt caaaaagctg gataacacgg ctagattgta caaaataatc cctataacca
    43081 agagagtcga gaaccgttac tgcttgttcc gtcgccgaag tgtcaatttt tataaattga
    43141 cgagattctt gtgccaattc ttctttcgat aattctttga tcaagtgtcc ttcatgcaaa
    43201 ataccatagt gagtggcgat ctgtgacaat tcatctagca agtggctaga aagcaagacg
    43261 gtgatgcccc gttcttttac caaacgttgg atgatttctc gcatttctgc catccctgct
    43321 ggatccatcc cattcgtcgg ttcatccaaa atcaaaaatt ctggattcgt gatcagtgca
    43381 tttgcaatag ctaaacgctg gcgcatacct aaagagaaat tctttgcttt ctttttccct
    43441 gtattttcca atcgcatcat tttcagcagg tcttcgattt ctctatccga cacaccgccg
    43501 ttcgctgctt ggatacgtag gttatctctt gcagttaatt ctggataaag agcaggggtt
    43561 tcaatcgatt gacccatacg tcgtcttgct gcctgcaaat ccgtcgttcc aaataattcg
    43621 atcgaacctt catcaatcga gatcaaaccc ataatagttc tcataaaggt agacttaccc
    43681 gctccatttt ccccaatcaa tccatagatc attccacgtt tgatttcgat tgatacttta
    43741 tctaatgctt tggcagcacc gtattttttg gttataccag ttgctttcaa gaccgtttca
    43801 tttccaaaat ccatacttat ccttctttct tattgatgag tgaagtatag ttgacgggta
    43861 taaagaaagc agccagaaat gtataaagaa agtgtaaatt ttccaattga atgtcaaaaa
    43921 aaacaatcgg acaatacgtg tctttcctat tatcaggcag tttgttatac gcttgtatca
    43981 gtttcctgat tctttctttt cgaccaaagt cgtttctctg tattcctctt cactgaaaat
    44041 ttttgcttct ttcagatcaa gcttgagtaa ttttaccaga ccggttataa ggataactat
    44101 agcaagactc cctcccagaa aaattagact gtctcgcaga cgtggttgcg ttgtcttcca
    44161 atcaaagagc gcaccaaaca gtgctaatcc aagtggactg gccaccatgg taatcgttgt
    44221 tatcgttgac ataagtcgtc cttgtatatg cgttggaact tctcgctgaa gccagaccat
    44281 ataaaaagca aaagaaaaca ttaatcctta aaaacggact tatgaaaaat aatacatgcc
    44341 gtttgggatt tacaattagc taccaaataa gaggttatga caaaagactt ttcacaatcc
    44401 cttcttccga ataaacggtg ttctcctgcc aactcctcgg tcacaagtca caatatttat
    44461 caaacatgag aagcaatttt tgtaaattcc ttcttatttc ttgaagctga ccacttctgt
    44521 cacaacctca gaagcggata aataatattg tttgatgata ctttatcttt ttcccgtttg
    44581 tttatagatc gaatgatatt atagaccaag aatcctacct attaacatag ctaaaaacac
    44641 aaaaaaggca ctttccaaat tgtggaaagt gccagaaaag ttaggattaa ggtaactgcg
    44701 ctcagcattg cttcgcccag tacgattctc gtaactcgtg aactcgaacg ataatcgcaa
    44761 ttaacgtttt gagaactgtg aagctttacg ggctttctta agacctggtt ttttcttcgt
    44821 atcattgaat aagtttgaaa aaccttgatt tataaaggtt ttcccgtaaa tatattttat
    44881 tatatttgat taaatttgaa atgtttgtgt tctaaaatgt gttctaattt aaaggcagta
    44941 tatttcgtat tttagattaa atttttaggc tcattcattc tcaaatccat tctattcagt
    45001 caataaaaat tttaaaaaga ctttataaac aaagatgttc aagcgagcat cttatttttt
    45061 tgtgcttaat ttgaaaggag aacatttcat gtataaaaaa caaaaaaaga aattatgtgt
    45121 attaactatt ttgagtttgg ctgttcaagc aattgttgga gcaattgctc ctacgattac
    45181 ttttgctgat gaaattaccc atccacaaac ggtaaccgta gaactagatt tagcacatca
    45241 atatgctgtt gaaggaactt ttagtgatgg tcgtccaatg tcagaagtca ctgttccgca
    45301 ttatgcagtg tacaacggct ttaaacaaga tattttctgt attgaaccag gagtcccgat
    45361 ttacaatgag ttcactcctg gctatgagaa aaacccgtta ccagatatgt ccgataaagc
    45421 caaattagtt tccgttttat ggaaaaaagt aggtacagat gcagatactc atattgtggc
    45481 acagaagatg atctggcaag aagttaatgg gtataccctt cactcaataa aacgatcaga
    45541 tggtagtgcc gtaaatatcg cagccattga ggcaaaaata aatcaagcca ttgacgatta
    45601 tcagaagaaa ccaaccttcc ataatagtac ggctaaaaca gtattagggc aatcgactac
    45661 tgtgacggat acgaataatc tgaatttgtc agagttcgat gaggttgtgg aaaatgccgc
    45721 aaacattgat tatcgtgtga atggtaatca gttgataatc accccaaatg ccaattcaaa
    45781 agaaagtggt gtgctgacgc ttaagaaatc tgctggtacc ggaacacctg tcgcctataa
    45841 aaaggctggc caacagactt taatggccgg ggcgattgat aaacctaata cctacacaat
    45901 caaaattgat gtggaaacgg agggttcttt aaagatcaaa aaagtcgata aagaatcggg
    45961 tgatgttgta ccaggaacgg ttttccattt agactttgga aaaactttac ctgcaaaaga
    46021 cgtgactact gacaaagaag gcattgctac attggatgag attcctcatg gtacaaaagt
    46081 aaccattacc gaaaaatcag taccggcgcc ttatacgatt gataccaccc ccatgactac
    46141 caccattaaa gcaggcgaaa ccatttacgt gacttcaaaa aacgcacggg aaaaagggca
    46201 aatcattctg gataaaagcg gagttgaaac agggagtgat ctttggaatg acaattattc
    46261 cttagctggt aatacgtttg ccattcgcaa agacagtcca accggtgaaa tcgttcaaga
    46321 aatgaccacg gatgaaaacg gtcatgcgga aacaccaaaa gagattgcta atgcgttgga
    46381 attgggaacc tattatgtga ccgaaactaa agctagtcat gggttcgtga atacgttcaa
    46441 acctgtaaaa gtcgaattga agtatgccaa tcaaaccgta gcccctgtta ccagtaacgt
    46501 aaaagggcaa aatcaagaag tcactggcga aaccactttg acgaaagaag acaaagatac
    46561 tggggataaa gcacaaggta aggcagtctt tgagggtgct gaatacacct tgtttactgc
    46621 taaggatgga aaagctgtta aatggagtga ggcttttaaa ccagagttag cgaagggaac
    46681 gaaaggttct gatgaaacgg tcactttgac tttagacgaa aagaaccaag ttgccgttaa
    46741 acatttagct atcaacgagt attattgcca agaaacaaaa gcgcccgaag gatatagcct
    46801 tgatgaaaca aagtatcctg tatccatcaa aaaggtggat gatagcgaaa aaaatgccgt
    46861 gattacccga aatgttacgg caaaagaaca agtgattcgc tttggctttg atttctttaa
    46921 atttgctgga tcagctgcgg gcactaccga aactggcttc aatgatctga cctttaaagt
    46981 gtcgccattg gaagggacca atgaaatcac aggtgccgaa gatgaagcga ccacagctta
    47041 taacgagcaa ttagggtttg atggttatgg caagtttgaa aatcttcctt atggggatta
    47101 tttacttgaa gaagtagaag ccccagaagg ttttcaaaag attacgccat tagaaatccg
    47161 ttctactttt aaggaaaaca aagaagactt tgtgaagagt gagtatgtct ttaccattac
    47221 cgaacaagac caaaaacaac caattaaaac ggtgaccgtt ccttacgaga agctgacgaa
    47281 caaagcattt tctgttagtt tgaaccgttt aatgctctat gatttgcctg aggaagaaga
    47341 tagtttaact tctcttgcga cttggaaaga cggaaacaaa gaattaactt ctctggattc
    47401 taccgagcta gttgataaat tgagttacaa tctacatgaa atcaaagaag actggtatgt
    47461 ggtagcgcaa gccattgatg tggatgcgac aaaagctgcc caagaaaaag atgaaaaagc
    47521 caaaccagtg gtgattgcag aaacaagcgc aacgttggcg aacaaagaga aaacaggaac
    47581 ttggaaaatt cagcataaat taaccgccga acaagtttta aataaaacta ttgtcttatt
    47641 caactatgtg tatgaaaata aggaagcttt tgaagcaggc gataagccag tagcgaagga
    47701 tgttagcttg aataaccaag cccaaactgt cagttgtaca gtggaacacc atgtttctat
    47761 ccaaacaaag gcccacctag aaaacggttc tcagaccttt actcatggtg atgtggtgga
    47821 tatgtttgat gatgtgtcga ttactcatga tgtactggat ggctcaaaag aagctttcga
    47881 aacaattctg tatgctttat taccggatgg tacaaacaaa gaaatttgga aatctggcaa
    47941 gattgattat gaagtaaatg ataaagaatt caccaaaact gtgcttgcga aaaaagtaga
    48001 taccggaaaa tatccagaag gaaccaagtt tacttttgcg gaaatcaatt acgataaaga
    48061 tgggaatatc aatggaaaac acaatgaaga tttgaaagaa aaatctcaaa ccttaacacc
    48121 aaaagaagtt ccaaccatac taagtacgcc gaaacaaccg gaaacaccaa ctgttccaag
    48181 tggctctcaa gaatctagtc ccacagtgaa gaccttccct caaaccgggg agaaaaattc
    48241 caatgtttta ctgttcattg gttttacttt gatttttgcg acggcgggct attatttctg
    48301 gaatcgccgg aactaaggtg atgagatgat acaagtaaat cctaagaacc aacgtgcgcg
    48361 accgcctcct aaaaaagtag tcgcgctatt tttgtatcca aaactaacaa tgaaaagagg
    48421 aaaagaagat ggaattgaaa tttgtcgtgc cagatatggc tgaaaccttt ggaaagttaa
    48481 gttatgccgg tgaaggagaa attataacag aaggatatgg acggaatact acggtgattg
    48541 gtcgcagtta tcatttgtat tccagtaagc aacgggccga tgatattgag gtggtagtag
    48601 ctgcggaagc cggtgaaaag gattttgatc aagaccaacc gctaaaagcc gtgaatcccc
    48661 atttggttgc caaaggctat gagattgaga atcgtgggtt tactgattac gtgttgtatg
    48721 ttgatgattt agtgaaagca taggaggaaa agaagatgag attaacagaa ggtattgtcg
    48781 tagattcagg tttaacattt gggaagttgc gtttttccgc attacgccga gaagtacgga
    48841 agcaaaatga ggatggaaca attggtaatg aggtaaaaga acgaacctat aatttaaaat
    48901 cctctgcaca agggcgaatg attcaagtta gtatcccagc taatgtaccc ttacgcgagt
    48961 ttgcttatga tgcagaggta gagttggtca atccaatcgt ggataccgtt gccaattatg
    49021 tttttcgaga aggaactacc gttaattggt tcattaaggc ggatgattta gtcttgaagc
    49081 ggcagccgaa tcaaggaaat cctacgaacc aaaatgaaag aaagaaatag gtgaagatta
    49141 tggaaattaa tgttgaacat attttagatt gtctcgatca atatggaaaa ggcgagctga
    49201 ctgaggaaca actcgttaaa gcattaacct ctgatgaaaa aatgtttctg attatacatc
    49261 aaggtttact tggagaaaat agcgacagtg aagaagactc tgatgtacta gactggttag
    49321 gagaagaaga gtctttcttt atagttgtcg aagtaaatga aaacttatgt cggcaggcag
    49381 aatccatttt ggaagaaatt ggtgtggaga tgccggatgc tattgaaggc tttttaaatc
    49441 aattggttga aacgaaacaa ctcccctcct cgtagcagta aatgactagc ataacttttt
    49501 gaaattgcct aatgaaatcc tattgggctt tttcgattgg aggtggaaac catcaaaatg
    49561 tacaaaggac atcgcatacg cgcaggagat cagcacttgg tttatcactt tgttcttggc
    49621 tggctactcg ctctgttcat cggttggatg agcgtctttt attttcaaga gtttagacaa
    49681 tttgatattt ctaagctatc actttctact attgaaatcg tttggtctat aaaagattta
    49741 gtatgtctgc ttggaagtct cgctttttca ggagctatga tattgcttta tattcacttt
    49801 tttcttgatc attggcgaag cttgtggcat cgacaaaagc tagctcggat gattctagag
    49861 aaccattggt atgaagtgaa acaaactcaa agtgaaggct ttttcaaaga tttgaatagt
    49921 agccgaacca gagagactat cagttacttc cccaaaatct gttatcgaat gaaagatgga
    49981 ttactgtcta ttcgcgttca aatttcactt gggaaatacc aagatcagct tttaaaattg
    50041 gaaaagaagt tagaaagcgg actgtattgt gagttagtag aaaaggaact caaagactcc
    50101 tatgtggagt atactttact gtatgatatg atcgccaatc gaattgggat agacgaagta
    50161 gtggcagaaa atgggactct gcgattgatg aaaaatcaag tatgggctta tgattcttta
    50221 ccccatatgt taatcgctgg tggcacgggt ggagggaaga cctatttcct cctcaccatt
    50281 atcgaagcac tattgaagtc agatgcagaa ttgtttatcc tcgatcccaa aaatgcagat
    50341 ttagctgatt taggtacggt gatgcctcat gtttattcac aaaaggaaga aatttctgct
    50401 tgtgtggaag atttctatga acgtatgatg gctcgtagca aggcaatgaa agaaatgtct
    50461 aactacaaaa caggagagaa ttatgcctat cttggacttc cacccaactt tttaatcttt
    50521 gatgaatacg tggcttatat ggagatgtta acgacgaaag aaagtgcggt gattttgaat
    50581 aagctcaaac aaatcgtgat gttgggtcgt caatctggtt tctttctgat tttggcttgc
    50641 caaaggccgg atgcgaaata tttaggagac ggaatccgcg atcaattcaa ctttcgcgtg
    50701 gctttgggtc gtatgagtga actcggatat tccatgatgt ttggggaggt cgaaaaaaac
    50761 ttctttatga agcacatcaa aggtcgaggt tatgtggata caggtggcag tgtgattagt
    50821 gagttttata cgccacttgt accaaaaggg tatgatttct tagattcaat tagtaaatta
    50881 gaaaagatga atgattgagt gatcttcaat actgacttta tacttcaagt aacgtataat
    50941 acttttatat agtaggaaga aaggggataa ttaatatgga aagtaatgat tcttatttag
    51001 agtatgcaaa agcaaataag gataagttta tttcttatat tatcaaaggg aaatcccccg
    51061 aagttggacg agacgcagtt tttatggcag ggagtcctgg ggctggaaaa tcagaggttg
    51121 ccattggatt agctgagaat tatgataacc atgtgattat tgatgcggat tactttcgca
    51181 cccagtttcc tgattataat ggaaaaaact ctagtctctt tcaaaaagca tcttcttggt
    51241 tggtagagca ggcatttaga tatgtcttag atcatggcta ttcttttatt ctggatgcaa
    51301 cttttgcaat attaagtgct gaaaaaaata tctcgcgggc gttgaaaaaa cattttcgag
    51361 tgacgatttt ctatgtttat caagacccta aaatcgcttg gaaatttaca caagaacgtg
    51421 aaattgcaga gggacgtcat gtgccgaaaa aggcatttat taacgctttt ttcaaatcaa
    51481 gagagaacat tgcaaaagta aagagtaaac atccagatgt attgcttcat atcataataa
    51541 aagattatac gaataatatt tccgaagttc attatgctac ggataatcta gaattatttt
    51601 taccactagg gtatagtagg aaagatttgg aggttcaatt acatgactga gaaagaacaa
    51661 gtaacgaaaa ttgtaaagaa atacaataag agcattgcgg atttatcgga aaatgctact
    51721 gcaaaagagt tcaaaacggt gattaaatat gtagccgatc aggccaatga aaaacaacgg
    51781 aaattagttg gattaaataa aaaatagtag gacaaattaa taatgtatga gccaagagca
    51841 aaatgttctt ggcttttttc tttgcaatga atgaggtaat gtatgagatt tttagattta
    51901 ttcgccggta ttggtggctt tcgtttaggt atggaacagg cgagccatca ttgtatcggt
    51961 ttttgtgaaa ttgataaatt tgctagacgt agttataaag caattcatga tacaagtaag
    52021 gaggtggaaa tgcatgacat cacaagtgta tcagatgagt ttattcaatc cctcggacca
    52081 gtggacatcc tttgcggcgg atttccgtgc caagcttttt caattgcggg aaagcggcaa
    52141 agattttccg atactcgagg tactttattc tttgaaatcg ctcggttcac cactcttctc
    52201 cgacctaagc ttttattcct tgagaacgtc cgaggattgc tcaatcacga aggaggggct
    52261 acgttcgaga cgatcctccg aacgctggat ggattggggt atgacgtgga gtggtaggtg
    52321 cttaactcaa aggcctacat tccccaaagc cgggagcgga tattccttat cggacattct
    52381 cgagacgcat gtaccgaaca agtatttcct atcattggac cgtcttcaac atctgatcaa
    52441 aacatcagaa atttggtaaa tatcaatcct tccaatcgag gaatgggtgg acaagtctat
    52501 ggttcagatg gcgtagcgcc aaccttaaca ggtgatgaag gaatcaaaat cgcactgcca
    52561 gcaagggatg gaatctctgt agcaggacta ttaccgggaa agtttgaaca aggtaatcga
    52621 gtttatgaag ttactggaac cgcccccacc ttgtcaacga aacaaggtgg tacaaaaatc
    52681 atgattcgaa aaaatgaaac agaatatcaa gaggtgaagc cagaagacag tgtgaatctg
    52741 gcttttccta attccacaag tcgccgaggt cgtctgggaa aacagagtgt tcatacctta
    52801 ctaacaggag accaacaagc gatcgtcacg gatcagtatc aaattcggaa gctaacacct
    52861 agagagtgtt ggcgacttca gggctttccc gattgggctt ttgatcgaga ttctcaagtc
    52921 aattcagata gtcagttgta taagcaagcc ggaaactctg taacagttcc ggtcattttt
    52981 gatattgcca gaagattaaa agagttggat gtacatggtt tatgatgagt tgattggaga
    53041 aatttattgg gtgattggaa agattcagtc agacccagaa ttagaagaac aattgcgacg
    53101 gttaaaattt gatattcgca agaatggtgt caaagtcgct ggcgatccat atttaatgaa
    53161 tgaggagacg gatgctcgaa ttgaaataaa tcaagtaatt gcagaatttg agcggattgc
    53221 ggaccaagca aaagaaccag atattcgtca atacttgtta gaaatgaaag cagagttgga
    53281 agtaaatggt attacagatg agtaacctaa accaacacaa ctgactgtta ggcgctgacc
    53341 gcggaggatt cgcgaagcag aaatcctccg tggtgctgtg cctgttcatg gacggcgtta
    53401 gccgaccatg atgtctcacc cccgtatcta acaggggggt acaaaaacac aaaaaataag
    53461 taagcaacca ttaagaatgc ttgttgtatc aaagatagta agtaatttgt ataggtgtta
    53521 actcatttga aaaagttaac accttgaatt tggaggtgag aacttggcac aacggaattt
    53581 agattatcgg ctattaaaag accgacgcaa cgaatacggc gtttcacaaa ataaattggc
    53641 tacggcttgt ggacttagtc ggccgtactt aaatcagata gaaaatggtg gcgtaaccgc
    53701 atctataaaa accatgagga aaatttttga ccaactggaa agctttaatc ccgatttgcc
    53761 tttgacgtta ctgtttgact atgtaaggat tcgctttccc acaacggatg cacgaaaaat
    53821 tattcaagaa attctccatt tgaaatttga gtatatgctc catgaagatt atgcctttta
    53881 ctcctatcaa gaacagtatg tcatgggtga tattgtggtg atgttgtctc atgaagaaga
    53941 taaaggtgtg cttttagaat taaaggggcg aggttgccga caatttgaaa cttttttact
    54001 cgctcaaaag cgtagctggt acgacttttt cgaggattgt ctaaaggccg gtggcgtgat
    54061 gaaacgcttg gacttggcaa tcaatgatcg agtggggcta ttggatatac ctgagctaac
    54121 gaaaaaatgt cagaaggaag aatgtatctc cttgtttcgt acctttaaaa gttatcgttc
    54181 cggggaactt ttaaaggctg atgaaaagga cggcatgggc aataccttat atatcggcag
    54241 tctcaagagt gaggtttatt tctgtttgta tgaaaaagac tatgaacaat atatcaagtt
    54301 agggattcca ttagaccaaa ctgagacgaa aaatcgtttt gagattcgac tgaaaaatga
    54361 ccgtgctttt catgcgattc aagatttgtt aaaaggtcgt agcattgaga gcaccacgtt
    54421 ttccattatc aatcgttact tgcgatttgc ggataaagta gaaggtaaaa ggcgaaccaa
    54481 ctggcccttg aatgaacaat gggggcgttt tattggacgg aatcggaaag agattcaatt
    54541 aacttccgag ccaaaaccgt ataccattga acgaaccttg aattggctag gccgacaagt
    54601 cgcccctacg tggaaaatgg ctaaggagtt ggatcgattg aatcggacaa cctatatcca
    54661 ggatatggta cagaatgcac gcttatcaga ccgacataaa aagattttgg agcaacaaag
    54721 tatggcaatt gaaaatttga ttatatgaaa agaggaatcg tcatgggaat tgtaaaagat
    54781 atttttttgg tatttggtgg cagtatgctt ggtgttactg tgatgtgctt gatgaatgca
    54841 agtgcagcag cggatcgagc aatggaaaag aaaggaaagt gacaagatga atttcggaca
    54901 aaattt
//
LOCUS       DAZULR010000017        54469 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.017, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000017 DAZULR010000000
VERSION     DAZULR010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 54469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54469
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.017"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(64..1485)
                     /gene="tyrP"
                     /locus_tag="ACG8ZV_001129"
     CDS             complement(64..1485)
                     /gene="tyrP"
                     /locus_tag="ACG8ZV_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070908 - tyrosine:tyramine antiporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-tyramine antiporter"
                     /protein_id="HFS4996482.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(1728..3605)
                     /gene="tdc"
                     /locus_tag="ACG8ZV_001130"
     CDS             complement(1728..3605)
                     /gene="tdc"
                     /locus_tag="ACG8ZV_001130"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HFS4996483.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(3896..5152)
                     /gene="tyrS"
                     /locus_tag="ACG8ZV_001131"
     CDS             complement(3896..5152)
                     /gene="tyrS"
                     /locus_tag="ACG8ZV_001131"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HFS4996484.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(5264..5469)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5732..7033
                     /locus_tag="ACG8ZV_001132"
     CDS             5732..7033
                     /locus_tag="ACG8ZV_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFS4996485.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(7102..7701)
                     /locus_tag="ACG8ZV_001133"
     CDS             complement(7102..7701)
                     /locus_tag="ACG8ZV_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFS4996486.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            7955..8836
                     /locus_tag="ACG8ZV_001134"
     CDS             7955..8836
                     /locus_tag="ACG8ZV_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFS4996487.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            8849..10459
                     /locus_tag="ACG8ZV_001135"
     CDS             8849..10459
                     /locus_tag="ACG8ZV_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4996488.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(10536..11195)
                     /locus_tag="ACG8ZV_001136"
     CDS             complement(10536..11195)
                     /locus_tag="ACG8ZV_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFS4996489.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(11478..12143)
                     /locus_tag="ACG8ZV_001137"
     CDS             complement(11478..12143)
                     /locus_tag="ACG8ZV_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HFS4996490.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(12290..12895)
                     /gene="dhaL"
                     /locus_tag="ACG8ZV_001138"
     CDS             complement(12290..12895)
                     /gene="dhaL"
                     /locus_tag="ACG8ZV_001138"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaL"
                     /protein_id="HFS4996491.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(12923..13933)
                     /gene="dhaK"
                     /locus_tag="ACG8ZV_001139"
     CDS             complement(12923..13933)
                     /gene="dhaK"
                     /locus_tag="ACG8ZV_001139"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004371 - glycerone kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HFS4996492.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(13908..14303)
                     /gene="dhaM"
                     /locus_tag="ACG8ZV_001140"
     CDS             complement(13908..14303)
                     /gene="dhaM"
                     /locus_tag="ACG8ZV_001140"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="HFS4996493.1"
                     /translation="MKKSILLISHSQKVTDGIKEMIEQMQKSEEVQIFSLGGINGEIG
                     SDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEEEQQQRYHLVDAPLVEGA
                     FAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            14457..14777
                     /locus_tag="ACG8ZV_001141"
     CDS             14457..14777
                     /locus_tag="ACG8ZV_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HFS4996494.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(14889..15746)
                     /locus_tag="ACG8ZV_001142"
     CDS             complement(14889..15746)
                     /locus_tag="ACG8ZV_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFS4996495.1"
                     /translation="MKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTISSSG
                     AENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELEEALE
                     AAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQQAKE
                     FNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAASFQRI
                     KDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGVLVAA
                     AYGIIRKKK"
     gene            complement(15854..17158)
                     /locus_tag="ACG8ZV_001143"
     CDS             complement(15854..17158)
                     /locus_tag="ACG8ZV_001143"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFS4996496.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVSFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(17155..17664)
                     /locus_tag="ACG8ZV_001144"
     CDS             complement(17155..17664)
                     /locus_tag="ACG8ZV_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996497.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(17839..19974)
                     /locus_tag="ACG8ZV_001145"
     CDS             complement(17839..19974)
                     /locus_tag="ACG8ZV_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HFS4996498.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(20057..21712)
                     /locus_tag="ACG8ZV_001146"
     CDS             complement(20057..21712)
                     /locus_tag="ACG8ZV_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFS4996499.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(21714..22028)
                     /locus_tag="ACG8ZV_001147"
     CDS             complement(21714..22028)
                     /locus_tag="ACG8ZV_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFS4996500.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            22198..22458
                     /locus_tag="ACG8ZV_001148"
     CDS             22198..22458
                     /locus_tag="ACG8ZV_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HFS4996501.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            22472..22786
                     /locus_tag="ACG8ZV_001149"
     CDS             22472..22786
                     /locus_tag="ACG8ZV_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HFS4996502.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(23516..24070)
                     /locus_tag="ACG8ZV_001150"
     CDS             complement(23516..24070)
                     /locus_tag="ACG8ZV_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HFS4996503.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(24196..26125)
                     /locus_tag="ACG8ZV_001151"
                     /pseudo
     CDS             complement(24196..26125)
                     /locus_tag="ACG8ZV_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(26431..27147)
                     /locus_tag="ACG8ZV_001152"
     CDS             complement(26431..27147)
                     /locus_tag="ACG8ZV_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HFS4996504.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(27148..28971)
                     /gene="glpO"
                     /locus_tag="ACG8ZV_001153"
     CDS             complement(27148..28971)
                     /gene="glpO"
                     /locus_tag="ACG8ZV_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HFS4996505.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(28985..30481)
                     /gene="glpK"
                     /locus_tag="ACG8ZV_001154"
     CDS             complement(28985..30481)
                     /gene="glpK"
                     /locus_tag="ACG8ZV_001154"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HFS4996506.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(30617..32077)
                     /locus_tag="ACG8ZV_001155"
     CDS             complement(30617..32077)
                     /locus_tag="ACG8ZV_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4996507.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(32067..33362)
                     /locus_tag="ACG8ZV_001156"
     CDS             complement(32067..33362)
                     /locus_tag="ACG8ZV_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFS4996508.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(33694..34371)
                     /locus_tag="ACG8ZV_001157"
     CDS             complement(33694..34371)
                     /locus_tag="ACG8ZV_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HFS4996509.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(34401..35492)
                     /locus_tag="ACG8ZV_001158"
     CDS             complement(34401..35492)
                     /locus_tag="ACG8ZV_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HFS4996510.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEKAYKELYLPSPLYNFLKARYQ"
     gene            complement(35593..36027)
                     /locus_tag="ACG8ZV_001159"
     CDS             complement(35593..36027)
                     /locus_tag="ACG8ZV_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFS4996511.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(36611..38068)
                     /locus_tag="ACG8ZV_001160"
     CDS             complement(36611..38068)
                     /locus_tag="ACG8ZV_001160"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFS4996512.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(38065..39960)
                     /locus_tag="ACG8ZV_001161"
     CDS             complement(38065..39960)
                     /locus_tag="ACG8ZV_001161"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFS4996513.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(40018..41793)
                     /locus_tag="ACG8ZV_001162"
     CDS             complement(40018..41793)
                     /locus_tag="ACG8ZV_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HFS4996514.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(41843..43339)
                     /locus_tag="ACG8ZV_001163"
     CDS             complement(41843..43339)
                     /locus_tag="ACG8ZV_001163"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFS4996515.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(43533..45155)
                     /locus_tag="ACG8ZV_001164"
     CDS             complement(43533..45155)
                     /locus_tag="ACG8ZV_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HFS4996516.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(45483..46796)
                     /locus_tag="ACG8ZV_001165"
     CDS             complement(45483..46796)
                     /locus_tag="ACG8ZV_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HFS4996517.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(47041..47265)
                     /locus_tag="ACG8ZV_001166"
     CDS             complement(47041..47265)
                     /locus_tag="ACG8ZV_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996518.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(47285..47707)
                     /locus_tag="ACG8ZV_001167"
     CDS             complement(47285..47707)
                     /locus_tag="ACG8ZV_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFS4996519.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(47849..48559)
                     /locus_tag="ACG8ZV_001168"
     CDS             complement(47849..48559)
                     /locus_tag="ACG8ZV_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase beta subunit-related
                     protein"
                     /protein_id="HFS4996520.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(48577..49074)
                     /locus_tag="ACG8ZV_001169"
     CDS             complement(48577..49074)
                     /locus_tag="ACG8ZV_001169"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4996521.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(49111..49563)
                     /locus_tag="ACG8ZV_001170"
     CDS             complement(49111..49563)
                     /locus_tag="ACG8ZV_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFS4996522.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(49698..50303)
                     /locus_tag="ACG8ZV_001171"
     CDS             complement(49698..50303)
                     /locus_tag="ACG8ZV_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFS4996523.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(50753..51373)
                     /locus_tag="ACG8ZV_001172"
     CDS             complement(50753..51373)
                     /locus_tag="ACG8ZV_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFS4996524.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(51375..52244)
                     /locus_tag="ACG8ZV_001173"
     CDS             complement(51375..52244)
                     /locus_tag="ACG8ZV_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HFS4996525.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(52267..52674)
                     /locus_tag="ACG8ZV_001174"
     CDS             complement(52267..52674)
                     /locus_tag="ACG8ZV_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFS4996526.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(52693..53982)
                     /locus_tag="ACG8ZV_001175"
     CDS             complement(52693..53982)
                     /locus_tag="ACG8ZV_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFS4996527.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
     gene            54040..>54469
                     /locus_tag="ACG8ZV_001176"
     CDS             54040..>54469
                     /locus_tag="ACG8ZV_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFS4996528.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRA"
BASE COUNT        15478 a        11503 c         9363 g        18125 t
ORIGIN      
        1 tattcacttg gcaggacctc ctactaaatc agcgacaaaa cgtcggctga aagacttatt
       61 tttttatttt tcttctaaac ttttttctac ctcaatcccc caagaatctt tcttgaagtg
      121 attgatgatc aatggaataa cgaacatgac cactgtgata gctgctacta ataatgcatc
      181 actcaatgtc gctgtaccta atgtagcaaa tacgacaacg atgatagaga agatcagcat
      241 gcagctgact acccaagcta atccgtttcc gtttttacca attcggtaag gacgttcgaa
      301 ttctggatgt ttcttacgca ttttaagcaa tgaaacagca atcaaaatgt acacgataca
      361 ataaataaca gttgtagcat ttgtaagtgt caagaataca gcacttacgt catccattac
      421 accataaagc aaagcaaata atgaaataac gattgattgt gttagaacga catttctaga
      481 tacgccgtat ttgttttctt tatggaatcc gaattttggt ggaaggaatc cttcacgagc
      541 tacttggatg attgtttttg atggtccagt aacccaagct gataattgta aaagcacacc
      601 aataaatacc atgaagctga agatatttcc gatcacttct ggtaagccta ggatttgaca
      661 gtcaatcaag ataggctgcg tgatatttgc taattccatt tttccatctg gtacgacatt
      721 tgctacaagc atcgcattga tgacattcaa taaaactaat ccgatcaaag cgataaatac
      781 gccttttgta taattttttg ttgcgtcttt caaacgaggc atgtaaacag aactcatttc
      841 gatcccaaca aaaataaatg tgataccagc taagtatttc aatgaatcaa tatgttccaa
      901 gtcagggaaa gcttttgacc atgaaaagtc acctagatag ccgtttgaga ctagtccgac
      961 tttgaaggct gccaaaacac ctaaaacgaa catgatgact actgggatat atacccctag
     1021 ccatacaccg atgttcccgc cgacttttgc catatcgaat ttcaagttca agatcgtgat
     1081 gatccagtag ataactaaaa tacaacctaa aacgaaccag tgattattgc caagttctac
     1141 attaccaaat gtgtttccta acaatggtcc taaagtagaa gcgaccatta ccatacctgg
     1201 gaacatttgc acccataata gccatgcaac gacaaatccc catttgctgc ccagtgctgt
     1261 ttttacccat aactgaggac cgccttcttg aggaagcatc gtggaaagct caccggaaac
     1321 cattgatatc ggaccggcaa aaaacaaaac tgcaaaaatt gaataaaaaa tcaatgtcca
     1381 accgactgcg gctaacgtag gaatactccg aaccgttgca cacagtgcca ttgtcagacc
     1441 gataaaggtc ccaagaccca ttttacttac ttcagattta ctcaccgttg acactctcct
     1501 tgattttttg gataaaataa cggtgtcttt gaagtagttt cagcaataaa cgaaacaatt
     1561 cagcgaatat ttgaggggat tctttgagtt tattgcttga agggtttctt caaagacaac
     1621 ctcaaaacaa agggatcgaa gagcttaggt ctccccttgc tcttcagatc caaacatgcg
     1681 tcagaaacag ttagtattca agctgttttc taacatgatt accttgctta ttttgcttcg
     1741 cttgccaata attggtctgc gtagattttt tccaattttt cttgaagagc tgctttgatt
     1801 ttttcagcat attcttcaaa gtgttcttct ttgttcatgt atggtgtcat tacgctggca
     1861 cgcaatacag ttacttttcc ggcacggttc cattcttcat ctgagaatcc tagttggttc
     1921 acaaattgta atgggctgtt gccatagtct gggatagcaa agtcagtatg tgaagttaag
     1981 aactcattac cgtaaatgct tcctttcacg tatgaagaat aatcatatac gtcatggttc
     2041 aatttattca ttgcaactaa gtcatcgttg cctttttctt tgaatacata gtctaccata
     2101 ttgaaatctg gataagttaa tggatgaact tcgatttctt tgtctcctac tttaaatgac
     2161 aagtcattca agaagttgta gaaacgatgt gcaccttcga ttgatgcacc cattaattta
     2221 ccatatcctg tgacattcaa aggtaagaca tggtgtgctg cccaaacgct ggctgctgtt
     2281 gcccctgctt ttgaaccttc caagatataa gccccaagta atgctgggat atctgcgcct
     2341 ttttcaaata catatgtcgc aaagtaagag ataacgtctc tcatgcggat atctttgatg
     2401 acgataccac cggcagaata tggaacatag cccattttat gtgggtcaat cgttacagat
     2461 tctgcttctt cgattgcttt atatgcactg tgtacttctt ctaagatata atctttgttt
     2521 tctgtaaaga cattgtattt gtaatgaaca tcttttaaat cttcaaatgg aatgaagttg
     2581 ttgtcttcgt ctaagaaaat cgcacggccg tatccgccat aagcagcatc tacgtgtaag
     2641 tagaagtaaa taccgtcttt ttctaatacg cgacgcaatg caacgatttt atcgataccg
     2701 tcgattgctc cttcttctgt tgatcctaca acaccgacta cacctaggat tggtgttttt
     2761 tcagctgcta gaccacgaac gattttttca agttcgttga tgtccatgcg atagttgtgg
     2821 tcaactggca ctggaatcac ttggtctaaa ccgataccga tgatgtcggc agcttttagc
     2881 catgaatagt gtttagtttg tggaaccaac cattttccta atttttctaa atgttttccg
     2941 ctacgtgctg agtgagcttt gatttcgtcg attttttctg ggacgctgtc taacagattc
     3001 atgatttctt ctgttgacaa gttcattaat tcccaatcgc tttttccagc aactagttca
     3061 ggtgtcactt ctttcattgc aagcggcaat gatttgatgt tgcgggcata ccaaagtcct
     3121 tctaagtttg ctaaagaacc atcagcaacg atgtggcccc agccatcttt atagctcatt
     3181 aattttgcaa attccattcc tacttcttct tccatttggc ttgttgcagg agaagattca
     3241 taggcaacgt tattaccatt ccatagcata gcaaaattgt acgctagtaa agatggcatc
     3301 aatgtttcag agttcatatg accccagtaa cgtccggcat tatgccaagg aacggaatgg
     3361 gtacgcatcc gcgctgaaat ttctgataga acatcctttg ttttattcac agtgtgttca
     3421 aaactagcac tgcttttttc ttctggcgta ataataggca tgtcttgagg catgtagttt
     3481 tgacgccagc ctaaatgttc atccaccaat tcattcaaca aagctttata gatttggccg
     3541 ttctcagctt tgtccccaat gaatagggca tttaggttta gatctttcga caatgattca
     3601 ctcatagtga aaccctccta aaaaaatatt taaattttgt cgagccctac attacacctg
     3661 ttcttctatt ctgtaaacta agttttggcc tgatttttaa tcatatttta atatgtatca
     3721 attatccgaa ttgttcacac ttttgaaata attaaaaaaa acgagggaat ttacaaatgt
     3781 aaactccctc gcaaagattg tattaacgac aaccagcgtt ctattttagg atgggtttca
     3841 aaattggaat gttgtaatag tatttccctt tttcaaggta aaaacttact aaattctaat
     3901 caattacttt ggccaaaaag taatttttct taccttttcg aataaccaca aacttaccat
     3961 cgaattcatc ggatggattt atgacaaaat ttaaatcggt aacgcggtca ccgttaatac
     4021 ttatagctcc gtttgaaaca tcttcacgtg cttgacgttt agatggttca atttttgtgg
     4081 aaacaagcag ttccacgata ttttcaggtg tgcttgaaat ttcaacgttc ggcattttac
     4141 cgaatccttg cgcgatttct tccgcattta gttctttaat atttccagag aacaatgctt
     4201 gcgttatttt ttgcgcttct ttcaagtctt cttcactatg cacaaatctt gtaacttctt
     4261 ctgccaaacg gcgttgtgct tcacgtttct caggttctgt ctctactttt ttcgctaagt
     4321 cttcgatttc ttcttgagac aagaaagtaa agaatttcaa gtatttcact acatcgcgat
     4381 catcttgatt caaccagaat tggtagaact caaatggtga agttttcttc ggatcaagcc
     4441 aaacggcacc gcctgcagtt tttccgaatt tcgttccgtc agccttcagc atcaatggga
     4501 tcgttaaacc gaacgcttct gcttctggtc cttctaattt tcggattagg tctaatccag
     4561 ctgtgatatt tccccattgg tctgctccac cgatttgcaa ttgcacatcg tatgttttat
     4621 gcagatgcaa aaagtcgata gattgcagga tttggtaagt aaactctgta aatgagattc
     4681 ctacttccaa acggctggca acgatatctt ttgctaacat cgtgttgatg ttgaagtttt
     4741 taccgtagtc tctcaaaaat tcaagtaaag agatttttga caaccagtcg tagttgttca
     4801 caaatgtgat atttgcatct ttaccaaaca attttctcat ttgattggaa agtgcgtcca
     4861 cgttatgttg cacttgttcc atcgtttgca acacacgttc tgttttgcgg ccgcttgggt
     4921 cgccgatcgt tcctgttccg ccgccaatca gaatatatgg atgatggcct gccaattgga
     4981 atcttttcat catcataaat ggaatcaaat gtccgatatg catcgaatca ccagttggat
     5041 caacgccgca ataaagtgaa atgctctttt cttcaacgag ctcgcgaagt ctttcttcgt
     5101 ttgtttgctg attaatggcg tcgcgccaag ttaattcatc aataatattc attttactga
     5161 cctccgtgta gtttttttat gaaagcagga acctgctagc atatgtaatt aattatttct
     5221 tcaggatagg ataggaaata aaaaaagtcc cttggcatat aagccaaggg acgaaatctc
     5281 gcggtaccac ccaatttgta tgtctagata tccaacatac ctctcgaaca tttaacgctg
     5341 tcgcgtggca atcactgcca aagactcctg aaatgtaatt cgctttaaag catgtactgg
     5401 tttgcagcga ccaccagctt tctgaaacat tggctttaac aactacttcg tttcgatctt
     5461 cgtcttgtta ttattaatat gtgtctatca tagagcgcaa ctttttcttt gtcaacagaa
     5521 aaaggatatt ttttttaaat tcctcatttt ttcttttttg aatccgctct aattccgaac
     5581 attttatttt caattattgt taaaagaaat aactttttct gtattttttc tgcaatttat
     5641 cgagaagtca ctttactttg cctcttattc tttcttcgtt acaataagga atgggacaag
     5701 taaaaaaatg aaaaagcaag ggacgaggta tatggaaaaa aagcaaaaaa ttattttagg
     5761 agccacttct gctttaacta tcgttatttt aattctaagt ttgttttttg tcatccgatc
     5821 atctacaaaa aaagaaccaa tcattcctga aaaaaaaata acagaaaaag caaaagaacc
     5881 gacagatgat aagcaacaac tagttactca agcaaaaaat ctggctcaaa gctacgatta
     5941 tgaccaagcg attgcgttat tggaaaaaga tagtaagaac ggatctactg aaacacaaca
     6001 gcttcttcaa acactaaaaa aggagaaaga acaactgatc gactggtctg atcctactca
     6061 gatctctcat gtctttttcc acagcttgat cgtggacccg caaaaagcct tccactctca
     6121 acaggcacaa ggatacaaag attatatggt gactgttgaa gaattcaacc gttcgatcga
     6181 acaactttat caaaatgatt ttgttttagt taatttgaat gatttgatcc aaaaagacga
     6241 acaaggaaat ctttccttta acgggcttgc gctacctgaa ggaaaaaaac cattggttct
     6301 ttcacaagat gatgtcagct attatgaata tatggataat tccggttttc ctagccgatt
     6361 ggtcgtatca aataacaatg aaatcaaaaa tgtctataaa gagaaagata aagaagaaat
     6421 cggtgacttt gacatggttc ctctgatcga tgcctttgtc aagaaacatc ctgatttttc
     6481 ttatcgaggc gcaaaaggta ccttggccct gacaggttac aacggagttt taggttatcg
     6541 aacatcaaaa tctcaatatg gagacaatga aaaaacaaaa aaagagatta aagaagctaa
     6601 aaaagtggcg gaacagttga agaaagacgg ctggagcttt gcttcccata catggggtca
     6661 cttgaatatg actcaagctt cactagaaga tgtaaaaaaa gacaatgaat tgtggcagca
     6721 agaagttgca cctatcctag gaaaaacaaa tattctgatt tatccatttg gtgcagacat
     6781 cagcgactgg cagccttatt cagcagaaaa tcaaaaattt gcttacttga agagtcaagg
     6841 tttcgatatt ttctgtaatg tcgatgcttc tacaccagct tggggacaat taggtacgga
     6901 tttctatcga aatgctcgga tcaatatcga tggcattcgt tttcaatctg atttagacgg
     6961 aaaaaatcct attcttgatc cattcatcaa tgtccatgat gtctatgaca aagaagcacg
     7021 cgaatctgct tgattttacg tcatttatga accaaaaaag ccgaactgac attttatcgt
     7081 cagtttcggc ttttttatgc tttatttctt cttcggtgcg attcccttga tcaggacttc
     7141 tgtccattct gctgtatatg gaagcagttt tgcgtatatc tccggcttag aaattccttc
     7201 taccattgct tgaaaataga ggatcaagaa ctcatccgaa tatttcaaat ccacttttcc
     7261 ttctttccgc cctcgatgga aaagatcaag catgatactg aaactttctt gcgtatacgc
     7321 atccatcgcg tcagaaaatt cttttttttc tttttttgta tagtatgtca tcaaatcgat
     7381 ataaaattgt ttgttcactc gattgagata acggattttg ttttcactca tggcaatcag
     7441 tgtttcttca aatggaagat tttccgcaat caacgctttc gcttcttgcc ctaaatcatt
     7501 cataaatgca aaaaatactt cataaatcag cccttccttg ctgccaaaat atttaaaaat
     7561 cgtcgcttta cttacctgag cgttctcagc taccttatcc attgtcactc cagcggttcc
     7621 tatgtctgtg ttcatcaagt caaaagctgc ttgtaaaatc tctttctttt tctcttgtgc
     7681 tctcttttca aaaccgttca tttgtagagc ctcccgtaat tttaaacttt tataatatat
     7741 atagttcaaa tttattctga ggtttattat aactatctat tgagaaagta tcaagctagc
     7801 aattccttgt ttatgaattc attgacagaa atttataaaa agaatattat gtactaaaat
     7861 aataaaaaaa gttttataaa aaggtataaa acctttttat taaactattt aatcttgttt
     7921 agtatatatt tttagaaaaa ggagtggggt ttttatggca gaaatcgtca aagtcacaca
     7981 tttgaaaaag agctttggtc gtttcgaagc tttaaaagat gtctctttca ccgtacattc
     8041 aggtgaagtc gttggattta tcggaccaaa tggttctgga aaatccacga cgattcggac
     8101 acttttaggg attataaaaa aagacggcgg aacggcaacg atttttgggc aagatgtatg
     8161 ggaagatagt ttatctatcc atgaacgtct ttcttatgtt ccaggcgata tctctttgtg
     8221 gggaaatttg actggaggag cgatcatcga tctcttcatg aagcttcatg gaaaagggag
     8281 tgctcaaaaa aaagatgaac tgattcaacg tttctctctt gatcctaaga aaaaagcaaa
     8341 aaactattca aaaggaaatc gccaaaaagt gggcttgatt gctgctttgg ctgttgattc
     8401 ggatctctat ttatttgatg agcctacttc tggtttagat cctttgatgg aaacgatttt
     8461 ccaagaagaa gttgaaaaat tgaaagaaca gggcaaatcc atcctacttt cttctcatat
     8521 tctcagtgaa gtcgagcgac tagcggataa agtcgtgatc atacgcgaag gaacactcga
     8581 tgaagaagga acactcgatg aattgcgtca tttgactcgt tcgaccatca ctatagaaac
     8641 agaagcagag aatagtcact tagcacaatt gaacggtgtc catgactttg tgcaaaaagg
     8701 tcacctcgct caatttgctg ctgataacga agctttcgat gtgattttag ctgaagcgtc
     8761 caaattaggt gtgaaaaaat ttgaatctat tccaccgact cttgaggatt tattcatgag
     8821 acattatgaa ggatgaggag gaagcgaaat gactgataaa ttttcacgct ggtccaccct
     8881 tttttctcaa aaccttagcc gtgactggaa aaagatcctg atatggctag tcggtgtcac
     8941 tgctttttct ggtggttttg tccctgcgtt tgaagaattg acttccggac aaggattagc
     9001 tggattatac gaaaccttgc aaaacccggc aatgattgca atggtcggac caactccagc
     9061 ttcgaatgct gctgagtata ctttaggagc gatgtatgca aatgaaatgt tgcttttttg
     9121 cagtttgttt gctgctgtga tctctgtttt acacgtggtg agccaaacga gaaaaaaaga
     9181 agaacttggt ctgattgaac ttattcgttc ctttcgagtc ggacgtcaag caaactcttt
     9241 agctgtcatc gctgaaagta ttctgatcaa tttgctttta gcaatatcga tcagctgtac
     9301 gatgattttt ttccaagcgg attcgatcac tgcagaaggt gcttggcttt ttgggctatc
     9361 tgtaggtagt atggggattt tggggagtgc cgttgcactg tttgctgcac aactgatgcc
     9421 aagttcagcc agttcgaatg gtctgtcttt agcgttttta ggtggacttt accttctacg
     9481 agcaataaca gatgtagctg attcctccct ttcgatgtgg aatcctttag gctggtctta
     9541 tttgacctat ccatttacaa ctaacaactg gattcctttg ctttatttgt ttttgttcag
     9601 tctaatcttg ataatcagtt catttgtttt agaggaacat cgagatttga acaccggcta
     9661 tatccccgaa cgtgaaggaa aaccgtatgc taaacgttct cttttatcct tgcgtggttt
     9721 attattctat ctaaataaag ggatgacaat cagttggctt atcacttttg gtttgatggg
     9781 ggcggcatac ggctctatct acgggaatat gcaacagttt ttagaaagta acgacttaat
     9841 gaaacagatg tttatccaat ctggcgtctc aattgaaaaa aactttacaa gcacgatcat
     9901 ggtagtcttg atttgtctag ctgctatttt accaattgct agcatcaatc gtttatttac
     9961 agaagaaacc cacggacgta tgaatcagct gttcgcaaca aaaatttcta ggaaccaact
    10021 ttattggacc aatatgttac tagctattct atttgctata ttggcaatcc tgattagttc
    10081 tggtgcacta gggctttctg ctttggcttc gatgaaggat gcgaaagaca tggatctatt
    10141 gatgtttctt aaagccgggt tcaatttcct gcctgccgtt ttagtgttta tcggaattag
    10201 tggctttcta ttcggatggc ttcctcgaat cggtaaactt gcttatatct acttagctta
    10261 ctcctttgca ctcaattact ttggcggaat tttggattta ccagaatggt tttccaaaac
    10321 agctgtccct agctgggttc cacggatgcc aaacgattct tttgatcttt ccgtgttcct
    10381 tacgttatca tgtatcagcc ttgcactgtt cgtccttggt tctattggtt ataggcgaag
    10441 agacttacta gaaggataat aaaaaagcat gtacaatttc atgctagcct ccaaatctgg
    10501 gtcaaaaatc caacatttgg aggtcatttt tttatttaca agtcttctaa ctgctcttta
    10561 tcaatgatcc agacttctcg attctttctt tttacataac cattctcctc taataattta
    10621 aattttctag ataaagtttc gggggtcgta ccgataaatg cagcaagttc tttcattttc
    10681 attggcagga aaaagtgatc cttccctgtc gctttagcta agtcaagcag atagacagcg
    10741 actcgttctt ctactttttc catcatcaaa aaagttgtct gctgctgtac ttttgttaat
    10801 ttctcaacgt tgattgctaa aagtttcaga ctaagggcgg gataatgcag taagagttcc
    10861 gagaaatctt tttgtctcaa tatgcaaatt tccgtttttt ctagtgcttc gccaaataaa
    10921 gactcatttg gaacgcctag caactggctc tctccctcat atccgcccgg ctctattact
    10981 cgtaaaagct gttcctttcc gctagcagat aattgataca ctttcatact gccggaggcc
    11041 acgatcacta attgaggttc tccattcggc gcaagaatct gttctccttt ttccacatag
    11101 tgatgtttga caagtgcgtg tactttttct tgatcttgct gtactaagtg attgaacaaa
    11161 ggaacaaatg aaacacataa atgatcatga ctcataatct ctcctccttc taaacagcta
    11221 tttctaataa agaaacataa cttcccttat tccaactgat aattttcttt tatcatagca
    11281 taaacgtcaa gcgaaccaga taccagcaaa tagagtggat ttctttttgt cccttgcttt
    11341 attttccttc ttttgagacc ttaagtaatt gattcctatc aattttttaa atatttactt
    11401 tttgaataat caaaaacaaa ccttcactcg caagccgaga gtaaggtttg tttttcgcat
    11461 tgcttatttc gtgttgtcta ttgaaatttt tccgcaccta gcttttgata tagtggtgct
    11521 agttcttgta aggtttcagc ggttatttgc tcaacgtgtt cgatttcttg cggatagaag
    11581 aatagtttac ccatttgaaa ggttcggtct ctcatcgctt ttttcaactc ttcttgtttc
    11641 tttgtatcgg acaaatagtc agacaaagct aagtggtcgt caagttcatg ttctggttgc
    11701 ggccatatgt aataatcctt gatatcgact gttttgctcc actctttcag tatcgcaagc
    11761 aactggttat acgctgcaat gctaccatat cgttcttcgc ttttataatg ttggtacatc
    11821 aaatagattt ggtattgttt ttgattcaac aaaactgcta gacaggcatt ctcgtcttga
    11881 cgagattcgc ttcggtacgc gctccaaaaa tgactgcgta aattccagcc attcgtccag
    11941 ctttcgattt taggtttgct catgccgtac atatcaggca aaagtgcagc tgtctggagc
    12001 tgaatctctt tccatttttg ccagtgttct ttatattctt tcttgatttg ttcaatctta
    12061 tctgttggat ggctctcttt gagctgtttg aatgcgtaga ttggtcgatc aaacaactga
    12121 taatctgatt ttccaagttc cattgtttcg cctctttccg ttatcttttg tattctacct
    12181 gaattttgcg atatggacaa atagaggttg tgaaaaagct gttctgcatc aagtcataag
    12241 aacagccaaa caaaaaactg cgatgagcat caccgcagtt ttattgaact taaggttgat
    12301 tgatcacatc taaaagcgtt gaaaataaaa tggcactaga agcagctcct gggtcgatat
    12361 gtccgattgc acgctctcct agataggaag ctcgtccttt tttagctacc aagactttgg
    12421 tgtgttcttt tgcctggtca atgatttctt ttgttaaatt ccctgccttc aatgcctctg
    12481 tgactggcag ccaaacatct aacatcgttt tatcgtcagc ttctgccttt cctcggcttt
    12541 gaatacccgc tgttccctgc tcgatcactt cgcctaattt ttcttgagaa tcaatagaat
    12601 cgacctcttt tgtcgctttc atcatgttca tgaatgcaga tccgtataac ggaccagaag
    12661 ccccaccgac tttcgatatc atcgccatag agaatacttt gaatgtatcg ctgattgttt
    12721 caggatgatc ggcttgaaaa gcttcttcat aagctgaaac ccctcttccc atgttatttc
    12781 catggtctcc atcgccaatc ggggtatcta gatcactgag atattgtttg ttctgattga
    12841 ttgcctctgc aaattgcgtg agccattctt ggatttcttg aacggttagt ttcatattat
    12901 caccctttta tcttgagatt ttttaccatg aaatcgtctg tacattgctt tctaaagaat
    12961 ctttccattg tgtctccgtc aagtcgatca gtgttagaga aagaccttgc atatctagtg
    13021 aggtcataaa attaccgact tttcggaaaa ctacattgac gcctctttct tccaacagag
    13081 ctaaaacatc attcatgaac acgaactgtt ccatcaaagg cgtcccgccc attccgttga
    13141 ctagtacacc tgcttctttt ggtaaattcg agtaatcatc taaaatctta gtaacaagtt
    13201 cctttgccag tactttagaa ggctgcatct tttctcgacg atagcctggc tcaccgtgga
    13261 taccaacacc atactcgatc tcatcttctc ctagttcgaa tcctggtttc cctacttctg
    13321 gtacagttgc tgctcgaagc gctagaccga tcgtcttagt tgcctgtacg accttttctc
    13381 ccagttcttt caactcagct agggaagcac cgtttcttgc tgcatcgccc acgattttgt
    13441 gtacaaggac agtacctgca actccgcgtt ttccagcagt atacgtacta ttttcaacgg
    13501 cgatatcatc atctacgatc acactttcta cttcaatatc gtccatagca gctaattcct
    13561 ttgccatatc gaagttcaat gcatcccctg tataattctt aacgatcagc aaaactcctt
    13621 ttccactatc ggcttcctta atagccgtct gaatctgatc tggagttgga gaagtaaaca
    13681 catcaccaag caccgctgca cttaacatcc cttcccctac aaacccggca tgggatggtt
    13741 catgtccgct tcctccacca gaaaccaaac caacttgttc cgctttctga ttcttggcta
    13801 caacacggga agattctaca cgatgaacaa gttctggata gctttttact aatccttcca
    13861 gcatttcttc gacaatattg cttggatcat tcatgatttt tttcaattta ttcccatcct
    13921 ttctttccgg cattttgtgc ttctgttaag atttgctgag tatcatctgt tataccggca
    13981 gtgatggctg ctgcaaaagc tccttccact aaaggcgcat ccaccagatg ataacgttgc
    14041 tgctgctctt cttccaacat gtcttttgcc agttccgagt tcaataccgc gctaccgata
    14101 tccgcaaaaa caaaataact agctgcatcg cttgattcat tgactgcttc tacgattttc
    14161 atcgggtctg atccgatctc gccatttatt ccgccgagag aaaaaatttg cacctcttcg
    14221 gatttttgca tctgctcaat catttcttta ataccatctg ttactttttg actatgagaa
    14281 ataagcaaaa tacttttttt cacaagaatc ttcctttctt ttacatagtt gctaacgatt
    14341 ggtttcgctt tcattaatga acaattcaag tatataataa atttctaatt ttgggaaaat
    14401 atgtgtagtg cttcttgaag tttgttatac tttaattaaa agagaggagt gatcgaatga
    14461 ttacaacaac aacgaacagt gtagagggaa aagccgtagt agcttataaa gggatcgttt
    14521 ttggtgaggt cattactggg atccatgcat ttaaagactt ggaggcgggg ttgcgaaata
    14581 tctttggcgg ccgctcaaaa agctatgaaa acgaactaat gggtgcaaga gaagaagcac
    14641 ttgccgaaat ggccgaacgt gcaaaagcat taggagctga tgcgatcatt ggcgtaaaaa
    14701 tggactatga agtattaggc agcgacaatg gcatgctgat ggtcacatgt agtggaacag
    14761 ctgtctccac gagataagta ggggacatct gttttaataa ctaaagagag atgggacatg
    14821 tagtggcact caagaattag atttttcagt ctaacttcga ggtactctac cttcccatcc
    14881 tctctttttt atttcttttt gcggatgatt ccgtaagctg ctgcgactaa cacacccgcc
    14941 cctgctaagg aataactgac agaagctgtt ttttcatttg tttttggcaa agtctgactt
    15001 gttgatttgg atggctctgt cgtttgctga actgtttctg tcgtgcttcc agaggtcact
    15061 gatttttctc ctgccgaatg caaaatatct tttattcgtt ggaaactagc tgctaagtca
    15121 gctttttttg cttcaaaatc attagcaact gtttgtgctt cgctgatctt tccgtggatt
    15181 gcttgactgg ccgctgtgat atccgcttga gtttgactta gctttccaga agctgtttga
    15241 gcaacctgat ttaattgctg attgaattct tttgcttgtt ggatcttccc gtcaagatct
    15301 gtttggacag cttccgcttt tgctttcgct tcggcaagct ttttctcaag ttgtgcacgg
    15361 tcatttccca ctttattttt aagatcagct aaatcttgat cgattgctgc ttggtcttct
    15421 ttcaatttgt tttttgcagc ttctaatgct tcttcgagtt cttttctttt attttccaag
    15481 tcttgcaaat gatcgatttg gtcagaagag gtagaactat ttattgatgt atcttctgaa
    15541 gatgaaatcg tttctcctga attatctgtc ggtacattgg aagtcatttc tgtttccgag
    15601 gcaccgtttt cagcaccaga agagcttatg gttgttgaag gttctgtttg agcaggttca
    15661 gaagtttccg caaaagctgt ctgtcccaat aagaaaatac tggaaacagc aattggccag
    15721 attaacggct tcattctttt tttcatcact tttcccatcc ttactacttt ttaactaatt
    15781 tcttattata agcaaaaatg tttggaagaa ccataaacac aacaggctgt ttgtctaaaa
    15841 aacggtgcat cttttatttt tttgtacgtt ccgggctttt ccatgtcccg cttccataac
    15901 ctaaaatcgt tttgactgct ggaatgaaag tcgtcacgat cgttatcgcg ttcactatcc
    15961 agaacaaaag catatatagt ggtgcgaaaa gaaggtattt caattttctt cgtcgatcat
    16021 ctacaatcag cgaagctagc aactggaaaa atcctgcgac catttcaaag cagatgaaca
    16081 caaaactgaa tgtaaaagta atataaatct gttcgtagtt tccttgatat acataatgcc
    16141 cgattaatcc agcaaaaaga actacggaaa tacaaaagaa tattgaccag acaatactca
    16201 atgtttgatc aatgaagatg atcgttcttc caatatgttt aaaaggatgg agcatcactt
    16261 ttttgaaatt cgtcagccag acttctgttc caccttttgc ccaacgtttt ctgtgtcgat
    16321 atagcatctt caacgtcaca ggtacttcca tgaaaaagat aatctcagga gcaaaaacag
    16381 ataaccagtc atttaactga tgatcccaag caatactgat gtcttctgtc gctcgatctt
    16441 gtctgaatcc gcccacatcg atcaaggctt cttttcgata catcgtattt gctccactgt
    16501 acgcataaag accaccgaaa acagctgact gtgttcgttt aatgatgccc acgatacttg
    16561 agaattcaac cgtttgagat tttgcaatca atttggtacg attttggaca tccatatttg
    16621 cagtgaccgc agcaatatgt cttgcaccag ggcgaatgaa ataattcaca tacctaatca
    16681 gtgcatctgg ctccggtacc gtgtctgcat cattgcttaa aatcaatttc ccttttgcaa
    16741 aggcaagtcc gatattaaac gcgtgggctt ttcctttatt tttttcgatc cgaaccacac
    16801 gaagattagc gtattttttc atcagtctag ctaatatttc tggtgtttgg tccgttgaac
    16861 catcgtctgt cactaatacc tcatagttgt gataattcaa tttcgtcatc aaatactcga
    16921 ttgtatattc gatcacaatt tcttcattat gggctggcac catgatcgtg atgaacggtt
    16981 cgacactcaa gggaacatct acccattctt tttgcttatg tttgtataaa aacacataac
    17041 accagacacc aataaacgat acaaatccgc ctaaaatcgg ataagaaacg agaaaaaaat
    17101 acataataga caaacaagta tctaagaata aattacctgt atgggtgatt gagatcattt
    17161 cagttccacc ccattttctt tatacaaatc tgcaatgaat gtcgtatcta gatttttctc
    17221 ttcggagaca gaataaaaac ggaccgtttc tctctcttct tttgttccaa aacgttccgt
    17281 atacacttct tcaagtaatt cttgtctttt tttcaatttt tcatcttcat attcaaaaga
    17341 tttatttact tttttgtata gatttcgatt gttccaccta gtcaatacaa atgaggtaat
    17401 caggaaactg aaaaaaatca atacaaaaaa gccgattaag aaatacagca ttttcttttc
    17461 tgataaaaaa gcgtacaagg aaaaatcctt ggctctttct ggtctcgtta atgggaaaaa
    17521 gacccatata aaaggaagaa caacgatcat ccatcctaaa agagccacta acgtttgcca
    17581 aatctttaac cagtaattac cttttgaaaa atacttatct ttcaccaaaa ttgatgcaac
    17641 ttcttctctt gttacttttt tcatatcctc acctcacgtt tttttgttac gacgtaggag
    17701 tttaccatac atttcatttc ttttcacata aagtgttcct aaatttttcc taagaaaaag
    17761 aacaaaacat ttctcatcag caaatgaaaa atattttgtt ctttttatca gttgttcttt
    17821 ttatttttta tctcttaatt atgttgctct ttccaatacg acaatgcttt tcattcctct
    17881 agatatcgcc gtgtacattt gtctgcgtct tctttgctca tctccatcgt tttcaaatgg
    17941 atataagatt acatgatcaa attccagtcc ttttgctaga ctcaaaggaa tgatttggca
    18001 gttttctaat ccatatgaat tttttttaat cgattcttgt agcgtttggg tttcctcttc
    18061 tgtttgggtg ataactgccg ctttttctcc ttttagagaa accaaaatct cagctagtat
    18121 tttcaacaat tcttcagagg atcgaaaaga gcggtattcg ggttcttttc cttgcggtcg
    18181 gatcgatacg atgtcgatct tctcttgatc cacagcatag gttttgaaaa gctctgtgat
    18241 tgctccgcta gaacggtaac tatttctaag atcataccga tggatcggca gatggtagtc
    18301 gtcgaaacaa cgcataatat cagcaaaagt agtggaagaa ttaaagattg cctgattctc
    18361 gtcacctact aaagtaaagt gagtttttgg aaataattcg atcaatagac ctaattgtgc
    18421 cagggtataa tcttgtactt catcaatcaa tagatagcga aatgctggta catttacctt
    18481 ttcaacaagt aaatgacgaa tagctaatat aatgactgct tcatcaacag tacgtgtggg
    18541 ttgccaagca taagctgagc catatcgttt ttcataaatt ctttcaaaca actgatgctc
    18601 atccacccat gccatttctt cgatttgtct ggttattttt cgatattttt tttgtaaaag
    18661 tttccttgca taagctacaa tactttgttc cgaatcatca gaaatcaatt taccgaataa
    18721 ttccaactgc ctatcttctg tcaacgagag tacctgattc tgcacagcag gactttttgc
    18781 ttgtttcaaa agatgattct tccattcgct catcagtgcc tttttcgttg cttgaagcct
    18841 atcgatcaat ttaggatgag caggaacttt ctcatatatt ttttcgatcg tttttttaga
    18901 aaggactgtt tttccatttt tagtaagtcc acggataaaa ttcggatgat ctaaaaacaa
    18961 aggatctgat tgttttagat tatcgataaa ctttttgcta cgcaaacgtt ctgtctgctc
    19021 cgatacattt tctcccgtga tacgtttgaa ataagcctct tcaccttcta tttcctctgc
    19081 tgaaagctgt gaaaccagct gtatgatggt tagattcagt ggatttcttt cacctaatga
    19141 tggtaggaca ttcgaaatat agtcgataaa ccgatgatta ggtgatagaa tcagcaagtc
    19201 atcggatgtc atcgtatctc gatataaata gagcagatac gcaatacgct gcatgatagc
    19261 agaggtttta ccacttcctg ctacgccatt taccaagata ttttgacttt tcacatcccg
    19321 aatgattgtg ttttgttccg attggatcgt agcagtgata gccttcattt cattggtctc
    19381 atcttggcct aagacttcta ataatacgtc atcttgaata gctacagacg tatcaaaaaa
    19441 cttgaccaaa cgatctcttt ccaaaagaaa ttgtcgtctt tctttaataa ccgtatcgat
    19501 tttattttga cgaaccgtat aagaagatgg accaatcatg ttattgtaaa aaagttcggc
    19561 aattggtgaa cgccaatcat aaacaagatt ttcatctgca tcatctgtga aatttgctgt
    19621 accgatataa aaggattctt ttggctcatt atccagaaag tctacaacga cttttccaaa
    19681 gtagggactt ttcaataaac gttcgatctt tgctagctga ttttctgcgt ttttctgttt
    19741 gatattcatc tgatcgattt ctctattttt catttcaatc atcgaaaaag tatccaggtt
    19801 atctaagtaa ctgtcaaaat tcaatcgaag ctcgccagcc atttctttca acgactggtt
    19861 tccttctatt tttgccgtat ccatcgattc ccgcagttcg ttttttttat caattagctt
    19921 ttgatacacg ttcttcagat atgcttcttc taactgtttt tgtgtgttga ccatacacat
    19981 tctcctcttt ttttaaagtg gtggaaccga ttagtttacc tcttttaaga gtcgaatgca
    20041 agctttttaa cgagtatcat ttgttaggat atatcagttc ttcaggtcgg acagtttgat
    20101 ataaagaaaa tgcaccatca aggtttttta cgtggtagcc agactgcttc aagattcttt
    20161 ccgctagata gctacgtaat ccgctatgac agctgacgat atattcttgt tggctgtcta
    20221 attcatttaa tcggtcccga agttcattca aagggatatg tttggcttcc ttgaatttgc
    20281 ccttttccaa ttcttctgct gttcgcacat ctaataaaat ttttcctttt gctagttctg
    20341 tcggcaattc atgccattgt acggtttcac taagcccttc tgcaatgttc attgctgcat
    20401 atcctagcat gtttactgga tctttggctg agccaaatgg cggtgcatac gtcaattcta
    20461 attccggtaa atcgaagatc gtcaaatgcc ctttgattgc tgttgctaaa atatcgatcc
    20521 gtttatccac accttttgcc ccaacacctt gtgcaccata aatctcgcca gtctctggat
    20581 ggaagatcaa cttcagtaaa atatctgttg cttctggata atagcttgca tgatcttttc
    20641 ctgatacatg aatgacttca aaagacagtt cgttttcttt ggctgttctt tcacttaaac
    20701 cggtggatgc ggcagtcatt ccaaacgttc gtataattgc tgttccaata ccgccttgat
    20761 ttcttcgaga aattccggaa atcgtgtccg caacttgtct accttgacga ttggctggtg
    20821 aagcaagaga aataagtgca tcttttccag tgatttgctg ttttacaacg atagcatccc
    20881 ccaccgcata aatatcagga atattcgttt gataacgttc gtctactagg atacccccgc
    20941 gtatgcctaa ttcgattcca gcggtcactg ctagctggtt atcaggacga acaccaatgg
    21001 ataaaataac taaatcagca gggatggtac gcccatcatc cagtcgcaat cgtttcccgt
    21061 ggtcttcaaa tccagcgaca gcatgagaag taatcacttc tactccttga tgagacaatt
    21121 ctttttctat aaaagctgcc atttcttcat ccagtgttgg aagaatatgt ggtgcttgtt
    21181 cgatcaccat gacttctaaa cctcttcttt ttaggttttc tgccatttcc aatccgatga
    21241 atcctgcacc aacgatcacg gcacgctttg gctgtttttc taatgcatgc atcactttat
    21301 cgatatctgg tacatttcta atagaaaaaa cattgtcggc ttctgttatc cctggaatcg
    21361 atggaacaac tggttttgca ccaggagata aaaccaatgc atcgtactgt tcaatgtgtt
    21421 tttgaccctc atgtacgact tctaccgttt tgttttcggg aaagatggct gtcacttcat
    21481 gatttggacg cacatctaaa caaaaacgag cggataatga ttctggcgtt tggacaagaa
    21541 gattttcccg ttcactgatt tctcccgaaa gataataagg caagccgcaa tttgcaaaag
    21601 aaacatacgg tcctttttca aaaacaacga tttctgcatc ttccattaat cggcgaagcc
    21661 gtgtagcagc agacattcca cctgctacac ctccgacaat aacgattttc atcttatttc
    21721 cctcctactg ttcgatcaaa ccattgattc atgccaccac gtacattcac tacatcataa
    21781 ccagatttct ttaattcttt agctgcttgt ttactcctca tccctgattg acaaatcaca
    21841 tagacggtct tttctttgtc tccatcatat ctgtttatac tttgtaatgg aacattttta
    21901 gctcctttta tatgcccgcc ccggtattct gcaggtgttc taacatcaag taacgctgga
    21961 ttttccaaaa gcttttcctt taattctggg actgttatcg attttattga ttgaaatagc
    22021 aaattcattt tctgcacctc atttacattt ttataaatac ctcatggggt atattaaaca
    22081 ggagctttat taatatgtca accagaatga ctcttcattt ttttcactac tttttatatt
    22141 tgcataaaat accgataagg ggtattatct aattataaaa atagaggaga atgtgttatg
    22201 gagattgata ataaaaatat cctgaaccgt ttgaaacgta cagagggaca aattcgtggt
    22261 atccaaaaaa tgatcgaaga cgaaaaagaa tgtatggatg tcatcactca attaagcgct
    22321 gttcgttcta gtattgatcg cgtaatgggc atgatcgttg cagataatct gaaaaattgc
    22381 tttgagaaac ctgatagtaa tccagaagaa caagcggcta aactagaaca agcgatcaag
    22441 atgattatta aaaagtaaag gaatgatttc aatgaaagtc gttttccata ttgatgaatt
    22501 agaaaaatgg tcagaaacag ggaaaaacgt aaaaaacctg ataaaagctt ctccagaaac
    22561 gacgattgtc gtatctgtaa atggcatcgc gattaccggt tatctagact ctgccaatgc
    22621 agaattctta gatttgcaag gagtcgtttt tcacgcttgc gccaatgcta tgcgtgctaa
    22681 tcatatttca gaaagttctt tacctgaaca agtaatcgtt gtaccagcag gtgtccttga
    22741 tttagttgaa ctgcaatccc aaggttatgc ttatatcaag ccttagtcag tagaggttgc
    22801 gacagaagtg atcagcttca agaaatttcg gcttattttt cgaagaagct acttctggaa
    22861 aaccgtgaat caaaggttgt gaaaacgctg tcctgcatca agtaataaga acagccaaac
    22921 aaaaatagct tctcatattt ttcgtttggt tgggcttatt accgcagatg caagcttttg
    22981 aacaccgttt aaggaagagg ttgtgaaatc agcggtttga cctaagtatt agagaaaaaa
    23041 acgggaaaat agctcctcat attttgccgt tttttgagct aataccgaag gtcagctgat
    23101 tgaacaccgt ttaaggaaga gattgtgaaa aagtcgctta gtttcgagta ttaagaaaaa
    23161 ttttgtgaaa atggatttct acatttttgc ataaatttgg cttaataccg agaaactggc
    23221 ttttgaatac cgtttaagga agaggttgta aaatcagcgg tttgacctga gtattagaga
    23281 aacaaacgga aaaatagctg ctcatatttt gccgtttttt gagctaatac cgaaggtcag
    23341 ctgattgaac accgtttacc aagaggttgt gagcctacca tttaactccg aatcacaaga
    23401 aataatttca aaaacaactt ctcctgtttt tggttcggtt ggcttattat cgagaagtag
    23461 ctactgggag tctatttatc aaaaaaagga atgcgacata ggtcacaccc cttttttatt
    23521 ttctttgaaa catctttcgg tactcgacag catacaagac aaaagattgt aaaagaccgt
    23581 aagtgatgac ggcaaaaatg actctcaccc acagcgttgg taattctggg aaaagcagca
    23641 aaaggatcat gccaacatag atgacagcag tcgctacttt gccataccac ttcgctccac
    23701 ttaatttgat atttttagat agcccgatta atccagctac aaacataaag ccttctttta
    23761 tcaagaatag accaaacaac agccaaagcc acggtcgata ccatgccata gacaaaatca
    23821 gaaaaagttg tgtcaattta tctgcaaacg gatcaagcac cttccctaag tctgttacct
    23881 gattatatct ccgagcaatg accccgtcta gataatcaga caaacctgag acaacaatga
    23941 ccgctcctgc tatataaaat gactgtctca gcacaaaata aagataaatc ggcagcaaaa
    24001 aaatacggaa tatcgataaa agattcggaa tcgtttgtat ttctttacgc cagtctgtgc
    24061 ttaatttcat tttatcgccc tacctcctca gcactctttt ctttttattt tagcttacac
    24121 ggggaataaa accaatgatt tcactgtttt tatttttctt tacagacact gatattatga
    24181 gctaatttga gataatcact tgctgttttc atcgtttact cttctttctt cctgtcgttt
    24241 gcgcatttct tttactagta ctttatgagc tttttttgat cctcgctcta ggtcacgctg
    24301 ccgtttacgt gttttataat cgataaacag actgtctaaa tcgtaacctg tcgggtacag
    24361 atcttctgct gaacgcacca gacgaacacg ctgacgaggc acgtggatta tttttttgtc
    24421 taaatataca tcaatcgtat cttcacctat atcttcataa actaacgctt ctttttggta
    24481 ttcattgaca aatatccgat caccttttgc aaagagctga cgttcttttt tattctcctt
    24541 cctatttgta actgctgtct taggaagaaa ttcttttttc tgtgtccgat aggctttttc
    24601 cgccaagtaa cgctctgctt gatggatcaa tttcatcgac atatccattt tatgagcaat
    24661 ccacaaagct tggctttctc ctgtttcttc caacccgcaa ctgatattta ggacgaagtg
    24721 cttcccgatc gaaagccata gcagccggca caaaatcttc atgatctccg gcgaatttct
    24781 tgatttctcc ataatgggtc gtggcaatga tcaatgcccc ttgctcatac atagattcca
    24841 tgattgcgat cgctagtgca gccccttcat ttggctctgt tccactgcca atctcatcta
    24901 aaagtaccaa cgtattcctt tttatctttt tcaaaatagc agcgatgttt tgcatatgac
    24961 cagaaaatgt actcaacgca ttttctaaat tttggtggtc accgacatcg acgaaaatct
    25021 catcaaagac agcaagctct gtcccttctt ttgccggaac ttgcataccg aacatcgcca
    25081 tcaaagtcaa taaaccgact gtcttcaaca cgactgtttt gcctccggca tttgctccgg
    25141 tgataatcaa gcctcgatag tctttaccga tttcaacatc caatggtacc gcatgctcag
    25201 gtaaaaatgg atgtctgcct tgcttgataa tgatatgttc cgatttattg attctaggtg
    25261 tgcttccatt gatttctcgg ctaaattttg cccgagcaaa gatgatatct aacaccgtga
    25321 tcgtttcgat caataaatcg atcacttctt cgttttctgc gatagcacca gtcaatgccg
    25381 ccaggacttg atattcttca ctgatttctt cagcttttaa caactgatag tgttcattca
    25441 atttagaaat cacagttggt tcaataaaaa ccgtcgttct tttatttgat tcatcgataa
    25501 tcgttccatc tattttattt ttatagctgg ctttgatagg aatcgtatag tattcgcctt
    25561 tttgaacaat cattgcttct tggatcattt ctttgttttt cggatgacgc aagaatttca
    25621 gtaattttga ctggatttct ttttcgatta gttgtaattg tttgcgtact ttacgcaaat
    25681 tacgtgacgc gtcgtcactg actttattat tttttatttt ctggtcaatc aactcttcta
    25741 catttatcaa atcaggaaga tgtttgctat aagcaaacaa caagggtgtc tggtattgat
    25801 tcttatcaaa aaactttgtg atcatccgac tgcttctaag aaaatccgca tattcgatca
    25861 aatcggttgg ctgcagaatc aacccttttt tgacttgttc tgtcagtgca tcgatcctcg
    25921 gcaaccccat aaatggaaca tgctgactgc tttctaagat caagcgtgct tctcttgttt
    25981 cttcttgacg atccaagaca gtttgtaggt ttgtcgagac cgtcatatcg ctgattcgtt
    26041 ttttgctata gtttccaatt gctcttgctt ggatttcctt tttgatccga tcaaattgta
    26101 attgactaat catttcgttg tccatattct ctccttttct tgaagagata cctgtcccaa
    26161 aataaataag ggcctagaga taaataaaag gatagaacac agcttaaaaa agtcatgtcc
    26221 tatccttatt agaatacaaa gatattgttt tcctgacagg taccgtttca taagcacacc
    26281 aaataaactt tgtttattgg ctattcgact tactgattag ataccagcta cactcacaaa
    26341 acatacccca ttcttctagg tcttatttat tttccactta actatagcaa gacacatttt
    26401 ggttgtcaaa ctttagtatg ttttatagat ttacaccatt aatgaataga cacctaccgc
    26461 gataattgct ccgatcattg gacctgcgat tggtacccat gaatatgccc aatctgaagt
    26521 tcctttatta gctattggca ataccgcatg tgctaatcga ggaccaaagt cccgagcagg
    26581 gttgattgca tatcctgttg gccctcctaa tgaaagaccg atggctaaga tcaatccacc
    26641 tacagcgaat acgttcgttc caggtgcaaa ttcgttttgt ccaaaagcta gcaacccaag
    26701 aactaataca aatgtaccaa ttaattctgt gatcacattt gctggataat tccgtatagc
    26761 aggacctgtt gcaaacgttc ctaaaatcgc gctttcatct ttcgttgcat tccaatgtgg
    26821 caaataagaa agccaaacaa gaatggcccc tgcaaaagct cctaaaactt gcgcaatgat
    26881 gaaaggaacg acaagattcc aactaattgc ccctgtcatc gccatagcta gagagactgc
    26941 aggattcaaa tgagctgggc ccatgaatcc agaaatatag acagccattg ttacagcgag
    27001 tccccaacca aatgcgatga caatccagcc agaagcctgt gctttacttt tgtttaaatt
    27061 cacagccgca cacacaccat ctccaagcaa aactaggatc agtgtcccaa taaactcccc
    27121 catgatttga gtcatatcac tgttcattta tttctccccc tttagttccc gcagatctga
    27181 ttctgcaatc aatgcttcta aacgtttagt ctgttgcgcc ttctcctctt ctgtccattc
    27241 aaaatatcca gcaattgcat cgatcacagg ttgcttgatc tcatcaagct gatctcgttc
    27301 aaacaacaga tgatttgtac gacgaatgag ataatcgcct ggggccaaaa ccatttcttc
    27361 ttctaaacca taacgtaacc gagctgactc agcgagactc aaaccaggat aaggtgccat
    27421 ttcttttgct aattcaaaga tacgtcgggc attagtcccg taaaaatcag cgatataagt
    27481 agcatcttct tcctctaaac cggctgctac tccttctttt gctaattctg tcactgtttc
    27541 ttctaattta gttggatcga agtttccacc tgaaatctga tattttttag agtcgatttc
    27601 tttcgtctct attccgtatt cttcttttaa taattggcgt atcaatcgca aagctccttc
    27661 tgccatctta cggtaatcgg tgattttccc accagataaa gtcagcaaac catctggttc
    27721 tctttctaaa gaactacctc tggaaatcgt agaaggtgct ttttcatcac ggctgttttc
    27781 caaatggttc aacacgtctt ctacttcagc acgagaaact ttgttttcct tatattcact
    27841 tactgtatcg acaactttat tgaagctctt gtctgaaatc gatccattat ctccaccatt
    27901 gtaatcagaa ccagaattac caatcaacag tggacgaagt cctgcccagc ttgcttcgat
    27961 atcattcaat gtgatatttg cttctggata gcgatgattg atcacatcca atagataatc
    28021 tacatcttct tgtgtgactt tcggatccgt aaaatctcct tggtaatccg tatctgtcgt
    28081 accaaagtaa gtcttgtttt ctcttggaat agcaaaaacc atccgcccat cttgctttcc
    28141 tgtatcgaag tatgtgggtt gcggtacagg cagttttttc gcatctacaa ctaaatggat
    28201 ccctttagtt ggacgcattt taggagagac tggacgcgta aaattcaagt ttcgtacttt
    28261 atctacccaa ggaccactcg tattgatcac taattttgct ttgatttcga tcacttcatc
    28321 tgtcagcagg tcacgagctt tgacgccaac gatttgatcg ccatcatata aaaagccaac
    28381 cgctttcatt ttacttacta gataagcccc atcttcggca gcctttttga tattatcaat
    28441 cactaaacgg gcatcattgt tgcggaaatc tagatagaca cccgcgcctt ttagcccttc
    28501 ttttttcaaa aacggttctc tttccaatac ttcttctggt gtcagcgtat aattctcata
    28561 tttggttcct gtcacatttg ccagtttgtc ataaaggtcc attgctactt tgaccgagaa
    28621 catattgaag gttgttgctc cttcgccctc atagattggc aaaagcattg gatctggttt
    28681 tgggatgtgt ggggcaatac tttgtacgac tgcacgttca ccaactgtgt cagctactac
    28741 ttccacatca aatgtcttca gataacgaat accgccatga acaagtttgg tcgagcgaga
    28801 ggaagtccct tctgcaaaat cctgcatttc gatcaatcct gttttgattc ctgatgctgc
    28861 tgactggact gccacaccgg caccagtgat tccgccaccg atgatcaaca gatccaattc
    28921 ttcttgctgc attttttgaa tgctatcttg tcttgtcttg tttgaaaaca tatggatttc
    28981 ctccttattc aaatgcttgg gtagctttta ctgctttttt ccaaccgttg taaagttttt
    29041 ctcggcgctc ttcctccatt tgaacttcaa atagcttgcc agcttcataa aattcgcgga
    29101 tctcgtctgt atctttccaa taaccgacag ctaatcctgc taaaaatgct gcccctagcg
    29161 ccgttgtttc caagttttct gctcgttgga tcggtacatt caagatatct gtttggaatt
    29221 gcatcagata ttcattgttt gctgcaccgc catctacttt caatacagga atcttgattc
    29281 cagtgtcatc ttgcatcgta tcgatgatat ctctcacttg ataagcaatc gactgtaaag
    29341 tagctttaat gatatcttct tttgtcgtac cacgtgtcaa gccaaacata gcccctcgtg
    29401 ctgcctgatc ccaataagga gcacctagcc caacgaatgc aggaacaaca taaacctcat
    29461 cttcgcttgt agagcgtttc gctgcgtctt ctgaatcgct agctttttgc aacatttgaa
    29521 gtccatctct cagccattga atcgaagaac cagccacaaa aatacttcct tctaaagcat
    29581 agtaaacctt tccatttatg ccgtaaccaa ttgtcgtcaa taaattattt ttggataatt
    29641 gcggtttttc accggtattc atgacaataa atgaacctgt accataagta ttcttgacca
    29701 tgcctggttc gaatgccatt tgtccgaata atgcggcttg ctggtctcct gccatccctg
    29761 aaattggtgc ttcgcttcca taaaaatgat aaccttgcgt ataaccataa acttctgagt
    29821 tagaagtgac ttttggtaac atcactcgag gaatatttag taaatctaaa atctcctgat
    29881 cccaatctag ctgatggata ttgaacaaca tcgtccgact ggcattcgag taatcagtaa
    29941 catgtgcttg tccatcggtc agtttccata ctaaccaaga atcgatcgtt ccaaacatca
    30001 attcgccttt ttcagctcgt tcttgcgcgc cttctacatg atcaagaatc cagcgtatct
    30061 tcgttgctga gaaataggca tcgatcacta accctgtttt ttcgtggaaa aattcttgat
    30121 agccttcatt ttttaagtta tctgcaattc cagctgactg tctggattgc caaacaactg
    30181 catgatagat tggacgtcct gtatcttttt cccatattac tgttgtttca cgctggttcg
    30241 ttatgccaat cccagcaatc tgatttggtt tgatccctga ttcgatgaac gctccggcaa
    30301 taactgactg tacagaattc cagatttcat ttgcatcatg ttccacccaa ctttcttgcg
    30361 ggaaatattg cgtgaactct ttttgagaac tgccgatgtg tcttcctttc ttgtcaaaga
    30421 taattgctcg tgagctagtt gtaccttggt caatcgccat gatatacgtt gattctgtca
    30481 ttgtgattcc ctccattata tgcaaacgct ttctttaact actcttatca tactactgtt
    30541 ttaaaaaaag aaactgtcaa aattttattc tttttttctt tttttgacag ttttttatta
    30601 tgaagctatt ttttaatcaa ttcttttctt ttttcagcgt ctctattctt cttttcaatc
    30661 gaataatgtc gtaaggtgac gcaaattctg acagataata ttcacactgt tttttgtttc
    30721 tctggcaaaa tgtgatcacc aaatcatatt ctttaccttc ttcataactt ccaatctcaa
    30781 taccgccgat tcccctcagt tctctgatca gatattgttg aaaagcaata cgataaatcg
    30841 gcagactttc taaatcgatt ccaatcacta ctggttttgc aatataaaaa tcgatcatca
    30901 aaagaacatt ggcatactgg atcatcaggt aactaagctc actatcttca gctcttttcc
    30961 tcggcaattg ctgcaccgct gtttcctgta atttcgccag taactgtgtt aaggaatgcc
    31021 cgagcatttt ctgctgctgt tccaaaagcc gatcacgctc atagacttcg atctttccaa
    31081 caaagaaaaa ccattcattg ttgatctggg aaatttggta gcctactgcc ttttcttctt
    31141 tgattttcaa acgacgagga cgataatgcc ataacatcgt ttcccgaatg taagtatcta
    31201 aaacagcggt tggtaacttt ttgctccgtg tcaaatcata ctgataaaat atttcttcgt
    31261 ctactatcga aaaagaaaca aaaaagctgt aaaacatcat tgtttcgtat acattcagtt
    31321 ctgctgctgt tcgactaaga tgcatcacga tgattggatc gattgcttga taaagccggt
    31381 ccgactgata gagtaatttc ttttctttca aagttgcgta cgtacttttt tcattcaata
    31441 gtcttttttt cgtaatcccg agccagcaag caatctgtgc ttctgctgat gccgtaaacg
    31501 ttgtttctaa tacacggtcc aatcctagaa tgaacggtct tttttctggt gtattttgca
    31561 aaaaaagcgg tcgctgatct tccgggatat attggaatag ttcataataa aaatatcgta
    31621 tctgtagctc ttctccgtat aattgaccgt ttttgatttg taatccaaat tcctctaaga
    31681 gctggttcaa ttctttgatc tttcgaaaaa cagaagactc actgatatta aacgctgtcg
    31741 ctaatcgaac gatggatact tgctgatgtt ctaataaata gacgagcatc ttaaacttca
    31801 agctttcctg caataaaaac aatagaattt tttccaaact tacatcttcg tccaacacaa
    31861 gcagcgcctg atactcattt cgctgtactt ctactttttt ttccatcatt cggccaatca
    31921 attcaatatc ttccaaatat tgatcaaacg aggcttttga cagttggaca tgctctctca
    31981 aaccattgat agaggctgtt cccccttgca gaacaaggtt tcgcaaaatc aggatctgta
    32041 actgctcttt tctttctaat aatgcttcaa tcttcatagg cagtattcgc cacctttgac
    32101 cacaccatat ctggcacacg gtattctggc tggaaaaata gctcatgttc ttctaactgt
    32161 tcaaacgtcc atccttcttc tactgcaatt gtcagttggt caagaaggtg gaacatctct
    32221 tttttgcttt ggagctgtgc tccaagaatc tttttttcag aatcaaatag aaatttgagt
    32281 ttaactttgc tttgatttat tgctgtaagc ttgtagtcta cgtatcctgt ttcaattttt
    32341 tggggataaa aaatgctctc ttcttctgtc aaacctacgc ttcctaagaa atagccaaac
    32401 cactgattgc cgactggacg ataggttccc tgatcctttg tctgtgagcc actaattgtc
    32461 ttgctgacat ttcgtgctgt acggacagcg ttatttacta gagaaacata cattttttca
    32521 tttgttggac gaaaagttac ttggatcgca tcgccaatcg cataaacgtc tttttgagac
    32581 gtttgcaagt agtcatctac ccagatcgtt ccatcatcat tcaatgttaa ttgttcttcc
    32641 cacatctgat tgtcgggacg agaatgatta gccagcaaaa caagatcata gttctccttt
    32701 cttttttccg tctctacaat agcggtttca ttttcggtca aagacacaac ttgttcttct
    32761 aaaaaaagtg aaagcccttg atttttcatt tcctttacta acggttctgt catttcagga
    32821 tctagataac gaaaaagaat tgactttcgg ctttcgtaaa gatggatttg tttttttctt
    32881 gatgccaacc cttcagctat ttcgattcct gcttgtcctg caccaataat tgcaattttc
    32941 tttgcattca tgatcttttg ctgaagagcc gttacgtttt gtatcttttt aactgggtga
    33001 ataagcgttg attctgcaga aatatttcga aacttttgat ttgaaccagt cgctagaatc
    33061 aaacgatcaa aatccaattt ttttcctcct gctaaaacga cttttttttc tttcaatcct
    33121 attactgtct tttctgtgta aacatggatt cgatagcggt cagtcagttc ttctttcgtg
    33181 atccaagaaa gttgtttttc actggtaacc tttcctttta atatcaaatt gaacccgctg
    33241 ggaatccatc ctaacttcga ttgcttttca atcaaatata tttcacttgt tggcatcaat
    33301 tggcgaagat aaatagccgc atgaatccct gcaaacgacc cgccgacaat tacaatgttc
    33361 atctgcattc ctctttctta taaggtgttc tactgctaac ttctcaatca gaaaacacag
    33421 tattcataac tcgctttcaa ccttatgata catagcgatg cagcagaatc aaccctctcc
    33481 atcataccgt gttctaggtc tgcttctcaa taatgtacta gtggacctaa ttgaagagta
    33541 tcatttctga agagatgttt caaaaaatgt actcttataa aagaaaaaaa ctcgcctttt
    33601 acgtacctct gtccaaatag gaaacagaaa agaacgaaaa gacgagtttt agcgtgtgta
    33661 atgtaatagt tagaatagac acatcattta tttttaattc tttaatgctt caacaactgc
    33721 ttcgcctaat tgatgagcag attgaggatt ttgccctgta agaagccgcc catcaatttg
    33781 aaccacttct gaaaaagctg ctccagactg atagtttgct cctttttctt tcaaagcatc
    33841 ttctgctaag aatggtactt cattcgttgt accatttgct tcctcttctt cattactgaa
    33901 cccagtcact gtacgtccag ctaaaataga ttttccagac tcatctgtaa ctggcaacaa
    33961 tcctacaaca ccgtgacaaa cagctgagac cagcccttca tttcgataga tttgtgaagc
    34021 gactttccca agatctattg cttctggaaa atcccacatt gttccgtggc caccagcata
    34081 ataaaccgct gcataatcat ttgcatccac atcatcagga cgtaaggtat ttcccaaggc
    34141 ccgatttctg aaatcttcat cttcataata ggcccaatcg atttcatcca tattcaaaac
    34201 actttgcggt tctaaaggta catatccgcc tttaggactg acaaaatctg catcgatccc
    34261 attttttact aatacatcat aaaaatgagt cagttcactt aaccacaaac ctgtaggacg
    34321 ctcgatcttt tcgtactttt ctacatttgt taatacgatc aatactttca ttttcccatc
    34381 ctctttctat aaaaattgcg ttattgataa cgtgctttca agaaattata taatgggctt
    34441 ggcaaataaa gctctttata tgctttttca aaaggtttcg ttacaaattc atcctcacgg
    34501 ttttccaata atttctctgc ccagtcagga tcgacgatca tttgctgtcc aattgctgca
    34561 agttctgcat atttcaatac ctgctctaca tcttcgcgat tgcggatccc accgacacca
    34621 actaaaggga tctttccttg aatcgtgtta tggaccactt caagaatcga tttatcgttg
    34681 tatttatcag aacgagctat tcgatcatac atatttaatg aaacatgcag ataatctagt
    34741 tttgactcac gtaatcgttc aagaagccag atcgtgtctt caaaacggat acctggtgtt
    34801 tcatattctt ctggtgagaa acgataccct acgatgaatg gttttttagc atattgttca
    34861 accgctgaga aaaccgttgt taataattct tcaataaaac gataacgatt ttccaagcta
    34921 ccgccccatt gatcctctcg tctattcgaa tgcggagaga aaaattgttg gatcaaatac
    34981 gtatttgctc catgcaactc gattccatca aatcctgatt caatcgctct acgtgtggct
    35041 ttgccaaatg cttggattgt ttcaacgatt tcttcttcac tcattgctcg tggtgtttcc
    35101 gcatcaggac gttttgctgc aactgcactt gcagatacag gctgttctcc agataaagtt
    35161 gctcgacttg tcattcgtcc accgtggaaa atctgaataa tcgcttttgc gccttctcct
    35221 tggattgctt tcgctagctc acttaatcga ggaatcattt catcatgagc gatgctgagt
    35281 tcacctggcc agccttttcc gatatcttgg acatttgcag caccagtaat aacagcacca
    35341 agacctttag aacgttgttt ataataagtg atctcatctt cggtgatcac tccattgaaa
    35401 aagctgagtt gtgtcgtcat aggcgacagc atcaatcggt tcttcaattg aactcctgaa
    35461 ggtaaagtaa ttgattgatc aaattgtgac attgtcattc ctcccataat tcgctctgat
    35521 taacctatcg agaatcatct atcattaaac cactcgatta gttgtacatg caactaattt
    35581 gcttaaaaaa ttttattttt tttgtaactt atctgttgca tcattcattg tctgggctaa
    35641 ttctttactt gcttcatttc ccaaaactgc tttgtatgac tgatgaagtt cttcccagct
    35701 accatcgact tccttagcaa attggcgtcc ttgttctgta agataaacta atgacaagcg
    35761 accttcgcta actgttttga cgtatccttt atattctaat ttttcaacaa aacgagcaat
    35821 cgttgatggg gcggaataga gcatttgtgc aatatctttt tgtggtattc catctttttc
    35881 ttttaatatc aataaaataa aaccataagt tggtgccaga cctgtccttc taaacgcttc
    35941 atcagctaat ttattcaaca tgcgatctag ctttttcacg ctaaagaaaa gacattcatc
    36001 taacgctttt tcaattggct tttccatttc atcccctcca ttggcgtaca tatcatagta
    36061 tgatttttat tttttgtcaa aaaacacgga ataatgtccg cctcctctgt ctagatttga
    36121 aaaaaagaag tagccatctt caaagaattt cggcttgttt tcgacaaaac tccttctgga
    36181 acaccgtgaa tcagaggttg tgaaaaagtc gtttagtttt gagtatgaag aaaaattttg
    36241 tgaaaatggc tttccacatt tttgcataaa tttggcttaa taccgaaaaa ctggcttttg
    36301 aacaccgttt atatcagagg ttgtgaaaaa gccgtcctgc atcaagtaat aagaacagcc
    36361 aaacaaaaat agttcctcat attttgtcgt tttttgagct aatgccgatg gtcagctgat
    36421 tgtacaccgt ttattgagag gtcgtgagcc tgccgttgaa ctccgagtca caaggagcaa
    36481 tttcaaaaaa cagcttctca tgttttatga ctatggtgac ttgtgatcga ggagttggca
    36541 ggagaatact gtttattcgt aaagaagggg ctgtgacaag acttttgtca cagtccctta
    36601 tttcctttta ttataggatt tcgccatttg attggatgac ttgtctgtac caatcaaatg
    36661 attttttctt taaccgtttc tttgtgccat tcccttcgtc atcttgatca acatagatat
    36721 atccataacg ttttgacatt tgtgaagtag aagcgctgac gatatcaatg cagccccacg
    36781 acgtataacc aaataaatct actccatctt tgatagcttc cttcatctgc tcaatatgct
    36841 gcttcaaata gtcaatgcgg taatcgtctt gaacggttcc atcttcttct actttgtcta
    36901 tagctccgag tccgttttca gctatgaaca gtggtttttg atacctatca tataattgat
    36961 tcaaagcaat tctcaaaccc ttaggatcaa tctgccagcc ccattcactt gatggaagat
    37021 acggattttt aattcctcca gttattaagt ttccttggac cccttcccaa ttttctggat
    37081 gagcactgac tgcactagac atgtagtagc taaaagaaac aaaatcaaca gggtaggctg
    37141 ctaagatttc ttcatcacct acttctattt ttaagttgac acctttttct tcaaacattc
    37201 gttgcgtata cgctggataa tatcctcttg cttgaacatc actaaagaac aaagaagttc
    37261 tttgctgctc aattgttttt tgaatatcat ccggatcaca agaatacgga acaagaagct
    37321 gatagctgat catacaaccg acttgtgaac ctttgataat ttcatgacaa gcttttgtag
    37381 ctaaagcact tgctataaac tgatggtgtg caccttggta tttcgcttgt tccaaatggg
    37441 gatggttttc ttcaattact cctacgctaa caaaagggtg atgttttaca cagttgatct
    37501 cattgaaagt catccaatat tttactttat ttttatagcg tttgaatact gtttcagcga
    37561 aacgaacgta aaactgaata agctttcgat taggccatcc accatattct gtaaccaaat
    37621 ataacggcat ttcataatgg gaaagagaaa cgactggctc aatcccatat tttagacatt
    37681 cgtcaaacac ttgatcataa aaaaataatc ccgcttcatt gggtgtttct tcatcaccat
    37741 gaggaaaaat tcttgtccat gcgatagaca tccgatagca tttaaaaccc atttcagcaa
    37801 ataaacggat gtcttcttta aagtgatgat agaaatcatt tccgtgtctt ttaggataat
    37861 aatacttgct gttgggatcc tgcgccgctt ttacttgctg atgcgtcatc atatgccatt
    37921 gatctgtcca tttttcttta ggtaaatcgc tgtcgaatgt atacacatca gacacagata
    37981 atcctttttc atctacatcc catgcacctt cacattgatt ggccgctgtc gctccgcccc
    38041 ataaaaatcc ttctggaaat tttttcatat cgatccccct aaacttgcta gttttcttgt
    38101 ttgattattt ttcttatgac tagtaatgat atttttgaat ctactactat ttgtaacaat
    38161 aaccattgtg gtcggatcat atccctcttt gattaattct tgcaaatcta cttccatcaa
    38221 taaatcgcct ttacgtactt tttttccatc agatactgca ctttgaaagt atttgccatt
    38281 taaattcact gtatcaatac cgatatggat cagtatctct gctccttctt cactgactac
    38341 cccaattgca tgtttcgttg gaaaaactgt tgaaacttcc ccgtttacag aactgtagat
    38401 ttttccgtcc gttggaatga tcgcaaaccc ttctcctaaa gatccactag caaatgttgg
    38461 atcgtttact tcagataaat caattatttc acctgctgca ggagtactta acactatatc
    38521 ctttgaggat tcttcttcga tttcatcctt gtagccgaaa agaaaagtta gcatacagga
    38581 actgatcatc gctaagaaat aactagcaac tagccaaaca aatccttcac caatataaat
    38641 cgggaaagac aaaatacttc ttgtagcaac tgccaaagca ccggctcctg cggcaccagc
    38701 tactccacca aatatagctc cacatataca agcaatgtaa aatggtcgtt tatatttaag
    38761 agtcacacca taaacagcag gttcagtgat tccaaataat gctgtgataa atgcagataa
    38821 agataaactt tttactttct tatttttcgt tttcaaaaat accccaagta ctgctcctgc
    38881 ttgcgcagct acggcagtca tacatgctgg acctagcgta tcacgaccgt agaaagaaag
    38941 attgttggtc attactggta caagtcccca atgtaaccca aaaatcacta acacttgcca
    39001 aaatccgccg ataacagcac cagataaaac agggctaaag ttataaacag ctaaatatcc
    39061 agctgcaatc agctgacttg cataatctgc aattggacct acaactaata aaataattgg
    39121 gaccatcacg atgatacaaa tgaatggtgt caataaattt cgaatacttt cgtgcaagct
    39181 tttgcgaatc ttaggctcaa tataagaaag aacccataca gctaaaattg ctggaataac
    39241 cgtacttgta taccttgcta gaatcacggg catccctaga aatcgcaagg ttatgctatc
    39301 actatatgca ctgacaatcg taggataaac gagagctgct gcaataacca tagcgatgaa
    39361 acgatctgta ttgaactttt ttgcagcagt atatgccaaa aatataggca agaaatagaa
    39421 aaatgcatca gctgctgcat tcaaaatgat ataagttcct gattcagtag ttaataaatt
    39481 caaactcgta cataaggcga gtactccttt gatcaaacca cttcctgcca agacgcctaa
    39541 agtcggggca aaaacagcgg cgatcatgtc tataaaagag tttaaaatgc cttttttctc
    39601 agttcctctc tttccactag atgcatcatc ttctagtttc atttgtttgg ataatacgtc
    39661 atacacttca tttactgcat ttcctactac gacttgaaac attcctccag cttcgactac
    39721 agtgatcaca ccttctagtt gctctacctt ctccttatct gccttcttat tatcttttag
    39781 ggtaaagcgt aaccttgttg cacaatggta aacattgctg acattttctt cgcctccgac
    39841 aaatcggaca atatctttcg ctaattgtga atagtccatt tttacttccc ccttgttaat
    39901 taatgccgta gcaatccttc ttacaagata agtatagttc ttagaaaacg gtttctccat
    39961 tcaattagta ccccttctaa tagcgaacga aactgtacaa tagtgtgtat ggtttactta
    40021 gccgagcaaa tcactcactg cttgaaagaa aacaagtata tcgtttctct tatagtcaaa
    40081 ggagacaaaa aaaacacgct tgatcttcct ttgctgatgt ataagtggta tctcaagctg
    40141 atactctgtg atttttgttt ctacttggct tttgataaga cagcacaaca aagtctcggc
    40201 atttaacgga agcataacta ggtcagaact aggagagatt agttgctgaa tggaatctat
    40261 ctttttatgg atttttattt gattttcttc tttgtagtaa tgatcaagca gttttgtttt
    40321 ctttttttct tcaactatgg tcagcttttc acgcaaaatc tgataaatct cccaagattc
    40381 aaactcatct agaacactag gtagataaat caaatcatcc cactcaaaaa taagctcttg
    40441 ctcagtagtc aaaattgcat catattccgt tattttgttt gattgatttt tgaaaagata
    40501 cactggttct atccggcatt ctttgatcca catgttcata ctttgttgaa tctgtttttt
    40561 tagtgtattc aaaatactaa ttggctggtt actaacaatc agtatctccc cttgttttcg
    40621 aaaaggattc aacgcttcgg caagatacaa aacaaaataa gcgctttcag ctaaattggg
    40681 acgtaattga aaatgtattg ggaagaaacg ccgaattaaa taaatttcta aaggataacg
    40741 ggagatgatc ttttgtacaa aatgattcat ggtattatgt ccggcatcca tcctcgtttt
    40801 catttgtttg atatgggtta gcaaaaattc tgtttcatgg aacaataacg aaacaggaag
    40861 atctaaaaaa cgaataatcg tttgctcaaa tgctcttaga ttcttctcta tttctttgtt
    40921 tttttcatca ttaatcatca aataatttaa ctctaatagt cgattttcaa ttgcttgttt
    40981 ttcttgattg gaaaaagaat agggtagttc tgatgataac ttttttgtga gggtctctac
    41041 catcggaata aataatgtat acctgtttgt tttttctaaa agttcttctc ttcgaagaat
    41101 ggtcaaaacg agataccgag aaaatcgtat gaagtcctct cctgaaacaa tataattata
    41161 tgatataaga acctctttta atgtcttttg gacagtcggc atgatattgg aaaaaattgt
    41221 actgatttgt tgaggaaacc ttgcgtgttg gatcaccgtt tctgttccaa caagagataa
    41281 gaaaattctt tttgaatttt cttcagcaat gatttttagt ccttttgtcg acgaaacttc
    41341 cagttctaat ttaggattgc gctcgatcca acgcaaaatc gtttttattt gtaatgatac
    41401 ggctgttttt gaaagaaaga aaatgtctgc tatcttttgc atactgacat accctttttg
    41461 aaacaataag tacgtcacaa tagttgaagc tcggaaatcc atgctggaat agattttatg
    41521 tttcgtcacc tcttgtatga tttgctgttt agtttcagat tcaattgatt ctaaaaaata
    41581 acctgaacgt ttatttgact ggataatgat tttcttctcg tagatagcaa gcatattttt
    41641 gatttcagtt tggatcgttt tcttgttggt acctaaagct tcagctaatt cttcgcttgt
    41701 tatccaatga ttcttatttc ttaatactac aagaatttgg agttgtcgtt tatttaagtc
    41761 catttgctta cacctcctct ttgttataaa catacaggaa aaacctctca aatgacaata
    41821 gtcacttgca gaggtttaaa aatcatttga agaaagatct atattcaagg tttttaccat
    41881 tagactggat aatttgttta taatattcaa aactatcttt tttcaatctc ctaaagcttc
    41941 cgctcccatc attttgtcta tccacataaa taaagccata tcgcttcctc atttcccctg
    42001 ttcctgccga tacgatatcg attggtcccc accataagta accaatgatt tggcaaccat
    42061 cttttattgc ctcagcaatt tcctgaagat gtatttttag atactcacaa cgttttggat
    42121 cgtggattcg attcaattca tctggtgctt catctagtcc aatgccattt tcaactatga
    42181 ataatggtaa ttcataacgg tctgtcaatt cattcatgac ataacgaaac cctagaggat
    42241 caattggcca actccaaggt tcgggagatt tttccttcaa aaagggatta tcgaaaccat
    42301 ttgctccgcc agtatctacg cgcatttctg cttctttttt atagacagcg ctacgataat
    42361 aactaaatgc aatataatct gccgtgttag cttgcaagca ctgttcgtct ccatctaaca
    42421 ttactggtgc acagtcttct tccttccatg tcctgtaaat ataagctgga taatgccctc
    42481 ggcacatgac atcggagaaa aaccatgaat tgcgtttaaa ttgcagtgaa ccaaatacat
    42541 tctctggatc acagtcatat gcataagtcg ctaatgcaga aaagctacac ataataccca
    42601 tcttagcatt tggatcgatt ttctttaata attgagtagc acgggcgttc gctagaaaca
    42661 tatgatgaca ggcttgataa atcacttttt ttgttagtgt agcaatgggt tcaagtttat
    42721 ctctagcagg gaatgtaacc aatccagcag ctgcataagg catacgaaaa gcattattga
    42781 tctcattaaa ggtcatccaa tatttcactt tcccttggta gcgttcaaag acggtctgcg
    42841 cataaaattc aaaaaagtcg attaattttc gattttgcca ccccccatac tctcctacca
    42901 atgctaaggg ggtttcataa tgactaagag taattactgg ctcgatatca tatcgattta
    42961 atgtattgat tagtctgtca taaaatacga gaccagcctc atttggcttc tgttcgtctc
    43021 ctcttggaaa tattcgtgcc catgagatgc ttgttcgaaa agcttttaaa cctaactcct
    43081 tcagtaaacg aatatcctct tcaaatcgat gataaaaatc aatcgcttca tgagaaagat
    43141 aatggagtga ttcgtctaaa gcaatctccc aaatcttttt ttcttcattc cactgaatac
    43201 taggatgctg gttcatgatc ccgataagcg tatctgtcac attaggtaat ttgccgtctt
    43261 ccaaccatgc accttcacat tgattagcag ctactgctcc gccccataaa aaattttctg
    43321 gaaatatttc ctgatccata actatctctc ctcgctatca acaatttctt acttgaagta
    43381 tagctcgatt catcaaaaca agatattcta actatttcgg cagaagagaa gaaaaaaatt
    43441 gaatgctact cttcattttt aatatttata tataacaaat acataagacg atccccgaaa
    43501 gaaaacactc gttaaccatc taagcaaacg atttatttta cttccaacac aaatgcttca
    43561 taaggtcgta aatcaacttt gccgtctggt aactgtttca gaggataatt tgacacaata
    43621 acccttaaag cttcacgtgg aatagtgaac gtctgctttt cactggacat attacaaata
    43681 acgagccatt gctggtcttc atatatgcga gaataggcaa agacatgctc aggcgtcttt
    43741 tccactaatt catagtctcc ccagacgatg atgtcatgtt ttctacgcaa atcgatcaat
    43801 ttcttgtaca tataaaaaac agaatcttga tctgctaacg cttcttctgc attgatttct
    43861 ttataatttg gattgactcg aagccatgga attccagtag taaacccagc atgttcacgg
    43921 gcgttccatt gcataggcgt cctagcattg tctcttcctt tcgccttgat tgattccaag
    43981 atttcctctt ttgtaaatcc agaagaaatc ctttcgttat acatattgat tgtctcaata
    44041 tcttttgctt ccgcgatatc atcgattggg caattcgtca tgcctaactc ttctccttga
    44101 tagatataag gggtgccttt catcatatgg agcaagatag caaacatctt ggcactttct
    44161 tttcgataca catcgtcatt tccccaacga gaaacaattc gcggaagatc gtgattattc
    44221 caaaataaac tattccatcc ttcatcacct aaagatgttt gccatttgga taatactttt
    44281 ttcagttcag agatactcaa gggtttcaaa tcccatttgt ctttgccttc ttgctgatct
    44341 aatcctatgt gttcgaattg gaagaccatg gataattcat ttcttttagg attggaataa
    44401 agtttagcga tttcggtagt tgctccccat gtttcgccaa cagtcatcag atttttgtca
    44461 ccaaaagttg cttgattcat ttcctgaaga tactcatgca gtttaggtcc attacttgtg
    44521 atttctttat ccggttcttt gccaatcata tcgatcacgt ccatacgaaa gcccccaata
    44581 cctttatcga tccagaaatt catcatttga taaatctctt ggcgaacctg tttatttttc
    44641 caattcaaat caggttgacg cttgctatac aagtgcagaa aatattgccc cgttttttca
    44701 tccaactgcc aagcagaacc actgaatatt gagcgcaatc tattaggctc ttttccattg
    44761 accggatcac gccaaatata atagtcccga taaggatttt ctttattttt acgggcctca
    44821 atgaaccacg gatgttcatc agaagtatga ttcaccacca gatccatgat gatacggata
    44881 tttcttttct ttgcttcttc aatcagttct tccatttctt ccatcgtacc gaattctgcc
    44941 atgattgctt gataattact gatatcatac ccattgtcat cattcggaga ctcgtatact
    45001 ggagaaagcc aaattgcatc aatacctaaa tacgccagat aatccaacct ggaaataatc
    45061 ccccgcaaat ctccaatacc atcttgattt gaatcttgaa aacttcttgg atagatttga
    45121 taaacaactg aatggtgcca ccatttttgt tccatgattt tcctcctata aatggatgtt
    45181 tctatttttt gcttaatcat ttattttagt ctctctcact aaaaattgta acgctttcaa
    45241 atagctattg caccttgtta tcggtaacag aataaaacaa aaaaacagct gaggaaattc
    45301 cctcaactgt tttttgaaag gattgattta tgcagggaag aatgctgatt tcacaacttc
    45361 tttataaacg gtgttcactc agctgtccct tggtattagc tcaaaaaacg gcaaaatata
    45421 agaaactatt ttttcgtttt tttctctaat actcaggcca gaacgctgat ttcacaacct
    45481 ctttatttca cattcaatat ccacatgaat cccacaaata caaagaacag accatacatg
    45541 attggagata cttcttttcc tcttttagct gctaacatgg taattggata gaagataaaa
    45601 cctaatgcaa tcccatctga aatactataa gtcaaaggca tgccgatcaa gatcaagaat
    45661 gaagggatcg caatctctaa gtttccccat tcgatttgtc gcaaagattg tgccatcaat
    45721 actcctacca taatcaatgc tggtgcagtt acttgtgaag taacaactga tagtaatgga
    45781 gaaaagaaca agcctaacaa gaagaaaatc cctgtagtaa tagctgtgat acctgaacgt
    45841 cctccaacgg cgataccagc tgatgattct acaaatgcac caacaggaga agtaccaaat
    45901 aaggaacccg caagcatagc tgttgaatca gaagctaaag ctttccctac acgaggcatc
    45961 ttgttgtctt tcatgaaacc tgcttggttt gctaatccaa ctaaagttcc tgctgtatca
    46021 aagaaagtca caagcaagaa tgtcagcact acgacccaca tttgaagaga attgatgtcc
    46081 cctacatgtt ttaatgcaac taaaaatgtt ggtttcaaac ttggtgctgc ggcaacaatt
    46141 tcagaaggca ttggaatcaa acctgtgacc agacctaaaa tcgttgtagc tgccatcccg
    46201 atgaagatgc cacctggtac acgccgaaca agcaagatag cagttacgac taatccaaaa
    46261 atcgtcaacc aagtagaacc aacgttgagt gatcctaatc ctactaatgt agattcattc
    46321 gaaacgatga tcccaccttc gctcagacca aggaaagcga taaatagacc gataccgcca
    46381 gaaatcgcat atttcaaatc tgctgggatc gcatcaatga tcatttcccg cagcttgaag
    46441 attgtgatca aaataaaaat caaagaagca acgaatacgc cggctaatgc tgtttcccat
    46501 ggaatcccca ttcctaaaca aacagaataa gcaaaaaaag cattgatccc aagagcaggt
    46561 gccgttccaa ttggataacg ggctaatacc cccattaaaa cacagccgat cgcactggct
    46621 aatgcagtcg cagtaaacac tgctccttca tccattccag aagcacctaa tacagttgga
    46681 tttacaaata agatataagc cattgagata aatgttgtaa atcctgccag tacctcacgt
    46741 tttaccgtgg tgttcaattt ttctatttcg aagtaggaaa gtattttttc cttcatcttc
    46801 catcccccta aatccgaaca ttataaataa agtccgttaa aatttcgatt tattaataaa
    46861 acaacgtgtt ttatcatata ctaaaacaaa acataagtaa acaaaaaatt cggattttaa
    46921 gcaaaatccg aacgttccat ctgattaaat ccctttatct caaagttcat gaacattcac
    46981 tttggattac aagaatttct ttattgtgtt aataaagttt cttcattcta gtctcaaaaa
    47041 tcaatagtgt gatttgattt taccatttcg tttctgttct tctttgatga attcttttgt
    47101 atcgacagga ttcagattat ttagtccgcc aaaacctgta tcgaccattt ttccccagcc
    47161 ttttgtcttc ttttttcctg atttgagatt ctttgctcga agcttctcac tatgttttgc
    47221 tcgccgatac ttcaaataac cttctaatct tcccattaga tccactgttt ttcctccttt
    47281 ttattcaatc agacgactca gcttttccta taacaaaata attgccttca gggtcagaaa
    47341 aattgaaagt caagatgcca ttgttatctg tgatttctcc tggttcttcc atgttctcgt
    47401 agatagtttc aaattcatcc gtaaaaaata ctaaagaagg cggtggtcct aatacctctg
    47461 gtgaaaactt ctgcacaaat acttttggga atacgcctaa ttctaattct tttgagatgc
    47521 tgagtacaat actcttaaat tcttctggca attcgattgt ttcagaaatt tctgcaccaa
    47581 ttttttctac aaagaatcgg caaatcatct ctacgtcatt gacataaagc atcacacgtg
    47641 ttttttgtat catcatttga cccttctttc tatttgattt tctttcctgt ctataaactg
    47701 attccattat atcacgaaag cgcaaacacc ttgtgtttga tactattcaa gaaaaataaa
    47761 gcaatagttt ctaggattgc tttcctccac aaactttttt tacaaaaaaa aaacggcaat
    47821 gaatgccgct cttcttattt cgattctttt ataattctgc ttctgattca tctttggtta
    47881 gtgtgtgtct aacactagtt acgccaaatg tttgatcgat tttttccttc aacgcttcga
    47941 ttgcctgtgc gccacgtgcc gcttgttcag cattgatgga ttcaatgacc agcaccgctg
    48001 cttgtgtttc ttccgtcagc atcgttcttt gggcttcacg ccagttgaga cagcgacaga
    48061 tcgctccttg ttcatcatag tagatgattt cttccggaag tgccggagca tcggaatctg
    48121 cacctaaagg caggaatgat tcgccacctt gggcttttcc taaatgcaga tttcctgcga
    48181 tcttttcgat atcttctccg ccgcaaggta cgccaaaaga caaggaaata ctattataga
    48241 tatctacaag cggattgatt gggaaaaatt cccgttcttg atttgcacgt ttcagtaaag
    48301 cttcaataga agaacgtgca ccttttttag tcttgaatgt ggtaaatgcc tgacgccact
    48361 gagcaatgac ttcgttttgg ctgaatgttt cttctgtaag gtaatttctt gcttcttttg
    48421 ctgcctcatt caataattga tgatacgttt cttcactttc ttttgttacg tggttatcga
    48481 taccatttac ggataagatt tcgatggttg cttcaggaaa tacttcccag aaattggtat
    48541 ccactattac ttttttcatc tgttcacacc tcttgattag aataattgct tgatgaatag
    48601 atagtctgtt tggggatcat ctcccatata aaaaacatgt tcgctgtatt tgataaatcc
    48661 ttttttacga taaaaagcga gcgcaacatc gttgtgttcc caaacaccga gccaaatggc
    48721 tgttttttgc ttttcttttg ctttttcaat agctgtatct agtaaaaatg taccgatacc
    48781 ttgatgttta aatttttttc gtacatagat tcgctcgatt tctaaaaaat gatcagccat
    48841 ttcctcagat tgactcgttc ctgtatttag tttcaggtaa cccgcaggct cttgatcgat
    48901 actcactagg aaaaaatcgg tttctttatc ttttagctct tctgtaagtt tttctagtgc
    48961 ataagcttgt gtcaagtaat cagctaaatg ctccggtgaa ttatcttttc caaatgtatc
    49021 tgtaaatgtt tcgatactaa tttgttgtag taagtctaca tctgaaggcg tcatttttcg
    49081 aatttcgtat ttattcacgg cttcttcctt tcaatagatc cttttattgc cttttttgac
    49141 aaaattccaa tcttcgctaa cattcttgca tactttattt aaaagatatt ccaattgttt
    49201 tgcttcttcg tcagaaagac catttaatgc gactgcattg gagtagttgt tttctcgaat
    49261 gatgaaagga tagatttctg ctcctttttt agtcggatag agtttcttga tttttttatt
    49321 ttctttatct tccaaacgtt cgatcatccc attggattct aatttcttga ttgctcgggc
    49381 agtcgttgta cgatctactt tgatcatttc tgctagtttt tcttggatga ttccaggatt
    49441 ttcgcaaata cgtactaaat aaagatactg tcctcttgtt aaatcgactt ctttgaattc
    49501 gatattgcta atagaatcta gcgctcgggc aatcattccg atgtctcgaa ggatttcagc
    49561 catttcatcc cacctttatt ttgtttgtaa gactagttca cctctttttg ttgcaaatgc
    49621 aactattttc aataaaaaaa tcaagttctt ttttaataac tagtaaagta tattcttttc
    49681 ttcttttacg aaaaagctca atcacaatag atctggtttt tgttttctaa aataagtaac
    49741 tgtttcttcg ttgttcgctt ttctgatagc tttggcaact cttctatact aaaaaatccc
    49801 atgttggaag tttcattatt ctcaataaac ttggcctctt caccgtggat cgcacaagca
    49861 aaaacaagtt tataatactg aaaaagctgt ggaatatctt tttgtttatt cgtatcaaaa
    49921 actgctcgca actgagtagt ttctactgtt aatcctgttt cttcatagac ttctttacgc
    49981 acattttctt caggagacaa tcctatttca gcaaatccac caggaagtga ccattctttc
    50041 gtccgtttat cttcgattag taggaccttg ccatcttttt tgatataggc acgaacatct
    50101 acttttggtg ttggatgtcc ttctccaatc gttgtgagcg cttttatttc ttcgaaagtt
    50161 tcttttccta tttcactgat cagttccaat gaaatcgtcc ggatctcctc aaaacgctct
    50221 ttatcaaata catcttttcc ataatataga ccagcttgag aaagtgcgag tagtcttttg
    50281 tattgagcca acttcttgtt cattctcttc ccttcttttt tagcaaatgt atgactatgt
    50341 aatcaagtat agaagactgg tttaattacg gcaaataaat ataatgaaat ctgcaataaa
    50401 taaaagaatg ttaaaaaact cgagaacaaa agacattcga cttctctggg gctgtgaata
    50461 aatggcgttc aaaagcttgc atctgcggta ataagcccca ccaaacgaaa aatatgacga
    50521 gctattcttg tctggctgtt cttattaatt gaggcaggac agctttttca caacctcccc
    50581 actaaacggt gttctcctac caactcctcg gtcacaagtc acaatattca tcaaacatga
    50641 gaagctgttt ttttgaaatt gctccttgtg actcggagct gaacgacagg ctcacgacct
    50701 ctcggtaaac agcgttcaaa agccaatttt tcgatattaa gccatttctt tgttacttat
    50761 tgtcattgat ttctttttct aatttatcca atagtggagt gtaatccact tgagtatagt
    50821 ctgttacatc aaattcatat agtgttccta actggaattt gtcatatttt cggtcggcga
    50881 tgatcttttt gaatgcttct ttcgtaatat gattggtccc tttcgttcga tcttccaata
    50941 cgtcaccata gtgataatga tccatgatat agctcaaatg acgatctgat tcacgatcac
    51001 gtttgtaccg acgttgccat aacacttcaa agtctgctgt taggcgaatc gtgatcacct
    51061 gatatccgta tctatctgct aattcttgga gtcgtgcttt ttgcttatca ctaaaaggat
    51121 actcggacac aatcactttc tttcctgctt ccatatacaa atcaagtgct ttgtaataga
    51181 aaggataaac tttcgtcctt tcttgttccg cccgttcttc caaattgtta aacccgatgg
    51241 attctgcata gtattccttg atttcatcga gcgtgatggc atacatatct ggaaatcgtt
    51301 cccgtagttt attcataaga tatgtttttc ctgtaccagg actaccagcc agaagaatga
    51361 aatacttttt catctcattt atttcctaag ttaattggac tttccaagtt cataaacagt
    51421 ccaatcttat gcttgacaat ttcttttact gcttcatttg ctggaatcac attatggcga
    51481 agagacttgt tgatttctgt ttcactaaag gtttctttag ctactttcgt ccagttgact
    51541 aaaagctccg ttccaacatt gaatttgcgg atcccgttat tgatcaattc aggataatct
    51601 tcttctttca cacctgttcc tccatggata actaggggga catcaactac tgcatcgatt
    51661 tctttcagca agggaatgtt tacttctgtt tttgatttga attgtccatg attcgtaccg
    51721 atagcaatag ctaatgcatc cacgcctgta gcttctacaa atttcactgc gtcttccggt
    51781 cttgtatata ccttgtcatt ttcagcgaca tggattcctt cttctgtacc gccgattgtt
    51841 ccaagttctc cttctacgga aacaccgtgc gcatgggcat attctactac tgcttttgtc
    51901 ttcaggatat tttctttgaa aggcagatgg gacccatcat acatgacaga agtatatccg
    51961 ctgtcgattg cttctttgat atcatcaaag tctcgggcgt ggtctaagtg caagactgca
    52021 tcaaccattt cttcttctgc aatagctgtc attacattga ctaacacatg catgccgata
    52081 tatttagcgg tatcgacact tgtttgaata atgatcggcg aacccatttc ttttgctgcg
    52141 cctagcatag caggaagcat ttctaggtta tgcgtattaa aagctccaac tgtaaaattc
    52201 aactcttctg ctgtttttgt tacttctttc aatgttgtat acatctttta ttgccacctt
    52261 atctttttat ttgtttcctt tgatcgttac ttgttttgca atttgtcgca tctcatccat
    52321 tttgcccatg tagtaatcga tcccttgatc atcaccagca cgagcagcat ctgcacgctt
    52381 ctggttatag aggctcatca gttttttata cccatctccg atcgtctgtt tattttccaa
    52441 actcttttct aaatattgga tggcttgatc gttcacatac aattcagaaa atttaagtcc
    52501 aacttgttca taaagtttcg ctaatttatg cttatcttgg gtagtggaaa tctcttgttt
    52561 caattgtgta atctctgatt gaatcttttc ggtcgcttct ggcgataggg ctttttcttc
    52621 ttttgccaga acttttttcg gttctttttc ttttttctta aaaaatccaa acatcatttt
    52681 ccctactttc aattaaaatg ctttcaaaac tgggcttaag atccaggcat ataagagtgc
    52741 tgcggctact gtatctacat cggttgctgt agcattgttg aatcccatcg aattaaagat
    52801 cgttactagc aaagcgggca ataatgtaat aaagaaacca tgagcaatac cgccaatgat
    52861 cgctcctcgg cgtccgccaa ctgcgttgcc aaatatccct gctgtccctc cggcaaagaa
    52921 attggttagc ataccaggta aaatcatcgc taagccgaac atgggcaaag taaacatggc
    52981 aataatcgta ccaatcgttg tcgtaatgaa acctaaaatg acagcatttg ggctataagg
    53041 aaagaaaact ggacaatcta aggcagggat cgcatcagga actaatttca tagctatccc
    53101 tcgaaatgcc ggcacgattt cacctaacag tagacgtaca ccagctagca atacatacac
    53161 acccactacg aattggatgg cttgtaaaaa ggcaaacatg atatagtttt gatctcctga
    53221 taattcagaa gcgaatggtt cgcctgcaaa taaaacagtg atgatatata gcgggaccat
    53281 cacgaccatg acagacaaat aagtatcttg cagaaattcg aaatgtgtcg gcaacttgat
    53341 atcttcgatc gactttttat tttcgccttt ctcaccaaaa agcttagcaa caccggcttc
    53401 aaataagtac ccgatcgtac aaaaatgacc taaagcaata tcatttgatc cagtgatttt
    53461 acgaatgatc ggttgcgcta ctgccggcat agcaatggcg aaacaagctc cgataaaacc
    53521 accgaccaag atcaatacga tccctcgcag accggcaaaa tagccaaaga ctgtcgtcat
    53581 cgttgccatc cataaaattg cttgaccagt taaaaaaatg tacttccatt ttgtgaaacg
    53641 agccaaaata atattgaata caaaaatggc taagaacgtc agtgcaatat ctctacctaa
    53701 acccaaatca ttcattgctt gaccattgat agattcaata gaagggatga tcccttgcat
    53761 atgaaatcct tcagtaaaga ttttcccgaa ataagttaaa cttccaacga tgatgctcga
    53821 accggcactc aacacttgaa atcctaggag tgtctttaac gtgccagaga tgacttgtcc
    53881 tgctgatttc ttctgcagta gtagacccaa catagcaatc aatgcaatgg tgatcgatgc
    53941 ctgagtcaaa atattttcga tgataaaatt gataacgccc atgttttgat gtgcacccca
    54001 aaagttagac tagaaatcta attaaaaggg gtgctttttt tgcggaaata tacatttgtt
    54061 tttaagaaaa aagtagtttc agactattta aataacgaag gcggctacaa atatcttgca
    54121 cataaatatc aaataaatcg tacactggtt agacattggg taaggattta taactatcat
    54181 ggttgggaag gcttggttgg aggtggcaaa agctacacta caaaatttaa acttgatgtt
    54241 atagaatata tggaaacaaa tggtctttct atccaagaaa ctgctaaaaa atttaatatc
    54301 ggttcaaata gaactctaag taaatggata gagcaatatg aagaaggcgg tgcttcttca
    54361 cttgagagcc aaaaaagggg cagaaaaatt agtatgaatt ccaagctaaa cattcctaaa
    54421 aaacttaaag atgagtctct tgaagaagaa gttattcgtt taagagcag
//
LOCUS       DAZULR010000018        53491 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.018, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000018 DAZULR010000000
VERSION     DAZULR010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 53491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53491
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.018"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            44..1411
                     /gene="nhaC"
                     /locus_tag="ACG8ZV_001177"
     CDS             44..1411
                     /gene="nhaC"
                     /locus_tag="ACG8ZV_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HFS4996529.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(1692..2711)
                     /locus_tag="ACG8ZV_001178"
     CDS             complement(1692..2711)
                     /locus_tag="ACG8ZV_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFS4996530.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(2733..3740)
                     /locus_tag="ACG8ZV_001179"
     CDS             complement(2733..3740)
                     /locus_tag="ACG8ZV_001179"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFS4996531.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            complement(3733..4398)
                     /gene="pgmB"
                     /locus_tag="ACG8ZV_001180"
     CDS             complement(3733..4398)
                     /gene="pgmB"
                     /locus_tag="ACG8ZV_001180"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HFS4996532.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQTGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            complement(4391..6685)
                     /locus_tag="ACG8ZV_001181"
     CDS             complement(4391..6685)
                     /locus_tag="ACG8ZV_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HFS4996533.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            6945..9110
                     /locus_tag="ACG8ZV_001182"
     CDS             6945..9110
                     /locus_tag="ACG8ZV_001182"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIBC"
                     /protein_id="HFS4996534.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            9414..10247
                     /locus_tag="ACG8ZV_001183"
     CDS             9414..10247
                     /locus_tag="ACG8ZV_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HFS4996535.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(10349..12049)
                     /locus_tag="ACG8ZV_001184"
     CDS             complement(10349..12049)
                     /locus_tag="ACG8ZV_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996536.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            12556..13716
                     /locus_tag="ACG8ZV_001185"
     CDS             12556..13716
                     /locus_tag="ACG8ZV_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFS4996537.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            13732..14175
                     /locus_tag="ACG8ZV_001186"
     CDS             13732..14175
                     /locus_tag="ACG8ZV_001186"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4996538.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(14658..15188)
                     /locus_tag="ACG8ZV_001187"
     CDS             complement(14658..15188)
                     /locus_tag="ACG8ZV_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HFS4996539.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            15293..15844
                     /locus_tag="ACG8ZV_001188"
     CDS             15293..15844
                     /locus_tag="ACG8ZV_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFS4996540.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            complement(15997..16470)
                     /locus_tag="ACG8ZV_001189"
     CDS             complement(15997..16470)
                     /locus_tag="ACG8ZV_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFS4996541.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            16608..18080
                     /locus_tag="ACG8ZV_001190"
     CDS             16608..18080
                     /locus_tag="ACG8ZV_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HFS4996542.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            18077..18787
                     /locus_tag="ACG8ZV_001191"
     CDS             18077..18787
                     /locus_tag="ACG8ZV_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HFS4996543.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            19139..19423
                     /locus_tag="ACG8ZV_001192"
     CDS             19139..19423
                     /locus_tag="ACG8ZV_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HFS4996544.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(19704..20123)
                     /locus_tag="ACG8ZV_001193"
     CDS             complement(19704..20123)
                     /locus_tag="ACG8ZV_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HFS4996545.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(20125..20709)
                     /locus_tag="ACG8ZV_001194"
     CDS             complement(20125..20709)
                     /locus_tag="ACG8ZV_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HFS4996546.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(20756..22231)
                     /locus_tag="ACG8ZV_001195"
     CDS             complement(20756..22231)
                     /locus_tag="ACG8ZV_001195"
                     /EC_number="4.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HFS4996547.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            22412..22723
                     /locus_tag="ACG8ZV_001196"
     CDS             22412..22723
                     /locus_tag="ACG8ZV_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996548.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(22838..25174)
                     /locus_tag="ACG8ZV_001197"
     CDS             complement(22838..25174)
                     /locus_tag="ACG8ZV_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HFS4996549.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            25316..25984
                     /locus_tag="ACG8ZV_001198"
     CDS             25316..25984
                     /locus_tag="ACG8ZV_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFS4996550.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            25987..27030
                     /locus_tag="ACG8ZV_001199"
     CDS             25987..27030
                     /locus_tag="ACG8ZV_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFS4996551.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(27267..28148)
                     /locus_tag="ACG8ZV_001200"
     CDS             complement(27267..28148)
                     /locus_tag="ACG8ZV_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFS4996552.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERALRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            28307..29035
                     /locus_tag="ACG8ZV_001201"
     CDS             28307..29035
                     /locus_tag="ACG8ZV_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HFS4996553.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKSCGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            29191..29508
                     /locus_tag="ACG8ZV_001202"
     CDS             29191..29508
                     /locus_tag="ACG8ZV_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFS4996554.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            29501..30109
                     /locus_tag="ACG8ZV_001203"
     CDS             29501..30109
                     /locus_tag="ACG8ZV_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HFS4996555.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            30164..30955
                     /locus_tag="ACG8ZV_001204"
     CDS             30164..30955
                     /locus_tag="ACG8ZV_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="HFS4996556.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            31093..31581
                     /locus_tag="ACG8ZV_001205"
     CDS             31093..31581
                     /locus_tag="ACG8ZV_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HFS4996557.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            31632..32504
                     /locus_tag="ACG8ZV_001206"
     CDS             31632..32504
                     /locus_tag="ACG8ZV_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HFS4996558.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            32680..33042
                     /locus_tag="ACG8ZV_001207"
     CDS             32680..33042
                     /locus_tag="ACG8ZV_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFS4996559.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYIQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            33051..33803
                     /locus_tag="ACG8ZV_001208"
     CDS             33051..33803
                     /locus_tag="ACG8ZV_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4996560.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            33817..35619
                     /locus_tag="ACG8ZV_001209"
     CDS             33817..35619
                     /locus_tag="ACG8ZV_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4996561.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            35896..36936
                     /locus_tag="ACG8ZV_001210"
     CDS             35896..36936
                     /locus_tag="ACG8ZV_001210"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFS4996562.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(36988..39132)
                     /locus_tag="ACG8ZV_001211"
     CDS             complement(36988..39132)
                     /locus_tag="ACG8ZV_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFS4996563.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(39489..40862)
                     /locus_tag="ACG8ZV_001212"
     CDS             complement(39489..40862)
                     /locus_tag="ACG8ZV_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFS4996564.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(40862..41257)
                     /gene="rbsD"
                     /locus_tag="ACG8ZV_001213"
     CDS             complement(40862..41257)
                     /gene="rbsD"
                     /locus_tag="ACG8ZV_001213"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016872 - intramolecular lyase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HFS4996565.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(41285..42202)
                     /gene="rbsK"
                     /locus_tag="ACG8ZV_001214"
     CDS             complement(41285..42202)
                     /gene="rbsK"
                     /locus_tag="ACG8ZV_001214"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006014 - D-ribose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HFS4996566.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(42310..43323)
                     /locus_tag="ACG8ZV_001215"
     CDS             complement(42310..43323)
                     /locus_tag="ACG8ZV_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HFS4996567.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     NNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(43404..44006)
                     /locus_tag="ACG8ZV_001216"
     CDS             complement(43404..44006)
                     /locus_tag="ACG8ZV_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HFS4996568.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKGIVNNGTLSPHTAQSILTNN
                     DLLAKTLKRTAALKVLVNVDITTFSYLSHQTDAGGISALSAPAEFTDLLLKDSLKDTN
                     NMLTITNYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLA
                     EDACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            44191..44892
                     /locus_tag="ACG8ZV_001217"
     CDS             44191..44892
                     /locus_tag="ACG8ZV_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4996569.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            44902..47613
                     /locus_tag="ACG8ZV_001218"
     CDS             44902..47613
                     /locus_tag="ACG8ZV_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFS4996570.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANIGNGSVDYFVYLPESAFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKITEGKAQIAQGRTQ
                     LEDAKKQLAQQSAAIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKAAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            47959..49587
                     /gene="treC"
                     /locus_tag="ACG8ZV_001219"
     CDS             47959..49587
                     /gene="treC"
                     /locus_tag="ACG8ZV_001219"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HFS4996571.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(49647..50828)
                     /locus_tag="ACG8ZV_001220"
     CDS             complement(49647..50828)
                     /locus_tag="ACG8ZV_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFS4996572.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            51080..52603
                     /locus_tag="ACG8ZV_001221"
     CDS             51080..52603
                     /locus_tag="ACG8ZV_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HFS4996573.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(52672..53400)
                     /locus_tag="ACG8ZV_001222"
     CDS             complement(52672..53400)
                     /locus_tag="ACG8ZV_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFS4996574.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
BASE COUNT        16721 a         9607 c        10925 g        16238 t
ORIGIN      
        1 tttttcatgg cagggccttt tcatttgaaa taggagatcg acgatgaata aaaatatttc
       61 tttaaaagaa agtatcgctg tattgatcgt gttgttggca ctcctaggag tactgatcat
      121 cggattccag ctctcgccac atatcccgat ccttgcagct ttcatgtgtt tgttgtttta
      181 tggcagattt aaaaagttca catgggatga gatccatgac gggatcatca aaggaatcac
      241 tccagggatc attccaatcc tgatttttct tttgattggt gtcttagttg cttcatggat
      301 tttatctgga accatcccta cgattatggt ttatggattt aaacttgttt ctgtgcgttt
      361 ctttttaccg acagcatttc ttgtttgtgc aattgtcgga gtgactgtcg gcagttcatt
      421 tacaacgatt tcgacgattg gaattgcttt tttggggatc ggtcatttac ttggattcaa
      481 tgatgcaatg actacaggcg cagtcgtttc cggtgccttt ttagggaata actgctcgcc
      541 tttatcagat acgaccaact tggcagcggg tattggagga gttaatctat tcgaacatat
      601 cgctggtatg cgttatacgg atttcccagc attcgtcctt tcgttgattt tttatacgat
      661 attaggacat aacagtcatt cagccgatct agctagtatc aatgaaatga tccaaaacat
      721 gaaagcgagc ttttggatct ctccttggac attgattcca ctagttattt tatttggggg
      781 ggcaatcaaa aaaattccgg ctatccctac attactagcg ggatcgacag ctgctctcgt
      841 tctttctttt atccatgaga aaagtttgac ggtcggaaaa gcagcagaca tcttgatgaa
      901 tggttatgtc gcaaatacac ctgatccaaa gctagatgaa ctgctttctc gaggcgggat
      961 catgagtatg ttaggttctg ctagtttgat tttacttgca ttggcattag gtgggttact
     1021 gatcaaatat ctgatcgttg ataccatcgt tcaagaatta aaagaaaaga tggaccgacc
     1081 ttctcgttta gtcgggttta ctgccttgag ctgtatcgga atcaatctga tcgttggaga
     1141 acagtatctg tccatcattc ttccaggaga aacattcaag cgttcttttg atgacgttgg
     1201 cttatcaaaa acctatttga cacgaacact agcggattca ggtgcgaccg tcaattctct
     1261 cgtaccgtgg ggagtcagcg gcacattcat tatgggaacg atgaaagtta gcgcgttgca
     1321 ttacttgcca ttcgcctttt tctcgattct tgcacctgtc tttacaatat taggcggttt
     1381 tttattgaat cgtcgacgtg taaaaaattg aaggaaggaa aaaagaggct gggacagaag
     1441 cgtttaactc caagaaataa gaagaaactc aagaaaattg ctttttaaat ttttgtgaat
     1501 ttcagcttat ttccgaagga gttgcttctg cttccgccgt ttatacgtgt ttagagcgtg
     1561 agacaaaagt gttctttact tttgtcccac gctctttttt acagataaac aatgtgttag
     1621 aagtagtatc ttcttttaca taaaaagctg accataggat aaatggtcag cgtatttagt
     1681 gagtcagcta tttagtatgg gttttctaaa ggaacgactg tctctctttt gatcaagcga
     1741 tgagggatga ccaaacgtac gccactgctc aattcttcat ggatcaattc gcgcagcttt
     1801 tgcatagcga cacgtcctaa ttcggagata tcgatatcga tacttgtaag gtaagggtgt
     1861 gttaatgttg agaagatcga gttgttgaag ctaatgacgg agagtgtctc tggaatgaca
     1921 tagccataca tttgcgccaa ctgcatcgtg cgaagggcga agatatcgtc aatgaccacc
     1981 aatgctgtgg cttcgttttc tttcaacgtt ttctcaaagg acagataatc ctccggatgc
     2041 tctagtacta cactggataa cgcaggaaga ccagccatca tcattgcttt ttgataaccg
     2101 aaatatcgtt cgaaatacaa actttcatga gtcgtgtttg tcacaaacag gatattctta
     2161 tgtccattct ggatcaaaaa ttctgttgct tgtttaccta gaagctggtt atcattatct
     2221 acataaacga tttcgttctc atgatgataa ggctgtccga tcaaagtgaa agggatgtgg
     2281 ttttggtata aataatcaat gacagtatct tgactatctg aatacactag aataaaacca
     2341 tctacttgtt tttgtaaatg catacgctgg acgttctcta acagcaattc aaaattttta
     2401 gcagtagcga ttgctgtagt catatcataa ttccgcgctt cttcgttgat tgcttccatg
     2461 atctcaagat aaaatgggtt accgatccgc tcttttgaat caagaggggg taagattacg
     2521 ccgatggcac tggaaatgcg ttttcctaga ttgcgggcag tcatgttagg aacataacct
     2581 agttcatcca taatttttcg gactttcttc tttgttgtct cggaaatact aggatgatcg
     2641 ttgatgacac gagagacggt cgaggtggca acaccggctt ttttcgccac atcttttacg
     2701 gtaatagcca tgataaaaac acctttctct tgttattgtg cagagaaccg ataaatcgtc
     2761 tgactgatcc gttcttgacc aggatggagg ttgatcgatc caaatttggg gaaatgaacg
     2821 atatcaggga tttcttgcgg ttcgattgct aatccgtagt ttgaatgcat ctgttttcca
     2881 ttgacagaga aatcagcttc gaatccagtc gtagaaaata ataccatact tttattagaa
     2941 gttgctatag tcatttggcg accagaatgc ttctcgaata attgtaagga agttttggaa
     3001 agcctaggat gatgcaaaag aaatacatca tctagtccat ctggataaca tgcaaggatc
     3061 tcttgcagtg ttggggattt tctaaagtcg attggcagtt tttctttttt tgtccaattt
     3121 ccagtaggca gtttttcttg atctaattca agcacaccat ctaaaaagac cgttaactga
     3181 tgttcataga tgtctcttgt tccatttcct gaaaggttga agtaggcatg gttggtcgga
     3241 ttgcagatgg tttcaacaag gctactagca gaggttgtca tctctaattc gttttttgtt
     3301 aaacggtaag tgatcgtagc agtgattggt cctggatagg tagaaaattc atcttttaag
     3361 taaaagacca cacctattga tgatggagtt ttgaaaactt ctacttccca aaattggaaa
     3421 gaccagcctt tcgtgccacc gtggatatgg tgtgatccgc agtttttctc caatctatgc
     3481 tcaccccaag aagcatcccg gatccttccg gctacaggtc cgacagttgc tccaaaaaag
     3541 cttttgtctg ttagaacatc ttcgaaacga tcgtaagaca ataaaacatt ttctgatttt
     3601 ccttctttgt ctggtgcgaa gatttggtgc aggcgggcac cgtaattgag aagaacgact
     3661 tctaagtagt cgttcttcaa tgtgattttc tttatttcag tctctggaac tggtacgacg
     3721 gagatctctg gattatccat ggtcatgcca cttttctttc aagtaatcga tcgtaagaaa
     3781 agtcgtatca gggacaagcg ggatctcctc tccaaggtct tcagcacgtc ccacgccaat
     3841 tggttgagcg ccacttgaga ggatggcttg gataccggtt tgcgcgtctt cgatcccgat
     3901 acattcttct gcttttagtc cgacagcttt tgctgcaagg aggaagatat ctggcgcagg
     3961 ttttccgttt gttgcttctg ccgggtcggc aatagcatca aagtaaggtg taagacccat
     4021 tttttcaagt aggaatggcc cgtttttact tgcagaagca agagcaatct tgattttttc
     4081 ttcttttaaa gaatccagta aaggcacgac cccggggaag acatcttttg gttcgatcgt
     4141 ctggatcatc tctaaataat aatcgttttt tcttttcgct aattctgcaa attcttcctt
     4201 tgaaaaagag tgttcttttc cgccataagc taaaagcaaa gagagtgagt cttctcggct
     4261 gacgcctttt agctgttcgt tgaatgtgtg gtcgatcgta atgccgattt cctgaccaag
     4321 ctttcgccaa gcacgataat ggaattcagc agtatcggta atgacaccgt ctaaatcaaa
     4381 caatacccct ttaaacattt gcttcctcct ttcttagcgt tatttctaga cgatccgcta
     4441 aagaataaga ctgttcatag acgtaaattt ctagaggaga accttctaat aactcgaaag
     4501 taacttgttc atctgtgact gagatgaaca ataaacgtcc gcgataattg atatggaaag
     4561 aataagcttt ccaagttttt ggcagaaatg gtgcgaatct caactgatca tgggcagttt
     4621 tcatttgagc aaatccttgg acaatcgaca accagctacc agtcatggaa gtgatgtgca
     4681 agccgtcttc tgtgtcgtta ttgtaattat ccaaatccaa gcgagctgtt cgctggtaca
     4741 tttctacagc tttgctttcc attcctaatt ctgctgctaa aatcgaatgg atacttggcg
     4801 aaagggaaga ctcatggaca gtcattggtt catagaaatc aaagtttttt tgcttttctt
     4861 cttttgtaaa agtatcattg aagaaataaa tcccctgtag tacatctgcc tgcttgatga
     4921 agcaagatct aaggattttg tcccaagacc aatgctgatt cagaggaaga tcgcttgtgg
     4981 gaatatcgga tacaggcatg agatctttat ctaagaatgt gtcatgctgg acaaagattc
     5041 ctaattcttc gtcaactggg aagtacatgt tctctgcgat atctttccat ttggctagtt
     5101 cttcttcgct gatagtgata gcagcttctt tttgataagt taaataattt tctcgcgtgt
     5161 aacgcaagac ccaagctgcg atcgtatttg tataccaatt gttattgata ttgttctcat
     5221 attcgtttgg gccggtcaca ccgtggatca tgtatttatt tgctcgtttt gaaaaatgga
     5281 cacggtctgc ccagaagcgt gcgatttctg ctaaaacttc cagtccttca tttttcaaat
     5341 attccgtatc gccggtgtaa ttcgtataat tgtagattgc ataggcaatc gcgccatttc
     5401 ggtgaatctc ctcgaatgtg atttcccact cgttatggca ttcgacacca gtgaaggtga
     5461 ccataggata aagcgcgcct tttaatcctt gttgctgagc gttgtggatt gcttgcggca
     5521 gttgattatg ccgatatttc agcagattct tagttacttc aggtttggct aaagcaagat
     5581 aaagagggac agcatacgct tctgtatccc agtaagtggc tccgccgtat ttttctcctg
     5641 tgaatccttt ggggccgata ttcaatcgtt catcttcgcc gtagtaagta gagaatagtt
     5701 ggaacaaatt gaatcgaata ccttgttgtg cttcttcgtc tccttcgatg accacatcgg
     5761 caagcttcca tcgttctgcc caagccgctg tttgctcttc ttttgcttgg atataattgt
     5821 ttgtctggtt cgttaattct gagacagctt tttctgcttg ctgcgcttct ggaatatctc
     5881 tactagtaag aacgataatt tctttttcca ctgaccatgt ctcaccttga gataattctg
     5941 cagacaagca accatgtaat gctaaagtat cttcgtgata gtcagggatg actgattttc
     6001 cattaacgaa atggcgcatt gctgcagtaa cagtaaattg ttcaatccca aagttgtttg
     6061 gaatagtttt agtcgtcaaa tagccgattt cttctatagt tccacgatca atctcattcc
     6121 aaaaatgttc atcatagttg ctgtcttcgt tttgaacatt tccatccaat tttgatacga
     6181 gtttgactgt tccgctacct tcaagcattt ctatagttaa atagatataa gctgattctt
     6241 ttttgacaat gctcagaaaa cgttcgaagg aaatgcgtac tttattagta gaagtagtga
     6301 ttgtgaatgt acgagataat acaccatttt tcatatctaa ttcccagtaa aagtcttctg
     6361 gttccaaaga agccaagtcg atcagctgat cgttgatcga aatatctatc gcgataaagt
     6421 tcaaggcgtt gatcactttt ccaaagtatt ctggataacc atttttccac cagccgacac
     6481 gtgtcttatc gggataccag acacccgcca aataagtacc ttgatggtgg tcccctgagt
     6541 aagtttcttc aaagttcccg cgcatcccca tataaccgtt tccaatactt gttaaagatt
     6601 cttgcagtcg aagatttttt ttatctaatt gtgtcgtgct gattttccat ggatcaatag
     6661 caaatagtcg tttgatctgt ttcatttttc tcctcctaat gagctgtttt atacgttcat
     6721 aataaacgca accgattgca caagtcaata gacaaaagaa aatatttcat agaaaaaagc
     6781 ttaaaaaaat aaatttttag gagaaaatta tagaagggaa cacacgtatt ataggtttta
     6841 tagaatggta tagacagaaa aataaaaaat aaagcattta caaaaaagaa aacgcacgct
     6901 ataatacgtt taacgaaacc gattgcgtaa aggagctaaa cggaatgaaa aagatattta
     6961 gttttgagtt ttggcaaaaa tttggaaagg ctttaatggt tgtggtagca gttatgccgg
     7021 cagctgggtt gatgatcagt atagggaaat caattccctt gatcaatcct gattggacgc
     7081 cgcttgtcac aacgggcgga gtaattgaaa atattggttg ggcaattatt ggtaatcttc
     7141 atattttatt tgctttagca ataggaggaa gttgggcaaa agaaagagca ggcggagcat
     7201 ttgcagctgg gatctcattt attttaatca atcggatcac tggggctatc tttggtgtca
     7261 caagtgacat gcttgcgaat gaagatgcat ttacccacac tctgttcggt acgaagatca
     7321 tggttaaagg attttttaca agtgtattgg aagcaccagc tttgaatatg ggagtattcg
     7381 tagggatcat cgctggattt gtcggggcaa tggcttataa taagtactat aattatagaa
     7441 aattgccgga tgctttgtca tttttcaatg gaaagcgctt tgttccgttt gttgttatct
     7501 tatggtcaac aatcgtggca ttgattcttg ctgtggtgtg gccaaacgta caggctggaa
     7561 tcaataattt tggtttatgg attgcagaat cacaagaaag cgcaccgatt ctagcaccgt
     7621 ttttatttgg aacattagaa cgtttactat tgccatttgg attgcatcat atgctgacga
     7681 ttcctatcaa ctatacacag cttggcggat cgtatgagat tttatcaggc gcacaggcgg
     7741 ggacacaagt atttgggcaa gatccgttat ggttggcttg ggccactgat ttagtgaatc
     7801 ttaaaggtgc aggggatatg tcgcaatatg agtttgtgtt gcataactgg acgccggctc
     7861 gtttcaaagt aggacaaatg attggttctt caggtatctt gatgggaatg gcttttgcga
     7921 tgtatcgtaa tgtcgatcct gataagaaag caagatataa atcaatgtat ttttcagcag
     7981 cgttggctgt ctttctaaca ggtgtaacag aaccattgga gttcatgttt atgtttgctg
     8041 ctgtgccatt atatgtcatt tattcagtga tccaaggggc tgcatttgcg atggcagata
     8101 tcttgccatt gcgggtccat tcatttggga atatcgaatt gctgactcgg acaccgttag
     8161 ctatcaaagc gggtctaggt ggagatctta tcaacttcgt gttgtgtgtg atcgcttttg
     8221 gtgttgttac gtatttctta gcaaatttct tgatcaaaaa attcaacttt gctacaccgg
     8281 gacgtaacgg aaattacgac aatgacagtg aagaaaccgt tgtatctaac agcggaacag
     8341 gaacagcaga tcagcaagtg gtccagatca ttcatttgct gggaggaaaa gaaaatatca
     8401 aagatgtcga tgcttgtatg actcggttac gcgtaagtgt aaatgatcga gaaaaagtag
     8461 ggactgaaga agcctggaaa cgagcagggg cgatgggatt gatcgtcaaa gacaatggag
     8521 tccaagcagt ttatggacca aaagcagatg tcttgaaatc agatatcgaa gatctgctgc
     8581 aatcaggagc agagattcca gagccagaaa tggtttctac aggaaatgga caagcaggta
     8641 gtaagcaata cttaggtata gaacaagaac tagtttccgc agcttctgga gaagtgattc
     8701 ctttatctga agtaaaagat ccggtattct cacaaaaaat gatgggtgac ggctttgctg
     8761 ttattccaac atcaagagaa gttgttgcgc cgatcgctgg aaaagtgaca agtattttcc
     8821 ctagcaaaca tgcaattggg ctggaaacga aagatggtat cgaagttttg atccatatgg
     8881 gaatcgatac agtccaaatg aatcagccag cttttgagat tgctgtcaaa gaaggccaag
     8941 aagtaggaac aggaacgaaa ttagctgaga tggatcttga tgtgatccaa aacgaagaaa
     9001 aagatccaac gatcatgatc gtatttacaa acgataaagt agaagaagta gtgatcaagc
     9061 aattaggtac agtgacagct ggtaaagtga tcggctccat taaaatgtaa ggagaggttg
     9121 tgaaaaagct gtcctgcatc aagtcataag aacagccaaa caaaaatagc tcctcctatt
     9181 tttcgtttgg ttgggcttat taccgagaag cagcagtttg aatactgttt agtggagagg
     9241 tcgtgaaaaa gctgccctgc accaagtgat aaaaacagcc aaacaaaaaa tagctcctgg
     9301 tccattgagc ttattactga ggagttagca ggagaacact atttgctgga gaggttgtga
     9361 caaaaatttt gtcacaaccc ttttgtttcg aaatgaagac aaggagaaaa ccaatgaaat
     9421 tcatgacact caacacgcat agctggcttg agccagaacc agagaaaaaa ttgcaagaat
     9481 tagcagataa gatcctgtta gaagattatg aagtgattgc tttacaagaa atcaaccaat
     9541 tactggaatc tgaagaagta gaacctgcga agctaatgaa gttctgtccg gtaaagaatc
     9601 aagtacctat ccgtaaagat aattttgcct accgtttagt tcagctttta aaggaacacg
     9661 gaaaagagta tttttggagt tgggaaatga gccacatcgg ttatgataaa tatgaagaag
     9721 gaaatgcact gcttacgaaa aaaacattgg aaagtcaggt ccttaccgtc tcccaatttc
     9781 aaaagaaaga agattatcag acacgcaaga tcttgattgg gaaaacaaag atagatgatc
     9841 aggacatttt tgtctcgagc tgccactttt cttggtggac agataaaaaa agtggctttt
     9901 attttgagtg gaaaaacttg gaaaactact ttttggaaac tcgcgtacca ctttttttcc
     9961 taggtgattt caataatcca gtagactctc aaggttatta tactgtaaga gaaagttgcc
    10021 ttcttcttca agattcgtat gttgtcgcga atgaaaaagg aaaagcagct actgtggaaa
    10081 agaaaataga tggttgggaa caaaatacag aaaaattgcg tatagatttt attttcgtcc
    10141 ctgaaggaat gcaggttaaa aaatatcaac ggatttttga tgggatcgat agtccaatca
    10201 tcagtgatca ctacggggtg gaaatcgaat tagatgtgaa cgaataaaaa atataacata
    10261 taacataaaa aaactgatta aaataaaact ctccaaacga ttataccgtt tggagagttt
    10321 tttgatcgga tgtatttatc ccttttgcct aagcacgtaa aagcttgtat ctatgataaa
    10381 taaataaaca tagcaaggta aaccagccaa tcaaagtaag agaaagaatg aaatagaaat
    10441 agattggcgt ttgataatga agcgtgagct cgttgattcc tttttgctgc ttcacgattg
    10501 gggtcccgat atctgttact tcataatcag tcaatgtttt tccattttgc tgtagcacag
    10561 tccgatcgta gacgataaca gggatatgaa cagttttgtc cccagtgttt ttccacttga
    10621 ttgtcaaaag accgcctgga tgtgttttta taaaagttgt ttcgttttct agtatttctt
    10681 cgttataccg gtcgtattta ttgtcttttg tctccttata gattggcaga tagtcaggtg
    10741 tggttttttg gaaaacgaac aagctggtag acatatcttt gctgaagaat gttttccttg
    10801 cttcttccgg cgtatcgaat agataagtat gtcgactgac aaatgtttca ttttcccact
    10861 tttccagatg ctggtataag ttctggatcg tctgtgctga aaaaataaga atgccaaata
    10921 tacttaaaag acggaaccac ttttgttcag accactggtt cagtgaaagg gcaaggtaaa
    10981 gtagaagcaa tagcgtaaat ggcacgaaaa atcgaaatgg aaactggatc aaactaataa
    11041 aaggcacatt tttttcgatc aatgtcgtcc atggaatcaa gctagtagaa agaaaaaaga
    11101 aaacaagact tgtgtacaac acgatttttt ggaataaggt gttcttttgt tgaaagaaaa
    11161 taaaaagcaa aaaacctgat aatatcaata taggaaaggc cttagggtaa tggagccaat
    11221 aactgccatc cagatctatc gccttttgac tcatttctct gttaacaaag ggaggaagaa
    11281 tcttattccc actgtaaaca atagctaatc ctgcccaaat atttgctgtc agaacaaaat
    11341 aaagcaagac cgacttaatc agttgaagca gtgcttttcc tttttcagtc tggttaaaaa
    11401 agtaataaag ataaaaaggg atatacatca aagctaacat gatcgaagac agtaaatgga
    11461 tctgtgtcat aagtcccact gagacagcga ctttgataac agggaacttt ttatgaagga
    11521 cgaaatcagc aatagggatc atacataaag gataaaaaca agtcccccag ctagtgaatc
    11581 cttggttgat agaccagtat tgaatagaat acgtactcat gaataaaacg gctactggta
    11641 cacttaccca atttcgaaca ttgacatatc tcagtaaaat cagcatagaa aatcctgaaa
    11701 taagataaag aatgaaattt gaaagaatct gataatgaaa ccagctacct gcaagcaaca
    11761 cgatcaatcc ttgtaaataa gcgaaaaatg ggccgtaaac ggcattcacg atcctgccac
    11821 tttgctggaa tccataaagg gaaggaaaat aatggaaatc cccatattta atttgttgcg
    11881 cggcatcata gaaccgattg taatggaatg gggcatcagc acccaaaatt agtttatgtg
    11941 tgaataaatg aggcatgaga aatgccaaag caatgaaaaa aattgctaaa aatgggccat
    12001 attttttcaa ttgtcgaact cctttgcaaa ctttagataa attcatcata tatcctatgc
    12061 gagaggtagg caagaaatta gaaaattcat gaaaatattt atgaatttta caagaaaaac
    12121 ataagtgaaa gttctaagga gagaggatgc gacataagtt ttgttgcatc tccttgtttt
    12181 gaaacagaat ttttcttaat actcgaaaca aagtagcttt ttcatgacct ctcggtaaac
    12241 ggtgttcaat cagctgcttc tcggtaataa gctcactagc ctagaaaata tgagaagcta
    12301 ttttctgact agcgctctta ttactcaaag cataacgcag ttttcacaac ctcttcctta
    12361 aacggtgttc aaaagcttgc atctgcggta ataagcccaa cccaacaaaa aatatgagta
    12421 gctatttttt tgggctgtac ttattacttg atgcaggaca gctttttcac aacctcatcg
    12481 gctttcattt tctatttttt tcctgaaccc atataataaa agaaagaaca aaaaaacttg
    12541 caagggagga cacatgtgaa gcagagtaag caaaaacagt ctcgtcgact tttgtttcgt
    12601 ttgtttttat taatatgtat cgtcgtaggg ttactgatcg ctttatatcc attttatgtg
    12661 gattctttaa atagttttat tgatcaaaaa cgtatcgaac aagtacaaaa acggaccgca
    12721 gctgaaattg aagtgcagcg aaagaaaatg gaggagaaaa accaacgatt aactgaccaa
    12781 ggattcaatc ctggtactga tcctttcaat gaaaagaaca gaaatgaaag tacaacatcc
    12841 agccaattag aggaatggct gatcggaagt atcaatatac ctaagatcca attaaatatt
    12901 tcactttatg atcggctcaa tggtaggatc cttgaaaatg gagcaggcgt cttgcaagga
    12961 acctctttcc cgcttggtgg aaattcgacg cattcagtga tctctgctca cagcggttta
    13021 cctaatcgac ggttatttac cgaattagat cgtttagaaa acggagacac gtttattttg
    13081 actgttttgg gggagaaatt ggcttatcaa gttaaaaata tacaagtggt actgccagat
    13141 gacacgtctg ttctaacgat ttcagaagga gaagacttag ttaccttgct tacatgtacg
    13201 ccgtatatga tcaacacgca tcgtttgcta gtgacaggac atcggattcc ttataacgaa
    13261 tcggtaaaaa aagaagaagg aaaaggaaat caggaaagaa ccatgcggca atggtttatt
    13321 cttgcaggaa cgataatagc tgtagtcata ctgttagtgt ttatcggacg actaatctat
    13381 cagtatagat taagtaaaaa agtgcttgat ttttcattta ttattagtga ttcgtcaggg
    13441 aaaccggtaa atggtagttc attcattttg aaacataaga aaaaaacact tactagaaat
    13501 ggtgtgccgt tttcagtaca aagcgaccat catgggaaag tcaagctgga tcaattgcct
    13561 ggtggaactt atcgaatcgt ttcagctgat gatcctaaag ttgctgtttc ttttggtatt
    13621 agaaaagtaa aacaagagaa gatatacttt tttgaggggc gaaaacttgt aaaagagctt
    13681 caaaaaaatg gtttttattt taaaatcaat gaataagtaa ggagagaaaa aatgatccgc
    13741 acaacaacaa aattgtctgc caaagaactg gaatctgttc tatcgatttg gctgcatgct
    13801 aacttggatt ctcatgaatt cattccatca acttattggg agaatcaagt agaatctgtt
    13861 aggaaagctt taccagatgc agtgatttac ttagcagaaa tagatcaaga aattattggt
    13921 tttgctgggg tgattgatca gtttatcgca ggaatctttg tgaaaaggga ataccggcaa
    13981 caaagaatcg gtacgcaact aatgaaaaaa ataaaagaaa ccaataaaac actgactttg
    14041 acagtctatc aaaaaaatca atcagctatt catttctatc tttcacaagg ttttacaatt
    14101 caaacacagc aaaaagatga agcagtaaat gaggaggaac ttgtgatgaa atggaatcaa
    14161 aacgctgatt tttgatgaac agaataacga aataatgctc ccagcctaat tttttgctgg
    14221 gagcattatt tcattttgaa gtcactaatt taactgtgtg aatatgcagt tgttacaatc
    14281 tttgataaac ggtgttcaat cagctgaccc tcggtattag ctcaaaaaac ggcaaaatat
    14341 gaggaactat ttttccattt gtttctctaa tactcaggtc aaaacgctga tttcacaacc
    14401 tcttgataaa cggtgttcaa acggctgctt ctcggtaata agcccactag cctagaaaat
    14461 atgaaaagct attttctaac tagcgttctt attactcaaa gcataacgct gatttcacaa
    14521 cctcttgata aacggtgttc aatcagctga ccctcggtat tagctcaaaa aacggcaaaa
    14581 catgaggaac tatttttccg tttctttctc taatactcag gtcagaacgc tgatttcaca
    14641 acctctcttt cacaacctta ttttactcgt ttataatttt catcgaagta ttttccgcta
    14701 cggatatcat ctggcattcc atcgtatggt tcttcgctaa taacatcttc attgtctata
    14761 cctgcatcac ccatataagt gatcgtagca aattcaggaa caagtaattt tggataagtt
    14821 tcatattttt cacgagctgc ttccatttct gcgatatgtt cgttttggaa agtaacagtg
    14881 atttctggat gttcttcaac ccatttaggg aaaaagatca ttccgtgaag tttcttttca
    14941 tttggcataa agtccaatgc cacgtctgtc cctgttggct ctgtccaagt gattttgaat
    15001 acgccgtccg tcaatttaac gatatcagct tcttggtctt ttacccaacg gcctttgacc
    15061 attccgccat ggatacggta atcaacagta tggtcatttt tggcatacca ttcatattcc
    15121 caaccattgt catacgtata gataaagtga gttccaataa aatcttccaa ttctttaaat
    15181 tctttcatgt ttaagcatct ccttataaat taaaacatgt aataaactac atgttttcga
    15241 ttactcattt atgatagaat ggatttaaag atttgtcaag gagggaaaac tgatggcaag
    15301 aaaaaataca cttcgatata ttttgttagg gttattaagt aagaagaaga tgacaggata
    15361 tgaattgaat caatcgttca aaaatgaaat aggagaattt tggcaagcaa aacatagtca
    15421 gatttatcct gaacttgcaa aaatggaaga gcaaggaatc attcagcatc aagtagagat
    15481 cacaggtgaa aaattggaaa agaaagttta tgaattaaca gaagaaggga aggaacaatt
    15541 ggcagagtgg attcatacac ccaccaatga actaccggtt aatcgagacg aatttgttct
    15601 gaaattgtat ttcgtcaaag acgtgaatga tccggcatta gtagaaatta ttcagcagca
    15661 gcgtgacctt catgaagaaa aacgacttca tctattagag cgaaaaaaaa cgatctttcc
    15721 tactgaaaaa gaaaaacatg aaaattacgg acactacctg attttagcgc atgcgatcaa
    15781 tcgggaaaca gaatatgcaa attggctaac agatgtatta gaagaaagta accgaaaaaa
    15841 ataaaaaaat atccgaacag tgatggagaa ttcctttcta tatgaaagaa acgcagatca
    15901 ccgttcggat attcttatgt tcaaacaggc cttttttcaa gtatttatgt agcatctact
    15961 tattaaaaag cttggtactt aggagattag tggcgtttag agttctttta acaactgttc
    16021 gtagtcagct ttttcatcga caggaaggag cttgtaagtt aattcgtctg tctcgttgtc
    16081 atgaatgatg tacatcttag cattctcttc tttgaagtta ccgatttgta aaatcgtata
    16141 gcgttcgtcg atcaattcga tatctttgat tgcttttgaa aaaactttac ggacatggtg
    16201 cattttcttt tggcggattt ctgccttttc tgcagctttt gacaaagtaa atccgtcatc
    16261 taaatatttt ttgatcagtt ctacttttat gactgtaggt aaacgatatt ttctaggaca
    16321 attcgcatca gcttcgatcg aacgaatgaa tcccttttgt tcccaatacc ttaattgacg
    16381 tggagacaca cctacgatat cacttaattc actgatgcca acaaccaatt gatcattttc
    16441 caacaaacgt ttaagggaag ccccaaccat ttttgtcact ccttttgtcc tcttgcttcc
    16501 cttaattata tccgtattaa cttatgtgtc aagtaggttg acaaatagcg aatttaggac
    16561 taaagtattc tagtagtttc agaaaaaatt cagaaagaag gagaaatatg agtaacaacc
    16621 aacccgtaga tatttacgga aaaccatata atcggacact tttagttgtt gtcttattaa
    16681 ttggtacatt ttgtaccgtt ttgaatcaga ccttattgac gacagctttt cctacattga
    16741 tgaaagcttt cgatatttca gcgtctgatg tgcaatggtt aacgactggt ttcttgctag
    16801 tcaacgggat catgatccca ataacagcat ggctgatcaa taaattcagt tcaagaaatt
    16861 tatatctttc tgccatgacg atctttttga tcggaacgat tacttgcttt acagcaccta
    16921 attttagtac attactaatc ggtcgtttga tccaagcttg cggtgtggga gtatcgatgc
    16981 cattattgca aaatatcatg ctatctattt tcccgccaga aaaaagagga tcagcaatgg
    17041 ggatgtcagg gatcgttatt ggacttgctc ctgctttagg ccctacatta tctggttata
    17101 tcattgataa ctaccattgg cgtgacttgt ttggtatggt actgccaatc gttgttcttg
    17161 tcttggtttt agcattcttc ctaatgaaaa gtgttattcc attgtcaaat cctagcattg
    17221 atattttatc cgctatttta tcaacgattg gattcggtag tttactttac ggattttcta
    17281 gtgtaggaga tgacggctgg ggaagcttga aagtaattgg tttcttagtt gttggtgtga
    17341 ttttcatcgc cttgttctca tggcgtcaat tacatttgga acatccattc ttggaacttc
    17401 gtgtattcaa atcatctaca ttcacgattg cagctgtttt agctggtgta acaaatatgg
    17461 cgatggtagg ggcagaaatg gtcgtaccat tgtatattca aaatattcgt ggagaatcag
    17521 cattccattc tggcttgatg ttgttgccgg gtgcattgat catgggggct atgatgcctg
    17581 tgacgggtgc gattttcgat aaatacggcg cgaaacgttt agccatcaca gggatgttca
    17641 ttttgacagc ggcaactgca ccatttgctt tcttgacaaa aacgactcca gttttatata
    17701 tcgtgatcct ttatgcgatc cgtatgtttg ggatctccat ggtcatgatg ccggtaacga
    17761 cttctggtat gaatgcattg ccaaataact tgatcagtca tgggacagcg gtaaataata
    17821 cattccgtca aatcgcaagc tcgattggta cagctatttt gatcagtgtg ttgacgaatg
    17881 tgacaaaagc aaatatccca agcaaatctg tattggataa tacgccatta gcttataaag
    17941 atcaggcaat caatgccaca ctgtcaggtt accatgccgc gtttatcgta gcgatcatct
    18001 ttgggattct tggctttatt attgcctttt tattgaagaa aaaagaacct gttctaatga
    18061 aagcggggga taatgcatga ttattggagt tttgattgtc agcttgcttg cttttgcttt
    18121 aacgaacgtg ttcgctaaaa aaacatggca aaccttttta tctttgattt tcggactaat
    18181 cttcgtcgct tcactaagtt tgatcgtcgc taatttgtcc aatcactttg gaatggaaaa
    18241 agtaacggaa acaaaaacag aaaaaattgt ttccagtgct gattcccaag gagcagatat
    18301 gcttttgtat aaagctttag ggaatggaaa agaaaaagtg tatctttacc gaacaaatga
    18361 aaaacaagaa aaaccaaaag caactggtac ggataacgaa acaaataaag tagaaaagac
    18421 agacggcgat gctgaaaaag tgacgaaaac tacttattgg gaatacaaaa acgacatgta
    18481 taaattctgg ttcaatattg ctgataacaa tcacgaatat gacagccgag tgaatacatt
    18541 caaaatccca gagacatggg tagaattaag tacggaccaa gcagccaagt tagctgaatt
    18601 agtgaagaaa cagcaaagta cgatggaaag tgaagcaaaa gcttatgttc aagacggtat
    18661 ggtaaaagca atgactgaaa atccaaaaat gagcaaagca gagcaagaac aacgtacgaa
    18721 agccttagct gctgaattcc aacaacaagc attcgcaaaa ttagtgaaag aagcaaaagg
    18781 cgaataatat tttgaacacc atgtaggagg ttgtgaaaaa gctgctctgc atcaagcagt
    18841 aagaacaatc agataaaaat agcactccat atttttcatc tgattgggct tagtgccgta
    18901 gatgcaagct tttgaacacc gtttaaggaa gaggttgtga gcctgccgtt taactctgag
    18961 tcacaaggag caatttcaaa aaacagcttc tcatgtttgt tgactattgt gacttgtgac
    19021 cgaggagttg gcaggagaac accgtttatt cgaaaaaagg aactgcgaca agacttttgt
    19081 cacagttcct tctttttttt gctatgctat actagatgta aaaaatagga gaaataaaat
    19141 gagggaaatt tattcttttg aatcaaaaat ctatgcttcc gaagtcggca agggcggggc
    19201 atatattatt tttccgtatg atataagaaa agaattcggt gctggaagag ttaaagtcca
    19261 agcaactttt gacaatgtgc cgtatgaagg cagtatcgtg aatatgggcg tgaaaaatcc
    19321 agatggttca gtctgctaca tccttggact acgaaaagat attcgtaaaa acatcggaaa
    19381 agaaatcggt gatattgtag cagttacagt gaagcaaaaa taaaagaggt tgtgacaaaa
    19441 gacgtgtcac aacctcttga taaacggtgt tcaaaagcca gtttctcggt agtaagtcaa
    19501 atttatgcaa aaatgtggaa acccatgttt acaaaatttt tcttactact cgaaacgaag
    19561 cggctttatc acaacctctt gataaacggc gttcaatcag ctgtccctcg gtattagctc
    19621 aaaaacggca aaatatgaga agctattttt ccattttttt ctctcatact caggtcataa
    19681 cgctgatttc acaacctctt ctttcataat ggtttttcac catctttata ataaactggt
    19741 tctttgatat ggaaatctat tttttccaac caatctaaaa tcttgtaacc taactcttct
    19801 gacatcggaa aagaggcgtt gatttgtgca ttggagatat ggtcaacatg gataccggaa
    19861 gtgatcgtac aacttcccgg aacggcagtt ttgatgatca cagctatttt ttcggctaag
    19921 acatcgtctt tatggaaccg accatcgtgg ctagggaaac gtacagtttg catctctgta
    19981 tcacgagaaa atgtagtgac tgttccgata tgtggtgtat ctccgcctgt taaagtgatc
    20041 aataagtctt taccgattac tttaacagca gcttggatcg tgaaacctag tttggttact
    20101 tcaactatcg tttctttttc catattaatc accctgccaa cgttttgaat gctcatttac
    20161 aatttcaaat tgatccaaaa gtttcattgt atggtgatta acaagatctt ggatcgtttg
    20221 aggctgatta taaaaagcag gaattggtgg tatgatttgc acacctagtc gtgctaattt
    20281 agtcaagttt tccaagtgaa tggcatttaa tggcgtttca cgaggaacaa tgactaactt
    20341 tcgttgctcc ttcattgtta catcagcagc acgtgcaatc aggttgtcgc ctaaaccaac
    20401 agagatacct gcgactgttt tcatacttgc cggtacgatg atcattccat cggtcaaaaa
    20461 tgatccgctg gcgacagcag cacctaaatc tttgtttgaa taatggtaat caaacaggct
    20521 ttcgaattca gttagtgata agtcggattc cagctttaag ttctgttttg cccatggact
    20581 gatgattccg tgtgtttcta tcatcggata ttcttttagt ttcttcacta ggttgatggc
    20641 ataaatggtg cctgaagcgc cacttacacc aatcacgatt tttttcttcc gttgtgccaa
    20701 ttgttccatt ttccgcactc ctttttatga tgtcaaaaca gttgcagatc attcattatt
    20761 tcaaatattt ttcccaatct tctacttctt ggaattttgc acgtacaaaa tgttctttca
    20821 tatcgaaagg aactgtaccg tcaaagatag tttttgcact tatcccacgg aaacgaatag
    20881 agccaggatt atattctggt aattctgatg ggtccaatgg atggttcctc attcctggga
    20941 tcacgatgat atctttatct ccttggaaac gagtgttgaa agtccaaact acatcgttca
    21001 tgtcgaaaat atcaacatct tcatcgacta aaatgactgt cttcaattct ttgaaggctg
    21061 ataaagcaag aatagctgct tgacgctgaa taccttcatc cgcttcgttt tctttacgga
    21121 tttgcatgat ggtcatcaat ttaccaccac ctgcaggagg attgtagaca tttactactt
    21181 ttcctggaat agctttatcg accaaggcaa gaatacttgc ttctgtagga ataccggcca
    21241 tagatacgtg ttcttcactg ggaccaatcg ttgtttgcat gattggattg tcttttcggt
    21301 gagtaactgc tttgactttc actacttgta cagctggatt agcatcccca gtatagccag
    21361 gaaattctgg cattgctttt cctgagttcg tgttgatatc ttcttgcatt gtttcatttg
    21421 gcatgatttc tgcttcaatg atgaattcag cacgagcaat acccacttca tcgactgcta
    21481 taccatcaac gatttgaata ggttcgttac gcaaagctcc tgcacaccat agttcattgt
    21541 agccaagtgg agtggtaggt ggttcgaaag tcgtgccaat ggcaattgct ggatctaaac
    21601 caatattgat agtgataggc attggtttat tcaaggcttc gaattgtttt tggaagtgac
    21661 caatgtggcg tccgccaggc atgatgtaca taccgatcgt atctttatct tctagaacca
    21721 tacgatggat cgttacatcg ctcattgttt tttctggatc tgatcctaag actacaccca
    21781 ttgtgatgta tggaccagca tcttcaggag tatttgtagg tgcaggcaaa atgttgcgaa
    21841 tatcgaagtc tgcatcggta gctagatgaa cgacttcttg tgctggagcg tctgctttgt
    21901 ctactttcac aggtttgatt ggattttcta cagcgtcttt caagaaacga ccaagtgttc
    21961 gataatcatg gtgcaaaatt tcacctacac gtttacgact agccattgtt ccgatgttca
    22021 cacgtgtgcc ggggaaacct ttgatattgt tgaaagtcat agctggtcct tcttgagtcg
    22081 gacgttttac tgtaccgcca gcaccgatat aacggtaaac accagataat tctgcttcag
    22141 gatcgatttc aatatctgtt tcgtgatatt gacctggaag tgtttttagt tcttcgatga
    22201 cttttcttaa atcatacggt tgatctgtca tgagagattc ctccttagtt gtctttacct
    22261 atctatagta aaaggtgaaa aagaggaaaa caattcaact tgttcggtaa agtattctac
    22321 aatggaatgg atgcgttttt ttgataatag aataaactat gatatactta tcactaaaag
    22381 aaagcgcata cttagtgttg gaggaaggaa agtgaaaaaa atggaggagt catttcctaa
    22441 agcagtaaaa gtggaaaata tagcgaatat tttgaaagtt acatttgaaa acggagaagt
    22501 aaaatacgtg aaatctcatt ggacagaaga gataaccgat gccttgcaat ttggaaaaaa
    22561 aggaagagga aaaagaaaaa atcttctcgc actttctcgt aatatgtgga ttgggactga
    22621 agtaacgatt gaagcagatg gaacagtatt cataaatgga aaagacaggt atacgccaga
    22681 agagttgtgg tacaaaggaa agaaaagtat accagaatta taaaaaataa ttaaaaaaaa
    22741 cagcgcgaaa caaggaacat attacttcct cgtttcttgc tgttttctac tatttcagcg
    22801 ctcttatgac tcaaatctaa atgtggttgt cacaacctta ttctgcacgc aaagcgatag
    22861 cggcgtcttt tttcgctgcc attcgtgcag gaagatgacc gccaagcatc gtcaatatag
    22921 tagagacgat cactagaata atcgcatgga caggatttag ttgagcaaca ttttttagat
    22981 ccgtcatgtt gtataagatg ctattgatag ggaacgtagc tagccatgca ataaacacac
    23041 ctaatatccc agaagaaata cctaaaatac acgtttctgc gtcaaatacg cgagtgatgt
    23101 cttttttacg tgcacctaaa gcttttagta caccgatttc ttttgtccgt tcaatcacag
    23161 atgtataagt aatgatactg atcatgatca tacttgttac taaagagatc cctgcaaaag
    23221 caataaggac ataagtgata gcatccatca atccgccagt cagttcagtc atcgttccag
    23281 ctaaatcagt ataaatgatt ttatcttcat ctgatttgcc tttattgtaa tcatctagat
    23341 aatccaagat cttttctttg tcttcaaaat tgttcggata aatcatgata cttgaaggca
    23401 agctgtctcc acctaaataa ctaagcaatg tttgtttggc attttcgtca actttttcag
    23461 tagttaagac atttacacca ctgtctcttt gagctttgac gatttctgat tctttgtttt
    23521 cgttgacgat ttgagtcgtt aattgatcgc tataagcgat tcctggagat aagagattca
    23581 ttgtagaaga agatttcacg cgtaggatcc ccgagatctt caattcatca gaagcattct
    23641 gatacatcgc atcataatct gtattaggga taaaattccc agttggaagt tttgtatagt
    23701 aagtattgtt gtttactaat ttgaatgttg taccaacgat atcatcaaaa tcaagttttt
    23761 cgtcttcttt cacatcaaat ccaagattct tcaatgcgtt gatattagta ttattattgc
    23821 cgtctacgat cagcacgaca tctgttgctg aggctggata acttccggca agtaaagaat
    23881 aattgtcttt taaaaagttt tctttgctag tgtcaagctg tgtagggaaa cttgacactc
    23941 ccacacctgt cattgctgac atcgtactag ataaagaaag agattccgta tcaggatttt
    24001 gattcgagaa gctgacaggc tgtactttgc catttacatc acgtaaaaga ttgattcctg
    24061 tagtacgggt aaatccgata ttattactta agttaggatc gatgtctgtt acgtaatcga
    24121 cgtatgtttg atcaatctta ttcgtgtgct gtgctttatc ttcttcgctg acttttgcag
    24181 taatcgtttt gctgtctgga taatccgctt tgcttgcacc caatccggca tcgtcacgag
    24241 tctggttagt cgttacctta gaaatagtaa tcggaaattt cgccatcgtt tcagcttgcg
    24301 tgttatcgat ttgtttttgg aatccagaag aaagggacag aacgatcgcg attccgatga
    24361 tcccaatact ggaagcaaag gaggtcaaga aagtacgtcc tttttttgtt cggatattgt
    24421 tgaaggaaag ctttaacgct gtccaaaaac tcatctttgt tctgcgtaag ttaaattgat
    24481 catcttttgg tcgttcgatg tgaggatggg aatctgttaa gatcttacca tcagaaaatt
    24541 caatgattcg atctgcgtat tgatgggcca gttcaggatt atgtgtgacc atgatcacta
    24601 atttttcttt cgataactct tggatcaatt ccatgatctg gatacttgtt tctgtatcta
    24661 acgctccggt tggttcatcg cacaaaagga tatctgggtc attggctagt gctcgagcga
    24721 tggccactcg ctgcatttgt ccaccagata actgatttgg ctttttatgc atatgatttg
    24781 tcaagccgac tcggtgcaat gcatcttctg cccgttttcg tttttcgtct ttagaaacac
    24841 cacttaatgt catcccaagt tcaacgtttt caataatgcc tagatgacca atcaagttgt
    24901 aactttgaaa aatgaaaccg atagagttgt ttcggtaggc atcccagtca ctgtccttaa
    24961 agtctttagt agactttccg ttgattacca tatcaccgga atcataatta tctagtccac
    25021 caatcacatt cagcatagtc gttttaccag aaccactagg acctaaaatc gctacgaatt
    25081 ctttttgtct gaaagcgaca gacacaccat ccaatgcttt ggtggtggtt tcgccgactt
    25141 tataatattt ttttatatct tttaattgaa gcataatcac ccttctcccg tattgaaata
    25201 ttcggtatac taataagtat atcagaacaa tgatcgtagt atacgaaata aatgttaact
    25261 gaagatgaac tacaagaaaa aatctagaaa tttttcaaaa aacagaggga gatcaatgaa
    25321 tcgtatttta gtagtagaag atgatccgca attacagttg ctttaccgtt ctgtgttgga
    25381 acgagcgggc ttttcagtca tcaccgcatt gaatggagag gatgcgctga aaaaactaga
    25441 agcgacacgt atagaattaa tcattacaga tatcatgatg ccgaaaatgg atggctatga
    25501 cttgctagac tcattacgta gcaccagatt tgacacacct gttctaatga ttacggcaaa
    25561 ggccgatttt gaggataaga aacgcgggtt caaattagga gcagatgatt atatgacaaa
    25621 acccatcgat gtcaatgaga tgatcctacg tgtggaagca ttgcttcgac gttcaaagat
    25681 caattacagc agtagcttga taatcggaca aacaaaatta gagctagatg cttatacagt
    25741 gttacaagat cagcattcgt tgattctgcc tcaaaaagaa tttctgcttc tgtataaatt
    25801 actgtcttat cccaacaaga tcttcactcg ccaacagttg atggatgata tttggggatt
    25861 agatacgaat acagaagaac gaacgatcga tgtacatatc aaacgtttaa ggacccgttt
    25921 tgaaaagacg gaagattttc aaatcatcac agtacgggga ctaggctata aggcggttat
    25981 ttaaagatga aaaaaaagct attttcacaa ttatggatct attttgctag tattgtcttc
    26041 atttcgatct tagtgacact gctgtgtttt ctcggtttta ttttcttatt gtctcgacat
    26101 tctatctcgc ctgctgaatc ggctggaaaa ccaacgttat acccgttatt cgtctttgcg
    26161 gggttcagta tggtcgtggg tacaggaata tcgatttttg ttgggcggcg tatcctgcat
    26221 ccaatcagtg cgctagggac aaatatgagt ctggtagcaa cgggagattt ttcgattcga
    26281 atggatgaac agcagaaagt agcagaagta cagcaactgt ataaagattt caacgttatg
    26341 gtccaagaac tcaatagtat cgagacactg aggaatgact ttgtgtccag tgtatcccat
    26401 gaattcaaaa caccactagc aacaatccaa ggatatgttc aattgttaca agccccaaat
    26461 ctctctgacg aagaacgcca aatattttta tatcggatta tcgaaagtat cacgcagctt
    26521 tcacaattaa cagagaacat cttaaaattg aacaaactgg aaaaccagcg tatccaactg
    26581 gaaaagaaag agtatcgatt agatgaacaa atcagagaag taatcgtttt ttttcagcct
    26641 aaatgggaga aagaacagct agaattggat atcgaacttg ctgcagtaaa ttacacaggc
    26701 aatgaagagt ttttgtacca agtgtggctg aatatcatgg ataacgccat aaagtacaat
    26761 caaatcaatg gacagattca tatcaaacta tttgagacag ccacagagat tgtactggaa
    26821 gtgaccgatt caggtgtagg aatgaatgaa gagaccagag atcgaatgtt tgaaaaattt
    26881 tatcaaggag atacaagtcg tcaaatttct gggaatgggc taggactttc actggttaaa
    26941 aaaattctag aactgcatga tggacgtatt gattatagca gtatcgaagg agtaggaacg
    27001 acagcaatga tacggttaag taaacaatag gaaaaagaat aaaaccccta aaaattctat
    27061 tgaaggtttt taggggtttt tagtcgtttt tttgtgatta gggaaatgtt cttacggttc
    27121 ttttggcata aaaatcgctg ctttcttatt gaactacgag aaatgttaga ggtgtcattg
    27181 aaacaaggac atgatgcaag aaagagagcg aaagtcatgc gtcgctctct ttttttgggt
    27241 ggatagatgg acagaaaatg tagggcttag ttttcttctt gatttaaata ctcccaaaat
    27301 gtatctgaag ccaaagaatg ctcaccgact ttacgagtaa atgcaagata actctctgtt
    27361 gttggagaaa tagggagaat cacagtattt tcttttaata gattcttgac tgttttttcc
    27421 ataacaatag caatccccat gtcatttgca atcatattga tgatcaagtc gattcttgct
    27481 cctttataag agatttttgg ttcaaatcca gcttcgcgac acagatctag tacaggttga
    27541 tacaagttcg tagtggggcc aaggagcaaa aagttctcct ttttcagttc gcttagatcc
    27601 aatttctttt tactagctaa aggatgattt ttaggtagaa ctgctacaaa atcgtctgtt
    27661 tcagtaggca accactcaat cgaacttggt ggggcctgga aacttctagc aaagtggatc
    27721 gtgtcactat gttcattggc gtcattgtaa gttaattcga cactttccac ttctttcaac
    27781 tggactgtaa attcaggatg gcgtttcaaa aactcggtga ttttggaaaa acctttataa
    27841 ttgatcattg tcggtatcgt taagatattt aatgaaagat tgttgtcttt cgtataggtt
    27901 tcaagcactt cttgcatagc atggtattgt tctacgacat tttttacata tgggagcaat
    27961 aagcttccag cttcggtcaa ttcgattttt ctaagggcgc gttcgaataa tttgacgtct
    28021 aattctgttt ctaacgaaag aatctgttta gaaatatttc cttgggtggt gaattgtcga
    28081 tcagcagttt tggtgaaatt cattgtttcg gctaaatcaa gaaaaacttc gaatttatgg
    28141 atatccatca tattcctcct acttattcca ataaagaata ctttaacaca aaaaatgaat
    28201 tggtgtaatc ttctctgtct gttacaatct ttcttgcagc gaaagcaata attacagaaa
    28261 tttttctgat ttttttcgct tcgtagaaaa agagaggagt tttttgatgc caactggagt
    28321 tttgatcaat gtaggttccg ttttgtttgg cggactaatt ggcggattag taggaaataa
    28381 attaagtgaa cattttaaag cacagctgac gatggttttt ggtgtgtgtt cgatggggat
    28441 gggaatctat tccattgcgc cgatgaaaaa tatgccggct gttatttttg ctttagtgat
    28501 aggaacagcg attggtttga ttgttcattt aggtaatggg ataaataagg gggctgcgct
    28561 gatgcaagta cctatttcta aaatcttccc tagtgaaaag cttggtatga cccacgatga
    28621 atttatcagc acattagtga cggtcattgt tctattttgt gcaagtggta cggggatcta
    28681 tggaagttta gattctggga tgacaggaga cagtacgatt ttgatttcta aatctgtcct
    28741 tgattttttc acagcagcta tttttgcgtg taatttaggg tatgtcgttt ctgtgatagc
    28801 aattccccaa ttcattattt tttatatttt gttcttattg gcaaaattta tttatccatt
    28861 gactacacca gacatgatct tagattttaa atcttgcggc ggattcttga tggtcgctac
    28921 cggttttaga atgatcaacg tgaaaatgtt cccagtagct gacatgatac ctgcaatgat
    28981 cgttatcatg ccactgagct ggatgtggac aaattggatt atgccactgt tataataaaa
    29041 atcaaagaga agccattttt tgctgactaa aaaggatcaa atcttttagt cagttttttt
    29101 gtatttgaca aactgatttt gaaactatat tatatgttgt ataatataga ttgaaataaa
    29161 atattacact tgagaataga aggtgacgta atgcacatcc agattccaac tgttcttctt
    29221 gatggtactg tgctagcagc attaagcaag gaagatatgt atgggtatgc cttaacaaaa
    29281 atcgtacaag aaagtctctc tgtcagtgaa tctacactat atccggtttt gagaagattg
    29341 aaaaaagaag gatatcttga gacctatgat gaaccttttg aaggcagaaa ccgtcgatat
    29401 tactcgttga caccaatggg aagtcgtcat ttagaagaaa ttattgatga atggattgtt
    29461 tttcgagatt ctttagaccg gttattggag gagagcacaa atgaatgaat atttgaatga
    29521 agttgtggat catcttcaag aaattcctga agacgatcgt tttgatttga tccagtatta
    29581 tgaggaatat tttttagatt ctggaaaaac attagatcag atcattgatg aatatggtac
    29641 accaaagcag tttgccttaa aattaaaaat cagttacttt tcagaagaag aacaagcaga
    29701 aaacgagtta gtgaaaaatc caaaaagaca aattcgcctg atttggttaa tcattatcgg
    29761 tttatttgct tctcctgtcc tcattccact agcactgggg tttatattgg ttattggggg
    29821 actattggtt gctttactag cgctcatttt tagtatctat gttttatgta tcagtatctt
    29881 aggtgttggc ctattcatga tcatctcagg aatcagtgtg tttggacaat cgattctgag
    29941 tggattattc tttatcggtg tcggtctgtt cgccacagga agcgcagtat ttatttcgcc
    30001 actgttgctg aaaggaacaa aagggctttt ttatgtcatg atgaactttg ttaaatggat
    30061 gggacgacgt tttattacaa aaagagatct gcattcagcg ggcgtttgaa ggaggacaca
    30121 taaattgaga ttgaaacatt ttttgattac cggtattggt ctgatgctta ctggtggcct
    30181 cctagcaggt gcaacttata cattaggcgc tcaaaagagt ctgacttggg ataatggtcc
    30241 tcggttgatc gatatggtta ctgagacaaa aaaaatcaag gatgcaaaca aaatcgtcat
    30301 ccatgcagaa aatcaaacag tttcggtcat acgcggattg gattttgaga taaaaacgac
    30361 ttatgataag acagaaaagc cagaaataaa ggagaaaaat ggcgtgttga ctgtgaatgc
    30421 agtcaaaaaa tcaacaggtg caatcattag tttagaagac acaagtgcac aaatcactat
    30481 tgttgtccct gcagatcatg aattatctga attgacaatc gaagggaata atagtgcaat
    30541 tgatatcaac gaagtatcaa tcaaaaaagt gaatactaag acacatgatg gctgggtatc
    30601 gttcaatgaa tttacaggag gaacaataac tgcgaaagat gaattaggct cacttcgatt
    30661 agatgaggcc aatgtggata acttgatcgt cacaggtgaa aacagcaact tccatctaga
    30721 agacagtttg atcagcaaag aaggaaaagt catcctaaac ggtggcaatt tatctttgca
    30781 tgagatggaa aacagtggct atactatcca aacgtctggt gaatcttata ttgaaaaaga
    30841 ctaccagcca ataacaaata ctttgttaga acaaggacag aaaaagctaa agatcactgc
    30901 taaagacaca tcgatcaata ttacgacgga tcaagaggac aatgaaacag attgatcctg
    30961 tactcaactg gatattttaa gaaaaaacag caaagatcct tccaatcttt gctgtttttc
    31021 atcgcttaac gcacataact atagtaaaat aagaaagaaa atatctaaaa agaaaacagg
    31081 gtgaaagagt atatgaaggt agaagaaggt caaagagaaa agttaaaaac agaaatggaa
    31141 agattacata cttatatcac tcaactaagc caaaccttct atgatccaga caaagaaaaa
    31201 gtgatggtta attacccgaa caattcagaa ggtcgccaat tagagcaagt gtaccatgaa
    31261 gttttcaaac atttattgac ggtgaagaaa gagctggatt attattcttt accgattatc
    31321 gatacaggaa tattgaagta tgatgggaag aaggaacgat ttatctttaa atctgttcgg
    31381 gaagatttgc ctctttcagc agggatggat ctagaggtct tggtagaaga ctattttaca
    31441 gaagaaaagc actgggttcg aacaaaattg gattatttac cgcaggcagc cggagggaca
    31501 caggcaagcg gttggtacat cactgaagac aaagagttag aactagaagg tgtaatggcg
    31561 cgtattcgaa aaaaaaatta aaaaagtaac attagatatt tattgaagga taaaggagcg
    31621 caggaagtag catgagagaa aaaagagcat tttatatcaa tggttatgca gggattgtcg
    31681 gattggtcgt attagcttta gttggattgt ttttcttcta tttaggtatg tggcaagcga
    31741 aagtttgggc acttttttta agtatttttc tttggttgat cacgttattg ttgttaagtt
    31801 cggcaactgt agtcagtcct aatcaagcaa aagtaatttt gttttttgga caatatttag
    31861 gtacgattcg agaaaatggc tttttcctta cgataccttt ggcacaaaaa atgactgttt
    31921 cgttgaaagt tcggaatttc aatagttctg ttttaaaagt caatgatttg gatggaaacc
    31981 ccatcgaaat ctcagcagta gtagtcttta aagtcgttga tacagcaaag gcattattcg
    32041 atgtagcgta ttatcaagat tttgtagaaa tccaaagtga gacagccatt cggcatatcg
    32101 ctagccaata cccgtatgat acattcaatg agaatgattt gacgcttcga ggaaacacga
    32161 cggcagtgtc tgacgagttg caaaaagagc tgcaagagcg tttagcagta gcaggtgtcg
    32221 aagtaatcga aacacgcttg aaccatttag cctatgcaac agaaatcgct agtgccatgc
    32281 tccaacgtca acaagcaaaa gccattttgt ctgctcgaca aaccattgtt gaaggagctg
    32341 tcacaatcac tcaaatggcc ttagagcaaa tcgaagatgg acaagaaatc aatttcaccg
    32401 atgatcggaa agtccaattg atcaataatt tacttgtctc aatcattaca gacaaaggaa
    32461 cgcaacctgt tatcaataca ggcgacatga aagaccgtaa gtgacatact ttttgtaaga
    32521 taggaagaag gagtttagga cggattattg tcttgaactc tttttttagt tgttttaaag
    32581 aaaatgacaa aattgaaaga agaatgatag ttgattcgaa ggcagaattg ttcgcttttt
    32641 tctataatca gtatataaag taagagagaa ggggaaaaag tgaaaaaact tctgatcggt
    32701 ctacttgttt tcatcgttgt ggtacttgca ggggtgaaaa tcgcagatta cgtagttatg
    32761 ggtggagaag aatactatat acaaattacg acagatggta caaaaacagt ttcaaaatca
    32821 gactctggac aagaaacagt caactataga tatatcctgc ctggctatac gaaagagggt
    32881 aaggaaaaag aactggactt caagggacaa ttgactcgac cgcttcgtaa aggagcatat
    32941 ttaaaaatca cctggaacaa aaataaaggt gtcacttcgt atgaagaagt cgaaaaaaaa
    33001 gacgtgccga aaacagcact ggaaaaacta attaaagggt agggaaagaa atgaacaaaa
    33061 tagtcgaagt acagaatgta acaaaagtat acggaaaaaa caatgagaaa aagacgcaag
    33121 cattaagcgg catcagcttc gatgtagaaa aaggcgaatt tattgggatc atgggcgctt
    33181 ctggttctgg taagtcgaca cttttgaata ttttatccac attagataaa ccaacagatg
    33241 ggcatatccg aatcaatcaa aaagatgtga ccacattaaa aggaaatcaa ctagcagatt
    33301 ttcgtgcgaa tgagattggc tttattttcc aagatttcaa tttattagaa agcttgacag
    33361 cacaagaaaa tatcgctgtt cctctttctt tacaaggcgt cagaccaaaa gaaatcaagc
    33421 aacgtgtcca aaaaattgca gaacgtttat ccatctctca tattttggaa agctatcctt
    33481 ctgagatttc cggtggacaa aaacaacggg tcgccgccgc acgtgcattg atcacacaac
    33541 caacgattct attaggggat gagcctacag gtgcgctgga ttccaaaagt gcccgggatc
    33601 ttttagatac gatggacgaa ttgaatacaa aagatcatgt atcgattctt cttgtgacgc
    33661 atgatccgtt ttctgcaagt tattgccaac gtattttatt catcaaggat ggcggtatcc
    33721 atcaagaagt gaaacgtgga gatcaaagcc gtgattcctt ctatcgagaa atactatcta
    33781 ttcttggaaa cttggaacag tagggggaga ttgactatgc tttggaaatt atcacttact
    33841 gggatcaaga gccgtttaag agactacttg gtgttattct caggattagt tatggcatct
    33901 gctatttttt acatgtttga atcaatggca agcaacgaag cttttttgaa aagtaatacg
    33961 atcgttgcgg ctacagttat cattttccga ttcggttctg ttttactagg gatcatcaca
    34021 ttcgtttata ttttatatgc aaattccttt ttgatgacga tgcggcaaaa agactatgca
    34081 atgtttatga tgctgggagc aaaaggcaga aaaatcgcac agatgatttt ttctgaaaca
    34141 ttcttagtag ggatcgcagc tactttagtg ggttcagctg tcggtgtagg attgacaagt
    34201 atcgtccacc gattattagt ggatcagtta gatctcaata tttcgcattt tacacctttt
    34261 agtattcacg ggttgttgat cactgttttg ttttttgctg ttttgttttt attagctgct
    34321 gttgtcaatg ctttttcgat tgtcaaaaaa ccgattttag cattgattcg tgcggatcag
    34381 acaccaacaa gaatcaagca gcataaattc ttgtttttcc ttgaagtagt actgggaatt
    34441 gcttttctag gctgcggtta ctatatgatg aaacacgtgg ggacctatca agtctttggt
    34501 ataggggtag ccttagttac gatcgtatta ggaacttatt tcattttcca ttctgtgatc
    34561 attttctttt tatcattact aaagaaatca gaacagattt cattgaaaaa attgaacaat
    34621 ttcacattgt cacagttaaa ctttcgtatt cgtgaatata cacaaatgct ctcaatggtc
    34681 gctatgctgt ttgccttggc actgggcgct ttgacggtag gattaggttt taaaaatgaa
    34741 attgcagact tgacagaaaa caattctgga tatgatctag tgatgaataa tcctcgggca
    34801 gaagatcagc aaaaaatcaa agaactttca ccaacacttt ctgcttctta tactcaaaaa
    34861 gaagatgcgg gaacgattta ctataatgca agtgaatttg cggctcaacc attgatcatg
    34921 ataaaacatg aagatggaac accgccgaag atcacgaaag aaaaagttcc tgctaaaaaa
    34981 atgaatgaac tgactgtaca agaggaactt cgaagctatg aattgccgga acagcaagaa
    35041 aaagaaatca aggtagtcag tcaatcagaa tttgatcaac tgaacttgcc acaatccact
    35101 ttacagctag ttcaggtaaa agacttccaa gcaaacctga aaccaatcga aacacttgtt
    35161 gctcaaaata aaatgaacaa tccatctttg caaaaagtag agtacagcaa ccagaaatat
    35221 gaaatgtatg aagtgtataa tggtctattc tctggttttg aatttatggg attcttccta
    35281 ggtttagctt tcttgaccat gcttgctagc tgtttgatgt tcaagatctt gtcaggaagc
    35341 aagagtgaca ttgctcgtta tgaaatgctt gaaaagatag gaacacgacg cgggttgctt
    35401 aaacaatcga tccgtagaga agtaggcgtg ttattcttag caccaggaat cttaggtgta
    35461 gtccatgtct tattcggatt acaaatgttt ggtctattca tgcaaaatcc atacaaagat
    35521 atttgggttc cgtttacgat attcttcgta ttgtatttca tctactatgt actgacgaca
    35581 tggttatata ctggaatcgt attgaaaaag agattgtgaa aaagctgtcc tgcatcaagt
    35641 aataagaaca gccaagcaaa aatagctcct catatttttc gtttggttgg gcttattacc
    35701 gcagatgcaa gcttttgaac accgtttgtt cggaaaaaga ggttgtgaca atatttttgt
    35761 cacaaccttt ttttcacggt cttttattag aatatagtaa attttttctc gttactcacg
    35821 gaataagctg ttaagaaaac ggtttccatg tatactggaa tcagtgcaaa tgaaagaaaa
    35881 gagggtgcaa ggaacatgga aatcaatgaa caaaattttg gcgaaaacta tcacttgatt
    35941 acgatcacga atcaaaatgg gacatctttg tctgtcagtg atcttggggc acgggttgtt
    36001 cattttcaaa caataatcga taatgaaaaa cgagagttga tcttaggttt tgatgaagca
    36061 aaagaatatc tagaaaaaga cccttatatc ggtgcttcaa tcggacgtat ggctggacgg
    36121 attacgaatg gcacattcaa attagatgat gaaacgttcg aagtaaaaac agacccggac
    36181 actggtcatt gtttacatgg tggtgcacct agctttgaag ccaagcagtg gcattataca
    36241 gtcatcaatg gtgaaaacga agcatcggtc attttctatc agactagccc agatatggaa
    36301 aacggatttc ctggaacttt agatgtagaa gtacggtata cgctgacgaa cgatgataca
    36361 tggcgagtga cggtccaagg gatcagtgac cgcaaaacag tattcaatcc tacaaatcat
    36421 gtctatttca atttaaccgg tgatccagca cagtcaatcg acgaacatat actttggttg
    36481 aatagccgat tatttgctac gctcaataaa gatacaacgc ctacaggaga agtagtttca
    36541 gtaagtggca cagcatttga cttccaacgt cctaaaaaat taggtgaggt ctttgccagt
    36601 gattttcgcc aatcaatgat agtgggcggc atcgatcatc catttttgtt gaaaaaacaa
    36661 tctggtttac taaatgctgc ggaattgaca agcccagatg aaaaagtatc gatccaagta
    36721 aaaacagatg cttcaggaat cgtgattttt acagcaaatt ttggagaaga tggaccggaa
    36781 atgcgcggga ataaattagt aaatcatggc ggtatcacat ttgagactca agaactgcca
    36841 ggagcggagc gacttgaaag ttttggagat gtcactctgg aacctaacca agtacgcgag
    36901 tttgtaacgg aatacaaaat aaatataaag aaatagaata aattaaaaag ggagtgtgac
    36961 actgtcacat ccccttttta atttattcta tttctttaaa ggcagatcaa gccagaatga
    37021 tttgtctaaa cttaacaagg ttagtacagg aacagttgca gctttaactg tacgagtagt
    37081 tgtttctggt atctgtcttg ccgtaaaatt gttccacaaa tcccagattg aagcgacacg
    37141 gaagatggaa gaagcgttgt tgacgcgttt tatcgttgaa aattctaatc ctgtgattgg
    37201 cacgccatct gttgtccatt tgattggcac atcgaatcgc ttagacatat tgaggatttc
    37261 agcgtttgct tcttcagttg ttgctgcttc ttttttcggt tcatcatatt ttgtcaggtc
    37321 gtacgcttcg atgatcgcgt tcaatttttg tgaatattgg cgatctgtag cataacgtcc
    37381 ttccaaatat ttggttgctt ctttgtagtc ttttgtttcc gacttccaag ttggtttgta
    37441 gaaatcagga ttgccagtca gtccattttt gatcaagtcg gcatagtctt ccaaactttc
    37501 cttgtaagaa ggatatttac ggaattgtgc gcggatttgg tagctttgtc cggaactatc
    37561 ttgttcaagt gtattgaagg tcacgctgct tcctttatat gatcctttga taccaaaaag
    37621 gttatgattt ggttcgcttg ataataagct gtttccagat ccactttcaa ggatagcttg
    37681 agccatcatg actgatgcgt agattccttc tttttgcccg atttcctgtg catcatctgc
    37741 aatctttttc aagaactgat cagttgtttg gttttgactg aaatggaacg agccatctaa
    37801 tccatctaaa atagatgagc cgcctgtcag cgaacctgaa gcagcaggta aacctgctaa
    37861 gtttactcgg acagcaaaat caggcgtgaa atctgaaata gaagttactc gaactttatc
    37921 tcctggttga ggcgcatgga taaattgtcc gttcccaata tagataccta catggtgagt
    37981 aacaccggaa gaaggtcccc agaagacgag gtcgccaggt tgggcctgac ttactggaat
    38041 ctgcgtacct gcatattgct gttcgcctgt ccagccaccg atataatgac cggttgcttt
    38101 catatatacg taataagtca aaccagaaca gtcaaaagta tttggacctt ttgctcccca
    38161 tacatatggt tttccaagat gcttgaatgc ttctcgaacg attgcttgtt ggacattcgt
    38221 tgtatttgta ggcaatacag catcaattgg tgattttaca acaaaatcag aagaagcaga
    38281 agatggattc tctataccgc tttgatttgc tgtatttgga cgagatgaag cattgttcgt
    38341 tccgccattc gatgaaccat tgtttggatg gtttggttct ctctgagtat ttccattgtt
    38401 attcgatcca gatgggtttg tttgattcga agaattcccg ctgttcgaat tattgttatt
    38461 attgtttgaa ttatttgaac cattattatt gttgttatta cccacatctg gtttgtttgg
    38521 cgtttccgga tctggtgtac tagggacttc ttcactagga tcagttggtt tctctgttga
    38581 agtatccggt ccagctttaa attctgcagt aatagataaa ttgttcgtac ctactgtaaa
    38641 ggtctttgca tcataattta cttctttggc accattaaca gcgactgaag caatttgttc
    38701 accttcagct ggcgtaatag tgtaagttac cttcgtttcc gctaataaac cttctaccgt
    38761 tccactttcc gtaatatcca aaggttgctg ttcaggggaa tccgctgtcg aagcagtcag
    38821 ttggatctta ccaatcaaag aaggagcaat tgtaagggaa tatgtctcgg ctggcttttc
    38881 attttctgat ggatcagccg gatcaatttc agttggctcg gtcgatcctg ttgttgagtt
    38941 agttgttcca gttgggtctt ctgtaaaaga atccgttgtt tcactagtag ctgagctgga
    39001 tgtagtcgta tctgttgtga ctgtttgatc agctatttga ttatctacgg caaatacggt
    39061 attggtcgac aaaacagacg gagcaatcag ccaagtagca gctagcaaac gtatcgtttt
    39121 tttatttttc ataataaact agtccttttc ctttcattga ttttctgtct tattcagcat
    39181 tcattagaca ttttttggaa cagataatcg tgtcgaaaag ctttttcttt tcataaatct
    39241 gtctgtgtat tctaaataaa acaatttgta aataagcaac gagcattcat tcgtttttct
    39301 ttgacgttca ttttattgca tagaccacct ttgtttgggg ataaacaagt ggggataaaa
    39361 atggttatgc atatgtaaat tataccaaag tttggaaagt atcacaaaaa tttataaaaa
    39421 taatgatcct aaaaagaaaa agactgaaat atgtgataaa catctcatac ttcagtcttt
    39481 ttcattaact attcataaga cattaggtct tcatcaaacc cgctaacgag agtagtgatc
    39541 attgctacga ctagactaac agccagtcct gctaagtacc agaaaaaagt accggaaatg
    39601 aatgcaggca atgtggtcag actaccaaat acaaaagcga tcgctttcac ttgggcaaat
    39661 cccattacag ctccaccagc agctgcacca atgcaagcag caacaaatgg ttttttcaat
    39721 gggatcgcaa ttccgtaaac agttggttcg gtcactcccg caagtaaaat cgaagcaaaa
    39781 gcagaaccgg agatcgaacg ggtttttgaa cgtttacttc gcagaaatac acctaaagct
    39841 gcaccagcca ttccaaaatt ggctgctcct gtcaacggaa cgattcggtc gaacccataa
    39901 gcagagatat tactgatcat gacagggttt acagcccatt ggataccaaa tattaccaaa
    39961 atattccaac caccagcgat gattgcgcca ctgatcggtc cgttaatatc catcatccaa
    40021 gtaattgcgg cagctaaacc ttcgccaagg taaacacccg caggcccgaa taccattaac
    40081 gtcaaaggaa ccgtgataac taatgaaagt aaaggtacaa atactaattg catattttcg
    40141 cgaatatatt ttttgaggaa tttttcaaca aaagaataaa agaaaatacc taaaatcgcc
    40201 ggcatgacag tagacgtata ctgcatcagt actacaggaa tccccagaaa atcagtagct
    40261 gctttgccac tgtctgaaag taaagaggtc agattcggtt caatcagtgc tgcagcaatg
    40321 acagccgcaa tatatccatt cactttaaac gttttggcag cagaaaaagc aagaaagatt
    40381 ggcagaaaat aaaagacggc attcgacgca gcagacaaaa tatgataagt tccgcttgtt
    40441 tcactaagcc agccaatcgt agtcgctaaa acaaccagac cttttaatat accagaaccg
    40501 gcaaacagcg gaatgatcgg cgtaaagatt tccgatatca aaccaaatag tttttcgatc
    40561 ggatttagct tttctttcgg agctgaatga tcgatttgac gcgtcaattc cttgtaagca
    40621 ggagccaatc cctgatccat gattatttct gcatatctat cgagtaaaat gaaatactta
    40681 atggaaggga tttgctgttt taatttttct gcattggcta ctggctgttt tttcaatttg
    40741 atacgaagcc gagtcgcaca tggaaggaca gaatcaatat tgtcttttcc tcccaactgt
    40801 tcaatcagca tatgaatctg ctcggacagt accatctgtt caggattcat tgtcgtttcc
    40861 attagaagac cactccactc actaatataa tattggcgta aggtgtcatt tcgcctgtac
    40921 gaataaatgc atgacagtta ttcaactctt ttttcatttc ttcatgtggg ataaagctaa
    40981 tcggtgtatc tggtaacaat aatttgattt tttccaatat ttccgggttc attgtcttta
    41041 tttcttccgc caattcaatc gattgtacct caagttcttc taaaacgttt tctaaaacag
    41101 ataaaaaact tggaagaccg tttgagacag ccaaatctat tttttcagta ccaaagggga
    41161 caggcatgcc tgcatccccg atacttaatt tatcaaagtg ccccatttgt gcgattactc
    41221 gtgaaatatc tgaattgatt acttttcctt ttttcatgtt tgtttcttcc tctcattgtt
    41281 aattttagac tgctgattgt tctaaagctt cgcggtaagg gatagaaggt tgcgcaccat
    41341 aagactgcac agcaacagaa gaggctagat ttccataaag gatcgcttct ttcaagttac
    41401 taaggtctgg ctgaagtgtg ctgcttaatg cgccaataaa tgtatcacct gcggctgttg
    41461 tgtcaacggc atccacttta aaagcaggga cgataccgtg ttctttttct gtatgataga
    41521 aagcgccggc actgcctagt gtaatgatta ctgttccaat acctaattca tggagttttt
    41581 cggctgctgc gaccaaactg ttatgatctg tcactctgat tcctgtaatg atttctgttt
    41641 ctgtttcatt tggtataatg atatctgtct tttcaagtag ttcagtagga atcgtttcac
    41701 gagctggtgc aggattcagg atcgttgttt ttcctgcgtc ttttgcaata gaaaaagcta
    41761 ggatcgtcgc atctaagcta ctttcaaact gagcaataat aaagtcactg tttgtaatca
    41821 gttgcttgtt ttttaggact tcttgttcat ggaaagcatt atttgcccct gcatggatca
    41881 agatactatt ttctcctgct gcgtctacca taatcattgc ttgtccggtt gtggcgcctt
    41941 ggatttcagc tatcccagat gtatcgatgt tttcttttgt cagtagatct aataactgtt
    42001 gtccttcgct gtcagcccca acgcctccaa taaaagatgt ccgtgcgcct gaacgtttgg
    42061 ctgccactgc ttggttggca cctttacctc cgccagcgtg aaaaatctca tgcgcatgca
    42121 tcgtttcgcc tggcttgggc atgttggtta aacgaagggt agtgtccata ttaatacttc
    42181 caattactgt aaccgtgttc attttacaaa cctccaacta tctcatttat tttgatggga
    42241 aaattatttt ttaaaacgtt ttagtaaaac gttttaatag ttcgataaaa atatagcaca
    42301 ccttgaaagc tatttcaagg gtgcagttga aaatcttttt tctaatcgta caggtaatct
    42361 tttttcttcc cattcttttt ctgggaattg gatccgatct aacaataact tggcagatgt
    42421 ttgtcccaat tcgaagattg gttgtgcgat cgttgtcagt ttcggcttga tatactcgca
    42481 catatctata ttattatagc caataatgct gtagtcttca gggatgcttt ttccagcttc
    42541 ctctaatccg cgatataatc caaaagctaa ttcatcattt aaagcaaaca caccagttgc
    42601 agcagaatca agaagttctg ctgtgatctg gtagccacct tgttttgaga actgtgtagg
    42661 taagaggatc agttggtcgt gagggatttg gtaaacatca agagcagatt taaacccctc
    42721 aatccgagcg tggacatttt ccggtggatt ttcaggatag acaagggcga tcgtttgatg
    42781 tcctagacta agcaagtgca tgcccgctag gtaaccaccg cgaaaatcgt ctgttcgtac
    42841 ggcatcacta aatccttcag attttttctg atccaaaaca atgaagggcc ggccttgttt
    42901 tttcaaattt tcgttgattg catctgtaga gacagcagaa gtcgcgataa tgaatccatc
    42961 cacacctcga cgtgtgagct cggctagata ttcgatttct ttttgatgat cagaatcagc
    43021 attacataat atcgtgacga aattctgctt atacaagata tcctcaattc ctcgcatcag
    43081 tgtactgaag aatggattcg tgatatcagg aacgagtaca ccaattgttt tcgtttcctt
    43141 ggtaatcatt tgtctagcaa aatagtcagg ctgatagcct aattcttctt tggcagctaa
    43201 aactttctga acagttttcg gactgaattt ctccgtattt ccatttaata tcaaggagac
    43261 agttgtgatt gaaacgccgg aaagtttagc gacttctttg attgtgatct tttttttcac
    43321 catgttcata ctcctatcta aatcctgtgg ttattttccc atgaaatcaa aaagaagtaa
    43381 atgaaaatca cgtgtgccag tacttatttg ctttgttgga tagcttcgat tatttgtttc
    43441 gttgagcgta ctcgtgcagt tttcggaaat atctttttta tgaacaattg atgggattct
    43501 ttgtcacgat cactgcaagc atcttcagca agcacgatat ggtacccgtg ttgaaaggca
    43561 tctaatgcag tagcatatac accgtttgtt gtcgctacac cgcttaaaat gatagtttcg
    43621 attccacgcc ggcgaagttg aagatcaaga gaagtaccaa aaaaggcact tggattgtag
    43681 tttgtgatag tcaacatatt gtttgtatct ttcaaggaat ccttcaacaa caagtcagtg
    43741 aattctgccg gagcagacaa agcagatatt cctccagcat ctgtctgatg acttagataa
    43801 gagaaagtag tgatgtctac attcactaaa actttcaagg cagcggtacg tttcaatgtt
    43861 tttgctaaca aatcattgtt tgtcagaata gattgtgcag tgtgtggaga gagtgtaccg
    43921 ttatttacga tccctttttg catgtcgatc gcgacaaaag cagtttttga taaatcaaaa
    43981 atcatatttt cctttaaatc attcatgatg ttccttcttt caaataacaa tgttttttat
    44041 gtaagtaaat cataaatcgt ttatttgtca actaaataaa ggattccttt ctttagtcta
    44101 gagaaattca gtggtaaaat aaataagtgt gagaaaacgc attcgatgca tagatatagc
    44161 gagaaatatc gtgaaaatgg aggaatcaga gtgaagtatg tcgaagtaaa aaatgaatac
    44221 aaacgataca aaatgggaga aacgaccatt acagcaaatg acgatatttc tttttcaatt
    44281 gaaaaaggcg aattagtgat tatacttggt ccaagtggag caggaaagtc aacgattctt
    44341 aatattttag gtgggatgga tacacctgat gaaggtcaga tcattattga tgacacagat
    44401 attgcgcaat tttcagataa acagcttact gcttaccgac gaacagatgt agggttcgtt
    44461 ttccaattct acaatctcgt tcctaatcta acagcaaaag aaaatgtgga attggcaacg
    44521 gaagtttctc ctgatgcgct tgatcctgta gaggtattga ggcaagtggg cctagctcat
    44581 cgattgaata actttccgtc ccaattatca ggaggcgaac agcagagggt ttcaattgct
    44641 cgtgcactag ctaaaaatcc caaacttctt ttatgtgatg aaccgacagg cgcgctggat
    44701 tttgaaacgg gcaagcaagt attgaaatta ttgcaaaacg ctagcagaca acacggcaat
    44761 accgttttga tcattacaca taattctgct ttagcgccca tcgctgatag agtcattcac
    44821 attaatgatg ctaaagtaag gtctgttgaa ttaaatgatc atccttcatc cattgatgag
    44881 attgtatggt agggggattt tatgaaaaca agaacatatc ttaaagcagg ttttcgcgaa
    44941 attcggcaat ctaaaggacg attcattgca atcatcctta ttgtcatgct aggaacactt
    45001 ttatttgtag gtgtcaaaac tgctggacct gtcatgcaaa aaacgatgga tcactatgtt
    45061 ggtacagcag gactttctga tttgcaaatc gtttctactg gtggcttgac acaaaaagat
    45121 attgctcaag cagaaaagat cccagatgca aaagtagaaa caggaaaaca gatctattat
    45181 tccaatactg gcaaaaacga agtgattcaa atattttctt ataacaaaaa taacaagcag
    45241 aacaagctac aattaactga tggaaaactc ccggaaaaac caaaccagct tgtattggat
    45301 gaaaaagcgg aagatgaagg gtataaaatc ggtgatattt atcagattga ttcagatgaa
    45361 ttgaaagaaa aagagtatac catcacgggc tttgtccgtt ctccattgtt catcaacaat
    45421 ttggagagag gatacgcgaa catcggaaat ggtagcgtcg attattttgt ctatttgcct
    45481 gaatccgctt ttaaaacaga tatttattct gtcttatatc ttgattttac aaacgtaaag
    45541 aatttgaata cgtacagcaa agcttacaaa gataaaatgg agcaaaatca agaaaaggca
    45601 gaaaagtatt tacaagatcg acccgaagaa cgcttagaag agctgaaaaa atcggccaac
    45661 gaagaattag aaccagcaca gcaaaaaata acagaaggca aagcacaaat agcacaggga
    45721 agaacacagt tagaagatgc taaaaaacag ttagcgcaac agtcagcagc tatccagcag
    45781 cttcctgaag cgcaacgaac aatcgctgtt caaacattat ctcaacaaga agctcaactt
    45841 gctgaacaag aaaggcaatt agttgagaaa gaacgtgaac tggcctctgc agaggaagaa
    45901 ttgaatcgaa atgcagaaaa aattgaaaat ttaactaaac catcatacct atacaatgaa
    45961 cgttcagaaa atgtcggttt tcaagaattt ggtgatctgt ctgatcgtat cgctgcgatt
    46021 gctaatgttt ttcctgtttt ctttttcttt attgccgcat tgatcacctt tacgacaatg
    46081 acacgtatgg tagaagaaaa ccgcagggaa atcgggacat taaaggcgtt aggttatacg
    46141 aaagttgaaa tcgcaaaaaa atatgcaatc tatgcaagtc tagcctcagg gataggcatt
    46201 gttttaggaa cgatattagg aacgaatctt ttgccaagga tcatttttga gctgtctaac
    46261 gagcggtatg atattgggag tgcgcttatt ttttatgact ggccgccgat tttacaagca
    46321 gctgccgcat tcttcattgc cgcatttggc gctgcaatga tcgttttatt caaagattta
    46381 agagaacggc ctgctgcatt gcttcaaccg aaagcaccga agccagggaa acgcattttt
    46441 cttgaataca tcactccgct gtggtcacgc cttagcttta atcaaaaaat cagttaccga
    46501 aatctcttcc gatataagtc aagaatgctt atggcgatta tcggaattgc tggatgtgcc
    46561 gggctgatgg ttgcaggcgt gggattaaaa gattctctaa gttctgtctc agccaaacaa
    46621 tttggaccga tcattgacta tcaagcaatc gttacattgg attcatccac ggaagatagt
    46681 cgtcaaaaag cagcggatat gctgcagaag caagaaaaag taaatgagat cctagctatt
    46741 catactcaaa ccgtagaatt gagaaaaaaa ggacatgctt cgcaaagtct gacagtgatc
    46801 gtaccaagta aaacagctga tttggatcgt tttatccatt taactgatct tgaagagaac
    46861 ccacgctcct tgcctaaaac aggaatcgct attacgcaaa aagcagcaga actatttgac
    46921 ttatctacag gagatcatat ttcgctttat gatgaagatc aaaaagaatg gaaagtcgaa
    46981 gtaaaagaaa tcgtgaaaaa ctatctaggt agctttattt atatgtcccc tgaatattat
    47041 gcttcagtta ctgatcaatc gatgatggat aatgcatttt tgctgcgtac agataagatg
    47101 acaacgaaag aagaagaaat gctttccgag aaactgcttg ccacagacgc tgtgacaaat
    47161 acgtctttca tgtccaaaca aatcgaaacg caagaagaat caatggcgaa cttagactcg
    47221 gttgtcttaa tctttgtcgt attatcagga ctgctggctt ttatcgtctt gtataatcta
    47281 actaatatca atatttccga gcgtgtacgc gaattatcta caataaaagt ccttggattt
    47341 tttgataaag aagtcacgat gtacattgtt cgagaaaata tcatctttac tcttttagga
    47401 atcatcggag gatttggtgt aggatatata ttgactgact tcatcttgca acaagcgtct
    47461 atggagaatg tcatctttcc attagtgatc acatggtggg cttatgtctt atcagcagga
    47521 ttaactatcg tattcacggt tattgtgatg atcgttaccc atttcaaatt aaagcatatc
    47581 gatatgattg atgcgttgaa atcgaatgaa taaaaacaga ggttgtgaaa tcagcggttg
    47641 tgaaaaagct gtcctgcatc gagcaaaaag aatactcaaa taaaattagc tcctcatgtt
    47701 ttacatttga gaagactgat tgccgtagat aaaagctttt gaacaccatt tatagaagaa
    47761 acaagaatat tttgctattt taaacaagag gatagacaaa tacatgtctg atctcttgtt
    47821 ttttattggg caacagacct cttagaatgt ataaagataa attttacaaa cgctttcggt
    47881 tcagttataa taataaatga taacttgtat atataagttg tggtaggtaa taaatcagtt
    47941 gaatggaggt aaatatccat gacatttaaa gacaaagtca tttaccaaat ctatcccaaa
    48001 tcttacaaag acagtaatgg tgatggaatt ggagatttaa aaggaatcaa agaaaaactc
    48061 ccgtatctga atgatctagg catcgacatg atttggctaa accctattta tccaagccct
    48121 caaaaagaca acggttatga tatctctgat tacacagcca tcgatcctat ctttggtacg
    48181 atggaggaat tcgaacagct aatagccgaa gcaaagaaat accggataga aatcatgctc
    48241 gatatggtgc tgaatcacgt ttcgacagaa catgaatggt tcaaaaaagc actagcaggg
    48301 gaccagcatt atcaggactt cttcatttta agagaagagc caacggattg ggtatcaaaa
    48361 tttggtggaa gtgcttggtc gccatttgga gatacgggga aatattattt gcacttatat
    48421 gatcggacac aagctgactt gaactggcgg aaccaagcag taagagagga actattcaaa
    48481 gttgttcgtt tttggatgga aaaaggggta aaaggattcc gtttcgatgt tatcaatgtt
    48541 atcggtaaag acgaacaatt gaaaaataat aaagaaaatg atggcaaacc tgaatatacg
    48601 gacaaaccaa tcacccatac gtatctaaaa gaattgaacc aagcaacgtt tgggacggat
    48661 tccactatca tcacagtcgg tgaaatgagc tctacgacga tcgaaaattg tatcttgtat
    48721 acagaaccta gtagagaaga attatcaatg gtctttaatt tccatcattt gaaagtcgat
    48781 tatgaaaatg ggaataaatg gtctactcct ccatttgatt ttgcagaatt aaagcgacta
    48841 tttcatacat ggggagaaaa gatgagtgag ggtaacggct ggaatgctct attttttaat
    48901 aatcatgatc agccacgtgc gctcaatcga tttgtagcta tcgatcagta tcgaaaacaa
    48961 ggagcagaga tgctagcaac catgatccat ttgaaccgtg ggacgcccta tatttatatg
    49021 ggagaagaaa tcggcatgat cgacccagac tattcatcga tttccgacta tattgacgta
    49081 gaaagtttga atgcttataa gttactcctt gaacaaggat tcacagaaaa agaagcgttt
    49141 cgtcggatca aagcaaaatc tcgcgataac tctcgaacac ccatgcaatg gtcagacaca
    49201 gaacaagcag gatttactac agggaaacct tggttaaaag ttggaggcaa gctagaagag
    49261 attaatgtag aaaaagaact atcttctgaa gattctattt tgtcctatta caagaaattg
    49321 attcggctga gaaaaacata tccaatcgtt gcacaaggag attatcatgc ttatgaagca
    49381 aatcatccgg aagtttatgg ctttcttcgc caatttgaag gacagcagct gcttgtatta
    49441 acaaatttct atgataaaga tacaaggatc gccatcccag aaggattcac agaagccaat
    49501 attcttatcg ataattattc cgatactgtt cttcatcaaa gtctggagct aaaaccatac
    49561 caggcaattg ctttgctgaa aaattaaaac aaaaacacaa aacgtcgttc ctacgagcta
    49621 ttctcgtaag atcgacgttt tgtgttttat ttaaaataat cttcttcaga aaatgaagag
    49681 ttttcatact ctcctttatc gccataaaat ttattgtagc gttgtttgaa tttacggaaa
    49741 ataaaagtaa cgagtaattt gactaacgta tagataggaa taccaaaaat aacgcccaca
    49801 attcccatta gatcacccat gacaagtaaa acgattaaga tcgtaatcgg atggatctgt
    49861 aaacgatcac ccattactcg aggaatcacc aagtcaccgt ggagaagttg tacggcaaac
    49921 cagacaatga caaatttgac agccataaaa gtagagtctt ggaatgcaat gatcaaacct
    49981 ggaaagaagg cgataaacgg cccaatatat ggaatgatac ataacaaccc agcagaaata
    50041 gctaaaacac tagcaaattc taatccgatc agtaagaaac aaacccagta gactgctcca
    50101 aggataaatg aagcaatgat ttgccccttt agaaatgaac ccaattgttg attagcaatc
    50161 tttgtcaaat ttttaaaatc tgtacgaaat gctggtggga caatcgctaa aactgactga
    50221 taaaattttt gaggatctct caaaaggaaa aaagcgacaa ttggaccagt aaataaagta
    50281 ataaaaatag ctgtaacagt tgaaaaaatg ttgctgatcc gttgtgcgcc actttcccaa
    50341 taatttccaa taaatccagc tatatcagac gtcacgtcgt caatagaagc gaaaaattga
    50401 ttaaatgaat cggcaaaagg tgttttctcc aaaaattgtc ggagactctc ttgaaaatct
    50461 tgaaacaaat ctggcaaact actgatcaat gtctttgcct gttcttcaag aaaaggaata
    50521 agccatatgc ttccaagccc caataaaaat aaaataatca cataaacgat aatgactgac
    50581 aagttcctcg aaaggtgctt gctcaaacgt ttgatgactg gttccaaaag ataatacaag
    50641 atcagtgcaa acaataatgg gggcaagata gtagcgataa tgattccgac aggcttgaat
    50701 ataaacgaga tctgatggaa aaaataaatg atcagcgcaa gtaagataac tattcctaaa
    50761 acatagtaag aggtttttcc tcctaaaaag cggatcaaac gattcgttgt atctgtttct
    50821 tttttcactc tttttcctcc tttatctata acttcattat agacaaaagc gggtataaaa
    50881 ggaaaatgat agaggttgat tgcaaaaata tcgtcaatca ttcatataaa ctttctcatc
    50941 aattaaaata agaaaacgct tgacagttct tttaaccata tgataaatta aatcctgttg
    51001 ctaaaacgta actattacgg tttgcgaaaa gcgaatcgga acattcaaat gaaagaagat
    51061 gagaagagga gtgtcataaa tgaaacgatt gataggtata ttggccatgc tggttttagc
    51121 aggtatgtta actgcttgcg gggcaagtgg gaaagccgag gacagtaaag aaaaattgag
    51181 cgtgatgacg accttttatc ccatgtatga ttttacaaaa gcaatcgtcg gggatgaagg
    51241 agaagtagag ttattgattc cagcagggac tgattcccac gattatgaac cttctgctaa
    51301 agacatggca aagatccaag atacagatat ctttgtttat aatgatgaaa acatggaaac
    51361 atgggtcccc gcaatccaaa aaacattaca agaaggcaat gtccatacga taaaagcgac
    51421 agaaggtatg cttttacttc cgggaagtga agaaggacat gatcatgacc atgaacacgg
    51481 ggaagaaggc catacacatg agctagaccc acatgtatgg ctagctccaa gtttagcaat
    51541 caagcaggta gcaaacatac gtgatcagct gattgaagct tacccagaaa aacaggaagt
    51601 atggacaaaa aatgcagcag cctataccga gaaacttcaa gcactccatc agctttatca
    51661 agaaaccttt aagcaagcaa aacaaagatc ttttgtcacg caacatgctg cattcaacta
    51721 tctagcgtta gaatatggat tgaatcaagt atcgattgct ggtctttctt ctagtgaaga
    51781 accgtctgcg gcgagaattg ctgaactgaa acactttgtt aaagaacatg gaatcaacta
    51841 tatttatttt gaagaaaacg ccaaagatag tattgccaga acgttagcaa acgaagcagg
    51901 tgtatcttta gaagtattga atcctttgga aggattgacg aatgaacaaa tagaaaatgg
    51961 agaaaactat ctttctatca tggaagcaaa cctcgaagcg ttgaaaaaaa cgacagagac
    52021 agaaaacccg ctagaagata ctttgacccc caaaaaagaa aagagcgtct acaacggtta
    52081 ttttgaagac gaggatgtac aagatcgctc tctttcagat tgggcaggaa cttggcaaac
    52141 agtagatacg tatgtagaag atgggacttt tgatcctgtt tttgaatata aagaaaaatt
    52201 gaatcaggat aagacagcac aagaatataa agaatattat acgaagggct atcaaacaga
    52261 tattgcttca atcaagatca gtgagaaaga gatggcattt acgtttaaga atggaacaac
    52321 gaaacgttca aattatcgtt atgtagggaa agaaatcttg acctacgagg caggaaaccg
    52381 tggcgtaagg tatctattcg aagcagaaga taaggaaagt ggcgctttta gatatattca
    52441 attcagtgat cacacgattg caccggctga ctccgaacat tttcatttat atgcaggaaa
    52501 tgaaagtcaa gaagtattgc tgaaagaaat ggagaattgg ccaacatttt atccagatac
    52561 aatggatgga cgtgaaattg cacaggaaat gcttttgcac tgataggcaa aaaagaaccg
    52621 aagggtttgg atcggctggt catttagtcg gtccaaacta ttcggttctt tttatgaaat
    52681 caatttcttt aatccacgga tagaggctgg gatggtctcg ccgtttgcca acgtgacttc
    52741 tctggttttt ttattaatcg accgcacatt ttgtgtattg ataacatagg atttatgaca
    52801 acggataaaa ttccgatgca ttttctcgat ttctttgatc ttctcataga attgtaattg
    52861 ggcatgagtc aaatggactt ccagtttatg tggcgctcct agcgaagtag aaaaatattg
    52921 gatgtctttg atcggtaaaa atttgatctc atcattaaac tctattttga agatatcttt
    52981 ttggatttgg gacatttgaa aatcttcgaa aattttgctc aggatatgct cgacattttc
    53041 ttttaaatca taaagatctt ctttgacgat ataatcagtc ggttcgatgt tgctttttaa
    53101 gattttcatc gacatttccg tatgggaagt cacatagatt atttttccta aaggatctaa
    53161 ttcacggatc aatttaccga tcgctacacc atccatttca ctgtcttcta gttcgatatc
    53221 taaaaagtaa ataccaaaag aagaagttct gatcttggct gcattgagaa gttcttccgg
    53281 atcagaggta gaaatatgga cataactgtc taagttttca atcatgattc tatttttgat
    53341 caccgttgat aaaacttcta attgttttgg atcgtcttca caaatataaa tgggaatcat
    53401 atcattactc ctttatttta tttgtatacc cgtggtgcta gttaattttt tcctagagga
    53461 aaatgtctaa acatgttggt aaatcaacaa a
//
LOCUS       DAZULR010000019        50033 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.019, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000019 DAZULR010000000
VERSION     DAZULR010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 50033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50033
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.019"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            198..1418
                     /locus_tag="ACG8ZV_001223"
     CDS             198..1418
                     /locus_tag="ACG8ZV_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HFS4996575.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            1415..4135
                     /locus_tag="ACG8ZV_001224"
     CDS             1415..4135
                     /locus_tag="ACG8ZV_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFS4996576.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            4119..5063
                     /locus_tag="ACG8ZV_001225"
     CDS             4119..5063
                     /locus_tag="ACG8ZV_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFS4996577.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(5132..6142)
                     /locus_tag="ACG8ZV_001226"
     CDS             complement(5132..6142)
                     /locus_tag="ACG8ZV_001226"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFS4996578.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(6322..6666)
                     /locus_tag="ACG8ZV_001227"
     CDS             complement(6322..6666)
                     /locus_tag="ACG8ZV_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HFS4996579.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(6659..7093)
                     /locus_tag="ACG8ZV_001228"
     CDS             complement(6659..7093)
                     /locus_tag="ACG8ZV_001228"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HFS4996580.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            7231..7968
                     /locus_tag="ACG8ZV_001229"
     CDS             7231..7968
                     /locus_tag="ACG8ZV_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4996581.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            7961..9172
                     /locus_tag="ACG8ZV_001230"
     CDS             7961..9172
                     /locus_tag="ACG8ZV_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4996582.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            9376..10158
                     /locus_tag="ACG8ZV_001231"
     CDS             9376..10158
                     /locus_tag="ACG8ZV_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HFS4996583.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            10228..10890
                     /gene="trmB"
                     /locus_tag="ACG8ZV_001232"
     CDS             10228..10890
                     /gene="trmB"
                     /locus_tag="ACG8ZV_001232"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HFS4996584.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(10988..12742)
                     /gene="ade"
                     /locus_tag="ACG8ZV_001233"
     CDS             complement(10988..12742)
                     /gene="ade"
                     /locus_tag="ACG8ZV_001233"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000034 - adenine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006146 - adenine catabolic process
                     [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HFS4996585.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            12874..13803
                     /gene="comGA"
                     /locus_tag="ACG8ZV_001234"
     CDS             12874..13803
                     /gene="comGA"
                     /locus_tag="ACG8ZV_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus ATPase ComGA"
                     /protein_id="HFS4996586.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLKLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            13760..14809
                     /gene="comGB"
                     /locus_tag="ACG8ZV_001235"
     CDS             13760..14809
                     /gene="comGB"
                     /locus_tag="ACG8ZV_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus assembly protein ComGB"
                     /protein_id="HFS4996587.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            14806..15084
                     /gene="comGC"
                     /locus_tag="ACG8ZV_001236"
     CDS             14806..15084
                     /gene="comGC"
                     /locus_tag="ACG8ZV_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus major pilin ComGC"
                     /protein_id="HFS4996588.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            15059..15529
                     /gene="comGD"
                     /locus_tag="ACG8ZV_001237"
     CDS             15059..15529
                     /gene="comGD"
                     /locus_tag="ACG8ZV_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGD"
                     /protein_id="HFS4996589.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            15501..15848
                     /locus_tag="ACG8ZV_001238"
     CDS             15501..15848
                     /locus_tag="ACG8ZV_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996590.1"
                     /translation="MVAIQKELNKTGFVLLESLTALMIASVCVYLVSFGQLFLLQAEK
                     KSGEELLFIRMIYEDIKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAI
                     SIEKTSNSSIYAD"
     gene            15811..16236
                     /gene="comGF"
                     /locus_tag="ACG8ZV_001239"
     CDS             15811..16236
                     /gene="comGF"
                     /locus_tag="ACG8ZV_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGF"
                     /protein_id="HFS4996591.1"
                     /translation="MKKQVIPAFTLIECLIGLMILSSLLLTFNLLIQQTIQVSEFLQR
                     KDQKEWLIFLAQLEEELKSSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQ
                     PMLTSITELQLLEKEHTISFYVHFENGEDGYAIWTKNDQ"
     gene            16208..16567
                     /gene="comGG"
                     /locus_tag="ACG8ZV_001240"
     CDS             16208..16567
                     /gene="comGG"
                     /locus_tag="ACG8ZV_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGG"
                     /protein_id="HFS4996592.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            16739..17746
                     /locus_tag="ACG8ZV_001241"
     CDS             16739..17746
                     /locus_tag="ACG8ZV_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFS4996593.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            17771..18955
                     /locus_tag="ACG8ZV_001242"
     CDS             17771..18955
                     /locus_tag="ACG8ZV_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate/propionate family kinase"
                     /protein_id="HFS4996594.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(19392..20975)
                     /gene="abc-f"
                     /locus_tag="ACG8ZV_001243"
     CDS             complement(19392..20975)
                     /gene="abc-f"
                     /locus_tag="ACG8ZV_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protection-like ABC-F family protein"
                     /protein_id="HFS4996595.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(21080..21208)
                     /locus_tag="ACG8ZV_001244"
     CDS             complement(21080..21208)
                     /locus_tag="ACG8ZV_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996596.1"
                     /translation="MMRMTKITSNENYQRYHIAFSHAIGFTVAVDGTSLSKTVEFT"
     gene            complement(21553..21696)
                     /locus_tag="ACG8ZV_001245"
     CDS             complement(21553..21696)
                     /locus_tag="ACG8ZV_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HFS4996597.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(21918..22397)
                     /locus_tag="ACG8ZV_001246"
     CDS             complement(21918..22397)
                     /locus_tag="ACG8ZV_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFS4996598.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(22470..22754)
                     /locus_tag="ACG8ZV_001247"
     CDS             complement(22470..22754)
                     /locus_tag="ACG8ZV_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996599.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(22832..23026)
                     /gene="ssrS"
                     /locus_tag="ACG8ZV_001248"
     ncRNA           complement(22832..23026)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="ACG8ZV_001248"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(23098..24384)
                     /locus_tag="ACG8ZV_001249"
     CDS             complement(23098..24384)
                     /locus_tag="ACG8ZV_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HFS4996600.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            24522..25193
                     /locus_tag="ACG8ZV_001250"
     CDS             24522..25193
                     /locus_tag="ACG8ZV_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HFS4996601.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            25159..25647
                     /locus_tag="ACG8ZV_001251"
     CDS             25159..25647
                     /locus_tag="ACG8ZV_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HFS4996602.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            25660..26607
                     /gene="prmA"
                     /locus_tag="ACG8ZV_001252"
     CDS             25660..26607
                     /gene="prmA"
                     /locus_tag="ACG8ZV_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HFS4996603.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            26608..27372
                     /locus_tag="ACG8ZV_001253"
     CDS             26608..27372
                     /locus_tag="ACG8ZV_001253"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HFS4996604.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            27605..29818
                     /locus_tag="ACG8ZV_001254"
     CDS             27605..29818
                     /locus_tag="ACG8ZV_001254"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HFS4996605.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            29829..30275
                     /gene="dtd"
                     /locus_tag="ACG8ZV_001255"
     CDS             29829..30275
                     /gene="dtd"
                     /locus_tag="ACG8ZV_001255"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HFS4996606.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            30446..31705
                     /locus_tag="ACG8ZV_001256"
     CDS             30446..31705
                     /locus_tag="ACG8ZV_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004497 - monooxygenase activity [Evidence
                     IEA];
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HFS4996607.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(31794..32741)
                     /locus_tag="ACG8ZV_001257"
     CDS             complement(31794..32741)
                     /locus_tag="ACG8ZV_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFS4996608.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            33135..34427
                     /gene="hisS"
                     /locus_tag="ACG8ZV_001258"
     CDS             33135..34427
                     /gene="hisS"
                     /locus_tag="ACG8ZV_001258"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HFS4996609.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            34442..36211
                     /gene="aspS"
                     /locus_tag="ACG8ZV_001259"
     CDS             34442..36211
                     /gene="aspS"
                     /locus_tag="ACG8ZV_001259"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HFS4996610.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            36320..37195
                     /locus_tag="ACG8ZV_001260"
     CDS             36320..37195
                     /locus_tag="ACG8ZV_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFS4996611.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            37461..39344
                     /locus_tag="ACG8ZV_001261"
     CDS             37461..39344
                     /locus_tag="ACG8ZV_001261"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFS4996612.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQISNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(39419..39703)
                     /locus_tag="ACG8ZV_001262"
     CDS             complement(39419..39703)
                     /locus_tag="ACG8ZV_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFS4996613.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(39693..40427)
                     /locus_tag="ACG8ZV_001263"
     CDS             complement(39693..40427)
                     /locus_tag="ACG8ZV_001263"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HFS4996614.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            40556..41179
                     /locus_tag="ACG8ZV_001264"
     CDS             40556..41179
                     /locus_tag="ACG8ZV_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HFS4996615.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            41371..42492
                     /locus_tag="ACG8ZV_001265"
     CDS             41371..42492
                     /locus_tag="ACG8ZV_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HFS4996616.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            42499..45627
                     /locus_tag="ACG8ZV_001266"
     CDS             42499..45627
                     /locus_tag="ACG8ZV_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFS4996617.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKAEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTALVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            45646..48840
                     /locus_tag="ACG8ZV_001267"
     CDS             45646..48840
                     /locus_tag="ACG8ZV_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HFS4996618.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYAEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKSKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(48986..49693)
                     /locus_tag="ACG8ZV_001268"
     CDS             complement(48986..49693)
                     /locus_tag="ACG8ZV_001268"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFS4996619.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
BASE COUNT        16310 a         8804 c        10436 g        14483 t
ORIGIN      
        1 gtcaaacgaa gcgaatataa catagatatt taggattgtg acaaaaatca tgtcacaatc
       61 tttttttcga ataaacttat tttttgaagt cggccattta tcgtaatttc tttgcataat
      121 acgaacaaat tttcggttat tgatgaaaaa aaacattgaa aatggtatga taaaagaaaa
      181 aaaggaggaa atttttaatg gtgaaattta tccatgcggc agatttacat atggatcggt
      241 catttgaagg actgacaact cttgataaaa ctgtacagga aaaactattg aagacgaatc
      301 tgaccgtttt atcaaatatc attgaacagg caataataaa taacgttgat tttgttttac
      361 ttgcaggaga taattttcat caaaatcgtc cttcattaaa aatacagaaa catttttcag
      421 aacagatgaa acggttagaa aagaaccata tacctgtatt tataatattc ggaaatcatg
      481 atttctatca aaaagagcgg tattggttct cctttcctaa aaatgtccat ttatttacat
      541 ccgaaacggt agagacaaaa aaaataacga taaaaagtgg agaaactgtc tctctcagtg
      601 gatttagtta tcgtcaaccg tggattcaaa aagacaaagt gatggaattt ccttctagag
      661 aactcacaga ttaccatatt gggttgtacc acggggaacc tggcgtctct caaaaaggaa
      721 actatgctcc tttccaaccc tcaaagatgc aagaaaaggg atacgattat tgggctttag
      781 ggcatatcca tgtgccaacg gtcttaaatg aaaagcaaac aattgtttat ccaggtgcgc
      841 ctcaaggtca tactaaaaag gaacaagctt ctacatctat tctactagtt gaattaagta
      901 aaggaagttg ccaaatacat ccgattaaag tagcagaggt ctattggaag acaaaggaaa
      961 tatcattgag gaaagcaaga acgacaaaag aggtcattgt tcacattcgt cagcagcttt
     1021 caaaagtaga ggatggattt agtttaattg agataaaatt aaaagattat gaccatctca
     1081 atacagatgt tttggaacgg atacaatcag gagagctatt agactatttg ttagaggaat
     1141 tctcagatag gataaatgat ttctttattt ggcgtatttc tctcatagag aatacttttt
     1201 atacgaagac cccacttgct gcttctgcta aattgatgga acagttattt caatactatc
     1261 agacacctca agatttccaa caaattttaa atgaagtata tagtcatcaa gaagcggcta
     1321 gaatattgag cgaactgccg gaatatcaag aagaaacact tgaaaaagcc aagcagctgc
     1381 ttaatcaaga ttttttattt gaggaggatc aggaatgaag attttaagga tcgagattgc
     1441 tgcttttgga aaatggcgtc aaaaaagttt tgacttttat tcaggcaatc agctgatcta
     1501 tgggggaaac gaagcaggaa aatcaacgat ttatcaattt attcaagcaa tattatttgg
     1561 tttcccttca aaaggccgta aaaaaaagga ttatacacca aaagacggct cagcctatgg
     1621 cggcaaaata tggcttaaac atcctgtata tggtgaattt gctgtcgagc gctacaagca
     1681 gcaaaatcgc ggaaaatcga aggtgtggct gggggatcaa gtgggaagtg atgagttact
     1741 agaaaaactg atcgcacctt tgacgaaaga gttattccag caggtattta ctttccagca
     1801 agagcagttg atggaactag atcatttgag agaaaaagag ctacatgatg cgctgatttc
     1861 tttaggcatc acgggcagtt ctcaagtatt ccaaaagcgg caagaatatt atcagaaagc
     1921 acaacaatta ttcaagaaaa aaggccaaaa attactaatc aatcaaaaat taaatgaatg
     1981 gaaagagctg caagaaaaaa ttcatcaaaa acaagaacag gaagcttatt ttggcaagtt
     2041 gatccaacaa gaacaggaat acgagtcgca acagcagcag ttattggcac aattaaaaga
     2101 ggcgaacaaa caattttcat tagccagaca gcaagaactt aatttttctt tatatgaaga
     2161 atggcaatct ctcaaaaaaa acagcactac aggtcttcct gatgagcaac ttcttttaga
     2221 tctggagtct ttctccaaac ggtatcagca aacaaatgag cgtttggaag aattagaagc
     2281 aacactggaa aagcatagcg ggatggatca gcagtcagcc agatattatt tttatttaga
     2341 gcaggagcag gaactaaaag atctccagca acttcaattt acagcggaac aattaaacga
     2401 agaatggcaa agattacaaa ttgagactag agaaacaaat tcagaattga agattttgga
     2461 acaaaggtgg cattggcaga aaaatccgtt accggaagaa tttttatatg aagaagaatg
     2521 gaagcatctt ctggctgaag aaagaaggat tgctgatcta gaaagccaga tttctgtgcg
     2581 tctccaaata gctaaagaac agcaagagat gattgaagca gaagtgaatg acttggaaga
     2641 gacctatcca gcattattac aaaatcagtc agagatagca ccagtctctt catctaaacc
     2701 gtatatgctg atggctggcg gagcaataat cattgcaggt atatttgtac caatgccctt
     2761 gaaagtgatc cttttactaa ttggtgcagg catgattggc tatttcttct acaaaaggca
     2821 accaaaaatt aaaactaaaa atgatttctc tgagataaaa ggaatgtggc aagaaaaact
     2881 aggacaactt gatctagcct tagctcaatt agctgaagca gaagaaaaac aaaagagaac
     2941 tggagaagaa aaacagattc ttcagcaaga agtatatcgt tttgcggatc atcggcactt
     3001 aggaaagatg gatacgctca aactcatgaa agaatatgga caggaagtca tagattatca
     3061 gaaattatat ggcgtatttg agcggaaaca taaaagagaa caggaaatac aagaaaaact
     3121 acgacaaatc gaccaaaaat ttgagtttgt taaagaatgg ttaccgatac aagataagac
     3181 aatttcagaa aaaatggtat tgctttcccg ttttatacaa gagatggaac agatgaaatt
     3241 tgccagaagc tatcagcaaa atactttatt gaagcaagaa atcaatcaat tgaaaaagaa
     3301 acaaaaagta tggatacaag aatacagcga acaattgact caagcaggct tatcttatcc
     3361 ttcggaagta cctgtctttt tacaaaaagc caaacaagcc gaacagcaga tgaaaagata
     3421 caatgaatta tcggaaatgc ttactccact atttcctgaa gagctgacaa aagagaaatt
     3481 atctgtaaga ctgcgccaac tgaaagaaaa gcaatcccaa ctccagcaag aagaaaaaga
     3541 agcaagtgaa aatcggcaac gactccaact tcaagtagaa gagttgcaaa gagacggcac
     3601 attggacgaa ctttatcaac aagctagccg gcaaaaagca aaattacagg aattactgga
     3661 ggaatgggga gcacttgaaa tcgccgggac attcttaggt gatctttcaa cagagatgag
     3721 tgaaagacaa ttaccccagt tgttaagagc agcaggtgat tatttaggta ttttaacaaa
     3781 aggaaattat cagaagatat tactgaaaaa tgatacactg actttaacag acggatatac
     3841 agaatttccc atctatgagt tatctacagg tacgaaagat cagctgatta tggcgatgag
     3901 atttgcttac ctctcattag aagctaaccg ttcgatatgc ccgatcatca ttgatgatgg
     3961 ctggcttcat tatgatcatc agcgaaagta tcaattagct gaacttttag ctaaatttgg
     4021 agaaaagtat caaataattt gtttttcttc tgataaagaa atggtaagct attaccatga
     4081 gatgaaccaa atcgtaaaac aattagaagg agcaaataat gaaaaaaatt cgtgatttag
     4141 taatcgatga gcagtttgaa caatttgtcc tgatcaaaag tgcagatgta agaatcgcta
     4201 aaaacggaaa aaaatttatt gcttttactt tccaagatac ttcaggtact atcgatggta
     4261 aatactggga tgcttcggag gaggaaatca ataaatttac agccggcaca gtcgtttttc
     4321 taaacggtaa aagagaggtt tatcaaggaa accctcaagt aaagattctt catatgcgct
     4381 taacaagggt agatgagcca ggagagccta gtttatacat ggaaagagcc cctttgaaga
     4441 aagaagaaat ggaagaagaa atcaatcaat tgttgtttga gatcaccaat gcgcattgga
     4501 atcgtattgt tcgctatcta cttaataaat atcaaaaaca attttttgag tttccggcag
     4561 caaaaagaaa ccatcatgca tttgccagtg gattagctta tcatactttg acaatgcttc
     4621 acttagggaa atcaatcgcc gatgaatatc ctgagctgaa tcgagcattg ttgtatgctg
     4681 gtatcatttt gcatgattta ggaaaggtga ttgaactttc cggtcctatg tcgacagaat
     4741 atacgcttgc aggaaatttg atcggtcatc tggtattgat tgacgaagaa ataactaaag
     4801 cctgtcttgc gttgaaaatc agcgaagctg acgaagatgt tcttgtatta cgtcatatgg
     4861 ttttagcaca ccatggctta ttagaatatg gctcacctgt acgtccaaga ataatggaag
     4921 cagaaatatt acatcaaatc gacaatatcg atgcttcgat gcagatgatg ttgacttcga
     4981 ttcgtcaaac agaaccagga aaatacaccg atcggatttt cggtatggac aaccgaagtt
     5041 tctatgtacc aaaagattta tagcaaaaat ttattttttt cattcaaaac aaaaaaagcg
     5101 agacataagt cttcgctttt tttgttttct tttattttga tgaatcagtt gtttcttcag
     5161 ttgaagattc ttttgttgaa tcagttgatt ttgtgtcaga actctttgtt gaagctgtag
     5221 tttcacttga gtctttcgta cttgatgaag ttgttgtgaa tgcactcaac acattttcaa
     5281 aggcatcatc tttgattttt acatttgcat cttttaattc ttcaccgatt actttagttg
     5341 tgaatgcatt gtcacttagt ttagtttcag tagcgatatc ttttagttga tctttgtatt
     5401 tatccatgtc attgccttta ttttggtttt tcaccatttt gacaacgtag tattctgtcg
     5461 cataagaagt aggatttgtt gtagtaataa catcggagat ctcaccgtct ttcaatttga
     5521 aagctgcttc ttttacttct gcaggaatag ttgttgtcgt tgagtcgaat ttaactttac
     5581 cgccatcttc ttttgtctct gtatcagttg atttgtcttt ggctaattta gagaaatcat
     5641 ctccatcatc cgctgatttt ttcacatctt ttgcttcatc ttcacttgat aatttgatga
     5701 tttgtgcttc tacttctgga tggaaagatt tccaagcagt tttcaaatcg tcatctgtaa
     5761 tatctacgtg agctttcaag ccagcttcaa aagctaaatt gttacgaata tattctttat
     5821 aagtatcttt cgtatatcca gcagcttcta attgtgattc aaaagtatca cctaatgatt
     5881 tcgcttgttt gtcgtattct gcatccactt gcttatcggt tactttatcg ccatatttgt
     5941 tattgaatac tttataaatg atcatccgtt gtactaagga ttggttcgat gattcaagtt
     6001 ttgcttcatc atagaaatca gatacagtga tcgttccgcc tttcatcgtt gcgatatctt
     6061 tattagtatc gcctgaacaa gctgctagag ttaaaacagc caacgcacta gtagctgcca
     6121 aaataattga tttttttttc attaaaattt gcactcctgt aattagttat tatttttata
     6181 tattaactat accatatccc atttccttta aaaacgttgt cgtggtagtt tcaaacaaaa
     6241 ttcaaaattt catcacattc ctaggaaata cgcaaacttt tctcacttat atagttaaat
     6301 ctgttgagaa aataatcatt attatatttg ttcaggatac tctggcagat cagcttttag
     6361 tttttctact tgttcattga tttgtgtgat acgtggttcg gcttggaatt taaaatcttc
     6421 gatatctttt ttgattgctt cttggaaagc aggaatcaca gattcagctg tttcttttgt
     6481 ttcgatcaat gcgcttttaa aatgattcag gctgttattt aaatcatttg tcagagttgt
     6541 tgcttcttcc aattcttcga tcagtttctt tcttgtttca ttcccgctcc tgggcgccaa
     6601 taacagacct ccgacagtgc cagcagcagc tccaaataac agtcctttga aaaagttttt
     6661 aatcatcgca ggacacctgc tttacgattg tttcttgaat agcttttagt tcttccgatc
     6721 cataactatc ttgatgattg acaaagtgaa tagaaaaatc atcctctttg ctgtagcgag
     6781 ggactaaatg gatatgtgaa tgaaaaacag attgataggc tagttcacgg ttgttattca
     6841 agatattaag acctttcatt tctggaaaag ctttttccaa tgcttgagca atcttaggca
     6901 cacgcgaaaa aacctctcct gcaagttcgg gatcatattc aaaaatatct gctacatgac
     6961 gtttaggcac aactaatgtg tgtcctttcg ttgcttgaga gatgtctaaa aaagcataga
     7021 ccttgtcgtc ttcatatatt ttatagcttg ggatttcttg attgatgatt ttgcaaaaaa
     7081 tacagttttc catataaaac atcctttcta taaagaataa atacttcagc ttaactttac
     7141 cataagttaa agctattgta aggaaaaaaa caaaataccg tcattttctt cgtggtataa
     7201 taaataaaaa taaatggcgg aggaaaaaga atgagtttaa ttatcgatca tgtcacaggg
     7261 gggtacggac atctccctgt gttaaaagat atcagtttcg atgtacagcc tggagagata
     7321 gtagggttga ttggactgaa cggagcaggg aaaagtacga ccatcaagca cattatcggt
     7381 ctgctggaag cttcaaaagg aacgatagaa atcaatcatc tatccttaaa gaaaaatacg
     7441 gaagaatatc gcaaacaaat tgggtatatt ccagagactc cttctttata tgaagaattg
     7501 acattgagag aacatatcga agtcactgcg atggcctacg atatacctat ggatatagca
     7561 atgaaaagag cagaaaagtt gttggagact tttcggttat ctaatcgtct tgactggttc
     7621 ccagctaatt tttcaaaggg aatgaaacag aaagtgatga tcttatgcgc ctttttgatc
     7681 gagccttctt tatatatcat cgacgaacca tttttaggct tggatccact agctatcaat
     7741 gcattgcttg aattgatggt agaaatgaaa aaagaaggag ccggtatttt gatgtctacg
     7801 catattttag ctactgcaga aaaatattgt gatcgttttg tggtcttaca taacggagag
     7861 atacgagcag acggttctct tgagatgttg agaaaagaat ttcagctgcc ggattcttct
     7921 ttggacgaaa tctatattgc tttaacaaag gagcaggcac atgagtagtt tttttcaaaa
     7981 acgtttagca agacatcaaa agaaaatgat gaaatatatg cgttatgtat tgaacgatca
     8041 ttttgtttta gtttgtcttt tcttgattgg cggtgtggga ttatattatt ctaattggtt
     8101 gaaaaccctg cagccaccgt ttgcaattgg agggctcata atctctgtat tttggatgct
     8161 ctgtttattc gtgggtaaga tggctacttt tgcagaggca gcagatattg tttttttact
     8221 tcctaaagaa aaagaaatgc aaacctattt ggaacgagct tttcgctatt cttgcatttt
     8281 tccgttgatc tttttgatat tggcatgcgg attggccatg ccattagtgg tggttagtac
     8341 ggagcaatcc ttttcgatgt ttttcgtcta tctgatcata ttatggagtt tgaaattcag
     8401 tcatctgcaa atcaagagag cagaattgtt tcgactagat caacaagtta ttcgttattg
     8461 gaaattaggc tggttttttt cttctctgat ctttttgttt ctatcatttt attggctaat
     8521 atgggcagga atagcaggtg cattagtaca ggcaagtcta tattactggt ttttgtggaa
     8581 gcaacaagaa aaaggattgg attgggagaa aatggtgcat gtagaagaac ataggttgca
     8641 tcagatctat caatttatca atttattcac agatgttcct gaaattacgg caaagatcaa
     8701 aagaagacgc tatttggatc ctatattgac tcatattaaa agagaatcaa aaaacactta
     8761 tctttacttg tttgcaagaa gattggcaag aggttctgat tttagtggtc tttatttccg
     8821 attagtaatt ataggtgggt tattgattgc cggagtagtc gacttttatt ttagtctgat
     8881 tatcggtttc ttatttttat atttgatcgg tttccaactg ttacctttag cgaaccagtt
     8941 ccgctatatg gttctcgttc agctttatcc aatccataag aatcagaaga agcaggcgat
     9001 tcagtatcta ctcacatggg tattaattat cgcgtcggtt atttttggtt tgattgctgc
     9061 agtcgtatta gatgggcagc agcgatgggt tccgctagcg gcttatttga ttgttactat
     9121 gctctttgtt aaactatatg taccaactcg tttgaagaag atgtcagact gaaaacaaag
     9181 ctgtgtaggg taaaaatgag aatgaaaaat agagcgttga cagtaagaat gctgttcgtt
     9241 ctattttttt tgagaaaagc tggttttttg aatggcaatt aaatgaaaaa gaacgtatat
     9301 gtgcttgacg tgtagtgttc aggcgactag aataataagt actgcaaaac aaagagtaag
     9361 aggacgggag aatgcatgat ggagtttcag ttagaccaag agtggcggtt acgtcccatc
     9421 aaaggcgaca caggaaaaac atacataggc atgcgtgatg aggacaaagt ctttattaaa
     9481 cgaaacacga ctccgatgtt ggctgctctt tcaagggaag gaattacacc aaaacttgtt
     9541 tggacaaaac gaacggggaa tggcgatact ttgacagcac aagagtggct ggaaggtcgc
     9601 ttgctgactc ctaatgagat tggtcaaaga aacgacgtga ttgatgtttt gtaccattta
     9661 catcattcaa attctcttaa aaccatgctg acccgtatcg gtggtcgtgt catgacgccg
     9721 gagaagatgc tgcaaaaata tgaaaaagaa ttaccggaag aactccagaa aaatcaattt
     9781 ctgcaaattg tccatcgttt tcttcgtgag cagatcccgt caatagataa ggaaaactta
     9841 tcagtagtac acggagatgt aaaccatcgt aattggttag tatgtaaaaa ttatttatat
     9901 ctagtcgatt gggattcaat catgtttgca gaccctgcgg tggatattgc aacgatttta
     9961 ggaaattatg tgccactgtc tagctggaat cagtggctga tcagttatgg catacgcccg
    10021 actgacgaaa tgcttgaaaa atttcattgg tatgcggcca tgaatttgct ccaagaaatc
    10081 accagatatt gcaaacgtga agatcatcga cggatgaacg aagaaatttt acaattaaaa
    10141 cgaattttca gtggctgagg tttggcccaa actctgcgga gatttggcca gaccttttta
    10201 attagaggaa aggaatggag ataaataatg cgtgtccgaa atcgtccggg agcagcggaa
    10261 atgttagcgg ctcacccgaa ttttgtaatt agtgatccaa cattgtggaa gggaaaatgg
    10321 aatgaattgt ttgaaaacga tcatccaatc cacattgaga ttggtatggg gaaaggccag
    10381 ttcatcactg gaatggcaaa agcccatcct gaaatcaatt atattggagt agaaatgcag
    10441 gtcagtgttg tttcgattgc actagacaag ttgatcgaac aaccgcttcc taacctgaaa
    10501 cttctacatg tggatggatc agcgttgaca gagtatttcg ctgacagcga agtagatcaa
    10561 atctatctga atttttccga tccatggcca aaaaaacgtc atgaaaaacg gcgattgaca
    10621 tataagactt ttcttgctgt agatgaacag attcttcgtc caaatggaga aatccatttc
    10681 aaaacagata atcaaggatt gtttgagtat tctctggcaa gtttttctca atatggcatg
    10741 atcctcaaac aggtatggtt agatttacat caaagtcaat ttgaaggcaa tattatgacg
    10801 gagtatgaag aaaaattttc ttcaaaaggt caacgtattt atcgagtaga agctcaattt
    10861 caagataaga ccaaaaagaa aagtctgtga aactaacttt ctgctttcat aaaaacatta
    10921 atatccataa ataaatctca gaaaatgaac attacagatg taatgtattt tctgggattt
    10981 atttgattta aaatgtattt atttcatcgg tttttccaca aggtggaatc aattggaagc
    11041 gagaaaatga aaataatcct ttgtcggtga tcttcaattc gggtatgaca gataatgtta
    11101 agaaagaaag tgtcaaaaaa ggatcaaagg ttttagctgc tcctagttga tgtgctttag
    11161 ttattaattc attcaactgt tcatagacga tcgaaaaagg ttcctgtgtc atgattccgc
    11221 ctataggaag agaaacacaa gctatttcct gctgtttgtt gacaacggtc atcccgccac
    11281 ctttttgaat caaaagatta gcagcataca gcatatcctc gtcgtttgtc ccaacgacaa
    11341 ctagattatg cgagtcatgg gcaatcgttg tcgctatcgc tccttgtttc agctgaaatc
    11401 ctttcactat gcctaatcca atgtttcccg tttgatggtg acgctcgatc accgcaatct
    11461 ttaattggtc tttttcgatt gaaggaatga atcgttcgcc ttgtcggtcc actttttcta
    11521 ccaaatcttt agtcactaga ctattcggga taatttcgat cacatgggct tgtgaagaag
    11581 aaagaagcag ctctaacgaa tgtggattta atggttgagc gtttagtttt ggcagacaac
    11641 acgtatatga atttgaatga tcagcaaata aatggtcttg gagttgccca gattgaacaa
    11701 ctaatgttcc cttatagaaa acttcatgaa ttggcagctt ggtaagatcg tctgttaaga
    11761 agaaatcagc ttgataccca ggggcaatcg cacctagtgt tttcaaatca aaacattctg
    11821 ctgcattcaa tgttgccatc tgaatggctt gtaatggatc gattccaagt gcaatagctt
    11881 gacggacgat atgatcgatt gatccttctt ttactaaatc attgatcagt ttatcatcgg
    11941 tgacaaagaa gcatcttctt gaattttcag gtgtgatcgc cggtagtagc gatgccagat
    12001 cttttgcaac ggtcccttct cgaaccatta aatacatacc aagatccaaa cgttctttag
    12061 cttcttttgc agttgtagct tcatgatccg tccgaatacc tgctgcagga taaacattta
    12121 actcttccat gccgatacca gctgcatgcc cgtcaatttt tttcttatgc tggtgcatca
    12181 attggatctt ttctaggatg tctgtttcat tatttgctac tgcttgatag ttcatgactt
    12241 cagctaagcc taaaacttcg ggtttttgta aaaaaggggc taattttttt gcatttaaat
    12301 ttgcaccatt ggtctcaaaa ggggttacag gtacacaaga aggtagcata aaaaagatat
    12361 tcatgagtgt ttgtcttgca tcttctatca taaactcaag acctgtactc ccagcaatgt
    12421 ttcctatttc atggggatct gtcactacag tagtaactcc atgaagcaag gatacttttg
    12481 aaaattcgct tggtgataaa agtgagcttt cgatatgcac atggccatcg atgaatcctg
    12541 gcactagata ttgcccatta gcattatgta cgctttttcc ttcgtattca ccgattccta
    12601 cgatcattcc ttcgcagatt gctacatctt tttccatgat ttctttcgta aagacgttga
    12661 cgatcttagc atgcttgatc actaggtcag caggcttttt tttacttgct acttcgatat
    12721 atttccttaa tgttgtttcc aatggagtgc ctcccaagat aaatttttat aagtataaca
    12781 taaattcggc ttttgccaat atttttttgt aaattcattt tatttgaaac aaaaagatca
    12841 aaaagacgta tgttttttgt ggaggggaga ataatggaaa taaaacgatt atcggatcaa
    12901 atgataagtg aaagttttgc caaacatgcc caagacgtat atatattgcc agcttcagaa
    12961 gtattttaca tctattttcg ctatggaaaa aaacgaacat tctggaagaa agtctcttcg
    13021 gcagatggac agcaactgat ctcaagattt aagtatttgg gacagatgga tatcggagaa
    13081 aaaagaaaag ctcagttagg tgcatttact tattctttag aaaaacagga agttcgtctg
    13141 cggttgtctt ctgtaggaga ttaccttcaa cgagagagtt tagtgattcg gctattatac
    13201 ggtacttttg aaacacccca tcgttgcttt agttctcgag attttgcaac tattttacag
    13261 aaaaccgtca gacgtggatt ataccttttc agcggaccag tcggatcagg caagacttct
    13321 ctaatgtatc ggttggcttt ggaagaaaaa ttgcaagtga ttactatcga agatcctgta
    13381 gagatagaag aaccgttttt tctgcagcta cagatcaatc cgaaaatagc acagacttat
    13441 gatacacttt tgaaactcgc attacggcat cgtccagact tgctaatcat tggcgagata
    13501 agagatgaat caactgcaca tgctgcggta agagcagcac taacagggca ccgggttttt
    13561 gcaaccgtac atgcacgcaa tcttgaaggt acattggtca gaatccatga actgacaaag
    13621 aaaaaagaag agctatctga atgtttagct ggtgtcattt atcaagaact tttggaagat
    13681 gccaatcacc atccttctgt tttatggagt tatcaattta tggaggaaga atcagtaaaa
    13741 aaatcatggg aggaaagtta tgaagaagct caggaaaata tttggcagtc agaactattc
    13801 taaaggatta acaagaagcc agcaaaacca gtttgcacaa accatgggag aactgctttt
    13861 atctggtttt agtctgcaag aatcccttta tttattactc acgatccgtt cgtttccacc
    13921 tgttattttg gcaaatatcc aacatcagct aaaggaaggg caagcgttta gtgaggtact
    13981 ttcgcaaata ggatatggag cagagcaact ggtacagatc gagttagctg aacgtcatgg
    14041 gaatctgccg acaactttgt tggaaattgc caaacagttt cggcttgttg aaggatttcg
    14101 caatgatttg aaaaagctgc ttgcatatcc gatgctattg ctcacctttt tgctaggtat
    14161 cttgtttagt atgcggttgt tcgttttgcc tcagcttatt ggttcaggaa tggtcatgca
    14221 agagcattgg ggtattcagc tgatacaagt ctttcattgg tatgttctac tattcatcct
    14281 agcggttact ctattggctt tactagtaag gtatcgtctg atgaagttgt ctcctgttga
    14341 tcagagtgaa tggataagca gacaattatt gattggaccg atatattcct tgtatcaatc
    14401 ggcttatttg tcactagaga ttggaaagct ttttcatgaa ggtttcgaat taaggcaaat
    14461 catagtctgc ttaaaggaaa cgaaacaaga aagtctgatt cagcatcttg cctctaagtt
    14521 gattcaagga ttggaggcag gtatgtcatt ggctgagcag ttccagaatt atcgttttct
    14581 atcagaagaa ttcagtaaaa ttgttttaca gggagaggca aagggaagtt taggtaaaga
    14641 actgattttt tacagcgaat ggacaagaaa acagcttttc aaacgtcttc atcactggat
    14701 gcattttatt cagccaatca tttttttggg cgtagcggct ttgattttat tagtttatgc
    14761 cgctgtttta ttacctgttt acggaagcat agaggaggtt ttgccatgaa aaagagaaaa
    14821 atatcttatt atagcggttt tacattgatc gaaatgctaa tcgtcttact gatcatcagt
    14881 gtattagtgt tgttgttcgt ccctaatttg tcgcgttata ggaatcatgt agaccaagaa
    14941 agtcgtgaag cgatcatcca gttggtagac acacaaaaag agctctatgc gcttcaaaat
    15001 aatggaagag ttcctactgt ggaggaattg ttgaatgaag gctatatcaa acgagaacat
    15061 gcagaaatct atcagcggcc ttgaaggtaa ggttttagca tcaggatata cgttgtttga
    15121 atcactctta ctgattttat tacttacaac gatcctttct tttccagttc tcgcattttc
    15181 tgcatggaag aatgaattgg cagtctatca atttttcggc caatttgaaa aacgaatcta
    15241 ttctacgcaa aaaatcgcta ttgtgaatca gatccaaaca ggcttttatt ggaatagtga
    15301 agagaatcaa atcatttttc atgttccgaa tccagataaa ataaattggg aagtattaga
    15361 tattcctgat gagattacct tgaaacgcca tgcttctatt acttttgctg ctagaaccgg
    15421 gaatgaaagt tcactaaaag cttatcaatt ttattgggaa gaaaaagagc ggacgattac
    15481 gtatcaattc cagataggga gtggtcgcta tacaaaaaga attgaataaa acaggatttg
    15541 ttttgttgga gtcccttaca gcgcttatga tcgcttctgt ctgtgtctac ttagtgagct
    15601 ttggccagct gtttttgctt caggcagaaa agaaaagtgg ggaggaactg ctatttattc
    15661 gaatgattta tgaagatatc aagacgcagc ggatgtatca caaaagacca gagcgaaggg
    15721 aagaaatgat cccatacgat atccaaattg tcgataataa tggagtaatc gaaaaagtgt
    15781 ttgtcaatat ggagaaagaa gcgatcagta ttgaaaaaac aagtaattcc agcatttacg
    15841 ctgattgaat gtctaattgg actgatgata ttgagcagtc tattgctcac attcaatctt
    15901 ttgattcagc aaaccatcca agtaagtgaa tttttgcagc gtaaagatca aaaagagtgg
    15961 ctaatatttt tagcacaatt agaagaagaa ctcaagagca gtcacaatgt ctctgtgaaa
    16021 aatcagcaac tgcactacac gatcgaggat aaacagtata tcatcgaaag atatcaggca
    16081 atgatacgta aaagaagaac ttccggcgga catcaaccta tgttaacaag tatcactgag
    16141 cttcaattat tggaaaaaga acacacaatt tctttttatg tacactttga aaatggagaa
    16201 gatggatatg ccatatggac aaaaaacgat cagtagaaaa tgttataagg gctctatttt
    16261 attttctgtc ttgcttttat ttcttttatg tacgttttta ttgatggcag cattagaaag
    16321 ctaccgtttg tcaatggatc ttaatatacg aatcaaaaat tattatatag caaaaataat
    16381 gaagcagatg gctttatcgg aacagtctac gcttgccgaa agttcggaag gagtttttta
    16441 ctacacaact ggatctgtaa catatcagtg ggtacaacag tccctattct tagaggtgga
    16501 agtctcaccg tttatctttc ggttcacaga agaagtaaaa aatgatacag atactagtac
    16561 agaatgatgg aatgttcgtg aaaacgccct cttttctgtt ataacactgt ttttaataaa
    16621 aaaatgtttg ccgtttcaca aataaaaaac agtgaaaacg attgaaattt tgtcaattgt
    16681 tcgatagaat taaacaggtg aaaaaattgt tataatatat ctagaaatga ggtgcaccat
    16741 gttaccagaa aaaatggaac aagggtttaa tcaaaacctg gaagctattc agcttttaca
    16801 gaatgcattg ggaacttcct ttttagaagc ctatgtcgaa aatgcagaaa atttaataga
    16861 tgattatcaa gtacgtgtgg tggatggagt gccgacaaaa gagacaacgc aacggatcac
    16921 agctctttat gaagagttga agaaactttc tttcgagcca gaagaatggc gcagactgtc
    16981 tcaattactt ttattgaagg gcagccagac agaacatttg caggcgaacc atcaactcac
    17041 tcctgatagt atcggttttt tatttgtttt tcttattgaa caactataca caaataaaaa
    17101 agcaccggtt aagattctgg atattgcggc aggaatgggc aacttgttat taacagttct
    17161 tttaaaccta tcgaatgcgg ggtaccaaac agaaggaatt ggtgtggata ttgatgatac
    17221 attgttggct gtcgcagctt ctacaagtga tttgacacaa gcaaatgttc aatactttca
    17281 tcaagacggg ttgcaggaat tattaataga tcctgtcgat tttgcaatca gcgatttgcc
    17341 aatcggttat tatccgaatg acgaaaaagc aaaagagttt ttaacaagta ccgaagaagg
    17401 ccatagttat gcacatcatt tattgctaga gcaatcaatg aaatatgtga agccggatgg
    17461 ttttggtttg tttttgatgc cgagtggatt tttagaaacg gatcaaagtg aagaaatcaa
    17521 aaaatggttt aaagaagaag gttatcttca aggaatgatt caattgccag atgaattgtt
    17581 ccgtaataaa caatcgcaaa aaagtatttt gatcttacag aaaaaaggac cacaagcaca
    17641 acaagtaaaa gaagtcttgc ttgtgaaact tgcttcatta aaagaaccag agaaggtgac
    17701 ggaatttttc aacgagttta aaaactggaa atcatctgct ctgtaatcat tcaacgagaa
    17761 ggagagtcat atgtctaaaa caattgcaat caatgctggg agttcaagtt tgaaatggca
    17821 attatatcaa atgccagaag aaaccgtagt tgcgaaaggg atcgtcgaac gtatcggttt
    17881 acaagattct atttttacca tcaagtacgg cgataatcaa aaattcgaac aaatcatgga
    17941 tatcgaaaac cacgaagtag cagtaaaaat gctgttagat cagttgattg aactgcaaat
    18001 tttaagctct tatgatgaaa tcaccggagt agggcaccgt gttgttcacg gaggagaaac
    18061 ttatggggat tcagtagtga tcgatgagaa agtaatggac cgcattgctg aattagcaga
    18121 atttgctcct ttgcataatc ctgcaaactt aatggggatc aaagcgttta aaaagatttt
    18181 acctgacatt ttgagtgtgg ctgtattcga tacatctttc cactcaacaa tgccaaagca
    18241 aaattattta tatagcttac cggtgtctta ttatgaagat ttcaaagtaa gaaaatatgg
    18301 cttccatggc acaagtcatc gttatgtgtc ggaacgtgcg gcaaaattat tgaacaaacc
    18361 gatcgaagaa ctaaaaatca tcacttgcca cttaggaaat ggtgtatcga tcacagcagt
    18421 cgatggaggt aaatccatgg atacttctat gggattcaca ccattagctg gggtgacaat
    18481 gggtacacgt tcaggtgata tcgatccagc tgttctccca tatttaatgg aaaaattaga
    18541 gattgatatt gatgaaatga tcaatgtttt gaacaagaaa tctggtctgc taggcctaac
    18601 aggattgtct agtgatatgc gtgatcttga aaagaactat gaaaaagaac atattcgttt
    18661 agcttatgac attttcgtgg accgcatccg aaaatacatc ggcggttatg tgacaacgat
    18721 gaatggtgtt gatgcaattg tctttactgc tggtatcggc gagaatgacg gacatgtacg
    18781 tagtgaaatc atcaaaggta tgtcttggtt tggttgtgaa atcgatccag cgttgaatga
    18841 attgcgtggt gaagaagtag atatctctac aaaagaatca aaagtaagag tattagtgat
    18901 cccaacagat gaggaactaa tgattgcccg tgatgtggag cgtctgcgcg gctaagccaa
    18961 agcattcgtt aggataaaag atgaaacgca tgcaagaggg aattcttgca tgtgtttttt
    19021 ttgcggagaa gaccgcaaaa tggtaattta acttcaattt cccttctttt ttacaggatc
    19081 ttcttaggga attttgcttg gaaaagtggt caaaagggaa aagactggca ttttatttat
    19141 tgattttcag gaaaatccca atattttatt ttcattcatc tttataaggg acattacata
    19201 tgtaaaaaga aaaaacattt ttagatcagc ctcgtgggct gtcgacttta ttcttcgctt
    19261 tatgtttagc tagaaaaccg atccgaaaca ttcattgatc gaataataaa aacttgattt
    19321 tccacctgta ctttgcctga atcgtgaaag cacaggtatg aaaatcaagt tttttgttgc
    19381 gaaaaaacgt cctagtcaat cagttggccg agcggctggc ggctgatctg ctcctgatca
    19441 ataacgagtg cttcttggaa gtgttgctgc aaaaagtagc ggtcatggct gactgctagg
    19501 agcgttcctt gatagtcttg cagcatttct tcaatttctt ctcgagcata gctgtcgagg
    19561 tgattggttg gttcatccaa aatcaggacg ttgatttttt ctaaaaagag tttcagcaac
    19621 gccaaacgga ttttttcacc accggataaa tctttgatcc gtttacccac atcgctttga
    19681 taaaagccac ttttggctaa ttgccgtcga gcgacttctt cgtttccagt caatgtgatg
    19741 gcgtaagcca gcaaacggct atcgggatcg gcaaactgca gctgctgcgg caaataaccg
    19801 atttgcaagc tactacctaa tttgatggtg ccaccgtaag gcttttcctc accgagtaat
    19861 aatttgagta aggttgattt tcctgcacca ttgtcgccga tgatggctaa atgatctcca
    19921 cgatagactg caaaactgct gtctttgaat agtacttgat cagcgtactg ctggtgcaag
    19981 ttttgaatga tgaaaacttc tttgccagat tttccaccat tagacaagct ttgcagccga
    20041 tttttcgggg gaggtggcgg tttgacgagt gtcagtttcg ccaggcggcg ttccagttct
    20101 ttggcttttt tgaagaagga ctcattgtct ccttcatgtg cccactgacg aaaacgacga
    20161 atcatgactt tcaaccgctg gacttctttt tgctgcagtt cgtaattttt tgtcagctca
    20221 gccaagcgag cttctttcaa gactcgaaaa cggctgtagt ttccgggata ctcaatcaat
    20281 gcaccttctt ccagttccca tgtttttgtg gtgacttgat cgagaaattg ccgatcatga
    20341 gaaacgacca gaaccgattt ttttgtattc tgtaaatagt tttccaacca gcgaatactg
    20401 ttaagatcta aatgattggt cggttcatcg agtaaaagta aatcggcatc ggctgctaaa
    20461 attttggcta aagcgacttt aactcgttcg cctccgctaa gttctgttaa ccgtgcttcc
    20521 tgacggtgtg gaatccctaa gccttgcaag atcgctgcaa tccggtcttc taatacgtaa
    20581 ccgcctagtt cttcaaagcg atgctgcagc tcaccgtaac gggccagaca cttctctaag
    20641 tttgtatctg gttctgtcat caatgcttcg tagcgactca tttgctgttt gaggtcctgt
    20701 atctcagcgg cagaatggag caagtagtgg ttgacggtcg cttcggaaac tgtaagttct
    20761 tgttcgaccg tcccgatctt taagcctttt ttgcgactga taacaccgct gtcgacacct
    20821 tctctgccgg tcaagatttg taaaaaggtt gatttgccag ttccgttgat accgactaag
    20881 gcaatttttt caccagcttc aatttgacag gataaatcct caaataatgg attcccgccg
    20941 attgtttttt taatagaaat tgcttgtatg atcatgatct ctctccttga gaccactcaa
    21001 aaaggccatg gttatccctg gcctgtgtta tttaaactca gattatcatg agaaaaatac
    21061 cttgagatgg ccattgattt tacgtgaatt caactgtttt ggacaaactt gtcccgtcaa
    21121 cagcaactgt aaaaccaatt gcatggctaa atgcgatatg gtatcgttgg taattttcat
    21181 tacttgttat tttagtcatg cgcatcatag tattttccct ccttcgtgta gttgtctttt
    21241 ccagtgtacc tgaaagtgtc agaaagttca actagcgctg acatttactt aatatttatc
    21301 gatgtgtaat tctgtcagag agcttttttt atctgactga gggtaatgtc tcgtggacca
    21361 catcattgta ttctgagcta aaccagcgtt caggcgaaat catatggtgt ttgataaaaa
    21421 actttgtcta catgacttcc ttttgccatt tgcttaatac cgttgcatta aacagctctt
    21481 ctctttggaa atctcaccaa catcgcgttc aggagtatcg ttgtggttgc aatggcaagc
    21541 ggtagccttt catcaattct tgaatgattt accgaatgta gcacttgcct tctcgcggta
    21601 cccgaacccg aaataaaatt ttagtttggc gataaaatcg gtatccgcca tcgatacttc
    21661 atattttttc gtatcagatt catcggaaac ttccacattg acgaaccaat aagctttggc
    21721 atgcttaggt cgttttaaac cacaccaggg cgactaatcg ccctggtgtt cacttttttt
    21781 attttacttg aactcattga ctgttttccc tttattttaa acattataaa gaccgatgag
    21841 tgcttgccgc gtcttttgtt tttatcacgg ttttttgtgc aaaaaaacct gccgatagtt
    21901 ggcaggtcgt ctacgtgtta agctttggtg tggtctttag ctggcaattg gttttctaaa
    21961 tcagttcgga caacaagcac atcgcaagct gcgtttctaa taacatattc agaaacagaa
    22021 ccaataaata aacgttctac agcattcaat cctgtggctc ctaacataat caaatctact
    22081 tgattatctt ctgggatttc tctggcaata atttgttttg gtgagccata ttctacgaca
    22141 gaggttacat tattcaagcc agctttcttc gcattgcttt cataatctgc caatgtttgc
    22201 tttgccattt cagtagcttg ttctgcaagc attccatcaa aggatgaaac ggtttggaaa
    22261 gaacgtgtgt caatgacatg tgctaataga agttctccgt tatttcggat agctacattg
    22321 accgcctttt taaaagctaa ttcagcttca tcagaaccat ctacggcaac catgattttt
    22381 ttgtattgtt gtaacataag cattcactcc tcaagtcaat cgtattgtac tcttttattg
    22441 tagaacactt tagggaaaaa gagaattatt tactgctttg gttcagcaat tttttttgca
    22501 aatcggatac tgaaggtggc agaaacaata attacgatca gtaaaaagac caaggcaata
    22561 aagcgttgat tgaaaaaagc tgttaaaata cccattacgc ctaaaacagc atatgcagca
    22621 ccgtaaaatt gtaggaatcc ttgattttta tcatttttgt tgatcaatac aaaaaagata
    22681 tcctgtttat taaataaata atagctaacg aataataata ctaaagtggc gataatcatt
    22741 aaaatcctaa tcatgaacaa atcctccaaa ataagcaaca aatagaaaaa gcaatttgcc
    22801 aagagcaaat tgctttattc tttaaaagat ggtaatctcc gttaatgccg ttgtttgtcc
    22861 tgtagtattg atcccgcgaa ttcaagcagg tgggtcccat ggtcgtagct tcgaactacc
    22921 aaatgataag gcatgttacc agcagtgaca caagacgggt cccaagatat caataaaaat
    22981 gttcggtcaa cacacaaaga ggacaattcg aacatcacag atttcccacc tctatagtag
    23041 catatgaatt taaaaagagc aatgagagag ctcgcagaaa cagaaccgtt ttcttgtcta
    23101 gttttttgga ggatgctttt tccactcttt tatacggtaa tactgttgac ccagagcctg
    23161 ttcatatttc cctgtatctt ttggctgata atactgagca ttcttcagtt tatctggtaa
    23221 atattgctga ttgacccaag cctgatcaaa atgatgagga tactgataac ccacgccacg
    23281 gttgagtgat ttcgcacctt tgtaatggct atctctcaaa tgatcaggaa catctccagc
    23341 tttgccctct cgaatatcag caagtgctgc atctaatgcc atgtaggcag aattggattt
    23401 tggcgacaag caaagatcga cgacgacgtc tgctagtggg atacgtgcct caggcaatcc
    23461 caatttttca gcagctaata cagcgttcac tgtacgagcc gcagcagcag gattacctaa
    23521 acctatatct tcataaccga taaccatcag acgccggcaa atacttgcca gatcacctgc
    23581 ctcaactaaa cgggcgagat aatgaagtgc agcatccaca tcacttccac gaatcgattt
    23641 ttgaaaagcc gaaataacgt cataatgagc atctccattt ttgtcatggg taagagcttt
    23701 tctttggaca cattcttcaa tgatcgacag tgtaagatga atccttcctt ctttatctga
    23761 aggagtcgat agtgtagcca gttccagccc attcaatgca ctccgcaaat cgccgttcgt
    23821 tgcacgcgaa aggtgaagaa gagcatcttc gtctaactgg attgcttgtt gtccaaggcc
    23881 gcgttcttta tcccttaaag catgttcgac tgccaactgg atgtcttgtt ctgttaatgg
    23941 tttgacttca aagatctgtg tacggctgcg gatcgctgga ttgatggtaa tataaggatt
    24001 ctcagtagtc gctccgatca agatgattcg gccactttct aaatgaggaa gcagaaaatc
    24061 ctgttttgtt ttatctaatc ggtgtacttc atccaataag aggatcactg taccactcat
    24121 ttttgcttct tccgctacaa cttgtagatc cttttttgaa tctgtagcgg cgtttagcat
    24181 gcgaaatgca taattagtag agccggcgat cgcacttgcg atactcgttt ttccagtacc
    24241 aggaggtcca tatagaatca tggaagagag catgcgagca tcgaccatgc ggcgtatgat
    24301 ttttccttcc ccgactagat gctgctgacc aacgacttca tcgatcgttc gaggtctcat
    24361 gcgataagcc aatggctgtt gcataggatt ttcctccttc ttgtttttac gtcccttaat
    24421 tatatcatat ttagcaagat gcctagaaag aacagccttc tgttgttttg ttttcatagc
    24481 ttatccaact aatattgtgt atgataaagt aggtgagaaa aatgacggat aaacaaaaga
    24541 tagatgaatt tttttggaat aaaacgacgc cagaagtggc acgggattta ttggggatgt
    24601 atttggagca tgacacacca gaaggaagat tagctggata tattgtagac gcggaagcat
    24661 acctaggtcc agaagacgag gccgcccata gctatggttt aagaagaaca ccgcgtgtgc
    24721 gggcaatgta tgaaaaacca ggtacgatct acctttacac gatgcatact catcggattt
    24781 tgaacatcat tactcagcca gaagggattc ctcaaggagt aatgatacgt gcaatcgaac
    24841 ccgccgcaat gattgatcaa atgagtaaaa atcgtggcgg aaaaactggt ccagatatca
    24901 gcaacggtcc gggaaaatta gtggaagcat tagcaattcc tcaagaactt tatggtcagt
    24961 ctatagcaga tagttcgtta cgcttagttt ttgagaaaaa aaagacacca aaaaagatca
    25021 atgctttgcc tagaatcggt atcccaaaca aaggtgtatg gacagaaaag ccgttgcgtt
    25081 ttgttgtgtc gggaaatcct tatatctctt tacaaagaaa aaaccaaatc gagaaagatt
    25141 ggggttggag gaaagaaaat gaaaaagaag gatctattaa catatttaga tgaaataatt
    25201 gaaaaacaag tgacagacta tgatgtagct ttagattggg atacaaaaaa tcatacgatc
    25261 gagatcgttg ttcgcttgtt tgcagaaaat aaagcacaat ttgagattga tgatgcagaa
    25321 gggatcgttt cgcaagaacc aattatcgaa tttgaagacg gcgtacttct ttttaatcct
    25381 cagaaatctg tttttgatga acgcaattat ctagcagtaa tcccttatga aggaaaaaaa
    25441 gggttggcaa aatcagtagc tgattcttta gtggaatatc taaatgaagt attagctcaa
    25501 gggcaaagcg atttgcttga ttttttggat gaagacgatg acgaagctgt attcgagctt
    25561 cactgggata atcaacaact agcagaatta gtagaagtaa aacagcaaaa tgaagcagat
    25621 acttatttac cgtacccaag ttattaagga gtgacagata tgaaatggaa tgaagtaaaa
    25681 gtagaaactg aaagtgaagc agtcgaagca gttgctaata ttttgatgga ggcaggggcg
    25741 agtggtgtcg cgattgaaga ttctttagat gttgaacatt ttcagtcgga tcaatatggt
    25801 gagattttag ataaaaatga ttttacatcg ctgaaagaag gcgcactagt catggcttat
    25861 tttccggaaa cgactttctt accggaaatc ttgcctttta tcaaagatcg tatcacacaa
    25921 ttacctgagt ttggtctagc tattggaaaa aataaagtaa cagttagtga agtagaggaa
    25981 agcaactggg caacagcctg gaagaaatac tatcatccgg tgcgtattac gcgaatgctg
    26041 acggttgcgc caagctggga aaactaccag acagaagatc ctctagaaaa aattatcaca
    26101 ctagatcctg gtatggcatt tggcacaggc actcatccca cgacttcctt gacattgaca
    26161 gcactagaaa cagtcttgcg tggtggtgaa acattgctag atgtgggaac tgggtcgggc
    26221 gtgctaagta ttgcagcaaa atatcttggt gcaaaagatg tctatgcctt tgatttagac
    26281 gaagtagccg ttcgttcggc gaaagaaaat atggatatga atgaaatagc caaagatgtc
    26341 catgtatcag ctaacgatct tttgacagga atcgagattg aaagtgatgt aatcgttgcg
    26401 aacattttag cagatatcat cttattgatg atcccagatg cttggcgttt actgaagcaa
    26461 acaggcacgc tgatcgtttc aggaatcatt gaagagaaga agcaaatggt tctggatgcc
    26521 atgttagaac aagggtttat cgtggatcaa attttccagc aaaaagactg gtatgcaatt
    26581 attttgaaaa aaccagaggt ggaatagatg cagcggtatt ttttaaaaga atcatatgaa
    26641 tcaaaagact attttgtttt agaaggggaa aactatcacc acattgtacg ggttatgagg
    26701 atggaacccg aggatgaagt ttttttggca ttcaatgatc aaatagccat tgttgcagaa
    26761 atcacggaga ttactgaaga ggctgtttat ctgaaagaaa ttaaaaaaga agaaaatcaa
    26821 aaggaactgc caagttcgat taccatagcg agtggctatc ctaaagggga aaagctggat
    26881 tggatcgttc agaaatccac tgaattagga gcgcaagctt ttcttggttt cccggcatca
    26941 gcctctgtcg ttaaatggga tgcaaaaaaa cgtatgaaac gacaacaacg gcttgaaaag
    27001 attgctcaag aggcagcgga acaatcccat cggcagatcg tgccatcagt agagttattg
    27061 gaaacgaaac aagatttatt tgagcggcta gatgattatg acgtggtctt ggttgcttat
    27121 gaggaatcag caaagcaagg cgaaaaatca aatgcagcca aaattcttag tgaaacaaaa
    27181 ccagatagtc gaatcttagc tgtctttgga ccagaaggtg gattatcccg cgatgaagtc
    27241 gattattttg tagaacacaa agggatactt tgtggattag gaccaagaat ccttcgtaca
    27301 gaaacagcac ctctttattt attaagtgct gctagctatc aatgggaatt aatgaatcct
    27361 tctttcagct aacgttcttc attaataaaa gagtatcgac agaaagaatt gaaaaaatag
    27421 tcaacaattt gtataataga aacaattatt tatacaatgg atacgaaaaa tcgtttgaaa
    27481 aagcttttaa aaagcgaaca tttccgtaaa aaaacgtata actgcacgga ttttgggaca
    27541 attatcaaac agatatttgt cccgattccc gttttaccga aaaaagaaag ggggatcgat
    27601 tcctgtgaca aaagaagaaa ttttaacggg acccggtgtc ataaagctcg ttagtcaata
    27661 catgggtccc gaacatgtag catttgttga gaaagcatgc gaatacgcga ctgctgcaca
    27721 tgacggacag tttagaaaat caggcgaacc ctacattatt catcctatcc aagtcgcagg
    27781 tatattagca gatttaaaaa tggatcccca tacagtggct acaggcttct tacatgatgt
    27841 tgttgaagat acagaaatca ctttagaaga tctgagagaa gaatttggcg atgacgttgc
    27901 tatgttagtg gacggcgtaa ccaaattagg gaaaataaaa tataaatccc acgaagagca
    27961 gctagcagaa aaccaccgaa agatgctgct agcaatggct caagatttac gagttatcat
    28021 ggtcaaatta gctgatagac tacataacat gcgtacgttg aagcacctgc gagaagataa
    28081 gcaaagaagg atcgctcagg aaactttaga aatctatgcg cctcttgcac atcgtctagg
    28141 gatcagccgg atcaaatggg aattagaaga tacagcactt cgttatctaa atccaaaaca
    28201 gtattaccgt atcgtccact tgatgcagac gaagagagaa gaacgtgaaa aatacgtaag
    28261 tggtactgtt gaagatattc gaatagcgac agaagagctg gggatttttg cagaaatcta
    28321 tggacggcca aaacacattt attcaatcta tcgtaaaatg aaagatcaga aaaagcagtt
    28381 caacgaaatt tatgacttgc tagctattcg agtgatcgta gattcaatca aggattgtta
    28441 tgctgtatta ggagcaatcc acacaaaatg gaaaccaatg cccggcagat ttaaggatta
    28501 tattgccatg ccaaaagcta atatgtacca atctttgcat actaccgtga tcggtccggc
    28561 aggaaatccg gtagaaattc aaatccgaac acaggaaatg catgaaatcg ctgaattcgg
    28621 ggttgctgca cactgggcct ataaagaagg aaaaaatgaa aaagtagaac cagatggtat
    28681 gacgaaacaa ttaagctggt tccatgagat actcgaactt caagacgaaa gctatgatgc
    28741 ttctgaattt atggaaggcg taaaaggaga tatctttagt gataaagtct acgtcttcac
    28801 accaaaagga gacgttactg agttaccaaa aggatccgga ccattggact ttgcatacag
    28861 tatccataca gatatcggta acaaaaccac tggtgcaaaa gtaaatggca aaatggtgca
    28921 gcttgattac aaattgaaaa acggagatat cattgagatc atgacttctc caaattcatt
    28981 tggcccaagt cgcgactggt tgaaattagt tgctactagc aaagcaagaa ataagatcaa
    29041 acgtttcttc aaagcccaag atcgagaaga aaatgtgatc aaaggccacg aatccgtggt
    29101 caaatgtatt acagatctag gatttacgcc taaagatatt ttgacgaaga acaaactgca
    29161 agaagcactc gatcgtttta attatcaaac agaagatgat ctctatgcag ctgtagggta
    29221 tggagaagtt agccccttga cgatggccaa tcgtctgact gaaaaagaac gtaaagaaca
    29281 aaaaatcgag cagcaaaagc aagaagcaga agaaatcatg aatcagccga aaaaagaacc
    29341 tgacaaaatg aaagtacgtc atgaaggtgg cgttgtcatt caaggggtag aaaacttact
    29401 aattcgtatc agtcgctgct gtaatccgat tcctggtgat gatatcgttg gttatatcac
    29461 taaaggcaga gggatatcca ttcatcgtcg agattgtccg aatgttcagc ctgacaaacc
    29521 aaatgtagca gaacgtttga ttgaagtcga atgggaagat acatcgaata cacgaaaaga
    29581 gtatgatgca gatttggaaa tttacggcta taatcgttca ggcttattga atgatgtact
    29641 tcaaacagtc aatgcgctaa cgaaaaatct caacagcgtt gaagcacgga cgaataaaga
    29701 taaaatggcg acgatccatt tgacggttgg tatccagaat ttatcccacc taaagagtat
    29761 cgtggataaa atcaaagcag tacctgatgt ctacagtgta cgccggacga atggatagga
    29821 ggacagatat gagagcagtt gttcaacggg taagtaaagc tgctgtgtca gtcgatcagc
    29881 aagaaattgg aaaaattggc tacggcctac ttgttttatt aggcattcat gaaaccgata
    29941 cgcaaaaaga tgtggactat ctggtaaaaa aaattgcaca aatgcgtatt tttgaagatg
    30001 aacaaggaaa aatgaatatt agtgtagaag atgtgggagg acaaatttta agtatctctc
    30061 aattcacact gtttgcggat acgaaaaaag gaaatcgacc aagctttgtg gaagccgcac
    30121 gaccagaaac agctattcct ttatacgaat cattcaatga aggaatcaga agtcgcggca
    30181 tcacagtcgc taccggacaa ttcggagcag atatgtcggt ttctctcgtc aatgatggac
    30241 ctgtaacgat cattattgat tctaaaaaca aataaagtaa tctggttttc actagtaaaa
    30301 actatgaaac acgtcgctta agttagactg ataaactcta acttaagtgg cttttttgtc
    30361 tgcaaaaagc gcttcttttg tcagcagtcg gaaaaaaagt taagcttaaa ttatacaagt
    30421 tattttttat aggaggttgc tgaagatgaa agaagtacca gtagtagata tcaaaatcac
    30481 agatttaaaa aaattgtatc aaaaaggata caacatgttg gaggagttac gccatgaagc
    30541 ggacgctccc gtcgtcaaag caaagatttt caataaagaa gctatcacga tctacggatc
    30601 atcagcagca aaagtatttt atgatccaag gaatttcaaa cgaaaaggtg ctatgccaaa
    30661 attagtattg aagacacttt ttggtcaagg tggagtacag actttggatg gagctgctca
    30721 tcaccatcgg aaaaatattt ttatggatct aatgacaccg gaaagaatgg aagattatca
    30781 tcgtatctta gataagaatc tgacacaagc acttgaagca cagcatggtc aatttgaact
    30841 atttgattta agtaagatgg ttttctttac atctatttgc gagtgggcag gtatcaattt
    30901 atcagcgatt tctaaagatg aggtcgaaaa attagcagaa tatcaaatct ctatgatcag
    30961 cggaacgttt acttctccga ttgatcacat aaaaggtgtc gagaatcgca aaaaatcaga
    31021 aaaatgggcg caaggcttga ttgaagaagc tcgacaaaat cctgtggctg gaaaagaaaa
    31081 tgtggcatta tatgcttttg ccaatgccac agatttagat ggtcagcttt tacctctgga
    31141 agtggcagct gttgaattat tgaacatcat ccgtccaacg gttgctctaa ctgtgtgggc
    31201 ggcattgatg ggacatgcac ttttcagtag accagatttg tatcagcaat taaaaaatga
    31261 cttttcgacg ttacaagatc cgtttattca agaaatgaga cgctattatc ctttcttccc
    31321 aatgctacct gcgatttcgc tgaaagaagt agaagtagat ggttatcgta taccagaagg
    31381 cagttgggtt attttagatt tatatggaac agaccatgat gaacgaacag ttgaagcgcc
    31441 agattccttt atgatcaaac ggtatgtagg gaaagcaaaa gatatttcct ataaagaaga
    31501 atatgagatg attgcacaag gcgggggaaa ttttcgacaa atgcatcgct gtgcaggaga
    31561 atggatcact cttcatagtc tacgtgtgtt ttccgatcag ctagtaaata agtttgagtt
    31621 ctctgtacct gaacaagatt ggacgattcc attcaatcag tttccgactt atccgaatag
    31681 ccgagcgcta ctttacaaga attagattag cataaactta tcgaaaaaaa ggaagatcaa
    31741 acagtgctga tcttcctttt ttcatattac tataaattga taaggtcaat tgatcaaaat
    31801 ccacgaaatg cttcatcaat ggtttgataa tcttcattgg ataaatgcaa atctaaagct
    31861 tggacattgt cagatacttg ctctggacgc ttagctccag gtataactac agacactcgt
    31921 ggattcttca tgtaccaagc taaaacaagt tgcgcaggag tggcttggta tcttttagca
    31981 atggggcgaa gtacatcgac agcggttaaa atttctctga aacgttctcc ttggaaatct
    32041 ggatttcttt ttcgaggatc tccttcacca aattgttttt cctcaccaag ttcatatttt
    32101 cctgtcagca aaccggaagc aagaggaaaa tagggaacaa aactgatttt gtttttttca
    32161 agataaggga ataattcttt ttcagcctgc cgatggatca aactgtattt atcttctact
    32221 acatcgacat atccatctgc attcgcttct ttcaattgtt ctaacgtgaa gtttgacaca
    32281 ccgactgctc ggatttttcc tgcttctttt aattcgtgca atgtagcaac tgattcattt
    32341 tttggtgtgc tttcatccgg aaagtggata taaaaaatgt cgatgtaatc agtttgcaga
    32401 cgttttagtg catcttccac cgattgtttg agaaactcag gagaattatc aaatgttcgc
    32461 cctttatttg gtacatgagc agcttttgta gcgatgacga cacgtgagcg atcatattct
    32521 ttttccttca gtacctcgcc aatcagttct tcggaacggc cgtttccgta agcataagcg
    32581 gtatcgatca aattgatccc gctattcaaa gctgtacgaa ctacttgttt tcctgtctca
    32641 tcttccaaac cgtcaaaaag attatgtcct ccaacggcat ttgctcctaa tccaagctgt
    32701 tctgcgtaga cttgtgaatg tccgattctt atttctgcca tagctgattc ctcctttttg
    32761 tctagtctaa aacaaaatac caaaaagctg aactaaaacg tttttgtgag gggaaatagt
    32821 cagatatctc ttgactttga gactggtttt tagtaggtta taagtaatat cgaatgtcaa
    32881 tgaaagagcg agtaagtttt tgaaacttta caagagagga tcatcgaggc tgaaaatgat
    32941 ctaaagtttc attagcctaa agacactctg gagatggacg agtgaaaagc cgtcccgcgt
    33001 acgagcgtta ttcgtaagag gaaagagaaa tctttcaaaa ttaggtggta ccgtgtatga
    33061 atttcattca cccttgttca tgatgaacaa gggtgatttt tttatttaca tagctaagaa
    33121 agggagagaa aactatgagt ttccaaagac caaaaggaac aaatgatatt ttgccaggcg
    33181 aatcagaaaa atggcagttt gtcgaagaaa cagcacgttt attattcaga gattatcagt
    33241 ataatgaaat gcgtacaccg atttttgaac actatgaagt gatatcccga agtgtagggg
    33301 atacaacgga tatcgtttca aaagagatgt atgattttta tgacaaaggg gaacgccatg
    33361 tgacgcttcg accagaaggt acagcaccaa tcgttcgttc ttttgttgag cataaattgt
    33421 tcggcccaga gtatgcgaaa ccgttcaaaa ctttttatat gggaccaatg tttcgctacg
    33481 aacgccctca aaaaggacgg ttacgtcaat tccatcaaat cggagtagaa gcatttggat
    33541 cagaaaaccc tgcaactgat gtggagagca tggtgatggc acttgatttc ttcaaacagt
    33601 tggggatcac gcaaatccgg ctagtcatca attcattagg tgataaagaa acgcgtcaag
    33661 cctatcgtca agcattgatc gactatcttt taccttttga atcagagctg agtgaagact
    33721 ctaaacgccg ccttcatgaa aatccattac gcgtattgga cagtaaagac aaacgagatc
    33781 aaaaatttgt ggcagaagct ccatctatct tagattatct aagcgagcct gctcaaaaac
    33841 attttgatac cgttgtttcc atgctggatg cattggctgt tccttatgaa atcgacagta
    33901 atatggttcg cggactagat tattacacac atacgatttt tgaaatcatg agtgacgcac
    33961 caaaaatggg ggcacaagca acgatttgcg caggcggacg ttatgacaat ctagtggaag
    34021 aactaggtgg tccttcaaca cctggcttcg gatttgcaat gggtatcgag cgattactct
    34081 tgactatgga ggcagaggaa gtagttatcc ctgcatttaa tgagttggat gcttacgtgg
    34141 tcgcactcgg agacgaaaca aatatcgaag cattgaaagt ggtccaagcg attcgaaact
    34201 ttggtttttc agctgaccgc gacttcatga accgtaaagc aaaagcgcaa tttaagacag
    34261 cagataaagc gaatgccaaa ttagtattgg tgatcggtga agatgagctt gctagtcaaa
    34321 cgattaatgt caaagcaatg gcaagccgaa aagaaaaaag ttttccatta gaagagatat
    34381 atgaacattt tgatgaagtc tatgatgaaa tgactttatt cgagtaggag gaaaaaaata
    34441 aatggcacaa agaacgatct attgcggatt agtttccgaa caacaattag aacaaacagt
    34501 tacattaaaa ggatgggtac aaaaaagacg agaccttggg ggagtaatct ttatcgacct
    34561 acgtgatcgt gaaggaatcg ttcaaatcgt ctttaatcct gaaatcaaca aagaagcatg
    34621 ggaaatcgcg gataaatgtc gcagtgaata cgtgatcgaa gtgactgggg aagttagaag
    34681 acgcggagaa aatgcagtaa atcctaaaat ggccactggt gaattcgaag tgattgcaag
    34741 tgaaatcgtg attttgaatc aagcaaaaac cccgccattt caaattgaag atgatcaagc
    34801 aatcagtgac gaaatacgtt tgaaatatcg ttatttggat ctgcgtcgtc caaaaatgac
    34861 taaaaacatc aaattaagaa atgcgacaac aaaagcgatt cgtcattatt tagatgataa
    34921 tgactttctc gatatcgaaa caccttacct agggaaatct acaccagaag gcgcaagaga
    34981 ctacctagtt ccttcacgtg tccatgctgg acatttctat gcgttgccgc aatctcctca
    35041 attgtttaaa caattgctga tgaatgctgg attcgaccgt tattatcaaa tcgttcgttg
    35101 tttccgcgat gaagatttac gtggagaccg tcagcctgaa tttacgcaag tagatattga
    35161 aacaacgttc ttaacagcag aagaaatcca aacttacaca gagggattga ttgcgaaggt
    35221 aatgaaagaa gttcgcggta tcgaagtcac attgccattt cctcgtatga cctatgatga
    35281 agcaatggct cgctacggca gcgacaaacc ggatacacgt tttgatatgg aattgatcga
    35341 tctaagcgat acagtcaaag aagtagaatt caaagtcttc caaatggctc ttgaaaacgg
    35401 cggtgtcgtg aaagcattga atgctaaagg cgctgcagat cgctactcac gaaaagacat
    35461 ggatcagtta ggtcaatatg taggacaatt cggagctaag gggcttgcat ggctgaaagt
    35521 agaagaagac ggattgaaag gtccaattgc taaattcatg ggagaagcaa cagaagcaat
    35581 cattaaagca acagatgcaa aaccaggtga cttgctgatg tttggcgcag ataaaagtga
    35641 aatcgtcgct gctgcattag gtgctatccg gacacgttta ggaaaagaat taggactaat
    35701 tgatgaatcg aaattcaatt tcttatgggt aactgattgg ccacaatttg aattttcaga
    35761 agaagaaggt cgatatgtct ctgctcacca tccattcacg atgccaaaag aagaagatat
    35821 cccgttattg gctgaagacc ctgcaaaagt ctatgcagaa gcttatgata tcgtcttgaa
    35881 cggttatgaa ttaggcggag gttctatccg tattcatact cgtgagcttc aagaaaaagt
    35941 actagaaact ctaggcttta caaaagaaca aatggaagaa caatttggtt tcttgttaac
    36001 agctttagat tacggattcc ctccacatgg cggtattgca ttaggattgg accgttttgc
    36061 aatgttatta gccggagaag ataatattcg tgaagtcatt gcctttccta aaaacggaaa
    36121 agcagcagat gtgatgagtg atgcaccaag tatggtttcg cctttacaat tgttcgaatt
    36181 gaatattgat gtaacgaata tagaagaata gccgataaaa aggtaaaaag gatttgtcga
    36241 atacgcttct tttgacaacc ttgatttaat tgaaaaacac tttataatga agccataaca
    36301 tataaagcgg ggcttttcca tgaaaaaaac attcgaaaat tgggcttatc atgattacac
    36361 gaccaagctt tcggtatcta tcgtttatgc gttgatcgca tcagtcgcat tgaatttctt
    36421 ttatcagcca ggacatattt attcaagtgg tattactggt ctagctcaga ttttgacgac
    36481 tttgtcaaaa tcactgatag gattcgaagt accggtatca acaactttgt atttactgaa
    36541 tatacctttg tttgtattgg cgtggttaaa aatcgggaag aagtttacaa ttttcacttt
    36601 tatcacagtc actttgacct ccctttgtat ccatatttta ccggaaacag tcctatctac
    36661 cgatccaatc atctgtgcgt tgtttggggg ggctgtgatg ggactaggta ttgggctagc
    36721 gttgagaaac ggcctatcat cgggcggtct agatatcgtg agtatcacga ttcgtaaaaa
    36781 aacaggaaag tcgattggtt ctatttcgat ctacttcaat gcattgatcg tttttgttgc
    36841 cggaattcta tttggctggc aatatatgtt ttacagtacg ttgtctattt tcgtcagtgg
    36901 aaaagtaact gatgtcgttt atactaaaca aaagaagatg caggtaatga tcgtaacgaa
    36961 acatccagaa aaagtagtaa atgaaatcca aaactgtatg cgtagaggga tcacgatcat
    37021 caatgaagca gaaggtgctt ataagcatga taagcagaca gtattgatga cgatcgttac
    37081 acgatacgaa ctgcctctac ttagagaagc aatgaaagct tctgatccac aagcttttgt
    37141 aagtattgca gaaaacgtcc agatacttgg tcgtttctat gaggatggca tttagatcga
    37201 gtttgacaaa aattcatgaa atactgctgt agacagacgt tcgtttgtct gcagtttttt
    37261 tctaccatag tagaatcagc aaagaaaaac tgctttttta tttgaaattt tcttaaagtt
    37321 gaaaaaaagc atgtttattt ttttaaattt atgggatgat agaaaaaaat agtagagaaa
    37381 ggacacgatt ctacttgcta ttttcactta atacccgtat attacgaatg aaaaaagttt
    37441 atgaaaagtt ggaatattga atggaaaaac aaaaaaggtt aaaaaacagc cgctacatca
    37501 ctgggtttga tgggctccgt tcattagctg tggtgggtgt tatcttctat caccttctgc
    37561 caactagtat gaaaggcggc tatttgggcg ttccgatttt tttcgtcgta tctggttatt
    37621 tgatcacgga tctgctgcgg caggaatggg aacaaaatgg aaaaatcaat atttggcaat
    37681 tttatgtcag aagaatgaag agactctatc cggcacttgt ttttatgctt gtgacagctt
    37741 cggcttatat cactttgttt cagcgagggc tgttaaacaa tcttcgagga gttgtggtca
    37801 gcagcttact gtatgtcaac aactggtggc aaatcagtaa cggtttatct tatttcgatc
    37861 gatttgctaa tgagtcaccg tttacgcata tctggtcttt agcagtagaa ggtcaaaact
    37921 atttggtttg gccgatcttg tttgtattgt tgatggtatt tgttcgtaaa agaaaatgga
    37981 tcttttatac tgtgttaggt acatccttcc tctccgccat cttgatgatg atcttgtata
    38041 caccaggagg cgatccaacc cgtgtttatt acggtaccga cactcgtctg ttttctatat
    38101 ggttgggaag tgcgcttgcg tttgtttggc caagtacgcg tttaaagaaa aacatcccga
    38161 aacaagcgaa aaatattctg aatatcgctg gaggaatctc gcttttggca ctgattcttt
    38221 gcttcttctt tttagatgat cattacaatt tcatctatta cggaggaatg ctcctagtga
    38281 gtctgttatg cgtagtgcta gttgcagtga cagcacaccc cggagcaagt ttgaatcgat
    38341 ggctgacaaa tccagtattt acttggattg gcaaacgaag ctatggcatt tatctgtatc
    38401 agtttccagt tatgattttt tatgaagcaa aggtgactga tattgccgat catgttttgt
    38461 tgcatacttt agtggaaatc acattgattc taatcatcag tgaactttct tatcgatatg
    38521 tggagcgtcc gctagcacgt tttgattatg gtcgtacatt ccaagtgatg aaaggatggt
    38581 tcagcaaacc gatcatcagt aagagcaaac catgggttgt tccaggcaca ttacttgtag
    38641 caattgcact cgttggtttc gttacggcac cgaaaaacgc tgtaacagcc gatcaaaaac
    38701 aactgcaggc aaaaatcgct gaaagtaaaa aattagcaga agaaaccaga aacaattcag
    38761 aaaacaccac tagttcggtt gaccaagcga tccttgataa gtacgagttg tccaaggcac
    38821 aagggaataa ggcacaaaaa ttagaactaa cggcatttgg tgattcagtt atgttggatg
    38881 ctgcaacgga tctacaagaa ctttatccaa aagtagtggt agatggagat gtcggacgac
    38941 aattatatgc cagtgtaccg tacattgaaa aattaaagga acaagatttg ttgaaagaca
    39001 ctgttctgat tggactagga acgaatggct cattctcgga agctcagttt gatagtgtga
    39061 tggatgcaat cggtgatcga aaagtatact gggtcaatgt ccgagtaccg acgaagcgct
    39121 ggcaaaatga cgtgaatgcg atgcttgaac agatgacgaa aaaatacgac aatatgacgc
    39181 tgattgattg gtacagctac agtaatgacc atagtgactg gttttatgat gatcaagtcc
    39241 atccaaatcc tgaagggatg acacattaca ttcacttagt cagcgaagcc ttgctaggag
    39301 gaagttcaag tacgaacagc agtgagacaa acgtgacaga atgatagcta caaaaaactt
    39361 caggcaaaaa catttgtttt tgcctgaagt ttttttatat ttaccgtgtt tttaacattc
    39421 atatagattc aggaagcaaa acggttgagt gtgtctgtaa ataacgttct ttttgttttc
    39481 gggtgagttt tttgaatgca gcttctgctt ttgttgcttc gcttcttgaa gaaaatactt
    39541 ctgcatggat catcttaaca ggtcttcttt tttgaagacg agtatattta gcaccagtac
    39601 cattgttatg ttcctctaat cgtctagaaa gatcggttgt atatccacca taaaatgtct
    39661 gatctttaca gaataatacg taaaaataat gttcatttgc catagagcat ctcacgaatc
    39721 tctgcagtgt attctccatc catattgtaa gtgatcaatg gtggagcgac tttgaatccg
    39781 tctaatttgc cttctttgat tccttcaact aacaaaatat ttgcctcttt tccaggtttt
    39841 gggtaaacaa attggatcct tttaggtgca attcgatagt cttccatgac ctgaatgatt
    39901 tctaagaacc gatcaggacg atggaccata gtaaagcgtc catttgtttt tagtagctta
    39961 cttgaaatat cgatcacttc ttctaacgtc gtatgaatct catgacgggc gattgccagg
    40021 tgtttattag ggttcgtttt atttgttggc agccctttga aataaggtgg attacagacg
    40081 actaagtcac aagaattatg tcgaacgaca gataagctgt ctttcagatc gatggtgtgg
    40141 acagtcattt gttcatttaa atggttaagc gcgatactac gtcttgccat gtctgctaga
    40201 cgaggttgaa gttcgatagc gtcgatagcc gcctgggttc gtttacttaa aaaaagtcca
    40261 actgcgccat ttcctgcaca aaggtcaaca atcttccctt ttttaggtac acgggaaaag
    40321 tgagcaagca gcacagcatc taaagaaaaa gaaaacactt tggaactttg gataatcttg
    40381 atatcttctg cgtataattg gtcgattcgt tcgtcttcgt gaagcatgga ttccctccaa
    40441 aatgaaaaaa atagtcgtct gtattatact atttttatta aaaagaacca aggtggcttg
    40501 tcaaacctct attttttatg catactatga ccataagaag ggaaaggaag agactatgtt
    40561 ttatcgattt atgcgcgggg tagttcgagt actattagcc ttagttaatg gaaatgcccg
    40621 ctatgagaat aaagaagttt taccgcaaga tgagaattac atactagttg ctccccatcg
    40681 tacttggtgg gacccattat atctggcggt agctgcagca cccaaggaat tcagctttat
    40741 ggcaaaagaa gaactgttca aaaatccagt tctgcgattt atattaactc gatccaatgc
    40801 ttttccagtt aaaagagaaa atccaggacc aagcgtcatt aaaacacctg taaagatttt
    40861 gaaatcgaca aatttgagtt tgatcatgtt tcccagtggg acaagacatg ctacagaact
    40921 taaaggcgga atggcattga tttccagaat gtctaaagcg aaaatcgtgc cagctgtata
    40981 tcaaggtccg ttgacacttg gggatctgtt caagcgtcag agagtgacag tgcgtttcgg
    41041 cgaaccaatc gacttatcag atatcaagaa aacggataaa gaaggtatgg cggagatcga
    41101 acgacgaaca caagcagctt ttgacaaatt ggacaaagaa gtgaaccctg atttcaaata
    41161 tgaagtcaaa aaaaaataaa atgataagtt tatgcgtggg cggtcttttg aatctactgt
    41221 cctgttcagt tcagactttt tcaatgaaaa cgagggagag acgtcaagtc tgccctcttt
    41281 ttgcgttcca atatgtaaaa tagaagacag gtgtcatgta atggatcaaa gtgttataat
    41341 aattagaagg acattttttg aggtgattga atgcgttttt tacatacagc cgattggcat
    41401 atcggaaaaa aactacaagg ttatgacttg attgaagacc agcgtcatgt actatcttct
    41461 atactagata tcgcgaaaga agaaaaagta gaggcaatcg tgattgccgg agacttatat
    41521 gataggagtg tcccagctgt tgatgccgta gaattataca atgaattgat ggtcgattgg
    41581 aatttaaagg aaaagatccc gatttttgct atatcaggaa atcacgatag cagtacgaga
    41641 ctttcagcgg gtacgccatg gttcagttat tcgaactatt ttttgcgaac acagctagca
    41701 gaagcatttg aaccagtcga gtttaaaaac gtacaatttt tctttcttcc ttactttgaa
    41761 ccaattgcag cgagattata ttttgaagat gacaatatcc gaacgatcaa gcaagcggta
    41821 gccaaggtga tagataaaat gcaggagcta tttgattcag aaaaaaaaca agtattgatt
    41881 agccattttt ttgtaatggg aagtgtaaaa tctgattcgg aaacgaaaat cgaagtaggc
    41941 gggttggatt cgatccctgg tgaactactt acaccgtttg attatgtagc actaggacat
    42001 ttgcataatc aagctgcttt gagacaggat aatgctcgct atagcggttc cccattgaaa
    42061 ttctctttat ctgagatcaa ccaaaaaaaa ggcgtatgga tcgttgacct gacaacaggc
    42121 ctggagttga attttaggga gatcgaaccc ctgcatgata ttgaagaaat aacagcgagt
    42181 ttcaaagaat tgctggatcc tgccttttat cagtccgtca atcgggagaa ttacatctat
    42241 atctatctca ctgatagaac gatcatcccg aatatgatga accagcttcg gcaaatatat
    42301 cctcgtattt tggggattga acgggcaaac ggtcgagcag aacaaacaaa gcgcaaacga
    42361 aaagtactag aaatgaaaga tcctcaaaaa ttagcagaag cattttttag tgaaatgacg
    42421 gaagagcagc taactgcaaa ccaagaaaaa tggctcggag aaacgttgca agaaatcatg
    42481 gaaatggaat gatcaagaat gaaaccgaaa aaattacaac ttaaaaattt tggtcctttt
    42541 atcaatgaga ccgtagattt ttcacgtttg acagaagcac cgcttttttt gatcagcggg
    42601 aagacaggag ctggcaaaac gacgattttt gatgggatca ccttcgcact ttttggtgaa
    42661 acttccggaa gacttcgctc tggaaaagag atgcgttctt tgtttgctac accagacgaa
    42721 gaaacaagcg tgactttttc ttttgaacat cagcagatga gctatgaaat cgaacgaaaa
    42781 ccagaacaag ttttagcaaa acgaaaagga aacggaacaa aaaaacaggc agccaaagta
    42841 acgttgacca tttttgatgg gaaaggaaaa gaaataaaac aaatcacaaa acgtacagaa
    42901 gcagatcagt tgatcagaga actgatgaat ctcgatgcga aacagttttc tcaaatcgtt
    42961 ttactacccc aaggagaatt ccgtaatttt ttggtttcat caagcagtga taaagagact
    43021 gttttacgtc atttattcgg tactcaattt ttccaacagt tcaatgagcg attaaaagaa
    43081 aaagcaaaac aacagcaaca aaaattggat catttagagc aagagctgca tcttctgcaa
    43141 aaaaggtttg ttttagtcaa agaagaggaa ccagcagcag ggtttgaagc cgttttagcc
    43201 caatggacaa accatcaggc aatactcgaa aaacaaatca cggaagaaaa agaagctcta
    43261 acggaacttc aggaaaaaca aaagcaacta gaaaattcct actatcgttt tgaaagcttg
    43321 aaaaaaagtt atgaagaaaa aacgatatta ataaacaagc aaaaggaatt agctgctcaa
    43381 aaagacgaaa tagaggaaaa gaaacgatgg attgggtatt atgaatttac gcaacgatta
    43441 gtcgaaccaa tccagcgcct acaagaaata aaagctgaaa aaatagaact gtcgcaaaaa
    43501 agtagtgagc aaacaaagaa actagcgatg actacgcaga attatgaaga gtggcaaaaa
    43561 aatgaagcaa accgcgtacg ccgacaaaca aaaatcaaag aagctgctca aaaactgcaa
    43621 aacaaacaga tgatggtgcc aattgtcgaa tccttacgta gtaaaaaaca agacgcagaa
    43681 caattaacaa tttcattgga taaagaagaa ttgaatgccg agaagctgta tcaaaatctc
    43741 gctatctatc aggaaagaac tcgaattctt caagaaaatt tactggatca ggaaaaactg
    43801 caagaagatc gtcttgcttt tggacagtta aaatatctag atgaaaagca gcaagaaata
    43861 gaaaaacaaa aagcaaaaga cactgggtcg ctcgcacaga taagagaaga actcaaaaaa
    43921 gcaactgaag aaataacaaa aaatagtcag ctattgaaag aacagacaga acaagcagaa
    43981 cagctgaaaa gccaatgggc aaagcagcaa attgctcgtc ttcagctttt tttgcgtcca
    44041 ggggagccat gtcttgtttg tggatcaacg gaacacccca tacaacaatt aaaacacgaa
    44101 cagccaaata aggaagatat cttaaaagta gaacaacaac tggcagaagc tgagtctgct
    44161 gtagaaagaa ctcagcaaat cattgccaaa agtgaagcac atgaaaataa tcttcaacaa
    44221 caattatcag atttagaaca aaaaatcatg gcaacgaata tacaattggc tgaacaagaa
    44281 gaacacttgc aacaggcttt gaaaaaggca tttcctgaga taacagaaca aaaaacaaaa
    44341 acagctcttg tagtaatcga acaatcttta gatagacgaa aaagcaagat ggccaatgca
    44401 agaatagagc tggaagaaat aagacaacaa gcagaaaagc tcgaacaaca attagctgtc
    44461 tacaaacagc agcagacaga aaaaaataat cagctccagc aactgcaagg agaaatcaaa
    44521 agtttagaac aacaattgca agatacggat agtaactgtt tagaagagga gatacgacga
    44581 cttgaaaaac agttagaaga agactcgaat caactagctg ttgagcagaa agcaggagtg
    44641 caattgttgc aagatcttca tacgcttcgg acacagcttg atcttcaaca tgaacaaata
    44701 gaaaaaatag atgaaaaaat agaaaaggaa caagaaagaa tagctaaaaa gttagaaagc
    44761 cagtcgtatt tttcaacaat tgaagaaatc tgtgcatttg cacaacagca agcacaatat
    44821 aaagaaaacc aacgtacagt tacttcttat catgaagagc aattagtgac agctgaccgg
    44881 ctgcgtcaat tagaaaatat ccagctaact gagacattcc cagatacaga agagatcagc
    44941 caacagttag aagaaataag acgtatgatc gaaataaagc aagaaaagat atacggttta
    45001 caagaacaaa aaattagtaa tcaaaaaatc tacgatgaat gtctttcgat ttatcacaca
    45061 agccagacga aattagatga gcttacgcaa ttacagcagc tttcgcaaac attcaacgga
    45121 gaaaatccta agaagactag tttggaacgg tatgtgcttc aggtttatct tcaagaagtg
    45181 ttacaagtag caaatgatca tctccaacgt ttaacgaaaa atcgttatca atttgagcta
    45241 gcggatacca ttggcagtta tcgagggaaa accggattag aaatcaatat ctatgatgat
    45301 caggcaggta tgtctcgaag tgcgcatacc ctgtctggcg gtgagagttt tattgcagca
    45361 ctttctttag cattagctct tgccgatgtg atccagacac aagctggtgg tgtagcaatc
    45421 gatgcattgt ttattgatga aggatttggg tcattagatg aagaagcttt ggaaatggca
    45481 atggaagctt tagaaacgat cgaaagtgaa ggaagaatga tcggcatcat tagtcatgta
    45541 agagaattga aagaacgagt attacaacaa ataagaattg atacagaagg tagcggacaa
    45601 agcaaaatac gctatcaact tggataaaaa gggagattgg taactatgaa atggagtatt
    45661 ccagaaaaag tcattgcacg tggacgtcaa tacttgcaag aaggccgagt gttatcggtt
    45721 gtccctgacc aagaagaaaa cgtgtggcat gcagaagtct tgggcagtga attgtatatg
    45781 gttgatttgg atggtacagc aaaagagata gattactgcc aatgtcctta ttgggaggaa
    45841 cataaatatt gtaagcatac agttgctgtg gaactttatt tacggtcgaa aaatctatct
    45901 cgtatcatga aaaaagacca gccaatgcta gaaccggtaa aagcaacaag tgagggagaa
    45961 atcattgcaa aaggtttttc tcgtctaaaa acacaaaaca atcctcaagc ggtgcaacct
    46021 ttgattattg aataccaagt agaaacgatt gagactaatc agtatcaccc agagctttct
    46081 attttggcac tttacttgcg tatcggttca ttggcatcac cgaaaaaaac atatatcgta
    46141 aaaaacatct atgatttttt acaagcttac gcagaaaaag aaacttacac tgttaataaa
    46201 cagtaccagt ttcgtctaga taaacgggcg tttcaaaaag aagatcaaaa aatactcacg
    46261 catcttgcag gaagtgctca gacgcatcaa ttattaggta cgaacggctt acaagtcaaa
    46321 ggaaaactag ataaaagata tctgcttctc ccagtagaac aagcccgctt cctgttagag
    46381 cagatgaatc agactacacg tttgcatctg cagataaatg aacaaaacga tcaaggaata
    46441 caattttccg atcaaaacaa acctttatca ttcaaagtgg aaaaatttgg agaagattat
    46501 ttgctgcaag cattgaatga ttttgatttt ttctttatgc attatcagtg gggagttatc
    46561 caagggacat tttattctct gacgaaatat caacaaacgg tttatcaaac ttggaaacaa
    46621 ttgattcgcc gattggagaa accagaagta gtgttcaaga aaaaagaatt accgtctttg
    46681 tttaaagaga ttatccctct gctttcagag atcggcgacg tagctattgc ccctgcagta
    46741 gaagaggaag tagcagatat ccccgtcgaa tttattttct ttttccgaaa atcaaaagga
    46801 aaaatccaag ctcgagtcga tttcgtctat ggtgaagtca tctattcgac tgacccgaag
    46861 catgaggtct cgacagaaca ggcttttcag gtgttacgtg acacagtaga agagaaacga
    46921 gtacttgatc tattcagaat gtatcgctac cagaaaaatg aaactggtta tgaacgtcca
    46981 ttgccaagcg gggaagaact atatgccttt ttccgcacag aactatctgt cttccgtcag
    47041 tttggtgaag tcagacttgg aagaaaattg cgagagttgt atttagatgc gcataaacat
    47101 caaccgaaaa tcgaagtaac cgagaccggt tcatggctcg atattcgatt cgatgtgaca
    47161 gggatagagg agcaagaaat cgatcatgtc ctgcaaagct tgctgagaaa tgatgctttt
    47221 tatacattag aaaatggtca ggttctttct tttgattcag aagaatttca acaaacaagc
    47281 caagtgttgc aacaattacg ggaatcgata cgtacagaag aaggaacgat ccatgtacct
    47341 aaaaatcaag gattgatcat tcaaaatcaa ttggaaaaaa gcaatgctac ttttagtgaa
    47401 tcgttccaaa cgatggtaca agatctcatt catccagaaa gataccaggc acagcttccc
    47461 aaaggattga atgcaacgat gagagattat caaaagcaag gttttcgatg gttgaagatg
    47521 ttaggtcatt atcagtttgg cggtatttta gccgatgaaa tgggacttgg gaaaacacta
    47581 cagacaattg cctttttact ttcggaaaaa gaagaacgga aaagcttctc tgctttgatc
    47641 gtagcgcctg cgagcttaat ttacaactgg caggcagagg tgagaaaatt cgccccttct
    47701 ttaagtatcc aagtaatcaa tgggaataaa aaagaacgtg aagaattact ggctaaagac
    47761 acagatatcc gagtgacttc ttatgccagc ttaagacagg atctagctaa ttatcagtcg
    47821 caaaaaattg attatttgat tcttgatgag gcacaaatgg tcaaaaatag cagtacgaaa
    47881 actgcacaag cattgagaga attagctgta cctcagcggt ttgcactgag tgggacacca
    47941 atcgagaata atttagaaga attgtggtca ttgtttgcaa cgattatgcc aggatttttc
    48001 ccgactaaaa caaaattcag ggaacttgcc gcagaagaaa ttgcgcaaat gattcgaccg
    48061 tttattttac ggcgagataa acaaactgtg ttgaaagact tgccggaaaa aacagagatg
    48121 aatctatatt ctgcacttac agaagaacaa aaaactgttt atttagctta cttgcgtcaa
    48181 atgcgtgaag aaatcacatc aatggattct gaagcattca agaaaaaccg gatcgggata
    48241 cttgctggtc tgacaagact gcgacaaatt tgctgcgatc ctcgtctgtt tattgaagat
    48301 taccaaggcg gttccggcaa gctcgaacaa gtaaaagatc tactggtagc tgccaaagag
    48361 aacaaacgaa gagttttgct gttttctcaa tttacaggga tgctgactat cttgcaagaa
    48421 gagttagccg agctagggat ctcgacattt tatttaagag gcagtacgaa accacaagat
    48481 cggttaagta tggtagacgc atttaatgct ggcgaaaaag atgtttttct gatttcctta
    48541 aaggctgggg gaactggatt gaatctcacg ggagcagata cggtcatctt gtatgacctt
    48601 tggtggaatc ctgccattga agaacaagct gctggacgtg cacatcggat cggacaaaaa
    48661 aatgtggtag aagtgtggcg tatgatctct gaaggaacga ttgaggaacg catggattca
    48721 ctccagcaag aaaaacgcga actgttccaa aaagtgatcc aaggtaatga agaacagttg
    48781 acgaaactga ctgaagaaga catccgcatg attttaagtg taggagaaat cgaggagtaa
    48841 gagactcgaa aaagcgttca gtaatgggta agaaagcctt tctaaagaag cgattgttta
    48901 tttgatttaa aaaatagcaa ggaggctggg attccatttt atcccagctt ccttgctatc
    48961 atttttttat ttctattttt aaaggttata caaagattgt cttcattgtc tctaacagct
    49021 gatcaaaaga agaaatctcg atatcgcaaa ttggagtctg ttcaattttg cgttctcgat
    49081 ggttgaacca aagcgcttgc cagttagcac tttttgcacc tagaacatca ttgtcgtaat
    49141 tatcgccaac gtataaggtc tcttctggaa gcatatgaaa ttctttctca gccagctgaa
    49201 aaatctcttt ttctggtttt tggaaacctg ttgcttgaga aatgagcata ttgcgggaag
    49261 gaatccaatt gttcaattga agttgcttca gtttttttgt ctgatggtca gtcggcccat
    49321 ttgtgataat tcctaatggg acattctttt ccttcaagaa atcgagggtt tttttgacct
    49381 cctcatgcaa gcagatatta tcaagttctt cctcgtaaat tttttgaaat aagaggccat
    49441 cttcttccgt aatatgaggg tagtctaaat cttttagtga ttggctgatc cgatgtgctc
    49501 gcatatattc tagtgtccaa tctcctgcca ttacttttgg gaagttttca tcactatgat
    49561 ggcggaaccg gatatatagt ggatgcatat ctgcatctga aacaagcgga acgactcttt
    49621 tgaccgcgtt tcgaaatggc tgctgctgat catacatcgt atcatcaaca tcaaacacaa
    49681 ctgatttaat caaaatttta cacgcctttc ggttttcatt gattttttca caaatccttg
    49741 actattgtaa cagaaaaaat tgtctaaaaa agctgataaa taaaggtttt tcttactata
    49801 tttctatttc cttgacagaa taaggttttt atatttcagt ttttttcact aaaaatcgtg
    49861 aaacacgtca ataagtttga tgaacaaatt aatcattatg gtagaagtcg attgatttat
    49921 tttaatgcaa tctctgtgga attttcgaaa gatttatttt tttaatacag tctcaatata
    49981 actattcaaa cataaaataa cgttatttga tttatttgtt tatagtaaat ttt
//
LOCUS       DAZULR010000020        47851 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.020, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000020 DAZULR010000000
VERSION     DAZULR010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 47851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47851
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.020"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(38..1189)
                     /locus_tag="ACG8ZV_001269"
     CDS             complement(38..1189)
                     /locus_tag="ACG8ZV_001269"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HFS4996620.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(1202..1639)
                     /locus_tag="ACG8ZV_001270"
     CDS             complement(1202..1639)
                     /locus_tag="ACG8ZV_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFS4996621.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            complement(1654..3420)
                     /locus_tag="ACG8ZV_001271"
     CDS             complement(1654..3420)
                     /locus_tag="ACG8ZV_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol-specific transporter subunit IIBC"
                     /protein_id="HFS4996622.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEALATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            3684..4361
                     /locus_tag="ACG8ZV_001272"
     CDS             3684..4361
                     /locus_tag="ACG8ZV_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFS4996623.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            4364..5491
                     /locus_tag="ACG8ZV_001273"
     CDS             4364..5491
                     /locus_tag="ACG8ZV_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4996624.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLPLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(5691..6131)
                     /locus_tag="ACG8ZV_001274"
     CDS             complement(5691..6131)
                     /locus_tag="ACG8ZV_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFS4996625.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAKTIEEVQMIFEHGHI"
     gene            complement(6142..8175)
                     /locus_tag="ACG8ZV_001275"
     CDS             complement(6142..8175)
                     /locus_tag="ACG8ZV_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HFS4996626.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            complement(8177..9880)
                     /locus_tag="ACG8ZV_001276"
     CDS             complement(8177..9880)
                     /locus_tag="ACG8ZV_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFS4996627.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKKSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            complement(9974..10924)
                     /gene="manA"
                     /locus_tag="ACG8ZV_001277"
     CDS             complement(9974..10924)
                     /gene="manA"
                     /locus_tag="ACG8ZV_001277"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HFS4996628.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIATEPGK"
     gene            complement(10963..11988)
                     /locus_tag="ACG8ZV_001278"
     CDS             complement(10963..11988)
                     /locus_tag="ACG8ZV_001278"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFS4996629.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            complement(12197..13066)
                     /locus_tag="ACG8ZV_001279"
     CDS             complement(12197..13066)
                     /locus_tag="ACG8ZV_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFS4996630.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            complement(13525..15417)
                     /locus_tag="ACG8ZV_001280"
     CDS             complement(13525..15417)
                     /locus_tag="ACG8ZV_001280"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4996631.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(15414..17141)
                     /locus_tag="ACG8ZV_001281"
     CDS             complement(15414..17141)
                     /locus_tag="ACG8ZV_001281"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4996632.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(17157..17807)
                     /locus_tag="ACG8ZV_001282"
     CDS             complement(17157..17807)
                     /locus_tag="ACG8ZV_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HFS4996633.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            18011..18307
                     /locus_tag="ACG8ZV_001283"
     CDS             18011..18307
                     /locus_tag="ACG8ZV_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFS4996634.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            18479..19099
                     /locus_tag="ACG8ZV_001284"
     CDS             18479..19099
                     /locus_tag="ACG8ZV_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFS4996635.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(19191..20357)
                     /locus_tag="ACG8ZV_001285"
     CDS             complement(19191..20357)
                     /locus_tag="ACG8ZV_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFS4996636.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(20369..20722)
                     /locus_tag="ACG8ZV_001286"
     CDS             complement(20369..20722)
                     /locus_tag="ACG8ZV_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HFS4996637.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLETVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            20850..21872
                     /locus_tag="ACG8ZV_001287"
     CDS             20850..21872
                     /locus_tag="ACG8ZV_001287"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HFS4996638.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            21891..22052
                     /locus_tag="ACG8ZV_001288"
     CDS             21891..22052
                     /locus_tag="ACG8ZV_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996639.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(22311..22745)
                     /locus_tag="ACG8ZV_001289"
     CDS             complement(22311..22745)
                     /locus_tag="ACG8ZV_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996640.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLKKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(22855..24714)
                     /locus_tag="ACG8ZV_001290"
     CDS             complement(22855..24714)
                     /locus_tag="ACG8ZV_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFS4996641.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            24715..24855
                     /locus_tag="ACG8ZV_001291"
     CDS             24715..24855
                     /locus_tag="ACG8ZV_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoglycerate dehydrogenase"
                     /protein_id="HFS4996642.1"
                     /translation="MLAPSFLSIKECCFSYFSCTKFESKERKEELMKSKYSLSLWPFW
                     FL"
     gene            complement(24832..25992)
                     /locus_tag="ACG8ZV_001292"
     CDS             complement(24832..25992)
                     /locus_tag="ACG8ZV_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFS4996643.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(26299..27723)
                     /gene="araA"
                     /locus_tag="ACG8ZV_001293"
     CDS             complement(26299..27723)
                     /gene="araA"
                     /locus_tag="ACG8ZV_001293"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008733 - L-arabinose isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0005996 - monosaccharide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HFS4996644.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(27739..28437)
                     /locus_tag="ACG8ZV_001294"
     CDS             complement(27739..28437)
                     /locus_tag="ACG8ZV_001294"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019569 - L-arabinose catabolic process to
                     xylulose 5-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HFS4996645.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(28394..30055)
                     /locus_tag="ACG8ZV_001295"
     CDS             complement(28394..30055)
                     /locus_tag="ACG8ZV_001295"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004856 - D-xylulokinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0005998 - xylulose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HFS4996646.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKR
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            30273..31673
                     /locus_tag="ACG8ZV_001296"
     CDS             30273..31673
                     /locus_tag="ACG8ZV_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0051119 - sugar transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HFS4996647.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKVLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIIGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(31925..33004)
                     /locus_tag="ACG8ZV_001297"
     CDS             complement(31925..33004)
                     /locus_tag="ACG8ZV_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFS4996648.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(33090..34049)
                     /locus_tag="ACG8ZV_001298"
     CDS             complement(33090..34049)
                     /locus_tag="ACG8ZV_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HFS4996649.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(34061..35572)
                     /locus_tag="ACG8ZV_001299"
     CDS             complement(34061..35572)
                     /locus_tag="ACG8ZV_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046556 - alpha-L-arabinofuranosidase
                     activity [Evidence IEA];
                     GO_process: GO:0046373 - L-arabinose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-arabinofuranosidase C-terminal
                     domain-containing protein"
                     /protein_id="HFS4996650.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(35594..36157)
                     /locus_tag="ACG8ZV_001300"
     CDS             complement(35594..36157)
                     /locus_tag="ACG8ZV_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFS4996651.1"
                     /translation="MKIVETKFYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(36163..37026)
                     /locus_tag="ACG8ZV_001301"
     CDS             complement(36163..37026)
                     /locus_tag="ACG8ZV_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4996652.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(37040..37936)
                     /locus_tag="ACG8ZV_001302"
     CDS             complement(37040..37936)
                     /locus_tag="ACG8ZV_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4996653.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(38111..39400)
                     /locus_tag="ACG8ZV_001303"
     CDS             complement(38111..39400)
                     /locus_tag="ACG8ZV_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFS4996654.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(39372..40889)
                     /locus_tag="ACG8ZV_001304"
     CDS             complement(39372..40889)
                     /locus_tag="ACG8ZV_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HFS4996655.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            41087..41977
                     /locus_tag="ACG8ZV_001305"
     CDS             41087..41977
                     /locus_tag="ACG8ZV_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HFS4996656.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(42050..42874)
                     /gene="nadE"
                     /locus_tag="ACG8ZV_001306"
     CDS             complement(42050..42874)
                     /gene="nadE"
                     /locus_tag="ACG8ZV_001306"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HFS4996657.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(42886..44358)
                     /locus_tag="ACG8ZV_001307"
     CDS             complement(42886..44358)
                     /locus_tag="ACG8ZV_001307"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HFS4996658.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(44995..45357)
                     /locus_tag="ACG8ZV_001308"
     CDS             complement(44995..45357)
                     /locus_tag="ACG8ZV_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HFS4996659.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            45580..46332
                     /locus_tag="ACG8ZV_001309"
     CDS             45580..46332
                     /locus_tag="ACG8ZV_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFS4996660.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWLSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(46472..47395)
                     /locus_tag="ACG8ZV_001310"
     CDS             complement(46472..47395)
                     /locus_tag="ACG8ZV_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFS4996661.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYQKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(47410..47682)
                     /locus_tag="ACG8ZV_001311"
     CDS             complement(47410..47682)
                     /locus_tag="ACG8ZV_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996662.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT        13929 a         9944 c         8258 g        15720 t
ORIGIN      
        1 aaaaatttcg tcacattccc ctttttcgta tcctatttta agcgacttgc ttggcataac
       61 ggttcacgtt ttgcttgata ttcccgattg ttttcggatc attgattcct gtgacttctt
      121 gaatcaattg ttccaagttt tcatggatct tcatttcatg caattgacgg ctttgttcat
      181 cttcaggatc atagtaatta aaaataatcc ccattgttgc cgtcaaatgt gggcaagtca
      241 agttatgttc ttgtagttct ctcactggac gtgtaaatct ttcttgataa cctaacttac
      301 gtaatggtgt ccgagcgaca cgtgtgatcg catcagagat atttttgttt tggaagcgat
      361 gaatgatttt ttcaatatac gcatgatgct gctctgcatc aaacccccat ttggcaatca
      421 gcaaacttcc tgtttcctgc aaaactgatt ttaattgtgc cacaactaac gcatcttgca
      481 ttgcttcatc aatggtctgg taacctaaca aggcacctgt ataagcgaca gtcgcatgac
      541 cagtattgac actaaatagt ttgcgttcga tatatggttc tagatcatct acatataaaa
      601 ccccttttaa ttggattttt ttattttttc tttggctatc gtcaatgacc cattctttga
      661 aaggttccac ttggacgaat aaaggatctt catggtgttg taatgggacg attcgatcga
      721 ctgctgcatt tggaaagccg atatatttgt cagtaaatga tgtttccgga agatatttat
      781 acacttcttt ttctagaaat gctgaaccgc caatcatatt ttcacaggca atgatatcta
      841 aagatgttgt gcttccttcc ttttctcttt cttggatacc ttttgcaatc aactcagcaa
      901 taaaaggtaa gatattcggg ccaatggcgg tagtaactaa atctgcttca gcgatttctt
      961 ggattacttt ttctggattt gtttgattgt tgattccttt gacatttttt acagtgattt
     1021 tttcttttga ttcatctgct aattcgattt cgtattcttt tctttcattt aaagcatcaa
     1081 tgatcgtgtg attcacatct acgaaagtaa tctcaaatcc attagctgcc aaaacctctc
     1141 caataaatcc tcgaccgata tttcctgcac caaaatgtac tgctctcatt tttctctctc
     1201 cttaagcaat tgctagattt tccgttactt cttctttgct gagcgcgtct gctagctgga
     1261 caacattgtc catatcactg caataaagtg cgatttgctg tacaagttgc aaatgctcat
     1321 ctccgactcc tgcaataccg aacaaaacag tcgcaatctt ttcttcttct tcggtaccaa
     1381 aatctacacc atctggtact tgaacgacac agatgccgga ttttttcaca tatttttttg
     1441 cttcatctgt tccatgagga atcgcgataa aattccccat ataaacagat aacattttgt
     1501 ctctatctac catggcatcg atatattcct catcaacgca ccctgcttct acaagcatct
     1561 gaccgcaata gcggatcgct tcttctttgg ttttaaaaga tcgattgagc tcgatcatgt
     1621 cgaatggcaa actttgcatg ctgttttcct cccttaagct gtctgtttca aatattgtgc
     1681 aatcgattcg tatttttgcg gattgaccat gctgttgact gataaatgaa tggattgagg
     1741 tgcagccatc tgtacttttt ccgctaaact ttctttggct acgatcagtg aatcaggttc
     1801 atcttttaaa tcttggatat tgacttttct taacgggata gttaaatggt tcttgtctaa
     1861 tatatctttg agcacggtca tccccattgt tgctgatccg gaacgatcat cgtggacaag
     1921 tagaatctct ttgatttgtt tgatgtttgc tgaaagaaac tcttctgctg gctcattctc
     1981 aatttcagaa actgatgttt tctgcttgct gcttaattct tgaatgattt catcatatcg
     2041 aggtgaattc aaaaagtttt ctactgagac aaaacgcgcg ctcggtgctt tttgttttgc
     2101 tctttcttgt agttcgacct gagtaacgat caatgtattc gagtcatctg tcagttggct
     2161 gattgcttga ttggtcaccg tttgaggcaa gtctgcttcc tgtacttttt ttctcaagat
     2221 cgaagcgccc atcgcacttg atcccattcc tgcatcacaa gcaaaaatga ttttttgtac
     2281 gccagagaat gtagctcctt gaggaatacc ttgggcacct ttggaagctt gcttagctgc
     2341 ctttgtctct tgaacagatt tttcgaagtc ttcatttgta tctttcgcat ccgctttcaa
     2401 aattactgca gaaataccaa acgaaacagc tgcggcaaca atcacgccca aaataacagg
     2461 aaggtaagaa ttgaacggtg tcatcgctag aatcgcaatg atcgaccctg gagaagctgg
     2521 cgctcttagt ccagcatcca tcaattggaa aatgaaactt cctgacattc ctccgcctat
     2581 aactgataag aataataacg gtttcatcat aacgtaagga aaatagattt catggatccc
     2641 gcctaaaaag tgaatgatca tggctcctgg tgctgaagat tttgctgctc ctttgccaaa
     2701 caaagtaaaa gcaagtaata cgccaagtcc tggaccagga tttgcttcaa gcaagaatag
     2761 aatagatttt ccagcctctg ctacttgttc agttcccaat ggtgtcaaaa tcccatgatt
     2821 gattgcatta ttcaaaaata agatttttgc tggttcaata aaaatacttg tcaatggaat
     2881 caaatgggca gataaaatga tctctacacc ttttgccatt gcttgagtca atgcatcgac
     2941 aactggacca atcgcagaaa aacctaataa cgctaatcca aaaccgataa gacctgctga
     3001 aaaattattg actagcattt caaaaccgga tttgatccgt ttttggaata gctgatcaaa
     3061 tttcttgatg gcatatccac caagaggtcc catgatcatc gcgcctagca tcattggaat
     3121 atctgttccg acaatcacac ccatcgttgc aattgcccca acaactgatc cgcggtcacc
     3181 agcaattact tttccgccag tataaccgat caataaagga atcagataag ttagcattgg
     3241 gcttaccatg gtagccaaag cctcatttgg taaataacca tctgggataa atagagccgt
     3301 taatacaccc caggcaatca gtgctccaat atttggcatg accatgcttg ataaagtact
     3361 gcctaatttt tgtaccctcg cttttagcga aatgttgttt ttgggaatcg tccgttccat
     3421 tttgtctctc cctctctcct tttgatactc taattgtatc cgcttactaa aaagagaaat
     3481 agtcgtactt tggcacgaaa ctttgtgcca aaggtttgag tatgtcagca aaataaaaag
     3541 atttcggtat cagaaaactt caattttaaa taaaactgtt attttaattt ttttataata
     3601 tgcaaacaat aacttttgtt agcatttaat ttagatgttt tccattctat tatgttatta
     3661 aattttatat tggaggccta tctatgacat tactgatcaa aaacatgaac atgaaacgtg
     3721 gtaaaaaacg tgtgattcga caattgaatc ttttagtaga atcaggagaa gtagctgctt
     3781 tgattgcccc gaacggattt ggcaaaacaa ctttgctgaa tggcattgcc caactgctgc
     3841 caacaactta tgatcaattg tcccttcaca acatctctcc tactgcttat acagattatc
     3901 gccggtcttt cttttttcta gaatcaacga atcagttatc cgactatcta tcggctgttg
     3961 attatttgac tttgatcaaa tactattggc agagcaaagt agaatgccaa actgttttcc
     4021 aacgattgaa gatgactgag taccttactt tgccgattgg aaaaatgtct ctaggaatga
     4081 aacaacatgt cttgcttgct gcttacttga tcagtgattc atctgtcatg ttattcgatg
     4141 aaccgttgaa cggattagac ccaggaagta ttgatatctt gaatagcctc atcagacaat
     4201 ggcagaaaga ggggaagacg attcttcttt cttcccacgc tatcgcgaat atccaatcga
     4261 tttgttctaa agcatgtttt ctaaaaaatg gagaaatcgt cacagaatcc tcaaatatgg
     4321 aagagatttt agctatttat cgtaaattat atgaggtgta actatgtctt tacttacatt
     4381 tgaacgcaat ctcttactaa aaaacaaagt aaacttttta tttcctctat tgttggtcgt
     4441 gctctttgca ttcccacttt tttttgatca taaacttgct tatacagaat tcgatgaact
     4501 gaatcataac tatgaagaga tgcaacgttt gattgaaacg ttgaaagaag atgagaatga
     4561 gaaagaattt gtggaaagtt tagagaaaag caacaaactg atcgaagcaa tcttacatgc
     4621 aaaaaacaca gggaatgtcc agcaaatggt cgaagcaact tatcattatg aaaaagatat
     4681 actggatcga ctgatttctg gtcaaagaca aggaattcca atcattgaac aacaaaaacg
     4741 tgtcgagttg ctccgttata tgaaagaaca tcagatccaa agatattcta tttttgactt
     4801 gccagcgcat ctccctttag caaattacta cgaaaatatt ttttcaggaa tgatttctag
     4861 ttttttgatt ttatgtataa ccgccttgtt tctttcttcc atcatctctt atgaaaaaag
     4921 aaagcaggta atctctctag tcaatctatt accggatagt atggtaaaga aacatagcat
     4981 ccgttttacc atttattatg gtgcagctat gctaagtctc gtgatgccat ttttgatcgt
     5041 ctctatacta gtaataatca aaaatggttt gggagacttc cgttatcctg taggaacgat
     5101 cattggtcag gagatacgaa tccttccgat gtatgagtat cttttccaga gctttctgtt
     5161 cctgttgttg tgggtgctct ttttaagtac aatcagtttt cttctatctg ctttatttga
     5221 acattctcta gtcaatcttt taggtacact tctttgtctt ttcttagcag agtatcgctt
     5281 gttttcttcg attggatgga tagaatcaat cagtcattac ttgccaactt cttatgttga
     5341 ttttcaaaat gtgatcatag gaggagatat tttctcgcca ctagcttcag aacaggttac
     5401 tttcatgaat ggtatcttga cacttggtat atggagtatc gttttattat tcataggtat
     5461 gggcactatc tatataaaaa agagctatta aaacacaaaa ataatagggg cggtgacaaa
     5521 aaccttgtca ccgtccccta tttcaaataa acggttttct agaataaata gttttcaaaa
     5581 gcttgcatcc gcagtaataa gaacctccca acaaaaatag ctcctcttat ttttatcttg
     5641 gttgaagtta ttacttgatg caaggcagct ttttttactg tgaacattgg ttatatatgt
     5701 ccatgttcaa aaatcatttg gacttcttca atggttttcg catcactgag cgccattact
     5761 tggtcgatgt ctgaacagaa aaaggctaaa tcttggagca ccgctaactg atgttctttt
     5821 tttaaagcca ctacaaataa gagtgtcgcg atttttggtt cctcttttgt tccaaagtcc
     5881 acaccatcag gcacttggac taaatagatt ccttcttcta ctacttcttc atctttgtca
     5941 gtcccatgtg gcaaggctac gaaattcccg atatagacac tcgctttttc ttgtctttcg
     6001 atcattgatt ggatatatgc cggtttgatt cccccttgtt gggtcatcca ctggccgatc
     6061 tcggtcaacg cttctttcca attttgatag gattgatcga gcaatatttt ttctgctggt
     6121 agctgtatca tcttttcacc ttcatttctt tatttcttca atcaggattt tcgctaacaa
     6181 ctgataaacg atttctttat ttcctgagcg gaagatctcg gtgttcaagt cattcatgat
     6241 gattgctcca ctgatctttc ctaaaagaat cccgtctttt tcttggattg gcgaaggcgc
     6301 cagcataact aacatacggg acaaatcgac tggctgtcta tccatccctt caatggtcaa
     6361 cggatgtttc aaattgaaaa tacaaaagat cggtttagaa atcaatgagc tggatgtatg
     6421 gaataacccc atatttgtat gaggaatacc gataggtgct tgttcatatc gcttaagcag
     6481 ccggcgatga accacctctt catccgttac tagtccttca ggaaaataag gaaataagct
     6541 gcgaatcgtt tcggaaatcg tctcaggatt atccagttct tggataaaaa aacgaccgag
     6601 taattgattg atttgatcca tgaaatgcat tgtttcctca taagtatctt ctatcatcca
     6661 ctcgttattg ctgttatacg taattttttg cctttttttc ttctcaatat gcgaaaaagc
     6721 ttcttttagc tgcttgactt catcttctag cagtagcggg gagactaaaa tatattttcc
     6781 accgtatcct ggtaaaatag atgtagaaat aacaacatca tattcttctt gtaaatcgat
     6841 tttttttaaa tcagcaatcc gatagaaatg aatttgttgg atgaagggaa aatacctttt
     6901 caatcgtagt tccaacatgc tagtagaagc taatccactt ggcgaaaatc ctgcaatact
     6961 gatattgctt tctttcggac ttcgttccaa tgaattcgca aaatgaagga ccatataagc
     7021 gatctcttct tcggataatt ttttttcttg aaaaatccgc tctactgctt tacggattgc
     7081 attcgcaact tcctcgtatt gaaccatgat tttttctaaa atcggattgg tcagtgtctc
     7141 ttcttgtaaa acggctcttg aaaacacacc agataaatga gtcaacagca ttttgtacaa
     7201 agtttcatct tcataaaaat ggacattcgt ctcttcactt acttcttgaa tcagttgttt
     7261 tactaaataa gcaagctgtg tatcgaacgt ctcttcaaag aaattctgat caaatgagtt
     7321 cgtgaagtca tttaataatc ctgcaaaaaa gacgatctca tttactggat aaagttgttt
     7381 tgtctcagaa gcgatccgtg aaaacaatcg tttagctgtc tgtagtaatt ctttgtttgc
     7441 cagactatta tatgtctcat ttgtcagtaa atgattttta gtcacacgct ccatcgtcaa
     7501 tgtcagcatc aaaaccaaat gttcaagctt tctatcactt agattggtct ttttttggat
     7561 caattcttcc ccgattactt tgcgtgcaag agatagatgt tgcggatcaa cgaatcgaaa
     7621 aaaataattc agtgatgcat cgaaagaaat actatgaaaa agttcatatt cattgatttc
     7681 taattctaat acattcgctg tcagaagccg gcggtatttt tccggtcctt cgatctcgta
     7741 tccctggttc cgaatgattt ccaaaggcag ttggcgaata ctttcttcca actgtttgat
     7801 atctgcataa aaagtggtat tactgatgcg atatgattcc atgaaatgag caagactcaa
     7861 cggctctgtc gtcagtaaca actcggctaa aatcgcgtgt tgtcgtttag cagtggataa
     7921 gtcattactt ttcccatctg tattttcttt taattgctct aatacttctt ctgatgcctc
     7981 aatgacaaat gagcctctag ctgctttttt caaagaagca tttaccgatt tcaatgagac
     8041 ttcaagatta tctaattcgc ggtaaatagt ccgtttactg accttcaata aattcatcat
     8101 tttttggata gatacaggtg acgggctact gagaaattct gctaataatt gtttttctct
     8161 gggcgataaa tacatcttat atttctccct tcacgagttt ttcgtattca ttcgtagcta
     8221 cccaatgttc aactagaact agccgaggga tcttttcttc tagctgttca gttacagcta
     8281 gttctctttg tgcgatataa atcgtttctt cttggatttt gattttttct attgattctt
     8341 ttgagataac aaactgtttt ttcgcttttt ttgctaattg acttaaaatc gtcatgccca
     8401 tagtttgtga gccgcgtctg ttgtttttat acaaaaatac aatattagca ggcgactttt
     8461 tttgttctgt gatatctgct atctcttttt tttcttcccg ctttggaaat tggatcgctt
     8521 cttttattcg tgacagcaag atatctgttt ccaaaaagtg atccagtaca tagatttgac
     8581 tttgaggtac tttttctctt gcaagacccg ctagttcatg ttgcacgata accagctgat
     8641 ttacttggtt attcaattca tagatagagc tgtatccgac agaaagatcg attttttctg
     8701 ctgctaattt ctttttcagc agggcggctc ccatagcact tgatcccata cctgagtcgc
     8761 aagcaaaaat gacggaatga atgatagatg gttccaagat ttctcccctt tctttgaccg
     8821 ttttgttctc tttttcttta tttggtaatt tcaatagtat cgctgcacaa atgaaggtca
     8881 caaatgtact gattgctatc cctatactta ccccagctag ttgtggataa ggcgcattgg
     8941 caaaaatcac gagtagtgac ccaggcgata caggtgcagc taatcccgta tctaaccatt
     9001 gaaatatcaa cgtgccgctt gccccaccag ccattacagc taaaaataga tacggtcgca
     9061 gcaagacaaa tggaaaatag atttcgtgaa tcccgccaat cgcatggatc atcaatgctc
     9121 cactcgcatt tactttttcc tgtttttctg caaaacaaag gatagaaagt aagatcccta
     9181 aaccaggtcc aggatttgcc tccatcaaaa ataaggaaga gtacccgact gtttgtgaga
     9241 attcgattcc taaaggtgtc aatacaccat gattgattgc attattgaaa aatagtactt
     9301 ttagaggttc taagatcaga ctgacaagtg gtaacagatt cattgtgact agccaagaca
     9361 caacggaggc gagcaacaag tgaacactat ttaaaactgg ttcaataaaa acgattccaa
     9421 ttatacaaat aacgctacca gtcagtccta ctagtaggtt gctgacaagc atttcatatc
     9481 cagccttgaa tttcacgtgg aatctagaaa caaattgttc atatacgatg ccggcaagcg
     9541 gcccgataat catcgctcct acgatttgtg gagcattgga acgagcgatc aaccctaaag
     9601 aagcaattgc accggcgact gccccttttt gtccccctac cgatttcccg cctgaataac
     9661 tgatcaagat gggtaaaagc agctggatca tccaatggca tacctcttct aatgtggtgt
     9721 gcaaatcgcc agacacacct tttgttgcta atgacaagat tccccaagcg ataaacagac
     9781 ttagatttgg catgatcatt tcatttaagt gatgtccagc ttttctcagt tgtttcatag
     9841 acacgcgact gctgttgttt gctttccatt tgtattccat ctttttcacc atacttctat
     9901 ttattgatgg acggatttta tgtagaaaaa gcagcaaacg aaaaaccgtc tgctgctttc
     9961 agctatctgg gaactatttg cctggttcag tcgcaatgat tgctagttca ccttggaccg
    10021 cccactcaga aacgccattt ggaataatac agcttgttcc tttttctaat ggatatgttt
    10081 ttccgtcaac gacaaggtct cctgctcctt cgattaccgt catcaatgta taaggggctt
    10141 gttttttgaa agatgtgatt cctttaatat cccactcata tacattgaaa aactcagttt
    10201 ctaaataagt gacgatcgat gaattccctt ttcggacttc tttgatttgt aattctggtg
    10261 ttttcgcagg gacagttgtt acatcgatcg attgttggat atgcagctct cttgtttgtc
    10321 cttgcgcatc ttttctgtcg tagtcataca cgcggtaagt cgtgtcagaa ctttgctgtg
    10381 tttctaaaat catgattcct ttaccaatag catggatcgt tccgcttggt acataaaaga
    10441 aatcaccttt tttaactggt actttcttca aaaggtcatc ccagcgccca tctttgatca
    10501 tctcagctag ttcttctctt gtctttgcat gatgaccata gatgatttct gcaccaggtt
    10561 cagcatcgat gatataccag cattcagttt ttcctaattc accttcatgt ttcatcccat
    10621 aggcatcatc tggatgtact tgtacagata gatcatcttc tgcgtctaag atcttgatca
    10681 ataatggaaa cactggttct gaaggatggc caaacaattc cttgtgttct gaccatagtt
    10741 catctaatct tttccctttg aattcgccat tttctactac actgacacca tgaggatgcg
    10801 cactgatcgc ccaatcttct ccgattttat cgttagggat atcaaaacca aagactgaac
    10861 gtaaacgact tcctccccaa attttttctt gaaaaactgg ttttaaaaac ataggttcct
    10921 gcataattca aactcctctc atttttcata gctattatag cattatttcg gtaataccgc
    10981 tttctctttc aaaaagtttt caacaatttc atctcgacat atgagatact ccgcacgatg
    11041 atcgacagga tgtacgcgat ttgacaaaaa tatcaacgct tcttgtgttt ttatatcaat
    11101 caagaaaaac gtacctgtat aaccagtatg aaaaagaatc gcatgaccgt cttctacatc
    11161 cttttttaag tcccatccta aagaacgata gccatttttt ttcggtgttt gatcttgcag
    11221 taaagaatca atcgtctctt cttctaaaaa acgaccatta cggatttttc ccttgttcaa
    11281 atacatttgg acaaaagtaa tgctgtcttt caaatcaata aagagacccg cgttacctgc
    11341 atgttcagcc aaaactcttg ctttcggatc atgagtttgt ccacgcaaaa cctcacccga
    11401 aggcagttgt tctgtgggaa cgattttttt ggaaggaaaa ggaagaaata agctgttcat
    11461 cattcctaat ggttccaata cttgttcttg aaagatttcc actgcagttt cttggtaaat
    11521 ttcctctagc atcaacccaa gaagaatcgt accggcatct gtatatttta cttcttttcc
    11581 tagttgctca cctggttcta gcttcaaata agcggcgatc aattcttcct gagatagctt
    11641 atctctgttt ggtatccatg ttttgatatc agaagtatgt gtcagtaaat gacgcaaagt
    11701 gattgtctga ttttcaaatt caggaagata tttatgaagc ggttgatcga gttctatctt
    11761 tccatcttct aatagacgta aaactaatga agtggttgca acgactttcg tcagtgaggc
    11821 tgcatcaaac aacagatctt ctgtcatcag ctgcttttca ggaacgactt gggcaaagcc
    11881 ggctgtaaat gtttctactt gattttcttt tatgaaggcg actgctacac ctggataaaa
    11941 tccttcttcc atctttttca aaataagctg tttcgtgtgt ggatacatct ttttctcctg
    12001 cttttctatc agattcttac agtccaagct taaagcttaa tctatgagga atcaaccttt
    12061 tttacacaaa aaaactgcgc gaaaaaccgc gcagtttccc ccggtatact attttctctt
    12121 tctatctcta gaataagcga tagtatgacc gttcataaaa tgacgagaca tgcgacaatc
    12181 gttaagaaag aaaaagttaa gcgtcgcatc gaatgtcagt tttattcttt tcttttggct
    12241 cactgacgaa ccaccattcg attcctatag catcatagat tgtgagtact gtgtgctttt
    12301 tgtctaagaa gaaatcaact gatagttgct gcaagtgagc aatcagtcct tccatgcttt
    12361 cagtatcgat catgaatttc agaaaatcaa gtccaatcac ttcatctgta ggcaaatcaa
    12421 ttgcgcctcc gctagcttct gtcaaaccaa catggaaatc tccttcattc aatacatgga
    12481 tgccctcttc ttcattatgt accttcaaac caagtacatg attaagaaat tggcgttctt
    12541 ttgttaagtt agtaacattt aaatggattt tttcaaaata agaacctgtt gatagtttac
    12601 tgaatttttc ttcagatttt cttaataatg cttcttgatc cattgtttct ggaatttctc
    12661 tttggtcgtt cttattctct tcatggtaaa tttccaattc attctcttct gggtctacga
    12721 gcaaaatccc catacgtcca tgatcttcta aagcttcttt gattggataa ttcattttac
    12781 ggatacgaca aaggatatct gccatttctt ctgtgctagg gataatcaat gaaaaacggt
    12841 tcagcttttt gatcaccccc atgtgatcat tcgctctagg actttcttcc agcagcaaca
    12901 tttcacttcc agcttcttct gttcctaaaa tggctaattc gttttcttct cttttcaaat
    12961 caaagccaac aacgttcttg taaaaatcaa tcattttatc tcggtctttc acccgaatgg
    13021 ctacactttt taaataggtg gcagccccca attgaaaatc tttcatattt cttgctcccc
    13081 tctacgtcaa gctttatttt aacgatggat tcttcttctt tcaagcaata actttgattt
    13141 tgttaaaaaa aatgtgagaa aattcgcatt ttgcttgttt tttgtaaatt aatgagtaaa
    13201 aactcttata aaaagaggtt gtgaaaaagc tgttctgcat caagtaataa gaacagccaa
    13261 acaaaaatag ctcctcctat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt
    13321 tgaacaccgt ttaaggaaga ggttgtaaaa tcagcggttt gacctgagta ttagagatac
    13381 aaaacggaaa aatagcttct catattttgc cgttttttga gctaataccg aaggacagct
    13441 gattgaacac cgtttattcg gaaaaaggga ctgtgacacg acttttgtca cagcccctaa
    13501 aaaaaataat aaatttgtac tattctatga agcttcttct tcagaaaact gactgttata
    13561 aagatctgca tagaatccgt ctttttccat caatgtatcg tggtttcctg tttctacgat
    13621 cgaaccatga ttcatcacaa taatgttgtc tgcatcgcgt attgtagaca agcggtgagc
    13681 aacaacgaaa cttgtccggt tttccaatag gcggttcatc gctttttgaa tcagtatttc
    13741 tgttcgtgta tctacactag atgttgcttc atcaaggatc aggacatctg gatttgctaa
    13801 gaatgcccgc gcaattgtga ttagctgacg ctgcccttgc gaaatattgc ttgcatcctc
    13861 gtttaataca gtgttatatc cttctggcaa tttacgaaca aaatcgtcta cgtgagcagc
    13921 tttagcagcc tcaatgattt gttcgtctgt tgcatcgtcg ttcccatatt tgatattgtc
    13981 atagatactt cctgtaaaca gccaagtatc ttgcagtacc attgaaaact gtgcgcgcaa
    14041 ttcatcacgt gaaagatcac gggtatctac accatcgtaa cgaatactac ctccagaaac
    14101 atcgtagaac cgttcaagaa ggttgatcag tgtcgtcttc cctgcaccag tcggacctac
    14161 aatagcgacc atctcaccag gtttgacatc caagttaaaa tcagtcatta gcaagttatc
    14221 tggtgtgtag ccgaattgaa cattttcaaa acgaactttg tatggtgtat ctttttcttc
    14281 tggaaggcca gatttttcat tggacatctc ttcttcatcc aacacttcaa atacccgttc
    14341 ggctgaagca actgttgatt ggatagtgtt catcaaactt gcaagttgag tgattggttg
    14401 agagaactgt gttgtatatt gcaagaacgc ttgaacatcc cctaatgtca tgttcccatt
    14461 tgcaactttt actccgccta gtacagcgac gaacacatag cctagatttt taacgaaatt
    14521 catcaacggc atgatgattg ccgaaataaa ttgagctttc caaccagcgg catacagatt
    14581 ctgattttct ttttcaaata cttcctggtc tttttcagta tgattgaatg ttttaacaat
    14641 ggtatgacca ccatatgttt cttctacttg gttattcaat aaacctaaac ttttttgctg
    14701 atctgcgaaa aacacttgtg atttcggcgc tacgatcatc acgatgatca agcttaaagg
    14761 gatcatcaat aacgcgacta acgtcaattg ccagctgatt gaaagcatca tcacgatgac
    14821 cccaatcaat gtgactgcac tagttacaaa ttgagtcaaa ttttgctgca gcgtgcttgc
    14881 gatgttatcc atatcattga ttgctcgaga catgatatcc ccatttgtat gtgtatcata
    14941 ataggaaatc ggtacacgat tcattttggc ttccaaatca tgacgtaatt cataaactgt
    15001 tcgttgggaa acacgtgtca taataaattg ctgtaaaaag ttgaatacag cagaaatcaa
    15061 atacatcacg attactgtcg caatgatctg cgcgatttta tcaaagtcta tcggaaattt
    15121 tgttacttgt tggccttgtt gcatctgttg agcgccagcc attacacctt tgaatatttc
    15181 tgtggttgct ttccccaaga cctttggtgt ttggatttgg aagatcacgg ctgctattgc
    15241 tagtacaaat acagcgatga tcgcaaccat acgtttagac atatagccaa acaatcggcg
    15301 taccgttccc cagaaatttt taggcttttc accttttaca ccgagatttc tgccaggtcc
    15361 accatgtcct ggaccgcctg ctggtccatg agagggacgt gtgtttgttt tactcatgct
    15421 aagtcctcct ctcttagttg tgaatgaacg atttcttgat aagtttcgtt tgttgctaat
    15481 agttcttcat gtgttccttt gccaaccagt tttccttcat ctagcacaag gatcatatct
    15541 gcatccatta ctgtacttac tcgttgagca actaaaacgg tgatactttc tttcatattc
    15601 gttttcaatg cttggcgaag attggcatcc gttttgaaat ccaacgctga gaaggaatca
    15661 tcaaacacat agatatctgc tgttttgact aatgcccgtg caattgccag acgctgtctt
    15721 tgtccaccag agaagtttcc tcctccttgt tccacatggc tatctaagcc atcttccatc
    15781 tctgaaacaa aatctttagc ttgtgcgatt tctaatgctt tccaaatcat ttcatctgtt
    15841 gcatccggct taccatactg catattgtct cggatcgttc cagagaacag aactgctttt
    15901 tgaggaacaa agcccattaa ttctcgcaaa ttatattgag tcatgtcact aatgtccgtt
    15961 ccatttattt ggatcgaacc agattcgatg tcatataatc gagggatcaa attgactaag
    16021 gtcgttttac ctgaaccagt cccccctatg attgcgacga tctcgcccga cttggcttgg
    16081 aaatcaatat cttccaatgc aagtttttct gctccatgat atcgataatt gacatgattg
    16141 aaggccaatg ttgcgttttt tccagcaaaa gaaactgttt taggattttc agggtcatgg
    16201 ataccgattt tttcatccaa cacttcatta atacggtcag ctgaagcttg tgcacgaggc
    16261 accatgataa aaatagcgga aagcatcata aagctgatca agatctgcat cgcataagtc
    16321 ataaatgcaa tcagattacc gacttccaaa gtcatatctg ctatgtagtg tccaccaaac
    16381 caagtgattg ctacgtttgt accgctcatg atcaatgtca tcattggcat catcaatgcg
    16441 acgatcgtat taactttgat tgccgtattt gtataatctt tattcgctaa atcaaaacga
    16501 ttttcttcaa agcgtgtctt atcgaatgct cgaatcactc tgacccctgt caatccttct
    16561 cgaaatacca ggtttaaacg gtcagttttc ttttgcatac ttttgaataa tggaacagca
    16621 aagtacatga ttccgccgat caaaataatc attactggga tgacaactaa gaagattttt
    16681 gtcaactgat gatctttttg ataagcaagt atgctcgcgc caatcaacgt gattggtgca
    16741 ttgatcatca tacgtaaaaa catttgtgta accatttgga tttgagtcac atcattggtc
    16801 gttcttgtga tcaaagaggc cgttccatat ttatcaaacg catcttttgt cagactctct
    16861 gattttttat agacatccgt acgcaattgc ttacccagtt tctgtgattc acgagtagca
    16921 aaaaatgtat ttgcgatagc agctaagata ctgatcaaag aaaagccgat catcacaaaa
    16981 cctgtatgcc aaatataatc gacatctcct tgcgctaccc ctttatcaat aatattggag
    17041 gtaagtgtcg gcaaatataa atctgccagt acttggatca ccatgaaaac tgcagctgca
    17101 attgctgaag tcaaggagat ccgttttacg atttttagca tctagttccc ttctttctat
    17161 ttatatactc cgtttttcag ccaagaaagt ttcaaattga attcactgat tgcttgctct
    17221 actgagtaat cttcagatgt tgaaaataag cgatacgaat gcgcaattgt tgtaaataca
    17281 gtattcatca ctaattggat cagtaattcc aattcatgat cattttttac tttcagcttc
    17341 gtccgatcga tcaattcaag caactctttt gcatcttgtt tgtgttcttt atgtggatcg
    17401 tgaggcgttt tttggcgact cgtatgagga gcgacttttc ttgaggcacg gtaatccatg
    17461 ttcataaaca agttacgata aaaagaagca ttctcgcctt ccaaaatctc ataaatcatt
    17521 ttagaaaaat aggattcgaa tcctttgaat agatcaccat cggattcttt cattagttgt
    17581 aacatatctt tagagctgtc acgtctcatt gtctcaaagt aataaaaata aagatcctct
    17641 ttatcttcaa aatactgata gaaactgcct ctagggatat ccgctaattt gacgatatta
    17701 gcaatcgaag cttcttttaa gggtactcta gaaaactcga ttctcgcagc ctcgattagt
    17761 cttttttgtt tttctttagg caaatggaaa aatgtctgtg tcggcatatg gatcctcctt
    17821 tctttcaaga tgacacattg tcatatgacg ctgtgtcatt ataacacctc ctacctgttt
    17881 tgcaagacat ttgcatagtt tttttcatta tcatccgata cattaaaaaa gtgataagag
    17941 gaatccttcc atttgaatta atgagagttg cccattaaaa tagccacata ctaaacaaag
    18001 gatgagataa atggcccaat caattagtgt ccaagacttc aataaattgc ctctcgatgc
    18061 tgacagcatc gttttagata caagaaatac cttagattac acaaaaaacc acttaagcca
    18121 ctcgctttct atccccgctg ctatcttgcc aagacaatta aaaaatctag atccaaagaa
    18181 actttattat attctaagct atacaggcag gcgatcagaa gcattagccg atcaacttac
    18241 tgctaatggt tttcgtgctg tttatatcat tggtgggatg gaagctcttc agtcgagtgt
    18301 tgcttgaata ttgcttgtta gattcaaaag aggctgtgac aaaaaatcgt gtcacagcct
    18361 cttttatacc ctgtcttttt ttagttattt attcttcaac cttatcaata tgacttgata
    18421 gccttttctt tttctcatag ttataacaat catagcaata aaaggagaag gtaagcatat
    18481 ggcatctgtt ttagtagtca aaggtcatcc cctaactgca gaagaatcgc gcacagttaa
    18541 ggcattgacg tcttttttaa caagttataa agaaaatcat ccagatgatg aagtgactgt
    18601 tttggaactt tatcgcgatg atattccgga aatcgatgaa gaattattat caggttggga
    18661 agcattacgt gctggtgcag aattcacttc cttatcagaa agtcaacaac aaaaaattgc
    18721 tcgtttcaat gaattgactg atcagttcct tgctgctgat aaaatcgtta tcgcaaacgc
    18781 cttatggaat ctaaatatcc caacaaaatt aaaagcttgg ttcgataccg tcaatgtagc
    18841 tggaaaaacg ttccgctata cagaaaacgg gccagaagga ttagtgacag gtaaaaaagc
    18901 actgcacatc caatctaatg gcggtgtata caacggacaa gactttgcct ctcaatatgt
    18961 aaaaggtatt ttaaactttg taggcatcga tcaagtagat cagctattca tcgaaggaat
    19021 cgattatgac cctgaccgtg cagatgagtt gatgcaaaat gcattagata aagctgctgc
    19081 tttaggtaaa tcattttaaa aattgagata aatgcataca aaagagacag aggaaaaaat
    19141 cttcaaagca gcatttgtac cttggatatt ttcccatctg tctctttttg ttattctttc
    19201 tgctttttca acggattttc ttcataaaga gaagagattg ttgtgtacca ttcaaaaaca
    19261 tgagtaatca ctactttagc tgctgcataa acaggaatcc ccaagatcac accgatgatt
    19321 ccgaacaatt tcccagaagt cagcagaact aataaaatcg ttactggatg gattgctaac
    19381 tgattcccta gtactaatgg agagatcaag cgtccttcta ttgtctgctc tactgcaaaa
    19441 acgatcagta ctttgatgat catgaatgga cctgctacaa tggctaaaaa gatagccgga
    19501 atcatcgcta aaaatgatcc taagtaaggg atcaggttca aaaaacccgc aataatcccc
    19561 aacgtgacag catactctaa accaatgacc gcaaaaccaa tcataaacat gattgccaca
    19621 gcaaaagcca cagttagttg tcctcttata taagaagaaa cttgactatt catttcactc
    19681 agcacattca acgtcggttt ttgcatgcgt gtcggtaaaa atttgacaaa ataaggtgct
    19741 aattgtttac cgtctttcaa tagataaaat aagataaacg gcatcgtcag cagagccact
    19801 aaaatagtcg ctaccgcgcc gacaaaactt ccaagactct gaactgtact cttagatata
    19861 tcttggatca tatcgcctgc cgaattcatg aacttatcac ctgctgtttc caactgttcg
    19921 cgaaattggt tgaacagcgg gtcccgcaaa atctcggtta atttattatc aatcgtatct
    19981 acatattgag ggaagttact gatgaagctc actgtttgtt cctgaatctt agggatgatc
    20041 actacgctcc cccatgcgat tagtgcaaca accaaaacaa acagcccaat gatactgtaa
    20101 agccttggta cttttcgctt ttcaaagtaa tcaactaccg gattcatcaa gtaatacaag
    20161 attcctgcta aaatgatagg cagacctacg attgctaaaa attgccagat tggtgcaaac
    20221 aaatatgaaa cttttgtaaa taaaaagacg atcagcaata ttaacaatac aacaagtaag
    20281 gctgtgacta cttgattatt taaaaaccag cgccaaaacc acgataccgg tctgttcttc
    20341 ttattttttc cttccataat tcctcctgtt agttataaaa aatttggctt cccaaaccaa
    20401 tagcaggcag tctatgcgga tgaagataga ttccatttgc aatttgtcct tcttctggac
    20461 aagcatcaaa aatcaatgat acgtgagcta ctgtctctaa attcccattg gccatcggac
    20521 cgacataatc gatcgtatat acctgatcat caaaagcaat tgttccgcct gctttcaaag
    20581 aaaaaggttc gtcttttgat acttcttgaa tcaccgaata ttttcgtaag gcagctgttg
    20641 ctgttttatc gaacaaaatc agcatgggtt cttccttgtt tattgcttct gtcccaattt
    20701 ctgtaatctt tgcctgaatc attgcactct ctcctttaat tgctttcaaa aacagtataa
    20761 cacattctca ttctttagcc gtgtggaata attatgtgat agaataaaaa cgaaaactat
    20821 ttcattacaa ttaggaggaa tcagctcata tgatcgaaaa gataatttta ggaacctata
    20881 cgcgtcgcga aagtaaagga atctatacga tcgaccttga tacagaaaaa gaagaattag
    20941 ccaacctttc attagctgtt gaagaaaata gccctaccta tgtagcaaaa agtaaagctg
    21001 gcaatcttta cacagttact agtgtggatg gattaggtgg tgccggtgcg tacgataagg
    21061 attttcattt tttgaatgcg gtaacagagt ctggcgctcc tttgtgttat gtagcggttg
    21121 atgaagcacg tcaattacta tacggggcga actatcataa aggtgaagta aatgtctacc
    21181 atatattagg agatggcgaa ctgaaagcag cagattcaat attccatcaa gaagcgacag
    21241 gtcctcataa aaaccaagat catgcgcatg tccactatac ggatctgact cctgaccaac
    21301 gattagtcgt atgtgatctt ggtacagatc gtgtgtatac ttatgatgtg tccgaaaacg
    21361 gcaaattgaa tcttgtaact accttcactg cagagccagg aacaggccct cgccatcttg
    21421 tctttcatcc aaatggacaa ttcgcttatt tatttggtga attagacagc acagtccgcg
    21481 tgctttctta taataaagaa acaggtgctt ttgaagaatt acagaaaata tcgaccttgc
    21541 cagaagaatt cgacggtgaa aatggagggg cagctatccg catttcaaat gatggcaagt
    21601 tcctttatgc ttctaaccga ggacataact cgattgctgt attcgcagtt tttgaagatg
    21661 gttcccacat tcaaaacaag caaatcatct caacagaagg ggattttccc cgcgatttcg
    21721 cactagatcc aagcaataat tttgtcgtgt gtgccaatca gaacaccgat aatctgacat
    21781 tatatcgccg tcatcctgaa acaggattac tggaattact gaaaaaagat gtctatgtac
    21841 cagaatgtgt ctgtgtttat tttgatcgtt agtaagaaaa ggagaatgaa atgaatcagc
    21901 aagacgtatt agacagacta cgggaagaac taaatattcc tttctttgat gggaaaatcg
    21961 aagataaaga gtatagcgaa gaggaatatc agaaactcaa agccgattta cagaactact
    22021 ttgaacaata tgtacagaat gtagaaaact aatcagcttt ccatactatc tgaaaagaac
    22081 atcaggacaa gacttttccg tctatcctga tgttcttttc tacaaataaa aaaccgccga
    22141 gatggttaga ctcgacggaa aaggagtatt tactcgattt tgagtaagta caaggttgtt
    22201 gttggttata ggtatgtcat tatcataaag gattttgatc actctatcat aaaggtaata
    22261 ttacatttat attagataac tctagttttt attgttatca aagatttctt ttattttttc
    22321 aacaacaaat tagtcatttt ttggatggca gctgtcaatt ggtctgtcgc ttggtcttgt
    22381 tttgcttcag atgtattgaa tagatcttca tctacccctg attcaagatc gatactttgg
    22441 atcatttctt cacagcctgc tacatatgaa agataagctt tttcaaaatt tttatgaatg
    22501 cccattgctt ttgctggtgg acgcaaagta ctgactttct taagcattgc ccgatatttt
    22561 tttgttcctt cttcaaataa caggatgatc tcttcaagag tcgatttgtc cagttcactt
    22621 gtttttcctt catcaattgc gtttctgatc acttcatatt tcggatgcat tccttctccg
    22681 attgcttctg tttccttgac gatttgatcg atggactgca cataatagcc aatattcggt
    22741 aacatgttcg ttttcctact ttctccattg ttgttattat ttattctact tgtttttatc
    22801 ctcaaatgac aagtacttga aaaaatttaa tggtttctat acagctcgcc attcttattc
    22861 gtgctcaaag aaaccatctg ctaaactata ttgtttccct gcgacaatgt catattggat
    22921 caattgatat tcgtcgtaaa tctcttgttg cgagcgattg aattgcgctt ctttatacca
    22981 ctgtccgttt tgatagtaca gttctcgttc aaacgccgga agttcctgtt ctaatgataa
    23041 aagcagctga taaaagccat ttgttgtctg attcgtctgt tccattagat tcgctgcaaa
    23101 ataaaacgga ctggtgattg catcgtgagt cgtttgcttt tctaattctc ctttactgtc
    23161 gaacataaga aattgtgttt catgcaatgt ttgtttgtca ttttttgctt ggatcgtatc
    23221 tgaatagatc cctggaagat gatcccccca aaaaacaact aaagtccttc tagaaagatt
    23281 cttcaattct tccgtgaact gcttcagtgc cgtgctgcta taggaaatat cttgcagata
    23341 attctctaag tcaagtgtcc cacttccatc tgaagttttt gcaggatagt ctagattatc
    23401 atactttcca tcgtagggca tatgtgtctg catcgtgact aaatgaatga actgaggtgt
    23461 tttttcttcc ttgagaagtg tcattacttc tttgtaagct gactcatcag aaatatatgg
    23521 attattctct atcgtatccg tataggtcat cgtacgctcg ctgatgaact ggtcaaatcc
    23581 taatgtctga taaacatcct ctcttttata catcgaagta ttgtatggat ggatcgctgt
    23641 cgtctggtat gattgtgcgt ttaacgctga aacgatagaa ggaagctgat ccatttttgg
    23701 tacaagcatc gtgtaagggg tggtgagttg cgcattaaat aacgccatag aaaaaccagt
    23761 caatgcttca aattcgatat ttgctgttcc accgccatag ttttgagaaa gcatattgcc
    23821 actatatgtt tgatcagcta cttcataata atctgccaat ggctcaccag atacttctac
    23881 gccgtttaat cgactaggat ctgagaaact ttcactcatc acgaacacga tgttcggcga
    23941 ctcttcctct acagttttat ttttttcatc ggctagcttc tggtattttt cagtgatttc
    24001 tttgatcttt tctttcgaat atccttcagg ttcatccatt ggttctacct tcagattgta
    24061 caaaaaccca ccgataaaac cagtgttata gtagttcatt ttctggctgt aaggtatcca
    24121 tagtgccgtt ttattatatg cttttcgcaa caaattatcg ggattgttga aattactgat
    24181 ataccctagc agtccaattg ccacaagcag tgtcgttaat cggatcaatt ggaatcgcct
    24241 tccttttttc aggcttcgaa acatgtacca gcaaaacaat cctatcacgg ttcctgcggc
    24301 agctaagatc actgtaaaca gcatagtgcc ggtcatatct ttcagcaatc cgatttcagt
    24361 gatcatcttc aaatcgtctg gataaatcgg ttcttgccga taactcattt tcatataatt
    24421 tgcaaaacct aatacaccga tggctacgac atacgtaagg gaacctaaag ggacagatcc
    24481 tgctagtgca atcagaaaaa taagaataat cagcaagacg agacaggcta agaagaattt
    24541 ttccgtatgc caagaaaaag caaatttcaa cgcaaggtct acggatagat cattttgaca
    24601 ccactgcaaa aataaattac taaaaacaac aagaaaaaag atactgatga ttgctgctgt
    24661 tccttttaaa atctttttct gtttggtcga aagtctgctt atatatcttt tcaaatgctt
    24721 gctccttcat ttctatcaat aaaagaatgt tgcttctctt attttagttg tacgaaattc
    24781 gaaagtaaag aacggaaaga agaattaatg aaatccaaat attctctttc tttatggcct
    24841 ttctggtttc tttaataagc ggacctttcg tactccagaa attttttcta gctgttgttt
    24901 cacttgattg agctgttcaa aatcagtact gtctatgtca atcaatatgt agacatgctc
    24961 attcttatgg ttacgcgata tatctgcgat cgctagctcg ttctcattca gcagagaaaa
    25021 tatctctgct aatatattgg ttttcttttg ataaaatata gtgaatcgaa acggcgcttg
    25081 gaaaaacatt cgtgcggatg gataattgac cgcttctcta accgtaccga acaaaagata
    25141 atcttttaag gcttcaactg ccaaacgtcc gctgtctgcc aaagcttcct gagtcgatcc
    25201 ccctagatga ggcaacataa gtatacggtc attttctaag aactcttctt ctggaaaatc
    25261 agtcaagtat ttagccagat gttgtttttc caatgcttgc ataacagcat atttatcaac
    25321 aatttcactt cttcctacat tgataagtac agcatctttt ttcatttttt ctatattcgc
    25381 ctgatcgatc aatccttttg tatcttctgt caacggcagc atgactacga tgtaatccga
    25441 ggtagaaaga actgtttcta aatctgcttg ccgaacataa tccaactggg catcgcggat
    25501 agaataaccc aagacatcca tccctaagct atagcaactt agcgctactt ttgtgcctat
    25561 cgctccaaga ccaagaagac cgatggtttt gccttgcaat tctcgtccca cataagcact
    25621 tcttttgttt tctgcctgtt ctaaaatatt aggacctgtt agtgtttgta ccatacgact
    25681 tgcttcgatt atcggacggg aagataagag caaacagcac aaaacaagct cttttactgc
    25741 attagcattt acacctggtg tattcatgac gatcgtcccg ttttcagaag ctttttcaac
    25801 gttgatcgtg ttcaccccaa caccagctct tgaaattgct agcaaatctg gtgtaagcca
    25861 ttcatctttc actttcgtac tacgaataac tattccttcg gctggcaaat catctattat
    25921 tttgaaatat tccccttgta acttttctat ctcttgttct ggaatagcat caatcaaatg
    25981 aacgtgatac ataaaacccc ctccttacta acaagtatct cgaaatttct gcaattagac
    26041 aactgtttac catttgactt cctagaagca aaaagagcag ttagagcaga gtaggctgag
    26101 tgataaaaat aaggctatga caagttactg ccataagcct tattttcgag agcaaaatat
    26161 tgagggtgag atatcttgat aaatggtgtt ccgttagctg acattgataa taagactaaa
    26221 tttcaaaaaa gttgaaaagc aaatttcgtc aatctcttct tatttcttaa aactaagtgg
    26281 ctttttcaca acctcttttt atctaataac cactgtttcc aactcaacta attttgccca
    26341 cgtttcaatt tgatctgttg ttagatttag cgagacaacg gtatgatgac cgccacctgc
    26401 ctgaatccat gaatggacac cttcatggaa attcggttta gttttccata acacacgtgc
    26461 aacaggtaaa ttaggtgctt cagtcgttgg ttcaaaggct tctacttcat tgatcagcag
    26521 tttataatgc gtaccgaaat ctgccatcga tacgactacc ccttctcctg ctttcccatc
    26581 aaatacaaga cgcgccggat cttctctatc tcccattgat aaaggagaaa caacgattct
    26641 tggtttcgtc gcagcaagcg tcggatctac ttccatcata tgggattcca agattgcttc
    26701 ttggccacta gctagctcgt aagtataatc ttccatgaat cctgtatctt tccctcgagc
    26761 catgattttc agcaaccgat caatcgctgc agttttccag tcgccttccc cagcaaaacc
    26821 gtatccttct gccatcaaac gttgtacagc tagtccaggt agttgtttca ttccatacag
    26881 gtcttcaaaa ttagtcgtaa aagcgttata gcctccttct tctaagaaac ggcgaatacc
    26941 gatttcctgc tgagcttgta cttttacatg ttcctcccat gtcttttctt cataatcacc
    27001 atagtcgaag gtatacaatt ccttgtactc ttcaaataat tgatcgactt cttcgtctga
    27061 tacgcgatcg attacttgta caagatctcc gataccaaaa taatcaacag tccaaccaaa
    27121 ttgaatctgt gcttccactt tgtctccttc tgtgacaccc acgtttctca tgttgtcacc
    27181 aaaacgagcc acttttattc caaaactttc attataggct actgcaacat ccatccaatc
    27241 agcaatctct ttttggatct caggtcgttt ccagtagcca acgacgattt tattttgttt
    27301 atttaatcga gcattgatga acccatattc gcggtcacca tgagcggatt gatttaaatt
    27361 catgaaatcc atatcgatcg ttttccaagg aatgctttcg ttatattgcg tagctaaatg
    27421 aagcaatggt ttttgtagaa gctttgtccc gcggatccac atttttgctg gtgagaaagt
    27481 atgcatccaa gtgatcacac ctgctacttc ttctcgataa ttgacctctt tcatgatttt
    27541 tgtgatcgta tcagcagtaa ctgctaattc ttgaaggcgg attggataag gcaattggcc
    27601 attttcattc agttcatcga ccatttcttg tgcatgtttc tttacttctc gcagtgcttc
    27661 ttccccatat aaatgctgtg atcctacaac aaaccaaaat tctttttctc caatattcaa
    27721 cataattagc cactcctttt atttgttttg tccgtaatac gcattttttc cgtgttttcg
    27781 taaataatgt ttatctaaaa tccgttgagg cagctcttct gaaaatgaat tgagctgtct
    27841 ggtaaataaa ttcatcttgc atacttcatc tagtacgact gcgttcatta ccgcactttg
    27901 cgcatctttc ccccaagtaa atggaccgtg tccgtgtaaa agtacccctg gaattgctaa
    27961 gggatcaatt ttgcgttctt tgaatgtttc tatgataact tttcctgttt catattcgta
    28021 cccgctgtcg atttcctgtt gtgtcaaaaa tcgagcacaa ggtaccgatc cataaaaagt
    28081 atctgcatgc gtcgtcccca tcgcaggaac atccaatcct gcttgtgccc agatcgtcgc
    28141 ccatgtcgag tgagtatgga cgattcctcc gatttgagga aatgaacgat ataaaacagc
    28201 atgagtaggc gtatccgaag agggattgag tttaccttca atgatatgat tgtccaagtc
    28261 cacaacgacc atgtcgtctg ctgtcatctc ttcataactg actccgctag gtttgataac
    28321 gaaatatcgt gtttcaggat caaaagcgct cacatttccc catgtatatt tgacgagtcc
    28381 gtgtttaggc aagtcaagat ttgcttggta tacttcttct ttcagttgtt ccagcatttt
    28441 ctatcactcc tttttcttgc aattgatgaa tcgctgtttt ttcaatgtcg atcccctcac
    28501 ggtaacgtct cataaatatc tgatagcctg ctatttcttc tgctgaaggt gtgatggtga
    28561 ttccttggtc ttgtccaaac acgtcttctg ccaagaagtt ttctaaagac ttcccatgtc
    28621 gatccatcat ataggctgct aataacgcga ttccccacgc tccaccttct ccggctgtgt
    28681 ccatcactgt aactggtgcc tccatagcag atgctagaat ccgctgtcca acttctggtg
    28741 ttttaaaaat ccccccatgc cccactaaac gatcaatttg gacattctca gatttcaata
    28801 tatccattcc gattctcatt gcaccaaaag cactggctaa atggatccgc atgaaattcg
    28861 ctaaatcaaa acggctacct ggtgtacgta caaataatgg ccttccttca tttactcctg
    28921 taatgttttc accggaaaaa taaccataag aaagtaatcc cccgcaatcc gtatcgcctt
    28981 ctagcgcttt gttgaataat accgtgaata atttatctct gcttatctcc atacccaaag
    29041 aattggtaaa ttcttcaaaa atactgaccc aagcattgat atccgaagag cagttattcg
    29101 tatgaaccat gcctactagt tctcctgaag gtgtagtgac catgtcgatt tccggatgga
    29161 cattttctag ttctttttct aatacgatca tagcgaaggc ggaagtacca gccgaaatgt
    29221 tccctgtccg tttggctaca ctgttcgtag cgaccatacc ggttcctgca tccccttctg
    29281 gcggacaaac cgggattcct ggtctcaaat ttcccgtagg gtcgatcaga taagcccctg
    29341 attcgcttaa cttgccagct tcttctcctg ctactagaac tttaggcaaa atgtgatcca
    29401 agtcaatcgc tacgtgcgct ttttcgatta actgaccaaa aatatttttc atttcttgat
    29461 ggtaggtttt cgttgaagga tcgataggaa acatgcctga tgcatctcct acgcctagta
    29521 ctttctcacc agtaagctgc caatggacat aacctgcaag cgttgtcaaa aaattaattt
    29581 ctttcacatg ttcttcttta ttcaaaatag attgatacaa atgagcgata ctccatctct
    29641 gcggaatatt gtattgaaat ttttccgtta atattcgttc tgcttcttca gtgattgtat
    29701 ttcgccaagt acgaaatggt actagtaact gttccttgct atcaaatgct agataaccgt
    29761 gcatcattgc actgaaccca atcgacccga ttgtcgtaag attctcgcca tagatttcga
    29821 atacttctgc tgccattttt cggtaactga cgcgcagtcc tttccaaata tcttctaatg
    29881 aataggtcca gataccattt tctagtttgt tttcccactc ataactacca gcggcaatag
    29941 gagtaaaaga tgaatcaatc aatacagctt tgatcctagt tgatccaaac tcaatcccta
    30001 aagatgtacg accatctatg acatctaaca tactttgcgc atttacttcc ttcataatga
    30061 tttaactccc tccttctcgt caaacctgat caaaccgtct ttttagtagc gcttacaatg
    30121 attattgtat acttttgtac gtacatgtca agcggttatt tacaagaata caataaaaaa
    30181 cacttgtttt gtacgtacat aagttataaa atgaaattgc ttacaaaatc tgatcaaccg
    30241 ccttctcgaa attctagaag gagagaatac ttatgaaaaa agaaaaaaaa gtttcctcat
    30301 cgtttattta tttttttggc gcatttggcg gcattctatt tggatatgat attggtgtta
    30361 tgaccggcgc cttacctttt ttacagcatg attggggttt ggcaggtaaa gcttctttga
    30421 taggatggat cacgtcttcg gtcatgttag gtgcgatcct tggcggctct ttatctggtc
    30481 ttctttctga taagcttgga cgacgaaaaa tgattcttct ttctgcactt atttttatgg
    30541 ctggttctgt cctttctgca tctgcccctc acaatggttc ttattttctg attgcagcaa
    30601 ggattcttct aggtttagct gttggcgctg catctgccct agttcctgct tatatgtctg
    30661 aaatggctcc tgctagacta aggggaagat tgtcagggat caatcaagtg atgattgctt
    30721 ctggcatgct cctttcctat gttgcagatt atttgctaaa agtgttgcct gaaacgatgg
    30781 cttggcgcgt gatgttaggg ctcgctgctg tccccgcgct gattttattt ttcggtgttt
    30841 tagctctacc agagtcaccg cgttttctta tgcaatctgg ccgcttggaa gaggcaaaaa
    30901 gagtattgaa ctatattcgg acaccaaaag aagctgaaca ggaattcgaa caaatccagc
    30961 tgaatgtcaa acaagaaaag acaaccggaa cttcttggca tactttgttt ttagaaaaat
    31021 atcgttcctt agtcattgcc ggtattggtg tagcagtatt ccagcaattt caaggagcta
    31081 atgctatttt ttactatatt ccgctgatcg tagaaaaagc gactgggcat gcagcgagcg
    31141 atgcattgat gtggccgatc atccaaggaa tcattttagt tgctggttct ttgctctttt
    31201 tggttattgc agacaagttc aatcggcgaa ctttattgaa aataggcggt agcgtgatgg
    31261 gactttcatt catcctacca gctgttttag gaactgtact ggatgctcat acaaattcgt
    31321 tgttgattct cttgttttta tgtatttatg tcgcatttta ttcttgcaca tgggctccac
    31381 tgacatgggt aatcataggc gaaatattcc cactagctgt ccgcgggcga gcatctggcc
    31441 tagcctcttc ttttaattgg attggttctt tcctagttgg cttgcttttt cctgtgatga
    31501 ctgcttctat gtctcaagaa atcgttttcg gcatttttgg gatcatctgc tttttagggg
    31561 ttttatttat tcaagagatc gtaccagaaa ctcgtgggaa atctttagag gaaatcgaac
    31621 aaagtgcatc taaaaaaact tatcctaaac gtatttctat ccatcattct taaagaggtt
    31681 gtgacagaag tggtcagctt caagaaataa gaaggaaccg cttagtttcc agtcacaagg
    31741 aacaatttca aaaaacagct tctcatgttt gatgaatatt gtgacttgtg accagttggt
    31801 aggagaacac cgtttagtgg agaggtggtg aaagaaacgt tcagccttga gcgatgacaa
    31861 aagctctcac aaacattgcg acgagtaacc gtaggagcaa taagaggcgg taaaaacccg
    31921 tctcttattt ttcgttttct ttcactgttt cccgttcaac tagtacaggt tcatagagaa
    31981 tatttggctg tgcctgtcct ttttcaatcg ttgtgacgat ccaccgtgcg gcatcttgtc
    32041 ccaacttttc ttttggatgc gtcaatgttg tcaatttttt attccctaaa tggcttaaag
    32101 aagaatcgtc tgttcctacg atcgataggt catctggaat atgatagcca ttttctgtca
    32161 acttatctag cattaaacta gctatttgat cgttatagca aatgatgcca tctaaagctt
    32221 gttcttcttt caaccgttgt actgtttttt cagcgattgt ttctcgtgtt tccgtggtga
    32281 aagtaatgat atcttccgtc aaaaaacgca cattatactg ttcacacgcg ctgataaaac
    32341 ctttcatcct gtattttcct tgaagatcgt cgatttttgt gatgaacaac agacgctgat
    32401 gtcctttttt tatcaaatat tctgctgcca taaaaccgac tttcacatca tctaaacaaa
    32461 tataagaggc atttaactct tcataagcag cattgatcat caccatcgga atgccttgtt
    32521 ctctcaaagc aacataaagt gctaagtttg ggttatactg attacttttc gtaggctcaa
    32581 cgatcaaacc atctacccca taagcaatca ttttcttcaa acactctttc tccaattcgt
    32641 gatcgttatt cgtactggct aaaagcaatg aatacccaga ttctcgtaat tcattttcga
    32701 ttcctcggat aatcgacgga aaaatataat cagagagata tgtggtgatg acaccgatcg
    32761 tttttgttct gttcaatggt gttttttctt tcttatagct gtcatctaca tatgtgcccg
    32821 accctttttc tttacgcaga tagccctcat ttaccaacac agcgattgct tgccgaatcg
    32881 tatgtctgct gacgtcatat atttcttgca gcttgaattc tgagggaatg gttgtattta
    32941 cttcgtattc ctcacgaagg atcttttgtt ttatctcttc tgcaatatct tgatattttg
    33001 ccatttgcct tgcccctttt tatttgtacg tacatatatc ataacgagtc tgcaaggttt
    33061 attcaagcaa aaatcaaggt ttcttgtgct cataaggcat acggaacagg ttcaccaaat
    33121 tctggaaatc cttgctcatt ccacgtaaag cattgcgcgt tcgcgtgccg attaggattg
    33181 tctaacggat cccctttttg gttcttctct ggtcgagcat gatagatcaa aatatcaaag
    33241 cacccgtctt ctgaaaccgt aaacgagttg tgaccaggac caaattgctt atttttttca
    33301 gaagaaacga atactggctc cgataattta tgccatgatt cttttaataa aagattcttg
    33361 tgctcatcag cccacagcag gcccatggca tagttttcat ctgttgcact accagaatac
    33421 gtaatgaata ttttcccatt gcgagtaagg actgctggac cttcatttac tgaaaaaccc
    33481 cgtttttccc attcatactc aggtatagaa aggaggatct gcttcccctt taacgtccaa
    33541 ggattatcca tttcggatag ataaagatta gaattcccag taatttcagg atcttgttgg
    33601 gcccacacat aatatagctt tccttgagaa gagaaagttg ttccgtctaa actgaaagtt
    33661 tcccttttcg tttttatttg tcccttttct atccaatctg tattcattgg atctatatgc
    33721 tgattttcaa gtacgaacat gcggtgatga tgagattcat cacgtatagt tttatgattg
    33781 cttgcagcaa agtaaatata ccattttcca ttgatataat ggacttcagg tgcccagatc
    33841 aattcactca tcggtccttc ttcatgagcc tgccatacaa tcaggcttgc agcatgttct
    33901 aattcattca gtgactttgc ccttcttaat tcaatcactt ggtagcctgg aaccgatcct
    33961 gtaaaataat aataaccatc tgtatgttta tatacccaag gatctgcccg ttgccgaacg
    34021 ataggattat tataaagtgt cttcatcata acaaatttcc tcacattttc tttattctaa
    34081 ttacattcca agagtatttt tctatcccta catttaattc gtcatgtttt tctattgaaa
    34141 aatagtttat ttcaggtttt attttttctg gttcttcacg tgtatttttg tccaacagat
    34201 cgctactggt taatgtgtag tgctctcctt gatctagcaa attgaaatca tgttcaatcg
    34261 ttatcttttg ttgttcattt gtgcgattga tcaagaaaat agtcagctga ttgccgttat
    34321 ctacgatcac actgtccaca taaggaacat tttttatctt ttcacaatca taaacagggc
    34381 aaatgatttg ttgtttcaat acttgacctt tagcatattt cgataagtgt tgcatcacat
    34441 aataagttgg attcctccat gcttgtcctt tagcatctgt cagtattaaa ggtattgtgt
    34501 ttactaacaa tgattgacaa ctaatcttta cgcgatctgc gtgtcgtaaa atagccagcc
    34561 ctaatgaacc aaataataat gtatcttcca tagtaaagta acaccaatcg atgggactac
    34621 cgacttcaaa atccctatgt cttttttccg gttgggcatg tacattccat tcatcaaacg
    34681 ctagatacat tgttttctca cttctcaaat atccttttac ataatcacaa gtagcaacga
    34741 tttcttcaat ttgacgatcg aatcgataag cttttgcaag gtatgtcgct gtatcatcac
    34801 gctcattttt aggaggttta gtcaagtctt cttcatcata cttatcaata tagttatgca
    34861 aagctaaata atctacattc tcataagctt cttctaatgc gatacgatcc cattcagggt
    34921 acgatggtaa acgtggcgta gagcttccaa ctaagattgt ttcaattgaa tcatccacta
    34981 acttcatgac ttttgaggct tcatttgcta acctaccata ttcataagca ctcttagccc
    35041 ccacttgcca tggaccgtct agctcattcc ctaaacacca taatttaacg ccaaaaggct
    35101 ttttttgccc attttttatt cttaaatcac tccagaaggt tccttttgga aaattacaat
    35161 attctactaa attttttgct tcatcaattc cttttgttcc taaattcacc gtgaatatcg
    35221 gtttcgcttg tacatgactg atccatttaa aaaattcgtg gagtccaaaa gaatttggtt
    35281 ctatacctcg ccatgctaaa tcaatttttt ttggtcgttg ttctttccta cctacagtat
    35341 ccacccaatc ataaccagat gtaaagtttc ctccaggata gcgaatgaca cctaattcta
    35401 attcctttac ataagagagg acatcttgtc taaacccgtc accatcagct gtttcatggc
    35461 ccggttcata aatccctgta tagacgacac ttcccatatg ctcaacaaat gagccaaaca
    35521 gccgagaact gatctctcct accgtaaaat cctctctgat ttttactttc acttcttcgt
    35581 ccaacagctt tccctacctt tcatttccta tagtcaagat aatagataca agtttccata
    35641 cgccaccagc aaagataaaa ataaaaggag ggaaaagaaa tatgagcagt acaaatccta
    35701 ataacaatac gcaacaaaga atatttctca aaaaatcaaa aaatactttc catgcacttt
    35761 gttcaaaaat ttgtaaaaat gtgatatctt tgttttcaga aatcacatat atccaggata
    35821 aaagaaacat ggaataaata agtaaaacta catatccact aattgaaagt acgattgtct
    35881 gttcttctaa taattgatta acaagaaaat aaataatgat cgttaacaga ctaaggaaca
    35941 agttcttacc aaaatgttgc tttattcctt gaaagaaaaa ataaatgata tttcctgatc
    36001 cctcaccttt ccattgcgcc attacataaa aaacagcaca tgtagcaggc acgatagtaa
    36061 taacaggcaa acacacgatt acccagagaa tacctaataa gatgtaatca gaaaccacaa
    36121 tcaactgtcc ataaaattta gtctcaacta ttttcatctt cctcactctt tcattccaga
    36181 catagctgtt ccttgaacaa aatatttctg tgcaaaaata taaaccacta gtaatggcag
    36241 cattgaaata accgttccag ccattacagg tccataaaaa gaaatgttct gccctgtaaa
    36301 taaagctaac cctgctggta aagttctcat ttttgaacta cttgtcaata tcaatggata
    36361 aagcaagtca ttccaactat tcatcagcgt gaaaatccct aatgataaaa gagtaggttt
    36421 gctcaatggc aacatgattt tcaaaaaaat attaaactca cttaatccat caatgcgtgc
    36481 tgcctcttcc aaagaatctg gtaaagtaat aaaaaaggaa cgcatcatga agataccaaa
    36541 tgcagttgtc atacgaggaa tgatcaaacc tgcataagta tcaagcatgc caagcaaatt
    36601 gacttcaata aatagaggaa tcatgaagac ttggaatggg atcatcattg tcagcaaaac
    36661 gaaatagaac aaaactgatt ttcctttgaa acgcatacga gcaaatgcat accccgcaag
    36721 agaatcaaag aatacagaag tgatcactgt ccctccagca aaaatcactg tatttttgat
    36781 gtaatctaat aaagggatcg ttgtccaaac cttaatatag ttatctaggg tatagctatc
    36841 tgcaaatatt ctaggcggaa atgagataat gtctttttcg tgtttaaaag aagaaataat
    36901 cagccacaaa aaaggaaacg caataaccaa caatataact agcatactaa tcgttcgaat
    36961 gattttttta ccactaactg cttttcgact attcacagta actgtaatcg agctttctgg
    37021 tgccatacag gtttccctcc tatttcattt gtttttcttt ccgtgacatg tacacattag
    37081 tggagatagc tatagttgca acaatgataa acaaaaccga agacagtgct gatgcatagc
    37141 ccaattcata aggtgctgta aatcctcgac tgtaaatata ttgaacagct gtttctgtct
    37201 taaattgtgg gccaccagcg gttgcaacat atacttggtc aaacacttgc atcgaaccaa
    37261 tcagattcgt taaaatacaa aaacctaagg agggaacgat ctgaggtagc gtaatgttaa
    37321 aaaactgctg tcgatttgtt gcaccatcca tttgagcaga ttcatacaaa gagggagaga
    37381 ttccctgaat agcagtcaag agaatcgtca tagtaacacc aaaattcttc caaacagtca
    37441 tgatggctac cgtcggcata gcaagggttg gatcgcgaaa aaattgaggg atcggcaagc
    37501 cgacttgtga aaacaagtaa ggaatcgccc ctacattcgg atcaagcaac atagaaaaaa
    37561 taatcgcaat tgacgtcaat gaacaaataa ctggaatgta aaatgtcgaa cgacaaaaac
    37621 gattgaatct ggtattttta gataatgcta ctgctgctaa taaaccaacg ataatttgtg
    37681 ttggcgtttc gagtacggtg aaatataaag aatgaatcaa cgaattaact gctcgttcat
    37741 cactaaatat acgtgtgaaa ttttcaaaac ttacaaaatt tcttgatgta aagaaaatat
    37801 tcaaatctgt aaaactaata gcaaatgttc ctaaaagcgg tatgacagta aataataata
    37861 aaactaaaaa agatggagtt aaaaacaaat acgcagcacg atcaggacga ttccaatatt
    37921 tggtgaatcc gttcatatag tccacctcat ctttcatttt gataaaatat acaatcttgg
    37981 tttaaacgaa tctgaataag atatccgaac aatcgctgtg atttttgcaa taacacctat
    38041 ctgcaaatac taggtcgatc attcagatat ctgtatcttg ccaacagtct atcctgtata
    38101 aagttctgta ctatttttgc agtaattgat tgatggcatc atctgcatcg ttcatgagtg
    38161 tctcaggatc ttctcctgct aataattttt caatcagtgg attgatgata tcgttattga
    38221 tcgcagagat ttgggtaaaa cctggtaaat atggctctgc atagtccatt tgtttcgata
    38281 attcagatac aataggatca ttttttactt cttcatcttt tgctactgaa tccaagtagg
    38341 caggaaaacc attttcgata ctccattttt taccaatttc agttgtattc caatatttca
    38401 aaaactcata gacagcttct tttttattat tatctgtact tgccggaatg gcatatccta
    38461 cgccatctaa aatagctgtt tttttgtctg aatcactccc ttgtggtaag gtagtcacat
    38521 tataatcaat ctcgtttgct ttcaatccgt tatttaacca tggcccattg atttcaatgg
    38581 ctagttgacc agcattcatt aaattgtcca tttcggcgcc agaaatcgat tctggaccag
    38641 tcttgtctac atggatcatt ttttggatcg cttttaacgt tttaaggttc tcaggagacg
    38701 caaattcaga cttagtataa tcatcgttca ctaatttacc gccatttgct aacatccagt
    38761 tatataacgg tgcagttcca tccttattga agacaaaacc tgatacattt ttactactat
    38821 cagttaattt tggtgccatt tctgtcaatt cttcccaagt agtaggtggt tgttcagtat
    38881 ctaatccagc ttgtttaaac aaatcattat tccaatacat atacatgcct tgtacctgca
    38941 tggggacaaa atactgttta ccttctactt cacctaattc aatagccgtt tctttaaaat
    39001 cagatttatc tactccatca tattcccaga aatcgtctaa tggttgtacc gctccgtttt
    39061 ctacatactg tgcaaaatct ggataattta atgcaataaa gtcaggtgct tttttagaag
    39121 aaatcgctgt aggaagtttt tcattcaaat tggcccaagt catgatatcc atttcaattt
    39181 tgatgttttt atcatttgtt ttattaaatt cattaacgat ttcttgcaat atttcaccat
    39241 cagatgcagt aaacccattc caaaaagtca aagtcacttc tttatcagaa tcagattctg
    39301 ctgaacttcc gccaccgcaa gctcctaaaa tacctgttgc agctaccaac aaagagccaa
    39361 ttaaccattt tttacctttc attttttgtt cctccttcat ctgataaacg acatctgacc
    39421 acattccaag atagcggttt caataaacaa ttgattttcc catcttcagc ttttacattt
    39481 gttgaatgac ttggttttac ttgttcactt ttaggaagat tagttgcttt tgtatcaaat
    39541 ccactcattt cagaaaaatc aatcactccc tctaatgata attcagacaa gtgaacagtt
    39601 agattcattt cttcttctcc acggttaact gcaaatatga caagttcttt gtcatttatt
    39661 acggctatac tttctaaata cggcacttct tcaaaatctt ccgtcgcata gtttgctgaa
    39721 cgaatttgtg ggcttaacac ctctccttgt ccatacacag cagcttgcat aaatggataa
    39781 tagatcgtct gtctccaagc ttctccgttt gtttctgtcc tgattggtgc aataacgttt
    39841 accaattgag caagacaagc aatctttact ctatctgcat gtttcaataa agtgattaat
    39901 agacagccta atagtaatgc atcttcaaaa ttatagttat cttctagtaa aggaggagca
    39961 atctgccaag gcgctgcttg ctcatcttgt tccgctgaat gataccaaat attccattca
    40021 tcaaaggaca ggttgatctg cttcttacta tgtttcttcg ccttgactgt atcgcacatc
    40081 gctgtcactt cagaaatgaa ccgatccatg tctaaggaac gtgcaagata atgagaaaga
    40141 tcattttttt ggttgccata atattgatgc agagacaaat aatctatttg atcgtacgct
    40201 tgatcaagaa ctgttaactc ccaatcacca aatgtaggca tttgccgatt cgaacttccg
    40261 cataaaacca cctcaattga atcatctacg agtttcatcg ccttagccgt ttcctctgct
    40321 aaccgtccat attcttccgc tgttttatgt ccaatctgcc aaggaccgtc catttcattc
    40381 cctaaacacc atgtcttaat tccaaaaggg ctctcttgac cattcgaacg ccttaaatca
    40441 ctccaataag ttcctttagg aaaattacaa tattcgacta aattacgagc tgcatctact
    40501 ccacgagtac ccagattgac agccatattg atttcggccc ccacatgctg acaccagtta
    40561 taaaattcat gaatcccaac ttcattcgtt tcaattgtcc gccaagctaa atccaacctt
    40621 ctaggtctat ttgctatggg cccaatactg tcttcccaac gaaatcctga cacaaaattt
    40681 ccaccaggat atctaatcat gggaatgttc aattctttta ccaagtgaat gacgtcttgg
    40741 cgaaatccac ttttattagc tgatggatga tctggctgat aaatcccttc atatactgct
    40801 cgtcccatat gttcaataaa tgaactgtac aaccgcggat caactttgcc tacacgcttg
    40861 acactactaa tcaacattgt ggcttccata actgacctcc tttaatttat acatgaataa
    40921 tacacctcgt tgaaagcgtt gtcaataata taaatgttaa acttacttat tttttatcga
    40981 ttttaattaa ccaaaatatt aataatgatt aaaacaaata atttaatata acttttatta
    41041 acaaatatgt taatatataa gaaaaacctt ttaagaggtg atatatatgc aactacaaat
    41101 aaacgaagaa tccttaccgg tatatgaagc attagctagt aaaacaagga tcaagatcat
    41161 ccagctactt tccaaaaaaa agatgaatgt caaagatttg gcaaaagaac ttggagtgag
    41221 cagtgctatc acgacgatgc acgtgaaaaa gctagaggaa gcaaacatca tcaaaacaga
    41281 aaaagtagga caacaaaaaa tttcgagcct tcgtgtcgat aaaatcgata ttagttttcc
    41341 agaaaaaata ttcaatgctt ttgatacgaa agaaacatcg atacctattg gtcactatac
    41401 aaattatgca attgaaccaa catgcggttt agctacgatc catgatttta tcgggaaagt
    41461 ggatgaacca cgctatttta tggatcctcg aaggatggat gcccgcattc tctggtttac
    41521 cagcggattt gtcgagtatc aggcacctaa ttttttaaat acagaggata cattggagat
    41581 gttggaagtt tctgtggaaa tttcttctga atttcctttt tcaaatgaca attggccttc
    41641 agatatcact ttcagcctaa atggtgtgga gctaggaaca tggacgagcc ctggagattt
    41701 tgctgatatc cgcggtaaat atacgcctga ttggtatcca gataatctta atcaatacgg
    41761 cttgctgaag acgatccgaa ttaccaaaca cttgacgaat atgaatggag aacccttgtc
    41821 aaacatcacg atcaacgaca tccctaaaga gcaagacact tggcatttgc gaatcgaagt
    41881 gaaagacgat gccaaacatg tggggggctg tactttattt ggtaaaggat tcggtaatta
    41941 cgatcaggat atcaaattaa aagtttacta cagctgatat ttttcttttc tattttataa
    42001 aacaaaaaca gccaatccct atgaagggac ggctgttttt gctttattgt tatttccaga
    42061 aatcatccaa aacggaaatt ggcaaatgtc gtttatgttg tgtcttgttc caccatgctt
    42121 cgattttttc ttgtgcttga gcgggaactt cttttccttc tagataatca tcaatttcat
    42181 tatatgtgac acctagtgcg acttcatctg caatcattgg tttcccatct tcaagatctg
    42241 cagtcggaat ttttgtgtat aatttttccg gtgcattcaa tgcttgaagc aattgtttcc
    42301 cttgtcgttt gtccaaacgg aataatggca aaatgtcggc tccaccatca ccaaatttcg
    42361 tgaagaatcc agtaatgttt tctgcagcat gatctgtccc taatacggct cctgctcttt
    42421 ctccagctac ggcatattgc gtaatcatac gttgacgtgc tttgatattt cctttgttaa
    42481 aatcgctgat tcccacacct gcttcgctta atacttgtac ttgtgcatca acagctggtt
    42541 tgatatttac tcgcagacta acatcgggct ggataaagtc aagagcagct tttgcatctt
    42601 cttcatctgc ttgttcacca taaggaagac gaacagcgat aaattgatag ttttcatctt
    42661 ttgtttcttc acgcatttct tccatcgtta gttgcgccaa acggcctgct aaagtagaat
    42721 cttggccgcc gctgatacct agtacaaaag ttttaagaaa cggatatttt ttcaaatatg
    42781 ctttcataaa gtcaatactt ttacgtattt cttcttttgg atcaattgtt ggtttgacac
    42841 ctaattcatt gataatttct gtctgcaggc tcatttattc tcctcctatg cttctgtatg
    42901 aagttctgct acgctttttt tcattcgttc catgatagcc attttatggt tccagcattc
    42961 agtagacaga tcgactgggt atttttgcgg attcaagtct cgtttatact cttcccatag
    43021 tgaatctaga ttttcttttg tatattcttt gatttcgttt agtgcaggta attcgtaaac
    43081 tctttttcct tcgataaaga tatcttgtaa aactgggcga gctgtaaagt ctcgaacagt
    43141 tttattgata aacgtatgca ctggatggaa catgaagata gcttcttctt ctcgagggtc
    43201 ttcatcccat aatgtcacgt agtctccttc agatttccca tcaaaatttc gagtgatgcg
    43261 ccacacttgt tttttccctg gagtagttac tttttctgca ttgcttgata acttgatcgt
    43321 atccatcatt tttccttcat catcttcgat cgatactagc ttgaatactg caccaagggc
    43381 tggctgatca taggctgtga tcaattttgt cccaacaccc catacatcaa ttttagcttt
    43441 ttgcatcttt aaattcaaaa tcgttgcttc atccaagtca ttcgaagcat agatttttgc
    43501 ttccgtaaat ccggctgcat ctaattgttc ccgaacacgc ttagatatat aggccatatc
    43561 tccactgtcg atgcgtacgc cttggaagtt gattttgtca cctaattctt tcgccacgcg
    43621 aatcgcactt ggcacacctg atttcaacgt atcataagtg tcgactaaga acacgcagtc
    43681 tttatgggtt ttagcgtagg ccataaatgc ttcataatca tttccataag attggactaa
    43741 cgaatgagca tgggtcccgc tagctggtat cccaaatatc ttcccagcac gtacattgct
    43801 tgttgcatct gctccgccga tatatgccgc tctagttccc cagactgctg catccagttc
    43861 ttgtgcccgt ctagttccaa attccaatag tggatcttct ccgatgacag atttgatacg
    43921 agctgctttt gtcgcgatca acgtttggaa attgaccata ttcaacagtg ctgtttctac
    43981 taattggcag tgcgctaaag gcccttccac ttggatcaat ggttcatttg caaaaactag
    44041 ttctccttca cgagcagaac gaactgttgc tttaaattca aaattttgta aatactccaa
    44101 aaaaccttca ggatagactt ctaatccacg caagtaagca atatcggaat cattgaacgt
    44161 cagattctct aaataattga ctaaccgttc caatcctgca aaaaccgcgt atccgtggtt
    44221 aaaaggcatt tctcgaaagt aacattcaaa aacagcatgt aaatcagctc gacctaattc
    44281 ccagtatgtc tgcatcatat tgatttgata tagatccgta tgcagcgtca aactgtcgtc
    44341 tgggtaagta ttattcatct tgtattactc ctcttggcaa gttttcattt cctacccatt
    44401 ataacaaaaa aaattaatag gaaaagaaat cttccatttt ttctgaaaaa gcacatgttt
    44461 tacggatatt tcttgctaaa aatgaactcc atctgctaaa actatccttt cttattggta
    44521 tttaacctaa acgagaaaga atacttattt tattcaatgt atccgagaca cgaagaaatt
    44581 agcgttttct atttttctta cttgataaaa taagtagatt ttcctactac aatcgtagcc
    44641 gttaagatac cgatgattga acaaatataa ccaaatgtct ctacaacata atcaatggca
    44701 aaagtttttg aagcaataat acgtctttcc ttttttgctt cttatcccca aagaaacgga
    44761 tataacttat tatgtattga atttttttgg aaaggcgaat tatgacaaga tataccttgc
    44821 gttgaaaaaa ctcgcggaaa aaatatcaca cgtttttaaa aagatacaaa gtaagaaagc
    44881 agctgtcaat agaatggaaa caaaaatggc gagacatcaa tcagtctcgc cttgtttttt
    44941 attgtataca ttagatatgg agcaggttac cataaagatg attattagtc gttattaaat
    45001 agaatccttc gtattttttt gttctatcac tacaatatct ttatttggac gtttgaattg
    45061 tattccggca cgttctagct cctgtttcac tcctacatgg actttgacat cttctcgtgt
    45121 catttttaaa acgtgatgaa tcgcatagtc gatttcttgc cttgtgattt ttttcttcgt
    45181 attgatcatc acgacttgct ttttatcata tgtgtctacc aatagcagtt gtgttcgatc
    45241 taacgaaaat aatttgtaat aattaatagc cgtattccca aaaaagaatt ccactacttt
    45301 aggataaaat gtcttaatat ttaaattact attcacaggt gtttcgatta gcttcatctc
    45361 attcctcttt tctatatagt cgatttagat ccaatcttaa gttatgttac catctttcct
    45421 agcattaagg aatcggttac aattgaacct ttaaagacaa aaggatttac cttttatcac
    45481 ttaatagtat aacataattt catgagaaaa aaatacaatt ttttcttgac catctcgtta
    45541 cgtaaaggat tatgcttaca tttgtcagga ggaaaaataa tggagtacac aataaagaaa
    45601 atgtcagaga tatcaggagt cagtccgaga accttgcgct tttatgatga gattggactg
    45661 ctaaaaccag ctaggatcaa ttcttcaggt tatcggattt atggcaaaaa agaagtcgat
    45721 cgtctgcaac acatcttatt ttatcgaaca atggcattca agttggatga tatccaagag
    45781 gtcttagaca atccatcttt tgaccaccag aaagctttaa tcaagcatca gcaaatgttg
    45841 ctggaaaaac gggcacaaat cgataccctc ttgacaactg tccaacagac acttgatatg
    45901 tacgaaggag gaagaaaaat gagtgacaaa gaaaaatttg aagggtttaa acaacaaaag
    45961 ttgaaagaaa atgaagaatc ctatggacaa gagattcgac aaaaatacgg aaaaaaaaag
    46021 gttacagcat ccaatgaaaa atggatgaat atggataaag aaacgtatga agaaatgcaa
    46081 actgttgaaa agcagatgtt atttgatctc actctttact taaaagaacc agaagatgaa
    46141 agcttagcag accgtatctt ccaagctcat aagaagtggt tatcttacag ctggcctgaa
    46201 tatcagccaa aagcgcataa aggactagga atgatgtacg aagccgatga acggttcact
    46261 gcatattatg acgagcgaag tggtcatggt gcagcaaaag ctttaaatga aattatccaa
    46321 aaaaaggcgt aatcttttac atgatccaac aaaaaagtac acgtaaaatg acctaataac
    46381 aaaacagcag acacccaagt tagattttta tgctaacttt tggtgtctgc tccattcttt
    46441 cacaagtttt ttcatcctac tttaaatata ttcatcgttg aataaacgta taaggtattt
    46501 tcactttatc ctttttttct gtaagaaaca attgaaatgc catttctccg caagcttcca
    46561 gatggtggtc gatggttggg aaaccaagaa gctcgctgat cagcaaatta tcgcgtccaa
    46621 tcaccactgg tgtcttatct tgcagatagc tttgcaagat gcctgctgca accatatccg
    46681 aatttgtaaa gacaccatca actccaagct ctttaaaaaa gaagcctgct tgttttcctt
    46741 tctctgcatc tatacaatcc caaaaaacaa gtgattcatc aaaagatgga aaaagttgat
    46801 gacatagctg caaagtgatt tttgagttat aacttagcct gccacttcgc cccaacgtga
    46861 tgcccaattg ctttatacct tgctgcttca aataagtaag accttctgta attgattgtt
    46921 ctcgatcaat aaagacacag cttgcctgtt ttcccttgat ttcttcacaa aaaactagag
    46981 gtccatattt ttgatatgcc aataaatcat ctagtgtatt ggcacgagac gtaatgatca
    47041 atccatcgaa agctttagct gcaaattctt caagatacct tcgctctttt tctttctgat
    47101 agcccgtcgg taaaagtgtc actttgtaat cataatcaaa cgctgcttca atgatcccac
    47161 tgatcaactg atcaaaatac ggatgattgg tataaggcag aatcactcca atgcttttcg
    47221 tttttccata acttaactgt ctggcatttg cattagggat ataatcgact tctttcatga
    47281 ccgcaagtat ttctttcctt ttttcctcat ctacatatgg atgtccattg attacacgtg
    47341 aaatagtaga aactgaataa cctgtgagct ttgcgatatc tcgaatgttt gccactgctg
    47401 cttcgccacc tatacaaaaa gattttcttg taaatagtct accacagctg gaccgcattc
    47461 aaaaaactga tacatttttc cttcatgcga aaaactgatc cgctgcccgc cccaatatat
    47521 atcttttgtc aaattttcga tttcattcat tggtatttct tttactatat tcctattcaa
    47581 cccttgaaaa ctgtacaacg ttaatacgga tcccttgaac tcgacaaacg cataaaaata
    47641 attgttcgtt gtgccatctg ttatctctac ataagtattc attgcaagcc ctccttttga
    47701 tactttgagt atagtgtatg aaacgcgtct catagcaagg agtttgtttt gccaaagaaa
    47761 agttttattc ctctttcatt attaccaaag tctcttattt taaattgaat acattataat
    47821 gatactgtaa atatatcttt attattagtg a
//
LOCUS       DAZULR010000021        47469 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.021, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000021 DAZULR010000000
VERSION     DAZULR010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 47469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47469
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.021"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(54..788)
                     /locus_tag="ACG8ZV_001312"
     CDS             complement(54..788)
                     /locus_tag="ACG8ZV_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HFS4996663.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1115..1525
                     /locus_tag="ACG8ZV_001313"
     CDS             1115..1525
                     /locus_tag="ACG8ZV_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HFS4996664.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1518..2219
                     /locus_tag="ACG8ZV_001314"
     CDS             1518..2219
                     /locus_tag="ACG8ZV_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HFS4996665.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2219..3805
                     /locus_tag="ACG8ZV_001315"
     CDS             2219..3805
                     /locus_tag="ACG8ZV_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4996666.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3824..4045
                     /locus_tag="ACG8ZV_001316"
     CDS             3824..4045
                     /locus_tag="ACG8ZV_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HFS4996667.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4042..4803
                     /locus_tag="ACG8ZV_001317"
     CDS             4042..4803
                     /locus_tag="ACG8ZV_001317"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HFS4996668.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5183..5692
                     /locus_tag="ACG8ZV_001318"
     CDS             5183..5692
                     /locus_tag="ACG8ZV_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HFS4996669.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5767..6306)
                     /locus_tag="ACG8ZV_001319"
     CDS             complement(5767..6306)
                     /locus_tag="ACG8ZV_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HFS4996670.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6446..7057)
                     /gene="rpsD"
                     /locus_tag="ACG8ZV_001320"
     CDS             complement(6446..7057)
                     /gene="rpsD"
                     /locus_tag="ACG8ZV_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HFS4996671.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7319..8170
                     /locus_tag="ACG8ZV_001321"
     CDS             7319..8170
                     /locus_tag="ACG8ZV_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HFS4996672.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8198..8833
                     /locus_tag="ACG8ZV_001322"
     CDS             8198..8833
                     /locus_tag="ACG8ZV_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HFS4996673.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8853..9626
                     /locus_tag="ACG8ZV_001323"
     CDS             8853..9626
                     /locus_tag="ACG8ZV_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFS4996674.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10034..10831
                     /locus_tag="ACG8ZV_001324"
     CDS             10034..10831
                     /locus_tag="ACG8ZV_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HFS4996675.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10809..11222
                     /locus_tag="ACG8ZV_001325"
     CDS             10809..11222
                     /locus_tag="ACG8ZV_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFS4996676.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11206..13851
                     /gene="mutS"
                     /locus_tag="ACG8ZV_001326"
     CDS             11206..13851
                     /gene="mutS"
                     /locus_tag="ACG8ZV_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HFS4996677.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISSVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13869..15977
                     /gene="mutL"
                     /locus_tag="ACG8ZV_001327"
     CDS             13869..15977
                     /gene="mutL"
                     /locus_tag="ACG8ZV_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HFS4996678.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15999..16559
                     /locus_tag="ACG8ZV_001328"
     CDS             15999..16559
                     /locus_tag="ACG8ZV_001328"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphatase"
                     /protein_id="HFS4996679.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16644..18632)
                     /gene="treP"
                     /locus_tag="ACG8ZV_001329"
     CDS             complement(16644..18632)
                     /gene="treP"
                     /locus_tag="ACG8ZV_001329"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HFS4996680.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18855..19568
                     /gene="treR"
                     /locus_tag="ACG8ZV_001330"
     CDS             18855..19568
                     /gene="treR"
                     /locus_tag="ACG8ZV_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HFS4996681.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19645..20091
                     /gene="msrB"
                     /locus_tag="ACG8ZV_001331"
     CDS             19645..20091
                     /gene="msrB"
                     /locus_tag="ACG8ZV_001331"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HFS4996682.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATEQPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20261..20863
                     /gene="ruvA"
                     /locus_tag="ACG8ZV_001332"
     CDS             20261..20863
                     /gene="ruvA"
                     /locus_tag="ACG8ZV_001332"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HFS4996683.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNEKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20876..21877
                     /gene="ruvB"
                     /locus_tag="ACG8ZV_001333"
     CDS             20876..21877
                     /gene="ruvB"
                     /locus_tag="ACG8ZV_001333"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HFS4996684.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21906..22484
                     /locus_tag="ACG8ZV_001334"
     CDS             21906..22484
                     /locus_tag="ACG8ZV_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFS4996685.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22536..23018
                     /locus_tag="ACG8ZV_001335"
     CDS             22536..23018
                     /locus_tag="ACG8ZV_001335"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HFS4996686.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIAIEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23135..23509
                     /locus_tag="ACG8ZV_001336"
     CDS             23135..23509
                     /locus_tag="ACG8ZV_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996687.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
     gene            complement(24187..25539)
                     /gene="brnQ"
                     /locus_tag="ACG8ZV_001337"
     CDS             complement(24187..25539)
                     /gene="brnQ"
                     /locus_tag="ACG8ZV_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HFS4996688.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
     gene            25686..26276
                     /locus_tag="ACG8ZV_001338"
     CDS             25686..26276
                     /locus_tag="ACG8ZV_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HFS4996689.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            complement(26404..27753)
                     /locus_tag="ACG8ZV_001339"
     CDS             complement(26404..27753)
                     /locus_tag="ACG8ZV_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFS4996690.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(27921..28661)
                     /locus_tag="ACG8ZV_001340"
     CDS             complement(27921..28661)
                     /locus_tag="ACG8ZV_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFS4996691.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            complement(28674..30266)
                     /locus_tag="ACG8ZV_001341"
     CDS             complement(28674..30266)
                     /locus_tag="ACG8ZV_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015837 - amine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFS4996692.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     regulatory      complement(30404..30578)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes
                     and Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
     gene            complement(30834..31130)
                     /locus_tag="ACG8ZV_001342"
     CDS             complement(30834..31130)
                     /locus_tag="ACG8ZV_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996693.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            31306..32031
                     /locus_tag="ACG8ZV_001343"
     CDS             31306..32031
                     /locus_tag="ACG8ZV_001343"
                     /EC_number="2.3.1.286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0034979 - NAD-dependent protein lysine
                     deacetylase activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HFS4996694.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEMAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            32024..32866
                     /locus_tag="ACG8ZV_001344"
     CDS             32024..32866
                     /locus_tag="ACG8ZV_001344"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HFS4996695.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELIALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            32869..33390
                     /locus_tag="ACG8ZV_001345"
     CDS             32869..33390
                     /locus_tag="ACG8ZV_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HFS4996696.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(33643..34206)
                     /gene="def"
                     /locus_tag="ACG8ZV_001346"
     CDS             complement(33643..34206)
                     /gene="def"
                     /locus_tag="ACG8ZV_001346"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFS4996697.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            34457..34726
                     /gene="rpsO"
                     /locus_tag="ACG8ZV_001347"
     CDS             34457..34726
                     /gene="rpsO"
                     /locus_tag="ACG8ZV_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HFS4996698.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            34914..37040
                     /gene="pnp"
                     /locus_tag="ACG8ZV_001348"
     CDS             34914..37040
                     /gene="pnp"
                     /locus_tag="ACG8ZV_001348"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HFS4996699.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            37550..37816
                     /locus_tag="ACG8ZV_001349"
     CDS             37550..37816
                     /locus_tag="ACG8ZV_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFS4996700.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            37960..39951
                     /locus_tag="ACG8ZV_001350"
     CDS             37960..39951
                     /locus_tag="ACG8ZV_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HFS4996701.1"
                     /translation="MATTHNTKKISMAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGL
                     SGINPDFVIGSVSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLII
                     PAMIGGAALLADGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFM
                     VQRFGTDIVGKAFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKL
                     GLFILGNIFLATTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQN
                     PEAQQIKNLNPFFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPR
                     LKIMYPGNSIGQMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALL
                     YFYLIQNGHSRWLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWE
                     QGNIIRESSTEDVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSI
                     LDKRPKRARVYWFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQ
                     VIHDLMKQGRLPKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAI
                     KKIATSPETWFGLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            40305..41606
                     /locus_tag="ACG8ZV_001351"
     CDS             40305..41606
                     /locus_tag="ACG8ZV_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HFS4996702.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYYYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKTE"
     gene            complement(41736..43106)
                     /locus_tag="ACG8ZV_001352"
     CDS             complement(41736..43106)
                     /locus_tag="ACG8ZV_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFS4996703.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(43288..43611)
                     /locus_tag="ACG8ZV_001353"
     CDS             complement(43288..43611)
                     /locus_tag="ACG8ZV_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HFS4996704.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            complement(43936..44544)
                     /locus_tag="ACG8ZV_001354"
     CDS             complement(43936..44544)
                     /locus_tag="ACG8ZV_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0008097 - 5S rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HFS4996705.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEEESTGEGGEPEVIGSTEE"
     gene            44874..45590
                     /locus_tag="ACG8ZV_001355"
     CDS             44874..45590
                     /locus_tag="ACG8ZV_001355"
                     /EC_number="5.4.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0140098 - catalytic activity, acting on
                     RNA [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HFS4996706.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            45603..46298
                     /locus_tag="ACG8ZV_001356"
     CDS             45603..46298
                     /locus_tag="ACG8ZV_001356"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HFS4996707.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            46382..47011
                     /gene="udk"
                     /locus_tag="ACG8ZV_001357"
     CDS             46382..47011
                     /gene="udk"
                     /locus_tag="ACG8ZV_001357"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HFS4996708.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
BASE COUNT        15391 a         8788 c         9877 g        13413 t
ORIGIN      
        1 taaaaaaact tggtacgcaa tcgctgtacc aagttttttt atttagcttt tgattaagcc
       61 ataaataata atttatataa gaatactgct acgacaccag cacagatagg tgctacaact
      121 ggtacccatg catatcccca ttgagaagaa cctttatgtt tcaatggaag aagtgcgtgt
      181 acaagacgtg gagcaaagtc gcgggctggg tttagtccag gacctgtagg accaccaagt
      241 gaagcaacta atgtccatac aaggaaacca agtgctaagt gagctgtacc aagattatct
      301 tggaagaatg gtgcttttgt aatacctagg gcaccaaaga ataaaacgaa tgaaccaaag
      361 aattcattga cgaaaccatt gaatttagaa ccaacgctgt tgattgttga gaatgtacct
      421 aacacatggt ttacgtcttc tgtttggtcg tagtaaggtt tgtaacaagc tactacgatc
      481 aattgtccaa tcgctgcacc aatcaattgt gcaatgatat aaggaacaac ttcagcccaa
      541 gggaatagac cattagatgc taaagcaatt gtaaatgctg ggttgatgtg gttaccgctg
      601 attccaccaa aaatcattgc tggcatcata accccgaatc catacccgac agcaatcagc
      661 atccagtcac tgccatatcc ttttgtacct tttaaatcta cgtttgctac agcaccgtta
      721 cctagaacga ttagtaatgc tgtaccaatc atttccgccg caagacgggt cattagtgag
      781 taatccataa atacctccaa aagttataaa aatgcaaaaa aaaaagaaac atcaacacga
      841 aaagcatcgg tgcagtgttt cgtgtcggaa ggatttctgc agtcttaaca aatgtgaata
      901 aaaaaatgaa ttccattact tataagaaac cagaccaaca gtaaaactcc aactcttttt
      961 aaaagttctc cacaaatcac caagcttaac tataaatata ccaaaaaaaa aacgtttttt
     1021 ttctcaaaaa ttgtatctta gaaacagcat gttttgaaac tttcagaaaa ggtttgttag
     1081 taaaatgaaa gctatacgta aggagtgttg tttgatgaaa ttttttcaag agtttttcat
     1141 tattattttc ttttctgtat taggagaagg catacggatt tttgctcatt tacctattcc
     1201 tggaagtatc ttaggtattc tttttttatt tttagcattt gaaatgcatc ttgttgatcc
     1261 tgaaaaaatc ggagcaactg gtgatttttt attgaataat ctagccattt tatttgttcc
     1321 tgctggtgta ggtttattgg aatattttga tgatattgct tcgatatggc ctgttttact
     1381 gggagcagtc gtcgtgtgtt ccatcgtcac gatggttgca gcgggaaaaa cggcagaagg
     1441 tgtagaagct ttgctgggct atgtccgtaa gaaaaaagca gaaagggtat ctgtaaacga
     1501 aatggaggag aatcaaattg actgagtttt ttgtgaatcc attatttggc ttaagtttga
     1561 ctttaggagt gtacgtatta tctgacaaat ttttgcggaa atataaactg cctgttttga
     1621 atcctctcgt attatcgatt gttgttatta tcttattttt gcatttttct gggatcagct
     1681 ataaagacta taatatcggg ggcaattttt tgactatgct gattactcct gcgacagtgg
     1741 cacttgccat ccctctttat aaaaacttcc gtttactgaa agagaatttt tatcctgtaa
     1801 tggctgcgat tttagcagga atagtcgcaa attgcttggt tagtgtaggg ttcggttact
     1861 tcttctctct tcataaagag atggtgatct cattactacc taaatctgta acgacggcta
     1921 tttctgtcga tttatctcat acgatgggcg gggtgaatgc cgtgacactt gctattgttg
     1981 tctctacagg tatttttggt tcgctgatcg ccactcatat tttccgccta ttcaagatcg
     2041 aaagtccagt tgctcgcggt gtggcgttag gaagtacttc tcatgctatt ggtacagcaa
     2101 aagcaatcga gattggtgaa atagaaggaa tcatttccgg acttgcgata tgcgtcaacg
     2161 gaatattgac cgttttattg ctaccgttat tctttcagcc ttttgctggc ttgttttgat
     2221 gcgaaaacca ctattttatg ctacaataac caaaacgttc gagcataaaa aaggagggaa
     2281 agacgtgtat ttgtcttccg agtatcttaa acaatttgat aaagatctat attataagat
     2341 tctcctccta gaaagttttg aggatcaagc ttggcatacc gctgcacaat tagcgcaagt
     2401 tgttcagctg gatgcccgca gcgtgtcgaa atacctgaac gagctgtcta aaaactatca
     2461 gcagtttagc ggtaagacac accctttgtt tacaaaaaat caccgttctg gttataactt
     2521 ttatgatacg ctcgattcaa ttgaacatga gcgttttttg atctatctcg tgcaaagtac
     2581 gctgaaattc cagttgctgc acgacatttt ttttgaagaa ttccatacaa tgtaccaatt
     2641 tgcgcaaaag cattacatta gtgaatctac tgctcatcga aaaatcaatg aatggaaaca
     2701 gcaactgcaa acttacggaa ttcggctgca acgaggtaca tatatcgctc aaggcgaaga
     2761 agaaatcatt cgactttact tgcatatgac attctggcag ttgtttcgag ggaaaatctg
     2821 gccatttgaa acgatttctc aaatggacgt aaagaatatg gcagaacata tcatggcttt
     2881 ttttaatgtt cgtctgaacg agatcaaaaa aagacgattg gaatatatgc taggtgcctt
     2941 ttttttaaga aaatcacaga agcattatgt tgtattgaat gagaaaaaaa gacggctgat
     3001 ttctgacaat ctgttgttcc agcgattttg ccaggtcatg gagccggtat ttcctaatta
     3061 ttttcaagta gaagacgagt taggcgcatt atttcttgta ctgatgactc gtgaagaata
     3121 ttatagtgat cctaagatac ggaagaaaat ttttgatttt catcaacaag caaaaacacc
     3181 gccctttaca gccctttcag aagcaaaagc cgctctttct ctttatcagg aagagcaggg
     3241 gctgccagca gaaaatctaa ccttcgaggc agaaaactat ttattcagca gtcatttttt
     3301 cgcctatctt tttcctaatg cgaaagaaac gattgatggc aatagtagtg attttattaa
     3361 tcatttagtt attgaaaaca aggaattgaa acaatggctc gtacattttt ttgaaagtag
     3421 acacaaacat cccaatcatc tggcatttaa aaatcatgcg tttttgatgg ggcggtatct
     3481 gactgtgttt aaaacattag gagcctttac tccacagctt ccaaagatca cgatcctttt
     3541 aatgacagat ttcccattat ttgaagagca actgttagag gagggattac ggacattttt
     3601 ccgtaatgag tatcagctga tttttctgcc aacagattat cgggggagag aagttgatct
     3661 tctgatttcg acaagtaaag tccaccgcaa accatgggcg gatcttgact attttattgt
     3721 gactgaagaa ctaaaattaa ttgattacat ccaactatct caaaaatttg aaatgattca
     3781 aaaacaaaaa ctattaaaac aataacaaag aaggagaaaa aagatgacat ttgaagaaat
     3841 tttaccagaa ttgaaaaaag gtgcaaagat tattcgtaaa ggatggagtg gatttgaact
     3901 ttatgttgtt ctcgtatccg atgatgaatt tgatggctgt ccggtgacgc cgtacttatt
     3961 gatcaaaaca agtgacgaag gtttttccag cttcgctcct acagtttgtg atattttagc
     4021 agatgattgg gcgatcgtag aatgaaaaac cagtatccag atctagctaa acaggttgta
     4081 tttatcacag gagctgcttc tggaattggt gctgcgcaag cccgagcgtt tcttgaacaa
     4141 gatgcttttg tatttggatt agatcaaaag ttcggtaaaa tggaagaaat ttctttgcga
     4201 tttcctgaaa cttttgccta cgcactaggt gatgttcgac aaatgaaaga actccaacaa
     4261 gcggtatcga aatgccaaaa tcattttggt gaagttacga ttttactgaa tacagcgggg
     4321 atattggatg cctacaaacc cttgatggaa actgacgaat cgctgtggga tctgatttat
     4381 gagacgaatg tgaaaagcat gtatcagctg acaaaaatca tccttcctga tatgatccgc
     4441 caaaaaagcg gaacgatcat caatatggct tcgattgctg gcttgattgc tggtggaggt
     4501 gggatcgctt atacaagcgc gaaacatgcg attgtcggat ttaccaaaca actcgctctg
     4561 gattacgcag gacagggtat ccgagtaaaa ggaattgctc caggagccat ccaaacacca
     4621 atgaatgcgg ctgattttga agggaaaggt gagatggcag agtgggtggc aaatgaaaca
     4681 ccagtcaagc gatgggcaca gccggaagaa gtagctgagc tgacgttatt tcttgcctct
     4741 cctcaagcaa gctacataca aggaacgatc atcccaatcg acggcggatg gttgttaaaa
     4801 taaccttgtg tttttttcaa gcttctgtat gataaaacta aagagagaaa caacggttga
     4861 tgataaaaaa agtcgatgac tgttcccgac attcgatgcc gaacagccag ttcaaaaaat
     4921 tctttttaat aatcgttaat attcgaaact aagcggcttt tcacgacctc ttgatataaa
     4981 cgatattcaa aagcttgcaa ctgcggtaac aagtccagcc aaatgaaaaa tataaggagc
     5041 tatttttatt tgaccattct tattacttgt tgcagggcag ctttttcact accttctgcg
     5101 acacttcagt tggaattttc ttcccatcct ttggtcgcgg tcattaccaa gataaaatta
     5161 tcttgcaaag gagaaataga acatggaaaa aaataatacc cgttcagcca aacgctggac
     5221 aacgacagat gtgactcgga tggcgctagt cactggttta tatgtggcag tgacgctggt
     5281 tttgtctgtc tttagctttg gagtgattca gattcgtctc tcggagatgt tcaactatct
     5341 gtccttgtat aacaaaagat acatcgtcgc ggtaacagcg ggagtagctt tggctaatat
     5401 tgcttctcct cttggactga tagatgttgc agtaggaagc gtcagcacgc tgcttgtatt
     5461 gcttatcaac tataaaatca ctagtcgcat caaaaacatg aaaatcaaaa tggccgtgac
     5521 agcatgcgta tttgcttttt ccatgtttac agtagctggt cagctaacga ttttatatca
     5581 actacctttt ttcttgaatt ggtgggtgat tgctttagga gaattggcat caatgattgt
     5641 cggtgggata attatttatt ggatcggtaa aaaagtggat ttgtcaaaat aaagatctgt
     5701 ttaatttaaa atagggcagc atggaagaga ctgaatgttg agtcttcttc catgctgctt
     5761 ttttgattaa tttgtatgaa gaaatcgatt tagccgtttt ttcatcaaga taccgatata
     5821 agctgctcca gttgccttga ttgcttccgg cagtaaaaac ggcagtagtc cactggcaaa
     5881 tgcagttgta aaagtaagat caccacttat tttcagccag atcgttccgc agatcaatgc
     5941 agcaagagag cccattagat tggcaaagat tgcatataag taatgagcat ccgttctttc
     6001 gatcatccaa ccagttatcc acgtttgtaa gagaaatcca atcaaatatc cgccagttgg
     6061 cccaaataaa acagctatac ctccagtcat ccctgaaaat acaggaagac caatcaagcc
     6121 aagtaaaaga taaactccaa cagatatcaa tcctagtttt cttccgagaa aagttgctgt
     6181 taatccaata gcaaatgttt gccctgtcaa aggaaccaaa ccaaaaggaa tggtcatctg
     6241 agaaaggaca gaaataatcg cggcaaattc cgcagcaagt atcaattctt tcaatgttcg
     6301 gttcataacg ccctcttttc gttaacttaa tatttttatt tggttaacga aattgtaaaa
     6361 caaagtgatt actttgtaaa tagaaaatat aaaaaaagac cagctatcca atagatagcg
     6421 gtctttttca agaaagcttt tgaaattata agctttggtt gtagtattca acgacaagag
     6481 cttcgtcgat ttctggatat agttcgtcac gttctggtaa acgagtcaat gaaccttcca
     6541 atttttcagc gtcaaagctt acgaatgctg ggcgtccaac agttgcttct acagcttctt
     6601 ttactgttac gatgttttgt gatttttcac gaactgagat cacttgaccc acttctacgt
     6661 ggtatgaagg gatatcaacg cgtttgccat caactaaaat gtgaccatgg ttaactaatt
     6721 gacgtgcttg acgacgagtc gttgcaagtc ctaaacggta aacaacattg tctaaacgtt
     6781 gttctagtaa gatcatgaag ttaacaccat gtttaccttc tttgattttg ctagctttta
     6841 cgaacaagtt acggaattga cgttcgttca ttccgtacat gtgacgaagt ttttgttttt
     6901 cagttaattg catgccgtat tctgattgtt tgccacggct attaggtcca tgttgacctg
     6961 gtgcgtaagg gcgacgtgct aattcttttc ctgtgcctga caatgagatg cctaagcgac
     7021 gagaaatttt ccatgatggt cctgtataac gagacattaa aatttcctcc aatgaatata
     7081 agtttttgga gtaaaataat ccgttgaaaa attcataatc atatagtttg ttcttcaatc
     7141 ttcacctttg cagccgcggt tacacaatcg aacccgagac ggggcaacaa actagggatg
     7201 agttattatt tttctgctgc attattttac acaaattaca gtatatgata gatcatccac
     7261 gaatgtcaag ataattagta cataaaaacg ctttacaaac ctaggctgtc tttataaaat
     7321 gagagggtat gtgcaaatgg aaaaaagcga aggaagttta aggagaaaat caatgaatcc
     7381 ggtatcacca ttatttgaga aaatcgatgc ttcaattgaa aagaaggcga atctttttga
     7441 aaacagcttt tcacgttacg ctgttcgagc ggttctcgcc tgtttgtttt tgactttagg
     7501 aacggctgtg gcatttgcga tcgcgatgaa gggggaagat atcgcgcatg gtctaggaaa
     7561 gattttatac gcatttatgt tcagctgggg tctggtcatg attctataca tgaacgccga
     7621 attaggaaca tcgaatatgc tttatatgac cgtgggtgtt tttcggcaga gacttgcttt
     7681 aagtaaggca gccaagattc tatttgcctg tatttttttc aatatgattg gcggtatatt
     7741 atgtggattt ctaatttcta tgactacgcc atttcaagat ttaacgttgg acaactttat
     7801 gttagaatca atagcagtaa aactagcaaa accttcagca acgattttgg tggaagggat
     7861 gtttgcgaat atcgttgtca ataccgctgt actgatcagc atgcggatga aagaggatgt
     7921 cggaaaagtg atcacagtcg tattcatcat tttcattttt gcttttttag gatatgaaca
     7981 cgtgatagcg aattttcctg cctttacgct tacttacttt gcttctcacg gacagatgga
     8041 tggaatgaca gtcagcaatg tgttacataa tttgtttttt gctttggcag gaaattatat
     8101 tggtggcggt ttagtaatgg gactgggata tgcttggctg aatcagtcaa aatcatccta
     8161 tgtggactaa aaagtcgttc attaaagggg aagtgccatg gaagttttag tttttccaaa
     8221 aaatgaggaa aaagcgttac aaatggaaaa gtacatgaaa aatctttttt cctttgctgg
     8281 agtacctaag ccggaacgcg ctcttttaca acaaccgtta ctggatgaga gcaaaaattt
     8341 atctatttct gaagttttag cttttgttca ttattattat gaacaaatcg aaagagagta
     8401 tcagtatgta gcgatcgatt tagtccagaa aaacatcaaa cggcttacat ttgaagactt
     8461 agtcgtattg ttgccactag ttcagaaaaa agaatggtgg gacagcatcg actcttggag
     8521 aaaagtatac agcacatggt gtaaagccta cccagagcag cgtgaagaag tctttcaatt
     8581 gtttgaaaaa aaggaagatt tttggctacg tcgaatagca atcacgttgc aattaggtta
     8641 taaacagcaa acagacacag gactattgat ccgagcaata gacgaagatc gtcaaacaaa
     8701 ggaattcttt atccaaaaag caattggttg ggcattacgc gattatagta agaccgatgc
     8761 cgattgggta aaaagacagc tgacaacaga tttgagtaag ttagctgttc gagaggcaag
     8821 taagtattta taagaaagcg agacgacaag agatgagacg caaattattt gcttttgata
     8881 ttgatggaac gttgttagat tcaaacaaac aagctttaga tagcacaaga gaagcattgg
     8941 aaaaattacg caaagccggt catctggtca cgattgctac agggcggagc cgatttcatg
     9001 cgcaagagat cattcgcgat cttgatttta cgaactacat tttatgtaat ggagcggccg
     9061 gttttttaga ccatgaacaa gtatataaga atttactaga tcgcgaccag ttggatgcgt
     9121 tcgttcaaga agcgcatcat gagcagatcg atacagcttt tgtcagctta gacaatatca
     9181 agcgttcttc ttccaatgat gtaacggtga tggaagaagc gatgcattct ttcggtgctg
     9241 tcttgcctga attagatcag ttttttgcag aggaacaaga aatataccaa gcgttagcat
     9301 ttttcgatca aacatatgat gggaagttct cttcatatga taaaattcga tttgtccgct
     9361 ggcatgagaa cagtgtagat gtcgtaccta aaaatggttc taaagcagcg acaattctgc
     9421 acttagcaga acaagtaggc atccctcatg aagacatcat cagctttggc gatggacaaa
     9481 acgaccgtga aatgttgcgc atgtcaggaa ttgggatagc tatggggaat gctgtgccag
     9541 aagtacaagc agaagctaag atggtcactg atacaaacga tcaggatgga atttggaagg
     9601 cattgaaaga gttaagcgtg atttaaaaga ggttgtgaaa aagctgttct gcatcaagta
     9661 ataagcccag ccaaacaaaa atagctcctc ctatttttcg tttttctggg cttattaccg
     9721 cagatgcaag ctttcgaaca ccgtttaagg aagaggtcgt gacagaagtg gtcagtttca
     9781 agaaataaga agggatttac gaaaattgct tctcaaattt ttgtaaaatt acggcttatt
     9841 tctgaagaag tagatgaaac aacgtttatt cgggaaatgg gactgtgaca agatgtttgt
     9901 catagtccca tttttttatt ttatttttca aaactaagaa ataccaggaa agagttcctt
     9961 ttgtttgacc ttttctttct tattgaaaac aactataata tagagtgatg ttaaaagaga
    10021 agaggaattt agtgtgcggg tattgtttat tggtgatgta gtaggttcaa tgggacgaga
    10081 gatgattact gaatatcttc ctagattgaa gaagaagtac cgtccgcaag taacgattgt
    10141 aaatggtgag aatgccgctt ctggacgtgg aatcacagaa aaaatctata aaaaattttt
    10201 gcaagacggc gtagatgtcg tgacgatggg gaatcatacg tgggacaacc gcggaatctt
    10261 tgagtttgta aatgaagcta aaaagatggt tcgtccggca aattttccgg aagggacgcc
    10321 tggacaaggg atggtctttg tcaaagtgaa ccaagtcgaa ctggcagtga tcaacatgca
    10381 ggctcgttct tttatggtgg acttggatga tccttttcgt aaaatgaatg agctggtaga
    10441 agaagccaga aaacgtacgc cgatcatttt tgtagatttt catggagaaa caacaagtga
    10501 aaaacaagca atgggctggt ttttagatgg gaaagtttca gcagtggtcg gtacacatac
    10561 acacgttcag acaaatgatg cgcgaatttt gccaagagga acagcgtatc tgacagacgt
    10621 tgggatgaca ggtccctatg atggtatttt gggtatgcgc agagaacctg taatcgaaaa
    10681 gtttctgact gcattaccaa aacgttttga agttgtggaa caaggccgat cgattttaag
    10741 cggctgtatc ttggaattgg atgatacgac aggtcatgca aaagaaatcc agctgattca
    10801 gatcaacgat gatcgaccgt tcatggagta gaaagagagg cagttttttg cagcaggagc
    10861 cggaaattca aaaagaagta aggaaactga caaaactttt aagagagaat gaaacgatca
    10921 ttcgctacaa agaacttgaa gaaaagatcc agcaaaacca gtatttagct gagttgagag
    10981 aaaaaatcaa acaagcgcaa aaagatgctg ttcattttgc ccactatgac aaaccagcag
    11041 cagaaaaaga agcaatcaaa caagcggatc aattcatgca agaatttgat cagcatccgc
    11101 ttgttgtagc ttatagaaaa cagctgttgg aagcagatga tctgcttcat catttaacaa
    11161 ctatgataca agaagaaatc aatggacaaa tagaggagga aaaacatgcc tcaaaaaact
    11221 aaaaatactc ctatgatgga acaatatcta agcatcaagg cccaatacca agatgctttt
    11281 ttgttctatc gtttaggaga cttttatgaa ctattttacg aagatgcgat caaagcgtca
    11341 cagcttttgg aattaacgtt gacgagcaga aatcgaaatg cagaagaacc tattcctatg
    11401 tgcggtgtac ctcaccatgc agcacaagga tatatcgatg ccttgattga aaaaggctat
    11461 aaagtagcga tttgcgagca ggtagaagat ccaaagacga ctaaagggat ggtcaagcgc
    11521 gaagtgatcc agctagtcac tcctggtaca gtcatggaca gcaaaggatt gtcggcaaaa
    11581 gacaacaatt ttttaacagc tgtagttagt caaggaaatg aatttggctt tgcttatgcc
    11641 gatttaagta cgggagaatt gaagacggct cggttgcatg atgaagaagc tgttttaaat
    11701 gaagcctctg cattgcagac aaaagaactc gtattaggca gtgagatcac tgataccctt
    11761 cgtgaacagc taagcgggcg tttagggcta gtcttttctc aacaaaatga gatggaagaa
    11821 aacgcggaat ttagcttttt gacaagcgaa ctagtcgatc cgctggaaaa agaagcaacc
    11881 ggcaaactat tgacttattt atcggtgaca caaaagcgga gtttagctca tatccaaaaa
    11941 gcagtagaat accaaccaga tcattttttg aaaatggatt attattcaaa attcaaccta
    12001 gaattaagcc aatctattcg gactgggaaa aagcacggca ctcttctatg gttgttagat
    12061 gaaacaaaaa cagcaatggg tggccgttta ctaaaacaat ggctagaccg tccgcttatc
    12121 caggcaaaac aaattaaagc aagacaagaa atggtcgctt ctttgctaga cagctatttt
    12181 gaacgtatcg atttgcagtc agcattaacg aaagtctatg atctggaacg cctagcaggt
    12241 cgagtagctt tcggtaatgt caatgggcga gacttgatcc agctgaaaac ttctttagaa
    12301 caagtgccaa tgatcagagg gttgattgaa ggaatcgatc aaggtcaatg gcaaagtctg
    12361 ctttcagaaa tgcagccgat ggaccatctc gtccaattga tcgaccaagc tatccaagat
    12421 gatccgccgt tacaaataac ggaaggaaac atcatcaaag atggattcaa tgagcagctc
    12481 gatatgtacc gttctgctat gagaaacgga aagaaatggt tggcagaact tgaagcaaaa
    12541 gagcgtcaag aaacaggaat caagaactta aaaatcggat ttaaccgcgt tttcggttat
    12601 tatatagaaa ttacaaaagc aaatcttgga aatgcagaac tggagaagta tgaacgaaaa
    12661 caaactttag caaatgcaga gcgtttcatc acaccagaac taaaagaatt ggagacacaa
    12721 atcctcgaag cagaagaaaa atctgttgat ttagaatatc agttgttttt agctgtgaga
    12781 gaagaagtca aaaaggctat ccagccgcta caagtacttg caaaagcaat cagttcagta
    12841 gatgtgctac aaagttttgc aacgatcagc gaacgctatc agtatgttcg gccagaactt
    12901 gtcagtgaca agcatcagct tctgatcaaa gacggacgac atcctgtagt agaaaaagta
    12961 ttaggacatc aggaatatat ccctaacagc gtagaaatgg cagaagacga aatgatcttg
    13021 ctgattacag gaccgaatat gtctggtaaa agtacgtata tgcgacagtt ggcattaact
    13081 gttctgatgg cgcaaatggg ctgtttcgtt ccggcaaaac aagcagtttt acctattttt
    13141 gatcggattt ttacccgaat tggtgcaagt gacgacttaa ttgctggaca aagtactttt
    13201 atggtagaga tgatggaagc caatcaagcc ctgcgttatg ctacgccaaa cagtttgatt
    13261 ttgtttgacg aactagggcg aggaacagca acctatgacg gaatggcgtt ggcccaagca
    13321 atcatcgaat atatccatcg tcatgtacaa gcaaaaacac tcttttctac tcattatcat
    13381 gaactgacgg tacttgagaa agaacttccg cagcttaaaa atgtccatgt tggagccgtt
    13441 gaaaaagacg gagaagttgt cttcttgcat aaaatgatgg atggacctgc ggataaaagc
    13501 tacggcatac atgtggcaaa gatcgcagga ttgccttcca atctactaga acgagcagca
    13561 gatatcctgc atacgctaga aaatggcgat aacggacacc atactgttcc agctgaagta
    13621 gaagagaaaa ctaaaacagc caaacaggag caaataaaac cacctgcaga aaaagtaaat
    13681 caagaccata tacaagaccg tgtaaaagaa gaaaaccaac agctttcttt attcagtgaa
    13741 ttatccgaaa atgaaacaga agtcattgaa tcactgaagc aaataaattt actagaaatg
    13801 acgccaatgg atgcactaaa cacattatat gaattacaaa aacaactgta ggaagaaggc
    13861 ggatatcgat ggccaaaatc caagaattat ctgaacgttt agctaatcag atcgctgcgg
    13921 gagaagtagt ggagcgacca gcttccgttg tgaaagaatt agtggaaaat gcaattgacg
    13981 ccggcagtac tcagattgat atcttagttg aagaagcggg actgcggacg atccaagtga
    14041 ttgataacgg agaaggcatt ttggcagacg acgtagagaa tgccttcaag cggcatgcga
    14101 caagtaagat ccataatcgc gacgatcttt ttcgcatacg aacgctgggc tttcgagggg
    14161 aagctttgcc aagtattgcc tctgtttctg aaatgactct ggaaacggcg aatcaggaag
    14221 aaaaacaagg cacctatctg tcgctgaaag gcggagaagt tattgagcat cgaccagcac
    14281 cactgcgtca aggaacgaag attaccgtca gcaatctgtt tttcaatacg ccagcccgct
    14341 tgaaatacgt gaaaacactg cacacagaat tagcgaacat cggggacatc gtcaatcgac
    14401 tggcattgag tcatccatcg attgcttttc gtttagtaca tgatggaaac aaaatgctgg
    14461 caactgctgg aaatggcgat ctgaaacaaa caattgcggg aatctacgga ttatctaccg
    14521 caaaaaaaat gctgaaaatc gaaggaaaag atctagattt tgagttattt ggctatgttt
    14581 cattgcctga ggtgactcgt gccagtagga attacttatc gacgatcatc aatggacgtt
    14641 ttatcaagaa cttttccttg aataaagcaa tcgttgcagg ttatgggtca aaattaatgg
    14701 tcggtcgttt ccctattgct gtattggaaa tcaaaatgga cccgctttta gtagatgtaa
    14761 atgttcatcc gacgaagcag gaagtccggc tgtcgaagga aaaagaacta acagagctaa
    14821 ttagtaacgc cattcaaaaa gcattgtctc aagaaaatct gattccaagt gcagcggata
    14881 atctacggtt taagaaaaaa gtacctgatc agcctaaaac agaacaaatc gaaatcgatt
    14941 tgtcctacgc ttttgaagaa gaaaaaccta aaaagccaag tagtttgaat tttgatcgag
    15001 agacaggtac ctttttcgta gaagaactaa agaacacatt tgttgacaga attgttgata
    15061 agtctgtgga aaatgttgaa aactattctg gtttttctga agaaaacacc acttatccag
    15121 aaaaaacagc gaaaacggtg gataagtttg gtgaaaatgt tgataacttt gtagaaaaaa
    15181 cagtggaaaa atctgaaaag aaagaatttc ccattgtgga taacatggag aaaacaaatg
    15241 aagaacaagc agataaatcc gtagaagagg atgaaaagat ttacgaggaa gaattgacac
    15301 tccatcctga atttgatttc actcaaggaa acgacaaaac attagaacaa gccatcaaga
    15361 aattagaaac ggaaaaacca gtacaacgtt ttcctcagtt ggaatatttt ggacagatgc
    15421 acggaacgta tctttttgcc caaagtagcg atgggttgta catcattgat cagcatgctg
    15481 cccaagagcg cattaagtat gaatatttcc gggaaaaaat tggggaagta tctgatgatc
    15541 tgcaagaatt gcttgttcca tttgtgttag actatccaaa cagtgatgct ttgaaattaa
    15601 aagagcaaaa acacttgcta gaagatgcag ggatttattt agaagaattt ggtcaaaaca
    15661 gctttattgt acgggcccat cctacttggt atcccaatgg agaagaagaa tcgattattc
    15721 gggagatgat cgatatgctg ctgacaactg gaagtgtgag tgtaaaaaaa ttccgtgaag
    15781 caacagcaat catgatgagt tgcaaacgat cgattaaagc caaccattat ttgaatgaag
    15841 cacaagcacg tgtgctgctg aaggatctgg cacgatgcga aaatcctttc aattgtcccc
    15901 atggccgtcc agtattgatt cactttacca attcggatat ggaaaggatg ttcaaacgaa
    15961 tccaagaccc gcattaagtc aaagagaaga gggaaaacat gaagattgta ttagcatccc
    16021 aatcaccaag aagaaaagag ttattggctc atatcgtttc agaattcgag attgaacctg
    16081 ctgatatcga tgaaacgcca tttccagacg aacagcccgt cgattatgtt cgtagaatgg
    16141 ctgaagaaaa agcacgaact gtctgggaac aagatgaaaa agaagaccat ttagtgattg
    16201 ccagtgacac gactgttgtt ctcaatcaag agatcatggg taaaccagaa gatctggctg
    16261 aggctgaatt catgctgaaa aaactaagcg gggaaacaca tactgtatat acagctgttg
    16321 ttttaaaaac aaaggaacga gaagaacgga tactagcaga agcacatgtc actttttatc
    16381 ctttgacaga cgaagagatc aaacgctact tggagacggg ggattatgcg gataaggcag
    16441 gggcatacgg catccaaaat gctgcgagtg tattcgtcaa agaaatttct ggagattatt
    16501 acagtatcgt aggatttccg attggtgctg tcaatcaggc actgaaaaca ttcatttaaa
    16561 caaaaaagcg gactatctga ttttcgattg aaaatccatg atagcccgtt ttttttattg
    16621 aaaagattac ttatctactc tgactaagat tttacttcag ctttaccgac tgcttcgccc
    16681 gggcgaacaa gtcctgattg gtcaagagaa agtcctgcaa ctttttcatt attggtcaaa
    16741 gcaacaataa tgtcagtttt cttgccagct tgttctattt ctggcaaatc catttcagca
    16801 atcagggtct ctggtgtgac aaggtatcct tctttcacga atacattgaa aggaacaccc
    16861 tttagttcaa cagtatctaa tcccatgtga acaagtactt ccagcccctc attagaaaga
    16921 ataccaatgg catgttttgt ttcaaagaca ctcgtcactt taccgtttac tggtgcatag
    16981 actttgccgt ttgacggttc gacagcataa ccgtcaccca tcattttttg tgagaaaact
    17041 gggtcattta cttcagttat ttccttgatg gtccctgcag cgactgcgaa taatgtttct
    17101 tttgttgcaa ctgccgtacc agttgctgaa acaggttcga aagactgtgg cgttgctgtt
    17161 gcgccatttg ctgtttgaag ttgtacatca gcagcatttt caggaacagc aggatcaatc
    17221 ttattcaaaa ttccctgacg tctaaagatg atcgtcaagc caaatggaat gatgacagca
    17281 atgatcattg cgatgatgaa aggtacccat gtttctgctt ggatagctag tattcctggc
    17341 aaaccgccta ctccgatcgc gttagctcga acacccatca agttagcaaa catgccagct
    17401 aatccagagc cgaccattgc agcgacgaaa ggatagacgt atttcaaatt gattccgaac
    17461 atagcaggtt cagttacgcc taagtaacaa gaaatcattg ctggaatcga gatttgttct
    17521 tcttttttat tcccacgatg taagaagatg atggctaaga ctgcagagcc ttgggcgata
    17581 tttgataaag caatcatcgg ccataaattc gttgatccga aatctgcaat cagctgcata
    17641 tcgatggcat tggtcatatg gtggagacca gtaatcacta aaggagcata caggaatccg
    17701 aatacggcac taaacaacca gctgatagaa gacgtcaatc cagtatttac gatatttgag
    17761 atccagcttc cgactgtcca gccgatagga cctaaaataa cgtgtgcagc taaaacagtt
    17821 ggtaacaatg aaaacaatgg aacaaaaatc atcgagatcg actgagggat atatttgcgg
    17881 aagaagattt ctagatacgc taacataaac cctgccagca tggctggaat aacttgcgct
    17941 tgataaccaa tcatctggac ttgagcaaaa ccaaaatccc aaaatggaat atctgctgcg
    18001 gctgtggaag ctacactata agcatttaat aattgcggag aaactaacgt aattcctaaa
    18061 acgattccta atatttgtgt agtacccatc ttttttgcaa tactccaagt gatacctact
    18121 ggaagaaaat ggaaaattgc ttcacccggt aaccacaaaa aggcattgac accattccaa
    18181 aacttcgagt gttcaacgat tgttccacca agactttcaa actggatacc ttcaagtaca
    18241 tttctgaatc caaggatcaa tccaccgaca atgattgcag gaatcagtgg tgtaaagatt
    18301 tctgctaaaa cggcaatagc acgttgaacg ggatgaaggt tttgttttgc agctgctttt
    18361 ccttgttctt tggaaacccc ttcaactcca gatactgcaa cgaagtcgtt ataaaaagta
    18421 gaaacatcgt ttcctatgat gacttggaac tgtcctgcat tcgtgaacat cccttttacg
    18481 ctaggtatat cttcgatcgc tttttcgtcc gcttttcctg gatcattcag gacaaaacgc
    18541 atacgagtcg cacaatgact aactgcagca atattttctt ttccgccgat atcatgtaac
    18601 agcttctcgg catctgcttg atattttgcc atatcaataa acccctttct cttaacttgt
    18661 ctatgcaagt tgtttcttca tttactatac tttttttcgg agagaattgc aagcgtttta
    18721 ttaaaaagta cgagagaaaa tgatatcgtt ttaaaaagct taaaataagc ttttcttaaa
    18781 aataggaaca ttgaaataca aaaagagctg tagtatagtg aagaaatgat ggaagaacga
    18841 gtgagggaaa aaacatgaat aagttcaatg aaattttttt agatttggaa cagaaaattt
    18901 tagcgaaaga atatcctccg cattcgcttt tacccagtga gaaccaattg atcaaaattt
    18961 atggtgtttc acgagaaaca attagaaaag cgctgaatct tttgactacg gaaggttata
    19021 ttcaaaaaaa acaaggaaaa ggttcgatcg tactggatcg gaatcgcttc gactttccta
    19081 tttctggatt gactagctat aaagagctac aggagaccca acgtattcca agtgaaacga
    19141 tcatccatac gttagaagaa acagaagtga caaaagcatt gaacgagatc actggctggg
    19201 agatcggtgc gcctgtttgg catttgatac gcgaaagaaa aatcaatggc gaagtagtta
    19261 tattagacac cgattatcta ttaaaggaaa tcgttcctat tttaactcca gcacaagcac
    19321 aaggatcgat ctatgaatat tttgaaaatg agctttcttt gacgattgct tacgcgcaaa
    19381 aggagatcac agtagaagaa gtaacggaaa tcatgaaaac agcgatggat cttcacgatg
    19441 acacttatgc agtagtagtc agaagcctcg ttcatctgga agatacccgc tgtttcgagt
    19501 attctgagtc ggttcaccga ttagataaat tccgtttcgt tgagtttgcc cgacgccgaa
    19561 aagtgtaaat agttcaaaag aaagcaaatt gttggcatct gtccactttg gcgctatgat
    19621 aggatcacaa agggggcatt tttaatggat aaaccaataa gaccagaaaa agaagaactg
    19681 aaagaaaagt tatcacccat ggcttatgca gtcacacaag aaaatgcaac agaacaacca
    19741 tttagcggga aatatgatga tttttacgaa aaggggatct atgtagatat cgtcagcggt
    19801 gaaccgttat tcagctctgc agaaaaatat gatgcaggtt gtggctggcc atcattcagc
    19861 aaaccaataa cgaaaagaca agtgcgcgaa aaagccgatt tttctcatgg catgcatcga
    19921 atagaagttc gaagcaaaga agcagattct catctcggac atgtgtttac cgatggacca
    19981 gtagatcaag gtggtctacg ttactgcatc aattctgcct cactgaaatt cattccatat
    20041 gaaaagatgg atgaattagg ttatggggaa ttcaaatcac ttgtagaata atggaaatac
    20101 acaaagagcg gtacaatacg gggatttact cgatcgtccg ctcttttttt attcaagcga
    20161 ttgctatttg aaagaaacgc tccctagact ccttttttca caaggtgaaa tgtgctacaa
    20221 taaagggaac gtatgtgtgc aaaagaaaga ggactagaat atgtatgaat atctgacagg
    20281 tgtggttacc tttatcaacc cctattacat agtagtagaa accaatggta tcggctacca
    20341 gatcgcacta ggaaatcctt accgctacag tagcaaacta aatgaaaaaa taaaaattta
    20401 tgtccatcag gtaatacgtg aagatgcgca tcttctgtat ggatttgatt cgctagaaga
    20461 aaagcaactg tttttgcgat tagtaagtgt ttcaggaatc ggtccgaaaa gtgcccttgc
    20521 aatcatggca agcgaagacc actccggttt gattcaagca gtagaatcca gtgatgtcac
    20581 ttatttgacg aaatttccag gagtagggaa aaagacagca caacaaatga tcttggatct
    20641 aaaaggaaaa ttcggtgagc tgagtatcga tacacctttt agtctatttg atgaagcaaa
    20701 cacaaaagac gctacagctc tatctgaagc aatggaagct ctctcggctc ttggttacag
    20761 tgatcgagaa atcaaacgtg tagaaaaaca attaaaagaa gtagataatc agacaacgga
    20821 tgagtatcta cgccaagcac tcaagctaat gatgaaaaaa taaggaggag accaaatgac
    20881 agatgaatac ttgttatcac cagaatctgg cgaaaatgaa ctgagtttgg aaaaatctct
    20941 tcgaccacag ctgctttctc aatatatcgg acagagaaaa gtcaaacaag aacttcagat
    21001 ttacatcgaa gctgccagaa atcgggaaga acctttagat catgttctgt tgtacgggcc
    21061 tcctggatta ggaaaaacga cgatggccat ggtcattgct aatgagatga ccgtaaatat
    21121 tcgtacgacg agtggccctg ctatcgaacg tccgggtgac ttagtagcaa tcttgaatga
    21181 actggaagca ggggatgtcc tgtttatcga tgagatccat cgattaccta gagtggtaga
    21241 agagatgctt tattcagcta tggaagattt ctatgtagat atcatggtag gacaagggcc
    21301 aaccgcacat ccggttcatt tccctcttcc tccctttact ttgattggcg cgacgacacg
    21361 ggcaggtatg ctttctgcac ctttacgaga tcgatttggc atcatttctc atatggaata
    21421 ttatgacgaa caggatctgc aggagatcgt tttacgttct tcggatattt ttcaaacaga
    21481 gatcattgaa gaaggggcat tggaaattgc tcgccgatca cgaggaacgc ctagaatcgc
    21541 taatcgcttg ctcaaacggg ttcgtgattt tgcgcaagtc caaggagacg ggaaaatcga
    21601 tcgtcctata gcggatcagg cacttacttt gctacaggtc gatcaggctg gattggatta
    21661 tgttgaccag aaattgttgc gaacaatgat cgagttatat ggcggcggac cagtagggtt
    21721 aagtacgctt tcagtaaaca taggagaaga gcgtgagacg gtagaagata tgtatgaacc
    21781 gtatctgatc caaaaaggat ttttaaagcg tacacctaga gggcgaattg ctactgctta
    21841 tgcctatgaa cattttggtt acgactatca tatatgattt ttgcttttag attggaggaa
    21901 aatgaatgag tgatacaaca cgtacgaaac aattgatcaa aaacgtattg attgatttgt
    21961 gccaaacgca atcttttcga aaaatcagcg tccaaaaaat cgcaaatgaa gcaaaaatca
    22021 atcgacaaac attttattat cattttacag ataaatacga tttgcttcgt tgggtctatt
    22081 gtgaggatgc attgcattat ttagatccac aatgtctttc acttgataat tgggaagagc
    22141 aagcattgaa aatgctgaaa gcaattgctg agaagaaaga attttatgca aatactgtgc
    22201 tttctgaccc agaaatttta caaaaagagt tttctcaact gatccaaaaa tcatttatca
    22261 agatttttga acaaatggat gaagaaagac aactttctgc aagagacaaa ctattttatg
    22321 ctcgtttttt ttcttacggt tgcagtggtg tattagtcaa ttggatcacg aatgaatatg
    22381 aagaaacacc gatggaaatc gctatgcagc ttttccgttt agccaaggat acggaattat
    22441 attcttatcg tctttatgca aaagaagagt tggaagaaca gtaatagaaa aattttttgt
    22501 tggaaaagca ataatcgcta aaaggagatg gggaaatgac aaaaatttta tttgtttgtt
    22561 tgggaaatat ttgccgttca ccgatggcag aaggcttgct gagaaaacga atagcaatag
    22621 aaggaaggga agcagaattt tttgtggatt ctgctgctac aagcacgtat gaagttggaa
    22681 agacaccgca ccctggaacg aaaaaaatat taaaccaaga aaaagtagat atgacgaata
    22741 tggttgctcg gcaaatcaca ccccacgatt ttgaaacttt tgattggatc attggcatgg
    22801 atcaagaaaa tgtagaagaa ctgaaacgaa gagcaccacg ctcagcgcag gggaaaatcc
    22861 atttgttttt aagtagcatt cctggaaaag aaaaagaaaa tgttcccgac ccatactata
    22921 ccaataactt tgatgagaca tatcacttga tcacagaagg cctgaatcat tggtggaata
    22981 tttggattga cgaaaataaa ataacaaaca atttgtaaag ttgacgcttt ctttttaagg
    23041 cgatgttaga gcatttcctt gtttttttgt aaaatgttag gtaaaataaa attaattaag
    23101 taacactttc ttagctaaag gaggagtgca ttcgatgaac gaagagacag tatcgccaat
    23161 gaagaagctt acgaagttag ttactcatac ttcgtatcaa ctttttgatt cttttgtaaa
    23221 tgacactgaa gaacatgcta agaatgtacg attgcaagga aaatttattc ttgagctgca
    23281 aaaagctgct actgaacata gtctagttat cttacaagta agagcgaatc gtttgagtag
    23341 caagtatgaa acgatctcag gctgggtggc gacaaaaacg gtcgaaaaag accgagtgat
    23401 gatccgccta caaaacgaag agcagcagat ccggatggtt cctgtagaac aaattgaaaa
    23461 aataacaatc ctttcaccag caggggaaca ggaacgatta tcaaaataat ttataccaga
    23521 tagaaaagca cgtatgagct tgtaccatca atcattacta atcaaaaata accgaatgct
    23581 ttaagctgat atcagtaaaa cggaacgttt taggatgagt atcacagcat gacagcattg
    23641 ggttgattag ttgaatcgat tggatggtac aagttttttt gataaaaaaa ggtcctgcta
    23701 gccggggagc tagcaggata aggagttaaa aatgaaaaag tgttgttagg gttgtttgtt
    23761 ggtatgctta tataatagtc actagttgtg aatattttgt gacgaaagtt ttcgaaagtt
    23821 gttaagtttt tttgcgaaaa ctatttttat atcatatata tgtctaaaat ctatattata
    23881 aaagaaatgt tgtttgatca gcttctcttc ggtattagtt caaaacaaaa cggcaaagta
    23941 tatggagcta ctttgccgtt ttgtttctct aatactcagg tcagtttata gacgctcaat
    24001 aaacggtgtt caaaagccag tttctcggta ttaagtcaaa tttatgcaaa aatgtgagaa
    24061 gccattttca aaaaatattt cttaatactc gaaactgagc ggctttttca cgacctctca
    24121 ataaacagtg ttcaagagac agcctatcgg caataaggct gaacgtctct ttcacaacct
    24181 cttttatcaa tctgctactt cttctttctt agcgaaactc caaatcagtc cgataacaaa
    24241 accgataact gctggtacga tccaccccat ccccaatttg aaaaacggca agtagctttc
    24301 cgcaacatat aaaagatttt gaacaatagg tgtttgtttg atagtttctg ggcaagcgtt
    24361 caacccatca aaaatcgaag caatcaatgt aaaataagta gtcattcgat aaacagccgt
    24421 acgctgctta aacaaaggac caactaacac tagtaaaatc agtgtcattg ctaatggata
    24481 gatgaacatc aaaacaggca acgaaaattg aatgatattc gtcaagccta cgtttgccgc
    24541 taaacaagga aggatactag caagtgcaac aaagaatgcg taatttcttt gcggaaacaa
    24601 atctgtgaat gtttctgcaa aagctgtaat caaaccaata ccggtcttca agcaagctaa
    24661 tataacgata aatgctaata agatactgcc ataagtacct aaataatgat cagcaatctg
    24721 agccagcgtg atcccgccat tttcacttag agcaaagcta cctaagctca tagcacctaa
    24781 ataagcgagc aaagtataaa tgattcccat caatataatg ctgatcgcac cagatttgat
    24841 cgtgtcttta gcgatttcag caggttttgt tacacccatg ttttggattg ttgtgacaat
    24901 gatgatccca aatgctaaag cagcaagcgc atctaatgtg ttatatcctt gagtaaaccc
    24961 tgtgaaaaaa gcatgctctt gataatttgg ctgaataggc gcttgattta cagaacctag
    25021 tggattcaaa aaagcaagga gaagcaaagc acctaataaa accaaaaatg caggattcag
    25081 gaactttcca acataatcta atatctttgt cggttttctt gaaaaccacc aagccagcac
    25141 aaaaaataca atactgaaaa ttgctagata tagcgtctgt ctgctaggat cgataaatgg
    25201 tgctaaacca atctcgaaag atgtggttgc aaggcgaggt aaagcaaaaa acggtccgat
    25261 aactaagtaa agcaagatgg taaaaaccat cgcatatgtt tgatttatcc gttttgctaa
    25321 ttcatataca cctgagcttt tcgatacacc aatggcaatc acccctaaga agggaagacc
    25381 gataccggta accaagaaac ctagattcgc ccaaaaggta gcagcgcctg cttcttgacc
    25441 caaatgaacg ggaaagataa gatttccagc accaaaaaat agaccgaaaa gcatggagcc
    25501 tataaaaaga tagtctttaa atgataattt ttttgtcata cataactcct ttacggtttt
    25561 tttaaaagta acaaaatttc gaaaaatatg caacaatttt cagaaaattt cctatataaa
    25621 acgacggtta tttaataacg taagtgataa aataaaagcg ctgaatcatc tgaggaggaa
    25681 tcatcgtgac aaagtcgaga ttagaagcat ttactgatgg agtggtagcc attgttttga
    25741 gagttcttgt attagagatc aagatcccta atacatctag ctttcattct ttatgggtca
    25801 tccgaaatac attattagct tataccatca gctttatatt tgttgcggtg atctgggtga
    25861 accatcatcg tatatttcag atggcagaac gaattaatta ccgagtggtc tggtcgaata
    25921 tctttttgct cttttggctg actttatgtc cttctgttac tagttgggtc gggcgtaacc
    25981 ctgaagcttt ttggcctgag atggcttatg tcttagtata cacgatgtgg agtttttctt
    26041 ttggtatctt gatgaggcaa atcatgaaag caaataaacc agattcccat gtcgtgagag
    26101 ttttgtcaaa ggaccgtcga agtcttatct ccatgatgat taacttatgc ttgattgccg
    26161 gtgtcttttt tgtaccgttg atcgggttat tcggacgttt ttttgtatct ggtatttgga
    26221 ttttttccta taaaaaagca gatgcctatt atcagcggtt gtttccgggg aaatagaaaa
    26281 gaggctggga cagaagcttt taactccaag aaataagccg aaatttcaca aaaatttaag
    26341 aagcaatttt cgtaaattcc ttcttatttc tcgaagctga ccacttctgt cacaactact
    26401 ttcttacttc ttacgttcat atttcatatg atagattagt aatagaagca agaaccacac
    26461 aggtgttagt aataaagcga ttctcgtatc ttttcctagg aacaagacga cacacacaaa
    26521 ggccatgtaa agaaatacca gataattact aaatgggtac aacggcattt taaatgaatg
    26581 agcttttttg ccgaggatac ttttacgata tttcatgtgc gtgtagacaa gcatactcca
    26641 gataaacaag aaacaagtag tggcaatact gcttactagt gtgaatactt cactaggcat
    26701 cacgtaattc aagataacag aaatgaaaat gacgatagta gaaaatgtca aagcattccc
    26761 tggcacatga tgtgttgtta actttttgaa ttttttaggg gcactgcctt cttgcgctaa
    26821 agaacgaagc atacgtcctg tactatatat tgcactgttg caggcagaag ctgctgcact
    26881 taatacgact aaattgatca aggaagcagc aatcgtgatc ccaatttccg aaaatacttc
    26941 tacaaatgga ctgttatctg gattcaagct gttccatgga tagattgcca taatgacaaa
    27001 aagagatcct aagtaaaata agatgatcct gataggaata ttattgatag cttccggcaa
    27061 cactttttca ggattttctg tttctccagc gactaatcca actaattcta tcccagcaaa
    27121 agcaaaggtt accatttgga aagctaagat aaatcctttt gcaccagttg gaaagaatcc
    27181 gccatgagac catagattcg tgatactggc tgtgccaata tctgtcgtat agtgggtgag
    27241 gatcatataa gctcctacga ggataaaggc aatgatcgct acaactttga tcaatgcaaa
    27301 ccaaaactct aactcaccaa acaatgagac agccaccata ttcaagcaaa gaagaagacc
    27361 taatgcaatc agttcaggaa gccactgagg aacaccaggc gcccagtagc gtacatacat
    27421 tccgatggct gttaaatcgg ccattgcaat cgatacccag cagaaccaat acgtccagcc
    27481 agtgatgaaa gccgcttttt tgccaagata ttctgcaaca aaatccagaa aagaatggtt
    27541 attggtgttt gataacagaa gttcgcctaa cgcacgcata atgaaaaaac agatgcatcc
    27601 agtaataaga taggcgagca atatcgaagg gccagctagc tggatagact ttccggaacc
    27661 taaaaacaac cccgttccaa tcgctccgcc aatagaaatc agttggacat gtctattttt
    27721 cagtccacgc tgcagttctt gctcttcatt catttttaaa tcatcctaac taaaaaagtt
    27781 taattacttc catattaaaa gagttttctg aaaaacacaa ctaagattcc aaaattttca
    27841 gaaatttacc ttttatgagt aattcataaa aaagaactgc ggtaaacacc gcagctcttt
    27901 gtcccaatca gctattgatc ctaagcattt aaaatacgtg aaaggaattc ttttgtacgt
    27961 tcttctttcg gatggacaaa gatatcttct ggtgtacctt cttctgcaat cacaccttta
    28021 tccataaaaa tgacacggtc agatacatct tttgcaaatt ccatctcatg cgtcacgata
    28081 agcattgtca agccagtatg tgctaagtct ttgatcgtat taagcacttc gccaaccatt
    28141 tcagggtcta acgccgaagt aggttcgtcg aatagcaata catctggatt cattgataat
    28201 gcccgagcaa ttgcgacacg ctgtttctgt ccaccagata attgtgctgg tttggcttcg
    28261 atataacgat ccataccaac tttttccaga ttttcgattg ctactttttt ggcagtttct
    28321 ttatctcgtt tcaggacagt tgtttgacca gacatacagt tttccaagac attcatattg
    28381 ttgaacaggt tgaaggattg gaaaaccata cctagattcg ttcgatattt aggtaaatta
    28441 tatttaggag ctaatacatt ttctccatta taaatgatct cgccgcctgt tggtttttcc
    28501 agtaaattga tacagcgcaa gaaagtagat ttaccagaac cggaagaacc gatgatcgtc
    28561 acaacttcac ctttattgac tgttacgctg atatctttca atacttcatt ttcaccgaag
    28621 ctttttctta gatgtttgat ttcaataatt ttttcattca tgattcttcc tccttattcc
    28681 tgcaaatttg aattgtcgat ttcttcaagc ttggtataag ctgaaggacc atcgattttc
    28741 ttttctaccg cccgcaggat tctggtgatc gtaaaggtca tgactaagta gatgatcccg
    28801 acgatcgtaa atgtttggaa gaattggaaa ttcgcaccgg aagcagagtt tccttggaag
    28861 aacaaatcag ctacgccgat tacacttaaa actgctgtat ctttgatatt gataacaaac
    28921 tcatttcctg ttgctggcaa gatattccgt aaaacttgtg gaataacaac ttttctcatc
    28981 gtttggccat gggtcatacc aatggcttgc gcagcttcga actgcccttc atctactgca
    29041 aaaatccccc cacgaacgat ctctgtcatg taagctccag tattgagaga gacaataaac
    29101 aaagcggcaa tcgttcggtt caatgaaatg ccaaaagcga gtgccagacc gtagaagatg
    29161 accattgctt gtaccatcat cggtgttccg cggaatactt cgacatagat agaaagaagt
    29221 gcatttccga ttttttggaa gaagcgagtc agtgcatttc ctgattcagg taccgaacgg
    29281 aagacaccaa tcagtaatcc aagtgtagta ccgacaactg tcccgatcaa tgcgatgaac
    29341 aaggtaagtc cagcacctcg taagaacata ttgccgtatt gtttccaaat cgtagtgaaa
    29401 tcagaaatga tgccaggttt ttcttcacta tcagttgcag caggctgatc tttgactgct
    29461 tggtccataa ttttggttcg ttcatcgtta gagatgccag aaagaatctg gtttactttt
    29521 tggatatccg ggtcgccttt acgcatacca acagaaatct gaacatcttc cgggtttgtc
    29581 tggaagccat ctgcaccgct gaattcaagc atttccaagt ctttgttcac actagttgcc
    29641 gttacacctt ccggacgttc gctgacataa ccatcgatca ttccagaagc taaagctgtt
    29701 ctcattgctg agaaattatc cattgcttgt tgtttctgca catctggtat ctgatcgatc
    29761 acagtatagt ggaatgtatt taactgagca gtaatctttg ctccagaaag atctgctaaa
    29821 ctttttgctt ttgcatattt gctatctttt tgaactacta ctactaattg tgattcgtaa
    29881 taaggatcgg taaaatcaat ttcttttcgt cgttcagcag tagggctcat tccggcgatg
    29941 atcgcgtcga tcttgcctga ttgaagggca ggagccagac catcccattt cgtttggacg
    30001 atgactaatt ttttccctaa accatctgct acttttttag cgatttgaac atcataaccg
    30061 ccggcgtaac tattttggcc ttgaattggc aaggcattat tctcatctgt ttgttgagac
    30121 cagttgaagg gtgcataccc agcctccata cctacgcgaa actcatcgct cggtgttttt
    30181 tcatctgcat ttgccagaga tcccacactg aatagtgaga agacaaaagc aaatagtacg
    30241 gcaactgaaa ccatattttt tttcattttt ttctcccttt ctgattatat gatacacgag
    30301 cggtctagat gaaatgcggt aaagctttat ctgaaaaaat aaaaagcgac cgatttatag
    30361 atataaaaag gccgctaaaa ttccataagg tgataaacct ctcacaaaac atagcgcaac
    30421 ttagcatcac tgctaagaca gtccgcaagc tcttaacttg cgtcccaaca tacactccaa
    30481 gcaaaaaagt gcacatttcg gcgatcctcc ctattcctgc ttctccatgt ttgcttcact
    30541 ccacagggtt aatgattctc gcgacctcta cctcattgat tgaggcatct cgtattcagt
    30601 tatttataca aaaaaagttt acgatactcg agaggctttg tcaatctata actgctgttt
    30661 tttgaaaaaa tactgataaa tatagaaatc tttactttta ccgaaaaaac aatcaaaatg
    30721 tgaatcatct atccattgca aacgatagta taattataca caaaaatgta tgtaatacaa
    30781 taaaaaaaga actagaacag aaaatttcct gtgtccagtt ccatctcgat catttaagct
    30841 gccgctttct ttggctcacg tcctaggatc gcttgcaaaa gaacaacgac gccataaatg
    30901 gctaatatta gataaatcaa acttgagtat tgggtgattc cccagcccca tgttcgatat
    30961 acggctaatg taatggctaa aacaattgcg gcaatcacgt tgaataaagc aaaagcccaa
    31021 agatttccat tttctttgcg tacaagataa aaaacagaga aataaacgct taacgctaac
    31081 caggcgatac aagccagaat aacgccccaa taaataaaga atggtaacat atcgattcac
    31141 ctcactttta tacagcagta ttgtaacacg ttttcattct tttgtcagtg aacattgtga
    31201 taaattgttc aaatgcccat aacacttttt tattcccatt tttctgactt ttcaacaata
    31261 aatttgttcg agtatgggct ataatggaaa gtgaggtgac aaaacatgaa acaattaaca
    31321 gtagacgaag cagcaaaaga gatattagct tatcagcaaa ttacattttt gaccggtgca
    31381 ggggtatcca caccttctgg agtgccagac tatcgatctt tgtcaggaat ctaccacggg
    31441 atggagcagc cggaatactt gctgagtcat caagcaatgg tgaatgaacc ggataaattc
    31501 tatcaatttg tcaaaaagat ttatcatcct gaagcaaaac ccaatatcat tcatttggaa
    31561 atggcacatc tagcgaaaga aaaaaatgtt tgggttgttt cccaaaacat cgacggtttg
    31621 cacgcaaagg ctaaaagccc gcaactcgtc aattttcatg gaagtttgta tcaatgtcat
    31681 tgtcgaaaat gtcaacaaac ggtagactgg aaagaatatc ttcacagcga caaacatcaa
    31741 gcatgcggag gacaaatacg cccagacatc gtgttatatg gtgaagggtt tcaagatgga
    31801 gtcatggagc aggcggctta tgccgtcagc caagcagagc tgatcgtcat tgttggaacg
    31861 agttttcaag ttcatccgtt ttgtgatctg gtacagtttc gccagccgtc agccaaaatc
    31921 ttagtaatca atcaaacgcc tgtttattta gcggagcctt atacgtttat tcaagaagac
    31981 ggagcggttg ttttcaaaaa aatacaagaa ttaggagcag attatgactg aattcaaaac
    32041 cgaaaaagaa aaaatgattg caggcgagct ttattttgcc aatgatcctg agctggttgc
    32101 cgaccgtatg tttgcaagaa gtcaaagcca aatcatcaac caagcagaat cagcggaact
    32161 gcgatcccaa ttgttgaaag agacttttgg ccgtacaggg aaaaaaatct atatggagcc
    32221 agttatcaat tttgattacg gatataatat atttgttggg gagaattttt atgcaaattt
    32281 caattgtaca tttttagatg tcagcacgat tgaaatcggt gataactgca tgttcgctcc
    32341 gaatgtccag ctttacacgg cgacgcatcc actacatcca gtgaaacgta acagcggtct
    32401 ggagtacgca aaacccatta aaatcggtaa taatgtttgg ttaggcggag gagttatcgt
    32461 cacgccgggt gtcactctag gggacaacgt agtagtcggc gcaggttcgg ttgtgaccaa
    32521 atcttttccc gacaatgtag tgattgcagg aaatcctgct cgtatcatca agacagtaga
    32581 ggaagaacta acagaagagt ctcttgaaac attacgtcat aagatcgata tgatcgatcg
    32641 agagttgatt gctttattag aaaaaagaat ggatacggta actaaaatag gacaagtgaa
    32701 aaaagaagaa aaccaagcag tttatgatgc aaaaagagag cagcaagtat tggataaagt
    32761 tgttagtctg ctgaaaaata agggatataa ggaaacaata acagatacgt atgttgattt
    32821 gatgaaacac tcgcgcgaat accaaaacaa aatgaaggag gaataagtgt gatcgaagga
    32881 gagacacggc gaaaacaaat catgcaaacc ttggcaaata cagaaaaacc agtgagtgct
    32941 agcaagtttg cgaaaacttt tggagtcagc cgtcagatca ttgtaggcga tattgcttta
    33001 ctacgagctg caggtaaaag tatcgtggca acagcaagag gttatatcct cgaaacagaa
    33061 gaaaccaata ctgggcacat cagtaaaatc gctgtccagc atggaaaaga tcaaacagaa
    33121 gaagaactga gactaatcgt tgaaaatggt ggtgaaatca ttgatgtaat tgtggaacat
    33181 cccctttacg gtgagttagc aggaactttg cacatcaaaa cgccacaaga tatcgattcc
    33241 tttatgagac gttatcaaaa aagtaatgct actttgttat ccgaattaac aggcggcatc
    33301 catctgcata cgatccgcta cccagaaaag catatgctga aaaacatcaa acaaaaacta
    33361 gctgaagcag gaatcctcta cgaaggataa catcgtagct gctacttttt atcctagaaa
    33421 ctattctatc atctctgaga taaacaccca tatggaagaa ataagaaaaa ataagaaaag
    33481 atgcgtatcc aatacacaga attttttgga attgcgattt ctagatgtct atctaaattt
    33541 cgattagtgg agaaacataa aaaagggaag tgcagctttt gagcactccc cttttttata
    33601 aagctttctt gtagcatagt atcgaaggaa cctgccaatt ctctactcga tcaccaatac
    33661 gccttctttt agtgcaaatg gattttgatc gttgatgtgg tcatagaaca tcacaccgtt
    33721 gatatggtcg atttcatgtt gaacgacgat cgattcataa ttcttcaaac gaatcttgtg
    33781 tttttcacca ttcatatcat aataagacac agtgattttg gcatggcgaa caacatatcc
    33841 tggtacttct cgatcaacag ataaacagcc ttcaccttcc cctaaacaag catcttgaac
    33901 agaatggctc aaaattttag gattatacat aacagtactt agagaaggtc catctgcctc
    33961 tgggtcagga cttggtacgt gaacagcaat gattctttta gaaatatcta attgaggagc
    34021 agctaagcca acaccgcctc gtaagtgtag ttcttcagct ttgattggat cttggctgtt
    34081 ttttaagaac tcaagcatct cttttcctaa agagatatct tcttcgctta atggaagaga
    34141 aacttctttt gcaacttcgc gtaaggtcgg atttccttca cgaatgatat catccattgt
    34201 aatcatggaa tatgtacccc tttcttaaaa gactgtgttt caagtctatt ttcgcattat
    34261 agtttaccac aaaaatggaa aagtagtagt aagattgttt gaaaactacc ttttcttaat
    34321 gattaactac ttgattttca acccggtttc aggtaaagta tagctgtgtg ctctaggcac
    34381 atgacctgcc acttggttaa gcgaatcacc aacgttttac tcagtcgcag gggaataatc
    34441 gaaagaggtg aaagaaatgg caatttcaaa agaacgcaag aatgaaatca tcaacgaata
    34501 cgctcgccat gaaggggata ctggttctcc agaagtacaa atcgctgtat taactgaaga
    34561 aatcaaccac ttgaatgaac atgcacgcgt gcacaaaaaa gaccatcatt cataccgcgg
    34621 cctaatgaaa aaagttggtc accgccgtaa cttgttagct tacttacgta aaactgacgt
    34681 tcaacgttac cgcgaattga tcaaacgttt aggcttgcgt cgttaatttt agtcaaaaag
    34741 agtgggattc acatgaatct cacttttttt actcgtatat caattaagta aaattccgtg
    34801 atcaagctag atggactcct actaaccaaa tgaaagctgc tcaaaagacg gctttcggca
    34861 gttttcattt gtttagtagc gtcttgcttt cacgagaagg aaaaggagaa gttatgtcag
    34921 aaaaacaagt attcaaaacg acatggggcg gccgtccctt acaaatcgaa gtcggtcagc
    34981 tagcaaaaca agcaaacgga gccgttttag tccgttatgg agatacagta gtcttaagtg
    35041 cagctgtggc ctctaaagaa gcaaaagata cagacttttt cccattaacg atcaattatg
    35101 aagaaaaaat gtatgcagca gggaaaatcc ctggaggttt catcaaacga gaaggccgtc
    35161 caagtacgga agcaacattg actgcccgtt tgatcgaccg tccaattcgc ccgatgtttg
    35221 cagaaggctt ccgtaatgaa gtccaagtaa cgaacatcgt gatgagtgta gaaacagact
    35281 gctcgccagc tatggcagca atgctaggtt cttctttagc actatcaatc tcagatatcc
    35341 catttgacgg cccaatcgca ggcgtagaag ttggtcgtgt aaatggcgag tacgtcttga
    35401 atccaacagt agaacaagca gaacaaacag atatcgaatt gactgttgcc ggaacgaaac
    35461 aagccatcaa tatggttgaa agcggcgcga aagaagtttc agaagaagac atgcttggtg
    35521 cattgctgtt tggttttgac gctatcaaag agttagttgc tttccaagaa gaaatcgttc
    35581 aagcagtagg gaaagaaaaa atggaagtga ctttactgca agttgatgaa gtattgaaaa
    35641 aagaaatctt tgatgcttct tacgctacaa tgaaagcagc agtaatgact gaagaaaaac
    35701 ttgctcgcga agataatatc gagcaggtga agatcgatat ccgcgaagct tatgctgaga
    35761 aatttgcagg tcatgaagat gaagatcact tgttgaaaga agttaaacaa atcacagaag
    35821 atcttgaaaa agatgtcgta cgtgaattga tcaccatcga taagatccgt cctgacgggc
    35881 gtaaattgga tgaaatccgt ccattgtcat cagaggtcag cttattgcca cgtgtacatg
    35941 gatcaggttt gttcacacga ggacaaacac aagctttatc agcttgtaca ctcgcacctc
    36001 taggagagca ccaaatcatt gatggtttag gggtggaagt cagcaaacga ttcatccacc
    36061 actacaattt tcctcaattt tctgttggtt ctacaggacg tgcaggctct ccagggcgtc
    36121 gggaaatcgg acatggcgca ttaggtgaac gtgcgttagc acaagtaatc ccttcagaag
    36181 aagaatttcc ttatacgatc cgtttagtag cagaagtatt ggaatcaaat ggttcttctt
    36241 cccaagcaag tatctgtgct ggcacattag cattgatgga tgcaggtgta ccaatcaaag
    36301 cgccagtcgc cggtattgcg atgggacttg tttctgatgg tgaaaactat acgatcctaa
    36361 ctgatatcca agggctggaa gatcatcttg gcgatatgga ctttaaagtt gccggtacaa
    36421 aagatggtat cactgcttta cagatggata tcaagattca aggaatcaca gaacaaatcc
    36481 taactgaagc attaactcaa gcaaaacaag cacgtatgga aatcttagaa gaattgactt
    36541 caacgattgc tgctccacgt gaagaattaa gccaatatgc accaaaaatc gaaatgatcc
    36601 agatcgaacc tgctaaaatc aaagatgtta tcggtaaagg cggcgatacg atcaacggaa
    36661 tcatcgatga aactggtgtg aaaatcgata tcgatcaaga tggaaaagta agtattgctt
    36721 cagctgatgc agaaatgatc aaaaaagcta tcaagatcat cgaagatttg accaaagaag
    36781 tcaaagttgg tgaagtttat ctagggaaag ttgtccgtat cgaaaaattc ggtgcattcg
    36841 tcaacttgat caaaggaaaa gatggacttg tccatatttc ccaattagca aacgatcgtg
    36901 tcaataaagt cgaagatgtt gttaaactag gtgatgagat ccttgtgaaa gtaactgaaa
    36961 tcgataaaca aggacgcgta aatctgtcaa gaaaagcaat gttgaacgaa gatggttcaa
    37021 cgaaaaatga agaaaaataa tttaattcat aggaataatg tacttgtgat cgtgaaggtg
    37081 acagggggac aataattatt cgaaaaaagg ggactgtgac aaaagccgtg tcacagtcct
    37141 tttttttcga ataaacggtg ttcaaaagct tgcatctgcg gtaataagtc cagccaagtt
    37201 aaaaacatta ggagctgttt ttatttggct gttcttatta cttgatgcag aacagctttt
    37261 ttacaacctc tccaataaac gatgttcaat cagctgtccc tcgatattag ctcaaaaaac
    37321 ggcaaaatat gaggaactat ttttccgttt gtttctctaa tactcaggtc aaaccgctga
    37381 tttcacaacc tctgattcac ggtgttccag aagcagcttc tacggaaata agctgaacac
    37441 ttttgttaca acttcttttt ttctggagtt tcttggcgca tatttttgga gtccttctga
    37501 ataaagcgta aaataaaagt gagaaatatg gataaaggag ggaaaggaga tgctgaattt
    37561 tttatggtcg ttatttatcg gcggtatatt aggtttgata gctggcgcaa ttttaggaaa
    37621 ggaagtcccg ggaggcgtat ctggaaatat cattatcggt tttttaggta gttggctcgg
    37681 cgaattttta ctaggaccac tgggaccgga actcggcggt ttttatttga taccagcatt
    37741 attgggtgca attttttgcc ttgctcttta ttcatttgtg gcaagacgta tcagagaacg
    37801 tccaaagaaa gaataatttt attcaaataa gttgacactt cagtgtgtta cttggataat
    37861 tagaagcaat ttaggaaagc gggtgtcatg gataagaata tcatctatca ttcaagctta
    37921 cctaaaggat atccatataa caagaaatga gggaaaaacg tggcaacaac gcacaatacc
    37981 aaaaagatat caatggctgg cctgcttgta gcgatgggag tcgtctacgg agacatcggg
    38041 acaagtccgc tttacgttat gaaatcgatt gttgaagata atggcggatt gtcaggaatc
    38101 aatcctgatt ttgttatcgg atcagtctca ttgatttttt ggacattgac tctactgaca
    38161 acaatcaaat atgtcgtgat tgcattgaat gcagataacc atggtgaagg tggaattttc
    38221 tcactctaca cacttgtccg aaaaggtggg aaatatttga tcattcctgc aatgatcgga
    38281 ggagctgcct tactagcaga tggggtattg acccctgctg tgacggtaac gactgcgatt
    38341 gaaggcttgc gaggaattcc gcagtttttt gaccggttcg gtaataacca gaacgtgatc
    38401 gtcattatca ctttagttat tatttttgtt ttattcatgg tccaacgctt tggtacagat
    38461 attgtcggaa aagcattcgg accaatcatg ttcgcttggt ttactttttt aggcgtaatg
    38521 ggattaatga acttcagtca agactggaca gttatccgtg cactgaatcc ttattatgct
    38581 atccagctgc tttttagtgc agataacaaa ttaggcttgt tcattcttgg aaatattttc
    38641 ctggctacga caggtgcaga ggcgctttat tccgatcttg gacatgtcgg caaacgaaat
    38701 attcgtctga gctggcctta cgtcaaaatt tgtttggtta tcaattattt tgggcaggct
    38761 gcgtggttgt tgaatgttta tcaaaaccct gaagcacagc aaatcaagaa cctgaatcca
    38821 ttcttccaaa tgatgcctca aagttggatc gtgatcggcg ttgcttttgc aacagtcgct
    38881 gcagtcattg cttcgcaagc attgattaca ggttcgttta cgctagtttc agaagcaatc
    38941 aagttgaaac tgctgcctcg gttaaagatc atgtatcctg ggaacagtat cgggcaaatg
    39001 tatatcccag cagtcaatct gattttatgg atcgcctgtt ctctagtggt tgtcacattc
    39061 cgaacgtctc atcatatgga agctgcttac ggtctatcga tcactgtgac gatgttgatg
    39121 acaacagcac tgctttactt ttatcttatc caaaatgggc attctcgttg gcttgcatat
    39181 ttagttacct ttttcttcgg tgcgatagaa gtcgttttct ttatctcaag tgttgtcaaa
    39241 ttcttccgag gcggttttgt agccgttctg attggtttga tcatcttagt cgtgatgttt
    39301 atttgggaac aagggaacat tattcgcgaa tcgtcaaccg aggatgtgtc tttgagagat
    39361 tatatcccgc agcttagaga attacgtgat gatacttctt taccaatcta tcagacaaat
    39421 gtggtcttct tggttcctga tatggctgaa gataaagttg gccgacagtt catctattcg
    39481 attttagata aacggcctaa aagagcacga gtctattggt ttgttcatgt ggaagtgacg
    39541 gatgagccat atacgaaaga atatcaagta gatatgatgg acactgattt tattgtccaa
    39601 gtgaatctgt tcttaggttt cagggtccaa caggaaatca acgtatatgt tcgccaagtc
    39661 atccatgatt tgatgaaaca aggccgtttg ccaaaacagc cacaaagata ctctctgaca
    39721 ccagggcgag aagttggcga tttccaattt gtcctgattg atgaagtagt ttccaatgtg
    39781 acaactctag gaaaatggca acgtcaaatc atgcaggcaa aactggcaat caaaaaaatc
    39841 gctacctcgc cagaaacatg gtttgggcta gagtacagcg aagtaaaaca tgaaactgtt
    39901 ccgcttatca ttggaaatac tcggaaaaca tggttgaaag agcggttgtg aaagtagcgc
    39961 tttgacctga actaatgtcg aatgtcagct acttgaacac cgtttatcag aggtcatgaa
    40021 aaagctgtac tgcaacaagc agtaagaacg agcagataaa aacagcttct catgtttttc
    40081 atctgtttgg gcttaatgcc gtagatgcaa gcttttgaat accgttttta tcagaggtca
    40141 tgaaaaagct gtttagcaac aagtaacgca atgattttga agtgataagg agatgtggct
    40201 gaaaaatgcc gcatctcctt ttttattcct aaatatgaat acgcattatt ttcaatcttt
    40261 ttgtagaaaa agggtacaat agaaaaagag aaaggcggga gaatatggtt atcaatttca
    40321 ttattttatt tttgatgatt gcaattactt cattttttgt agcaagtgaa tttgctttag
    40381 tgaaaatcag acgatcaaga ttggaacaac tagaaaagga aaatgtaaag aacgccaagc
    40441 tagctcttca tgttacacac catttagata actatttatc agctagtcaa ttaggaatta
    40501 cgctaaccgg tttgatcatc gggtgggtcg gtgaaggatc tgtcgcggct ttactagaac
    40561 cagtgatcgg taaactacct tttagttcgg ctattagcag tacaatctct gtggcgctgg
    40621 gatttatttt agttacgtat atcgatgtgg ttattggcga actgcttcct aagagctata
    40681 gtatcgtcaa tacggagaag gtcgtcttgt tcgtagttaa accacttcat tatttttata
    40741 aagtaatgtt tccttttatt tgggtattga atcattcagc tgcagggcta gggaagctat
    40801 taggtgtgcg tctcgtatct gaaggagaag agacattgtc tcaagaagag ctgacattag
    40861 tcgcattgaa ttcttatgaa aaaggagagt tgaccaaaga agaatattat tatttggaaa
    40921 acgtgtttga atttgatgat accttggcaa aagatataca agtagaccgt acgtccatgc
    40981 aagtattcga agcttcagaa accgtcaaag aagcgataaa agcttcgatt gaacaaggac
    41041 atactcgcta tccggttatc ttagaatcaa aagacaatgt tttaggttat gtcaccttgc
    41101 cagatttgat caagcaatct tataaagatg accagctgac agtagaacag ttgattgaag
    41161 agccgatcgt aacaactgaa acgatcccta taaaaaaatt attgacgatc atgcgaaaaa
    41221 agggtaagca tattgctatc ttaaaagatg aatacggagg gacaagcggc ttagtgacga
    41281 ttgaagatat tttagaagaa atcgtcgggg aaatccgaga tgagacagat ttggacgaag
    41341 cattgatagc ggaacagtca gatggctctt atatcatctc cggcaaacta acattagatg
    41401 atttccagcg ttattttcat gtagagattc cagagtttga agaaacgaat tttactacac
    41461 ttgcgggctt tgcttctagc cgatataaag aaataaaagc aggaacaatc attgagattg
    41521 catcattccg tttcacggta ttagaatacc agcatgcaca tatcgattat ttcaaagtag
    41581 agtccacgga aagaaaaaca gaataaaaga aaaaaggctg tgacattttt tgtcacagcc
    41641 tttttgttat ctaaaaaacc tgttttcggt aaacgaagaa gatattttca ataaaagttt
    41701 tcatttttag ccgcaacgat ttcttttaat caaggctatc ttgcttctgc atgttctaat
    41761 gtgaaatgtt cctcttcacc catgtgtttc aattgtttca tcgaacgcat ataagagtaa
    41821 agcaacacgg caacagaacc gatccaagct aaaggagaag ctgctgctgc tcctgggtat
    41881 ccccacattc ctgtaagaac gatagctgca aaagaacgca taagcaattc catcataccg
    41941 gcgatcgtag ggatcttgct ttgtccaagc ccttgaagtg tgtagcgtaa aatgaacagg
    42001 actgctaaga tccagtaaag agacccattg atattgaagt aggtttgtgc taattcaaat
    42061 acacgtgttt ctgatgggct aacaaacaat tgaacaaaga aatgaccgaa gaaaatgacg
    42121 atagcacctg ctaagagact aaatccgaca ctcatcagta aagtttgacg taccccttgc
    42181 aagattcggc catattcttt cgcaccatag ttttgtgcag tgaaagttgc cattgcaata
    42241 ccaaatgaca tcatcggctg atttgcaaat tggtcgatac gaccagcagc ggcttgagca
    42301 gctacgacat ctgtccctag actatttagt gctgcttgta acacgatagc accaacagcg
    42361 atgatcgaag attgaaacgc cattggcaaa gcagcattta ggtgtacagc aaactcttct
    42421 ttttcaaatt tgaaatcttt tttgcgtaac tgtaacaaag gcattttttt cttgatatac
    42481 actagacaca gtacgctgga agaaacttgt gcgattactg tagcaatagc tgcaccttcc
    42541 acacccatgc caaaatagat aataaagatc aaatcaagta cgacgttgat gatgaccgca
    42601 atgatcagaa agaatagtgg tgtgcggctg tcaccaagtg cgcgaatgac attagaaagc
    42661 aaattgaaac tgactgatgc aaagatccct aataaaataa ttgaaataaa tgtttgtgct
    42721 tgatcaagta tttcaggagg agtttgcatc aattgaagca tcggacgaat aaacaggaga
    42781 cttaggacag ttaaaatcac agtgacgaca agactaatga caacactagc agcaaaactt
    42841 ttcttcagac cccgataatc ttttgcaccg taacgttgtg cggtaataat ggctaaacca
    42901 gctgttaaac cttgggcaaa gccaatgatc aaaaatgtca ggcttccagt tgcaccaacc
    42961 gctgccagcg catttttacc tagcgtctga cccacgatga tcatatcgat catattgtag
    43021 aactgctgaa aaacatttcc gatcagtaaa ggaacagtga acatcaaaat cagtttagcg
    43081 gggcttcctt ttgttaaatc gcgcatcttt taaactcctt atatctttaa aatttagtta
    43141 gtagtatata gcgtttatcc tgagaatacc aattagaaat caatgataat ttatgaaact
    43201 ccataaaaag aagccaagaa ttgagtcaaa gaatcaacaa cttggcctgg tctgtaaaat
    43261 aagggacatc cacgtttatc tatcacctta atattgtcta atctcacttg gtaaaaggat
    43321 cgtttctctc gtaccgtcat cataggcgta tacttgagca ggaaattggt tcgaataggc
    43381 aaacggcaaa tcaatatcca tttccacatt gcttcctgct tgagaaaaat gcatcgtcac
    43441 ttttccacga ttttcgatca aatcaaaggt taatatattt tctaatggaa tgactccctt
    43501 aagatctagg tcaataataa accatatact gtcaatcaat tcatctggca aacttgatac
    43561 gacaccaact gaagcgtaac ggttgcggct gctatcaaaa ctttcaaaca tctgtttaac
    43621 ctccttcgaa tcaacgaatg ttttattttt ataattaatc ctaggataaa ctagaaatac
    43681 ttacttcaac gagggttcat tctaataaag aatcaggaaa aatgcaacaa taattgaata
    43741 ctttttttca aagtataaat ttttataaag gtacgataaa agtatgcgag gaaaagcttg
    43801 gtaaattagg atttttcgtt tgtaaagcca tttacaaaag tggaagcccc atatgaaaat
    43861 aaacgattag aaataaaaaa ggcgtgttaa aagctgctga cccgccgctt ctaacaccac
    43921 ctgattgttt cagtattatt cttctgttga accgatcact tctggttcgc caccttcacc
    43981 tgtgctttct tcttcttcac tttgagcgac tacagcagcg atttgctctt cactgtcggt
    44041 cacgaatttg taatcgtcgt tttttggaag atcggctact gtaatagaat cacctaattc
    44101 caagtttgtc acgtcaactt caattcgttc aggcaatttg tctggtgtag cagatacgac
    44161 tactgtatac aagttttgag ctaacactcc accagattta gcacccactg attcgccaac
    44221 aagaacgact tctgtttcga cttctgtttc ttccgacatg tttacagata gaaattctgc
    44281 atgttcgaaa tgattggtaa aagtgttcgt ttggatcttg tgaaccaatg tattgacttt
    44341 ttgtccatcg atgtccatcg tgatgactgt gttcgctcca tgttcacgca acaatttgct
    44401 tagtgtcaaa ccatcgaatg agataggggt actttctact ttatacccat aaacaacagc
    44461 tggaactttc ccttcgtgac gaagtttgtt tcttaatgaa cggggacgta cttctctttt
    44521 acttacttct aatgatactg acataaccaa aattcctcct taaaatgtga ctgtctgctt
    44581 tggtaacgga cagattttat ttaagtgaat tctaaaggct aatctcgtgc acatcatcga
    44641 aggcagggcg cttaaaaaag cgcaaaagga gagatgcgcg catctcccct tagaaagtca
    44701 ggattcaact tttctccacc aggtcattac gctgtgtatg agaaatccaa ttcactttac
    44761 tatttaaccg taacgtgaac tgttaattaa gtcaaggaat aactatgatg atgtatttgc
    44821 aagcaagaat attcaaggta taattaatta gtagtaataa gaaaggaaac agcatgcgtt
    44881 tagataaatt aatagaagaa aaattagaaa cgacacgcaa ggaaatgaag cggctgtttg
    44941 ctttgaagca agtgatgata gatggcacag tcgaatttcg acaaaatcga aatgtagata
    45001 gtttactgca tcaaatcgaa gtagcaggtg aacacttaga aacaaatgag tcctattatc
    45061 ttctcaataa acctgaaaaa gctgttacag ctgtatcaga tccagaaaag acgacagtaa
    45121 tcgatctgat tgcaagtgcc gatcgtttcc aaccattata tccagtggga agactagata
    45181 gagatacaac aggactattg ctgatcactt cgaatggaca attgggatat gaaatgctac
    45241 ttccagaaaa aaaggtttca aagacttatc aagtagttgt gaacgaaagg gtgacaccgg
    45301 cagacgtaac agcatttgaa aatggaatcg tattcgctga tgggtatcaa tgtaagccgg
    45361 ctgatttaaa aatactcaaa gcagacaagc accaaagtac ggttttattg acgatccaag
    45421 aaggaaaatt ccatcaagtc aaaaagatgt tcttagccca aggaaagaaa gtgaccgcat
    45481 tgaaacggct aagcatggga ccattggaat tagatgaaca gctaggagta ggcgagtatc
    45541 gatcgttgac attagcagag atgaaaaagt taagtattta ttttaaatag gaggtcaaaa
    45601 agatgaaata taaaacttta ttgtttgatg tagatgatac attgttagat tttcaattaa
    45661 ctgaagccaa tgctttaagt gctttgtttg cagaacaagg aatcacattg acaccagaaa
    45721 tcgaaaccag ctataaggct ttgaatcatc atttatggca ggagtttgaa aaaggcagac
    45781 tatcacgaga agaaataata ggcagtcgtt ttgggttact tttccagcaa tttgggaaaa
    45841 cagtagatag tgatcaaatg gaaaaacgct accgccacta cttgaaccaa ggtcatgatc
    45901 ttgttccagg aagtctagaa atcctgaaaa aggtccatcc gcatgctgat ctttatattg
    45961 tgacgaacgg tgtgtcgcac acgcaacatc ggcgattaac agatgcagga atgcttgatt
    46021 acttcaagga tatctttgtc tcagaagctg tcggagcgca aaagccgatg aaagaatttt
    46081 ttgatcatgt cttttcccac attcctaatt ttgataaaaa gcaaactgtg atcattggtg
    46141 attctttgac ttctgatatc aaaggaggaa atatggcagg gatcgatacg atttggttca
    46201 atagaaataa attaccagaa atcgaagaaa tccagcctac ttatcgaatc gattcattag
    46261 aggaacttta ttcattattg gaaattgaaa aggattaatt ttcagaaaaa tatagcattt
    46321 tcgtgttttt tcgctataat agattagaat gaaaaaacgg atacgaaaga ggttttagtc
    46381 aatgacaaaa agcaagccaa ttatcattgg tgtgacgggt ggatccggaa gcggaaagac
    46441 aagtgtcagc cgtgcgattt tcaacaactt cccggaccat tccatcatga tgcttgaaca
    46501 agattcttat tacaaggatc agagccattt gagttttgaa gaacgattga acacaaatta
    46561 cgatcaccca tttgcctttg ataatgatct gctgattcag catgtaggcg acttactgaa
    46621 ctataaagcc attgaaaaac ccgtgtatga ctatgtagcg catacaagaa gtcaggcaac
    46681 gatcattcag gaaccaaaag aagtgatcat tctagaagga atcctgattt tagaagacga
    46741 acgtctgcgt gacttgatgg atatcaaagt atacgtagat acagatgatg acattcgtat
    46801 cattcgtcgt atcaaacggg atatggaaga acggggacgc acattggact ccgtgatcga
    46861 acaatatttg acagttgtta aaccgatgta tcatcaattt atcgaaccaa cgaagcgcta
    46921 tgcggatatc attgttccag aaggcggaga aaaccacgtt gctattgatt tgattacaac
    46981 aaaagtagct agtttcttaa accataaata gtgcgcagcg aaacagttga acggactgcg
    47041 accgtttgaa aagcaaggat tctgcttttt gaacagtcac cagccaactg tttttttatt
    47101 tataacaaga ggttgtgaaa acagcatctt gacctaagta ttaaaaagaa gaaacggaaa
    47161 atagctgttt atattttacc gttttttgag ctaataccga aggtcagctg attgagcacc
    47221 gtgaagtaga ggttgtaaaa aagctgtctt tgcatcaagc gataagagca tccaaataaa
    47281 acagctcctc acgtttttcg ttgggttggg cttattatcg tagatgcaag cttttgaaca
    47341 ccgtttaacg agaggttgta acagaagtgg tcagatgcaa taaataagaa gaaacttacg
    47401 aaaattattt ctcgaatttg tgtgagattt cgacttattt ttttgaagaa gctcttttgt
    47461 cgcaccccc
//
LOCUS       DAZULR010000022        46219 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.022, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000022 DAZULR010000000
VERSION     DAZULR010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 46219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46219
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.022"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            160..840
                     /locus_tag="ACG8ZV_001358"
     CDS             160..840
                     /locus_tag="ACG8ZV_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFS4996709.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            930..1964
                     /locus_tag="ACG8ZV_001359"
     CDS             930..1964
                     /locus_tag="ACG8ZV_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HFS4996710.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            1978..2313
                     /locus_tag="ACG8ZV_001360"
     CDS             1978..2313
                     /locus_tag="ACG8ZV_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996711.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            2297..4777
                     /locus_tag="ACG8ZV_001361"
     CDS             2297..4777
                     /locus_tag="ACG8ZV_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996712.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            4833..6392
                     /locus_tag="ACG8ZV_001362"
     CDS             4833..6392
                     /locus_tag="ACG8ZV_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4996713.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            6389..7753
                     /locus_tag="ACG8ZV_001363"
     CDS             6389..7753
                     /locus_tag="ACG8ZV_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding oxidoreductase"
                     /protein_id="HFS4996714.1"
                     /translation="MKIVIIGASHEGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            7924..8994
                     /locus_tag="ACG8ZV_001364"
     CDS             7924..8994
                     /locus_tag="ACG8ZV_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4996715.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            9009..9677
                     /locus_tag="ACG8ZV_001365"
     CDS             9009..9677
                     /locus_tag="ACG8ZV_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4996716.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            9697..10275
                     /locus_tag="ACG8ZV_001366"
     CDS             9697..10275
                     /locus_tag="ACG8ZV_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFS4996717.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            10676..11587
                     /locus_tag="ACG8ZV_001367"
     CDS             10676..11587
                     /locus_tag="ACG8ZV_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFS4996718.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(11965..12882)
                     /gene="rnhC"
                     /locus_tag="ACG8ZV_001368"
     CDS             complement(11965..12882)
                     /gene="rnhC"
                     /locus_tag="ACG8ZV_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HFS4996719.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELDKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            13084..13521
                     /gene="zapA"
                     /locus_tag="ACG8ZV_001369"
     CDS             13084..13521
                     /gene="zapA"
                     /locus_tag="ACG8ZV_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HFS4996720.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            13579..14127
                     /locus_tag="ACG8ZV_001370"
     CDS             13579..14127
                     /locus_tag="ACG8ZV_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HFS4996721.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            14242..16602
                     /locus_tag="ACG8ZV_001371"
     CDS             14242..16602
                     /locus_tag="ACG8ZV_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HFS4996722.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKIENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNTYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            16689..17003
                     /gene="trxA"
                     /locus_tag="ACG8ZV_001372"
     CDS             16689..17003
                     /gene="trxA"
                     /locus_tag="ACG8ZV_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HFS4996723.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            17185..18963
                     /gene="uvrC"
                     /locus_tag="ACG8ZV_001373"
     CDS             17185..18963
                     /gene="uvrC"
                     /locus_tag="ACG8ZV_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HFS4996724.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMVKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            19108..20007
                     /locus_tag="ACG8ZV_001374"
     CDS             19108..20007
                     /locus_tag="ACG8ZV_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4996725.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            20000..21262
                     /locus_tag="ACG8ZV_001375"
     CDS             20000..21262
                     /locus_tag="ACG8ZV_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4996726.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPIRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            21423..23321
                     /locus_tag="ACG8ZV_001376"
     CDS             21423..23321
                     /locus_tag="ACG8ZV_001376"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042132 - fructose 1,6-bisphosphate
                     1-phosphatase activity [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HFS4996727.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(23651..24370)
                     /locus_tag="ACG8ZV_001377"
     CDS             complement(23651..24370)
                     /locus_tag="ACG8ZV_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HFS4996728.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLVEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     misc_feature    24560..24607
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF03071"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="sodium ion sensor (DUF1646 type); this
                     cis-regulatory element may regulate processes involved in
                     with the transportation of sodium ions; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF03071"
     gene            24707..25039
                     /locus_tag="ACG8ZV_001378"
     CDS             24707..25039
                     /locus_tag="ACG8ZV_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996729.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            25026..27029
                     /locus_tag="ACG8ZV_001379"
     CDS             25026..27029
                     /locus_tag="ACG8ZV_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HFS4996730.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            27048..27518
                     /locus_tag="ACG8ZV_001380"
     CDS             27048..27518
                     /locus_tag="ACG8ZV_001380"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HFS4996731.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            27539..28123
                     /locus_tag="ACG8ZV_001381"
     CDS             27539..28123
                     /locus_tag="ACG8ZV_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HFS4996732.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            28138..29124
                     /locus_tag="ACG8ZV_001382"
     CDS             28138..29124
                     /locus_tag="ACG8ZV_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046961 - proton-transporting ATPase
                     activity, rotational mechanism [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HFS4996733.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            29114..29425
                     /locus_tag="ACG8ZV_001383"
     CDS             29114..29425
                     /locus_tag="ACG8ZV_001383"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HFS4996734.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            29447..31228
                     /locus_tag="ACG8ZV_001384"
     CDS             29447..31228
                     /locus_tag="ACG8ZV_001384"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HFS4996735.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            31221..32597
                     /locus_tag="ACG8ZV_001385"
     CDS             31221..32597
                     /locus_tag="ACG8ZV_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HFS4996736.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            32604..33239
                     /locus_tag="ACG8ZV_001386"
     CDS             32604..33239
                     /locus_tag="ACG8ZV_001386"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HFS4996737.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            33269..34624
                     /locus_tag="ACG8ZV_001387"
     CDS             33269..34624
                     /locus_tag="ACG8ZV_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HFS4996738.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(34816..36210)
                     /locus_tag="ACG8ZV_001388"
     CDS             complement(34816..36210)
                     /locus_tag="ACG8ZV_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFS4996739.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            36302..37273
                     /locus_tag="ACG8ZV_001389"
     CDS             36302..37273
                     /locus_tag="ACG8ZV_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HFS4996740.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            37270..38052
                     /locus_tag="ACG8ZV_001390"
     CDS             37270..38052
                     /locus_tag="ACG8ZV_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HFS4996741.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(38221..38592)
                     /locus_tag="ACG8ZV_001391"
     CDS             complement(38221..38592)
                     /locus_tag="ACG8ZV_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFS4996742.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            38726..39169
                     /locus_tag="ACG8ZV_001392"
     CDS             38726..39169
                     /locus_tag="ACG8ZV_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFS4996743.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(39212..40021)
                     /gene="yidA"
                     /locus_tag="ACG8ZV_001393"
     CDS             complement(39212..40021)
                     /gene="yidA"
                     /locus_tag="ACG8ZV_001393"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HFS4996744.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(40040..41407)
                     /locus_tag="ACG8ZV_001394"
     CDS             complement(40040..41407)
                     /locus_tag="ACG8ZV_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFS4996745.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(41391..42221)
                     /locus_tag="ACG8ZV_001395"
     CDS             complement(41391..42221)
                     /locus_tag="ACG8ZV_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HFS4996746.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLEDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            42384..42821
                     /locus_tag="ACG8ZV_001396"
     CDS             42384..42821
                     /locus_tag="ACG8ZV_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HFS4996747.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            42897..43517
                     /gene="rpoE"
                     /locus_tag="ACG8ZV_001397"
     CDS             42897..43517
                     /gene="rpoE"
                     /locus_tag="ACG8ZV_001397"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HFS4996748.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            43706..44212
                     /locus_tag="ACG8ZV_001398"
     CDS             43706..44212
                     /locus_tag="ACG8ZV_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HFS4996749.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            44229..45128
                     /locus_tag="ACG8ZV_001399"
     CDS             44229..45128
                     /locus_tag="ACG8ZV_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsiV family protein"
                     /protein_id="HFS4996750.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            45215..46099
                     /locus_tag="ACG8ZV_001400"
     CDS             45215..46099
                     /locus_tag="ACG8ZV_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFS4996751.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
BASE COUNT        15236 a         7977 c         9766 g        13240 t
ORIGIN      
        1 ttaataaaaa aggaagaata ttcatgtaaa cgattttatt gtttttttct cttttataca
       61 aaaagggtca taatttcaag taagcggatg aattcatgag gattttttgc atactgtctc
      121 tactatactt aggtcactaa gaaaaaggag tgatttatta tgaaaaagaa catgattggg
      181 acattattac tttcaacact tcttctaggc ggcttggcaa caccagcttt tgctgagggt
      241 caagcgactt caaaaggaga tattaccttt actgaaccaa caaataccgt ggagcctctt
      301 aaccctactg atccttcaaa accagtagag ccagcagatc cggaaaatcc agcaactggc
      361 cagacaggtc ctttaacact ggatgtagtt cccgaattgc catttggtac acacgagatt
      421 gaaagcggaa caaaaacgta tcaagtagac gcttcaaaaa acgatacacc ttatctccaa
      481 gtatcagatc gtcgaggtgt aggtgcagat ggccaagcac aagggtggaa cgtgacagtt
      541 tcggtttcag attttgtaaa cggttcacaa gttttgcaag gcgctgaatt agattttgga
      601 acatccactg ttaaaagtac gtcagataac gaatccactg gaccaactag tcaaactgta
      661 actgggttga gtaaagcaag tgcagcgaca ccaatattta cagcagcaaa agatcaaggt
      721 ctgggaacat ggctttctgt ttatgatcca gcaaatatca cactgaaagt gccgaaagca
      781 gcagctggaa cattcacggc tgatttgact tggaacctcg tggctggccc agtagcatag
      841 agtatgaaat aaattcaaca aactgcggtg aaaatactat aggtgaagga ttttttaccg
      901 cagttgttgt tgaaaggatg tggtggacaa tgaatcaaag taaacgactg tttgtttcgt
      961 ttttttctat tttaagtcta tttttcattt ttccgtcaat cagccaagca aaggattcag
     1021 caggagactt tggaatcaaa ccggtatttc cagagaacca aatagataaa gcaatcggtt
     1081 attttgattt attagtggca ccggaacaaa atcagacact agaagtaatt atcagcaatt
     1141 cttcagatga agaacgaaca tttgaggtct ctgtcaatcc ggcggtaacg agtgatggtg
     1201 gaacgatcga ttatagtcaa aaaaacccaa cgttagatga gacattgccg tttgatgtcc
     1261 gtgacgtttt gctcattgcg aaaaaggaaa tcaatgtatc agcacatgca gaaacaactg
     1321 tacctataga agtgaaaatc ccagcaaaaa gctttaaggg acgtgtatta gcgggtattc
     1381 atgtttcacc taaagaagaa gctgaaacag aaaatgctac agaaggagca caaatcaaaa
     1441 atcgtattgc ttataatctc gcagtcgttt tacaagaaag tcaagagacg atagaaccgg
     1501 atctgaaact tttatcagga gatttggacg aggtcaacgc aaagccaact gttcagcttc
     1561 gtttccaaaa tcctcagcct aggattatca gcaatttgat atttacgagc aagatctttt
     1621 atgaaaatca gctttatatt gaaaatacgt ctaatgcatt tttagttgca ccaaattcga
     1681 attttcactt gaatcttgat ttagctggtg ataaagcaaa agccggcgat taccgcgcag
     1741 aaatcatagc aaaatcaggc gacagtaatg aatggcgatt tacacaaaac tttacgatca
     1801 aaaaagaaaa agcacaaaaa gtaaatgaaa attccgtttt tgcagtacaa gaacaatctt
     1861 tcccatggct ttatgcagga ttggttgctg cagttctagt gttatggttg attttgctgt
     1921 ttttgtgggt ccacaagaaa aagaaaaaag gagaaacaac atgatgaggt gatttcgttg
     1981 aaaacatcga tcttattggg agggattatt gcaagtttgc tgttcttcag ctggcaagag
     2041 ccagtccaag cagataccaa aagttcaggt acgattacat tttatgatct aagtccaatt
     2101 ccgcatccaa gtggttcagt caatggcgca tcaaaacagc agacacagct accgatttat
     2161 aaagaatcta atcaacatgg cgtattcccg gagacgaatg aacaaaagat ccgttttctt
     2221 tatttgatca ttggtataga attatggctt cttgcgtggt tgttgttatg gagaagaaag
     2281 gaaaaggagg atgaacatgt tgctacaaaa taaattttca ttttttcgct ccttcttttt
     2341 tacttcgctt tttgttttaa gtatatttat cttttcacct tcggcagaag ctgttggagc
     2401 aacgcctcct gccatttctt atgatccata cacgtatgaa aatatcgtac ctccaaatgg
     2461 tggacgtagt gcagtcaatg gcgggaagct tgtccaacta actggggcta accaattgcc
     2521 taaattgact gctacttatt tgaacgatgg ttcaaatgat ccttggaaag gtggcacggt
     2581 ccgttttcat tgggaaagcc atgtgaaact aacaaatgta cttgatttgg tgaatatcac
     2641 tgcacaagga tttgcatttg tggcgatcat caatttgccg gaacatgtat caagcagtga
     2701 tgtattaaaa gcaattgact ggaacaacgc ctacttgtat attgccggtg cccccatcaa
     2761 ggttactagc ggaagtttat tatcagcagg aagccatacc ttgcgttttg ggatggggtc
     2821 gtgggataca aatactctat tgacagatat tattgctatt attacgcgag gcgaattcaa
     2881 cgtggacgat atcccgcttc aatttgatgt tacagctaat gtcgcgaaga tgacagaaaa
     2941 cggagataaa tatgatacga gtccaaacaa aattttgacc aagggtaaat tacaaccttc
     3001 tatgtctaaa aaggccgttt tttctgttga tttttatgat tcgaataata ttatccaaga
     3061 tcgtatgttc aattcgattt tagctccagc tgcaggtaga ttttatccta aattaactgg
     3121 cggaaacttg aatccaggag catatgcatt ttctgcaagt gcagagataa atacgtggaa
     3181 tagttacatc tcaccaagtg attcaacagg aaaatataat acatttgctg ataccacaga
     3241 atacgtggat ggaaataacc agaaccttcc aggctctacc aatagtcgga cattgacgat
     3301 ggggctgact gaaggacgtt ttgatcagtt gccatttagt cgctttgatc gcgtagtcaa
     3361 ctattttaca ggaaaaaacg ttacacaagg agcaatactg actcatactc cagcaagcac
     3421 aagtggattg aatcagacag ccaatatcgt gtacagtggg aaagatgcgc aaggcggatt
     3481 gctttctcct gttgctttaa aggtattgga gcagtacaag ctagacggaa cggttttacc
     3541 aacaaactta acagccgata gtcagtgggg aaagctcctt tcttctgcat cgtaccaagt
     3601 cacggccaat tggtcagcaa ctgaactaaa aaagggttcg atccattaca ggctttattc
     3661 gaaaggaacc caaaaattag cgacaggatg gacagatcaa cttttccaaa cgatccaatc
     3721 aaataacggg ggtgtaaata cagctacttc tacactacct gcattggctt cagggcaata
     3781 ttattttgat tatcgcttgg tggacgatgt acttactaac atgtatccgt cttttgcgta
     3841 caaatggcag tctgaacaag ctggaatcac cactcttcct caaataacag tggctaattt
     3901 tccatctgtg agtgcagata gtcagctaaa aaaccttagc agacaacctg agacaggaga
     3961 tcccctgtct gctctatcag gagatacgat tcaagaaaat gtgacattca cgttaacaaa
     4021 atctggggat gcgataaccg acaaaaaaat cacgatctca cttcctgaaa atactactta
     4081 tatcaatggt tccttaaaat taaatggtac aactatcgca gataccggca ttcaacaagg
     4141 agtttctgtc ccagcagatc tattgagcaa aataggagat accattcatc ttacttacaa
     4201 ctatcaatta aatactgtag atacttcttt acaatccgtc agcatactga caaaggcagc
     4261 tgtactttcc agcaatatta cattagcaga tggtgctaag cttcctaacc cagttgtcca
     4321 aacatctgct aaaacaattc ttgtccccaa acaagaatta acattagtta atgtaccaga
     4381 tgattttaca tttggtaacg atctccccaa accgttgaag acaagttatt atgaatcaaa
     4441 aggcgatttt tcttttgatg tgcgggatac tcggcttcca agcacgtctc cttggcaact
     4501 gacaggtaca ttgacttctt tatttaagaa tgatcaaggt caagaattaa gcggaacaaa
     4561 attatacttc aatcattctg gatcaaagca attgattcag caaggtcaaa acacgttgat
     4621 ttatgagagt gatggaacag ctaaaggaga ggttctcgtt gactttcccg ataccgatgg
     4681 tttactctta gaggtaaata gcagtacgaa tgctcaacct ggcgcaacgt atcaaggcat
     4741 ggtcacatgg gaactgacag ctgggccaac cagctaagtg attagaattt gtatggatct
     4801 gtgataactg tcacagatcc tctttttcaa ggatgagaag gaaacttctg ctgttaaaat
     4861 cagaaatgct tgaaggagtg gacttggaac ttttcagttt gcttgaaaaa aatgaacaac
     4921 ggcaaatcaa acttttccaa cttttattag aggaaaaagg agaggtttcc gttaataacg
     4981 tacttacccg cttatcagtt gatcgggcta ccttgaaaga agatctgttt tatttacaag
     5041 ctaacttgga aaatatcaaa caattggaaa ttgttatcca agaagggaat attttattaa
     5101 tcagacatgg aaatatagca gcagtcgatg tttattatca ttgttacttg cgctattcta
     5161 caaaatatca gatacttctt tatctgttgg aaaatggctc atttgatcgg cagaaacttg
     5221 tcatggaact taatatcagt tcggctactt tgtctcgcag agtgaaggaa ttaaatgatt
     5281 ctttaaatga gtttcatctg aaaataaaaa gcgggcggct gaccggtcca gaaagtcaaa
     5341 ttcgttattt ttatttccaa ttattttggt ttggacgtcc ctatcttgaa aacaaaaaag
     5401 aatacagtga tttatcagga aacacttttt tagatctgct gcaaaaagag tttagttttg
     5461 ctattacaga agaaggacga ttgaaatttg aaatatggct ttccattatg aagaagcgaa
     5521 tgcgctgtac gaaaaaatcc aaaccagatt atagcaatct tcctgttgga ttgtttcaaa
     5581 cgacacaatt tttattggac ctccatacat ttttgacccg ttacttcttt caatatgcct
     5641 ttccttggaa tcaaaatgaa acgttggttt tttatctttt catgatcagt aactttacat
     5701 tagatacaca taactcgcat gtccaggagt ttttgataag cgaaaaatac aaagacgacg
     5761 tagtagctca attgaatcga acgtttaaac aatcgataga agaatatttc tctttttatg
     5821 tttttccaga agagatttcg caaaagattg cgttgacagt gatgcaaaat cacgctcatt
     5881 ttgcctattt tagaggatgg atgaatattt ttggccaaga aggattaaaa cagcggttaa
     5941 ctgaagtaga agataaacaa ttcctggttt tatgtgaaag attggtcaga caaacatttg
     6001 ctattgttga ttttactgaa gtagacgagg aaaatgcccg ctttgaatta tttgctcgct
     6061 atgcatctat tttacggacg ctgatcaagc agttagaatt acgtctgcaa attgcttatg
     6121 atcttcctta tgaaaggcta atggcggata tcgtgaaaga aatcatccag gaacaattgc
     6181 tgaatacgat caaatatgat ttagtcgaat acgagaaaga aaagcagtat gatatcattt
     6241 tgactagcca attgaaagag tacccgtcac agaagtccgc taaagttttt gtattcacta
     6301 gcaacgaata taattatgat ttcccctatt tgaaccaatt tttaaaagaa tgttatttag
     6361 aaaaattgaa tttaaggatg aataaaacat gaaaatcgtg atcattggtg cttcccatga
     6421 aggcatcaca gctgccctaa atctaagaaa acttcaaccg aaagcagaag ttttactgat
     6481 cgatgaagat cataaagatg gactaggcta tgtttcaaat ggaatcaacc tttatttaaa
     6541 aggaaagata cgtagtttag ctgaagttgc ccataacatg cggactcttc aagaaagtgg
     6601 ggcaaaactg atcaccgaat ggagagtaac tgaacttgat ccagacaaac atcagctcat
     6661 cctcgcatcc aaagaaggaa aaaacgagac cataacctat gataaattaa tcgtagcgac
     6721 aggttcctct cctgtcacct tgtataaaca aattgaagct gaaaatgtct acacctataa
     6781 aaatctagtg caatctaagc aagtacttgc cgctttaaaa gaagcaaaag aagtagtgat
     6841 cttcggtgct ggttacattg gattggaatt agcagatgct ttgagaaata aaggatacat
     6901 tattcatcta gttgattata tgccgaatgt tttatcaaga tatttcgata aggatatgat
     6961 caacagtttt caaaatcagc tgcaaactaa gcaaataaat ttttatccaa atgaattctt
     7021 gatcgattgg aaaaaatcag aagagaaagt agtatccgta caacttctgt ctcaaacaat
     7081 aaaggcagat atggtcattt tttctgccca aactcgtcct aatacgacat tgttaaaaga
     7141 aaaagtggct ttgtatgagg atgagactgt gatagtcaat gaatatctgc agacaagtga
     7201 tccggacatc tatgcgattg gagatatcgt cccagtcagt tttgacaaaa ataaacggca
     7261 tctcttttta cctttagtta ctcgagctgt acatatggca agagcagtag cgctaacttt
     7321 gagtggtcag ccaaccgctt acgacctcag acaaaagata acagcagcag tcattataga
     7381 ctacttttta ggaactgtag ggctgacaga agatgaagcg ccattcttgg aacaaaatac
     7441 cggttcgtgt tcaggagaat ttgatctatt tccacaatac gacgaagaaa acaaaacagt
     7501 aaatgcaaag ctgatctacc atccggatac attagaaata attggcggac agctgataag
     7561 ccaagaattc ttattatcag atttgaacct gcttgcggat atcgtgaaac acaaaactac
     7621 gattccacag ctagcagttg aggattttgg atttctgtct gaatacacct ctcgttttca
     7681 ctacctcaat gagttagctt ttaaagtact agctaagaga gcaaatagca atagagtaga
     7741 taaaagactg tgagaaatat cacggtcttt tattgtgtgg ggatataata aatattaatc
     7801 aatcgagaat aaaaaattca tataatgaaa tagcggaaga attttttgag cataatattc
     7861 gccaaaaatt tatcaagtga taaaattgtt gtataaaatg attatttcag gaggaggagt
     7921 taaatgtttt tagcattaaa tgaaattatg cattcaaagt tacgttatgc gttagttgca
     7981 ggggtgatgt ttttgatcgc ctacctggta ttttttttga ctgggttagc ttatggctta
     8041 gctcaagata atcgaacagc agtcgacaag tgggaggcag attcgattgt gctttcgaaa
     8101 gatgcaaatt caaatctagg gatgtccatg attactaaga agatagcaga agaagtcgaa
     8161 ggtgggaaag tggcgtatct tgcccaaaca cctggagtcg tgactagtaa agacagtaca
     8221 gaagaaggaa aaatcaatgt tagcttcttc ggtatcgata aaaatcaatt catcatgccc
     8281 aatcttgttg aaggaaaagc ttttgataac gatgatgagg cagtaggcga tattagtttg
     8341 aaagaagaat atggtctagc cataggagat acagttaagt tatctggtag tgacaagacg
     8401 tttaaactaa ctggctttac ggatcatgcc aaattcaatg tctcaccagt tctctataca
     8461 accatcaatg cttaccaaga aatccgcttc gaaaaagaag atacaagtga aaatgcacgg
     8521 attaacgcaa tagttgtcag aggtaaaatc agtaatttac ctgaagattt agaacagatc
     8581 aaaatttcta aattcatcaa tgaattacct ggatataatg cgcaagtatt gacttttgga
     8641 tttatgatcg gatttttgat cgttattgcg gctattgtga tcgggatttt catttatgta
     8701 ctgacgatgc aaaagattaa tatctttggt gtaatgaaag cacaagggat cacaggagga
     8761 tttattgcgc gttctgtagt ggcacaaaca ttcattttat catttgttgg tattcttctt
     8821 ggtctattag gaacagtggg aacatccctt gttctacctg atgcggttcc attccaaagc
     8881 aattggctgt tttttggcgt cattagcttg ttgatgttag tagtagctgt gttaggcgca
     8941 ctattttctg ttcggacaat cgtaaaaatc gatccgttga aggcaattgg ataagaagga
     9001 ggaagaacat gaaagcaata gaatttaaag aagtagaaaa aagtttccaa gatggcgacc
     9061 aagtagttaa agcattgaaa gaaacaacca tgagtatcga taaaggggaa tttgttgcaa
     9121 tcatcggtcc ttctggttca ggtaaaagta cttttttgac tttggcaggc ggattgcaga
     9181 cgcctagcag tggctctgta tttatcaatg atcaagaatt cagtaatcaa aaagaaagcg
     9241 aacgcgttaa actacgtttt aaagaaattg gctttatttt gcaagcttcc aatctggttc
     9301 cttttctgac agtaaaaaag cagttattat tagtagataa gattaaacat gaacatcgtc
     9361 aaaaagaagc aaacgaatta tttgagcagc ttggcgtgga taagttgatc aacaagtatc
     9421 cagaagaact atctggtgga gaacggcaaa gggtcgcaat cgctcgtgca ttgtacaatg
     9481 atccgtccat tattctagca gatgaaccaa ctgctagttt ggattcagaa aaggcacgag
     9541 aagtagtcga tatcttggca aaagaatcaa aagacaaaaa taaagcaacg atcatggtta
     9601 ctcacgatac acggctgatt gacaaatgcg atagaatatt tatgatggaa gatggtgtat
     9661 tgaaagaaaa agaataacca aaaagcaggt ggaaaaatgg tccatcgata caacaaagat
     9721 acacagcaaa aaattttgaa agaagcgact gacttgttta tgtccaaggg atatctcggc
     9781 acttcaacaa gagaaatcgc acaaaaagtt gggatcaccc agcccaatct ctatcattat
     9841 ttcggtgata aagaaaaact atatacggca gttttagaaa accacttaaa agatgttgga
     9901 aaagctttga gagaaatcgt tcaaacaagc gaaacgggat ttcaagtaac cttgacaaaa
     9961 atggcgcagt ttttgattga gacacatctg gtcgatttgt ttctgatgct tcacgatctt
    10021 gaaagcaatc tttcaaagga aacaagagat catcttttct ttctatggaa gaaaaattat
    10081 cgtgaacctt ttgaagaaat cttttcagca aaccaatctg tgctaagaaa tgggatttca
    10141 aaagaaatcg cagcaaggca ttttttctta gtgttagcac cttacatcac tcggtcgaaa
    10201 agacctgtgg aagaaccgct aaatgtggcg caattgatcg atttatattt gaatggtgta
    10261 ttaggagaag cgtaaagctg ttatataggg agaaaatagt taggtgaaga agcaagatat
    10321 gacgaagatc gttatatctt gcttctttat ataggtagtt tttcataaat acaaatttgt
    10381 tattctctca tgattatcag ggtatatttt tatttattat gtcggtgttc caggaagtgt
    10441 tttaatttaa taacgaagaa attaattgtt tgtagaatga aggaaactat ttattgggta
    10501 gatgaatcac cacgaatagt caaaaggaga tttcaggata tgccaaaaat gaaaaaaatc
    10561 attttagcag taatgttatt ttctacggtt atatctttta cagccccttt tttgcttact
    10621 taagctgatt ttaagttttg gcccttagtc tggatctacg aggtgagagt caagaatgaa
    10681 aaaaataatt ggagcttttg tatttgcaat cattatcatt attatctgtt ttcaaataga
    10741 tgtttttggt caaaaaaaga tagttggaca aacggtcagc agtacgaaca gtacggttac
    10801 aaagacaaag gaatcatttg atgatacaga acaagagaca ttaatcaaaa tcggaaaaaa
    10861 tgaccgtaca ctatatacag atgactcgct aactacccca cttgcaacta taaacggcgg
    10921 agagctggcg gagtttcttt ctgaaacaaa aaatgcttat cagatcaaga caaatgatgg
    10981 ctatactgga tatttagccc tcgaagatgg aaccaaagtc acaaagaata tacaaacaaa
    11041 accggaagag ctatctgatg cagtgattgt attagatcct gggcatggcg gaaatgatac
    11101 tggggcatta agcaatgatg aacaaacaga agaaaaagat ataacattaa gtacagccat
    11161 aaaagtaaaa aaggcgctag aggatgctgg agcaacggtt tatttgaccc atactacaga
    11221 tgaattagta cagcttggag atatatgcga ctacagtgaa gaaaaaaagg cagatgtctt
    11281 tatcagttta cacgcagact ctacggaata tgcgaatgaa gcaactggaa tcacgacata
    11341 ttattactat ggacaagagg aaacattagc acagacaatt gctgactcct tcactgatct
    11401 gcctctggat tcaagaggaa tctccactgg gaactatcaa gttcttcgag aaaatcttca
    11461 accttctatt ttaatcgaga tgggttatat gaataatgat agtgatttaa aggaattagt
    11521 aacagacagt tatcagcagc agattgctgc aagtttgaca caagcattga ccacttattt
    11581 tcagtaataa ataagcccag ccaaacaaaa atagctcctc atatttttcg tttggccggg
    11641 cttattatcg cagatgcaag cttttaaaca ccgtttaagg aagaggtcgt gagcctgccg
    11701 ttcaactctg agtcacaagg agcaatttca aaaaacagct tctcatgttt gatgactatt
    11761 gtgacttgtg accgaggagt tggcatgaga acaccgttta agaaaaaggt tgtgaaatca
    11821 acgttttgtt ctgagtatta gagaaacaaa cggaaaaata gttcctcata ttttgccgtt
    11881 tgttgagcta ataccgagga tcagatgatt gaacaccgtt tattcggaac aagggactgt
    11941 gacatgactt ttgtcacagt tccattattt ttttagtagc ttcaaagctt tttctgtatt
    12001 ggcaaaatga agtttggcat atttttcaag cataggcatg ccgcctttct ccaatagttt
    12061 tgccgctact tggtcagatt tcgttccagc tcctgacgga agggtgattc cagcttcagc
    12121 tgatgctttg tctaactctt ccaaaaagct ggcacgactg atgatagaag cagcagcaac
    12181 agctaaatga tattgttctc ctttagtaac gaagtacagt ttttcttgta attgattttt
    12241 ttctaaacgc gcatattttt taaaatttgc ttccggcgta aactgatcga tcaaaatcgc
    12301 ttctggtttt tctggctcga ttttttttag cagcaaatgg atcgcttgat tgtgcaaagc
    12361 gactttcatc cgaacggcat tgtattttgg ttggatctca ttgtattttt ctggagataa
    12421 gacaagcagt ttatagggga tggttttttt taagatgtca gcaagctgga tgatttggct
    12481 atcttttaac tcttttgaat ctctaacacc aagtttacgt aattctgcaa gctgatcacg
    12541 tttcacataa gcagcacata ctgttagcgg accgaaatag ctgccatttc cgacctcatc
    12601 actacctaaa acggataatt gactgatatt ttttggcaaa gaagaggctg tttttgctgg
    12661 cttggcttgt ttatcctgtg cctcccccca tttatcagct tctattgctg cattcgtacc
    12721 ttgaaacatc acttttccgg atgtataagc ggtaatggtc gtcccgtctt tttttgcagc
    12781 aaagctagta taaggaatct gtttatttaa caaataagag cgatagtatg ctttcatttg
    12841 actaagttgg tcgtttgttg ctttgataat gacgttgctc ataaaattct cctcgttttt
    12901 atacataaaa ctataccgca actcacgact tttcgttttc taagagattg cgagacatag
    12961 cattttttta aagtttatca tataatagtt aagtatgtga aaaatatttg tggagaacgg
    13021 tgaaagaacc aacttcatgg tacactaaat aaaactttca tcaaatagga ggaaatgatt
    13081 cgtatggcgc acgaaaaaac acgctacaaa gcggtgattg ccaaccaaac atatactatt
    13141 atcggacggg aaaccaagca tcatatggat atcgtaacga agctgatcaa tgaacagtta
    13201 gcagaattga aacaattatc accacaaatg gataatgaac aagcagcaat cttgatggct
    13261 gtcaatgcgc tttcggatca attgaagaaa caagaaagaa tattggagct ggaagaagaa
    13321 acagcagaat taaagaaaaa aatgatcaaa tttacagagc ttgaaaatcg tgtgaaacgc
    13381 attgaagcaa tcgagaacga agctcgggaa gtattgaaag aaaatggtca agcagatcat
    13441 accattaaaa atcatgtgga agcacaacag attttaaacg agaaacgaaa aggacaaatt
    13501 aaacaaaaat cttctaatta agatcctttt atcaaaataa gaaaaattta aaaaagttag
    13561 aagagaaagg aacgtagcat gctgagtttg ctgattttat ttttattgct aattgcgttt
    13621 ttttctggag cacgtcgcgg gtttgctttg caaatcatat tcgcgattgg atatgtattg
    13681 tcatttattg ctgcccagca tttttacaaa ccattagcaa gtcatttgga attatacatt
    13741 ccatacccag ctgtcacccc aacatcaaag ttagcatttt ttgatcaggt atttgccttt
    13801 cacctagatg aagcttttta tgcaggaact gcttttctga ttattttgct aattggctgg
    13861 ctgcttaccc gatttgtggg ggtttttgtc catggattga cgtatgtgcc gatcttgaga
    13921 caggtagact ggattgcagg aggcatcctg tcactaatca tggcttacgt tactatattt
    13981 ttgattttgc agttacttgc ctttgttcca ttagatgtgg tccaaaatca attcggcgag
    14041 catagtttcg ctcgttttat cgttgagaga acgccatttc ttaccaacaa gatgtatgag
    14101 ctttgggtaa cgaatatttt gaattaagga aaatagtgct ggaaaatatt tcgttttttg
    14161 tacagagtag tttatttaag aaggctgcgt agcgtatgtc cggcacagct cttttttcat
    14221 agtgaaagat aaggtgataa aatgaataac cgaatccttg aaacattgga atttgaaaaa
    14281 gtcaaacaga tggtcagaca atttgtagtg actgcacaag gaaaagaaga actggcagaa
    14341 ttggtaccag tgagtgagaa acaaacgatc acaaactggc ttcaagaaac tgaggatgga
    14401 ttgaaagtgc aacgtctgcg aggcgggatc cctataccta aaattgaaaa tatccgtccc
    14461 catatgaaac ggattgagat cggagcagac ttgaatggag tggagcttgc acaagtttcc
    14521 agagtattgt ctacgacaag cgaattgaat cgtttcattg atgatctttc tgacagtgaa
    14581 atcgaatttg cacgtttgta tatgtgggca gatcagttag tcacgatccc tgttttgagc
    14641 cgccgtttaa aggaagcaat cgatgaagac ggacgcgtga ctgatgacgc ttctcctgag
    14701 ttaaagagca taagacagaa cattcggcga agtgaacaag ctgttcgtga acagttagat
    14761 gggatcgtcc gtgggaaaaa tgcaaagtat ttaagtgatg cgatcatcac catgcgaaat
    14821 gaccgctacg ttatcccagt caaacaagaa taccgcggtg tatttggcgg tgtagtccac
    14881 gatcaaagtg cttcaggtca gactttattt attgaaccaa aacaagtggt ggatttgaat
    14941 aatcgtttgc gtcaatacca aatcgctgaa cgaaatgaga ttcaacgtat tttaagtgaa
    15001 ctttctgctg aacttgttcc ccatcgtcaa gaaatcatcc acaatactta tgtgattggt
    15061 aaaatggatc tgatgaatgc aaaagcacga tttggtaaag aagtaaaagc catcgtgccg
    15121 ggaatcagtg aagacaatca tgtcgtcttg aaacaagcaa gacatccact gatcgatcag
    15181 gaaaaagtag tttctaatga catcacaatc ggaaaagact atcaagccat cgtcattaca
    15241 ggacctaaca caggtgggaa aacgatcacg ttgaagactt taggtctgtt acaactgatg
    15301 gggcaagcag gattaccgat tcctgcaggt gaagaaagtc aaatcggtat ttttgaggaa
    15361 gtatttgcgg atataggaga cgaacagtcg attgagcaaa gtctatcgac cttttcttct
    15421 catatgacga acactgtaga tattttatca aaagtcaatg aaaaaagtct ggtattattt
    15481 gacgagctcg gtgcaggaac agatccgcaa gaaggtgctg ctctagcaat cgcaatctta
    15541 gatgatcttg gtaaaaagtc tgcttatgtg atggcaacaa cgcattatcc tgaattgaaa
    15601 gtttatggat ataatcgggc aaatacgatt aatgccagca tggagtttga tgtggataca
    15661 ttaagtccaa cgtatcgttt gctgattggc gttcctggac gaagcaatgc gtttgaaatc
    15721 tctagccgat taggtcttga tacagaagtt attgatgaag cgaagcagtt gatgaatgat
    15781 gagagccaag atttaaacga aatgatcaca gatttagaga atcgccggaa aatggcagag
    15841 accgaatatc tggaaatgcg tcattttgtt tctgaggcac aagaacttca cgatgatttg
    15901 aaagaagctt acagctattt ctttgaagaa cgtgaaaaag aaatggaaaa agcaaagaaa
    15961 aaagcaaatg aagtcgtgtc agaggcggaa gaaaaagcag aaaaaatcat tgctgatatt
    16021 cgtaaaatgc aacagcagat tgggcaagga aatgtgaaag agcatcagtt gatcgatgca
    16081 aagacccaat tagcaaatct acatcaagaa gaaactttga agaaaaataa agtattgaag
    16141 aaggcgaaag aacaaaaaac gttgaaaccg ggagacgaag tgttggttac gacttacggc
    16201 caaagaggga cgcttttacg taaaaacggg aatcagtggc aagtagaaat cggtatatta
    16261 aaaatgaatg tgtccgaaga cgagctgacg cctgttgctc ctcaaaaaga gccgacacaa
    16321 cgagttatcc atgctgtacg atctgaatct agtagtcacg tgccgaatca attggacctt
    16381 cgaggaaaac gatacgaaga agcgctaagt gaggtagatc aatatttgga ttctgccatt
    16441 ctagctggtt atcctcaagt gactattgtc cacggaaaag gaacaggcgc acttcgcaag
    16501 ggaattactg attatcttaa aaaccatcgg agcgtcaaaa gctttgagtt tgcaccggca
    16561 aaccaaggcg gaaatggtgc gacaattgtt aaatttaagt aaagcttact aaaggtaagc
    16621 agatggttcg ctatccaagt atagaaatgc tatactagtc atagatttta aaaatggagg
    16681 tctttgatat gtcacaagta attacagata agacatttaa tgaagaaaca gataaaggac
    16741 ttgtattgat tgatttttgg gcaacttggt gtggtccatg tcgtatgcaa gcaccgattt
    16801 tggatcagtt ggaacaagaa tatgatgaag aagaattcag aattgctaaa atggatgtgg
    16861 atgaaaatcc agaaactcct caacaattcg gtatcatgag cattccaaca ttaatgttga
    16921 aaaaagatgg tcaagtagta gaaaaagctg ttggtgttca ttcaaaagaa caactacgtc
    16981 aaatgatcga tcaatattta taaaaactta cagcaaaaat aagctgaggg tgggactgaa
    17041 tccagttccg tcctcggttt ttttgcggtt gagttaaggt tattcaaatt aatatttttt
    17101 gagtataatt acgttgtcag gctggattgt ttttttgaca gacatgctat aataacttta
    17161 attgaatatg aaggggagta ccagatgaac gaacgaatca aaaacaaatt agctttactt
    17221 cctgatcagc ccggctgtta cttgatgaaa gataaaaatg gaacgatcat ttatgtcggc
    17281 aaagccaaaa tattaaaaaa tcgtgtccgc tcatatttta ctggtagcca taatacgaaa
    17341 acggaacggc ttgttagtga aatcgaagac tttgaataca tcgttacaga atcgaatatc
    17401 gaagcattgc tcttagagat caatctgata aagaaaaatg atcctaaata caacattatg
    17461 ttaaaggatg ataaaaccta tcctttcctt aagataacga atgaaaaata tccccgtttg
    17521 gtgattactc gtaaggtact aaaagacaaa gcactgtatt ttggaccata tcccgatgtc
    17581 ggtgcggcga atgagacaaa gaagatcctc gatcgattat ttcctctgag aaaatgcaaa
    17641 cctagtcaga cgaaggagcc ttgtctttac tatcatttgg gacaatgcct gtgtccttat
    17701 tatttcgacg tagatccgaa agtctatacg aaaatcgttg atgaagtgaa aaacttttta
    17761 aacggaggac acgaaaaaat cgagtcagag atccatcaga aaatggaaaa agctgctgaa
    17821 aacatggagt ttgaaaaagc tgcagaatac cgagaccaga tccgtgccat tgagacaatc
    17881 atgactcgcc aaaaaatgac aaatactgat ttactggatc gagatgtatt tggttatgcg
    17941 attgataaag gatggatgtg tgtccaagtg tttttcgtaa gacaaggaaa gctaattgaa
    18001 cgagatgttt caatgtttcc tttctataac gaagcagaag aagatttctt gacttacctc
    18061 ggtcagtttt atcaggaaaa tgagcatttc attcctaaag aagtcttgat tcctgatacg
    18121 atcgacaagc ccagtgtaga agctttgtta gctacgaaag tgctgcaacc aaaacgagga
    18181 gaaaagaaaa aattagttga attggcgagt aagaatgcct cagttgcttt gaatgaacgg
    18241 tttgatctga ttgccagaaa acaggaacgg acgatcggag cagttgaacg tttaggaaac
    18301 gcgatgaata tcccgacccc aatacgtatc gagtcttttg ataactctaa tatcatgggg
    18361 acgaatcctg tggctgcgat ggtcgtattc attgatggaa aaccggcaag aaaagaatat
    18421 cggaaatata aaataaaaac agtcaacgga ccggatgatt atgcatcaat gagagaagtc
    18481 atctatcgca gatattcgcg agtgattcgc gaagggttgc ctttacctga tttgatcttg
    18541 atcgatggag gaaaaggaca agtagatgtg gcaaaagatg tcttagaaaa tcaattagga
    18601 atcgatattc ctattgctgg catggtaaaa aacgataaac ataaaacaaa tgagttgcta
    18661 ttcggtacag atttggctgt agtaccgctt gagcgaaatt caccagagtt tttcttactc
    18721 cagcgaatcc aagatgaagt ccatcgattc gcaatcactt tccatcggca gctacgcagt
    18781 aaaaacagtt ttgcttcccg attagatgaa attgaagggt taggaccaaa acgaaaaaaa
    18841 atgctgctta aagagttcaa atcgttgaaa aatatcacag cagccacgac agaagaatta
    18901 caagaaatcg gactgccgaa aaatgtcgca caaaacgtat ttgataaatt acatcaggaa
    18961 tgaggaaagg gcactttaca aagaaagtaa agtgtcctat cattttatgt acaacaaaaa
    19021 gagcgtttac gttttgttgg taaataataa atcgcttacg tctggtgtct aaggatatat
    19081 gtgatttctt gaagaaggag tgaagaaatg ttagaagtca aggatcttgt taaaactttt
    19141 gggaactaca cagctgtcga tcatgtctct ttccaaatcc ccgatggaaa aatcatgggg
    19201 ctaattggcc aaaacggggc tgggaagaca acgacttttc gtttgatctt ggattttttg
    19261 acacaagacc aaggagaagt gttatggaat ggccatcatc ttggggagaa agattatgat
    19321 gtcatcggtt atcttccgga ggaacgggga ctttatccga aagtaacgat tcaagaccaa
    19381 ctgctttatt ttgcagaact tagagggaaa tcaagaaaag agattgaacc aaaaatcgac
    19441 ttttggatgg aaaaatttca ggtaaaaggg aaaaagacgg ataaagtaaa atctttgtct
    19501 aaaggaaatc agcaaaaagt ccagctgatc gccacgttaa tccatgaacc taaattgatc
    19561 attttggatg agccattcag cgggttagat ccggtaaatg ctgaattgct aaaagatgga
    19621 atattggaat tgaaaaaaca tggttcatgt gtcatttttt ctagccacaa tatggataat
    19681 gtagaaaaaa tctgcgatca tttgatcatg ttgcgaaacg gaaaaatggt tttgaatgga
    19741 aaagtacatg agattcgtga atcatttggc cgtacgaagt tattcttgga atctggttta
    19801 agccaacagg aagtagaaga aatcgaaggc gtgaaaaaag tgatccttca tgaagacaat
    19861 acgttagaga ttaccttaga agatcctgaa gctgggaaag aaatctttac tcgtgcgact
    19921 cagttcggct acattcctat gtttaaccag caaccgccaa ctttggaaga gattttcaaa
    19981 ttgaaagcag gtgaaatcga tgcgtaagtt ttggattatt accaaagatg tctatttaaa
    20041 aaatgttaag tcgatttctt tcttgatcat gatattagtc ccttttatca tgctgggtat
    20101 catttatgta gcaggaaact ttgctcaaca aaatagtgat gtcaataaaa tcggcgtatt
    20161 ggctgataat gagcaaatca gtcagcaaat gagccaagtc aaaacagatg attttgagtt
    20221 caaagcagtt gattctgaag aaaaagcaca aaaagagctt tcggaagaaa aaatcgatgc
    20281 gtatttagta gtctcaactg agaatgataa gataaatggg atgctttata gcgaaaattc
    20341 attaggacaa agtacacaac tactgataca acaacaactg actggcttgc aatcgatgct
    20401 tcgagcgagt caattaggca tttcaccaga agaagtagct agcttgagcc aacaagcaag
    20461 tttgactcga caaaaagtca attttgattc aaaaggaaaa atgacagtcg gagaagataa
    20521 ctcgacagtc caatacgtcg taagttatgt agcaacgatt gtcttgttca ttattatttt
    20581 gacgtatgcg cagatcattg cacaagagat cgcttctgaa aaaggcacgc ggatcatgga
    20641 agtgatcctg tccagtacga ctgcacaaaa gcatttttac ggaaaattaa caggtgtttt
    20701 acttgttgca ttaacgcaaa tggcattata cggtattatt tttggtatag gatacagtca
    20761 attcaaagat atggaaatgg tcaaaaatat attagacggt atctcattgg ataacttgat
    20821 tggaccattc ttgtggtatt ctcttctatt catgatcttt ggcattttga ttttttctgt
    20881 tttagcagct ttatgtggct ctttggtcaa caaagcagaa gatacagcaa aagcaatttt
    20941 gccagtgact tatctatctc taggcggata catgcttgga ttgatactag gagcttcaga
    21001 tccaaacaat atcgttattc ggatcacttc gtatattcca ttcttatctt catatattat
    21061 gccgattcgc ttagcaaatg agacagtcgg tatgggtgga gcattgattt ccttgttggt
    21121 acttgtagcc gtaacattct tattgatgat cttgtctgca aacatgtaca aatcgaatgt
    21181 actcgtttat agcgaaggcg gattatggag ttcattgaaa caatcgattt caattatgag
    21241 gaatgaacga aaaaaagcat aaaacaatcc taaaatacag aaggaagctg gacatctatt
    21301 gttcccagct tctttttgta tagacctatt ttatttattt tactatattg gatatatatt
    21361 cattgaaaat agtgtataac aactttataa tattgagtat accaattttt ggaggcgttt
    21421 taatggaccg ttatttagat ttactttcag aaaaattccc ctcaacggag gatgtcatca
    21481 cggaaatcat caatctcgaa gcaattttgc agcttccaaa aggaacagag ttatttttga
    21541 gtgatataca tggcgaattt cctgcttttg atcatattct gcgtatcggt tcaggaaatc
    21601 ttaaagaaaa gatcaaagac cttttttctg aacaaatgac ggaaacggat atcagccaat
    21661 tcactatttt tacggcttat ccagaatatg cattaacgac tgattggtac aaagaacaag
    21721 ataaatcgca gctgatccat catttgatcg atcttttacg gtttacgaca gtcaaatata
    21781 cccggtcaaa agttcgaaaa ggattgccga aagaatatag ctatatcatt gaggaactct
    21841 tgtatatcga tgaccgtatc aatggaaaaa aagactatgt aaaaaaaatc attgaacaac
    21901 ttgttttgat gaaggaagaa gaaaaatttt taacgaaact tgcacagacg atccaaaaat
    21961 ctgtcatcga tcatttgcat atcgttggag atatttttga ccgaggaact caagcagcca
    22021 aagtgatgga tcgaatcatg gatttttctt ctgtagatat ccaatgggga aatcatgata
    22081 ttttgtggat tggtgcgtat tgcggctctg aggcatgttt actgacactt ttacggattg
    22141 cagcacgcta taattattta tttgaattag agaaagaata tgggttgaat ttacgtccat
    22201 tgttttcttt tgctcatcaa acttatcaga agaatccagt atttgcgcct aaaaacagta
    22261 aaaatctatc cgaaagagag caagaagaat tagaaaaaat ccatcaggca ctttctatcc
    22321 ttcaattcaa atcagaacat cagttattgg atcgtcgacc tgaatttaaa atggacgatc
    22381 gtaaattgct ggaaaaaatc gactatgaag catcaacgat tgatttagaa ggtcagctct
    22441 atgagttgaa aggaacttgt tttcaaacga tccagccaga tgatccaaaa aaattcttgg
    22501 aagaggaaca aaaagtgatt gatagtttga tgtattcatt ccagcactct ttgagaatgc
    22561 aaaaacatat gacgtttttg atcgaaaaag ggggaatgta tctcacgaac aatcagcatg
    22621 tgctgtttca tggctgtata cctgtagacg agaagggaca gctcttagca tttgaattag
    22681 accaatctta tcgcggaaaa gaactgctgg gcttttttga aaaacagata actgaaagcg
    22741 caaaagatct gactgcaaaa gaagatttag caaccgattt gatttggtat gcgtggagtg
    22801 ggccattttc gcctttattc ggcaagagta aaatggcgac ttttgaacgt tattttctca
    22861 cagagcctca tacgcacgtc gagaaaagca atccttatta tcacttgcga gatgaagagt
    22921 ggttcagtga aaaaatttta gcagaattcg acacaaaaga agaagggtca gcaatcatta
    22981 atgggcacac gccagtaaaa gtaaaaaaag gggagtcacc gatcaaagca aatggaaaag
    23041 tatttgtcat tgacggaggt ttatccaaag cttatcaaaa aacgacagga attgccggtt
    23101 attcactatt atgcaattct tatggtttcc aaatcgtgac acattatccg tttttgccta
    23161 ttgaacaaca atttgcaaaa aaatccgacc aaacaaatgt gaaaaaagta atcgaacagc
    23221 aactaccacg caaactcaat cgtgatacaa caaaaggtat ggaactgcag cagcagatta
    23281 cccagctcaa aaggctgttg gactatcgaa aggacgattg agaagaattc cagtgaacat
    23341 tgttccatag actggagact gagacaaaag tcgtgtcgca gtctcttttt ccggataaac
    23401 ggtgttcttc tgccaactcc tcggtcacaa gtcacactat tcaacaaaca tgaaaagctg
    23461 ttttttgaaa ttgctccttg tgactcagag ttgaacggca ggctcacgac ctcttggtat
    23521 aaacggtgtt caaaagccag tttctcggta ttaagccaaa tttatgcaaa aatgtgaaaa
    23581 gccattttca caaaattttt cttaatactc gaaactaaac agctttttca caaccccctc
    23641 agaaagtcta ttaaaattca ttcacaaaga aatcgaataa gcgctgttca gatggatgta
    23701 cacggtgggt aagttccgga tgccattgaa caccgaggat tttatgcata tcatctttgc
    23761 tttgaaccgc ttcaacgagt ccatcgttag aaaaagcgat ggcttttaat aaaggtgaaa
    23821 gatctttgac tgcctgatga tggtaagaat tcacaaaata tggatcgggg agaaggttgc
    23881 ttaacaaact gtctgaaaca atcttgactt cgtgagtcgt aaattgcggg gcagtgggct
    23941 gttgttcatg ttttactgac cactttggat ataatgaaag atcttgataa agtgtacctt
    24001 ccaaaacgac attcaatagt tggagtcccc ggcagactgc aaaaattggt tttctttgtt
    24061 tcaatgcttc caagatcagt gcctgttcaa attggtctcg ttgaatattt gtttccgtta
    24121 gctttggatg aggatcttcc atgtaaagtt gtggactgac atcttgacca cctgcaagaa
    24181 taagtttgtc gatttgtcca atcagttgag gagctgaatc tggagacatg actggcagaa
    24241 taagaggcaa tccttgagca tctaaaactg catccacgaa tccttgcggt gtatagctca
    24301 cttgatttcc ttggaaagta tctgttgctc gaatcagttg atttccggca atgccgatga
    24361 ttggtttcat ttgtattccc cctaaagtag acttattgta acaaggattt aaaaaaaatt
    24421 aaactatgta agacttgccc ctatacttat ctgttcttgc tgtgttacta tctgtaaaga
    24481 gaaatttcgt gtgaaattca tgacgatagt tgaaaatatt gcttaatttg ttataataaa
    24541 aagtaagcag aaataaaaag gttgggcgta agcttcaagg atctagttct tcaaggggtg
    24601 agaaggacat tttattgaag gggcctgcct atactaagtt atctttagag gtacatactt
    24661 tcaatgaaaa aagaaagcat gtacctcttt tttaaatcga aaggaagtga agcaagtgtt
    24721 agaagctttg gaacaaatcc gaaaagcaga agaagaaaat gaaaagcgtg ctcaaacact
    24781 gcggcagcag ctgaagatct atgcaacaga aaaagagcag gaattggaaa cgatccaaac
    24841 aaactatcga caacaactaa aacagttggt ggaagaaaaa gaacaatttg aaatacaaga
    24901 attagaaaaa gaaaaaatga aattgaaagc agaagcagac aaggtgcaag caactttgaa
    24961 agatcaatat caaaagcatc agagtcaagc gatcggtgcg atcattgaaa gggtgaaaga
    25021 aacttatggc cgtcactaag atggaaaaag tgaccctcat ttcagataaa agaaatcagg
    25081 agaggatttt acaagcagta caaggaatcc aaaacgttga aatccgggat ctgtatcaaa
    25141 atagaacaaa caaccagtgg gtggagaagt attttccaga taccacgatt attgataaag
    25201 aagcaaaatt aagcgcttta ggtaatcggt tgaaagacat ccaagaagct atccaattca
    25261 tacaacacca cggcgatagc cgtcaaaaga aactccattt gaaacgtcaa gaactttcct
    25321 tacaagattt ggaagccaat tattccgaag aaaatttcat aaataaattg aaagaagtcc
    25381 ttgatttaaa agaaaagtgg gaacaactaa ctgaagaacg tgatcgttta gaagaagagg
    25441 aagaatggct tcttcattgg caacagctgg atattgctcc aagtatgtat gcaagtaaga
    25501 cgaccatttt tgagatgggg actgtgagtg cagcaaattt tgaaagtttc aaggaagaac
    25561 tgagtaagct tgatgacgtt tatatggaag aaatagatta tacgccaaaa caagtttatc
    25621 tttcgtatgt tgctttaaaa aaatcagttg ctgttataga agaaattgct gggaaatacg
    25681 ggttcaataa agaaacgtat ccttatgaac aaaatcctaa agaaaaactg caagagacca
    25741 agcagcaatt atccattgtt cacgagcagc aaaagaagat aacgacagcg ttaggtcagt
    25801 gcagtggcta tatccaagaa tttgaatggg tagaagaagt cacacttgcc gttgcagaac
    25861 gagaaaaaat aaaagaacgg tttatccatg cgacttatct gatcgttttg caaggttggg
    25921 tagatgcaga agaaaaacag aatttgctgc atgtgttaaa cgaaaccgta tcagaagaag
    25981 atatatacgt cagtttcgaa acaccaaact cagaagagat tcagcaggaa gtccctacta
    26041 aattgaaaaa ccatccgctt gtcgaacctt ttgaattgct gactgaaatg tacagtctgc
    26101 caaaatatga agaagtagat ccaacacctt ggatgacacc attttatctt gtcttcttcg
    26161 ggatgatggt cgcagatgtt ggttatggtt tgctgatgct cattgggaca atactagctc
    26221 aaaaactact tgttctacca cgcgggatga aacgtttcgt aaaattcttt gagattctct
    26281 cgataccatc gatcatctgg ggattgatct acagttcatt tttcggacag tcattaccaa
    26341 aagaactgtt tggcatccgc ttgcctttcc caatcctatc tacgacggat gacgtcaata
    26401 cgattttgat tttatccgtg attttcggtc tgatacagat tttggttgga ttatttgtgg
    26461 cagcaaagga aaatatcagg agaaaagatt acttgagtgc tgtcagtgat ggatttgcct
    26521 ggcaagggat cctaattggg atcgttattg cgttggttgg tgccatgttg ataaaaaata
    26581 cagcatttgt ttaccttggc gctgggctat cgatcattgc tgccttatgt atcttgatcg
    26641 ttccgattat ccaaacgccg tctaaagtca aaggtgctgc caaaggtgcg tataatcttt
    26701 acggactgac cggctatatc ggtgatttag tcagttatac acgtttgatg gcattgggta
    26761 tttcaggcgg aagtattgga gcggcattca atatgctagt tgctttcatg ccgccagctg
    26821 ctcgattcag tgtagggatc cttttgatca tcgctttaca cgcactgaat atgtttttga
    26881 cactgctaag tgcctatgtc catggcgcac gattgcagta tgtcgaattt tttgggaagt
    26941 tttatacagg aggcggacgt gcctttgatc cgctgaaaac ggcggaaaaa tacgtcaaca
    27001 tcaatcacaa gaaaaaaaac aataaataat tggaggattt ttatataatg atggattact
    27061 taattagtca aaatggtgga atggtatttg cggtattagc gatggcaaca gcgacgattt
    27121 tttcagggat cggttcagct aaaggtgttg gaatgacagg tgaggcagca gcagcattga
    27181 caacaagtca acccgaaaaa ttcgggcagg ctctgattct gcaattgctt ccaggcacgc
    27241 aaggtttgta tggattcgtt attgcctttt tgatttttat caacttagga aatgacatgt
    27301 cagttgtaca aggactgaac tttctaggtg cttctctgcc gattgctttt acaggcttgt
    27361 tttcaggtat tgcccaagga aaagtcgcag cggcaggtat tcaaatttta gcgaaaaaac
    27421 ctgaacatgc tacaaaagga atcatttttg ctgcgatggt tgaaacatac gcgattttag
    27481 gtttcgttat ttccttccta ttagtgttga atgcctaagc ataaaggagg aaaagcagat
    27541 gaacgccatt gaaaaaatca tctctcagat gaacgaagca gcagagcagg aaagagcggc
    27601 gttagaacaa gaagagcgaa tgaagatcga tcaaaacttt gaacaaaaac gtacgcaagt
    27661 tgaaacagaa catcaaaaac aaaaagaaaa acaaatcgaa ttactcgaaa aaaaataccg
    27721 tcagctaagg aatcgccagc aagtagaagt acgacaagaa aatttgaatg cgaagcagga
    27781 atttttaaga cgattgtttg cagatgcggt aactgaaatg gaaaattggg atgaatctga
    27841 acaaatccag tttatcaaaa atgcattgta ttcattacct ttgacaggaa aagtagcatt
    27901 cattgctgga gaaaaatcag cagcctatct ttctcagacg ttgttggatg aatggaacaa
    27961 tgaacttccc tttatgatgg ttttaagtga tgaaactgtt gctgatcaag cgggttttct
    28021 gataaacgat caaggagttc agtataattt tcttttcagc agccttgtac aagatatcca
    28081 aggaacgatg agttttgaga ttgccaatca attattcgaa taaggaggga tcagtgtatg
    28141 gaataccacg aactaaatcc cttgattcgc ggaagagagc ttgaactttt gtccaatgag
    28201 acatttgaac ggatgattca aacaaattct gtcgaagcac ttggtgaaat attgaaatcc
    28261 acgatttaca gtccatatat ttatgacgga tatgaatatg acttcgaaca gaatctttta
    28321 aaggagcaga gccgtctatt tcgctggtta aaggaatcag caccggagcc tgaaatcgtt
    28381 tggatctata cgatgcgtta tactttccat aatctgaagg ttttgacaaa agctgagatg
    28441 acaaatcaaa atctggacca tttgtatatc gacgatggat tttattcatt agaaaccttg
    28501 aaggatgcca ttcatacgca agtttcaaat gaacttcctg aaagcattat ggacagtata
    28561 cgagaagtac gtgattattt tgaagagtct accattcttc agggaattga cgtgatttat
    28621 gatcgacagt ttttgacaga gcagcgacgg cttgccgata agctaggata tcaagaattg
    28681 ctgacagaag tcattgcttt tattgacttg accaatatca caacgatggc tcgaggaata
    28741 ttgcagaaaa gaacatatgg gttcatgacg acggtacttt ccagctcggg aagtatcgaa
    28801 aaagaagtat ttttgaactt tgtagataaa gatatggaag attacacgaa ttttctatta
    28861 gagacagatt atgctgattt tctgcgccct gtcatccgtg agggaaatat tgatctcgta
    28921 aagcttgaac agttgaaaga tgattatcta agttcattgt atcaagaagc acaaacccag
    28981 gctttcggac cactgccact actagccttt ttgaacgcaa aagaggtaga aagcaaaaac
    29041 cttcgtttac tggttatcgg caaaagaagc catttcgaat cagaaacaat cagaaagcgg
    29101 gtgagacaag tctatgacgc ataagatcgg tgtagttggc gacaaagatt ctgttttgcc
    29161 attcaaattg tttggctttg atgttcgtta tggtacaacc aagcaaaccg ttcgtcaggc
    29221 aattgaagaa atggcaaaga atgagtatgg cgtgatttat gtcacagagc aatgtgcagc
    29281 attgagccca gaaacgatcg aacgttacaa ggaacaaatg atacctgcta tcgtattgat
    29341 tcccaatcat caaggatcat tagggatagg gctggaagaa attcaaaaaa acgtagaaaa
    29401 agcagtaggt caaaatatct tatagtatga aaaggagata gaaattttgc aaattggaaa
    29461 aatcataaaa gtctccggac ctcttgtaat ggctgagaac atgtctgatg ccagtatcca
    29521 agacatgtgt ctagtgggag atctaggagt tatcggagaa attatcgaga tgcgtggcga
    29581 tgtggcgtct attcaagtat atgaagagac ttctggaatt ggtccaggcg aaccggttcg
    29641 ctctactggt gaagctttat ctgttgaatt aggaccaggg atcatttcac aaatgtttga
    29701 cggaatccaa cggccattag atacctttat ggaaatcaca caaagtaatt tcttagggcg
    29761 cggagttcaa ttgcccgcat tggaccatga gaaaaaatgg tggttcgaac caacagtaga
    29821 agccggagaa acggtgagtg ctggagatgt tatcgggatc gtagaagaaa caaaagttat
    29881 aaaacataaa atcatggtgc caaatgggat aaaaggaacg atcaaaacaa tcgaaaaagg
    29941 ttcattcact attgatgaaa cagtatgtgt cattgaaacc gaaaatggtg acaaaaattt
    30001 gacgatgctt caaaaatggc cagtaagacg tagtcggcca atcaaagaaa aattaaaccc
    30061 ggatgcaccc atgatcactg gacagcgagt gattgataca ttcttcccag tgacaaaagg
    30121 aggagcagca gctgtacctg gtccttttgg tgcagggaaa acagtcgttc agcatcaaat
    30181 tgcaaaatgg gccgatgtgg acatggttgt ctatgtggga tgtggcgagc gtggaaatga
    30241 gatgacggat gttttaaatg aattccctga attgattgac cctaatacag gagaatcgtt
    30301 gatggaacgt acggtattga ttgctaatac atcaaacatg ccagtagcag ctcgagaagc
    30361 ttctatctat acgggaatca caattgcgga atatttccgt gacatgggtt atgacgttgc
    30421 tatcatggca gactccactt cacgatgggc agaagcactt cgtgagatga gcggacgttt
    30481 ggaagaaatg cctggtgatg aaggttatcc agcttatctt ggttcacggc ttgcggaata
    30541 ctatgaacga tctggaagag tcattgcatt aggatcagaa ggtcgcgaag gaagtataac
    30601 cgcaatcagt gctgtatccc cgtctggagg ggatatttcg gaaccagtca cacaaaatac
    30661 attgcgggtc gtaaaagtat tctggggtct tgattccagt ttagcccaaa aaagacattt
    30721 tccttcgatc gattggatac aaagctattc tctttattca acagaagtag ggaagtatat
    30781 ggatcatatc cttcaagctg actgggcatc catggtcacc gagggcatgc gtattttgca
    30841 ggaagaacag cagctgaatg aaatcgtgcg tttggtaggg attgattccc tttcagataa
    30901 tgaccgtctg acattagaag tggcaaaatc cattcgtgaa gattatttgc agcaaaatgc
    30961 ttttgatgat gtcgatacat tcacttcaag agagaaacaa ttcaaaatgt tgaagatgat
    31021 cttgaccttt ggtgaagaag gacgccgtgc gttgtcgtta ggtgcttatt taagtgagat
    31081 catggacggt accgtatcga ttcgtgaaag gatcggacga agcaaatata tcccggaaac
    31141 agaattagaa aaactagatc aaattattgg tgaaatcaag caaacgatgc aaacgatcgt
    31201 ttcagaagga ggcatgagca atgattaaag aatatcgtac gatcggtgaa gtcgtcggtc
    31261 cattgatggc ggttgaaaaa gttgctggtg tcaaatatga agaattaatc gaagtccgta
    31321 tgcaaaatgg cgagattcgt cgtggacaag tattggaagt ccaagaagat aaagcaatgg
    31381 tccaaatatt cgaaggaaca agtggtatca atttacgtga ctcttctgta cgatttttag
    31441 gccatccttt agaactaggt gtatcggaag acatgatcgg tcgagtattc gatggtttgg
    31501 gacgaccgaa agataacgga ccagagatcc tgcctgaaaa gcatttggat attaacggag
    31561 aagtaatcaa tccagtagct cgggattatc cagatgagtt tatccaaaca ggtatctctg
    31621 caatcgatca tttgaataca ttagttcgtg ggcaaaaatt accagtattt tctggctctg
    31681 gtcttcctca taaagaatta gctgctcaga tcgcgcgaca agcaacggta ctcgattcat
    31741 cagatgattt cgccgtagtc tttgctgcta ttggaatcac ttttgaagaa gctgaatttt
    31801 tcatggaaga ttttcgtcaa acgggcgcaa tcgaccgttc tgtcatgttt atgaatttag
    31861 caaacgaccc tgcaatcgaa cgtatcgcta ctcctcgtat ggctttgact gctgcagaat
    31921 atcttgctta tgaaaaggga atgcatgttt tggttatcat gacagacatg accaactatg
    31981 cagaggcatt gcgagagatt tctgcagcac ggcgagaagt tccaggaaga agaggatatc
    32041 ctgggtatct ttacacgaac ttagctactt tattcgaacg agcaggaaga atccgcggac
    32101 taaaaggatc ggttactcaa attccgattc taacaatgcc agaagacgat aaaactcatc
    32161 caatccctga cttgactggt tatattacag aaggacagat catcttgact agagagcttt
    32221 acaagagtgg gattcagcca ccaattgatg tactcccgtc tctttcgcgg ttaaaagata
    32281 agggaactgg acccggaaag acaagagaag accatgcagc tacgatgaat cagctttttg
    32341 cagcctatgc acaaggaaaa caggcaaaag aattagccgt agttttaggt gaatctgctt
    32401 tatctgatgt agacaagatc tatgcgaagt ttgctgagcg gtttgaaaaa gaatatgtca
    32461 atcaaggatt ctacacgaac cgttcgatta ctgaaacact tgatctaggg tgggaactgc
    32521 tatcgatgtt gccaagaacc gaattaaaac gaatcaaaga cgacatgctg gacaaatatc
    32581 tgccagaagg gaagtgagtt ctgatggcac gattgaatgt gaatccgacc cgcatggaat
    32641 tgactcgatt gaaaaaacag ttgacaactg ccacaagagg gcataaatta ttaaaagata
    32701 agcaagatga actgatgcgt caattcatcc tgttgattcg aaagaacaac cagctgcgtc
    32761 aagaaatgga agagtctatg acagaagcaa tgtctgattt tgtattggca aatgcttcga
    32821 tcacggaacc tttcatcgaa gaattatttg ttttgccggc ggaaaacgtt gatttgtcta
    32881 tcgtagacaa aaatatcatg agtgtaaaag tacctgtgat gaattttgaa tatgatgaac
    32941 agctgacaga cacacctttg gaatacgggt atttgaattc cagtgccgaa ctggatcggt
    33001 caatcgatcg gtttactacc ctgcttccaa aacttttgga actgacagaa atcgaaaaaa
    33061 cttgtcaact gatggcgagt gaaatcgaaa agacacgtcg gcgagtcaat gcattagaat
    33121 atatgacgat ccctcaatta gaagaaacga tctattatat tcgtatgaag ctggaagaaa
    33181 acgagcgcgc agaagtaaca aggttgatca aagtaaaaaa tatgggtacc actgactaag
    33241 tggtatcttt ttttaaaaga ggaaaacgat gattaaacaa agcaaacaaa taaagaaacg
    33301 tttgccggct gttcagcttc tcgcattagg attttttctc ctgattttag ttggcggcgg
    33361 cctacttacc ctaccatttt ttagtaatag tgggcatggg acaaatttta tcgatgcgct
    33421 tttcactgca acttctgctg tctgtgtaac gggattgaca acattgaata cagcagagca
    33481 ttggaacagt gctggtcaat ttttgatcat gcttttgatt gagatcggcg gtcttggttt
    33541 tatgatggtt ccgattctat gctttgcatt gataaagaag aaagtcagtc tcagcacacg
    33601 tattatatta aaagaagcgc tgaatctaga agaagtatca ggtgtgatga agctcatgct
    33661 ttacatccta aaattggcct ttgtgatcca attgattggt acggttgctt tatcttttgt
    33721 atttgtgcct gaatttggct ggttgaaagg tatctggtac agtttgttcc atgcaatctc
    33781 tagtttttgt aatgcagggt ttgatttgtt aggagacagt ttagccaatc accagcaaaa
    33841 tgtttatttg atcatggtgg tatctgcttt gatcatttct ggtgggttag gcttcatcgt
    33901 atggcgtgat ttactggaat atcatcagaa aaagaagatg acgattcatt caaaaatcgc
    33961 attaaccgtt acaggtaccc ttttattagg cggattcgtt gtgttctttt tcacagagcg
    34021 caatggggca acgctagtgg aagggaatat gtttcaacga ttggcaaaca ccttttttat
    34081 gagtgtgaca cctagaacgg ctggatatta ttcagttgat tacctccata tgagccatgc
    34141 aggtctgatt ttaacgatgt ttttgatgta catcggcgga acatctgggt cgacggccgg
    34201 cggattgaaa acaactacgt taggtgtgtt gctgatccag atgcgttcga tgttgaaagg
    34261 acgtacgaga gcggaagcat ttggccgtac catccgacaa ggcgcagtgt tgcgggcact
    34321 tactttattt tttgttacgt tgacgttgtg tgtagtcgcc atcatgattt tatcggtgac
    34381 tgaaacgata cctaaaactt ctggcatcga atatattgct tttgaggtct tctctgcgtt
    34441 tggtacagta ggtcttacga tgggattgac gccagacttg actgcaatag ggaaattgat
    34501 cattatagcg cttatgtaca ttggacgagt tggtgtattg actgtggtct tctctctgat
    34561 gacaaaagca caaagaacac aatcaaaata caaatatcca gaagaaagtg tcatgattgg
    34621 ataatttcat cttctgacag aaacctagtg atttagtaaa ataagaaaat aaaataattt
    34681 ttcttgcttc ttggatactt taagtgcaaa atgttcgttt attttttgag gcactacccg
    34741 ttgttgaacc tcgggtagtg cctctttttt attgaaagga atcaataaga tttgattcct
    34801 ttatttatca ataggttata attcatattt ttttattttt tcttttacga tacttagtcc
    34861 agaagctaaa atttcaaggt tattagagga tagggaaatt cgaacgaatg catctggttg
    34921 cgcacgtgta gtaaagcgtc tggaatgata aagtcggata ccgttagcaa gaaagtcatt
    34981 ctcaattatc ttagggtcaa tctcaggatc aactggaaga attcgatagt aagggacacg
    35041 attcgttggt ttttctactt tgaaaagaga atcaaaaagc tgattggctc tttttgtaag
    35101 acttaattta gtttctaaga tcctatttgc ttcatttgaa tggaggattt gagtgatgac
    35161 ttccacatct aatccagaag ttttcacatt tatattaaaa attgcttgtt ctatcttgct
    35221 ttggacatgt actggaacta caagataagc aactcgcaat ccagaacaaa taaattttgt
    35281 cattccagct aagtagattg tttggttagg taataaattt tggaaaggag gaatgatcgt
    35341 atgttgatag taagttgtta aaaatgaatg gatatcatct tcaataaccc atagaccttc
    35401 tttttcaatc acttcggcta attgctctcg tcttttgtga gagatttgaa accctatagg
    35461 attattacaa gaaggcataa gaaagacacc atgaatcttc ttttttctac attcctgaat
    35521 caatatatca ggtcgcattc cttgctcgtc aaaatcaatt ggaacgatct ctaaatgata
    35581 taactgagcc aattcaatga aattagcgta tgtatatcgg tctgttgcta ttctatcacc
    35641 tggagagaaa agtgcagaaa gtgtgatagc caatccattt tgaacaccgg aaacaataga
    35701 tagagattct aaggacggaa tgactccttg agtttttaac caatttgctg cagtagtcaa
    35761 ttgaaaattt gtgcctttgg gatcttggta attaagcaaa ccaacaagat ttgggttatt
    35821 actagttgat tgaataaacg ggacaacgaa tttattacat tcttcaaaag aactaaccag
    35881 accaaaatca atgatatgtt cggttacttc attggtagag atggtgatgg actcaaagac
    35941 attgggagaa ataaatgtgc cacttccaat attcgtatac agcaaacctt tctcaattcc
    36001 atatttataa gccttgccaa cggtagtaaa atttaaatct aaataatcag ctagctctct
    36061 ttgggagggt aactgagtgt ttttctgtaa tttattcttt aaaatatctt gttctaattg
    36121 ttgaatcaac gatcgataat aaggacgctt caatttttgt ttgtctggtc gccaagttaa
    36181 cgggtaattg tcataagaat taataggcat tttctccact ccttaaaatt gtataccata
    36241 caattttacc attgattgta ttgattttag aagttaatct tttgtgagga gggaattgtc
    36301 tatgaaaatt attaattttg aggaagtagt agcttctttt agttttgaag aagcgattca
    36361 agtaatgaaa aaatgttttt ttgattatga aagtggtaaa atcagccaaa atcctcgatt
    36421 ggtggaaatt ttacctgacg gaaaaggcaa aaatatgttt gcgatgatgc ctgcttattt
    36481 gggggagaac agatattttg gcacaaaagt cattaccgct tttccggata atcatcagta
    36541 tcatttacct tctcatttag gagagatttt cttgtttgat gctcaaaacg gactacccaa
    36601 agcattgata aacgcaaatg cagtcacctg gattcgaaca gctgctgtat ctgcgctggc
    36661 aacagattac ttagcaaatc cgcatgcaga aacacttgct ttaattggag ctggtcaaca
    36721 agcattgtcg catttgactg cgatttctac cattcgtccc atcactacag tgtttgttta
    36781 cgatatttta gaagaaagac gaaatacttt tatcgctaaa gctaaaaaac agtatcctaa
    36841 aataacgttt ataaatgcaa tatcagtaga agatgcagta cgtccagcgg aaatcatttg
    36901 tacgttgacc tctagtaaag aggcatttct tcaaaaagag tgggtaaggg aagacgcaca
    36961 tatcaatgct gtgggcacat ttactcctga tacaagagag ataagtacat cgttgatgga
    37021 aacttctcaa atctatgtag atgattactc agctgcctta acagaaagcg gggacctgct
    37081 tatagccatg gcagaaggag atttagagga atcttgtatt gttggtacat taggcgaatt
    37141 agtttctgag aaaaaaacat tttataaagg agaatcgagg ccgacgattt tcgacgcagt
    37201 tggtctagct attgaagatc tttgttgtgc agaatatatt tataacaaat tagagaaagg
    37261 ggctttaaaa tgaacttaga ttattacgta gttgatgcat ttgcagatga ggtgttcaaa
    37321 ggaaatccag cagcggttta tgtgctagaa gaatggctgc cagaaggtac gatgcaaaaa
    37381 attgccattg aaaacaattt atctgaaaca gcatttacag tgaagaaaaa ccaagaattt
    37441 gagcttagat ggtttacgcc agatcgagaa atcgatcttt gtggtcacgc gacattagca
    37501 acagcatttg ttttatttaa ctattacaaa atacctgatg aaacgattaa attttctact
    37561 caaagcggta atctatttgt gacaagaatt aaagattatt attacatgga ttttcctagt
    37621 attatgccga aaaaagtgcc gatattgtct gaatatgaag aagcgattgg ggctaagatt
    37681 aaagaagcct acttagcacg tgatttattt ttcgtattag aagatgaaaa aacggtggct
    37741 aaattgcagc cagattttac agctatcaaa aattttgaat taggaatagg agtcatcgtg
    37801 acagcagaaa gtgtgcaaaa agactttgtt tctagaacct tctttccaaa attaacaatc
    37861 aatgaagatc cagtatgtgg atcagcacat tctaatctta ttccttattg ggcagaaaga
    37921 atgaataaaa caaaattgtc agcttatcaa atgtcatcaa ggggcgggga tctagaatgt
    37981 gaattaaaag aagatcgtgt gataatagga ggaaaagcag ttttgttttc taaaggtacc
    38041 tcgtttattt gatttctttc aaatgaatta aaaataaatt ggtggagagt ggcaacctta
    38101 tagctacaat ggttgttaaa aaaagacgca aactttttca atttaatgaa aagtttgcgt
    38161 ctcattttaa ttattggtgt ttgtttttta ttcaatcaag agtaaaatgc cccatactaa
    38221 ctatcctcgg atgacttcga ttttataacc atcagggtca atgacaaagt agtaagaagg
    38281 cgcagtgcca ggtaatcctt ttaagtcagt aatctcaaga ccagcagctt tatgttgctc
    38341 gtgtaatttt tctagatcat cagctgctat agcgatatga ccatagccgt ctcctagatc
    38401 atacgcacca tgatcatagt tgtaagtcaa ctctaattca tagtcatccc caggaagtgt
    38461 caaataaaca agtgtaaatt tgttttctgg aaaatcacgg cggcggcttt cttcaaaacc
    38521 aaatgccttt tgataaaatt cgattgatgc ttcaagatct ttcactcgaa cacatgtgtg
    38581 agccattttc atagattcat ctctcctttt ccttttactc aatcataaca aaaagaagta
    38641 aggaaatagt tgatttgtgc ttgttcatga gaaatttctc atgtaaaatg gatagaaaat
    38701 aaaactgtta aggtggaaac tattcatgga taaaccaatt tttggtgaaa aaaagcaatt
    38761 tgctgattat caaacccgtt atgcagcata tattgtcata gaaagagatc agcagattgc
    38821 agtaatcgag gctccaaatg gtgctttttt tcttcctggc ggggaaattg aaggagaaga
    38881 gacgaaagaa gaagcgattg tccgtgagct gatagaagaa atgggaattg tggcagaaat
    38941 ttcttcttat ctgggagaag ctgatgagta tttttactcg aattatcgtg caacttatta
    39001 ttataatcca ggatatttct ttgttgctga ttcttggaag cgtataggag aaccaactga
    39061 aaagaccaat aaaatttggt gggtgagccc tcaagaagcg cttgtgaaat tgaaacgtgg
    39121 tagccaccga tgggcagtcg agagatggat cgaaaaaaat aaaaactgaa agaaagcgag
    39181 tagatcagct ttctctcagt ttttttattt attacagtac atattttttg attgcttcag
    39241 ctacaccgtg ctcgtcgttt gatgaagtga tgacatttgc tgcttctttg acaagagaaa
    39301 cggcatttcc cattgctact cctagaccag catattcaat catggataag tcgttctcgt
    39361 tatctccgat agccatgatt tcatcttgat caataccaag gtgctgtgcg agattcgcaa
    39421 ctgccgcacc tttacttgct tctttattta gtacttcgaa gtaatagggc gcacttttga
    39481 ccgttgtgta tttatcacgg aaagtttgcg gtaaacgcgc aattgctgca tctaaaattt
    39541 ctggttcgtc gatcatcatc attttgacga tgttcatgtc tggtgtcatt tcttcaggtg
    39601 ttcgatattt tagcggcatc ttgactaaac ttgcttcgtg gatcgtataa gcgctgatat
    39661 ctcgattagg cgtgtagatc gctttgtcat cgatcgaatg gagatgactg ccgacacggc
    39721 gtgccattac ttcgatctct aggaaatctt catgtgtcag tccgtgacgg gcgatgattt
    39781 tacctgattt cgtttgttgt acgagtgccc cgttataagt aataacgtaa tcattatctt
    39841 gaaaaaggtt caactcgttt aactgttcct ggacacctgg taagggacgg ccagtgcata
    39901 aaacgatcga aacacctttt gcaacagcag cggcaatcgc ttcttttact tcttttgtta
    39961 cttctctttt ctcatttaat aaagtaccat cgatgtcgat agcgactagt ttgatagaca
    40021 taatttcctc caatatattt taatttattt caatcaatgc gccattacgg atatggctgg
    40081 caaattcttg ataagtttcg tcaaataaat cataatgatc acgcaaggac ggatcaacca
    40141 tttcttttgg aaagaaaaat cgctcatctc cttgttcttg tcccgctaat gcagcaacaa
    40201 gctgactaac ctgtgataat tctatcaaag ttccgtcatt tcgcaaaatc tcgatttgtg
    40261 tgcgatgtct gccttgttct gggcgataaa aatcataagg tagatcgtag ctagaattca
    40321 cagcagtgta ataaacagga ttatatccga ccttttctac taacaaagtg agttcttgga
    40381 ctaattttga atcccggttg ccagaaaaag tagcagattt cagtggttta cgattcaaaa
    40441 aacgtttagc taaatcattt aaaataggat cagcagattc agaccattga gtaaagtaag
    40501 tgcccaagac cccatcatca agtttgaggt attcttctaa agtaaagctt ccgtcaagaa
    40561 atggcagaag taattgagaa tggagttcaa aactgctggc atcttcttga tacaactcgt
    40621 gtgcgcgatg aagcagatgc tccaaaatta cttccatacc acgggaaaca ggatggaagt
    40681 acacttgcac atacatttga tatcggctaa cgatataatc ttccactgca tgcatgccac
    40741 tcatggaaaa agcgatcccg ccttcataag gacgaatcac acgtaatatt cgggtaagat
    40801 caaatgttcc atattctgtt ccagtgaaat aagcatcccg aagcaaatag tccattcgat
    40861 ctgcatcgat ctgactagaa atcatttgga caacttgtgg gttggggtaa gttttttgga
    40921 tcacactagc taccttttca ggaaaacctt cttctactcg gttaagaatc tgatacactt
    40981 ctgtttctgg agaagtgatg atctctacag tgatggcttc atgattcgta tggaagatat
    41041 gttcaaatgt atgagagtaa ggaccatgac cgacatcatg caacagtgcc gcacataaag
    41101 tcaccagccg ttcctgatca tcccagcctc cgttgcctat tttttctttt gaaaaatttc
    41161 gagaaaagat atcgcagatt cgtcttgaaa tctcataaac gcctaatgaa tgagtaaaac
    41221 ggctatgttc tgctccgtga aaagtgaaag aagaagtgcc taattgttta atgcgtcgta
    41281 gacgttggac ttctttcgaa ttgatcaaat ctaagattac ttgatgctgg acatggatat
    41341 agttatggac tggatcacga aaaacttttt ccataggcag catttgatat ttataagggg
    41401 ttgtcataat gtagctcctt tatgttatta cgttgttcca ttctctggat ttggttgttc
    41461 cattgctcca gctggatttc tttttttagc cagtcggtag aatcctgtaa atcacttgca
    41521 gaatacagct tttcaaaagc ttttgcaaat gcttctttga cttcttttac aaaaaggggt
    41581 tggtcaagca gttcttcaag tgttgccatt gtagcaggat ccactgcagg atagccattt
    41641 gtaccaaagt cttcttttaa agcagattga taaaatcgct tcatgacttg cccacgtttt
    41701 tcctgattac cgttgacact taagtacatc ataacagaaa tcccattttt gatccgacgc
    41761 tgagcgatac cggcaaattt tttgccatgg atgcttaaat cataagttcc aggacaataa
    41821 gaatgggtga tttcgaatgc ttgtatcggt gcctttggaa aagcgtattt agtcaatagg
    41881 agcatttgct cgtaagcgtc atctatggtt attttttttg tgtcactttg ggggaaaatc
    41941 aaagaaatat tcaaaattcc ttcatctgat acgatcccta atccacctga atttctgatc
    42001 actggagcgt aacctgcatc ttccagtgtt tggatcccgt cacttagaaa aggagttcga
    42061 acatccttca tacctaagat gactgtgcag tcatattgcc agaaatgtaa aaagatttgc
    42121 tggtgttctt tagaatattc cgttaatata tctgttaatg caaaagggga aaagtcgttt
    42181 ttttgataaa tgtgctgatc tagtcgaatc gcagggttca ttcaaccggc tcctttgtat
    42241 aaattcatat tttctacaat attatactct aaaatcaaag agttgttttg gaaaaaaggt
    42301 tttctgtaaa aatggacaag ttggttgaca aaacaaaaga aactaggaac aatgtagcta
    42361 tgagaagtaa aggagaatga ataatggaat tatcacaagg aacaccgatt tcaatcaaat
    42421 tgcgtacaaa agtaaaacag caaggggaag tgcaagattt ttattttgat ttgaaagggc
    42481 aaatggtgac aattggcgat acgctgtaca tacgttataa agagattcag gaggagacgg
    42541 gcgatgagat tcctgtaacg atcaaattag ttccagatgg tcatgtacag ctgatccgtg
    42601 caggagaaat gcggatgcgt ttgaaatttg gctataaaga acggttagaa acatcctatc
    42661 gaacaccata cggtatgatc cagattgcta cttttacgaa agaactgcat gttagtttga
    42721 aagaccgtcc cacagcaggg aaggttcgaa tcgattatga tctgttcatg ggaccggaaa
    42781 aaatcggcga atattatttg accttggatt ttacagcgta aatataaaag aaaagtttga
    42841 ttttttgtgt ctgattttgt atgataagga gtagactgtg aaaggacgtg tcctgattgg
    42901 aaattagtgt atttgaaggt gcaaacaaaa gcgaattatc aatgatcgaa gtagcacacg
    42961 cgatcttaga acaacgtggc gatgtcatgg atttttctga tttagctaac cagatccaaa
    43021 actatcttgg gaaatcagac agtgaaattc gtgattcact cgcacaattt tatactgact
    43081 tgaatattga cggcagcttt atctcattag gggataatcg ttggggcttg cgttcatggt
    43141 atgctatcga ttcgatcgat gaagaagtaa accatggaat ggacgaagag gatgaagata
    43201 ctccacgtcg ccgtaaacgc aagaaagtca acgcctttat caatgatgat gaagacgcga
    43261 tcgattacaa tgacgatgac ccagaagata cagatctgac agaagaagat gacgatgatc
    43321 tgtttgatga cgatgatgat gaagatgaag aaatcgctgc ttataattct gacttgcaag
    43381 aaatcggagc agatgacccg acagatgatg aagaagactt gccaggaaat atcgaagaag
    43441 atttaagtat catagacgaa gacgatgatg atgaagatta tgaagaggaa gaattttctg
    43501 actctgaaaa agaataaaca ttattttctt acgagaggtt gtgacagaga cgatcagcct
    43561 atcagaataa ggaggtgtga cacgattttt gtcacacctt cttttttgta tataaaaatc
    43621 ccaagtaaat acataaaaaa taaaaaaatt gaaactttta gcgcaccttg tacgtcatat
    43681 taagtgaggc agaaaggagt ggagaatgat ttttactgga tataagaaaa aacggcagat
    43741 cgaaaaatac cgtcacctgc tgaatggact catcgaaact gattatcaaa aaatgttccg
    43801 tatcacgatg aattacgtac atgataaaga agaggcctta gatgtgatgc aagatagttt
    43861 tcataaagcc ctgaactatt ttgaaaaaga aaaagagatc gagcatttta gtgcatggtt
    43921 ttatcggata ttgatccgca cggcattaga tagttggcgc agacaaaaaa ggacgcctgt
    43981 ggacttattt gaaattcaag atatccccca acagttacct ttagaaactt ccgttgcaga
    44041 gctccatatg attttagata aaatagacag tccggaaaaa gagattctga tcctctactt
    44101 ttttgaagga tttcgtttga aagaaattgc gactatcttg gatatgaatg aaaacacagt
    44161 taaaacgaaa atgtaccgct cattgaatgc tttacgtcaa atcctagaat gaaggagaga
    44221 agagtgccat gtattcccaa aaagaaaatt taaaaaaact aaagaaaact tataaagaac
    44281 aagcaattcc caaagggctt aaagaggaga tccgccagcg ttttattatc gaagagcaat
    44341 catttataaa agcaaagcgg agaaagagac gtctccaagg gttcggagta tctttggcta
    44401 tcgtaatgat tacaacaagt agccttcttt ttaatagtca agttcgaagc tttgcagaag
    44461 atttacccat cttaggatca gtcattgaat tgatcttagg cgaacgcttt actgatcgat
    44521 ctgaaaaaat cgatattcag gtaccgaaga tcaatacaca aaatgagaaa gaaaataaaa
    44581 caattcatgg attaaatcaa aaatactttc gcgaaggaca agcagatttt gaaaaagctg
    44641 aaaaagaata tggaaatttt gaaacggatc attaccaagt tttgggagat tatcagaaaa
    44701 tcgtagacga taaccggttt ctcgtgattg aaaggcagat cacccaaaca gcagcagata
    44761 gccatgttga aaaaagatac gacacaatcg acaagaaaaa cagtgtccag ctctcacttc
    44821 cacttttatt caaagatgac acctatctat ctgttttgac aaaagaagtc aaacggcaga
    44881 tggccgaaca agtcaaggaa gatccatcta agtactattg gactgagcaa gatattcaag
    44941 aagggacgat agaaaaacca acacttgtta cgcctacacg aagtttttat ttgaacaaag
    45001 agcatcaatt agttttgact ttttctcaat acgaaattgc tcctggttat atgggtacac
    45061 cagaatttgt cattcctaag tccgtgacaa aaacgatttt ggcatcggaa gattatttgg
    45121 atcattagac gagaagtagt tgcgactagc agtttcaatt ttcaagtaag tacaagtaaa
    45181 taataagaag agaaaaagag aaagaagaga tatagtgaaa agaaattatt tagttatcag
    45241 tattattgct ttatccgtgc ttttgttttt cgaaattact tcggtggcct ccttgatcac
    45301 cgaagtaaaa ggacaaacac actcttcgga gcattcgtca caatctttca aacaatcaga
    45361 acaatcaacc attaaaagcc aatcaactga aacagctaac gtcaaagaag ccattcaaga
    45421 atcagcggaa aaggtacaaa gtcagtcatc acaatcaaca caagacagta caaaaacgag
    45481 ccgagatccg gctgtcaaaa gcgtcgcaat cagctttgat gatggaccag gagcgaccac
    45541 aacaccgcag cttctgcgaa tcttaaaaga aaaaaacgtg catgccactt ttttcgtctt
    45601 aggagaaaat acggcgcagc atcctgaaat cgtgaagcag acagctgaag cagggcacga
    45661 gattggcaat cacacatacg atcatcagaa tctggccact ctttctgccc agtcgatgac
    45721 ggaggaagtg acgaaagcag acactgagat caaaaaagtc actggcaaaa cccccacttt
    45781 tgttcgtccg ccctatggtt ctgtcacgaa tgtaggagca acgatcatcc agcgaccgat
    45841 catcgaatgg tctgttgatt cagaagattg gaagacaaga aatcctgatt tgattttgca
    45901 gaagatccaa gcaacagtat acgatggggc aattatttta ttccatgata tctatcctga
    45961 aacgattcgt gccgttcctc aagtgatcga ttatctgaaa gagcaagggt atcgcatcac
    46021 gacagttggg gatttattag ggcatccaac ggctgtcgag aactattatg gcagaaacga
    46081 tcatcggcca gttcagtaag tgagacaagt atctttaata aataacacat tttaataagt
    46141 agttgaacac ataactacct tacttgcaaa ggcttaacaa tatctataca ggtacaacaa
    46201 aaaactgtcc accaatttt
//
LOCUS       DAZULR010000023        45418 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.023, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000023 DAZULR010000000
VERSION     DAZULR010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 45418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45418
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.023"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..407
                     /locus_tag="ACG8ZV_001401"
     CDS             <1..407
                     /locus_tag="ACG8ZV_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFS4996752.1"
                     /translation="NQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSLD
                     LDGVYINKGEQVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFKL
                     PKAVGKLLGSIQTNLPESVLLDCGMDFLKDIC"
     gene            465..2504
                     /locus_tag="ACG8ZV_001402"
     CDS             465..2504
                     /locus_tag="ACG8ZV_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HFS4996753.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKIAFDSLGGKAASTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFKTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(2613..3764)
                     /locus_tag="ACG8ZV_001403"
     CDS             complement(2613..3764)
                     /locus_tag="ACG8ZV_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFS4996754.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(3918..4448)
                     /locus_tag="ACG8ZV_001404"
     CDS             complement(3918..4448)
                     /locus_tag="ACG8ZV_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HFS4996755.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(4547..4897)
                     /locus_tag="ACG8ZV_001405"
     CDS             complement(4547..4897)
                     /locus_tag="ACG8ZV_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HFS4996756.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(5054..6583)
                     /gene="ahpF"
                     /locus_tag="ACG8ZV_001406"
     CDS             complement(5054..6583)
                     /gene="ahpF"
                     /locus_tag="ACG8ZV_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008785 - alkyl hydroperoxide reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000302 - response to reactive oxygen
                     species [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HFS4996757.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     RTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(6593..7156)
                     /gene="ahpC"
                     /locus_tag="ACG8ZV_001407"
     CDS             complement(6593..7156)
                     /gene="ahpC"
                     /locus_tag="ACG8ZV_001407"
                     /EC_number="1.11.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0102039 - NADH-dependent peroxiredoxin
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit C"
                     /protein_id="HFS4996758.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(7300..7962)
                     /locus_tag="ACG8ZV_001408"
     CDS             complement(7300..7962)
                     /locus_tag="ACG8ZV_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFS4996759.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            8146..9792
                     /locus_tag="ACG8ZV_001409"
     CDS             8146..9792
                     /locus_tag="ACG8ZV_001409"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HFS4996760.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            9783..10865
                     /gene="uxuA"
                     /locus_tag="ACG8ZV_001410"
     CDS             9783..10865
                     /gene="uxuA"
                     /locus_tag="ACG8ZV_001410"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFS4996761.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(10973..12526)
                     /locus_tag="ACG8ZV_001411"
                     /pseudo
     CDS             complement(10973..12526)
                     /locus_tag="ACG8ZV_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            12674..13815
                     /locus_tag="ACG8ZV_001412"
                     /pseudo
     CDS             12674..13815
                     /locus_tag="ACG8ZV_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(13941..15020)
                     /locus_tag="ACG8ZV_001413"
     CDS             complement(13941..15020)
                     /locus_tag="ACG8ZV_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFS4996762.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVIDFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(15129..15569)
                     /locus_tag="ACG8ZV_001414"
     CDS             complement(15129..15569)
                     /locus_tag="ACG8ZV_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFS4996763.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTSLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTPQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(15626..16036)
                     /locus_tag="ACG8ZV_001415"
     CDS             complement(15626..16036)
                     /locus_tag="ACG8ZV_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HFS4996764.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(16217..16651)
                     /locus_tag="ACG8ZV_001416"
     CDS             complement(16217..16651)
                     /locus_tag="ACG8ZV_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFS4996765.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVSFEERKQLFEKYM"
     gene            complement(16751..17599)
                     /locus_tag="ACG8ZV_001417"
     CDS             complement(16751..17599)
                     /locus_tag="ACG8ZV_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFS4996766.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAVLGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLFFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFVFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            17988..19754
                     /locus_tag="ACG8ZV_001418"
     CDS             17988..19754
                     /locus_tag="ACG8ZV_001418"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HFS4996767.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETRRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVRDHLDYLTDLGVNGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVYDREDKLYFTRELEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            19856..21115
                     /locus_tag="ACG8ZV_001419"
     CDS             19856..21115
                     /locus_tag="ACG8ZV_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFS4996768.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            21262..22563
                     /locus_tag="ACG8ZV_001420"
     CDS             21262..22563
                     /locus_tag="ACG8ZV_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4996769.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            22566..23417
                     /locus_tag="ACG8ZV_001421"
     CDS             22566..23417
                     /locus_tag="ACG8ZV_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HFS4996770.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            23430..24245
                     /locus_tag="ACG8ZV_001422"
     CDS             23430..24245
                     /locus_tag="ACG8ZV_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HFS4996771.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            24396..25562
                     /locus_tag="ACG8ZV_001423"
     CDS             24396..25562
                     /locus_tag="ACG8ZV_001423"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFS4996772.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            25792..26439
                     /locus_tag="ACG8ZV_001424"
     CDS             25792..26439
                     /locus_tag="ACG8ZV_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HFS4996773.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            26523..27467
                     /locus_tag="ACG8ZV_001425"
     CDS             26523..27467
                     /locus_tag="ACG8ZV_001425"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HFS4996774.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            27602..29053
                     /locus_tag="ACG8ZV_001426"
     CDS             27602..29053
                     /locus_tag="ACG8ZV_001426"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HFS4996775.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            29074..29910
                     /locus_tag="ACG8ZV_001427"
     CDS             29074..29910
                     /locus_tag="ACG8ZV_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFS4996776.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            29910..30569
                     /locus_tag="ACG8ZV_001428"
     CDS             29910..30569
                     /locus_tag="ACG8ZV_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFS4996777.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSIHQS
                     I"
     gene            30695..31384
                     /locus_tag="ACG8ZV_001429"
     CDS             30695..31384
                     /locus_tag="ACG8ZV_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996778.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PKDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            31390..32346
                     /locus_tag="ACG8ZV_001430"
     CDS             31390..32346
                     /locus_tag="ACG8ZV_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HFS4996779.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            32390..32902
                     /locus_tag="ACG8ZV_001431"
     CDS             32390..32902
                     /locus_tag="ACG8ZV_001431"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4996780.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSGVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(33158..33706)
                     /locus_tag="ACG8ZV_001432"
     CDS             complement(33158..33706)
                     /locus_tag="ACG8ZV_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFS4996781.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(33795..34976)
                     /locus_tag="ACG8ZV_001433"
     CDS             complement(33795..34976)
                     /locus_tag="ACG8ZV_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside transporter C-terminal
                     domain-containing protein"
                     /protein_id="HFS4996782.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(35212..36720)
                     /locus_tag="ACG8ZV_001434"
     CDS             complement(35212..36720)
                     /locus_tag="ACG8ZV_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HFS4996783.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATCLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            36879..37070
                     /locus_tag="ACG8ZV_001435"
     CDS             36879..37070
                     /locus_tag="ACG8ZV_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996784.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            37273..38190
                     /locus_tag="ACG8ZV_001436"
     CDS             37273..38190
                     /locus_tag="ACG8ZV_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coiled-coil domain-containing protein"
                     /protein_id="HFS4996785.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            38183..39256
                     /locus_tag="ACG8ZV_001437"
     CDS             38183..39256
                     /locus_tag="ACG8ZV_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996786.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            39404..39922
                     /locus_tag="ACG8ZV_001438"
     CDS             39404..39922
                     /locus_tag="ACG8ZV_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996787.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            39903..40295
                     /locus_tag="ACG8ZV_001439"
     CDS             39903..40295
                     /locus_tag="ACG8ZV_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HFS4996788.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVVFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            40371..41306
                     /locus_tag="ACG8ZV_001440"
     CDS             40371..41306
                     /locus_tag="ACG8ZV_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFS4996789.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            41439..42218
                     /locus_tag="ACG8ZV_001441"
     CDS             41439..42218
                     /locus_tag="ACG8ZV_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HFS4996790.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            42211..42528
                     /locus_tag="ACG8ZV_001442"
     CDS             42211..42528
                     /locus_tag="ACG8ZV_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HFS4996791.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            42772..44382
                     /locus_tag="ACG8ZV_001443"
     CDS             42772..44382
                     /locus_tag="ACG8ZV_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFS4996792.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            44539..45387
                     /locus_tag="ACG8ZV_001444"
     CDS             44539..45387
                     /locus_tag="ACG8ZV_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFS4996793.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
BASE COUNT        15069 a         8186 c         8728 g        13435 t
ORIGIN      
        1 taaatcaaac attaaaggaa aatttcaaat ttgaagctcc ctattatgca agtatcacat
       61 ttcaagattt tatcgattgc gttaatgaac tgtttcctgg tggagtcaag atcgatgcag
      121 aaaaatctct agatttagat ggcgtatata taaacaaagg agagcaagtg atggatggta
      181 atactttact ccagtatgct cgatttcggg aagacaaaga aggagacttc gggaggatca
      241 gaaggcagca gcaagtgatc aaagctatct ctcagcagct gaaagacgta acttcaatat
      301 tcaagctacc caaagcggtt gggaaattac ttggtagtat ccaaacgaac cttccagaaa
      361 gtgtgcttct ggattgtggt atggatttcc tcaaagacat atgttagaat aaacaggtat
      421 aaatagtgaa ataaaggaat gacaagcaag agaaggagga aaaaatgaaa agaagtgaca
      481 agcacggcaa aaatcgaaca ggcgcttata ttgccggcgc agtgatctta atagcagctg
      541 cgggtggcgg ttatttttac taccagcact atcaagaaac ccaagcagta gaagctggag
      601 aaaagacagt tgagcaattt gtccaagctt tgaacaaggg agattataac aaagctgcag
      661 aaatgacatc aaaaaaggcg gcaaataaaa gtgcattatc tgaaaaagag atcttagata
      721 aataccagaa tatatacggt gctgctgatg tcaaaggact tcagatatcg aatctaaaag
      781 tagataaaaa agacgattct acttacagtt tttcatataa agcaaagatg aatacctcat
      841 taggtgaatt gaaagatctt tcttataaag gaacattaga cagaaatgat ggtcaaacca
      901 cgatcaactg gcaacccaac ttggtttttc cagaaatgga aggaaatgac aaagtaagcc
      961 tgaccacaca agaagcagca agagggaata ttatagatcg aaatggtgaa ccattagcaa
     1021 caacaggcaa actaaaacaa ttaggagtcg ttccaagtaa acttggagat ggaggcgaaa
     1081 aaacagccaa tatcaaagcg attgcttcct ccttcgactt aacagaagat gctatcaatc
     1141 aggcgatttc acaaagctgg gtacaacccg attactttgt cccattgaaa atcattgatg
     1201 gagcaacgcc agaacttcca gctggagcta ccattcaaga agtagacggc agatattatc
     1261 ctttgggtga agcagctgct cagctgattg gttacgtggg agatatcaca gcagaagata
     1321 ttgataagaa tccagaatta agcagtaatg gaaaaatcgg tcgctcaggt ttggagatgg
     1381 cttttgataa ggatcttcgt gggacaacag gtgggaaatt aagcattaca gatgcagacg
     1441 gtgtagagaa aaaagttctg atcgaacatg aagttcaaaa tggcaaagat atcaaattga
     1501 caatcgatgc gaaggcacaa aaaatagctt ttgacagtct aggaggaaaa gctgcatcaa
     1561 ctgttgcgac aacgccaaaa accggtgatc ttcttgcgct tgctagctct ccaagctatg
     1621 atccaaacaa aatgacaaac gggatctcac aagaagatta caaagcttat gaagaaaatc
     1681 ctgaacatcc attcatcagc cgatttgcga caggttatgc tcctggatct acgtttaaaa
     1741 tgattacagc agcaatcggt ctcgacaacg gcactatcga tccaaatgaa gtgttgacga
     1801 tcaacgggct taaatggcaa aaagacagtt cttggggatc ttttaaaaca acgcgtgtca
     1861 gtagtgatgt atcacaagta gacttaaaaa ctgctttgat ctattccgat aatatatatg
     1921 cggcacaaga aacgttgaaa atgggtgaga aaaaatttcg tacaggctta gataaattca
     1981 tttttggtga agaccttgat ttgccaatta gtatgaatcc agcacaaatt tctaatgaag
     2041 atagctttaa ctcagatatc ttgctagctg atactggata tggacagggc gaacttctaa
     2101 ttactcctat ccagcaagca gcaatgtatt ctgtttttac caacaatggc acacttgtct
     2161 atcctaaatt gattgcagat aaagagacaa aagataagaa gaatgtcatc agcgaaacag
     2221 cagtacaaac gatcgtgcca gatctgagag aagttgtgca agatgtaaat ggtacagcac
     2281 attctctttc tgctttaggg attccgttgg cagcgaaaac tggtacagcg gaaatcaaag
     2341 aaaaacagga tgtaaagggg caagagaaca gtttcttgtt tgctttcaat cttgataacc
     2401 aaggttatat gatggtcagc atgttggaaa ataaagaaga tgatgattca gcaaccaaac
     2461 gagcatcgga actattgcaa tacctcaacc aaaattatca ataaaaaatt gctttttaag
     2521 tacagtaaaa ggactgtggc gttatcgtca cagtcctttt ttcaaataaa cggttttcac
     2581 gatgtctctt tcacaacttc tttttgattt actcacactt cataaacttt ttttgtaaaa
     2641 tatttgagaa caagtggaga aataagtgta cttaataaaa tcacgataac taaaggtgaa
     2701 tagtactgtg gttcgatcaa ttgactttgc tgtccaattt gtaaaatgat caaagccatt
     2761 tctccacgcg aaatcatacc agcaccgacc atcaatgaac tatgttgaga aaaaccggca
     2821 atctgagcac caaaataacc tccaagcaat ttggtcaaaa tcgctacaag cgtcaatata
     2881 gaaataaaga gtagttgttc actaaagtca gaaaaatcaa cttctaatcc tacactgaca
     2941 aaaaatactg gtataaatac tgcatatcct aaagcctcta cattgtggta tacttcttct
     3001 ttaacctttg tctgactgac agctatccca gcaaaaaaag caccaatgac agagctaagc
     3061 ccaacaagat ccgctacgta agacattcct aaacaaataa ctagcgatac gatgataata
     3121 gaagaatttg cgtacacttt ttctgcaaat gaaagtagga aaggcgcaat ccatttgact
     3181 aataagaaaa taaaaacaaa ataaattagc tgttcaatca aaacaagcgg taaagaagca
     3241 ttgctagaag cttcccccgt tagaaaagat aggctgaaac ttagaactaa aacgactaaa
     3301 atgtcatcta ccacagaagc acccaaaatt gttgatcctt cttttgtatt cactacgttt
     3361 agttctttta atacttctac tgaaatactg acagaagttg ccgcaagaat aatcccaaag
     3421 aaaatcgctt catttcccga aacttggaat gctttgcctg tcaaccagcc aaaaacaacc
     3481 gggaagatga tcccaagcaa agcaacgaac ataccaggtc ggaaatattt tttcaaaaga
     3541 gataaatcac tttccagacc agctaaaaac attaataaga tcacaccaat ctccgaaaag
     3601 tcatggacta gaatatcagg tttgacccaa ttcaatccag cttggcctag caaaacacca
     3661 acaagtaatt gtccaatcac tgctgggata cctaatctcc gcgagatatg tgagccaatc
     3721 gttgttgaaa tcaatatcag gcataaaata ccaataaatt ccattctcat cattcctttg
     3781 tataaaatat agcccgaact tagcataaca tacattattg aaaaaatagg aaaatatact
     3841 cacaaaaaaa ccaacaatcc aaaagatttt tttggattgt tggtttttat acggtctatt
     3901 ttaataacta aaaatgatta acgtatagtc atttttctta ttctgatgaa attgataatc
     3961 tcctggatgc ccatgaaaat caaaataaag ccgaatattt ggaatagaag catcaaactt
     4021 ttgaatggat tgaacaataa gacgaatccg ccaatcaaca acagaatact actataaaca
     4081 ctccaacttt tagcttttgt attcatgctg aagaacaact ggaacaagct gttgatgata
     4141 acagctaatc caagaagaat cggcaggata gaaacgattg caggtgcaaa agcatagacg
     4201 atcagagcta agatcaggaa aaaaagacca ctgaacagac cgatactcca agaacctgtt
     4261 ttccttttaa aacggtaagc ctcaaaaaga ttcaacaacc caagcaaaac aagataggcg
     4321 gtgatcagat aaccgataaa atgaaaaaca gcagaagggt ttagcacaat cgcaatccca
     4381 gaaataatat aaacagcagc tcttaataag gcgtattttt gaatattttg tttaatcgtc
     4441 tcaaacatat aagaaaacct cctttgactt attttaacgt gaactagtca ttttaccaaa
     4501 ttaaatgtta caaaatgagc gaaggagaag aatatctctg gaaaaatcaa cttctgagga
     4561 tcttttccat ttttttgcct tttgctagct catcgatcat tttatctaaa taacgaattt
     4621 ctttcatcaa gttatcctcg atgtcttcta ctcgtacacc acaaacaaca cctgtaatca
     4681 aggaacgtga aggattgggg acaggggctt ccgcaaaaaa ttgttcgaaa gtcacttgtt
     4741 tttgtagttg atattctagt tctgtttggg aataacccgt cagccaacaa atgatttcat
     4801 ctacttcctc ttttatacga tcttttctct ccgcttttgc tacatacata ggataaacgc
     4861 ttgcaaaact tgtcgtaaaa atacgatttt gcgccataat cagtcacctt tctttttttc
     4921 aaattattta ctacttatag tatataagaa aaagagaaga aaaagcgatt attcaaaaaa
     4981 acaaaaagga ttgtgacaaa attcttgtca ccatcctttt ttccgctctc tgacttttta
     5041 caatcttcat agctcaagtg cgcatcagat aatcgaatgc tcctaaagct gcagtagctc
     5101 ctgaacccat tgaaacaatg atttgtttgt atggactatc tgtacaatca ccagctgcga
     5161 aaacgccggg gatattcgtt gcgccatttt tctcggtcac tatttcattt cttggattca
     5221 tttcgatcgt tctatctagc caatccgtat tagggagtaa gccgactaga atgaatactc
     5281 ctgaaacagc tagtgtatgc atctccatcg tacggcgatc gatataggag agagattcta
     5341 cctgattcgt accgctgatt tctttcgtcg ctgcatgttt gataacagtg acattcgcaa
     5401 gagagactag tttatcctgt aagatttgat ctgcttttaa ttctggtaag aattctagaa
     5461 catatacatg ttttgctaac ccagccaaat cgattgctgc ttcaacacca gaattaccac
     5521 caccgataac agcaatctct tttcctttaa ataaagggcc gtcacagtgt gggcaataag
     5581 caattccttt atttttaaac tctttttcgc ctggtacatt gatagaacgc cagtgcgcac
     5641 ctgtcgcgat gatggcggtt tttgctttaa gtgatatacc gttagctaag ccaatattaa
     5701 taaaatgttg ctctttattt aaggaaacgg cctgttgatt catcataatg tcgatagggt
     5761 aactacgcac atgactttct acttgctgca tcaattttgg accttctgtg taagaggtac
     5821 caatcatatt ttcaatccct agtgtttcaa cgacttgtcc gccgaaagaa tcagcgacaa
     5881 gtcctgtacg gattccttta cgtgctgcat agatagctgc actactagct gctggtccac
     5941 cgccaatcac taatacatca taaggttctt tttcaaacaa ctcttcttca atcaaagggc
     6001 cagtgatttt ttcaacaatt tgttcgatcg tcatgcgtcc gctactaaat tcttctccat
     6061 ttaaaaacac agttggcact gccatgattt ttttatcatc gatttctttt tggaacatcc
     6121 caccttcaat catcgtatga gtaatatttg gatttaatac agctaatata ttcaatgcct
     6181 gtacaacgtc ggggcaatta tgacaagtca agctaacata actgtcaaaa tgcaatgttt
     6241 gtgttatttt tttgatttta agactcaaag attcactgat tttcggtgcc cgtccactaa
     6301 tttgtaacat agccagtaaa aaagaggaaa attcatgacc gagggggata ccagcaaaaa
     6361 cgattccact ttctttgcca actggattga tagaaaaact aggtgtgcgc atcgaatctc
     6421 ttttttccca agagatttta ggagacattt ctgctatttc cttcgtaaat tcagctagtt
     6481 tttgactatt ttcactatta tccaaactaa cagaaaaaac aataggagat tcaatcagtg
     6541 ctaaatattg ttcgagattt tgtttagttt ctttgtctaa catatccacc acctaaatct
     6601 ttccaacaag atcaaaactt ggtttcaatg tttcgccact ttctttccat tttgccggac
     6661 aaacttcacc tgggtgggta cgtacatatt gagcagcgcg aatcttatca atcagtgcac
     6721 tagcgtcacg accgattcca tctgcattga tttccatagc ttgaacgatt ccgtctggat
     6781 caataataaa tgttcctcgc tgagctaatc cttgctcttc atccaaaaca tcaaaaatac
     6841 gagaaatctg atgagacgga tcaccgatca tcacgtattc gattttaccg atagcatctg
     6901 atgtatcatg ccatgctttg tgagtaaagt gggtatcggt agagcaagaa aagacttcaa
     6961 cacctaaaga tttcaatgta ctgtattgtt cttgtaagtc ttctaattca gtaggacaaa
     7021 caaaagtaaa atcagctgga tagaagcaaa gaatactcca gttccccata agatcttttt
     7081 cactgacttc taaaaattct ccttgatgat aagcatgtgc attaaattct tcgatttttt
     7141 tcccaatcaa tgacatagta aaacctccaa taataattat ttatttataa ttattgtaat
     7201 ttagttggag ttgcaaagtc aatggatatt ttgttattta ataaagatta ctcaaaaacg
     7261 aaggttaatt ataaaaatag aagaggtcgc aagaaaatgc tactgctgga aatactcggg
     7321 ataacgttga gtaacagttt cctgttcttt cagcatcatg tgtaagtgca atcccgtttg
     7381 aaatcgagct tcttctggtt ttttatcaac taaagccttg agtaaatcat aatgttgttc
     7441 catgatcgtt tcccatggaa gcccctgaat ggtcactcgt aaccagcgga aacgttctaa
     7501 atgggtatta tggtcatcta accagttcca aacttctttt cttcctgcaa tttcgaaaca
     7561 agcttcatga aataaattat ctgcacggaa aaaagcgcgt tcgtcattta ttttgactgc
     7621 tttttcttgt tcttctaaaa tcgtttctag cactattcgt gtttgtgtgt ccaatttgga
     7681 acaacattca atcatgattt gctcttccaa ctgttctcgg acaaagcgag cattttctgc
     7741 agaaacaaga ttaattttgg aaacatacgt accactttga ggtatcgtat acacgagttc
     7801 ttgctgacgt agttgaatca atgcttcgcg aatgggagtc cggccgatag caagatgttc
     7861 ctccagtgcc ttttcagata ttttccttcc aggttctaag tcagcataga taatttgttt
     7921 acgaatcgct tgataagctt gtgattgcaa gctgcttttc atctttattc ctccaaaatc
     7981 atttctatga acgtagtata acagaagagg tctgaaaaac aatctggtat gtcacattaa
     8041 ctagtaaatt tgtataaata gtaaaatttt ggttgacata gcgattttta ttgcataaaa
     8101 ttcacttgaa tacaaaaact aatatgttag tttaggaggg gaaaaatgat tgatttaaac
     8161 aactggagga actttatccc tgaattatct caaaaagaag tagaaatacc tcattttgac
     8221 cgtgcatcat taagagaaaa tggacaaaaa aatcctgtct ggatccattt cggtggcgga
     8281 aatctttatc gaggatttca tgcagaaatc gctcaacgtt tagcggatct aggcgaattg
     8341 tccactggtg tcattgtttg tgaaacattc gatgaagaaa taattgaaag ggcttaccaa
     8401 gattttgatg atttgattct tgaagtggtc atgccaagca gtggagagtt cgtcaaacgt
     8461 atattagctg cgacagctga cagtctgtat tgtcatccag attgttctga acactttgat
     8521 aagatgattc gacactttga aaatcctagt ttacaattag ttacttttgc tattactgaa
     8581 aaaggttatc gattgaaaga tacaaataat aaatatatag gaccgattgc agtcgatata
     8641 aaaaatggtc caaagaagcc atcacataca atgagtattc ttgctgtgct actttataaa
     8701 cgttttttat ctggagcttg gccgattgca cttgtctcta cagataattt ttcacaaaac
     8761 ggtagtcaat tacgtacttc tttgctaacg atcgcaaaag aatggcaaaa ggaaggttat
     8821 gtacaaaata catttatcca atacttatcg aatgaagaaa ttgttgcgtt tccatggacg
     8881 atgattgatc gtatcacccc gaatccttcc ttgtcagtta gcaaaatgtt ggcaaaagag
     8941 ggcttttcaa atatgtcgat tttccaaacc gcaaaaggaa ataatattgc tccatttgtc
     9001 aatacagagg acatccatta tttaatcatg gaagatcatt ttcccaatgg acgtccgaaa
     9061 ttcgaaaaag ctggggtatt cttgactgat cgtgcaacgg tagataaagc agatacgatg
     9121 aaggtgacga cttgccttaa tcctttgcat acgtctttag ctattatggg ttgtttactg
     9181 gggtatagga gcatagctga ggagatgaaa gatccagatt tatcgctgct agtttctgaa
     9241 atcgggtaca atgaaggcct cccagttgtg gagtctccag gtatcattga tccaaagatc
     9301 tttctggaag aagtaattac tgtgcgcttt tctaatccaa atattcctaa tatgcctcag
     9361 cgaatcgcca cggatacctc tcaaaaggtg gcgattcgtt atggtgagac gattaaaaaa
     9421 tatatggaaa tagaagttaa agacccgcag acacttgtat tcataccatt gactctcgct
     9481 gcttggcttc gataccttat tggcattgat gatcaaggaa aaccattcat cccgagtcca
     9541 gacccactat tgacagacct tcagcataag ctttccgata ttcaactggg tacgcaagat
     9601 acatcacata ttcatgagaa aatggctcct attttgtcaa ataaagaaat ttttggtgta
     9661 gatctttacc aagcagagct tggcagaaaa atagaagaaa tgttcatcaa gatggtagca
     9721 ggaccaaatg ccgtacgaaa aacattacag gattacttac aagaacatgg aggaaattta
     9781 tcatggaaat gacttttaga tggtacggat cacaggaaga aaagattacc ttagatgaaa
     9841 tcagacagat tcctgcggtc aaagggattg taggcacatt gatggatata ccagtaggag
     9901 aggtatggcc tagggagagg atcaaagaac taaaagaaga aattgagtct cgtgggttaa
     9961 cactaaaagt aattgaaagc gtcaatgtgc atgatgccat taaaattgga ttaccttccc
    10021 gtgagcagta tatcgaaaac tataagcaga caatccgaaa cttggcagaa tatggaatag
    10081 aagtcatctg ctataatttt atgcctgtat ttgactgggt gaaatctgac cttgactacc
    10141 gcttagaaga cggctcatcc acgttagctt ttatatctga tgatattcca gatgatccaa
    10201 gagaaatcgt cgcgcgcatc gaacattcca gcaatgaatt tggattgccg ggatgggaac
    10261 ctgagcgctt agctcctatc aaatccttgc ttgaagccta tgcatcagta gacgaagaaa
    10321 aacttcgaga aaattttgcc tattttctcc aatcaatcat cccaacatgt gaagaggtag
    10381 gggtcaaaat ggctgtacat ccagatgatc cgccatactc gatttttgga ttagctcgaa
    10441 tcgtaaagaa tcgagaagat ttagattggt tgtgtcgcat agtagacagc ccttataacg
    10501 gaatcactct ttgtacaggg agtattgcag aagatccaga aaatgatgta tatgggattt
    10561 tagcagaatt ttgccaaaga gatcgaatcc catttgcaca tgttcgaaat attaaatttt
    10621 tagctaatcg agatttctat gaggcaccac ataaatccga atacggttca ttagacatgt
    10681 accgcatact aaaaacaatg tatgacaacg gatttaacgg atacatccgt cctgatcatg
    10741 gaagaatgat ctggaatgag acaggaagac caggatacgg cttatatgat cgagcattag
    10801 gtgctgttta tctaaatgga ttatgggaag caatcgaaaa aggaaacaaa agtaaagata
    10861 attagtgaaa aaaactgtaa ttttattatg taaataagaa ggatgttcaa attcttgata
    10921 cataaatccg gaggttgtta ataagcattc ggatttatgt atcttatttg gtctaggaag
    10981 taacttgatt ttcttttttc gattgatcca tgagtgcttc ttcttttaat tcaaagatat
    11041 attctgagat cctcataatc acttttttcc agtcttctgg tgtgatgatt ccttttaaaa
    11101 tatagatttt tttgatatga gaaggcaatt gtttcaaagg gcagtcgctg ataacgatgt
    11161 tgcagttctc cataaaatca ttttgtattt tgatcgattc atttgaaaaa atttgttcta
    11221 tcttaacgat cagatcttta ctgatataaa aatcacgcgt atagttcaca ccaatcacaa
    11281 ttcgcggctg ttttttgtag cgatcataca aatgtactag gtcttcaacc atccattgca
    11341 cattttcctt ttctaaaata actggtaaca agtgttgatt ttgttctctg aaatccatat
    11401 aaaattgttc aatggcggtt tggacttctt tcaatacgct atgttcttga taaagcatga
    11461 aagtaggaag gggcgtattt ggttgattga agttaagaaa tccattataa agtttatttc
    11521 gtgcgaatgc caatgagtaa agaatctttt ctttttcagg tataaacaaa tcaaatacag
    11581 tacaaaggga ctccaccatt tctcttgaat aaagaacatg aggaacgttt gcttttttta
    11641 aaagtttgta ttgctccaag cttgtttctt ccgattcgat tttcgtgata gaaagtcgag
    11701 ctaaaatatt cactaagatg cgttgttcgc gacaaattgg cagattaggt cgcaaaatat
    11761 ctacagagag atcaataaaa aagtcaatat attcatactc tgtgaattct ttttgtacgt
    11821 ctttcacaga agttgcagga aaattctctt tacatatttt taatagaaaa tataatttat
    11881 ctatcatacc gctatttagt cggtcaagta cttctttttt aaaaaaagta ttcatcataa
    11941 aagccactac ttgcggatct tcatcataaa attctgtagc agtacttgaa aagatgttcc
    12001 aataaatatc taatgctgca tattgaattt gtacctcttt tccagaaaaa gactttctgc
    12061 cattattaga aaaggagata gacaaaccgt actatgctaa aaatgcatta atctttttca
    12121 ttttcgtata caaataagag gcactatagt ttgtttgctg actgaaactg ataatcgaat
    12181 ttgtctgaca gctgaacaaa gaagtcaaga tctgataact gactgattcg ttgcagtatc
    12241 ttccaaatag acgataatag cagtaagccg gatcaattcc ttcaaaattc aactttaaaa
    12301 aaggtttttg cttatcaata tgcagttctg ttagattgag acgctcaaag tcttgttcta
    12361 attctttgat gtatagtaaa aaatttgatt cagacatatg gaaatgatct gctaaatatt
    12421 gtgtagtaat aaagaaacga tgttcagata ggaaaagaaa aatatctaat tttgtattgc
    12481 tttttttctt caagataaac gttttaatcg cttcttgagt ttgcatgaaa gaggctcctt
    12541 tttacttaaa ttgttaaaac ttgaaaatat tactgttttt ttcataaatt tagacaaaaa
    12601 aacagtaaac atataggtag aatctctact atcttatttc ttgcatacaa aaaaatcaag
    12661 gagtgagaga gttatgagat attcaaccat cttaatatca acatttgcag ccttaagctt
    12721 atcgcttact ataaatcaga cagtccacac agaggagaca gaaacagcca aatggacaga
    12781 aaccaagtgg gccaacgtca atcgaattac ctttcaggat gaattttcat ccttcaattc
    12841 aggagtcgca aaattaagaa aaggacaaac agcgaccatc aaagcaaaaa ttgactattc
    12901 gggagactta gcacctatac tacaatcagc tgttacattt gagaatgttg atcccacttt
    12961 gtcgattggc tatgacgaga acactttgac tatccaacac aagcaagcga tatttacctt
    13021 caccgttaca ttaaatcagg acttgttaaa accagcgctt tttactgtca aggtatcaga
    13081 tggactaccg aacgatcatc atttaacgcc gtatagtcag cggcagacaa ttgagcaaga
    13141 ttcagccatc gactcaggag gagatcttgt tgaagaacca acagataaac cagaaaatga
    13201 aaataagcca gaagtaccgc ctacagaaaa tccagacgga gaacagaaac cggaaataga
    13261 acctggagaa gaacccgata cagaaactca accagagcca gacaataaat caaaacctga
    13321 aataacccct ggagaaaaac cagatgtaac tccagaacca gatacggatt ctggaaacca
    13381 aacagtaccg gaaacaaatc cagacacaga taatgaaact gaaaatccag aaaaaccaga
    13441 ggtagatcca gaagaaaaac cagatgtgac tccagaacca gatacggacg caagagacca
    13501 aggaatacca gaaaaaataa acaaaaaaac aattcaagag gatggaaaaa aagagagtaa
    13561 aaaatcaaat ctagcaattc taaaaataaa tgaagagcag ctgaataaaa aatcacgaat
    13621 atttgatagc gcccaatcag ctgaaacctt aaaaagtagc aaggatacaa cctttgctgt
    13681 cctgaaacga aaaataaaca gctaccaaaa tccggagagt cacaaaacaa agttatactg
    13741 tggagcggaa tcattctatt aagtatagca acaatgcttt ctgcaaaaag atttaaacaa
    13801 aacagatctc tctaacattt gaataatgtc tgtgaacgca tttttcaaat aaaaagaaat
    13861 atccagaaaa tgaccccaaa ataccagatt gaaatctgat atttggggtc gttcatactt
    13921 tatctttctt catatttatt ttaagggata tctgtttctt ttggaagatg gttcgggatc
    13981 tttttcactt tcaatacatc taaaaagaag gtaaagatcg gaatgccgac aatcaagccc
    14041 caaacgccaa agaaccgttc gctaacaagt aagaccacaa atgtataaaa aatcggcagt
    14101 tctgttttgc tggacatcaa cttcggattc agcacataag actcaattag atggacaatc
    14161 aaaatcgtaa tcaggatata aacaacatct cggatgcctc cttgggaata agctatgaaa
    14221 gatagaggaa tacaagaaat gataacacct gctactggga tcagacttaa aatgaaaatc
    14281 atgatcgcta aactcagcag ctgatgaaag ccaaatacag ccaaggcgat tgtagtgagc
    14341 aacgtattta aaagagcgac aacaaattga gcttctaata ccaaaccaaa tgtattgaca
    14401 aacttatcgg caaaatagta aatatcttga aagaaccaag aaaattcact ttttaaaaac
    14461 aatcttgaga atacaattgt ttttttcttt tcaatcataa aaaagaaact taagatgaat
    14521 gacatagcaa acgccactgc catttttcct atatcctgta aatagccaag cgcaatcgaa
    14581 gcgccatttt gaagctgttc aaaaaaatcg tttcgctcaa tataagtatg gatatattgt
    14641 aaaacaggat ctgcatcttt tggctgatgc tcgtaaaaat caataacgga ctggatcata
    14701 tcaaatgttt gatgaataag catcgggata tactttgtga atgccagata gataaggtaa
    14761 acgatcagtg tataaatcat gatagctaaa acacctgtag ggattcggac aaatcgctga
    14821 atgatttgaa caagatgaat catcaaataa gtaaagataa atgtgagcaa aatggttgta
    14881 atcatacttc taactaagaa aagaacaaaa acgacaaata ataaaacagt gagacggcgt
    14941 attttttcat tcgccaaaaa acgctgataa acggtcaaat cgacaacctc caaataacaa
    15001 aaaataaaca cgttattcat tatatgatgg aatatgaaaa taagaaagag aaagagcaaa
    15061 aagaaaaacc gctaaatgac gttatcttat gagttggttt tcctcataaa atcgttcatc
    15121 tagcagtttc agcccttttt ctggtcttga tgaaaattat ctagcatttt tcgggtcaga
    15181 tgttgcagtg tatccaattc ttcctgttca agtggaagat aagacttgat cttttgtgga
    15241 ataccttctg cttgtttttg caacgcagca ccttgaggag tcagcgtaac atttacgatt
    15301 ctttcatcac ccgtttcacg ctgacgatta atataatttt tttctgctaa cttttttagt
    15361 aagggagtca gcgtaccaga atccagacac aaatcatttc ctagctcttt cactgaagtc
    15421 tttttctttt cccataaaac taacatcaca agatactggg tataggtaag attcagcggc
    15481 ttgaggaggg aagtgtagtg tctaatgatt tccttagagg cggcatataa aggaaaacat
    15541 acttgattaa ctaaatatag atcttccatt tttccacctc cgctgtttta ctatagtgta
    15601 tcatagcgga tttacacaaa aaagtctatt cactaactgc tttcagagta acttctatat
    15661 ttccagctgt agcttttgaa tacggacaca ctttatgcgc tgcctctaat aattcttgcg
    15721 tttcttccag agaaagacct tcgatagatc cttcaatctc tacacctaag acaaagctcg
    15781 tttcactttc tgaataaagg gaaacttgtg cactgacagt agaagcccca gagatatttt
    15841 tttgctgttt gatcaattct aatgcactgt taaaacatgc actgaaacca gctgcaaaca
    15901 attgttcagg gttggttgca ttttcgacgc gtttaccagg agctgcaata ttcaattcga
    15961 atgtacgatc gggattatga acttctccag agcgtccgcc tgtgttgatc attttcgtag
    16021 aatacatttt tttcataaaa ttaccacctt taattatatt ttatacaatt gaattttaca
    16081 caatataatt gtggaaagca aagaaatgga ttggcataag ataaataaga gaaagcacat
    16141 gaaacagacg cgctttctcg aatagcaaac atatacaaaa aaatatcaga gacaaaaact
    16201 aatctcatca taaacattac atatatttct caaaaagttg ttttctttct tcaaaactta
    16261 cttcacgatg gacctgatga agcatccata aataaccaaa aggatctctg aacattgagt
    16321 tagtcacacc aaagtccatc atttctgtca tttcttgaat ctctacacag ccatttcgta
    16381 atgctttatt atgtgtgtcc tcgatatcag agacgatgat attgaaccag atcgtatttg
    16441 gatgttcagc agtaggagca gtcaaaccaa gagacgtgtt ttcatccagc atatggaatc
    16501 tcgtgccata caaggtaaaa atgacttcat tattgcctct agggtaatct gttgcctcaa
    16561 tcagttgtat ttcatcaaag attgtttgat acagttctag tgctttcaaa ctatcattta
    16621 atacaaaatc tatttccgtt cctttatgca taaagatctc ctctcctttt cagtcgaaca
    16681 gttactagat tcttttatta taccagttaa agaaaacgca ttcaaaaaaa tagcggattt
    16741 acttaccaac tcattcgatt ggatgataag taaatccgcg tcccattact tctgctacgc
    16801 tgctgacaat gacaaaggca cttggatcga tttcttctat caatggtttc attcgggaaa
    16861 attcatgatc agtcacaacg atcaataaaa cctcttttga ctttcgatta tacccgcctt
    16921 ttgcctctag cagggtaagg ccacgtccaa tctcagcact taagcgaagg cggatgtctt
    16981 ccaaataatg ttcactcatg accataacag atttctttcg attgatacct gtttcgatat
    17041 aagtcatgac aattgaagtg attgcaatag ataaaatagc ataaagaaac tcttctattc
    17101 caaaaacaaa cagattaaga gaaacaacga atgcgtctgt aaaaaataag ccaatcgaag
    17161 tattcaagtg gaaatatttt ttaaaaatga ggggagggat cgtcgtaccg ccgctagaag
    17221 agttgttttt atataaaatc gcaactccta aagcaaaaat cgcacttcca aaaatgacag
    17281 acaacaaccg atctgaagta atcattgttt ctggaactat tgcaatgatt aaaggaaaaa
    17341 acaagcttcc gaaaagtact ttaaaaaagg gttttttacc taaaaataga agagctagta
    17401 ccaacataac gatattcaac actaaaataa ctatagctcg gtcaaatcct aaaacagctt
    17461 ccagtaatat tcctagaccg ctgacacctc cagcagcaat atgatgaggc cctaaaaaca
    17521 tattgatagc gactcctaat atgaagaggg caaaaataat cttaatgtat gtccatataa
    17581 attgtctcgt ttctttcatt tatccacttc cttaattcat taataatact cttatcttat
    17641 tataacttac ttttcacctt aagttaactt taattaataa aaaaattagg ctagtctaaa
    17701 ttattatgtt tcattcttct agaatatact tctacgttaa aaactgttaa aaaactttta
    17761 ctttagaaaa ttggagaaat tgatcgctta agataaattc aggacactaa atagtacagg
    17821 aagtagatta aaacttttaa aagttttaag tctatctatt tggcaagttt aaaaaataaa
    17881 aattcggtat caaaaaactg ttaccgataa catttttgaa agcgttgtct tttgtttctc
    17941 tatcacttat agtgatgacg tcatattaaa acacaaggag gaaatcaatg gatacagctg
    18001 caatttatca tcgaccggaa agtgaatatg catttctata tacgaataca agatttcgta
    18061 ttcggcttcg tactaggaaa aatgatatca aaaaagtata tgtgctttgt ggagatccat
    18121 ataccataac aactgaaaaa tggtatcaaa aacaacgacc aatgaaaaaa tgtctaagta
    18181 ccaatgttca tgattattgg gaaattgaag tgacgagcga aacaaggcgc ttacagtatg
    18241 cgttccatgt tgttggggaa gataacacgg actgttttta cggtgatcaa ggaatttttc
    18301 cttatcgaga aaatgtgatt actgaaccaa atttttattt tcgaatacct tattttcatc
    18361 aaatcgatcg attcactatt ccagaatggg taaaagaaac agtatggtat caaatttttc
    18421 ccgaaagatt tgcaaacggg gacaaagcaa atgaccccga acacacttta ccttggggaa
    18481 gtaaagatcc agaccgagaa gacttcttcg ggggagattt gcaaggtgtg agggatcatt
    18541 tggattactt gacggacctt ggcgtcaatg gcatctattt ttgtcccata tttaaagcca
    18601 catccaatca taaatacgat acgattgatt attatgaggt ggatcccgct tttggcgata
    18661 aaaaactttt aaaaaacttg attgatgaag cacataaaag agggatacgt atcatgttcg
    18721 atgctgtatt caatcatatg ggtgtccatt caccacagtg gcaagacgtt ctcaaaaacg
    18781 gagaaaaatc gatctataaa gactggttcc acatccgttt tttcccagta gattcttatc
    18841 agatgactga cttaccagaa actgctgaaa atatcccata tgatactttt gcttttactc
    18901 cattcatgcc gaaactaaat acagcaaatc cagaagtgca aaaatatttg ctggatatcg
    18961 caacttattg gataaaagaa ttcgatattg atggatggcg tcttgatgtt gctaatgaag
    19021 tcgatcatca tttttggaaa aaattcagag aagcagttac agaaatcaaa ccagacatct
    19081 atatccttgg agagatttgg cattcctctc aagcttggct gcaaggggat gaattccatg
    19141 cagtgatgaa ttatgcattc acagattcga ttaaagatta ttttgcaaaa aagaaaatca
    19201 cagcttcaca aatggtcagt ggaatgaatc atcagcaaat gctttacaga gatcaggtga
    19261 acgaaggaac attcaactta ttagattctc atgatactgc caggatcttg accctttgcc
    19321 aaggtaacaa agaattgatg aagtctgtga tggcctttat gtttcttcaa aaagggtctc
    19381 cttgtatcta ttacgggaca gaaataggga tgactggtga agatgacccg gattgccgca
    19441 aatgtatgat atgggagaag gaggaacaag atctagagct attcggtttt ataaaagaac
    19501 ttgtttctct aaggaaacag ttgtctaaga ttatttctga aggttctact cagtggctaa
    19561 tagtatatga tcgtgaagat aagctctatt tcacacggga actagaggga cagatcatct
    19621 atgtttactt taatcagtca aaagaacctt gggtagtaga acaggaaaat gaggtgattc
    19681 ttagtcaaaa ttgtcagttg ttagaagacg ggaaagcaga gatacgacaa tacggatttt
    19741 tgatcatgtg ttgaaaactg ttaccggtaa caacaagaaa gcgtttgcaa atgaagattt
    19801 gtgcccatta taataagggt gtaacagcac gttgaataca caggaggaaa tgaagatgaa
    19861 aaaaagaagt gtgaaacagt tgggtttagg gttaatctct ttaggaatct taggcggatt
    19921 agcggcttgt ggcaatggta actcttcagc agaaggggaa gccgatgaag gaaaaacgtt
    19981 aacagtttcc gttgattctg gatataaaga ttatataaac gaaataaaaa acactttcga
    20041 aaaagaaaac gatgtgaaaa tcaagctagt agaaaaggac atgttcgatc agttggaatc
    20101 attagcgtta gatgggcctg ctggaaaggg acctgacgtt atgatggcag catatgaccg
    20161 gatcggtgcg ttaggacagc aaggacatct ggcggaagta aaactgggaa atgaagcagc
    20221 ttacgatgaa acagacaaag cccaagtgac ttatgatgga aaaatctacg gagaacctgc
    20281 agtaatcgag acccttgttt tgtactataa caaagattta gtcgatacag caccatcaac
    20341 gtttaaagat ttggagaatc tatccaaaga cagtcgtttt gcttttgagt cagaagcagg
    20401 aaaaaataca ggatttttag ctaaatggac tgacttttat tattcctatg gtttaattgc
    20461 aggttacggt ggctatgtat ttggtgatga tggcacaaat ccttcagata tcggtttgaa
    20521 taatgcaggt gctgtagaag gaatctctta tgcaacagat tggttcaaaa atgtttggcc
    20581 aaagggaatg caagacataa aaagtgcagg agacttcgcc agccagcaat tcatgtccaa
    20641 taaaactgca gcaatcattg acggtccatg gcaagcgcaa acatacaaag aaaacaatat
    20701 caattatggt gtagccaaaa ttcctactct aaataatgga cagccttatc aaccgtttgg
    20761 cggaggaaaa ggatgggtag tcagcaatta tgctaaaaac aaagacctct ctcaaaaatg
    20821 gcttgattat gtaacgaatc aggaaaatca agaaaaattc tttgaaatgg taaatgaaat
    20881 ccctgcaaac caacaagcta gggaaacagc aaaggctaaa aacgatgaat taacaacagc
    20941 tgtgattgaa caatatgaaa cagctcaagc gatgccaaac atcccagaaa tgggcgaagt
    21001 ttggacaggt gcagaaaact tgatgttcga tgcagcatca ggttcaaaaa caccaaaaga
    21061 atccgcagat gaagcagtaa aaacaatcag tgaagccata gaacaaaaat actgattaaa
    21121 atgataaccg tccattttta taaaaaatgg aacaggtgct tcagataaaa gtggcaagag
    21181 cgagatggaa aattatcttg ctcttgttgc cattatctta aaagcagttt gcggtttagc
    21241 aagtttagag ggggcattca gatgcagcaa gataaaacaa gcaatatcaa cgaaaaaaaa
    21301 atcacgcttt gttcacttat tccagggatg gggcagtttg taaatggcca agcttttaaa
    21361 ggtatcgttt ttttcgccat attcgtccta ttcattggtc agatgcttct gggcggattt
    21421 catgcattgg taggattggt tactttggga agtataccaa tggaagatca ttcattattt
    21481 attttgattg aaggcacttt gcaattcatc attacaatca ttttcttgat tttttacggt
    21541 ttgaatcttt tagacgctta tcgagtagcg aagatgcgtc aagagggcaa aaaaatcaat
    21601 cggacgatga aggaagtcat acataatata ggtgatgaag gttttcctta tctattgaca
    21661 cttcccgctt atcttctcat gatttttacg atcattttcc cagtcctagt tacattgttc
    21721 actgcattta ctaattatga cttcaatcat attccaccag ccagtttaat tgattgggta
    21781 ggggctaaaa acttttttag tatcttcttt ttaagctcat atcgtaatac tttttttgca
    21841 gtcttttcgt ggaccgtgat ttggacttta tgtgcaacaa ctttgcaaat cacccttggt
    21901 attctcacag cggttgttgc tcaccagaaa tttattaaat tcaaacgtat tttcggtatc
    21961 attttcttat taccatgggc ggtcccagct tttattacta tcatgagttt ttcgaatata
    22021 ttcaacgata gcgtaggtgc catcaatact caagtgattc ctttcataaa ccagcttcct
    22081 tttgtagata tcagtgcaat ctcttggaaa acggacccga actggacgaa agtagcaatt
    22141 atcttagtgc agggctggtt aggatttccc tatatctatg tgatggttac aggaatctta
    22201 caatcgattt cagaagactt atatgaagca gcaaaaatcg acggagcaaa tgcatggcag
    22261 cgcttttcaa acatcacgct tcctgctgtc ttcctagtgg cagcgccaac atttattaca
    22321 cagtatacgg ggaatttcaa taatttctcc atgatctatc tgtttaacaa tggtggtccc
    22381 ggaagcgtag gcggaggagc tggttctact gatattctta tttcctggat ctataaactt
    22441 acgactggaa cttctccgca gtattctatg gcttcagcaa tcacgttgat tatctccgtc
    22501 atcgttatct gtgtgtcatt gctggtattt aaaaagacaa atgcgttcaa tatgggggat
    22561 taacaatgaa aaaatttcat tcgagtgctc gattccaaaa acgactttct cactttttta
    22621 cttacttttt tcttttaata ctgtcagtca ttatcatcta tccgcttttg atcacagcaa
    22681 gtactgcctt caagtcagga aatattgcag cttttagttt agatctttca agtgactgga
    22741 ctttaggaaa ctttactcgg ctattcagtg aaacacttta cgggacttgg tataaaaata
    22801 cattgatcat ttctgtccta acaatgatcg tacaagtgac tgtagtaact ttggcgggct
    22861 atacttatag tcgctatcgt tttatcggcc gcaaatcaag tttgatgttc tttttagtga
    22921 ttcagatggt accgactatg gcagcattga ctgcctttta tgtcatggct ttcttattag
    22981 aagcgctcga taagtactgg ttcttgacaa tgatctatat aggcggtgga attccaatga
    23041 atacttggct gatgaaagga tactttgaca ctgtaccaat agatttagat gaatctgcta
    23101 aacttgatgg ggcagggcat ttcaggattt ttttccagat tgtattaccg cttgtcaaac
    23161 cgatgctcgc cgttcaagca ttatgggctt ttatgggacc ttttggggat ttcatgttag
    23221 ctaagttcct gcttcgaaca cctgaaaatc agactgttgc tgtcggctta caaacattta
    23281 tttctgatgt gacaaaccaa agagtctctc tttttgctgc tggggcaatt ttgattgcac
    23341 taccgatttg tctattattc ttctttttac aaaagaactt tgttaccggc ctgacatctg
    23401 gcggaacaaa aggataggag cagagtatca tgcaaacatt tccgttaaac tatttttccg
    23461 cattacgtac gccaactcaa gtgtttgcgg gacgcaaact attatcatgg cctaaatttt
    23521 tcttgatatt tgtattttta gtttccttga tggtcatgcc tgtgactctt ttttatgcca
    23581 atcagatcca agcgattcca ttagaacaat ttctatccgt tcattcgctg atcgatgaac
    23641 aaggaaccca aaaattttct gaacttgaat tatctgaaac tgggttacaa gcatcgcaac
    23701 aaacgatagc tgtgacccct gaaattttgg taggtgtgtc tttatctgag aaacaacaat
    23761 ccgatcatgg aacttttatt gattttgaga aggaacaatg ggtgatccaa caaaaggata
    23821 aatctggtat acgccgctat acgatgaatt atagcccatc tttccaacca gattctgtac
    23881 gtacgcccga agatttccaa cgatttttag aaagagaatt ttatgccagt aatcgtccaa
    23941 caatcatttt atcttatagt ttaagtcttg gtcttgtcct atttgtcatg acgagtctca
    24001 ttttattcgg ggcttccttt ttcttgtgga tgacaagaaa aagccaactt tcatccattc
    24061 atacattcaa agagagtgca aatttgatgc tgaatgttat gggaataggt tccatggcag
    24121 cagcagttgt agggtttatc cactttgact ttatcttgat gctaagtgtc caaacaacga
    24181 taactgtctt gctgctttta tgggtttttg tcaaaacaag attcaaagat aagcgtgtcg
    24241 aatgacaagt ttaagcgatt tatgcgacaa tgaatgtgaa aaaaatgaaa aataaagtag
    24301 tttttgaaaa atttctgaaa aaattaaact tcttagttga ttcttttctt ttttagtatt
    24361 aacgtaatag ggtagttttt ttaaggagga aaatcatgtt agagaaaact ttatacaatc
    24421 aattattttc acgttctttc tcgctccctg tcgaagtaaa ttattgggac ggtacaacga
    24481 aacaatacgg agatacggac actcctcccc aaatcaaaat caatatccat gaagaaatcc
    24541 caatgaaaga gattacaagt aacgcttctt tggcactagg agaagcctat atggatcatc
    24601 gaatcgagat cgagggaagt atccaagcat tgatcaacga tgcttatcag caagcaaaca
    24661 gctttttacg aggaaaagat tatctaaaat ggctgccaaa gaaagaaaaa catacgaaac
    24721 aaaaaaacaa agaagatatc catgcgcatt atgacttagg taacgacttt tataaacttt
    24781 ggctagatcc aactttgact tattcttgtg cttatttcaa tacacctgaa gatacgttgg
    24841 aacaagcaca aatcaataaa gtccatcata tcttagacaa actctttatc aaagaaggcg
    24901 aaacgttgct tgatatcggt tgtggctggg gaacattgat gttcactgct accaaagagt
    24961 ataatgtcaa ggcaactggg atcacactaa gtgaagaaca atacgatttg attaccaaaa
    25021 gaataaaaga agaacattta gaagataaat gccgtgtatt attaatggat taccgcgaac
    25081 taaaaggcga aacgtttgat catatcacaa gtgtaggtat gttcgaacat gtaggttctg
    25141 aaaatcttga aggttatttc aaagtggtaa aagatttatt gaaaccaaaa ggaacagctt
    25201 tgatccatgg aatcagccga caacaaggcg gtgcgacaaa tgcttggatc aataaatata
    25261 ttttccctgg cggttatgtc cctggtgtta ctgaattagt tgataatatt acaaaaaacg
    25321 atttgcaact gattgatttg gaaagcttac gtcgtgacta ccaattgaca ttagaacatt
    25381 ggacaaagaa ttttcatcaa gtccaagatc aagtcacgaa agaaatgggt gattccttct
    25441 atcgaatgtg ggatctatat ttacaagctt gtgcagcttc atttgaatca agtaatatcg
    25501 atgtgattca atatttgctt gttcaacctg gaaacaatga catcccaatg catcgtgcat
    25561 aattgaggca aaagtactgt ttaaagacta tttaaaaaga agctaagttt tatgatgctc
    25621 cagaagtgaa cttttttgtc taacttctag gattgtctct aaagcttagt ttctttttct
    25681 ttatattttc ataataaaag tttggttctt taatttttaa acatgacaga aaattttttc
    25741 ttcgttatac ttgtaataga atactatttt ataacaaagg ggatcgaatc aatgaaaaaa
    25801 actgttattt atactagttt atttgcagct ttgtttttag ctgcttgtca atcaaatacc
    25861 aatcaaggca catctgggaa tacgtcttcc agtagcgaac agcgctcttc acaggtatcg
    25921 gactcctcaa caaaagcaag cacatcttcg tctagccaga caaaaagttc tagtgaagca
    25981 agtactcagt cagatatcaa agtgtctgca gctcgtgcga tcgaattgtt ccaagataaa
    26041 tacccagata ctgcaattac tagtttggaa ttagatagtg attggggatc ttacttctac
    26101 aagatagaag gtgtcgatga tcaaaaagaa tacgaagcaa gaattgatgc tcaaaatgaa
    26161 aaaatggaga cagagaatcc agaaactcta gatcgagatg aacaaaatgg tcaaaagaaa
    26221 aaagaagatg gtctggatgt tgataaattg atcacgattg aggaagcagc aaaaatcgcc
    26281 gtcgacaaag taggaagcgg tacggcaaca gattgggatt tggataaaga tttaggtact
    26341 acttattggg aagtcaaagt aaaagacggc aatcaaagta catcagtcaa gatcaatagc
    26401 caaacaggcg aagtactgtc aactgaacaa gatgattaag aatttcttcg gaaaacaaga
    26461 gttgattttt cttttagtca tgatacacta gacaaaataa cttgtttgaa ggagcgattt
    26521 acttgagttt agaaacgacc tttgccaatc atatctttgc caatcctttg atgaatgcat
    26581 ctggtgtcca ctgcatgact acccaggaat tagatgaact ggctcattca gaagcaggag
    26641 catttatcac taagagctgt acgatcaatg aacgaaaagg aaatcccgaa ccacgctatt
    26701 ttgatgttcc tttagggagt atcaattcta tgggacttcc aaacttaggt ttttcttatt
    26761 atctagagta tgctcttgcg tatgaaaaag tgcaggaaaa ccaaaatcaa ccgttatttt
    26821 tttccattgc cgggatgagt gtccaggaaa acttggaaat gcttgagaaa atagaaaaaa
    26881 gtgggtttaa tgggatcact gaattaaatt tatcttgtcc caatgtgcct ggaaaaccac
    26941 aactagctta cgattttgag gccacttatg aaacactgaa agaagtattc agcatctttt
    27001 ctaagccgct aggaatcaaa ttgcctcctt attttgattt tgctcatttt gatcagatgg
    27061 ctgatatctt gaatcagttt ccattgacct atgtcaatgc tatcaacagt gtgggcaatg
    27121 gtttgtatat cgatacagaa caagaagcag tagtcatcaa accaaaagaa gggttcggcg
    27181 gcattggcgg agagtatatc aagccgactg ctttggcgaa tgttcgcgct ttttatacac
    27241 gtttgaaacc agaaatccaa atcattggta caggtgggat tcggacagga caagatgcat
    27301 ttgaacatct gctatgtggc gcaagcatgt tacagattgg tacagagctt cataaagaag
    27361 ggccggaaat tttttctaga atcataaaag aattaacgca gattatgtca gaaaaaggat
    27421 atacgtcaat tgacgaattt aaaggcaaat tacgcaccat ttcatagcaa agagacgaag
    27481 gtcatgattg atcttcgtct ttttttataa aaaacactcg tctgttcatt cctgtgcaag
    27541 cgtactcatt gtatgttaga cgaacttgtg ggaaaataac agaggcaaaa aggaggataa
    27601 tatgaatgat gcaacagaat tagcaaaaga gcttaaagaa aaagaattta gttttcaaga
    27661 actagttacg gatatacaga aaaaaataaa gaagcaaaat catgaattga atgcgtttgt
    27721 cgcgcttgaa ccattcgaga gtaattccca cgagctattg attccccagt cagaaaaagg
    27781 gccattggct ggtatcccat ttcctttaaa aatgctcggt caagaaaaaa agggatggct
    27841 agctacttca ggatctcgtt tatttgaaac acaccgagct tctcatacat ctaattatgt
    27901 gcggcaagca gaagcgatag gtctagttcc ttttggacaa accaatgcgc cagagtttgg
    27961 tttcaaaaat attacagacc cagtcatcta tggcccagca agaaaccctt ggaaccttga
    28021 atgtacaccg ggcggatcaa gtggaggagc tgctgctgca gtttcatcag gaatcgttcc
    28081 tttagctggt gctagtgatg gcggtggttc tattagaata cccgcttcgt tttgcggatt
    28141 gattgggctg aaaccttcgc gagggacgat gccagttggt ccatatgctt ggagaggatg
    28201 gcaaggagct gctattgatt tcggcttgac agtttctatg agagacacgg aggctttatt
    28261 ttatgggatg agaagtatcc attccggtgc gccatatcaa gtatcgccag ttgagtggca
    28321 aacacatcca agaaaaaaac ggttgaagat agctttttgt gttgattcac cgatccactc
    28381 acagattagt gaagaggcag tacttgctgt aaaaaaagct gtagatttcc ttggaaaaga
    28441 agggcatgat ttgacagaga ttccttaccc actagatggt cgtaaactga tcacgtctta
    28501 ttatcagatg aatggcgcag aaacagcagc aatgatccgc tcgattgaaa caggcatcca
    28561 gcgagctgtc agaaaagaag aacttgaacc catttcttgg actttgttcc aatatggtca
    28621 gaagctctct gccgctactt acatcgattc tctgcatgta tgggatgaag cagcaattgt
    28681 catggaaaac ctacatcaag aatacgatct attcctttca ccaacgactg catttaccgc
    28741 ccctaaaatc agcgaagatt tgcaaagtga tgcgataaga gcacagatgg aacacatcag
    28801 tgattgttct gaagtagaag gtttagacgt tgtttcttcc atgtttgagg agagcttgaa
    28861 gatcacacct tatacacagt tggctaatct gactggacaa ccagcaatca gcttgcctac
    28921 tcatttgaca aaagaaaaca tgcctctagg aatccaattt atggctgcca gaggaagaga
    28981 agatttgcta tttcaaatcg gctatctatt tgaagcaaat catcagttcc atttaccaaa
    29041 tccatggaaa tagcagaaac aaggagaaga agaatgaaga aaaaaagatt gtttgctcta
    29101 ataactagtg ccttttttat tttaagcgct tgcggtacag ctgccgctaa tcaggaagat
    29161 aacagctgga gtaatgtaga aaaaaagaaa gaattagtag tagcgacttc tggcacactg
    29221 tttcccgcat cttattataa tgatcaaaat gaattagttg gttatgatgt agatttggca
    29281 aaagaggtgg ctaaacggtt aaatgtcaaa atctccttta aagaatacaa cgtggatgga
    29341 caaatcactt ctgtttcaaa aagagaatca gattttgctg cgaacgattt tggtatcaca
    29401 aaagaaagag aaaaaaaatt ctccctttca gagactttca aatattcatt tgacagtatg
    29461 atcgtacgaa aaaaagatga ttcaggaatc cactcacttg aagatcttaa agggaaaaaa
    29521 gcagctggcg aacccaatac tagctatatg cgtttagcgg aaaaacacgg agctaaatta
    29581 gtcacatatg acaatgccac gaatgatcag tatttaagcg atgtagcaaa tggtcgaaca
    29641 gatgttattc taaatgatta ttatctgcag aaaatggccg tatctgcttt accagatatc
    29701 cctgtaaaaa tactggagaa cgtttatttc aatgaaaacg aaagtggttt tttattgaaa
    29761 gaaggaaatg atgctctgaa aaagaaaatc gatggcgtat taaaagagat gaaagaagat
    29821 gggacgacaa agaaaatatc tgaaaaatat tttcaaactg atgtttcagt caaaccgaaa
    29881 gaaacgatgg ctgagtcggt gagtgagtga tgtactttcc cctaattgat ttttccctca
    29941 tgtggacttc acttcctttc gtactgcaag gcttggtata cacattaggg attggcttcg
    30001 tgtcgtttct tttaggaaat ttggtagggt tgcttttgac agttttaggt cttttggatt
    30061 ggctgcctct gaatgtattt attcgttttt atttatcgtt ctttagaggc attcccgcac
    30121 tagtcctgct gtttctgtta tatttcgggt taccttatca attaagtgcc ttaacggctt
    30181 cagtcatctg ctttacgatt accagcagtg catttattgg tgaaatctat cgaggatcac
    30241 tagcaggcgt ttcttcaggt cagtgggacg ctggtttagc ttctggtttt tctttctttg
    30301 gggtattgaa atatatcgtt ttgccgcaag cttttcgaat ctcagtaccg gcactcagta
    30361 acgtagctat ggatctagtg aaaggtactt cgttagcagc aacaatcaca gtgccagaaa
    30421 tatttcaaaa agcaaagatc ataggcggtc ggacattcga ttatttttct ctctatattt
    30481 tagttgcact gatttattgg gtcatttgta tcgggatcga aaaagtgcaa cagtatttag
    30541 aaaaacgttc tatccatcag tcaatctgaa aaatagaaat ggtgctagcg tggctggcac
    30601 catttctatt ttttgtttct tgtatattct gcctagtatt ttaaaaccat ttcatgtaaa
    30661 atgtaaatcg aaaatatgtt cggaggtaga aaacatgaag accccgctaa ccatcgaaat
    30721 agaatcctcg ttataccaat attgcatcga gcaaggcggc ttggttgtag aagaagtcac
    30781 gatgcctgat gaccaaggaa ttgtagatac gcttagctgc ttgacaaaat ttgatggaag
    30841 ccgagaatgg cgatgctatg agctgaaagt gacaaaagca gattttcgct ctacagccaa
    30901 actgtcattt gttggacatt ataattattt tgttttacca agtaaactat atgaagaagt
    30961 aaaaactgaa atccctacag gaataggtgt tttagtgtat cgtccgtaca cggttgaaga
    31021 ggagatgcct gcctctggta catttctgat tgcgaaaaaa gcagcaaaga aagagcttgc
    31081 tgtaccggaa gaagctttga caaaccgctt catggcttct ttattcaggg aagtaagaaa
    31141 agcaaagcaa atggagcgag gcgtaaaata ttttccaaaa gatcaattgt acaaagaatt
    31201 gaaaagacgt tcagaaaatc aagatccatt ttctaacgaa cgatattatg aacggttttt
    31261 agaggaaata gctagtcagg caatcaatga gttgcaagaa gaagttatcg cgcttcagca
    31321 tgattatgaa tatttgaggc aacaacagca gatccgtcgg ttgcctacag agccattgga
    31381 gtgaaaaata tgtactatcc ttatttaaga ggaaaacaat ttgacctatt agcattaaaa
    31441 gaagcactgt cgcgaggatt gctctccaat aaaatccaac cagtgatcga accagtacgt
    31501 gattccgcta cgcttaaaaa tgtgatcgaa ttatttcaaa aaaagcacca tccaatcgct
    31561 gtgatccaaa atccccaagt aggacaattc aaattattcg atcagcatgt gcacagttgg
    31621 acagtcaaag aaaatagctc tgtcgtccct gcacagatct taacgccaga aaatctcagt
    31681 gaagtactgg attcacctcc agcgtttctt gttttcgatg gacagcacta cccaaaagat
    31741 acagaggtgt ggaaacagtt ggcaggagtt gattcgaaat ttttgatacc agatactagt
    31801 cgctttcgca tctggctgcc cgaaaacaaa attgtgatcc gtgactcttt tcaaacgaga
    31861 aagcatgttg aaagttatgc agataaaaca gatgactttt ttagtgatga ctatcttttt
    31921 ttccacgcag acggatatat tggattttct gatttcacga tcgaaggtag ccgttatttc
    31981 gataaagggt tccctagccg agcgcttgct atccatctaa cgtatattga tgcttacggc
    32041 aatatacgcg tgaaacattt tgtctctgac agtaacgact ctgctaaaga ccaagcattg
    32101 aagtttcttg aagcaggaga taaaatgaaa aaatggatca tgcgtcacca tcatcaactc
    32161 ttgattactt caggaatgat tgaattattg gctctttacc agcaacaaaa attccctgga
    32221 ctgggagtgt tgaaaaagtg gtcacttatg catcatttgg aacttattag tcacctgcta
    32281 gatcatccaa aagattggct taaatattat tcaaaagttc aggaactata tgaagtgatc
    32341 caatgattag ataatgtaaa tgaaaaagga atagaaaaga ggaaactgga tgtatattcg
    32401 gcaaacaagg aaagaagaag tagaagaagt ggtagaaatc attaatgccg cagcggattt
    32461 cattgcttcg caaggctctc ctcaatggca aaacgggcag aaaccaacaa aagaaacgat
    32521 tttgaacgat attgaaagaa aagaaagcta tgtattaata gtggaagatc aaattgctgg
    32581 aacagctgca ttagtctcag gcgtggatcc cgtttacaca aaaatagatg gtagttggaa
    32641 agaatcaact ggtccttatt tatcgattca tcgtgtcgct ttagcagaaa gtactcgagg
    32701 aaaaaaacta gcaaaaccgt tcttagaaca tttgttgacg attgcagcca gcaaaaatat
    32761 ccaagatatc cgtatcgata cttatccagc taatgaaccg atggaaaaga ccatctattc
    32821 tgctggattc acttatcaag ggatgattga atttcctttt gaacacggcg aaagaaaagc
    32881 atatcaaata atcatcaatt gactataaaa tcatctgagc aaagataaag acattaacac
    32941 tactgaaaaa aacaatcata tgatagccaa gaggttgtaa cagaagtggc cagcttcaaa
    33001 aaacaagaaa gaatttccga aaatgcttct caaatttttg tggaatttta gcgtatttta
    33061 cgaaatagct gctttctgaa actcccttca tcgagaggtc gtgacatagc ttttgtcacg
    33121 atctctcggc ttatcctacg agtattattc gatacattta tatcaataat ccttttttta
    33181 ttttatctgc agcttcttgg aacgctccat cgtttgacac gactaaaagt gaggggatag
    33241 ctttcaaacg tttcaactgt gctaaatctt ctacataaac cgccagtctg gctgaaatct
    33301 gttcagatga atctccacgt tttttcaggc gcgattgcaa tgtttcttta gagatcgtaa
    33361 taaagatagg acggactacc gtcccgaaat actcatataa atgccaaaaa ccatttgctg
    33421 tcaaaacggc gtaacaattt cctactgtca gtttcttttt aatttctgct ttactggaac
    33481 catatttatg ttgagcatat tggtcccact ctgcaaactc atttcccttg atcatctgat
    33541 tgaatgtatt gtcagaaaca aaataataat cctcttgatc tttttcccca ggtcttggtg
    33601 atcgattcgt gtaagtaatg atcttttgtt ccggctgaaa aatagcttct gcgagtgaag
    33661 tttttccaga accagaagga ccgataaata catagcaata attcattgtc atttctcctt
    33721 tgatgattga acaagtgaaa aagctttgga aaatatttcc aaagctttta aaagtaactt
    33781 tgcttttttg tattttatac cagcaagcca gtcacaatag cacttaaaaa gctgactaaa
    33841 gtcgctgtta gcaaaatttt caatccgtgt tttgcgacaa gatttccttt ttcttcattt
    33901 aatcccttca tcgcaccaga aatgatcccg atagaagaga agttggcaaa tgaaacgagg
    33961 aagacagata taattgctgt tgtacgctca gtaaaatgga aattaccatt tgctaattct
    34021 gtcatagcaa caaattcatt tgtaaccagt ttagtcgcca tgatactacc ggcatccact
    34081 gcttctttcc atgggattcc gctgatgaag gcaagagggg caaagatgta acctaggatc
    34141 tcttggaaag tgatgccgaa tatcccgtgg aagatagcat tgatcatggc aatcaaagca
    34201 acaaaaccga taagcatagc agcaaccgtg atcgccacat ggaaaccatc aagaatgtat
    34261 tctcccaaca tttggaaaaa tgtctgttct ttgttttctt caatgatcag ctcatcttct
    34321 ttttcttcta atacataggg atttacaatt gaagccagaa tataaccgcc aaataagttc
    34381 aaaacaaggg cagtgatcac atatttagaa tcgatcagtg ccatataaga tccgacgatc
    34441 gacatagaaa ctgtagacat agccgataca ctcatggtga acaaacgttt ctcagatagg
    34501 aagggtaatt ccttttttat ggaaataaaa acttccgatt gtcctaaaat agcagaagct
    34561 actccattat aagattccaa tttgcccatc ccgttgattt tacttaatcc tagaccaaca
    34621 gctttcataa ataatggaag aatcttgata tagcgtagaa taccgataat agcagaaata
    34681 aatacaattg gcatcaatac ggaaagaaag aaaggtgcac ttcctttatt tgctacaccg
    34741 gcaaaaacaa agtcaacacc ttgcccagca aaagcaagaa gatgatcaaa catttttgcc
    34801 aatacagaaa caaccgctgt accaaaagtt gtacgtaata atacgaaacc aagaacaagc
    34861 tgtaaaacga acatcacaat tagtggtttc aatttgattg cttttttgtt actgctgatc
    34921 aaaaaagcaa gccctaatgt gacaaataaa ccaataatac ctaataaata actcaaataa
    34981 tcactcctat tccaaattcc gttttatttt acctgttttg caaataaaat actaatcttt
    35041 agtgaaattt tcattacttt tttagagtga aacgcattca ttttccatta gaaaataaag
    35101 cgaacaaaat aaaaggttta aaaagtgtaa cgtcttagta aagtctataa aaaaacgaaa
    35161 ctatcgatta agctaatagt ttcgttttca acatttataa gtaaactttt tctattggta
    35221 atatagattt tcggaagggt agacaggtgc gcaggtaata tcgattccta gttttttcaa
    35281 tgtttgttca tcatttttat tgaccatcac agtagagtgg gcttgtgctc cctcaagttc
    35341 agctagttta tcataagcaa cttgagcgat tggattcgtt actgcactga ttgataaagc
    35401 gatcaagact tcattgatgc ttagtgcatc caaagaggaa tgaagtgtct ttgatttcaa
    35461 tccttgtatt gtttcaagaa ctaatggtga caataaagga atgtcatctg cgatatgggc
    35521 taaatgtttt actgcattta agataactgc cgctgacgca tccatcaatg aacttgtacg
    35581 cccggtaatg atgacttcat ctggtaattc gattgcaatc acagcagaag gatcttttgt
    35641 aggactttgc gcttgaatct tatctgcata gtcatgggca gggactacca cgtttcggtc
    35701 ttcaggacgt aaaccgactt cttccataat cagtttgatt cgattaactg cttcttcgtc
    35761 gatcaatcct tttttgaagt cgcattctgt ttggaaataa cgacggatga tttcttgttt
    35821 agaggcttct tggacaacgg tatcatccac gatcccaaat cctacacgat tcacacccat
    35881 gtcagtagga gattgataaa cagattcttt accagtaatt ttttcaataa tacgtttgat
    35941 tacaggaaat gtctcaacat cccgattata gttcacagct actttattgt aggcatcaaa
    36001 gtggaaggaa tcgatcatat tgacatcttt tagatcgact gtggctgctt cataagcaat
    36061 gttcagcgga tgtttcaacg gaacattcca tactgggaaa gtttcgaact tggagtaacc
    36121 agctgcatgt cctttttggc tttcatgata cagttggttc aagcaagtag cgagctttcc
    36181 acttcctggg ccaggagctg tcactacaac gattggttta gttgtttcaa tatactcatt
    36241 ttttccaaaa ccatcttctg agacgatttt ttctacgttg actggatagt cttcgatttc
    36301 tgagtgttta tagaccttga tgtttcgtct ttctagttta ttgataaaga ctttcgtggc
    36361 aggctgtcca ctatagcgag tgataacgac actgttgatt aataagccat aaccacgtaa
    36421 ttcatcgatt aaccgcaaga tatccatatc ataagtaatc ccataatcac cacggatctt
    36481 attacgttca atatctccag catagacgca aatcagtatt tcagcttgat ctttcaattt
    36541 ttgcagcaat ttgattttcg catcttcttc aaatcctgga agtacacgtt tcgcatgctt
    36601 gtcgtcaact aacttcccac caaattctaa atataatttg tcatagtggt tcactcgttc
    36661 caaaatatac gctgactgct cttcaatata tttttctgaa tcaaaaccaa tttttttcac
    36721 taggttccct ccttaagtac taaagcattt tttcattttt ttgaggattc gtcaactgga
    36781 agagcgaaat tcctcaaaaa aacaaagaaa atggtttaaa ccaacttgtc tagatagtta
    36841 ttcattggta tgatagtttt tgataaggaa ggtgctacat gaaaaaaaga cagaaaaaga
    36901 aaaacgcata taaacactat atccgttcga tttttaccgg ttatgaaaga atgcttgaag
    36961 atcccgaatt ggaacaattg acgtttactt atctaaacga agaaacgcag ctaactcgtg
    37021 atgagcatca gcgcattcat ttcacaacaa gagatctgcc tagtaaataa aaaataagat
    37081 aaaggtcatc ggattcgatt ctgtcctatc agatggaaag actagttgat cgaaaaaaag
    37141 gctgtaccaa attttggtgc agcctgtttt atggagcatt gcccgctctt ttttataaca
    37201 attttttaca gaaaatggta ctattgaagt attaataagt gaaaaacaga tgagtaagag
    37261 gaggcaagta gtatgaaaga gccagataca aatgcaaatt atgagccaga cgaactagag
    37321 gagacgaacg cggatcagga tacaggacaa gaatcgtctt ctttttacga tatcaaagaa
    37381 aaagcaagca tgaatctttc ccaattatta gaagacttac aggcttttga aaaagctgtc
    37441 cgcgaagaag atatccctga gatctaccgt ttatacaatg gccgattgaa tgaagaatta
    37501 aaaagaagct caaatgaaaa tcacgagatc gatcaattgc tgatgcgtaa gatccatgat
    37561 cgttttttac aggaatttcc ttttatggaa caagtagaaa acatctcgcc aacgatgagc
    37621 tattacaaaa tcggcactta ttaccatgat cggcccacgg tcggtattga tgcaagtctg
    37681 ccagaaattt ttgttttgcc taagatcgat gaagagtggg agaaatattc ccaaccggag
    37741 tcaacggact atgacaaaaa aatcaatgag ctagacgcaa aggtgatcac tgctcagaca
    37801 gaaattgaac gtttagatga acaaataaaa gaaatcaatc gacaaatgac tgatttgaac
    37861 gacaataaag gattcttgaa tcgtaaaaaa atcgaggaag aaattcaaga attagagaag
    37921 aagaagcaag tactatctaa tgaaaaatta ggctggcttc cttatattga gacgcctgaa
    37981 acaatccagc agcaaaaaga agcattgaag caagaagcaa gagcagacca gcttcgtgca
    38041 gccatcgtag aaaaagaaca aaggcaaatc agacgctatt tcggtagcaa agagggattc
    38101 ggtcaagcaa tccatgaatt cttgatgaat tatcttggca atgagaatcc taataatcaa
    38161 tctaatgaag gaggttccga gtatgaatga acacgatgaa gcagaatgga caaaaaatga
    38221 agaacaaaca gaagatcatg aagaaacgaa cacttcattg gaagaacaaa caagtaatcc
    38281 tctggatgac acagaagaaa tccctatgct agaggaaaca aaaatacatg aaaaagaaaa
    38341 agtaactccg acgaatacga atactgcaga aaacacccat gcttacgaaa taactgaaaa
    38401 tcccgggtat ttagaaggaa aagagcaaga tcatcaagat atcgtcagtt tgattgaaac
    38461 agcggaagca gaattagcgg atttacgtat gagaaaagat ttgatcgaat cagattttcc
    38521 acaattatta gaatcatatg atcgttttat attgaatgaa gaaccaatct ccacgatcgg
    38581 aaagacaagc ctgatcgaat acttcacgta tgaattactg aaaccgttga atgatattgg
    38641 tctggaacgg tcaaattcag cttatgacac atggaaaaca agacattttt cgatcaatta
    38701 tacgttgaat ggacaaaacg aattagtctt ttcctttgta ttaccgacca tcgatcaacg
    38761 ataccaagtg gaatcgatga gtctcctaaa cgtatcacca gagacaatgg aaatcaatgt
    38821 ccaagatgac cgggtgcttt ctttgatccg acactggtca gtggatcgag tattctctgc
    38881 agggcagatc acgatattca atcacaaatt gaatcaatta ttagcccatg caagaacact
    38941 tggttttacc gttaatcaga cattactaga caatacgaag ccacttcgtt tgaatcttca
    39001 gagcgaattt gaattgacga atgaagtatt ggatgatatt tttatcgtgg caatgaaaaa
    39061 tccatcctac gatatggaaa agatcaacga aactacttat caagtacgat tagataaagg
    39121 acagtcttta acgataacaa caaacgaaaa agatcaaaca gtcttgtcga tctcatctgg
    39181 agactaccca cgatctgtca ttgatttctt tatcaattac gaattcttgg tcccattaat
    39241 ggtgagaaag tcctgattgg ataagttgga ttaccagatg tcattcagat aattctgttc
    39301 caaaggactt gcggcagtta tccagaataa ttgtcacaag tcttttctgt atgtactaaa
    39361 tggacgtgaa taacttgctg atgaaggagg gatttcatta ggaatgtcca caaataaaat
    39421 agcacagctt agcttattgt ctgctgcttg tgtagcaggt aggatcgctt ttcaatttat
    39481 tccgaatttc cagccaatga ctgctatttt tttatttata gtactttact taagcttaaa
    39541 agatgcgtta attgtcatga gtctttctat tgcgatcagc agtttttatt ttggtgttgg
    39601 accatgggtc atcggccaat ggatcagcta tactgttgtt ctgagtttgt tttcaatcgt
    39661 ctgcttgaga aaaacagtgc aaaggaatct atggttaaag ggagtctgtt tttttctggc
    39721 gggcatggtt tacggaatag gtatgaccgt ttttgatacg ctgttatatc gtttgcctca
    39781 accttggatc tattaccttc aaggggtgtc gtttgatttg atgcacagta taggcaatgt
    39841 tgtgttcttt cttgtttttc tgccagtcgt caaacgtttt tacaatcatt caggaggaaa
    39901 aaatgaaaaa aataatttat agtttgcttg caatgagtgt cagtatactc attttgacaa
    39961 gttgcagtac aacctataca caatcggctt ccaaccaaaa ggaggaagta aaaacatcgc
    40021 aaaaagcaac aatcacgtta caagaaaatg gtcaaaactt ttcggaaaaa gaagtggtct
    40081 tcaaaaaagg cgatgattta ctgagtattt tgaaacgaaa ttttgaagtc aaagaagata
    40141 acggcttcat cacttcgctt gaagggcact cacaggatga gaaaaatcaa ctctattgga
    40201 tgtttactgt ggacgggaaa agtgctacta ctggtgccaa agagatcaaa ttgaatgatg
    40261 gacaatcggt cattttcaat ttgtctaaac tataagtttc ataaaaaact gttaaagggc
    40321 gaatattgcc ataattcagt gagttcagtt gatgaaagaa ggaaaataac atggaaaatt
    40381 ttaaaaaaag cggaatgttt tccgtaattg ctgctctagg ggctaatatt ctagttgcta
    40441 tcagcaaatt tgtcggctat gcaatcagtg gcagtgccgc catgctaaac gaaagcatcc
    40501 acagtatcgt tgattgcagc aatcagattt tgctgttatt cggtgataaa caagccaata
    40561 aaggacagag cgagttgcat caatttggtg aaggacgagc aaaatacttt ttcagtacaa
    40621 tcgtcgcaat gatgcttttc ttcggcggtg gggcacttgg ggtgatggaa gcttttgaaa
    40681 agttgacgca tccatcccat gaagtgggta atccgatcat tgttatagca atactgttat
    40741 ttggtttggt aatcgaagga agttcgttac gcgtggcaat gaaagaaatc aaagaattga
    40801 atactgaaaa actttccacg atgcgctttt tgcgcgaaag tcgacacagt gaaatactga
    40861 ttatttttac ggaagacttg tgtgctgtaa tcggtttggt cttggcttta gcaggaacaa
    40921 tattgactta tgcaaccggg attgctgcat ttgatgcgat cagcggattg ctgatcggtt
    40981 tcttgctgat gggagccgcc attttcctag caaaagaatt ttatagtctg atcatcggtg
    41041 aaagcgtgac agcaagcgat ttatcaaaaa tcaagttagc ttttgaacgt cctgagatca
    41101 gtcggctgat cgatataaaa acagttcatt taagtccaac ggagatttta gttgcagcaa
    41161 aagcagatat cgttggtaac aaagagaatg aagcttactc ggtcatcaat gatattgaaa
    41221 aaaatatgcg tcagtctctt cctgacaaga agatgtatat atacattgaa acagataaat
    41281 atgacccaaa ttattctcgt aaataaaacg tttattcatg aattgaagca aaaatgagaa
    41341 aaatataatc ttgtttttaa ataaaacggc tacaatttag cgaatttatg ttacaatgag
    41401 tccgctgttt atttgttgta attaaaggag atattttaat gaacaaaaag aaaagtgcgc
    41461 catggcttca agctttgcat gcagtgatgc cactttgtat aagctatata ccagtaggat
    41521 tagcttgcgg agtattgttg caaaaagttg gatttgatcc tctcttatca ggactgttat
    41581 cgattctggt cttttccggt ggcgcgcagt ttttagttgc atctatgctt acgacgcaag
    41641 catcatttgc aacgacatta ttgatggttt tctttttaga attacgctat acattattag
    41701 gagcaagtct tgccggtttt atgaaaaaag aaaagcggac gtttttggct gtcttttctc
    41761 aatcactgaa tgatgaaaac tatgcggtga actacttaaa gttttcaact gacccttcct
    41821 ggaataaaag aaaggcttta tatgtcaatt ggttctcaat gactgcatgg gccggtagca
    41881 atatgatcgg taattttttc ggctcggtga ttcgagtaga tgctgacctt gtccattttg
    41941 ctttgacggc catgttcatt ttcatgttta tcatgcagat gaaaagcgca ctactgatct
    42001 ttacaggttt attctcaggc gtattagggg tcgtattcat ggtattattc caaaatactt
    42061 tcggattgat tgcagcaaca gtcattgctt catttgccgg atttatgctg gagaaggcat
    42121 tcaaaaaaga aaaagctaag aaactaagag accgcggtaa agatgtcaat gagccgctct
    42181 tcaacttccc ggaacaggag gccaatcacc atgactaaac tatatttgct acttttagtt
    42241 gcttgtctgt tcatcgtggc atatatcccg cgcttgttcc cgatgcttta ttttactcat
    42301 cgaaaagtgc catcctggtt cagtgactgg atgaaatatg taccggtggc attatttgcg
    42361 gcgttagctt ttaaagatgt tttcattact catgaacatc tggatattgc ttggaatatc
    42421 aaaatagctg caatgattct agtagcaggc gtggcttaca aaacacgttc gatggcgttg
    42481 tcagttttga caggacttgc gtctgtcttt ttgctgtcta tgctttaaac tgttttattt
    42541 tattaaaaac agagattgcg acataagttg ttcaaactga tctatccgaa ctgcatttgc
    42601 aacagtcaat tctggatgca agtttattcg tagggataaa aaagattagt gttggcttat
    42661 gatgcaagct cttttttatt ttaggaatta gagagggatt tgtccttcta tgattttttg
    42721 ctataatagg gaagatgttt attttatgaa agaatagttg agggaattta aatgaataaa
    42781 aaattgatgc aaggaacatt ttggctaacc tttgctaatc ttctatgtaa agttttaggg
    42841 gtagtctatt tgattccctg gctaagtatg atggggaaca atcaagatgg tatgcttgct
    42901 acgacattgt ataatgttgg ctatcttcct tatggattgt tcctgatgct tggtacagtc
    42961 ggatttccaa atgcgattgc aaaaaaagta gctgtagcca caaaagaagg agataacgct
    43021 gcttgtcggc tgatttttag aagtacgatc aatatcatgt ttgtcatcgg tatcgcctct
    43081 gctgcactga tgtatttatt tgctccttta ctagccggaa tcagtccgat tgctaacgtt
    43141 aataatggga tactagctat cagaagttta tgcccatctt tgattgctat cccaattctt
    43201 agtgcaatga gaggatattt ccaaggaaaa aatgatctgc ggccttatgg aacttctttg
    43261 attatcgaac aggctgtgcg agtgatcgtt atcttggctg gtacttatta cttgcgcgta
    43321 ttgactgacg gaaccatatt agaagctgta ttgatcagta cagtcgcttc tttcttcggt
    43381 gggttagctg cgattatcca tatgtatatc gtcggacgca gaaaagactt cttcgaactt
    43441 aaagattttt tgatttccag ccgttatttc gaaagagaaa accgatctgc ctctgtctct
    43501 atcattcggg aaacactacc gtttattttt gtcggctcag tcattactat cgttcaaatg
    43561 atcgaccaag taacgatgaa accactgctt cactttttcc gtccagagat cgcagatcag
    43621 caactggaat tcttattcag ccgtgcttct gtcaatccaa ataaattgac attgatcctg
    43681 atctccatgg taggaacagt agctataagc agcttgccaa tattaagcac gatgaagaaa
    43741 aaagatcgga tacaaatcga aaaaacagta ggagatagtt tttcgattgc gttattgatt
    43801 cttcttcctt cattgactgg aatgtcttta ttagctggac cactatacac attgtttttt
    43861 ggctatgatc ctgaaagtgt cggatatttc caaatggctt tgctagcttc tttgtttttc
    43921 tctttattca cgatcctatc tacgatgctt caatctttga atcaccatcg ttttgcgatc
    43981 cgattaactg tagaagcaat tatcctgaaa gtcatcttcc aagtaatcgg attaggatta
    44041 gttggcggat acgggatgag cttatcaaat ggcttagcat tcggtattgt ctttgttcgc
    44101 ggctatcact ttatgtgcaa agaataccga atagcacctt tagcaaagat cagcaatttt
    44161 ttcttaaaaa ctttccgctc caccctgatt atgcttgcag tatgttttgc cgttttcttt
    44221 ttgctgaatc agcgattgtc aatggaatca aaaagctatg caatgattta ttgtgtggct
    44281 gtaggaagta ttggcggctt agtattttta ttttctcaat tcggaaaaaa tgggtttcga
    44341 atgttgaaaa atgttaaaca tcatagcaga agcaaagaat aggttaacta atcgtttttt
    44401 gctgtcactt gaaaaacggc aactcgtatg attacgcttg tcgtttttct attttccaat
    44461 tttagtttca tatctaatct tacttatgat atagttataa ggtctggaaa aattctttga
    44521 aacgaggaaa ttaaacacat gaaacttgca gtagttacag atagttcggc atatctgccg
    44581 gaacgtatca agaaccatcc cgacttattc gttattccaa tccctttgat tatggatggg
    44641 aaaatttata acgaaggaat cgatatcgaa gcggatgaat attatggact tttaaaaaac
    44701 agtaaagatt ttcctactac ttcacaacct gtcgtagggg aagttttggg tttatatgag
    44761 gaattgaaag agaaagggta tgacacgatt ttaagtatcc atctttcttc agggatttct
    44821 ggctttgtca acacattatt tgcgatgaaa gatgacatca gcggagtaac ggtcattcct
    44881 tatgactcta agatcactag tatgccgatg ggacacatgg tagaagctgc cttagactta
    44941 aatgatgaag gtcagtccct tgatgaaata cttgcacata tcgatcgaat ccgagataat
    45001 acctatgctt atctgattgt agatgatttg aacaatttag tacgaggagg acgtttgaca
    45061 aatggtgcag cgctgattgg cagcttatta aaaatcaaac cgatcctgac attttctgaa
    45121 gggaaaattg ttttattcga aaaaatccgt tcaagtaaaa aagcatttgc tcgagctgaa
    45181 gaaattattg gtagaagaaa taacgaaata caaccgccag tcaaacttta cgtgatacat
    45241 gcaaataatt tagaagtagc gattgcggag aaagagaaat tgcagaaaaa atatccaaat
    45301 gcagaaatcg aaattggtca tttcggacca gtcattggta cacatttagg tgaaaaagcc
    45361 atcggcattg ccatttcagc gcaataattc cttttattca aaaaacatac caaaaata
//
LOCUS       DAZULR010000024        42402 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.024, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000024 DAZULR010000000
VERSION     DAZULR010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 42402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42402
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.024"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(144..2297)
                     /locus_tag="ACG8ZV_001445"
     CDS             complement(144..2297)
                     /locus_tag="ACG8ZV_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan D,D-transpeptidase FtsI family
                     protein"
                     /protein_id="HFS4996794.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
     gene            complement(2591..3439)
                     /locus_tag="ACG8ZV_001446"
     CDS             complement(2591..3439)
                     /locus_tag="ACG8ZV_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFS4996795.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(3663..5603)
                     /gene="thrS"
                     /locus_tag="ACG8ZV_001447"
     CDS             complement(3663..5603)
                     /gene="thrS"
                     /locus_tag="ACG8ZV_001447"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HFS4996796.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(5940..6119)
                     /locus_tag="ACG8ZV_001448"
     CDS             complement(5940..6119)
                     /locus_tag="ACG8ZV_001448"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016862 - intramolecular oxidoreductase
                     activity, interconverting keto- and enol-groups [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxymuconate tautomerase"
                     /protein_id="HFS4996797.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(6166..7989)
                     /locus_tag="ACG8ZV_001449"
     CDS             complement(6166..7989)
                     /locus_tag="ACG8ZV_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFS4996798.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            8267..10546
                     /gene="helD"
                     /locus_tag="ACG8ZV_001450"
     CDS             8267..10546
                     /gene="helD"
                     /locus_tag="ACG8ZV_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase recycling motor HelD"
                     /protein_id="HFS4996799.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(10639..11286)
                     /locus_tag="ACG8ZV_001451"
     CDS             complement(10639..11286)
                     /locus_tag="ACG8ZV_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996800.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(11465..12184)
                     /locus_tag="ACG8ZV_001452"
     CDS             complement(11465..12184)
                     /locus_tag="ACG8ZV_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFS4996801.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(12315..13466)
                     /locus_tag="ACG8ZV_001453"
     CDS             complement(12315..13466)
                     /locus_tag="ACG8ZV_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HFS4996802.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(13683..14423)
                     /locus_tag="ACG8ZV_001454"
     CDS             complement(13683..14423)
                     /locus_tag="ACG8ZV_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFS4996803.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(14427..14750)
                     /gene="rsfS"
                     /locus_tag="ACG8ZV_001455"
     CDS             complement(14427..14750)
                     /gene="rsfS"
                     /locus_tag="ACG8ZV_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HFS4996804.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(14807..15400)
                     /gene="yqeK"
                     /locus_tag="ACG8ZV_001456"
     CDS             complement(14807..15400)
                     /gene="yqeK"
                     /locus_tag="ACG8ZV_001456"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HFS4996805.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(15384..16034)
                     /locus_tag="ACG8ZV_001457"
     CDS             complement(15384..16034)
                     /locus_tag="ACG8ZV_001457"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HFS4996806.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(16044..16355)
                     /gene="yhbY"
                     /locus_tag="ACG8ZV_001458"
     CDS             complement(16044..16355)
                     /gene="yhbY"
                     /locus_tag="ACG8ZV_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HFS4996807.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(16371..17480)
                     /gene="yqeH"
                     /locus_tag="ACG8ZV_001459"
     CDS             complement(16371..17480)
                     /gene="yqeH"
                     /locus_tag="ACG8ZV_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HFS4996808.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(17477..18004)
                     /locus_tag="ACG8ZV_001460"
     CDS             complement(17477..18004)
                     /locus_tag="ACG8ZV_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HFS4996809.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(18184..18969)
                     /locus_tag="ACG8ZV_001461"
     CDS             complement(18184..18969)
                     /locus_tag="ACG8ZV_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HFS4996810.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(18962..19831)
                     /gene="accD"
                     /locus_tag="ACG8ZV_001462"
     CDS             complement(18962..19831)
                     /gene="accD"
                     /locus_tag="ACG8ZV_001462"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HFS4996811.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(19832..21211)
                     /locus_tag="ACG8ZV_001463"
     CDS             complement(19832..21211)
                     /locus_tag="ACG8ZV_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HFS4996812.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(21219..21638)
                     /gene="fabZ"
                     /locus_tag="ACG8ZV_001464"
     CDS             complement(21219..21638)
                     /gene="fabZ"
                     /locus_tag="ACG8ZV_001464"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HFS4996813.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(21663..22139)
                     /gene="accB"
                     /locus_tag="ACG8ZV_001465"
     CDS             complement(21663..22139)
                     /gene="accB"
                     /locus_tag="ACG8ZV_001465"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HFS4996814.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVISEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(22142..23377)
                     /gene="fabF"
                     /locus_tag="ACG8ZV_001466"
     CDS             complement(22142..23377)
                     /gene="fabF"
                     /locus_tag="ACG8ZV_001466"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HFS4996815.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGTKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(23396..24133)
                     /gene="fabG"
                     /locus_tag="ACG8ZV_001467"
     CDS             complement(23396..24133)
                     /gene="fabG"
                     /locus_tag="ACG8ZV_001467"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HFS4996816.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(24145..25062)
                     /gene="fabD"
                     /locus_tag="ACG8ZV_001468"
     CDS             complement(24145..25062)
                     /gene="fabD"
                     /locus_tag="ACG8ZV_001468"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HFS4996817.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEATPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(25169..25393)
                     /locus_tag="ACG8ZV_001469"
     CDS             complement(25169..25393)
                     /locus_tag="ACG8ZV_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFS4996818.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(25446..26408)
                     /locus_tag="ACG8ZV_001470"
     CDS             complement(25446..26408)
                     /locus_tag="ACG8ZV_001470"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HFS4996819.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(26418..26858)
                     /locus_tag="ACG8ZV_001471"
     CDS             complement(26418..26858)
                     /locus_tag="ACG8ZV_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFS4996820.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            27164..28129
                     /locus_tag="ACG8ZV_001472"
     CDS             27164..28129
                     /locus_tag="ACG8ZV_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFS4996821.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(28186..28416)
                     /locus_tag="ACG8ZV_001473"
     CDS             complement(28186..28416)
                     /locus_tag="ACG8ZV_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HFS4996822.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(28538..29389)
                     /locus_tag="ACG8ZV_001474"
     CDS             complement(28538..29389)
                     /locus_tag="ACG8ZV_001474"
                     /EC_number="1.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFS4996823.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKL"
     gene            complement(29478..30701)
                     /locus_tag="ACG8ZV_001475"
     CDS             complement(29478..30701)
                     /locus_tag="ACG8ZV_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFS4996824.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(30718..31764)
                     /locus_tag="ACG8ZV_001476"
     CDS             complement(30718..31764)
                     /locus_tag="ACG8ZV_001476"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFS4996825.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(31928..33655)
                     /gene="ptsP"
                     /locus_tag="ACG8ZV_001477"
     CDS             complement(31928..33655)
                     /gene="ptsP"
                     /locus_tag="ACG8ZV_001477"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HFS4996826.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(33655..33921)
                     /locus_tag="ACG8ZV_001478"
     CDS             complement(33655..33921)
                     /locus_tag="ACG8ZV_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HFS4996827.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            34400..36634
                     /locus_tag="ACG8ZV_001479"
     CDS             34400..36634
                     /locus_tag="ACG8ZV_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFS4996828.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            36782..37102
                     /locus_tag="ACG8ZV_001480"
     CDS             36782..37102
                     /locus_tag="ACG8ZV_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HFS4996829.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(37307..37531)
                     /locus_tag="ACG8ZV_001481"
     CDS             complement(37307..37531)
                     /locus_tag="ACG8ZV_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HFS4996830.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(37729..39309)
                     /locus_tag="ACG8ZV_001482"
     CDS             complement(37729..39309)
                     /locus_tag="ACG8ZV_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HFS4996831.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(39710..41086)
                     /locus_tag="ACG8ZV_001483"
     CDS             complement(39710..41086)
                     /locus_tag="ACG8ZV_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HFS4996832.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(41214..42302)
                     /locus_tag="ACG8ZV_001484"
     CDS             complement(41214..42302)
                     /locus_tag="ACG8ZV_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFS4996833.1"
                     /translation="MFWSLELLIIAALIMISSEINFIFEPIGTFFSTLFAPVLIAGFL
                     YYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQISSLASNMPDF
                     IKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSLGSIVGTIASA
                     TVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTLANYISGQAIE
                     CLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLVTVFNDPVKAL
                     LCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLGIFLGVPFYAI
                     CKTIISYIIKIVKEDKQNENKKKIATTS"
BASE COUNT        11989 a         9124 c         7325 g        13964 t
ORIGIN      
        1 gtcacaacct tttttgccga gtaaacggtg ttcaaaagcc agtttctcgg tatgaagtca
       61 aatttaagca aaaatgtgag aagctatttt cacaaaattt ttcttcatac tcgaaactaa
      121 gcggcttttt cacgacctct tttttatttt gccatgaaca tatcataata cgcgtccatt
      181 atttctttag caatcgtcaa gtttatgtgg tcttgttcgt ctaataagtt cggcaagaca
      241 acactgatgg caatttccgg attgtctgtt ggtccgtatg ccacgatatt actattgact
      301 gtcgcaatat ctggatgacc ttccgcaacc gtttctgcag tccctgtttt tgcggaaagg
      361 tccattttcg cactggctaa tggtttggct gttgtgtaag gatcggtacc atggacaact
      421 tggtggaatc cttcacggag gatcgccata ttttctgcag aaatattgac cgtattttct
      481 actgttgtgc caatttcttt cttcacttca cccaagtttc cattttcgtc attgccatag
      541 atcgctttga ctaggtgcgg ctgtactcgt ttcccgccat tagcgactgt tgaagcatat
      601 tgagctaatt ggattggtgt atatgtgtca aactgtccaa atgccaaatc ggtaaagtta
      661 cctggagcat accattcttt gccattatcc gcattgaact tcttcatata atcaacagaa
      721 cgtgagatcc caggagattc attcggcaaa tcgatcccag tcgttgtacc aagaccaaac
      781 tctttgaaag agtctctcaa ttgctgataa gctttagctt cttcatctaa actaggtagt
      841 cccattccag gtgtatagtc tagtcctaac atctttaacg ccactttgat catatacgta
      901 ttagaagaca attccgatgc tttgactgca tcaagagcaa cttgtccgct tcgattaaag
      961 acagagcttt tttctgaagc accttgcaga cgaatcggct catcaatcaa aacttgattt
     1021 ccgctgatcg cgttacttgc ccagcctgct gtcaaagtac cagccttgac tacagaccct
     1081 ggatcaaagg cgctagtaat cgtgcctaaa gcattctcgg tgatttcttt ggaaccttgt
     1141 tcatgactga aaccagtcat tgctagcact tctcctgtct gaggattcat agccactgca
     1201 taagcaccag gcgaatactg tgctttgccg ttgttgatca atgtttgata attccttttc
     1261 aaaatttctt ctacttttga ttggaattct gcattcatag ataacattaa attagaacct
     1321 ttttccccag agaagatttc tttttgattc gaaacatttc cttcattatc aagggaaact
     1381 tcatattggg ttttggttcc ttgcaggaca tcttcatatt gtttttccaa ataactttgt
     1441 cctacacggt cattccgaga ataacctttt gctaggtatt tctctgcttc atctgctgga
     1501 agtccttgct tttcagtcgt cacactgcca agaatacttt tcagtgaact tgctgcatta
     1561 tattctcgtg tccagtctgt gccagtcgaa actcctggaa gttcagaagc gcgttctgcc
     1621 acaacagcta actcttgatc agtaacacca gagtttttga tatagacagt gtttaattca
     1681 tatgcactat tcatccgttt aaagatggta gcaattttta attgctcctc gtttaaatta
     1741 atctcatcag ctgtgacttt attgaccatc gcactatatt gttcgctgtt ccctaattgc
     1801 ttttcttttg ccgaaagtct ttttgtggct tctttcaaat gtttgggatc agccagccaa
     1861 aaatcttttt tatctctatc tgtcagattt tcatctaccg gaacatcgat cagcgagttc
     1921 agcttcgttg cgatttcaag caaatcttta gccgtaactt gtgttcctct cgtatatgtg
     1981 atggcctgat tcgctttatt cgtaactaaa gcttttcctg tggagtcgta gatcattccg
     2041 cgaggagtac tttcttggac cgtaatcgta gaagtagact tcactcgcgc ctccatctct
     2101 tcgccgttca cgatctgcaa ataacccaat ctagcaatca acgcaacaaa taacgtaaat
     2161 ataatgaaaa aaagaaaatt taagcgaaaa ggaacatggg accggcgaaa cgttttgttc
     2221 ttaggttctt gtgcaccttt tcttattttt tctaaccaag aagtatttaa tatttttttc
     2281 ataaaatctt tcatcatttc ctatccttcc gcctatttac attcatgctt cattgtaccc
     2341 aaaaacttct taataaaaaa gaaaaaatgg gcggagcaag aaattcttta cctaatttca
     2401 agataaaatc aactttttgt ttcacagcaa tcacttaaag ttacatatcc aactattttt
     2461 ttcattaaaa aataaactta tttttgaaaa ttatgttttc ttaagtcgtg aaacactttg
     2521 atggatcatt tatttgtgga aaactacgtt ttgttattct aaaaaactta tataaaaaat
     2581 agtaaggttt ttatttcgaa tccataaaat attcttggat tgcttctcgt gtttttttca
     2641 ctttttcgct aagcttttcg tttttagcca tatagaaata aaaaatgata tcgatcgtag
     2701 caaattgggc caaaagtgaa ttagttgccg cacttcgatt cgtgatttct tttggtctag
     2761 atgtttgtac gagtacatcg gctatcttgc taagcgggtt atttccaaat tgcgtcaacg
     2821 caatgatttc gatattcatg cttttcgcca gctcggctaa tgcgactaca tctgcacttc
     2881 tacctgagtt tgaaacaagc caaagcactt tctttttctc attgctgaca agttgcggga
     2941 gcaagacgtg gatatctttt tcaaaaatga ttggcttacc gacacgagac catttttgca
     3001 gaatatcttc tactactaaa gaagaggcgc caaccccata taaaaaaaca gtctctgccg
     3061 attccaaaca ctctacgact ttttggatcg tttcttcttc tagaatatct actgtttctt
     3121 ttatcgctac ttgtgcattg ttaccaagtt tgtttttgat agagtaaaag gactcatttg
     3181 cttctatatc actaaaacct tcatcgattc cagtctgtag ttctgttgaa atcgtgattt
     3241 tgaagtccgt cagactttga aaaccgattt ttttggaaaa acgtacaact gtcggcgcac
     3301 tcaacccgga agcttctgct aattcattag ctgtcattgt agggaccttc tcaatattac
     3361 cgataatgta gttggccaac tttttttctg ctgaagaata atcttccatc atactttcaa
     3421 tacgactaat tacgctcata agttcctcca cccttttaat gatagtctat gtaagtatac
     3481 catatcagac ccttattcac ggtcgtatac tggataaaaa acaaaaaaac aatccgccca
     3541 acagaatatc ttatcccatc aatcccacag attctattga gcatctgtgt ctttgaggaa
     3601 tacctgttat ctattgttcg gattgctttc tatctactac ttttttacag gaaatttacc
     3661 tattagtttt ctctgctgta atttttgact tctgcttcca tagcatcaat aaagatattc
     3721 aaatcttcta cagctgtttc tttacttcca taacgacgta cgttcactgt tgcatcttcc
     3781 aattccttgt ctccaacaac taattggtaa gggatctttt gtgtttgaga ggcacgtatc
     3841 ttatagccca ttttttcatt acgatcatca acttctacac gcaacccctt catttgcaaa
     3901 cgttctttga tttcataagc ataatcgcca tgtgcatcaa cagaaacagg gatgattgtt
     3961 gcttgtatag gtgccaacca tgttggaaaa gcgcctttgt atacttctgt taaataagcg
     4021 acaaaacgtt ccattgtaga aacaattccg cggtggataa ctactggacg atgcgtattt
     4081 tccccgtctt ctccaacata tgtcaaatca aagcgctctg gcaataagaa gtctaattgt
     4141 atagttgata atgtttcttc tgtaccaaga gctgttttga cttgaacatc tagttttggt
     4201 ccgtaaaagg ctgcctcgcc ttctgcttca aagtaatcta gttctaattc atccatagcg
     4261 gctttcagca ttgcttgggc tttttcccac attgcgtcat catcaaaata tttatctgta
     4321 ttgtttggat cgcgatagct caagcggaaa cgataatctg taatattgaa gtcagcatat
     4381 actgccacca tcaattcaag cgtacgttta aattcatctt tgatttgatc aggacgaaca
     4441 aatgtatgac catcattcaa cgtcatttct cgtacacgtt gtaaacctga caaagcacct
     4501 gatttttcat agcgatgcat cattcctaat tcagcgatac gaattggtaa ttcacgataa
     4561 gaatggatcg tgtttttgta gaccatcatg tgatgagggc agttcattgg gcgaagaaca
     4621 agcatttcgc catctcccat atccattggc gggaacatgt cttcttgata atgatcccag
     4681 tgtccagatg ttttgtacaa ctcaacatct cccattattg gtgtatatac atgttggtaa
     4741 cctagactaa cttctttgtc tacgatataa cgttcgatcg tgcgtcggat tgttgcccct
     4801 tttggaagcc agaatggcaa accagaacct acttctgggg aaaccatgaa caagtcaagt
     4861 tcttttccta gtttacgatg gtctctttct tttgcttctt cacggagacg gatatattct
     4921 ttcaaagctt tcttgtcaaa aaaggctgtc ccgtatacac gttgcatcat ttgattgttt
     4981 gagtttccac gccaataagc acctgccact gataataatt taaatacttg tatacggcca
     5041 gtggatggaa catgtggtcc acgacacaaa tcgatgaatt cgccttgttg ataagcagta
     5101 atcacttctt cttctggcaa ttcactaatc agttctactt tgtacggatc acttgcaaaa
     5161 atttctaatg cttcctgttt tgaaagaaca cggcgttcga tcggcagatt ttctttgacg
     5221 attttcatca tttctgcttc gattgccggc aaatcttctg cagttacttg gttttgtcca
     5281 ttatctgtat cgtagtaaaa ccctgaatcg atagctggtc caacgccaaa gtggatattt
     5341 ggatagaggc gacgcatggc ttgggccatc aaatgagctg ctgaatgacg gactaagcca
     5401 agtgcatctt catggtctgg tgtgatgatc tcaatacttg catcttcctc gattggacga
     5461 gtcaaatcaa cgagttttcc gttcacttta ccagctaaag ctttttttgc taagcttttt
     5521 gaaatgcttt cagcaattgc caatgttgtt gttccagact caaattcttt gactgcacca
     5581 tctggaaaag taatttttat cataatagtt tcctccttga aatgttttga ttgatcagat
     5641 catcaagctg aaaaacaaaa aaatcctagc atctcttgaa aagagatact aggacgaaaa
     5701 gttcgtggtt ccacctaatg ttcaaacgca aatgcgttcc tcaagcgttg taacggtccg
     5761 accgcccttg cttcaacaag ggtttcgaaa gtggtcatcc tttggttttc tcctggaaaa
     5821 gtttcagcct agcttttcct ctcttatcga agactctcaa attcagttgg ctttctcatc
     5881 aatcaattat gtgtttattt aaccactaat aaatagaaaa atcaagtggg aaactaaact
     5941 tattttttcc attccccatt tacaccgtat gttccttttt tcatctcatt gatgatgaca
     6001 tggatgtgtt cttttggtgc ctgcgtgttt ttatgaacag cttccgtgat atctttcatc
     6061 atattttcta attgttccgg actgcgacct tctactaatt cgacatgtac gaatggcata
     6121 atgctctctc ctctttctga tcgttctttt ttcaactcga ttctatcata ctatgtttgt
     6181 cttgggtact gaatcaggaa aaatggctgg atcttttttt gctctcaagg cactcaaaat
     6241 agagaccgta tccacgactt cttgcaaaac agctccgaat aatgcgggga ttagtcccgt
     6301 acttgcaatt aacatcaaaa aaatacaaat aaagatgcca atcagtacag actgtttcgc
     6361 tattctcatc gtatctcttg aaatcactac tgcttttgct acacgcaaga gatcatcttt
     6421 caagatgacc gcatctgcac tttcactagc agctgtagaa ccatgagccc ccattgcaat
     6481 accgatatct gcagcagcaa gtgctggtgc gtcattcacg ccgtctccta ccatcgcaac
     6541 aggtctttga tctttaggga tactttctaa aatggtcagt ttatcttgag gcaagctacg
     6601 ggcatgtaca gaatctaatt ggactttttc tgcaatcgtt tgagcaatgg cagatccatc
     6661 cccggtgatc atcatcaaat ttttcacatc aagttttctt agctccttga ttgtctttgc
     6721 tgcttctggg cgaatctgat ccgaaaatag gatcgttcct gcaaaagatc gatcaattgt
     6781 tacatagatt gctgtattgg acgtttctat ttcttcagct gaaacaaaag aggcacgtcc
     6841 aatctttact tcatgattat tgactactgc ttggattcct tgaccggtca cttctttcag
     6901 ttgactaaca ggatacagtt ggctgttttt cacgttgttc actaacgaac gagctaagat
     6961 atggctagat tcctgttctg cactagctgc atacagaagt agctcttctt tttttattcc
     7021 attgactggc tgaatcgcct ctacttccaa tatccctttg gtaagcgttc ctgttttatc
     7081 aaaagcaatc gtttttgtac gtgcgagctt ttcaatcgtt gttccagttt ttacaacgat
     7141 cccgttttta cttgaacggc tcattcctgc aactaaagca atgggcgcag ctagaatcag
     7201 tggacaaggt gatgccacta ccagtacctc agcaaatcgt aaagggtctt ttgagaacca
     7261 ccaagaaata ccaccgatca aataagcaat caacgtgaaa gggactgcat aacgatcagc
     7321 taaacggaca aatcgggcag gcttttcttt tgattcttcg actagtttaa taatcatttg
     7381 atactggctg tctgcggcac gtttttcagc gatcatttgg atcgatccgt ctccatttaa
     7441 agaccctgac ataatctgat ctccaggttt cttggtttcc gggcgggact cacctgtcaa
     7501 agaagattca tcgaccgaag attctccttt ggtcactcga ccatctgcgg gtacaagttc
     7561 gccaggcttg actagtaact ggtcatcaat atttatttca tcgattacta tatcctgcaa
     7621 ttttccttct ttgaatcgat gggcaattct tggggtgtta tctaacaaag actgcagttc
     7681 tttacccgct cgtttattcg cgtaatcctc tagactatct ccgcccgtaa gcatgatcaa
     7741 tatcatcaaa ctagcccagt attctttgac ggctaatgtt gcaaggattg cggtaatcgc
     7801 taatacatct acgccatatc ttcctgaacg taacgtcttg atcatttcca aaaacatcaa
     7861 gaaggcgaga atccctccag taaatgcgac aatcgcaaat gcaagggccg gctggtgaaa
     7921 aacaaattca cttaataaag ctatcccacc aataagcaaa gtaagtaaaa attttttgaa
     7981 atgtgtcatt gttttttctc ctcttttatg tgacttagag aggttagtaa taaatttcca
     8041 gctgcctctt tcatcttaag catagtcctt gactagcact ttttaaaaca ataggcctta
     8101 attgaaaaca actatcacta tcagcgtttc caaaattcat cagttctaca aacaaaaata
     8161 ttcagcaagg attacttttt cgattcatca gttaaaaagt accttttttc gaaaaactat
     8221 gctatacttt taattcgtta tttacggcgg aaggagcaaa catgcgatga atgagaaaca
     8281 actagaacaa acgcacgtgg atgaaacgat cgaactaatc cagatcgaac aaaatatgct
     8341 ggatacaaaa caacaagaat tgactcagga aatgaatcat tcgacaaaag acacagctaa
     8401 tcacaagatt cgagctggtt ccaatgaagc tttttatgaa tctgctgttg aatatcgcca
     8461 acatgagcag gaattgcttt tgaaatacca tactcttgaa gcacagcaaa aacgcctgca
     8521 aacgttgtct gtcatgaaag atagtcctta ttttgcccgt atcgacttta aagaagaccg
     8581 tgaaacagaa acattatatc taggtatcgc ttctttaaga gatctggcag aagaaacaat
     8641 cgttattgac tggcgcgcac caattgccaa tctttattat gaaggtgaga ttggtcccgc
     8701 attttatgaa actgaaacag atagaataga tgtcgatctg cagttgaaac gacaatttaa
     8761 aatccaagaa ggacgtattt tatctatggt agatacgtcg gaagtaatca atgatgactt
     8821 tttgctagag atattggatg aatcatcaag caaccatatg aaaaacatcg tctctacgat
     8881 acaaaaagca caaaatgcaa tcattcggga cacaacaagt aaagtaatgc tgattgaagg
     8941 aatcgccgga agtggaaaga catccgcttt gcttcaacgt attgcttttc tgttgtatca
     9001 taatcgcaag tggctcgagg ctgaaaacgt tcttctattt tcacccaacc atttgttttc
     9061 tgattacatc tcgactgtat tgccttcatt aggtgaaagc ggcgtgccta cacagacatt
     9121 caaaaattat ttggtgcagc tgctgccaga gttttcttta ctagatgaac agcaacaaga
     9181 aagtggtttt ttgctagggg aaaaagatcc gatacaagtg atgaaaagcg gattgacctt
     9241 agtcgatcag attgatcgct atatccaagg catcacaaac tacggtccct tgttccgtga
     9301 tatgaaaata aatggccgta cgatcctatc aaaggaatcg attcgccaat ggtataaaga
     9361 aacaaatgaa caattacctt tacatcatag actttctcta ttacaaacga agctcctgaa
     9421 aaaattaggc ggtctgcaaa aagacgaaac acgtcagcaa tgggtcaaag atctggcgga
     9481 agaacagctc caagaactat acgcaacaga tccaaatctt gaatatacag aacaaaagga
     9541 gcgttcatta cgtaaaaaac tggccaacca aatcgtacgt aaaagattcc gtcgaatcca
     9601 tcgagggatc atgaattatc aatttgtcaa tataacgaaa caatatctcc actttctaca
     9661 aactgtgcca ctttctcttc taacacgaca taaaatcagc gagaccaggt ggcaggaaca
     9721 tttgacaact gttcgtacac acttgcgtca aagagaattg cgtcaagagg atgctgtact
     9781 attcttttta ctgatgcgcc gaacatatcc agtgacggtt acacacaaag ctcgctatat
     9841 ctttattgat gaaatgcagg atttcgcacc atcacaagtg gcattgctgc aagccttgtt
     9901 cccaaaagca aatttgactt tctgtggaga tctaaatcaa aatgtctttg gaaatgaaac
     9961 gatcgttgga tcattggaag accttttcgt ggaccgtgaa gtcactcgtt tccaattaac
    10021 gacaagctat cgctccacaa aagaaatcac tgattttgct aatcatttta ttgtgaaaga
    10081 acatcaagta gaaacaacag caagaaaagg agaccttcct ttgctcatcc aaggaacaac
    10141 agatgatatc aaattgaatt ggttagcaga taccattcga acgactcagg gaaaagcccg
    10201 gtattggcgt acagcaatca tagctaaaac acaagaagaa tgcgaagctc tttatgctca
    10261 actgccagac gagttgaaac aacaagtcca gctgatttta aatgagagtg actttatgaa
    10321 gcgttccatt attttacttc cagccttttt agcaaaaggt ctggagtttg accgagtttt
    10381 cttgtgggat gtagatgcag aacatttttc ttctcagcaa gacaaattga tcctttacac
    10441 catgtgtaca cgtgcgatgc atgaattgac cctttttacc tccaataatg aaagtccttt
    10501 gttaaacaat atggatattt catcttatga gaaaaaagta ctgtaagtaa aaagacaact
    10561 gctatcatta atgttagcag ttgtcttttt atttacaata ataattgcag aaaaagtaat
    10621 tcaatcattt aaggtcattt attctatata taaatccaaa tctgtttcag gatattttaa
    10681 tttgacaagc gaaataatca ttttcagttc ttccatgttt tctggatatt ctgggtcaaa
    10741 taccttgcta tgacggccaa tcccgccatt gtcgatcaat cggtaaattc gattccattc
    10801 aatgaattgg tcaattgatt ggaaattgct gattggatag ccgccacaat ccaaaatctc
    10861 tgatacacga aatgctaggt atgcactatc gatcacttta ttttttttcg tgtctatctt
    10921 ctcatttctt tcgataagaa ttttttcagg acgatgtttc aagctccact ctaatagtag
    10981 aaagaaagcc tccatccgat actcttcttc aaataaccga aaggctgaat cagaacgacg
    11041 aaaaagcagc ggaatcagat aattttgtct ataaatcagc attggtgcgc ggtccaccat
    11101 acactctaaa taacggttca gataccctgt accgacatag tttcctaatc gatagccttc
    11161 aacgccgaat cttgcgtatt tttgcgctaa ttttgaacaa tcagttacgt tcacagctaa
    11221 ctcttctact ttgcggtaac cgcttaagat acgttcaaaa ggttctaaag tgatttttgc
    11281 ttccatattc ttccccgtcc atcttccaca tacttcatat catttcacat gatacttatg
    11341 ctctcatcat accacaggtt gaattagaaa agaaaataaa tcacacaaaa aagcaagaca
    11401 atctgttagt gagattgtct tgcttttcga aaaagactga atacttttcg ttaaaactgg
    11461 ttgcttagtc ttctaatgcc acattatgga acacatgctg tacatcttct agatcttcca
    11521 gtgcatcaat cattttttca aatgtttctt gatcttctgg agatagtgtt acctcgtttt
    11581 gagggatcat ttggatctca gcgattgaaa aatcagtgat tcctttttct tttaatgctt
    11641 cttgtatact atggaaatcc gctacttcac cgtaaacgat gatttgtcct tcttcttcca
    11701 ttacatcgcg aacatcgatg tctttttcca ttaggtattc aaggatctcg tcagcgtctt
    11761 ctcctgcaaa agcaaagatt gctgtattgt caaacatgta agaaaccgct ccggaaacac
    11821 ccatgttccc gccatttttc ccaaatgctg cccgtacgtc tgctgctgtt cgattcacat
    11881 tgttcgtcaa tgtatcaaca atcaccattg agccgcttgg tccaaatcct tcatagcgca
    11941 attcagagta tgtttcatct cctgcacctt ttgctttttc gattgctcgg tcaataatat
    12001 gttttggtac attataagtt ttagcgcgat caatgacgaa acgtagtttt tggtttgcat
    12061 gcggatcagg atcacctgat tttgctgccg cgtagatttc aatcccaaat tttgcataaa
    12121 tccggctatt attagcatct ttagcagttt tctttgctac gatatttgcc catttacgtc
    12181 ccatattttc acttcgcttt ctgatttgat agtttcataa cgcaaaaacg tcctgttcca
    12241 ttatacttgt gaatcacgat tctgtgaagc tttttttctt tcttccttca ttcttctcat
    12301 ttttagtcaa ttatctatac tcggattggg atttgcccga aattctgttc cggaatattg
    12361 cctcccaatt gatagatttg atcacttcta actaacagtt ccgcttcttg tgcctctttt
    12421 tttccgattc gggaataaat agaaatctct tttttttctt ttaagaatct tcttccagca
    12481 tcggtaaatc caagtagtcg aagataattt ttattttgtt ggacaggaat ctcttgcttt
    12541 ttgatattca gcaagacata acaagataat cgttggatcc gtgtccatgt atatcttttt
    12601 gtttttacct ttgacacaaa atcctcaaaa ctatcagcag ttgcagctgc tgttttcatg
    12661 cgcgattcta ttccttcggt catctgatag atatctgtca gttccagcaa agtagaagat
    12721 aacaaccgat aacgcaaata cggccaataa gattcccaag tctgcagcga acaagttgaa
    12781 agatcttctt ctgtctgagg cggcacaagt ccagctattc tttttccttc ttctaacgca
    12841 tggcgaatgg ctgttgcact ggctatcctc tgatctgtga tgattttttc atgatagcct
    12901 gcacttttac gtcggatcgg atgtaattcc atagggtgga catacttggc attttccttt
    12961 gcataactta atcccaagat atgatttggc gaagaaaaat caagcgtaat atcgggatac
    13021 agactgcgaa aaacctcagt cattttttgc ggataactat acgtttgatc agacagttct
    13081 tgaaatgcct cttctatcct atcttgattc tcttggacaa agcgtccgaa actgctgtaa
    13141 tcaaacgaag tctcttcttc tgttccaaaa cacaaactgt cacagtccag tgtttgcaag
    13201 atttttactg cacctttagc aaaatagtca gctgactgaa ccgcccattc gacgggaagc
    13261 tccactacta aatccacacc attttgtaaa gcttcattcg cgcgatgcca tttatcgatg
    13321 atagccggtt cgcctctttg caaaaaattc ccgctcatta cagcaatgac gacctctgct
    13381 cctgttattt ttcgtgccat ttccacatga tagcgatgtc cattgtgaaa aggattgtac
    13441 tctacgataa tcccgcagct tttcatgcgc atcctccttc atagttatcg ataaaaaaga
    13501 aatagagaca agtaaaaaaa ggcaaaaatc ggaaaaaata cccgaactat ataaactatt
    13561 ctcgcaaaca caatacttct gcgacgaaaa gctgcactgc aagagcaatg cctatatcgt
    13621 tcggatatat aatttatgtt gaagatttat tcttttcttg ttaactcgag caggcaaaac
    13681 cgctagtctt tgtatgctac aaagaaccag cgctttgatt tctctgatgc tgcttcgtct
    13741 gtaaaatcag aaaatgcttc gactttcgaa aagccgctgt tttccagcat tcttaaataa
    13801 ctttccaatg gataggtacg ctcttgatgt agttcatctt cacgaataaa tcgaccagac
    13861 ccttcttgtt cttcaacgaa aaaggtaaga aaatgttcga tgctgtgttt ctcgcttcct
    13921 ggataactat cccacaaaaa agcaaaatta tccccttgat aatgatagct atattctgga
    13981 aaaacctcat ctacttgata ggtggagtgt acgtcaaata aaaatcggcc attttcttct
    14041 aacgcttgat agacttcatc aaacacttgc tgtacctctt gtctattttt catatagcac
    14101 agcgaatcag aaaaacaggt aattgcctga tattgtccga tttctgataa atcgagcata
    14161 ttgccttcca caaattggat cgatgcgtct tcttcatatg ctcgctggct ggcaatcatc
    14221 aacatctctt ctgaaaggtc taaccctgtc actttatatc catcttttgc aaaggcaacc
    14281 gctaatgctc cagtaccgca tgccagttcc aaaatatttt ttgtgtcttc ttgtaaatga
    14341 cgtttcgaaa aagctaacca ttgctgataa agtgtttcgt ccatcacttc atcgtaaatg
    14401 aaagcaaatg tttcataagc catatgttaa tccaaccatt cactaagatc gactagcgga
    14461 gcatctgacc atagtttttc cagattatag aaatttcgtt ctggcgcatg gaaaacatgt
    14521 acgatcacat ctccaagatc gatcaatacc cattttccgc cttcttttcc ttcaatacgt
    14581 tttacttcat atttgttttc ttcttcttta tcaatgattt cttctgtaat tgcgttgatt
    14641 tgacgttcgc tatttgctga acagatcatg aaataatctg ccaacaagga aacatttcga
    14701 acgtctaaag cgataatgtc ttctgcccgt tttgaatctg ctgcttcaat cgcaattttt
    14761 aattgttctt tactatctat gatgatttcc tcctaatatg agcagcttat ttttttgcta
    14821 cccagtaatt atatgtttcg attgtttttg gataaatctg ttgttcttgc gcaagcaaat
    14881 gggccaatgt atgttttgtt tcaaatgcta cagcttcgtc tagatcagcc catgcaatgg
    14941 ctcgtgcatc ttgtacccca ggaaaatctc gacctggttc aatatagtct gctacataaa
    15001 tgattttgtc aaggagactc atcttagcag ccccagtcgt atgcacccgg attgcatgaa
    15061 gaatctctgc atcggtgatt cctaattccc gctctacaaa cgaagcgcca acaagaccat
    15121 gccagattgc attattataa ttcaataact ccggatcaaa accgtctctt acgattacca
    15181 ttttgaactc ctcatctggt cgttcttttg cataatcatg tgtcaatgca gcaatactag
    15241 ctttttcagg agaagcaccg tattttttgg caagagccac ggctgtttct tctactccaa
    15301 gcacatgctt gaagcgttgt tcgctcattc tcatctgtat tttttgcatc aggttttctc
    15361 tagaataagc agtatattca ttactatagt ccatattcat acaacccttc attttgaata
    15421 taatcaatta ctttatctgg aacaaggtag cggatagaac agccttcttt gatcttttga
    15481 cgtattttcg tggaactgat gtcgatctca ggtacatcta cccaaattac aggatatgga
    15541 gtatccgttg tgtatcctgg tcgacgtata cccacaaagt tgaccataga agtcagctca
    15601 tcgattttat accattttgg caaatattct accatatccc caccgataat aaagtaataa
    15661 tctgtatccg gattgttttg cgtcaattcc ttcatagtat cataggtgta acttttccca
    15721 ccacgagcta attcaatcgt ttcaatctgc aaaaaaggat tgtcttccac cgctaattcc
    15781 aacatgttga gtcgatgttt tgcatcaatc gtctgtttct catcaacatg aggtggctga
    15841 taagaaggca tcaaaaatac gcggtcaaga cctaaattcc ggccagcttg ttcagccatc
    15901 actaaatgtg caaggtgaac gggattgaat gttccgccca agatccctac ttgctttttc
    15961 ttctctaaga attgaggcat ttcttcagga aataattgtg aacgaacaaa tgtcttagct
    16021 tgcgtattca tcatggtcac tccttatatt gcttttactt cttttgatag cctttgatac
    16081 ttttcttttg tggaaggttt gtataataca ataacacgtc caatgatttg gacgatttcg
    16141 caatctattt ctttttctaa tacttgagct gcttcttctg caatctcatc tgtattttga
    16201 agtaacgata ctttgatcag ttctcttttt tctaaagctt cttcaatttg aacgatcatt
    16261 gctgaattga tcccaccttt tccgatttga aaaatcggct gaagatgatg cgctttgcta
    16321 cgtaaaaaac gcttttgttt tcctcttaaa ctcataattt tccttcttcc ttaaatcaat
    16381 gctttgcgtt tcaatacatc tacacccttt ggcgcccagc ccgcaattac tactggcgct
    16441 gttacagtga tccagcctag accggcaaaa acgatgtctg ttttttcttt cacagaaaac
    16501 tcaaaacgaa caagctccgg aaatgcctcg acttcatcag gacgaggagg ctgtaataat
    16561 ccacctacat gtttttgata aaattcgtct gctttttcca gtttcgttcg atgaatattt
    16621 acatcatttg acacataagc aataaatgaa gcacgattgc cgctgataaa atcaaatctt
    16681 gcaagtccgc ccaagaaaag tgtttgccct tcattcagct gataaacttt aggtttgatt
    16741 tcttttaacg gtgcaatgat ccgcaaatct tttttaccta agtagtgcgc catttgatgg
    16801 cgatggataa ttcccggtgt atcaatcaaa aaatgcccgt catctaaagg aatctcgatt
    16861 ttatccaagg tcgttcctgg aaactgcgaa gttgtgatta catcttgtac tcccgctgta
    16921 tttttgatga tttgattgat aagcgtcgat tttccgacat ttgttactcc gacgatatag
    16981 acatcccgtc catcgcggta ttcttcgatt ttttctaata gttccgtcat ctcatgagat
    17041 ttcttagcac tagttaataa tacatctact ggacgaattc ctgcttcgta agcacgttcc
    17101 ttcatccatt gtgttaattt agtttttttc aatgatttag gtaatatatc cactttgttc
    17161 ccaactaaaa gtactggatt gtcaccgaca aaacggtgta gtcctgggat tagtgaacca
    17221 ttgaagtcaa aaatatccac cacattgacg atcaatgcat ctttttgccc taattcattc
    17281 agtaagcgca aaaagtcgtc atccgtcaat gagacatctt gggtctcatt ataatggcgt
    17341 aatctgaaac aacgctgaca atagacttcc ccggaagcta aacctttttc caaagccgtt
    17401 tgcggcgtgt atcctaattc accgggtttg tttgtttgta taacggcacc acagccgata
    17461 cattgtaatt cttctgtcat tcgattccac ctcgccagcc catatcaggg tgttttgcta
    17521 atagataggc cataattctt ttttcccaaa aacgattaaa ttgtgtcttc caactatctg
    17581 ttgcgataat gggttttaca aggatgctac gtatccctgc acgattggct ccacgtatat
    17641 cagtcataat ctgatcgcct accattacta tctcatcatc tgctaaatcc aattgtttct
    17701 ttgctatgtt gatccctctt gctaaaggtt tcattgctcg tgcaacatac aaaagatcaa
    17761 atttttcaat cgctcgcgcg acacgttttg aattattgtt tgaaacaaca acaacaggga
    17821 ttcctgcatt tttcatttct aaaatccaag taagcaactc ttctgttcca tctggattat
    17881 tccatgcaat caacgtattg tctaaatcgg tcaatactgc tttgatgcct agattcttta
    17941 attgggcagg tgtaatctga tagatggctt ctaccatcca tgttggtttg taatttgaaa
    18001 acatgctgtc tcctcatctg caaaaaatga aggagcacat aaagtactcc tcaaccccgt
    18061 attatactgc atatcagcaa aaaaaactac ctctatactc gttcgtcttt cagaaaaagc
    18121 atttctttac aaaatgacca aaaataaaga ttgatcacag aaaaatttag aaacaaaaaa
    18181 caactaatat tggcggaacc tcttgtatcg tttttccagt aatttatgct gatctaatcg
    18241 aacaagttcc gtcaatcttt caatcaacgc ttttttcata atgtgtgcga ctttatatcg
    18301 tggcaactgc tcgccgttga acgtttcagg aataactcga tcaacgattc ctaactcgcg
    18361 tagttctggc gcagtaattt tcatcaactc agctgcttct gcggcgcgac taccgtcttt
    18421 ccacaaaatc gacgcaaatc cttctggaga aagcacagca taaatcgttt cttccagcat
    18481 ccagacttca tccgctaaac ctagagcaag ggcaccgcca cttccacctt caccaatgat
    18541 gatggcgatg atcggtacct ttaaatcaga catttcgagc agatttctgg caatagcctc
    18601 tccttcgccg cgctcttctg ctcctacacc gcaatatgca cctgctgtat tgatcaaggt
    18661 aatcaccggt ctattgaact tttccgcttg tttcatcagt cgtaaagctt ttcgatagcc
    18721 ttcaggatgg ggagaaccaa aatttctgcg gatattttcc tgcagatccc gtcctttttg
    18781 aataccgatc actgttaccg gtttgccatc taatcgagcg attccaccaa caatcgcttc
    18841 gtcatctgca aataaacgat caccatggca ttcctcgaaa gaatcgaaga tctcttcaaa
    18901 aaaatccaag cttgtccatc gttctttagc tcttgctaac tgaacgacat catgtgctgt
    18961 cttatccacg atctatccat cctttctgtg tatgcaattc aagaagcgta tggattttct
    19021 gtttcaattc catgcgggga acaatctgat cgacaaaacc atgagataat aagaattcag
    19081 ccttttggaa atcttctgga agttcctgct tgatcgtctg ttcgatgacg cgtcttccag
    19141 caaaaccgat caagctttgg ggttctgcta gaataatatc gccttccatt gcaaaactgg
    19201 cagttactcc tccggtcgtc gggtccgtta aaacagttag ataaaaaaga ccttcattgc
    19261 tatgccgttt gacagcagca gagatttttg ccatctgcat tagagaaaag attccttctt
    19321 gcatccgtgc gccacctgaa gctgtgaaca agacgactgg aagactttcc tttgttgctc
    19381 gttcgaataa tctggtgatc ttttctccga caatcgttcc catacttccc atgataaaat
    19441 taggatccat cactccaata atgaagggaa tcccctgaat ggttgcttta ccagtgagga
    19501 ctgcttcatg aagtcctgtt ttatcttgca tttttttaat tttttccgta tattcgggaa
    19561 atgctagcgg atctttggtt acaagatccg tatcccattc ttcaaaactt ttttcatcaa
    19621 taatcaaagc tagacgctgc catgcaccga ttcgaaaagc gtatccgcaa tgagggcata
    19681 ctttttcttc accgatgtct ttcgtataaa ggatatgttt gcaatttgga cactttgccc
    19741 acatgttatc aggaacagat ggcgagttag caggtttgct ctctctatta ggattgatcc
    19801 gaatatattt ctttttctta aacagagcca tctatgcgcc tcctatctcc gtttctggtg
    19861 tccaattcgg taaaaattct tcttgtaaaa atgctgtgct gtaatcacct gctatgactg
    19921 caggatgact aatcaaatcc atctgaaatt ctgcgttcgt gatgattcct tctgtgataa
    19981 attcacttaa ggctcgctgc atcttcatta atgcttcaaa acgcgtattt ccatggacga
    20041 ttatttttgc aatcattgaa tcataatatg gcgggatcgt atatcccggg taaactgcac
    20101 tgtctactcg cagtcccatc ccacctgctg gaagcagtaa gttttggatc ttccctggag
    20161 aaggagcaaa atggaaagca ggattttctg cattaatccg gcattcgatt gcgtgtcctt
    20221 ggaatactac ttcttcttga cacacattca aaggctcacc ggctgctatc tccacctgtt
    20281 tttttactaa atcgattcct gtgaccattt ctgttactgg atgttccact tggattcgag
    20341 tattcatttc catgaaataa aaatcgcctt cttcatccat cagaaactcg atcgttccgg
    20401 cattttcata attgactgct ttagctgctc gaacagcagc gtctcctagt gcttctcttt
    20461 ttgtttgtga gatcactaca gaaggagatt cttccagtac tttttgattg ttgcgttgta
    20521 aagaacaatc tcgctcgcct aaatgaatga catgaccaaa tcgatcacct aagatctgaa
    20581 cttctatatg gcgagcagga taaatgattt tttccaaata catatcatca tttccaaatg
    20641 ccgctgctgc ttcttgctga gctgaagaaa aatgctgtgg gagctcttct tttgattgaa
    20701 ctttccgaat gcctttcccg ccaccacctg cagctgcttt cagcatcact ggataaccaa
    20761 ttctgtctgc tatttccaat gcttcttcta ctgtagataa tacaccagta cttcctggaa
    20821 tgactgggac atttgcttct tgcatcaatt gacgcgcatt gatcttattt cccattgcat
    20881 cgatcgttgc acttttagga ccaataaatg tgatattgca ctcttcacac atggaggcaa
    20941 atcggctatt ttcagataaa aaaccaaatc ctggatgaat tgcttcggct tttgtcacga
    21001 ttgcagcgct cagtacttcc tgaacattca gatatgaatc aacggctttt gccgggccaa
    21061 tgcagattgc ttcatctgct aactgtgtat gaagtgcttc ggcatctgct tctgaatata
    21121 tcgctacggt ttggatccct agttcgcggc atgcacgaat gatacgtaca gcgatttcac
    21181 cgcggttagc tatcaatact ttagaaaaca tatttcacct atccaatcat aaaggttaat
    21241 tccgcttcgg ctactttttt accgtctact ttagcgattc ctttgcctat tccggctgaa
    21301 gctttcactt tcaatatctc aacttcaagg tataaggtat ctcccggtgt aactttctta
    21361 cggaattttg ctttgtccaa tccgccgaaa taagccgtct ttcccttgaa ttgttcaaga
    21421 gaaagtaatg caactgctcc tgcttgagcc attgcttcaa caatcaatac ccctggcata
    21481 acaggttctt ctggaaaatg tccttgaaaa aagggctcat tgatcgttac atttttctta
    21541 gcaacgatcc gttctccttc aaccatttct tccactcgat caatcaaaag cattggataa
    21601 cgatgtggaa tgatttcttt tatttcttgt atgttcattg ttttccctct ttcctgcttt
    21661 gcttattttt gctgaatcct aaagagtggc tgtccatatt cgacaactga ctcgttttct
    21721 acaaggattt ctgtgatcac tccgtcggcc tcactagtta tctcattcat cagtttcatc
    21781 gcttcaataa tgcagataac ttctcctttg gcaacttgat cacctacttt tttgaaagct
    21841 ggtttgtcgg gcgctggttg cagataaacg attcccacga ttggcgaaac aacctcgatt
    21901 ccatcaaata ctgccgattc tttttctttc attatttctg gagcagttgt tgcttgttca
    21961 gatatgacat tgactggctc cgaaactggc aacgtttcgt ttgtttgaac catattcatg
    22021 cctcgacttg ttttattttt attcatatac aattcaaatt gaccttcacg caaatcgaat
    22081 tccgttagcg aggattgatc aaattgactg actaattctc tgatttcatt gatatccaaa
    22141 attattcctc ccagcgtttc atgcacagaa ccgcattatg tccgccaaac cctaatgaat
    22201 tactcattgc ataagtaaaa cttgcaggtt tgctttcgtt tttgacaact gtcaagtcaa
    22261 tctcaggatc ttgtttttct acattgatcg taggtgggat aaattgatgt tctaatgcca
    22321 gcaaagttgc caaggcttcg atcccgccgg ctgctcccaa taaatgtcca gtcatcgatt
    22381 tcgtgctgct gacgtaagta tctctgaaat tttcacctaa tgcgatttgg attgcttttg
    22441 cttctgcctg gtcattggct ggtgtacttg ttccgtgagc attgatatat ccgacttgtt
    22501 ccggctgtac accagcttct tccatcgcaa gcttcattgc tttagatgca ccagaaccat
    22561 ctggagtagg agctgtcata tggtaagcgt cacagtttgc accgtatcca acgatttctc
    22621 catagatttt ggcaccgcga gcttgtgcat gttctaaaga ttcaagaact agaacgcctg
    22681 ctccttcacc catcacaaaa ccattccgat tttcgtcaaa cggaatcgaa ccacgattag
    22741 gatcagttga ttctgagagt gctgttaaag ctgcaaatcc agcaatcccc atctcacaaa
    22801 tcgttgcttc tgttcctcca gcaagaatga catcagaata gccatgtttg atgttacgga
    22861 atgcttcccc aattgaattc gttccgctag cacaagctgt tacgatagct gtacaaatac
    22921 cttttgcacc tacacgcaaa gcaatatttc cagctgccat gttggcaatc gccattggta
    22981 cgaacattgg agaaactcgt tttgtacctt tttcatgtag acgaataact tggttttcga
    23041 ttgttggaag accaccgatc ccagatccga tgatgacgcc aaaccggtct tgattcattt
    23101 tttctttatc taaaccgctc atctccattg cttctaaagc agcgtagatt ccatagatcg
    23161 aaaacatatc cattcgtttg ctatcttttt taataaaata tttatcgtaa gggaaatctt
    23221 tgacttcacc cgctaaggta atccctgttt ctgaagcatc aaatttagtg atcggtgcga
    23281 tgccattcgt cccctctttt aagctattca aaaagctgtc tgcgtcattt ccaataggtg
    23341 aagtgactcc atagccagta attaccactc gattcatttg tttgctctcc ttttcttatc
    23401 cgtgcatgac caatccgcca tcgacattga tgacttgtcc ggtgatatat ggattttgtg
    23461 ctaagaaaac tgctgtttgt gcaatatctt ctacttgtcc gaaacgctgc atcggaattt
    23521 gcttttccgc ttgttccttg actttgtctg ctaaaacttc cgtcatatca gttgtgatga
    23581 atcctggcgc aatggcatta catgtaatgc ctctagttgc agcttctcgt gccacagatt
    23641 ttgttaatcc tactacgcca gctttactag ctgcataatt tgcttgacca atatttccaa
    23701 tcaacccaga tacactagag agattaatga tggccccttc tcgctgcttc atcatttttt
    23761 tcaatacgtg ctgcgtcata ttgaaggttc caatcaaatt gatatccaga cattttttga
    23821 aatcttctgc atccattcgc atcacaagtt tgtcatttgt gattccggca ttgtttacta
    23881 acacatggat cgatccaagc ttttcttctg cttctttgat catttgtccc gctttctcat
    23941 aatcagagat gtcaccggaa actcctacgc attttacacc gaatgcttcg atttcttcta
    24001 tcttttcttt tggaatctct ccgcgaccat tcaaaatgat atttgctcca gcttttgcaa
    24061 aagctaaggc catcgctttg ccgattcctc ttgtactacc tgtgataaat acattttttc
    24121 cttttacatc cataacgttc ctccttatag tattgctatt gtttcatcaa atgtctgctt
    24181 attctcaaca cgcagaactg gtattgtttt atcgattttt ttcataaatc cgcttaatac
    24241 ttttccgggg ccgacttcga tgacttgttc gatgccgatt gtttttaact tatggatact
    24301 ctcatagaaa cgaacaggtt gcatgacttg ctgttcaagt agtcccgcga ttgtttcttt
    24361 cttcattatt tccgttgttg tgttgcttat gataggaaaa gaaggttcag agaattgaat
    24421 ctgacttagg tccttcgcca gtttttttgc tgccggttct aaaatagctg tatgaaaagg
    24481 cccgctgaca tttagaggga tcattctttt gaaccctttt tcttttaata gtaaaacagc
    24541 ttcgtctact gctttttctt cgccaccaat cacgatctgc tgaggtgtat tataatttgc
    24601 aggagatacg atgccgtact tgctagcttc atgacagctt tcctcgatcg tttcaatcgg
    24661 cgcattcatc actgcaacca ttttcccgct tccagctggg gtagcttctg tcatataagc
    24721 gcctcttttt gctactaacg caactgcttc agtgaaggat agcgcattac tagctactaa
    24781 tgccgaatat tctcctaaac tcagtcctaa agctgcatct gggatgattc catgctcctt
    24841 caataagcga taatacgcga tgctgactgt tagaatagct ggctgtgtat attgcgtctg
    24901 atccaaacgt tcattttctg taaagcaaag ttcagccata tcgtagccga gaatctcact
    24961 tgcttcatca aatgtctgct ttacaacggc ttcttcatat aaatcttttc ccataccttg
    25021 atattgtgca ccttggccac taaataagaa tgctgttttc atgtttttct ccaatatatc
    25081 cagaatatat gtttgattct tcctattcaa aaaggccgag acattcctat ttcaggaaat
    25141 gtcccagccc ccaacctaat tttaatgatt atgcagtttg tttttctacg taagtcacta
    25201 aatcttgaac cgttttgatt ccgtcttctg tttcgatttt cacgtcaaat tcatcttcaa
    25261 tttcattgat gatttggaat aaatccaagc tgtcagcttc taagtcttct tggatgtcag
    25321 tagtcaattt gatttcttca gtttcttttc ctaattcttc tgcgatgatt tcttgaattt
    25381 tttcgaatac cataataata tattcctccg atattgtttg ctttttattt ttataattta
    25441 acagtctaca actccatgag aatacttccc catgttaaac ctccgccata gcctgtaaat
    25501 attactttct gctgttttcc taaggtgatc tttccactag aaactgcttc atccaataag
    25561 atagggatgc ttgcagcaga tgtattccca tatttatcca tattggtcag gaacttttct
    25621 tgcggcatct ttacttttcg ggcaattttc tcaataattc tgaggtttgc ctgatgcaaa
    25681 agcagataat caactggttt gtctttcatg acttcttgga tattgtttgc aacgtctcgt
    25741 acggcaaaat caaaaatatc tctgccagtc atttgcaaat aatacgaacc ttctgaatct
    25801 tctgaataga acggattttt attttgctgg tagccagcgg tcaatgagct acttctggta
    25861 ccgtcagctg ctaatttttc tttcagcaat tttttctgtg gattcgcttc taagagaatc
    25921 ccacctgctc catcgccaaa caacacagca gtcgtacgat cagaccaatc gattagctta
    25981 gatagtgttt caccaccaat caccagtccc ttagttgagc cgcagcggat cattttttca
    26041 gccatgctta acgcataaac aaatcctgag cacgcagcac tgatatcaaa agcgatagca
    26101 tgagttgctc ccaatttccc ttgtacttgt gctgctacag atggtgtcgt gtaatcgggc
    26161 gacattgttg ctactaaaat aaaatccaaa tctttagggt ttagattttt ctgttttatc
    26221 aatttttccg ccactaaaat gcataaatca gaagtctcct gatttgttac acatcttcgt
    26281 tcacgaatac ccgtccttga cgaaatccat tcatcagagg tatccatcat cttggaaaga
    26341 tcattattag taataatctt ttcaggaagg acgctggctg ttgcagtaat cattccaaat
    26401 tgttccatta aatatcctca cttatagtct tgcaagaagt cgtgcaagtt tttcagtgca
    26461 tccagcaagg catgctgttc ctccgtagcc attccgtcta agatgttctt gaccatttca
    26521 cgatgaaaat gctgatggac ccgaaatagt aactttcctt ttttcgttag tcccaacttt
    26581 acaacgcggc ggtcatcttc actgcggata cgttcgacat agcctttttt tactaacttg
    26641 ttaatagcag tggtcaaggt cccaacagta attgatagtt ctttggctac ttctgaagtt
    26701 gtttttttct tgtacatccc gattgcctcg atcgtgtgca tctctgtgat tgacagatct
    26761 ttgaattgag attttttcag ctcagactct tcgattgtca aaatatcatt gaagacacta
    26821 acaagataat catttactgt ttttaaatct ggttccatgt tccaccgtcc actaattagt
    26881 ttgattatca aatcttttga tgttcaaact atatcttaac ttttttcaaa atgcaacctt
    26941 aaaagatcat ttttttacta tatgagcttt ttttaagatt ttactcattt aaaacaactg
    27001 ataaatcagc atttataatt tcttttatta gaaaaatcat ctatctcaca tattttgatt
    27061 atcaaagtat tttctgtgaa cagaactata gaattcccta aaacttgtcc attatttcaa
    27121 aatttgttat agtcttttta ttcaaagcgt aaaaggagat cctatgttaa aagaaaaaat
    27181 gaaaactctc cccatgctgc cgggtgtcta tcttatgaaa gaccgagatg gtaaggtcat
    27241 ctatgttggt aaagcaaaac ggctcaaaaa tagagtaagc agctattttc atcagaataa
    27301 acagcattca aaaaaagtat tacgtatgat tcatcatata acagattttg atttcgtcgt
    27361 agtagacacg gaattagatg ctttattgct cgagtgtcaa ttgatccaac attaccgtcc
    27421 tttttataac cgacaaatga attatttcag taattataat tatgtacata ttaccaataa
    27481 gggatttgta ttaacagata ctcctacggc tcgaacatac gggccttttc gtctctataa
    27541 aaaaatgccg tctattttgc gtataatgga agaaacttat caaatgcctt ggttgtctga
    27601 aattagtttg ttagctttgc gagtccagct tcctgaccta caggaaatga cttttgaaca
    27661 gaaaaaaaag gaactccaag ggctgtttca aggccgaaat aaaaagctac tgacttactt
    27721 gaaaaaaaga caacaacatt tcatctatca gttgaatttc gaaaaagccg gtatgcttca
    27781 aaaagatatc gaattagtta cttattttat tagacggatc caggaacaaa agcagttttt
    27841 aagaacacca tcgctcacct tcagcatgcc attagcagca gatgagagtc agaaaaagca
    27901 ctacctcgtt tgttatggtc aacttgcaga aacaatgatt acctctggtg acgtttctcc
    27961 tgacttctat tatgaaaaga aagaagctca tttatctttg aaacgtcaat tgtcaaaaga
    28021 agaaatcgat cctgtacaaa tcttgatcag ttaccgcaaa aaattagaaa aagaacagtt
    28081 tgaaattgaa ctgttaaaca aaaaagaagc tgaaaagcaa ctaaattagt tgcttctcgg
    28141 cttcttttag gcatcttcaa cttcaaatgt caattatcct aaaatttatt ggattaagtc
    28201 atagatttcc atcgctacga tatcgatatt atcaaattcg tattgctgat gagtatctgt
    28261 ttcagttaat tcaaatgtat cggtcgcttt atcataagtt actgtacact tctctacgcc
    28321 ttctttttca aaacggcgaa cttgcagttc attatctgct gactcgacca tagcctccag
    28381 tcgttttatg attgcgacta attgtgaatg tgtcatcgga ggtcctcctt ttcttatttc
    28441 tgttatattg tatcaaaagc atagcctact tgcattgatt ttctctaaaa aaactcgttt
    28501 tttatgattt tttttctggt atttttcctt caggccatca aagtttgatc aaagcttggg
    28561 ttccgtcatt ctcaaaacct ttatctgcca actcttcata tagtttcaat gcttgggtag
    28621 ttgctggcaa tacaagatcc attttttctg cttcttctaa tgcaatcttt aaatctttga
    28681 taaaatgttt gacaaaaaaa ccaggtgtgt aatcttcttt taaaatacga ggagaataat
    28741 tgcttaaaga ccagttagct gcacttccac ctgaaagcgt ctcaatcact ttctttaaat
    28801 caagtccgtt tttttgtgca tagacaagca tttccgtcat tcctgtcatc gtacctgcaa
    28861 tcatgatctg attagccatt tttgtatgct gacctttccc agcagaacca tgcaatgtaa
    28921 atgtcgtacc aaattctttg aataaaggca gtacttgatc ataaacggct tcttctccac
    28981 cgaccatgat cgtcagtgta ccattctttg ctcctaagtc accaccggat accggtgcat
    29041 ctaacgcatc tgcgcctttt tcttttgctg tttttgcaat tttttctgcc aggcttggtg
    29101 tacttgtagt caaatcaact aaaatatgtc ctgagatatc tgcagaaaaa atccccgact
    29161 gtccatagta gatttcttct acatctttgg ggtaacctac cattgtaaag agaatattac
    29221 tttgttctgc taccgctttt ggtgtatctg cccagatagc tccttctgtt actaaaggat
    29281 cagcttttgc ttttgtccga ttatagacag ctacttcgtg tcctgcttct agtagatggc
    29341 gtgcgacagc acttcccatg acgcctgttc cgataaaacc aagtttcatt ttttcgacct
    29401 cctaaaaatc aaaaatcctt gcttctatgc tagtatacgc tagaaacaag gattttttca
    29461 taaaaaatgt ttgaatttta tcttttaaat gaatttaatt ttattttgat tcgttcaatc
    29521 gagtcttctt cttcttttct tcgcatctct tcttcatgat aaacaaccat gtcttgataa
    29581 aattcgatca tagcttcgcc gaaatgtgta gatgaaatat cataaagttt agcttctaaa
    29641 acttttggat ctttaggaac ttcactggaa atataatcaa taagtgctgg tgcaaagtct
    29701 tcgtcggttt caaaagtttt ccctaatgaa ggatgatcga acaatcggtt caaataagca
    29761 tttccttcca cgacacaagg tgttccggct gccatcgctt ctgtataagt aagcccttgt
    29821 gtttctgaag tagaagcact gacaaaataa tctgccgctt tataataaag tgctacatca
    29881 ttgttgtcca cttctcctgt gaactgcaca aattcttcta actgcagttc tgagatcaat
    29941 tcctctaact cttctacata aggtcctttt cctacgataa ctaatctggc gttaggataa
    30001 gcggagatga cctgaggaaa cccattaatc aaggcttgga tatttttctc ataagaaatc
    30061 ctgcttaaag aaagaatcat caaatggttt tcctgaagac ctagtgactc ccttaatttg
    30121 ctgatatcct gctgagtgat atcagaacgt ttgaattttt caatgtcgat accagtagga
    30181 atcacgcgaa gcggtgctat tacaccatag ctgcgtaatg tatcaataac acgttcactt
    30241 ggacaaacta cacctgtcgt atgatttgca aataatctag acaagtattt tacatgggat
    30301 tgcctgatca cttttccttt accgatataa tgaaggtagt cttcatacat cgtatggtaa
    30361 gtatggatca gaggtatttt caacttctta gctaccatct tcccaagtat ccctgctccg
    30421 aattctgtat gggtatgaat aagatctagt tctagttctt tggcaaccaa ataagcatac
    30481 cacatgcctc taacaacaac tcttcgatcc ttgaaagaaa taaatggtac acttggcatt
    30541 cgaatcacat ctttttccaa cttatccgca ttaggatcgg tcgttgtaaa aatatagact
    30601 tcatgcccat gtctttctaa ttcttgtttt aatgttttga tcgatgtagc aactccgctg
    30661 acttgcggaa agtaggtatc ggtaaaaaag ccgattttca tgtttttcgc ctccaaacta
    30721 gtccttgacc tgatttactt tttttaattt gctagagact ttttcattca gtacactttc
    30781 gtatacattt ttaagttctt caccgatttt attgatactt cgctcttttg ctgtttgata
    30841 accggcttgt gtcgtactcg gtagttcttg attggtaatc tgttggatca gtcggataaa
    30901 ttcttcgttt gtcttcccca tatagcagtt cttgctatct tctaaccagc cattatacac
    30961 tggaatatct cgaacaagta cgttttgttt gcttgctaaa gcttctaaaa caacgatccc
    31021 ttctgtctct tcataagaag ggaaaaagaa tagatctgca cctgaatacg caccttctat
    31081 gatctctcca cgaatgtaac caggaaacag gacattttca ggatgatctt cttttacaat
    31141 tttccggatg ttccgaggaa tcgagtacat gggaacatga ccaaaccaaa taaatgtgta
    31201 ttcgggcatc ttcttagcaa tttctacgaa atcaatgatt cctttacgtt cgaaaaacaa
    31261 accgacacaa atgattactt tttgatccgg agacagtttg aaatattctc tgaacttttg
    31321 ttctttcatt ggatcagggt gatatttctc taagtcgatc ccattggaaa tagcttgaat
    31381 cggcacacgg ataccatagc tttccaacaa ctgttttgaa taaggtgttg gcgtgatcag
    31441 atagtccgct ttttggtaca atcctaccag atattttttt acgataggag aaagctggtt
    31501 cgatccgata aaggaatttc ggaaatcttc ctctgtagaa tgcgcatgat agacaacttt
    31561 ttttccttct cttctggctt tattgaccat attatgacta ttgattccgt atgtattgat
    31621 gtgcaggatg tcataatctt ctttttcatc tagtgtataa gagataccga cttccgtcag
    31681 agcacgtttt tgatgatcaa gcgcacgccc gattccagat tttgcaagca tcttttcact
    31741 ttcaaaatat aataatacct tcaccttacg tcccccttca cttatatagt ataacatagc
    31801 ctacaaactg tcactcaaac ttaagcccta tttttgtcta ttcttactga caaaaacgtt
    31861 ttcttaaaaa agaacaaaaa aactggcgta gctcttttac aagccacacc agcttttgat
    31921 acgttgttta ttttacatat tcatgaacaa gttcaacgac ttcttccatc atatcgcatt
    31981 ctttcaatgc acgatcagca agttcagcca ttttcgctgt gtccaagcgt ttcattaaac
    32041 tacgcgtttt aagaatagat gtcgcactca ttgagaactc atctagaccc atacctacta
    32101 gcaatggaac agctgtttga tctccagcca tttctccaca catacctgcc cattttcctt
    32161 cagcgtgtgc tgcatcaatt acatttttga tcaaacgtaa aattgatggg ttatatggtt
    32221 ggtacaagta agaaacgcgt tcgttcatac ggtctgctgc cattgtgtat tgaatcaaat
    32281 cgttcgtacc tacagagaag aaatctactt cttttgcaaa cttgtctgct aagactgctg
    32341 ctgctggaat ctcgatcatg atgccgactt ggatcgtatc agatacttcc ttgccttcac
    32401 ttatcaattt ttgtttttct tcttcaaaga tcgcttttgc tgcgcggaat tctttgagtg
    32461 tagctaccat agggaacatg atacgtaaat taccatgaac agatgcacga agcaatgcac
    32521 gcatttgtgt acggaacatt tcgtcgcctt gttcagataa actgatacgc aatgcacgat
    32581 atcctaagaa tggattcatt tcatgaggta attgcagata tggtagttct ttatctccac
    32641 cgatgtccat tgtacgaaca actacaggtt ttccttccat accttctaat acagctttgt
    32701 aagcttcata ttggtcatct tctgttggga agtctggaga atccatatac aggaattcag
    32761 tacggtacag accaactgct tctccaccat tattatggac accaactaga tcttttggtg
    32821 ttccgatgtt tgcagctaat tcaaaatgct tgccgtcagc tgtgacagtt tctgcatttt
    32881 ttaatttttc ccattctgct ttttgtgctg cgtaatctgc acctgctttt tcaaattcag
    32941 ctttttgttc atctgtagga tcgatgatta catcgccttc gatcccgttg acagccaaaa
    33001 tatcgccttc tttgacttta gcagtaattt cttttgtccc aacgattgct ggaatttcta
    33061 aagaacgtgc catgatagca gaatgtgaag tacgtccacc aatgtctgtt acaaacgctt
    33121 ttacaaaatt gcgatctaat tgtgctgtat cacttggagt caagtcatgt gcaacaacga
    33181 ccacttcttc gttgatcatt gatggatttg gtaaagtaac gcctaataag tgcgctaaaa
    33241 tacgtttagc aacgtcacga atatctgcag cacgctcttg catataagca ttatcttcca
    33301 ttgcttcgaa cataccgata tacatatccg ttacttcttt tagcgctgat tcagcattta
    33361 cgctgttgtc tttaatattt tgcttgattt gacctaccat ttctggatct gaaagaacca
    33421 tcaaatgggc atcaaatact tgcgcttctg cttcacctaa gctttgcgct gctttttcac
    33481 gaatttgctg caattcttca gtagatttag ctaatgcagc atccaaacga gcttcttcag
    33541 ccgcagtatc ttctactgtt gccttactga atgttaaatc cggttgaact agcaggtaag
    33601 cttttgcaac ggctacaccg tcactagcgg caatcccttt tagcatttca accattattc
    33661 agataagcct tctttcttca ttgtttcaac gattgctgcc attgcatcag cttcgtcagc
    33721 accttctgca gtaatagtaa catcagaacc ttgacctaca cctaaagaca taacgcccat
    33781 gattgatttc aagtttactg atttaccttt atactctaag tttacatcag agttaaattt
    33841 gcttgctgtt tgtactaata gtgtagctgg acgagcgtgg atcccagttt ctgctactac
    33901 gtgaaattct ttcttttcca tattaatcgg tctcctttaa gtgagtgttg tttttatgtg
    33961 agggttttct tttttagtaa ttcagagaat cctaacaaat gccacccttt catctgtaaa
    34021 gattaacatt ttttttcgtt agatacaaca gttttcattc aatttcagat aaaagtattc
    34081 aaattattcc ggattctttt tcatcctttt cttcacattt tataacaaac gtgtttattt
    34141 cctttttctt gtcgctttct cttctcctga cgtttatcat tctttccttt gaccctcttt
    34201 gttttcatat gaaacgaatt acttgcttcc ctttttattt ttagtataat aagagtcaaa
    34261 ggtcaggaat ggtcaataga gatttcacct tttctacctc ataaatctct taaaaaacta
    34321 ggggttattc ttttacctca tgaaaaacga gatgtaaaat atggatgtac ccatttttgt
    34381 gaaaggacgt gaatgattca tgctttgtca aaactgcggc aagaatgagg caacgattca
    34441 cttgtatgcc actgtcaatg gtcagcggac acaactcgat tactgtcaga gctgttatca
    34501 aaaaatcaaa aatcaacaaa atggaggtct gactaatatg gcccaaaatg atccatttgg
    34561 atttggcagt ttggacgatc ttttccgttc catgtctcgc caaatgcaac agcaaggaaa
    34621 ttatgagcaa acaccaccaa cacaatttgg cggaaacaac aacttcaatg gtggtcagcc
    34681 acctcaaggc aatacagaag gtttattggg agaatacgga atcaatatca cagaacaagc
    34741 acgacaaggt gatatcgatc ctgtgatcgg acgcgatgac gaaatcaaac gagtcattga
    34801 aattttaaat cgccgaacca agaacaatcc tgtcttgatt ggagaaccag gtgttggtaa
    34861 aacagcagtt gttgaaggtt tagcacaaaa aatcgtagat ggtgatgtac cgcaaaaatt
    34921 aatggacaaa gaagtcattc gtttagatgt cgtatcttta gtccaaggta ctggtatacg
    34981 aggacaattt gaagaacgta tgcaaaaatt gattgaagag atccgtcaag cagaaaatgt
    35041 gatcctattc atagatgaag ttcacgaaat cgtcggtgct ggttctgctg gtgatggaaa
    35101 tatggatgct ggtaatattt taaaaccagc tttagctcga ggagaattgc aaatggttgg
    35161 tgctactacc ttaaatgagt accgcatcat cgaaaaagac gctgctttag aacgtcgtat
    35221 gcaacctgta cgggtagatg aaccaactgt cgaagaaacg atcagtattt tgaaaggttt
    35281 gcaaaaacgt tatgaagact atcatcatgt aaaatatact gatgaggcca tcgaagcagc
    35341 cgcaacttta tccaatcgtt acgtccaaga tcgcttcttg ccggataaag ccatcgattt
    35401 gctagatgaa acaggttcta agaaaaactt gacgatccaa atcgttgatc ctaaaacaat
    35461 cgagaaaaaa ctgcaagaag cagaagaaca aaaagtttta gcttctcgag aagaagattt
    35521 cgaaaaagca gcttattatc gcgatcagat caataaactt caaaaaatga aagaacgtca
    35581 gctcactgaa gaggaaacac ctgtgattac cgaaaaagat atggaaaaaa tcgttgaaca
    35641 acggacaggt attccagtgg gtgaattaaa agaaaaagaa cagacacaac tgaaaaactt
    35701 agcagatgac ttgaaagctc atgtcatcgg acaagataac gctgtagatc gagtagcgaa
    35761 agcgattcgc cgaaaccgtg ttggattaaa caaacagaat cgtccaatcg gctccttctt
    35821 atttgttgga ccaactggtg taggtaaaac agagcttgcg aaacaacttg cctacgaact
    35881 attcggttca caagattcaa tgattcgttt cgatatgtct gaatatatgg aaaaacatag
    35941 tgtctctaaa ttgattggtt ctcctccagg ttatgtcgga tacgaagaag ctggtcaatt
    36001 aacagaaaaa gtacggagaa atccttacag tcttgtcttg ttagatgaag tagaaaaagc
    36061 tcatccagat gttttgcata tgttcttgca aatcttagat gatggtcgat tgacagatgc
    36121 acaaggaaga acggtcagct ttaaagatac gatcatcatt atgacaagta atgccggaac
    36181 tggtaaagta gaagcaaacg ttggttttgg tgcggcacgc gaaggtgtta ctcgttctgt
    36241 attgaaccaa ttaaacaact actttacacc agaatttctg aaccgttttg acgggatcat
    36301 cgaattcagt gcattatcaa aagaaaactt gatgacaatc gtcacactaa tgctagacga
    36361 tgtcaaccaa atgctggcag cacagcaact tcacatcgaa gttcctacga atgtcaaaga
    36421 aaaattagtt gacttaggct atgatccatc tatgggtgct cgtcctcttc gacgcacgat
    36481 ccaagaacaa atcgaagatg gtatcgctga attttatctt gatcaccctt ctatccatga
    36541 gttgaaagca aaactggata aagatggaaa aatcatcgtt acttctaaac cagaacgttt
    36601 ggctaaagaa tcagccgaag aaacggctga ataaatccag ttttatagcg tgagacggta
    36661 tttctttgag aaatgccgtc tcattctttt ttcagaaaag tcaaaatact gttcatttta
    36721 taaaaaagaa attataataa gagaaacaag caattaaaaa tacataaaag aggtgagcgc
    36781 catgaaattg gtaaatgtaa caaacagcca ttcccgtctt gtattaaacc agcttgaaaa
    36841 cactgatgcc catctagtca aggtctacac agccggaaat accactattg tctacactga
    36901 agcccctgaa cataatgaaa ttctgctgat caatgacaaa cgtaaaatcc agccgaaaga
    36961 aatcgaagat gctaaaaatt atttcttaga taaaatcaaa gacgccgttt accacgagga
    37021 tgaaatcaaa gtaatcgaat tggcaggcct tgttgaaatc tcgattccaa aacatgaatt
    37081 aggcgctaca ttagccgtgt aaacaaattt tgaacataat aattaaagag cgtgggacaa
    37141 aagtaaagaa cacttttgtc tcacgctcta aacacgtata aacggcgaaa gcagaagcaa
    37201 ctccttcgga aataagctga aattcacgaa aattgctttt caaatttttg tgaattccag
    37261 cttatttctt ggagttaaac gcttctgtct cagcctcttt ttctttctag ctttttgatt
    37321 tttctctttt cttttgtact tttctctttt cattttcagt tctacgcgtg tctttatttt
    37381 taactttttc ctctttatgg atgattgatc gtactttttg tgcaatttgc tcgtttttgt
    37441 cccagtcttt tacatctaat aatcgacata atcgtaacat ctcttctttt ttctgttttt
    37501 ttctttcacg tctttgccat tctgtttcca tgtgtcacac tctcctttct ttaatcatat
    37561 gtacgcaaaa taatttttat atttttttga ttagacattt ctatgatttt aatatagtaa
    37621 aaagagccgt cacggaaaat ccgtcacggc tctaaacaaa atatgagagg ctgtttttgt
    37681 ttggctattc ttattacttg atgcagggca gcttgtgtca agacttcttt acatcaaact
    37741 ttttaatttt acattgggat atttatccgc aaaccagcgt tctgcaaatt ggttctcgaa
    37801 taagaacaac ggttggtcga aacggtcacg agccaagata ttgcgacttg aactcatctt
    37861 ctcatccaaa tcttctggat cgatccagcg agcgattttg tgtcccattg gagacatgat
    37921 tacttcggcg ttatactcat ttaacatacg atattggaat acttcgaatt gtagctgacc
    37981 aacagctcca atgatatatt cttccgttag atatgtttta taaagctgaa tcgctccttc
    38041 ttgaactaat tgatagattc ctttgtggaa ggatttttgt ttcatgacat tttttgcagt
    38101 cactttcata aacagctctg gagtaaatga agggagttct tcataagcaa cttttagttt
    38161 tccttcgaac aatgtatccc caatctgata attgcctgta tcatatacac cgatgatatc
    38221 gcctgctact gctttttcga cgttttctct cgaatctgcc ataaattgtg tgacattgct
    38281 taatttcagt tttttatttg tacgttccaa ccagacatcc attcctcgtt cgaatgttcc
    38341 agaacagatt cggacaaaag cgattcggtc acgatgggct ggattcatat ttgcttggat
    38401 cttgaatacg aaacctgaaa attcttcctc ataaggactt accatctgat catcttgtgt
    38461 tttgtgtcca taaggagctg gtgccaattc aacgaaagtc tctaaaaaag tctgtacacc
    38521 gaagttagtc aatgcagaac caaaaaatac tggtgtctga tcgccacgag caattttttc
    38581 ttgattaaat gcatctccag cctctttgat tagttctact tcttctaaga cttgttcata
    38641 taaggaattt tcagttagag gatgattttc gggaagcagt ccatcttcat ccaattctac
    38701 taatcgttca tcctgataat tttccggacg ataaaactct acacgattat ggtagatatc
    38761 ataaagacct tctagccctt tacccatacc gattggccaa ttcatcggat aagattcgat
    38821 atctaatagc tcttctaatt cttctaacaa ttccaatggt tcacgaccat cacgatctag
    38881 tttgttgata aaagtaaata tcgggatgcc acgttttttt acaacttgga ataatttctt
    38941 tgtctgtgct tcgatccctt ttgcactatc gattaccatg accgcactat ccacggccat
    39001 caaagtacga taagtatctt cagaaaaatc ttcatgtcct ggtgtatcca agatatttac
    39061 tcgtttccct tgataatcaa actgcataac agaactagta acagaaatcc cacgttgttt
    39121 ctcgatttcc atccagtctg atttggcaaa attacctgtt tttttgcctt ttacggtccc
    39181 ggcttgacgg atagccccac caaacaatag taattgttct gtaatcgttg ttttcccagc
    39241 atccggatgg gaaatgatcg caaaagttct gcgattgtcc acttgttgct ttaattttgg
    39301 attattcata acctaactcc atttcttcca ttcaattatt tatattttct ctaggcacag
    39361 attgtccgat ctcttaaaga aagacaattt catatagggc tgtgacaaaa gccgtgtagc
    39421 agtctctttt tccgagtaaa cggcgttcta gagacagcct atcagcaata agcccaccca
    39481 agccaaaaat acgaaaagct gtttttgctt ggctgctctt attacttaat gcaggatagc
    39541 tttttcacaa cctttgtcaa ctactacaac tgaatcagta tagcatggat tcagcgaatg
    39601 aaaaagccac caaaccataa gagtcaaata tttttttgtc agctgactaa aagaaaagac
    39661 gtgttgcttg tttattcaag caacacgtct ttcataacca agtttccaat tatcttcttg
    39721 gctcgtcatc ttcgaattct tttctgaagt atcttcgttc ttcttcaggt tccgcttctg
    39781 tttcttccgg atcatgaaaa atgacacgga ttttaaggat tcgagaacct tccatttctt
    39841 cagaaaccag cgtaatatta tcgacatcaa acgataactt ttcgccttca tccggaatca
    39901 tgcctaatgc tgtaatcaaa taaccagcca tcgtatctac atcactcata tgcagatcac
    39961 tgtcaaaagc ttcattgaac tcatcaatca gcatacgtcc ttggatgata tattcgtgtt
    40021 catcgatttt ttcataaaga ttctcaactt catctgattc atcatcgatt tctccgacga
    40081 tttcttctaa aaggtcttct agtgttgcta acccaacgac gccgccatat tcatctaata
    40141 aaatagccat ctgattctgc gtctttttca tttcatataa cagatcatca ataaagaccg
    40201 tttcaggaac gaataaaggc tcctgcatga ttttcttgat atctaaatta tcaaagccga
    40261 atttatgggc agcttttagt aaattctttg tatgaaggat tccgactact ttatctttgt
    40321 cttcgttata aacagggatt cttgaatagt tttcggataa aacttcattc acattttctt
    40381 ccacagtgtc gttgatatca atcataaatg catccgttcg tgggaccatg acttctcggg
    40441 caactttcgt atcaagagaa aaaacccctt ggagcatttc taattcttca ttattcaata
    40501 cgccttcgtt ttcaagcata taacgcattt catctctggt catttttgaa tcttcatcat
    40561 caaaagtcat cggcgtgata cgcgccaata aacttgtgga agcagaaagc agccagacga
    40621 agggcttagc tactacacca atcaagcgta tcagccctga agtgaacttt gcgacttctt
    40681 ctgatttatt taaagcaata cgtttagggt acaattctcc aaaaacaatc gatacatagg
    40741 tcaaaatagc cagcacaatg atatttgcaa tattttttgc cgctgtgccg ccacctaata
    40801 ccggagctaa ccgttccgat aaagtattag ctagtgaagc accagacaaa atgttgacca
    40861 aagtgattcc tacttggatt gtcgatagga aattatttgg attctgcaat atttttaaaa
    40921 gcttttgaga tttcacatct ccttcatcag ctttttgctc gattcgattc ttattgatcg
    40981 aaacaacagc aatttcggaa gctgctaaaa aagcattgat caatgtcaaa acgatcaata
    41041 ataaaatctg cgctaacagc gactgactct cagggtcagc attcataatc gcattctctc
    41101 cttataaaat taatttttag tttacgatag aaaaaaacgt ggcactatag ccacgttaaa
    41161 atggtatcac aaagcaattt tctttgcaat aaaaacaagt gtactaaaac tacctacgag
    41221 gtcgtagcaa ttttcttctt gttttcattt tgcttgtctt ctttgacgat tttgattata
    41281 taggaaatga tcgtcttgca gattgcgtaa aaaggaacac ctaagaagat accaagcaat
    41341 ccggcaatat ttccagctac tagaagaacg ataatgatcg ttaatggatg gattttcagt
    41401 gatttcccaa ttacattagg ataaatgata ttcccatcca actgttggac gattagcaca
    41461 accacacaac aaagtaatgc ttttaccgga tcattgaaga ctgttactag aaatgcaggt
    41521 gctagtccta gataaggtcc taaatatgga attaggtttg tcaatcccgc aatgacccca
    41581 aataagaaag cataatccac accaattacc atatatccta aaaatgtgaa ggtaccaacg
    41641 aataaacatt cgattgcttg tccgctaatg taattagcca atgttttatt cagttgcccc
    41701 aataactcca caatttggtt tcttcttttt tctgggaaaa actgttggat gtttggcact
    41761 agtttttctc cgtctttcaa catatagaac aagatgaatg gtgctgtaat gattactacg
    41821 gttgccgaag cgatcgttcc aacgatcgaa cctaaactat tggatactcc actaaggaat
    41881 tgctgaatga ttgtcccgta agaaatgtct aattgctcaa aatatttatt gatatctact
    41941 tccttgaaca aaggcaattc ggctacctct tttaaccagc tttctacctg tttgatgaaa
    42001 tcaggcatat tagatgccaa tgaggaaatt tgctgtacta gacttgggat gacactaagt
    42061 aaaatccaaa taattgctgc aactaaaagg agcagcacaa ttgcgacagc ccatattctt
    42121 ttgatttttg ctttcatcaa cagcttgaca ataggattca ataaatagta aagaaagcct
    42181 gcaatcagta caggtgcaaa taacgtggaa aaaaatgtcc cgatcggttc gaaaataaag
    42241 tttatttctg atgaaatcat gatcaatgca gctatgatca ataattcaag cgaccaaaac
    42301 attagtttag actgtctaag tttttcaaac aatagatttc ctcctttctt tcttactagt
    42361 atatattata ttcgttaaaa attcttttat tcttttttta tt
//
LOCUS       DAZULR010000025        37773 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.025, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000025 DAZULR010000000
VERSION     DAZULR010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37773)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37773)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37773
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.025"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            245..2410
                     /gene="acm"
                     /locus_tag="ACG8ZV_001485"
     CDS             245..2410
                     /gene="acm"
                     /locus_tag="ACG8ZV_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HFS4996834.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(2682..3167)
                     /locus_tag="ACG8ZV_001486"
     CDS             complement(2682..3167)
                     /locus_tag="ACG8ZV_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HFS4996835.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    3257..3602
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            3647..4288
                     /locus_tag="ACG8ZV_001487"
     CDS             3647..4288
                     /locus_tag="ACG8ZV_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFS4996836.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIIMKQVEGKLNYYR"
     gene            4307..4942
                     /locus_tag="ACG8ZV_001488"
     CDS             4307..4942
                     /locus_tag="ACG8ZV_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFS4996837.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            4960..5775
                     /locus_tag="ACG8ZV_001489"
     CDS             4960..5775
                     /locus_tag="ACG8ZV_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HFS4996838.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            6094..7530
                     /locus_tag="ACG8ZV_001490"
     CDS             6094..7530
                     /locus_tag="ACG8ZV_001490"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFS4996839.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            7719..10166
                     /locus_tag="ACG8ZV_001491"
     CDS             7719..10166
                     /locus_tag="ACG8ZV_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HFS4996840.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            10396..11463
                     /gene="rlmN"
                     /locus_tag="ACG8ZV_001492"
     CDS             10396..11463
                     /gene="rlmN"
                     /locus_tag="ACG8ZV_001492"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HFS4996841.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            11453..11659
                     /locus_tag="ACG8ZV_001493"
     CDS             11453..11659
                     /locus_tag="ACG8ZV_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996842.1"
                     /translation="MPNNRILLVFSITIKGAVFLIKELFNLNKRKDSIAKAIKLFLTR
                     KTLIKQRNVLNLMTACLMGVLAII"
     gene            complement(11656..12759)
                     /locus_tag="ACG8ZV_001494"
     CDS             complement(11656..12759)
                     /locus_tag="ACG8ZV_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HFS4996843.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            13312..13860
                     /gene="aac(6')"
                     /locus_tag="ACG8ZV_001495"
     CDS             13312..13860
                     /gene="aac(6')"
                     /locus_tag="ACG8ZV_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HFS4996844.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
     gene            complement(14107..14226)
                     /locus_tag="ACG8ZV_001496"
     CDS             complement(14107..14226)
                     /locus_tag="ACG8ZV_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HFS4996845.1"
                     /translation="MVFQKPLNNFRYIVYYCHTKIKKNKQKETVTKVLSQSLI"
     gene            14405..16066
                     /locus_tag="ACG8ZV_001497"
     CDS             14405..16066
                     /locus_tag="ACG8ZV_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HFS4996846.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(16136..16483)
                     /locus_tag="ACG8ZV_001498"
     CDS             complement(16136..16483)
                     /locus_tag="ACG8ZV_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HFS4996847.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            16567..17508
                     /gene="opp3b"
                     /locus_tag="ACG8ZV_001499"
     CDS             16567..17508
                     /gene="opp3b"
                     /locus_tag="ACG8ZV_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HFS4996848.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            17509..18552
                     /locus_tag="ACG8ZV_001500"
     CDS             17509..18552
                     /locus_tag="ACG8ZV_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4996849.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            18558..19628
                     /locus_tag="ACG8ZV_001501"
     CDS             18558..19628
                     /locus_tag="ACG8ZV_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4996850.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            19618..20571
                     /locus_tag="ACG8ZV_001502"
     CDS             19618..20571
                     /locus_tag="ACG8ZV_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4996851.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            20583..21593
                     /locus_tag="ACG8ZV_001503"
     CDS             20583..21593
                     /locus_tag="ACG8ZV_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HFS4996852.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(21878..22699)
                     /locus_tag="ACG8ZV_001504"
     CDS             complement(21878..22699)
                     /locus_tag="ACG8ZV_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFS4996853.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(22796..23074)
                     /locus_tag="ACG8ZV_001505"
     CDS             complement(22796..23074)
                     /locus_tag="ACG8ZV_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996854.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            23342..25351
                     /gene="metG"
                     /locus_tag="ACG8ZV_001506"
     CDS             23342..25351
                     /gene="metG"
                     /locus_tag="ACG8ZV_001506"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HFS4996855.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(25830..26417)
                     /locus_tag="ACG8ZV_001507"
     CDS             complement(25830..26417)
                     /locus_tag="ACG8ZV_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996856.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            26592..27914
                     /locus_tag="ACG8ZV_001508"
     CDS             26592..27914
                     /locus_tag="ACG8ZV_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFS4996857.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            28069..28845
                     /locus_tag="ACG8ZV_001509"
     CDS             28069..28845
                     /locus_tag="ACG8ZV_001509"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HFS4996858.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            28838..29407
                     /gene="rnmV"
                     /locus_tag="ACG8ZV_001510"
     CDS             28838..29407
                     /gene="rnmV"
                     /locus_tag="ACG8ZV_001510"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HFS4996859.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            29400..30284
                     /gene="rsmA"
                     /locus_tag="ACG8ZV_001511"
     CDS             29400..30284
                     /gene="rsmA"
                     /locus_tag="ACG8ZV_001511"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HFS4996860.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            30735..31364
                     /locus_tag="ACG8ZV_001512"
     CDS             30735..31364
                     /locus_tag="ACG8ZV_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996861.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESVQGYAKKTTY"
     gene            complement(31487..32596)
                     /locus_tag="ACG8ZV_001513"
     CDS             complement(31487..32596)
                     /locus_tag="ACG8ZV_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4996862.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            32805..33227
                     /gene="mgsA"
                     /locus_tag="ACG8ZV_001514"
     CDS             32805..33227
                     /gene="mgsA"
                     /locus_tag="ACG8ZV_001514"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008929 - methylglyoxal synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006007 - glucose catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019242 - methylglyoxal biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HFS4996863.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     regulatory      33414..33512
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01831"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="THF riboswitches regulate genes encoding folate
                     transporters and folate metabolism; They are most commonly
                     found in Clostridiales and Lactobacillales; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="tetrahydrofolate"
                     /db_xref="RFAM:RF01831"
     gene            33550..34086
                     /locus_tag="ACG8ZV_001515"
     CDS             33550..34086
                     /locus_tag="ACG8ZV_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HFS4996864.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(34126..35889)
                     /locus_tag="ACG8ZV_001516"
     CDS             complement(34126..35889)
                     /locus_tag="ACG8ZV_001516"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4996865.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLLSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(35892..37607)
                     /locus_tag="ACG8ZV_001517"
     CDS             complement(35892..37607)
                     /locus_tag="ACG8ZV_001517"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4996866.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
BASE COUNT        12481 a         6648 c         7782 g        10862 t
ORIGIN      
        1 atagattgaa aaaatgaaag caataagtaa aataaaatga atatatgcga aaaaataatt
       61 tacattagga aaaaccttgt aaaaacagtt ttttggcata tttatttttt ataaatattt
      121 gtaaaataac tatcaatttt ttagttaaaa gattggaaat gagtggggga ggaattgaag
      181 aaaggatttt tgagagatga tatagtaggt tttattttta gttaaaatag gggagataga
      241 aaaaatgaaa aagtgtagaa atattatttt atcaatgtta tttattatta ctaatataac
      301 atcactgatt cctgttcatg tctatgcgga tgcaggcaga gatatcagca gtaatgtcac
      361 ttcgttgacc gtggacccaa cgaatattac agatggagga aacataaaag taaaattctc
      421 gtttgacgaa aaaaaacaaa atatccaacc aggtgattat ctttggatca attggccaag
      481 tgaaggaaat attcgcggtg aaggattcca aaaagaaatc ccattaatga ttgaaaataa
      541 aaatgttgga actttaacgg tcagaaaaga ttctgcgcag gttgtgttta atgaaaatat
      601 taaaaaccta gactcagtag aaggttgggg gcaatttgag atacaggcca gaaacgtaac
      661 cgataccggt gaagaaaata cgggaccatt caccgtgacg agcggtgata aaacagctac
      721 tgtaaatgtg acaaagccag cttctggttc ttcttctagc gttttttatt ataaaacagg
      781 agacatgcta cctgaagata ctaagcacat tcgatggttt ttgaatatta acaataacgg
      841 cacttatgtt gaacaaccag ttaaaatcag tgatgaaatc caaagtggac aaagattaga
      901 tccaagtacg tttgaaatta atcaaataca cttaggtgaa cagaaggttt atagaggaga
      961 agagggaatc caacaatttt tacaagattt ccccagcgct acatttaatt tttcagtaac
     1021 tgataattac attgaaataa ctataccaaa aaactttgtc aatcttagga aaataatggt
     1081 gagttataag acgatcatag aaaacccaga acaaataaat tttgagaatc attcggaagc
     1141 ttggtttaaa gaatttaata aacctgctgt tgatggagaa agtttcaatc atacagttaa
     1201 aaatatttca gcttctggtg gagtcaacgg tacagttaga ggcgaattga agattttcaa
     1261 atatatcaat gacacagaga ttggtatccc aaatgtgact ttcgaattaa gacgagcaga
     1321 tgaacagcct attcaaggac agtctagtat cctgttgact tcgaatgaac agggagaagc
     1381 tagtatcaaa ggcctgcaag taggagacta tgttgtaaaa gaaaaagaag cacccaattg
     1441 gattgatttt gatccactaa gttcaaatga actcaaattc tccataaacg aaaatgatac
     1501 agagggagtc agtttaccta tttataacaa gaaaaaggtt acgaacatca cagcaactaa
     1561 aatttggaac ggtggaacca ctccaagacc gagtatttat tttaaattat tcagagcaag
     1621 tacaaacaat tgggaaccag ttcctgatgc agaaacaaaa cgattagaca atggaataac
     1681 ttcagtgact tgggaagata tccaacagta tgatgatagt ggaaacgaat atacgtttaa
     1741 agtgcaagaa gtagatcaaa acggaaatga ttatgtccct tcaggttatc aaaaaattga
     1801 aaacgggcta gtcgttacaa atgagaataa agaagtcatt tcagtctcag gacaaaaaac
     1861 atgggaagac aatgagaacc aagacggcaa acgaccgacg acgatcacag taaatctatt
     1921 agccgacggt caaccgatcc aacacaaaga agtaagtgaa aaagatgatt ggcgctatcg
     1981 tttcacaaat ctgccaaaat acagagacgg gcaagaaatc atctatactg taacggaaga
     2041 caacgtgccc gaatacagta cgacgattga cgggtataac atcaaaaaca gttatacacc
     2101 ggaaaaaaca aatatatcta taccaggtag ccatataaca ccgtggaaaa attttccaga
     2161 gaagacagag agagagaaaa ttagaaatct attctctcaa aaattgcaaa tatttgctca
     2221 tacaggagaa tccagcgaac aaagaagcaa ttatattagt aagagagctg tacctaaaca
     2281 gataacaaat aaatcaaaaa gcattcttcc taaaacaagt agtaaaaaat ctagttttgc
     2341 tgtaatcatt ggtttattga tagtaactat ctgtgctggg atattcttac aaaaatataa
     2401 aaaagtttag ttagaatata atattttttg ttaaatatga ctgaaatcaa aagaataaaa
     2461 ttccgattta taatcgaaaa aagaagcatt tttatatatg cttctttttt cgtagaatca
     2521 ataaatatgg atttggctaa ctatggaaga atactcgtat tagttttcag cgttcatact
     2581 agttgttaca ttgtttgatt ggccaaaaga atttctgata tattttgtgc taaataaaga
     2641 aaaagacgct tgaattggga aataagaaaa ctactctatc attacaaatt ttcataaact
     2701 ggcagatgtt ctaagtaaac aagtatcttt tcaaagtcgg aaaaatccat aatcaacgta
     2761 gtggtattga tatttggatg aaagcctacg gtatcttgac gatcaatagc agcatcgatc
     2821 acgacttgga tttttttctc tttgtcgtgc atcaatgcta atggagtcac tgtacctgct
     2881 ggaacgccta ggaggtcagg aagctgttct tcagaaacaa aagataagcg cttttctttt
     2941 aattgttcag ctagttgttt taaatcggcg tgcttttcat caggcaagat gacaagatag
     3001 atttgttttc cttttcttga tttcaataat agatttttta cttgcggacc aggtagggaa
     3061 aaagggacat ttttgactga cgtaatcgca ggatgatcga ctttttgaaa agagataccc
     3121 agttttttta gtagttcata agcttcttgt tcggttgcac gactcatcgc gcatcaccct
     3181 ccttttttta ttagtgtatc ataaaaaaga gttgacaaat gaaaaataat catgtaaatt
     3241 acacgtaaag ttaaaacaaa tgacatcgaa aagaagagta gccgttaggt gtttttagag
     3301 agtctctggt tggtggaaag aggcagcagt taaccgtgaa acacatcttg gagtcgattt
     3361 tctgaagcgt atagtaggaa aatccgggga gcccgttaca gctgcggtcg ttgctagatg
     3421 accagataag gctggctttt ccgtgaggag tcggtaaaaa aaggtggaac cacgtgatta
     3481 acgtcctttg atcttcggat caaaggactt tttgttttca tctgaacggc aacgactgtg
     3541 tgaggttttt tctgcaagga aaaaataaac agaggtggaa ccacgtataa tacgtcctct
     3601 tggcatttgc caagaggatt tttttatttt aaaggaggaa aagaagatgg agtatttgat
     3661 tgaagttatg ccgcaattat tagtaggagc actcacaaca ttgaaattat ttttatttac
     3721 cttgattggc tcattaccat tagggattgt tttagcatta ggattgtctt tgcattttaa
     3781 gccgctacgc tacttgcttc aaacatatgt atgggttatg cggggaacac cgctgttgtt
     3841 gcaactgatt tttatttttt atgggttgcc gacgattggg atcgtttttg atcgtttcga
     3901 agcagcactc attgccttta tcttaaacta tgcagcttat tttgcagaga tctttcgtgg
     3961 agggatacaa tcgattcctc aaggtcaata tgaagcagcg caagttttgc aattaagtcc
     4021 ctttcaaacg gtgacgaaaa tcgtcatccc acaagtgaca aagattgttt taccttctgt
     4081 agggaatgaa gttatcaact tggtcaaaga ttcttccttg atctatatat taggtttagg
     4141 tgacgtaatg cgtgctggga aaatcgcgat ggaacgcgac gcgactttac tgcctttgct
     4201 aggcgtggca atcatctatc ttacattgac tggtattcta acaatcataa tgaaacaagt
     4261 tgaaggaaaa ttaaattatt accgctaact gataggagga agaaatatga ttgaattgaa
     4321 gaaagtgaac aaagcatttg gtgaaaaaaa aataatcaaa gatttgaatc taatcattcc
     4381 agatgggaaa acattagcta tcgtaggtcc ttccggtggc ggtaaaacca cgcttttacg
     4441 tatcttggct ggcttagaaa gttctgacag cggagaattt tatttagacg gtgtaccgtt
     4501 caacccattc gagcttaaaa tgaaagaaca agttgtagga gtcgtattcc aagacttcca
     4561 gctatttcca catctgaata tttttgaaaa cattacctta gcaccaaaaa tggtattgaa
     4621 acagacaaaa gaagaataca ccaaaaaagc agaagaatta gcggcttcat tagggattag
     4681 tgatttattg aatatctatc cttatcagct ttctggcgga caaaaacagc gggtagcgat
     4741 tgccagagca ttggctatga atccacgggt attggcttat gatgaaccaa caagtgcttt
     4801 agatcctgaa ttacgccagc aagtcgagcg tttgatccta tcattgaaag aagatggggt
     4861 aacccaaatt attgtcaccc atgatttagt atttgcagaa aatgtcggtg atcaattact
     4921 aaaagtttcc ccaattcatt aagaaaggag aagatagaga tgaaaaaaac cagttttcta
     4981 ttcgctttga tcgcaggtct tcttcttttt gcaggctgtt cgaacaaaaa aacttcagca
     5041 gataattggg cgactatcaa cgaagagaaa aaaatcgtta taggtttaga cgatacattt
     5101 gttcctatgg gatttagaga taaagacggg aagctcacag gatttgatat tgatttagcc
     5161 aaagcagtct ttgaacaata tgggattacg gtagactttc agcccattga ctggtcaatg
     5221 aaggaatttg aactgaacaa tggaacgatc gatttgatat ggaacggcta ttccaaaacg
     5281 ccggcaagag aaaagaaagt gcaatttaca aaaccttata tggaaaacga tcaagtgctg
     5341 atcacaccta aagaatcagg aatcacaaac tttggacaaa tgaataataa gagattaggt
     5401 gcgcaaaatg ggtcatctgg ttatgatgta tttacgaaac aaccagaagt attaaaagag
     5461 atagtcaaaa accaagatgc tgttttgtat gatagtttta atgaagcatt gatcgatctg
     5521 aaaagcagac gggtcgatgg tctgctgatg gataaagtat acgcagacta ttatttgaaa
     5581 caaagaaacg aactagaaga cttcaacata acaaaaggtt cttatgagag tgaggatttt
     5641 gcagttggtg cacgcaagtc agatagtaca ttagtgaaaa aaatcaatga agccctagat
     5701 caactagaga aaacaggtga attccaaaaa atatccgata aatggtttgg cgaagatgtt
     5761 acgccgagaa attaacaaat aggggactgt gacaaaagac gtgtcacagt ccctttttcc
     5821 gaataaacag tgttctcctg ccaactcctt gtgactcgga gctgaatggc aggctcacaa
     5881 cctcttggta aacggtgttc aaaagccagt ttttcggtat taagccaaat ttatgcaaaa
     5941 atgtagaaag ccattttcac aaaatttttc ttactactcg aaactaagcg actttttcac
     6001 aacctccttt acataatttt attttgttgt ggaaggggtt tcgtgttatt ctaaaagagg
     6061 aacgattgaa ggttatagga aaggaagaga tgaatggaac acaaagaact tacctcattt
     6121 ccaaaagatt ttctgtgggg ctctgcttct gcagcgtatc aagtagaagg agcttggcaa
     6181 gaagatggga aaggagaatc agtctgggat cgatttgtac ggatacctgg aaagacattt
     6241 aaaggaacga acggtgattt ggcagtagac cactatcatc gttataaaga agatattgct
     6301 ttaatgaaag aacaaggtct gaaagcttac cgcttctctg tagcttggac acggattttt
     6361 cctaatggac gaggagaagt caatcaagct gggctcgctt tttatgagag attgatcgac
     6421 gaattgattg aaaacgatat tgaacctatg ttgactttat atcattggga tcttccacaa
     6481 gcattgcaag atgaatataa tggttgggaa tcacgtcaga tcattgaaga tttcactcat
     6541 tatgcagaaa cattatttga ggcattccgc gggaaagtcc attactggat tagtttgaat
     6601 gaacaaaata tcttcacttc attaggttat ttgttagcag cacatccgcc aggtgtgaca
     6661 gacccgaaac gaatgtatga agttaaccat attgctaatt tagcaaatgc atctgtcatc
     6721 aataaatttc acgagttaga aatgcctgga aaaatcggac caagctttgc gtatacgcca
     6781 aattatccaa ttgacagtaa tcctgaaaat gttctggctg ctgaaaatgc agaagacctg
     6841 atggccaatt attggatgga tgtctatatg tggggaaaat atccgattgc tgccatgagg
     6901 ttcttagaag aaaaaggatg ggcaccaacg attgaagctg gcgatgcaga attgctagaa
     6961 tctgctaaac cagattttct tgggatcaat tactatcaaa cggcgacgaa tgcattcaat
     7021 ccattaaacg gagttggtgc tggaaaaatg aatacgacag gaaaaaaagg ttcatcagaa
     7081 gaaactggag ttcctggaat gtataaaaaa gttgagaatc catttgtcga acgaacaaat
     7141 tgggactggg agattgaccc agaaggatta aggatcggac tgcgtcgtat cacaagccgt
     7201 taccgcatgc cggtactgat tacggaaaat ggcttaggag agtatgacaa gttgacagaa
     7261 gataaacaaa tccatgacga ctatcgaatc aattacttac aaagccacgt caaagccatc
     7321 aaagaagcaa tttcggatgg agcagaagtc ctaggctatt gcacctggtc ttatacagat
     7381 ttgcttagct ggctgaacgg ttatcaaaag cgatatggat ttgtatatgt tgatcaagac
     7441 gaaacacaag aaggatcttt ggaacgatat aagaaagaca gttattactg gtaccaaaaa
     7501 ctgattgaag aaaatggaga gaacctttag ttcacatact taaaacaaga aggtacggct
     7561 ggatatggcc gtgccttttc ttgataaaat catttagaaa ttaagaaaaa ctgtaaaata
     7621 agctgaaaaa tgaaagaaag cgtcagttct ttcaaacaaa actttagttc ccttactttt
     7681 ttttgtataa tgaaacttga tgaaatgagg gataataaat ggcacaaaag aaacggccta
     7741 ctaaaaaaag gaaaaagacg aaaaaaacga aaaagcaaaa acagcagcag gaacaaatgc
     7801 tgacgattgg tgttgggttt gccttgattt tatttgctgt cttcggcttt ttaaaattag
     7861 gttttttagg aatattgatt gcaaacggct ttcggatcat tgcaggaaat acttaccaaa
     7921 tcctctgtct tttattagcc gtattaggat tttggattgt cattaagaat acagagtttt
     7981 caattggtaa aaaccgacgc tggtttggcg gcatactctt ttatttcggt atcttattat
     8041 tgttacatgc ccatttattt ggcaaactcc atactgggga accaaatatc atggggacga
     8101 catgggattt gttagccagt gatataaaac aaagtcaagt agacaataac gttggtggtg
     8161 ggatgattgg agcaatcctt tatcatttta cttacttctt gattgcacag cctggaagtt
     8221 atttagcagc agtgctatta ctggcaggag gagcattcct gttcagtaat ctggaaggct
     8281 atcagctgtt aaatggtatc caatcaattg gagaacgagt acaggaatta ttggaaggtg
     8341 atcctgccaa gcaagctcga aagcaagcgg caaaggaaga gagaatgaaa cagcgcgcag
     8401 aagcgaaaga agcaaggcgc ttagctgcaa aagaagctgc agaaaaagaa gctgcagaat
     8461 atgagaagaa aaaagcggtg agccagcaaa gggaaaatac tgctgatgaa tggcaggaac
     8521 cagaaaatac agagccggag cagctaagtt ttgttccaat cgacagtttt caagaaaata
     8581 tccatcctgc gaatctagag aaaccagtac cagatacacc aaaacagacc aatacagcag
     8641 aaggtttttc agatgagttg ccagaggatg acggtacctc attagaattt gagattgaag
     8701 cagaacagga aaatcaagac tatgaattac cgacagttga tttgcttgat tctataccaa
     8761 ctgtggatca aagtgatgag tataaaaaaa ttgaaaaaaa tatcggcgta ttagaacaaa
     8821 ctttccaaag tttcggtgtc gatgccaagg tcgtcaaagc cagcttagga ccatccgtca
     8881 caaaattcga agtccagccg gctgtagggg taaaagtaag taaaattgtg aacttaacag
     8941 atgatatcgc gcttgcttta gcggcgaaag atgtccggat ggaagcaccg attccaggta
     9001 aatcactgat tggtattgaa gtaccaaatg gaaagatcag tatggtttcc tttagagaaa
     9061 tcatcgaagc acaaccaaac cacccagata aattactaga agtaccttta ggacgtgatg
     9121 tttctggacg ggtacaaacg gctgatcttt cgaagatgcc tcacttactc gtggctggtt
     9181 cgactggtag tgggaagtca gtagcaatta atgggattat cacaagtata ttaatgcgtg
     9241 ctaagcccca tgaagtaaaa ctgatgatga tcgatccgaa aatggttgaa ttgaatatgt
     9301 acaacggcat acctcatctg ttgacgccgg tcgtgacgaa ccctagaaaa gcagcgcaag
     9361 ccttacaaaa agtagtacaa gaaatggaag aacgatatga aaaattcgcg gcaaccggag
     9421 taagaaatat ttctggttac aatgaatttg ttcaacagaa aaacttggaa aacggaacga
     9481 aacatccaac cttaccattc atcgtagtga tcgtagatga attagctgat ttgatgatgg
     9541 tagccagcaa tgaagttgaa gatgcgatta ttcgtttagc gcaaatggct cgggcagcgg
     9601 ggattcatat gatcctagct actcaacgtc caagtgtgga tgttatcaca ggaatcatca
     9661 aagcaaatgt accttccaga atggcatttg cggtatcaag cggtacagat tctcggacga
     9721 tcattgattc taatggggca gaaaagctct tagggcgagg agatatgcta ttcttgccaa
     9781 tgggtgagaa taaaccgatc cgtgtgcaag gagcattcat ttctgaccac gaagtagaac
     9841 gggtcgttca atttgttaca gatcagcaag aagctcatta tgaagagaaa atgatgccga
     9901 cagatgaagt tgaaacgaca ggtgctccag aacagccaca agatgagctg tttgaagaag
     9961 caaaagcact tgtcgttgaa atgcaaacgg caagtatttc ccttctccaa agaagatttc
    10021 ggatcggtta caaccgagca gcacgtttag tagatgaact ggaagctcat ggagttgttg
    10081 gcccgtcaga aggaagcaag cctcggaaag tattcattga gcaggaagaa acatcagaaa
    10141 cgttgccgga cgataatgac atgtaaaact tgtgtgatga agggttgaaa aacgaataac
    10201 caataaaaag acaaggcatg atgataccaa aagaaaaaat ggtttttttc catcttttct
    10261 aatacggtat gatgtcttgt ctttttagtt tttgtgagat taaagttcta ttcgatttat
    10321 ttgtgaagta ttgcattaag gaaatgaatc atgtatagta tgtagcgaaa ctttgagaaa
    10381 aagagggaaa atactttgga aaaacagtcc atttatggct tgacgaatga agaattaatc
    10441 aattggttta tagaaaacgg cgagaaaaaa ttccgagctg cccaagtttg ggaatggttg
    10501 tatcaaaaac gtgtaagtaa tttcacagaa atgacgaatc tatcgaaaca attgatcgaa
    10561 aaattatcgg agcattttat catcaatcct ctaaaacaga tggtcgtcca agaagcttcg
    10621 gatggtacag taaaatattt gtttgaactc cctgataaaa acatgattga gactgtactg
    10681 atgagacaag aatatggctt gtcagtttgt gtgacgacac aagtaggatg taatatcggc
    10741 tgtacgtttt gtgcaagcgg gctgctcaaa aagaaccgtg atctgactgc tggagaaatt
    10801 gttgcacaga tcatgatggt ccaacattat tttgatgagc gcaatcttgg cgaacgcgtt
    10861 tcacatgtcg ttgtaatggg gatcggtgag ccatttgata attacgacaa tgtaatggac
    10921 tttttgcata tcatcaatga tgccaaagga ttggcaattg gtgctcggca cattacagtt
    10981 tccactagtg gattagcaca caaaatcaag gaattcgcta ataacggctt gcaagtcaat
    11041 ctggctattt ccttgcacgc gccgaataat gaggtgcgaa catcgatcat gcggatcaac
    11101 cgaagtttcc caattgagaa attgatggaa gctgtggatg agtatttaga gaaaacaaac
    11161 cgtcgaatca cgtttgaata tatcatgttg aatcaagtaa atgatagacc agagcatgcg
    11221 caacaattag cagatctatt aaaagataag aaaaaattag catatgtcaa cttgattcca
    11281 tataatccag tcagtgaaca tgatcaatat tctcgcagtc caaaagctga tgtattgaga
    11341 ttttatgatg tattgaagaa aaacggcgta aactgtgtga tacgtaaaga acatggtaca
    11401 gatattgatg cagcttgcgg acaattgcga agcaagcaaa tgaaaaaaac agttgccaaa
    11461 taatcgtatc ctactcgttt tttcaattac cataaaagga gcagttttct taattaagga
    11521 actgttcaac ttaaataaga gaaaagattc tatagcgaaa gctataaagc tttttttgac
    11581 aagaaaaacc ctcatcaagc aaagaaatgt cctcaatttg atgacagcct gcttgatggg
    11641 ggttttagca attatttaac tgattttctt atatccttgc tggctttctt gtgtagcatg
    11701 ataagtttct acgtcaagaa tggcctgttt aaatttttct cgggtgattt cataaggcac
    11761 atgtttaata tcatttgttg ccatggcttt atctaagatt gcttctaaat cggtcgtgac
    11821 attgagattc atgtcggtta acgatactgg aagttggttc tttttcataa acacatagat
    11881 tttatcaaac aaatcgaact gctgatccat catcaataag gtcagtacac cataactgac
    11941 agatgctccg tgaaggtatc cctccatttt ttctagaaca gtcgtaccgt aatagaatga
    12001 gtgtgccata gcagaattat agttattgtt aactaaaaca gaaaccaatc cggtagtaac
    12061 aatgatatcc gaaacgactt gttcaattgc atatgaggga cgatcgtcgg cactatcttt
    12121 caatgcttgc gtaccataag tcaagagacg atcaatgcac atttttccga tttggattcc
    12181 taatctatcc gtgtagccta gatcatcgcc acgagcagaa aaagtagatt cgacttcttt
    12241 ggataaagca tcgccaatac ctgcccataa gtatttatca ggtgcttcgg caataattgc
    12301 tgtatcaatg aaggtgtgta caggtggttt tgaaggaaag aagagtccgt ccattacgcc
    12361 ttcttcgtta tagatgacac ataccgcagt gacgggcgaa cagttcgaac caatagtggg
    12421 aaaggtgaag actggtttag ctagtttttc accaatgact tttacagtat cgcaagcacg
    12481 gccaccaccg actgcaaaca ggacgtctgc tttttggaca ctttcatgct ggatcaactg
    12541 ttcaatattt ccataagttg aattaccccc gtaccagaga ctggcgacaa cctctatttc
    12601 ctgtgtcaaa gctactttta ttttgttttc tgcctttgaa agtgcagtct tccctccaat
    12661 cagcactact tttgtcccat attctttgac gattccattt gctttttcat acgcatctgt
    12721 tccaatggta taatttggta agaaaacact ttgactcata ttcatttcct tctttcttcg
    12781 ttgaaacggg ttaaaatttt aaagagtgat cgatctgact gcggctgtag atggagtaga
    12841 ggtgaaccta agacaggata agtgatgaat aaggtggcat gaacaccttg aaatcatcaa
    12901 taagtatcct aaaaacgaac aagtacaaaa acattgaaaa cgacaataat gaatttttgt
    12961 tcctcttagt atttctaccg attccctttg cttttttgta attatctaaa aattctaaaa
    13021 attaagatta ttatatgaaa acaggtttta tttgtcaatt cataattggt tttttttaaa
    13081 gcaaaagata atctatatca tgatgaacaa acagagtttt ttcctccaat tgatggcttt
    13141 cctgatcttt cctattttga ataaagtgtt tctgtataat ttttttattt tataagtaag
    13201 ataaataatg aaagaataga gatactgatt ggtagctaaa gatttttgag cgagaacatt
    13261 tcgttttttc aaaaggactg ttagaataag caagaacaag ggggaagacg tatgataatc
    13321 agtgaatttg accgtaataa tccagtattg aaagatcagc tttctgattt actgagactg
    13381 acttggccgg aagaatatgg agacagctcg gcagaagaag tagaagaaat gatgaatcca
    13441 gaacgaatcg cggtagcagc ggtagaccaa gatgagttag taggatttat tggtgcaatc
    13501 cctcaatacg gtatcacagg ttgggaattg catccattag ttgtagaaag ctcccgacga
    13561 aagaaccaaa taggtactcg attagtcaat tacttagaaa aagaagtagc ttccagagga
    13621 ggaatcacga tttatttagg tacggatgat ttagaccatg gaacaacgtt aagtcaaacg
    13681 gacctgtatg agcatacatt tgataaagtg gcttccatcc agaaccttcg tgaacatccg
    13741 tatgaattct atgaaaaatt aggttataaa atcgtaggtg tcttaccaaa tgcaaatggc
    13801 tgggacaaac cggatatttg gatggcaaaa acgattattc ctcgaccaaa ttctcaataa
    13861 taaaaagagg ttgtgacaga agtaatcagc ttcaagaaat aagaaggaat ttacgaaaat
    13921 tacttcttga atttttgtga aattccaact tatttccgaa gaagctactt ttggaacacc
    13981 gtgtaccaga ggttgtgaaa aagtcgctag tttcgagtag taagaaaaat tttgtgaaaa
    14041 tggctttcta catttttgca taaatttggc ttaataccga gaaactggct tttgaacacc
    14101 gtttattcag ataagggact gtgacaagac ttttgtcaca gtttcttttt gtttattctt
    14161 ttttatcttt gtatggcaat aatagacaat ataacgaaaa ttatttaatg gcttttggaa
    14221 gaccatggaa aaccttgtac aaagctattt tttctgaaaa attccttgaa acctcacgaa
    14281 aaaatcatta ttttatgaaa aagacaaaaa aaagtgttga ttttttaata attattcatt
    14341 aaactcttaa acaacttcag aaaatattaa ttattctgaa aattccaata aaggggtacg
    14401 taaaatgaaa aagaaattta catttggttt ggttgcggta tgcggccttg tacttgctgg
    14461 atgttatggc ggcagttcag ccacaagcag tagttcagca aaaagcggtt cagcagatgg
    14521 aggaggcgta tttaacttag tcgtgcctca agaaatgcct acagctgact tatcagttgc
    14581 aacagataca atcagtttta cagcattgaa taacgtttat gaaggaattt accgtcttga
    14641 tgaagacagc aaaccacagc cggcaggagc tagcgagttg gcagaagtca gtgaagacgg
    14701 attaacttac aaaatcaaat tacgagaaga cgcaaaatgg tcaaatggtg atcctgttac
    14761 agcagcggat tacgtttatg gctggcaacg aacagtagac ccagctacag cttctgaata
    14821 tgcttacctg tatgcgccag ttgaaaatgc agaagacatt acagctggaa agaaagataa
    14881 atcagaacta gggatcaaag cagttggtga ctatgaatta gaaatcaaat tgacgaaaca
    14941 aacaccatat ttccaatatc tgcttgcttt cccatcattt ttcccacaaa aacaatccgt
    15001 agtggaagaa aatggggatg cctatgcatc tgcaagtgat aaagctgttt ataatggacc
    15061 attcacatta gaagattttg atggaccagg aacagataca gaatggactt ataagaaaaa
    15121 tgatcattac tgggacaaag atacagtaaa actttctgaa atcaaagtca gtgtagtaaa
    15181 agaatcttct actgcattga acttattcaa agatggccaa gcagatgacg tgatcttgtc
    15241 tggtgagtta gcacagcaaa acgcaaacga tccagcttat acttctgtta aagaagcgcg
    15301 gacaagctat atcgaattca atcaacgtga aaagaattca ccattcaaca atgtgaacct
    15361 aagaaaagct atttcttatt ctatcgatcg tgaagcttta gtaaaacaag tactaggtga
    15421 cggatcagtt gtctctacag gattgatccc atcagatatg gtaaaaagtc caacaacgaa
    15481 cgaagacttt gcaaaagaag ctggaaaatt agtttcttat gacaaagata aagcaaaaga
    15541 atattgggaa aaagcgaaaa aagaattggg cgttgattct ttagaatttg atttgatggc
    15601 ttctgatgat gattcatcga aaaaagtaat cgaatatgtt caaaactcaa tccaagaaaa
    15661 cttggatggc gtaacagtca aaccaacacc tgttccattc tctgtacgtc ttgaccgctc
    15721 aacttcgggt gattttgacg cagtactagg cggatgggct gctgactatg cagacccaag
    15781 cagctttact gatttgtttg tcacaggtaa ttcatacaac cgtggtcgct ggagcaatgc
    15841 agaatatgac gaagcagtta aagcagcttc atcaacagac gctggcgatg aacaagcccg
    15901 ttgggatgat ttccaaaaag caatcaagat catctctgat gatatgggtg tcgttccggt
    15961 gtaccaaaaa gcagaaggtc acctagtgaa tgaaaaaatc aaaggtatcg ttcaccatgc
    16021 ggcaggcgct tcatgggatt acaaatggac atacgttgaa gaataatcgt taataccgtg
    16081 agcatgagaa aaaacgaggc tgcggcaaat gtcgcaacct cgttctcata ttcacttatc
    16141 ctaacaaaga aaaaagcatg aaaatagcag aaagagcaat tagtattccg gcaatgatca
    16201 gccaaaagct gtacataccg tagctggcag acgagagcga ggaaaattct ggttttttct
    16261 ttcggttcct tgttcgtgca agatggaccg atcgctgaaa atgatcgaag aaacccgaag
    16321 aaaagaccca taaaaaaccg ccgataatca gaaacggcaa tgaccataag aatagatcat
    16381 tagataattg aatgagtgta aaggaatggt tgatgagatt ttttattaaa ataaccagaa
    16441 tcagtagaaa agctactgcg taggggatag attttttttt catttgattg ctcctttatt
    16501 tttggttcat tatctaataa tgtagcgaaa catctgtcag aagtcaaaag ctagggggaa
    16561 acattagtga atagttatat caaatatgta ttaaaacgtg tctttttcat gatcatcacg
    16621 ctttggttaa ttgcaacaat cacctttttc ttgatgcaat tgctgccggg cacgccatat
    16681 acgaatcagg aacgtttgag tcctgaaaca atcgagatgc taaataaaca agtcggtttg
    16741 gataaaccag ttatcgtaca atatgggatt tatctttcta atttgcttca aggagatttt
    16801 ggaatttcct tccaatttaa aaaccagcca gtcgcacatt tgttagctgg aagaatcgga
    16861 ccatccttgc agttagggtt acaggcaatt atctttggaa cagtcctagg gacgatttta
    16921 ggaacgatct ctgccatgaa gcaaaataca tgggcagata catcttctac actcgtagcg
    16981 atattaggtc gttccattcc aaactttgta tttgctgttt tattacaata tatctttgca
    17041 atcaaattac aagttttgcc aatcgcaaaa tgggatggct ttgtgtacac aatcttacca
    17101 acaattgcgt tggccatgtc gccgcttgct gactctgctc ggtttatccg tacggaaatg
    17161 gtggaagtac tgcatagtga ttatgtggaa ttagcaaaag caaaaggatt gagccgttgg
    17221 gaaatcgcct ttaaacatgg tcttcgaaat agtttgattc cattgatgac tttattagga
    17281 ccgttagctg tagcattgat gaccggatca ctggtggtag aaaatatctt tgctattcct
    17341 ggtatcgggg aacaattcgt taagtcaatc acaacaaatg attatcctac gatcatggct
    17401 gtaacgatcc tttactcatt tatgctgatt tttgttattt tgatcgtgga tctattgtac
    17461 ggtctagttg atccaagaat tcgtgtttca gaagggagcc gaggataaat ggaaatgata
    17521 ccaaagcgtt atgaaacagt tgcagatatc cctgcggatg aatttcttcc attacaaaaa
    17581 aataccgaag aagaacgtga acagattact gcaccttctt tgaattttat ccaagattca
    17641 tggcgccgtt taaagaaaaa caaagctgcc gttatttcaa tggttttact attggtcatc
    17701 attttgatct ctgtgatcac aatctttgtt tctcctcatg atccaactgc ccaaaacgtg
    17761 gcttatatca atttgcctcc tcgtattccg ggaatcaata tcgatggatt gaatggaaaa
    17821 gcaatggttg gtggtgaact tgttgataaa tatgctcaag caaacgtccc ttcaaacgta
    17881 aatttctttt taggaacaga cggtttggga cgtgatgtat taagccgctt atttatggga
    17941 atgagaatct cgttgctgat cgcatttatt gctgcattac tagatgtaac gattggtgta
    18001 gcttacgggt tggtttctgg tttgttaggc ggacgtgtcg ataacgtgat gcaacgtttt
    18061 ttggaaatct tatcaggaat tccaaacctc gttgtcatga ttttgatgtt ggtcgttttt
    18121 gaaccaggaa ttttttcaat cgtggctgct atggccatca caaactggat accaatggca
    18181 cgtatcgttc gtgcacaaac aatgaaatta aaagatcaag aatatgtttt agctggattg
    18241 acattaggtg aatcaagaat gaaaattgca ttcaaacata ttttgccgaa tatctctagt
    18301 gtcattatta ttcaaatgat gtttagtatt ccatctgcta ttttcttcga agccttttta
    18361 agctttatcg gtttaggtct tacgcctccg tcagcttcat taggaacgat gttgagcgaa
    18421 gggtacaaga cattcctgta tctgccttat ctattatgga ttccggcagt aactttatcg
    18481 gttatcatga ttggctttaa cttacttgct gatggattgc gtgatgcctt tgatcctaaa
    18541 atgaaagagt gaagacgatg acgaaaattt tagaagtgaa agacttagaa atctcttttg
    18601 atacgtatgc tggaaaggta cgagcgattc gcggtgtcaa ttttcatttg aataaaggag
    18661 aaacattggc gatcgttggg gaatctggaa gtggaaaatc agtgacgacc agaagcatca
    18721 tgcgcttgct gtcaagcaac gccaatatag atgctggtca aatcctcttt aaaggtaacg
    18781 atatcgttgg aaaatcagaa agagagatgc aaaaaatccg tggtaaagaa atagcgatga
    18841 ttttccaaga tccaatgacc tctttagatc cgacgatgcc cattgggaag caagtcgctg
    18901 agtcccttag aaagcataat aaagtttcaa aaaaagaggg acaaaaagct gcattagaat
    18961 tgcttaaatt agttggaata cccgaagctg agaaacgtat caacagttat ccgcatcagt
    19021 tctcaggagg tcagcgtcaa cggatcgtga tcgcgattgc actggtatgt tatccggaaa
    19081 tcctgattgc tgatgaacct acaacagcgc ttgatgtgac tattcaagca cagattttgg
    19141 agctgctgaa agaaattcag acaaaaatcg atacatcaat tatctttatc actcatgacc
    19201 ttggtgtagt agcgaatgtc gctgatcgtg tcgctgtcat gtatggagga agaatcgttg
    19261 aagttggaac atcggaagaa attttctaca acccgcaaca tccctatact tggggactgc
    19321 ttggttcaat gccgacatta gatagtgcga acgatcgatt gtatgctatt cctggttctc
    19381 caccggattt attgaacccg ccaaaaggag acgcattcta tccaagaaat gaattcgcga
    19441 tgaaaatcga tgcagaacaa gaaccaccat tttttgaact atcaaaaaca cacaaggcag
    19501 caacttggct acttgctccg caggcaccca aagtgacacc gccagaagaa atccaacgtc
    19561 gctgggctat ctttaaagag aaacaaaaac atacttacgg tcaaggagga attgctgatg
    19621 ccaaataaac tacttgaagt taaaggattg aaacagtatt tcaatgtagg aaaaaagaat
    19681 gaagtacatg ctgtaaatga catcagcttt cacatttatg aaggagaaac attcggttta
    19741 gttggagaat ctggaagcgg aaaatccact actggccgta cgatcattcg cttgaatgaa
    19801 cctactgatg gtgagatatt attcgacggt caagatataa cgaagatcaa agataaaaaa
    19861 ggtttgacga aattccggca tgatgttcag atgatctttc aagatccata cgcttcgttg
    19921 aatcctcgta tgaaagtcag agatatcatt gccgaaggaa ttgatgttaa tggactagct
    19981 aaatcatctg aagagcgtgc aaaaaaagtc gatgatctat tgagaactgt tggattgaat
    20041 ccaagccacg gtactcgtta tcctcatgaa ttttcaggtg ggcaacgcca gcgtattggt
    20101 attgcacgag cattggcagt aaaaccgcgt tttatcattt gtgatgaacc aatttctgca
    20161 ctagatgtgt cgatccaagc ccaagtggtc aatttgttgc aagatctcca aaaagaacat
    20221 caattgacct atctatttat tgcacatgat ttgtcgatgg ttaaacatat tagtgaccga
    20281 atcggtgtaa tgcataacgg cttgttatta gagatgggaa caagtgatga aatctataat
    20341 cacggtgttc atccttatac agaaagtttg ttatctgcta ttcctctacc agatccagac
    20401 catgagagaa aacgcagaag aatcaaatat caacctgaac cagatgacgg acaagtacgt
    20461 caacttcgtg aaatcgcacc agaacatttt gtctatgcaa ctgagcagga agtcccatat
    20521 tacgcaaaaa aactaaaacg acaaaaggaa tctcttctgg ttgctaacta ggagggacat
    20581 agatgctaaa agcttttaaa ttccgtatgt atccgacaga agaacaaaaa cagcaattga
    20641 ttcgtacttt tggatgtgct cgatttacct ataaccattt gctgaaaaag cggcagaaaa
    20701 gttggcaaca aacaggagta gccaattttt cgctcacacc cgctacatta aaaaaagaat
    20761 acccattctt aaaagaagta gacagtcttg ctttagcaaa tgcacagctt aatttggatc
    20821 gggcttttcg caattatttc aagggacgtg ccagcttccc aaagcttaaa acgaaaaaaa
    20881 gtatgtggca atcttatacg accaacaacc aaacccgtac gatctatctg gaaaatggct
    20941 acttaaagtt accaaaacaa aaagaactaa tcaagataaa tcagcatcgg ccagttgaag
    21001 gatcgattcg ctccgctacg atttctgctc gatataatga agaattttat gtcgcactac
    21061 tttgtgatgt ttcgccagta aaaaaagaat ctttagctaa atggatcggg atcgcctatc
    21121 atccgaagac attgatccaa acatctcgac ctctagaagt aactttacca aaatttcacc
    21181 agacagaaga aaagctgcaa catgcacagc ggaaattgaa tgtgaaagtc cgctccgctc
    21241 accatagaaa gatcaggtta gatcaggcaa gcaattatca gaaacaaaag agaaaagtaa
    21301 tggatcttta tctgaaacaa aagaaccagc gagaagatta tcttgaacaa ttatctggga
    21361 aattggtcaa acaatatgac tacttatttg tagaatcttt tccaaaagaa gaggcacatg
    21421 ctgatttttc tattcacgac tggcataaat taataacaaa attgcgttat aagtcccaat
    21481 ggtataataa aaaatttctt ttgatcaata ccgacggagc agaagaaagc aattccgtaa
    21541 gaaagagcca agtagtagaa aaaatgggca gacattcggt tatcaaggga taaaaaatga
    21601 atgaaactga taggagcgtt agggttagcc ttgttaataa aaagtcttaa tgacttttgt
    21661 ttctaggaat ttttcttttg aagaaaagct cactaattat gacaaaccaa taaaacaata
    21721 gcagaaaaag ttcgtacgag ctttttctgc tattgttaat tttttattca gaaagtttac
    21781 gaatacatca aaattctgaa acaaaaaacg taactcacaa agagttgttt ttgcgttttt
    21841 tcttgaatga ttaggtctga atcttttgct cacaacctta ttcatggtgc cccggcttga
    21901 gctgatagat ttttgaagga cggccgattc ctacaggacg ttcaccgatc tcatcgaaat
    21961 attggagcat agctttctta aaattggaat gatcgatcgt tttataatcg atccctaaga
    22021 atttagcaaa tacttttcga gcttccgtaa tcgtgaaatc tttacctaaa acttgtagaa
    22081 cttgcggctc gtgttccatt ttattgacta cacggttgaa tgctttcaag atgatttgac
    22141 tatggtcaaa agccaaagta tctttgccag aagactctcc agtgactaaa tcaagcgaga
    22201 tagccacttc tccgctagat aaatggatct tgttactatg acgttctagt gtgaaccagc
    22261 gtacttcctt ggcatcatct ccggcgatta gcggttcttc tccaataaag gctaagtagc
    22321 tgactgtgac gacccagcct cgcggatctc gattaggcgt actgaatgta tgcagttgct
    22381 caatattttc ttttgaaata accacaccag tttcttcctt tgtttctctt aagacgcttt
    22441 ctccagttga ctcatccttt tggacaaagc caccaggcaa tgcccatgaa tttcgataag
    22501 gatgcccttt tctttggatc aacaaaactt tcagctgatc ttcttctttg ttatagcaca
    22561 tcagtacgat atcgacagtc aaagagggct tgtcatattc tggacgttcc tgtttttgat
    22621 accagttaag aaattcttct tcacttgctt tatgttcata atataatttt tcttcttctt
    22681 tagaagcaaa acggttcatc tgaccacctc cattgacagt aaaagtactt tttaccttat
    22741 tgtagcagac tctgaaaaaa aaccaaggat ttacttgaaa aatctaggtt atcatttaaa
    22801 tatgaaaaat aaatggaagt atgagattga ataaaaagaa aagcagataa aacggcaata
    22861 ctttataccg ctcttcacga atggcaaaga agccacaaat aacgatatat acgtcaatga
    22921 taaaacgcaa aatccaagct gctgtcataa aactgttcaa atgcccatgg aggttaaaat
    22981 aaccatacat acgaatataa aaatagctga atattaaatg tgctaatgaa agaaaagcaa
    23041 tactaagtgt aaaaaaaaga tgtttcttct gcatgattgt tccagtccct tactaagata
    23101 gatagtcttt attataccac gtgtgagggg agaaataaaa agccgttttt tagtagatat
    23161 gaaacaaaac aaaaacccgc atttattcaa cctattcatc cttttaaagg atagattgaa
    23221 cgtagataga agtcgtttat ccagtctttt tcattttgaa aaaaagctaa cagcatgctt
    23281 tttttatggt atactagcaa ggaaacgaat tcgcatcatg cgataaagga ggaagagccc
    23341 cgtggcagaa aaggaaactt tttatatcac tacgccaatc tattatccaa gcggcaaact
    23401 tcatatcggc aactcgtata ctacgattgc atgtgacgca attgctcgtt ataaacggtt
    23461 gatgggcttt gatgtgtttt atctcactgg agtggatgaa catggtcaaa aaatcgaaac
    23521 aaaagcagaa gaactaggtg taaaaccgca agaatatgta gataaaatgg cggctgatgt
    23581 caagaaatta tggaaaacgc ttgatatcag ttatgataaa ttcattcgca cgacagatga
    23641 ttaccataaa gcagctgttc aaaaaatatt tgatcgttta ttagaacagg gagatattta
    23701 cttaggtgaa tatgaaggct ggtactctgt ttctgacgaa gaattcttta cagaaacaca
    23761 acttgcagaa gtgtacaaag atgacgaagg taacgtgatc ggtggtaaag cgccaagtgg
    23821 acacgaagta gaattggtaa aagaagaatc atacttcttc cgcatgagca aatacgcaga
    23881 ccgtctattg gaatactatg aagaacatcc cgaattcatc cagccagaat ctcgtaaaaa
    23941 cgaaatgatc aacaacttta tcaaaccagg attagaggat cttgcagttt cacgaacaac
    24001 ttttacttgg ggagtaccag tcaagagtga tccgaaacat gtggtgtatg tatggatcga
    24061 tgcattatcc aattatatta ctgcactagg atatggctcc gaagatgaaa gtctattcga
    24121 aaaatactgg cctgcagatg ttcagatggt cggtaaagaa atcgttcgct ttcatacgat
    24181 ctattggcca atcatgctga tggcccttga tttgcctcta cctaaaaaag tatttgggca
    24241 tggctggcta ttgatgaaag acggaaaaat gtctaaatca aaaggaaatg tcgtttatcc
    24301 tgaaatgctt gtggaacgtt atggtttaga tgcactccgt tattatttgc ttcgtgctgt
    24361 tccgtttggg tcagatggtg tctttacgcc agaagatttt gtttcccgtg tcaattatga
    24421 tctggcaaat gatctaggga acttattgaa tcgaacgatt gctatgatca acaaatattg
    24481 tgatggactc gttcctgact atgcctcact tgtcactcca tttgatagtg aactgtctac
    24541 gacggctgct aacgttgtcg gacgttacca tgatgcaatg gaaaaaatgg aattcaatac
    24601 agcattggct gaaatctggg tgctgatttc tcgtgcaaac aaatacattg atgaaacaga
    24661 accatgggta ttagcaaaag acgaagaaaa gaaagctgaa ttgaatagtg tcatgatcca
    24721 tttagctgaa tctttgcgta tcgcagcgat attacttcag ccaatcatga cagaaacgcc
    24781 agagaagatc ttcaatcaac taggattgga ctctgaaaca atgaatcttg aaggattaca
    24841 ctttggcgaa tttccttcag gaacaaaagt agttgcaaaa ggtacaccaa tcttcccacg
    24901 tttagatatg gaagaagaag ttgcttttat tcaagaaaaa atgtctgaag gtactcaaac
    24961 aaacgaagat acagtcaaat gggatccaga agaaacagaa cttgtttcaa cgaaagaaaa
    25021 acaaatcaaa tttgatgtat ttgaaaaagt agaactaaaa gtagcagaag tcatcaactg
    25081 tcaaaaagta gaaggggcag ataagttgct gcaattccga ctagatgctg gagacagcca
    25141 agaccgtcaa atcttgtcag gaatcgctga attttatcct gatccaagcg aattgatcgg
    25201 gaaaaaagtc gtcattgtag caaatctgaa accacgaaag atgcgtggac aaatcagtca
    25261 aggaatgatc ctttctgcag aagcaccaga tggctcttta caagtaatcg aagcaccaaa
    25321 atccatgcca aatggctcag aaatcgcata gaaattcaaa gggggtatga cactagttgt
    25381 gtcatacccc ctttttccga aatttgagaa gcaattttcg taaattcctt cttattactt
    25441 gaagccaatc atataataca gaaacagaga actatccaaa ataaatccta gaaaaagaag
    25501 tacgagcttc gctgattttt gttaatttag aataatacta ataggaatcg taaaaacaga
    25561 aaaaaagcat aatgataaag ggtcgggcag attttaattg attcatctgg tactcttttt
    25621 tattgtcctt acattcataa agtttgaatg caatgacttt attacatcta tatttatatc
    25681 taacagtagc gttgatgtgt taattataag ttctatcact ttatgttcaa ttagtttgtg
    25741 ctcttatatg tgtgattgaa aatatagata aaaaaacaat catcggcttt gacttcgatg
    25801 attgttttct ttattttgta aaaatcctat cacttgattt tatggtaacc ttttattttt
    25861 gtcttcaaac ggcttggtaa gagagcagta agcagtgcaa atgggatcga aaagacatac
    25921 cagaaaatcg tacgtccgat accataatgt tgatagagct ttgtcaacat cacgtgtaac
    25981 aagatcaacc ctaaaagcaa ggagccagct ataaaccaat gattatccca atgcatgact
    26041 tcactaagtg ccatcactcc aaaaggatag aaataaaaat agatcccgac taaggtcatc
    26101 cgccagttct ttgtaaatgt tccgatattc aataaaaaga aaatcgctga aagcaaaata
    26161 ccgataggcg gaaaaagccc aaccaaaaag gaatacaaca tcccccacaa gatcatcaca
    26221 ggacctttga tcaatgcaac gattgcgatg aacaaagtca gcaatattag tttttgtgat
    26281 aacgttgcaa cagtcattaa tccaaataaa attaatgtga accaatgcca atgggactgc
    26341 tgttgttctt tacgggaaaa atcgacccgg ttggataaat aatctgctaa tttcggataa
    26401 gaacgcttaa aatccataaa ctgttcctcc ttcgtggaaa aggtaggttt agtatacgaa
    26461 aaataaaaaa gaaatacatc cgtcttaaga gggagttttt cactgaaagt ggagaaaaaa
    26521 gaatggtaaa ttaaaatatt ctcagttata ctgaaaatta taccaaattt caaagaagaa
    26581 agaggatggg aatgaaaggc aaactaaaac gagaaatcaa tctgtttggc gcattagcta
    26641 ccgttatggg aaccgtgatc ggtgcaggcg tcttcttcaa aactgctgct gttactgcta
    26701 gtactcagtc tacaagtttg acattgctag cttggctttt gggtggtttc ttaacgatct
    26761 gtgctggatt gacagtggct gaattagcta cagcaatccc ggaaactggt ggagctgtaa
    26821 aatatattga agctgcgtat ggaaaattgc ccagcttttt attaggatgg gcgcaaagct
    26881 tgatttactt tcctgctaat attgctgcat tatcgattat ctttgcgaca caattgacga
    26941 acttattaca attatctacc gattatcttt tgttgattgc agtgatcacc gctgtttctg
    27001 tgacagggtt gaatttgtta gggacaaaag tcggtgcttc tgtacaatca gtgacgttga
    27061 ttgttaaatt aataccaatt gctgtgattg tcatatgggg attattgacc ccaggacaag
    27121 gaactgtcca gttatttcca atcgaagctg gaaaagatgt tacttttgtc gaaggattga
    27181 gcagtgcgtt gttagcaacg ttgtttgctt atgacggctg gttaggtgtc ggtgcaatgg
    27241 caggggaaat gaaacggccg gaaaaagatt tgcctaaagc aattattctt ggtttgagtt
    27301 ttgtaacagt cgtttatcta ttgatcaatt ttgttttttt gaaaactttg ccgattgatc
    27361 atcttgccgg taatttgaat gcagcttctg aagcatcaga cgtcattttt ggaggaatcg
    27421 gtggaaagct ggtcactatt gggatcttga tctcggtata cggtgcattg aacggttata
    27481 cactaactgg gatccgcgtg ccttatgcga tggctttaga agacgagcta cctttcagta
    27541 aacagctgac aaagctttca aagaagttta cggttcctta tgttcctgcg gttttccagt
    27601 tagcagtagc ttgtattatg atgagccttg gttctttcga ctttttaaca gacatgttga
    27661 tttttgtgat gtggctattc agtttactga tttttatcgg tgtctttatt ttaagaaaaa
    27721 aagcgccgga attgccacgt ccatataaag taccacttta tccaatcgtt ccgattattg
    27781 cgattctcgg tgctattttc attttaggta tgacgatgat gacgcaaacg aaattagcat
    27841 tgatcggtat aggtgttacc ttgataggta tcccagtcta ttatcaaaaa aagaaaaaac
    27901 gctcagaaga gtaaaatatt tcaacaacag acagaaaaag tacgaactag gtcctctaga
    27961 tcttcgtgct ttttctattt caataaaaca agttcttcta ttttgatttt tgctacttct
    28021 gcaagtagtg cttatgtgct aaagtaagaa tgaaaaggag agataaacat gatatttgat
    28081 tctcataccc atttaaatgc tgaacagttc aatgaagata ttccagaaac gattcagcga
    28141 gcacaagaaa tgggggtaac gaaaatggcg gtcgtgggct tcgatacgcc aacgattgaa
    28201 aagtctttgc aattaagcca tgactatcca aatatataca gtattatcgg ctggcatccg
    28261 acagaggctg gcagttatac gaaagaaatc gaaaataaat tacaagaaca attgacttta
    28321 ccaaaggttg tagcattagg ggaaattggc ttggattatc attggatgga agacccgaaa
    28381 gaagtccaag ataaagtatt tcgcagacag attgctatcg caaaagaaat gaacctacca
    28441 atcagtattc atactagaga agcacttgaa gacacgtatc aaatcctaaa agaagaagat
    28501 gttcgagata tcggtggaat catgcatagt ttcagtggtg attatgaatg ggcaaaacga
    28561 tttcttgact tagggatgca tatttcattt agcggtgtcg tcactttcaa aaaagcatta
    28621 gacgtccaag aggctgcagc aaatgtacca atcgaacgat tacttgtgga aacagatgcc
    28681 ccttatctgg caccagttcc ttttagagga aagcgaaatg aaccaggcta tactcgttat
    28741 acagtagaaa agattgctga acttcggaat cttccgacag aagaagtggc tgcccaaaca
    28801 tggacaaatg cgcaccgatt atttggtcta agcgaacatg gataagatga agatccaaga
    28861 gattatagtc gttgaaggaa aagacgatac aagaaggctg cgggaagtag ttgatgcaga
    28921 tacgatagaa acaatagggt ctgcaatcaa tgaagagatc ctgatgcaaa ttgaacatgc
    28981 ccaagagact cgtggagtga tcgtttttac cgatcctgat ttttcaggag aaaaaataag
    29041 aaaaatcatt atggaagctg ttcctcaggc aaaacatgct tttttgccgc gcacacaagc
    29101 taaaccaaag aaaaagggaa gccttggtgt cgagcatgca agtgatgctg ctattttaga
    29161 agcattgaaa aaggtcgtga cgccagacat ttcccaaacg gctgtttctg aaatcactag
    29221 acaagacctt ttagactatg gtttaatagc tggggcacaa gcaaaagaaa aacgagaaaa
    29281 actaggtgac gagttgcgca tcggttacac gaacggcaaa caattggaaa aacgtttgaa
    29341 gatgtttcgt attacgccga aagaactcgc ccaagcaatg aaaatagtgg aggaacaaca
    29401 tgagtgaata tcgtgaaatt gcgacaccct ctagaacaaa agagatttta ttgaaacatg
    29461 gtttttcatt taaaaaaagt ttaggacaaa attttctgac tgaaccaaat attttaagga
    29521 aaatcgtaga aactgcgcaa atagatgaac atacgaacgt gatcgaagtt ggaccaggaa
    29581 tcggtgcatt gacggaacaa ttagccaagc atgcaaaaca agtcgtagca tttgagatcg
    29641 atgatcgttt gatccctgta ttggctgata cgatgcaacc ctatgacaat gtgactattg
    29701 tacatcaaga tattttaaag accgatttgt caacagctgt tagagaaaca tttcatgagg
    29761 agcttccgtt aaaagtcgta gcgaatttac cttactatat tacgacaccg atcatgatgc
    29821 attttcttga atcagatttg gttgtggatg aactagtcgt catgatgcaa aaagaagtag
    29881 ctgatcgtat ctctgctgaa ccaggaacga aagcttatgg ttcattatcg attgctgttc
    29941 aatattatat ggaagccagt ttagcattca tcgtaccaaa aacagtattt gtccctcagc
    30001 caaatgtaga ttcagcgatt ttgaaactga caagaagaga tataccggca gtcgaagtga
    30061 cagacgaaaa agcatttttc cgattgacaa aagcggcatt tcagcaaaga agaaaaacgc
    30121 tttggaataa cttgcagcat tcgtatggca aagatgacca gacaaaagca tggttagcaa
    30181 aaagcttgga aacagctgga atcgatccaa aacgtcgtgg ggagactttg tcattacaag
    30241 aattcgccgc attaagcaat gcgatgtcag aaaatatgca gtaaaaaaag aggttgtgac
    30301 agaagttgtg aaaaagctgt cctgcatcaa gtaataagaa cagccaaaca aaaatagttc
    30361 ctcatgtttt tcgtttgttt gggcttatta ccgcagatgc aagcttttga acaccgttta
    30421 agaaagaggt tgtgggcctg ccgtttaact ctaagtcaca aggaacaatt tcaaaaaaca
    30481 gcttctcatg tttttgagtt agttggtctt attacttgat gcaagctctt gaccactatt
    30541 atgccgaaca aggagacgtg acacaaatgt tgtcgcatct cctatttttg tctcttgatc
    30601 aaaaaattct tatacttgat actcacactc attttgtatg gatttagaaa agaatatgtg
    30661 tcttgacagt tattagtaag tgagttatac taagtcgaca tttatgtgtc aagacatatt
    30721 aggagagaga aaaaatgaga aaaaattcag ttcgaaaact aacgatttct gctttattga
    30781 ttgggatggg ggtcattatc ccaatggtca tgcctaaaat catgattcca ccagcttcct
    30841 ttactttggc gtctcatgtg ccattattta ttgcgatgtt ttttacacca ggagttgcag
    30901 tggctgttgc gctaggtacg acatttggtt tctttttaac aacgccggtt atcatcgcat
    30961 tgcgagcatt gtcacatctt gtgtttgcgt tgattggggc ttggtacttg caaaagcatc
    31021 cgagtatcgt tttaaaaaat ggacagttta cttttgctaa ttggcgtttc caagggttca
    31081 attttgtgat cggtgtgatt cattctttag cagaaatgct agtagtcagc atcttttact
    31141 ttattggtaa tatgcctgaa acatattatt ctcaaggata tttttataca gtattcatct
    31201 tgatggggat tggtgggctc atccacagtt tagttgatta taatattgct tattttatag
    31261 caggaacact cagcaaatat tttgatatcc ccgtatttac ggcagcaaaa aaagaaaatc
    31321 ggaaagagtc ggttcaaggg tacgcgaaga aaacgacata ttagacatga tctctcaaaa
    31381 aaaaactctc atctagtaat ggataataaa tcctctaaga tgagagtttt ttgtcctaaa
    31441 aagagctgca ccaacatctt ctggcacagc tctaacaggg ggcaatttat ggaagtttga
    31501 tgacttgttc tgtttcttta tcaaagaagt ggcctttgct gatgttgaag gcaaggtcga
    31561 ctatttcgcc tggtttatgg aaatctcttg catctacttt tgagatgaac tcagtagaac
    31621 cagtttttgt gtaaagcatc gtttcagctc caagtaattc ggaaacgaca acttctgatt
    31681 tcactacggc ttcaggtgaa gcttcaaggg ctacttgttc actgtggatg tcttctggac
    31741 gaataccgaa gataacttct tttccttcat aacctttttc aactaatact ttgttttttc
    31801 cttcaggaat acgaagctta agcccatgtc catctgtgat aacaccattt ttcaatgtca
    31861 cattaaagaa gttcatggca ggagatccaa taaagccggc aacgaacata ttgacgggtg
    31921 tatcataaac ttctttcggt gtaccgattt gttggataaa tccgtctttc atgataacga
    31981 ttcggtcagc catagtcatt gcttctgtct gatcgtgagt aacatagatg gtcgttgttt
    32041 caagacgctg gtgaagtttg gcaatctcag cacgcatggc tacacgtaat ttagcatcta
    32101 aatttgataa tggctcatcc attaagaaga cttttgcatc ccgaacgatt gcccgtccca
    32161 atgccacacg ttggcgttgt ccaccagata aagcagctgg ttttcgtttc aagtattctg
    32221 tcagacctaa gatctctgct gcattgtcca cacgtttttt gatgtctgct ttatcatatt
    32281 tacgtaattt caagccaaaa gccatattat caaaaacagt catatgagga tacaatgcgt
    32341 agttttggaa aaccatggca atatcacggt ctttaggtgc cacgtcattc atgacttttc
    32401 cgccgatatt tagttctcct tcagagatat cttccagtcc cgcgatcatt cgcaaagtag
    32461 ttgactttcc acaaccggaa ggaccaacaa aaacgataaa ttcacggtct ttgattgata
    32521 gattaaaatc agttacagaa taattttctg cattgtcata ttttttatat acgtttttca
    32581 gagccatttc taccataata cgttccacac tttctttttt agttttatta actatttaaa
    32641 gtataaatga aagcgttaac taacttcaat gtcatgttga acaagaattt tttctttttt
    32701 ttgtcaatgt gctagtttta agctttaata aatatccata agaaataaaa actgatacac
    32761 tggagtaaat aagtatgtta acaatatcaa aaggagtgtc tcttatgaaa atcgctttga
    32821 tcgctcatga ccgaaaaaaa cctatgatgg tgaaattagc aacagcgtat aaaacaatat
    32881 tggaaaaaca tgaacttttt gctaccggga cgactgggca gaggatcacg gaagcaaccg
    32941 gcttgccgat ccatcggttt aaatccggac cgttaggcgg ggatcagcaa attggagcca
    33001 tgatttcgga ggatcagtta gatttggtga tttttcttcg agacccgctg gctgcacagc
    33061 cccatgaacc agatgtaaca gcacttatcc gtttatctga tgtctatgag attccgttag
    33121 ctacgaatat cggaacagct gaggtgctac taagaggact ggaagccggc ttcctagatt
    33181 ttcgaagaat cgtccatgaa atagacaagc atccactttc attttgatgg ataagcgtat
    33241 ggaaaaataa cgtttaatgt tcgcctatat gtagctataa aagctaaaca aactgataat
    33301 atgcgatata atacgaacgt attggataat ataaacaata atattagttt ttcgtatttg
    33361 cagtaaatgt gaaaatatgc tatagtttct gtgggaaaag atcccaaaaa taatacagag
    33421 tagaaaataa agcgttaagt gctaagagga tgggatgttg cctcttggac gaaggacgta
    33481 atgttcgcgg ttttattttc gcattcgctg catgatacga tgtagcagct cttaaaggag
    33541 atgctaaaaa tgaagaaaca ccggttagac gcacgtatga ttgctattat gggcttattg
    33601 attgcattga tggtcacttt gtcccgactg gtagcaatcg agaccccatt tattaaaatc
    33661 agtgtcacat ttattccaca agtgatcatg ggcattcttt ttggtccttt ttggtcaggg
    33721 ataggcgcag ttttagctga tttagtagga atggccctct tctcgaaatc tgcattcttt
    33781 attggattta cattgaatgc atttattgaa ggagcaatct acggattctt tttctatcga
    33841 aaagagatca cttggaaaaa tgccattctg gctacgctta gtgtcacgct gatcatcaac
    33901 ttatttttga caccattatg gcttgcgttg atgtaccatg tgccattgtt cagctgggtc
    33961 gtttgggcgc cccgcctgtt aaaaacagta atatggttac cgattcaatc aattgccatt
    34021 tattacgtag gacgtagtat tccttacaaa aaaattttaa gaagtttagc gatccacgct
    34081 aaataaaaaa caagcagtct tcccatccca gaagactgct tgtttttatt gtgctgtgaa
    34141 ttgtgcttga tagagccgtc ggtaataacc atctttttga agcagctcat catgggtgcc
    34201 catttcgaca atagctccct gatccatcac taatatctgg tccgcatttt tgattgtgga
    34261 caggcgatgg gcaatcacaa aactggtttt tccttccatc attgctaaga aggcttgttg
    34321 gatttttttc tctgtcaatg tatcgactga gctggtagct tcatctaaga tcaacatagg
    34381 gggattactg atcatcgttc gagcaatcgt caacagttgg cgttgtccat ctgatatctt
    34441 taacccttga ccgccaatct tagtatctaa tttttccggc aaacgttcta caaattcata
    34501 catataagag gcttttaggg catcattgat ttctgcgtca cttgcttccg gattcccaaa
    34561 acgaagattt tctcgcaatg tactgtcaaa tagccaagta tcttgtaaca ccattccaaa
    34621 acttttacgt aatgtatcac gttggataga gcggatgtca tggtcatcga ctgtaattgt
    34681 tccttttgtt gtgtcataaa aacgcatcag caaattaaca agtgtggatt ttccggcccc
    34741 tgtttttcct actatagcaa tggtttgacc tggataagca gtaaaattga aatcttcgat
    34801 caaacgctgc ttggggtcat aagaaaaaga aacatgatca aaagagactt ttcctttgat
    34861 atttttgggt tccaaggcat aggcatctgg caaatcaggc ttttcttctg gctgatcgat
    34921 caaatcaaat gctcgttcta gaccagaaaa agcggtttgc agttgtgtcg tgattccaga
    34981 aagttcgata aatggtttag aaaactgact tgagtagatc gtaaagctgg aaatcacacc
    35041 aacagtgatt gacgaaccac tcttcaatgc caataggccg ccaactaaac caatcgataa
    35101 ataagcaagg tgatctacaa aacgagaaga cgggtttgtc aaggaagaag aaaattgtgc
    35161 ccgttgtcct ttttcatata gatcagcatt tagcagttca aattgctgtt gactagcttc
    35221 ttcttgctga aaagctttca cgattttctg gttaccgatt cgttcggtca caaagcccga
    35281 gatatcccca ataatccttt gctgtctatc gaaatttgtt tgtgaagcac gagcaacgat
    35341 ccaactcaaa aggaaaataa ttggtgtaga acaaagaacg accaatgtca gaagtggact
    35401 tagacgcatc ataaaaataa acgaaagaat gatgattgcc actccagaaa ataattgatt
    35461 gaaggccgca gaaattgcaa tggaaatatt gtccatatca tttgtaaatc gactgacgat
    35521 atttccgtgg gagttttgat cataataacg aagtggcaat cgattcagat gagcaaatgc
    35581 atcttttctt aattttgcaa cggataagta agctaaccga ttgcttaaca cttggatgag
    35641 ccattgactg actacgttga ttaaaacgat accaccgaat agaataagta aatggaacag
    35701 tcgattgaag cggacctgtc cttctccaat catttgatcg atactttgac caatttgtaa
    35761 cgtcatcaca actgttgcaa tcccattgat gattcctagt atcacagcta gccaaatgtc
    35821 ttttgcatag gcagtaaggt aaggaatgaa tcggcggagc gtctgcaagg ataatttttt
    35881 tactttcata actattcttc ctcctgtgat gcgacgattt cctgatattc tgctgattga
    35941 gcaagtaatt cttcatgggt accctgagca gcaatcttac cttgatccat cactaagata
    36001 tgatgtgctt cttgaataga gcggacacgt tgggagataa taatcactgt actgccaaga
    36061 taagtctgta gcgccttacg caaatccaag tctgtttgat aatccaacgc acttaaagag
    36121 tcatctaaaa tcagtaatgc tggcttggca atcaaagctc ttgcaatcgt cagtcgctgt
    36181 ttttgtccgc cagagaaatt tttcccattt tccatgactt ttgtatctaa accatttgga
    36241 agctgacgga caaattcttc tgcctgagcg attttcagag cttcccaaca ttctttttct
    36301 gtggcgtctt tcttacccca ttgaaggttt tcacgaatag tcccggtaaa tagtacagaa
    36361 gtttggggaa caagagcaat ttgctgacgg agatgatcca gctgccaaga acgaacatcc
    36421 attccgtcca ttataactgt accggaactg acatcataga aacgcggaat caattgtgtc
    36481 aaagtcgttt tcccgcttcc ggttggacca atgattccaa ggactgtatt tcgcttcagc
    36541 tgaaatgtaa tattttggag agaaagacca gaatcaggag tataacggaa gtcaacatgg
    36601 tcaaaagcga taattgcttc agaagaaaaa tcgggagtag tactgacctc agcttcaaga
    36661 atcgaatttt ctgtgtctag cacctctttc acccgatttc ctgaagcttc ggcacgtgtg
    36721 aagatcacga cgaggtttga aacaacgatc agtgccaaaa gcatttgatt catataattg
    36781 atcaaagcaa gaacttgtcc ttgttgcaag ctaccaatat ttactttgat cccgccaact
    36841 gtcagcaaac agatgatccc gacattcatg atcaaggttg tagcaggtga taatagggca
    36901 gagatattgg aaacacgtaa ataattgttc gctagatcat ttgtgctttt atcgaacttc
    36961 tctgtttctt tttttgtctg cgcaaatgcg cggatgacac gaacaccgct aagattctga
    37021 ctaacgtgtt cattgagctg atctagtttt tcttgcactt tttggtagag aggaacggtt
    37081 tttttgatga taaaaaataa aatgattgag aaaataggca ataatgctaa gaaaaacaga
    37141 cctacttccc agtcgatcac aaaagccatg accactgacc cgatacttaa aaacggtgct
    37201 ctgatcaata aacgaatgac cattgctaaa gctagctgaa gctgattgat gtcgtttgtc
    37261 attcgggtga tcaaggtatc tgttccaaaa tgattcaact cgttgtgaga gaaagtattg
    37321 atttttttga ttagctgatt acgtaactct gtaccaaatc cttgtgaagc tactgaagca
    37381 tagtattggc aaatgatagc acaaatcaga ccaatcacag acatagcgac catccataag
    37441 cccatttcaa tgatttttcc tcggtcattc atttttagtc cattatcgat caaggaagcc
    37501 atcattaaag gcaggacaag ttcgaagaca gcttcaagaa atttgaagaa cgggcccaaa
    37561 atgatttgct tacgatagtc ttttgcataa cgtaataact gaatcatatg attcctccta
    37621 ttatttattt gtccacaatt gaaaaaacaa gtactaccac attgtagctt aggaaattta
    37681 gaatgaaaag agaacaagcc ttttcataaa tgaaagtttt attatgaaga agctttagaa
    37741 attgaataga ctattttttt taaaaaaaag aaa
//
LOCUS       DAZULR010000026        37136 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.026, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000026 DAZULR010000000
VERSION     DAZULR010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37136
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.026"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..730
                     /locus_tag="ACG8ZV_001518"
     CDS             <1..730
                     /locus_tag="ACG8ZV_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFS4996867.1"
                     /translation="NRLTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGA
                     DGKLAIDGLAPGVYQLVETQAPTGYELDATPIEFEIERSQTAVVELTKENRLTPGGVV
                     LTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGAYQLVETQAPT
                     GYELDATPVTFKIEKEQEVAIFLTKENRKVADSSDIRGNNPTSSGNKHLPKTGETIIS
                     QFILSILGVLLVFISIKFRKKRNI"
     gene            complement(1083..1931)
                     /locus_tag="ACG8ZV_001519"
                     /pseudo
     CDS             complement(1083..1931)
                     /locus_tag="ACG8ZV_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2084..3196
                     /locus_tag="ACG8ZV_001520"
     CDS             2084..3196
                     /locus_tag="ACG8ZV_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFS4996868.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            complement(3274..3567)
                     /locus_tag="ACG8ZV_001521"
     CDS             complement(3274..3567)
                     /locus_tag="ACG8ZV_001521"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase family
                     protein"
                     /protein_id="HFS4996869.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            3735..4049
                     /locus_tag="ACG8ZV_001522"
     CDS             3735..4049
                     /locus_tag="ACG8ZV_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HFS4996870.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            4070..6049
                     /locus_tag="ACG8ZV_001523"
     CDS             4070..6049
                     /locus_tag="ACG8ZV_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFS4996871.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            6062..6388
                     /locus_tag="ACG8ZV_001524"
     CDS             6062..6388
                     /locus_tag="ACG8ZV_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HFS4996872.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            6404..6922
                     /locus_tag="ACG8ZV_001525"
     CDS             6404..6922
                     /locus_tag="ACG8ZV_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996873.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            6922..8274
                     /gene="celB"
                     /locus_tag="ACG8ZV_001526"
     CDS             6922..8274
                     /gene="celB"
                     /locus_tag="ACG8ZV_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HFS4996874.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNSSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(8358..9863)
                     /locus_tag="ACG8ZV_001527"
     CDS             complement(8358..9863)
                     /locus_tag="ACG8ZV_001527"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HFS4996875.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLEFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(9955..10545)
                     /locus_tag="ACG8ZV_001528"
     CDS             complement(9955..10545)
                     /locus_tag="ACG8ZV_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFS4996876.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            10724..12370
                     /locus_tag="ACG8ZV_001529"
     CDS             10724..12370
                     /locus_tag="ACG8ZV_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFS4996877.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYFQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            12419..13138
                     /locus_tag="ACG8ZV_001530"
     CDS             12419..13138
                     /locus_tag="ACG8ZV_001530"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFS4996878.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            13617..14564
                     /locus_tag="ACG8ZV_001531"
     CDS             13617..14564
                     /locus_tag="ACG8ZV_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4996879.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            14576..15496
                     /locus_tag="ACG8ZV_001532"
     CDS             14576..15496
                     /locus_tag="ACG8ZV_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4996880.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            15537..16994
                     /locus_tag="ACG8ZV_001533"
     CDS             15537..16994
                     /locus_tag="ACG8ZV_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFS4996881.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            17339..17953
                     /locus_tag="ACG8ZV_001534"
     CDS             17339..17953
                     /locus_tag="ACG8ZV_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFS4996882.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            17946..19670
                     /locus_tag="ACG8ZV_001535"
     CDS             17946..19670
                     /locus_tag="ACG8ZV_001535"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFS4996883.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            19667..21118
                     /locus_tag="ACG8ZV_001536"
     CDS             19667..21118
                     /locus_tag="ACG8ZV_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFS4996884.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(21591..23744)
                     /locus_tag="ACG8ZV_001537"
     CDS             complement(21591..23744)
                     /locus_tag="ACG8ZV_001537"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HFS4996885.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDREYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(23746..24792)
                     /locus_tag="ACG8ZV_001538"
     CDS             complement(23746..24792)
                     /locus_tag="ACG8ZV_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFS4996886.1"
                     /translation="MTQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            24942..26231
                     /locus_tag="ACG8ZV_001539"
     CDS             24942..26231
                     /locus_tag="ACG8ZV_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HFS4996887.1"
                     /translation="MVYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDACRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            26244..28946
                     /locus_tag="ACG8ZV_001540"
     CDS             26244..28946
                     /locus_tag="ACG8ZV_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HFS4996888.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            28931..29788
                     /locus_tag="ACG8ZV_001541"
     CDS             28931..29788
                     /locus_tag="ACG8ZV_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFS4996889.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(29859..30716)
                     /locus_tag="ACG8ZV_001542"
     CDS             complement(29859..30716)
                     /locus_tag="ACG8ZV_001542"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFS4996890.1"
                     /translation="MKITITLPMNHPETTIRDLLEKEWLVPRKVRHFLRIRKNVWINQ
                     QPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDEHLIIVDKPAGMKTH
                     PNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKNPFVLPILGRMLEQK
                     MIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSALTHVTVNKVLSEQT
                     QVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHALELHMIHPFTQEKIV
                     GKALPGLWE"
     gene            30927..33098
                     /locus_tag="ACG8ZV_001543"
     CDS             30927..33098
                     /locus_tag="ACG8ZV_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HFS4996891.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPAVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            33166..33507
                     /locus_tag="ACG8ZV_001544"
     CDS             33166..33507
                     /locus_tag="ACG8ZV_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFS4996892.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(33783..35537)
                     /locus_tag="ACG8ZV_001545"
     CDS             complement(33783..35537)
                     /locus_tag="ACG8ZV_001545"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4996893.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLSFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQCISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(35548..36384)
                     /locus_tag="ACG8ZV_001546"
     CDS             complement(35548..36384)
                     /locus_tag="ACG8ZV_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFS4996894.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            complement(36386..37069)
                     /locus_tag="ACG8ZV_001547"
     CDS             complement(36386..37069)
                     /locus_tag="ACG8ZV_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HFS4996895.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLMPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
BASE COUNT        11976 a         6533 c         7607 g        11020 t
ORIGIN      
        1 aaaccgactt acaccaggcg gtgtcgtgtt gacaaagatc gatgaccaaa gcggggaagt
       61 cctgcaagga gctgtttttg agttacaaga tgccaatgga accgttctgc agtcaggtct
      121 aaccacagga gcagatggaa aactggcgat tgacggctta gcaccaggag tgtatcagct
      181 ggtagaaacc caagcgccaa cggggtatga attggatgcg acaccaatcg agtttgagat
      241 cgaaagaagt cagacagcgg tggtagaatt gacgaaagaa aatcgactta caccaggcgg
      301 tgtcgtgttg acaaagatcg atgaccaaag cggagaagtc ctgcaaggag ctgtttttga
      361 gttacaagat gccaatggaa ccgttctgca gtcaggtcta accacaggag cagatggaaa
      421 actggcgata gatggcttag caccaggagc atatcagctg gtagaaactc aagcgccaac
      481 ggggtatgaa ttggatgcga caccagtaac tttcaagatc gaaaaagaac aagaagtggc
      541 gatcttttta acaaaagaga atagaaaagt tgctgatagc tcagatataa gaggaaacaa
      601 tccaacaagc agtggaaata agcatcttcc aaaaactgga gaaaccatca ttagccagtt
      661 tatattgtca atattgggtg tgctacttgt tttcatcagt ataaaattta gaaagaaacg
      721 aaatatatga gctaaaataa aaaattgaat aagcatagtt tttaaaatca actagtaccc
      781 atcaattgaa tggaaactac cgattttaga aggggtatac aaacaaatat tagtatcgga
      841 gtagagaagg ttgaacccaa ccagtaaata agtaaagaca attttgtgct gcgttgagaa
      901 gtgaaaaata aacctttgta gtaatactag ttaataaaaa atatacaaaa acactgcgaa
      961 aatcattctt gagtttcgca gtgttttttg cctaatgact caagtttatt gggtaatact
     1021 ttgattttct ttctacaaat aatcagcgat cagttgtaat tttttctcta gttttaatgg
     1081 ctctttgtca ataaggagaa aaacaagtcg ggtcttttgt ctcggaaagc ttcaaccaac
     1141 tcgtgaataa aggttacgcc tccttgaaag gcgtggaaaa accaagtaat cgatcaatca
     1201 ccaatttcgc atttggtaga acatgtttgg tgagctgaaa gtaggtggcg ttcatgtctg
     1261 taactaagaa ttctatttct ttaggattag tgcagctaag gaaatagttt gttaatcgag
     1321 gaattttttg tgtaggtaaa ttttctcgat taatttttct gtctcgccat ccgcggaaat
     1381 aaaactcagt ttatcctcaa cggaaacgtg agaacgaaat tcacaaccct caacactcaa
     1441 gacagaattc ttttggaaga ctttggtaaa tagcttctca actctttcaa tgtgcgaata
     1501 acggttgtca aagataccta acaacttttc gaaataaaaa ataacgacac tttttcagtc
     1561 agtaaagaag tgattttatg tctgacatga tttgaaatcg agtgccttgg acggataaaa
     1621 taactttgag cgttccaatg gcttcgacag tttttacagg tatagcgctg cttttttagg
     1681 cgtataacca ttggcatatg attatattat tcaaagtgga caatggtttc cttcttcttg
     1741 tttttcacca ccattaattt cctatttcca tctaccacag cagaaccaca atttctacag
     1801 acacatggag cagggaagag aactgcagca acgatcaatg tttttttctt ctgtaaggtt
     1861 tcgtaagaga cctctgtaat catcaaattt ttgtctattg atctcagaat ttttttgata
     1921 gaaccattca taaagcatat cgttctctca gttgtttatt ttgtggtgat ttaatcatac
     1981 aagaaaacga tatgtttttt tataaaaaca tgaataggaa aaatagttga caagaaaatg
     2041 acaacgccat atgatgttcc atagtattta caacctgtca tagatgactg taaaaaataa
     2101 aagtaaaaag aaaggacgac aacaggtgga tttttatcag tctctacaac tagatccgtt
     2161 tattttaaaa caaaaaatac gagaagcagc ttctaaaaaa gaaaagtgca tgtatatttg
     2221 ttcattgttt ttacgatcat tattcatcgt attgtttgcc atttgtttta tcattataat
     2281 tacaacatta tttgaatcga agcataaacc atacgctgtg gttttattct gtatgttgat
     2341 gagtattcgt tttgttgact ttggttataa gatttcccat tcgatcatag gtttagcaat
     2401 cgtcatgttc tcactattag tagcaccgta tgtccagctg atcaaatggt cagttatggg
     2461 catgttgatt cattttattt tactaagcag catattaatg gcaaccgcta gtgatcccaa
     2521 aatggggaat gcttctttgt acggcttttc atatctcttt attgtttatt cgttacctaa
     2581 agattcgttg aacaagaatt tctttacaca aacaagtagc ttattatttt tgtttttttg
     2641 ttggttttca gttcttcttt acagaaaaca tcgagaaaag aacaaagaca aaagcttgtt
     2701 taaagagatt tttttgaaag gcatgtattc gcaggaaaaa atttggatgc tcatctatgc
     2761 atttggcatt agtcttttga tcgttgcagg agagtatgtc ccttttcagc gattgatgtg
     2821 ggcagggttt gcattttctt ctattgtatc tagctatgga ttgatgtcga ttggtttcaa
     2881 agaacgagca gtagaccgaa tcattggctc attgattgga tgtgttttat ttattggtat
     2941 cagccaattt attcctttta actgggtcgg tatattaggt ggtctagctt taggtgtttg
     3001 ttctacctat agatataaaa cagtttttaa ttcttttggt gctttggcaa tcactgccag
     3061 tttattcggg gttccaggag cagtaacgat ccgcattttt gagaatatcc ttggggtatg
     3121 tttaggaatc atgtatattg gggtgactga aatacttatc cgaaaaataa gagaaaaaca
     3181 cggtttgaat cattagatga gatcgaataa aaaataagga aaaagtgaag atacacatgg
     3241 atgataaatt gctatcattc catgtgtatc tttttacggt aaatcagtga aacgttcgac
     3301 tttcattttt aatttatact ttttacggag ttcgtttatt tgagccatca tttcggattt
     3361 gtgatgcttt tcgattgctt cttcatcttt ccaacggtcg atcagtaaaa gagattctgg
     3421 atcttctagt ggaaagtaat agtcatattt ctcgtttcct tcttctgcac gaatcgcttt
     3481 gacaatgttt ctttcgacca tttcttctgc aaattttctg gcttgtccat ttgtacttgt
     3541 atacaaaata ttcactgtga tactcactaa atcccctcct gaaaaaattc tatcactagt
     3601 atatcacggt gccagaaatt attattcaag atatgataca cattttttcc gcaatgctac
     3661 ggaaatatat attttgaata gaaaacgctt acaagatatg cttggtttat aaaaataaaa
     3721 ggagtgattg atttatgaaa aaagcattga ttatttgtgc ggcaggaatg tcatcctcga
     3781 tgatggcctc aaagacaacg gatttcttta agcaaaaaag agaagaggta ctcgtagatg
     3841 cagtttcagc tacagaaggc gataatatga ttaagaatag tgattttgat ttatttctga
     3901 tcagcccgca aacgacgatg tttttggata aattcaaaaa attaggagaa tctgttggaa
     3961 agcctgttgt tagtatccct ttccaagcgt atgtcccaat ccctacaggc atccagaagt
     4021 tagcagaggt gatcgaagag aacatatgat ggaataggag tggatgataa tgaaacagaa
     4081 ggaaaaattg ctgttgagat atttgattga tcacaagaag gagtatgtca ccagtcaacg
     4141 tttagcttct gaattgttat tatctgatcg gacaatccgt aattacttgc agcggatcaa
     4201 agagttagta gaaaaaaacg gaggtaagat cattgctaaa ccaggttatg gctaccaact
     4261 gcatatttta caaagactga catttgactt gtttttgagt cggcaagaaa tagtacctgg
     4321 atatgctaga gaaccgcaag gattttatga gtccgaagat cgacaaaagt atatattgaa
     4381 ccaattgctt ttggaagatg ccattctttt tatggatgat ttggcagaag agctttatat
     4441 cagtcgttcc agtttgacaa aggacatgca agaaatcaag gagcgattga ttccatattc
     4501 actaaaaatc gtttctaagc atggtcaagg gacatggatc gaaggggaag aaagaaatcg
     4561 acggcatttt atcatggata ctttttttgg aaaccattat ggaaattcat tgaaagaata
     4621 tttagggcaa agccgttttt tcccagacat cagttttgaa gagctagtca ttatcattct
     4681 cgatgaaaca agagaagcta agttaaaagt ttcggatttt atcatacaga atctgacttt
     4741 acacttggct ttggggatca aacggctccg agaagggttt gaaatcaagg aattaggcat
     4801 cgaacaagaa gtttctaagc gagtagagta tcaagtggcg cagcggatcg ttcaacgtat
     4861 tgaggtaatc gcaggtgtat cgtttcccga agaagaaatt gcttatttga cattacatct
     4921 catggctaag tcgaatcaca aagaaaatca aaatgatcag gaactatcaa aggaattagc
     4981 gaaagttctg aaaagattgt ctcaggaatt tcatttttca ttagtagagg atctccagct
     5041 tttcaatgga ctactcgatc atttgtcacc gatgatgatt cgattgagcc gaggtattcg
     5101 cattgagaac ccattgactg aggagataaa gaaagaaaat cccaaagtct ttgacgcagt
     5161 aaaaaggcat ttcagcaaca tgccggcttt gaaaaactat accatcaatg aagatgaatg
     5221 ggcctatttg gctttgcatc tcatggcggc attggaaaaa gaaagagctg cgcataaact
     5281 acatgcattg attatctgtg caacgggtta cggcagtgcc caactattaa agaatcgcgt
     5341 agtcagtgaa ttcggtaaaa atattacagt ggtaagtgta aaaggctatt atgagatcaa
     5401 tgaaacaact ttaaaaggaa tcgacctgat tatttcttct attgatcttt cgacaatgtt
     5461 tttcaaaatt ccagttttac atgtcagtat ttttttgaat gaagatgatg ttcgtaaaat
     5521 acgaaaggta gttggagaat ctatacccta tcattcctca gatagaccga taccagcatt
     5581 ttctctacag caaaaaaagc agatttacac cgaacagttg tctgaaaaat ttttcaagac
     5641 ttatacgtac gaaccgaaaa aggaagaaat tcttcatgat ttgctgcaaa agctgagcat
     5701 aaatgaagaa gaaggatata taagagaaat gcgaaagcag atccagcaac gtgaaaatat
     5761 gggacaaatc atattcagtg atacagtggc agtcccacat cccgctgttc cagttggaat
     5821 cgaaacaaag gtagccgttg cattgattcc ttctgggatg cagtgggatc aatatcaaga
     5881 aattcatttt gtttttttag tttcgccttc ttatgtcgaa aatgaaggaa ttacggtcgt
     5941 gactaaagca atcgttaggt tagttgacca gctaaaagta cagcaggaaa tcttagctga
     6001 acctattttt gagaatttca gcagtaaatt tatcaaactg atcgaataag gaggaaaaca
     6061 gatggctgaa aaaataaaca gtgaaacact acaagtgact tcttttgata tcattttcca
     6121 tagcggaaat gcacggacac tgatacatga agcatttcgc tcgatgcgta aagagatgtt
     6181 tgaagaagta gaagagaagt tgcgacaagc aaatgaagag attcttcatg cgcatcagtc
     6241 acaaactcaa cttctgaaag aatatgccag cgggacaaaa atagaaatgg aaattatcat
     6301 ggtccatgca caagatcatc tgatgacgac gatgacatta ttggaagttg cacaggaaat
     6361 gaattatttg tatcaaaaaa ataaatagaa aggaaggatc attgtgcagg atacagtaaa
     6421 aaggaaaatc gaattagaaa aaaagcaact tagtttgaaa aacatgtatt tcaatcgtta
     6481 tctaatcgta cgttacctga ctgccttttt ctttttcatg aacatgcaat ggatgattct
     6541 gcttctatca gctaaaagtt taggaagtag tttaccgatg attctgattt tagctatttt
     6601 gcctgcagta ggagaacaag taaagcttta tcgaaaacac caaacgaacg ttccatggac
     6661 aaagtggtat tttttgttcc agagtgtctt taatttatta gtgattccag tgttgtttac
     6721 ctcaggattt acattcttgt atccttttat ggcaaataac aatggaggac agttatttgt
     6781 tttcattctt gttgtaagcg gtatttttgc cagtgcattt atacagtatc gtttaaagaa
     6841 aatttcactc aaccaagacc aacagtatat ccgtattaaa caatatgaaa aagcgttata
     6901 tttaggaaag gagaataact aatgtttgat tttttgcaga aatacctgat gggacctatg
     6961 gggaaaattg cgcaacttaa aatcgttcgg gctgtcatgg cagcggggat ggcttctatt
     7021 cctttcacga ttgtaggctc gatgtttttg gttttaaata ttttgccatt accgttccca
     7081 tttttagaag gattttttaa tgcaactttt ttcaaagtta gtgacttgta catgatcgtc
     7141 aatacaatga cgatggggat tttatctatt tactttgcca ttgtgtttgc ttatgaatta
     7201 acgtcaattg aacgagatga acaaaaatta aatgttaatc cgctcacggg ggcattacta
     7261 tctgtttttg cattctttat gtgtatccct gaattgatca tgactgatgg taaaatcagc
     7321 ttgattgctt ctatcaatga gacagaaact gtagtaaatg gtattaggat gggctctttt
     7381 gtcgaacgtt taggaacttc aggaatcttt acagctatta ttatgtcgat tattgcggtc
     7441 gaattgtatt gtatgtgtgt caagagaaat tgggtcataa aaatgccaga tgttgttccg
     7501 ccaggagttt ctcgttcttt cactgctctg atcccaacat ttgtcattgc gtttgtggtg
     7561 atgatcatca atggattatt agttgcacta ggaacggata tcttcaaaat gattgctatc
     7621 ccatttgggt ttgttacgca gttgacgaat acatggcttg gtgtcatggt gatttatttc
     7681 ttgatccatg cattgtggat cgtagggatc catggagcga atatcatcac ttctttcttg
     7741 accccgatcg tattagctaa tatggcagct aacgcacaag gcgcaaatta tccgttggca
     7801 ggagaattca acagttctta tgtaaccgtt ggtggatcag gtgcgacttt aggattgatc
     7861 atctttattg cattcctcgc gaaatctgat cagctgaaag tgttaggaaa agcctcactt
     7921 gtaccaggat tattcaatat caatgaacca atcattttcg ggatgccaat cgtctacaat
     7981 ccctatttag cggttccgtt tttcttagct ccgatggctt ctgctacact cgcttatttt
     8041 gccattcggc tggaaatcgt caaaccgatg cttgcacaga tgccgtggcc ttcaccagtc
     8101 gggatcggag catttgttgg tagtggtggt gattggaaag ctgctgtgtt agcagtcatt
     8161 tgtgcaatca tcgcattcat tatctggttc ccatttatca aattctatga taataaatta
     8221 ttaaatgaag aaagagaaaa ggcagcagaa ttagctagtg aaaagttaaa atgatttcta
     8281 agaaaaaagg aactgtgaca aaaaatcaca gtcccttttt ttcttagaaa tgggaaacca
     8341 ctagtatata aataccatta ttcttcaatc aaccgcttca cgattgcata atccccttca
     8401 taaggttcat ctacaccatt gattttttga tagggatcca cgccttttcc cgcaataacg
     8461 actgaatctt gcggagcgct ttctgctaaa gcgcgtcgaa tcgcttcagg acgatccatt
     8521 tcataatgaa cgatcaaatc tggattagta attgcttcat tgatttcttc cgcgattttt
     8581 ttcggatctt caaatgctgg gtcatctgcc gtcaaaaagg cgatgtcagc tgtttctgat
     8641 agcacttttc caaaatcatg tcgacgggag attgctttgt ttcctgggct gcctaataca
     8701 acaattacac ggccatctgg atgttcattt ttggcaaatt ccagcaatgt tttcaagctt
     8761 agataattat gtgcatagtc cacatagaca tgcgctccat tggattggat caattgatcc
     8821 attcggcctg gtacacgagc ttcttttaat ccgtcttgtg catcttgact ggaggcacct
     8881 gttagtgctg cggcaatgat cgcactggct gcattttctt ggttgaatcc tccagccagc
     8941 aaaatatcat aagcagtatc gcagatagct aagcgatctt catgagaaga taaagtaaaa
     9001 ccgtgagtac ctttatctga acggatcact tgataattgc tttcttccga acgaccataa
     9061 gtgatcgttg gaatctggaa tagatcggct gtttccctaa gtaaatcaaa atagtcactt
     9121 tcatgattta aaacaactgt ttttgaattc aagatcaatt gtcgcttgca atagaaatag
     9181 tcatcaaatg tcggatgttc gatcggactg atatggtcag gcgagatatt caagaagatt
     9241 ccgacatcta aagtcaagcc gtatacgcgt tgtgttttgt aagcttgtga agaaacttcc
     9301 atcactagat gagtcatacc attttcaact gcttctgaca tcatacgata taaatctaat
     9361 gactcaggcg ttgtcaaatg ggatttgaaa tatgttttgc catctaacgt tgtattcata
     9421 gtagaaagca atgctgtttt tttatttgtt gtgtgatcca agattgcttt tgtaaagtac
     9481 gcagcagttg ttttaccttt tgttccagtg aatccgatca ctttcaattt attttgcgga
     9541 tagtcgtaaa aagccatagc aagaagcgcc attgctttac ggatatccgt tacgatgatt
     9601 cctactgctg aattttcgta tggttgttct gatacataat attgaatacc ctgttcgatt
     9661 gctgaatcca aatattcttc tttgaaattc attcctttac agaaaaacaa agtagaagca
     9721 tcagcttttc ttgaatcata acttaactga agaaattcag ctttttctgg tacatcaaga
     9781 tgccagcctc ttgttgaaac aaattctttt aatagatttt cttttaatag taaatgacgg
     9841 atgtcttcta aagagaagct cattgattga tccctcgctt tattcaattt cttggtttat
     9901 tatagcacac tctttttaat atatcgtttg tttccgctat gacaaaatcc agctttattc
     9961 aaattttctt gacacagggg acaagcggat gagtattttc ataaacaatg aactgactgt
    10021 aatagatagg agaacgaata gtgtctccaa caatccaaaa acataataat tcaaaaagac
    10081 gataagacta ttggtaagta aaagtccttg cggcattgga agccgaaaaa atttgtggaa
    10141 aataatcggc ggtatcgtta taccgccatt tgaggccccg actgtgtaca atgtgtaaac
    10201 cccaagactg aacaaaagac ttcctgaaat cagtgaaaag aaatgtgagg agatcatttc
    10261 cacttttgga acaatctcta aaacaacagg aaaaagcaga cttcccgcta cagtcttaaa
    10321 aaatactgat tttcctaata ggacagcggc tagaagcagc atcataagat tgatgctcca
    10381 aacagtaact gagcgttgga tagaaaaggc cgtttcaact aaatgtccga tggcgcccac
    10441 tccggcggaa gctatatcgt gagggagcaa gaaccaattc aatccaactg tgataaagaa
    10501 aagacctaaa aatataacgg gtagtttttt tatttcttgt gtcattgata tctcctataa
    10561 atgttagcca taaaaggctg tatatttctt tactttacca aaaaaacgaa accgaattca
    10621 aaaaaacaat tgttcttata aaagttatat aaaatcgatt gccagtttct gttttaccaa
    10681 ttaaaatgat agtaatgttt tgtagaaagt tggaatctga ccgatggata atcaaagaaa
    10741 accagcatta gatcaattaa caccgcaaga aaaaatggca cgaggctctg cttggatgac
    10801 cgccagtaat atcatttcaa gattgctagg cgctgtctat atcattccct ggtatgcttg
    10861 gatgggcgaa aatgctaagg ctgccaatgg attattcaat atgggataca atatatatgc
    10921 attgtttcta ctgatctcta cagcaggaat acctgctgcg attgcaaaac aaactgcacg
    10981 ctataattca ttgaatgaat atggcacttc acgacgatta tttatccgtg cattacagat
    11041 gatgggcggg ctaggcctgt tgtttgcttt gttcatgtac atcgcctctc cttggctagc
    11101 tcatgcttct ggtggcggag aagaactgat tccaacgatg cgttctttga gtatcgctgt
    11161 attggttttt ccttgtatga gtgtgatacg agggtatttt caaggcaatc aagaaatgat
    11221 gccttatgcg ctgtcgcaga ttgtagaaca ggtggcacgt attttttata tgctattggc
    11281 tacattcatc atcatgaaag tcatggatgg tgactatgtg acggcggtca cgcaatcaac
    11341 tttcgcggca tttatcggta tgctagcaag tattcttgtc cttttgtatt ttttgaagaa
    11401 acatcaagcg tatacatcgg cgtttattca ctacagcgaa aacaaaataa atattgcaac
    11461 gaaggaattg ttgttagata ccgttaaaga agcgattccg tttattattg tgggttcagg
    11521 ggtaacgatc ttcaaattag tcgatcagtt cacttttatg aagatcatgt ctgcatccac
    11581 cgagtattcc aatgcacagt tactggatct tttttcgatt tttagtgcca atccagataa
    11641 gttgacgatg gtagttattg cattggcaac atcgatcgcg tctactgggt taccgttgat
    11701 tacagaagct gttacgttga aagatcgagt aggtctggca aaattgacaa gcggaaattt
    11761 acagttgttt tcatttttta tgtttccggc gacatttggt gttatgttac ttgcctatcc
    11821 gctaaataca ttattttata caccggattc tctaggaagt aatgtactga tccaagcaag
    11881 ttttgtagga ctcttcctag gactatatat gctagtttcc aacatgctgc aaggaatgtt
    11941 tgaaaacaag gcggcaatta attatttggt tattgggttt ctagtgaaac tccttcttca
    12001 atacccagcc attcgtttat ttgaagtata cggcccttta ttggcgacaa tgatcggatt
    12061 tgctgtgtct tgtaccttga tcttaaagag aatccatgaa gtagcccgct ttaaaccaag
    12121 ttttgtctgg cgcaggacat tgctgatctt tattcttacc ttgattatgc ttttggcttc
    12181 gtggatcaca aagatgattt ttggtgcttt tttaaacgaa gatagcaaat tccagtctct
    12241 attgttgatt cttgtagtag caggtatagg ggctttagtg tatggttatt tagctttgaa
    12301 aatccgcttg gcagaaagac tactaggacc aggaatagcg cgtttacgac ataaattaaa
    12361 aataaaataa gtgaatcaga agagctagat tgatgctctt ttgaaatggg ggaaacgcat
    12421 gcgtttagat aagtttttag cagatatggg acttggcagc cgcaaagaag tcaaaggatt
    12481 gatcaaaaaa ggaacgatcg aagtcaatgg acaagtggtg aaaagcgata aagcgcaagt
    12541 aaatgaattc gaagatgcgg ttacttattt aggagaaatc attacgtatc aaaaagattt
    12601 ttactacatt ttgcataaac ctgcaggagt catttctgct actcaggata atcatgatca
    12661 aaccgtaatc gatttattgg aagaccagga ttatcgggaa gatctttttc cagtcggccg
    12721 attagataaa gacacagagg gcctcttgat tttaacgaat gacggggtgt ttgcccatca
    12781 gttactatca cctaaaaaac atgtggagaa agaatatcta gctgaggtta gcggtataat
    12841 gacagaagaa gatatccgtt tatttgcaga aggactgatt attgatggcg atgagcagac
    12901 attgccggca aaactccaaa ttgatcaagt agatcaagag acagaaactt caattatccg
    12961 tctgattttg catgaaggaa agtttcacca agttaagcga atggtcaaag cagtaggaaa
    13021 agaagtctta tatttaaaaa gaatccgtat gggaaaattt tggctgccta aagatttgaa
    13081 taaagggcaa tatcgaccca tgaccaaaga agagctagaa caagtgagag aaaaataatt
    13141 gaatggatag ctaaaagaat aagcagagta gttgtagcgc catctgaaaa gcagacttgt
    13201 ccgtctgact ttcggatggc ttttttgtga aatttcggct tatttccgta gaagctactt
    13261 ctggaacacc gtttgttcgg aataagggac tgtgacaaga cttttgttac agtccccatt
    13321 gttccttgtg actcagagtt agatagtaag gacacgatct ccctaatact caggccaaaa
    13381 cgctgaattc acaacctctg ataaacggtg ttcaatcagc tgaccctcgg tattagctca
    13441 aaaaacggca aaatatgagg aactattttc ccgttttttt ctctaatact caggccaaaa
    13501 cgctgatttc acaacctctc ctatactttg tttcattttc cctatacttt gtttatttat
    13561 tctcattatt gaaagcgcta taattacgtt gcgaatgaat cgaaaggggt ttttagatga
    13621 aaaaacgaaa ggggttcaat cattttttta tgaatctatg gcgttataaa gcacttgtcc
    13681 tgatggctgt accgggtatg ctttggatga tttttttctt ttacatacct gtaatggcga
    13741 atgtcgtagc attcaaaaat tttcatattt cagcagatgg gttcttggct agcttgaggg
    13801 aaagtccttg ggtgggttgg gaaaatttca aatttttatt ttcttcggat caagcatttc
    13861 tcatcactaa aaatacaatt ttatataatg tagcatttat ccttttgaat ctgctgatct
    13921 cagtcgtatt tgcaatcatt atgagcgagt tgagaaataa acgactcgtt aaagtttatc
    13981 aaacgatgtc cttactacct tattttctat cttgggtcat tatcagttac tttgtttacg
    14041 cttttttaag tcctgacaaa ggaatattca atcagtggat cactggacat ggaggagaag
    14101 ctgtcaattg gtataatgaa ccgaaatatt ggccgtttat cttggtgttc attggtacat
    14161 ggaaagggat tggttataac agcattattt actttgcatc tgttatggga atcgatccga
    14221 cttattatga agctgctatg gttgatggag ctagcaaatg gcagcagatc aaacatgtga
    14281 cgataccaca acttattcca ctaatgacga ttttaacgat tttagccgta ggaaacattt
    14341 tccgagctga ttttggcctg ttttataaca ttcctaggaa ttccggtgca ttatatgatg
    14401 tgactcaagt tttggatacg tatatctaca atggcctgac atccacagga gattttggta
    14461 tgacggctgc tgcaggactt taccaatcag ttgtcggctt tgtcttgttg atgatcacaa
    14521 atacgatcgc ccgacgtttt gatagcgatt ctgcattatt ctaaggagga aaaaaatgaa
    14581 aaaaaagaaa gtggagagag tccaagtccg ctctttcaat aagacggcta attttttctc
    14641 taatataatg attgcactct ttgctatttc ctgtattttg ccatttatat ttgttatcgc
    14701 catctctttt accgatgagt ccatattgtc gactcacggg tacagttttt ggccagaaaa
    14761 gttcagtata tttggttata cgtacttgtt cgaccagatg caggataaaa ttttccaagc
    14821 gcttttcgtc actgtacttg ttactgtttt aggtacactg atcaatagca cggctacttc
    14881 tttatatgct tatgcgattt cacggtcaaa ctttccattc cgtcgttttt ttaccgtttt
    14941 ttgtttgatt acgatgttgt tctcaccagg gatggtggcc aattatcttg ttatgacaaa
    15001 tcttcttcag ttaaaagata cgatttgggc attgatcttg ccaatggctg tcagtccctt
    15061 caatattatt gtgatgcgca cattctttaa acgttcggtc tctgattcga ttattgaatc
    15121 ggcacggatc gatggagcta gcgaactgcg aatatttgtt cagatcgttt taccgttagc
    15181 tgttccaggt attgcgacaa tcagtttatt tgccgcattg ggttactgga atgactggtt
    15241 caatgcttta ctatacatcc aagatgataa gctagttcca ctacagtatc ttttgatgaa
    15301 aatccaaagt aatattcaat atctgacaca aaattcagga gcaggaagcc aattgacagg
    15361 cggattagcc tcagttccag gagaatctgc cagaatggcg atcgtagtca tctcgacgtt
    15421 gcctattgcg atcagctatc catttttcca gaagcatttt gtcaaaggtc taacaatcgg
    15481 cggagtaaaa gaataaagaa acaaaaatat aaatcataaa attaggagga agaaaaatga
    15541 agttatggaa gaaactagcc tttacaggtg tttcagcgtt gttgttggga acattagcag
    15601 catgcggagg ttctggttct aaagaccagg cagaagctag caattcggac actttgcaga
    15661 tgtatcaaat cggagataaa ccagataatt tcgatcaatt gatggaagta gcaaacaaac
    15721 gaatcgaaaa agagatcggt gtaaaagtca atatcaatta cattggctgg ggcgattacg
    15781 aaaagaaaat gaacgtcatc atttcttccg gggaaaatta tgatatcgcc tttgcgaaca
    15841 actatgtttc caatgcccaa aaaggagcct ttgctgattt gactgaatta gcgcctaagt
    15901 acgctgaaaa agcttataat gatttagatg aagcatatat taaaggaaat ctggtcaatg
    15961 gaaaattata tgctttccca gtcaatggaa atgtctttgc tcaacaagta cttactttta
    16021 acaaagcttt actagataaa tacgatcttt caattgatgg aatccaatct tacgctgatg
    16081 cagaaaaagt cttgaaggaa ttccatgaaa aagaaccaaa cacggcagct tttgccattg
    16141 gacaaggctt caaagtccaa gggaactttg attatccttt agggaatacg ttaccatttg
    16201 ctattgatct ggatggagat gattcgaaaa tcatcaacca atacgataat gaaacgtata
    16261 tcggactgtt acgtacaatg catagctggt acaaacaagg actcattcca agtgacgctg
    16321 caacgagcaa taaggattat ccactagaag gaaatacttg gctaatgcgt ggagaaacac
    16381 aaggaccgta tgattatggc gatacaattt tgacaaatgc agcaaaacaa gaacttgtct
    16441 caaaagcaat tactgttcca ctaaaatcta cagctcaagc acaaatggca aattttgtcg
    16501 tatcaaatac ttcaaaaaat aaagaaaaat cagtagaact tctagggctg cttaacagtg
    16561 atccagaatt attgaatggg cttgtttggg ggatcgaggg agaagcatgg gaaaaagtcg
    16621 atggttcaga tgataaaatc aaattgctag atggttatca gccaaataca catatgtctg
    16681 cttggaatac aggaaacaac aagattctat atacacaaga gtctattacg gatgacatga
    16741 ttgccaaacg tgatcaatcg attgctgatg cagaaacttc accgatttta ggattcagct
    16801 tcaacactga cagtgtcaaa acagaattaa gtaatatttc taatgtcatg aatcaatatt
    16861 tagatggatt gaatacaggg actgttgatc cagatgaaac attaccgaaa ttgaaagacg
    16921 ctttggacaa ggctggctat gataaggtat tgaaagaaat gcaaaaacaa tatgatgagt
    16981 tccgacaaga ataataatga ataaagacaa aggggttgtg acaaaagacg tgtcacaacc
    17041 tcttgttccg aataaacggt gttcaaaagc cagtttctcg gtattaagct aaatatatgt
    17101 aaaaatgtgg aaagccatat tcacaaaatt tttcttacta ctcgaaacta agcggctatt
    17161 tcacaaactc ttggtaaacg gtgttcaatc agctgaccct cggtattcgc tcacaaaacg
    17221 acaaaatatg aggaactatt tttccgtttg tttctctaat aatcaggtca aggtgctgat
    17281 tgcccaacct ttttttgtat aatgagaaag tataaactta atgtttggag gagaagatat
    17341 gttagggaag gttttggaag agttatttat ccggatctgg gtcattataa aactaacctt
    17401 gtatttctgg atatatacat ttgccggcgg gatcatcttt ggattaggtg cggcatggaa
    17461 aacagtcaat gaactatttt atttgtacgg attcgagtat aaagaaatca caataaaaag
    17521 aggctggaat atatataaaa gaaatttttt aagaggcaat ctgctattta gtttattttt
    17581 atctggtact gctttattga gttacaattt atatttatct gttcaaatca aagggctcat
    17641 ttttttagct attgatttta ttttactttt tgccttgctc tgcctatttg ctacttatca
    17701 atacagtatg attttagata gtgaatatac gatctctgtt cctaatctgc taaagctaag
    17761 ttttatttcg gttttttcca gcttttcgtc ttttctaaaa ataattattg gtagcggtat
    17821 aattttaggc gtgacttggc aattcaaagg attgatcctg tttggtgtca ttggtctttt
    17881 gacggtttgg aatggtacga tgacaacaca ttggcgtgaa gaattagata aacagttgga
    17941 aagttatgaa taagtttcgg attctatttt caaaaggaac cttactaaat cgtctgttgc
    18001 ggaaatacgc ggttatcatg atcggtgtaa cgatgactgc taccgttatt tttagtatcc
    18061 atacttggga acaaaatcaa aaacaggcag aaaacatgac aagtgatgcc gttcaaagca
    18121 caagcagaat gctgaatgat aaaacaacct tgagtaggat catcaaaaac cagcttgtag
    18181 ggaattccga aaagatcgaa aatgtgacga cctacttaac aaaacccata gatcagtatc
    18241 tgatgtatgt atacgaacag caaaacagta ccgatgaatt agtttctttc ccaaatcaaa
    18301 tcaaagatct ctacgcaaat tatgaagaac taagtgcgat atatatcgtg ttgaatcaac
    18361 taccggagta ttatgaatct tctagagaaa acaaaggtgg ggaaataaaa aaggggacac
    18421 caaaattact agacgccttt tatatcaagt tgcctatcac acaaggagga gctgagtcag
    18481 gaagtatttt tattggtttt caaaagaaag aactagatat gattttagaa aatctaacgt
    18541 cattcaatgg actctcttta tacatgattt ctggaacgac aaatcgacta tacacattcc
    18601 atgataataa aatagctaaa gaaacgtttg aaagacaaga aatgatcatc acagagagtc
    18661 tgaagaaaaa ttcacaattg ccgattgacg atctggaaaa aaacaatttt gttcaacacc
    18721 aagaactgtc tgatgattat cgtatattag ctgtactaga taaaaaaagt gtaaaaatcg
    18781 aaacgggaaa aaatcttgcc ccgctgatca ttggtatcat tattttagac aatatactgc
    18841 ttatctttct ttataaaaca ttcaaacgat attcacagca agtatctatc gtcatgcagg
    18901 ccatggatca aacagcagca gggaatttag agacgcggat cgacataaca aacacggaat
    18961 atgaactgaa ggaactttca atcggtatca acgaaatgtt ggatagcatc aatcagtttg
    19021 tagaagacat ctacaaatta gaaatcaaac agcaagacgc acatatgcgg gcgcttcaag
    19081 cacagatcaa tccacacttt ttatataata cattagaata tatccgaatg tatgcaatca
    19141 gcgaaggaag tgaagaatta gcagatgttg tgtatgcgtt ttccgctttg cttcgaaaca
    19201 atacgaatca agagaaaacg atcactttaa aagaagaact ggacttttgc gaaaaatatg
    19261 tctatttgta tcaaatgcgt tatcctaatc gagtagccta tcattttatg atcgatcctg
    19321 atttggaaaa gatcgaagta cctaaatttg tgatccagcc attagttgaa aattatttta
    19381 aacacggtat tgattttact cgattcgata atgcgctaag tgtcaaagtc ttgcaggaag
    19441 gcaaacgggt aaggatcatc atcaaagata atggaaaagg gatgactgaa aaacggctaa
    19501 aacagattga agaaaaactg tctcatccta aagtggaact tcacggttct atcggtctgc
    19561 aaaacgtgaa tgaacgttta cgtgccagct tcggcagcag ttattatatg tcgcttgaga
    19621 ataatgagac aggtggactg accgtttcta ttacattcaa ggagggatga gcgtgtatca
    19681 agtgttattg gtagatgatg aatacatgat tttgaatggg ttaaaaaaga taattgattg
    19741 gcaaagttta ggctttcaaa tagtagcaac agcagagaat gccaaagaag gactagctgt
    19801 acttgaacag cgacagattg atttagtagt aacggatgtg acaatgccag aaataaatgg
    19861 actggaattt attgaagcgg ctcaaaaaga acgtcataat tttgaattta tgattttatc
    19921 aggataccaa gaattcgatt atttgaaagg aggtatgcaa ttaggcgccg tgaattattt
    19981 gatgaaaccc gtgaataagt tcgaattggt tgaaagcctc aagaaaatca aaacacggtt
    20041 agatcagcaa aatgaacaaa aaaatcaaca agaaatctat caagaactgt tattcagtca
    20101 atggttgaat gaagaattgg atgaaataag tgaagaagaa ataataggac aaataagtga
    20161 gaagcagcat aggatagtat tgattcaact ggcaagaact catgatactc ttatcaatag
    20221 atggttgcaa gaacggcaac aaatctttta ctatcaacga aattacggag accgtgtatt
    20281 gatcacgttg ttgttggagg cagatgaagt tgatggcttc tgttgttttg ttcaagaaaa
    20341 ctttcctgat caggaatggc tgatcagtat cggggaagag acagattctt tggacaaaat
    20401 ccctgaaaca ttccaacaag cgaaagacaa tctacagttg catcaatttt atggagataa
    20461 agacgagcat gttttttacg cagtacaagc agaaacaaaa gatcaaacca tcgatttttc
    20521 aagtttcaga cgcgtgctgc aaaataaaca attggaagtc gctcaaaaaa tgatcactga
    20581 tttttttgaa cagtttcagt tagcagccat gatgccggaa gatatacgat attccagttt
    20641 tttactgttt atggagattc aacgggaatt gattgatctg gaagatgagg aatatttaca
    20701 aggaatcgaa aaaatccatc aggcaaaaac ggtgcaagaa cttcagcagc tacttctgtc
    20761 attcatcaaa aagcatcaga gacagaaaaa gtacagtgac aatgtggaaa aagtaatcgt
    20821 aatcctgcac cagcattatc aagaaccact tacactcaaa gaagtgtcag aaaacctgca
    20881 tttaaatgtc atgtatctag gacagctgtt caaaaaagaa acgaaaaaaa gtttttcagc
    20941 ttatttgaac catttacgta tggaaaaagc gaaacaactg cttttgcaca gtaatcaaaa
    21001 catcaatgag atagcaagtg agattggcta caacaacacc acgtatttct ctaaattatt
    21061 caagaaaatc gtcggcagat cccctaaaga gtaccgagaa aacagtggag aatcataaaa
    21121 aaaaaagcca atgtaatgaa ataacttata aaaaattgtc tagaaatcta attttgggct
    21181 gttcttatta cttgaggcaa ggcagctttt tcatgacctc tcgataaacg gagttcaaaa
    21241 gccagtttct cggtattaag ccaaatttat gcaaaaatgt ggaaagccat tttcacaaaa
    21301 tttttcttaa tactcgaaac taaacagctt tttcacgacc tctccactaa atggtgttca
    21361 atcagctgac cctcggtatt agctcaaaaa atggcaaaat atgaggaact attttgccat
    21421 ttgtctctct aatactcagg tcagaacgct gatttcacaa cctctcaata aacggtgttc
    21481 aaaagcttgc atctgcggta ataagaccaa ccaaacgaaa aatatgagga tctatttttg
    21541 cttggctgtt cttattactt gatgcaggac agctttttca caacctcttg ttaattatag
    21601 tttgataagg aaaaaggcaa atcttttgct tgatatttct tagggtgagg gatgatccct
    21661 aattggtaag agatcgtgcc gcctttcagc aaatcttgat gggtaaaata taatttcgta
    21721 tattctctgt ccatccgttt gattttatgg ataaattgtt gctgcggccg attaggcgtt
    21781 gcttcaatcg tcaattcctt tccatttgac aaaagcaaaa cagccttgtc aattaatggc
    21841 ataccgataa catattcacc ggttccaggc gtgacaggat aaaatcccag actattgaag
    21901 atataccaag cggccatact tccattgtcc tcatctccag ggtaacccat tggagaatcg
    21961 tcgaaggtct gagtcatcaa ctgtttaagc agtggctgtg ccatttcagg ttgtcctata
    22021 taactgaaca agtaaggata gtgaaaactt ggctggtttg aaatagctaa ttgtccaaat
    22081 tctatcgcgg ccatctcact catttcgtgg atctcaaaac catatcctcc tgggtcaaac
    22141 gttgggggct gattgcacag ctcaatgagt ttttctttat atctctcact gccaccatat
    22201 tttccgatca gtcctgaaaa atcgtgataa acagcaaagc tgctttgcca agcacttcct
    22261 tctgcataat cttgtcccca acgattagct gaaaatggtt ctctgaactt gccatcttta
    22321 tcttttgaac gcataaatcc tgactcatag tcaaagatat tttgatagtt caatgattgc
    22381 tgctgatatt tcttcgtcat ttcctcttct tctagtacct tggcaacttg gctaatacaa
    22441 aaatcgctat aagcatagtc taatgtgtga ttgactgatt cgtggtagtg attaggaaca
    22501 tagccatatg tcaagtaatc ttctgttcct tggcgtccat aatttggatg tttgctttga
    22561 accgtagcac ctttttccat tgccgttaga aattcaggca tcaagtctcg tcggatatct
    22621 tttacagcag catctgcaat gaccgcatcg atcaatgtcc caggcataag tccacgttca
    22681 tcaggagaca gccattttgg caaatagcca ctttctctat agctgttcaa aaaaccttcc
    22741 agcatttctt cgtatttttc tacagcaatc aaagaataaa gaggataaac cgttttatac
    22801 gtatcccaaa acccattatt tgtatagaga acaccaggtt ttatagatcg actagtcgta
    22861 tcatagtgga ttttttgccc actaggatca atttcataaa atgtttgtgg aaataaaaac
    22921 acccgatata aattatgata aaacgtccgc aattgttgtt gatcatggtg tgtgagctgt
    22981 atacgatcaa aataggactg ccattgttct tgactgtgag caaggtaagt ctctttgctt
    23041 tggttttgtt ctagttccag gttataagct gcttgttccg agctgataaa agatgtccca
    23101 aatcggatag tttgtttttt tgtctgttca aaatacaacg ggatcgagtc gctatttttg
    23161 ttggaaacag ctaactcatc aattgttaaa ggatattcaa atctcaatat aaaataaaaa
    23221 gaaaaatcag gatcttctga accagcaaaa tgtgtgattt ttccttccac tgtgtaagga
    23281 tctataacaa agagctgatg gcgtcccgga aaggataaaa gtaaaccgct gtcatttttg
    23341 ctgtaatcaa tagataagat tccgccatac atgctaggta tcaatgtaga acagatgcca
    23401 taacgtaatt gacagatcga cagatgagtc gggcaaaata tactttcttc tgggcggtaa
    23461 gaactttgag catggaaaag ggtgttctcc tgtagttttc cattgatcgg cgtaaacagc
    23521 atatgactga aatcacccat ccaaggactt ggttgatggg taagacggta gccttgaaaa
    23581 acgcggtcat caggatgaaa ccaccagctg ccgttttgat ccgtagtttg cggtgcaaaa
    23641 taattcatcc caaaaggaac gccagtataa ggctggcagt tcccattaga gaaatttggc
    23701 tgattcgctg ttgcatgtct agtatctatt tgaccgatat tcattttatt tctcctttgt
    23761 tgattgtctt ttgatgaatg aaactggaaa tttactatcg gatggtcgat cttttgtctc
    23821 taaccaagtg accaaagcat ctcccgcaag cttacctaac tgttcaaaat cttgtgcgat
    23881 ggttgtcagt ggcgggtcaa caagagctgc tgcttggata tcatcaaatc cgataattga
    23941 aaaatcttca gggatatgat aaccatgctg tctcaagaga ttcatggtct ggatagcgac
    24001 aacatcgttt tcacaaacaa aagcagttac ttcatactta gtgatataag aaagcaattc
    24061 atctaatgtc gcgcttttgt catccagtga agtgtggaaa gtcaaaccag ctttgtccaa
    24121 tgcttcaagg taaccaaggt aacgctgtcg aacggattgt ggatgagtct gcgtaccaaa
    24181 caaataagcg atttttgaat gtccctgttc gatcaaataa gaggcagcaa gcgcaccgcc
    24241 ttggaaatta tcggaaagaa cggtaggaaa aggtaactca tagatttttt tatctaatat
    24301 gacgacaggg aattctttca atgaaagctc aaaaagtaag tcaagatgtt gttctgtatc
    24361 aagagcataa taaatcaatc cgtcaaattc attgattagc tcttttgctg ttttattttg
    24421 tagaaagtca agcgtcgtca tcatgacatc aatctgttta tcttgcatca cagggttcaa
    24481 tcccttgcta aaatcaccaa cagacaaatc agcgacatat ggaagaagaa acagaatccg
    24541 tcgtgttttt gtaggagaag caagaatctg ttccggagaa gcggatttaa cgaaactgcc
    24601 tttcccgcga acgcgataaa taagtcctaa ttgctctaat tcagtcaatg cacgtttgga
    24661 agtgattctg cttactttat aggtacgtga aagttctttt tcagttggta gttggctgtc
    24721 tacaggtaat tcaccagtta aaatagccgt ttgcaaatca ttaaatattg tctggtacaa
    24781 tggttgagtc atataaacac ctcttaatga tatatcatat tcaaataata ccataatgga
    24841 tgaaaaagta aataaaaaga tattttttga aagcgtagac ataattggct gtatgaagta
    24901 taatctttaa agatatatca aatagaaaga aggttttatt agtggtttat aaagatatac
    24961 caaaatcggt gcagaaattt atggaagata tcacacaaaa atgtggggat atccatgcgg
    25021 actgggcaaa gaattttaca gcagcatttg ccaatactct gttgacaaca gtcaaaaagc
    25081 aaaatgacgg aaccaccttt ttattgacgg gagacattcc agcgatgtgg ttaagagact
    25141 ctactgcaca agttcgtcct tatttagtga ttgcaaaaga agatgaggaa ttagctgaca
    25201 tgatcagcgg gttagtcaaa aagcaatttt tttatatcaa tatcgatcca tatgcgaatg
    25261 ccttcaacga agaagctaac ggtgctggcc accaaacaga tcatacaaaa atgaacgatt
    25321 ggatctggga aagaaaatat gaaattgatt ctttatgcta cccaatacag ttggcctatc
    25381 ttctttacaa aaatacagga aaaactgatc aattcaatca atcttttatt gaaggtatca
    25441 aaaaaatctt ggacgtgttc aaaacagagc aagatcatga acactctcct tatacatttg
    25501 tacgagacac gacaagaaaa gaagatacgc tgatcaatga cgggcgaggt gcaaaaacag
    25561 cttttacagg aatgacatgg tctggtttcc gtcctagcga tgatgcttgc cgttatggat
    25621 atctggtacc atccaatatg tttgcggtgg tcgtgttagg ttatgtggaa gaaatttttc
    25681 aaacgatact cgatgataaa gaaattgtac agcaaacaca gaaattgaag aaagagatcc
    25741 aagaggggat tcagaatcac ggacgaacgg ttaatcaaaa agggcaaacg atttatgcat
    25801 atgaagtaga tggaatggga aacgccacag tcatggatga cagtaatgtg cccaatctga
    25861 tcgccgcacc ttacttggga tattgttctg aacaagagga agattatctg caaacaagaa
    25921 gaacattgtt gagtaaagaa aatccatatt tctatgaagg aaagtacgca aaaggaattg
    25981 gatcctccca tacgccagaa aaatacgttt ggccgattgc attagctatg gaaggaatga
    26041 caacgtcaga caaatctgaa aaagagcgga tattgaattt acttgtagca actgacgcag
    26101 gaacacacct tatgcacgaa ggattcgatg tgaacaatcc tgaaaattat acgagagaat
    26161 ggttttcttg ggcaaatatg atgttttgcg aattagtcat ggattacttt gatattagag
    26221 tagaaaagta ggaggtatcg taaatgaaaa agaaagtata tatcatttct catagccact
    26281 gggatcgtga atggtacatg gcttacgaac agcatcacat gcgactgatt gaattgatag
    26341 acgatctact agagctattt gaagttgatc cgtccttcaa cagttttcat ttggatgggc
    26401 aaacgattat tttagatgac tatcttcaag taaggccaga aaaaagacag gcaatccaac
    26461 aagcaatcaa tgaaggaaaa ttgagaattg gaccatttta tatcttgcaa gatgattttc
    26521 ttatcagctc ggaatcgaac gtgagaaata tgctgattgg catggaagaa agccgtaaat
    26581 ggggaacccc tgtcatgtta ggctattttc ccgatacatt tggaaatatg ggacagacgc
    26641 ctcaattaat gaaacaagct ggtatttcag cagcagcgtt tggccgtggt gtaaaaccaa
    26701 ttggctttga taatcaagtt ttggaagcag aaaactattc ttcccaatac tcagagatgt
    26761 ggtggaaagg ccctgatcaa acagcaatct ttggtctgct atttgccaat tggtatagca
    26821 acgggaatga gattccagta gaaaaagaag cagctcttgc cttttggaag caaaaattag
    26881 cggatgcaga acaatatgcc tctacgaacc acttattgat gatgaatggt gttgatcatc
    26941 aaccggtaca aaaagatata tcaaaagcaa tccatctcgc aaatgaactg tttccagatt
    27001 acgagtttat tcattctaat tttactgact atctggaagc agttcaaaaa gatgtgccag
    27061 aagacttagg ctcagtagaa ggagaattga caagtcaaga aacggatggc tggtatactt
    27121 tagccaatac agcatctgct cgggtttact taaaacaatg gaataccaag gtccagcgac
    27181 agctagaaaa tattacagaa ccacttgcga cgatggctta tgaagttagt ggaaactatc
    27241 cccatgatca attagattat gcttggaaga cattaatgca aaatcatcct cacgacagta
    27301 tttgcggttg ttcagtcgat tctgtccatc gggaaatgat acctcgtttt gaaaaagcag
    27361 atgaagttgg aaagtatctt gcacaagatt ccttagaaca gctgaccgca gcaatcgata
    27421 cgaccggatt cccaaaagac agctttccat ttgtcattgt aaatactgca ggaatggata
    27481 aaactggtga agcagaaata accatcgaat tagaaagaaa aagattcgct gaaggaatac
    27541 ctgaacaact atatcaagag ttagaaaatt tgcctaaacg taagtatcat gtagaaacaa
    27601 aaagtggggc cactatacca gctattttat ctgaagaaac tgtccaattt ggttatgatt
    27661 tgccgaaaga ccgtttccgt gtgccatata tggcaagaat gatcaaagtg actttaccat
    27721 tagaaaacat gccagcattt tcttgggaaa cattcgcgct tgtagaaggg gaagcgaaag
    27781 cagaagaaaa ggaaacaatg attcatcaga gtggacgaat catcgaaaac ggccctctac
    27841 atttgacgat tgaaaaaaat ggtaccatta caatggaaga tcgcaaaaac aaacgaaagt
    27901 tgaataatct gcatattttt gaagatatcg gcgatatagg aaatgagtat atctttaaac
    27961 aacctttctg tgatcagcca atcctatcca gtaacaaaga aaactctgaa gtaaaagtat
    28021 tagtagatac accggaaata gcaaaaataa gtattctaca ggaaatggaa atccctgttt
    28081 ctgcagacga gcgtttagaa aaagaacagc agatggttgt ggaatttcgt tatcgaaaag
    28141 cagaacgatc caaagaaaaa cgaatccttc aaataaaaac aatcatgaca atcagaaaag
    28201 atagtaaaaa aatcgacttt gaaacgactc tcgacaatca gatgaaagat catcgcttac
    28261 gtgtcttgtt tcctacaaag ttacatgtgg aacatcacga agcagatagt atttttgaag
    28321 tggtgaagcg cccaaaccat gtgtctaaaa gttgggaaaa ccccacgaat ccgcaacatc
    28381 agcaagcatt tgtcaatatt catgatgaag agtacggtgt aacagtcgga aactttggtt
    28441 tgaatgaata tgaagtaaca gaagacggac aaatcgcagt gacgctactt cgcagtgtgg
    28501 gagaactagg cgattgggga tattttccaa caccagaagc acagtgtcta ggtgagcatc
    28561 ggttcaatta cagcattgaa ctacatggac cagaagaaaa attctctact tatttgcatg
    28621 catacgcagc acagattcct ttttccactc aacaaatcaa acatcatgaa ggaacattga
    28681 tttcaaaaca acaatattta acgataaaaa gtgaaacgtt tgcaattaca gctttgaaac
    28741 gcagcaagtt tagtgataaa gtagtagtaa gaggtttcaa tatgtctagt catttagaaa
    28801 aattggaaat aactaaagac aatggaaaaa ctgtcatatt gaatctgctt gaagaaccaa
    28861 cgaagcaagc ggttgtccca ataatccaac cttatgagat tcggacaatc ggattcgagg
    28921 aggaaaacga atgtatggcg gaatagaagc aggcggaaca aaatttgtgt gtgcggtttc
    28981 agatggtgga gaaattttag aaaaattaag tatccctacc acaacaccag aagaaacatt
    29041 ggatcaggta tttgaatttt ttgatcgtta tgaattgaag ggaatcggga ttggctcatt
    29101 cggcccgatt ggtatcgaca aaacaaaaga taattacgga tacgttttgg caactcccaa
    29161 aaaagggtgg gcacaattcg attttcttgg cacaatcaag gaacgctaca atattcctgc
    29221 tgcttggaca acggatgtca atgctgctgc atatggggaa ttgaagcaag gagcagcaca
    29281 aggaaaaaat agttgtattt accttaccgt gggaacagga atcggtgcag gtgtcgtgat
    29341 caatgaagaa attttttcag ggatcgcaca tcctgaaatg ggacatattt gggtgaaacg
    29401 ccatccagat gaccattatg aaggtacttg tccttatcat aaagattgtt tagaaggatt
    29461 agcagcagga ccgtctattg aggcacgcac agggatcaaa gggcaagatc tgccgcaaga
    29521 tcatcctgtt tgggctattc aggcttatta tattgctcaa gcactgatca actatacgtt
    29581 gacgttagca cctgaaaaga ttattttagg cggtggggta atgaatcagg atcatctcct
    29641 tcaaaaaatc cgtcagcaat ttgttgaatt gatgggtggt tatatggaaa cacctcaagt
    29701 aagtgaatat atcgttcgtt ggggactgcc gaatgaaagt gggattatcg gtagtttgct
    29761 gttagcagaa cacgaacatc aaaagtaagc agacaaatta cacaaaaaga acagagtctt
    29821 atcattatct gctgataaga ctctgttctt ttttatttct attcccataa tccaggtaaa
    29881 gctttaccga ctattttttc ttgagtaaat ggatggatca tgtgcagttc taatgcatgg
    29941 agcatcagtc gttcagctgt tctattttgg tagagagggt ctccaacgat cggatgtccc
    30001 ttatgagcta aatgaactct gatctggtgt gtacgtccgg tttccaaaac acaatagact
    30061 tgtgtttgtt cagaaagtac tttgttgaca gtgacatgtg tcaaggcgct ctgaccattt
    30121 ttatcatcta cgaccctttt tctccgatca tggcgatctc gtccaatttt attggtgatg
    30181 gtcatatctt tggcaatttc tccccatacg atggcttgat atctccgata gatcattttt
    30241 tgttccaaca ttcttccaag tatcggcaag acaaatggat tttttgcaaa taaaacggca
    30301 ccgcttgttt ctttgtccaa gcggtggaca acgtaaggtc gttgctgttt agtgtcgaga
    30361 taagcagcta aatgattgag taaggtactg ttttctgtcg gttcatttgg atgagtcttc
    30421 attcctgcag gcttatccac tataatcaaa tgctcatctt catataaaac acggatgtgc
    30481 ttcgcatctc ctaattgaac ttcttgataa ttataatctg tttcttcgaa taacaatgtg
    30541 atctggtcat tgccctttac ttcatgatgg aacaaagcag gttgttgatt gatccaaacg
    30601 tttttacgta tacgcaaaaa gtgtcgaacc tttctaggaa ctaaccattc cttttcaagc
    30661 aagtcgcgaa ttgttgtttc aggatggttc ataggtaaag tgatcgtgat tttcacaagt
    30721 gtactccttt cagtgcaatt gcagactaat tgtaccattt ttaaaacata tttaagaaaa
    30781 aacttacatt tttctgttca ttcttatgtt actctacttg cactaacgta aaaaaacata
    30841 ttgaactaca acttaagcag gaagaaaaca ctctttcact atggtaaaat aagacgattg
    30901 aatcaaatag acaggagaag aagcaaatgg attttcaaag cattttagaa aagataaaag
    30961 ctgctttgat cagtttttgg cgttggatca gaccatatct cggacaattc catcgatggc
    31021 gaaagcgcat ctggaaaaaa tatcatgtga acaaattgat tttgctgatt ggtttgatct
    31081 gtgtcttagt gacaagtatc tacctcttta ttttagcaaa acaagcaaat gtcgaaacgt
    31141 taaaatcagg attaagccaa tcgacagtca tttatgataa gaaaaacgaa gaagctggca
    31201 cactgtacgc ccaaaaagga acatatgtag aattaaacgc gatttctccc tatatccaag
    31261 atgcagtaat ctcgacagaa gataggaatt tttacgagca tcacgggttt gatatcaaag
    31321 ggattgcccg tgcagcagtc cgaatggtct tgtctggcgg aacatcaggg ggcggaggaa
    31381 gtacgatcac tcagcagctt gccaaaaatg cgtatctgac attagaccaa acgtttgatc
    31441 gaaaagcgaa ggaattattt ttggcaatcg agatcgaaaa gaagtacagc aaagaagaaa
    31501 tcttgaccat gtatcttaac aatgcctatt ttggcaacgg ggtatggggt gtccaagacg
    31561 cttccagaaa gtattttgga gtagatgcaa cgaatgttac gctgtctgag gctgctactt
    31621 tggcaggaat gctgaaaggt cctggtattt ataatccgat cgatcaccca aaaaatgcga
    31681 atgatcggaa aaacacagta ctaagtgtaa tggaagaaaa cggaaaaatc acaaaagaac
    31741 aagaacaagc agaaagccag acagatatca gcgcgtatct taatgacaca tacgataatt
    31801 cagattctgg ttatcgttat ccttattatt ttgatgcagt gatcgatgaa gcagttaacg
    31861 agtatggtct tgatgaagaa gatgtcatga ataaaggcta taaaatctat acagctttag
    31921 atcaggatta tcaaaagcaa ttagaagcta cttatcaaaa cagtgcatta ttcccagcaa
    31981 atgcttcaga tggtgccatg gtccaatctg cttcagtagc tttagatccg aatacaggtg
    32041 gtgtacaagc actagtagga cgaagaggag atcatgtctt tagaggattc agctttgcta
    32101 cacagatgcg tcgttcacca ggatcaacga tcaaaccatt aagcgtatat acaccagcac
    32161 tggaagctgg atacaagcct tccagtatct tgaaagacga accgcaaagt tattacgatg
    32221 cgcataattt tgacgggaca taccaaggag aagtaccgat gtatcaagct gttgcacaaa
    32281 gtttgaattt gcctgctgta tggcttttgc atgagatcgg tttacaaaaa ggatatgata
    32341 aagcagaaga attcggcctg cctttagcaa aatctgataa gtattatggc ttagcccttg
    32401 gtggactgga aaaaggagta tctccattga tcatggcggg tgcttacagt gcatttgcca
    32461 atgatggtca gatgtatacg ccgcatctta tcacgaaaat cgttgattcg actggagcgg
    32521 tgatcgtcga taacacaaac aaaaaaccaa aacaggtcat atcaaaggaa acagccgatg
    32581 aaatgaccag catgcttctt ggtacatttt caaatggaac agcggctgct gcgaatcctg
    32641 caggttatac gatagcaggg aaaacaggaa ccacagaaac taatttcgat gccacaaaag
    32701 caaatgacca atggatgatc ggttacacgc cagacgtagt gatttcgaca tggatgggtt
    32761 acgaagaatc cagcaagctg cactatttgg aagggacaag tggaaatgtt gtcgggaaag
    32821 tcttcaaatc agcggcagaa ggcatccttc cgtatacttc aaaaacagga tttagtgtag
    32881 cagatgccta tgccacagga ggacaagtgg tagctgcaga tcaagttgga aacacaggaa
    32941 attctaatgg agagtctgga aattggcaag ataacttgaa tcaatatggt gaacaagcaa
    33001 aagaagggct gaaaaacttc ggcgatatgg tgaaagaagg cgttcaggga attggtgaag
    33061 cggctaaaga cctctggcgg aaatatcaag gagagtagcc cctttgaaaa cgaataaccc
    33121 catgttacaa tagagagtaa ctactaaaag aaaagagggc ataacatgtc aaacatctac
    33181 gatagcgcga atcaaatcga acgtgagatc cgtgaattac cagaattcaa agcgttgaaa
    33241 gaagcgtacg agaaagtaca agcaaacgaa gaagcacaca aactgttcaa agacttccaa
    33301 gcgatgcaaa tcgaattaca agaaaaacaa atgagtggac aagagttcag cgacgaagat
    33361 gcaatgaaag cacaagaaat ggctgtgaaa atccaatcag aagaagtaat caatgacttg
    33421 atgcaaaaag agcaaggctt cagtacaatc atcaatgact tgaaccgtat catcatgaca
    33481 ccagttcgcg acctttacag cgaataaaac tattttatga aacaacagag ggtgtgaaag
    33541 agacgttcgg ccttgagcga tgacaaaatt gcttcttatt gccgataggc tgtctcttga
    33601 acaccattta ccaagaggtc gtgagcctac cgtttaactc tgagttacaa ggaacaattt
    33661 caaaaaacag cttctcatgt ttgatgacta ttgtgacttg tgaccgagga gttggcagga
    33721 gaacaccgtt tattcagaaa taggagctac gacaaaagtc ttgtcatagc tcctattttt
    33781 tgtcattcat ttttcaagcg gtagaaatag cctttttgag ctaacagttt ttcgtaagta
    33841 cctatttcaa cgatttttcc ttcatcgatc acaacgattt tatctgcctc tttgatcgtt
    33901 gaaagccgat gagccacaat aaaagtagtg ggtgtttctg tcaggtaatt cagggcttgc
    33961 tggatttttt tctctgactg gttatctaaa gctgaggttg cttcatctag caaaatgatt
    34021 tttggctgac gtatcaacgc tcgtgcaatg gagatacatt gcttttggcc accagacagc
    34081 ttgttgccat gttcgcctac taaggtatcc agaccatcag gaagctggtc aatcagtgaa
    34141 gaaagttgcg cagcttcgat gacttcatct aaacgttctt ttgatacgtt tttcaagcca
    34201 taagtgatgt tctctttgat cgaagcggag aacaacaaag tggtttgagg aacaacggct
    34261 aaataatttc gcacacttcg catatccagt tcatccaaag gctgatcatc tagaaaaatt
    34321 tttcctgaag tcggctggat aaatccaatc aataagttaa ggagtgtaga ttttccagag
    34381 ccagatggcc caacaaaagc aattgtttct ccagctttca cctctagaga aaaatgatcg
    34441 ataatcggtt tgagtgagtc cggataaaga aaagaaacat cctcaaaacg aaaatttcca
    34501 tccaaatgtt ggattttttt cttaccgtga taagtttcta catcgccagc aatcaacagt
    34561 tcgccaatag aagtgataga ttccatgcct tttgaaatcg taggaatcag cgtgatcatt
    34621 ccagaaacgg aattgacgat cgtcgtgaaa tacgtctgat acatcacgac atcgccgggt
    34681 tggatgcgcc cttgtaaagc taatatccca gtgaaactca aacaaatcag ctgaaatatc
    34741 tgaaaactag cccagctgac tgatccgaaa acagattgca ggatatctaa gtggaatcct
    34801 ttttcataga tttgagtaaa atgcttattt aagcgagttg tttcgtgttt ttctaaccca
    34861 tgagctcgag caatcggtgc taattcgatc acttcgatca cttttgcaga agtctcttcc
    34921 atttcttgcc tgaagtctga gttggactgt ctgatccttt tacggaaaaa gagagtaacg
    34981 aatgcggcga gaggaacagt caataagaaa aacatgaaaa caacaggact tttataaagc
    35041 gtgataccta aagctacgaa taaattgaca gcgatattta atccgctgac aaatacttga
    35101 gaggacaacg tttggatagc ttctacatca cggatgatct ttgactggat tcgtccagat
    35161 tgcaattctt tttgataagg aatagatagt tcttggattt tcttgataag ggtcgctctt
    35221 agtccagctt ctacttgacg gatcgaagtg ctatggtatt ttacatgaaa ataattcgtc
    35281 aatatatttt gaccaatcag acaagccatc aaaaaagcgt tgaaataaat ggcctgcaac
    35341 tgagaagaat ctttcgatga agctgcattg attacattgg caatagcgat cggcattaac
    35401 caagatggaa gatgtttgat aataaaaaag agtcctgaca tggcaaaacg ccaataattt
    35461 ccctgataaa gatgcagcaa tgtctgaaaa gcatttgcat gatatttttg ataacttttc
    35521 tgtattcgtt cctccataat cttctcctta acaatcttgg taaataaact gcaagtgttc
    35581 tattgcttca ggaacataaa tctcaggagt agcttcaaga gtggcgtaca ttagaggacg
    35641 ctcatatttg atataatgca gtaccgggcg gaaatctaaa cagcccttgc caacaggtac
    35701 catgcggatc tttccatttt ccatgatata gtctttgaga tgaagcgctg taatataacc
    35761 atgtaaattg tccaaggcac ctcggatcac tttttcctga tcagcatgat tttctttatg
    35821 catcaaattc gcacaatcta aaatgatttt taaatttggt gaagctactt catcgattaa
    35881 acgtttagct aactgatagt tatagattgg atgattgatc cctgcttcaa cagcaacagt
    35941 tacgccaaaa ttttctgcat gagcgactaa ttcaatgata gaatttctgg cgatctgata
    36001 agcttcttca gtaaaatttt cttttgtgta accgacagag acactaccgg tttccgtagc
    36061 aatcatcttg gcttgatagg cagagcacag agcaatttgc tgtttgaaag ttgccaatgc
    36121 ttgtgcacga acttcttgat ttttgctgga taggttgata tagcatccta aaatggaaag
    36181 ttcgatattg tttttttgga agtattcacc aaaataggca gcactcccaa gtgtcatgtc
    36241 agttaattta agttgttcag gaaatgcttt ttgtggtgca aattggatat gggacaagtg
    36301 aagctgtgat actttttgaa cgatttcttc acgatttcga acatctaaat cgtgggcacg
    36361 gatgcctaaa tttaatggaa acatctcaaa ctcctttttg taaataatta gcaagaggca
    36421 gacgggattc ttttatcaat tcaacaatta ttcgggcaac tttatcagcg ccttctggac
    36481 taaagtgggt attgtctttt agtccttctg ggtaattttt acaagtatca ggcataagat
    36541 gcaggtagaa tttttttgtc tcttcttttg agaaggtctg gaacaattct tgtgatcttg
    36601 agaacacatc taaaagagga atatggtgtt tctcagcaaa tgcacgcatc gcttttggat
    36661 agtctccaag tatatctgga ttcaatgttc cgttttctaa gtaatctcgt cgcgtcacag
    36721 atgtcagtaa gaccatttgg acgttcgctt tttttgcgca ttcaaaaaat atctgcagat
    36781 tttttaaata gctaccgaag ggaagcgtac ctctttcttc ttggattttc tggtcgttat
    36841 gtccaaattg tacaaataag aaatcattcg gctgaaactg tgaagctaga cgggctaacc
    36901 ttccttcctg gataaatgat ttggtgctgc gtccattctt tgcttggtta ttgatctgga
    36961 tctcgggtga aaaataagca gagatttttt ctccccaacc tgtctcggga cgcttgtttt
    37021 catctttttc tgccgcagta gaatcaccgg caatatggat agtaggcatg ttatctcttc
    37081 tttcataaag gtttataggc aatgaagcag aacagcaaga gaagaagacg gagcaa
//
LOCUS       DAZULR010000027        36951 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.027, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000027 DAZULR010000000
VERSION     DAZULR010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36951)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36951)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36951
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.027"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..1033)
                     /locus_tag="ACG8ZV_001548"
     CDS             complement(<1..1033)
                     /locus_tag="ACG8ZV_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFS4996896.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVL"
     gene            complement(1062..1379)
                     /locus_tag="ACG8ZV_001549"
     CDS             complement(1062..1379)
                     /locus_tag="ACG8ZV_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFS4996897.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(1405..1725)
                     /locus_tag="ACG8ZV_001550"
     CDS             complement(1405..1725)
                     /locus_tag="ACG8ZV_001550"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFS4996898.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(2189..3604)
                     /locus_tag="ACG8ZV_001551"
     CDS             complement(2189..3604)
                     /locus_tag="ACG8ZV_001551"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFS4996899.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(3621..4937)
                     /locus_tag="ACG8ZV_001552"
     CDS             complement(3621..4937)
                     /locus_tag="ACG8ZV_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFS4996900.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(5087..5785)
                     /locus_tag="ACG8ZV_001553"
     CDS             complement(5087..5785)
                     /locus_tag="ACG8ZV_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="HFS4996901.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            complement(6074..7063)
                     /locus_tag="ACG8ZV_001554"
     CDS             complement(6074..7063)
                     /locus_tag="ACG8ZV_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFS4996902.1"
                     /translation="MYIADSARYEKMEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQ
                     REILRGAFDMGITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMW
                     EGPYGEWGSRKSIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGK
                     ALYIGISNYNGEDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGA
                     ITFSPLAQGLLTNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQS
                     LAQMALAWNLRQKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
     gene            complement(7143..7976)
                     /gene="msrA"
                     /locus_tag="ACG8ZV_001555"
     CDS             complement(7143..7976)
                     /gene="msrA"
                     /locus_tag="ACG8ZV_001555"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFS4996903.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQVERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            complement(8151..9785)
                     /locus_tag="ACG8ZV_001556"
     CDS             complement(8151..9785)
                     /locus_tag="ACG8ZV_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-pyruvoyl-tetrahydropterin synthase-related
                     protein"
                     /protein_id="HFS4996904.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFN
                     QKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNL
                     PYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGV
                     ADIKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            complement(9772..11460)
                     /locus_tag="ACG8ZV_001557"
     CDS             complement(9772..11460)
                     /locus_tag="ACG8ZV_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996905.1"
                     /translation="MKISKKAFLLVVLILLSTLYSVNFMRNAQEIYTTGDLSFHLSRI
                     KGLSSIFEGPINYTTFNNYGDGLNYFYPFLTIIPAVVFYGISNNLILSYVLYIWLLNI
                     CTILISFYYGEKFFKKIDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVLYY
                     AYGLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIKFV
                     VVNLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNNDI
                     TTYTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPISLL
                     QFPWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAKVI
                     QSKHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKYKA
                     ADNNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENKIE
                     ITTKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
     gene            11606..13243
                     /locus_tag="ACG8ZV_001558"
     CDS             11606..13243
                     /locus_tag="ACG8ZV_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996906.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSKGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(13388..14128)
                     /gene="truA"
                     /locus_tag="ACG8ZV_001559"
     CDS             complement(13388..14128)
                     /gene="truA"
                     /locus_tag="ACG8ZV_001559"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HFS4996907.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(14319..14954)
                     /locus_tag="ACG8ZV_001560"
     CDS             complement(14319..14954)
                     /locus_tag="ACG8ZV_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HFS4996908.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(15101..16321)
                     /gene="sstT"
                     /locus_tag="ACG8ZV_001561"
     CDS             complement(15101..16321)
                     /gene="sstT"
                     /locus_tag="ACG8ZV_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HFS4996909.1"
                     /translation="MSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSCLKAIAPI
                     LVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPITLQETVSE
                     KAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSESTKELVDQI
                     SIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLFVALVVYP
                     FLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKESYSISIP
                     LGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGVAGGSLLL
                     IPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELGARKRSGE
                     KIKLKDCLDGLSER"
     gene            16540..17538
                     /locus_tag="ACG8ZV_001562"
     CDS             16540..17538
                     /locus_tag="ACG8ZV_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996910.1"
                     /translation="MFLSNFFVRCLFLKKIKKESYGFLTIFVACIMMVLQRILISAVT
                     IPTYATNPGRFYIYTFLQTSVVIGANLIPLYMGYQYQKIARLKVLHYLSRFAFIFLIA
                     TLVCNIFFYVQAGSLNIRDYWLILTPISQNYFTYAVSCTLLFCSIPYTVGFLNKLSKT
                     TIKYLLLFLTIGLVGCSTLFNKDPFALQNGQSILWIFYLFLMGYGLKEWNWKEKVRYK
                     LPQVFISLIVLFGLIILMTQISLIIRGNTDTALRFSKPYSLFAMYYTFSSFLFLEMLS
                     DKLGIKGRGNFLAVFLIVTQVICNFPLVSYRVSTFMKREFPNSGKAWLINIGQFFI"
     gene            17734..19569
                     /locus_tag="ACG8ZV_001563"
     CDS             17734..19569
                     /locus_tag="ACG8ZV_001563"
                     /inference="COORDINATES: protein motif:HMM:NF013080.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFS4996911.1"
                     /translation="MQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFFFLL
                     LLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKMLTGLSELLSMVSPVL
                     LIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHKNSP
                     SFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMKKYN
                     TKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTGGLM
                     LSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIAIHP
                     FTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQSNT
                     ETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAVKKF
                     IQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAATLNK
                     EVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVFVTE
                     DSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQKIKD"
     gene            complement(19629..20345)
                     /locus_tag="ACG8ZV_001564"
                     /pseudo
     CDS             complement(19629..20345)
                     /locus_tag="ACG8ZV_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299292.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
     gene            complement(20572..21114)
                     /locus_tag="ACG8ZV_001565"
     CDS             complement(20572..21114)
                     /locus_tag="ACG8ZV_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008199 - ferric iron binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin-like domain-containing protein"
                     /protein_id="HFS4996912.1"
                     /translation="MNIVEEKFVQETKQADIDHHKPTAGAMVGHVLANFKLEEMKLIQ
                     AQLYVLGTSSQELSTLFSEYADQEARWFNKISHELVIENEIVPSTLEEVMRYGKIYEH
                     GQNKYLPASTMLENFAKDFDFQNVFITRAIKLAEKEEKYGLQQLLVELLSFNKEIIYQ
                     VQRLQGKTVRQDLDEEDDDD"
     gene            complement(21119..21346)
                     /locus_tag="ACG8ZV_001566"
     CDS             complement(21119..21346)
                     /locus_tag="ACG8ZV_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HFS4996913.1"
                     /translation="MKKIIMQLDTLACPSCMQKIEHAVSQQPGVSNTKVLFNASKIKA
                     NFDPDEVHPEQLAAVVEKLGYEVQSAKVKEA"
     gene            complement(21425..23305)
                     /locus_tag="ACG8ZV_001567"
     CDS             complement(21425..23305)
                     /locus_tag="ACG8ZV_001567"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFS4996914.1"
                     /translation="MKLQKWIQEHRNHITALSAVLIIFGFIGKFTGFVLFYNIALAIA
                     SIIAVIPIMIHAYQAVKVKVISIDLLVTIAVLGAFMIGEYKESAIVTFLFLFGSYLEQ
                     KTLTKTRESIKALTEMAPSTASVVQEDGTTEEVEIDDVEEGDIVLVKTGGAIPVDGRV
                     IDGKGYADEAAVTGESRQVVKISGDEVFSGTILADGYVTIEATKVGDDTTFAKIIELV
                     EEAQDTKSHAEKFIDRFSQYYTPTVLLIALVVGLISRDFRLAITVLVLGCPGALVIGA
                     PVSNVAGIGNGAKRGILVKGGEAMDTFSKIDTFVFDKTGTLTKGTTAVSTIKNYTEDE
                     GDSLALVARLETLSDHPLGRAVIHYAQEKDIDFQQLAVKDNQTIKGQGITAEIDGHTV
                     CAGNTKLIAAHKLSLTPKQVQDLHQLQQTGSSVIIVAIDKKITQIIGVSDVIRPEVAE
                     QLAKLKQAGAKQLVMLTGDNQMTADYVADMLGIDEVHAELLPDEKVQFVKKYQEQGLR
                     VAFIGDGINDSPSLAAADIGIAMGSGTDVAIETSDVVLMQSNFESLVHAYRLAKKTVL
                     NTRENVVIAIGVVLFLLNGLFAGFIYMASGMFVHEASILIVIFNAMRLLYFGHESKEE
                     KS"
     gene            complement(23494..24108)
                     /locus_tag="ACG8ZV_001568"
     CDS             complement(23494..24108)
                     /locus_tag="ACG8ZV_001568"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4996915.1"
                     /translation="MKLTFKPLEKKDYKKAIYFAVEGMNFERYMENELLLNLYGRYFL
                     YMELNRATQILALYAEDELAGVLLAEIKGEKKKHRSFGQQIYVKIFDFLQNIFAKESK
                     GAYETANEQMLAAYLKKHSPDGEIIFLAANPDLKTKGIGTKLLTEFEKREKGKEIFLF
                     TDSGCTYQFYERRGFERLKEKISKIKILDKEIDLRCMLYRKIIQ"
     gene            24250..24810
                     /locus_tag="ACG8ZV_001569"
     CDS             24250..24810
                     /locus_tag="ACG8ZV_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFS4996916.1"
                     /translation="MKKTDRRVKKTEKALAETLSTLLVNKKIQAITIRELTETADVHR
                     STFYTHYKDIYDLYDQLESNFFRDLNEILSYDPAHSYEELYTRLIDYVYANTFLYRLF
                     ILNHGDISFQKKVKQVIEENYLNIWLYEDKKTIITEEMRFFTTYHVQGCLSVLNRWVE
                     SNYKYSKKELLELLQKLNDHIEKIMP"
     gene            complement(25130..25429)
                     /locus_tag="ACG8ZV_001570"
                     /pseudo
     CDS             complement(25130..25429)
                     /locus_tag="ACG8ZV_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
     gene            complement(25683..27318)
                     /locus_tag="ACG8ZV_001571"
                     /pseudo
     CDS             complement(25683..27318)
                     /locus_tag="ACG8ZV_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294751.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(27757..28626)
                     /gene="scrK"
                     /locus_tag="ACG8ZV_001572"
     CDS             complement(27757..28626)
                     /gene="scrK"
                     /locus_tag="ACG8ZV_001572"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HFS4996917.1"
                     /translation="MYGSIEAGGTKFVCAIGNDDLKVLERVSFPTTTPNETMSLVIDF
                     FNHYKEQLESIGVGSFGPIDIHRESKTYGHITSTPKTAWKNFDFVGTLNKHFEIPIAW
                     TTDVNAACYGEYVSGHGKGLSSVVYYTVGTGIGGGAIQDGIFVEGFSHPEMGHTLVKR
                     HSGDTFSGTCPFHHDCLEGLASGPAIEMRTGTKGQDLSIEDPFWEIEADYIAQCACNT
                     TLMLSPDIIIFGGGVMQQEHLKKKVQRRFLELINGYVDTPNIEEYIVTPKLADNAGTI
                     GCLTLAKDVRINS"
     gene            complement(28646..29767)
                     /locus_tag="ACG8ZV_001573"
     CDS             complement(28646..29767)
                     /locus_tag="ACG8ZV_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 172 protein"
                     /protein_id="HFS4996918.1"
                     /translation="MNCLNNIWLHKGEESRTISPENKNGEKGKAAMTASHLGIGRKGS
                     PSVPINAGETITLAEMEGPGILRHFWMTVTDKTIAGSFVLRDLILRIYWDDESTPSVE
                     SPLGDFFCNGFGTRCEVNSLPIVVNPTSGMNCYFEMPFRKKAKITLTNEHPEFIKHIF
                     YTFNYALTEVPDDAMYFHAKWNREPITTKGKDYTLIDGIKGTGYYVGTYFALCALERY
                     WWGEGEFKFYIDGDEDFPTITSTGAEDYFGGAWAFHKKNFGERAYAQNFNTLFMGYPF
                     QSKRDHTRDYFSAGKPNPNPVHGFGDDALPMHGLYRWHLPDPISFKENLRVTFQTLGN
                     DDIKLYERQDDISSVAYWYQKEPHEFFEKLLDREERIPR"
     gene            complement(29769..30164)
                     /locus_tag="ACG8ZV_001574"
     CDS             complement(29769..30164)
                     /locus_tag="ACG8ZV_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFS4996919.1"
                     /translation="MRRLIIASHSILAEGFKETLEFLTGMHNQISSLCAYVEEIDDID
                     EQIKELVDTTDEIIVLTDMAGGSVNQKFFTYISDRVHVIAGMNLPLAMSIALQLGNDN
                     LDIGAIIAEAQQQIIYMNNQKSEERIEDE"
     gene            complement(30183..30980)
                     /locus_tag="ACG8ZV_001575"
     CDS             complement(30183..30980)
                     /locus_tag="ACG8ZV_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFS4996920.1"
                     /translation="MSEKYQVTKKDLRKANYRWLMSVCTFNYQTQQGASVTYALSPIL
                     RKLYKDDDEYIEALNNHFQYYNTQPWLAAIILGACVAMEEKQGLEAKDAINDFKVGTM
                     GPIAGIGDSLLMTMIPTIMGSIAAYMALENNPVGIFLWFILIMVIFFFRMRGFEFGYK
                     QGMKIVTEYGEKINYLTEAASVLGLTVVGSLIASVISVSTPLKFTFGEVSMKIQPMLD
                     KILPTLIPVIITAAAYYLLSKKKISMTILILLVIVFAMVMAAFGILA"
     gene            complement(30982..31770)
                     /locus_tag="ACG8ZV_001576"
     CDS             complement(30982..31770)
                     /locus_tag="ACG8ZV_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFS4996921.1"
                     /translation="MHFTIFQIIMLTILAFIKHVDYYGIPMIFVNYAVFWGLFTGILM
                     GDIKTGLIVGGTVQLMSLGVAGFGGSSVPDYGTCAIIATAFGSQLGVEAGLAIGLPVG
                     MLGVQLDVIVKILNGFVVRKSQEYANKREFKKMNSVLWLGPIFFGLSAAIPVFIAVTL
                     GQSAVNYVLDVLPNWFMDGLTLAGKMLPAVGIAMLLRFMPTGRYISYLLVGFFLAAFL
                     KVPIIGAAIIGFALAFNVYHRAEKDAQITASAGASDVGFIGEDE"
     gene            complement(31784..32260)
                     /locus_tag="ACG8ZV_001577"
     CDS             complement(31784..32260)
                     /locus_tag="ACG8ZV_001577"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFS4996922.1"
                     /translation="MSIVMSRVDNRLLHGIIVTQWAPMSKANRVMVIDDSVANNDIQK
                     SSMRLARPAGMAVSIITEETAIANFKKGKYDQEKVFVIVKEPETILHLVDNGIRIDRL
                     IVGGTVVKDNALQLSSRAYASDENISTYKKLLDSGVEIVTQFVPADKAQEIQSKLG"
     gene            complement(32332..34989)
                     /locus_tag="ACG8ZV_001578"
     CDS             complement(32332..34989)
                     /locus_tag="ACG8ZV_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFS4996923.1"
                     /translation="MEELKERIVNYVIENSEIKNKWGNNTAQKISEKLNVSRNIVSQY
                     LNEFVKDGEFGKINTRPVIFFSLPEKVPNQQIFSSSEEAEKWYDSSFRVGIERVIGSQ
                     GSLRNVIAQIKAAIYYPPNGLPILLHGETGTGKSYLANYVYKDLLANNYIEEKASFIS
                     VNCSEYANNPELFLSNFFGHVKGAYTGAEDGRKGLAELANNGVLFLDEIHALSNECQE
                     KLFQFMDTRKFHRMGDNENWYTSSCWIIFATSEPPEDKLLSTLLRRIPVKLTLPTLDS
                     RSLYERKQLIKIFFKSEEERLAKKILISQQLLDFLLNYRFSENVGNLKNIIQLTCANA
                     FYFLDDLEELYIQMYHLPQWVNFNGMKVMKRQNELKYIQMDDLEKVDEVFNINELIEY
                     LYQTWKKDTDKQQLFEKYDRYFRQKNVDIQNNSALTYPTYQEIRFRQYVKEIERDFQI
                     EFDYYYLQITSIFLNSWIYQIQLTSDDKLYSFINDINSWCSREVQLVNRFIQIGDIYL
                     TKIQKNVLVILFKLMCSKEFQQKRLALILAHGDLTATCIASTANRIVERYIYDAIDMP
                     LMTSSSEIADKINRYLQECTGYEEIILLVDMGSLEKIYLNLELDAQKKFGLLNNVSTR
                     MAIDVANQILLDLPLKQILEQVKENQNVDYIYESSNIKKDMIVCSCASGLGTSFKLKK
                     ILEDSFPRDTDLVIETCDYYSLVNENYLSELRKENNILFIVGTLNPHLEDVEFFSIED
                     MILGMNISKFSNQLNRHFNDNELKVLNNNILKNFSLTNLMEQLTILNPTKLLERVSDA
                     IYILQNDLGISFDNNTCFGLYVHISCLIERLVKQNTLEDEIYFNETSEEFQKFQTHFK
                     QSFSVVEHYYSVDIPIHEVKYVYDYVKRA"
     gene            complement(35053..35412)
                     /locus_tag="ACG8ZV_001579"
                     /pseudo
     CDS             complement(35053..35412)
                     /locus_tag="ACG8ZV_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit M
                     N-terminal domain-containing protein"
     gene            complement(35590..35910)
                     /locus_tag="ACG8ZV_001580"
                     /pseudo
     CDS             complement(35590..35910)
                     /locus_tag="ACG8ZV_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328113.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(36026..36547)
                     /locus_tag="ACG8ZV_001581"
     CDS             complement(36026..36547)
                     /locus_tag="ACG8ZV_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996924.1"
                     /translation="MDKPFLDSVREYLSNPKSTLFPHEDYKIIMNYYLPIGAPQNSKI
                     KIPNDIVNDGDTHNVIKGFLPLDLSTGRKIRFSEIQYEGIGFTLIDLKNSTFEIKEGL
                     DLKNLLCADDKIKKIQLYKVPILTPTVLTMLEMENNINYIDSGSDLLIRWQVITNFLM
                     ELKKYSNTQTKFS"
BASE COUNT        11608 a         7242 c         5657 g        12444 t
ORIGIN      
        1 ctaagaccat tggtgtcaaa ataaatggaa tgaacatgat cgggttcaac acgataggta
       61 acccaaacat cgttggttca ttaatattga agacacctgg cgcaatcgac aagtttgtta
      121 caaccatata tggtttgttt ttacgtccta ctaaataaat agctaacagt aaacctaaag
      181 ttgcacctgt tcctcctaag ttgacaaagc tgtcaaagaa aggtttgttc acgataaacg
      241 gtgcgctatg tccagctgcg attgcattaa cgtttgcttc aatggctggc gcattgattg
      301 tttgcatcaa aggatcgacc atattcgctc cgtgtaaacc aaagaaccat aagaatggtg
      361 tgataaatgc aagcagtaag gcagatggat aagagtttgc aagtcccata aatggttctt
      421 ggaccactgt atagaaagaa cctacgatat catcaacacc gaatgcagca aaaattgcag
      481 caactaaagc aaacgcagag atagtgatca ttgctggtag taatgaagca aatgcttttg
      541 caactgccgg tggcacacca tcaggcattt tgatgatcaa tttttcattt ccgcttaaac
      601 gtacaaagat ttctgttgaa ataatcccaa caataatagc aataaacaaa ccgtttgagc
      661 tcatacctaa tgctccgcct aaagcgaaga aagagcctaa agaaatcaca cctgcggaaa
      721 caccgtcttt tcggtagccg ttagctaaat gataagcaag caagaaagca atcaagacag
      781 aaagaatggc aaatgtaccg ttccaagcag cagccccgaa tcctttccat gattcaccac
      841 caaaaattga gttcatcaat tcttggaacc cgggaatcgg taagttattg atcattactg
      901 ctaatgctcc taagatcatt aacggcatac tcaccataaa tgagtcccga atcgcaacta
      961 aatgccgttg tgcaccaatt tttgatgcta caggtataaa atgtttctcc ataaatgcaa
     1021 caaatttatc cataaatctt ccctcttttc tttactgtag attacgcgtt caatcgacga
     1081 tacagatcaa tgatctcttt tgctaaatct gtaaaagcta tagatgtcat cagatgatct
     1141 tgactgtgga ccgtcaaaag cgtgacttca acgtgatttc cttgtgcttc ttgtgtcagc
     1201 atctctgttt gagagtgatg tgcttggact aaagattcct ctgcatcttt gattttttca
     1261 tctgctaaag tgaaatcacc ttttttcgca gcagcaatcg cttccattgc atcgcttttt
     1321 gcatttccgc caaacatgat cagacccatg atggcttcta gatttttttg atcttccatt
     1381 tattgtatcc tccgataatt tttattattt gtttattagt ttttctgctt ggtcgagtac
     1441 tttttcacca ttcatcatgc catagtcagc catattgatt acatctaaag gaatgccttt
     1501 aggtgctagc ttttcagcaa attgattttg cataaagcgt acttgcggtc ctaaaagtaa
     1561 aacgtctaca tttttagatt ctagttgatt atccgcatct gaagcagata cagcaaagat
     1621 gtctgcttcc attccttttg cttctgctgc cttttgcatt tttgtgacta ggagacttgt
     1681 actcattcca gctgaacata caagcatgat tgttttcttt tccattttaa acacgttcct
     1741 ttctatactt acacttgtat ataagcaagt agcgtgccaa ctttaaaagc gctttaaaaa
     1801 gttgatatca tcacatttaa ggtctatacc aagttgcata cacactaaaa aagaaagcgc
     1861 acactaaaca cacaaattaa tttttattac cttttttctt ttaacgtgca caaaaaaagt
     1921 tgtgacacaa aacttgtcac aacttttttc aaataaacgg tattcaaaag cttgcatctg
     1981 cggtaataag tccaaccaag ttaaaaacat aagatgttgt ttttactttg ctattcttat
     2041 tacttgatgc aggacagctt tttcacaacc tctcaataaa cggtgttcaa tcagctgacc
     2101 ctgggtatta gctcaaaacg ctggattcac aacctctttt atttcaaata accagtaaat
     2161 acaatgaaca tctacaaaaa acttctattt atttatagat ttcgtcaggc aaatccaatt
     2221 ctctcttatc aatcaaagtc tgataccacg aagcagattt tttcaatgtt ctgcttcgtt
     2281 catcgttcaa ttcgattcga actaatccat atcgattctt aaatgcattc attggtgaca
     2341 cacagtcagt gaatgcccat aacatatagc cttcgcaatt tgcgccttct tctgttgctt
     2401 tgatcaagta atgcaaatgc tgtccgataa attcgatacg gtaatcatct tgcacgattc
     2461 ctttctcatc catatactgt tcttcatatt ctcttcccat accgttttct gttatcagcc
     2521 aagggatatt atgataattt tcttttagat acatggctat atcatacatg attttcggat
     2581 agatttccca tcccctggaa ttattcattt tcttcccagg taaatcaaag acttcataat
     2641 atcgttcagg atggaaaggt gtctcttcat tccattgata acgaggggcg cgaacgcgtt
     2701 taggataata ttgattgatt ccaaggaaat ctactgtatg atgctgaatc gtttctaaat
     2761 cctctgttgc aggatcgaaa taaatcgatt gtttttgaca caactccagg aactcttctg
     2821 tgtagtatcc ttttaccatc ggatcaaaaa atactcgatt ataaaacaaa tcatacatat
     2881 aagcagcttt ttggtcttct ggagaattgg atcgagcata gaccatttca ggatttaaaa
     2941 tacagccaat ccttccacca taatttccgc tgcggtaaat ctctactgct ttagccgttg
     3001 ctaaaacttt atgataattc cacatcatcc acttttttgt gttttgttca tgcggccagc
     3061 gaacagcatc caaatagcaa cgcgtttggg gaacgattgg ttcgttgaat gtaaaccagt
     3121 tttttaccct atcaccgtaa cgatcaaagg caatttgagc atacttagca taaaaatcaa
     3181 ctacttttct tgaagaccag ccatcatatt tttccaaaag aaaagctggg acttcataat
     3241 gttccaaaca aatcatcggt tctacgtctg cttcgatcaa agagtcgatc atttcactta
     3301 tatgctgagc atattcttca tctactatac agttctcata atcagtaaaa aaacgagccc
     3361 aattgataga agtccgataa tgtgtcagat ggatggattt catcagatcc acatcctgct
     3421 ggtattgttc cataaaatta gttgctacgg ctgggccata cccattatgc caaacaaaat
     3481 gttcattttt ataccagcta tctataaacg aatcctgtcc ttcttttttt cctttccaac
     3541 cttccgtttg ccaagcagaa gatgcagcac caagaataaa attttttgga atagtaattt
     3601 tcatgatttc ctcctgtttt ttagatccca tcattttcca cacgatttgc tacttttaca
     3661 aatggcagat agatcaaaat agaaacaata atacaaacaa gttgcgtaat aactgcaccg
     3721 atatttcctg ctgttgccag ataagcattg acgatcggcg gcattggcca agggaccatt
     3781 acaactgctt tcgccgcaaa tcctaaagcg gttgcaaaat aaccaatcgt tccagtgata
     3841 agaggcgtta agataaacgg aatagctaaa attggattca gcatgatcgg cataccaaaa
     3901 ataactggtt cattgatgtt gaagatccca ggagcaaggg ataacttggt gatttgtttc
     3961 atatcttccc gttttccaac taacaatact gcaatcagta aaccgatcgt gactccagac
     4021 ccgcccatac tcatatacat atcccaaaat ggcatagtaa taatgttcgg tacttctttt
     4081 ccagcttcaa aagcttccgt atttacagca attgccgcta aaagcaacgg ttcccgtatc
     4141 ggcttcacca tttgatttcc atggatacca atcacccaaa agacttgcgc aataaacatc
     4201 aatagcaaaa tacccggtaa cccttgtacg acaccttcta atgggcgttg tacgacattg
     4261 taaatgatat cataaaggta cattcctgta agttctttga tgataaatcc cgcagccgcg
     4321 atacccgata cagtcagaat cgtcgggaat aaagcagaaa aactagcaga aacattcgtt
     4381 ggcacggtat caggcattct cagctgtagt ttcttctgtt tcctcaacca gcaataaagt
     4441 tcaatagaaa ggatggagac caacattccc aaaaataacc ctttcgtatc tgtatattgt
     4501 ttagccaata cgttttctac tataacagtc tgattttcat tcactaattc ataaacagtt
     4561 ggattaacag ataaataaga catcactgcg atgataccag ggaatacacc atccacttta
     4621 ttcagcttgg ctaattcgat ccctatcaga aaaacagcat agatggtcaa gaaacttagt
     4681 gtgacatagc tgatggcaga tgcgataggc tttaattctt ctaaaaaacg caagaaactt
     4741 atctgtgcta agccattttc cgagtcaaag accattgctg aaaacaatgt gccaaaagca
     4801 cccgtaataa ttaccggaat caatgcagca aatgcgtttt ttatcaccat gatatacctt
     4861 aaattattga ttctcgttgc cacgttccct aaaacattgg ctaatttatc cataaaactc
     4921 attccagatc ccctcattcc tgcttcttct ccttgacgtc atctcttttt gtctattagt
     4981 cagcgcttac atttcgatga acagaaacta tttactcctc ttttttacca aatataaaac
     5041 aaaaattcat ctgatgtatt tatcataaaa tacatcagat gaactgtcaa ttagtttctt
     5101 tttctcctat tattttctgt aattctctcc gatttattgc catatggaca gtcattgcat
     5161 caaacgcagc aagtgcattc cgcctttcga tggcctgaac gatctctgta tgaatatcga
     5221 tcgtctcgat tttcagatgc tggatatcat aatttttatt aaacaaagca attgattcat
     5281 taatgattgg gataatatgc agcaaggcta cgtttccgct agcttctgca atcatcgtat
     5341 gaaaatcgat gtctaattga acatgttctt gtgtgccttc tcgaaaagaa gtttcaatct
     5401 tttgcgttaa ttttttcatt tggacgattt gattcttcgt tgcatattcc gctgccaaac
     5461 ctgccatctt aggctccaat aaatatctca gttcaaataa gtctcgtatc atccgatcct
     5521 gatcttcaat caaagaaaaa ccgagtgggt cattggcaat ccctcgctta tcactgacaa
     5581 atgtccccgc tccttgccga acttcaagga tattcctgga agctagagcc cgcacagctt
     5641 ctcgcaccgt gcttcgcccc acctctaaat aatcggacaa ttcatattca ttcggcagtt
     5701 tatctcctac ttgcaactgc atttccttta aatatctaag gatcttgtca gtagttactt
     5761 ctactagggt tttattttct tccaaaccac atacctcctt ttcatctgat gtattttttc
     5821 gtaattatta taacacgttt gaatcatctg atgatttttt gtatacaaaa ttgattaatc
     5881 cgttcataga catacaaacg aagaagatat ttaccataaa aaagactagg ataaaattca
     5941 ctcctagcct tcgatcattt ttattttgaa cgacaaaaaa tatgatgttc aataacagac
     6001 gatcttcatt cgattcttga tgtcatcttt tgtttttttt aatatatgga taaaaagttt
     6061 gattacatcg tttctattct agaatttggt cgattctcaa ttcttcttct ggtgagaaat
     6121 ctaaattatc catcattcga acactttctt gtaactgact taaccgactt gctccgacca
     6181 gtacacttgt aacagatttt tgtcgcaaat tccatgcaag ggccatttgc gctaatgatt
     6241 gtcctcgtga tacggcgatt gtttgcagtg ctttgatttt ttccagagtt gatccaactt
     6301 gttcttctga aaggaatggt atttccttac gatgtgctct agaatcttca ggaataccat
     6361 gtagataacg atttgtcagc aacccttgag caagcggact gaacgtgatt gcccctagcc
     6421 cttcttcttc taatactgga gatagatcgt cttctagtag tgcacgagaa aacatattgt
     6481 agcgcatctg atgaataatg aacggtgctt cctttctttt taaaatttca gtcatttttt
     6541 ttgtatcttc tccattatag ttggatatac caatatataa tgcttttcct tgtcttacaa
     6601 gttgcatcaa agcttctgct gtttcttcca aaggtgtatc agggtctggg cgatgatgat
     6661 agaagatgtc aacataatct agccccattc tttggagact ttggtcacaa cttgaaatga
     6721 tggatttacg agagccccat tccccatatg gcccttccca catatgataa cctgctttgc
     6781 tagaaataat cagttcatca cggtaggctt gaaaatcttc tctaaaaata cgcccaaagt
     6841 ttttctctgc agctccagca gggcctccat aattattcgc aaggtcgaaa tgggtaattc
     6901 ccatgtcgaa tgcgcctctt aaaatctctc tttgattatg gataggatca taatcaccaa
     6961 aattttgcca taatccgaga gataaaatcg gtaatttcaa acctgaatga ccggatttac
     7021 gatattccat tttttcataa cgtgcactat ctgcaatata caatttttct cctcctcatc
     7081 aaatcttttt aaaacgcttt cttttttcta tttttagttt actacatttt aaagaaaagg
     7141 agttaatcaa aatgattttt tcgtatattt ttttgccatt tgttttttac tcgttgatag
     7201 atcagaaatt gattacgtgc ttgctggatt tttttataac gtttcggttg ttttttgtaa
     7261 aattgctgat gatagttttc tgctggccaa aacgtaccgg ctggttcgat ttttgtgacg
     7321 attggttggt ggaaagttcc tgaactgtct agtttctgtt ttgattgttc cgctaattct
     7381 ttttgtcgtt cgacttgata aaaaatcact ggacgatatt gcttccctct atcttgaaat
     7441 tgtccaaatg tatctgtggg atcagtaatt tgccaataga ttgtcagcaa ctcgctataa
     7501 cttatttctc ttgtgtcata aatgatctcc acagcttcca catgacctgt gtaaccacca
     7561 cttacttgat cataatttgg tttttcaaca tgtccgcccg tgtatcctga caaaacagat
     7621 aggatccctt ttttcgattc aaacggctcg accatacacc agaaacatcc ccctgcaaat
     7681 actgcacgtt cttgatagtc agcatcttgc atggcatgct tggaaaagtc atatttttgc
     7741 tccttatcaa atccttccgt aatcaataaa taaaagtcca ttacatcagg cgtcagattc
     7801 attcggatag ctaatggacg tagtgttgct tctagttttg ataactgttc tttaacggat
     7861 atattttctc ttatgtcatt ctttgtctga atcaatactt ttcgttccca atctcgtgta
     7921 ttcggattca aaatcagatt ataaagtgtt tgaatgaata tttgttcctc atccatagat
     7981 tctcctcctt tccgaagaag acaagctagt gactttagct gtaatttatc ataaagtgag
     8041 gaaataagcg attacttcat ccccctacag atttttcgta taaaaaagag agaatcctta
     8101 tcgacagatt ctccttttta atcaatttat tttataaatg aaaagttaat ttacctttta
     8161 tggaaaacta ttttaaaaaa taaacataaa tatgcagtta atgtaacaag ataagaaata
     8221 atagtcgtta ctgtataact tgtgcttact ttaatatcag caactccttt gactccgctt
     8281 atttgtacca atccattagc attcacctgc tcctttacag gttgatgatt tatttctaca
     8341 ttcgttccta aataagcata tacaggaagt gtgattactt ggctcttctc attagttact
     8401 ctatatatga tagaactacc agttgtttta taaggaaggt ttacccattg actgccaatc
     8461 tttgcttcgt gttttattat atgctcctta ttctccaatg aagcgatagg agaataatca
     8521 tataaaaaat aatccattcc tttagtggta tacgcctcta ctgtttcttt gtttacaaca
     8581 atatgtcccg gctgagaaat tattttttga ttgaaatttt ttttactaga aacagttaaa
     8641 gtgattaata acaaaacagt cataaataaa taaaatagtt ctcttgtctt attgtatctt
     8701 ctatttttga aaaatatcat cgttaatatc agagaagaga atattatttg caagcttaag
     8761 atccgccaag gaaattgtaa caatttggct ggcgtatttt gcagaagata ccatggcacc
     8821 aaactagttg tagctagcca agtcaaacac gtaccataat aaatcttttt ttctatgttt
     8881 gttaattttt taaataaaat caggggaata cataaagata acagaccaac tagtcccatt
     8941 gagtaagtag ttaagtcgtt gttcatagct tcagtcagac tatcgaacac attagatgca
     9001 tgagcatata aatttgtcac gctaggtttg ttgatttttt ggtagagcat ttgttcaaac
     9061 atcggatacc aaaaagcact cgtcagaacc aatgtcattc ctgccgcact aaataatttt
     9121 ttaaatatag caataaaatc tgcattcttg aaacctttag aaaccaaacg aataaaaata
     9181 aaaatgataa ttaatgctgt actcattaat gttgatagta catggctgta cactagcaaa
     9241 ctcatactca atgctagctt tacagacgga tacttttctt cttttccaga gatgatttga
     9301 taagcataaa ataatacagg gataacaagt gttattgcga tagcttcggc aattgcggaa
     9361 cgatagtaga tgtctactgt ccgataagca gagaaaatat agagacaact aaataaaaat
     9421 gccgcttttt tttgttttaa aaaccgctcg ccataatgat aagctacgag tgttgtacac
     9481 aagttcaata accaaacgta aataatatag cttacaatca aattttttgt catccaatat
     9541 aacattacag ctggaaaaaa agtcagaaag ggataaaaat aatttacacc atatccagta
     9601 taattgaatg tctcataatt aatcggactg gtaaaaatag tcgataaccc cttgattcga
     9661 gataagtgaa aagaaagatc tccagtggta taaatactct gtgtattttt gaaaaagatg
     9721 aaagaatata tactactaac tataattaat ccactcaata ttactacttt tttatttatt
     9781 ttcattcttc ttgtttatct cctttttagt cacatatcga gaatctttca acttattagg
     9841 tgcaaatcgt ttaaaacttg aatacaccac taaacaataa gtcagaatac tgatccataa
     9901 agccatgaga gcagttggag tatattttgt tgtaatttct atcttatttt ctccagcatt
     9961 tacatccaca ttcactaagc catgtttttt ataagagtca tttacgactt taccgtttac
    10021 ttttacctgt gtacctaaat aagcatatac tggtactgtc actttttgct ttttgttgct
    10081 tgccactgtg taagtaatgt tattatctgc agctttatac ttcccttttt cccacgattc
    10141 tcctactttt acttcatgtt tttctaagtg aggcctttct tttatcgctt ctgttggggc
    10201 gtaatcgtat aatcctccca tatctgatgt tgtataacgt gggagtgttt cttcattgat
    10261 aacaatatga ccgtgttttg attggataac ttttgcgtaa ttttcttttg ctgctataga
    10321 cgtgacgagt agaaacacca cagtagcgcc aatgattaac catgaatatt ttttattcat
    10381 agtctttttc ataaaaacaa gcgttatgat cattgaagaa aaaaagattt ggatacctaa
    10441 gatacgccaa ggaaactgga gtaagcttat cggtgttttt tgaaacaaaa accatggaaa
    10501 taaattagtt acgcataccc atgtagaaac tacgccaaca tagatgattt tttctttttt
    10561 ctccatttct ttcagtatga ataaaggaaa aatcaacgca accaatccta ataaccccat
    10621 agtgtatgtt gtaatatcgt tatttaacgc ttgaatgata ctatctgaaa tagaaagtgc
    10681 ttctagctgc aaatctgttt tgaagggact gtgtatttct tgataattca tctgctgcaa
    10741 cataggatac caaaaatagc tagttaatgc acaagtcaaa aaaacagcct ttactaaatt
    10801 cacgaccaca aattttatat cgttttttat ttgcttgctt aaaaacaaac gaactataat
    10861 catacaagca atcaatgcac tacacaatag tgtagttaag acatgagtat acacaagtag
    10921 acttatactg acagataaag cgatgacttt tttttctcta ttgaatatca atccataagc
    10981 ataatataaa acagctggga taatcgtaag agcgattgct tctgcaattg cggatcgata
    11041 atagatatca actgttcgat aagttgcaaa agtatataaa caactaaata aaaaagcagc
    11101 atctatcttt ttaaaaaact tttctccata ataaaaacta atcagaatcg tacaaatatt
    11161 taataaccaa atatatagaa cataacttaa tattaagtta tttgaaattc cataaaaaac
    11221 gactgcagga attattgtaa gaaaaggata aaaatagttc agtccatctc cataattgtt
    11281 aaatgttgta tagttgattg gcccttcaaa aatagaagat aaccctttga ttcgtgaaag
    11341 atgaaaagat aaatcacctg ttgtataaat ttcttgagca tttctcataa aatttactga
    11401 atataaagta ctaagtaaga taagaactac taaaagaaat gcttttttac ttattttcat
    11461 agatttgttg ttctcctttt ttaattctat tttcagtata ctagaattgt ctttttttaa
    11521 taagttttgc gttaaatttt tcatagcact agtatgatat actagaaaag aatcaatttt
    11581 tattactttt aaataggaga aaaaaatgaa aaaaaacaaa aaccaaataa tagatatcat
    11641 ttttatgtta tttctaagtt ttgcttacgt catccctcta ttcatgtcta agggaatcta
    11701 tcatagtgtc aatcaggata cttactttca tttatctcga atcataggac tagataatgt
    11761 atggagttct ccagtaaact tcaataactt cgatcatcat ggaacaatga tgaatatttt
    11821 ttatccatgg cttactcttt atccagcttt tttattttat aaaatgatgg gaaatcttgt
    11881 tttaagttat aatatctact atttttttat cactttttta acaatggtcg tttcttattt
    11941 ttctatgaaa caaataaaaa acaatcgtta tatttcgctg ttattttcga ttatttatac
    12001 attttccgcc tatcgtgcca ttgacatatt ccatcgtgct tcattgggag aagctgtcgc
    12061 tttaacattt ttgcctttga tactaatggg gtgttacgaa atttatatta gagattacca
    12121 aaaatggtac tggttgtcta ttggcatgac gctagtagtg tatactcatt tactttctgt
    12181 cgctatggtt tctgtattta ttggaggaac gttgtttctt tctttttatt tttgggacca
    12241 aaaaatcgct agactcttaa gtcttttaaa agctaccgtc ctcacctttt ttttaagtgc
    12301 gggattctta attcctttta ttcaacaatc tagagcacaa gaattgaaag tcccactggg
    12361 aaaagaatta agtggtatgg ctcctagtga tatgctgaca catattttaa ataataacta
    12421 taacaactat actattggat tattcttatt tctcggattg attggtgctt ttatttttat
    12481 aaaaaaatta actgctgatg atttatttat tttctttctt ggtgtatttg ttcttttttg
    12541 ttcaaccaat ttatttcctt ggcaactttt taaccataca ccagttaaga gtctacaatt
    12601 tgtctggcgg ttaaatggtt tttcttcttt atttatagcc tatacgatga gtatagtgat
    12661 ctattatatt ttttctacta aaaataattc atggaaaata atggtcttta cgtttcttgc
    12721 actaatattg catctctcag gagtaagcaa ttctatccat gctaacaaag attcattaac
    12781 acttatagca cctgaagacg ctgttgctat agctgaaaat tacaatcata ctgattatgc
    12841 aaacaaagag tcaatctatc atcctgatat gattaataat gatcaatatt tactaggtaa
    12901 ccaggaaata aatccaacaa ctcattttat gagtaacaaa cttacaattg aattagataa
    12961 ttcgaataat aaaaatactg tcttgacgac acctatttat cgttataaag ggcaagtggc
    13021 ttctattaat ggcaaactag tacaaacaaa attatctaag tttggcacaa ctgaattaac
    13081 tattcctcca ggtataaata aagtcgttat tacttatcag tacacaaaac tagcaattgc
    13141 ttcaagatat ttatctatcg ttactttgat tttattttta ctttatcgat ttactttttc
    13201 taaacaaaaa caaccgagaa gagaagtaca acattctcac tagattttta tttaagaaag
    13261 actttttagc tgtacacata aacaggctaa aaagtctttt tttatatttc tttaatttgc
    13321 ttcatacatt atttaacatc gatatttata ctgtgaaaca tgcgtttcat ccattatcaa
    13381 agtattttta tcgataataa acttcatcca aaaacagacc ttgtgcaggg acggtttctc
    13441 ctgcatgttg ccgcactttg ctttcaaata tttcatcgat tgtttctatc ggcatggcac
    13501 ctgtgccgat ttctagtaat gtccccatga taatccgcac cattttatat aagaatccgt
    13561 ctccgacaaa agtaaaatga agcatttctc cctttcgttc gatagataat tcatcaatcg
    13621 tacgcactgt ggattttttt gattttttca atgcagaaaa accaatgaaa tcatgtgtac
    13681 ccactaattt ttcgcaagct gcattcagct tgtccatatc caactcttga gggaaataaa
    13741 agctgtggtt tcgctcaaat gctgaaggaa tcacgttgtt ccaaacataa tagctgtatt
    13801 ttttgcccac cgcattatat cttgaatgga agcgctcagg catttcttcg attcttttga
    13861 tgacaatatc ccgcggaagg taacgattca taaagtcgat catttctgcc agtccaattt
    13921 ctgtgtttgt tttaaaattt gctacttgtc ctcgcgcatg ggtgccagca tctgttcttc
    13981 ctgatccaat aatttctatc tcttcatttg tcatctgatg caatactttt tcgatttttc
    14041 cttgaatggt tttatcgtca tctccaagtc tttgccatcc tgaatatctt tttccgtcat
    14101 attcgattgt caacttgatg tttctcatat tttagtggct cctctgtctt ccatttggtc
    14161 ttctctctac ctttttaaga ttgtagcaca aaatatagct ccttgcttct ctaagacaga
    14221 agctatacaa gaaaactgtg gaaatatata tttcagaaaa acaaaaaaca gccaccggat
    14281 gaagtatccg ctgactgttc aatttgacgg ctcaagtttt actgtttgag atgcaagata
    14341 ctcaaccagg caatgggcac ataattaaag aaaaaactga ttctttggca aaaacctatt
    14401 ttattcagta atggccaaga atttatagaa ggaattcttg ccagtccata aatcgccgca
    14461 aaaagcaaac tgatcacaga cagtccaagg tataagtggc ttacgtccat ttgcccattt
    14521 tttcgataga tcaagaaaag aagaactgga aacaataaaa aaccactgta acctaaacct
    14581 gatccgatat tatggaccca tgtcgagaca ttccacgaag attcatgggt attgatactg
    14641 aacaaacctg taaagataca atcacctata ccatagaacg cgatggctgc tgtaactagg
    14701 gtagctaaca cacgagatgt actaacaaat gcagcataca atgcaggcaa tgacaggatg
    14761 aaaaagatcc ctgaaaccac agaccaaata agaaacgctt ttcttacagg actggaaacc
    14821 tctccaaata cactgatcac gctcttcatt tgatctaatt caggataata caatcctaat
    14881 acgtacggag tcaaaaaatc actcagcacg cctaataata aaaagaaaaa accaaattta
    14941 cgtaaaaaat ccatgatacg cctccaataa caattaccta tgcttttaat tgttattata
    15001 aacgacttta tcttgattta acagaaacct ctatttacac gaacatctat ataactcatt
    15061 aaaaactcga atcattttaa aaatactaaa tatctaacgt tcaacgttca cttaatccat
    15121 ctaaacaatc tttcaatttg attttttccc cacttctttt acgcgcgcct agctctccta
    15181 ttgcagtaaa caacagatca cttgacgaat ttaaggcagt ttccattgaa tcctggataa
    15241 caccgataat aaatccaata ccgacgattt gcatcgcgac atcattagag ataccaaaca
    15301 aactacatgc taatggaatc aataacagtg aaccgcccgc aacacctgaa gctccacaag
    15361 cagctaaagc agacaaaata cataaaagga ctttcaaaac aaaaggtgct tcaatcccta
    15421 aagaatgtac agcagtcaac gtcatcaagg aaatggtaat cgcggcaccg cccatattga
    15481 tcgtagcacc taacgggatc gatatggaat aagactcttt tgtcaatttc aatctttcag
    15541 ccaacatcat gtttatcggg atatttgcgg cagaacttcg ggtaaagaaa gcgggaagtg
    15601 cgctttcttt caaacaaaag aaaatcaatg gatagggatt ttctttaata aacaaaaacg
    15661 tgaggaatgg gtacacaact aatgcgacaa acagcatcgt accgatcaaa acaagtaaaa
    15721 gctgcagata ctctgccaat ccagcgattc cagtcgtagc aattgattga taaaccaatc
    15781 ctaaaatccc tatcggagca aatgcaataa tcacttgtac gacttgtgac aacgctatag
    15841 atatctgatc caccaactct tttgtcgatt ctgaacgtgc tcgaaaagct agtcccaaca
    15901 atacagccca gaataagacg ccaaggtaat tcgcatcaat aagagattga acaggatttt
    15961 gtgtgacatt cgtcaacata gtagataaaa cactttccaa actttgcggt gctttttcag
    16021 atactgtttc ttgtaaagta ataggaacag taaaaattga acttacaata actgctacaa
    16081 gtgcagaaag caatgttccc actaaatata agatcaaaat aggcttcacg aatgtcttat
    16141 tcccaatttt atgcttggca attgacgcca tcgtcaagaa aaaaaccaga ataggtgcga
    16201 ttgccttcaa gcaactgaca aacaacgttc ccaatattga aataaatgtc catgtgggga
    16261 aaaagatacc aaacaatatt ccgactaaaa taccaacaac aatacgttga actaacgaca
    16321 tatccaaaaa cttctctaac aaatgaccac cctttcacaa ttttaacaat cattgtatca
    16381 ttttatgcaa agaaactaaa ggtataattt tctaaaaatt ctaacaatac aaacaaccat
    16441 ttcttgctaa ttttgtactt tttctgtcta cacgttgttt tttgagatat tctaagttag
    16501 gatgttatta atgggcaact tatcaggaaa cgttttctta tgtttttgtc caattttttt
    16561 gtgaggtgtt tattcttgaa aaaaataaag aaggagagtt atggcttcct gacaatcttt
    16621 gtcgcttgta taatgatggt tttacagcgt atattgattt cagcagtcac tattcctaca
    16681 tatgcaacaa accctggtcg attctacatc tatacatttt tacaaacttc cgttgttatt
    16741 ggtgcaaatt tgatcccact ttacatgggt taccaatatc aaaaaatcgc ccgtttaaaa
    16801 gttttacatt atttaagtcg ttttgccttt atattcctaa tagccacact agtttgcaat
    16861 atcttttttt acgtacaagc tggcagcttg aatattcgtg attattggct tatcctaaca
    16921 cctatcagtc agaattactt tacttatgct gtttcttgta ctttgctttt ttgtagtatt
    16981 ccttatacag ttggattttt aaataaatta tcgaaaacaa caattaaata tctactatta
    17041 tttttaacaa ttggattagt tggctgctct actctattta ataaagaccc gtttgcatta
    17101 cagaatggac agagtatttt atggattttt tatttatttt taatgggtta tggtttgaaa
    17161 gaatggaact ggaaagaaaa ggtccgctat aagcttcctc aagtatttat cagcttgatt
    17221 gttttattcg gtttgattat tttgatgaca caaatttcac tcatcatcag aggaaataca
    17281 gatacagcgc tgaggttttc taaaccatat tctctcttcg caatgtatta tactttctct
    17341 tcgtttttat ttttagaaat gctatctgat aaattaggta taaaaggaag aggaaatttt
    17401 cttgctgtat ttttgattgt cactcaagtt atatgtaatt tccctttagt ttcttatcgc
    17461 gtatctacat ttatgaaacg tgaatttcca aactcaggga aggcatggct gataaatatc
    17521 gggcagtttt ttatttgata tttattagca gtgtccctcc tagttatctt tttattttat
    17581 atacaaaaaa tccgtttcat tcatcgtttc atcgaatact tcgcttttga ttcgattgaa
    17641 caattaactc agcgttggaa aaaaagaatt cattggcttt ttgttcataa aagttatttt
    17701 ttagttgcag cattttttta ctgctttacc ttcgtgcaga ttttcgtttt agaaccaaaa
    17761 gaaggttgga aagaaactat ccaggttgcc ttaaaaatat ttactcagcg acaagcaccc
    17821 atgatcctga caatcatcat tattatggga tttttcttct tactattgtt gatttccaat
    17881 cgtttttggt acgccttgac tgctaccttg atcattaact tactgctcac tatttcgaca
    17941 gtaatcaaaa tggaaatgcg ggaagagcct gtctttcctt cagatttaaa aatgctgacc
    18001 ggattgtcag aactattatc gatggttagc ccagtcttat taatcgtggg cggattgatc
    18061 cttctcctat tattgattac tagtattatt gtacaacgta gactacaaaa acagtattcc
    18121 ttgaagattc attggaaacg tcgatttatc agtatcgctg tattattagg atgtttttcg
    18181 ggtgtctttt tcattaatca caaaaattcg ccttctttct tgctgtttaa tttatttaaa
    18241 gtaaacaaga ctttctttaa ccagcaaggc gccgtaaaag ataacggacc agtcattcaa
    18301 ttcctaaaca atatcgacat taaaatcatg gaagaacctg ctggctattc gaaagaaaaa
    18361 attaatggaa taatgaaaaa gtacaacaca aaggcagatg aaatcaacca aacaagaagt
    18421 gactggttaa acaatcagac gatcgttctc aatttaagtg aaagcttcag tgatcctgca
    18481 cgtgtcccta atctgacagt acctacagac cctattcctt acatcaaaag cattataaca
    18541 gaaggaacag gaggattgat gttatccgtc ggttatggtg gcggaacagc taacatggaa
    18601 tgggaaggac tgacaggctt gagtatcagt aacctgtctg cttcgttagt tacaccttat
    18661 acccagctag tggagcgtca gaaaataagt ccaaatatta ccgatctatt cgatgaaaaa
    18721 atagccatcc atccttttac agctgctctt tatcgcagaa aacaagtgtt tgataaattt
    18781 ggttttgaca ggttctatta tttagacagt ccggataaat taacttatac ggataaaata
    18841 gaacaaagcc cacgcatatc ggatgattca gcatacaaag aaaccttgaa agctttacaa
    18901 agcaatacgg aaacgtcaca attcatccaa ttatccacta tgcaaaacca tatgccttat
    18961 gatgattact atagtgaatt gaactacact gctgaaggaa ctgctgtcat tcctaataga
    19021 agaaaagaat tacaaactta tatgcaaggc cttcactata ccgatacagc agtaaaaaaa
    19081 ttcatccaag aaatcgacaa aatcgataaa ccgattacct ttgtttttta tggtgaccat
    19141 ttacccgcaa tctatagtgg gaatgattcg aaaaaatatg gattagaaca gcaccagaca
    19201 gattatttca tttataacaa caagtatagt cgtgaacaag cagctacgtt aaataaagaa
    19261 gttgttgctc ctaataactt tggtgctatg gctcttgagc atgcgaatat caaagtaact
    19321 ccttactatg cgttgttgac agaagtatct aatcatctac ctgcattaac aattgatcct
    19381 acagaaagct tgtctaatcg ttttaatgga aaacaggtct ttgttacaga ggatagtcaa
    19441 attatccaag aaaaaaattt aactgagaaa caaaaagaaa ttctagaaga ttatcgtctg
    19501 atacaatatg atcttgttgc aggtaaccag tacagtgcaa catgggcgac acaaaaaata
    19561 aaagactaac aaataaactg agcaaggggt tgtgataaaa gacatgtcac aaccccttgt
    19621 ttatctcatt aatttgcttg tccataaacg atttgattaa agccattttt caattcatta
    19681 ttcgctgtct cgttgaagta aagataatta tcgggattcc cctgattttg ttgtgtcacc
    19741 aatacttttg gctgattttg ctgaaacccg aatagataga cgtgcttttt cagttatggt
    19801 tctgtctctg catcggaata gacggctgtg atttgatagt ctgcttgacc tgtcccactt
    19861 tctgaccatt ctgcagaaac aggcactcca ccaatagcca tcttccactc cccgttcaaa
    19921 atagcttgag ggactttaag accatataag tccacactca tttgattcgt ataacttttg
    19981 tattgttgtc ccattgtttg gccccatttg gtcataaatg cctctaattg tgcggatttg
    20041 tctgcattcc acagtgtttg ttcaacttgt tcgctgcttt ctgaagagga agatgaagcc
    20101 tctacagaag aacttgaagt agatgtttga gttgtttcag tcgttttgga agactctgac
    20161 gaagtagagg tatctgctgt ttctgtactt gctgcagttg acttgctctc tgtgctagtt
    20221 gttgtagtag ttgcaactgt tgctttcgct gtttcttttg ttgattcttt tttcgattca
    20281 ttcccgttgg tacaaccagc taacaaaaaa gctagaccaa ttgttactaa aatccttttt
    20341 ttcaattaaa aaactccttt cgattactcc cacttcttta ttctatcaaa taagcaatgt
    20401 gattttattg atttttcgta ttttctcatc aatctttcaa atcttctaaa aactgagaag
    20461 cacccgctga tgttgtctgt aatacatcag cgggtgcttc ttttatttta atcttcgtga
    20521 ttttccaatt tacctcacgc tttatatttg tatttgaaga aacatagact tttagtcatc
    20581 atcgtcttcc tcatccaaat cttgtcggac agtttttcct tggagtcttt gtacttggta
    20641 gatgatttct ttattgaaac ttaaaagttc aacaagcaat tgttgcaagc catatttttc
    20701 ttctttttca gctaatttga ttgcccgtgt gataaagaca ttttggaaat caaaatcttt
    20761 tgcaaagttt tccaacattg ttgaggctgg taaatatttg ttttgaccat gttcgtaaat
    20821 ttttccataa cgcatgactt cttctaaagt agacggaacg atttcatttt caatcactaa
    20881 ctcatgagag attttattga accatctcgc ttcttgatca gcatattctg aaaaaagggt
    20941 acttaattct tgcgaagatg tacccaaaac atacaattgt gcttggatca atttcatttc
    21001 ttctaattta aaatttgcta atacatgccc caccatggcg ccagcagttg gtttatgatg
    21061 gtcgatatct gcttgttttg tttcttgaac aaatttttct tccactatat tcattgattt
    21121 acgcctcttt tacttttgct gattggactt cataacctaa tttttccaca actgcagcta
    21181 attgttcagg gtggacttca tctggatcaa agtttgcttt gattttgctc gcattaaaca
    21241 aaactttcgt attgcttacc ccaggctgtt gagaaaccgc atgttcgatt ttttgcatac
    21301 agcttggaca agctagtgta tctaattgca taataatttt tttcatcgta gttcttcctt
    21361 cctttttctt gatagtctta ttctagatta cagcttccat aaaaaaattg attcttatca
    21421 agttttacga tttttcttct ttgctttcgt gtccaaaata caataaacgc atcgcgttaa
    21481 agataacgat caagatacta gcttcgtgaa cgaacatccc actagccatg taaataaacc
    21541 cggcaaataa gccgttgagt aaaaataaga cgacaccaat ggcaatcact acattttcac
    21601 gggtatttaa aacagttttc ttagccaagc ggtaggcatg aaccaacgat tcaaaattag
    21661 attgcatcaa gacaacgtca ctcgtttcga tagcaacatc cgttcctgat cccatagcaa
    21721 tcccgatatc agccgcagcc aaagagggag aatcattgat tccatctcca ataaaagcaa
    21781 cgcgcaatcc ttgttcttgg tattttttca caaattgaac cttttcgtct ggtaataatt
    21841 cagcatggac ttcatcaatg cctaacatat cagctacata atcagcagtc atctgattat
    21901 cacctgtcag catcactaac tgttttgctc ctgcttgttt caacttagct aattgttcag
    21961 cgacttctgg tcgaatcaca tctgacacac ctatgatttg agtgattttt ttgtcgattg
    22021 ctacaataat gaccgagctg cctgtttgtt gtaattgatg taaatcttgt acttgctttg
    22081 gtgtgagaga aagtttgtga gcggcaatca atttggtgtt gcccgcacaa actgtatgac
    22141 catcaatctc agctgtgatt ccttgtccct tgattgtctg attatctttg actgctaatt
    22201 gttgaaaatc aatgtctttc tcctgagcat aatggatcac ggcgcgcccc agaggatgat
    22261 cggataacgt ttctaatcga gccactaaag ctaagctgtc cccttcatcc tctgtatagt
    22321 tcttgatagt ggatacagca gtagttcctt tggtcaatgt accagtttta tcaaagacaa
    22381 aagtatcgat tttggaaaaa gtatccattg cttcaccgcc tttgactaag atgccccgtt
    22441 tcgctccatt accgattcct gctacattcg aaacaggcgc accaatgact aaagcgccag
    22501 gacaaccaag aaccaaaaca gtgattgcta aacgaaaatc acgactaatc agaccaacaa
    22561 ccaacgcaat aagtaaaacg gttggagtat aatactgaga aaatcgatca atgaattttt
    22621 ccgcatggga tttggtatct tgtgcttctt ctactaattc gataattttg gcaaaggtcg
    22681 tatcatctcc gaccttagtt gcttcaatcg tcacgtagcc atctgctaaa atcgttccag
    22741 agaagacttc atctccactg attttgacga cttgtcgtga ttcaccagtc actgcggctt
    22801 catccgcata ccctttcccg tcaatgactc gtccgtccac aggaatagct ccaccagttt
    22861 ttactaagac gatatcgcct tcttccacgt catcgatttc cacttcttca gtcgttccat
    22921 cttcttggac aacactagca gtagatgggg ccatctcggt caaagccttg attgactccc
    22981 gcgttttggt caatgttttt tgttccagat agctaccaaa caaaaacaag aatgtaacga
    23041 tagctgactc cttgtattct ccgatcataa aggcaccaag cacagcaata gtaacgagta
    23101 aatcaattga gataactttg actttcactg cctgatacgc atggatcata ataggtatga
    23161 ccgcaataat agaagctatg gctagagcaa tgttatagaa caagacaaaa ccagtaaatt
    23221 ttccgataaa accaaaaata atcaacacag ctgataaggc ggtgatatga tttcgatgct
    23281 cttggatcca cttttgtaat ttcatctttc tccctctttt cctttcattc ttacgagact
    23341 aagtatagat acttatccat cataaaaaat tgaccactat caagtttagt caaaaaggcg
    23401 gttttctttt ggtagaatac actacaaaaa atagttagca agaagactca ctaaaagtga
    23461 tcttgccaac tattgtcgtt tctatcgaaa ttttcattga atgattttcc tgtacagcat
    23521 acatcggaga tctatttctt tatctaagat ttttatcttg ctaatttttt cctttagtct
    23581 ttcaaatcca cgtcgttcat agaattgata cgtacagcca ctatctgtaa aaaggaatat
    23641 ttcttttcct ttctctcttt tttcaaattc tgttagcaac ttggtaccga tgccttttgt
    23701 tttcaaatca ggatttgcag ctaaaaaaat gatctctcca tctggcgaat gcttctttaa
    23761 atatgctgca agcatttgtt catttgctgt ctcgtaagct cctttacttt ctttagcaaa
    23821 tatattttgt aaaaaatcga atatcttaac atatatttgc tgtccaaaag aacgatgttt
    23881 ctttttttct ccttttatct ccgccagcaa aacacctgcc aactcgtcct ctgcatacaa
    23941 agcaagaatt tgagttgctc gattcaactc catatacaaa aaatatcttc cgtaaagatt
    24001 cagcagaagt tcattttcca tatatctctc aaagttcatt ccttcaacag caaaatagat
    24061 agcttttttg taatctttct tttctaaggg tttaaaagtt agtttcatca tttcgcctcc
    24121 tcaacttcaa tgattgtgtt atacttacat tataatagac acagtgtcta ctatctataa
    24181 tcaatcatct ataagtttgt cgattaagcg acagctttgc tttgatatgt cggataagga
    24241 gataggtaaa tgaaaaagac agatagacgc gtcaaaaaaa cagaaaaagc tttggctgaa
    24301 acactatcca cattattagt aaataaaaag attcaagcaa tcactatacg cgaactaaca
    24361 gaaacggcag atgtacatcg ttcgactttt tatacacatt ataaggatat ctatgatcta
    24421 tatgatcaat tagaaagcaa cttttttcgg gatctaaatg aaattctctc ttatgatcca
    24481 gcccatagct atgaggaact atacactcgc ttgattgact atgtttacgc aaatactttt
    24541 ttatatcgct tatttatcct caaccatggt gatatttcgt ttcagaagaa agttaaacaa
    24601 gttattgaag aaaactatct gaacatatgg ctatatgaag acaagaaaac gattatcaca
    24661 gaagaaatga gattctttac tacgtaccac gtccaaggtt gtctatccgt tctcaatcgg
    24721 tgggtagaaa gcaattacaa gtactccaaa aaagaattat tagaactctt acagaaactg
    24781 aatgatcaca tagagaaaat catgccttga ataaaaacat actaagctta gttaagaaga
    24841 accgtaacct tctcgtataa caactgaatc ttatttagcc aaattgttta ctgaagattt
    24901 tttgagtaaa atttctataa ttcctactta ttgaaaagta gtttgtagtg ctgcttctcc
    24961 ctctctaagt gatatatctt gttgtaccaa tcaaattcac ctcatcatta ataaattact
    25021 tttaggctaa tttattacaa cttataggtt gaagctgtaa ccaatttata gtcatattat
    25081 atttttatca tccagtttat tgaattcttc tcgtttacct caattcattt taaaggggaa
    25141 tcagctcatc atctaacatt ttacgccatg ctcgcttcat ttcttgtggg tatttaaatg
    25201 gtttcgcttc tggatgtttg gctttatatc cttcgtaatc cttactgttg ataattgctt
    25261 tcatattagg aattggatct tcacctggca tatattgcag attagaagca tgtaattttt
    25321 tctcagaaac aaaccactca ttggaaaaga catgaatcaa atcatcactt acttgtgtaa
    25381 aatagcgacg tttaatgaca aagatatctt cattgctatc tagtgtacct tcatttcttt
    25441 gtgcttaaat tcaaagataa ttttctcaat aaagattttt gattccagta agattccttt
    25501 actcctttta caacatagcg ttgtcctttg ttttgaaaca tcttcttccc ctctttgcca
    25561 ttaaaaatag cccaattctc tataaagaag attaagcttc attattataa tataaagttt
    25621 aaatttggtt tattacttac tttttcttat tctctagtaa gctaatattg aaaaaaatgt
    25681 aatcagatca ttatttttat atgttgtaac ttcctgataa gaaaactaat taaaagaaag
    25741 aggtaactac ataaactaat taaaaaagct aacttcatag ttggaggata aatggaagaa
    25801 acttcaatga ttgtttctcc ttgtgttcct tcaatcgaca ctagtcctat tatcaatctc
    25861 tcttttttgt ccatttactt ttgcgactgt tccccaataa tcaaatacag gaagcgttat
    25921 tttttgtcct ttagattcat gtactgtata gactattttc gaatccatca cttgataagg
    25981 catagtatgc cattccttgc caattcttac ttcatgattc tgcaaatgtt ctttgtattg
    26041 taatgcttcc gtgggtgcat agtcataaag tcctccggga aggagtgtcg tgtaacgaat
    26101 aagattttct tgattcatta ccaagtgatc tctctgagtg acaactttat gttcatagtt
    26161 tgcttttgtt gcagcagata cagccaacag taataaaaca attgccgtta tattaactac
    26221 ttttctttgc ttagctgatg tgctcttcat gaaaacgaac gataaaatca acgagccaaa
    26281 cagtacttga aagcctaaga ttcgccaagg aaattgaatc atttgaatgg gtgtattttg
    26341 taataaagac catggaaaaa atttggtgga taagagccaa gagactaccg cactaaggta
    26401 aatcactttt tctttgcgat taaatccttt aaaaaagaag agtggacaga tcaaagaaat
    26461 aataccaatg attcctaccg taaaggttgt caggtcatta ttcatcgcac caatcaaact
    26521 atccgagaca tttaatgctt ggtgttgtaa ggtcgtttta tctggctcat taatcgattg
    26581 aaccatgatt tgtcggaaca tcggatacca aaagtatgct gttaaaagaa tcgtcattcc
    26641 tactgccttt gacaactcca caatcaaccg gatgctttct ttttttcttg tttcacttac
    26701 tacaaagccg cctaagacta gtaagccaac ggctattaca ctcataaaag tggaaagaac
    26761 atgtgtataa atgagtaagc tcatactgac tgctaatgga attgcacatg gctttttctc
    26821 ataaatcagt gcgtaagcat aatacataac tatcggtata accgtaagtg caatcgcttc
    26881 agcaatagca gaacgatgat aaatatcaat cgtacggtac ccataaaatg tatataaaca
    26941 gctaaatata aaagccgcat cgattctttt taaaaatttt agtccataat gaaacatcag
    27001 catgatagta caaacattca atagccaaac atataagata taactaacga ttaaattatt
    27061 acttatccaa taaaaaatga ctgccggaaa aaaggtcaag tagggataaa aataattcac
    27121 tccgctccca taatgattaa acgtcgtaaa attgattgga ccagaaaaaa ttgaagataa
    27181 ccctttgact ctagcaaaat ggaaggcaat atcccccgat gtagaaatag tatgaacatt
    27241 tctaaaataa ttgattgaat aaagtccagc aataattgct aggagaatgg acaatattat
    27301 ttttttcttt acttgcatta cttaattata tactcctttc atggattgct ttatctagta
    27361 taacttaaat tttaaataaa tcgttattta tttttactct cacttaaaaa agcactaaaa
    27421 ttataagaga gggaggtaat ggtctgaaca ccaagaattg ttccaacatc gaattgctta
    27481 actaatgagt tcaaagctta attatgtggc tcttatattt accgagcgtg gattgcgatc
    27541 tctttagcga aacaaacatc tttcataaaa aaaacagcca tatccgcttt cttggatatg
    27601 actatttact actactttac tatctttcat tcttcttgtc tcacttatga taaggcgctg
    27661 ggtatcatga gtgaatgata ttgctgaata caaatagtcc gaccacatta agttgatcgg
    27721 acttcataag cattttattg actaatactt ttttgcttaa gaattgattc taacatcttt
    27781 tgctaaagtt aagcatccta tagttcctgc attatctgct aacttaggtg tgacaatgta
    27841 ttcttcgata tttggcgtat cgacatagcc gttaattagt tctaaaaaac gtctttgtac
    27901 tttctttttc agatgttctt gttgcatgac accaccacca aaaattataa tatctggtga
    27961 aagcatcagg gtcgtattac aggcacattg tgcaatataa tccgcctcga tttcccagaa
    28021 cggatcttct atagaaagat cttgtccctt ggttcccgta cgcatctcga tagcgggtcc
    28081 agatgccaac ccttcgagac aatcatgatg aaaaggacaa gtaccagaga aagtatctcc
    28141 tgaatgtctc ttaactaacg tatgccccat ttctggatgg ctaaaccctt caacaaaaat
    28201 cccatcttgt atagctcctc caccaattcc agttccaaca gtgtaataaa caacactgga
    28261 taaacctttt ccatgacctg aaacatactc cccgtaacaa gcagcattca catcggttgt
    28321 ccaggcaatt ggaatttcga aatgcttatt caacgttcca acaaaatcaa aatttttcca
    28381 ggcagttttt ggagtagagg tgatatgtcc ataggtcttt gattcacgat ggatatcaat
    28441 cggtccaaat gaccctactc caatgctttc taattgttct ttatagtgat taaagaaatc
    28501 aattaccaaa ctcattgttt cattcggtgt agttgtagga aaactcactc tttctaaaac
    28561 ctttaaatca tcattgccaa tggcacaaac aaatttagtc ccacctgctt ctattgagcc
    28621 atacatttct tactccaccg tccttttatc taggaattcg ttcttccctg tctaatagtt
    28681 tttcgaaaaa ctcatgtggt tccttttggt accaataggc aacagaagaa atatcgtctt
    28741 gacgctcata aagcttgatg tcatcatttc ctagggtttg gaaagtaaca cgtaaatttt
    28801 ctttgaaact aatggggtcg ggtaaatgcc agcggtacaa cccatgcatc ggtaaagcat
    28861 catcgccaaa accatgaact ggatttggat taggttttcc agcactaaaa taatcccggg
    28921 tgtgatctct tttagattga aaaggatagc ccataaatag cgtattaaaa ttttgagcat
    28981 atgccctttc tccaaagttc tttttatgga aagcccaagc gccgccaaaa taatcttctg
    29041 ctcctgtaga tgttattgta gggaaatctt catctccatc tatataaaac ttaaattctc
    29101 cttcccccca ccagtatctt tccaatgcgc acaaagcaaa gtaggttcct acataatacc
    29161 cagtgccttt gattccatca ataagggtgt aatcttttcc ttttgtcgtg atgggttcac
    29221 ggttccattt agcatgaaaa tacatcgcat catccggtac ttcagtcaat gcataattaa
    29281 atgtataaaa aatgtgctta ataaactcag gatgttcatt cgttaaagta atcttagctt
    29341 tttttcgaaa tggcatctca aaatagcaat tcatccctga tgttggattc actacgattg
    29401 gtaaggaatt cacttcgcat cttgtcccaa acccattaca aaaaaaatct cctaatggac
    29461 tttctacaga aggagtggat tcatcatccc aataaatacg caaaattaaa tcacgtaaga
    29521 cgaaactccc agcgattgtt ttgtctgtca ctgtcatcca aaaatgacgt aaaattccag
    29581 ggccttccat ttctgctaaa gtaattgtct ctccagcatt tatcggaaca gaaggtgacc
    29641 cttttctccc aattcctaga tgactcgctg tcattgccgc tttccctttt tcaccatttt
    29701 tattttctgg tgaaatagtt ctactttcct ctcccttgtg gagccatata ttatttaaac
    29761 aattcatttt attcgtcctc tatcctttct tcactttttt gattattcat atagatgatt
    29821 tgttgttgtg cctccgcaat aattgctcca atatctaaat tatcatttcc taactgcaaa
    29881 gcgattgaca ttgccaaggg aagattcatt cctgcaatta cgtgcactct gtcagaaata
    29941 taggtaaaaa acttttgatt tacacttcct ccagccatgt cagttaaaac aattatttcg
    30001 tctgtagtat ccactaactc tttaatttgt tcatctatat catcaatttc ttcgacatat
    30061 gcacataagc tactaatttg attatgcata cctgttaaaa actctagtgt ctctttaaaa
    30121 ccctcagcta gtattgaatg gctagcaatg atcaatcttc tcataattca aatccttttc
    30181 ctttacgcta atattccaaa tgcagccata accatcgcaa aaacaataac gagtagaatc
    30241 aaaatggtca tactgatttt tttcttactg agtagataat atgctgcagc agtaataatt
    30301 actggaatta atgttggtaa aattttgtcc aacattggtt ggattttcat actaacttca
    30361 ccaaaagtga atttaagtgg cgttgaaaca ctgataactg aagcaattaa tgatccaact
    30421 actgttagcc ccaatactga agcagcttca gttaaataat taatcttttc accgtattca
    30481 gtaacaatct tcattccctg cttataacca aattcaaagc ctctcattcg gaaaaagaag
    30541 attaccatga ttaaaatgaa ccataaaaag attcctacag gattattttc taaagccata
    30601 taagccgcaa ttgatcccat gatggttggg atcatcgtca tcaaaagaga gtccccaata
    30661 ccagcaattg gacccatcgt accaacttta aagtcattaa tcgcatcttt tgcttctaat
    30721 ccttgctttt cctccattgc aacacaagca cctaaaataa tggctgccag ccaaggctgt
    30781 gtattgtaat actgaaagtg attatttaaa gcttcgatgt attcatcatc atctttgtat
    30841 aattttctta aaataggtga caatgcgtaa gtcacagatg caccttgctg tgtttgataa
    30901 ttaaaggtac aaactgacat caaccaacga tagttcgctt tcctaagatc ctttttcgtt
    30961 acttgatatt tttcgctcat tttattcatc ctccccaata aacccaacat cagaagctcc
    31021 cgcagaagca gtgatttgtg catctttttc agctctatga tacacattaa atgctaaagc
    31081 gaatcctatg atcgccgctc caataatagg taccttcaaa aaagcggcta agaaaaatcc
    31141 aacaagtaaa taactaatgt atcgacctgt aggcataaag cgtaacaaca tcgcaatacc
    31201 aacagcaggc aacatttttc cggctaatgt tagcccatcc ataaaccaat taggtaaaac
    31261 atccaaaacg taattaacag cagactgtcc taaagtaacg gcaataaata ctggaattgc
    31321 tgcagataaa ccaaagaaaa ttggccccaa ccacaaaaca ctattcattt tcttaaattc
    31381 tcgtttattc gcatattcct gtgatttgcg aacaacaaaa ccatttaaga ttttgacaat
    31441 tacatctagt tgcaccccta acatacctac aggtagtcct attgctaatc cggcttctac
    31501 tccaagctgg ctaccaaatg ccgttgcaat aattgcgcac gttccatagt ccggtacaga
    31561 tgagccacca aaaccggcaa ctcctaatga catcaattga actgtaccgc caactatcaa
    31621 acctgttttt atatcaccca tcaaaattcc tgtgaataat ccccaaaaaa ctgcgtaatt
    31681 tacaaagatc atcggaatcc cataataatc aacatgttta ataaatgcta atatagtcag
    31741 cataataatt tgaaaaatag taaaatgcat tatccttact cctttatcct aattttgatt
    31801 gaatttcctg tgccttatcc gccggaacaa attgtgtaac aatttctaca ccagaatcca
    31861 acaatttttt atacgtgctg atattttcat ctgatgcata ggctctagaa gatagctgta
    31921 atgcattatc tttaacaaca gtaccgccaa caattagtcg gtcaattcta ataccgttat
    31981 ctactaaatg aaggattgtt tccggctctt tcacgatgac aaatactttt tcctgatcgt
    32041 atttcccctt tttaaaattc gcaatcgctg tttcttcagt gataattgat acagccattc
    32101 cagcaggtct agctaaacgc atacttgatt tttggatgtc gttatttgcg acagaatcat
    32161 cgatcaccat cactctgttt gctttagaca ttggtgccca ttgcgtgaca ataatcccat
    32221 gcaataaacg gttatcaact ctcgacataa caatactcat aaatacttcc tcctttatct
    32281 ttcattttct tacaagcaat taccatgcca aaacaaaaag aacttgataa atcaagctct
    32341 ttttacataa tcataaacgt atttaacctc atgaatcggg atgtcgacac tataataatg
    32401 ttcaacgaca ctgaaagatt gcttaaaatg tgtctgaaat ttttgaaatt cctcactcgt
    32461 ttcattgaaa taaatttcat cttccaaagt attttgtttt actaatcgtt caattaagca
    32521 actaatgtga acatataatc cgaaacacgt attattatca aatgaaattc ctagatcatt
    32581 ttgtaagatg tatatagcat ctgaaacccg ttctaataat ttagtcggat ttaatatggt
    32641 caattgctcc attaaattcg ttagactaaa attcttcaga atattattgt tcaaaacttt
    32701 cagttcatta tcattaaagt gtctattcaa ttgattggag aatttactta tattcattcc
    32761 taaaatcata tcttcaattg aaaagaattc tacatcttct agatgtggat ttagtgttcc
    32821 aacaataaaa agaatattgt tctctttacg aagctccgat aaatagtttt cattcactaa
    32881 agagtaatag tcacacgttt ctatgacaag atcagtatcc cttggaaagc tatcttcaag
    32941 tatctttttt aatttaaacg aagttcctaa tccgcttgca caagaacaga caatcatatc
    33001 cttcttaata tttgatgatt cataaatata atccacattt tgattttctt ttacttgttc
    33061 aagaatctgt ttaagcggta aatctaataa tatctgattt gcaacatcaa tagccattct
    33121 tgttgaaaca ttgtttagta gtccgaattt tttttgagcg tctagttcca aatttagata
    33181 aattttctcc agtgaaccca tatcaacaag taaaataatt tcttcatatc cggtacactc
    33241 ttgtaagtat ctattaattt tgtctgcaat ctcactactt gaagtcatta gtggcatatc
    33301 aatggcgtcg tatatatatc tctcaacgat cctattagca gtacttgcta tacaggttgc
    33361 cgttagatct ccatgagcca aaatcagtgc taaacgtttt tgctgaaatt ctttactaca
    33421 cattaactta aataaaataa ccaaaacatt tttttgaatt tttgttaaat aaatatcccc
    33481 tatttgaata aaacgattga ctaattgaac ttctcgacta caccaactat taatatcatt
    33541 gatgaaggaa tataatttat cgtccgatgt taattggatt tgataaatcc aagaattcaa
    33601 aaagatagac gttatttgaa gataataata gtcaaattct atttgaaaat ctctctctat
    33661 ttccttaaca tactgtctaa atcgaatctc ttgataggtg ggatatgtta aagctgaatt
    33721 attttggata tcaacattct tttgtctaaa atatctatca tatttctcaa aaagctgctg
    33781 cttatcagtg tctttcttcc acgtttgata aagatactct ataagttcgt tgatattaaa
    33841 aacttcgtct actttttcca aatcatccat ttgaatatat tttaattcat tctgtctttt
    33901 cataaccttc atgccgttga aattcaccca ttgtggtaaa tgatacatct gaatataaag
    33961 ttcttccaaa tcatctaaga aataaaaggc attggcacag gtcaattgaa tgatattttt
    34021 caaattgcca acattttcac taaagcgata gtttaataaa aaatctaata attgttgaga
    34081 tatcagtatt ttctttgcta gtctttcttc ttctgattta aaaaatatct tgattaactg
    34141 ttttctttca taaagagaac gactgtctaa tgttggaagt gttagcttta caggtattct
    34201 tctcaacaaa gttgataata gtttatcctc aggtggttct gatgttgcaa atataatcca
    34261 gcaacttgat gtgtaccagt tttcattatc acccatccga tgaaatttcc tcgtatccat
    34321 aaactgaaaa agtttctcct gacattcatt gctcaatgca tgaatttcat ctaaaaataa
    34381 gactccatta ttagctaatt ctgctaaacc ctttcttcca tcttcggctc ctgtatatgc
    34441 accttttaca tgcccaaaaa aattggacaa gaaaagttct ggattattgg catattcact
    34501 acaattaact gaaatgaaag atgccttctc ttctatataa ttattggcca acaaatcctt
    34561 atacacataa tttgctaaat agctttttcc agttccagtc tcgccatgaa gtaaaatggg
    34621 taagccattt ggcggatagt agattgctgc tttaatttga gcaattacat ttcgcagact
    34681 tccttgactt ccgataaccc tttctattcc aaccctaaaa gagctatcat accatttttc
    34741 cgcttcctct gaagagctaa aaatttgttg atttggaact ttctccggta aagaaaagaa
    34801 gattactgga cgagtattga tttttccaaa ttctccatct tttacgaatt cattcaaata
    34861 ttgagagaca atattacgac taacatttaa tttttcagat attttctgtg ctgtattgtt
    34921 cccccattta tttttaatct cagagttctc tatgacataa ttgacaatgc gttcttttaa
    34981 ttcttccatc acagcacctc ctcgacacta ttcgaatttt gccgacagta tttttccata
    35041 aatatgactt gctaaaaagg ctttgtttag atcattcaat tggaacgttg cttgttttgc
    35101 ttgatccgct aagacgttga aaagatactc tggcgaaatc gcatacccca aaatatcaac
    35161 gattgttgca atcagatctt cttttgattc ttcatctgaa agtaattcac gatacaacat
    35221 cgtttgtttg cttactgtgt catattcctc taaggattca tctgctaaaa gaaccacttg
    35281 ttccaacaaa cggtcggata aatatttata gaaaatcagc cccaataaat aatttttata
    35341 ttctgacgca tccattttac tacggagatt atctgccgca ctaaataact tctgatttaa
    35401 ttctgcaccc aaaaagatac actcctatct cttatttaaa gttgctatat accctcttat
    35461 tttagcatac tcagttttag aaaaagcaaa aaaataaaga aacttattct tgataacaag
    35521 ctacgtgacg tatatcccta acacaaaaat agccatatcc tttggtttgg atacggctat
    35581 ttgatattac tcattcaatt atcaaatcac agtaggtgtg aatctcatcg ggatcggcaa
    35641 tatctacttc tgattaggat caaaggtgat tttctcaata aaggtgtgat acaaagcttt
    35701 aacttgcttc ttctcactct ggataagaaa gcaatccaaa ctagtcaata tctgttggac
    35761 atctttgact tgaatcggtt ccccttgttg ttgaaagatc cctaagattt cattctctcg
    35821 aatttgtaac tgtcttcgtt tttcagtcaa ttcatttaaa cgatctttta acatcggaaa
    35881 caattcggga ctatcttcca aagcagcttc ctgtttttgc tctaatagtt agattttgcg
    35941 taccattttc ttcttttatt ttccttcgat tgctgatttt aatatagtct aaaggaaatt
    36001 tatatttatt gtattcttta taacttcaag agaacttcgt ttgagtatta ctgtattttt
    36061 ttaattccat aagaaaatta gttattacct gccacctaat cagcaaatct gaacctgagt
    36121 caatataatt aatattattt tccatctcca acattgtaag tactgttggt gttaatatag
    36181 ggactttgta caattgtatt tttttgattt tatcatctgc acaaaggaga ttttttaaat
    36241 ctaatccttc ttttatttca aaagttgaat tttttaaatc tataagagta aaaccaattc
    36301 cttcatactg aatttctgaa aatcgaattt ttctcccagt tgatagatca aggggcagaa
    36361 aaccttttat tacattgtga gtgtcaccat catttacaat gtcattagga attttgattt
    36421 tagaattctg tggagcacct attggaagat aataattcat tataattttg tagtcttcat
    36481 gaggaaataa agtactttta ggattgctaa gatattctcg taccgaatct aagaatggct
    36541 tatccattga atcttcatcc ccatttaaac taaaaaacat tcctacaatt gcttttgcaa
    36601 ctctaagtga attcattttc tttattgaat gtgttaaatc agacttacca ttctttaaac
    36661 ttgtattgtt ataaaggaaa tttttattgt cttctgcaaa tctaatatat tcctcaacat
    36721 actcactacc aaaaaaacta ttacatttac tacataacgt attggaatgg caacagtttt
    36781 tttgacaaat tttataaggt gcagaacttc tttccgtatg ctattccgat tgtccttgac
    36841 aatgagcctc ctcggatgtg acgatcttcg gcaggagcta acagttaaag ttagactgcc
    36901 tcgctagcgt tagcacatcc gagctcatta tcaaggattc gctgcgccaa t
//
LOCUS       DAZULR010000028        34875 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.028, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000028 DAZULR010000000
VERSION     DAZULR010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34875)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34875)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34875
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.028"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            537..1265
                     /locus_tag="ACG8ZV_001582"
     CDS             537..1265
                     /locus_tag="ACG8ZV_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFS4996925.1"
                     /translation="MESSSKGKSLYYQLVDVLKERIETQMTPHDKLLSERELCQHYGV
                     SRTTVRLALQELETQGYIYRRHGKGTYVSDLSDKSSDLAGAYSFTEEMRELGRVPNTV
                     ILEFKQMEANKKVAKNLNINLGETVFKLKRLRLADDEPLMVERSYLPAKLFIGLDLPL
                     LESKPLYDVFSQDYEQQVQLADEEFYASIVQKKDADPLRIADGAPVLYLSRTTYNVKN
                     EIIEYTDSVARADQFHYKIRHVRK"
     gene            1283..2476
                     /locus_tag="ACG8ZV_001583"
     CDS             1283..2476
                     /locus_tag="ACG8ZV_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFS4996926.1"
                     /translation="MFELSKDKLKELGAEITTREIKQQPQLWKETAEILAQNQEKLAL
                     FFDQIKKAANGKRVRVIFTGAGTSQYVGDTAVPYLNEYGDNDHFIFHSFGTTDIVSSP
                     KEFLFPDEPTLLVSFARSGNSPESVATVKIANEQIKTLFHLTITCAKEGQLAKNAATD
                     ERNYLLLMPEKSNDAGFAMTGSFTCMLLSALWVFDQTAVEKKESYLQQLIRTGEDLIS
                     RDQEIQKLLPKSFERIAYLGSGSLAGATREAQLKILELTAGKVATIFDSSMGFRHGPK
                     SFLNSETLVIGFVNNQPYTRNYDLDILEEIKDDQITTSVIAIAQPGNIDFTGTSLLLE
                     ASISLPDAYLALPMIMTAQIIALDTSIKVANKPDTPSPTGTVNRVVKGVIIHEYVNKG
                     ETKDE"
     gene            2469..3464
                     /gene="lacD"
                     /locus_tag="ACG8ZV_001584"
     CDS             2469..3464
                     /gene="lacD"
                     /locus_tag="ACG8ZV_001584"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HFS4996927.1"
                     /translation="MNEEKIAAMKSLSTKEGIISALAIDQRGALKKMIKALGKEPTAQ
                     QITEFKELVSAELTPYASAILLDPEYGLPAAKARHQEAGLLLAYEKTGYDATTPGRLP
                     DLLADWSTLRLKEQTADAIKFLLYYDVDEDPEINHLKHVFIERLGSECAGEKRPFYLE
                     LVSYDAKTNDSTSLEYAKIKPHKVIEMMKEFSDPKYKVDVLKVEVPVNMNYVEGYSDG
                     EIAYSKKEAAAFFKEQSDATPLPFIFLSAGVSTALFQQTLIFAHESGSTFNGVLCGRA
                     TWKDGVKAYVENGREGAIEWLRTQGRQNIESLNKVINENATPWFDKVKEDSVTAK"
     gene            3461..4402
                     /locus_tag="ACG8ZV_001585"
     CDS             3461..4402
                     /locus_tag="ACG8ZV_001585"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hexose kinase"
                     /protein_id="HFS4996928.1"
                     /translation="MITTVTMNPSIDIAYTLDELRIDQVNRVKTVNKTAGGKGLNVAR
                     VLHLLADDVLATGLVGGQHGAYIKEQLDQSGITHQFLPIKGETRDSIAILHGVNQTEL
                     LESGPVVTEEEQHKFTEHFARLMETTDIFTISGSLPQGFSKSYYAELLALTNKKGTRV
                     LLDTSGQTLLEVLEGKEKPFLIKPNLEELGELVHQTISSATSLDEIQSLLDHPLFEGI
                     NWIVLSLGAKGAIAKVGRHFYQVTIPKIAVVNPVGSGDSTIAGLAHALSKSYTIEETL
                     AFAMACGMANAQQEKTGWIDPVKVDYFRGEINVRKIR"
     gene            4448..6214
                     /locus_tag="ACG8ZV_001586"
     CDS             4448..6214
                     /locus_tag="ACG8ZV_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0004565 - beta-galactosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase family protein"
                     /protein_id="HFS4996929.1"
                     /translation="MTRFEIKEEFLLDGQPFKILSGAIHYFRVHPTNWERSLHNLKAL
                     GFNTVETYVPWNLHEKEEGTYDFSKILDLSHFLELAQSLGLYAIVRPAPYICAEWEFG
                     GLPAWLLTKECRIRSADPRFMKYVKRYYQTLLPKIVPHLVTHGGNVLMVQVENEYGSY
                     GEEKAYLRQVKKYLEEGGIDVPLFTSDGPWQATLRAGILIDDDVFTTGNFGSKAKENF
                     ADMAQFFEAHGKKWPLMCMEFWDGWFNRWKEPIIKRDPEELADAVKEALQIGSINLYM
                     FHGGTNFGFMNGCSARGAIDLPQVTSYDYDAPLDEQGNPTEKYFALKRMMAENFPEMQ
                     QMEPWIKETIVKKGINLKEKVSFFATLDTISKPIHSTYPQTMEELGQNTGYLLYRTTI
                     KKDAVNEKLRIIDGRDRVHVFLDEEKQAIQYQTEIGETIPLTLEKEDHQIDLLFENMG
                     RVNYGHKLLADTQRKGIRTGVMSDLHFITEWTQYCLPLETTEHIDFSKKWEAGQPAFY
                     RFEAELSEIGDTYLDLSEFGKGIVWVNGTNIGRFWEVGPILSLFVPEGLFRKGQNEIV
                     IFETEGRFSEVIDFVKEPIEKS"
     gene            6231..6710
                     /locus_tag="ACG8ZV_001587"
     CDS             6231..6710
                     /locus_tag="ACG8ZV_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HFS4996930.1"
                     /translation="MAIIGVRIDGRLIHGQVANLWTTKLNIGRIMVVDDEVATNAIEK
                     SGLKLATPAGVKLSILPIEKAAANILAGKYDSQRVLIVAKKPDRILALVEKGVPIKEL
                     NVGNMSQTDETRSITKSINVVDADVEVFKKLDQLGVHLIAQMVPNDKAEDFMSLLIK"
     gene            6723..7613
                     /locus_tag="ACG8ZV_001588"
     CDS             6723..7613
                     /locus_tag="ACG8ZV_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFS4996931.1"
                     /translation="MDIQWWQILLLTLYAGYQILDELQIYSSMSAPVFAGLYAGLVMG
                     DLKAGLIIGGSMQLTVLGVGTFGGASKIDANSGTILATAFSISLGMNPEQAIAAIAVP
                     VASLMIQLDILARFANTYFAHRIDQHVETMNYKAIERNFLMGALPWALSRMVPVFLAL
                     AFGGGLVQNVVAVLNGDLKWLGDGLSVAGAVLPAVGFAILLRYLPVKKHISYLILGFT
                     ITALLATVFSNVQLLGTSVASVVKDFPGTFNSLPMLAVALIGLALATISYKNDQKNDQ
                     HPVVSQQSQSDEGEIEDDEI"
     gene            7600..8409
                     /locus_tag="ACG8ZV_001589"
     CDS             7600..8409
                     /locus_tag="ACG8ZV_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFS4996932.1"
                     /translation="MTKSNYKLTKEDFKQINRRSLFTFQLGWNYERMQGSGYLYTILP
                     QLRKIYGDDTPELKEMMKTHTQFFNTSNFFNTIITGIDLAIEEKEGVSSKETVSGMKA
                     GLMGSFAAIGDSVFAALIPTIFGALAANMATDGNPVGILIWILAQVAVMVFRWKQLEF
                     AYKEGISLVTTMQSRLTALTDAATLLGVFMVGALVATMINVKFSWAPTIGDVTLNMQN
                     YIDMILPKLLPAGIVGGVYWMLGKKNMTPTRAIFIVLIVCVALSALGVISK"
     gene            8425..8829
                     /locus_tag="ACG8ZV_001590"
     CDS             8425..8829
                     /locus_tag="ACG8ZV_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFS4996933.1"
                     /translation="MSRQLVLISHGKFCEELKNSTEMIMGPQENIYTIPLLPEDGADT
                     YKERFLSVTAPLKDYVVLCDLLGGTPANTVSKLIMEGETIELYAGMNLPMVIEFINSQ
                     MIGAEPDFIGSGRESIVSVNQVIAGMGDDEEE"
     gene            complement(9010..9948)
                     /gene="yidC"
                     /locus_tag="ACG8ZV_001591"
     CDS             complement(9010..9948)
                     /gene="yidC"
                     /locus_tag="ACG8ZV_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0051205 - protein insertion into membrane
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HFS4996934.1"
                     /translation="MNKWKNWLLGSGLVTIMLFLSGCVRMDSNGNPDTSGIIYRILVH
                     PMGQAITYLVENFNWSYGWAVILMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     ATQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESTFYGIDLGNPSLVLVAIAGIAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGIFSCLQTFITNVIMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTPAEPAKQTKKQVQAPKNNAKNGRNAGKQQKRK"
     gene            complement(10282..11364)
                     /locus_tag="ACG8ZV_001592"
     CDS             complement(10282..11364)
                     /locus_tag="ACG8ZV_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HFS4996935.1"
                     /translation="MTKNLIVRGAPQEYEIKENAWDSLPEHLYKRHIDNVLILHGKTS
                     WKAVKDVFPDLSITKIFEYYGGECTDPLADSFVSLCKKKDFNGIIAVGGGKVADLGKL
                     IAYKTNLPIIILPTLAATCAAYTPLSVVYNEEGVMLRYDMFPKANDLVLIDPKIILHS
                     PREMMIAGIGDTLAKWYESHAIISQLTIKPIEVQVAEFAALRCREILLEKSAEAMEAM
                     DQQKINQAFIDVVETNILLAGMVGGFGDDYGRTAGAHSIHDAMTVLPDSHQQLHGNKV
                     AYGILVQLMIENKLAEIEHLLPFYHHLNLPTSLADMGLHLTESDYQAVAERACLPDEM
                     IHFMKETITPALVVQKMKELEQVTQG"
     gene            11506..12957
                     /locus_tag="ACG8ZV_001593"
     CDS             11506..12957
                     /locus_tag="ACG8ZV_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HFS4996936.1"
                     /translation="MKKGINILLVALMFLLVFLPVKVQGAEKDEIYERIKQSGELVVG
                     LSADYAPYEFHANVDGKDKIVGFDVSIAEKIAKDMGVKLKVEELGFDALLGALKTGKI
                     DLVISGMAVTEERLQEVDFSDPYFVVQQKVLVRKEDKNKFKTTADFSGLAVGAQKQTT
                     QEELVKNELTGAELTSLQKVPDLINNLLNEKVEGVVLEQPVAEAYAQQNKKVALTPVK
                     FAQGEKTTAIAMSKNTPELKNHVNASIKTINDDGLLKDYQKQANQLMFQDDQSFLQKY
                     GPYYLIGTKYTILLAFVGVLFGMVFGSLLALMKLGKNKFLKALAIIYIEYVRGTPLLV
                     QIFIVYFGTGVLGLDLSKLVAGCIAVSLNSAAYVAEIVRAGINAVNKGQMEAARSLGM
                     DQKEAMRFIIFPQAIKNILPALGNEFVTIIKESSVVSVIGVSELIFQTGVVQGASFKP
                     FLPYVLVSLIYFVLTFSISRILALVERRMGLNA"
     gene            12950..13672
                     /locus_tag="ACG8ZV_001594"
     CDS             12950..13672
                     /locus_tag="ACG8ZV_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFS4996937.1"
                     /translation="MLNVKKLSKSFGENEVLKSIDLSVKEGEVVVIIGPSGSGKSTIL
                     RCMNLLEEPTSGEIFFKGQNITAPDSDINQIRQKMGMVFQSFNLFPHMNVLENLTITP
                     VKIKKEDPKKAKEHALSLLNQVGLKEKVDSYPTSLSGGQQQRVAIARALAMNPDVMLF
                     DEPTSALDPEMVGEVLAVMQDLAKKGMTMVVVTHEMGFAKEVADRVIFMADGIIQEEG
                     TPKEIFENPQNSRTQDFLNKVL"
     gene            13692..14843
                     /locus_tag="ACG8ZV_001595"
     CDS             13692..14843
                     /locus_tag="ACG8ZV_001595"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFS4996938.1"
                     /translation="MDKSKIARRFQQPAENLLMNIAILAKEKEDIIDLSIGDPDLITD
                     PTIIEAAYTDVKNGATNYTAPDGSKEFLSTVVDFYQKKYGLSVECNQVRATVGAMHGM
                     YLVLQALLDPEDEVIIHEPYFSPYREQVILSGGKPVFVPTYEEKGFQLDVEDLKAAIT
                     DRTKVIVINSPNNPTGAVFSESTLKKIAEVAIENELYIISDEIYEDFAFKEKFVPMAR
                     FAPDNTITVSGVSKGFAMTGWRLGYMIAPAYINQIAGLINENITYSAPTASQRGAIYA
                     LKHYEQLVPPVVEVFKERLAYIEKRVAEIPYLSLSSVSGSMYAFINISKSGLDSVTFV
                     EEVLEKSGVLFVPGKAFGETIGDNYIRLAATQPLEILGEAFDRLAKLNF"
     gene            complement(15191..15466)
                     /locus_tag="ACG8ZV_001596"
     CDS             complement(15191..15466)
                     /locus_tag="ACG8ZV_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HFS4996939.1"
                     /translation="MNKIKMNVQGRVQSVGFRYMTKIVADQLGITGTVKNEDDGSVTI
                     EAAGDDEAIKKFVEEVKRSPSPSGRVQYVDLQENPMMEDRKKFVVIG"
     gene            15574..16338
                     /locus_tag="ACG8ZV_001597"
     CDS             15574..16338
                     /locus_tag="ACG8ZV_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HFS4996940.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKGEYLLEGFHLIEEAVAS
                     NAKVNELFITQRGLTEWASWLEENQALSVTLVSEEVMATVSDLPTPQGIMAVVEAEKR
                     EIPNFEGGWLLLDNVQDPGNVGTMIRTADAFGLSCVVLGKGTADVYSTKVLRSMQGSN
                     YHLPIIQEDLTKLLPILKEQGFITYGTELNEEAVSLNDIQTTENYAIVMGNEGQGVRP
                     EVLALTDKNVYIPIQGNAESLNVGVAAGIMLYHFSV"
     gene            16462..16965
                     /locus_tag="ACG8ZV_001598"
     CDS             16462..16965
                     /locus_tag="ACG8ZV_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFS4996941.1"
                     /translation="MTEKWREDEEYMSYINDLLETDAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYKLAKKWGGDARATARAGLLHDLFYYDWRTTKFDEGTHAYVHPRIAVKNAEKI
                     TELSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMTASMKQKWQRY
                     FGKEQSI"
     gene            17230..17877
                     /locus_tag="ACG8ZV_001599"
     CDS             17230..17877
                     /locus_tag="ACG8ZV_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HFS4996942.1"
                     /translation="MEKTIKPYQYYFIKREVEQLLSAYSSVNDPKTVQTVQALAAEKI
                     HEVLGHPNTAVNEFMEKVLDVTLKKEKAERLLEELKVIVLPFIQPTKPQIDKLFRKVK
                     KLKQPDWNQLDLREHTYIGWNDPGSQKKFMIYYEEEKLKGISGTLSPTINKGICSICQ
                     RTSNVSLFLSTTKTGSDGTYTKKGNYICHDSDQCNQQLVQLAPFYEFTERVKRER"
     regulatory      17920..17987
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01734"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Fluoride riboswitches increase expression of
                     downstream genes that help mitigate the toxic effects of
                     very high levels of fluoride; They are found in a wide
                     variety of bacteria and archaea; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="fluoride"
                     /db_xref="RFAM:RF01734"
     gene            18038..19306
                     /locus_tag="ACG8ZV_001600"
     CDS             18038..19306
                     /locus_tag="ACG8ZV_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HFS4996943.1"
                     /translation="MENRLPDPLKVIIYMIKWLLITAILGIFMGSLSAFFLTSLTDVT
                     AIRLEHPWLLFLLPISGGLFAYLYTTYGGNSSRGNNLVIDQGNGGNEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALAENFARWLKLNKIEREILVISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEALFPSFFAALFANFVTESFNVKHTHYQMGAIPAWDPS
                     LFFKLLLAGIAFGIIGWLFSRSIVWLKAWYAKRIPHPVLRNFIGGAVVVLVVVILQTQ
                     RYLGLSLPLLQDAFNGSAHPYDFLGKLGFTVLSLGAGYQGGEVTPLFEIGATLGATLA
                     PILHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGGQAASYFFMICLISFMCSGN
                     SGIYSAQKVEVKKGILFLPILGRISRQKEK"
     gene            complement(19483..20685)
                     /locus_tag="ACG8ZV_001601"
     CDS             complement(19483..20685)
                     /locus_tag="ACG8ZV_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HFS4996944.1"
                     /translation="MNLTRDLIFLVIYILGMSGILYWRKRQSDPALFFYCGTWTFMMM
                     VTYFVVLEVFYHTFYFLIPLLFFSIFAFFYFKEKRRLINGVLFNTFLIVFGGYLGWLL
                     IETQNIFIGGLLALIGIPILILLAIGIYILIIFLFWNGVVVMKKESRSLANLLTLLLG
                     VALTIFLILDYTLVHWLPQWANALFAVIPFIFAYLLIVFFNFMTVSILYQFNRPRYNQ
                     DYIVVLGAGLIDGERVSPLLAKRINKAIAFYWAQSKATLNPPVLLMSGGKGTDEKVAE
                     AIAMKQYALEKGIPERDILVETNSTTTLENMLFSKEIMDQQMNGPYRAIFTSNNYHIF
                     RAGLYARQAKLNANGIGAKTALYYLPNAILREFIAILVLHKKRHLIICGLMIGFAVFS
                     ALILKFAQ"
     gene            21212..21937
                     /locus_tag="ACG8ZV_001602"
     CDS             21212..21937
                     /locus_tag="ACG8ZV_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTC domain-containing protein"
                     /protein_id="HFS4996945.1"
                     /translation="MNKKRFKRIERKFALTYDQAKYLKTLFPKQVVRDKYSDHFISSL
                     YFDTNDHHFLKEITTEKSYREKFRIRKYGDPQDISPIYLEIKRKFQGMTDKRRIKLAH
                     HELDDMLENIELAETTFSNLEEEYIFNEIQWLFRRLALEPKVYIYYLREAFVNRDSED
                     LRITFDQNIHYRLMNLTTWEHCTEDNLVAPEIDVLMEVKTTGEIPEWLQVGLDRMGKK
                     EIKFSKYKQVYKRYIQEDPLYVQ"
     gene            21927..22601
                     /locus_tag="ACG8ZV_001603"
     CDS             21927..22601
                     /locus_tag="ACG8ZV_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HFS4996946.1"
                     /translation="MFNSVLKNEPSQLTLDDFFLCMVVSILLGILIAYTHMYQNNCTK
                     NFMFALIGLPTLVHTVILLINGNLGTGIAVLGAFNLVRFRSAQGNSRDIFSIFWATSI
                     GLATGTGYIVYALFVSSIVAAIQVIIFTLPIKNKHTVFNTEKTIKLKVSKSLFLSSII
                     EEKIAEYTENCNLKKVKINKETCSLHYIVKVKTSMLEKELVRTIMDHPEVISITVGMD
                     KSNKLL"
     gene            complement(22889..23173)
                     /locus_tag="ACG8ZV_001604"
     CDS             complement(22889..23173)
                     /locus_tag="ACG8ZV_001604"
                     /inference="COORDINATES: protein motif:HMM:NF024076.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 family protein"
                     /protein_id="HFS4996947.1"
                     /translation="MRQKCFLLLSHSQKVKPIFWLSIWDGFFKVSFHFPEKTREKLVT
                     LSLSEGTKEKIKTLQANGNKRKHLSVIFDVDHLEQLADIYQLAEFKKQNG"
     gene            complement(23467..24774)
                     /locus_tag="ACG8ZV_001605"
     CDS             complement(23467..24774)
                     /locus_tag="ACG8ZV_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008800 - beta-lactamase activity
                     [Evidence IEA];
                     GO_process: GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HFS4996948.1"
                     /translation="MFKKNTRFIVLLASLILCITSFLPSATVQADDAFKINAKAAFAV
                     DAESGKILYDQDGEKTMGIASITKIIGLYIVLEQIKEGKLSWEDKVAISDYAEKLSVV
                     PDLSNVPLHKENDYTVKELVDSAFIQSANASMVALAEKVAGSESKFLELMKKQLKDWG
                     IKDATIVNASGLNNSYLGENRPENTGETDENQLSAKDVAIVARHLILDYPEVLKITST
                     TNQTFGENTQSPVEMVNWNWMLPGFVNYHEGVDGLKTGTTDFAGACFVGTINKDGRRI
                     ITVVLNADNHEENPSARFNETSRLMDYCYDNWSEKELGKANASIPSLKDIKVKDGKET
                     SVNVALKSPVKVWVENGMDTGKLTITPTIDKKKVTDDQVTAPINKGTTVGSATIQLAD
                     DKLGYLEANQEPSTDIITTSTVEKANIFVIGWRHVTDFFSNLF"
     gene            25263..26369
                     /locus_tag="ACG8ZV_001606"
     CDS             25263..26369
                     /locus_tag="ACG8ZV_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996949.1"
                     /translation="MAKKEKELLSQLTSEGTKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKITSLLDDPSFWRSATTSVAVIVSPEQVFIHRLGI
                     PVDDQYYVSDLPYLLAIIKNGHFNYSYYLLGLNRDSMKLYEVTNKQVKEVALPEDAPR
                     DVVTALGSELTGGGLNYASNGSEGTTFHGVNPKDEEVEIDWVNYYQAVDDYLKDTFEN
                     PEKWPIFLFALPENQTMFKKVAKNPYYRSDVAISASPAQLSLKEIEAGAKKLSQELAV
                     KEASDYNKLLDKKFIDQLVDIIPAAKEGKISHLFIATSNLADGFGEDPETEYDRRQVL
                     NELADNVITNGGQVFILEQKDAPDEKSLVAILRY"
     gene            26960..27160
                     /locus_tag="ACG8ZV_001607"
     CDS             26960..27160
                     /locus_tag="ACG8ZV_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFS4996950.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            27307..30096
                     /locus_tag="ACG8ZV_001608"
     CDS             27307..30096
                     /locus_tag="ACG8ZV_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase C-terminal domain-containing protein"
                     /protein_id="HFS4996951.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIEAGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSSHTGMDTSRFIYHVLEEMKENPEPLDLSLEIIDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIMEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPGQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHAFFADVAHRGTGFLARNQSFYKQDFVRFLQKKIKQSNFLIVNHAFLVQETQRKEP
                     LLPASPYLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICVAEGLMNLVSSKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAMDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLLDFQAAMLPSTVWYPRYDHILYIGGTLKIGP
                     NRQYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLEAALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAIDEI
                     YQDIHEFLKKNEEGS"
     gene            30143..30670
                     /locus_tag="ACG8ZV_001609"
     CDS             30143..30670
                     /locus_tag="ACG8ZV_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HFS4996952.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            30691..31881
                     /locus_tag="ACG8ZV_001610"
     CDS             30691..31881
                     /locus_tag="ACG8ZV_001610"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFS4996953.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNSEIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            31921..33219
                     /gene="asnS"
                     /locus_tag="ACG8ZV_001611"
     CDS             31921..33219
                     /gene="asnS"
                     /locus_tag="ACG8ZV_001611"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HFS4996954.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVPEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(33540..34841)
                     /locus_tag="ACG8ZV_001612"
     CDS             complement(33540..34841)
                     /locus_tag="ACG8ZV_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFS4996955.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT        11260 a         6136 c         7331 g        10148 t
ORIGIN      
        1 aaacatcgaa aagtatagag cccgaatttt acgaatattt tttgtaatat aaaagtatag
       61 atactaaatt cttattcgtt aaacttacgc cataaggaaa ctagaaaaag acagaattat
      121 cataaaaaat ttttgttatt tttaaaaatg tacaacaaaa tttcgactat cagaccggca
      181 tgagagaaaa gttatctaaa aaataaaaaa tcctacttta tttagagaaa gccattttta
      241 tttacatagt agtctattag gcccatttgc ttgtcgatag tagaaatagc cacagatgta
      301 taaagaatat tttttcttta cttctctaga ccatttagct gaatctttgc caagattcag
      361 cttttttttg ttttttattt gtcaactggt atttttgagg tatcttttga taccagttct
      421 aaattacctt gaaaccttgt tataatagct tttttacgcc aaaaaccctt tgacaaatga
      481 ggaatatgtg ggtattcttg tgttgtggtt ataaccagta aagaagaggt atttttatgg
      541 agagctcaag taaaggaaaa tcattatatt atcaactagt tgacgtattg aaagaacgta
      601 tcgaaacaca gatgacacct catgacaaat tgttatctga aagagaactt tgtcagcatt
      661 atggagtgag tcggacaacg gttcgccttg ctttgcaaga attagagacg caagggtata
      721 tttatcgccg acacggaaaa ggaacatatg tgtctgatct atcagataag tcgtctgatc
      781 tggcgggagc gtatagtttt acagaagaga tgagggaatt gggacgggtg cctaatacag
      841 tcatcttgga attcaagcaa atggaagcaa acaaaaaggt tgccaagaat ctaaacatca
      901 atttaggcga aacagttttc aaattgaaaa gacttcgttt agcggatgac gaaccattga
      961 tggtggaacg ttcttattta cctgcaaaac tatttattgg tcttgatctg ccattacttg
     1021 aaagtaagcc attgtatgat gtgttttctc aggattatga acagcaagtc caattagcag
     1081 atgaagaatt ttatgcaagt atcgttcaaa agaaagatgc tgatccgctt cgtatcgctg
     1141 atggtgcccc ggtattatat ctaagccgaa cgacctataa tgtgaaaaat gaaattattg
     1201 aatatacgga tagtgtagcg agagcagacc agtttcatta taagatccgc cacgtccgaa
     1261 aatgattgag agggaaaaca acatgtttga actatcgaag gataaattaa aagagttggg
     1321 tgcggaaata actacgcgag aaatcaaaca gcaaccgcaa ttatggaaag aaacagctga
     1381 gatattagca cagaatcaag aaaaattagc attgtttttt gaccagataa aaaaagcagc
     1441 aaatggcaaa agagttcgag tgatttttac tggtgcaggc acatcacaat atgtcgggga
     1501 tacagcagta ccttatttaa atgaatacgg tgataacgat cactttattt ttcatagctt
     1561 tggtacgaca gatatcgtgt cttcaccaaa agaatttcta tttccggatg aaccgacatt
     1621 actggtgtca tttgcacgta gtggaaatag tccagaaagt gtggcaacag tcaagattgc
     1681 caatgaacaa atcaagacat tgtttcattt gacgattact tgtgctaaag aaggtcagtt
     1741 agcaaagaat gcagcgacag atgaacgaaa ttatctttta ctgatgccag aaaaatcaaa
     1801 tgatgcagga tttgccatga caggaagttt tacgtgcatg ttgttgagtg cgttatgggt
     1861 attcgaccaa actgccgttg agaaaaaaga aagttatctt caacaattga tcagaactgg
     1921 agaagatcta atttcacgag atcaagaaat ccaaaaatta ttgcctaagt catttgaacg
     1981 tatcgcctat cttggttcag gaagtttggc tggtgcaacg agagaagcac aattgaaaat
     2041 attggaattg acagccggta aagtggcaac gatctttgat tcttctatgg gcttccgcca
     2101 tggaccaaaa tcgtttttaa atagcgaaac acttgttatt ggttttgtta ataaccaacc
     2161 gtatacaaga aattatgact tagatattct agaagaaata aaagatgacc aaattaccac
     2221 gagtgtcatc gcgatcgccc aaccaggaaa catcgatttc acaggtacaa gtcttttgtt
     2281 agaagcttcg atcagcctac ctgatgcgta tcttgcctta cctatgatca tgacagccca
     2341 aatcattgcg ctcgatacgt cgataaaagt agcgaataaa ccagatacac catcgcctac
     2401 aggtacagtc aatcgagtgg tcaaaggtgt cattatccat gaatatgtga acaaagggga
     2461 aacgaaggat gaatgaagaa aaaattgcag ctatgaagag tttatcaaca aaagaaggaa
     2521 tcatcagtgc attggcaatt gatcaacgcg gtgctttgaa aaagatgatc aaagcgttag
     2581 gaaaagaacc aacggcgcaa cagatcactg aattcaaaga attagtatca gcagaattaa
     2641 cgccttatgc ttctgctatt ttactagatc cagagtatgg attgccagct gctaaagcca
     2701 gacatcagga agcaggacta cttttagcct atgaaaaaac gggttatgat gcgacaactc
     2761 caggacgtct gcctgattta ttagcggatt ggtctacgct tagattaaag gaacaaacag
     2821 ccgatgcgat caagtttttg ctttattatg atgtagatga agacccagag atcaatcatt
     2881 tgaaacatgt atttatcgaa cgtttaggca gtgaatgtgc aggtgaaaag cgtccgtttt
     2941 atctagaatt ggtttcgtat gatgccaaaa ccaatgacag cacttcatta gaatatgcga
     3001 agatcaaacc gcataaagtg atcgagatga tgaaagaatt ttctgatcct aaatataaag
     3061 tggatgtatt gaaagtagaa gtgccagtca atatgaacta tgtagaaggt tattctgatg
     3121 gtgaaattgc gtatagtaaa aaagaagcag cggcattctt caaggaacaa agtgatgcaa
     3181 caccgttacc atttatcttc ttgagtgcag gggtttcgac tgcattgttc caacaaacat
     3241 tgatctttgc tcatgaatct ggttcaacat tcaacggtgt gttatgcgga cgtgcgactt
     3301 ggaaagatgg agtcaaagca tatgttgaaa atggtagaga aggtgcgatt gagtggttga
     3361 gaacacaagg gcgacaaaat atcgaatcgt tgaataaagt gataaatgaa aacgccaccc
     3421 cttggtttga caaagtaaaa gaagattcgg tgacagcaaa atgatcacga cagttaccat
     3481 gaatccttca attgacatcg cttacacgtt ggatgaatta cggatcgacc aagtcaatcg
     3541 ggtcaaaacg gtcaacaaaa cggctggagg aaaaggcttg aatgttgctc gtgtccttca
     3601 tttattagca gatgatgttt tagctactgg attagtcggc gggcagcatg gagcatatat
     3661 caaagaacaa ctcgatcaat cagggataac gcatcaattt ttacctatca aaggggaaac
     3721 gagagattcg attgctattt tacatggagt gaatcaaaca gaactattgg aaagcggtcc
     3781 tgttgtgacg gaagaagagc aacataaatt taccgagcat tttgcacgac taatggaaac
     3841 aactgatatc tttacgattt cgggtagtct gcctcaagga ttttctaaaa gttattatgc
     3901 agagttactt gccctaacga ataaaaaagg aacacgagta ttgttagata cttctggtca
     3961 aaccttgctt gaagtcttgg aaggcaagga aaaaccattt ttgatcaaac ctaatttgga
     4021 agaattagga gagttggtcc accaaacaat ttcttcggct acttcgttag atgaaatcca
     4081 atcattattg gatcatccgc tttttgaagg aatcaattgg atcgttcttt cgctaggcgc
     4141 aaaaggagca atcgctaaag tagggagaca cttctatcag gttacgattc ctaaaatcgc
     4201 ggtggtgaat cctgtggggt caggagattc gactattgca ggcttagcac atgctctatc
     4261 aaagagctat acgattgaag aaacacttgc gtttgcgatg gcctgtggga tggcgaatgc
     4321 acaacaagaa aaaacaggat ggatcgatcc tgtgaaagtc gattatttta ggggggaaat
     4381 caacgtcaga aagattcgtt gattataaaa ttagaaagcg gtttctaaaa acgaggagga
     4441 aatttgcttg actagatttg aaataaaaga agagtttttg ttagacggtc aacctttcaa
     4501 aattttatct ggtgccatcc attatttccg agtgcatccg acgaattggg agcggtcatt
     4561 gcacaatttg aaagcgcttg gatttaatac tgtggaaacc tatgtgcctt ggaatctcca
     4621 tgaaaaagaa gaaggaacct atgatttttc gaaaatattg gatctttccc attttctaga
     4681 gttagcgcaa tcccttggat tatacgcaat cgtacgtcca gccccttata tttgtgcaga
     4741 atgggaattt ggtggcttgc ctgcttggct attgacaaag gagtgccgta ttcgttcagc
     4801 ggatcctcgc ttcatgaagt atgtcaaacg gtattaccaa acgctactac ctaaaatcgt
     4861 tcctcatcta gtcactcatg gtggcaacgt cttaatggtg caggtagaaa atgagtacgg
     4921 ttcgtatggt gaagagaaag catacctgcg ccaagtaaaa aaatacttgg aggaaggtgg
     4981 aatcgatgta ccgctattca cttctgatgg accttggcaa gccacattaa gagcaggcat
     5041 tttgattgac gatgatgttt ttacgacagg gaattttggc tcaaaagcaa aagaaaattt
     5101 tgcagatatg gcccagtttt ttgaagcaca tggtaaaaaa tggccgttga tgtgtatgga
     5161 attttgggat ggctggttta atcgttggaa agagccgatc attaaaagag atccggaaga
     5221 attagcggat gcagtcaaag aagcattaca gatcggcagt atcaatctct atatgttcca
     5281 tggcggaacc aattttgggt ttatgaatgg ctgttcagcc agaggcgcga ttgatttgcc
     5341 gcaagtcact tcctatgatt acgatgcacc attggatgag cagggaaatc caacggaaaa
     5401 atattttgct ctgaaacgaa tgatggcaga aaattttcca gaaatgcagc aaatggaacc
     5461 atggataaaa gaaacaatcg tcaaaaaagg aatcaacttg aaagaaaaag tcagcttttt
     5521 cgcaacactg gataccatca gcaagccgat ccactcgacc tatcctcaaa caatggaaga
     5581 attgggtcag aatactgggt acctattgta tcgaacaacg atcaaaaaag atgcggtcaa
     5641 tgaaaaatta cggatcatcg acggacgtga tcgggtccat gtttttctcg atgaagaaaa
     5701 gcaagcgatt caataccaaa cagagatcgg tgagaccatt ccattgacac ttgagaaaga
     5761 agaccatcaa attgatctat tatttgaaaa tatgggacgg gtcaactatg gacacaagct
     5821 gctagctgat acgcaaagaa aaggaatacg tacaggagtg atgagcgatc ttcattttat
     5881 cacagaatgg acacagtatt gtttaccttt agagactaca gaacacatcg atttttcaaa
     5941 aaaatgggaa gcaggtcaac cagcatttta ccgctttgaa gcggaactgt cagaaatcgg
     6001 tgatacttat ttggacctta gtgagtttgg gaaagggatc gtttgggtga atggcacgaa
     6061 tattggtcgt ttttgggaag taggaccaat tctttcactg tttgttcccg agggtttatt
     6121 tagaaaagga caaaatgaaa tcgttatctt tgaaacagaa ggtagattca gtgaagttat
     6181 agattttgtc aaagaaccaa tagaaaaaag ttagaaaagg agaatggatg atggcaatta
     6241 ttggagtaag aattgatgga cgtttgatac atggacaagt ggcaaatctt tggacgacaa
     6301 agttgaatat tggtcggatc atggtcgtag acgatgaggt agcaacaaat gcgatcgaaa
     6361 aaagtgggtt aaagttggca acgccagctg gagtcaaatt aagtatttta cctattgaaa
     6421 aagcagccgc aaatatttta gcaggtaaat atgattctca acgagtgctg atcgtagcga
     6481 aaaaaccaga tcgtatctta gcgctagtag aaaaaggtgt accgatcaaa gaattaaatg
     6541 tcggcaatat gtcacaaaca gatgaaacac gttccatcac aaaatcaatc aatgtcgtag
     6601 atgcggatgt agaggtcttc aagaaattag atcagcttgg cgttcatttg atcgctcaaa
     6661 tggtgccaaa tgacaaagca gaagacttta tgagtctttt aatcaaatag gaggaatgat
     6721 tcatggatat tcaatggtgg cagatattat tattaacatt atatgcaggg tatcaaattt
     6781 tagatgaatt acagatttat tcttcaatga gcgccccagt ttttgcagga ttatatgctg
     6841 ggttagtaat gggtgattta aaagcaggtt taatcattgg tggaagtatg cagttgactg
     6901 ttttaggggt agggacattt ggtggtgcat caaaaatcga tgccaactct ggaacgatct
     6961 tagcaacagc tttctccatt tctctaggga tgaacccaga acaagcgatt gcggccatcg
     7021 cggttcctgt agcaagtttg atgatccaat tagatatttt ggcacgtttt gcgaatacgt
     7081 attttgcaca tcggatcgat caacatgtgg aaacaatgaa ttacaaagca attgaacgga
     7141 acttcttgat gggggcatta ccttgggcac tttccagaat ggttcctgta ttcttggccc
     7201 tagcattcgg tggtggctta gtccaaaatg ttgtggctgt tttaaacggc gacctaaaat
     7261 ggctaggaga tggcttatct gttgcagggg cagtcttacc agcagttggg tttgcaattt
     7321 tactacgcta cctaccagta aagaaacaca tttcttatct gattttagga tttacgatca
     7381 cagcgttatt agcaacagtg ttctcgaatg tccaattgtt aggaacaagt gtggctagcg
     7441 tggtcaaaga tttcccagga acattcaatt cattaccgat gcttgctgtg gcattgattg
     7501 gtctagcact ggcaacgatc agttataaga atgatcaaaa gaatgaccaa catccagtag
     7561 taagtcagca atcacaatct gatgaggggg aaatcgaaga tgacgaaatc taattataaa
     7621 ttgaccaaag aagattttaa gcagatcaat cgtagaagtt tgtttacttt ccaattaggt
     7681 tggaactatg aaagaatgca aggttcaggt tatctgtata ctatcttgcc acaacttaga
     7741 aaaatctatg gtgatgatac accagaatta aaagaaatga tgaaaacaca tacgcaattt
     7801 tttaatacgt ctaatttctt taacacgatc attactggga tcgatcttgc tatcgaagaa
     7861 aaagaaggag tctcttcaaa ggaaactgtt tctgggatga aagcaggatt gatgggttcc
     7921 ttcgctgcaa ttggtgattc tgtatttgcg gcattgatcc cgaccatatt tggagcttta
     7981 gccgcaaata tggcaacaga tggtaatcca gtaggtatcc ttatctggat ccttgctcag
     8041 gtcgctgtca tggtctttcg ttggaaacaa ctagaatttg cctacaaaga agggatttct
     8101 ctagttacca cgatgcaatc acgcttgact gcattgacag atgcggctac tttactagga
     8161 gttttcatgg ttggagcgtt agtagcaacc atgatcaatg ttaaattctc atgggcacca
     8221 acgattgggg atgtaacgtt gaatatgcaa aactatatcg atatgatctt acctaaactt
     8281 ttaccagctg gaatcgttgg tggcgtttat tggatgttag gtaagaaaaa tatgacacct
     8341 actcgagcaa tattcatcgt attgatcgta tgtgtagcat tatctgcatt aggtgtgatt
     8401 tcgaaataag ggagaattgg aaagatgagt agacaactag tcttgattag tcatggtaaa
     8461 ttttgtgaag aactaaaaaa cagtacagaa atgatcatgg gaccacaaga aaatatctat
     8521 acgatccctt tattgcctga agatggcgcg gacacgtata aagaaagatt cctctccgtt
     8581 acagcaccat tgaaagatta cgtagtgctt tgcgatctgt tgggtgggac acctgcaaat
     8641 accgtttcca agctaatcat ggaaggtgaa acgatcgaac tatatgctgg catgaatttg
     8701 ccgatggtca tcgaattcat caattcgcaa atgattggag cagaaccaga ttttattggt
     8761 tcgggtcgtg agagtatcgt ttcagtgaac caagtgattg ctggcatggg agacgatgaa
     8821 gaagaataat caagcacaac ttcttgactg gtgatacaac tggatataaa tacggatgta
     8881 taaagaggcc gtgtataaaa aagccaacgt accgcgaaat atagttttct atatttcaca
     8941 gtacgttggc ttttatcgtc ataaaatcag aaatgatctg ggtcgatcga agaagctagt
     9001 tacaaataac tatttacgct tttgctgttt accagcattc cgaccattct tcgcattgtt
     9061 ttttggtgct tgtacttgtt tttttgtttg cttcgcaggt tcagcaggtg tgacatcttt
     9121 acgaggcgtc accacttgtt ttggcggatt ttgttttaat tcttccgcaa cttgcgcttt
     9181 taatcttggt ttcatgatga cattcgtaat gaatgtttgt agacaactaa agatcccacc
     9241 gactacccag taaagagtga caccagctgg ggcactgatc gacatgaaga cgatcatagc
     9301 gggtgatacg atcaacatcg tacgcatcgt tttcttttgt tcttcaggga taccgatagt
     9361 tgagatatag ccttgaagta aataagcaat accggcaatc gctactaaaa ctaagctagg
     9421 gttacctagg tcgatcccgt aaaaggttga ttcacggatg ccttctgtat agcgagcagt
     9481 gaaatatagc gcagaaaaga tcggcatttg gatcagaagc ggtaaacaac cgataccacc
     9541 agtcatactt aagccatttt cacgataaac ttgttgcatt tcagcttgtg cagccatttg
     9601 ttcttctcga gttgtcgcag ctttcaattt ttgttgcgta gcttcaactt gtggtttcaa
     9661 tgcttgcatc ttttcagatt ggatcattgt ttttttcgat tgactaatac ctaatggcaa
     9721 aatgatgata cgaacgatga ctgtcatcaa gataacagcc cagccgtagg accaattaaa
     9781 gttttccact aaatatgtaa tcgcttgtcc cattgggtga accaatatac ggtaaatgat
     9841 tcctgaagtg tcagggttac catttgaatc catgcggaca caaccggaca agaaaagcat
     9901 gatcgtgaca agcccagagc ccaataacca atttttccat ttattcataa aatacttcct
     9961 cttttataat ttttacacaa gcttaactat actaaaaaag cgctcataat tcaatcaact
    10021 tcatagaaat ttcatagaaa taaccgattg gaggatcaaa aaagacgctt aatgttaaaa
    10081 agaagaatcc agctaaaaat acttcagtat aaagcatact tagcacctcc gttctctaaa
    10141 ataagatgag caacggatat ttccttgaaa tcataatttt agcgcaaaaa aaagaagtgg
    10201 aatgtcaatt ttttccactt cttttttttt accattgagc cgatccataa aaaagctgac
    10261 tgccatggta taaggggcta actatccctg tgtcacttgt tctaactctt tcattttctg
    10321 gacaaccagt gctggtgtga tcgtttcttt catgaagtgg atcatttcat caggtaaaca
    10381 tgcacgttca gctacggctt gatagtcact ttctgttaaa tgtaaaccca tatcagctaa
    10441 actcgttggt aagttcaagt gatgataaaa cggcagtagg tgttcgattt ctgctaattt
    10501 attttcgatc atcagctgga caaggatacc gtatgcaact ttgtttccat gaagttgctg
    10561 atggctatca gggagtacgg tcatcgcatc gtgaatggaa tgagctccag ctgttcggcc
    10621 gtagtcatcg ccaaacccac caaccatacc agccaataaa atgtttgttt ccacgacatc
    10681 gataaaagct tgattgattt tttgctggtc catcgcttcc attgcctctg cacttttctc
    10741 taaaaggatt tcgcggcatc gtaacgctgc aaattccgct acttggactt cgataggctt
    10801 gatagttaac tgagagatga ttgcgtgaga ttcataccat tttgctaagg tgtcaccaat
    10861 accggcaatc atcatctcgc gaggggagtg caaaatgatc tttggatcga tcaacactaa
    10921 atcatttgct ttagggaaca tatcatagcg aagcatcact ccttcttcat tatagaccac
    10981 actaagtgga gtataagctg cgcacgtcgc agctaaggta ggtaagatga tgattggtaa
    11041 gtttgtctta taggcaatca attttcctag atctgctact ttcccgccgc cgactgcaat
    11101 aataccattg aaatccttct ttttgcataa agaaacaaaa ctgtcagcaa gtggatcggt
    11161 acattctcca ccataatatt caaaaatttt tgttattgat aaatctggaa aaacatcttt
    11221 tactgctttc caagatgttt ttccatggag aatcaaaacg ttgtcaatat gccttttgta
    11281 aaggtgttca gggagtgaat cccatgcgtt ttcttttatt tcatactctt gaggggcacc
    11341 gcgaacaatt aaattttttg tcatataaaa aacttcttcc attatttttt taaattaatc
    11401 tttttttatt ataatagtta tgctagtata ttagcaagtt atttatgaat atttattctt
    11461 ttatagcttt tctgattaca ttattattca aaggtggcca aatggatgaa aaaaggaata
    11521 aacatattat tagtggcgct gatgtttcta ctggtttttt taccagtaaa agtacaaggt
    11581 gcagaaaaag atgaaattta cgagcggata aaacaaagtg gagaattagt cgttggccta
    11641 tctgcagact atgcgcccta tgaattccat gcgaatgtgg atggtaagga taaaatcgtt
    11701 ggttttgatg tatccattgc cgaaaagatc gcaaaggata tgggtgtgaa actaaaagta
    11761 gaagaacttg gttttgatgc attattaggt gcgttgaaaa ctggcaagat cgatttagtt
    11821 atatctggta tggcggtgac tgaagaacgt ttacaagaag ttgacttttc tgacccatat
    11881 ttcgtggtac agcaaaaagt actcgttcgt aaagaggaca aaaataaatt taagacgaca
    11941 gccgactttt ctggcttagc cgttggggcg caaaagcaaa ccacacaaga ggagttagtg
    12001 aaaaatgaac tgactggtgc agagttgacc tccctgcaaa aagttcctga tctgatcaat
    12061 aatttgctga atgaaaaagt tgaaggtgtt gtgctggaac aaccagttgc agaagcatat
    12121 gcccaacaga ataagaaagt agctttgact ccagtaaaat ttgcgcaagg cgaaaaaacc
    12181 acagctattg cgatgtcaaa aaatacacca gaactgaaaa atcatgtcaa tgcgtcaatc
    12241 aaaacgatca atgacgacgg cttgctgaaa gattatcaaa aacaagcgaa tcaattgatg
    12301 ttccaagatg atcagtcctt tcttcaaaaa tacggtccgt attatttgat tggaacaaaa
    12361 tacactattt tattagcttt tgtgggtgta ttgtttggaa tggtctttgg tagtttgctt
    12421 gcactgatga aattgggtaa gaataaattt ttaaaggcat tagccattat ttatatcgaa
    12481 tacgtacggg gaacacctct cttagttcaa atctttatcg tttacttcgg aacaggagta
    12541 ctgggattgg atctatcgaa actggtagca ggttgtattg ctgtctcgtt gaatagtgct
    12601 gcttatgtag ccgaaattgt ccgtgccggg atcaatgcgg tcaacaaagg acagatggaa
    12661 gctgcacgtt ctttaggaat ggaccagaaa gaagccatgc gtttcatcat cttcccacaa
    12721 gcaatcaaaa atattcttcc agctctagga aatgagtttg tcacgatcat caaagagtcc
    12781 tcagttgttt cggtcattgg ggtatcggaa ttgatctttc aaacgggcgt ggtacaaggt
    12841 gctagcttca aaccattcct accatatgtg ttggtctctt tgatttattt cgtgttgacc
    12901 ttcagtattt cccgtatatt agctttagtt gaaaggagaa tgggtctgaa tgcttaatgt
    12961 aaaaaaactg tcaaaaagtt ttggcgagaa tgaagtctta aaatcaattg atctttctgt
    13021 gaaagaagga gaagtagtgg tgatcattgg cccttcagga agtgggaaaa gtacaattct
    13081 acgttgtatg aatctgctgg aagaaccaac ttctggtgaa atctttttta agggacaaaa
    13141 cattacagcc cctgacagcg atatcaatca aattcgtcaa aaaatgggaa tggtatttca
    13201 aagttttaat ttgtttcccc atatgaatgt actcgaaaat ttgaccatca cacctgtaaa
    13261 aatcaaaaaa gaagacccta aaaaagcaaa agaacatgct ctatcattat tgaaccaagt
    13321 tggtctaaag gaaaaagtgg acagttatcc taccagttta tctgggggac agcaacaacg
    13381 ggtagcaatt gctcgagcat tagcaatgaa tcctgatgtg atgcttttcg atgaacctac
    13441 atctgcactt gatcctgaaa tggtcggtga agtgttggca gtcatgcagg atttagctaa
    13501 aaaagggatg acgatggtcg tggtcactca tgaaatgggt tttgctaaag aagttgccga
    13561 tcgtgtgatt tttatggctg acggcatcat tcaagaagag ggaacaccga aagagatttt
    13621 tgaaaatccg caaaatagtc gaacacagga tttcttgaac aaagtgttgt aacaaagatg
    13681 gaggaagtaa gatggacaaa agtaagattg cacgccggtt tcagcaacca gcagaaaatc
    13741 tgttgatgaa tattgctatt ttggcaaagg aaaaagagga tattatcgat ttatcgattg
    13801 gtgatcctga cttgatcact gatccgacga ttattgaagc agcttataca gatgtaaaaa
    13861 atggtgctac taattatact gcgcctgatg gcagcaaaga attcttgtca acggtcgtag
    13921 atttttatca aaagaaatat ggattgagcg ttgaatgcaa ccaagttcga gctacagtcg
    13981 gagcaatgca cgggatgtat ctagttttac aggcattact agatccagag gatgaggtca
    14041 tcatccatga accttatttt tcaccatatc gggaacaagt cattttatct ggaggcaagc
    14101 ctgtttttgt tcctacctat gaagaaaagg gcttccagtt ggatgtggaa gatttaaaag
    14161 cagcgattac ggatcgtaca aaggtgatcg tcatcaattc gccgaataat cctacgggag
    14221 ctgttttttc tgaaagcacg ttgaaaaaaa tcgctgaagt cgcaatcgaa aatgaactct
    14281 atatcatttc cgatgagatt tatgaagact ttgcctttaa agagaagttc gtaccgatgg
    14341 cgcgatttgc gcccgataat acgatcactg tcagtggtgt atcgaagggg tttgcgatga
    14401 ctggctggcg cttagggtac atgatcgcac cagcatacat caatcaaatt gctgggttga
    14461 tcaatgaaaa catcacttat tccgcaccga ctgcttctca aagaggtgca atctacgcct
    14521 taaagcacta tgaacagctt gtaccgccag ttgttgaagt attcaaagaa cgattagctt
    14581 atattgagaa aagagtggca gaaatccctt acttatcttt atcttctgtt tctggaagca
    14641 tgtatgcttt tattaatatc agtaagagtg ggctcgattc agtaacgttt gtggaagagg
    14701 ttttagaaaa aagcggcgta ctttttgtcc ctggaaaagc gtttggggaa acgatcgggg
    14761 acaactatat tcgactagca gcgactcagc cattggaaat cttaggtgaa gcctttgatc
    14821 gtttagcaaa actaaatttt tagataaaac tgtatatttg aaaacagcta tgggtatcca
    14881 ttagaacaaa gagggaaaat gatcctttcg agagttggct tgttgactgg gcagcgtcag
    14941 gatttgacaa tgaaaaagtg gtagtggaaa atcaaagtcg attttccact accataaaat
    15001 attatagact ccattttatt gaaccaaaat ttttgaagtc ctcccgcttt tacgtatgcc
    15061 tatcactggt tactaaactc gctaataaga atgttttttt gtcgatctag gatggagaga
    15121 ggggcaaact ttttcgatct acatacagac agtccgattt ttctgacatt tcctattcat
    15181 ttctagaagg tcagcctatt acaacaaact tttttctgtc ctccatcatc ggattttcct
    15241 gaaggtctac atattggaca cgtccgctgg ggcttggtga tcgtttgact tcttccacga
    15301 attttttgat tgcctcatcg tcgcccgcag cttcgatcgt gacagagccg tcatcttcat
    15361 ttttcactgt tccggtgatc cctaattgat ccgctacgat ttttgtcata tagcgaaaac
    15421 caacgctttg tacacgtcct tgcacgttca tcttgatttt gttcatttta ttcaccgttc
    15481 tttcttttat ttttaaatta atgataccga cttttttgct actgaacaag tgcaatgatc
    15541 taatccatgg tataatcagt tgaggtgaaa aatgtgaaag agatccaatc agcaaaaaat
    15601 ccaagaatca aagaattaaa aaaattacat aagaaaaaat atcgtgaaga aaaaggggaa
    15661 tatctgcttg aagggtttca cctgatcgag gaggctgttg cctcaaatgc gaaggtcaac
    15721 gaacttttta ttacgcaacg cggtctgact gagtgggcta gttggcttga agaaaatcag
    15781 gcgctttctg ttacactagt atcagaagaa gtgatggcaa ctgtttcaga tctaccaact
    15841 ccgcaaggga tcatggcagt ggtggaagct gaaaaaagag agataccgaa ttttgaaggt
    15901 ggttggttgt tgctcgacaa cgtacaagat cccggcaatg tagggacaat gatccgcaca
    15961 gccgatgctt ttggtctatc ttgtgttgta ctaggtaagg gaacggcgga tgtctacagt
    16021 accaaagtat taagaagcat gcaggggagt aactatcatt taccgatcat ccaagaggat
    16081 ctaacaaaac tattgcctat ccttaaagag caaggattta taacctatgg aacagaactg
    16141 aatgaagaag cagtgtccct gaatgatatc cagacaacag aaaattatgc gatcgtgatg
    16201 gggaatgaag gtcaaggcgt acgtccagaa gtgctggcgc taacggataa aaatgtgtat
    16261 ataccgattc aaggaaatgc ggagtcttta aatgtaggag ttgcagcggg catcatgctt
    16321 tatcacttct ccgtatagtt aaggaactat taagctttct gcattttgcg aaaacctcac
    16381 tagaatatta cgaacactag tggtatacta agttcaattt caaagataaa tggaattcaa
    16441 aaaggtggca gatcgataat tatgacagaa aaatggcgtg aagacgaaga atatatgtct
    16501 tatataaatg atctattaga aactgatgca gtaaagaaat tagcaaatta cacgcaacat
    16561 gtccactcga cacgattaga gcattcaatc agtgtgtctt actatagcta caaattagcg
    16621 aaaaaatggg gcggtgatgc aagagcgact gctcgagcag gccttttaca tgatttattt
    16681 tactacgatt ggcgtacgac gaagttcgat gaaggtacac atgcgtatgt tcacccaagg
    16741 atcgctgtga aaaatgctga aaaaatcacg gagctttcag atctagagcg tgatattatt
    16801 ttgaaacata tgtggggagc aacgattgcc cctcctaaat ataaagaagg ttatatcgtt
    16861 acttttgtgg ataaatattg tgcagtcaaa gaagcagctc aaccaatgac agcttcaatg
    16921 aaacaaaaat ggcaacgata tttcggtaaa gaacaatcga tttaaggtag ttaactaagt
    16981 atttgacccg agtattttga aaaaaatcct cgggtttttt gtttagacat tgactaattg
    17041 gtctttttag tgtttacttt gttgagatga aaaagtacat aaccaacata aaaataaagg
    17101 gggtgatgat aagatgcgat gtgtatctta tttaaaagag tttgagggct ttatctaaag
    17161 gcactttgat agaaagatca cttttttctt caaagtagcc gattttgaaa gaagaaagga
    17221 ctcaaagtca tggaaaaaac aatcaaacca tatcaatatt attttatcaa gcgagaagtc
    17281 gagcagctgt taagcgccta tagttcagtg aatgatccaa agacagtcca aacagtccaa
    17341 gcattagctg cggaaaagat ccacgaggta cttggtcatc ctaatacagc tgtaaatgaa
    17401 tttatggaaa aggtactaga cgtcactcta aaaaaagaaa aagcagaacg actattagag
    17461 gaattgaaag tgatcgttct tccattcata caaccgacaa aaccgcagat cgataaatta
    17521 ttccgaaaag tgaaaaagtt aaaacaacca gattggaatc aactggattt aagggaacat
    17581 acttatattg gttggaatga tccaggtagc caaaaaaaat ttatgatcta ttatgaagaa
    17641 gaaaaactaa aagggatcag tggaacatta tctcctacaa tcaacaaagg aatttgttcg
    17701 atttgtcaaa gaacttcaaa tgtttcactc tttctttcta ccacaaaaac tggttcagat
    17761 ggaacataca cgaaaaaagg aaattatatt tgtcatgata gtgaccaatg taatcagcag
    17821 ttggtacaat tagctccttt ttacgaattc acagaacgag tgaaacgtga gcggtgattt
    17881 cattgtattt ttctgaaaaa tatgctatct tatttggtga agtgaatagg tgatggtgtt
    17941 cgcctttaaa cgttgatcgt aagataacta atgacgccta ctaaagaaac ggggctaccc
    18001 ctttttttag taggcgtttt tttgaggagg aaatgagatg gaaaatcgat tacctgatcc
    18061 attgaaggtg atcatctata tgatcaaatg gttattgatc acagcaattt taggtatttt
    18121 tatgggaagt ttatccgcat tctttctaac tagtttgact gatgtgacag ctattcggct
    18181 ggagcatcct tggttacttt ttcttttgcc gataagtggg ggactttttg cttatctata
    18241 tacgacgtat gggggcaatt cttcccgggg aaacaattta gtgatcgatc aagggaatgg
    18301 aggaaatgaa aagattccat tacggctgat cccactgacc ttatttggca ccattaccac
    18361 gcatcttttt ggtggttctg ttggtcggga gggtacagcg gtccaaatgg gcggggcact
    18421 tgctgagaat tttgctcgtt ggctaaaatt gaacaaaatc gagcgtgaga ttcttgtcat
    18481 cagtgggatc agcgcaggtt ttagctcagt atttgggaca cccttggctg ggacattgtt
    18541 tggattagaa gtattggcaa tcggaaaagt gagaaccgaa gcactgtttc caagcttttt
    18601 tgcagcactt tttgcgaact ttgtaacgga aagtttcaat gtcaagcata cccattatca
    18661 aatgggggcg attcctgcat gggacccttc acttttcttc aaattgttgc ttgcgggcat
    18721 tgcatttggt atcattggct ggctctttag ccgttcgatc gtctggttaa aagcttggta
    18781 tgcaaagcgg atcccccatc cagttttacg caactttatt ggaggagcag tcgtggtact
    18841 cgtagtagtg attttacaga cgcaaagata tctcggatta agcttacctt tattacaaga
    18901 tgcatttaat ggaagtgctc atccttatga ttttcttggg aaacttggct ttaccgttct
    18961 atcacttggc gcgggatacc aaggaggcga agtgacccct ttgtttgaga ttggggcaac
    19021 tttaggtgcg acattagcac ccattcttca tgtatcagta ccttttttag caggattagg
    19081 gtttattggg gtgttctctg gagcaacgaa tacaccgatt gcttgctttg ttatggggat
    19141 cgaacttttt ggaggtcaag cagccagcta cttctttatg atctgtttga ttagctttat
    19201 gtgttcagga aatagtggaa tctattctgc gcaaaaagtt gaagtgaaaa aaggaatctt
    19261 gttcctaccg atccttggaa gaatctcacg acaaaaagag aaataaaaag aggttgggac
    19321 agaagtgttt aactccgaga aataagaaga aattcacgaa aattgctttt taaatttttg
    19381 tgaatttcgc ttatttccga aggagttgct tctgctccca ccgtttattc ggagttagag
    19441 tctgtggcaa aactgatttt tagttttgtc ccacgctctt ttttattgag caaatttgag
    19501 aataagagca gaaaatactg caaagccaat cattaagcca cagatgataa gatggcgttt
    19561 tttgtgtaag acaaggatgg caataaattc tcttaagata gcattcggta agtagtatag
    19621 tgcagttttt gcaccgattc cgtttgcatt gagtttcgct tgtcgcgcat atagtccagc
    19681 tctaaagata tggtaattat ttgaagtaaa aatcgcgcga taaggcccat tcatttgctg
    19741 atccattatt tcttttgaaa acagcatatt ttctagcgtc gttgtggaat tcgtttctac
    19801 taaaatatca cgctcgggaa tccctttttc taaagcatat tgtttcattg caatggcttc
    19861 agctactttt tcatcggttc cttttcctcc tgacatgagc aagactggcg gattcaaagt
    19921 tgctttactt tgtgcccaat aaaatgcgat cgccttattg atccttttag caagtagggg
    19981 agatacgcgt tcaccatcaa tcaagccagc gccgagaaca acgatataat cttggttata
    20041 ccttggacgg ttgaactgat acaaaattga aacagtcata aaattaaaga aaacgatgag
    20101 tagataagca aaaataaacg gaatgacagc aaatagagca tttgcccatt gtgggagcca
    20161 atggactaat gtatagtcca atatcaaaaa gatagtcaaa gcgactccta acaagagagt
    20221 caaaaggttg gccaaagaac gggattcttt tttcatgact acaacaccat tccaaaataa
    20281 aaaaatgatc aaaatgtaga taccgattgc caaaagaatt aatattggta tcccgatcaa
    20341 agccaataac ccaccgataa agatattttg cgtctctatt agtagccacc ctagataacc
    20401 accaaagaca atcaaaaacg tattaaaaag tacgccattg attaacctac gtttttcctt
    20461 aaaatagaaa aatgcaaaaa tactgaaaaa tagcaatgga atcaaaaaat aaaatgtatg
    20521 ataaaaaact tctaaaacga cgaagtaagt gaccatcatc ataaaagtcc acgtcccaca
    20581 ataaaagaat agagcgggat cgctttggcg cttgcgccaa tagaggatgc ctgacattcc
    20641 taaaatatag ataactaaaa atatcaggtc tctagtaaga ttcattgaat gaactccttt
    20701 cgatttgtaa attttttctt aaaaaagata gcatcattta gtagtaaata tatcgaatat
    20761 agaaaagtta gttactaaat agtcaatcag ttttttcacg acgtttctat tataacgaat
    20821 tatgttgaaa aaagctttta tcgaaaacat aaatcttcaa attaacagat tttttagacc
    20881 tcgatcatga tgaagacttt tgtagataca aataactgta acattgaaaa tgaatgcgaa
    20941 aacgatattt ttttttattg gaaaatatcg gtcaagcaat aaaccagttg cataataaaa
    21001 tgttaacggc aacaaaatct gtggaaggaa tgaaccggat gatttgatgg aaaaaacaag
    21061 atagacaaga agtatacata gtaaaacgtg gaacaagtag gccagaatga aaaatcagtt
    21121 tttatccact cgcttttcta tacattcact gtcacaaata taatcgaaag taattctatt
    21181 ttgagataaa gtattttata ggagatagta tatgaacaaa aaaagattta aacgtattga
    21241 aagaaaattt gcattaactt atgaccaagc taagtatttg aaaacactat ttccaaaaca
    21301 ggtagttcgg gataaatata gtgatcattt tatttcttcc ttgtattttg atacaaacga
    21361 tcatcacttt ttaaaagaaa tcactacaga aaagtcctat cgagaaaaat ttagaatcag
    21421 aaaatatgga gatcctcagg acatatcgcc tatctactta gagataaaaa gaaagtttca
    21481 aggaatgaca gataaacgta gaataaaatt agcgcatcat gagctcgatg atatgttgga
    21541 aaatatcgaa ttggcagaaa ccacattcag taatttagaa gaagagtata tttttaatga
    21601 aatacagtgg ttgttcagaa ggttggcatt ggagcccaaa gtatatatct attatttaag
    21661 agaagcattt gtaaatagag attcagaaga tttgcgaatc acttttgatc aaaatatcca
    21721 ttaccgtcta atgaacttaa cgacctggga acactgtaca gaagacaatc tggtagcgcc
    21781 agaaatcgat gtgctgatgg aagtaaaaac gacaggagaa atacctgaat ggttacaggt
    21841 aggattggat aggatgggta aaaaagagat aaaattttct aaatataaac aagtctataa
    21901 aagatatatc caagaggacc cgctctatgt tcaatagtgt cttaaaaaat gagccttctc
    21961 aactcacact agatgatttc tttttatgta tggtggtgtc gattttgcta ggcattctga
    22021 ttgcttacac ccatatgtat caaaacaact gtacaaaaaa cttcatgttt gccttgattg
    22081 ggttacctac tttagtacat accgtcattt tgttgatcaa cggtaactta ggcacgggga
    22141 tcgctgttct aggcgcattt aacttagtgc gatttcggtc tgctcaaggg aattcaagag
    22201 atattttcag tattttttgg gcaacgtcga ttggtttagc cacagggacg ggatatattg
    22261 tctatgcact attcgtgtct agtatagttg ctgctatcca agtcatcatc ttcacgcttc
    22321 caatcaaaaa taaacataca gtttttaata ctgaaaaaac gatcaagcta aaagtttcta
    22381 aatccttgtt tctttcgagt attattgaag aaaaaattgc agaatataca gaaaactgca
    22441 atttaaaaaa agtaaaaatc aataaagaaa cttgttcctt acactatata gtaaaagtaa
    22501 aaacgagtat gcttgaaaaa gaattggttc gaacgatcat ggatcatcca gaagtcattt
    22561 cgatcactgt aggtatggat aaatcgaata aattattgtg ataaccaaga aagtacttaa
    22621 caatgaagta agaccccagt tccaaagttt agcggggaca cttcaataaa gtactttctt
    22681 ttttgtcttc agcaactact ggtaaaactg agagcaagct ttcgtgagag tacagcgata
    22741 aagatcaacc tcccttttta tctcgagcaa tttccttgca aggctgtttc gttgatctta
    22801 aacgagttag caacagtcaa agatgcgatg gccataaaaa aattgcatta agttggctgg
    22861 tatctgatag ctgggaatct aaggaagact atccattctg tttcttaaat tccgctagtt
    22921 gatagatatc agccaattgt tccagatgat caacatcaaa gataaccgaa agatgtttcc
    22981 ttttattccc atttgcttga agagttttta tcttctcttt ggttccttca ctcaatgaga
    23041 gtgtgactaa tttctccctc gttttttctg ggaaatgaaa ggatactttg aaaaatccgt
    23101 cccaaataga aagccagaag atcggtttta ctttctgaga gtgggacaaa agtaagaaac
    23161 acttttgtct cattctttaa aaacgaataa acggtgggag cagaagcaac tccttcggaa
    23221 ataagccaaa attcacaaaa atttgaaaag caattttcgt gaatttcttc ttatttctcg
    23281 gagttaaaca cttctgtccc aacctcttgt attcaccttt tgatagccaa gcttttccat
    23341 cattataaaa ccgcaaattt caaaaaaaaa cgaacaatac aaaaagcgta ttgctcgttt
    23401 ttctcttcag tttctcacac ctaaacgact tttgtctcga cctctttttg gtgactattc
    23461 atgatgttaa aataaattac tgaaaaaatc tgtgacatgg cgccaaccaa tgacaaaaat
    23521 attagctttt tcaacagtag aagtggtaat gatgtctgtc gaaggctctt ggtttgcttc
    23581 caaatagcct aatttgtcat cagctaattg gatcgttgct gagccaactg tagtgccttt
    23641 gttgatagga gcggtcactt ggtcatccgt tactttcttt ttatcaattg ttggagtaat
    23701 cgttaatttt ccagtatcca ttccattttc gacccagact tttacagggc tttttagcgc
    23761 aacattgacg gaggtttctt ttccatcttt cactttgatg tcttttaggc ttgggatgct
    23821 tgcatttgct tttccaagtt ctttttctga ccagttgtca taacaataat ccatcaatcg
    23881 tgatgtttca ttgaatcggg cacttggatt ttcttcatgg ttatctgcat ttaaaacgac
    23941 tgtgatgatt cgtcggccat ctttgttgat cgttccgaca aagcatgcac ccgcaaaatc
    24001 agttgtgcca gtttttaatc catcgacacc ttcgtgatag tttacaaaac caggtagcat
    24061 ccagttccaa ttgaccattt caaccggtga ctgtgtgttt tcgccgaatg tttgatttgt
    24121 ggtactcgtg atttttaaga cttcaggata atctaagatg aggtgacgag caacaatagc
    24181 gacatctttc gcagacagtt gattttcatc tgtttcacca gtattctcag gtcgattctc
    24241 acctaggtaa gaattgttta aacctgatgc attgacgatc gttgcatctt tgatacccca
    24301 atcttttagt tgtttcttca ttagctcaag aaatttactt tcactgcctg caactttttc
    24361 agctaaagca accatggaag cattggctga ttggatgaaa gctgagtcaa caagttcttt
    24421 cactgtataa tcattttctt tatgcaaagg aacattcgat agatccggca cgacacttaa
    24481 tttttctgca taatccgaaa tggctacctt atcttcccaa gataatttac cctctttgat
    24541 ttgttcaagt acgatatata gaccaatgat ctttgtgatg gaagcaattc ccatcgtttt
    24601 ttcgccatcc tgatcataaa ggatttttcc actttctgca tctacggcaa aggcagcttt
    24661 ggcatttatt ttaaatgcgt cgtctgcttg aacagttgcg ctaggcaaga aagaagtgat
    24721 acataagata agacttgcta atagtacaat aaaacgggta ttttttttga acatctttgt
    24781 tctcctcatt tttaaattga ttcttacaac ttagaatatt atcagagaga acaaaaggtt
    24841 tcaatggttc tgaaaaaaac cttataaaga acaagtctta ttaatgaaga atcatagaaa
    24901 gttatctttt gggttcattg acacgaactt tgactggctg aacttcgggt tcggttaggc
    24961 gtgatgctgc aaaaagggcg cctgctgaga gtgcgaccaa actaaaaatc atgaataatt
    25021 gcataagatc acctcgttct tttttgtttt tttatagtat agcaagagag tttgaagcta
    25081 ctgttaagga aatgagcata taattgatga aagtatgaaa aaaatatgaa gtaggacaac
    25141 acaactaaaa atcgatcagg tatttctctg gtagggattc gttttattgt attgataaaa
    25201 tgggatgtgg tagactttat ttacagatac aaagaaatga tttttttagg aggggtacgt
    25261 ttatggcaaa aaaagaaaaa gaattattat cacaattgac ttcagaaggt accaaaggac
    25321 cgtttgtcac gattatgtta aacacccatg ttgcgcatca agacgtagaa aaagatcaaa
    25381 tcaaattcaa gaattttgca aaggaagcga aaaagcgctt tgaaaagaaa tactctgagc
    25441 atgattggtc tccattccaa gaaaaaatta ctagtttgtt ggacgatccg tctttctggc
    25501 gtagtgccac aacgagtgta gctgtcatag tatcaccaga acaagtgttt atccaccgtt
    25561 tgggtattcc tgtagatgac cagtattatg tgagtgatct accttattta ttagcgatca
    25621 tcaaaaatgg acatttcaac tattcatact atttattagg attgaatcgt gattcgatga
    25681 aattgtacga agtaacgaat aaacaagtca aagaagtggc tttgcctgaa gatgcaccaa
    25741 gagatgtcgt cactgcttta ggatctgaac taacaggagg cgggttgaac tacgcatcaa
    25801 atggtagtga aggtacgacg ttccatggag tcaatcctaa agatgaagaa gtcgaaattg
    25861 attgggtcaa ttattatcaa gcagtcgatg actatttgaa agatacattt gaaaatccag
    25921 agaaatggcc tatcttctta tttgcattac cagaaaatca gacgatgttc aaaaaagtgg
    25981 cgaagaaccc ttattatcgt tccgatgttg cgatctcagc ttcacctgca caactttcat
    26041 taaaagaaat tgaagcaggc gcaaaaaaac tatcgcaaga attagctgtc aaagaagcaa
    26101 gtgactacaa taagttgctt gataaaaagt tcattgatca actcgttgat attataccgg
    26161 cagcaaaaga agggaaaata tcccatttat tcattgctac atctaattta gcagatggtt
    26221 ttggcgaaga tccagaaaca gaatatgacc gccgtcaggt gctgaatgaa ctagcagata
    26281 atgtgatcac gaacggtggt caggtcttta tccttgaaca aaaagatgca ccagacgaaa
    26341 agagtttagt tgcgatctta cgttattgag tgaaaactac caaagtagat gaatggtcag
    26401 gcgttgatag aagtgtatag ctccgagaga aggagtttcc tctgtttcag ccgttggatt
    26461 catcttgagc gagagacaaa agctagcttt tgtctctcgc tcattatttt tgtgctttag
    26521 tcccattggc tttgcgaggg gaagatactt ttctcaaaaa aacgaacctt gcagttgaga
    26581 gggggataga tgcgcatact aatttttatc agttaaaaaa tgatgtggat cattagagaa
    26641 ttccaaagtt cgttcatcct ttttcagata ataaattgaa attttttgca aaagtgaaaa
    26701 tagcaaatag aaattttctg aatcttatag gggtgatttc gagaaaacgt tcgtttattt
    26761 gcaaatatat cttctaaata agagaataaa tacaaaaaaa taaggaaaaa ctctggcaat
    26821 tttgtaaacg gtatgatata gtaagaatgt agtttttgtt cggtaatctg tggtagcttg
    26881 tttcaaataa acatcttcca gatatacacc attcaagtaa ttgcaaaata tgtgttgata
    26941 cacaaggagg atttttatta tggaaacagg tacagtaaaa tggtttaact cagaaaaagg
    27001 atttggattc atcactgcag aaaacggaaa cgatgtattc gttcatttct cagctatcca
    27061 aggcgacgga ttcaaaactt tagaagaagg ccaagcagta actttcgacg ttgaagaagg
    27121 tcaacgcgga cctcaagcaa caaacgttac taaagcttaa tttacctata ttaaaaataa
    27181 aagtccagac atttatgtgt ctgggctttt ttgtcttttt ttccttaaaa agcgatgaga
    27241 gtatttttct gcactttgta gtataatttc aaaagaacat tagaggcagg agaagaggaa
    27301 gatattttga aaccaagaac ttatgcagtc gttgatatcg agacgactgg gacgaatcca
    27361 aaagaagatc ggatcatcca atttggctgc gtcatgattg aagctggtcg gatcacttca
    27421 cgtttttcga tcgatattca tccagggcgg aagatttcaa aacaaatcca gcatttaaca
    27481 gggatcacga atcaacgcgt ccaaaaagcg ccttattttg aagatgtcgc ccaaacgatt
    27541 tacaatcttt tggcagacac catatttgtc gcgcataata tttattttga ttataatttt
    27601 ttgaaccatg aactcatgcg atgcggactt cctagtttga agataccggg catcgatacc
    27661 gtagaacttg cacaaatttt cttgccgacg gaaccaagtt ttcgcttagc tgatttgtca
    27721 gaaagccttg gctttattca tgagaatcct catcaggcgg atagtgatgc cgaagtgaca
    27781 ggtcagcttc ttttactgat cgaagaacga atgaggaaat tgccgatcat cacattagag
    27841 cagattgcac gattaagtag ccatacagga atggatacga gtcgtttcat ttaccacgtg
    27901 cttgaagaaa tgaaagaaaa cccggagccc cttgatctct cattagaaat catcgatggg
    27961 ctagctttgc agaaaaaaga agtggagcta ttcacatccg tccattatgg cgagcggaca
    28021 tatccaagaa aaaaacaagc aaaagaaaaa atgtttggta aaacactgat gtatcgaaaa
    28081 gaacagaaca ggctgatgaa tgctgtctac gaccatttca caaaagatga atcaaaagat
    28141 ttgatgatcg aagcagctac aggaatgggc aaaacgattg gttatctgtt gcctttgagt
    28201 tatttggcta cacctgaaaa accagctgtc atcagcaccg tttcgcttgt tttgcagcag
    28261 cagatcatgg aaaaagacat tccattactg aatcaattgc tagatcagcc gatacaacct
    28321 gtgattatca aaagctatcg ccactatatt gatttacagc gttttaaagg tacacttgtg
    28381 gaaccgccgg gacaaaaaca atatgctttg taccaaatgg ctgtcttagt ttggctaaca
    28441 caaacgaaga ccggtgattt ggatgaatta catttaacca atctgaacca tgcattcttt
    28501 gcagatgtcg cgcacagagg cactgggttt ttagcaagga atcagtcatt ttacaaacaa
    28561 gactttgtgc gtttcttgca aaagaaaatc aaacaaagca attttttgat agtcaaccat
    28621 gcatttttag tacaagaaac acagcgaaaa gaaccattgc ttccagctag tccttatttg
    28681 ttgattgatg aagtgcatca tttgccggaa attgctgaaa aagtaaatga caaacgacta
    28741 agtattaact acttccataa acaaattcag caactggaag agccgaatca gttatttgac
    28801 cgcatacaaa gttatttgcc gaaggaacat gaagccttgc gctggttgtc gatttatcga
    28861 gaagaactct ctgcactatg cgaagcgcag atttgcgtgg cagagggatt aatgaactta
    28921 gtaagcagca agcaacctaa cggacaatat ccagaagaag tcatgatgac aaaagaaatg
    28981 ttggatcagc tgccactgga atctggaaca gcaatggatc atctgcaact tttttatcaa
    29041 gagatccaac aactacaatc acagatgcgc ttgacttttg agattatcca agaaagttgg
    29101 accaaccaga tgcggatcga tttagcaagt ttatatagct tatttgatca attagacaag
    29161 caatacttgc tgatggacca atggctagaa gactggcgag atcatttgat ccattggttc
    29221 gttcccggga atacagcaca gcagatgatt tttcatctcc ttgattttca agcagctatg
    29281 ttgccgtcaa ctgtgtggta tcctcgatat gaccatattc tttatattgg aggaacactg
    29341 aagatcggac ctaatcgaca gtatctctct aaacgacttg gcattgaagc agcacctctt
    29401 aaagtgattg cttctcctta tgattatgag aaacaggcaa gaatctatgt gccgaaagaa
    29461 gcacctgcag tccatcaagt cagcaatcaa gcatatatcg attatttaga agcagcactc
    29521 acaggattga ttgaacaaga agatcggccg atccttgttt tattcacttc tcatgatgtt
    29581 ttgcaaaagg tatatcagaa aatgcatttg tctatgctag aaaaaggacg tgaaattctt
    29641 gctcaaggat ttggcgggag tcgggaaaaa cttttgaaac gcttcatttt gtcagaaaaa
    29701 agcgtcttat ttggtgctga cagcttttgg gaaggcgtag atttacctgg agatgctttg
    29761 cagattgttg tagtcacacg tttacccttc gacaacccgt tacgtccgat ggtcaaagct
    29821 aggaatgctt atctggaatc agaggggatc aatccttttt atcaggaatc cgtgcctaaa
    29881 gcagctttga agttacgcca agcattaggt cgtttgataa ggacggagac agatcgtggc
    29941 gtattactta ttttggatcg gagattagtc actgcaaaat atggtgcacg aatcatccat
    30001 gcattaccga aaaaagtacc gataaaagag ctagctatag atgaaatcta tcaggatatc
    30061 catgaattct taaagaaaaa tgaagaagga agttaaaggt gccgtctttt ttcatcatta
    30121 aaatctgcta taatgaaaag gaatgaagat aaaggagcga cgacccttga agaaaaaaca
    30181 gacaaaggaa aaaacgatta atcgcgtgtt gcttggcttg atcgtatttt tattagcggt
    30241 catcgtgatc agctcgattt tttacttgcg ttccagtcgt ccggcggtcc aggcgaaaaa
    30301 agaagcagta gaaatcgcaa agaaatatgc aaatctcgag gaagccgatc atttttactg
    30361 gtttactcga aagaaaacgt acttttcatt gacgggtacg aatgataaag gaaaagaaat
    30421 cgccgttatc attcctaaat ctggtgaaaa agtaaaagta ttggatcaaa caaagggact
    30481 gactgaaaac gaagcaaaac agacaattgc tgcggcccat cctgaaatcc aaatcgaaaa
    30541 agctgcttta gggatgtatg atgatcagcc tgtgtgggaa gtagtaggaa aagaaacaaa
    30601 tgggaaactg aattattacc tgattggctt tgaatctgga gatgaagtca agacaatcaa
    30661 gggaatttaa aaggtaaagg aatgaatggg atggagttat caaaaagaac aaaacgatta
    30721 gaaccgtctg tcactttggc agctgcggca aaggccaagg cattaaaagc aaaaggcaga
    30781 gatgtgctga gtttgactgt gggagaaccg gattttgcga caccagaaaa catccaagaa
    30841 gcagcaatcg aagcaatccg caatgggaaa gctagctatt atacaccaac agcaggaatc
    30901 ccagagcttc gacaggcaat cgttgattat ctgaagaaaa actatggact tgtctatgaa
    30961 ccttcacaaa cagtcgtaac agacggagcg aaatttgctt tgtataccct tttccaaacg
    31021 atccttgacc cgcaagatga agtcatcatt cctgtgcctt actgggtcag ttacggtgag
    31081 caagtaaaac tggcagaagg acttcctgtc tttgtgaaag gggaagaatc caatagctgg
    31141 aaagttactg ttgagcagct agaacaagca cgttcagaaa aaacaaaagc cgtaatcatc
    31201 aattctccat cgaatccgac tggaatgatt tatagcaaga atgaactgca ggcaatcggt
    31261 gaatgggcag taaaaaatga tattttgata gttgctgatg atatttatgg ccgtttagtt
    31321 tataatggca atgagtttac tccaattgca acgatttcag aagcaatcaa aaatcagacc
    31381 atcatcatca atggcgtgtc taaaacatat gcgatgacag gctggcgcat tggttatgcg
    31441 gtggggaatt ctgagatcat caatggaatg attgctgttg cttcccagtc aaccagtaat
    31501 ccgacagcag tcagtcaata tgcagctgtt gaagcattga aaggcgagca agatacagtg
    31561 gaagaaatgc ggaacgcctt tgaagaacgc ctgaatacgt tatatccgct tgtggcagaa
    31621 ctgccgggtg tttctcttga aaagccacaa ggagcttttt atctttttcc taatgtaaaa
    31681 gaaacgctac gcatgtgtaa atatgaaaat gtcacacaat gggtagaaga tcttttagaa
    31741 gaaacagggg tagcgcttgt gactggcgaa ggctttgggg caccagaaaa tgtccgcatg
    31801 agttatgcca ctgatcgcgc tacgttagaa gaagcggtac gcagaatcaa gcaatttatt
    31861 gagagtaaaa gtcaaaatta atcctgaaga aattcaagga atataaaagg agagtcatac
    31921 gtggaacaaa ttcaaatcat cgattcgaaa aaccatgtgg gagaaacagt aacaatcggc
    31981 gcttgggtcg caaataagcg atcaagcgga aaaatcgcat ttttgcaatt aagagacgga
    32041 acagcctttt tccaaggtgt agttgtaaaa agcgaagtgc cggaagaagt tttccaaaca
    32101 gctaaaaatc tacaccaaga aacatccgtg ttagtaactg gagaaatccg tgaagacagt
    32161 cgttcaaaat ttggttatga aatcggaatt acaaatgtgg aagtggtaag cgagagccac
    32221 gattatccga tcacaccaaa agaacacgga acagacttct tgatggatca tcgtcattta
    32281 tggctgcgtt cttcaagaca acatgcgatt atgcagatca gaaatgaaat cattcgtgca
    32341 acgtatgaat tctttaatca acatcatttt gtcaaaatcg atccgccgat cttgactggt
    32401 tctgcaccag aaggcactac ggatctattc gaaacaaatt actttgatca aaaagcttat
    32461 ttatctcaaa gtggccaatt atacatggaa gctgctgcta tggctttcgg aaaagtcttt
    32521 tcattcggtc cgactttccg tgctgaaaaa tcaaaaacac gacgtcattt gatcgaattc
    32581 tggatgatcg aaccagaaat ggctttcact catcaagaag aaagtttaga agtacaggaa
    32641 caatatgtag cattcttagt acaaaatgtt ttagatcatt gcgaatacgc attagatgta
    32701 ctaggacgag acaaagaagt cttaaaaact tatacaaaat tgccattccc tcgtattact
    32761 tatgatgatg cgatcgaatt actgaagaaa aatggatttg atgacatcga atggggcgaa
    32821 gactttggtt cacctcatga aacgttcatt gcgaattcat tcgaacagcc tgtctttatc
    32881 ctaaactatc caaaagccat caagccattc tacatgaaac cacatccaac aagagaagac
    32941 gtggtgatct gtgcagatat gatcgcacca gaaggttacg gtgaaattat tggtggaagc
    33001 gaacgggcaa cagactatga tttcttgcta gaacaaatcc gtaatcacgg tttggatgaa
    33061 aaagaatatt catggtatct tgatctacgt aaatacggtt ctgttccgca ctctggtttt
    33121 ggtctaggcc ttgaacgaac agtcacttgg attgctggta tcgaccatgt gcgtgaagct
    33181 attccattcc cacgtttgtt gaaccgaatt tatccataag aggttgtgaa atcagtgcct
    33241 tgacctgagt attagagaaa caaaacggaa aaatagcttc tcatatttta ctgttttttg
    33301 agctaatatc gagggtcagc tgattgaaca ccgtttatat caagaggttg tgcgtctgcc
    33361 gttcagctcc gagtcacaag gagtaatttc aaaaaaacat tttttcatgt ttgatgacta
    33421 ttgtgacttg tgaccaagga gttggccgga gagcaacgtt tatttaaaaa aaaggctctt
    33481 tgtcaaatag gactgataga gtgagataag aacatctaag gtagaattcc ttttctactt
    33541 tagatgtttt ttgattcata ggtaatcaga ttatttagta agaaaattct ggtcttcatt
    33601 ttccgaaagc ttcgaaagcc ataagcgact cgtttcaatg ctttgatgtg ggtatgcaga
    33661 ttttctattt tggcatttga ataaggcaat tcgagggcta aacgaatgcc ggattcatag
    33721 tttataaaag ctttttttat agaatgcagt tcttttggaa cggaattggg catcgttctt
    33781 acaagtttaa agaaagtgtc cgcctctttg tcgtgaaacg cttgaagaat ttcttgatag
    33841 taaaaatagg cgattcgtaa ttcgtcagag atcgaaagca gacgatccac cacttcactt
    33901 tcggtgagat acgcccaacc aaaattgcgc catttggtcc atttgtcata aacaagcttg
    33961 tcctgtcgtt tgatcagaag ccgagacaac gcctttaatt gtcgataata tttggcttgt
    34021 gttggatcgt ttcgatcaaa gcttttcatg attcgtacgc gaatatcctc aaatttacga
    34081 atgagatgtt tgacaatgtg aaaacgatcc acaacgagtt ttgcctttgg aaaacattcc
    34141 tttatcagag aggcataaga aacattcatg tccgtcacga tgacctttac cttcaatcgt
    34201 gcgcgtcgtt caaattgcat aaaataagaa acgagagcct ttttcttccg tgaaggaaga
    34261 atatccagta attttccagt atcgccatcc atacaagaaa aggagtaggg accgacttga
    34321 tttttcagtg aacgaaattc atccattaat aaacaacgcg gtaaccaatt tctttttact
    34381 tttgtcatgg ggatcagaga agcgagtgtc cgagaaacgg tcgaccaaga aacgccgcaa
    34441 tgcttagcaa ttgtcgtcat tgcttgtttt tcagttagct cttctaaaat tttatagcgc
    34501 acttgtttag cgataaagca gtttctatcg acaatgtagg tattcgccgt aaaataggtg
    34561 tggcagccac gacagtggta gcgttgtttc gctaaagcaa gataagtcag ttggttcgca
    34621 catttattaa gttgaatgag cgattttttc tttccgttct taacgatcat gccttcatga
    34681 ttcatctgtt tacacaaagg acagcgacga atttctttac ttaacgtcgc agaaacaaca
    34741 agactcttga tattcttaat gctcttcgat tccacatttg tgatgaaaat gtttttatct
    34801 ttgattccaa gtagtagttt gatatgatga agatcaggca tacagaacgc tcctttgatt
    34861 gtgttgtggt gattc
//
LOCUS       DAZULR010000029        34586 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.029, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000029 DAZULR010000000
VERSION     DAZULR010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34586
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.029"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            212..604
                     /locus_tag="ACG8ZV_001613"
     CDS             212..604
                     /locus_tag="ACG8ZV_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFS4996956.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="ACG8ZV_001614"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="ACG8ZV_001614"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HFS4996957.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            2698..2943
                     /locus_tag="ACG8ZV_001615"
     CDS             2698..2943
                     /locus_tag="ACG8ZV_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996958.1"
                     /translation="MKEKDCFYDKLYKLLLQVGKSSSLLGGILSIIMFVLFFYLLFHL
                     KFFSNDFLICLGLTLAMFISSLLCGLNFFCTHKGLKK"
     gene            3165..4775
                     /locus_tag="ACG8ZV_001616"
     CDS             3165..4775
                     /locus_tag="ACG8ZV_001616"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HFS4996959.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            complement(4752..4964)
                     /locus_tag="ACG8ZV_001617"
     CDS             complement(4752..4964)
                     /locus_tag="ACG8ZV_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996960.1"
                     /translation="MKMKIFKKFFAKNKISNSALIEKSLLLSIFFPTNNNKSEKEKSD
                     KKIAYPLLLLLFSFYQVQKLFCFVIC"
     gene            5067..5936
                     /locus_tag="ACG8ZV_001618"
     CDS             5067..5936
                     /locus_tag="ACG8ZV_001618"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HFS4996961.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="ACG8ZV_001619"
     CDS             6101..7372
                     /locus_tag="ACG8ZV_001619"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFS4996962.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLITTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /gene="rho"
                     /locus_tag="ACG8ZV_001620"
     CDS             7369..8664
                     /gene="rho"
                     /locus_tag="ACG8ZV_001620"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008186 - ATP-dependent activity, acting
                     on RNA [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HFS4996963.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="ACG8ZV_001621"
     CDS             8763..9026
                     /locus_tag="ACG8ZV_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HFS4996964.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="ACG8ZV_001622"
     CDS             9471..9920
                     /locus_tag="ACG8ZV_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFS4996965.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="ACG8ZV_001623"
     CDS             9977..11395
                     /locus_tag="ACG8ZV_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HFS4996966.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="ACG8ZV_001624"
     CDS             11395..12255
                     /locus_tag="ACG8ZV_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HFS4996967.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13202
                     /locus_tag="ACG8ZV_001625"
     CDS             12429..13202
                     /locus_tag="ACG8ZV_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFS4996968.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13349..13714
                     /locus_tag="ACG8ZV_001626"
     CDS             13349..13714
                     /locus_tag="ACG8ZV_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HFS4996969.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13862..15070)
                     /locus_tag="ACG8ZV_001627"
     CDS             complement(13862..15070)
                     /locus_tag="ACG8ZV_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4996970.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15089..15367)
                     /locus_tag="ACG8ZV_001628"
     CDS             complement(15089..15367)
                     /locus_tag="ACG8ZV_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996971.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15560..16216
                     /locus_tag="ACG8ZV_001629"
     CDS             15560..16216
                     /locus_tag="ACG8ZV_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFS4996972.1"
                     /translation="MDSRVLKEYLDKNDFPIIRKGYHKYLTFEGMEDSHTYILKEGTV
                     KASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESEYAEFYRINRVRFW
                     QNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLYELYDLFGVRTEEG
                     MLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIVILNMDLLEDNIIF
                     "
     gene            complement(16658..17455)
                     /locus_tag="ACG8ZV_001630"
     CDS             complement(16658..17455)
                     /locus_tag="ACG8ZV_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HFS4996973.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17452..18636)
                     /locus_tag="ACG8ZV_001631"
     CDS             complement(17452..18636)
                     /locus_tag="ACG8ZV_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HFS4996974.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18661..19908)
                     /locus_tag="ACG8ZV_001632"
     CDS             complement(18661..19908)
                     /locus_tag="ACG8ZV_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HFS4996975.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20123..21868
                     /gene="dnaX"
                     /locus_tag="ACG8ZV_001633"
     CDS             20123..21868
                     /gene="dnaX"
                     /locus_tag="ACG8ZV_001633"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HFS4996976.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21888..22202
                     /locus_tag="ACG8ZV_001634"
     CDS             21888..22202
                     /locus_tag="ACG8ZV_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HFS4996977.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22227..22823
                     /gene="recR"
                     /locus_tag="ACG8ZV_001635"
     CDS             22227..22823
                     /gene="recR"
                     /locus_tag="ACG8ZV_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HFS4996978.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22887..23531
                     /gene="tmk"
                     /locus_tag="ACG8ZV_001636"
     CDS             22887..23531
                     /gene="tmk"
                     /locus_tag="ACG8ZV_001636"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HFS4996979.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23546..23875
                     /locus_tag="ACG8ZV_001637"
     CDS             23546..23875
                     /locus_tag="ACG8ZV_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HFS4996980.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23889..24827
                     /gene="holB"
                     /locus_tag="ACG8ZV_001638"
     CDS             23889..24827
                     /gene="holB"
                     /locus_tag="ACG8ZV_001638"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HFS4996981.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24863..25687
                     /locus_tag="ACG8ZV_001639"
     CDS             24863..25687
                     /locus_tag="ACG8ZV_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HFS4996982.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25680..26027
                     /locus_tag="ACG8ZV_001640"
     CDS             25680..26027
                     /locus_tag="ACG8ZV_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HFS4996983.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26096..26968
                     /gene="rsmI"
                     /locus_tag="ACG8ZV_001641"
     CDS             26096..26968
                     /gene="rsmI"
                     /locus_tag="ACG8ZV_001641"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HFS4996984.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27077..28180
                     /gene="dinB"
                     /locus_tag="ACG8ZV_001642"
     CDS             27077..28180
                     /gene="dinB"
                     /locus_tag="ACG8ZV_001642"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HFS4996985.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPL"
     gene            complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="ACG8ZV_001643"
     CDS             complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="ACG8ZV_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HFS4996986.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="ACG8ZV_001644"
     CDS             complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="ACG8ZV_001644"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HFS4996987.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31684..32451
                     /locus_tag="ACG8ZV_001645"
     CDS             31684..32451
                     /locus_tag="ACG8ZV_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4996988.1"
                     /translation="MEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGEFVGIMGPSG
                     AGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQEFNLIDTLN
                     AKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQRIAAARALV
                     VQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTASYCDRILFIK
                     DGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32441..34483
                     /locus_tag="ACG8ZV_001646"
     CDS             32441..34483
                     /locus_tag="ACG8ZV_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4996989.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
BASE COUNT        11117 a         6131 c         7258 g        10080 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat tactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgactt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt tgagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aagcttttag aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac
    13081 ataaattcat gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag
    13141 aactgacaaa agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat
    13201 aaattattac gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc
    13261 tcgcttctct cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt
    13321 ttttatccag gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc
    13381 aatcatgatc tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat
    13441 ggattcaacg attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt
    13501 gatcttacgt aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt
    13561 tatcttgtgg ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt
    13621 gattcctgct ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca
    13681 aggcatcgta ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga
    13741 taaatgaaag ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta
    13801 ctcaaaaaac cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag
    13861 atcaaatttc atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc
    13921 ggccattaac aagatagagt gctgtacata tcaatggaat gactccggca atcacataca
    13981 atcctctaaa tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc
    14041 ctaggtctaa accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga
    14101 tttttaaaca aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg
    14161 ctccagagat aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg
    14221 ttaagaataa atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc
    14281 cagtcaatgg acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag
    14341 cagcaactaa gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag
    14401 aaagacccat caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat
    14461 tgatattcca tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag
    14521 gaaagacaag gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga
    14581 aacgaaaatc agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta
    14641 aactagtact taatccataa taattgatgc cttccccttt tttagatgca gggatatatg
    14701 cagtaacgat agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc
    14761 gaactaaata caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat
    14821 agaagatcgc gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca
    14881 tgaataagcg tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc
    14941 tcaagctggc gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat
    15001 aaatcaggta gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt
    15061 tcttttccat gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt
    15121 gaacttctac atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat
    15181 ctcttgtaga cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca
    15241 ctgctttgat caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt
    15301 tcatatcaaa tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt
    15361 aattcatgtt ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa
    15421 aaaaggaaaa aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta
    15481 gtaaaatacc tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag
    15541 tttggatggg ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga
    15601 ttttccgatt atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc
    15661 ccatacgtat atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag
    15721 agaatttaac cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata
    15781 ttcacaattc atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta
    15841 tcgaatcaat cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta
    15901 tgtaaaagag tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct
    15961 attaaacgga aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg
    16021 tgtgcggaca gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa
    16081 attttgtggc atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga
    16141 tggtattatc accgttaaag accatcatat cgttattttg aatatggact tgttagaaga
    16201 caatattatc ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag
    16261 agaaacaaac ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt
    16321 cagctgattg aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca
    16381 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg
    16441 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
    16501 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
    16561 agatgtaagc ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt
    16621 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
    16681 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
    16741 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
    16801 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
    16861 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
    16921 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
    16981 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
    17041 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
    17101 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
    17161 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
    17221 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
    17281 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
    17341 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
    17401 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa
    17461 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
    17521 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
    17581 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
    17641 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
    17701 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
    17761 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
    17821 atactggctt ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat
    17881 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
    17941 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
    18001 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
    18061 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
    18121 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
    18181 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
    18241 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
    18301 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
    18361 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
    18421 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
    18481 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
    18541 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
    18601 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
    18661 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
    18721 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
    18781 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
    18841 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
    18901 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
    18961 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
    19021 ggctgcttcc ataccacgtg caatggaacc ttgcacgtat ccttcacgta cgctaggatc
    19081 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
    19141 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
    19201 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
    19261 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
    19321 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
    19381 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
    19441 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
    19501 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
    19561 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
    19621 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
    19681 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
    19741 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
    19801 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
    19861 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
    19921 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
    19981 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
    20041 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
    20101 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
    20161 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
    20221 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
    20281 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
    20341 caacgaatgc gaaatgtgtc gatcaattac tgccggtacg caagaagatg tgatcgaaat
    20401 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
    20461 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
    20521 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
    20581 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
    20641 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
    20701 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
    20761 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
    20821 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
    20881 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
    20941 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
    21001 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
    21061 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
    21121 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
    21181 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
    21241 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
    21301 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
    21361 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
    21421 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
    21481 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
    21541 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
    21601 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
    21661 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
    21721 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
    21781 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
    21841 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
    21901 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
    21961 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
    22021 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
    22081 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
    22141 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
    22201 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
    22261 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
    22321 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
    22381 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
    22441 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
    22501 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
    22561 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
    22621 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
    22681 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
    22741 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
    22801 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
    22861 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
    22921 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
    22981 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
    23041 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
    23101 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
    23161 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
    23221 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
    23281 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
    23341 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
    23401 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
    23461 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
    23521 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
    23581 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
    23641 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
    23701 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
    23761 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
    23821 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
    23881 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
    23941 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
    24001 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
    24061 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
    24121 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
    24181 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
    24241 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
    24301 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
    24361 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
    24421 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
    24481 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
    24541 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
    24601 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
    24661 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
    24721 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
    24781 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
    24841 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
    24901 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
    24961 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
    25021 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
    25081 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
    25141 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
    25201 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
    25261 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
    25321 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
    25381 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
    25441 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
    25501 gacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
    25561 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
    25621 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
    25681 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
    25741 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
    25801 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
    25861 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
    25921 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
    25981 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
    26041 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
    26101 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
    26161 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
    26221 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
    26281 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
    26341 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
    26401 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    26461 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    26521 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    26581 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    26641 gaatttctta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    26701 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    26761 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    26821 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    26881 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    26941 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    27001 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    27061 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    27121 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    27181 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    27241 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    27301 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    27361 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    27421 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    27481 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    27541 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    27601 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    27661 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    27721 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    27781 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    27841 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    27901 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    27961 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    28021 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    28081 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    28141 ggacccgatg acttatgaaa acatcgtcct tccattatga gaaaatcaag aaatataaaa
    28201 acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa
    28261 gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac
    28321 aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg
    28381 aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat
    28441 ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc
    28501 tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg
    28561 cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta
    28621 atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata
    28681 tcggaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac
    28741 gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat
    28801 atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa
    28861 acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat
    28921 aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga
    28981 gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct
    29041 cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg
    29101 aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt
    29161 tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc
    29221 atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt
    29281 tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca
    29341 ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt
    29401 ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg
    29461 tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc
    29521 aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat
    29581 tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg
    29641 tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc
    29701 catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct
    29761 gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag
    29821 cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa
    29881 agacgtttcc cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct
    29941 ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt
    30001 aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat
    30061 gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac
    30121 ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt
    30181 ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt
    30241 ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc
    30301 agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa
    30361 attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg
    30421 aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa actttgcata
    30481 gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa
    30541 tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca
    30601 agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca
    30661 ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca
    30721 ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc
    30781 atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca
    30841 tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc
    30901 agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt
    30961 tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca
    31021 aaatctcgtt tggtacgata attgatgtac tcttctgcta attcatattc gtttttttct
    31081 agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg
    31141 cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt
    31201 gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca
    31261 tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc
    31321 tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt
    31381 gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag
    31441 tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa
    31501 aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa
    31561 aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa
    31621 ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa
    31681 gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct
    31741 cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt
    31801 atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg
    31861 cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag
    31921 ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat
    31981 accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag
    32041 gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa
    32101 cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt
    32161 gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg
    32221 gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg
    32281 ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat
    32341 ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta
    32401 atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt
    32461 taaaagtttt tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc
    32521 cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc
    32581 aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt
    32641 tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat
    32701 aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga
    32761 aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc
    32821 caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt
    32881 tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt
    32941 atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa
    33001 agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat
    33061 cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc
    33121 atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt
    33181 tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat
    33241 catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa tgggtaacac
    33301 gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat
    33361 ttctttaatg acaattggcg gcacggctag tatctctact attttatcct accaggagaa
    33421 agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat
    33481 tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg
    33541 gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga
    33601 aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc
    33661 acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata
    33721 tggatctagt attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag
    33781 tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt
    33841 ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa
    33901 taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt
    33961 ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact
    34021 tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc
    34081 ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac
    34141 actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt
    34201 agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca
    34261 aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat
    34321 attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc
    34381 cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta
    34441 tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa
    34501 gataataaat agaactaaat tttgaatacc atttatttgg aataagaggt tgtgacacga
    34561 tttttgtcac aacctcttta tttttt
//
LOCUS       DAZULR010000030        32817 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.030, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000030 DAZULR010000000
VERSION     DAZULR010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32817)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32817)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32817
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.030"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            5..244
                     /locus_tag="ACG8ZV_001647"
     CDS             5..244
                     /locus_tag="ACG8ZV_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996990.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKDVFKSLSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            311..550
                     /locus_tag="ACG8ZV_001648"
     CDS             311..550
                     /locus_tag="ACG8ZV_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996991.1"
                     /translation="MNYEEIENRKKVSKEMEEKLLKMMKQKHLKRLSVMQYINDMKIT
                     GKEKACLLGSMKNFEQLRRTYVKTGSNCQLLLEVS"
     gene            677..1366
                     /locus_tag="ACG8ZV_001649"
     CDS             677..1366
                     /locus_tag="ACG8ZV_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HFS4996992.1"
                     /translation="MNKNNKTLFNPYVGVIIVFLLFSYFAYQGYQKDKIAEKVDGVTK
                     TIHIQEQAKTYQDNLTSLTDISKRQLITNQKQALEKDLKGEIAGKLVFSSTGFILPVF
                     QGANSDTLSLGVASTYYLDTEMGNGNYILAGYNVDTPSVLLSDMTDLSEGEEIDLIDA
                     HYKYQYEVSKRGKISDYSQVVQSKENNSFLSLPKAGKKPLLTLLAFQANNMKKCDVIQ
                     CELVNVEKINK"
     gene            1372..2538
                     /locus_tag="ACG8ZV_001650"
     CDS             1372..2538
                     /locus_tag="ACG8ZV_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HFS4996993.1"
                     /translation="MSHIQELVEKLINKMSAIFLLLLVSILYLIWTVGLNPPTILFIY
                     DNAAQLVTFFVGCLFLLNLYKVKRNDLFFIAAGILFYLFFSFFRSYRGDTFYGDLIVP
                     TIIAIILIVKWTKFTVIDRSLYLVVFYVFLLVTVYRVFTEIPVPEGQSIWNPSNKLSD
                     IWINTNTIGSSLMTLALLITGFASSFGKWYMRLLSLPALILAGATIWVCQSKAALYAL
                     VIFIILEILPKKVFRNTHLSFWMYAAVSVLALPISYFAAMSDKVHLFTGREEIWRKFY
                     ETLGEKTGQIFVGMKPFFFHRGNQILGNHNTYHALVNHYGLIGFVLSIILLLSFLWLL
                     VRKRELTNGQLTFLWAFLAIMCQSFMEETLTTISWVPIVFLMLAMATHQYKTTR"
     gene            2620..3291
                     /locus_tag="ACG8ZV_001651"
     CDS             2620..3291
                     /locus_tag="ACG8ZV_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HFS4996994.1"
                     /translation="MKKWLFGFLGVALIVVCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPEYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            3344..5320
                     /locus_tag="ACG8ZV_001652"
     CDS             3344..5320
                     /locus_tag="ACG8ZV_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFS4996995.1"
                     /translation="MAINRYVKKAGMIVGMLGIIAGCFQGYRAYAEDVTQKTPPERVN
                     ITVHKLMYDQSTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PTEDSDLTNAKVDEIVKDVEDKGSNSEYVKNATNKITSAVDENGEITFADQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDNTGSGFLKDIHLYPKNIVSKLSFELTK
                     FGDDGTAQSKQTPLKGAKFELYKGEPGKGTKLGELVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDQEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGEEHSFQIGDAVNYQGTIHIPTDIAGGTDGITVNGVKSETSPYSVFKWGDTA
                     GKGLSYVAEKADIKVTNNDGSVVLKENTDYKIENSDSGFVIDFIVNNGQVSDTVANLH
                     GQDLKMTYNMFVNDSAEIANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLTDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGDYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQSYVLISCLLLGAGAISAVVYFKKKA"
     gene            5333..6085
                     /locus_tag="ACG8ZV_001653"
     CDS             5333..6085
                     /locus_tag="ACG8ZV_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFS4996996.1"
                     /translation="MIIRHPKKKRIMGKWIIAFWLLSAVGVLLLMPAEASVAKYQQNQ
                     QIAAIDRTGTAAETDSSLDVAKIELGDPVGILTIPSISLKLPIYDGTSDKILENGVGI
                     TEGTGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGEKFYIKVDGEQHAYQIDRIE
                     EVQKDELQRNFVTYLEPNPNEDRVTLMTCTPKGINTHRFLVYGKRVTFTKSELKDEEN
                     KKQKLSWKWLLGSTVFLSVMIIGSLFVYKKKK"
     gene            6101..6862
                     /locus_tag="ACG8ZV_001654"
     CDS             6101..6862
                     /locus_tag="ACG8ZV_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
                     /protein_id="HFS4996997.1"
                     /translation="MRNRKWLFVCAAALFSFTAYTQLTFADRQESTDSTEQTIQTSDS
                     STIQSSDETVDSSTVDSSEEPKIAEDDQIVKQTIHVQKIISSEQLDNQGQKLEKQEGV
                     NGAKFSVYDVSDILQKMDVKDLTTDQIESQLKDRVKKLSSDQLKLISNGETKTIDQQT
                     GVFEFSVEVQANQKQAYYIVNESSPENISNSEDILLLTPVSDKNGEFLKDVWIYPKSE
                     ASQPKEEVKKIVSTGVKKNFFENCWDFVTHLFSRD"
     gene            6875..7135
                     /locus_tag="ACG8ZV_001655"
     CDS             6875..7135
                     /locus_tag="ACG8ZV_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4996998.1"
                     /translation="MKLIKLLLFNFSCLTAVFLYCGLLFSKLSILPSYQLYLMRILNI
                     PAASMPLDIMEKLIRNPLFTTINLIVIVGISLVIYKKEGMKG"
     gene            7132..9222
                     /locus_tag="ACG8ZV_001656"
     CDS             7132..9222
                     /locus_tag="ACG8ZV_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HFS4996999.1"
                     /translation="MNFKHSWTRRLKYVFPIMMMLGTLFGLKTANVFAEKVIVDPSNP
                     IQNVKNNFIIPKDVPNAKTNITVNGASKVYKYHVDANKGGFTDDYVGLVEGNKNIRYP
                     SFQKEYGETNLVLEGVTTNTKVNIDYGKIGTYNGKKVNIKLVLSNIHLYSDTLPWNLL
                     DNNYTKTHFRDDGYKNTNGAMSKSKKRTVLWISDNLFSGIVYHSTQMNVQLVATYEDG
                     SPVQFSGDTFISFNSLNPAGGKSTDLKGEYAHYDKMNTTDWYVRKDTVLSEFKSFYNN
                     LNVVGGHPGGSSKLTQADNDFNNLHDKLGDPKFGQGTVSFKISEANPTFVIGSSNVQT
                     WFTLSSATIFSVVPDQPEKTGVDKNGNNVNDKMLQVGDTIQYRIKQKVNRLGVDLLAV
                     YDRFELIDNLPKEVNYVDAHVESGTNKKFDVSGEVTYDKTKHQVKYAAKADTLKNRMK
                     YNGETYELVINVKVNELANQNSVAKNQGTSIINKVEKDTNIITVYFPKIPVKEVQQNG
                     KDVNGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDAASDHYKQFSIQDPIEARLT
                     YKEGSAQVIDKSKGKDITSEGTLTYDSNSRTLKWEASADFLNNNLLDGREIQLIFTAK
                     TPLQSEKNIDNQAVVAVDNVSNKTNVVTIGVDPNLPQVIVPKTGSTHLVTILAVSLLL
                     LVLATFGYAVLKFN"
     gene            complement(9258..11315)
                     /locus_tag="ACG8ZV_001657"
     CDS             complement(9258..11315)
                     /locus_tag="ACG8ZV_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HFS4997000.1"
                     /translation="MKLLNPKTVIAIGTFAATVALAGSADAASTNVMYRLYNPNNHEH
                     FYTSSTKERDHLVKIKWGNYEGPAWEAPTSGGHLVYRLYNKGLRDHHYTASWDEVKWL
                     TKNYGWTYEGPAWRSAEKNNKPIYRLFLPGVTSGSHHYTASWKEVQWLTKDYGWKYEG
                     IGWYGADTSKPKVNKSALEALYTSVKGTKKGDYTDNTWNAFQTALNNAKKVLNDSKAT
                     QKQVDSAKNTLDSAYKGLKKKPAPTVNKTELQALYNQVKSTAKGDFTEGSWNNFQTAL
                     SNAKKVLDDSKASQTQVNNAKNSLDSAFKGLQHKPKPSEYAVTVRHMNRQTGTLLKEE
                     HVSVKAGTSYTAKARTDLTNFEAPQYQVNGNETQTQTINTNTTFTFYYDEVFLVEVKA
                     RPNKVSDTDPNIQELYNYSKSYPVVYGQSITIEAPMFTNFVLDPRESSSNTVTLNNVT
                     SNQGINFAYTHQYNVTVNHINVDTNAVLSTETQTVYEGDSFSTSWKNMTDQNYFLCRN
                     DDSSVTVDKNGQRVINNVDQNRTITFKYKNISLSDLNNYVRQKELAWLNSYRQQNGVA
                     PMQFNDIVQQAADIRAKELQVSFSHYRPGGGTFQDLLESLGCYGAKGENINSFYLYVD
                     EILSDTGAVNAMVMWKDSAAHNANLLYNNQSIVGLSHAYEVSADGSLSSDNVFISANP
                     IFK"
     gene            complement(11460..11651)
                     /locus_tag="ACG8ZV_001658"
     CDS             complement(11460..11651)
                     /locus_tag="ACG8ZV_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997001.1"
                     /translation="MYADKEKIEWLLFETGKTAYEISKHSSVAESTIADLIKKKSAIE
                     KMRFDNAAKLTKYAESISS"
     gene            11839..12294
                     /locus_tag="ACG8ZV_001659"
     CDS             11839..12294
                     /locus_tag="ACG8ZV_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997002.1"
                     /translation="MKKLIMVFTSLIAMIVILGGCGSEKNKQDSQDNGVLKPGTVWKE
                     EVGGLVHNLKIIDDTTWEYSESVWHPEQVQITVEKLKDYKGLERYKVIDSGGVDLFIG
                     KTALIVPYNKDGLETFKFIPTNEKEHRDKSEILKEYSTKSGYKLQKTSE"
     gene            12291..12533
                     /locus_tag="ACG8ZV_001660"
     CDS             12291..12533
                     /locus_tag="ACG8ZV_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HFS4997003.1"
                     /translation="MIASLFIYPEGGIAVAKAKTPFEKAASKILERRGVSETQWKQEV
                     LEKAQFDLLRGKDKDLEGYIYQREREKLVFDEIIKH"
     gene            12551..12853
                     /locus_tag="ACG8ZV_001661"
     CDS             12551..12853
                     /locus_tag="ACG8ZV_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997004.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQGAATSLKNNLMIFAAVAA
                     VASIVLGGIFFFFGRRGAENGKMHVGYVLMGVGVILAAASIVVSLFGMFGQTPQGL"
     gene            12922..14976
                     /locus_tag="ACG8ZV_001662"
     CDS             12922..14976
                     /locus_tag="ACG8ZV_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997005.1"
                     /translation="MYFTISGNTKKDKELIKKATKKVGKRTAFLPKTIKYSVIETEEQ
                     LHVLGQVLEQENQSSVKLTLTLHDKEGKIEKAGTEYVFGPLDYQISEGFYPTLMDLIR
                     LDVFKETDETMSVEESYRNEKLLQVLEEELESDQRKVSQVSEVEVNDEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMGQLEVDPFEETMEDEETAEVEVDLVEA
                     NEEPTWTEGDSQEYIEPLISEEVEKNETEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWERTKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCIE
                     KINNFTKTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTT
                     TEVLMERHGQIQQELQAQIPKWKKEYEIQQQELKEQEEKQRQEEKEREQLELKKREQH
                     LAEQKVAIEKQRLEQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPVAAVQTPVNNQ
                     ANLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTASIKEEAQE
                     QARKEYEQQLEELLNRTNQSTAESSMENSKESDPSKAKEGSSDSTVHSNTSESSESNE
                     VK"
     gene            14976..17588
                     /locus_tag="ACG8ZV_001663"
     CDS             14976..17588
                     /locus_tag="ACG8ZV_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirD4-like conjugal transfer protein, CD1115
                     family"
                     /protein_id="HFS4997006.1"
                     /translation="MRIRETTRRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     QKIFYSGLAYLPLNYVVTRIPEAFHRFEIIPGSLQGVNIFQLQEMPQLFHFDSTGFWN
                     PLTPTTSLGTRLVVSTICVVPAVLMGLKMDMWFRPLADGQKGDNRLKTLKEIQQIYPQ
                     IPESKGSFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     RQSSMVVNDPKTELYVASKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYYPDPENEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNI
                     LSTAITGLNPFTLTKIAKMTSQSTIDYKSIGFPKYLDLKLHESLLNQRIVVEFYHKGK
                     KFHEERVKVGYRGFCEINFDCHLEQGDHVCLKYNHQGKQYVAWYEFSQKVLKDEEGKI
                     VYRKKRGETHLPELEKEAVLTLDEKKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHI
                     IVSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNML
                     WDLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENS
                     TINSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNH
                     GETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDEYARNLYHGL
                     HDQLEEKNEENMFYKIVQSFENETAKKLLIQFYEEQATDRLQEYVEKLIKNEEISEMI
                     RKRLLLEAEKAVKE"
     gene            17585..19963
                     /locus_tag="ACG8ZV_001664"
     CDS             17585..19963
                     /locus_tag="ACG8ZV_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pLS20_p028 family conjugation system
                     transmembrane protein"
                     /protein_id="HFS4997007.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDADPKTVTKVLQDYGNYLQYQDV
                     FSWICNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNELFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKVKNILVNLFMAMILIFGGSSLIDEGLNISKNFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PDQAKKMSESSDISTVQKDRLKALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYRRY
                     ISSPGIILAGESSLSVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSAIE
                     DISQSFLLLAFTILELRIYTLMLSGIGDLHAVGKINGFLYVVALIVLTIALFKGSQSV
                     TKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGFGH
                     RKDITHDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGTVE
                     DLTEKAKDTLEEKLDGTRAKEFAEAVKNPSEALEKQKEKASAVKEGLKDAYGEGQVNA
                     AVKANTTSEKENQEGAAIPSAKDHQDELHSNENSIGEKDSEEGQHGQLPKTDPEQYRY
                     KSNINSENEKRISDLPKRNQEVQTDEDSIDLPNDNGIEVGTEKSTKIGLPKTQNLPMK
                     DSRLNQFKENDQSFVHQSPAGTVQMKSSRLPENGNLTTVSYNLAESGETENASVQNIV
                     TKEAAPKPINKVHNGYRPANVAFTAPTKINVTRETKNRNNELKEQLLKDIKP"
     gene            20024..20566
                     /locus_tag="ACG8ZV_001665"
     CDS             20024..20566
                     /locus_tag="ACG8ZV_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997008.1"
                     /translation="MEDILIATFITALGAFLTIFVVTIKGFKDTDSLQKDHQSILDGQ
                     KTHTESIIVHLSEGFTYLKDAMPTFTVKLTEIFHSVEQISSELKEQRQQKDRQLGSLN
                     FRQETIQESLENVNRLNDEMQRVHLENEELRAQNYDLIQKKRNLEQKIVELKEENRQL
                     NYQLRRGKNRSRDLGNELEL"
     gene            20644..20976
                     /locus_tag="ACG8ZV_001666"
     CDS             20644..20976
                     /locus_tag="ACG8ZV_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997009.1"
                     /translation="MDKYIHMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKIVNNLV
                     HLPLFFALLNYGLWLAIALVIVWRPYNNPGQRQIFAIIESIFFTDKNHYHALDPNRNY
                     HGTYKEDE"
     gene            20977..21570
                     /locus_tag="ACG8ZV_001667"
     CDS             20977..21570
                     /locus_tag="ACG8ZV_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997010.1"
                     /translation="MRVKGQNSVDKKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLRKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            21592..23286
                     /locus_tag="ACG8ZV_001668"
     CDS             21592..23286
                     /locus_tag="ACG8ZV_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HFS4997011.1"
                     /translation="MLDVIKTAFSTQSNQKVIDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTDTQVTGKDPEAYPTFKEFLAFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNGATCSAVKSCGLQVV"
     gene            23974..25851
                     /gene="ltrA"
                     /locus_tag="ACG8ZV_001669"
     CDS             23974..25851
                     /gene="ltrA"
                     /locus_tag="ACG8ZV_001669"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFS4997012.1"
                     /translation="MTKETSPKDRKLRHAEYYGMTEIFDKIYSKSLKGDNFKNLMQII
                     ISDNNIVLAYRNIKRNHGSVTRGEDGVTIKDIENLNRNEFVEIVRKRFAHYNPRKVRR
                     VEIPKYNGKLRPLGIPSIWDRIAQQCILQVLEPICEAKFNNHSYGFRPNRSAEHAIAD
                     CMARMNQSHMEYVVDVDIKGFFDEVNHTKLMRQIWSMGIRDKQLLLIIRKMLRAPVVL
                     PNGKLIYPTKGTPQGGILSPLLANINLNEFDWWIANQWEEKDAKELKHHFRKNGAWDK
                     GNIYHKLRKSTTLKEIYLVRYADDFKIFCRNYNEAKKVFYATKMWLQERLKLPISEEK
                     SKITNLSKEESEFLGFTMKLVTKGNKKVVNTHIGTKAQSMIKVKLKKQIKRIQKSPNS
                     KDTFIYIGVYNSMVIGIHNYFKIATHCSVAMRKIARELRPSFEIRLREQGISKEGQYG
                     KYEGYKPYLRSGQIRYIRGFPILPVGYIQHRHPMCKKRNINKYTEEGREAIHKKQQTV
                     EEWKISWLCSNPVLSKRATIEFADNRISKFIAQKGRCAVTGEELILSEMHCHHIIPYH
                     ESKSDSYENLVIVTEEVHRVIHATQSETIEELLKYLKLNPKQKEKLNELRLKVGNEEI
                     S"
     gene            25982..26359
                     /locus_tag="ACG8ZV_001670"
                     /pseudo
     CDS             25982..26359
                     /locus_tag="ACG8ZV_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
     gene            26359..27558
                     /locus_tag="ACG8ZV_001671"
     CDS             26359..27558
                     /locus_tag="ACG8ZV_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFS4997013.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWVFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYKLL
                     PSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKFPN
                     SKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSAYYKNCMSII
                     NTNKLMEYDEFAIKHWREGGGTGGTITGSWGNPFPGSSLDKNSFSGGQLFGKNPGGEF
                     RPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVYQE
                     FANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDPLP
                     FLNSSKK"
     gene            27574..28218
                     /locus_tag="ACG8ZV_001672"
     CDS             27574..28218
                     /locus_tag="ACG8ZV_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997014.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQETNTYKIEEVAK
                     NASDKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPADDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVTDFSYFTR"
     gene            28229..29035
                     /locus_tag="ACG8ZV_001673"
     CDS             28229..29035
                     /locus_tag="ACG8ZV_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997015.1"
                     /translation="MSKKKGARQRFKKRKSYLRWLGIFMILGFLILASPIYTHKKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIKAKVIKVSDDYFVVKLAHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQMKDQEEIIQKLQEKIDRMTKEKI"
     gene            29057..29287
                     /locus_tag="ACG8ZV_001674"
     CDS             29057..29287
                     /locus_tag="ACG8ZV_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997016.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICREVNLSNTTISE
                     LKNGRKNLDTLKFRSFEALYVAAKKYFTADNK"
     gene            29801..30109
                     /locus_tag="ACG8ZV_001675"
     CDS             29801..30109
                     /locus_tag="ACG8ZV_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997017.1"
                     /translation="MEVRIRNVDEKIVREIDRRCDELSNRTGNKWSRNDYLKLLVEND
                     FDRPLMEYKQDKFDQLLNQLIDKFSFVQSHNTKVLEEYICQNNQIIELLIEQSRGGEV
                     "
     gene            30111..30533
                     /locus_tag="ACG8ZV_001676"
     CDS             30111..30533
                     /locus_tag="ACG8ZV_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997018.1"
                     /translation="MAKVIDKHIYFYETHIDVLDEIIATHAEVKNYSEAVRFLCMNYD
                     SEVEKKVNSNQAKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKANQTKKYSPKIKKTISESVTTKSEVFDPTRFLKR"
     gene            30553..32142
                     /gene="mobP2"
                     /locus_tag="ACG8ZV_001677"
     CDS             30553..32142
                     /gene="mobP2"
                     /locus_tag="ACG8ZV_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobP2 family relaxase"
                     /protein_id="HFS4997019.1"
                     /translation="MSKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEKERRTPEE
                     EQELRLIKNALEDFYIPEGETFSESKTGKEFSETSNEAQSLMKHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKVLTHSEQKEYQRLNQAIKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQTFQRGQQKGSIIYQDVVSHDHSYLEKIGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKKNTRKPYTEIENGVSYIVPKG
                     KRRQATLDEMKTNYVHELERFSYEKNRMGMEKRNLLTRKSDLRNTLTKVVKEPVRYDR
                     HAMSLLTEVYKNLPKKRSEWHYGDENRTKLSPYTREKLDELTQYVLTKEPGYQEYIQI
                     SKALKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKKQDSQIKPLIERMDQ
                     MQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEEK
                     YHASKAYEEQQRRIQMEQERQ"
     gene            32154..32489
                     /locus_tag="ACG8ZV_001678"
     CDS             32154..32489
                     /locus_tag="ACG8ZV_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997020.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLINEQF
                     DPNQFLVVEYPATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEMNEEGINNFPCKSI
                     EESISLTEC"
     gene            32630..>32817
                     /locus_tag="ACG8ZV_001679"
     CDS             32630..>32817
                     /locus_tag="ACG8ZV_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997021.1"
                     /translation="MAYSTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQSGDI
                     LTLNLTTKTFVDAAEDYP"
BASE COUNT        11900 a         5131 c         6702 g         9084 t
ORIGIN      
        1 ttagatggcg cgaccagttt tagaggcgat ggatatggat actttgacaa aaggaaggta
       61 tgtacagctg ttagctcgtg gttattcacc taaagatgta ttcaaatccc tgtctaaagg
      121 aacagatatg gaaaaagaaa gattacgaaa agaattcgat tattggagaa cccataatgg
      181 aatcaaggat ttgaaaccag cacggccagt aattaaacga aagaaaaaga taacccaaga
      241 ctgaagtgta gagcgtatgt gatcataggc ttttttattt ttgcaaaaaa caagaaaggt
      301 aggaaaactc atgaattatg aagaaatcga aaacagaaaa aaagtgtcga aagaaatgga
      361 agaaaagttg ctaaaaatga tgaaacaaaa acaccttaaa agattatctg tcatgcaata
      421 tatcaatgat atgaagataa caggaaaaga gaaagcttgt ttgttaggtt caatgaaaaa
      481 ctttgaacag ttgaggcgaa cttatgtaaa aacaggttcc aattgccaac tattattaga
      541 agtttcttga cgattatgat atgaaaatga tcaattatga tgtggcattg ttattgaata
      601 aaaagaatag taaaatttaa catggtttat cttggttaga tgtaggtaaa ttaattcata
      661 tatagaaggt agatagatga ataaaaacaa taaaacttta tttaatcctt acgtgggcgt
      721 aatcattgtt tttcttcttt ttagttattt tgcttatcaa ggttatcaaa aggacaaaat
      781 cgctgaaaaa gtagatggtg taacaaaaac aatccatatt caggaacagg ctaaaaccta
      841 tcaagataat ttaaccagtt taacggatat ttctaagaga caactgatta ctaatcaaaa
      901 acaggcatta gaaaaggatc tcaaaggtga aattgctgga aaacttgttt tttcttctac
      961 aggatttatt ctccctgttt ttcaaggagc gaatagcgac acgcttagtt taggagtagc
     1021 ttctacttat tatctagata ctgaaatggg aaatggaaat tatattcttg ctggttataa
     1081 cgtagataca ccaagcgttt tattatccga tatgactgat ttatctgaag gagaagaaat
     1141 tgatctaatc gatgctcatt acaagtatca gtatgaagtc tccaaaagag gaaaaatttc
     1201 tgattacagc caggtagttc aatctaagga aaacaattcc tttttatcct tgccaaaagc
     1261 aggtaaaaaa ccactactca cactgttagc ctttcaagca aataatatga aaaagtgcga
     1321 tgtgatccag tgtgaattag tcaatgtaga aaaaatcaat aaataaggga agtgagtcac
     1381 attcaagaac ttgtagaaaa attgatcaat aaaatgagtg ccatttttct gttactgttg
     1441 gtatccattc tatatttaat atggacggtg gggttaaatc ctcctacgat attatttatt
     1501 tatgataatg ctgcacagtt agtgacgttt ttcgtaggct gtttgtttct tttgaatctg
     1561 tacaaggtaa agagaaacga tctattcttc attgcagcag gcattctttt ttaccttttc
     1621 ttttcttttt ttagaagcta ccgaggagat actttctatg gtgatctgat cgttccgaca
     1681 attattgcta ttattttgat tgtaaaatgg acgaaattta ctgtaattga tcgtagcttg
     1741 tatcttgtag tattctatgt ctttttactc gtaacggttt atcgagtatt tactgagata
     1801 ccagtaccag aaggacaaag tatttggaat ccatcgaaca aattatcaga tatttggatc
     1861 aatacaaata cgataggtag ttctttaatg acattagccc ttcttatcac aggatttgct
     1921 agttcatttg gaaaatggta catgcgattg ctatcattac cagcgttgat tcttgctggg
     1981 gcaacgattt gggtttgcca atcgaaagca gcattatatg cgcttgttat cttcattatc
     2041 ttagaaattt tacctaagaa ggtttttcga aatacacact tgtccttttg gatgtatgca
     2101 gcagtttcgg ttctagcttt accgatttct tattttgctg caatgtcaga caaagttcac
     2161 ttatttacag gacgagaaga aatttggcgc aaattctatg aaacattagg cgaaaaaaca
     2221 ggacaaatat ttgtagggat gaaacctttc tttttccata gaggaaatca gattctaggt
     2281 aatcataata cgtatcacgc actcgtcaat cactatggat tgattggttt tgttctatcg
     2341 attattcttt tgcttagttt cttatggttg ctcgtaagaa aacgtgagct gacaaatgga
     2401 caactaacat tcttgtgggc ttttttagcg atcatgtgtc aatcgttcat ggaagaaaca
     2461 ttaacgacaa tcagttgggt gccaattgta ttcttaatgt tagcaatggc tacacaccaa
     2521 tataaaacca ccagataaat gaaatagaat agtaataaga gaaaacactt tttcgttgtg
     2581 aaaaagtgtt ttttgttttg tctgaaagga ggcagatgga tgaaaaaatg gttatttggt
     2641 tttttaggag tcgctttaat cgtcgtttgc agtgtgtttg gctatgttag ctaccaaaaa
     2701 catgaaggag aggtgtttaa gcaaaatata gaaaaaaaga tgcccgtaga tcaaatcaat
     2761 gcacacgcaa agagttataa ggaggatgca acgaacgtca ataatgatat gtctttgggg
     2821 caaatgttgt ccatacaaaa agaagcaatc gaaatgggcg tcaataaaca agtatttgca
     2881 caaattcaga ttcctgcact tggtttagca ttgccaattt ttaaaggggc aaatcaatac
     2941 actttgagtc ttggagcggc tacttatttt tatgaagatg ccgaaatggg taaaggaaac
     3001 tatgtcctag caggtcataa catggaaatg ccaggtgttt tattttctga tattcaaaag
     3061 ttgtcattag gggaggtgat ggacttagtt agtaacgatg gcgtctatcg ttacaaggta
     3121 acgcgtaaat ttatcgtacc tgagtacttt aaattaatcg atggcgttcc tgaagagaac
     3181 tctttcttgt ctttaccaaa gaaaggagag aaacccttat taacgttgtt tacttgtgtt
     3241 tatacgtcac aaggaaaaga aagatacgtg gtacagggag agctacaata acaagaattt
     3301 aatcaacgcg agtcgttgaa atatgaaatg aggagagtaa aaaatggcaa taaatcggta
     3361 tgtaaaaaaa gctggaatga ttgttggaat gttaggaatc attgcaggct gctttcaggg
     3421 gtatcgagct tatgcagaag atgtcacgca aaaaacgcca ccagaaaggg tcaatatcac
     3481 ggttcataaa ttaatgtacg atcaaagtac gcaattgaac gttgatattg acggaatcaa
     3541 aaatgatggt tatacgcacg atcaatatcc tacaggtgta acgaaataca acaaggcaga
     3601 ttatggtgat gttgagttta cgttaggaaa tattacggat caagtattac cgactgaaga
     3661 ttctgatcta accaacgcga aagtggacga aatcgttaaa gatgtagaag acaagggatc
     3721 taacagtgag tacgttaaga atgcaaccaa taaaattact tcagctgtag atgaaaatgg
     3781 tgagatcact tttgctgatc aaccagccta tgtcaattcc aaagggaatg tatatgtggt
     3841 ttatgaaagt aaatccgctg ctggattagt cacacaaaaa gcaaaaccaa tggttgtgat
     3901 tgcgccaatg acagacaaca caggatcagg atttttaaaa gatattcatt tgtatccaaa
     3961 gaacattgtt tctaagttga gttttgaatt aacgaaattt ggtgacgatg gcacagctca
     4021 aagcaaacaa acacctttaa aaggggcaaa atttgagtta tacaagggcg aacctggaaa
     4081 aggaacaaaa ttaggagagc ttgtatcgga tgatcaagga aagctgactg caactgattt
     4141 gacgttagga aaatactact ttgtggaagt tccttcagaa gttgtagttg gatcagatca
     4201 agaaccaaca gcagaccaat atttgttagg cgcagacgct cgcaacgatg cgcacaataa
     4261 gttaaccttt gaaattacga atgacggcgt gacaagtgat ttaaaagctt cctacgtgaa
     4321 ctataaagca ccagtgatcg ataaaacagt gacaaatgga acaggagaag aacattcttt
     4381 ccaaattggt gacgcagtga attatcaagg tacaattcat atccctacag atatcgcagg
     4441 tggaacagat gggattacag taaatggtgt aaaaagtgaa acttctcctt acagtgtatt
     4501 taaatggggc gacacagcag gtaaaggact ttcttatgtt gctgaaaaag cagatattaa
     4561 agtaacaaat aatgatggtt cagtcgtatt aaaagaaaat actgactata aaatcgaaaa
     4621 ttctgatagt ggttttgtga tcgattttat cgtaaataat ggacaagtaa gtgatacagt
     4681 tgcgaattta catggtcaag atctaaaaat gacttataac atgtttgtga atgatagtgc
     4741 tgaaatcgca aatccattaa caaatagcgt ggatttcgtt tataacaata atccatttaa
     4801 tcaggaagaa caccacgaaa aaacgaaagc tgacgttgtg acttatggcg caaaattctt
     4861 aaaagtcgat agcggcctat ttggaacagg tatcaaagca acaccgcttg aaggcgcaga
     4921 atttgcagct aagaatgcag aaggtaagta ctacggtgga cttactgata cagataaaga
     4981 tggtgtcaaa gaagcagttt gggtagacga tgtagcaaat gcagcaatcc taaaatcaga
     5041 taaagagggt cattttgaaa tcactggttt aactgaagga gattactcac tggaagaaac
     5101 aaaagctcct gaaaactatc aaaaattaac aaaagagatc tctttcaaag tagacaaaga
     5161 ttcatacaaa gaagaaaacc gaatcacgat caaaaataat caaaaagctt ccgtaccaat
     5221 gactggtagc aacggtttcc aatcttacgt attgatctct tgcttgttgc ttggggcagg
     5281 cgcaatttct gcagttgttt actttaagaa gaaagcctag aaggatcagc taatgattat
     5341 cagacaccct aagaaaaagc gaatcatggg taaatggatc attgctttct ggttactttc
     5401 agctgttggt gtcttacttt tgatgcctgc tgaagcgagc gtggcgaaat accaacaaaa
     5461 tcagcagatt gccgcaatcg atcgaacagg aacggcagca gaaacggatt cttctttgga
     5521 tgttgctaag attgagttag gcgatcctgt tggtattctt acaattccaa gtatttcttt
     5581 aaaactacca atttatgacg gaacttccga caaaatttta gagaatggtg tagggattac
     5641 ggaaggaact ggcgatatta caggaggaaa cggtaaaaat cctttaatcg cagggcacag
     5701 tggactttat aaagataatc ttttcgatga tttgccttca gttaaaaagg gagaaaagtt
     5761 ttatatcaaa gttgatggtg agcagcacgc ttatcaaatc gatcggattg aggaagtgca
     5821 aaaagacgaa ctacaaagaa actttgtcac ttacttagaa ccaaatccca atgaagatcg
     5881 agtaacgcta atgacatgta cgcctaaggg gatcaacaca caccgtttcc tagtgtatgg
     5941 gaagcgagta acctttacaa aatcagaatt aaaagatgaa gaaaataaga aacaaaaatt
     6001 atcttggaaa tggcttttag gaagtactgt ttttctttca gtcatgatca ttggttcgct
     6061 atttgtttat aaaaagaaaa aataaaggag ggtaaccaac atgagaaata gaaaatggct
     6121 atttgtttgt gcagccgctc ttttttcttt cactgcctac acacagttga cgtttgcaga
     6181 cagacaagaa agcacggata gcacagaaca aacaatccaa acgtcagata gcagcacgat
     6241 tcaaagcagc gatgaaaccg tcgattcgtc aacagttgat tcttcagaag aacctaaaat
     6301 tgctgaagac gatcaaatag tcaaacagac cattcacgtt caaaaaatta tttcttccga
     6361 acaattagac aaccaggggc aaaagcttga aaaacaagaa ggagtaaatg gcgcgaagtt
     6421 ttctgtttat gatgtatcgg acattttaca aaagatggat gttaaggatc tcactactga
     6481 ccaaattgaa tcccaattaa aagatcgagt gaaaaaacta tccagtgatc aactgaagct
     6541 aatttctaat ggagaaacaa agacaattga tcaacaaaca ggtgtctttg aattctcggt
     6601 agaagtacag gcaaatcaga aacaagctta ttatattgtc aatgaatcaa gtcctgaaaa
     6661 catttctaat agcgaggata ttttgctatt aacacctgtt tctgataaaa atggtgaatt
     6721 cttaaaggat gtgtggattt atcctaaatc agaagcttcg caacctaaag aagaagtaaa
     6781 aaaaatcgta tctactggcg taaagaaaaa cttctttgag aattgttggg attttgttac
     6841 tcacttgttt tctagagatt aaggaagaaa taaaatgaaa ctgatcaaat tattattatt
     6901 caatttttct tgtttaaccg cagtcttttt gtactgcggt ttattatttt ctaaactatc
     6961 tattttgcca agctaccaac tatacctaat gaggatttta aacataccag ctgcttccat
     7021 gccgctagat attatggaaa agctcattag gaatccatta tttactacga tcaatttgat
     7081 cgttattgtc ggaatttcac tagtcattta taaaaaagag gggatgaagg gatgaatttt
     7141 aaacactcgt ggacaagacg gttaaaatat gtttttccca taatgatgat gttaggtaca
     7201 ttgtttgggt taaaaacagc caatgtcttt gctgaaaaag ttattgtcga tccgtcaaat
     7261 ccaatccaga acgtaaagaa taattttatt attccaaaag atgttcctaa tgcaaaaaca
     7321 aatattactg taaacggagc gtcaaaagtt tacaaatatc atgttgatgc caacaaaggt
     7381 ggttttacag acgactacgt aggattagtg gagggaaaca aaaatatacg ctatccttct
     7441 ttccaaaaag aatacggtga aacaaacctt gttttagaag gcgtaacaac caacaccaaa
     7501 gtcaatattg actatggaaa aatcggtacg tataacggga aaaaagtcaa tatcaagcta
     7561 gttctatcta atattcactt atactcggat acgttgccgt ggaatctact agataacaac
     7621 tatacaaaaa ctcattttcg agacgatggc tataaaaata cgaatggtgc aatgagtaaa
     7681 tctaaaaaaa gaacagtact ttggatctca gacaatcttt tctcaggaat tgtttaccat
     7741 tcaacacaaa tgaatgtgca gctagtagcc acatatgagg acggtagccc cgttcaattt
     7801 tcaggagata catttatcag ttttaactct ttgaaccctg caggaggaaa aagcacggat
     7861 cttaaaggag aatatgccca ctatgacaaa atgaatacga cagattggta tgtcagaaaa
     7921 gatacggttc tttcagaatt taaatctttc tacaacaatc tgaacgtggt aggtggccac
     7981 ccaggaggaa gctctaagct gacacaagcg gataatgatt tcaataattt gcatgataaa
     8041 ttaggagatc cgaagtttgg tcaaggtact gtgtccttta aaatatctga agcaaatccg
     8101 acgtttgtga ttggttcttc taatgttcaa acctggttta ctttatcttc tgcgacaatc
     8161 tttagtgttg ttcctgatca acctgaaaaa acaggggttg ataaaaatgg aaataacgtg
     8221 aacgataaaa tgttgcaagt aggagacacg attcaatatc gaatcaaaca gaaggtgaat
     8281 cgattaggag tggatttact agcggtttac gatcgatttg agttaatcga taatttacca
     8341 aaagaagtaa attacgtcga tgcacacgtt gaaagtggta caaataaaaa attcgatgta
     8401 tctggtgaag tgacctatga caaaacaaaa caccaggtaa aatatgcagc gaaagctgat
     8461 acattaaaaa atcgaatgaa gtataacggc gaaacttacg aattagtgat caatgtaaaa
     8521 gtcaatgaat tggccaatca aaatagtgta gccaaaaatc agggaacgtc gatcattaat
     8581 aaagtagaaa aggatacaaa tatcattacc gtttatttcc ctaaaattcc agtgaaagaa
     8641 gtacaacaaa atggaaaaga tgtaaacgga cgaaatgacg gtaagaaggg tacgccgaca
     8701 gctcctttaa acgcaggatc tgaagtacaa tatctagtca cacaaaaatg gcacacaaaa
     8761 ggcgtagacg ctgcgtcaga tcactacaaa caatttagta ttcaagatcc aattgaagct
     8821 cgtttgacat ataaagaagg ttctgcgcaa gtaatagata agagtaaagg aaaagatatt
     8881 acttctgaag gcacactaac ctatgatagc aattcaagaa cgctgaagtg ggaagcttcc
     8941 gctgacttct taaataacaa tcttttagat ggacgagaaa ttcagctgat atttacagct
     9001 aaaactccat tacaatcaga aaaaaatatt gataaccaag ccgtagtagc agtagataat
     9061 gtttctaata aaacaaatgt tgtgacaatt ggggttgatc ctaacttgcc acaagttatt
     9121 gttcctaaaa caggttctac acatttagta acgattttag cggtcagctt actattactt
     9181 gtgttagcaa cttttggcta cgcagttctg aagttcaatt aaacaaaaaa acaaggctga
     9241 aaatcagcct tgtttttcta tttgaaaatg ggattggcac taataaatac gttgtctgaa
     9301 gaaagtgatc cgtctgcaga aacttcataa gcatgggata aaccaacgat actttgattg
     9361 ttgtaaagca agtttgcgtt atgagcagcg ctatctttcc acataaccat agcatttact
     9421 gctcctgtat ctgaaaggat ctcgtcaacg taaaggtaga aactattgat attttctcct
     9481 ttagcaccgt agcagcctaa gctttctaag agatcttgga aagtaccgcc gccaggtcgg
     9541 taatgactga agcttacttg taattctttt gcacgaatat ctgcagcttg ttgaacgata
     9601 tcattgaatt gcattggggc aacgccattt tgttgacggt agctatttaa ccaagcaagt
     9661 tctttttgac gcacatagtt gtttaaatca cttagtgaga tatttttgta tttgaaagtg
     9721 atcgttcgat tttggtcaac attattgatt acacgttgtc catttttatc aacggtaaca
     9781 gatgaatcgt catttctaca caagaagtag ttttgatcgg tcatattttt ccaagaagta
     9841 gagaaactat ctccctcgta aaccgtttgt gtttcagtag ataaaacagc gtttgtgtca
     9901 acgtttatat ggttcacagt gacgttgtat tgatgagtat aggcaaaatt gattccttga
     9961 ttacttgtaa cgttgtttaa agtcacagtg ttgctagagc tttctctagg atcaagaaca
    10021 aaattagtga acataggtgc ttcaattgtg atgctttgtc cataaacgac gggataactc
    10081 ttactgtaat tatagagttc ttggatattt ggatcagtat ccgagacttt atttggacga
    10141 gctttcactt caactagaaa gacttcatca tagtaaaaag taaatgtggt atttgtgtta
    10201 atcgtttgtg tttgtgtttc attcccattt acttgatact gtggtgcttc aaagttagtc
    10261 aagtcggttc tagcttttgc agtgtaactt gtaccagctt ttactgagac atgttcttct
    10321 tttagcagcg ttccagtttg tcgattcata tgacggacag ttaccgcata ttctgaaggt
    10381 ttaggtttgt gttgtaaccc tttaaatgca gaatcaagac tatttttagc attatttact
    10441 tgggtttgag aagctttaga atcgtctagt acttttttag cattggataa agcagtctga
    10501 aaattattcc aagatccttc tgtaaaatct cctttagcag ttgattttac ttggttgtac
    10561 aaggcttgta attccgtttt gttcacagta ggagctggtt ttttctttaa tcccttgtaa
    10621 gcagaatcta atgtgttttt ggcactatcc acttgttttt gagtcgcttt tgagtcattt
    10681 aacacttttt tagcattgtt taaagcggtt tggaatgcgt tccaggtatt gtcggtatag
    10741 tcaccttttt tagttccctt aacgctcgta taaagagctt ctaaagctga tttattcact
    10801 ttgggtttag aggtgtcagc accataccaa ccaatacctt cgtatttcca gccatagtct
    10861 ttggttaacc attgtacttc tttccaactt gcagtgtagt gatgcgaacc agaggtaaca
    10921 cctggaagga aaaggcggta gatcggttta ttattttttt cggcagaacg ccaggcaggc
    10981 ccttcataag tccaaccgta atttttggtc aaccatttca cttcatccca actagctgtg
    11041 taatggtgat cacgaaggcc tttattgtat aaacgataga caaggtggcc accgctagtc
    11101 ggtgcttccc aagcggggcc ttcataatta ccccacttaa ttttcactag gtgatcacgt
    11161 tcttttgtgc tagaggtgta aaaatgttca tggttatttg gattataaag gcgatacatg
    11221 acgttagttg aagcagcgtc agcagatcca gcaagagcaa ctgtggcagc aaatgttcca
    11281 atagctataa cagtttttgg gtttaataat ttcatgtttt caactcccta ttaaatgatt
    11341 aaatattttg tttacattca taatatacca cggtataccg aggtagtcaa cggtataccg
    11401 tggaaatttt gaaataaaaa agccgcccta tgaagagtgt aaggatggct gtttatatgc
    11461 tatgaagaaa tggattcggc gtatttggtt agtttggcag cattatcaaa tcgcattttt
    11521 tcaatcgcac tttttttctt tattaaatcc gcaattgttg attctgcgac tgaagaatgt
    11581 ttgctaattt catatgctgt cttgccagtt tcaaatagta accattcgat tttctcttta
    11641 tcagcgtaca ttgcaatgct ccctcttgat tttttcttta ttatagctct tttttgtaat
    11701 aaatcacaat atcaagagga aaagtttcta tagaaaggtg ggaaattatg agtatccgtt
    11761 ccccgtgtat caaaatgagg tttgttgcta ctttcgttat ttaatatact aaaataaaac
    11821 aacgaaagaa ggaatagaat gaaaaagtta ataatggtat ttacttcgtt gattgccatg
    11881 attgttattt taggtggatg tggtagtgaa aaaaataagc aagatagtca agataatggc
    11941 gtgttaaaac caggaacagt gtggaaagaa gaagtaggcg gacttgttca taatttaaaa
    12001 attatagatg atacaacatg ggaatattcc gaaagtgttt ggcatcctga acaagtacaa
    12061 ataacagttg agaagctaaa agactataaa ggattagaaa gatataaggt aatcgattca
    12121 ggtggagtag atttattcat aggtaaaaca gccttaatag ttccctataa caaagacggt
    12181 ttagaaacgt ttaaatttat tccaacaaac gaaaaagaac atcgagataa aagtgaaata
    12241 ttaaaagaat acagtactaa atctggatac aagttacaaa agactagcga gtgattgcta
    12301 gtctttttat ttatcctgaa ggaggaatcg cagtggcaaa agctaaaacg ccatttgaaa
    12361 aagccgcgtc taaaatctta gaacgtcgcg gtgtatctga aacacagtgg aaacaagaag
    12421 tccttgaaaa agcacaattt gacctattac ggggaaaaga caaggactta gaaggatata
    12481 tctatcaacg tgaacgtgaa aagcttgttt tcgatgaaat tattaaacac taaaaggagc
    12541 gaacaatttt atgtttgaat caattacaat gaatttttta acacaaccga aagtagtagc
    12601 tgcggttgat atttttagag cattacaagg tgcagcaact agtttaaaaa acaatctgat
    12661 gatttttgcg gctgtagctg ccgttgcctc cattgttctt ggggggattt tcttcttctt
    12721 tggccgaaga ggagctgaaa acgggaagat gcacgtaggt tatgtattga tgggggtagg
    12781 agttatatta gctgccgcct ctattgtggt ttcgttattt ggaatgtttg gacaaacccc
    12841 acagggacta taaaaaataa atagaaggag taaaaagtac gtggctactt tttactcctt
    12901 ttttatgaaa ggagaatact catgtacttt acgatttcag gcaataccaa aaaagataaa
    12961 gagttaataa aaaaagcaac gaagaaagtg ggaaagcgta ctgccttttt accgaaaaca
    13021 attaaatatt ctgtcattga aacggaagaa cagctacatg tgttaggaca agtgttagaa
    13081 caagagaatc aatcttctgt taaattgact ctcacgttac atgataaaga aggaaaaata
    13141 gaaaaggctg gcacagaata cgtttttggc ccactggatt atcaaatttc agaaggtttt
    13201 tatcctacat tgatggattt gatccgcctt gatgtgttta aggaaacgga tgaaaccatg
    13261 agtgtggaag agtcttatcg aaacgaaaaa ctgctacaag ttttagaaga agagttagag
    13321 agcgaccaaa gaaaagtgag tcaagtgagt gaagtcgaag taaatgatga agtaccatgg
    13381 gaacgaccaa tctttccaaa gaaggagtca aaagaaaaag agacagtcta tgttgacgaa
    13441 caagctgata ttccgactca gaaatcgata tttgaggaag agaacgatgt aatgggtcaa
    13501 ttggaggtag atccctttga agaaacaatg gaggatgaag agacggccga agtagaagtt
    13561 gatctagttg aagctaatga agagccaaca tggactgaag gggattctca ggaatatatt
    13621 gaaccactta tcagtgaaga agtagagaaa aacgaaacag agatacaaaa ggcaactgta
    13681 tttgattata ttttggatca atatccgcca gagcatgaat ggatgaaaga aaaaaataaa
    13741 ttatttttaa atgagcttta ttcgaaatat caattacccc aaacctatca agcattttta
    13801 gagagtaaag aagaattaat ctcacagggt aaaggcacac ttttagaaca gttagagtct
    13861 gttcaatcaa caaattggca tgagcttgca caagaagatt tattagccac ttttgaagaa
    13921 cgtcaacaag aaacagatca agaaataaat gagtatgcga cggaacagtc atctaattgg
    13981 gagagaacaa aagaggaact aaataaagaa gaacaacgag tgattgaaga agaagtacaa
    14041 aaaattaaag agcgatacga aaagaaacgc gacaatgcgt attccttgtg tatagagaaa
    14101 attaataact ttactaaaac taatcaagaa gctttatcga aagaaaaaga aaacttgtta
    14161 aaagaacgta taaaagaacg aaaagaagag ttctaccgag gtttacgtac agataagcta
    14221 aagattagca aagaattaaa tgaacaactg aataaacttt atcaaacaac gactgaagtt
    14281 cttatggaaa gacacgggca gatccagcaa gaattacaag cacaaattcc aaaatggaaa
    14341 aaagagtatg aaattcaaca acaagaattg aaagaacaag aagaaaaaca acgacaagaa
    14401 gaaaaagagc gcgaacaatt agaactaaaa aaacgtgagc agcatcttgc agaacaaaaa
    14461 gtggcgatag aaaaacaacg gttagagcaa gaaaaggaaa aagaagcagc tgctcgtaag
    14521 gaacgtcaag aacaaatgga tacattgcga caagcacagt tgaattatct agcacaacct
    14581 caaccagtag ctgctgttca aacgccagtg aacaaccaag caaatttaac tccttcacca
    14641 cagcgttcct ttaacggatg gatggtggga tgtattgcaa gtttaagctt gcttctaggt
    14701 ggaggaacag tatttgcttt taatcatatc aatcaatctt cacaggcaga ttctgtagcc
    14761 acaacggcgt caatcaagga agaagcccag gaacaagcaa gaaaagagta tgaacaacaa
    14821 ttggaagaat tattgaatcg taccaatcag tcaacagcag agtcaagtat ggaaaatagc
    14881 aaagagagtg atcctagtaa ggctaaagaa ggatcaagcg attcaactgt acactcaaac
    14941 acttccgaaa gttcagaatc aaatgaggtg aaataatgcg tattagagaa acaacgagac
    15001 gaaaagacaa acgattcaat ttagaaaaga ataggtatct ttctcatttc tatcgctata
    15061 ctccttcagg agaagagcta ccagaaaaac atgacaaacg tatttctcaa aagatttttt
    15121 atagtggctt agcttatctt cctttaaact atgttgttac aagaatacca gaagcatttc
    15181 atcgatttga gattattcca ggaagtttac aaggagtgaa tatttttcag ttacaagaaa
    15241 tgccgcagtt attccatttt gattcaactg gtttttggaa tcctttgacc ccaacaacaa
    15301 gtttaggcac acgtttagtt gtttctacga tttgtgttgt tccagctgta cttatgggat
    15361 tgaaaatgga catgtggttt cgtccgctag cagatgggca aaaaggagat aaccgattaa
    15421 aaacgttaaa ggaaatccaa caaatttatc cgcaaatacc agaatcaaag ggaagttttc
    15481 ctggttatgg cggaatacca attactcatt ataaaaaata ctggtatatt cagacggata
    15541 cagtaaatac ttgtattgtt ggtacttccc gctcagggaa aggccagata gaagttttag
    15601 caaccattga caatttgtcg cgtgcagaaa gacaaagttc aatggttgtt aatgatccaa
    15661 aaacagaatt atatgttgct agtaaagatg aactagaagc tagagggtat gatgtgtatg
    15721 cctttaatat caccgatcca ctgcaatcaa tgagtgataa tccattggca ctcattgtga
    15781 aatactggaa gcgaggagac atagacaccg caacacagtt aaccaatact tttacgaata
    15841 cgatttatta tgatgcaaat gcttcagaca ataaatactt taacgaaaat gcgcagaaag
    15901 ctgtcaatgc gcttattttt gcgttattgg aacaagcgga tcaaacaggg gattactcca
    15961 aattaacacc aaataatctc gttgaactac tttcagaaat tggcggtttt aattattatc
    16021 cagatcctga gaatgaattc aagcagctca atgccttaga tgagttcatg aatcagttac
    16081 cccctggaaa tatagcaaaa aaacaatatg gggcaacaaa aattggatct gataaagcga
    16141 aagggaatat cttgtctacg gcaattacag gattgaatcc atttacccta acgaaaattg
    16201 cgaagatgac ttctcaatcg accattgatt acaagtccat tggttttccg aagtatttgg
    16261 atctcaaatt acatgaaagc ctattaaatc aacgcattgt cgtggaattt tatcataagg
    16321 gaaagaaatt tcacgaggaa cgagtcaaag ttggctatcg tggtttttgt gaaatcaact
    16381 ttgattgtca tttagagcag ggagatcatg tttgcttaaa atacaatcat caaggaaaac
    16441 aatatgttgc ttggtatgag ttttctcaaa aagtattgaa agacgaagag ggaaaaatcg
    16501 tttatcgaaa aaaacgagga gaaactcatt tgccagaact agaaaaagaa gccgttctaa
    16561 cattagatga gaagaaaagt aacctattag tagagtctat tcggatgcac tataccgata
    16621 aaccaatggc tatttttatg ttaacgcctg attatgatcc atctaaccat atcattgtta
    16681 gcatctttct tagtcagttg tataaagaat tatctacgca atgtgttaag actaaaggag
    16741 ataaatgtca ccgtaggatt cattttattt tagatgaatt tggaaatatg ccaccgatgg
    16801 acaacatgga aggaatcatg acggttacgg caggtcgtaa tatgttatgg gatctgttta
    16861 ttcaatctta tcagcaactt tatgcgaagt atggagaaca aaacgcagcg attatcaaag
    16921 aaaattgtca gacacatatt tatattatgt cgacagatga taataccatc gaagaatttt
    16981 ctaaaaaagt ggggaataag acggttgaac aagagaacag taccatcaat tcattaggta
    17041 tgaatactca tatcaatcgc aatgttgatt cagatcgtat cttaactcct gaaagaattt
    17101 ctactttttt agaaggtgaa acgattgtac tcgctccttt aaaacgacaa gatttgaaag
    17161 gtcataaaat acggccgtat cctattttta atcatgggga aacgaatctt ccttatgctt
    17221 atcaatatat tgaagatttc aatccatcgt gggatatcaa tgatatagac atacattgta
    17281 cacatgcgga cttggatctt aaggctttac aaattgatta tgattatttc ctaccagatg
    17341 aatatgctag aaatctctat catggactgc atgatcaatt agaagaaaaa aacgaagaaa
    17401 atatgtttta taaaatcgtt caatcttttg agaatgagac ggctaaaaaa ttgttaattc
    17461 aattttacga agaacaagca acggatcgtc ttcaagaata tgttgaaaag ttgatcaaaa
    17521 atgaagaaat ttctgaaatg attaggaaac ggctgttatt ggaagctgaa aaggcggtga
    17581 aagaatgatc attggaggaa ttttctctgg catagccgac tggtggtcag gtttattcgg
    17641 agaaggggat gcagatccca aaaccgtaac gaaagtctta caagattatg gtaattatct
    17701 gcagtatcaa gatgtattca gttggatttg taatactttt ttatggggat tgatcaaagg
    17761 gttatataat ctcaatactt tattagaaaa aacaatttat caaagctttg atttaaaaga
    17821 cttattgaac gccgctggtg ttaatgaact atttcaaagt ttgattagta aggtattggc
    17881 tcttttttgt gtcgtcacat taatttattt aggcttgaaa ttttttatga gtaaacaccc
    17941 accgaaagtc aaaaatatct tggttaattt atttatggcc atgatcttga tttttggtgg
    18001 tagttcttta atcgatgaag ggttaaatat cagtaaaaac ttttatggag acgtcactgc
    18061 agcaaataaa gcagataaaa cgggttcacc tgcttttcaa attattcaaa ataatgtgat
    18121 tgatgtcagt acattactag cgactgaccc gaataaagta gaatccttac caacagataa
    18181 aagaaatgct ttaacagcga aaaatttcaa aacagcgaat atcaatggga ttattacacc
    18241 tgatcaagct aagaaaatgt ctgaatcaag tgatattagt acagtacaaa aagatcggtt
    18301 aaaggcatta cagtatcgac tagagttaga cgataatggg aaagaaatcc ctgttcaaat
    18361 tagtgatgaa ggtttagcaa aatatgtgta tacgtcaggc tatcgtcgat acattagtag
    18421 tccagggatt attttggctg gggaatcttc tttgtcggta gcctatttat ttattttgtt
    18481 tacaatcgtt acttgcatta ttgagctagt atttaaaaaa ttctatttag taattgccgc
    18541 gtcaacggac tttgagacag gacaacggat gaaaagtgcg atagaagata tttctcaatc
    18601 cttcttgtta ttggcgttta cgattttaga attacgaatc tatacattaa tgctttcagg
    18661 tatcggtgat ttgcatgcgg taggaaagat caatggattc ttgtatgttg ttgctttaat
    18721 tgtgctaact attgcgctat tcaaaggctc tcaatcggtt acgaagattt tcggtgttga
    18781 tacgagtctg aaaaacggca gcaattctct tcttagcatg tttgccttag gaaatattgc
    18841 gaaaaatgtg ggtagcggag ctaaaaacct tgcaagtgct ggtaagagtg gtttaagcca
    18901 tttaaatgat attcgtaaga atggatttgg ccatcgaaaa gatattaccc atgataacgg
    18961 ggaagaacaa tcagacgata aagctacaac tgtacctaat agtaagaaga cagtttccga
    19021 aatgttcggg aaagcgaaaa atggtgtttc taaagccgca gaaggtcttg gttacgtcaa
    19081 tgaacgtggg ttaaaaggaa cagttgaaga tcttacagaa aaagccaaag acaccttaga
    19141 agagaaatta gacggcacga gagctaaaga atttgctgaa gctgtgaaga atccatccga
    19201 agcactagaa aaacaaaaag aaaaagcttc agcagtcaaa gaaggactaa aagatgcgta
    19261 tggtgaagga caagtcaatg cagcagtgaa ggcaaataca acaagtgaaa aagaaaatca
    19321 agaaggtgca gcgattcctt cagccaaaga tcaccaagat gagttacatt ctaacgaaaa
    19381 ttcgatcgga gaaaaagatt cagaagaagg acaacatggt cagttaccaa aaaccgatcc
    19441 agaacaatat cgttataaat ctaacattaa ttctgaaaac gaaaaacgca tttcagattt
    19501 accaaaacga aatcaagaag tacaaacgga tgaggattcc atcgatctgc caaatgataa
    19561 tggcatcgaa gttggaactg aaaaatcaac gaaaattggt ttgcctaaga cacaaaattt
    19621 accaatgaaa gatagtcgtt tgaatcaatt caaagagaat gatcaaagct ttgttcatca
    19681 atcacctgca ggtactgttc aaatgaaatc aagtcgtttg cctgaaaatg gaaatctgac
    19741 aactgtttct tacaatttag ctgaaagtgg tgaaacagag aatgcgtccg ttcaaaatat
    19801 tgtgacaaaa gaagctgcac ctaagccaat caataaagtt cataatggat acagaccagc
    19861 aaacgtagca tttactgcac cgacaaaaat aaatgtgaca agagaaacta aaaacaggaa
    19921 caatgaattg aaagaacaac tattgaagga tatcaaacca taaaaggcct atttaagggc
    19981 ctttttcttt ataaaacaag tttaaaatgg aaaggagaaa attgtggagg atattttaat
    20041 agctacgttt ataactgcac tgggagcatt tttaacgata tttgtggtga ctattaaagg
    20101 atttaaagat acggatagtt tacaaaaaga tcatcagtct attttagatg gtcaaaaaac
    20161 acataccgaa agcattattg tacacctttc agaaggattc acttatttga aagatgctat
    20221 gcccacattc acagtaaaat taacggaaat atttcattct gttgagcaaa tatcgtcaga
    20281 attgaaagag caaagacaac aaaaagatcg tcaacttggc tcacttaatt ttaggcaaga
    20341 aacgatacaa gaatcattgg agaatgtaaa tcgattaaac gatgaaatgc aacgagttca
    20401 tttggaaaat gaagaattac gcgcacaaaa ttatgattta attcaaaaga aaagaaatct
    20461 ggaacaaaaa attgttgaat taaaagaaga aaatcgtcaa ttgaattatc aattacgacg
    20521 aggaaaaaat cgttctcgtg atttaggaaa tgaattagag ttgtaatatt tagaaaaacg
    20581 ctgtgagaaa tcacagtgtt ttttatttct aaaaatacaa aatataaggg gtatggttat
    20641 attatggata aatacattca tatgaaaaat cctccaagat ttagtgggga atggaagttt
    20701 ttcgcctttt tctttttaga tctattaacg cttggtggct gctttttttg ggcgaaaata
    20761 gtcaataatc ttgtccactt accactcttt tttgcactct tgaattatgg attatggctt
    20821 gcgatagcgt tagtgattgt ttggcgaccc tataataacc ctggtcaacg ccaaattttt
    20881 gcgattatcg aatctatttt ctttacggat aagaaccact atcatgcgtt agatcctaac
    20941 cgaaattatc atggtacgta taaggaggat gaataaatgc gagtcaaagg acaaaattca
    21001 gttgataaga aatccatttt gcagtttgga aaaccagaag agcgctctat cttggactta
    21061 tttccatata aatcctgtac agaagaggga gtcttaatta ctagagaaga tcattttcag
    21121 cgttattatc gtgtcgtttc cactgacgtg gagggattaa atgaacaaga gaaactagaa
    21181 cgaatgaatc agttgaccac cgtcatgcgt acgtatgtgc caacaattaa gttagttagt
    21241 ttgaccacag agacggatct aacggaacaa atcgtgcaaa agcggcagtt attagataaa
    21301 aatcgtatgg aacagtcact aggaagaaat ctacagcgat taagaaaata tgaaaagaaa
    21361 ttagtagagg agatccagga attaaaacgg gcagaacaag aacgtcctga cttaagcttc
    21421 tttttcgtta ttgaaggaaa gacaatcaag gatttacaaa ctagaaatcg tcagttaatg
    21481 cgatctagtg gcattttagg gttaaaacca ctctacaaaa aagaattgat taagattctt
    21541 tatcgaatga acaacatgaa tgacgaataa aaaagatgga ggaaatgatt catgctagat
    21601 gtgataaaaa cagctttttc aacgcaaagt aatcaaaagg tgattgatcc attaaaacaa
    21661 cttggtaatc gtgaaataga gattttaaaa tcaaaaggtt atgatttaga tttcttaaaa
    21721 caagtgatgc cacaaggtgg gttgaatttt gatgaagaat atgtgaccta tggaaatggt
    21781 tattcacgat gtgtgacagt ttatcattac acaaaaaatc ctactctttt ttggttggcc
    21841 aatctcatga acaatcctca tacagtggcc acactagatg ttagcacaga tgaaaagcaa
    21901 aaagtgattg atcaaatcaa ccgcgcatta gatgaattaa atgatcgatc agataatgaa
    21961 cgaaaagcga ctgaccgaaa taaaagtgcg gaagaatacc tggaactagc ggaatatgcc
    22021 cgaaaattga cttctaatgg ggaaatttct aaacaagtca aagtgagagt acatgtttac
    22081 ggaaatacga tccaagaagt ggatgaacgg gcgcaggaac tgatcgaaaa tctaaaaggg
    22141 atggattatc gtgcggtgac ttatctgcat aaaaccaaac gagattggca atcgatgttt
    22201 accatgttcg atgaacaagc tgaatggttt ggaaatatca aagggcaatc acttccatcg
    22261 ttaaacattg gcggaggatt cccgttccac caccaaacgc taaaagatcc aggaggcaca
    22321 caatatgggg aaaccatgac aggcggccca tttgtctgga atgccacgta taaaaatagt
    22381 gtacgtttat ctaccaatac cttgcttcta ggaatgatgg gagctggtaa atcgaccgtt
    22441 cttaaaatga tcgcggaagc ccatttagct gcaggagact ttatttgggg ctttgaaaag
    22501 ggaaaagact ttattccttt cttaaaggaa tataacggta ttatggtgcg tttagacgga
    22561 tctgacggga tgatcaatcc tttagagatc tttgccacac ggacgtatga tgaagcatcc
    22621 agtttatatg acgatggttc agtcaaagat ttgaagatca atgaagcagc gtcctatcaa
    22681 acgcacttag acaaagtagt ctatcaggta cagttagtga gtcctcagct aaaaggaacg
    22741 atgaaagcag aattcaagac ctacttgaat cgtttttatg aagagtatgg aacagtacca
    22801 cgcggtttta cttcctcaaa ttcgcgttca aatactgata cgcaagtcac agggaaagat
    22861 ccagaagctt atccgacgtt caaagaattt ttagcctttt taggacaact ggaactacca
    22921 ggggcttccc aagagaaaaa gaatcggaaa gaagaaatgg agtctatcgt ggaatcctta
    22981 tgtgagactt atggcatgat ttttgatggt catagtacga ttcgacacct tgaccaacaa
    23041 cagttggtct tttttgacat tgactctatt acaggcctag atcgaggggt acaacaatgt
    23101 cagatgtaca tggccatgac gttgatttgg aatcaggcat tgattcaagg acgaagacaa
    23161 cgacgcttaa ttaaagaaaa acaaatggaa gaacaagact tcaaacgctt cttggcgatg
    23221 attgatgagt gccataatgg tgcgacctgt tctgcagtga aaagctgtgg gttgcaagta
    23281 gtctaaaaac tattgtaata actcttataa cgagaagtca aatgagtggg taacgccaca
    23341 aagggcttcc actgatactc cgacatgcaa caagtagttt atgcagacca acgttgtgtg
    23401 aagctcggtg aagtcggctg aaggataccg taaggtaaaa gaaatagtga ataccacgaa
    23461 agttctctag aggtaaaggg tgtatccgat aagtcgggtg tccaaaaaaa cttaatatgg
    23521 tgagtatgta caaacgtact gacgaactag cgaatgtact gtccgaaagg catagctcct
    23581 agaaatggga gagacagtga gcaaaaaatc actcattgtg ctaacttgtg gttgagtaaa
    23641 agtcgttgtt atgaaagacc atgctgcgtt acaggcgtag gagaagttag ggggcaaaag
    23701 ctagcatcta agttaaggca tgtggataga tataagggaa caggggaagc catcaacatg
    23761 gagagtgcat actcgatgaa gtggtagtaa gaaatatgtg aatgacaaat aacttacttt
    23821 agtgatggtg aaagtagagt cacgactgat gaaggttctg taatggaact ggaggaacag
    23881 gctcgattcg tctgtaaaag tcatgaaacc cgttcaacca tgggattctc gtatgactaa
    23941 aaaggtcacg agccaattgg agcgtgataa accatgacaa aagaaacaag tccaaaagat
    24001 aggaagttgc ggcatgcaga atattatggc atgacggaaa tcttcgataa gatatactcc
    24061 aaaagtttga agggagataa tttcaagaat ctaatgcaga ttatcatttc tgataacaac
    24121 attgtcctag catatcgtaa tatcaagaga aatcacggta gtgtgacaag aggagaagat
    24181 ggagtaacga ttaaagatat tgaaaatctc aaccgtaatg aattcgtaga aattgttagg
    24241 aagcgattcg cacattataa ccctcggaaa gtaaggcgtg tagaaattcc taaatataat
    24301 ggtaaattaa gaccgttggg tattccatca atatgggata gaatcgcgca gcaatgcatc
    24361 ttacaagtat tagaaccaat atgtgaagca aaattcaata atcacagcta tggtttccgc
    24421 ccaaatagat cagcagaaca cgcaatagca gattgtatgg cccgaatgaa tcaaagtcac
    24481 atggaatatg tggtagatgt agatatcaaa ggtttcttcg acgaagtcaa tcatactaaa
    24541 ctcatgagac aaatctggtc tatgggtata cgagacaaac agcttctctt aatcattagg
    24601 aaaatgttaa gagcacccgt agtacttcca aatgggaagt tgatataccc aacaaaagga
    24661 acaccacaag gcggaatact tagcccatta cttgcgaaca tcaatctcaa cgaatttgac
    24721 tggtggatag caaatcagtg ggaggaaaaa gatgccaaag agctaaaaca tcattttagg
    24781 aaaaatggag cttgggataa aggtaatatc tatcacaagc tcagaaagag tacaactcta
    24841 aaagaaatat acctagtgag atacgcagat gattttaaaa ttttctgtag aaattataat
    24901 gaagcgaaaa aagttttcta tgcaactaaa atgtggttac aggagcgtct aaagttacca
    24961 atatctgaag aaaagtcaaa aatcacaaat ctttcaaaag aagaaagtga atttttaggc
    25021 tttacgatga aattagtgac caaaggtaac aaaaaggttg ttaatacgca tataggtaca
    25081 aaagcacaaa gcatgattaa agtgaaacta aaaaaacaaa tcaaacgaat tcaaaaaagt
    25141 cctaatagca aagatacctt tatctatatt ggagtctata acagtatggt tattgggatt
    25201 cataattact tcaaaattgc gactcattgt agtgtagcaa tgcgaaaaat tgcaagagaa
    25261 ctcagaccaa gttttgaaat acgactacga gaacaaggaa tctcaaaaga aggacaatac
    25321 ggaaagtacg aaggatacaa gccttaccta cggtcaggac aaatacgata tataagaggg
    25381 tttccaatat taccagtagg gtatattcaa cacagacatc cgatgtgtaa aaaaagaaat
    25441 attaataaat acaccgaaga aggtagggaa gccattcata agaagcaaca aaccgtagaa
    25501 gaatggaaga tatcgtggtt gtgtagcaat ccagtgctta gtaagagagc aacgattgaa
    25561 tttgcggaca atcgaatttc aaaattcatc gctcaaaagg gaagatgtgc agtaacaggt
    25621 gaggagctta tcttatctga aatgcattgt catcatatta tcccttatca tgaaagcaaa
    25681 agtgatagct atgaaaacct agtgattgtt actgaggagg ttcatcgggt aatacacgct
    25741 acacaaagtg aaacgattga ggaacttcta aaatatctaa aattaaatcc aaaacaaaaa
    25801 gaaaaactca atgagttgag attaaaagtt ggtaacgaag aaatatctta ataaatattt
    25861 gtaggacggg aaaacagaat gtcttttata gacgagggaa cgccgtatgc ggtgaaagtc
    25921 gcacgtacgg tgtggactgg gggaaaagac ggagataata tcaaactctt acctatcagt
    25981 atcgattaat ccagatttca ttgaaacggt aaattatgtc acaaacttcc aacgagaaat
    26041 gcgtaaagta gaagcaatga ctgttttagc tacacaatcc ccacaagaaa tggtgccaga
    26101 aaatatgtct tctgataact tctcgaaact gaagaaagtc tttgaatttt cttctacgaa
    26161 gatctttatg cgtatggatg aatctatttt acgtcatata gaaggattag ttggtaaatc
    26221 aatgacgaac tcagaattag aatccattcc tcaacaaaat caaggagacg ctgtgatcaa
    26281 ttttggctca aaagaaacca ttcgtgttca ttttagtccg aacaaacgtc aattaaaatt
    26341 gtttgatgga ggaaaataat ggaaaaccaa aatgaaagtt taatcaaaca gtatgttaag
    26401 cgtcgtgcaa agcggcgctt atttttgtgg gtgtttggta cttctgcagg tttgattact
    26461 atattgatca ctgtgtttgt gacccttttt ctaatacttg cggcaggttc tattgataat
    26521 tctgattcaa gtagtggtgg cgaagctttt acaggagaat attcggaagg cttacccatt
    26581 tataaagaaa tcaaaggaag aggccctttt tctgatgaga ttgcgcaata tgctgtaggt
    26641 gcagcagtga agtataaatt attaccaagt gtgatccttt cgcaatacgg ttatgaatca
    26701 gcgtttggta cgtcggcgtc cgcaagaaat gatctcaatt attttgggat tacgtggttt
    26761 gatgggtgtc tgtttcctaa aggaactgcg cgtggaattg gtggcattga aggtggctgg
    26821 tacatgaagt ttcccaactc aaaagctgcc ttctcctatt acggctttat ggtagccaca
    26881 caatcaaatt ttaatgcttg tgtcggaaat aaaagccctg gcgcaagctt attgatctta
    26941 ggacgaggag ggtatgccgc cgcaggaatt actgaagaca gtgcctatta taaaaattgt
    27001 atgtctatta ttaatacaaa taaattgatg gagtacgatg agtttgcgat taaacactgg
    27061 agagaaggcg gcggaactgg tggtacgatt acaggaagct ggggcaatcc attcccagga
    27121 agtagcttag ataaaaattc gttcagtgga ggacaacttt ttgggaaaaa tccaggagga
    27181 gaattccgac ctaacgggtt ccatgatgga ctagactttg gttcagtcga tcatccagga
    27241 agtgagattc atgcggttca tggcggaaaa gtcgtgtacg ttggcaatcc tggtatttca
    27301 ggtttgggtg cgtgtgtgat cgtgattaat tacgatggct tgaatatggt gtatcaagaa
    27361 tttgcaaata gtacaggaaa ttctcgagtg aaagtaggcg atcaagtgaa agttggtcaa
    27421 gtaattggga tacgagatac agcacacttg catttaggat ttactcgaat ggattggcgt
    27481 caagcacaag gacatgcatt cattgatgat ggtacatgga tcgatccgtt accatttttg
    27541 aatagcagca aaaaatagat caggagaaaa aatatggaaa ataaaacctt aaaaatcgtc
    27601 ttaacagctg caattagcgt tagtttaatc ggcaatattg cgttgttttg gcagcttaaa
    27661 gaagaacaag agacaaatac ctataaaatt gaagaagtgg ctaaaaacgc gtctgataag
    27721 ctcaaaaaaa attcttctga agcacaggcg aagattgaca agttaaatca aaccatcaat
    27781 gagaaaaacc aagaaatcga tcagctgaag caacaagatg gcacaaaagc aaaagaggaa
    27841 gtaactgaag cacaaagaaa gacggcagaa gagttcggtc aattggccat tgataaatca
    27901 ttaagcagaa atgaattaac ggaaaaacta aaagatgtcg caacccaaga agtgatcgac
    27961 aaattaagtc ctgcagacga tgatcaccaa catgacgact acggaagtta ctcttttaca
    28021 ttaggtgacg tgcaaactta cgctcaaaca agcagtgtaa aagaggaaca aaattttgtc
    28081 gtatttgttg attatacaat cggcaatcct caatttaaag atgtcaaacc acaaaaaata
    28141 aaaggtggat taactgtcac tgaaaaacaa gtagatggtc aatggaaagt cacagacttt
    28201 agttatttca ctcgttagga ggaagaaaat gagtaagaaa aaaggagcaa gacaacgttt
    28261 taaaaaacga aaaagttatc ttagatggct ggggatcttt atgattctcg gctttttgat
    28321 tcttgctagt ccgatttaca cacataaaaa ggtagacata ccagatgaag taagcacgaa
    28381 cgcattttta aacacgaagg aactgacgat ggtttcaaaa gaaaaaggag cgaaccagca
    28441 attagttttt gaatttgcga tcgacgatga agatcagagc ttattaaaag aactagctaa
    28501 tcttaattat cgtgtagaag taaagacagc taaaggggat tatcaagcaa taaaagccaa
    28561 agtgatcaag gtgtctgatg attattttgt agtgaagtta gcacatgtac cagaagaata
    28621 tatcgccatg cgtttaacca ttattcctga aaaaattgat ccaaaagtgg atatgcaaga
    28681 accacaagat ctgatttatt acgttcacga agataaggtt aaagatcaag tgaaagatga
    28741 agattatgaa caacatgcga tcaattacaa agtgaaagga tacaaaaaag aacaaaaagc
    28801 agcacaaaaa caaatggaat ccttccaagc aaccattgat ttgaatgaag aattagtgaa
    28861 gaagctaaaa gatcaattgc cttatcaagt cgcagatgat caggaaaata ctgaaaacaa
    28921 gattaatagc taccagcaag aaattgaaac atcgaaaacg caaatgaaag atcaagaaga
    28981 gatcattcaa aaacttcaag aaaaaattga tcgtatgaca aaagaaaaga tttagaagga
    29041 caggtggagt gaaaaaatga agcgaacaaa cttggctgac aaagatactt tcgctgagca
    29101 gaaagtattg attaaagcct atctcaaagt tgtaaaagct aaagaaatat gtcgagaagt
    29161 gaatttatct aatacaacaa tatctgagtt gaagaatggt cgaaagaatt tagatacttt
    29221 aaaattcaga tcatttgaag ctctatatgt agctgctaaa aaatatttta cagctgataa
    29281 caaataaaaa acaggagtat tttatgtgaa aaaagtatat aaaaaatgct tatgaatcag
    29341 ctatatcacc ttaaccattt gttaatgaga tgggagaaaa cattaaccac gattctaacg
    29401 caaacatcaa gcacataaaa catttaacac tcctcctttc tggctgaaga tttcaaccaa
    29461 acaggaagac agcgtatcaa ttatagcata cactttttct taaattcatt tttcatatga
    29521 caaaatattt ccttctaatc gacaaagtta gaaggatttt ttattgtcta aatacacaaa
    29581 taaccttaat ttataaagag cataaggaaa cgtgggaaca ctttttaaaa aaagtgttcc
    29641 aataggctgt gcctattacg tttctcaaaa ataattgtgg gaacaaaata tttaaaaata
    29701 ggatagtgaa aggatagcaa aggatagtaa aaggatagaa gcaggatagc gaaaaggata
    29761 ggctcctttt cgctatcctt tttaaattgg aggaattaat atggaagtaa gaataagaaa
    29821 tgtagatgag aaaatcgtaa gagaaattga tcgaagatgt gacgaactaa gtaaccgaac
    29881 gggtaataaa tggagtcgta acgattattt aaagctactc gttgaaaatg attttgatcg
    29941 tcctttgatg gaatataaac aagataaatt tgatcaatta ttaaatcagt taatagataa
    30001 attttctttt gttcaaagtc ataatacaaa agtattagaa gaatatattt gtcagaataa
    30061 tcaaattatc gaacttttaa ttgaacaaag tagaggagga gaagtttaac atggccaaag
    30121 ttatagacaa gcatatttat ttttatgaaa cacatataga tgttctagat gaaattattg
    30181 caactcatgc agaggttaaa aactatagtg aagccgttcg gtttctatgt atgaattatg
    30241 attcagaagt ggagaaaaaa gtaaattcca atcaagcaaa gttgaatgca atgggaaaag
    30301 aaatttctat tttaaccgaa atggtttcag agtttgcgga tctccatttg aaagatacag
    30361 ggattttaat tggtacaaat tcaactgttt accaagaagc aaaagagcgt gtggaaggca
    30421 agataaaagc aaatcaaacg aagaaatatt ctcctaagat aaagaaaaca ataagcgaat
    30481 cagtgactac aaaaagtgaa gtatttgatc caacaaggtt cttaaaacga taaaaattag
    30541 aaggagaatg tgatgagtaa atcacctgca gtcattctca cttgtcaatt taccttgccc
    30601 aataaaaaat ctttttcaac atacattgat tatatgacaa gagaaaaagc gctggaagaa
    30661 aaggaacgac gtacgcccga ggaagaacag gaactgcgtc taatcaagaa tgctttagag
    30721 gatttttata ttcctgaagg agaaactttt tcggagagta agacgggtaa agaattcagc
    30781 gaaacgtcga atgaagcgca atcgttgatg aaacatggaa tcaattttga caagttagaa
    30841 gaacaagatt ttaccaaata tctttcttat atgacacgtc actatgcgtt agaacaaaag
    30901 aaagtactga cgcatagtga acaaaaagaa taccaacgct tgaaccaagc aataaaaaaa
    30961 tatcaaacag agccacacaa aaaagcttca ggaaatcttc ctggagtttt ttctatggct
    31021 tcagacgaag tgaaaggaag tgatctgaag gagatcaagc aaaccttcca aagaggacaa
    31081 caaaaaggct caatcattta tcaagatgtt gtctctcatg atcattcgta tcttgaaaaa
    31141 ataggattgt acgatcccaa aacagatact ttagatgaag aaggtttaaa agcagctgga
    31201 agaaaaatga tggagacatt gttcgagaaa gagcaactga atgaaacagg ctactggatg
    31261 gcaacgattc accgaaatac caaacatatc catattcatt ttgcagttgt tgaaaaaaaa
    31321 aatacgcgta aaccatacac tgagattgaa aatggtgtga gttatatcgt accgaaaggg
    31381 aagagaaggc aagcaacatt agacgaaatg aagactaatt atgtacatga gttagaacgt
    31441 ttttcttatg aaaaaaatcg aatgggtatg gagaaacgaa atttattgac acggaaaagt
    31501 gatttgcgta acaccttaac caaagtagtg aaagagccag tacgttatga tcgacacgca
    31561 atgagcttat taactgaagt atataaaaac ttacctaaaa agcgttcgga atggcattac
    31621 ggggatgaaa atcgaaccaa actttcacca tacacaagag agaaactcga tgagttaacc
    31681 caatatgtgt taacaaaaga acctggatat caagaatata tacagatttc aaaagcattg
    31741 aaagaagaag caaaaagtct ttatggggaa agcaagagag aatcaaagga tgcagaaaaa
    31801 aatgctctct ttgatttaaa aaagcgcaca ggaaatgcca ttctaacaga actgaagaaa
    31861 caggatagtc aaataaaacc tttaatagaa aggatggatc agatgcaatc tatttacaat
    31921 gaacgatcct ttcgaacact taaacagttg ccaacgaatg aatacaaata tagttacgaa
    31981 gaattcatga agcgcaggaa acaattccaa caaagagttg tcacgcaacg gagtttgcgt
    32041 caattaaatc gaacgattaa tgcccatgaa gaaaaatacc acgcaagtaa agcatacgaa
    32101 gagcaacaac gaagaattca aatggaacaa gaaagacagt aggaggaata gcaatgaaac
    32161 aatatttaga tcaatggaaa gttatagaag gatcattaag agaagaacga atcgaacaac
    32221 ttcccgattg tttagaaaaa gagcatttgt ttcagataag agaaatgttg ataaacgaac
    32281 agtttgatcc aaatcaattt ttagtcgttg agtacccagc tactggtgtg tactgttgta
    32341 atcatgtgaa gggtgaaaaa tattttatca ttcaagaata tgagggcaag ttagcgcctt
    32401 attatactac ttgggaaatg aatgaagagg ggatcaataa cttcccgtgt aaaagcattg
    32461 aagagtctat ttcactcaca gaatgttagt tgttaagtga ataaaagaag taaaagagtc
    32521 ctgaacgtga ttgtccagga ctcttttttt tcactgaatt gttttccgcc aattcattga
    32581 gtggtgcgat ttccgtctac attatatcaa aagaaaggag gaagaagaaa tggcttattc
    32641 aacgattgga gttgttgttg aaaaaagcag agacaatctt gtttttgtga cagaaattca
    32701 aacaggcaga gcttttgtag tcacagacaa agcggcaaaa gcatatcaaa gtggcgatat
    32761 tttaacgtta aatctgacta cgaagacgtt cgtcgatgcg gcagaagatt atccatt
//
LOCUS       DAZULR010000031        32533 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.031, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000031 DAZULR010000000
VERSION     DAZULR010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32533
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.031"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            131..505
                     /locus_tag="ACG8ZV_001680"
     CDS             131..505
                     /locus_tag="ACG8ZV_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFS4997022.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="ACG8ZV_001681"
     CDS             complement(619..1248)
                     /locus_tag="ACG8ZV_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFS4997023.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="ACG8ZV_001682"
     tRNA            complement(1382..1454)
                     /locus_tag="ACG8ZV_001682"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
     gene            1668..1741
                     /locus_tag="ACG8ZV_001683"
     tRNA            1668..1741
                     /locus_tag="ACG8ZV_001683"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1702..1704,aa:Asn,seq:gtt)
     gene            complement(1879..2043)
                     /locus_tag="ACG8ZV_001684"
     CDS             complement(1879..2043)
                     /locus_tag="ACG8ZV_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997024.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2338..3666
                     /locus_tag="ACG8ZV_001685"
     CDS             2338..3666
                     /locus_tag="ACG8ZV_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HFS4997025.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3868..4701
                     /locus_tag="ACG8ZV_001686"
     CDS             3868..4701
                     /locus_tag="ACG8ZV_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HFS4997026.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4717..5454
                     /locus_tag="ACG8ZV_001687"
     CDS             4717..5454
                     /locus_tag="ACG8ZV_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="HFS4997027.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5609..6577)
                     /locus_tag="ACG8ZV_001688"
     CDS             complement(5609..6577)
                     /locus_tag="ACG8ZV_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HFS4997028.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6809..7642
                     /locus_tag="ACG8ZV_001689"
     CDS             6809..7642
                     /locus_tag="ACG8ZV_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HFS4997029.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7676..8515
                     /locus_tag="ACG8ZV_001690"
     CDS             7676..8515
                     /locus_tag="ACG8ZV_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFS4997030.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8541..9101
                     /locus_tag="ACG8ZV_001691"
     CDS             8541..9101
                     /locus_tag="ACG8ZV_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFS4997031.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9300..11021
                     /locus_tag="ACG8ZV_001692"
     CDS             9300..11021
                     /locus_tag="ACG8ZV_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HFS4997032.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11186..12328
                     /locus_tag="ACG8ZV_001693"
     CDS             11186..12328
                     /locus_tag="ACG8ZV_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HFS4997033.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12344..13555
                     /gene="thiI"
                     /locus_tag="ACG8ZV_001694"
     CDS             12344..13555
                     /gene="thiI"
                     /locus_tag="ACG8ZV_001694"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HFS4997034.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            14128..14775
                     /locus_tag="ACG8ZV_001695"
     CDS             14128..14775
                     /locus_tag="ACG8ZV_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HFS4997035.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    14904..15120
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15168..17813
                     /locus_tag="ACG8ZV_001696"
     CDS             15168..17813
                     /locus_tag="ACG8ZV_001696"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HFS4997036.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            18123..19436
                     /locus_tag="ACG8ZV_001697"
     CDS             18123..19436
                     /locus_tag="ACG8ZV_001697"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HFS4997037.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            19426..20079
                     /locus_tag="ACG8ZV_001698"
     CDS             19426..20079
                     /locus_tag="ACG8ZV_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFS4997038.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            20134..20826
                     /gene="radC"
                     /locus_tag="ACG8ZV_001699"
     CDS             20134..20826
                     /gene="radC"
                     /locus_tag="ACG8ZV_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HFS4997039.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            20976..21176
                     /locus_tag="ACG8ZV_001700"
     CDS             20976..21176
                     /locus_tag="ACG8ZV_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFS4997040.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(21430..23109)
                     /locus_tag="ACG8ZV_001701"
     CDS             complement(21430..23109)
                     /locus_tag="ACG8ZV_001701"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HFS4997041.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(23111..23323)
                     /locus_tag="ACG8ZV_001702"
     CDS             complement(23111..23323)
                     /locus_tag="ACG8ZV_001702"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit epsilon"
                     /protein_id="HFS4997042.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            23716..25446
                     /gene="efrA"
                     /locus_tag="ACG8ZV_001703"
     CDS             23716..25446
                     /gene="efrA"
                     /locus_tag="ACG8ZV_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HFS4997043.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            25443..27203
                     /gene="efrB"
                     /locus_tag="ACG8ZV_001704"
     CDS             25443..27203
                     /gene="efrB"
                     /locus_tag="ACG8ZV_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HFS4997044.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            27298..27495
                     /locus_tag="ACG8ZV_001705"
     CDS             27298..27495
                     /locus_tag="ACG8ZV_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997045.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            27648..28133
                     /locus_tag="ACG8ZV_001706"
     CDS             27648..28133
                     /locus_tag="ACG8ZV_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HFS4997046.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(28237..28830)
                     /gene="clpP"
                     /locus_tag="ACG8ZV_001707"
     CDS             complement(28237..28830)
                     /gene="clpP"
                     /locus_tag="ACG8ZV_001707"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HFS4997047.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            29010..29531
                     /locus_tag="ACG8ZV_001708"
     CDS             29010..29531
                     /locus_tag="ACG8ZV_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997048.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDV"
     gene            29628..30365
                     /locus_tag="ACG8ZV_001709"
     CDS             29628..30365
                     /locus_tag="ACG8ZV_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HFS4997049.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            30369..31286
                     /gene="miaA"
                     /locus_tag="ACG8ZV_001710"
     CDS             30369..31286
                     /gene="miaA"
                     /locus_tag="ACG8ZV_001710"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HFS4997050.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            31288..32517
                     /gene="hflX"
                     /locus_tag="ACG8ZV_001711"
     CDS             31288..32517
                     /gene="hflX"
                     /locus_tag="ACG8ZV_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HFS4997051.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEIAVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT        10772 a         5521 c         6874 g         9366 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt acttgattcc ggcatagctc
     1681 agttggtagt agcgcatgac tgttaatcat gatgtcgtag gttcgagtcc tactgccgga
     1741 gtaaataaag cttatgcaaa gaaaaagaaa tccaatcact tgggtttctt tttcttttat
     1801 tattatgatg aatcaagctt tctgtttttg tcacgtatgt tgtaatcttt acgaaagagt
     1861 agagttggct actcataatc aaccatactt cccatcatcg ctaaatacga aataaatcag
     1921 cattcctaca ccaatcaaag cacaagctgc accaagaaaa gggatgacat tcccaaagtt
     1981 atctgtattc ataagtatgc caccacccac aaacaaaaag ccgccagcaa tcaggttttt
     2041 cattttattc atctcctttc ttacgttata gtatttcctt ctttcaatga gtattttgaa
     2101 agctatctta ttgtatgatg ttcttctagg cctcttcttt attatacagg ccattttcgt
     2161 tatctcatag aaatattcct ttttatctga aaactattgt ataccgtatg acatttttct
     2221 tcatgaagtt gtaagtatat tctcattcaa atgaaaattt catcatagaa gagattgtat
     2281 ttctaaattc ttaagagtaa aatacgaagt ataacttgga tttggaagga tgattggatg
     2341 aaagctatta cgcctgatat gacaacaaaa tttaacaaac agtttcaagc aaatatcaaa
     2401 cagcaggcat tgcagcgggc agttgtgaag aacggaatta ctgcttctgc tgaaaatgtt
     2461 tcagcacatg tggagaatac accggtattt tctatagatt tggctacggg gaaagtggct
     2521 aatcaaatgc aatcggggcg ttgctggatg tttgctgcac tgaacacatt ccgtcataag
     2581 atgctgaatc aattccattt aaaagagttt gaattatcac aaaattacac ttttttctgg
     2641 gataaatatg aaaaggcaaa ttatttctat gaaaacatca ttgcaacagg aaaagaggca
     2701 atcgatagcc ggaaagtagc tttcttactc gctactcctc aacaagatgg cggccaatgg
     2761 gatatgatcg tttcattatt ccaaaaatat ggcgttgtgc ctaaatcggt gatgccggaa
     2821 agtgcgaata gttcaaattc tcgagatttg aataactact tgaacaaatt actgcgtaaa
     2881 gatgcagtag tgttacggaa aatggttgct caaggagaaa cattagacgc tattgaagaa
     2941 aagaaagaag aaatgctaga aagcatttat aacttcttag ctatctcatt aggaacacct
     3001 ccaaaagaat tcgattttga gtaccgcgat gaagaaaaga actatcatct tgaccgagga
     3061 ctgacaccac aaatttttta tgataaatac atcggtgtaa aattagatga ttatgttagc
     3121 gtgatcaatg caccaacaaa agacaaacca ttcaatcgtt cttatacagt agagatgcta
     3181 ggaaatgtcg ttggcgggaa agaagtcaaa tatctgaatg ttgatatgga aactttcaaa
     3241 aaattagcga ttgctcagct tgaagaagga gaatctgttt ggtttggttg tgatgtaggt
     3301 caatcttcta ctagaactag tggcatcatg gccttagatg cttattcaat ggatgatcta
     3361 tttgatacgg attttacaat gactaaagct gaacgtttag attttggaga aagtctgatg
     3421 acccatgcga tggtattgac cggtgttgac ttagtagacg ggcaatcaac aaaatggaaa
     3481 gtcgaaaata gctggggcga aaaagttgga aagaatggct tctttgttat gagtgatgcc
     3541 tggatggacg aatatacgta ccaaatcgtt gtaagaaaag atttattgac gaaagagcaa
     3601 ttaaatgcgt tcaatgaaga accaattgtt ctatctccgt gggatccaat gggtgcttta
     3661 gcatagacga gtatttcaat gaagagtatg tagtaaagat aaaaagagct ggcttaagcc
     3721 agctcttttt atctttaaag tccattccct gttttttatg gtccctgtgc tataattcta
     3781 aataaaggat aaggattgga aataatcctt ttatcattaa aaatatgatg acgaagtaga
     3841 ataaaattgg gagtaggggg gaaagtcatg gatatccaaa ctgttttatc tgatctgaaa
     3901 ttaaatggta aagtgattcc agttgttggt ggcgatgtta atcagaccta tcgtataaaa
     3961 accgaacatc gtgcttattt tttaaaaatc catccgaatg taaaaaaagg attttttgaa
     4021 gcagaagtag acggattaaa agaactgtca gcattcgtac gtgtaccgga tacgtatatg
     4081 ctaggtgaaa caagtgaagg cgcttatttg ttaatggaat ggatcgagcc gggaaaaggg
     4141 gatcaacgag atcttgctgc agctttagct aatctccatc agcaaacagc gccacaattt
     4201 ggttttcgta aagataacta tttgggtaca cttgttcaga aaaattcttt tgaagaagat
     4261 tggtggactt ttttctttaa agatcggctt gaatcccaga tttctttggc agaagaaacg
     4321 aatcgatgga atgtacagcg tcaagaaaag tatctgcgat ttaaagaacg tgtattgaaa
     4381 tcggttgaac caaaaaagat cactccacgc ctcttgcacg gagacctgtg gagtggtaat
     4441 gtgttctttg accagcaagg gcatccagtt tttgtcgacc cagctgtttc ttatgggaat
     4501 cgggaacaag atattgcaat gagccagtta ttcggtggtt tccgaccgga atttttagat
     4561 gcttatcaaa ctatatttcc attagaaaag ggatggaaag accgactgcc gatttaccag
     4621 ttatattatc ttttggcaca tttgaatatg tttggagaaa gttacggttc ccaagtagat
     4681 caattactag aaaattttta agaggagggc gtgtttttgg caaaaaaata taccaaaaag
     4741 catgaagttt catattatga gtgtgacatc aaccaaacga tgacatttcc ttcgatgtta
     4801 ggagtagtta tcaaaacgtc tgaagatcaa agcgaccagt tgggaagagg cagtgaattc
     4861 gtcaatagct ttggacttac ttgggtcatc acgaattatt ccatggagat taatcgtctc
     4921 cctagagtcg gtgaagtaat ctcagtaacg actcaagcca tggagtacaa taagtttttc
     4981 tgttatcgga acttctggat ccatgatgaa gatgggaaag aattagtcaa aatagaatct
     5041 gttttcgtat tgatggattt tgtgaatcga aaaatgagca gtgttaatga agagatcatt
     5101 gctccttttg agagtgagaa gatcaagaaa atcaagcgtc aggaaaaaat tgaaaagatt
     5161 gattcgggct tcatgttgcc atatcgtgtt cgtttttatg atatcgatag taatcagcat
     5221 gttaataatg cgatgtattt taattggatc attgacgtat taggatatga ctttttgact
     5281 acgcatgttc cagaaaaagt aattattcga tttgataaag aagtagagta cgggaatgag
     5341 atcgaaagcc attttgaaca aatccctatc gaaaatggtg tcaaaacaaa acatgaaatc
     5401 cgaatgcaag aacagctgta ttgtgaagca aatattatat ggaaaaataa ataaaaaaga
     5461 ggttgtgaca gaagggggca acttcaagaa ataagaagaa atttacgaaa attgtttctc
     5521 aaatttttgt aaattttcga cttagttttc gaagaagcta tttttgtcac agcctctctt
     5581 tttaagttta gctattagat aatgatgttt agttttggat aaacgaaatc aattcttcac
     5641 ccgacaaacc atagtttaca gcaatcaata gttttaaacg tgctttttga ctattaatac
     5701 tgttacagaa aataatcccc attttttcta gttcttttcc cccgccttca taatcataaa
     5761 caggctctgc gattccattg aaacaacgag aaacaagtac tacagggatt ttttggacaa
     5821 gaagcttttc caaagcagct aaggcttgtg gagggagatt ccccgcacct aaagcttcga
     5881 ttaccaaacc gtctactttc gtatgggcga tggcttccaa taagtcccct tgcatcccag
     5941 catatgcttt aacgatcggg atagtcccat ctacagcgga aatgtccagt cgctttgttt
     6001 ctaaaagttc ctgcaagaat aaaattcgat tcttagttac taagccgatg ggacccaatg
     6061 taggtgttcg gaaagtagca acatttgtgg tatgggtctt tgtcacgtag cgtgcagaat
     6121 ggatctcatc gttcatgacc accaaaaccc ccttatctag cgcttcttca caacttgcga
     6181 cacgaatcgc actttcaaaa ttataaaggc cgtcacttcc aagttcatta cttgaacgca
     6241 ttgccccagt caaaacaatt ggtaatttgt tgccaatcgt tgtatcaaga aaaaaagcag
     6301 tttcttctaa tgtatctgta ccgtgtgtga tcaccactcc ggatatacct gatgcataag
     6361 cggacaagat acgttctttt aataccaaca tgtgagaagg catgatgtgt ggtgagggaa
     6421 gattgaagat atcttcaact aataattcta catgcttggg gattgtgatt tctgcatcta
     6481 ataatgggtt tgccacatca ggactaacac cgcccgtgag catgttttct ttcatggcga
     6541 tcgttccgcc ggtgtgtagt acaagtattt ttttcatttt acagacttcc ttacgaataa
     6601 ttttgcatag ccgttaaatc ttattgtata ctatataaaa gagttttgct atcagtgaag
     6661 aataacgaat agcctaactt atcataaaaa agctgacctt attaaaatgg aaaagactca
     6721 accttgacct cctaatacaa tggagtatct ggttgagttt cttttacaag aaagcagcca
     6781 aggaaatcaa tcacgaaggt ggccggaaat gatcagaatc ggattaacat cgtttaaaga
     6841 acatgacaaa ttaactggta aaaagaataa cactctttat gaatatgcag ggtttctacc
     6901 cttagtggaa ttagatactg cctattatgg aattccccga aagtcctcag ttgagaattg
     6961 gataagtgaa gtacctgaat catttcgctt tgtagtcaaa gtctatcaag gaatcagcgg
     7021 tcaaggagac tggaagcctt attatcagac cgaagaagag atgattgcgc attttttaga
     7081 tgttatgtcg ccaatggtag atgctggaaa gatgttttgc tttttagtcc aattcccctc
     7141 atcattcaaa tgtacgaaag aaaatgtcca gtacttgcgc aaacttagaa agtggtttga
     7201 gggttatcct gtttctatag aattgcggga ttattcttgg tacagcgatg aatttcttga
     7261 acgtacaaga aactttatgt ctagagccgc tttttcttta gccatcatcg atgagccaca
     7321 gttgctgaat acaacgattc cttttgatcc atttgtcacc aatccgaact ttgctctttt
     7381 tcgattccat ggtaggaatg cgcaaggatg gcaagcaaat gataaagagt ggcgtaaaaa
     7441 aagaacgtta tatcgttatt cagaaaaaga actgcaagaa ctagcacatg aagtcaaagt
     7501 agttgattct aagacaaaag aggtaggtgt gatttttaat aataattctg gtggtgatgc
     7561 ggctgaaaat gcattagcac tgcaaaaaat attaaatatc aagccagatg gactcaatcc
     7621 aacccaaatg gatctgtttt aagggcttat tttattcaag aaaggggcga agtctatgat
     7681 caaagctatt ttttttgata ttgacggaac attggtcacc aatcgttcaa aagcgttgga
     7741 atcaacaaaa caagcaattg aatatgctcg gaaaaacggc attttatgcg gtgtagcaac
     7801 ggggcgcagc ccagtaaaga tcaaagaaat cattgatgaa ttggaattag atatgtatgt
     7861 cgtgtataat ggtcaactgg tttttactgc agatcgcacg attatcgacc acccttttga
     7921 acaaaaagta ttggaacata ttgttgaatt tgcagatgag aaccatcgac aaatcgtttt
     7981 tggtgcgaga aatcggttag atggatcaac gacgatgcta ttaggacaat cgatttttat
     8041 caagcgacta gtcagctttt taccgcgtaa attcccggta cgtctgatga aaaaaatcct
     8101 ccaggttttt agccctcacc gacaaaagga tcgttatgaa acgttagaga tattaaaaga
     8161 accaatttat caatgtatat tgctcagtcc ggagtcagaa cagaaaaagt tagaacatcg
     8221 ctttcccgag tgtacgtttc agcgttcaaa tacgtatact gtagatatca tcccaaaagg
     8281 tggttcaaaa ttactaggca tccaagcttt cgcaaatgct gtcgaaattg aaatggaaga
     8341 aattatggca ttcggcgatc attacaatga tatcgagatg ctgaaaggtg taggaattgg
     8401 agtggccatg gggaatgctc agatcgaagt aaaacatgct gcagactttg tgactcaatc
     8461 aaatgaagaa gatgggatat acgaaggact gaaacacttc ggtctgattt attagtcaat
     8521 gaaagaagga aaaaatcagt atggaagcag agacaccttt tcaaaaagta gaaacattcc
     8581 acaaaacttt tgatccaaga agaccagaga tacccacggc ttttacagaa aatgaagctc
     8641 atacacgtgc tgcgttcaaa atagaagaac ttgttgaatt tgttgcagct acttcaccta
     8701 ataaagaaca actgcatgaa gctgttatgc tgctgcacga agcattagat aaagcagaag
     8761 aaaaaatact tggtaaaaca cagtggggaa gtgatccgct ggttgaacaa gtagatgcac
     8821 tgacagatat cctttacttt acttatggtt ctttttcatt actaggaata gtgcctgatc
     8881 gaatattcga aatcgtccat caggcaaata tggggaaatt atttccagat ggaaaacctc
     8941 attatgaccc tgtaacaaat aaagtgttga aacctgaaaa ctggcagatg gaatatgctc
     9001 cagaacctaa aatcgcggca gaaatccaac gtcagattca agaagcgatt gctaagaaga
     9061 aatccgctga tataggcatg tgcacaaatg aaaaagagtg atcagagttt cactattttt
     9121 gttatcttta tacgatggaa aaacaaaaga ttttcgttta agttagtgaa tgcatgaaaa
     9181 tagtatgcta taatctagaa tagatgtctt ttgcacgaga gacgtattat ttggatttat
     9241 gccaagcaga acgccatctg ttgcataaaa gatgcatact gaaaacggag gaaccataaa
     9301 tgggaaataa tgttatcatc ggaatcgtca ttgcaatcat tatagtcgcc attgtcgtct
     9361 ttttggttag ttacttgatg aagaaaaaaa accaagatcg attggatgcc ttagaaaaac
     9421 gcaaggaaga attatttgac ttgccagtga ttgaagaagt cgatgatgtt aaaaaaatgc
     9481 atctggttgg gcaaagccaa aatacctttc gtgaatggag tcaaaaatgg aatgacatat
     9541 ctacttcctc gttcgctgaa ctagaaagtc aaattttcga agtggaaaac ctcaatgaaa
     9601 gttttcggtt cttaaaagga aaaaaagcag ttgttgaagc agaagctaca atggaccaaa
     9661 tggagaaaca agtgacggaa atccgtgaag gtctaaagga attgcgggaa acggaagaac
     9721 gcaactcact agctgttcag caggcacttg acgtctatga agaactgaaa gaaaaagtca
     9781 gagaagacga gcatgaatac ggaccagctc tttttgaatt gcaaaaacag atcaaagtga
     9841 tcgaaaaaga atttacgcag tttgtgactt taaacacttc tggagaccct gttgaagccc
     9901 gcgaggtttt ggataaagca gaaaaacata cgtatgaagt ggaagctctg atgaaaaaaa
     9961 ttccaccgct gtatgaggag ctccatacca ctttccctga acaacttgaa gaaatcagtg
    10021 atacttacga gaaattgatg gaagaacaat atgtattccc agaagaagat cttgctgaag
    10081 atatcgcaaa agtaagtcga agaattgaaa attcattagc caatcttgaa aaaacagaag
    10141 ttgaaacggt cgaatttgaa aaccgtgaaa cagctgattt gattgattcg ttatatgata
    10201 tcttagaacg ggaaatggaa gctcagagat atgtaaaaac taaccaatca acgattgcag
    10261 agtatatcaa acatacaaca aagaataacc gtcaattatt gattgagctg gatcacacat
    10321 ctcaaagcta tacattgaac cacaatgaaa ttggccgtgt acgaggtttc caaaccgaag
    10381 tggaagaaat ggaacgtcaa aatgaacaga tgattccaca gatccgtcaa cacgaaattc
    10441 cttattcaga agtgcgcacg ttctataaaa cagtcttcaa agtcttagaa gatatcgaaa
    10501 agcaacaagt agagatcgac gactcattac atgaattgag aaaaggcgaa aaagaagcgc
    10561 aagaaaagat cgatacattc gaattcaaat tgcgcagttt gaaacgtttt gtagaaaaac
    10621 aacgtttgcc tggcttgccg aatgattacc tagaattctt ttttgttgct actgaccgta
    10681 ttgaagaact aagtgttgtc ttgaataaaa ttcgagtaaa catggaagag gtcaatcgtt
    10741 tagttgctct atgtgaagaa gatctagaat tattagataa gaagacacat gatttagtag
    10801 atgcagcagc attaacggag caaatgctcc aatatgcaaa tcgttatcgt catacacacg
    10861 aagaagtgag agaagcaatt gataaaagct actatttatt caataaagaa tatcactatc
    10921 aagaagcatt agacgaaatc ggtacagcat tagagcgagt agaacctggt gctttcaaac
    10981 gcatcgaaga tttttatttt aatcatccag acttagtata aagcaaaaaa gttagtaaac
    11041 cagcaagagc aagacggatt attgtcttgt tcttgtcttt ttttgtatat ttgaaaattg
    11101 aaacaagtga aaatttcacc tgctcttgaa agcaccttgg acaaccgtta taatagaaaa
    11161 gaatttcaaa aaagaggggt ttcttatgat atattttgat aacagtgcaa caaccccaat
    11221 ctttccgcaa agcttagatg catatgtaaa aaccagtcag cggattattg ggaatccatc
    11281 aagcttgcat gatttaggca atcaagctaa ccggttgttg cagcaagcaa gaaagcagat
    11341 cgctgatttg atccatgtag aaccagaaga aatctatttt acttcaggcg gaacagaagg
    11401 agataactgg gtattaaaag gaacgatgat cgaaaaaaga gaatatggga atcatatgat
    11461 catttcagga gtcgaacatc cggccgtcag cgagacagca gaacaattaa aagaattagg
    11521 aatcgaagta agtatcgccc cagtggataa acgcggattt gtacgtgtcg acgaattgaa
    11581 agaattaata agaaaagaga cagtattagt ctctgttatg gctgtgaata atgaagtagg
    11641 atcgattcag cccatccagg aaatcagtga tcttttggat gattttccta aaattcattt
    11701 ccatgtagat gctgttcagg cgattggaaa agtaccattc tcgcaatggt tgacagaaag
    11761 agttgatttt gcaacatttt cagctcataa attccatggc ccacggggaa ctggtttcat
    11821 ttattggaaa aagggtcgtc gtttagcacc attactgaca ggtggagggc aagaaagaaa
    11881 tcagcgaagt gggacagaaa atgttccagg tattgtggct atggttaaag ctttacgttt
    11941 atcattagag ataaaggaac aaaaacctga gcagacacaa cgcttaaaag tagctctaat
    12001 caatgcgttg aagacgtatg agaaagtgac gattttttca gaaggaactg actatgcacc
    12061 gcatatttta tgttttgctc taaaaggaat tcgcggcgaa gttctcgtcc atgccttaga
    12121 agaaaaacaa atatttgttt ctactactag tgcctgctcc tcacgtaaac atatggcaag
    12181 cagtacattg cacgcaatgc atgtaccaaa tgatctggct acatctgctg ttcgaatcag
    12241 cttagatgaa aacaattcgc ttgcagaagt cgagcaattt atgattattt tcaagcagct
    12301 ttataagaaa ttttctgcaa tcaattaaaa gaggagtgtt cttgtgaaat acagtgaaat
    12361 tatggtccgt tatggggaac tttcgacaaa aggaaagaat cgaaaaagct ttatcatgca
    12421 actagcacaa aatgtcagac aagctttgaa agactttcca gaaatcaaaa tccatgctga
    12481 tcgggaccgg atgcatcttt tattgaatgg cgcagacggg cagctagtta ttccaaaact
    12541 agcaaaaata tttgggatcc aaaatttctc tccaagtatt cgtgtagaaa aagatgtcga
    12601 agttttgaaa caagctgttc aagacatcat gaaagaaatt tatactggga aagaaacatt
    12661 taaaattatc gctaaaagaa gcgatcacca atttgaattg acaagtaatg aattgaatca
    12721 aacattaggt aatgctgttt ttgatatttt cccgcatatc caagttcaaa tgcgtcaacc
    12781 agatattcca ttacgtgtag agattcggcg tgatggcgct tatctatcgt atgaaacgat
    12841 caagggagct ggaggattgc ccgtaggaac aagcggaaaa ggaatgctta tgctttctgg
    12901 ggggattgat tctcctgtag cagggtactt tgccatgaag cggggagtgg aaattgaagc
    12961 tgttcatttt gctagtccgc cgtatacaag tgaacaagca ctgcaaaaag caaaagatct
    13021 aacagccaaa ctagcacctt atgtgggaac gatccatttt atcgaagtgc catttaccga
    13081 gattcaagaa gaaatcaaaa agtcagtgcc acaaggatat tggatgacaa ttactcgtcg
    13141 aatgatgttg cgtttgaccg atgaaattcg ccgtattcgt catggtttag tcattttgaa
    13201 tggtgaatca ttaggtcaag tggcttcaca aactttgcaa agtatggtgg ctatcaatga
    13261 agtaacgaat acgccaatca ttcggcctgt agcgacaatg gataaacttg aaatcattga
    13321 agtagcagaa cagatcgata catttaatct ttctatccag ccttttgaag attgctgtac
    13381 gatttttgct cctccacagc caaaaacacg ccctcaactg gaaaaggtcc atcaatatga
    13441 agagcgttta gcaatagatg aaatgatcca acgagcacta gctggcttga agatggaaga
    13501 gatacaagca gaatcgtcta atgaaaaaac tgaagaattt tcagaattgc tataagaggt
    13561 tatgaaaata gtgttttgac cagagtatta gagaaacaaa acgaaaaaat agctccatgt
    13621 attttaccgt ttttgaacta atgtcgaaga ttagctgatt gaataccatt tatcaagaag
    13681 ttatggaaaa gccggttctt ttttactaac tgaaaaataa aattttattt agagatcaag
    13741 ctacagttga taaatgatat aaaaaagaga atttcccatg aaatagcgag gttgtgacag
    13801 aagtgggcag cttcaagaaa taagaaggaa tttacgaaaa ttgcttttca aatttttgtg
    13861 aaatttcggc ttatttttcg aagaagttac ttctggaaca ccgtgtatca gaggttgcga
    13921 aaaagctgcc ctgcatcaag taataagaac agccaaacaa aaatagttcc tcatatttta
    13981 cgtttggttg agcttattac cgcagatgca agcttttgaa caccgtttta tttgtctcac
    14041 acccttttcc ttcctacttg taaccttgct cccgtgttag aaacatgtta cactaaatat
    14101 gtgaaattat taacaaggag cgtcgttatg cgagaaaaaa cagatacact gccaaaagca
    14161 actgcgaaaa gattaccttt atatttacgc tacttgaaga tgctggatga ctcaggtata
    14221 agtagaatca aatcaaatga gttcagcgaa atcacccaaa ttccttctgc aacgatccgc
    14281 agagacttct cgcaattagg cgagctaggc agaagcggat atggctatga tgtccctttt
    14341 cttatcgatg tattcaataa tatccttaat actaaagaag aaaaacgaat cgcattagta
    14401 ggatatggaa atcttggcaa agcattgaaa cacaacaatt ttagaagaaa tgaaaatcta
    14461 aatatcgtgt gcgtctttga taatgatcca gcactgatca atcgagtaat tgatggagaa
    14521 atgatctatc cgattgatcg tttcgcggag atagccaaag caaaaaatgt gacagtagca
    14581 atctctacgg taccaagtaa atattcacaa tctgctattg atgaaattgt caaaggaaat
    14641 gtaaccgcta tacttaattt tgcgcctgac agagtaactg tcccagctta tgtcaatgtt
    14701 caatacattg atttgacaac cgagttgcag acgcttattt actttgatga gaattactca
    14761 gaagtttttt cttaggaaaa tttgagtagg cttattgatc ttgcgagaac tcgtcgtaat
    14821 tctttcaaaa attttttagt actaaatgaa gtggtttttt cacgaccact tgttgactaa
    14881 aaaaaaaaac cattgtagaa tgaagcataa cgctgaacaa gaggagtaac tggcacattc
    14941 attcttagag agagaactat ctgctgaaag gttctcaatg acaaccagtg aaggtagctt
    15001 gggagtttct gtcttgaatg gagtagagat agacgagtcg tgatcgttaa ctcacttgag
    15061 aggcaataat gattgattat tgcaatttag gtggtaccgc gtaaatcata cgtcctagaa
    15121 tacgaaagta ttttaggacg ttttttagtt taaaggagga aaacagcatg acggaagaaa
    15181 ataacctatc aacaaaatat aatccgcaag aagttgaagc tggacgttat cagcattggt
    15241 tagaacaaga tttgtttaaa ccgagcggag ataaaaaagc aaaaccttat tcaatcgtaa
    15301 tcccgccccc aaatgttact ggaaaacttc atttagggca tgcttgggat acgaccttgc
    15361 aagatatgct gattcgtcaa aagagaatgc aaggatatga tactttatgg ctgcctggta
    15421 tggaccatgc aggaatcgcg acacaagcaa aagtagaagc gaagcttaga gagcaaggga
    15481 tttctcgtta tgatctaggt cgtgaaaagt tcatcgatca agtgtgggaa tggaaagaag
    15541 agtatgcgag ccacatccgc gaacagtggg ctaaaatggg cttatcttta gattacagta
    15601 gggaacgttt tacattagat gatggattat ctgaagcagt acgtaaagtt tttgttacct
    15661 tatacgaaaa aggtttgatt tatcgtggtg aatatatcat caactgggat cctcaagcac
    15721 gaacagctct atctgatatc gaagttattc ataaagatat cgaaggcgcc ttttatcata
    15781 tgagctatga actagcagat ggatcaggcg tagtagaaat tgcgacaacc cgtccagaaa
    15841 cgatgttggg agatacggcg attgctgttc atccagaaga cgagcgttat caagcgctca
    15901 tcggcaaaaa agtgattcta cctttagtca ataaacaaat cccaatcatt gcagatgaat
    15961 atgtagatat ggaattcggg acaggtgtag taaaaatcac tccagcacat gatccaaacg
    16021 actttgaggt aggtaatcgt catgatcttc cacgcgtaaa tgttatggat gatgatggta
    16081 cgatgaatga actagcagga aaatatgctg gaatggaacg ttttgctgct cgtaaagcaa
    16141 tcgtgcaaga tctgaaagaa atcggtcgat tgattaaaat cgatacgatg atccacagtg
    16201 tgggtcattc cgagcggaca ggtgtcgttg ttgaacctcg gctgtctact caatggtttg
    16261 taaaaatggc gccgttagcg aaaaaagcca ttgataacca agaaacagat caagcagtgg
    16321 aattcttccc tccaagattc aatcaaacgt ttttacgttg gatggaaaat gtccatgatt
    16381 gggtaatctc acgacaatta tggtggggac atcaaattcc tgcatggtat cacaaagaaa
    16441 caggtgaaat gtatgtaggg atggaagcac cagcggatag tgaaaactgg gtacaagatc
    16501 ctgatgtttt agacacttgg tttagttcag ctttgtggcc tttctcaaca atgggctggc
    16561 cagatacgga aagcgaagat tataagcgat acttccctac tagcacttta gtaaccggtt
    16621 atgacatcat tttcttctgg gtaagcagaa tgattttcca aagcttggaa tttactggcg
    16681 aacgtccatt tgagaatgtc ttgattcatg gattgattcg tgacgaacaa gggcggaaga
    16741 tgagtaaatc attaggtaat ggaatcgatc cgatggaagt aatcgaaaag tatggagcag
    16801 atgctctccg ctggttctta tcgaatggtt ctgcaccagg acaagatgtc cgcttcagct
    16861 atgaaaaaat ggatgcttct tggaacttta tcaacaaaat ctggaatgct tcacgtttcg
    16921 ttatcatgaa tatcgaagga atgaccgtag aagagatcga tttatctgga gaaaaatcag
    16981 tggctgaccg gtggatcctt actcgtttga atgaaacgat cgaacgagta actgagctat
    17041 ttgatcgttt tgaatttggt gaagcaggtc gacaactgta taactttatc tgggatgatt
    17101 tttgtgactg gtacatcgaa atgagtaaag aagtacttta tggagatgat gctgtttcaa
    17161 aacaaaccac ccgtagcatc ttagtccata cacttgatca gatcctacgt ttattgcatc
    17221 caatcatgcc attcgttaca gaagaaatat gggaacatat tcctcatcag ggaaattctc
    17281 tagtagtggc agaatatcct gttgtacgtc cagagtttga tgatgaaaca gcttctaaag
    17341 ggatggaagt attgaaagaa ttgattcgag ccgttcgaaa tattcgttca gaagtgaata
    17401 caccattgtc taaaccaatt acgttgctaa ttaaaacaaa cgatgctaaa atcgatcaat
    17461 ttttagttga aaatacaagc tatatcgaac gcttctgtaa tcccgaagag ttgacgatat
    17521 caagtgagat cactgcgcca gatctagcga tgtcagctgt tctgacaggt gcagaaatct
    17581 tcttgccgtt agcaggattg atcaatattg aagaagaaat caaacgatta gaaaaagaac
    17641 tggaaaagtg gacaagcgaa gtaaaacgtg tccaaggaaa actttctaat gaacgttttg
    17701 tttctaacgc gccggaagaa gtagtagagg cagagcgtgc aaaagaaaaa gattatttag
    17761 agaagcaaac ggctgtcaaa gaacgaatcg aaagtttgcg tactattcaa taagaataga
    17821 aaaagagagt gtgaaatcag ctagctatta ctaaaagcta gctgattgaa catcgttaca
    17881 ggaaagagtt tgagcctcac tcttagcttc gattcataag gagatgtgac ataaattttg
    17941 tcgcatctct tttttagtct actcttatta tgtaggagaa ggagggaggt ggatcatgta
    18001 tcaagagtca ataaagtagt tgataaaatc gttcctctct ctgtttcttt tctctttgtc
    18061 atacttttat ttttcttatg tgttctattt gttataataa aagagaaatg ggggaattgt
    18121 tgatgacgat tgaagaagca atagaatgga tccatagtcg attaccattt ggttcacgtc
    18181 ctggccttga ccgagtcgaa gctttattag aagtggtagg gcatccagag agaaaagtaa
    18241 aaacgatcca tatcgctgga acaaacggaa aaggttctac tgtagcttat ttgagaagcc
    18301 tattagaaga ggctgggctg acagtaggta catttacttc accttatatc gaaacgttca
    18361 atgaacggat cgcaatcaat ggcaaaagca ttccagacaa tgatttgatc cagcttgtaa
    18421 aaaaatatca gccactgatc aaacaacttg atcaatttga agcagtagct ggtattactg
    18481 aattcgagac attaacagca atggcatttg attatttttt gatgaagaaa gtggacgtag
    18541 cgattatcga agttggctta ggcggcttat tggattctac caatgtagct gtaccaatgc
    18601 tgacgggaat aacaacgatt ggacttgatc ataccgaaat acttggagat acaattgaag
    18661 aaatcgctgc acaaaaagct ggaatcatca aacaaggcgt tccagtagta acaggaaata
    18721 ttgccccaga agcttttact gtcatccaac aaacagctaa agcaaaaaat gcaccgcttt
    18781 atgtatacgg ggaaaattat aaaataaact atctgcatcc tgatgagatg tggggagaag
    18841 tatttgaatt ttttaatgaa ataggaaaga tccctcaatt aaccactccg cttttagggc
    18901 aacatcaagc tgaaaatgca ggagtagcca tcgaattgta ttttgtttac tgtcaattgg
    18961 aaaagctgcc tttccgagaa aaagatgttt tgaagggatt gaagaaatct cgatggccag
    19021 gaagaatgga gcgtttgagt aacgagccat tagttgtttt agatggtgcc cataatacgc
    19081 atgcaatgaa ccggcttgtt gagaatttga aaaaagaatt caaaggatat caaatcaaca
    19141 ttttgttttc cgccttacga actaaaaatg ttagagaaat gctagaacga ttgcagcaag
    19201 taccaaatgt ccatatttat ttgacgacct ttgaacatcc aaaagccatc gaattaagtg
    19261 aagtatcaga tttagcaagt gagagagtat caatcgtttc attgtggcaa ttcggattag
    19321 cagatatatt ggaaaagatg acaaatgaag acgtattagt tgtgaccggt tcactttatt
    19381 tcatttcaga agttcgccat ttattaatac aattaggagg agatcatgaa gtataatgca
    19441 gtgatttttg acatggatgg tttgctgttc gacacagagt tagtgtatta cgaagccaca
    19501 caagtagtag cagacaagat gggttttcct tatgataaag acctgtattt aaaattctta
    19561 ggtgtttcag atgaagaagt atgggcgaat tatcatatga ttttctcgga atttggcaaa
    19621 acaagtgtac aaagattcat agatgattca taccaggaaa cgcttgaacg tttttcgcaa
    19681 ggagcggtac aaatgaagcc cggtgtgttg gaactcctct cttttttaga agaacatcag
    19741 attcccaaag ttgtcgcttc cagtaaccaa cgagcagtca ttgaactttt attgaagaag
    19801 aacaatctgt ttgaacgatt tgagacgatt gtttctgcag aaaatgttca acgagcaaaa
    19861 ccagacccag aaattttctt gttagctaat cagaagctag gtacagcgaa gaaagaaaca
    19921 ttgattttag aagattcaca aaatggtatt ttagcagctt ctgcggctga gatcccggta
    19981 gtcatggtac cagatctgct tccaccatcc caagaattga tcaaaaaaac agctggggtt
    20041 gtttcttctt tacatgaaat ccctgcattg ttaaaataaa aatccatctc ttttcgtatc
    20101 ttattttaga taagatagaa aggagatgtt tttttgggaa aacgattgat caaagaagta
    20161 cctactagct ctttaccaag ggaacgtatg gaaatttatg gcgcggaagc tttatcggat
    20221 caggagcttt tggcaatctt actgcgtacc ggtcaacacc cttatagtgt gatgtcgatt
    20281 gctggaaatc tgttaaaaac gtttggagga ctggcctctt tacgacaggc tactttgcat
    20341 gagttagaag agattcgagg gataggacgc gtgaaagcaa tcgaaatcaa agccttgatc
    20401 gaattaggtc gacgaattca gacggatcat gaaagagcgg ctccaccggt tcgtaccagc
    20461 tacgaattgg cccagcaatt gattctggaa atgaaagatc acaaacaaga acatttggtt
    20521 tgtatttatt tggacacgaa gaatcaagtg atcttaaaaa aaacagtgtt catcggttcg
    20581 ctgaatcagt cagtcgctca tcctagagaa attttccatt atgctgtacg ttattgtgca
    20641 gcaaggatcg ttttagcgca taatcatcct tctggtaatg ttattccatc gcagcaggat
    20701 atgaatttta ccaaaaggat acaaaagtgt ggagaaatga tggggatcac tgtactggac
    20761 cacttgatca tcggacgcaa acgatatttt agtttgagag aagaaggaat gatggaagag
    20821 aagtaagttg ctttcttgca aaaaaaatga agcaagtgta caattatatt gtaattttgt
    20881 ttgggaatag aagttgaaac atctgttgca cctctatcgt acacgagcaa tgttacaatt
    20941 taaattagtg cttttggcac gaggaggata ttattatgga aaacggaaca gtaaaatggt
    21001 tcaacgctga aaaaggattt ggatttatct cacgtgaaga tggaagcgac gtattcgttc
    21061 acttctcagc tatccaaggt gacggattca aaacattaga agaaggtcaa gcagtgactt
    21121 tcgacgttga agaatcagac cgcggcccac aagctgcaaa cgttgtaaaa gcttaatttt
    21181 atctgtaaat caaattgatg gtagacatca atttttacga gagaacaaag cgagtaacaa
    21241 aaatacctgc cacaagagac aatttctctt gtggcaggta tttttttgta tgaaaaagta
    21301 aataaattta agaggctatg aaagagccac cttgtatcaa ggaataagaa caaacaaaaa
    21361 tggcttctca tgtttttcat ttgttttctc ttatattcag gacaaggtgc tgatttcata
    21421 acctcttatt tattcttcat ctggtgtcat taccattggc aaaatcattg gatgtctttc
    21481 tgtacgttcg aataagaaag gctgaagcgc gccagtcatc gcttctttca atttatattc
    21541 tgaacagtca ggtccattca aacattctct taaagcgtgg aataagattc gctgagcttc
    21601 attgatcatt tctcctgatt ctcgcatgta gacaaatcca cgagagagaa tatctggacc
    21661 agccaagatt tcttttttct tgatatccac tgtcgcgaca gctaatacaa gaccttcttc
    21721 tgaaagcagg tgacggtcac gtaaaacgac attaccaata tcaccgatcc cgctaccatc
    21781 gatatacaca tctccagcca caaaatgccc agcaggacgc gcagaatcgc tagttaacgc
    21841 taaaacatcg ccattttcca tgatgaagca gttttctgca ggaacaccta catcttgtgc
    21901 tagagaagca tgtactttca acatgcggaa ttctccgtgg acaggaataa aatattttgg
    21961 cttcatcaaa cgaagcatta atttttgttc ttcttgtcca ccgtgaccgg aagtatggat
    22021 gttattgatt tttccgtgaa tcacttctgc accagcttca gacagcaaat tgatcaaatg
    22081 attgacactt gttgtattac caggaatagg tgaacttgaa aagatcactg tatcgtctgg
    22141 ctggatttgg atttgacggt gagtaccatt cgcgatgcgg ctcaacgcgg ccatcgcttc
    22201 tccttgagaa cctgtacata ggatcatcgt ttcattggca ggcaagcgat tgatttcgtg
    22261 tgcatctaca aatgtgccgt ctggaacttt gatatatcct aaacgttgac cgttgacgat
    22321 ggcattttcc atgcttcgtc cgaaaacagc gattttacga ccagttgcca cagcggcatc
    22381 tgctgcttgc tgcaaacgga agatgttaga agcaaagctg gcaaaaatga tacgtccttc
    22441 gatttttgaa aagatcttca aaatagaatg cccaatcgtt ttttctgatt tagtaaatgt
    22501 tggaatctca gcatttgtac tatcagataa aaggcacaag actccttctt ccccgatacg
    22561 agccatttta tgcaagtttg ctggttcgcc aacaggagtg aaatcgaatt tgaagtctcc
    22621 agtcgctacg atatttccag aaggtgtttt caccacgatc cctaatgcat ctgggatact
    22681 atgggtcgtt ctgaaaaagc tgacagaagt ctttctaaaa cggatgatcg tatcttcatt
    22741 gatctcatgg agctctgcat ctcgaagcaa gccatgctca tctaatttgt ttgtgatcaa
    22801 cgctaatgcg agaggaccag catagatagg aatatttgct tgtttcagca agtagggtat
    22861 tccgccgatg tggtcttcgt gcccgtgagt aatcaccaag gcttttactt tgtgtaagtt
    22921 ttgtatgatg tagctgtagt cgggaatgac atagtcaatt ccaagtaaat cgtcttccgg
    22981 gaatttgatc ccggcatcaa tcaaaatgat ttcatcttgg aattgtaccc catacgtatt
    23041 tttcccgatt tcacctaatc caccaatagc aaagacgcct gtctcgttat ttttgatgga
    23101 aagtttcata ttaaaactcc actaatgaga aatcagcatt ttctttttcg tactctagat
    23161 gacttccttc tagaagttga acgaattcaa tattgtatgg ggtattttct tccacacgtt
    23221 ggcgagcgtc tacatcgctt tttgcctcaa tgtaaagaga ttttgtttct tcccgtttag
    23281 ggttgcgtac ttttgtttct tgataataaa ctttatagat cattgttttg tctcctttat
    23341 ctgcgtaaag cagtgattta gctagttgat ttttttagac aacacaaaac gaggggacaa
    23401 gccacctggt ttttcatatg ctttgactag aatactggat tcgagtcaaa gagacaagcc
    23461 tcgtttttgc ttatctgttc ggatattttt tcaaccgtac cttctgtata aaaaatatac
    23521 aacaattaat tgttattcta gcataaaaca gcaaataagt atagaaatca actagattga
    23581 aagaaaaaat caatgtttat catcccgcta taatcataat gactttttta tgagagaagt
    23641 gttctattaa taggctcgtt gtgctatcat ttttagtaat gaaaatgtaa caaaagatta
    23701 aaaggagatg agaaagtgaa actaatgtgg cattatacca tgcgttataa gaaattcttg
    23761 tttttcaatt tcatatgcgt atttggtttt attttgattg aattaggact tcctacgatt
    23821 ttagcacgta tgatcgatgt aggaatccgc aatgatgatt ttgattatgt gaagcaacaa
    23881 gggatattta tgatcgttat tactgtaatc ggtattattt tgaatatctt gttaggttat
    23941 tttggttcga ggattacgac taatatcgta gcagatattc gagatgattt gttcgaaaag
    24001 atccaaagtt attcgcatca ggaatacgaa aatctaggcg tatcttcatt gatcactcgt
    24061 acaacaaacg atgcttatca gatcatgttg ttcctgcaaa atattttacg tatcggtttt
    24121 atggcaccaa tgatgttcat tgtcagtttg tacatggtca tgcgtacaag tgtgacactc
    24181 agtttgtatg tagtaggtgc attaccttta ctattattgg cagtcgtagc gattgctaag
    24241 gtgtctgaac cgttatctaa aaagcaacaa aaaaacttag ataaaatcaa cagtatcttg
    24301 cgggaaaatc tttcaggatt gcgtgtgatt cgtgcattcg tcaatgaaaa gtttgaagaa
    24361 aaacgttttg ctgtagtcaa tgagaattat gcttctagtt caaaaagctt attccgtttg
    24421 atggctgttg cacaaccggg tttttatttc ttatttaata tcgtaatggt attgatcatc
    24481 tggagcgggg cagtgcaaat cgatgcaggc gagcttcgtg taggagattt gattgcgttt
    24541 atcgagtata tattccatgc cttgttctca ttcatgttat ttgctagtgt gttcatgatg
    24601 tatccaagag cagctgtttc agctggacgt atccaagaag ccctagatgc caaaccttcg
    24661 attgtagaag atccaaatgg tatatctgat acaaaaacta aagggtatat cgaatttcaa
    24721 aatgtaacat ttgcttatcc aggccattcg caagagccag tgatacgaaa tgtcagtttt
    24781 acagcctctc caggagagac cgttgctttt attggaagta ccggtagcgg aaaatctacg
    24841 ttgatccaat tgatccctcg cttttatgat gtgagtgaag gaaagatctt gatcgatgga
    24901 gtagacgtga gagattatcg gctaagcaag ttgcgagata agattgggtt tattccgcaa
    24961 aaagcgctgc tatttactgg aacgattgca gataatttgc gatacgggaa agaagatgct
    25021 acgcaagaag aaatggaacg tgcagctgag attgctcaag cttcagaatt catttctcga
    25081 aaaccagatg gatttaatga acatttatca gaaggtggtt ccaatttttc aggtggacaa
    25141 aaacaacgat tggcaatagc cagagccatc atacgccgtc cggaaatcta tatttttgat
    25201 gacagctttt ctgcattaga ttatcaaacg gatgcgaagt tacgtgctcg tctgaaaaaa
    25261 gaaacgacag aatctactgt attgatcgta gcacaacgtg tgggaacgat catgcatgca
    25321 gataagatca tcgtattaaa tgaaggagaa gtcgtcggta tggggacgca tcgggagttg
    25381 ttggaaaaat gcccgattta ttatgatatt gccgcttctc aattatcaaa ggaggaatta
    25441 gcatgaaaaa aaccttttct tccttaaaac gtttagctcg atatatcaga ccgtatcgtg
    25501 agacttttct tttagtgatc ctatttacag ttctgacagt ggctttcaac gtggctttgc
    25561 catatgttac aggacttcct actacagaaa tcagccgtaa tattgccaat ggcgaatcaa
    25621 tcaatttttc ttatatattc aaatgtctca tttggatcac agttgttgga atagggtatt
    25681 gtatttcgca attactttct ggtgttttga tgacaaatgt cgttcaaagt gccatgcatg
    25741 atttgagaag agacatagaa gaaaaaatca atcgtcttcc ggtttcatat ttcgataaaa
    25801 accagcaagg aaatattttg tctcgtgtga cgaatgatgt agatgcagtc agcggtgctt
    25861 tacaacaagc ttttattggt atcgtaaatg cgatattggg aattacgttg gctgcagcaa
    25921 tgatgtttta tatccagccg atgatggcgc tgatctctat gatcatgatt ccaacatcga
    25981 tctggatctc aaaacgagtg atcaatgctt cgcagaaata ttttcaaagc atgcagaatt
    26041 ctcttggtga gctaaacggc tacgtccaag aaaatatgac aggttttagt gtattgaaag
    26101 tatatggacg cgaaaaagaa acattggaag gattcaaaaa agttaatcac agcttgaaat
    26161 actttgggtt tcgtgcagca ttcatttctg gcttgatgat gcctctagtt caattaactg
    26221 cctatgctac ttatattggt atggctgttc taggaagctt ttatgttatt actggggcga
    26281 tcgttgtcgg tcaactacaa gcattcatcc aatatatttg gcaaatcagt cagccaatgg
    26341 ggaacgtgac acaattgtct tcagttttgc aaagtgcatc agcggcaacg aaacgtgtat
    26401 tcgagatttt agatgagcca gaagaaaaag aaaacaaagt agatgcttca ctgccagaaa
    26461 cgattttagg agatgtgaca ttcgatcatg tcgattttgc atatgatccg aagaaaccat
    26521 taatccaaga tttgaatttt gaagtgaaag ctggtcaaac cgtagctgtg gtcggtccga
    26581 ccggtgccgg caagacgaca ttgatcaatc tattgatgcg tttttatgac gtagacaaag
    26641 gagcaataag gattgatgga atcgacacca aatcaatgag tcgcagtgat gtgcgttcgc
    26701 tatttggtat ggtcttgcaa gatgcatggc tttatcaagg aacgattgca gataatatcc
    26761 gcttcggaaa gcttgatgcg acagattatg aagtagttga tgctgcgaaa acagcaaacg
    26821 tagatcattt tatccgaacg atgccagatg gatatgatat ggccatcaat tctgagggag
    26881 acaatgtgtc tttaggacaa aaacagttgc tgacgattgc ccgagcagtg gtctccgatc
    26941 ctaaaatctt gattttagat gaagcaacaa gttcagtaga cacccgttta gaagcgttga
    27001 ttcaaaaagc aatggatcgc gtgatggagg gacggacaag tttcgtcatc gctcaccgtt
    27061 tatcgacaat ccgtgatgca gatctgattc tagtgatgga tcaaggtcag atcattgaaa
    27121 aaggaacgca tgagagttta ttggcacaag gtggatttta tgaaaaactg tataacagcc
    27181 aatttgctga ggaagcagaa taagtcatat aagaataaaa cagtttaaaa cttatttttt
    27241 gttctctatt cttgataatg gtaaagtaaa gttatcaaga aaagtgagga cacggagatg
    27301 gaacagtttt taaatgaaaa aattactgaa gccaaaagag aagttgatcg tttaacgcac
    27361 gtctgtcaga cgaagccttt tgattcagct gatttttttg aaaatgagtt tcaaatcgaa
    27421 cgcttggcag cacaaataga agtgtacgaa ttaattttaa aaaaagtaat agaagaaaat
    27481 atagatgtac aataaaaaca ggtaaaacgt cagttaccag atactgtaaa tagacatctg
    27541 gcctgagcag gttttacctg ttttttttct tatgaaataa atatatgcta tgataccttt
    27601 attcaatagg attagtttct acaaaaaatg aaaggagaaa aataaatatg gaacggttta
    27661 tagcatcaaa tgccacagtg attggtgatg tgacattgtc agaagatgtg acgatctggt
    27721 atcaagctgt tttacgcggg gacagtaatt ggataaaaat aggacaaaga acgaatatcc
    27781 aagatggtac aatcatccat gtcgatcatg atgcacctgt agatattgcg gagaatgtga
    27841 cggtaggaca tcagtgcatg ctacatggct gtacaatcga aaaaggggcg ctgatcggga
    27901 tggggaccac gatattgaat catgcggtta ttggtgagaa tagtttgatt ggtgctggat
    27961 cattagtaac agaaggaaaa gttattcctc ctaatgtctt ggcttttggt cgcccagcta
    28021 aagtgatccg tcctttgaca aaagaagaaa tacaaaaaaa caaagaaaac atccagcatt
    28081 atgtcgagat aggtcggatg catgcgcaag gaaaattcaa ggagcaaaga taggcagtag
    28141 catccataaa ataaaaaagg atggtcagtt tgagttgacc atcctttttt atttggttta
    28201 gataagagag cttaaaaaag cttcctttga aacagattaa tttaatgaag aactgttttc
    28261 catgacttca tcgatcaatc catatgcttt tgcttgttca gctgtcatat agttgtcacg
    28321 atctgtatct ttttcaatca cttcaagcgg ttgtccagtg cgttcagcta aaattttgtt
    28381 taagcgttcg cgtgtttgca aaatatggcg tgccgcaatt tcgatttcag ttgcttgccc
    28441 ttgagcgccg ccaagaggtt gatggatcat gatctcagca tttggtaaag caaatcgttt
    28501 accttttgta ccagctgtca gcaagaagct tcccattgaa gcagccatac ccataacaat
    28561 tgtttggaca tctgctttga caaagttcat tgtgtcgtaa atagccatac ctgctgtaac
    28621 tgaaccacca ggagaattga tataaagata gatatctttt tcagaatctt gagcgtctaa
    28681 gaaaagcaat tgggcgatga tcgaattagc aagatcatct gttacttggc cgcttaacat
    28741 gatgatacgg tctttcaata aacgtgagta gatatcgtaa gctctttcac ctcgtgaaga
    28801 ttgttcaatg actgtaggaa ttaaattcat aatagagttc ctccttgatt tcgtttagaa
    28861 atagtgtacc ataatttagt ttctaatacc taaaatgtag tatacatttt tggtcaaaaa
    28921 aggtcaaata aaaaacttag gcaaattagt cgcataaacc cgctttatgg tatgataagc
    28981 agagaaacaa aacaaggagg aacaacagat tgatagttgg tattactggc cttatcggag
    29041 tgctgacagg tgctgtagtt gtctatatcg gcatgatact gcaaatgcgt cacttggaaa
    29101 ataaagaaca gcgtagacgt gaattggaat tgaaagtcaa agaaatcgag acgctgaatc
    29161 aattaaataa aaagatcaac gagatcttgc aaaaacggac aacgctgatg gaagaatatg
    29221 tcagctttga tgcatttgat gattgttata tcacgattga cgattttgcg tatctccaat
    29281 cattttcagc gcaaaatagt ttttatctgc caaattatat tttagacgag ctatttaaga
    29341 atatctccca tcgaaaagtg attttatctc cagatgaaac aatgaagatt ggtggatatg
    29401 cttataaagg cggacgcgtg attttagaga attttacgga tagtctgact gaaatgatca
    29461 atgaaaaaaa agctcagttg aagactatga cgcgccagcc gattggtttc ttctcgaaag
    29521 atgatgtttg aagctgatat tttgaagcat tgccgttgca catgagagcg tggtaatgct
    29581 ttcttttttt cttaatgata caatagaact gaacggagtg aagaaagatg ttacaaatct
    29641 atgcccatcg cggaagcagc ggcacccacc cagaaaatac gcttcctgca tttgcagaag
    29701 ctgtacgagt aggtgcagat ggtatcgaac tagatgtcca tctaagcaaa gatggttatt
    29761 tgatcgttat gcacgacgaa gaagtggacc ggacgactaa cggtaaaggg ctgattcgag
    29821 aaaaaacatt ggaagaactc aaaaaattga atgcaggggg caaattcagc aaagaatttc
    29881 cagcagctaa agttcctgaa ttgagagaag tgttaggact gctcctccaa aaaaattacc
    29941 gagggatgct aatgattgaa attaaaactg atcagtatga atatcccggt atcgaagaaa
    30001 aattagccga aacattaaaa agtagagatt ggccttttca acatgcatat tgcagctttc
    30061 atttggattc tttggaaaaa atcgcattac tggaaccgga gatacagctg gacttattga
    30121 tgagtacttc tgataaaaag atccaactag cagcagaaac cccttatata gaaggagtac
    30181 atccaaaaaa tacttggttg ttcgaacatc cagtccaggc agctgatttt ccaaaagcaa
    30241 ttcgtgcatg gacgattaac gatgaagaag aaatggccaa atgtcaagaa ctcaaaatag
    30301 atggaataat aactgatttt ccggagaaag ctcttcggtg gaaacaatca acgaaaagta
    30361 ggtaaaatat ggaaaaagta ttagtgatcg tcggtccgac agcagtcggt aaaacagcgc
    30421 taagtgtgga actcgcacaa ctatttggag gagagatcat cagtggtgat tcattgcaaa
    30481 tctataaaaa tctggatatc ggtacagcaa aaatcaaaga agaagagatg aataatgttc
    30541 cgcatcattt gattgatgtg atcgaaccta ctcaacgtta ctcagccgct gattttcagc
    30601 attcaggtcg acaattgatt accgagattg cgaaccgagg gcacctacct atcatagctg
    30661 gtggtacggg tctctatatc caatcccttc tatatgatta tcagttagga gcgacagaag
    30721 aagcgaatcc tgagattaga aaaaagtatg aaacgttagc tgaaacaatt ggttcccaag
    30781 cattatggaa tcagttgaaa gaaaaagacc cggcagctgc tgagaaaatc cactggaaca
    30841 atcaacgcaa agtgataaga gctctggaag ttttagagac gacaggacat agtatcacgg
    30901 cacctaaaga agagccaaag caattgtatg attacctcat gattggatta gatacgaagc
    30961 gtagtattct ttatgaacga atcaatcaaa gagtcgattt gatgctagca gaaggtttag
    31021 tagcagaagc gcgtaaggtg tatgagcttg gagaagtcca ggccagtcaa ggtattggat
    31081 ataaagaatt tttcccttat tttgaaggga aagaaacatt ggaagaagca acagaacaag
    31141 tcaaactaca ttcgagaaga tacgcgaaac gtcagttgac gtggtttcgt aaccgtttgg
    31201 atgcacagtg gtttgatctt ataagtgagc caaatcaaaa aagtcagatt gagcaaacaa
    31261 tcaaaaaatg gctggaggcg gaataaaatg gaagaaaaag tgatcatcgt aggggtagaa
    31321 accgaagcaa accagcgtta cttttcagag tcaatggaag agctagttca gctgacgaat
    31381 accgcatcag gagaagtcgt attcacaatt acacaaaaga gaccacaagt ggatcggcaa
    31441 acgattatcg gtaaagggaa attacaagaa ttagttcaac aagcggatgc gcatgaagcg
    31501 gatttgatca tctttaatca tgagctaact ccgagacaga gccaactgat taccgatgct
    31561 gttggtcttc cggtaattga tcgcgtgcag cttatcttag atatttttgc gatgcgtgct
    31621 cgttcgaaag aagggaagct gcaggttgaa cttgctcagt tagaatacct gttgcctcgt
    31681 ttagtagggc aagggaaaac attatctcgt cttggcggtg ggatcggaac aagagggcca
    31741 ggtgaaacaa agttagaaac agaccgccga catatacgga ataaaatttt tgctgttaag
    31801 aaagaattga aagaagtaga agctcatcga gagcgcaatc gccaaaaaag aaaaaatagc
    31861 gagatttttc agattggact tattggctac acgaatgccg ggaagtcaac tatcttgaat
    31921 ctattgacac aagcggatac ttattcgaaa gatcaattgt ttgcaacgtt agatccattg
    31981 actaagagat ggcgttttgc tgaaggattt gagattgctg taacggatac cgtcgggttc
    32041 atccaagacc tgcctacgca actgatcgat gctttccatt ctacattaga agaaagtcaa
    32101 aatatggatc ttttgctaca tgtagtcgat gctagttctc cagatcgtat tttacaggag
    32161 cagactgtct taaaattgat ggatgaactg aatatgaaag aaatgccgat actgactgtt
    32221 tacaataagg cagaccagat cgacccagcg atgttcacgc ctacgctatt cccaaatgta
    32281 ttgatttcta ctcagacgaa agaaggtaag atggcgttga tcgaagcaat caaacgtcag
    32341 ctgatggaac taatgacccc ttatacactt tctgtgccaa gcaacgaagg acagaaatta
    32401 agcgagttga gaagacaaac aatggttttg gacgaagcgt acatggaaga aacaaacgaa
    32461 tatgaagtta aagggtttgc aaaaaccaat tcaaaatggt taagaaaaaa ccaataaaat
    32521 tttatttttt taa
//
LOCUS       DAZULR010000032        29268 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.032, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000032 DAZULR010000000
VERSION     DAZULR010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29268)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29268)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29268
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.032"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            290..697
                     /locus_tag="ACG8ZV_001712"
     CDS             290..697
                     /locus_tag="ACG8ZV_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997052.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            711..1112
                     /locus_tag="ACG8ZV_001713"
     CDS             711..1112
                     /locus_tag="ACG8ZV_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997053.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1114..1485
                     /locus_tag="ACG8ZV_001714"
     CDS             1114..1485
                     /locus_tag="ACG8ZV_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997054.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(1521..1823)
                     /locus_tag="ACG8ZV_001715"
     CDS             complement(1521..1823)
                     /locus_tag="ACG8ZV_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HFS4997055.1"
                     /translation="MLMEGKTQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINL
                     YYSNKNYFKIPAAKTRMKKGVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(2081..2194)
                     /locus_tag="ACG8ZV_001716"
                     /pseudo
     CDS             complement(2081..2194)
                     /locus_tag="ACG8ZV_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(2577..3809)
                     /locus_tag="ACG8ZV_001717"
     CDS             complement(2577..3809)
                     /locus_tag="ACG8ZV_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HFS4997056.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            4063..4632
                     /locus_tag="ACG8ZV_001718"
     CDS             4063..4632
                     /locus_tag="ACG8ZV_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFS4997057.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(4810..5250)
                     /locus_tag="ACG8ZV_001719"
     CDS             complement(4810..5250)
                     /locus_tag="ACG8ZV_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HFS4997058.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            5408..6172
                     /gene="map"
                     /locus_tag="ACG8ZV_001720"
     CDS             5408..6172
                     /gene="map"
                     /locus_tag="ACG8ZV_001720"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HFS4997059.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            6204..7127
                     /locus_tag="ACG8ZV_001721"
     CDS             6204..7127
                     /locus_tag="ACG8ZV_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HFS4997060.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            7203..8342
                     /locus_tag="ACG8ZV_001722"
     CDS             7203..8342
                     /locus_tag="ACG8ZV_001722"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MraY family glycosyltransferase"
                     /protein_id="HFS4997061.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            8335..9135
                     /locus_tag="ACG8ZV_001723"
     CDS             8335..9135
                     /locus_tag="ACG8ZV_001723"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFS4997062.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            9135..9962
                     /locus_tag="ACG8ZV_001724"
     CDS             9135..9962
                     /locus_tag="ACG8ZV_001724"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFS4997063.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            9967..10674
                     /locus_tag="ACG8ZV_001725"
     CDS             9967..10674
                     /locus_tag="ACG8ZV_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFS4997064.1"
                     /translation="MRSVCIATFNGGRYLREQLDSILSQLSAEDEVVISDDGSVDDTW
                     DILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWLETKVKKITD
                     YFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYIGAGMAFRSS
                     LKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIETHSKLRQKIS
                     WRVHLITALIKRKWFKR"
     gene            10774..11640
                     /gene="rfbA"
                     /locus_tag="ACG8ZV_001726"
     CDS             10774..11640
                     /gene="rfbA"
                     /locus_tag="ACG8ZV_001726"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HFS4997065.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            11654..12226
                     /gene="rfbC"
                     /locus_tag="ACG8ZV_001727"
     CDS             11654..12226
                     /gene="rfbC"
                     /locus_tag="ACG8ZV_001727"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HFS4997066.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            12248..13276
                     /gene="rfbB"
                     /locus_tag="ACG8ZV_001728"
     CDS             12248..13276
                     /gene="rfbB"
                     /locus_tag="ACG8ZV_001728"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HFS4997067.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTSILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWQPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            13374..14225
                     /gene="rfbD"
                     /locus_tag="ACG8ZV_001729"
     CDS             13374..14225
                     /gene="rfbD"
                     /locus_tag="ACG8ZV_001729"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HFS4997068.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLPYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEALGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            14260..16293
                     /locus_tag="ACG8ZV_001730"
     CDS             14260..16293
                     /locus_tag="ACG8ZV_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997069.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFSLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMIAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFVALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            16337..17617
                     /locus_tag="ACG8ZV_001731"
     CDS             16337..17617
                     /locus_tag="ACG8ZV_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HFS4997070.1"
                     /translation="MKIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGVGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFTVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNTIGSSLMTLALLISGFASSFERWYVRIIGGIAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQVLLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYRWVPIIYILLAMAVHRYDEPEVTEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            17827..18633
                     /locus_tag="ACG8ZV_001732"
     CDS             17827..18633
                     /locus_tag="ACG8ZV_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4997071.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            18645..19865
                     /locus_tag="ACG8ZV_001733"
     CDS             18645..19865
                     /locus_tag="ACG8ZV_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4997072.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGKVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            19855..21441
                     /locus_tag="ACG8ZV_001734"
     CDS             19855..21441
                     /locus_tag="ACG8ZV_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFS4997073.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLYINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAQPQNSNYVKVLEVIQQTKQDEIIQQIPFNNFTGENETLSFHVSELA
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKDLPEFFLTDIAG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHYLIENNTRLD
                     QTLKTTINRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSLCIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVLREEVNQAKQLAEGAKAGFELRILCEK
                     ERSFLVEAVAQNGQSWIIEM"
     gene            21480..23618
                     /locus_tag="ACG8ZV_001735"
     CDS             21480..23618
                     /locus_tag="ACG8ZV_001735"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFS4997074.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEVQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRQENGHISLATNSALEMAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDLIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPAEHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVHPGRISGFYEITYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYPNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTAMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(23986..24969)
                     /locus_tag="ACG8ZV_001736"
     CDS             complement(23986..24969)
                     /locus_tag="ACG8ZV_001736"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFS4997075.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
     gene            25347..26738
                     /locus_tag="ACG8ZV_001737"
     CDS             25347..26738
                     /locus_tag="ACG8ZV_001737"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HFS4997076.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            26754..27794
                     /locus_tag="ACG8ZV_001738"
     CDS             26754..27794
                     /locus_tag="ACG8ZV_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFS4997077.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRKIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            27813..28898
                     /locus_tag="ACG8ZV_001739"
     CDS             27813..28898
                     /locus_tag="ACG8ZV_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HFS4997078.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            28931..>29268
                     /locus_tag="ACG8ZV_001740"
     CDS             28931..>29268
                     /locus_tag="ACG8ZV_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-1,6-N-acetylglucosaminyltransferase"
                     /protein_id="HFS4997079.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGADYPIKD
                     NEYIYNYFKK"
BASE COUNT         9509 a         4788 c         5844 g         9127 t
ORIGIN      
        1 ttttgagggg aagtacatat agttgttgat atagttgcta atattgttag ctaatttgtt
       61 agtaaaactg tatacgaatt tagatagtaa aaaaacagtt tgttccttat atagaggcac
      121 ttttactact gattaaatgt cagatatgct tacaaatata cttataaata tgcttacaaa
      181 attagctaat atttccgttg acaaagcttt gttactattg ttaaactaaa ttgactagca
      241 aaagtgaaac ataaatttat taaataaatg taaaaattag gagaaatcaa tgtcttatag
      301 agtacaatta ataatttcag aagatgtaga aagtcagcaa tttggcacta atgttattaa
      361 taaagtaatt aatccagctc tttctattaa tgcgccttta attcctactg ctttatcatt
      421 ttctgtaaca gctgtggtgt ctgagataga ggatacagaa aagataaaaa tagtagaaat
      481 tgaagtttta aacaagaatg aaaaacaaat tttttctacg ggtgaagtat cggtaagctt
      541 gcctcctcaa gttaacgata taaactttaa tataaacgcc agaaatgtct tggttgaaga
      601 agcaggagag cattatgctg ttgttaaatt taatggaact gagattggaa ggcaaatctt
      661 tgatatcaag gtcaacaaac cagtggaaaa aaattaagga gacgatacgg atgcttgata
      721 tagtaccatc aaatacacat cggagtggta gcttaataaa ttttgctgcg atttttgctt
      781 gcgcatcggt aattctagca tctccagttg ttgtggatgc aagttctact ccgaaaacta
      841 aaaatgataa tcaacttgta attactacaa aaaatgagat taacacaatt tcaagtaatg
      901 atggcaaaat ttttgatgtg ataaatacgg ttttaaaaag aaaagctgaa atcaatataa
      961 aatatgatga agatttaaac ttgtatttct ttgttatcaa aacaacatct gaattgtttt
     1021 cctcagatta cgatgttttg gatactctcg ataatgtatt atctgactat aaatatatgg
     1081 ggaaatctgt agtagcaact ttgggggaat aaaatgtttg actttaatga atatttatct
     1141 atttccaaac aaattgaatc agatgataaa tataattcta aagaatctta tagaagaact
     1201 gctgtttcaa gagcatacta cagtgctttt aaaaaatctg atgagtattt gaaagaaaat
     1261 tatgatatta tttataatgg aagtagcgga aaaggaagcc accaaaccgt ttggaatttg
     1321 ttttcaacag ttaaggaatt gaatacctta ggaatacata atagtgggta tagaatgtta
     1381 gagaaaagaa aatgtgctga ctatattcct aatgaaacca ttacgaaaac agatatggcg
     1441 ctgatgaatc gagaagcaga aaaaataata aacaaactca cctaatgaat ttcaagcgag
     1501 tttgtttgtt atttttttat ttaatctttg tatctttctg gatcaacgaa agtatacttt
     1561 atatagtcat aacgccgatg atcgctacgt gcgtccggca cgtcagtcac gatatcaaac
     1621 aaaaagtata cacccttctt cattctagtt ttcgcagcag gaattttgaa atagttctta
     1681 ttagaatagt agagattgat taataagcta tcttcgattg ctaaaaagaa aacttctgaa
     1741 ttccatactt tataaaaatc tttgataaat ctattcgaag ggtcaaattt aaaccataat
     1801 tgtgtttttc cttccatcag cataaaagtt cacctcaaaa agagtatacg aacgaatgtt
     1861 ctttttgtga aggcggaatt taatatactg aataatagaa aacaagtact tgtgccaaat
     1921 tatgtgccaa aaaaattcga attcaacaaa atgtaaacaa atagaaaacc ttctatatta
     1981 agatttcctg caataacaaa cacaacagaa gacgtgtaat agttagtcag gaacgtacaa
     2041 ataacccctg tatcctttgc ggtacagggg gttattttgt ataagtagac attgtagttt
     2101 ctaaactgct atgtcctaaa cgtttcgata cgctaagtat atttactcct tgataaagta
     2161 aaatagatgc atgcgtatgt cttagtccat caataaacag tcgaagagaa aatagggaaa
     2221 aattgattac taaagaaaaa cttactaggt cgacggtgta gttgattttc atacttcaat
     2281 agattcgaat taaacgattt cgattggctt ataccagtcc tatccaacga aagatatatc
     2341 gttcttaact ctagcggtat aacttgaagc tttacgtaaa gccaatggga atgaactgga
     2401 gatgactttt tattattttt agtaatagct gatgggttaa tacttacaac tttccttttc
     2461 aaagtaccat ataaaaaaac ggtggggttg tttagcgaaa taaaggatct aagccaatag
     2521 cttagatcct ttattctatg ctttatatta ttttttgcat gtgtgcgaaa gtatactcaa
     2581 gcccaatcgc catttcggaa aatcggtact gtagagccat cttcacggat tccgtcgata
     2641 tccatcttgt cagatcctac catgaaatct acgtgggttt gacttctatt caatccagct
     2701 tctgctaatt cttcatcgga catttctgta ccgcctttca cactgaaggc ataagcagaa
     2761 cctagtgcta agtgattcga tgcgttttca tcaaataatg tattgaaaaa gatgatgcca
     2821 gattgagaaa taggtgaagg gtcaggtaca agtgcgactt ctcctaaacg acgcgcacct
     2881 tcatctgtat caagcagttt tgctaagaca tcttctcctt gttcggcaga aaaatcaaca
     2941 acttttccat ctttaaaagt aaatttcata cccgagatga tggtgccagc ataactcagt
     3001 ggctttgtac ttgaaatgta accatctact cgatgactgt caggtgctgt gaacacttct
     3061 tccgtcggca tatttgccat gaatttttct ccacgagcat tatagcttcc agcgccttcc
     3121 caaagatggt ttttaggcaa tccgataatg atatctgtac cgggagcagt atagtgaagg
     3181 gcagaaaatt gttctcgatt caattcttct gctttttttg ctaatttttc atcatgcttc
     3241 ttccatgcta agacagggtc ttcttcatag acacgagtcg ttttgaaaat ctgatcccat
     3301 aatgcctcaa cttgtttttc ttctggcagt tctgggaaga cttttgctgc ccattgttta
     3361 ccagccgcag ccacgacagt ccaactgact ttatttgctt gagttgcctt gcgtaaattc
     3421 attagtgctt tgccattcgc tgattgataa gacgctactc gatggctatc tacaccagca
     3481 aatgcatcgg gatcggcaga aacaacgctg atcctgcttg ctcctttttc aagccattca
     3541 tccgcttgat cgattttaga ttgtggtaca ttctcaatac gatccgttgc agcatgtaaa
     3601 agaaattctc tttggatctg gtcgtcagtc cattgaacga taacctcagc ggctcctagt
     3661 ttataagctt cttgtgtgat caatcgagca aggggtgcct gttccacgct gatctgtaaa
     3721 acaactgtgt gtcctttttc tgtggctacg ccagtttctg caattaagcg tgcatatttt
     3781 tttagaagtt cattaaaatc agataacata ataaaaattc ctcctcacca ttttttctgg
     3841 taactattag catgatacca tttaattatg attcaaacaa tgaggcttta aataaaaaaa
     3901 ggaggttatt tttttaaggt taagtttcat gatatatgtt actacttgct atttcagctt
     3961 gtgaagaaaa tcaaaaacta attttgcata tcaaaaaaac atgttacaat gaaattaatc
     4021 aatggtggaa gcgttataaa aaaattaagg agattaaaaa atatggcaag aaaaaagacg
     4081 attactagag aacagatttt ggcagctgct tatgaagtag ctgccaccga tggatttaca
     4141 cgatttactg cgagaaacat cgcgaacaaa atgaattgtt ccacgcaacc gatttatctt
     4201 gagtttaaaa atatggatga cttgagacaa gctctttttg agcagatcta tgatcattta
     4261 caatatgaag tgttcactgt tgagcataca gggaatacga ttatcgatct tgcttttaat
     4321 tatatccatt ttgcaagaag agagaagaag ttgtatcgtt cactgtactt agaagaatat
     4381 ggtggaggaa aagagatgca gaatttctct tatacttact ttgtgaatac agtgaaacgc
     4441 gatccagctt atgtgaatct ttcagaagag cagatcgaat ctttgtataa tgggacatgg
     4501 atcatagcta ctgggatcgc agctttgatg tcttcaagca tcatccatcc aactgatgaa
     4561 cagattgaaa agatgatcca agacagtata gatgctatct tgaaattcaa agaaccaatc
     4621 gaaatcgatt gaatatactc aaaagttcca caaatcagta ggtaacaaga gatgtgtcaa
     4681 aataaggaaa agttcgtttt tcttacagcg tatgcatttt taactcccga agaactcttc
     4741 catgaatgca atgaataaaa gagccataca gattgaataa atctggatgg ctcttttatt
     4801 gcaagtatat taaatttttg cgactagttc tttagcgaaa gcttctaaat tttcgatatc
     4861 ttcttcttca gcattcagat ccactttaac attttcggct ccttttgatg cgcctgtttt
     4921 tgcaaaagca gcatcgaaat catccaccga tttgcagaat tcatcgtaaa aagtatcacc
     4981 agatccgcag acaccgtaaa tttttcccaa tagatccaat tcttgcaagt cttcataaaa
     5041 gtctacgatc tcatcaggca gatcgccatc atcgtatgta taagtagcta ctacgcaaat
     5101 atctgcctcc tcgaattcat ctgcatctac ttgggtacat tcgttgattt cgacttcgat
     5161 atccagattt tcaaatgctt ctgcaacaat atcggcgatt tcttcagtgt ttcctgtcat
     5221 gctagcatat acgatttttg ctaaagccat gatgtgcctc ctcgtttata attatttaac
     5281 aattatgaat tataccaaaa catcattgaa aagaaaataa aacctaaaga cacctgggga
     5341 atgtcatttg gctaaatgta tgccgctatg ttaaaatgag agggatttgt aaaaaggaga
     5401 cgaaaatatg attactttaa aatcagcacg tgaaattgaa atgatggcag aatctggagc
     5461 tttattagca gatgtacata aaaatctgcg tgattttata aaaccaggaa tcacaagttg
     5521 ggatattgag gtatttgtca gaaactatat cgagagtcat ggcggaattg ctgcgcaaat
     5581 tggctttgaa gggtatgaat atgcgacttg tatcagtata aatgatgaaa tttgtcatgg
     5641 attccctcgt aaaaagcctt tgaaaaacgg tgatttggta aaagtcgata tgtgtatcga
     5701 tttgaaaggc ggcatttctg attcttgttg ggcctatgta gttggagaat ctacacctga
     5761 gatcgaccga ttgatggaag taacgaagaa agctttgtac atcggtattg agcaagcaca
     5821 agtagggaat cggattggtg acatcggtca tgctatccaa acttatgtag aaggcgaaaa
     5881 tctagcgatc gttcgtgatt ttattggtca tggcgttggt cctacgattc atgaagaacc
     5941 agcagttcct cattacggag aagctggaaa agggttgcgg ttgaaagaag gcatggttat
     6001 cacgatcgaa cctatggtta ataccggaac ttggaaaatg aaaatggatc ctaacggctg
     6061 gactgcgtat acaagagacg gcggactttc ttgccaatat gaacatacat tggctattac
     6121 taaagatggt ccaagaattt tgacatcaca aggagaagaa ggcacttatt gatctatcca
     6181 gtcaataggt acgggagagg tacatgaaag tttggaacaa aataaaacaa aatgaaaatc
     6241 tgatgcgctt tattgagacg actcaaaagc gcatcactga ttcagaaatg agtacgacct
     6301 ctgtcgtcgt tgcttattat ttactcttgt ctttatttcc attgattatt gcttttggta
     6361 atattttacc gtttctccac atcgatcaag agactgtact gacctattta cgagaagtga
     6421 ttcctgagac cgtttaccag tttatcggtc ctgcaatcaa agaccttttg acacaaagtt
     6481 caggaggctt gttatccgtt tctgcattag cggctttatg gtctgcaagt caaagtatca
     6541 atgctttgca aattgcgatg aataaagcgt atggcgtaga aaatagaaaa aattttttga
     6601 tcgtccgttt cttctcacta attgtcattg tcttgttcat gattgctatt agtggggtaa
     6661 ctatcgttct tgggttggga cagctgattt tggatgctat tcagccaatc gtacaaatac
     6721 ccgtgaactt tatcgatcag ttccaaactt tgaagtggcc aatcacattg gtagctttat
     6781 ttgtcatcat gttcttgatt tatttaattg tccctaatgc tcagttgaag ttgaagacga
     6841 tcattccggg cacgatcttc gctactgtcg gctggatgct gttatcacaa gtgtttagta
     6901 tctatgctag gtattttgca acgaggatca gcggttatca gatcatagga agttttattg
     6961 tactcatgct ttggcttaat tttgctgcta cgatcatcat tttgggcgga atcatcaatg
     7021 cagttgttca agaatacgtg acgggtcatc aaatcaaaaa acgtcgagat ccaagccgaa
     7081 aatggttcaa taaattgaaa actaaatttt ctcataaaaa aaagtagaaa caagagttct
     7141 tattgtaaat ttatatcagt aatttataat aattatgact cttaattaaa gtaggtgccc
     7201 atatgcttgt ttcttttagt atggttataa gattttttct gacaatttta ttatcactga
     7261 tattaacacc tgtattcaaa atcatttcag tacaaacagg tatggtcgac aaaccaaatg
     7321 aaagaagaat aaataaagtt ccaatgcctt cagcgggcgg actgcctatc tttatttcat
     7381 ttgttatatc gactttattc ttattccgta aaattatccc tcaatcgtat attgtaccga
     7441 tcttgattgc ttctttagta atcatagtca caggagtgct cgatgataaa tatgagctga
     7501 cacctaaaca aaaaagtata gggatcttga ttgcttctct tattatttat tttgtagcag
     7561 atatacgtat tgattccttc acgcttcctt ttattggata tatccaacta ggctggctta
     7621 gttttcccgt aacgattttt tggatcttcg gtatcacgaa tgcggtcaat ctgattgacg
     7681 gtttggatgg gctggcggca gggatttcat tgatcggttt aattacgata ggaatcattg
     7741 gatatttttt cctccatgct tctacagtgt atattccagt tgttattttc tgtcttgtag
     7801 caagtattat cggttttttt ccttacaatt tttatccggc aaagatttat ttaggcgata
     7861 caggagctct attcctaggg tttatgatgg ccgtcctttc actacaaggg ctgaagaacg
     7921 tgacttttgt ttcatcgatt tctttgctga tcgtcatggg agtgccggta acagacacgt
     7981 tttttgctat cattaggaga aaagcaaacc gtgtttcttt ttctacagca gataaaaaac
     8041 atcttcatca ccgactaatc agtttaggct ttactcataa aggtgctgtc ctgacgattt
     8101 atgcgatggc tttgatgttt tctttcacag ctatggtcat gaattatact ggaagaatcg
     8161 gaacgatcat attgattatt gccatgttgt ttgctgcaat tttattattt gaattgattg
     8221 gtctgatcaa tgagaaacat cagtttattt taaaaacatt gcgattttta gggaataaag
     8281 agtaccgtac gcaagtaaaa cagaaatatt tgaagaaatg gaaccgtcat atagatgaat
     8341 aacaaattaa accagccgat ccttattagt attgtgacgg caaacagtga taaaattttt
     8401 cggacactag ataattttat ttcaactgta aaagatgaaa cagcagtaaa aatccgaatt
     8461 tttgacaaca attcacttcc cgagtacaaa aaaagactaa cagagtatag gaaatatccc
     8521 tacatcgata tctattttca tgatgaaaat tccggatttg gttatggaca taatcacaat
     8581 ctgatagcta gcgattctcg ctatggcatt atttgtaacc cagatatttt agtggatgaa
     8641 gagacagtta cagcattggt cttgttattg aaagaacatc cggaatgtgc gatgttagca
     8701 cctaagattc ttaatgaaga tggaacaact cagcacctca tccgtgagca gctggctgtt
     8761 tttgattacg ttttgcgctt tgtgcctttc aaatgggtca aaaaaaagtt tgacaaacga
     8821 ctggctgtgt ttgaatgccg aggattgcct actgatgcta atagttatgt acggatgatc
     8881 tcaggtagtt ttatggtagc tgatattgat aaatttaaag agataaaggg gtttgatgag
     8941 cgtttcttca tgtactttga agacaacgac ttgtgtttga gttttgaaaa agcaggttac
     9001 aagttattgt acacaccctt ttatgcagtt atccattttt acgggaaggg tgcgcatcga
     9061 aatgcaaaac tgtttcgcgt gtttttgact tctatgatga aatttttcaa taagtggggg
     9121 tggcgttttt tctgatgaaa ccagaaatat tagtagtcgt tgtgctttat cagcaactat
     9181 tcagtcaatc tccagcttat ggaccattaa gcaaagcact tagcgaaaag caaattcagc
     9241 ttattattta cgataatagt cctcaaaggc agcaaaatga gctgtttgaa aaagaaaata
     9301 tcgtttatca tcatgatccg caaaatcctg gtttagcggt ggcttataat tttgcgttgt
     9361 ctcaagcaga tgaaggaaca cgttgtctcg tcactctgga tcaggatacg aggctagtcg
     9421 acgattattt tgaactattg cgtaaagtaa cctttacaga tgaatgtgtt gctgcagttc
     9481 cgatgatttt ttctgggagc cgacaagttt ctcccctata ttcagatcgt tatatcaatc
     9541 gtacagctca agcagtagaa gttgaaggcc caacagctga acgaatcatg gcaatcaatt
     9601 caggtgttgc ctggtctgtc aaatttctaa aaaagattgg cgggtttaat cctgcttttt
     9661 ctttagattt tttggatcat tggctgtttt ggaaagtgga tcagttggaa aaaactgtgg
     9721 agatccttcc tgtacgaatg gaacatgatc tttcggtttt agactatgaa aaagtttcaa
     9781 gtaatcgata ccgttctatt ttacaagcag aaaatcgatt ttatcatgaa tatgatcaaa
     9841 ggcatttatc cagtcaccga cgacaattat tgttaagaac agctaaacag ttcttgaccg
     9901 tcaaaaaccg gcatatctgg cggatgactt tgcgctcata tgttaagaat tggaaggtgt
     9961 gaattcgtgc gttcggtttg tatagctacc tttaatggag gcagatattt aagagagcag
    10021 ttagatagta ttttatctca gctttcagca gaagatgaag tagtcatttc tgatgatggg
    10081 tcagtagatg atacatggga tatattaact gaatacgcag aaaaagataa gcgaatccag
    10141 cttttttcgg ggcctcgtca aggattgatc gctaattttg gttatgcgat ccagcagacg
    10201 aaaggagatc taatcttttt ggcagaccaa gatgatgttt ggttggagac aaaagtgaaa
    10261 aagatcactg actattttga gcagaatccg gatcagctag tagtagtttc tgatttaatc
    10321 attgtggaca gcgagctgca agagatccat gattcgtatt tttcgtttcg aaattccaaa
    10381 gaaggatggc ttaataatgt gataagaagt cactatattg gtgctggtat ggctttccgg
    10441 tcttctttaa aacccgatat tttgccgatc ccgtcagaag tgccgatgca tgatatgtgg
    10501 attggtttgc tgggaggaaa gaagactggg ttcctaagag aaccgttaac tctgtaccga
    10561 agacatgatt taaacgcgag tgagattgaa acacattcta aattacggca aaaaatttct
    10621 tggcgtgttc atctgattac ggcgttgatc aaacgaaaat ggtttaaacg ttgataaaag
    10681 atgtttaaat ccttaatatt tccatgacaa atataacaat tgatgagata ataacaaagt
    10741 gaaatttgaa atcaaaaagg agagcagata tccatgaagg gaatcattct tgctgggggc
    10801 agcggaacac gtctgtaccc tttaacaaag gcaacatcga aacaattgat gccgatttat
    10861 gacaaaccaa tgatttatta tccaatgtct actctgatgt tggcgggaat caaagaaatt
    10921 ctgattattt caacgccaca agatacacca cgtttcaagg aattatttgg aaacggaaat
    10981 gatttaggac tgcagatcga atatgcagta caagaaagtc cagatggatt ggcacaagcg
    11041 tttatcattg gagaagaatt tattggagat gatagtgtct gcttggtatt aggggacaat
    11101 atttactatg gtggcggtct gtctaaaatg ttgcaacgag cagcttcaaa agatacaggc
    11161 gcgacagtat ttggctatca tgtcaatgat ccagaacgct ttggtgtagt agaatttgat
    11221 gagaatatgc aagctttgtc gattgaagaa aagcctgctc agccaaaatc aaattacgct
    11281 gtaactggcc tttattttta tgacaatgag gtaatttcta tcgctaaagg tatcaaacct
    11341 tcagaacgtg gagaactaga gattacggat gtcaataaag catatttgga taaaggaaaa
    11401 ctatccgtag aacttatggg acgcggattt gcttggcttg atacaggaac acatgaatca
    11461 ttgcttgaag catctacctt tatcgaaaca attgaaaaac gtcagaactt aaaagtggct
    11521 tgtttggaag aaattgctta ccgtatgggc tacatcgata aggaacaatt gctggccctt
    11581 gcacagccat tgaaaaaaaa tcaatacggt caatatttat tgaatttggc cgctgaataa
    11641 ggagtcctta cagatgaaag taacagatac aaaattaaca gatgtcaaaa tcgtagaaat
    11701 ggacgtcttt ggcgatcatc gcggtttctt cacagaaagt tattcaaaag caaaatttgc
    11761 agaacatgga ttgaaatatg actttgttca agacaaccat tcactatcag ctgaagctgg
    11821 tgtccttcgg gggcttcatt tccaaaaagg agaagctgca cagacaaaat tgattcgggt
    11881 agtcactgga gcagttttag atgtagtagt ggatatccgc aaaggtagcc cgacttatgg
    11941 tcaatgggac ggatttatct tatctgaaca taatcatcga cagttgcttg tacctaaagg
    12001 atatgcccat ggattcgtta ctttgacacc aaatgtgaac ttcctttata agtgtgataa
    12061 ttactataat gcagaagcag atgggggcat cgcatttgat gatccagatt tagcgattga
    12121 ttggccaatt gatccatcaa gagcgattat gtcggaaaaa gatcaccgtc atccgacatt
    12181 aaaagaattt gaagcagaaa atccatttgt ttacggagaa atctaagaat taaggagaaa
    12241 ttttcttatg aaaaacatca ttgttaccgg aggtgccgga ttcatcggct ctaatttcgt
    12301 tcattacgtg gtaaacaatc atccagaagt gcatgtcact gttttggata aactgactta
    12361 tgcaggaaac aaagagaact tggccggact tcctagcgat cgcgtagaat tggtcgtagg
    12421 agatgttgca gatgcagaat tagtggaccg tctagtaaaa gaagcggacg cagttgttca
    12481 ttacgcggca gaatcccata acgataattc attaaaagat cctttcccat ttgtacaaac
    12541 gaatatcatt ggtacgtata cacttttaga agcttgccgc aagtatgatg tacgctatca
    12601 tcacgtatct actgacgagg tttacggcga tcttccatta cgtgaagacc tgccaggaca
    12661 tggggaaggc gaaggagaaa aattcactgc ggaaacacca tataatcctt caagtccata
    12721 ttcttctaca aaagctggtt cagatctgtt agtaaaagca tgggtgcgtt cttttggctt
    12781 acgtgcaacc atttcaaact gttcaaacaa ctatggtcct tatcagcata ttgaaaaatt
    12841 tattcctcgc caagtaacga gtatcttaag cggtattcgt ccaaaattat atggcgaagg
    12901 aaagaatgtt cgtgactgga tccatacgaa tgatcattct tcagcagtgt ggctgatttt
    12961 gacgaaaggc agaattggcg aaacctatct gatcggtgca gacggtgaag aagataataa
    13021 gaccgtgatg gaattgatct tagaaatgat gggccaacca aaagacgcat acgaccatgt
    13081 aaacgaccgc gcagggcacg atttgcgtta tgcaatcgat tcgacaaaat tgcgagaaga
    13141 gctaggttgg cagcctgagt ttacgaactt ccgtgatggg ttggctgaca cgatcaaatg
    13201 gtacgaagaa catgaagact ggtggaaaaa agaaaaagag gccgttgaag cagcatatgc
    13261 caaaaatgga caataataca gaggaaattt cactgtatta atggaaaaac acatgtgagg
    13321 caggcgctcg cctgtctctt ttttaaaata aaaatcaagg agcggataac catatgtttt
    13381 tattaactgg aggaaatgga caattaggta cagaattgcg ccatttatta gatgaaaaaa
    13441 atctgccata tgtttcaaca gatgcaaaag acttggatat cacagatgct gagaaaacaa
    13501 tggcttatat tacagaatta aaacccgatg ttattttcca ttgcgcagct tacacagcag
    13561 tagataaagc agaagaagaa gcaaaagaat tagatgagaa aatcaatgtc gatggcacaa
    13621 gaaatgtagc acttgcagca aaagctgtga atgcacaatt cgtctatatc agtacagact
    13681 atgttttcga tggaaaaaac aaaaatgtag aatacgaagt agacgaccaa acgaatccac
    13741 taaatgaata tggtcgtacg aaattattag gcgaaaaagc agtagaagag attttagaag
    13801 actattatat catacgaact tcttgggttt tcgggatcta tggacacaat ttcgtcttca
    13861 cgatgcaacg cctagcggaa acccgcgaca aactgactgt agtaaatgac cagtttgggc
    13921 gaccaacttg gacacgtact ttggcagaat ttatggtata tgtcatcgaa gaaaaagcac
    13981 catttggtat ttatcatttg tcgaacgaaa atagctgttc ttggtatgag ttcgcaaaag
    14041 aaatattgaa agatacagat gtagaagttg cacctgttac gtcagaagaa tttccgcaaa
    14101 aagcaacacg tccgcagtat tcagtcatga gcctgaaaaa gacagaagcg ttaggttttg
    14161 tcataccaac ttggcaagaa gcacttgcgc aaatgctgga agctgccaaa aaaatgaata
    14221 agtaatttcc tttttatcaa atagaatttg gagcatgata tggaaaaaca aacaagaagt
    14281 gcacgacgaa aagaaaagcc aaaagcgaat caggcagatt cgaatttggt gcttgacctg
    14341 tttctaaaac tccgctatct tattggcgtt ttagtcatcg tggtcatcgt tacttttaat
    14401 ttaaacggaa gttcacttgg tgtttgggat aaatatgtgt cgcaaagaga cgatgggaaa
    14461 aaaactgatg tgatttttgg acagaatcgg gaagtgcggt cagacgaatg gctggtgcag
    14521 acaccttttt acctctcaca agctgaagag gacttttcgt tggtgaacga ggattattca
    14581 ttaaacggac aaaacatgat cattgcgtat aattctcctg taaaggatat tacggttatc
    14641 ggaaaaccat tcaactgggg attctttttc ctcggaagag atcgaggact ttccttttat
    14701 tgggcgatga aattagtcgt catggtcttg cttggattcg aagtactgat gatattaacg
    14761 aagaggaaaa aagctctatc gctaatcggt gcatttgcgc tgacattttc tccagcagtc
    14821 cagtggtggt tcatgcaaca tgtgggcgat ttgattttct ttactttggg actgatgatt
    14881 gctttttatc attatttcta caatcatgat aaaaaatggc tacgaacgtt gatgatgctt
    14941 ttggtggtta ttttcggtat tgggtttatt ttagtgattt acccagccca tcaagtgatg
    15001 ctggcgtact tgctgatttt ttattttgtt ggcctgctta tttactatag caagaaagtt
    15061 tcatgggatc tgttggatgt agtgttgatt ggaggggcag ttttatttat tggcggagtc
    15121 atggttcatt tctggctaac gtcaaaagac gcattgttag cttctttgaa taccttatat
    15181 ccaggaaaac gggtaagtac tggaggaaag tggacgattg gcgaattttt ttctttcctt
    15241 acaaattgga aaattccttt tgaagatatc aactattcga ataactctga agtggccctg
    15301 ttctatcact tttttccaac tgtattccta gcaagtccat ttgtgttatt tggcaaaaaa
    15361 gatagcgaac aaaagttact gggacgtatt ttgatgattt tttgtctgtt ttctatcttt
    15421 tggattaccg ttgggttgcc aaaatggcta gcagaaatca ctctgctgtc ttatgttcct
    15481 ccattaagag ccatccttac ttttagtttt gcggcttgtt tattatcgat ctggtttatc
    15541 gcttatattt ggagagaaga tgttattcct atttggtata aattcatttt gttggcagta
    15601 aatgcatggt cttatttcta tgcgattacg cattcgaaaa tggataatta tttttcggat
    15661 tttgaaacca tcgcagttgc tgtgttggga acagtgattt tagcttttgc attatttggc
    15721 tggagacgct tgttttacct cgcttttgtc gccttagtta tcgtatctgg ctttttcgtc
    15781 aatccagtcg tagaaggtac aggagcgatt tttgaaaaaa cactggcaaa agaaatccaa
    15841 aaaatcgatc aacaagatcc tggtaaagtt tggttgtctg aagatgaatt atataacttc
    15901 accccaacat tgggagtgaa atccttcaat acagtacgct tttatccaga tatagctgca
    15961 tggaagaaaa tcgatccgaa agaagaatac gagaagtatt ataatcggta tgctcataca
    16021 agagctttta tcgctaagga agatacaaag ttcattttag atcgtccaga tatgttttcg
    16081 gtcacgttga attttgaaga cgcagaaaaa ttagggatcg actatgtgat cagtaaacga
    16141 ccattaactg attacaacca attatatgaa gcgcagttca cgcagctata tggaccggat
    16201 aaagacggtt atatgatttt taaagtagaa tatccggatt atccagatgt accacaaaca
    16261 caaactcagg aaaatcagct agtcgtacag taataggcta gctgagaata atcctgaaat
    16321 attagtagaa aggagagtga agataattca agcaatcgta caaaaatttg tcaacaaaat
    16381 gagtgtcggt ttcttgcttt tgttgctgac gctagtcttt tttgtttgga cagcaggggt
    16441 aggttttcca gcaactttgt ttatatataa caatagttca ttacttatcg cttttagtgt
    16501 ggctattttg ctcattttaa atgtttataa agcaaaaggc gtcgattttc tttatctagg
    16561 tgttgcgctt gcccttttca ttttcttttc ttactttcgg gaattaagaa atgagtcttt
    16621 atttggagac ttactgtttc ctttgattat tttattttgt ttagtaatta aatggatcga
    16681 gtggacaaaa tgggatcgcg gtatttatct gattgtcttt acggtcttcc tcggaatcac
    16741 gttatatcgt gtatttacag agatccaagt accagaagga caaagcatct gggctccagg
    16801 caattcgctt tctgatattt ggatcaatac gaatacaatc ggaagttctt tgatgactct
    16861 tgctttattg atcagtggat ttgccagttc ttttgaacga tggtatgttc gaatcatcgg
    16921 tgggatagca gtcgttgcag cctttttagg tatttgggtc tgccaatcta gaggtgcatt
    16981 agtcgcgttg attgtttttg cgatattgga tcttttacct aaatcgttga tgcgtgtcat
    17041 tcgtgcgcca tttattgcct acacggttac gattctttta gctttgccga tttcttatct
    17101 ggcggctgtc tctgaaaaag tcaatttgtt taccggtcga gaagatattt ggcataaatt
    17161 ctatcagacg ctaggagaaa aatctgaaca agttttacta ggaatgaaaa catttatctt
    17221 ccagcgagga aaccaatttt taggaaacca caatagttat aattctattt tgaatatcta
    17281 tggattgata ggatttggga ttgctgcttt gctgcttatc ctttttattg gtcgcttaac
    17341 gttgaaagca gatttatcca acgggcagat gacttttatc tgggcctttt ttgcggtgat
    17401 gatgcagtca tttatggagg atacattgac ttcataccga tgggttccga ttatttatat
    17461 cctgttggct atggccgttc atcgatatga tgaaccagaa gttacggagg aattctatgt
    17521 tatggaagag gcatatgacg atatgactta tgatgataca tcttatgagg aacaaccaga
    17581 tagcgctcat tcttccagga tccaacgcta tcattgatag gcacaaaata cgagagaggc
    17641 tgtgacaacc gtcgcagcct tttttggttt attgcaattg tctagcatct tctgtaaaat
    17701 agaaacgtta gagaaaatct tgtatcatag aaaattaaga aagaaataag aacgcagctc
    17761 ggtaccaaaa atatggtaaa atggcacttg actgtaattc actgaaaatc gcttggagga
    17821 acacaaatgt ttaaagattt gtatttattt atgaaggaca tttatcagaa cagaaaatta
    17881 ctgctacagt tttcgatcaa tgacttcaaa tcaagatatg caggatcgtt tttaggaatc
    17941 ttatgggcgt ttatcaatcc gctatttact gtattgattt attggctggt atttggtgtt
    18001 ggactgaaag cacaaatgat cgatgcaaaa tacccattta tcgtatattt agttaccggg
    18061 atgattccct ggttcttctt ctcagatgca tttgcatcaa ctacggttgt ttttcgggaa
    18121 tatacttatt tagtaaagaa agtcgtattc aatattcgta tcttgcccac gacgaaaatc
    18181 ctatccaatc tgtacaccca tttattcttc attctgattg gcatagctgt cgcgcttata
    18241 aatggtatat atccttcagc aatgtcttta cagctgattt attatttatt ttgcatgtgt
    18301 gctttcttga caggattgac ttggctgacg gcatcgatcc aaccattttt acctgatatc
    18361 atgcaattaa ttacgatcgt gctgcagttg atcatgtgga cattaccgat attatggagc
    18421 cctaatcagt ttgattcagg tcttgtaagc atattgaaat taaatccgct gtactatgtt
    18481 gttcaaggtt atcgtgagtc atttttaagt gaagcttggt tctgggagca tggaacatat
    18541 actttgtatt tctgggtttt cacgttagta atgttcgtaa tcggctctgc agtgttccgt
    18601 agattgaaac cacatttttc agatgtgctg taaggagaat agctatgaca gaatatgcaa
    18661 ttagactaaa agatatcaca aaatcttata atatgtacgc aaaaccttcg gatcgatttc
    18721 gtgaagccct caatcctttt aagaaatcct atcatgatgt attttatgcg ttgaaaaacg
    18781 tgaatgtaga aataaaaaaa ggtgagatga tcggtttcgt gggagaaaac ggatcgggaa
    18841 aatctacaat gttgaaaatc attacgggag tactgacacc aacatccggc acgatggaaa
    18901 tcgaaggaaa aatctcagct ttgctagaac taggatcagg attcaatcct gagtattctg
    18961 gctatgaaaa tatctattta aatggaatgg ttctaggatt ttcaagagaa gaagtcgatg
    19021 aaatggtcga tgatatcatt gaatttgctg acatcggcga ccatatttat caacctgtaa
    19081 aaacctattc aagtgggatg ttcgttcgtc tagcttttgc tgtagcgatc aatgtgaatc
    19141 ctgatatttt gattgtggat gaagcattgg cagtaggaga tcttgaattt caactaaaat
    19201 gtatggaaaa atttacagaa atcaagaact cgggaaagac gattttattc gtttctcatg
    19261 atattagttc gattcgccgt ttttgtgatc gttcctattg gttgaaaaat ggaaaagttg
    19321 tcgaatatgg tgatacgatg gaagtaacga cgaattacga aaactttttg aagaaaaaat
    19381 cagttaaaac agtagatcga aataaaaacc aagtagaacg cttcgcagct ccagatatcg
    19441 tagacgtgac gaaagccgaa ttgttggata aagataaaaa tccagtggat atgctggaac
    19501 aaggagaaaa actatacgtt aaagtaacct atgaagtaaa agacgataca atcaaaaatc
    19561 cagttttagg aattgctctg cgtacagtcg acaattttta tgtgtgcgga ctcaatactc
    19621 tactagatgg tatcaagatc ccttggaaaa aaggtgagaa tatcttttat ctggagtatg
    19681 aaaagttagg tttgttagct ggtgaatatt attttgacgt tgcggtcttt gaagaaaatg
    19741 caacggttcc tttggtatac aagacaaaat acatgaactt gtttgtcagc ggttcttata
    19801 tcggagaagg catcgtggtc ttagaccata aatgggaaga agggactcat agcaatgaaa
    19861 tatgattttg aaatggacct agatgaacaa agcagtgtgg gaaaaattgc cgcacagatc
    19921 aaaccaggaa gtaaagtttt agagtttggt cctggaaacg gccgattaac gaaacatttg
    19981 atcggagcaa aacaatgtga agtgagcatt gtcgagctag ataaggaatt gttcgatttt
    20041 gtcagcgagt ttgcccaaga tggattttat ggagatatcg aaagttttga atgggcaaac
    20101 tattatgctg gacaaacatt tgattacgtt ttgtttgccg atgttttaga acatttggta
    20161 gatcctggaa aaacgttgaa gaaagttaga gaatttttga atgaagaagg agaaattcta
    20221 attacattcc ctaaccttgc gcataattct gtcatgattg atttgttcaa taatcaattg
    20281 ccatgggctt cttatggttt gctagatgaa acccataatt ctttttatac tcatgatggc
    20341 ttccaaaaag tttttgaaaa agcaggatta tacatcaata ttgaagatta tttgtactta
    20401 gctgtaggtg atacagaatt aaaatcaact tatgaagaat tgccggaagc tgtacgttat
    20461 gatttcaaaa tgcgaccatt tggcgaagtc taccaatact tcttctcatt gatgaaacat
    20521 ccagtagcac aaagttccat tgcgcagccg caaaattcta attatgtgaa agtattagaa
    20581 gtaatccagc aaacgaaaca agatgaaata attcaacaaa taccattcaa taatttcaca
    20641 ggggaaaatg agacactaag tttccatgta tcagaattag cagaacgaat ggtgtttcgc
    20701 ttcgcgcagc aacctagctt tatcgaattc agcgcagaag ctgctggaga aaaactcaca
    20761 tttatcgatt caaatgctgt agtcaaaaca gtaaatgatt gttatttgtt tgatggtaaa
    20821 gatttaccag agttcttttt aacggatatt gcagggaaag aagtgactat ccattgtcac
    20881 tatcgtttta tcggagaatt gacaccaaca atgaaagaat tgctggaaac aatccgtcca
    20941 atggctgaag ttacaaagca gctttctgag aaaaatgatg aattagaaag agaaaatcat
    21001 tatcttattg agaataatac aagattagat cagacgttga aaacaaccat aaatcgctat
    21061 tgcacgttgt tggaaagtga tgaatggaca atcaaacata gattagggcg acgtaagaaa
    21121 gaaacatcga aaaaaatcca agaaaaagag ctttctctat gtattgacga aaaaatctgg
    21181 gatgcagaaa caaagatatt gaaaatcatc gggtggggaa tcgctaattc ggatcgccaa
    21241 ccattgtcct ataagttatc agccgaccaa tcaccatttt ttgaagcaat tcctgtttta
    21301 cgagaagaag tcaatcaagc aaaacagcta gctgaaggag caaaagcagg atttgaactg
    21361 cggatccttt gcgagaagga acgttcattc ttagttgaag cagtggctca aaatggtcaa
    21421 tcatggatca ttgaaatgta aataatgatt aacttataaa gataaggagt aaacgaatcg
    21481 tgcaaaaaaa agaaattgcc gtatttatcg atcaaatcac tcgtgaacgg gccactggcg
    21541 atttgcttat tgtgggctgg gcaattgatg aagtgaccaa agaaatccct acgataaagg
    21601 tagaaaaaga aaatgtgatt gctgaagcaa cacatgtcgt aagattggat atcaatcatt
    21661 tatataatct tgatgttaag acccaaagcg gttttaaggt acgtttatca gggaaaatga
    21721 gaggaaaagc aatcttagac ttccaaacag caagacatca aaatggcata gctgtgaaat
    21781 taaacggtaa atatccttat gatgacggca ttgaatcttc atgggaaaga aaaaaaagat
    21841 tactgaaaaa agggataaat tatgcaagga ctcatggcgt aaaaaaagca atccgccggg
    21901 tcaaactgga attgaaacca ggatcgatcg actatgcaga gtggatcagt cgtcatgaga
    21961 aacctgatct gaaagagcaa aggaaagaag tacaaggatt tgcctaccgc ccattgattt
    22021 ccatacttat gcctgtctat aacgttgaaa tcaaatggct cgaaaaatgc attgattcgg
    22081 tacttgatca aacgtatgat cactgggaac tatgtatcag tgatgatgct tctactgatc
    22141 cagctatccg aaagtgtcta gaatcctatc aagcaaaaga tgatagaatt aaagtcgttt
    22201 tccgacaaga aaatggacac atcagcctgg caactaattc tgcattggaa atggcagaag
    22261 gagagtttat agcgctctta gataatgatg acgaattacc tccatttgcc ttatatgaag
    22321 tggcaaaagt gctaaacgta catccagaac tggatttgat ctacagtgac gaagataaaa
    22381 tcgatgcaga tgggaatcgc tttgacccgc acttcaaagc agactggtct cccgatacat
    22441 tgatgggaaa taattatatc tctcacttag gcgtatatcg gacaagcatt gttaaggaac
    22501 ttggcggttt ccgtaaagga tatgaaggct ctcaagatta tgatttggtt cttcgtgtga
    22561 cagaacaaat tcctgcagaa cacatttacc acattgaccg tgtcttgtat cattggcgga
    22621 cgatcccggg atcaactgca agcaatggag aagctaaaag ctacatctat gattctggag
    22681 tgaaagcatt gacagatgct ctatctagaa gaaatatcaa gggaagcgta catcctggca
    22741 gaatttctgg tttttatgaa atcacttatg atgttttgca agaagacttg gtcagtgtga
    22801 tcattccaac taagaatggc tatgaagatc taaaaacttg tgtggattcg atcatcgaaa
    22861 aaacgtctta tccaaattat gaaatcatta ttgcagataa tggaagtaca gatcctaaaa
    22921 tgcaagaatt atttgcagaa tacaagcatc agctgaaaga ccgatttatc gtcgaattaa
    22981 ttgacattcc attcaattat tcacgtatca acaatctggc agcagaaaaa gcaaacggca
    23041 aatacttttt attcttgaat aacgatacag aagtgattga acctgactgg atgacagcga
    23101 tggtttctta tgcacagttt gatcgaatcg gctgtgtagg agcaaaactg ttttatccag
    23161 atgatacaac gcagcatgca ggagtattat taggaatcgg tggtgttgca gggcatgcat
    23221 tgaataacta tgatcgaaca cattgtggtt atttcggccg attggtcatt gacgtcaatt
    23281 acttagcagt cactgcagct tgtatgatgg tcaaggcagc tgacttcaat gctgttaacg
    23341 ggtttgatga aacattagaa gtagcattca acgatgttga cttgtgcttg aaagtttatg
    23401 aactgggtcg ttacaatgtc tatgcacatc aagcagaatt gtaccatttc gaatctaaat
    23461 caagaggtta tgaagatact ccagaaaaac aaagacgttt tgctggtgaa atcaaaaaaa
    23521 tgcaagataa atggccagca tatattgcgc atgatccatt ttacaatgat aatttaacaa
    23581 aagaaggaat cggcgacttt tcgttgagac cagattaaac tataataaaa agctgttatg
    23641 ttgtgattcg ctcgcacata acggcttttt atagtttttt gtcaaaaaaa ggcagaaggt
    23701 gccgactcaa aaaaataagt cgaggttggg acagaagtgt ttaactccga gaaataagaa
    23761 gaaattcacg aaaattgctt ttcaaatttt tgtgaatttc ggcttattta agaagaagtt
    23821 gcttctgctc ccaccgttta ttcgttttta aagaatgaga caaaagtgtt tcttactttt
    23881 gtcccacgct cttattcatg ctcagagcgc caatagatac aaaatcatag ccaaagtttc
    23941 acgaacccta gctgtcaaag aatcgatatt ttattttaat ataggctatt ttaaaataaa
    24001 tggtttaagg tattcctcta caaaagccac tctatcaatt atcatgggtt taaaataaga
    24061 agtgatggag ataaccagat tgttcttagc gtcaatataa agaacatttc cactattacc
    24121 aattgctgaa tatatttcgt tctcagaatc taatacccac cataaatagc catatctcat
    24181 attttgtaag tcttctaaag cactggttct aggtttgaac atctcgttta tccacatggg
    24241 tggtacgatt tgttttcctt tatacatccc tttatttagg cataatacac caatttttgc
    24301 cagatcactt gccgataaac acaaaccata tcctgccgtc ccgatattta gtggatcaca
    24361 aaaccagaca ttggttttag gagacttatc cattgtaaac tgcttatgtt cttcagctgt
    24421 ttcagcataa taattgacat ggtttggtat ccctatagga tcaaatagat acttattggc
    24481 aaaatcaaca gttgttagct tacttgtctg atacaacaag ccagttaata tgtgtaaaca
    24541 gacagtttga tagttgaatt cgccggttat accttttctt cctcccaata aatctagtga
    24601 tgtttttgtc caatcttcac ttgaacagac ttttgtccat ggatcgcctt tacatttgta
    24661 gggtgctttc attgttagca agtgcttgat tgtaatagcg taaatagttt tctccccgcg
    24721 tttcacttta tactctggaa aataatctaa tactttatca tcgatacttt tgattaatcc
    24781 ttgctctaaa gcaatgccaa tcagcaaaga tacaatactt ttcgttgctg acatgatatg
    24841 acaagtatcg tcttttttat aaccattcca ttcatctgta taaacttcta ccccatcctt
    24901 atatgcgaca atttgacata tatttggttg tcgaaaacca ataaaatcat gcaactcttg
    24961 tttattcata agatattacc tcactttctt ctataagcat aatgtcatta aaaatcgatt
    25021 tcaatttttt cgattcttca cgtaatacag gtattcttat ggactagaca gcgctttggg
    25081 aagatggatt ctctgaaaaa tataaaggtt cactttatga gtggataaaa aaagcagcaa
    25141 atacttcgac ttctttaatt taccaacatt agtgaaaatc gattcatctg gagatttgta
    25201 atttagagtc cttgtcttga ttagaggtgt ataaagcttt ttattagaca tttttaaatt
    25261 ccattacaat ttgcttataa actaggtttt taaaggtgac tatggtaaga taatagagat
    25321 attattttgt gattaggagt gtatatatga ataaaaatgg agaatggagt gctgcacgac
    25381 ggatattcat tatattaatg gatgttattg tatacaatgc agcaatatat agtagtttct
    25441 tactgaagtt tcgtggagag atcccattac gaaatttaga aactttccaa cactcagcaa
    25501 ttattatttc agtgattttt attgcgttga acattttgtt gggtgcatat gttttttata
    25561 atcgaatgat cagtgacatc gtgtttgtca cagtcatcgg tcaggtattg atgacactag
    25621 ggatcatggt agtgactttt gcgggccgct ggtttgcttt tccacgtctt gttatcttac
    25681 tttcatttgt tctcggtacg cttttcttaa gtatctatcg tattctcgta tataaacttt
    25741 atttacgcgt aagtcgagat aaaaaggtcg tcattattgg gttagaaaag gatgtcgcac
    25801 cagcaatcca aaattttggt tcaaagaaaa acaacaaaca taaagtcgaa gcagtcattc
    25861 ttgataacta ttatgcaaac atcaaaaata tgattaaaga catcgatatt gtctatcttg
    25921 cttctcatat cgaagaaact gaaaaaatca aaatctatca attagttact aaaaatgaaa
    25981 aaaaattgtt tttgaataca acatttgaaa acttgacatt gatcaatcca aatattatga
    26041 atttcgaaga tgaaagtatt attgaagcat ctggatttag aatccaacct gaatatgaac
    26101 tattcaaacg tttgtttgat atcatcgttt cacttgtttt attagttatt gcttcaccat
    26161 ttatgttatt cacagcaatt ttagtcaaag tgacatcacc gggaccaatc atctataaac
    26221 aagtgcggat cacaaaaaat caaaaggaat tttcaatcta taaattccgc tcgatgaccg
    26281 ccacagccga agcaaaatct ggaccagttt tagctaagag caatgatgca cgagtaacgc
    26341 ctgtaggtaa atttattcga gctgtccgct ttgatgaatt accacaaatc ttcaatgtgc
    26401 tgaaaggcga tatgtcgatc gtaggaccac gtcctgaacg tcctttcttc gtcgatcagt
    26461 tcaatgcaga aaacccttat tactacttac ggcataatgt tcgtgctggt atcactgggt
    26521 atgcacaagt ctatggaaaa tatgtctctg attacaacag taaattacgt tttgatttac
    26581 tttatatcaa aaaatattca ttgatgcttg atttaaagat cttgctgcaa accatcaaga
    26641 tcctatttga taaaatgtcc tctcaaggac ttgaagaaga cgaaaatgtg atctcattgg
    26701 cagaaattgc ttttccgaat gaaaaaatct ttcgctagtt gggaggcgta aaaatgaaca
    26761 atccgaaatt cagcataatc gtaccagtat acaatgcaga agcaactatt ggtcgaaaga
    26821 ttgatattct aaaagaattg gattatgaag agtacgaagt cgttttagta aatgatggat
    26881 caacagatca aacacaggaa atcattcaag aactgattga aaatgatgaa cgttttgaat
    26941 tgattactac gaccaatcaa gggcccggat tagcaagaaa cgaaggaata agacagtcaa
    27001 aaggagaata tctcttattc ttcgatgcag atgacacgcc agtaaaaacg atcttgtcag
    27061 attatgatca tttgctagaa aagagtccaa aagcggatct tgttgttagt tcgtttgttt
    27121 ttcgtacaat ggacgaggga agaatcgttt ccgaaaaaga aaacttagtt acagaatgtc
    27181 actatctaac tcacgaagag tttataaaag acatgtatca gttaatgaat gaacagttga
    27241 tgtatgttgt atggaacaaa tgctatcgta gcgatattct gaaaaataac caaattctat
    27301 ttaaaactta taatagttgt gaggatcgaa tatttaactt acattattat gaatactgtc
    27361 atcaagtgat catgaaccca aaagtagaat atatttatga atttgaaggt gggaagggga
    27421 tcactaatca ataccgacct aacaagttcg aaacatttaa agaattctat tcattagcaa
    27481 atactgtaac agacgatatt aataaagacg gtatggcggc gcttctttta aaagggacaa
    27541 cttcagttat tttttctatt tatagtacct ctgcaagaac ttcaaaagag aagaaagacg
    27601 aagcaaagca gatattgagt gatccagtga tccgagaagc caagcaaatt gctaagacgg
    27661 attcttcagc aaaaaaaata acaaagttgc tttacaatat gccagctcca ctatttttat
    27721 ctgctgtaaa agttggaagc ttcgttgaag tgaaaatgcc agggttaatg gctgctttga
    27781 agcgagtata ttagttaatg gaggaaaata taatgaaaag aattttgcat tttcagggac
    27841 gaatgggttt aggtggagca gagtctttca tgatgaattt atatcgtaaa attgatcgta
    27901 caaactatca atttgatttt ttgatttatg aagattatgc agatgttcaa gactatcatt
    27961 cagagattga aagattagga ggccgtattt ttgttgtacc taatcctaag aaaaatattt
    28021 ttaaatattt aatagaagtg aataagttac taaaaaaaga atctttttct atagttcaca
    28081 atcaggttta ttttggcggg ggaattaatt tatggttagc caaaaagaat ggaatcagac
    28141 agagaattgc tcatagccat gcaactgaag atggaaaatc tcaaaatatt gtaatgaatg
    28201 tattgcgtaa atttttaacc aaattgttgt tacaaaatgc aacagactac cttgccgtta
    28261 gtcaagaagc tggtgaaagt ctgtttcaaa accatccctt tgagatagtt cataatggta
    28321 ttgatttaga gctttatagt aaaaattcag aagctaaggt taataagaga aaagaattgg
    28381 atatctcaat gagtactttt gttgtgggaa acattggacg attagagaaa caaaaaaatc
    28441 aatcttattt gttagagatt tttttagaaa tactaaaaat gaattctgat tcttacttga
    28501 ttttagtagg tgaagggtca cttagaaata aactgaaagc caaagcagta gaattggata
    28561 tagagaaaag agtaaaattt ttaggagaaa gaaacgatat tcccgagtta ttatctgtga
    28621 tggatgtttt tgtaatgcct tctctttatg aaggtctgcc aatggttgga ttagaagcac
    28681 aagcagcaaa attaaaatta gtcttagcag atactatttc caaagataca aagttaacaa
    28741 ataatgtgga ttttgtatca ttagatgaaa caccacaaga atgggcaaaa aaagtaataa
    28801 aagagccgta tgctaataaa ataacacaag aactaaagag ttatgatgtt tcgtacacta
    28861 ctgaacaaat ggagagtata tatagtagag atcattaaaa atgttcaaga tattttagga
    28921 gtgattattt ttgaaaatat gttatttgat attggcatac aatgatattg gcaacttaaa
    28981 gagattggtc aatcgattga acgaaaatgc agtttttatt attcatatag ataaaaaaac
    29041 tgatatagaa ccatttattg aagcatttaa atcatatgat aatgttgaat ttttatgtaa
    29101 taaaaaccgt gttaaaattt attggggtgg tttttccatt gtacaagcag aaatcaattt
    29161 agtaaagaga gcattacaaa atgagaaata tttaaaatat gtattattat ctggtgctga
    29221 ttatccaatc aaagataatg agtatattta taattatttt aaaaagaa
//
LOCUS       DAZULR010000033        28855 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.033, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000033 DAZULR010000000
VERSION     DAZULR010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28855
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.033"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            85..624
                     /locus_tag="ACG8ZV_001741"
     CDS             85..624
                     /locus_tag="ACG8ZV_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997080.1"
                     /translation="MWSLVGIVLIIFTVTAATEANYSHKIQSYKGRLVMTKKDVTRYT
                     SSRTGGLYDYAPLDALKYKDHLKKHEVKVGDRWENASHKAYNSKIVYTVEDADEQNIT
                     LPVFNYWGTVVKVNGKKSTIENDNGLVSIKGTGKRTIVEVSSTYPTTMILSLLISSIT
                     FIFLFTRYLIRCCGEMKID"
     gene            1644..2813
                     /locus_tag="ACG8ZV_001742"
     CDS             1644..2813
                     /locus_tag="ACG8ZV_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HFS4997081.1"
                     /translation="MPNFTTEIMETLINKGDLDELFRCHLELAVNSLLQAELTAFLDY
                     EKYDRAGFNSGNSRNGNYSRSFRTEYGELNLVIPRDRNGKFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMSEISELIEKMYGHHYTPQTISNMTKIVSEDIIAFKERSLESRYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFSLAPTESAYVWKEILQDLKDRG
                     LKEVLLVVTDGLSGINDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     YQASSKEEANNQIRFMIDKWKKQYPRVVKLLMNPAILTFYNFPPSIRRTIYSTNLIEG
                     FNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLESMF"
     gene            3286..3840
                     /locus_tag="ACG8ZV_001743"
     CDS             3286..3840
                     /locus_tag="ACG8ZV_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4997082.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGV"
     gene            complement(4013..4450)
                     /locus_tag="ACG8ZV_001744"
     CDS             complement(4013..4450)
                     /locus_tag="ACG8ZV_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4997083.1"
                     /translation="MFSSEENKPLYLDYVNHNLKIIIKENNLKHITLHGFRHTHCSLL
                     FESGASVKEVYVRLGHTDIKTTMDDIYTHIAKKQTEETAIRFADFMSSTEEKQGSLQK
                     VKSMVKNEKSRLSLLDSLLNVELSVFFLFRSVCVFETVLILFF"
     gene            4498..5445
                     /locus_tag="ACG8ZV_001745"
                     /pseudo
     CDS             4498..5445
                     /locus_tag="ACG8ZV_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016634498.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
     gene            5716..6151
                     /locus_tag="ACG8ZV_001746"
                     /pseudo
     CDS             5716..6151
                     /locus_tag="ACG8ZV_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345965.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit A"
     gene            6167..7000
                     /locus_tag="ACG8ZV_001747"
     CDS             6167..7000
                     /locus_tag="ACG8ZV_001747"
                     /inference="COORDINATES: protein motif:HMM:NF012742.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFS4997084.1"
                     /translation="MLYFSAIDNADFVFSDPFTAEVLSGIEEQAKNHGYFVLVHNVNS
                     AEDVKTIQRNWRFEGFIVVGVRVKEFLELNNVFDGPVVYIDTHLSKETLRELEQQMNR
                     LFVNTNDYQASTLAVEHLIHYGHEKIAFLSFDYIVGEPSVIQERHQAYIDTLKKYHLT
                     FKSHWIYNNSEFERIYQELAEFTAIVVTGDYLAAKLVKFLKNKNKRVMEQLSIIGFDD
                     ITFAELMDPALTTIRLNPGNKGAIAFHQLIGLAKQEEIKNQVLLLEGELISRDSVHKI
                     K"
     gene            7245..8270
                     /locus_tag="ACG8ZV_001748"
     CDS             7245..8270
                     /locus_tag="ACG8ZV_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFS4997085.1"
                     /translation="MVGIRDVAKRAGVSIATVSRVLNEDPTLSVTDETKRKIAESVNF
                     YHYVKKSPVAKNLTNIALITTVSEVDELEDPYFRTIRRGIQVEAEQSKVNLKKIIRLS
                     ETPLEQDDLLKCQGVLIIGQVLSSVIEEVSAINSNVVVIDDPSIEAEVDAVYTDLTKA
                     TNQHLDRLYKKGHRNIAFIGGGRVRLDSQGNKHVSDDDYRKIAYETWMKQKGLEKYSQ
                     IYLEGWTTLDGMQAADLLLKKHAKDKLPTAIMVGNDPIAVGVYRSLQKNGLHIPEDIS
                     IVSFDNIEVAEFLTPALNTVNVNTEEIGKLAVRMVNERIKEVRNVSIKVIVSNNIIVR
                     ESEKNID"
     gene            8408..8533
                     /locus_tag="ACG8ZV_001749"
     CDS             8408..8533
                     /locus_tag="ACG8ZV_001749"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997086.1"
                     /translation="MKHFKKIALTGIAVLTGTLLAACGGGDSNSKDGQVTLSYAS"
     gene            8558..9673
                     /locus_tag="ACG8ZV_001750"
                     /pseudo
     CDS             8558..9673
                     /locus_tag="ACG8ZV_001750"
                     /inference="COORDINATES: protein motif:HMM:NF024808.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
     gene            9756..10652
                     /locus_tag="ACG8ZV_001751"
                     /pseudo
     CDS             9756..10652
                     /locus_tag="ACG8ZV_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338086.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
     gene            10668..11492
                     /locus_tag="ACG8ZV_001752"
     CDS             10668..11492
                     /locus_tag="ACG8ZV_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4997087.1"
                     /translation="MKNKFFSNAPIHIMLILGGIAMALPFIWMILTSGKTLVESTQIP
                     PTIFPEKFQLSNYQQVLDLLPFMAFYINTFLMVVGRVIGSVLFSAMAAYACARLSFPG
                     KNILFSLVLIQMMIPGSIFITPQYLLAQKLGILNTIPALILPGVVSAFGTFLLRQFFL
                     GLPDELEEAAYLEGANIWTIFFKIMLPLAKSGLVALGIFTALFAFKDLMWPLIVNTSI
                     DKMPLAPGLANLQGQYATNFPQLMAGSLLAIWPIVVIFIVFQRKFIEGIATTGSKL"
     gene            11524..12834
                     /locus_tag="ACG8ZV_001753"
     CDS             11524..12834
                     /locus_tag="ACG8ZV_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005235059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase/alpha-galactosidase"
                     /protein_id="HFS4997088.1"
                     /translation="MTKITFIGAGSTIFAKNVLGDAMLTPSLQDAHIALYDIDEKRLK
                     ESNLMLKNINKNSNENRADIVSYYDRKEALREADFVINAIQVGGYKPSTVIDFDIPKK
                     YGLRQTIGDTMGIGGIFRTLRTLPVMLDFAKEMEEVCPNAWLLNYTNPMAMLTMGVLK
                     ATSIKTVGLCHSVQVCVPELFEHLGIADQYDLNDFQWKIAGINHMAFLLEITKNGEDF
                     YPTIRQLAAEKPNPHPDSVRFELLKRFGYYITESSEHNAEYHPYFIKSKYPELIDELG
                     IPLDEYLRRCEQQINDWESMREDIVNNGELTHTRSREYASYIMDSITTGTPSVIAGNV
                     LNKGLITNLPTDVCVEVPCLVDKNGVQPTYVGELPTQLAALNRTNINVQELTVEAALT
                     LDKSKIYQAAYLDPHLSSELSLTDIKNLVDDLIEAHGDYLPEYN"
     gene            12982..14241
                     /locus_tag="ACG8ZV_001754"
     CDS             12982..14241
                     /locus_tag="ACG8ZV_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFS4997089.1"
                     /translation="MKWSKKIILACIALGATISLTACGKNQEDASGKVEIEFFNQKKE
                     MTQTIQEIAKDFEAKNPDIHVKVVDVPNAGEVIKTRMLAGDVPDVINLYPQSIELKEW
                     AKAGYLEDLTEEPYLENIKNGYAQRFAIEDRVYSIPLTANVYGFYYNKTAFEEMGIQA
                     PETWAEFEKIVAEIKDQNKVPFAIAGAEGWTLNGYHQLAIATAAGGEEEANNVWRFSE
                     VNGINAESKEMQKDFNRLDLLREPKALQNNWQGAGYNDTVVTFTKGDALIMPNGSWAM
                     PMIHSQNPDFEVGTFPFPADEAGQSLTIGAGDLALSVSATSQHKEEAKRFVEYMTTPE
                     AMQKYYDVDGAPCAVEGVIENTQDSPLSGLTELAFTDRHLVWLAKDWNSENDFYTLTT
                     NYLHNGNQKAMINALNAFFNPMKADGR"
     gene            14251..15123
                     /locus_tag="ACG8ZV_001755"
     CDS             14251..15123
                     /locus_tag="ACG8ZV_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4997090.1"
                     /translation="MKIKEILNRYWAIIFVAIPIILQMIFFYFPMVQGAFYSLTNWTG
                     LTYNFDFVGLNNYKILFSDPKFIKSIGFTLIVTLCMIAGQIGFGILIARALNANIKGK
                     TFFRAWFFFPAVLSGVVVSLVFKQIFNYGLPKIGSMLGIEFLQTSLLGTTWGAIFAVI
                     FVLLWQGIAMPVIIFLAGFQSIPQEIIEAARMDGANDKQIFWNIEITYLLPSISMVFI
                     MALKGGLTAFDQIFALTGGGPSDATTSLGLLVYNYAFKNNQFGYANAIALVLFILIGI
                     VSLAQLKLSKKFEI"
     gene            15135..15965
                     /locus_tag="ACG8ZV_001756"
     CDS             15135..15965
                     /locus_tag="ACG8ZV_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4997091.1"
                     /translation="MKTSKEKNISKYLLLLLGGFMILVPLVSTLFGSFKTTPDIMNNF
                     FRFPNPATLENFRRLLADGIGHYFWNSAIITIIAVVAVTAIIPMAAYSLARKMTRGKA
                     YGLMYLFLILGIFVPFQVIMIPITVMMSKIGLANMWGLILLYLTYAVPQTLFLYVGFI
                     KLNVPISLDEAAEIDGASHFTTYFKIVFPMLKPMHATTIILNALWFWNDFMLPLLILN
                     RDSNMWTLPLFQYNYTGQYFNDYGPSFASYTVGIVTITLVYLAFQRSIIAGMSNGAVK
                     "
     gene            16005..18188
                     /locus_tag="ACG8ZV_001757"
     CDS             16005..18188
                     /locus_tag="ACG8ZV_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HFS4997092.1"
                     /translation="MIIFDNHTQTFHLQNKKISYLLGIEENNYLTHLYFGKKITHYSG
                     GYRYPRTDRSFSPNNANAQDRLLSLDTLPLEFPGYGHGDFREPAHNIKLGNGSRVNDF
                     RYDSYEIQKGKPSLAGLPALYTEDDDEAETLIIQLKDAISGLTLQLFYTIYQNHSVII
                     RSTQLVNNSDETVEINRLASQSIDFPNRPLELIHLNGTWARERQMTREKIHTGIKVLD
                     SKRGSSSHQQNPFVALVDAKTDEFQGEAYGFNLVYSGNHETVIQKDPFDQTRVIMGIN
                     SFNFGWQLKTGDSFQTPEVVMVYSNEGLNTLSQTYHELYNHRLIRGNYRLKERPTLIN
                     NWEATYFDFNEEKIMNIVDDAKNLGIEMFVLDDGWFGGRENDFTSLGDWVETEGKLAC
                     GLENLAKQVHDNGMKFGIWFEPEMISEDSELFRAHPDWALGIPGRDRSISRNQYVLDF
                     SRQDVRDNIYQQMTAIFDRVPIDYVKWDMNRNMTEVYSVLLDSTMQGEVAHRYMLGLY
                     EFLEKLTTNYPTILFESCSGGGGRFDAGFLYYMPQTWTSDNTDAVARLKIQYGTSLVY
                     PISSMGAHVSAVPNHQTGRETSLTIRGNAAMAGVFGYELDLTQLTSEEKAEIKEQVAF
                     YKKHRQLLQYGTFYRLESPFEGNDTAWMFVSKDQTEAMVFYFRVLAEAAHPLVTLKLA
                     GLAEEATYQMEDVTFAGDELMNLGFYIDSELHGDYATQRFYLKQI"
     gene            18249..19469
                     /locus_tag="ACG8ZV_001758"
     CDS             18249..19469
                     /locus_tag="ACG8ZV_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HFS4997093.1"
                     /translation="MFYLHAFTKKQPDLNWENEEVREEIYAMINYWLDKGLGGFRIDA
                     ILNIKKKLEYGIFESDGEDGLAFIGPWILNQSGIEVWLKEMRERTFKPHNSMTVAEAD
                     VPNERLDEYIGEDGYYSMVFDFSYTDIDVPETGEWFKDSQWTWTDMRTNIFTNQLVTQ
                     DKGWGALYLENHDQPRSINKYIPEEWINDYSKKMLATLFMLLRGTPFIYQGQELGMTN
                     IEMASLEDFDDVATHSQYKRALEYGLAPEQALKAVNKRSRDNSRTPMQWNTQKNARFS
                     TSDNVWLKVNPNYPELNAEAQLTNQQSVFNYYHQLIKLRKNSVYKDVLIYGQFLPVKD
                     KNEHILLYERQLEDKIVLVILNVTATEQEYYVDEQYQQVLINNYEDVLLDQSRKLRLR
                     PFESIVLANYGGQL"
     gene            19466..20926
                     /gene="gtfA"
                     /locus_tag="ACG8ZV_001759"
     CDS             19466..20926
                     /gene="gtfA"
                     /locus_tag="ACG8ZV_001759"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HFS4997094.1"
                     /translation="MKIKNEAMLITYADSLGKNMGELKQVLDKHLQGVIGGVHLLPFF
                     PSTGDRGFAPSDYTTVDPALGTWEDVEALGEDYYLMFDFMINHISRESKFFQDFKKNH
                     EQSPYKEMFIRIHEFFPENRPTQEDIDLIYKRKDKAPFQTVEFADGTTEEVWNTFGEE
                     QIDLDVTKEVVKEFIRETIKDMANHGCSLIRLDAFAYAIKKLDTNDFFVEPDIWELLD
                     EVRQEAAKYDVELLPEIHEHYSIQMKIANHDYYIYDFALPMVTLYSLYSGKSERLANW
                     LKMSPMKQFTTLDTHDGIGVVDARDLLTDEELDYTSEELYKVGANVKKVYSSANYNNL
                     DIYQINSTYYSALGDNDRSYLLARAIQVFAPGIPQIYYVGLLAGKNDIELLEATKEGR
                     NINRHYYDLAEIEEEVQRPVIQQLFALLKFRNESAAFDLDGTIEVATPSESEIVITRK
                     NKNGSDSATLTANLDTKEFIIESKDIKIFTSVALKF"
     gene            21003..22109
                     /locus_tag="ACG8ZV_001760"
                     /pseudo
     CDS             21003..22109
                     /locus_tag="ACG8ZV_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175341.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            22431..22640
                     /locus_tag="ACG8ZV_001761"
     CDS             22431..22640
                     /locus_tag="ACG8ZV_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HFS4997095.1"
                     /translation="MVVITKNELMKLGYGKYQSERIIRQAKAIMVSKSYTYYENRRLG
                     LVPVESVEEVLGMKIEVEEDFQNHG"
     gene            22633..22782
                     /locus_tag="ACG8ZV_001762"
     CDS             22633..22782
                     /locus_tag="ACG8ZV_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HFS4997096.1"
                     /translation="MVNFKKDKNGKYHFTASLGFDKRTGKRVQKNVEGLKQLKKKKSV
                     YRTCF"
     gene            22936..23601
                     /locus_tag="ACG8ZV_001763"
     CDS             22936..23601
                     /locus_tag="ACG8ZV_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4997097.1"
                     /translation="MELREIRPIDIQKWQNNLLSKYKNSYVRNMYGIFQMSLDRAVVL
                     GLLEKNPAKVIGNVKKRKTTVDFWTKEEFTKVISTFYIDDLYQHFGFICMWLLFMTVM
                     RLGEATALTWKDIDFENKNLRVNKTLYYKRAKTYEFVEPETASSIRTIELDDNTITFL
                     KAWKERQVSIGGMSFVLSYNGTPTQKYTIRHIMRRHATIVGVHIIRIHGLRHSHASLL
                     ISQ"
     gene            complement(23885..24970)
                     /gene="xerS"
                     /locus_tag="ACG8ZV_001764"
     CDS             complement(23885..24970)
                     /gene="xerS"
                     /locus_tag="ACG8ZV_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HFS4997098.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLDNNPMDQVATITDKTTLAARAN
                     AIEKKLFLDKDTQNYLDYIANEYKNTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VININLDDLSLDKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRIQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHSSTNTTTLYTHIDNAATIDALNAL"
     gene            25304..25537
                     /locus_tag="ACG8ZV_001765"
     CDS             25304..25537
                     /locus_tag="ACG8ZV_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HFS4997099.1"
                     /translation="MAIKERKFREVGNSVVLTISKEFLKENGLNPGDTVFLDEEKLRA
                     AITKKQALSDEIDLAISQALTEYDTTFRELVDK"
     gene            25534..25941
                     /locus_tag="ACG8ZV_001766"
     CDS             25534..25941
                     /locus_tag="ACG8ZV_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HFS4997100.1"
                     /translation="MSIHYLEAKDIIKMNVIQIKKYSPNEPLGVKDANALEMCVGQLR
                     ASAFGEEVYPSIYEKAAILLIQLIKKHPFHNANKRTAFLATFVFLKINGQLLAIDQKD
                     AVNLAVYIATYDKDFDQLKYEVINTIKTHTQPI"
     gene            complement(27078..27596)
                     /locus_tag="ACG8ZV_001767"
     CDS             complement(27078..27596)
                     /locus_tag="ACG8ZV_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HFS4997101.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
     gene            27963..28211
                     /locus_tag="ACG8ZV_001768"
     CDS             27963..28211
                     /locus_tag="ACG8ZV_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997102.1"
                     /translation="MVKLKMLYIGLQHRSFFDCALGKKYYEVKIDDDTFLTAHQMKQL
                     QKRNDQLEENLILKKRLPYSRLARRTIKGQDLPEDHPF"
     gene            28714..>28855
                     /locus_tag="ACG8ZV_001769"
     CDS             28714..>28855
                     /locus_tag="ACG8ZV_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFS4997103.1"
                     /translation="MSKRTRRTFSQEFKQQIVNLYLAGKPRVEIIREYELTASAFDKW
                     VKQ"
BASE COUNT         9930 a         4349 c         5289 g         9287 t
ORIGIN      
        1 agaaccttgg gttttcaagt gctttttggt tcattaatct taaccatagt gtttttaaag
       61 tggaaaacaa gcaacaaaaa aagtatgtgg agccttgtag gaatagttct tattattttt
      121 actgtgactg cagcaacaga agcaaattat tcgcataaaa ttcagtcgta taaaggtcgt
      181 ttagttatga ccaaaaaaga tgttacacgt tatacatcct caagaactgg aggcctatat
      241 gactatgcac cattagatgc attgaaatat aaagatcatt taaagaaaca tgaagtaaaa
      301 gttggtgatc ggtgggagaa tgcatctcat aaagcatata attccaaaat agtctataca
      361 gtagaagatg ccgatgagca aaatatcaca ttacctgtat tcaattattg gggaacagtt
      421 gtgaaagtaa atgggaaaaa gagcactata gaaaatgaca atggtttagt gtctattaaa
      481 ggtacgggga aaagaactat agttgaggtt tcatctacgt atccaactac gatgattcta
      541 tctttattaa ttagttcaat aacttttata ttcttattta cacgttattt aataagatgc
      601 tgcggtgaaa tgaaaataga ttagatagat attataaata tgttgattct attttcatag
      661 caatggagaa aatacattag caatatataa aagaaggtat caagagtcac agtgaattta
      721 ttccgaaaag tgaaaagagc aaatataaaa tttaatgaaa atatagaact aaataggaaa
      781 acgtagacgt aattttctac gttttccttt tcatatatat taaatattac ggaaaattat
      841 ataaactaat ttagtgtttt gtttgtaatt cctaattttg ctccactttt agataatttt
      901 taggtctatt taactcatca gacattctat gctcattttt ctccaaattt gtttcaactc
      961 tttcgtactt aattttgcgt atttgaaaat tcttctttta gagtactttt attacgatac
     1021 tagtatgata tatatctata gcaaacagtt aaaatcttcc taaaataagc gaatagcatt
     1081 cctaaaacct ataaaatttt tagatgaagc gacaagtgga caattaataa actacttgaa
     1141 catgaaatta tggatcacct ttcaaattta gaaaatggaa ttcttatact tattgcgcaa
     1201 catttattga ttgcaaaatt atgtgacaaa aaaaactagt agaagaaaga ataatggctt
     1261 gataataaag tactacctat taaaggtagt actttattta atttagtata aattaacata
     1321 ctactatatt ttaggtttca tattatataa attaataata tactaccatt tgttggtagt
     1381 ataatttaaa ggtaataagt tattctttta ttactatgtt tgggttttat agcaaagaaa
     1441 gtttaataag agtttggacc tagcaaacaa tattaatgag gtcattaaat cttattatct
     1501 ttagtgatat aacgaaatat ctacacagac aaaatgatag cgtaaaatat tttgtgtaaa
     1561 tagatattta gggtagaaaa aaagaaagtc cattctgtaa aattaaagtt accacaaccg
     1621 aaattttata ggaggacttt ctcatgccca attttactac agaaattatg gaaacactaa
     1681 tcaataaagg tgatttagat gaattatttc gatgtcattt agaattagct gttaattcat
     1741 tattgcaggc tgaattaaca gcttttcttg attatgaaaa atatgatcgt gctgggttca
     1801 attcaggtaa ttcccgtaat gggaattatt cacgttcatt cagaacagag tatggagaat
     1861 taaatttggt aattcctaga gatagaaatg gtaagttttc tcaacaaact ttacctgctt
     1921 ataaaagaac caatgactct ttagaaacca ctattattca gctatttcaa aaaggaatta
     1981 ctatgtctga aatctctgaa ttgattgaaa aaatgtacgg gcatcactat acgccacaaa
     2041 ccatttcaaa tatgactaaa atagtttctg aagatattat tgcctttaaa gaaaggtcct
     2101 tagaatccag atactctgtc atttttatgg atgctactca cattccttta aaaagacaaa
     2161 ctgtttcaaa agaagcagtt tatattgtaa ttggcattcg attagatgga accaaagagg
     2221 ttcttgggtt tagtcttgct ccaactgaat ctgcttatgt ttggaaagag attcttcaag
     2281 acctaaaaga ccgtggttta aaagaggttt tattagtcgt aactgatggt ttaagtggca
     2341 ttaacgatag tattcatagt gtttatccaa atgctcaatt tcaacaatgt tgtgtccata
     2401 tatctagaaa tatcgctcat aaggttcgtg ttagtgatcg acaagaaatc tgtagcgatt
     2461 tcaaattagt ttatcaagca agttcaaaag aagaagcaaa taatcaaata aggtttatga
     2521 tagataaatg gaaaaagcag tatccacgag tggttaaatt gctcatgaat cctgctatat
     2581 taacctttta taatttccct ccgtcaatca gaagaactat ttattcaact aatttgattg
     2641 aaggttttaa caaacaatta aagaaatata ccaaaagaaa agagcaattt cctaatgaag
     2701 aatctctgga gagatttcta gtatctcaat tcaacaacta taatcaaaag tttctatgcc
     2761 gagttcataa aggttttaaa gaaatacatg atacattaga atcaatgttt taacttgatc
     2821 aacagaatgg gcttttccat ttacacaaaa ttattgacgc tcccgacaaa attatgatct
     2881 tgcgtaaagt tataaaatat taataaaaat attttattaa tgaaaagctt ggtagcacgg
     2941 ttattcatat gctaatttat ttcactttat agtaagggga gttcttagta tattgttcaa
     3001 acttaaattt catataattt aattatgtaa attagctatt ctaagaactt ctacggataa
     3061 ctgcccgtct aaaatttaaa taagagctta gaatcttcat ataagtaagg ttaatttttt
     3121 tgtacaaaaa agtcggaata ttctgagtta ctgaaatgat ataaaatcat aaactaaatc
     3181 ccttgatttt attgactttc aaaagtttat atatataagt taatgattat ggtaaaatat
     3241 atacataatc attaactcag aatattttta agaagggaaa caatagtgag ctataatgta
     3301 caaccgttaa ggacaaatga agagatacaa gattttcagt tttggctaag aagaacaagt
     3361 aatccggaaa gagatagttt tttatttttg tttggaatca ataatgggtt acgtatgtca
     3421 gatattatag gattaaaagt tggagatata cgaggcaaaa gtaagcctat tattgttgaa
     3481 cataaaacag gtaagcgaaa accgattttt atagataatt tgagagaaga aattttatta
     3541 tatactgaag gtaaagaaga aaatgattgg ttatttccga gtcggcaaca aggtcgacat
     3601 ataacaaggg atcgtgtcta tcagatatat gcagatatag cagaaaaatt aggacgagat
     3661 gatataggaa cacatacatt aagaaaaact tttgggtatc actactacaa gaaaactaga
     3721 gacattgcta ccttaatgtt tatttttaat catagctcgc aagcaattac aaaaaggtac
     3781 attggtataa ctgaagatga aataggagca tcacttcgtg gatttaaact aggtgtataa
     3841 tttaaaaatt tttataaaca gtaaagacaa agattaaaag ctatttttat ctagaacgat
     3901 tttatttcat aaagttcgcg gaataaaagc tggggttact ggtacttggt ataggttcgt
     3961 gttatataaa ctaagtaatt aaataacatt tttaggttgg aaaaggatga aattaaaaaa
     4021 agagaatcaa tacggtctca aaaacgcaaa cgctgcggaa taagaaaaat actgataact
     4081 caacgtttag cagactatct aatagggata gtctgctttt ttcgtttttg accatacttt
     4141 tgaccttctg caaacttcct tgcttttcct ctgtagaact catgaaatct gcaaaacgaa
     4201 ttgccgtttc ctctgtctgc tttttcgcga tatgggtgta tatatcatcc atagtggttt
     4261 taatatctgt atgtccaagt cgaacataca cttctttgac agacgcacca gattcaaaga
     4321 gcagactaca atgggtatga cgaaaaccat gaagtgtgat atgttttaag ttattctctt
     4381 taatgatgat tttcaaattg tgatttacat agtctaaata aaggggctta ttttcttctg
     4441 atgaaaacaa aagttgttca ccatctttta taggtttgat tctcattttt agatattatg
     4501 cccgcacgta ttcatcacat ttctattgtg aatcgcttta ttcgaccgac atttgacttt
     4561 tatcataata tactcggttt aaaattacta atgaaaacaa ttaatcaaga cgatcatacc
     4621 atgtatcacc tgtttttttc agataatcac caccgtgtgg gaactgaact gacttttttt
     4681 gaagtacaag aagggaacaa ccagtttttt ggaaccaata cgattgaacg aacgatacta
     4741 aaagttcctt ccgaagcatc attgcatttt tgggaaatat attttgaaac acaaggcgtt
     4801 tgccattatg gaatcgaatc attttctgga cgacctatct tacgttttga agggccagat
     4861 gcaacacgat tagctttagt tcccttacgc gaatttgaag atattgatga ttatttcccg
     4921 tatgtcacag accagatccc tacagagcat gccattttag gaattgatgc cattcaacta
     4981 cgcgtacaat attccgatgc gactgaacga gagttattgt cggtaggctg gtagcacaaa
     5041 gaatacgtca gtttcttttc gggtcatcaa cgagtgacaa tcttagaaaa tcaagacact
     5101 cagttctatc aagaagttca gattattcaa gatcgtgaga atccagttgc cattgaaggg
     5161 attggtagcg tccatcatgt tgcgtttggc gtagaaaata aatctgattt acaacgcatc
     5221 gacaaacaat tacaagagcg caattttata aattcaggaa taaaagatcg tgaatttttt
     5281 gtatcacttt attatcgtga cccaaatcaa ttattgattg aaattgctac aggggaagga
     5341 aacctagatg caaaagcgta tgaaaatcaa agtccacgct ttgaagaaat tcctttattt
     5401 ttaccgcagt acttaaattt cattcgtgaa caagtggagc aataattagc taatcaaatc
     5461 catgacgaag agtaagaggt tgactcataa gtcaaaaaat aaagaaaaac gcatcaaatc
     5521 cattctaaag aatgttgatt tgatgcggtt cctattttta taaactatca ttttcgacta
     5581 ataaaactac ttatgagtca gcctctcttt ttttcttgat ttttatacct ctttctaggt
     5641 aaactaaaca tctgccaaaa ataccgtgtc tcattgaaac attctcaact atttcaaaat
     5701 aaaggggagt accaaatgaa cgagtatatt gaaattatcc acgcaagaga aacaacttaa
     5761 aaatgtcagt ctcaaaattc ccaaaaataa aattagtatt tttaccagcg tatctggttc
     5821 aggaaaatca tcgattgttt ttgatactat tacccaagaa gctggtcgtc aactgaatga
     5881 cacctatgat agttttaccc gtttattttt acctaaatac agtcgtccag aggttgatga
     5941 gattgataat ctttctacgg cgattgtggt caatcaaaag aagattggtg gcagtgcgcg
     6001 ctcaacgtta gggacgatta ctaacatcaa tgcgttattt cgtgtgttgt tttcatgttt
     6061 tgcaacacct agtttaggat atgcaaatgc ttattcattt aatgatccta gtggaatgtg
     6121 ttctgtctgt cagggaatcg gtaagacgat tgcattttta ataggattgc tttatttttc
     6181 ggctattgat aatgctgatt ttgtattttc tgatccattt accgcagaag ttttgtctgg
     6241 aattgaggaa caggcaaaga atcatggtta ttttgtattg gtgcataatg ttaattcagc
     6301 agaagatgtt aaaactattc agagaaattg gcgttttgag gggttcattg ttgttggtgt
     6361 acgtgtaaaa gaatttttgg aattaaataa cgtttttgat ggtcctgttg tttatattga
     6421 tacgcatctt tcaaaagaga cattaagaga acttgaacaa caaatgaatc gtttatttgt
     6481 aaatacaaat gattaccaag ctagtacatt ggcagtggaa catttgattc attatggtca
     6541 tgagaaaata gcgtttcttt cttttgacta cattgtaggt gaaccaagtg ttattcaaga
     6601 acgacatcaa gcttatatcg atacattaaa gaaatatcat ttaaccttta aatcgcattg
     6661 gatatataac aactctgaat ttgagcgaat ttatcaagaa ttagctgaat ttactgcaat
     6721 tgttgttact ggagattatt tagcggctaa attagtaaaa tttttaaaaa ataagaataa
     6781 acgagtgatg gaacaattat cgattattgg atttgatgat attacttttg cagaattaat
     6841 ggatcctgcg ttgacaacaa tacgactaaa tccaggtaac aagggggcga ttgcttttca
     6901 ccaactgatt ggactggcca aacaagaaga aataaaaaat caagtactac tattagaggg
     6961 agaattgatt tctcgagact ctgttcacaa aatcaaataa aaaagctctg tgaaataagt
     7021 atagttaaca ataaaatatc cgaacgatag agagaatgaa ctgtgatcta gcagttcctc
     7081 gtcgcaaatt cactagaatt agcattattt actctaaatt gttcggatat tttttcttgt
     7141 ttttaattat gattacagtg cctattttta acgaaatttg cttattttca aaatgtatga
     7201 ttatatgtta gtaaacactt tcaaatatga aaagaggagc tattatggta ggaattaggg
     7261 atgttgcaaa acgggcgggt gtgtccattg caacagtatc gcgcgtgcta aatgaggatc
     7321 cgacactttc agtaaccgat gaaaccaaac gaaagattgc agaatcggtt aatttttatc
     7381 attatgtcaa aaaaagtccc gttgcaaaaa atttaacaaa tattgcatta ataacgacag
     7441 tttctgaagt agatgagttg gaagatccct attttcgaac gattcgcaga gggattcaag
     7501 tcgaagcaga acaaagcaaa gtcaatttga agaaaattat tcgtttgtca gaaacaccgt
     7561 tggagcaaga cgatttgcta aaatgtcaag gtgtgttgat tattgggcag gtgctatctt
     7621 ctgtgattga agaagtatca gcaattaatt cgaatgtcgt agtgattgat gaccctagta
     7681 ttgaagctga agtagatgca gtttatactg atttaacaaa agcaacgaat cagcatttag
     7741 atcgattgta taaaaaagga caccgaaaca ttgcgtttat cggaggagga cgtgttcgtt
     7801 tagatagcca aggaaataaa cacgtgtcag atgatgatta tcgaaaaata gcctatgaga
     7861 cgtggatgaa acaaaaagga ttagaaaaat atagtcaaat ttatttagaa ggctggacca
     7921 cacttgacgg aatgcaggca gcagatttac ttttgaaaaa acatgctaaa gataagttgc
     7981 cgactgctat catggtagga aatgatccta ttgctgtggg ggtttatcgt tcacttcaaa
     8041 aaaatggtct acatattcca gaagatattt cgattgtgag ttttgataat attgaagttg
     8101 ctgaattttt aacacctgca ttaaatacgg tgaatgtgaa tacagaagaa attggaaaac
     8161 tagcagttcg catggttaat gaacgaataa aagaagttag aaatgtttcg atcaaagtga
     8221 ttgtttctaa taatattatt gttagagaaa gtgaaaaaaa tatcgattaa aaaagtaaac
     8281 atccaaaaaa gggtgtttac ttttttgttt actaatattt ttagtaaaaa atctcgacaa
     8341 aacattaagt aaacagttat ggtgttgtta acaaaaagaa aacgcattca aaacaggagg
     8401 aattaagatg aaacatttca aaaaaatagc tttaacaggg atagctgttt taactgggac
     8461 attactcgca gcatgtggtg ggggagatag taattctaaa gacgggcaag taactttaag
     8521 ctatgcgagt tgagatactg accaagctcc aggactaaga aaaatgttag atgaatttga
     8581 aaaacaaaat cctgatatca aagtagaaat ggagacaacg ccttgggatc aatattgggt
     8641 taaattagaa gctgcaacaa cgggaggtaa tatgccagat gtagtaacca tgcactctag
     8701 cgaatcctat aaatatatgt cacagaatgc tttgatggga cttgatgatg ttatcaaaga
     8761 aaatgatatt gacatgggaa actttactga aggaattgct gatttctata cgcttgaaga
     8821 cgaactatac gcaatcccta aagatgcttc tgtagtgggg ctatggtaca acaaagaatt
     8881 atttgataat gcaggtgtcg attatccaga tgaaacatgg acatgggaaa cactcagaca
     8941 agctgcaatt gatttaacag atgaatcaaa aggcatctat ggttttgcat cacatattgg
     9001 aacagagact ggctactggc catttattta tcaaaatggg ggagaagtat ttgccgatga
     9061 caatacaaaa tcaggtttga ataccccaga agcacaagaa gctttagctt tttatcgaga
     9121 tattgcactt gttgatcatg cttcaccaac aattacagaa ttacaagatc ctgataagtt
     9181 aagtcgtttt caatcaggta gattagcaat gatgattgaa ggaaactggt ttgcaccggg
     9241 atttttgaaa aatgactatc tagttgaaaa tgttgcttct gccgtgttac ctaagggaaa
     9301 agttaatgca acaattacaa atggacttgg ttgggctgcc agtgcgagta caaaataccc
     9361 agaagaagtg aaaaaactaa tggcattttt agctagtgag gacgccaata aaatccaagc
     9421 ggaaacgggg gcatcaatcc cagcactaaa aggctttgaa gacgagtggg ctgcttcttc
     9481 agatacaatt gatttgagtg cttttggaaa aatgttggag tatggagtcc ctcgtccata
     9541 caataaagat ggattacgag ctgaacaagc agaagttcaa attattaacc gtattctgtc
     9601 tggtgaagta actgttgaag atggaaccgc tcaaattgaa aaagaagtca atgcgatatt
     9661 gagcggaaat taaattagtt aattatacaa tatacaggcg aaaggattct atttcgtctg
     9721 tatattaatg gatgaatacc aaaaaggggg atattatgaa aaatcgaatt tttggaaaat
     9781 atcgtaaaga tcaagtgata tggggctata tttttatttt tccaacggca ttaggattaa
     9841 ttttattaaa tatatggcca gcaattcaaa cagcaatttt aagttttcaa aaaacggtag
     9901 ggttcggtga tactgaatgg gtcggattaa gaaattacca aaaaatgttt gcagacggtg
     9961 aagtttttca gtctttatta aacacattaa tttatgcagt ggtttcgata cctagtattg
    10021 ttgtattatc cttgttggtg gcagttttaa tgaatagaaa agttaaagga ttgtcgattt
    10081 atcggacaat ttattttcta ccagtcgttg ctgcaccatc cgcagtcgca atgatttggc
    10141 gctggatgtt caataatgat tatggactga ttaataacat gttggctaaa ataggtctcg
    10201 atggaccagc atggttaacg gatccatcga ttgcgattta ttctattatc attgtaggag
    10261 tttggagtgc tattggttat aacatggtgt tattactagc cggcttataa gaaattccta
    10321 aagattatta tgaagcagcg gaaattgatg gtgctagtcc aatccagcag tttttcaaca
    10381 ttacgttacc attagttaca ccaacattat tttttgtagt tgtaacaaca gttatcaatg
    10441 ctttccaagt atttgatgtt atttttatga tgattactcc taatagtacc gccatgttta
    10501 aatcacaatc attagcctat ttattctata aacattcatt tattttaaat gacaagggat
    10561 atggttcggc aatcgttatg ttccttttag tgattatatt aattattact gcaattcaaa
    10621 tgaagttgca gaaaaagtgg gtaaactatt aaggaggcta tcaaattatg aaaaataaat
    10681 ttttttcaaa tgcgccaatc catatcatgc ttattttagg tggtattgca atggcattac
    10741 cttttatttg gatgatttta acttcaggga aaacgttggt tgaatctacc caaattccac
    10801 ctacaatttt ccctgagaaa tttcagctaa gtaactatca acaagtactt gatttattac
    10861 cattcatggc tttttatatc aatacatttt taatggttgt tggacgagtg attggctcgg
    10921 ttttattttc agcaatggct gcatatgctt gtgcgcgtct aagttttcca gggaaaaata
    10981 tccttttcag cttagtactt attcaaatga tgattcccgg ttccattttt attactccac
    11041 agtatttatt agcacaaaaa ttgggtattt taaatacaat tccagcatta atattaccag
    11101 gggtagttag tgcgtttggt acgtttttat taagacaatt tttcttaggt ttacctgatg
    11161 aattggagga agcggcctat ttagaaggtg ccaatatttg gacgatcttt ttcaaaatta
    11221 tgttgccgct tgctaaatca ggattggttg cacttggaat attcacagcg ttgtttgcat
    11281 ttaaagattt aatgtggcca ttgattgtca atacttcaat tgataagatg cctttagctc
    11341 cgggattagc aaacttacaa ggacaatatg ccacgaactt cccacaatta atggcaggtt
    11401 cgttattagc aatttggcca atagttgtga tattcatcgt tttccaaaga aaattcattg
    11461 aaggaattgc tacaacaggt agtaaattat aaaactatta attagtgatt ggagagtaag
    11521 tacatgacaa aaattacatt tattggtgca ggaagtacta tttttgcaaa aaacgtatta
    11581 ggcgatgcga tgttaactcc aagtctacaa gatgcacata ttgcattgta cgatattgat
    11641 gaaaaacgac taaaagaatc aaatttaatg cttaaaaata ttaataaaaa ttcgaatgaa
    11701 aatcgtgctg atattgtttc ttattatgat cgcaaagaag cgttaagaga ggctgatttt
    11761 gttatcaatg ctattcaagt gggtggttat aaaccttcaa cagtgattga ttttgatatt
    11821 cctaaaaaat atgggttgcg acaaactatt ggtgacacca tggggattgg tgggattttt
    11881 agaaccctac ggacactacc agtaatgtta gactttgcta aagaaatgga agaagtttgt
    11941 ccaaatgctt ggttattgaa ctatacaaat ccgatggcga tgttaaccat gggtgtttta
    12001 aaagcgacga gtattaagac tgttggttta tgtcatagcg ttcaagtatg cgtaccagaa
    12061 ttgtttgagc atttaggaat agccgatcaa tatgacttaa atgactttca atggaaaatt
    12121 gcaggcatta atcatatggc attcttgttg gaaattacaa aaaatgggga agatttctat
    12181 ccaacaattc gtcagttagc tgcagaaaaa ccaaatccac atccagattc tgtacgtttt
    12241 gaattgttga aacgttttgg ttactatatt acagaatcaa gtgaacacaa tgcagaatac
    12301 catccatact ttattaaatc aaaataccca gaattgattg acgaattagg gattccgttg
    12361 gatgaatact tacgtcgttg tgaacaacaa attaatgatt gggaaagcat gcgagaggac
    12421 attgtaaata atggggagtt aacacatacg agaagccgtg aatatgcttc atatatcatg
    12481 gattctatta cgacaggaac tccgtcagtg attgcaggaa atgtcttaaa taaaggctta
    12541 atcacaaact taccgacaga tgtttgtgtg gaagtacctt gtttagtcga taaaaatggc
    12601 gtgcaaccaa cctatgtcgg tgaattgcca acacaattag ctgctttaaa tcggacgaat
    12661 atcaatgttc aagaactgac agtagaagcc gctttaacac tagataaatc aaaaatttat
    12721 caagcagcgt atttagatcc acatctatca tctgaattgt ctttaacaga tatcaaaaat
    12781 ttagtggatg atttaatcga agcacatggg gactatttac ctgaatataa ttaaaaagaa
    12841 gctgaaagag taaggaattt tcaattcctt actcttttct tagttaaatt tagtaaaaat
    12901 attgacaaaa cacttagtaa acagttacat tagtgttaac aaaaagaaaa cgcattcaaa
    12961 ttgtataagg aggagcataa aatgaagtgg tctaaaaaaa ttattttagc ttgtatagca
    13021 ctaggagcaa cgatctcttt gactgcttgt ggaaaaaatc aggaagatgc aagcggtaag
    13081 gtagaaatag agttttttaa tcaaaaaaaa gaaatgactc aaacgattca ggagattgct
    13141 aaagattttg aagcaaaaaa ccctgatatt catgtaaaag ttgtggatgt accgaatgct
    13201 ggtgaagtaa ttaaaacacg tatgcttgca ggcgatgtac cagatgtcat taatctttat
    13261 cctcaaagta tagaattgaa agaatgggcg aaagctggtt atttagagga cttaaccgaa
    13321 gaaccgtatt tagagaatat caaaaatgga tatgcacaac gttttgctat tgaggatcgt
    13381 gtatatagca taccattaac cgctaatgtc tatggttttt actataacaa aactgctttt
    13441 gaggaaatgg ggattcaagc accagaaact tgggcagaat ttgaaaaaat agtagctgag
    13501 attaaagatc aaaacaaagt accgtttgcg attgcaggag cagaaggctg gactttaaat
    13561 ggttatcacc aactagctat agcgactgct gctggtggtg aagaggaagc gaacaatgtt
    13621 tggcgtttct cagaagttaa tggaattaat gctgaaagca aagaaatgca aaaagatttt
    13681 aatcgattag atttgttaag agaaccaaaa gctttgcaaa acaactggca aggtgccggt
    13741 tataacgata cagtagttac ttttacaaaa ggtgatgcgt tgattatgcc gaatggttca
    13801 tgggcaatgc cgatgattca ttcacaaaat ccagattttg aagtaggaac ttttcctttt
    13861 ccagcagatg aagcaggtca aagtctaacg attggcgcag gagacctagc cttatcagtt
    13921 tctgcaactt ctcaacataa agaagaagcc aaacgttttg tagaatatat gacaacacct
    13981 gaagcgatgc agaaatatta tgatgtagat ggtgcaccgt gtgctgttga gggcgttatc
    14041 gagaatactc aggattcacc attaagtggt ttaactgaac ttgcttttac tgatcgtcat
    14101 ttagtttggt tagccaaaga ttggaatagt gaaaatgatt tttatacctt aacaacaaat
    14161 tatttacaca atggcaatca aaaagccatg attaacgcat taaatgcttt ctttaatcca
    14221 atgaaagctg acggaaggta ggaaaataaa atgaaaataa aagaaatttt aaatcgttac
    14281 tgggcaatca tttttgtagc aattccaatt attttgcaga tgattttttt ctactttcca
    14341 atggttcaag gtgcttttta cagtttaact aattggactg gtctgactta taattttgat
    14401 tttgtgggtt tgaacaatta taagattctt ttttctgatc cgaagtttat caaatcgatt
    14461 ggcttcactt taattgtgac gctttgcatg attgctggac aaattggttt tggtattttg
    14521 attgcgcggg cgttgaacgc aaatattaaa gggaaaacat tctttagagc atggttcttt
    14581 tttccagcgg tcttatcggg cgtggttgtt tctttagtat ttaaacaaat ttttaactat
    14641 ggtttaccaa aaattggtag tatgttaggc attgaatttt tacaaaccag tcttttagga
    14701 acaacatggg gagcgatttt tgcagtaatt tttgttttac tttggcaagg aattgccatg
    14761 ccagtcatca ttttcttagc gggttttcaa agtattccac aagaaattat tgaagctgct
    14821 agaatggatg gggcgaatga taagcaaatt ttttggaata ttgaaatcac ctacttatta
    14881 ccaagtattt caatggtatt tattatggca ttaaaaggtg gcttaacagc atttgatcaa
    14941 atttttgctt taactggtgg tggaccaagc gatgccacaa catctttggg gttacttgtt
    15001 tataattatg cttttaaaaa caatcagttt ggttatgcga atgctattgc tttagtctta
    15061 tttatcttaa ttgggattgt ttcactggca caattaaaat tatcgaaaaa atttgaaatc
    15121 taggaggttt cccaatgaaa acatcaaaag aaaaaaatat ttctaaatac ttgcttttat
    15181 tattaggggg cttcatgatt ttagttccct tagtttcaac gctattcggt tcatttaaaa
    15241 caacacccga tattatgaat aatttctttc gttttcctaa tccagcgact ttggaaaatt
    15301 tccgaagatt gttagcggat ggaattggtc attacttttg gaattcggca atcatcacaa
    15361 tcattgcagt agttgctgtg acagcaatta ttcctatggc tgcttattca ctagcaagaa
    15421 aaatgactcg tgggaaagca tacggattga tgtatttatt tttaatttta ggaatttttg
    15481 ttcctttcca agtaattatg attccgatta ccgttatgat gagtaaaatt ggtttagcaa
    15541 atatgtgggg attaatctta ctctatctca cttatgccgt accacagaca ctatttttat
    15601 atgttggttt tattaaacta aatgtgccta tcagtctgga tgaggctgct gaaattgatg
    15661 gggctagtca ctttacaact tatttcaaaa ttgttttccc aatgttaaaa ccaatgcatg
    15721 cgacgactat tattcttaat gctctatggt tttggaatga tttcatgcta ccattattaa
    15781 ttttaaatcg tgattctaat atgtggacac taccattgtt tcaatataat tatacgggac
    15841 aatattttaa cgactatggt ccaagttttg cttcctatac agtaggaatt gtcacgatta
    15901 cactagttta tcttgctttc caaagaagta ttatagctgg aatgagcaat ggagcagtga
    15961 aataaccaat aaattattct cattataaag gagttcataa acttatgatt atatttgaca
    16021 atcacacaca aacatttcat ttacaaaata aaaaaattag ctatctatta ggaatcgaag
    16081 aaaataatta tttaacgcat ctttattttg gaaaaaagat tacgcactat tctggtgggt
    16141 atcgctaccc ccgaacagat cgttccttct cacccaacaa tgcaaatgcg caagatcgtt
    16201 tattatcttt agacacatta ccattagaat ttccaggata tggacatggt gattttagag
    16261 aaccggcgca taatattaaa ttaggaaacg gtagtcgtgt aaatgatttt cgttatgata
    16321 gctacgaaat tcaaaaagga aagcccagct tagcgggatt gccagcctta tatacggaag
    16381 atgatgatga agctgaaacg ctgattattc aattgaaaga cgcgattagt ggattgactt
    16441 tacagttgtt ctacacaatt tatcaaaatc acagtgtaat tattcgttct acgcaattag
    16501 taaataatag tgatgaaaca gtggagatta accgcttagc tagtcaatca attgattttc
    16561 caaatcgtcc actcgagtta attcatttaa atggtacctg ggcaagagaa cgtcaaatga
    16621 ctagagaaaa aattcataca gggataaaag tattagatag taaacgcgga tcaagcagcc
    16681 atcaacaaaa tccgtttgtt gctttagtag atgccaaaac agatgaattt caaggagagg
    16741 catatggatt taatttagtt tatagcggta atcacgaaac ggtgattcaa aaagatccat
    16801 ttgaccaaac acgggtcatt atgggaatta attcatttaa ttttggttgg caactaaaaa
    16861 ctggcgactc atttcaaacg ccagaagtcg tgatggttta tagtaatgaa ggtctgaata
    16921 cgttatcaca gacgtatcat gaattgtata atcaccgttt aattcgtgga aactatcgtt
    16981 taaaagaacg tcccacgtta atcaacaact gggaagcaac gtattttgat tttaacgaag
    17041 aaaaaatcat gaatattgtc gatgatgcga agaacttggg cattgaaatg tttgttttag
    17101 atgatggttg gtttggcggt cgtgaaaatg acttcacttc attaggtgat tgggttgaaa
    17161 cagaaggcaa acttgcttgt ggtttggaaa atttagccaa gcaagtgcat gataacggga
    17221 tgaaatttgg gatttggttt gaaccggaaa tgatttctga agatagtgaa ctatttcgag
    17281 cacatccaga ttgggcattg ggtattccag gtcgtgaccg ctcaattagt cgaaatcaat
    17341 atgttcttga tttttcaaga caagatgttc gtgataatat ctatcaacaa atgacggcga
    17401 tttttgatcg tgtaccgatt gattatgtga agtgggatat gaatcgaaat atgacagaag
    17461 tctattctgt cttgttggac tcaacgatgc aaggtgaagt ggctcatcgt tatatgttag
    17521 ggttatatga atttttagaa aagttaacaa cgaattatcc aactatttta tttgaaagtt
    17581 gttcgggtgg aggcggtcgt tttgatgcag gtttcttgta ttacatgcca caaacttgga
    17641 cgagcgacaa taccgatgcc gtggctcgtc tgaaaattca atatggaacc agcttagtgt
    17701 atccaatttc aagtatgggt gcgcatgttt cagcagtccc aaatcatcaa acaggaagag
    17761 aaacgagttt aactattcgt ggcaatgctg cgatggctgg tgtttttggt tatgagctag
    17821 atctaacgca attaacttct gaagaaaaag cagaaattaa agaacaagtt gccttttata
    17881 aaaagcatcg ccaacttttg caatatggaa ctttttatcg cttggaaagt ccgtttgaag
    17941 gcaatgatac tgcatggatg tttgtctcaa aagaccaaac agaagccatg gtcttttatt
    18001 tccgagtatt agcagaagct gcgcatccat tagtcacatt gaaattagca ggattagcag
    18061 aagaagcaac ttatcaaatg gaagatgtaa catttgctgg cgatgaattg atgaatctcg
    18121 gtttttatat tgactcagaa ctacatggtg attatgcgac acaacgcttt tatttgaaac
    18181 agatatagta gcttgaattt acaatataag tgcaacacca aaagagactc attccaaacg
    18241 aagaaaatat gttttattta cacgcattta ctaaaaagca gcctgatttg aattgggaaa
    18301 atgaagaagt acgtgaagaa atctatgcaa tgattaacta ttggttagat aaaggactag
    18361 gcggatttag aatcgatgcg atattaaaca tcaaaaaaaa actagagtat ggcatctttg
    18421 aatctgatgg agaagatggg ttagccttca ttgggccctg gattcttaat cagtcgggca
    18481 ttgaagtgtg gttaaaagaa atgagagagc ggacatttaa accacataat agtatgacgg
    18541 tagcagaagc cgatgttcct aatgaacgtt tagatgaata tattggtgaa gatggctatt
    18601 attcgatggt ttttgatttt agttatacgg atattgatgt acctgaaact ggtgaatggt
    18661 ttaaagatag ccaatggaca tggacggata tgcgtaccaa tatttttacg aatcaattag
    18721 ttacgcaaga taaaggttgg ggcgccttat atttagaaaa ccacgatcaa ccacgttcaa
    18781 ttaataaata tattccagaa gaatggatca atgattatag taaaaaaatg ttggcgacgc
    18841 tttttatgtt actaagaggt acccctttta tttatcaagg acaagaacta ggaatgacca
    18901 acatagaaat ggcatcatta gaagattttg atgatgtagc tacgcattct cagtataaac
    18961 gggcattaga atatggattg gcaccagagc aagcattgaa agctgtcaat aaacgaagtc
    19021 gggataattc tcgcacacct atgcaatgga atacgcaaaa aaatgccaga ttctcaactt
    19081 ctgataatgt atggttaaaa gtaaatccta attatccaga actcaatgca gaagctcagt
    19141 taaccaatca acagtcggta ttcaattatt atcatcaatt aattaaatta agaaaaaata
    19201 gtgtatacaa agacgtgcta atctacggac aatttctacc agtgaaagat aaaaatgaac
    19261 atattttgct ttatgaacgc caattagaag ataaaatcgt attagttatc ttaaacgtta
    19321 cagcaacaga acaagaatat tatgtagatg aacagtacca acaagtatta atcaataatt
    19381 atgaagatgt tttattagat caaagtcgaa aattgcgttt acgaccgttt gaaagtattg
    19441 tattagctaa ttatggagga caattatgaa aattaaaaac gaagcaatgc tcatcaccta
    19501 tgcagatagt ttaggaaaaa acatgggcga attaaaacaa gtcttagaca aacatttaca
    19561 aggtgttatt ggtggtgtac atctgttgcc tttttttcca tcgacaggtg atcgaggctt
    19621 tgcgccgagt gattatacga cagttgatcc agctcttgga acatgggaag atgtggaagc
    19681 attaggtgaa gattattatt tgatgtttga ttttatgatt aatcacattt ctcgtgaatc
    19741 aaaatttttc caagatttca aaaaaaacca tgagcagtca ccatacaaag aaatgtttat
    19801 ccgtattcat gaatttttcc cagaaaatcg accaacacaa gaagatattg atttaatcta
    19861 caagcgtaaa gacaaagcgc cgtttcaaac ggtagaattt gcggatggta cgacagaaga
    19921 ggtttggaat acctttgggg aagaacaaat tgatttagat gtgaccaaag aagttgtgaa
    19981 agaatttatt cgagaaacca tcaaagatat ggcgaaccat ggctgttctt taattcgatt
    20041 agatgcgttt gcttatgcga ttaaaaaatt agataccaat gatttcttcg tggaaccaga
    20101 tatttgggaa cttttagacg aagtgcgtca agaagcagcg aaatatgacg tcgaattatt
    20161 accagaaatc catgagcatt attccattca aatgaaaatt gccaatcatg attattatat
    20221 ctatgacttc gccttgccaa tggtcactct gtattcactt tatagtggaa aatcagaacg
    20281 tttagccaat tggttgaaaa tgagtccgat gaagcagttt acaacattgg atacgcatga
    20341 tggaattggt gttgtggacg ctcgtgattt attaacagat gaagaattgg attacacctc
    20401 tgaggaattg tataaagtcg gggcgaatgt gaagaaggtc tattcaagtg ccaattacaa
    20461 taatttagat atttatcaaa ttaacagcac ctattatagt gcattaggcg ataatgaccg
    20521 tagctatctg ttagcacgtg cgattcaagt atttgcgcca gggattccac aaatttatta
    20581 cgttgggtta ttagcaggaa aaaatgatat tgaactgttg gaagcaacga aagaagggcg
    20641 taatattaat cgtcattact atgatttagc cgaaattgaa gaagaagtgc aacggccagt
    20701 gattcaacaa ttatttgcac ttttaaaatt tagaaatgaa tctgcggcgt ttgatttgga
    20761 tggaacgatt gaagtagcaa cgccatcaga atcagaaata gtgattacac gtaaaaataa
    20821 aaacggtagt gatagtgcaa cattaacggc taacttggat acgaaagaat ttatcattga
    20881 gtctaaagat ataaaaattt tcactagtgt tgcattaaaa ttttaaccta ttccatagaa
    20941 caaaaaatcc tttatactag cacttggatg acttatccaa gaccaataaa aaggactcat
    21001 acatggataa gtataaaaca aatacagcat ttaataaatg gttttctgcc ataaaattag
    21061 gaaaactttc tgtcaactcc caaaaatgta tttttgatta caattcgtat cgtaaaaaac
    21121 tgtcttttga agctgtgctc aagctctttc tctacgcagt taatgaagaa aaagaaagtt
    21181 tgcgtgattt gagtacagct cttatcgacc gaccgctcca actagaaacc gatgtgtcat
    21241 cgattagtca tacccaattg tctcgagcat ttaatgcact tgaacctaaa gtgttagaag
    21301 aaatttttca acaactgtta gaaaaagttc aacatcaaat caaaccaacc aagcgaaatc
    21361 atctgtatct gattgattcc agtacgtttt cgcttagttt aaaacgtcat aagtgggcga
    21421 ctttccgtca aacaaaatca ggtgtcaagt tacacttaaa ctattgttat atggacgata
    21481 ctacgatgta tccaactgat tttaccttaa caaatgccca tgaacatgat ctcaatcaac
    21541 taccagtatt ggtgaatcaa ccagaggcaa cttacgtgtt tgatcgtggg tattaggact
    21601 ttgaaaagat ggatcagatg cattgggatg gctatttctt cgtcactcgg attaaaaaaa
    21661 acaccaaagt tcacgtgata gatactctgg aaacatcgcc agaaacagaa attctacgag
    21721 acgagctggt tcgtttagga tctaaaacct atctaaccgc caatttccga ctagtcactg
    21781 ttcaagataa gaacggacgt gtgtttcaat ttatcaccaa tcgaatggac gtctcttcaa
    21841 aagaaatctc tgatatgtat cacgctcgtt ggcaaatcga attgtttttc aagcacatca
    21901 aacaacacat gaccattaaa accttctttt ctcaaagtga aaaaggcgtg cagaatcaat
    21961 tgattttaac gatgatttcc gctctcctca cgtttctcat caaattggag acgaaaacgg
    22021 aaaaatcagt gttccaaatc aaacgattct ttcgttattt actgtttcag ccctttgaat
    22081 gttgtctaga aaaattaatt cccacatgag aaaaaagaaa tttggctcgt tacttttggt
    22141 tttcagttga ataacagata aaaaattttc tggaaaaagt catcctctgc gtcagcacag
    22201 ttttttttga cttattttca gaggaaatag ttttcagaat attctaaaat gttttatgca
    22261 acactagtga tattttttag aattagattt ctaatgtgca ttttttgagt attaaggagc
    22321 aagtatacaa agatttataa agctgattaa atttgaataa aaatatgcag gaacgctact
    22381 atttttagta gtgttctttt ttatatttga ataaaaaatg tggtggttaa atggtggtta
    22441 taacaaaaaa tgaattaatg aaattaggtt atgggaagta tcagtctgag agaatcatac
    22501 gacaggcaaa agcaattatg gtttcaaaaa gctataccta ttacgaaaat agaagattag
    22561 gactagtacc tgttgaatct gtagaagaag ttttaggtat gaagatagag gtagaggagg
    22621 attttcagaa tcatggttaa ttttaaaaaa gataaaaatg ggaaatatca ttttactgct
    22681 agtttgggat tcgacaaacg aacagggaaa agagtacaaa aaaacgtaga ggggttaaaa
    22741 cagttaaaga agaaaaaaag cgtataccga acttgtttct aattatggaa aagaagcaga
    22801 aacttctcaa agtactatgt tgtttgagga gtttttttat aaattattcc taccttatta
    22861 tcaagggaaa gtagaagaaa gaacatataa aaatcggtta tctacaatca aaaaaacttt
    22921 tcttatttct ttaaaatgga gttaagagaa atacgtccaa ttgacattca aaagtggcaa
    22981 aataatttat tgagcaaata taaaaattct tatgtaagaa acatgtatgg gatttttcag
    23041 atgtcattag atcgagcagt tgttttggga ctacttgaaa aaaatcctgc aaaagttatt
    23101 ggaaatgtga agaaaaggaa aactacagtt gatttttgga caaaagaaga atttacaaaa
    23161 gttatttcaa ctttttatat tgatgatttg taccaacatt ttggttttat ttgtatgtgg
    23221 ttacttttta tgaccgttat gcgtttggga gaagccactg cattaacttg gaaagatatt
    23281 gattttgaaa ataaaaactt gcgtgtgaat aaaacactct attataagag agccaaaacc
    23341 tatgagtttg tagaacccga aacggcttct agtattcgta caatcgaact agacgacaat
    23401 acaattacct ttttaaaagc ttggaaggag cgtcaagttt caataggagg catgtcgttt
    23461 gtactttctt ataatggaac acctactcag aaatatacaa tccgtcatat tatgagaaga
    23521 catgcaacga tcgttggtgt tcatataatc cgcatacacg gattaaggca tagtcatgct
    23581 tctttgctta tatcacaata aaaagatgca cttcgaatta aagaaaggtt aaaacatgct
    23641 gatgtacaaa cgactttagg aacttatggt catttgtatc taaattcatt gagagagata
    23701 acaaatgatc ccacagatta tatccaaact aatttttcta aaatcaaacc gacacctatt
    23761 tacgataata aaaaataaat gataaacaaa agtaggatca caccaaaaga aacacactag
    23821 aaaaactata atacaggctt ttctagcgtg ttgtttctta tttccgccta tttatacatt
    23881 atactcataa agcatttaat gcatcgatcg tagccgcatt gtctatatgg gtatataaag
    23941 ttgttgtatt ggtacttgaa tgtcccaatt gttgggcagt taataccaat gaatttgtct
    24001 gttggtagag tctagtagct aatgtatgac gcagtttgtg agggctgact tgaattctaa
    24061 agccttttga atattttgct accatccgtt cgattgcaat accggatata cgcttggctt
    24121 ctccttggta aattgctaga aataaagctt tttcgttttc tgttacttta tatcgttctt
    24181 tccgaatagc tagataatta gctaaatatt ccattgcgaa tgctgctata ttgacagcat
    24241 ctcttttatt tccttttcta gttactacca cattattctt atctaaagat aggtcatcta
    24301 aattaatatt tataacctcg gagagtctca atccagatcc taaaatcagt gcattgatcg
    24361 ccaggtctct ttctacatct cgttgataat agatcaaagc tcgtttactc aaagtatttt
    24421 tatattcatt ggcaatataa tctagataat tttgtgtatc cttatctaga aataattttt
    24481 tctcaatggc attggcacgt gcagctaacg tagttttatc tgtgatggtt gctacttgat
    24541 ccataggatt attgtctaag tatggttttc ctagaggatt attggaactt ttcgaaagat
    24601 atttaaatag aacctttaat gccgtgatat ttctattgat agtagaagta gatagaccta
    24661 agttattatt atctttgagc ttagtttttg ttgtctcttt ttttacattt tcttttgtgc
    24721 gacgtttcaa atgagatttg tacaagttta ggtcataggc agttaactgt cttatcgagg
    24781 tgatagaagt atcaggaacg atagactcac tcagaagcca ttcataaaag agcttataat
    24841 tttttagata ttctaaagtg gttcgaggtg attgatcttt atcctcacga tcttgaacaa
    24901 aatcttttat ataatcgggc atatgaagta tgattgtatc tattttttga tatatttctg
    24961 tatttttcat gtcattcatc ctttcaataa gtaggggaga agagtatctc tataattgga
    25021 ctataccaat tatagaatgt tttgtcaatt ggtatgctct aaaatttatt aatttgtttc
    25081 aaaaaaagca tataaacagg tatacgttta ataatttaaa ataaatggta tacataaata
    25141 gggaaggaaa tagaagggag caatctaaat tttttgaatt ttcttaatta attatataga
    25201 aagaacaatc tttctataga gttagacatg agagggacta tgcttgattt aaaatcaaca
    25261 agcgtatata ctgtatatac aaagaaaaag gagggagaag actatggcaa ttaaagaaag
    25321 aaaatttagg gaagtgggga actcagtagt attaactatt tcaaaggagt ttcttaaaga
    25381 aaatgggtta aatcccggag atacggtttt tttagatgaa gaaaaacttc gagcggcaat
    25441 tacaaaaaaa caagccttat ctgatgaaat tgatttagca atatctcaag cattaactga
    25501 atatgatact acttttagag agcttgtcga taaatgagta ttcattacct agaagccaaa
    25561 gatattataa aaatgaatgt aatccaaata aaaaaatact ctcctaatga accccttggt
    25621 gtaaaggatg cgaatgcttt agaaatgtgt gtagggcaac ttcgagcctc agcttttggt
    25681 gaagaggttt atccttcgat ttatgaaaaa gcagctatcc tacttataca attgataaag
    25741 aaacatcctt ttcacaatgc aaataaacgt actgctttct tagctacttt tgtctttttg
    25801 aaaatcaatg gacagctttt agctattgat caaaaagatg ctgtaaattt agcggtatat
    25861 attgctacgt atgataagga tttcgatcaa ctaaaatatg aagtgatcaa cactataaag
    25921 acacatacgc agcccattta aggagttact gtatgtgtct ttatagggtt attagctgct
    25981 atagcgaaat aattgaagta aattacaaat agctataatt caaatccaac tatatagaaa
    26041 acgtaaattt tctatatagt tggattaaga taacgactat ttattttatc atatttttac
    26101 tataccctat acttttactt ggtatattta tgaataatcg caaatttacc cctatactac
    26161 tagtttgtaa gttagattaa taaaaatact aaagttattt gttcttttat taaatacacc
    26221 tacaacttat aaattgatgg tatttagata acacgaaaga ataaaaataa cagctgatag
    26281 taaagtttgt tgacgattgc tactcaatcg aaagtgagtt agtgcgtatg aacttgcttc
    26341 tgaaaactta tgaaatgaaa gaccttttac atcttgcaga aatcggtact gggattaaac
    26401 taagcaataa aaactaatgt tcccctcatt ctttgaactt ctactatttg atttatttat
    26461 tctgataaat gacgatttca ccttcaggat cttcaaatcc cgtatagaat ttatttaaga
    26521 tctcttcagt atcagtaata ggataggcga taggccacat accctttgat ggttagaata
    26581 aactgctcaa aatctgtatc gtatgttggc tttagcatat taacaaaggc tatctccaaa
    26641 ttataaacca taagcgttga atcgttctta acaatttcaa ttcttcctaa cccaaagtca
    26701 gaagatataa ttaccggact tgccttaccc ttcatgtggg ttgttgagat tccatattta
    26761 aagggaattg tcggtactat cggcggtctg aaaaacatcc caaaaataaa aaaatctttc
    26821 ccctgctagt ctcctaagtc cctttgtagc ggatatggca ccataatctc attttatcga
    26881 agtgagtcat ggtttatctg ttggccaacc aaaattgata caatctaacg atgcaccctc
    26941 tacggcattc taggggagtg cacttgcatt cacccaataa aaaccggcag ttagcaaaga
    27001 acttatgtag tcgtatgttc ttactgttaa catacaagag gtctcctttc cacaattgct
    27061 tagcagtaaa cgggaattta caaagctaat ctcttccatt ttcttatctt tgttctaaaa
    27121 gtcccaaatg gagcaactgt atttacatga ataaatttat atacttccca tacagccgtt
    27181 ttggttgcct cgtctgccca ttttcttttg tgtgcagtga atagatcttc atcactcatt
    27241 gaatcaatca tcatgttaat atcatcaata ttacgattga gaatttcctc taattctttc
    27301 aatggtagat gtgcataggt atttgtaaac cacttatata actctcctaa ctgattccat
    27361 ttaaattgat cagaaggcgt tttaacagat aatccatttc tttcatcatt ttcccatttt
    27421 agaattaaat tcgtccaacc aacttgatat gctaaatttt cagcaggtgt tctatccact
    27481 tcctcaactc ttttatcctt caattcttca ggaatagttt caaattctaa aatatattta
    27541 gtataagtcc tatttatttc tttttttaat tcttctttat ttttatatgt tctcattata
    27601 ttacctccat aaattcctaa ttgtctcctt taattcatct ataatttcat ccacgatatt
    27661 ttaatccgtt ctacaatgca tatctgatat gcattgactg tctaactcat atgtgaatga
    27721 tttataaaat atcccaacgt ctcatctaaa gaaatgttga tcgtcagcaa ggagctaaaa
    27781 aatacgaata tatttctttt gtagtaaaat cggactggtt tgcatatcat tttcttcgta
    27841 aatatcaaaa tcatgttaac tactatcaat tactaataaa aactaccact ttaagcgtta
    27901 agaactgtta agtttagtta agtgaggata gttcacaaaa tccattgtta aacttcacga
    27961 aagtggtaaa actcaaaatg ctttatatag gattacagca tcgctctttc ttcgattgcg
    28021 cgttgggtaa aaaatattat gaagtaaaaa ttgacgatga cacgttcctt acggctcatc
    28081 agatgaaaca gctacaaaaa cgaaatgatc aactcgaaga aaatttaatt ctaaaaaagc
    28141 gattgccata ttcacgcctc gctcgacgaa ctattaaagg tcaagattta cctgaagatc
    28201 atccttttta ggaaattgaa gctttttatg ttgcacaatg catttataat actacaatga
    28261 tgttttcacc agatattctt ctagggtgcg gtgtaatgaa acagatacac ttgcaaaaga
    28321 aaattcaccg cgaatttact aaaattatga ataattatgt taatcttccg aaattttttt
    28381 ccaaaattaa gggatcaagc tggtgttata gattgtttaa ggttggcaaa aaaataactt
    28441 ctttttaaac aattatagaa aaccgatact ctgttaagtt ggttgacacg gtgtcgattt
    28501 ttatgacttt cttattctga aacttcacta acggacagta cctaaaaagt ctatagtatg
    28561 gacgtttacg agtactattt tatcaaaaat gctgctcatt tcaacttata tgttttagtg
    28621 aactaccccc acttagcttg gataggctac aattaactag acagaaaaat taaggtgtgt
    28681 agactagaag aaaacatacc aggaggaatt tttatgtcta agagaacacg aagaactttt
    28741 tcacaagaat tcaagcaaca aatcgtcaat ctttacttag ctggaaagcc acgtgtagaa
    28801 atcattcgag aatatgaact aacggcttca gcatttgaca aatgggtaaa gcaat
//
LOCUS       DAZULR010000034        28707 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.034, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000034 DAZULR010000000
VERSION     DAZULR010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28707)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28707)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28707
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.034"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(18..293)
                     /locus_tag="ACG8ZV_001770"
     CDS             complement(18..293)
                     /locus_tag="ACG8ZV_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997104.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            587..1402
                     /gene="thiD"
                     /locus_tag="ACG8ZV_001771"
     CDS             587..1402
                     /gene="thiD"
                     /locus_tag="ACG8ZV_001771"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HFS4997105.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKDAQQETVNDYVLLESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(1607..3058)
                     /gene="cls"
                     /locus_tag="ACG8ZV_001772"
     CDS             complement(1607..3058)
                     /gene="cls"
                     /locus_tag="ACG8ZV_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HFS4997106.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQKALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            3400..6066
                     /locus_tag="ACG8ZV_001773"
     CDS             3400..6066
                     /locus_tag="ACG8ZV_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFS4997107.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNE
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            6430..7182
                     /locus_tag="ACG8ZV_001774"
     CDS             6430..7182
                     /locus_tag="ACG8ZV_001774"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFS4997108.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(7204..8358)
                     /locus_tag="ACG8ZV_001775"
     CDS             complement(7204..8358)
                     /locus_tag="ACG8ZV_001775"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HFS4997109.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            8543..10984
                     /locus_tag="ACG8ZV_001776"
     CDS             8543..10984
                     /locus_tag="ACG8ZV_001776"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HFS4997110.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKPYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     KVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(11314..12018)
                     /locus_tag="ACG8ZV_001777"
     CDS             complement(11314..12018)
                     /locus_tag="ACG8ZV_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997111.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(12205..12450)
                     /locus_tag="ACG8ZV_001778"
     CDS             complement(12205..12450)
                     /locus_tag="ACG8ZV_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997112.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(12467..13318)
                     /locus_tag="ACG8ZV_001779"
     CDS             complement(12467..13318)
                     /locus_tag="ACG8ZV_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFS4997113.1"
                     /translation="MNSLTSTYRLLNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQPTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            13484..14488
                     /locus_tag="ACG8ZV_001780"
     CDS             13484..14488
                     /locus_tag="ACG8ZV_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HFS4997114.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            complement(14716..15675)
                     /locus_tag="ACG8ZV_001781"
     CDS             complement(14716..15675)
                     /locus_tag="ACG8ZV_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFS4997115.1"
                     /translation="MTYTHLTTDELVMIESYFKINQSVAKTAHFLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIR
                     CSARTIYRMFKKGLFNPSDLPMKGKRKPNGHQERRGKQAFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIENKLNHWFESVPKNLFK
                     SITFDCGKEFSNWKQISNANDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     VDESFIQSVASKRNNIPRKSLNYRTPLEVFLSYVSIDDLSNLI"
     gene            complement(15794..16150)
                     /locus_tag="ACG8ZV_001782"
     CDS             complement(15794..16150)
                     /locus_tag="ACG8ZV_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFS4997116.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            16518..17705
                     /gene="tuf"
                     /locus_tag="ACG8ZV_001783"
     CDS             16518..17705
                     /gene="tuf"
                     /locus_tag="ACG8ZV_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HFS4997117.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            complement(17893..20484)
                     /gene="mprF"
                     /locus_tag="ACG8ZV_001784"
     CDS             complement(17893..20484)
                     /gene="mprF"
                     /locus_tag="ACG8ZV_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HFS4997118.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLVSVLPMIGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDP
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(20510..21271)
                     /locus_tag="ACG8ZV_001785"
     CDS             complement(20510..21271)
                     /locus_tag="ACG8ZV_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFS4997119.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            21438..22070
                     /locus_tag="ACG8ZV_001786"
     CDS             21438..22070
                     /locus_tag="ACG8ZV_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HFS4997120.1"
                     /translation="MKRKRLSIIRILFYMIILTVIGAVLFLGGRTYRSVKRVESYQIE
                     ITTAAKNYHMENYENLIKAIILTESKGKGTDLMRSSESLHGEAEIIDNPADSIDQGVK
                     YLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHGGENTVELAEAYSKDVLSPLLG
                     NEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKMNEKIIETYEKVFK"
     gene            22129..22989
                     /locus_tag="ACG8ZV_001787"
     CDS             22129..22989
                     /locus_tag="ACG8ZV_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HFS4997121.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            23174..25489
                     /locus_tag="ACG8ZV_001788"
     CDS             23174..25489
                     /locus_tag="ACG8ZV_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFS4997122.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            25671..27512
                     /gene="dnaG"
                     /locus_tag="ACG8ZV_001789"
     CDS             25671..27512
                     /gene="dnaG"
                     /locus_tag="ACG8ZV_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HFS4997123.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            27536..28645
                     /gene="rpoD"
                     /locus_tag="ACG8ZV_001790"
     CDS             27536..28645
                     /gene="rpoD"
                     /locus_tag="ACG8ZV_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HFS4997124.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
BASE COUNT         9259 a         5083 c         5946 g         8419 t
ORIGIN      
        1 taaagaacag ttagaagtta aaattgctga ttcacataga gtttatgact tcttggaaat
       61 tctttttcaa tcagtttttt catctgttta tgaaattctt ttttttcagt aaacataaag
      121 gtttgggtat cgtaaccttc ttcatgtagg aaatagatta ttcctttttc tgtgttttgc
      181 gtataagctt ttatactcct gtcttttttg aaagaacaga tcgtatagcc atctatttgg
      241 tctggtagtc gtttgatttt cttcaaaatg acttttttat cctcaagttt catttttttc
      301 acctgacttt atttttttca tatggaaatc atagcgcctt tggttatatg aaaacaagaa
      361 ggatactgaa atatatataa atcaaatagt ggttatttat tattagaata gcgaatacaa
      421 acaaatgaca actattttct gatttattac aaatgttttt tcaaataaat ttgattacca
      481 agaaaaggta gtggtatatt tactgaggga tactttgaaa aacatatgat agaaacagta
      541 acagcattat gaaaaatctt tttataaaaa tggaggaatc gatttgatgg aagatcagta
      601 tgtacaagca atgacgatcg caggatcaga tagcgatgga agcgcaggga tgcaagcaga
      661 tatgcataca ttctttacaa gaaatgttta cggtgtttct gtcatgaccg catgtgttgc
      721 aggtaattct tacggaatcg gagcaagtgt gacattgcca acagatttta tcgacaaaga
      781 atttgaactg attgcgaagg actttcaaat acgtgcagct aaaacaggta tgctagcaga
      841 ttcaaagttg attgagacag ttgtaaaaaa ttaccaaaaa tatgattttg gaccattagt
      901 cgtggatccc gtaatcgtaa cgaaacatgg aaatctttta ctagaagaat ctgctttgca
      961 aagcttgaaa gaaaagcttg tccctttggc cgaagtactg acacctaatt tttatgaagc
     1021 agaaaagctg actggacgga cattagcagc tgaagaagat tttgtgcaag cagcaaaaga
     1081 actgcaagat atgggtgcaa aaaacgttat gatcaaagga catcatgcta aagatgcgca
     1141 gcaagaaaca gtcaatgact acgtattgct cgaatcagga aaatcatttt ggttaaatgc
     1201 accattttat cctaccgacc ggatcaacgg aactggcgat tcgctatctg catgtattgc
     1261 agctgagtta gcgaaaggaa aaacagttga acaagcgatc cgattggcaa aagactatgt
     1321 aaaccgtgca attcgtgaag aaataaatgt agggcacaaa tatggaccca tcaatcattg
     1381 ggcagctggt gaattagagt aaaagaaaga ggtcgtgagc ctgccgtcca gctccgagtc
     1441 acaaggaaca agttcaaaaa acagcttctc atgtttgttg aatattgtga cttgtgaccg
     1501 aggagttggc aggagaacac cgtttgttcg gaagaaggga ctgtgacaag atttttgtca
     1561 cagtcccttt aatcttagta tatttttctc tacttgaata aaaaaattat aggattggag
     1621 aaaataatcg agaaatttgt tgcttgaata atagccagtt agacatttcc ttgactgttt
     1681 cagttgtcat ggatgaacaa tgtgtctcat cttctttgaa ctgagtagca agttcttcta
     1741 aaaactcagg atcgtaaatg acagcacttg tttcaaaatt caatcggtag ctacgaatat
     1801 cttgatttgc tgaacctacc atgcagattt catcatccat tatcaatgtt tttgcatgga
     1861 ggaagccgtt ctcatagaca aggatttgta cattttcctt gatcagctgc cgagcataat
     1921 attgtgttgc tcgataaata aaaggatgat ccggtttgtt gggaatcatg attttcacat
     1981 ctacaccaga ggcagttgcg atttttaaag cagcaatgac actttcatca ggaacaaggt
     2041 aaggtgtctg tatccaaaca cgttttttag cagaagtaat caatttgata aatgaaagct
     2101 tgatttgttc cctttcgtta ttcggtccgc ttgaaacaag ctggatggat gtatcagcaa
     2161 gcttagattc atctcgatct gcttttttaa agaaataatt caaatgatag ccgacctttt
     2221 tttcttcagg taccgagacg ttccagtctg ttaagaagcg aagctggagc aaagaagaag
     2281 cggcaccgaa aatccgtata tgcgtatcgc gccaatagcc gaattttttt gttgtattta
     2341 catattgatt ggcaatattg aaaccaccgg tataactaat ctttccatcg atcacaacga
     2401 tttttcggtg atcatggtaa ttcaatcgga aacgaagtaa tgccttttgt gaggtaacaa
     2461 atgtatggac atgtccacca tttttgatta gacgattgaa atcttttgct tttgtaccat
     2521 gagagccaaa tgcatcatat aatattcgaa cttccacgcc ttctgcggct ttttcttcta
     2581 aaacatgtaa gacttgctgg ccgatattat ctgtcacaaa tgcgtaatat tcgatatgga
     2641 tcgaatgttt ggcttttttt agatcttgaa gcagtgaatc caatttctct tgtccgtctg
     2701 tgagaagagt gacagaattc attcttgtca gcggcatacg atttaatgaa gagaagaagt
     2761 cgacaaattg ctgtttgtct ttatcgccca tgtcaggatc gtaatgttca atggtatctc
     2821 ctctaaaaga ctgaaagttt tctaattctt tcaagtcact ttgtcggaga tagaattttt
     2881 tcttatccgt taatccacgt ccgaaaaata aatataatac aaagcccacc ccaggaaggg
     2941 caaacaatac taagagccat gcccaaatgg ctgctacatc tcggggtttg atcaaaatag
     3001 ccaccaaagc aataagtgca tttaatagat aaagggcggt tataatacta gataccacaa
     3061 aaatgttcct ccttacatac aataacatta gtatagcatg atagaagaaa gaagcctacc
     3121 aaggtgaata tacttttcac tcctttcatg aaaatgtagg taaatcgggc taaagtagtt
     3181 gctttttgta ggttaataag gtaggatatt agtacagttg aatatctcct taggggagta
     3241 accggcaacg tttgttgcga taatatcaac agtaagttaa ccaaatggtt ttctggtatt
     3301 gtatgaaatg gtgagaccta agacaaatgc gtatttgtct taggtctctt tttttttcag
     3361 acaggactag ggccaagatc aaaaaatggg ggatgaaatt tggaaaacaa ggaacaagca
     3421 caacaagcgg tctataaaga aacgatcgac tcgttgatgc agcaaacgca gagctcaacc
     3481 gatggattga gcaccacgca agcgaaggaa aaattagaaa gagatggctt gaaccagcta
     3541 aaagaaaagc cgaagaagcc aacttggaaa ttgttcttag aaactttcaa agatgcaatg
     3601 gttatcgtat tgctgattgt cgcactgatt cagatggtca tgggtgacta catcgaattc
     3661 ttagttattt ttgcagtatt gatgttgaat tctataatca gtgttgtcca aacaaaaaaa
     3721 gcagaaggtt ctttagaagc gttgaaaaac ctttcagcgc ccgatgctcg agtgattcgt
     3781 gatggtaagg aaaaaacgat tccggcaaac gaacttgtgg taggagatat cgtgttgtta
     3841 gacgcaggcg attatgtacc tgctgatgga cgtttactag atgcgggatc attaaaagta
     3901 gatgaaggta tgctgacagg agagtcgact tctgcagaaa aagaagtaac ggatatcaca
     3961 agtacggtac caatcggaga tcgtacaaat atggtattca gtggaacgat cgtaacttac
     4021 ggacgcggta aattcttagt gacttcaact gggaataata cggagatcgg acaagttgct
     4081 ggccttttgg aatcaacaac tgagcaagtc actccgttac aacgaggtct ggataaattc
     4141 agtaaaaaac taagtctggc tattttggca ttgtctttat tgattttagg tatccaactg
     4201 tttcgtattt atcttggaga aggtacagga gatatgactg cagatatcgt cagcgcagtg
     4261 atgtttgccg tagccgtagc cgtagctgct attccagaag cattacagtc tatcgtaaca
     4321 atcgtgttat ctttgggaac gaataaaatg gcaaaacgtc atgccattat tcggaagctt
     4381 ccagcagttg aaacacttgg ttcgacaagt atcatctgta cagataagac tggtacattg
     4441 acacaaaaca aaatgacagt tgttgactac tttttaggta atggcgatac tggggatttc
     4501 acaaatgacc cttcaaaatg gacagctgac gaacgtcgct tgatcgaaat cagtgtttta
     4561 gcgaatgatg catcgatcag tgaagacggt actaaattgg gcgaccctac ggaagtagcg
     4621 tttatcgact ttagtgaaaa attaaaccag ccttatcagg aaatccgaaa caactaccca
     4681 agacaagcag aacttccttt cgattctgat cgaaaattaa tgtctactgg acacacgatc
     4741 gataacgaaa attacttgtt tgtcaaaggc ggaccagata tcgtcttcca acgcagtaaa
     4801 aaagtattgc taaatggtga agtcgttccg atgacggatg aattgatgaa aaaattccaa
     4861 gagcaaaatg aagctttttc aacacgcgca ttacgtgtac tagcttttgc ttaccgtcca
     4921 cttgataatt ttgatttatc atttgaagat gaagacgatt tgatccttgt tggtttgctt
     4981 gctatgatcg atcctccacg tgctgaagtg actcaggcgg taacagaagc aagaagtgca
     5041 ggaatcaaaa caatcatgat tactggtgac cacaaaacaa cagctgttgc tatcgcaaaa
     5101 caaatcggga tttttgaaga aggaaacctg gctttgaccg ggacggaact agatgaattg
     5161 acagaagatc aactaaacga agttttagaa aaagtcactg tttatgcacg tgtttcacct
     5221 gagaataaaa ttcgtatcgt tcgtgcttgg caaaataaag gtcatatctc agctatgaca
     5281 ggtgatggtg taaatgacgc accagcattg aaacaagcag acatcggaat tgctatggga
     5341 acgggtacag atgtggcaaa agatgcagca gcgatggtat tgacggatga taactttgct
     5401 tctattgtca gcgcagtaga agtaggacgt aatgtgtttg ataatatcaa gaaagctatt
     5461 tcttatctat ttgcaggaaa tttaggtgcg atcattgcga tcatctttgc cttagttgct
     5521 gactggtcca atccatttac agcattacaa ctgttgttca tcaatttagt caatgattca
     5581 ctgccagcaa ttgcattagg tacagaaaaa gctgaacctg ctacgatgaa ccgcccgcca
     5641 agagatccaa attcaggaat ctttacggac aaaacattga tttctgtaac gtatcgtggt
     5701 gtgctgattg ggattgctgt tatctttgct caatggcttg gcatgcagca ttcacctgaa
     5761 ttcggtgtag ccatgtcatt ttcaacattg atttggtgtc ggacattgca aacattccca
     5821 gcacgttcaa acacacaaac agctatccaa gcagggttct tctctaacag aagtgtctta
     5881 ctagctgtag ttgtatgtag cgcgctttac tgcttaacaa tgatcccagg actgaaagaa
     5941 gtcttctcta tcccatcagc atttggattg acagaagtct ttacatgtat gggaatcgca
     6001 cttgtgacaa ttgttttgat ggaaatcact aaattgatca ttgtacgagt acaaggaaat
     6061 aaataaaacg aatcaacgag gttgtgagcc tgccgtttaa ttctgagtca caaggtgcaa
     6121 tttcaacaaa cagcttctca tgtttgttga atattgtgac ttgtgaccga agagttggca
     6181 ggagaacacc gtttaaggaa gaagttgtaa aatcagcatt ttgagctaat actgagggtc
     6241 atctgattgg acactgttta ttcggaaaga gggactttga cacgactttg gtcacagtcc
     6301 ctttttttat ttatgataga cggaaagcca atcattttat tattcatcaa aagagataga
     6361 atagataaaa gaggagaata atttattccg aaaagtgaaa acatataaca aaaaattaga
     6421 ggaaatcaaa tgaatgaaaa agaatgggat gaatttgctg aagaatatta tgaaatccag
     6481 caagaatcgc aagtaactat tgctgaagat gtaaaaaatt atctgaaaac ggagaaagtc
     6541 ctgcctgctg aaacagcagc agacgttgct ggaggatctg gcagatttct ttccttagca
     6601 aaagaaatta atcgctatga tttgatcgat ttttcttcag gaatgctaga aaatgcaaaa
     6661 aaagaagcag aaaaaaatga gttgccaaat gtttccttta tcaaacagtc gttagaagaa
     6721 tttatccaat caaatgagac atatgaaatg gtttttacag cagcaaatcc agcattggta
     6781 catcttattc aattagaaaa attgatgaaa aagtcaagca aatggtgcgt gataatcagg
     6841 gtagtggaat caatcgatga tgttttttat cctatcgaaa agcaactagg aatgatagaa
     6901 gaagatccta atacatcgcc agttgtaatg gatcaatttg aaacatactt aattgatgaa
     6961 ggattcaaag tgaagaaaaa agattttact tattttacac aggaatcaat tactgaagaa
     7021 ttgatgaagc tatactatga cgcgtacgca aaagatcctg ttgtgaccag gtacattcgc
     7081 aaactattca gtgaaaaacg agaaatcctt agtacgacta agctgaccta tagactgctc
     7141 ctttggtccg cagataaaaa aagaaccttt cacgactcgt gaagggttct ttttatgatt
     7201 ttattatatt ttgtagtaac gaatatcatt ttcgatcttt gtaatcgaaa aaggtacatc
     7261 tgaagtatat tctgcacatt ctccgtgttc aggaagcgtc tcactgaaaa tcgtttcata
     7321 ttcgtcaaca gtgatccgtg ttcgagaatc tagcatctct tgatgagatt gtgcgaagag
     7381 atattcttga tagttttctt ccagataacc tgtaaaaaat tcacttactg caccagaacc
     7441 gtagctgaat agaccgatgc gatctcctgg ctgtagtgat ttcgaatttt ccagtagaga
     7501 agttagcccc aggtataatg aaccagtgta aagattaccg attcgtcggc tgtaacggat
     7561 gctttcttca tagcgagcca taagacgttc ctgattttct tcgtctgttt ggtctaatac
     7621 gctttgcaat gccttttttc ccatcttagt atacggaata tggaaagcaa tcgcctgata
     7681 atcttcgagt cctcgacccg acaattcttt atgtcgattc caaacttttt ggaatgattc
     7741 gatatacgta gaattagata aaggaccatc aacaacagga aattcgctat aatctggacg
     7801 ccagaaatca tagatatctt ctgtcagaaa tacgctgtcg tcttcaatcg ataaaatacg
     7861 cgggttttga gtgatcatca tcgcaacagc accgacacct tgcgtcactt caccaccgct
     7921 tgccaagccg taacgagcaa tatcacttgc tatgactagt acttttcgtt ctggatgatt
     7981 tttgacatat tctttcgcca tgtgcaaagc tgcggtgcca ccgtagcaag cctcttttac
     8041 ttcaaaagaa cgagcaaaag attggatttt cagtaaatgg tggataatta ccgcactcgc
     8101 ttttgaatga tcaatcccgg attctgttcc gacgatgacc atgtcgatta gctcacggtc
     8161 tttttctgtt acgattttgc tggcagcatt tgctcctagt gtaatgatgt cttcatttgc
     8221 acgattgact gccatttggt cttgaccaat ccctatatgg tattttgcag gatcatcccc
     8281 acggctttct gccaactctg tcatatctaa atataaatta ggaataaaaa aggaaagacg
     8341 atcaatccct attttcattt caacacctct ttacttatga taaaaaactt actttactaa
     8401 ggtatcataa aaagattaaa agaaatataa aaaagagaat atttaaggat tgttaaaatt
     8461 taatcttaga aaaaaacaac tggaacaaga gctatttgtt tttacagcaa agaatggtat
     8521 atttttgtag gaggtggctt acttgaaaga agtcgttatg atagatgctg caagaacgcc
     8581 gataggaaag tatcgcggaa gtttaagtcc atttactgca gttgaattag gcacacttgt
     8641 gactaaagga ttattagata aaacaaaact gaaaaaagat aaaatcgatc aagtaatatt
     8701 cggaaatgtc ctgcaagctg gtaatggtca aaatgttgcc agacagattg ctttgaacag
     8761 cggtctccct gtagatgtcc cagcaatgac gatcaatgaa gtttgcggat ctggtatgaa
     8821 agcagtgatc ttagcacgcc agctgatcca attaggtgaa gcagaacttg tgatagccgg
     8881 cggaacagag agtatgtctc aagcacctat gctgaaaccg tatcagtcag aaacaaatga
     8941 atatggtgaa ccaatttcca gtatggtcaa cgacggattg actgacgcat tttcaaatgc
     9001 acatatggga ttaaccgcag agaaggttgc aacacaattt tctgtgagca gagaagaaca
     9061 ggatcgctat gccttgtcgt cccagttgaa agcagcacat gctgtcgaag ccggtgtatt
     9121 ttctgaggag atcatcccag tcaagatttc tgatgaagac gtgttatctg aggatgaagc
     9181 agttcgtgga aatagtacat tggaaaaact gggcacgtta cgtacagtat tctcagaaga
     9241 aggaactgta acagcaggaa atgcttcgcc attgaatgac ggtgcctctg tggtgatcct
     9301 tgcatccaaa gaatacgcag aaaataataa tctgccttat ttagcaacca tcaaagaagt
     9361 agcggaggtc ggtattgacc caagtatcat gggaatcgct ccaatcaaag ccattcaaaa
     9421 attgacagat agatcaggaa tgaatttatc aacaatcgat ctttttgaga tcaatgaagc
     9481 atttgcagct tcttctatcg tagttagcca agaactgcag ttagatgaag aaaaggtcaa
     9541 tatatatgga ggagcaatcg cattaggcca tccaattggt gcaagcggtg cacgtatctt
     9601 gactacatta gcttacggat tgcttcgtga acagaagaga tacggtattg cttcattatg
     9661 tattggtgga ggtttaggct tggcagtctt gttagaagcg aatatggagc aaacacataa
     9721 ggatgtgcaa aaaaaaaagt tttatcagct tacgccatct gaacggcgca gtcaattaat
     9781 agaaaaaaat gtattgacac aagaaactgc gttgattttt caggaacaaa cactttctga
     9841 agagctctcc gatcacatga tcgaaaacca agtgagtgaa gtggaaatcc caatgggcat
     9901 cgcgcagaat tttcaaatca atggtaagaa aaaatggatt ccgatggcaa cagaggaacc
     9961 atctgtcatt gcagctgcaa gtaatggtgc aaaaatctgt ggaaatatct gcgcagaaac
    10021 acctcagcgg ctgatgcgag ggcaaatcgt tctatcagga aaatcggagt atcaagcagt
    10081 gatcaatgca gttaatcatc gaaaagaaga gctgattctt tgtgcaaatg aaagttatcc
    10141 ttcaatcgtg aaacgcgggg gcggtgttca agatatctct actcgggaat tcatggggag
    10201 tttccatgca tacttatcta ttgatttttt agtggatgta aaagatgcaa tgggcgctaa
    10261 catgatcaac tcgattcttg agagtgtggc aaacaagtta cgggagtggt tccctgaaga
    10321 agagattcta ttcagtattt taagtaattt tgctacagaa tcattggctt ctgcctgttg
    10381 tgaaatccca ttcgaacgct tagggagaaa caaagaaatc ggtgaacaaa ttgccaaaaa
    10441 aatccaacag gcaggggaat atgcgaagct tgacccttac cgtgcagcaa cgcacaacaa
    10501 agggatcatg aatggtatag aagctgtagt ggcagctaca ggaaatgata cacgtgcggt
    10561 tagcgcttcg attcacgcct acgcggcaag aaatggatta taccaaggat taacagactg
    10621 gcagatcaaa ggggataaac tagttggaaa actaacggtg cctttggctg ttgccacagt
    10681 aggcggagct tccaatatcc tgccaaaagc aaaagcatct ttagctatgt tagatattga
    10741 ttcagccaag gaactagcac aagtaattgc tgcagtaggg ttagctcaaa acctggctgc
    10801 tttgcgtgca ttagttacag aaggaatcca aaaaggccac atgggacttc aagctcgttc
    10861 attagcgatc tcaattgggg ctattggtga ggaaatcgag caagttgcga aaaaattacg
    10921 tgaagcagaa aagatgaacc agcagacagc tatacaaata ttggaaaaaa tccgggaaaa
    10981 ataaaaaagc aatatcttta gaagaataaa gcaagattta cagttatttt atttactgca
    11041 aatcttgctt ttttctctat cagaaaatat gtttattatt agaatttttt atagttaagg
    11101 ttaggcatct taagaaatca ggcaactcca agatatcttc aggtagaaga gaagtcgcct
    11161 aacattgtag gatcataggt gatttgttgg acaggtcaag ctgatatttg agcctgatgt
    11221 tagaaggaat ttctttttac ttgctgtaga aattattata tgactaaaaa ggctgggatt
    11281 ttaaatccca gccttttatg acaaatagaa tttttatcga tcagtaatcg ctgtcgctgc
    11341 aaattgttcg atcaaaggaa tcaaagtcaa tttgactttg tatttccgtt cgagtgcttt
    11401 ttcgataacg aactcatttt cagtagtcat agaaatagtt gctaatttac gaggttcatc
    11461 agcatttttt tcattaataa ctacttcatg ttcattttgt tctgtgtaaa atttaggata
    11521 ctcagcaacg gcttttgaaa aatcagcaaa acttaaagcg gcattcgtat cagttgagcg
    11581 tgtattttca gttgtgtccg cttttggttt ttccgttttt tcttctggca cactgactgt
    11641 ttcttctgta actggtgtcg caacagcttg cgcagttggt tcatcgtttt tcaatcgttg
    11701 atcattccag taagacacga tttcaataag aagattgtca cggaatcgtt cgaaaatccc
    11761 gttttctcct gaacgaattc tctttaatac agtattgaag ttgtcatcga ttggcacgtt
    11821 gatccgtgta tcttcatttg ttttcccagc taatccgatc gttaagattt gacggttttt
    11881 gggatcaagc atgacttgta acggcaaacc atagcgtcgc aagctctctt cttctagaga
    11941 acggaataat tgtcctctta caccatccaa tgaaggacgg aattgattta ataatttttg
    12001 tttctgtttt ttcttcatat gttctctcct tcgctcatac cctttcgatt ataagaaaaa
    12061 aacagccaaa tgaaaaggag taatgcaaaa aaacttgcgt atacgcaaat tacaacagaa
    12121 aaatttgcgt attttcccgt tttttgaaag aaaaataaaa aatggaacgg attatgtata
    12181 tatacataat ccgttccatt ctttctattt tttcggtatc aaggcaaaaa caggtagttc
    12241 aggtgaataa atgacttcat gttcgtgcca gggtttgacc attagcgaat gatcgaaccg
    12301 ttttttcagt tcttcgatga tttgatcatg tgtccagttt cttgcaggaa aatgttggat
    12361 tttctctgca tcgatcaaaa agacaaaatc ggaatgaaaa gtctgggtaa cttcttccga
    12421 gagagaattc aagcgttcga ttggatccat aaaatcacct ttcgacttaa aattgggtag
    12481 tatctgggtc ttttgctttg ccgactacac catctaactg atcgatttgt ttcatttctt
    12541 cttctgttaa ttcaaaatca aataattcag tattttcttt gattctgctt ggtgtcactg
    12601 acttaggaag aggaaggaat tcgtgttgca gcgaccaacg caaagcaact tgtgcaatcg
    12661 tcttgtcatg tgcttcagcg atttgtttca tttcaggcac atcgaagatt ttaccagtgc
    12721 ctaatggact atatgcttcg aggatcatat catgtttttt tgcatactca actacagttg
    12781 gctgtaattc gcctggtgca aggaaaactt gattgaccat cggcataatt tttgctgttt
    12841 ttgctagtgt atctagatgg tggggtaaga aattgctcac accgattgct ttgattttac
    12901 ctgcttcata cagttcttca aatgctcgcc atgtatctgc atttgcttgt tcccaattat
    12961 cacgaaaagc aacagggttt ggccagtgga tcaaaaacag atctaaataa tctgtttgga
    13021 gcttcttcaa tgattcttca aaagaagaca tcacaagttc atagctgtgg tttgcattcc
    13081 ataattttgt tgtcaagaat atctcttctc taggaattcc actttcctta atcgcttggc
    13141 cgacactttc ttcattcttg tatccttggg cagtatcgat atggcgataa cctgcagcca
    13201 gcgcttcttt aacagaggaa acagcgacat ccccatcagg tgtttgccat gtgccgaatc
    13261 ctactaccgg gatttcgtaa ccatttaata gacgataagt gcttgttaat gaattcatac
    13321 tttcagctcc ttttttattc gttcaactat aagtgtagcg catttttcga aaaaaagaat
    13381 ccattttgtt tctactcttg aaatttttgt ttaaaagaaa atgattttga ttctggtatt
    13441 tttgattttt tttccgtaaa ctaagacaga agggaatgag aaaatggata tctatttaaa
    13501 aaaagcaatt ctgcatatta ttgacagaga aactggttct ccagtctttt cacaaaaaga
    13561 gctggatctg acaaaagaat atattcgtga ttttcttcaa aagaagatcc aaaaaatctc
    13621 ttctgctcaa acaaaaactg gacaactagc agaagaaagc atgatcgttg aatcacttaa
    13681 aatcgctcaa gaaaattttg tggaagcaag tgaagcaatc gttcagcggt ggttcgatat
    13741 ctaccaagaa agtgaagaag cacctagtgc agatgtattt gttgttttgt atgaattaga
    13801 tacagtgatg tacttatctt tattgaaagt caattatcgt gaggcttaca ctcactttgt
    13861 tgaagcagac gaagcaggga tcgacaaccg cttgattttg aatcgagcaa ttctaggggc
    13921 gaaaacacaa aaagcagatg aagcattcgc tgtgaatttg actgattgga cctacgaatt
    13981 aattgaaaaa aaatatgagt tttctggcaa aaaagagctt tatttttctg gaagagtgat
    14041 cgaaagtgtt cctgcacctt ctttagaaga aaatgtaaaa gtgatccaaa aagtagccaa
    14101 gcatcttgga aaaaaatttg agacagaaga atttgatatc atggctgatt tgaaagaagc
    14161 tgtctatgat acgatagaag aaaaaggtcg gttggatcat gagatgattg cggaaaaagt
    14221 cttcaaggaa aacatcacgg caaaaatggc ttttaaagaa gaagtacaag agcaaggatt
    14281 tgtcccagaa gcacctcctg taaaagaagt acaagaaatt tctgagaaaa aatttggaaa
    14341 acaaaaattc aagctatcaa acgggatcga actgatcgta ccagtagatg tatatcgcaa
    14401 cccagatttg attgaatttg tgaataatcc ggatggtacg atatccgtga tgatcaaaaa
    14461 tgtggatgaa gtattgaatc gtttataaaa atgactagaa cattaggtgt tcaagtacca
    14521 gtgatcagtt aaatgaattg tgtcaagaga aggatcggaa aagacgaata taacaaaaaa
    14581 agagcgtgag acaaaagtaa agaacacttt tgtctcacgc tctaaacacg tataaacggc
    14641 ggaagcagaa gcaactcctt cttatttctt ggagttaaac gcttctgtcc cagcctcttt
    14701 ttatcttctt aattgtcaaa ttaagttaga caaatcatca atacttacgt aactcaaaaa
    14761 tacttccaaa ggtgttcgat aattcagtga ttttctagga atattatttc gtttcgatgc
    14821 gacagattga ataaaagatt catctactga attgaaatcc atagatttca ataaaccatc
    14881 tctacgtaac aatccgttag aattctcgtt taggcctctt tgagacggcg ttcctggatc
    14941 agcgaaataa atggcaatat cattggcatt actgatctgt ttccaatttg aaaattcctt
    15001 tccacaatca aaagtgatgg atttgaatag atttttcggt acagattcaa accaatgatt
    15061 taatttgttt tcaatatcaa tcgcttgtct accacacggt ttcaatgtga tgataacttt
    15121 tgataatcgc tcaactaagg taattacagc acttttatgt ttcaaaccta cgatagtgtc
    15181 accttcaagg tgaccaaact catttgagaa ttggctataa tctttttcac gttcatgaat
    15241 agagcgacgg aaagcttgtt ttccacgtct ttcttgatgt ccatttggtt tacgcttgcc
    15301 tttcatcggt aagtcagaag gattaaatag cccctttttg aacatacgat aaatggtacg
    15361 agcagaacaa cgaataggaa acgctgcacg accaacaatc acatcgggtg tccatccttg
    15421 aacaaccttt ctttgaatat attctgattg ttcctcaggt aaaacaagcg ggcgtctacc
    15481 acagtttgat ttgtttttct tatactgttg atagtactct aaggctgatt ttccttgctt
    15541 gaagaacagg tatactttat ggatcgtttg tcttgaacga ttcaagaaat gcgcagtttt
    15601 cgcaacagat tgatttattt tgaaataaga ctctatcatt acaagttcat ccgttgtaag
    15661 atgggtatag gtcatttgta ctcactcctt ataattcttt ggacggaact attttgagtg
    15721 tagcacaaat gactttttta gttgtctagc ttaattttac aatcggcgtc taataaaatt
    15781 ttaagaccat ttactaatta tcgatttttt ctgccgcatt tttaggcact tcagaagcct
    15841 ttatttcttc ccagcttaat acacctttac gaggattgac tttgagttta agatacgcat
    15901 tcatctttaa tggatgttct ctttcttcgc gaagcgtcac ctgttttttt tcaccatctt
    15961 tattataagc cgcttgcttg taggtataag tcgtgaattt ctctccgtta tctgcttggg
    16021 tagctgacat ttcgccattc gtcgtgattt ttgtataata agcttcgccg ccgtaaaaat
    16081 aatgataagc tgcaaaactt ccgccgagaa atatgcctaa aacgacaagt acgccaatta
    16141 attttttcat gtacttcacc tctttcctta ttattaacga aatagaagat ttcgtctatt
    16201 gaaagttgtt ggcaacagct gaattttaaa cttttcctca ttttgttctt attgcttcaa
    16261 aagaaagtta aggactatct tgaagttttt ctcaaaaaac acattttttt atttataaaa
    16321 ggtacttttt tcgcgtataa gacaagcgag tgctcttagt tgactttgac caatattgac
    16381 gtataataag cttagttcga atcttacaaa aagtaagtcg gacgtattct ttttgattta
    16441 gtcaaaaaaa gactataata aaaaggtgag agctgaaatt tttcagtgat ctatattatt
    16501 taggaggttt gtaaattatg gcaaaagaac attatgacag aagtaaacca cacgttaaca
    16561 ttggtacgat tggacacgtt gaccatggga aaactacttt aactgctgcg atcactacag
    16621 tattaggcaa aaaaggccta gcaaatcctc aagactatgc tagtattgat gcagctccag
    16681 aagaacgtga acgtgggatt acgatcaata ccgcacacgt agaatatgaa acagaaaaac
    16741 gccactacgc gcatattgat gcaccaggac acgcggacta tgtgaaaaac atgattacag
    16801 gggcagcaca aatggatggt gcaatcttag ttgtttctgc aactgacggt ccgatgcctc
    16861 aaacacgtga acacatttta ttgtcacgcc aagttggtgt aaaatacctg attgttttct
    16921 tgaacaaagt tgatttagtc gatgatgaag aattgatcga tttggtagaa atggaagttc
    16981 gcgagttatt gagcgaatat ggtttcccag gcgatgacac tcctgtgatc aaaggttccg
    17041 cattaaaagc attgcaaggc gatccagatg ctgaagctgc tattatggaa ttgatggata
    17101 cagtagatga atatatccca acaccagaac gtgatacaga taaaccatta ctattgccag
    17161 tggaagacgt cttctcaatt acaggtcgag gaactgttgc ctcaggtcgt attgatcgtg
    17221 gtgctgttcg tgtcggtgat gaggtagaga tcgtagggat caaacctgaa acacaaaaag
    17281 cagttgtaac aggtgtagaa atgttccgta aaacgttaga ttacggggaa gctggggata
    17341 acgtaggcgt gttgttacgg gggatccaac gtgacgatat cgaacgtgga caagtgcttg
    17401 ctaaaccagg ttccattact ccacatacaa aattcaaagc agaagtgtac gtgttgacaa
    17461 aagaagaagg tggacgtcat actccattct tcaacaacta tcgtccacaa ttctacttcc
    17521 gcacaactga tgttacagga acaatcacat tgccagaaga tacagaaatg gtcatgcctg
    17581 gtgacaacgt gacgattgat gttgacttga tccatccaat cgctgttgaa aacggaacga
    17641 cattctcaat tcgtgaaggc ggacggacag tgggttcagg tatcgttaca gagatcgaag
    17701 cataagaaac gcgactcgaa tattttggta atgaaaaatg tttaaaataa aagagcggtc
    17761 caaacaggat ttctgtttgg accgctcttt gttcttcaat tgtataagaa gagattgtag
    17821 aagcatgaac tttcgtttta cttcagtctc ttttattcat catgagagtg ttcatctatc
    17881 ggtatgcagt ttttaatact ttcttcgtat ccattttttc aaaccactta ttctaccttg
    17941 tgtctgctca actggcgcat tatcaataat cagcaaagca atcataacat atgcaatcca
    18001 actatctcta gaatatagag tataacgtga gacccagttt gtagcgtact tgcttttata
    18061 ttctcttaat ccatggaaag aataaaaatg agaaccaaac tcgtaaacca agtatgcaat
    18121 cctttcctgt aaaaaactct ttctggaagt tccgacattt gaaagagggg ccatccctaa
    18181 attgaaccat tggatatgtt cttctttcat ataggcaaac aaatgcaaga acaagaaatc
    18241 catactgcca gaaggtgctt ttttaggatc atatcgcatc agatcaatcg ttcctacttt
    18301 attgttcgtg taagtaggca tgatcgttgc aaaagcgaca atttcttctt gggtattttt
    18361 gacaactgca ataggcgctc tttgtagata atcttcagag aaaaagccta aagaaaaccc
    18421 tttttccttt cgtgaaccca accaattatc agagatattt ttgaaagtac tcatttgctc
    18481 agtagaaaat ggtggttgta agacatcaaa tgtaaatcct tctcgttcga tccgattcaa
    18541 gacagcacga gtgcccttca tttttttccc tgaagttgta aaactattca ggtctacata
    18601 agcttcttcc cccatcttaa tgaaatcgta gccgaattca tgcaaaatca taacaatctc
    18661 ttcgcttgtt tcgtagaaaa ctggtaaata gcatagtcga tctgtttctt cgataaaagc
    18721 ttcgattgct tctggaaaat cttctttctt accagaagga tcacccatta caatacattt
    18781 attattgaag caagcgaatt ggagaagaac agttggttca ccgtcttttt cataggcaaa
    18841 catccgctta tcttttaaga agatcaattg actatcggag tttcctccat aagttgtaag
    18901 gatcttcagg gccttttctt cattaaaggc ttcgccaatc tgtttctttt ctccttgaag
    18961 gaaatgaaca aatagaacga tcatgaaact aacagcgatg atggccaaca atcccgaaaa
    19021 ccaaatcttt tcagaaggaa ataagaaaaa ggaaataaaa tggtgacgcc gatgagggaa
    19081 atccggcaga ttgtataccc caataacgat gtaaagcaag gacagtgcac caataatgat
    19141 tccatcgatc gtacgccact cccatgaata gatcaattgt tcccgaaata attcgttttt
    19201 agaagcaaga atgatcagaa gcagaataga caagaaaacc accggtgtga aactaaaatc
    19261 acttaataaa acataaagta aagctagaac aatcaagaag attgtaggca aatatgctcg
    19321 tttcacacgt gctgcgatcc ctctgcccat aatgattaaa agaaatccca atagtatact
    19381 aggaaattgg ataataaaat gaaatttcaa tgggttcaaa ctatgaagcc agcgaaactc
    19441 tgtaaaagct tgcgggatag tggcagaaag tactagcatg attccagaaa agtataataa
    19501 gacaaccacg attttatgcg caatttctgt tgctaattgt ttagggatac cagaataacg
    19561 ctgatcaaaa gtggaaccga tatttttgaa gaaaaagacg attccaatca aaaacggaat
    19621 gatgtagtag aacaggcgat agagcaagat ccacacaacg actatttctc ttggcacacc
    19681 aatagcggac aacccgataa tcatcattac atcgaaactc ccaatttctc ctggaatcat
    19741 agacacgatt cctatcactg aagcagcaat gaataacgga attgtttgcc acagatcaat
    19801 ccggatttcc attaaataac caacagaaag gaaactaaac aggacaccgg tccattccaa
    19861 caatgaaact agcaatagct gtccttgagt tttaagtgag gtaccaccaa ggaatccttt
    19921 ctttttgaaa gtagtaaata aaaagacgac aggaaaatat agaccgccgc cgatcaacca
    19981 tatccaatat tgcttcaaaa aaggagcaac tggcgtgaag actacaagta aaaaagaaag
    20041 cagactgtaa atagaaagtc cagccatcaa aaacaagaaa actttcgata atgcttggat
    20101 cacgtttctg ctctctttct tttgtccata tagttcagag cgaagcccca cactaacaaa
    20161 cccgccgaaa ccggcaatat tgttgattgt attgatcagc cagcttgtct caaacaagta
    20221 acgaggattc tgcttttgtt caagcatccg attcaaaata atatcataac caatcatagg
    20281 taacacagag acaagaccaa tcaacagcat aagtccgctt ttccatacag gtatagtggc
    20341 aaacgtttct cctaattgct ggatagatag agttttaccg atggacatca attcaccgac
    20401 aataatgaca atgacagaaa tcaaaaagat tgttttgaac agtcctaggt ggtttttcag
    20461 ccattgtatg gtatttttta acaaataaat caccttctat tcctaatagt tatgtttcag
    20521 aaagaaattg aagaacttct cgattgaagc gttcaggatc ttttctagct aattcatgtc
    20581 cttgttcttt cacaagcaca aaggaagctt ttggtatagt tttagctata tacaaagaat
    20641 gttttagctt gattacatct ttttttccca cgatgatcaa agtgggggag ttgatttttt
    20701 ttaaatcatt ttctgtaagc ccgatgtcat gcagcaaaag tttgataact aaaagatttt
    20761 tgcgaagact tgggcgaaat aaagagagta accataccca tgcataatga atattactga
    20821 tgactctggc agaaaaacga acgcctttaa caagcgtgtt tccagaattt aaaatcaatc
    20881 gatgaacttt tttagggaag ctgctggcaa ataccagtgc tagatttgct ccatcactaa
    20941 atccaagaaa atctgcctga tcgatttttt ccagcaacat gatcgtattc agatcctcgg
    21001 ccattaactg aaaattcaac atagatgctt cgtttgtcga acgaccatgt cctcggctat
    21061 ctactagata cacggtatag tagcgttcga gtacagggac ctgttctgaa aaaaagcggc
    21121 cgctgccgtc attgccatgc agtaaaaaga gagggaagcc ttgaccgctc ttttcatagt
    21181 aaatttcgct cccatctggc atttttgcat atttcttttc ttttttcaca taatcaccta
    21241 ctgtgtaaag tataacgatt atatcagtca ttgggcaatt gtttttactg aaaaacaacg
    21301 atcattttcg taagatgaca aaaaatacag gaaaattcat tttttcttaa ggcgtacaca
    21361 gaaatcaagg aagaaatagc caagaagata aagaaatagt aagataaaaa aagatgtcaa
    21421 aataactagg tgatgaaatg aagcgaaaac gattatctat tatccgtatt cttttttaca
    21481 tgatcattct gacggttatt ggtgcggtgt tgtttttagg aggaagaact tatcgttcgg
    21541 taaaacgagt ggaaagctat caaatagaaa taacaacagc tgcaaaaaat tatcatatgg
    21601 aaaactacga gaatttgatc aaggcgataa tattgaccga atcaaaagga aaagggacag
    21661 atctcatgcg gagctcggaa agtctgcatg gagaagctga gatcattgat aatccagctg
    21721 acagtattga tcaaggtgtc aaatatttgg cggaaatgat agtagaagca aagaaacaag
    21781 gatgcgattt atggacagct gtccaagcat ataattttgg gaaagattat attgcctatg
    21841 taaaaaatca tggcggagaa aacacagtag aattagcaga agcgtattct aaagatgtgc
    21901 tgagcccact tttaggaaat gaggaaggga aacaataccg atattggcgg atccagtcct
    21961 tgctttacaa tggcggctat ctctatcata atggaggtaa catgttttat cctgatattg
    22021 tcaaaatgaa tgaaaaaata atagagacct atgaaaaagt ctttaagtaa aatagcagga
    22081 aatgttcaat catgaataaa attaaatgaa agaaggagtg cgcaaatagt ggaaaaaagg
    22141 caaaaaatgg aaaatcaaga agtggggtac acaaccaaag actggatgtt acggtttgtg
    22201 aagggaatgt ttatcggttc aggatttatc ttgccaggag tcagcggtgg tgcattagca
    22261 gctgtctttg gcatgtatga gcggctgatt tcttttttag cccaccttac aaaaaatttc
    22321 aaagaaaatg ttttgttttt tctgcctgtt ggtctaggcg gagtgacagg catctttcta
    22381 ctttcttttt tagtcagttt tttattaggt gcgtatgaaa caacgatatt atggtttttt
    22441 gtcggatgta tcgctggaac tgttcctgcg ttatggaaag aagcagggaa aaaaggaaga
    22501 gatacttctg atgtgatcat catggttgtt acttttgttc tggcttattt gtttttatta
    22561 tacggcgctc aattatttga cgggcaagtc gatcagaatt ttggaacatg gctgattgcc
    22621 ggcggattga ttggtttggg tatgatcgtc ccaggattga gcccttctaa ttttttggtg
    22681 tatatgggat tgtataaagc gatggctgac ggatttaaag aagtacgact tgaagtgatt
    22741 gtgccgatcg gaattggtgg gattctttgt gttcttggat tgtcaaaaat catggattac
    22801 attttctcaa aggcatatag caagctattc catttcattt taggtgtagt ttttgcttca
    22861 acgattatga tcattcctac cgattacgcg ggattgggag ttgctggggt actagcttgt
    22921 cctgttcttt ttatagccgg tacagcacta ggttggtgga tgagccgttt ggaggaacaa
    22981 tataagtaaa gatagattga taataaaaac agcacacggg tgattcaaac aaaaaggttg
    23041 gcatcttttt tgtaaaatca ttcgtgtgtt tttctataaa ttttataaaa acaagttgtt
    23101 tttaatcttg gaacacgcta gacttaaaca cgtgattatt tttgaaagtt ggcggaaaat
    23161 ggagaaaaag aaaatgaatg gacttacaca gcaagaggta gttcagaaaa tggcttctgg
    23221 ccagcaaaat gactaccagg aagatgcatc aaaaagtaca aaacaaatat tcagcgataa
    23281 tatattgacg ttattcaatt ttctgaactt tggtattggg atttgtctgt tatttgtagg
    23341 tgcgtattcc aacatggcgt atttagcaat tattgtcgtc aatatcgtta ttggaattta
    23401 tcaagaaata catgcaagaa atcttgtacg gaaattatcg attgtttccc aatcagaagt
    23461 actagtgatc cgggacggta aagaacaatc gatttctact aaagagctgg tattaggaga
    23521 tttggtaaaa atcggagcag gagaacagat accagccgat ttacaggtta tatctggacg
    23581 ggcagaagca aatgaagctc ttttgacagg cgaatctgat ttgattgtca aagaaactgg
    23641 agctgaattg ctttctggaa gctttttgac aagcggttct gtcatggctg aagttatccg
    23701 agtaggtgca gataattatg ctgtccgctt gactagcgag gcaaagactc acaaagctat
    23761 tcgttctgaa cttgtagatt cgattcgcaa agtatccaaa ttcactagtt tcgtgattat
    23821 tcctttgggg atcatactat ttttggaagc actgttcatc cgcgatgctt ctatcaaaat
    23881 ttctgttatt gcatctgcag cagctttgtt aggcatgctt ccaaagggtt tggtattgct
    23941 aataagtatt gcattaacga caggggtaac caaactggca aaaaaacgaa tccttgttca
    24001 agacatgtat tcaattgaaa cgctggccca tgtcgataca ttatgcttgg ataaaacagg
    24061 gaccattact gaagggaaaa tgagtatcca gcgggtagaa gcactacatc cgctgtacga
    24121 gaaagccatc ccagaaatta tggggacgta tctggcagaa agcagtgata acaacatcac
    24181 tatgcgggct atgagagatt attttgagct ttctaatcgg tatgatgtga caaacaaagt
    24241 cgcattttct tctgatcgca aatggggcgc gatggaattt ccagaactgg gagtcgtgta
    24301 cgtaggagcg cctgaacgtt tggtggaaga agatcggctt ccggacagtc taaaaacagc
    24361 ccaagcgaat ggctatcgcg tacttatgtt ggggatcgct ccaaatcagc aattgaacga
    24421 agaaaaacca gcatttgttg agccggttgc tctgtttgaa atcgatgatc caatccgaaa
    24481 aaacgctcaa gaaacactag cttatcttca tgaggaaggt gtggatctga aagtgatttc
    24541 tggagacaat ccttttactg tctccaatat cgctagacgt gcaggattac cgaattatga
    24601 tgcgtatgtc gatctttctc aaattactga agaaatggaa gtgcgagaag ctgctcatcg
    24661 ctatacggtt tttggacgag tgagtccgca gcaaaagaaa ttgctggtaa atgaattgaa
    24721 agaaagcggc agaacggttg caatgacagg cgacggtgtg aatgatgttt tggcgttaag
    24781 agaagcagat tgcagcattg ctatggcaga aggtgatgga gcaacacgtc agattgcgaa
    24841 tctggtattg ttggactctg attttactac attgccagaa gtcctgtttg aaggacgccg
    24901 agtggtcaac aatgtgacga aagtctcagg catctttttt atcaaaacga tttattcatt
    24961 tattttatcg attatatgtg ccgttacagc aattggattt ccgtttatcc ctatccaaat
    25021 cacgctgatt gatttagcga ttgaagggta tccttccttc tttttatctt ttgaacaaga
    25081 taaaagaaaa atcacttacc gttatttgcc tacagcactt attaatgctt taccaaatgc
    25141 cttgcttgta gtagtgaata tcattgcggt gtatctactt ggaaaaacat tcgcatgggg
    25201 aaatgctgaa actactactt tgatgtatta cttgctgatt gggatcagtt gcatggcagt
    25261 tgtaaaagct tgttatccct tcaacccatt gcgcatcttc ctagcagtaa cgacgatcgt
    25321 agggatatat gtagctgcaa tgctgttcca tggaattttg gaagtaaact tagggttggg
    25381 agagagcgta ggatacttct ttgtattcat gctcgtaaat attgttcttc gagtattgta
    25441 ctggaaggct gatattcaaa atcagttact gaaaagagta gcaaattgat gcttaatgag
    25501 atagaaatgt gttatacttg aaaaagcaat gaaatatgat acaatcaaac atgtataatt
    25561 gtgtccttta aaatcgcact gatttcagtt agtgcgattt tttaccggtt attctcctga
    25621 aatatcttct gttaaaccca aaagatatca atagagcagg gggtgaaaaa atggctcaac
    25681 ggattcctca agaggttatc gaaacagtac gcagtcaaac gaatatcgtt gaggtgattg
    25741 gacaatatgt ccagttgaaa aagtctggta aaaattactt ggggctgtgt ccttttcatg
    25801 aagaacgtac accgtctttt tctgttgcag aagacaagca gatttttcat tgctttggtt
    25861 gtggtaaagg cggaaacgtg tttacttttc ttcaagaact agaaggtcta agttttccag
    25921 aagcagtggt aaaagtggca gacttcgaac agataccgtt agaagatcaa tggcgtcagc
    25981 gtactatagc tgtccaaaat cctgaatctg ctacggggaa actgattgct gctcatgaaa
    26041 aagcagcgga aatctatcat cacatgctat tgcatacaaa agctggacag ccagctttag
    26101 aatatttgca aagtcgtggg ttgtctttag aattaattga agaattcaac ataggttttg
    26161 cacctaatga gcgttctttt cttcagcaag tattcaagaa tgaatcaatt tcaaatgaat
    26221 tgttagaacg ctctggattg tttgtcacgc atgatgatgg ccgtatgtct gatcgttttt
    26281 atcaaagagt gatgtttcca cttcgtaatt ctcaaggcca gacgatcggt ttttcaggac
    26341 gctggcttgc acctgaaaaa gggcaggaaa aagatcagcc caaatacttg aatagtccag
    26401 aaacagaact gttcaataaa agacaagttt tatttaatct tgataaagca agaagcgata
    26461 tccggaaaaa cggagaaatt ttgttgttcg aagggtttat ggatgtgatt gctgcatggc
    26521 aggctggtat caaaactgga ttagcttcta tggggacaag tctaacagct caacagatcc
    26581 aacaaatgga aaagctgacg aaagaattgg tcttttgcta tgacggagac aacgcaggtt
    26641 ttgaagcaac caatcgaggg attgaattgc ttcggcaaaa cagtcgatta gcactttctg
    26701 tcgtagtcgt tccagaaaag cttgatcctg atgaatatct ccgtaagtat ggagaagcat
    26761 ctttccaaga attagtggct catgggcgcg aaacagtctt tacttttaaa tcacgttatt
    26821 taaaacaagg gaaaaattta gataatgaaa aagacaagat cgaatacctc gaagaattac
    26881 tagttgaact tagccgagtt gtttcaccaa tcgaacaaga tatgtatcta tctcaactgt
    26941 caacagagtt tcagatcggc agagagacga tacaaaaaca actgcgcgat cttcgaagga
    27001 caaatcagca aaatcgtcaa gaacctcagg aaagtcaaca cactcaggtt acgagacaag
    27061 aaactgcacg gaaaaagaga cctttgacgc aagtagaaaa ggcagagcag attctattat
    27121 atcgtgcatt taaagaagtt tctgtccgta atattttaaa agaacgagaa tttcagttta
    27181 ttcatgatgc atatgcagaa gtttattttt tattcgatgc atatgtctca caacattatg
    27241 aattcaacct tgcagagttt ttagactttt tgcaagatga aaatttaagg cggttggtgg
    27301 tggaaatcga atatttaccg gtggcagaag aaagttcgcc acgagaaatc caagacttgc
    27361 tagatgtgat cagcaaatct ggcttagctg atgaaataac attaaaaaaa caaatgcagc
    27421 aagaagccag acgaactgga aacaaacagc ttgagcttga attgacgatt gaaatcatca
    27481 atttaacgaa acagttaaaa caagccaaat agctactcaa ggggggcctt cttttatggc
    27541 aaatggaaca gataaaaaaa cgtatgaagc agcagtagca gctttcatca aagaaaacaa
    27601 acccaaacga caagttgtat atgatgattt atccaatcag cttgctacac cattcacttt
    27661 gaatgcagat gaaatggaca aattgatcca aaagattgaa gacgcaggta tcagtgtggt
    27721 ggatgaaaat ggtgatccat caattcacag cttgaagagt gctgagaaaa aagctgaaca
    27781 agcaaaaaca gaagatcttt ctgcgccaac cggtgtaaaa atcaatgacc cggttcgtat
    27841 gtatctgaaa gaaattggcc gtgtctccct tttaactgcg gaagaagaag tagcgttagc
    27901 attgaaaatc gaagaaggcg accaagaagc gaaacagcgt ctggcagaag caaaccttcg
    27961 tttagtagta agtatcgcta aacgttatgt aggacgaggc atgcagttcc ttgacttgat
    28021 ccaagaagga aacatgggac tgatgaaggc agttgaaaaa tttgactacc gcaaaggatt
    28081 taagttttca acctatgcta catggtggat tcgtcaagcc atcactcgag caatcgctga
    28141 ccaagcacgt acgatccgta ttccagttca tatggttgaa acaattaata aattgatacg
    28201 tatccaacgt caattgctgc aagaccttgg aagagaacct acgccagaag aaatcggtgc
    28261 ggaaatggat cttccaacag aaaaagtccg agaaatcttg aaaatcgcgc aagaacctgt
    28321 ttcccttgaa acgccaatcg gtgaagaaga tgactctcac ttaggtgatt tcatagaaga
    28381 ccaggaagca acaagtccag cagaacacgc agcttatgag ttactaaaag aacaattgga
    28441 agatgtacta gatacattga ctgatcggga agagaatgtc cttcgcttac gttttggttt
    28501 agatgatggc cggacgagaa cattggaaga agtagggaaa gtgtttggtg ttactcggga
    28561 acgtattcgt cagatcgagg ctaaagcatt aagaaaattg cgccatcctt ctcgttcaaa
    28621 acaattaaaa gatttcttag aataagcgtg gactattgac cagaagagaa atcagtaaaa
    28681 ctgtttggtt tattttaaaa gaaaaaa
//
LOCUS       DAZULR010000035        28600 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.035, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000035 DAZULR010000000
VERSION     DAZULR010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28600
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.035"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            234..1874
                     /locus_tag="ACG8ZV_001791"
     CDS             234..1874
                     /locus_tag="ACG8ZV_001791"
                     /EC_number="4.1.1.101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043883 - malolactic enzyme activity
                     [Evidence IEA];
                     GO_process: GO:0043464 - malolactic fermentation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malolactic enzyme"
                     /protein_id="HFS4997125.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAVFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            2028..3350
                     /locus_tag="ACG8ZV_001792"
     CDS             2028..3350
                     /locus_tag="ACG8ZV_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HFS4997126.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(3412..3843)
                     /locus_tag="ACG8ZV_001793"
     CDS             complement(3412..3843)
                     /locus_tag="ACG8ZV_001793"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4997127.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(3907..4743)
                     /locus_tag="ACG8ZV_001794"
     CDS             complement(3907..4743)
                     /locus_tag="ACG8ZV_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HFS4997128.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQAIVIVVLLINLYNAFVILQTLEGSGFKQVKITEKSF
                     FK"
     gene            complement(4933..5235)
                     /locus_tag="ACG8ZV_001795"
     CDS             complement(4933..5235)
                     /locus_tag="ACG8ZV_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HFS4997129.1"
                     /translation="MTEHNHSHEHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEE"
     gene            complement(5261..5692)
                     /gene="ruvX"
                     /locus_tag="ACG8ZV_001796"
     CDS             complement(5261..5692)
                     /gene="ruvX"
                     /locus_tag="ACG8ZV_001796"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HFS4997130.1"
                     /translation="MRVMGLDVGSKTVGVAVSDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(5689..5955)
                     /locus_tag="ACG8ZV_001797"
     CDS             complement(5689..5955)
                     /locus_tag="ACG8ZV_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HFS4997131.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(6209..6934)
                     /locus_tag="ACG8ZV_001798"
     CDS             complement(6209..6934)
                     /locus_tag="ACG8ZV_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HFS4997132.1"
                     /translation="MSKKTTKAIVGIVAAVIAGALGISTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(7300..7370)
                     /locus_tag="ACG8ZV_001799"
     tRNA            complement(7300..7370)
                     /locus_tag="ACG8ZV_001799"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7336..7338),aa:Gly,seq:ccc)
     gene            7487..8239
                     /locus_tag="ACG8ZV_001800"
     CDS             7487..8239
                     /locus_tag="ACG8ZV_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFS4997133.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            8255..8734
                     /locus_tag="ACG8ZV_001801"
     CDS             8255..8734
                     /locus_tag="ACG8ZV_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFS4997134.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(8985..10565)
                     /locus_tag="ACG8ZV_001802"
     CDS             complement(8985..10565)
                     /locus_tag="ACG8ZV_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HFS4997135.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(10558..11301)
                     /locus_tag="ACG8ZV_001803"
     CDS             complement(10558..11301)
                     /locus_tag="ACG8ZV_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4997136.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(11477..12253)
                     /locus_tag="ACG8ZV_001804"
     CDS             complement(11477..12253)
                     /locus_tag="ACG8ZV_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFS4997137.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(12501..13337)
                     /locus_tag="ACG8ZV_001805"
     CDS             complement(12501..13337)
                     /locus_tag="ACG8ZV_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HFS4997138.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(13348..14277)
                     /locus_tag="ACG8ZV_001806"
     CDS             complement(13348..14277)
                     /locus_tag="ACG8ZV_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HFS4997139.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            14469..14822
                     /locus_tag="ACG8ZV_001807"
     CDS             14469..14822
                     /locus_tag="ACG8ZV_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HFS4997140.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(14896..15552)
                     /locus_tag="ACG8ZV_001808"
     CDS             complement(14896..15552)
                     /locus_tag="ACG8ZV_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HFS4997141.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            15778..17712
                     /locus_tag="ACG8ZV_001809"
     CDS             15778..17712
                     /locus_tag="ACG8ZV_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFS4997142.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(17798..19021)
                     /locus_tag="ACG8ZV_001810"
     CDS             complement(17798..19021)
                     /locus_tag="ACG8ZV_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFS4997143.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(19015..20886)
                     /locus_tag="ACG8ZV_001811"
     CDS             complement(19015..20886)
                     /locus_tag="ACG8ZV_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HFS4997144.1"
                     /translation="MKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQIDYIHQGVG
                     YGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYWGEIHERDQR
                     MVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQFFKIIVGTII
                     QKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYGLIYSVLEPE
                     KPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAMLWADLLPFKL
                     GEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLWLNKIFLLLA
                     LPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPNFHTLTNEKY
                     LKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKTYGQFIVRNN
                     VRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLYETGFAIECS
                     PEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLMTWENTFIPG
                     LEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKNNKKRLKLC"
     gene            complement(20907..22025)
                     /locus_tag="ACG8ZV_001812"
     CDS             complement(20907..22025)
                     /locus_tag="ACG8ZV_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFS4997145.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(22108..22941)
                     /locus_tag="ACG8ZV_001813"
     CDS             complement(22108..22941)
                     /locus_tag="ACG8ZV_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4997146.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVSATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(22934..23851)
                     /locus_tag="ACG8ZV_001814"
     CDS             complement(22934..23851)
                     /locus_tag="ACG8ZV_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4997147.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(24078..25202)
                     /locus_tag="ACG8ZV_001815"
     CDS             complement(24078..25202)
                     /locus_tag="ACG8ZV_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFS4997148.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            25385..26293
                     /locus_tag="ACG8ZV_001816"
     CDS             25385..26293
                     /locus_tag="ACG8ZV_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFS4997149.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            26434..28047
                     /locus_tag="ACG8ZV_001817"
     CDS             26434..28047
                     /locus_tag="ACG8ZV_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFS4997150.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNNYTSARILAGLGIKAILIEE"
BASE COUNT         8893 a         5621 c         4868 g         9218 t
ORIGIN      
        1 tatttatcta tctaacatat cctttattct tctacttttc tttctttagc atataagaga
       61 tacgcatagt aatcaagcaa ggattgttga tataaaaaga acaaataccg ctattttgat
      121 ttcttttgac tctattactc atataaataa aatttattat acctgctctt tttgactata
      181 tcctcatctg actcctatac ttcgtttgta ttaaaactta ggaggaatca ttcatgctta
      241 cagggctaaa cttattaaat aatccttttc taaataaagg aacagctttt acaaaagaag
      301 aacgggcaaa atacggaatc actggtatgc ttccaagtac tgtccaaaca ttggaacaac
      361 aatctgtcca agcttacggt caatacttaa gcaaacagac cgatttggaa aaacgtatct
      421 tcttaatgaa tctattcaat acgaaccgga cattgtttta taaattgatg ggcgaacatt
      481 tagttgaatt catgcctgtc gtttatgatc ctgtcgttgc ggattcaatc gaacaataca
      541 acgaaatttt cttgaaacca caagatgctg tatttctttc aatcgacgaa ccagaaaata
      601 tcaaagcaag tttgaaaaac gcagcagatg gacgcgacat tcgtttgatc gttgtgacag
      661 atgcagaagg aatcttaggt atgggtgact ggggtgtgaa cggtgttgac atcgctatcg
      721 gtaaattgat ggtctacact gccgcggctg gtatcaatcc tgcacaagtc ttgcctgtat
      781 caatcgacgc tggtactaat aacgaagaat tattgaataa tccattatac ttagggaatc
      841 gtcatgctcg tgtagaaggc gaaacttact acgaattcat tgatcaattc gttcaatcag
      901 ctactgaatt attcccagaa ttgttattac attgggaaga ttttggacga ggaaatgctg
      961 caacgatctt agaaaaatac gaagataaaa tcactacttt caatgatgat atccaaggca
     1021 caggaatcgt tgtactagct ggtgtattag gtggattgaa tatatcaggt gagcaattga
     1081 aagatcaaac gatcttgaca tttggtgctg gtactgctgg tgtaggtatc gcaaacatcc
     1141 ttttagatga aatgatccgt caaggtgtac ctgaagaaga agcacgccaa catttctatc
     1201 aagtagataa acagggttta ttgtttgaag atacaaaagg attgactcct ggtcaaatcc
     1261 cattcgctcg taaacgctca gaattcacta atgctgatga attgacaaac ttagaagcag
     1321 ttgtaaaagc aatccatcca acgatcatga tcggtacttc tacccaacct ggagcattca
     1381 ctgaagaaat cgtgaaagaa atggcggctc ataccccacg tccaatcatc atgcctttgt
     1441 ctaatccaac aaaattggca gaagcaaaag caaaagattt gattgaatgg acggacggaa
     1501 aagctttagt tggaacaggt atccctgctg ctgatgtgga atataacggt gtaacttacc
     1561 aaatcggtca agcaaataat gcgttgatgt acccaggttt agggcttggt ttgattgctt
     1621 caacagctac acgagtaaat gctgaaatca tttctcaagc tagtcgagca ttaggcggaa
     1681 tcgttgatgt aacaaaacca ggagcagcta tcttgcctcc agtagcaaaa atcactgaat
     1741 tctctcaaac gattgctgaa actgtcgcaa aatcagttgt tgcacaaaaa ttgaatcgtg
     1801 aagaaatcac ggatatcaaa gaagctgttg aatctgctaa atgggttcct gaatataaat
     1861 ctttagaaga ttaagattgt tatagtaaaa gaacatacag aaactttgta tgacgtctaa
     1921 aaagaaaaaa gcgactgcgg caaaacagca gccagccaac tactgctctt ttgccgcttc
     1981 tctttggctt ttttcatacg atacagaata agaaaggatc tgtaaaaatg gcacaaaaaa
     2041 caacaaccgc aactgcagtt gaggaaaaga aaaaagaagg gttttggtca acaaaaatta
     2101 ccggcgtaag tttgcccctt tatttgatca tggtccttgt cctgatcatt gcaatggctt
     2161 taggaaaatt accgacgaat atgattggcc caatcgctgt tttggtcatt ttcggtaatt
     2221 tatttcattt tatcggaaca aaaatcccta tagtcaaaag ttatttaggt ggtggctccg
     2281 tttttgcgat ctttgcctct gccgcgattg ctacatttgg gatcttacct gagtatgtag
     2341 taaaatccac agaaaacttt gtcagcaata tgggcttttt agacttttat attgctgcct
     2401 tgattactgg tagcatcctt ggtatgaacc gtaatctatt gatgaaagct tctgttcgtt
     2461 ttattcccgt tgcacttatt tcaatggtcg tctccttttt tgccgtagga ctcgtaggta
     2521 tgcttatcgg aaatggtttt gcaaattccg ttttatatat ctcattgccc gcaatggctg
     2581 gtggtgttgg agccggagct gtacctttat caacgattta tgcaaatgtt ttaggtacgg
     2641 acgcttcttc tatcatttcc cgcctgattc ctgcgacagc aatgacaaat gtcctagcta
     2701 tcattggtgc agcgttagtt gctcgtgcgg gacaatcaat gccaaaattc aacggtaatg
     2761 gtaaattaat ggaaaaaggc gaccttggcg atggaaaacc tagaaatgta aaaccttcca
     2821 ttccacaatt aggtgtcggt ttgatggtat cattgacttt cttcatctta ggacaaatct
     2881 gtaactattt tgttcctaaa gtccatgctt acgcattcat gatcattatc gttgttatct
     2941 gtaaaatcgc aaacctatta ccagaatatt acgaagatgc agctatcatg ttcaacaact
     3001 tgattgtcaa aaacttgaca gcagctgttc ttgccggtat cggtattgcg ttattgaatc
     3061 taaatgtatt ggcttctgct ttgacatggc aatttgttgt cttatgtttg acaagtgtta
     3121 tcgcgatttc agtagtttca ggatttgtcg gtcgtttgtt tggtttatat ccaatcgaat
     3181 caactattac tgctggctta tgcaacaact cgatgggtgg tacaggaaat gtagctgtct
     3241 tatctgcagc taatcggatg gaacttattg cttttgctca aatgggcaat cggcttggtg
     3301 gtgccatcgt tttgatcatc tcaggtttct tgatgcaatt actttcttag tcaaaaaaaa
     3361 tacctgatca tcaagtatcg gcttgatgac caggtatttt ttgataaaaa tttacaggat
     3421 tttcaaaaat cttttttgca ttttatcgga atgataaccg atgcgttcat aaaatcggtg
     3481 tgcttctact ctgtattctg cagaattaag tcttattgct gatattcctc gtcttttcgc
     3541 ttcttctacg ccagtcatca aggcctttcc gattcctctt ttttcagcat gtttagacac
     3601 agcaagtgcc ataatattga acatcggatc gctgaaaatc gattcatagg actccgcttg
     3661 tacatagcca gctgcttttt tagaagtagg atcttcatag accaagaaaa aatttttttc
     3721 tggctccttc aacagtttct tcatttgtct caccgtaacg gttaatggta catcatatcc
     3781 taattgttcc gcattgattt ctcgtagtgc ttctgcatct cctaaacgca tttcccgcaa
     3841 catccaaatc accagccaat ttttattttt ttaaatgaat ttttttatca cagtatactc
     3901 cttttttcac ttaaaaaaag acttttcagt gattttgact tgcttgaatc cagatccttc
     3961 taatgtttgc aagatgacga aagcattgta aagattgatc aaaagaacca cgatgacaat
     4021 cgcttgaaaa ataaaggtca ctttttttgg agacaaaacc ctgctaaatc ttgctcccca
     4081 caaacctcca ataacagcag cggggataac ataaaacaac atagataaat caaagcgcat
     4141 aaagctactt gttaaagcaa tcgttaccaa ttttgccagt tgagaaaaga aaatcgtaga
     4201 tagagaatat agtgttgctt cttttattgg caatgcaaac atcagcatca acaaagaaac
     4261 attgactggt ccaccaccaa tacctaaaaa actagctaaa aagcccagaa cccccccaca
     4321 tataaggtac caagtccatg acgtcaaatg aaattttggc tgatgatgct tggtgtagaa
     4381 gaacgcaaaa accaaggtca ataccgtcaa aaaaatttgg atcagctgca catgcttctc
     4441 gttttcaaat aactgtaaaa aaacttcgaa tacaatgttg ccgactactc ctccaacaac
     4501 agctccacta gatacccaac cgacaatctg ccaattcagt gatttcccgc ttgatacttg
     4561 tcgcacagtc gaaacaatgg acatcgtgaa taccgcaact gttgagtaaa aagaaatccc
     4621 tgcaacagaa tgggcgccga taagatcaag aatcggtttg atcaacacgc ctccacccat
     4681 cccggaaata gcgccaactg tgttcgccag aacgatcacc acaaaataaa tcagaccaat
     4741 catcttgtat ttcctttctc ttgtttatat cttttagcga ttgttactct tttcttttat
     4801 tatacagtaa aagaaacaaa cgaggcttcg aaagcttttc tactttttaa ggaaatttag
     4861 tgctaaacga aaaaaccggg ctctactttt cagagagtcc agcttttctt acaccttatc
     4921 gattcttttg ttctattctt cttccgccat gaatgtattg aatacttctt cgatcatatc
     4981 ccattctgcg tctgtttcga tttgttctaa ctcgccttct gttccatctt cgttttcgat
     5041 gtatgcataa gcttgtaatt ctacatcttc atcttctgaa acaccagctg gatataaaag
     5101 aacatagtta cgtccaaatt cttcttgtcc gtcaactgtt agcaagattt cgtataatgt
     5161 ttcatttcct tggtcatcca ccaatgtgat gtgttcgtgt ccttcgtgtt cgtgggaatg
     5221 gttatgttct gtcataagat tacctctttt ctttttatta ttaaaataat tgcttacctg
     5281 agccgtctaa ataattttgt aaaatcatca cagctgctaa tttatcgatg actttttttc
     5341 gtttcgctct tgaagtattt gcctgctcta ctagcatacg ttctgcctga acagtggtta
     5401 gtcgttcatc ttgataatca accggcaagg agaatagttc tttgatcttc tctccatatg
     5461 acatggaagc ttctgccctt ggtccgatgg aattgttcat attcttaggt aatccaacta
     5521 caaaacggtc tacttcgtac tgcgccacta attccttcaa ccgatcaaaa ccaaactctt
     5581 cttctgcctc attgattcga atgatttcta ctccttgagc tgtccagcca aagggatcgc
     5641 tcacagcaac gcctactgtc ttagaaccga catccaagcc cattactctc ataaattcac
     5701 tccatgattt gagaggtagt ctttgacaat tacttccatg atttcatcgc gttcgtgacg
     5761 gcgaatcaaa tttcgtgcat cacgataacg aggaatgtag gccgggtctc cagaaagcaa
     5821 gtagccgaca atctgattga ttggattgta gcctttttct tccaaagccc gataaacaat
     5881 cgctaatgtt tcgctcactt cttttttgcg actatcgtca aaaccaaaac gtacggtttc
     5941 atctgtaaaa cccatgattc tacacctctt tcccgcaagg taattccagc ttaccttcta
     6001 cacccttatt ttactcgaag aaagggaaaa ctacaaacaa atattccaaa cttctgaata
     6061 aattaagaaa cacgatttgt ctgatttttc cttttttctg tggctttttc aaaagccctc
     6121 tttccataaa gtatacgcta tatttctttg aaagtatgtt tttacacaat tttttcataa
     6181 agttcataaa aaattcgaat tgctgctact aatttttcgt tttcgttgct tgccctgtct
     6241 cataattgat ggtgtagcca tcttgaacat tgtagataaa gacattgaat tcaatttttt
     6301 tgtcttcaat gctttctgct tccaactgca cacctcttgc taccagttca tttccctcga
     6361 aatgaggagt gacacgatag cgtacatgat gatttgtttc cttgatatat gccgcaatat
     6421 cattttcgtg ggcaagcatg tacggagcat tcaacgaacg tgtccctgtc attaagtttt
     6481 taatgttatt attttgacca gtcaactgga aaccaatcaa atggctgcgg ttgtataacc
     6541 attgtccgtc acttaatttc ttttgtttcc aacctgtcgg atcaatatac aaaggttctc
     6601 tcttttcagt aggaaacaag tcttttccca acatcgcatt ggcttgtcct actctgttca
     6661 atttgtctat atttgaatag ctttcccatg tccctttgga aagactaaga tcctcttttg
     6721 taaactccgg ctgattccca ttgatttcta tttcttgatg ttttccatca tattctggca
     6781 catccgctac ttgagaagct tgcggtgtgg aatcaaaaat ggttgtaatt tgttggaaga
     6841 tatctgaatc tttttgtgtg gtggaaatac cgagtgcccc tgcaatcaca gcagcgacga
     6901 tccccacgat cgccttggtt gtttttttgc tcatttcttt actcctttac taacagttcc
     6961 ctaaatctta acatatgttc ccctataaat aaatactgga aagaaataga aacagtaaaa
     7021 aaataaaacc agtttttaga cggcttaaga atacaaaaaa agagacggat tcatcgtctc
     7081 tactcaatca caaaacacta tttacaaggt atttattatc attcaaaaaa tttttcttaa
     7141 tactcaaaac taaacggctt ctgtacgacc tcttggtaaa cagtgttcaa aagcttgcat
     7201 ctgcggtaat aagtccaacc aagtcaaaaa cataagaagc ttttttgctt gactattctt
     7261 attacttgat gcagggcagc tttttcacag cctcttttaa gcgggtgacg ggaatcgaac
     7321 ccgcgacatc agcttgggaa gctgggattt taccactaaa ctacacccgc gatacaaaaa
     7381 cagtatacgc ctctttcact ccttcctcaa gtttttttat tctttacgct tccgatatgt
     7441 tttgtagtaa aataaaacta atcaatcaat tattggagaa gatgctatga cgggaaaaga
     7501 attagatctg ttgctggaca cttgtttact cgctgggaaa atcatgatgg aaagcaatgc
     7561 ggagatgtat cgggtagaag atacgatgag tcgaattgct ttagcttctg gaaatttccg
     7621 tttggtcagc tatgtcactc aaaccggtct ctttattggt cttgatcgta cctcgaccat
     7681 ccgaatggaa caaattacca accgttcgat taatttagaa aaagtagtaa aagtaaatga
     7741 tctttcacgt aaatatgttg cttcagagct aacattagaa gaactttact gcgaactgca
     7801 agcaatcgac cgagaccgtt ctttctttcc tgtctggttg caaatcgtta gcgcggcagt
     7861 gatcagtgga acaattatgg tgttatttgg cggaaagatg accgatttac ctgtgacttt
     7921 agtcattgga ggattgggat acgcagctta tctatatagt ttgaaatttt ttagaatcaa
     7981 atttttatcg gaatttttat cttctttatt gattggcata gccgctatct acagcgtacg
     8041 ttttggctta ggaagcaatc aggatctaat cattatcgga tgtgtgatgc ctttagttcc
     8101 tggagttcaa attacgaacg ctatccgtga tttgctagct ggacattatg tctcaggagt
     8161 ttctcgcgga acagaagcga tgatgactgc tacgatgatc ggttttgcga ttgcttttat
     8221 tttccagctt ttttattagg aaaggaacac aagtatgggg acgatattta ttcagttttc
     8281 ttttagtttt ttagcgactg cggcatttgc cgttattaca aatgtaccta ggcgttcatt
     8341 gatttgttgt ggtctttctg gtgcttttgg ctggatgatc tactggatct gtgttcaaat
     8401 aggcggatct gctgcttttg gttcattgct tggttcttta ggagtagcat tcatcagcga
     8461 tcttttctct aaacgtttga aaatgcccgt aacgattttc aatattcccg ggatggttcc
     8521 tctagtccct ggtggtttag cttatcaagc ggttcgaaat ctcgttactg aatcctatcg
     8581 agaagcggct cattatgcgg tccaagcaat tatgattgct ggagcaatcg ctttaggtct
     8641 tgtattatca gaagtcttta accataacat ccgtaatttc aaagtaaagc gtgacgcaat
     8701 catgatgaaa cgaaaaaaac ggctttttaa ataaacgaag tgtaacaaag aaaaggttgt
     8761 gaaagagacg ttcagccttg agcgatgaca aaatatctca caaacattgc gacaagtaac
     8821 cgcaggagca ataagaagta attatgagta ttaaaaaaag ttttgtaaaa atagcttctc
     8881 acatttttac ataaaattga cttaatactg agaaactgac ttttgaacac cctctatctg
     8941 taaaaaaggg gctgcgacat gatttttgtc acggcccctc ttctttattc aaattttttc
     9001 caaaacgttc gttgataata aacgatccat agagcggaaa gtattagaac taaaccgatc
     9061 acaggaatat tcactaacca aaatggataa aacaaagcca acattccgta taagacgata
     9121 agaataatac tgatgatcaa tgaacccatc atagttgcga ctaaacccaa acttcctgaa
     9181 cctctgttaa ataattggtt aatattggtc cagttcagca gcagcaaccg ataatctcta
     9241 gcgaaataac gtagtgacaa taagtagcag ccgaataaag aaccaaatag caagctaggg
     9301 ataaaaaaca aaggcagctg aaaagacagt ccgcttaata atgcgatccc accagttaaa
     9361 aaactctgca atatccatcc gaatctgaac ttttctttta aatattggtt catagagatt
     9421 ggcaaagaac ggataaacag aaaattttct tgatccaaag aaataagatt gctgataaaa
     9481 gaagtctgat taactgttaa gaaagccaat gcgatcccta ccaggaaaac aacaccgatt
     9541 aacttattat ctaaatcagt taattttatt tcgcctccta gggcaaaagc aagaataaaa
     9601 atgattggag ttaacaagga agaagaaaga acttgcataa tcaaattagg ttcttttact
     9661 aattgagcat tgtaactaaa taaaagctga tgcacatttt ggttcttttt atgggttctt
     9721 tttattttga actcactgtt tgaatcagtc agttgctctg taagctttgg tactatcagc
     9781 tgttttacag caaggaaaaa tcccagagcc gtgatagcta gtattcccca acccaataaa
     9841 ccttgttgag aaagtggctg actggcagca tcatagaatg gcaataatat cgaaatcgga
     9901 tgccgatctg ttaactcatt ttcaatagtc cccgtttgat gattcatcca catgattcca
     9961 gcaaatgcga tcagcatcga gctgccaagc aagatactag aaactgtttt tctatgtttt
    10021 ttaaacactg ctgttcgagc caaaccaaaa acaatcaaac tagccagaca aaaaagaata
    10081 atcaaaaata gagaaaacaa aaggattgag ataatgatag taagcaaaat ccctagatca
    10141 gctcgccatc cggttaaaat aaacatgact agaagcggaa aaacaaaagg aatgatggtc
    10201 aaagcaacta ccaaaatctt tgctgaaaaa acctgttctt gtccaaaagg cagaggcaaa
    10261 aatacttgca ggtcatttcc ttcaaaaaag atattataaa tgactgatat actttgagtt
    10321 aaacctaaca taccaaaaag tgccacgtaa taagtaaaga aacctggcaa tttaacaaag
    10381 ttcatagcaa acatagcaaa tccgtaaatc agtaaaaaaa tcagccctga aaaaagattt
    10441 tgagacaaaa gatagatagt taatcgcttt cccttttttc ctttctctct tgctttattc
    10501 gtgagctgtg gattaacata taaaagatta actcgaatta attctaataa ttgtcgctta
    10561 tacatacggt ccatctcctg tcgcttgcct tccagccatt ttcaaataaa tcttttctag
    10621 cgtttcatca ggtgagccat tcaataattc actaactgcc ccctgataaa tcaattcacc
    10681 tttcttcaaa atagccagtt tatcgcataa ctgttgtgcg gtatccaata catgtgtaga
    10741 aaaaatgact gtttttcctt ttgcggcatg agccttcatc atttctttca aatcaaatgc
    10801 tgcttgagga tcaagtcctt gcaaaggttc atccaatacc caaatatctg gatctggcag
    10861 caacgtgccg atcaaaatcg ttttttgacg cattccatgt gaaaaacttg cgattgtttc
    10921 attttgatga ctatacatat caaaaagcgc tgtcaattct gctaaacgct tttctttttt
    10981 ttgtgtgtct aattcatagg cagctgaaat caagtcccaa tattctccag ccgtcaattg
    11041 taaaaaaata tctggggaat caggcacata accgattttt tgtttgatac tcaatcgatt
    11101 ttccgtcaat ttcattccat ctactaaaat cgttcccgat gatggttcaa taatactaac
    11161 taaactttta atcgtagttg attttccggc accattatgt cctaaaaatc caaaaatttc
    11221 cccttgtctt atcgagagag acaagtcttt taatgcttgt tttttcccgt aacttttact
    11281 tacattgatg aattcaatca tttctgtact ccttttgttt gttattactt tttattgtac
    11341 ccttcgttat tggtggagta aatgtcaaaa agagtgcata acaaaaaagg atagaaacga
    11401 ctaggctgct acttgggttg ttctcttcta caggaaaaca ctcttctaac aggtaagata
    11461 tgagtctttg ttttctttaa aatgattcat tttctatctt ttcttgcata aaattcttta
    11521 gtttatcaat acttctcttt cccatctcta gttgttctcc atttgcaaat gttactattt
    11581 cgtttactct gctaatagat gtaatgtttt cagtattaat gatataagct tttaaatctt
    11641 tacataaata ctcatattcg agtgattttt tatatttttt aattgtgccg tttacgagaa
    11701 tctcttcatc tttcaatact aggcctattt tatttttata acctggcatg ctcattagat
    11761 aaaggatttc atcgtaatgg atatagtgat cgctattacc ataacggaca gttgtccacc
    11821 tttttttcgt agcatgttga acaggatagt tttctttttc tttcaataag taactttgga
    11881 tgcttttttt atttttttca taagtgaatt cttttatcaa ataaccacta ggcgtaatct
    11941 ttcgattaat aacagttatt gctttattcg gatgagacgt tagataaaca attttacact
    12001 tttcattctt ttctctaagc atttcgccta gttcgatacc gctataatag gcgttcaaat
    12061 cgatgtctag gaaaaaaata tctgaggaat agatttcatt atttttaatg aattcaacaa
    12121 attgtataac gttcaatccc tgaacgatct caaatttcca aggacttaat aaaattctgg
    12181 attcttccaa aatttctact agcatttttt caaaaaccaa actatcatcc aaaataaata
    12241 tacgcgttac cataaaaagt acctccactc gatattttac tatcaaaatc atttcataca
    12301 acttttcaac atacatgtta ggaataaatt gtaattctct tcacaatctt ttccaacacc
    12361 tttgaaaccg atatcaaata ctttcaggat gctgcttcta aaataaatat caaacaaatg
    12421 aatacatcat gcaaaaaaag ccagacaacc gacgtccttg cgtgtcagct gtctgagcta
    12481 tgtttattta ttttgttctt ttaaaaagaa cgatacacat actgattttt cggagcagag
    12541 actttctcag cgtttgtaac aactacagat gggatttcac gcttgaatgg ttgataatag
    12601 tctgattgga tggttccttc tattttatac cattcatcat ttttaaccgt tactccttcc
    12661 ggcatatgcg tcaacaaacc aaagactcct gaatctgcca cacaatggat aatgccgaat
    12721 cggaacaaga agatatctgt attgctatcg ttcggtgttt ggtaaacaaa tccttcatag
    12781 ctgatttttt tgccaatgaa ttcgctaggg taattataaa ttagctccat aacttctaaa
    12841 tagttttcat ctgtgatctt gatagtttgc ttatccccat acttttcttt caactcattc
    12901 atttggtcta agtagtctga tttgttgaaa taaatactgg tatccggctt taagtattgt
    12961 gtctgcatct ccggatcccc tactgattct ttacttactg ggaaattaaa tcctttggct
    13021 tctacgatcg tagtgtcgag actaactgtt ggaaacaacg tccccacgat tactggcaaa
    13081 gctagcagta cataagcgat tccacgttga taaggttttg acaacccatg gtcatgatcg
    13141 tgctcgtgtg ccttttcttc tgcttttccg tttttgaccc acaaatacag ctgaactaaa
    13201 gccaaaagag cagataaaat cattgaaaga atagctaagt agcgataatg gacattgata
    13261 tattgatcga gtttgccaga aacttgcaag tacatcatca attcgaaata cccagataaa
    13321 atcaaaaacc gcagcatatt ttccctccta aataaataat gtgaatccaa taacgctaag
    13381 ggcaatcagt ccgatcagcg ataaaataaa gcgtcctgta aaatatcgtt tcatcatcag
    13441 tagatttttg atatcgacca ttgggccaaa gaccaaaaag gcagctacag gtgctgtgcc
    13501 gaacagactt aacaaagaag atcctataaa cgcatctgct tctgagcaaa gagacatcgt
    13561 aaaggccaat aacagcatga tgataatggc taaaatcttt gttgagccga gcgttagcat
    13621 aattctagtt ggtaaataag tctgcatcgc agctgcgatt aatccgccaa tgatcaaata
    13681 acgacctgta tcaaaaaatt cgtcgattga atgtgtcaac acatgcccag tttgatggat
    13741 cagctgattt tttggttcat tcttctcact ttgttcttct tcatggacat gatgatggtg
    13801 attttctgct actttagacg tgattttttc tttcaataca gcgtcttttt gaaaataggc
    13861 aagccagaca ccaatcacaa gggcaacaaa aaagctgcct atcacccgcc agcttgccat
    13921 ctgccaagaa ttgccaaatg cgataaaagt ggaaaaaatc acgattggat tgatgatcgg
    13981 agcagtcagc ataaaagcaa acgctgtgtg aactggtacg ccttttttaa caaattgatg
    14041 aacgatcggt acgatgccgc attcacatga aggaaagaaa aatcctaaga tcgaaccagt
    14101 aaaaatagag aagatacgat tttcaggaag ccatctcttc acacgttctg gggtcaaaaa
    14161 tacttgtaag gcgcctgaga taagacagcc taataatacg aaaggtaatg cttcaataac
    14221 gatcgataag aaaatcgtac tcatctgcaa aaccgaattt ggaataaaag aaaacatgag
    14281 tttcctcctt tttatttcta gttcattcgc tttgcaaata tacgctttta ttcaaaaaaa
    14341 acaagttgct ctgtaaattt ttacacaact cttatttttt accaaagcac ttcaattgac
    14401 tttttctgtt attcccatta aattaaggtc tcatacatat cacttctatc ataaaaggga
    14461 gaataaaaat gaaacaaacc actaacttga ctgaagttca agacatactg caacagtcat
    14521 ccgttgccgt catttatctt tcgatgccta attgcagtgt ttgtcacgct gttcgtccac
    14581 gactagagga acttctcaca cattatgata ttccggcact tcatttggat gcatttgaaa
    14641 caccagaagt agctagtaaa tttgaagtgc tgactgcgcc agttgtcctg atttttcatc
    14701 aaggaaaaga agtctttcgg caagcacggt tcatcgactt taaaaaaatc cgttatctac
    14761 tagatgaact gacagcagaa gatgattccc tttcttatga agaaatcttc cgaacaaaat
    14821 aatcgttgtc caaacagaaa aaagcgattg aacaagtgaa agttttgcct tcatttgttc
    14881 aatcgctttt tatttttatt ctgctgtatt ttcggaatgc gcatttgcgt cagaatgcaa
    14941 gaaatagatc aaggtttgca attcattcgt caaatcaaca ttttggatca atacatctga
    15001 cggagcattc aatcgagcag cggtaaagtt caagattcct ttgattcctg cttccgttaa
    15061 ctgattgact acttcttgtg ctctttcagc gggtatcgtt aaaattgcta cttcgatttg
    15121 ttggatcttg atttgttctg acatatcttc cattggataa acggggatac cgtctacgat
    15181 gcgcccaacg atttcctcat tcacatcaaa agcacaactg atacgtatgc tattactttg
    15241 atggaatttg tattttagta aagcacttcc caagttccct acaccgatca gcgcaacatt
    15301 tgtcaattga tcgtcgttta atgtctttgc aaaaaagtgc ataagatctt ctacatcata
    15361 accataccca cgttttccta attcgccaaa ataagaaaaa tctcgacgga tcgttgcact
    15421 atctacttga acggcttcac ttaattcagt tgaagacact tttttctttc cagcattatt
    15481 taaaatcctt aaatagcgat aatacaaagg cagtctttta gctgtcgcct ttggaataat
    15541 atgatctttc acgaaatgac ctccacgtat tgtctaatta catctttgat ttctccatca
    15601 tagcagtatt tataggaaaa aatcaattcc attgctcaga tattgtgaaa ttttattctt
    15661 tattcattta tttatcattt ctgcaaatct cgcagtataa tggaatttat ggtagactac
    15721 taattgaaaa atagtttttt atttgaggag aattcacaaa gtagaaaaga ggattccatg
    15781 atattattac aagccaatca gattgctcgc cattttggtg cagaagtctt atttgaaaac
    15841 atacatttag aaatcagtac aggcgctcgt gtcgctttag ttggcagaaa tggcgctgga
    15901 aaatcgactt tattaaagat cattgctgga attgaagcac ctgatgaagg aaagatcgct
    15961 aaaaataaaa cagcgactct cggatacctc gctcaggaca caggacttga ttccaatgaa
    16021 acagtttgga acgagatgct gaaagctttt gaacaagtta gacaaatgga agagcggatg
    16081 cgcgagctag agattttcat tagcgaaggt acgccagaca cacctgctta tagttcttat
    16141 ttaaaagaat acgaccggct gcaacacgat ttttcagatc gaaacggcta tggttatgaa
    16201 aatgaaattc gttccgtatt gcatgggttt aaattcgatt cttcatttta tgatcagaaa
    16261 atcgatactt tatcaggcgg acagcgcaca cgtttagctt tagctcgcat gcttttgcaa
    16321 caccctgaca ttttgattct agacgaacca acgaaccatt tagatatcga gacactttcc
    16381 tggcttgaga attatctgca aagctatact ggtgcattat tgattgtttc ccatgaccgt
    16441 tattttttag ataaagtagt caatgaagtc tatgaattaa gcagaagaaa aatgcgccat
    16501 tacaaaggta actattcgaa atatctagat ttgaaagcag aacagttagc aagtgaatgg
    16561 aaggcttatg aaaagcagca aacagaaatc cataaattag aagacttcgt tgctcggaac
    16621 cttgttcgcg cctctaccac aaaacgagcg caaagccgca gaaagacatt agaaaaaatg
    16681 gaccggctgg atcgtcctca aggggatgaa aaacaagcaa actttctatt cagtatagaa
    16741 aagccttctg gaaatgtagt cttgcaaatc gaagatgccg ctatcggata tgataatgtc
    16801 accttatctg aaccaatcaa tctagatatc cgtcgtcaag aagcgattgc tctagtaggt
    16861 ccgaatggta tcgggaaatc gacgttgctg aaatcaatca ttcaccagat cccttttatc
    16921 cgtggaaaag aaacgctagg gacaaatgtc accatcggct attacgatca aggtcaagct
    16981 gatctgcata caaacaagac gatcctagca gaattgtggg atgagcatcc taccactcca
    17041 gaaaaagaga tccgaagtgc tttaggtgct ttcttatttt ctggcgaaga tgtagaaaaa
    17101 ccaatccctc tgctaagtgg cggtgaaaaa gcacgggttg ctttagccaa gttagcgatg
    17161 aacaaagaaa attttttgat tttggatgaa ccaacaaacc atttagatat tgacaacaaa
    17221 gaagtattag aaaatgcatt gatcgattat gacggcacac tgctttttgt ttcccatgac
    17281 cgatatttca tcaatcggat cgcgacaaaa gtcgtcgaac tctctgaaaa tggcagcaaa
    17341 gtctatctag gagactatga ttattattta gagaaaaagc aggaagaaga agaaatcgcc
    17401 gaattgttgg cacaagatga gccagaatct gctcctgctc ccacgaacaa atctgattat
    17461 taccaaagca aagaacagca aaagcttatc cgtagccttc aacgaaaaat tactcaggtt
    17521 gaagaagaaa tggcgcggat cgatgaatgg atcgatcagt tggaacaaga aatggtcgcg
    17581 ccagaaaacc tggaagatca cgtaaaactc aatgagctga accaagattt agaagctgct
    17641 agacaagatc aagaaacaaa attgacggaa tgggaagaac taagcttgga attagaagaa
    17701 tatgaaaatt aacgaaaaaa ccaaaacaga aaccattcat gctgttttgg tttttctttt
    17761 tttattttat caaacaaaaa ttccatattt acctttttca ccaataagaa gaccaattac
    17821 tagtcattct cactaaagct tctaaataat agtaatcacc ccaaatacaa ggtgtattta
    17881 ccccattatt tttgggctta ttataaacag actgtgttaa aaagccatct tcttcttccg
    17941 ttgtagcata tctttctttc aattgtcgca taattttcca aacagcagac tggtataagt
    18001 tcttttctgt tttgtctaat agacctgatt ctattaattc taataatcca caaaccatga
    18061 tcaccatact agatgtatct ttttcttctc tgctagaatc atcaaagatc aaatcccaat
    18121 aacaaatggt atcttctggc aaccgattca taaaataatt ggctaatatt ttgcttaaat
    18181 caaaatattt ttgttctttc aaataacgat aacttaatgc aaaaccgtaa atcccccatg
    18241 cttggcctct agcccaacag gaattatcac tataaccttg atgcgtactt ccatatcttg
    18301 gttttccatc tttgacatcc atataaaatg tatgataagt tgaaccatct tctcttacta
    18361 aataatctgc tgcattttga atatgagcct gagcagcttt tttatatttt tgatttccag
    18421 tttcttcact cgcccaatac aataatggaa gattcatgca acaatccatg atcattctac
    18481 cttgttgtga aggatcacta ggatctcccc aagcttgtat aactcctgcc ttctcccaaa
    18541 aacgctgaag taatgtttct gcagcatcaa ttgaagcttc cttcattttt cgatttcccg
    18601 ttattttata atctgctacg gttgataaag aatacaaaaa accaagatcg tgatgattag
    18661 tgataatttg acagtcaatc ctgtggataa aatctatatc tgctttttca gctgtttgtt
    18721 gaaataaagg atcacccgtc ttctcaaata acaaccaatt aattcctgtc caaaatcctt
    18781 ctgtccaacc aatattgtct cttaatggat aacgtccttt tataggacac tcgcttggga
    18841 attgatactg actgttactg atacgtttga ttaacctctc cgtgtgtctg cgacaacgct
    18901 cgatctcatt attccattct ttttccatta attctttata acattcattt atccattttt
    18961 ctggatgtat tatctcttca aacatcactt tatcaagcat ttccccacca gcctttagca
    19021 taattttagt ctttttttat tgtttttatt ttggatagtt agcccggttg tcccatcaaa
    19081 atcaattttg ggacgattgt tccatacttc taaactataa tcccgatctt gatgagcaac
    19141 cactcctgtt ccgagccaat gggttccttt tccaaatgta ccctctaatc caggaataaa
    19201 agtgttttcc catgtcatca agtttgtatt gggcaaaccc ataatagctg tggattttcg
    19261 tttaatagta tcgtcactta aacagataat acctgaaaag ccagcttcac tcaccctata
    19321 gttttccttg tcttcttcta tgattattcc ttctttctca ggagaacatt caatagcaaa
    19381 ccctgtctca tatagaacat attctgtatc taattctact ttgtgtacgc gaatctgcca
    19441 gccttcaaaa ggaataagcc aagttctgat ttttgcctgt aaagtaggtt cccatgtaga
    19501 ggcaagtacc tctttcttac atacaatgtc tcgtacatta tttcgaacga tgaactgtcc
    19561 ataggttttg atgctctcat tcttaaaact ggtcgtgata tatgtgtccg ctcgctgaat
    19621 ccctagcatt gaatccattg ccatttctgc tttcaattga ttcgctcgcg gtatcgaaaa
    19681 accaaattga ctagaataag caaattttaa atatttttca ttggtcaatg tatggaaatt
    19741 tggccctaat tgtcccgcat tcaaaaaaaa tgtatgtcca ttatcatgtt gtatgagcaa
    19801 attggcttct gaaagaagtt tagttccttc acgaataggc ataggcattt ctttagccgt
    19861 ccaatactca tggtcttcag gtagcgccaa caataaaaaa atcttattca gccataatgg
    19921 agataacgta ctattatagg gttcagtcaa tgtcaattga gggtaggtat aaccaatatt
    19981 caggatacct ttttcatcaa atatttcttt ttgcatccac catcttatat tccgattgac
    20041 taaccccttg atttcaccta atttaaaagg caaaagatcg gcccacaaca tagctgacca
    20101 aaagcttgaa actgcaaaac gataaatcat gcttcgacca aaaggcacat ttgcaccatc
    20161 ttccgcaaaa aaatgaatat agtctctaga aaaatcaata gctcggttct tatatatctg
    20221 gctaatgggc ttttctggtt ctagtacgct ataaatcaaa ccataataat gaaatgcaaa
    20281 aggattataa taatcttggc gacctcttga actgtctcga taccagccat tttgaagata
    20341 acaattttct atattatcaa atgcttcttt cagtgctgat tctttaactg gataaccaaa
    20401 tttttggata attgttccga caattatctt aaaaaattgc caattaccat ctgcacattc
    20461 atattcaaaa atttgcgaga accaatgaat aatctggctt ttttctcctg tatctaattt
    20521 tttccataat aattgttcat gatgatataa cgctaataac attgcgggca tttctaccat
    20581 acgctggtct ctttcatgta tttctcccca ataatcggga tgggaaggat ctgttccagc
    20641 ttttattcct gatagaatta atttcaacca tcgttcatct aattggtcaa ttgcgggccc
    20701 cgctccccat aaaacccgag agaatccttc cattcctgca attttatttc catatcctac
    20761 cccttgatgt atataatcaa tttgtgcgcc acttgctcga taaaacggct ggagtggttg
    20821 atttatcttt ttaaataagt caaagtaatc ctgtctggtc cttaatagtg gtactggatg
    20881 tttcattgta ttttctcctc tttttactac caaatagcta attccgactg ttctaatcga
    20941 agtaagcctt caataaaaaa ataatcagaa tagatcagtg gcacattata agtcagttct
    21001 ctatggtatg cttctgctcc gcctccaatg atcccatctt catccatatt ccaatttgca
    21061 tagtgctttt ctgtcttttg gagtatattg atagcagctt catgatacat ttttgatcgc
    21121 acagaggaaa catatcctgc taattccaga agaccgcatg cagcgcatac tccagcactg
    21181 gtatcaatat tcgaatcttt tacagcaaaa tcaatgagag gaatataacc agttttttcg
    21241 attttctgaa taaaatttac tgctatcttt tctgctatag ctagatagta cggatttttt
    21301 gtgtaacgat aacttaacgc gaatccatat aaagcccatg catttcctct gctccaacaa
    21361 gaattctcat tgtatccttg cccgccaagt aaccgaatat atttccctga ttctgcatca
    21421 aattctgcga tatgcccggt tgatccatct ttcctcacta gatacttagc tgttgtatct
    21481 gcatgctgcc gagcaatttt agagaacctc ggatcaccag tttccctcga agcccaatac
    21541 agtaatggta aattcatcat actatcaata atcatccaac caggtttatg gtcattccat
    21601 gctactaaat agttccctga aatattatag cgtccagcaa gtaccgtagc tgcatgtaac
    21661 cctagttgtc gactatgttt gttttgagac tgttgataat gtgcaatagc cgatggtaag
    21721 aataaaaaac ctacatcatg atgaacgtct gaaaaatggt acagggcaga ttctaataat
    21781 tgttcttgtt gtattgctgc ctctttgaac ttttctcgtt ttgtcttgtg aaagagctgc
    21841 cataaaatac cactccaaaa accattggtc caccagtcga ttcctctgtc ctttattacg
    21901 tctgtatatt ttccgttgta agaaatatat ggaattttat tccccattct gtctaattcc
    21961 gcatctatct tttcagaagc tacattcaaa atttttcttg accattcctt cgtctgttca
    22021 ttcatggata tcccgccatt cttttaattt ttatgaatgt ggagttgctc ctagaacgaa
    22081 ctagatggtt aacattcgtt atttttttta cttatttgca gctccaatgt cattctcctt
    22141 aaatttagac tgcgcccaca cataaatcaa gaccattggg atcactgaag ttgctaaaat
    22201 tagcataatt gcgccataat taattggctc acctgtacta gaaaccgtca tatttttgat
    22261 aattaaggga accgtatatt tatctttatc tgaaagcatg actaatggaa atagatattg
    22321 attccaactt cccataaaga taagtaaacc actagtaata atcgtaggtg ataaaatcgg
    22381 tacagcgatt ttcgtaaaaa tcacccactc attggcacca tcgattctgg cagcctccat
    22441 cagtgctgta ggaaattgac tgctatattg tcgcatcata aacactgaag ttgtactggc
    22501 aatcgaaggg atgatcacac ctgcataagt attcgataat cctaaacgac tcataatgta
    22561 aaataaagga atcaatgtgg taaaaaaagg caccatccta gatagcataa ctgtattgaa
    22621 caacagttta ttccccataa aacgatactt tgctaatgca taacccgcca ttgtagaact
    22681 ggctgtagct gaaactgtac tgattacagc aataacaatc gaattccaaa taatcaaggg
    22741 ataattatat ctcgccatga tggcttgcca gttttttaat agcatatccc caaacttgaa
    22801 attgattccg ccacttaaaa tttcttgatt actttgcgtt gaagctacaa tcatatataa
    22861 atatggcatc aaaaatatta aggcaccaaa cacaataatg acgtacgtaa aaattctgct
    22921 ttgtatcttt tgtttagtca tttttatcac ctccgaattt aaattgaata gccgataata
    22981 taacagatac aaacaccatc gtccaggcaa tagcagaggc ttttccaaaa tcaaccattt
    23041 caaaacttgt tttatataaa ttgactccta cgaccaaagc tgaattttct ggtccattgg
    23101 aagtcccaaa gaatatattt gggatattga aattacccaa gccattgata gtggctaaaa
    23161 ctgtggccat taaaatgatt ggctttagca tggggatcgt taataaaaag aattgccgaa
    23221 atttcgatgc tccatctatt tcagcacttt cgtatatctc tttagaaatc ccttgaagac
    23281 cagctaaaaa taaaatagtg ttatatccta cactaagcca aatcatcgtg atgatcattg
    23341 atattcgtat ccaaaaagga tttgttaacc actgtacacc gttaattcct agcgcattca
    23401 aaaatccatt gaataaccca gtcggattga aaaaagtcat gaatacggaa gctacagcca
    23461 ccgttgatgt aatggttgga atataataga cagttctaaa aaatcctttt ccttttaact
    23521 gtgctgaatt caataaaaca gcaaagtaaa tagctaatag catcgttatt ggaattgatc
    23581 ctgccatgat aatcaaaaca ttcgtgtaag atttaataaa caatggatct cggaagatag
    23641 ctagataatt gtcaaatcca acaaattcaa atgagtagcc aattttcata aaactaaaag
    23701 caaacgagat aatgatggga atcaaaatcg tcacaataaa gaaaataaca aaaggtgtga
    23761 ccaatccata agcacttttt ttatgagacg tatctgttgc ttttttcttg ctgttcttta
    23821 ttgtcttgct tggtaacgaa gattgcatca tcgttaagtc ctcctaatat tttttaatca
    23881 ccagttaatt ttacgccgta cttatgagca aaattttctg cttcttttag atatgaattt
    23941 tcaaaatcac ctgtttgcca atagttatat gcagcggtag tcaaataaga cgtagcatct
    24001 gaataagtgg ctggtaaaac agtatttgat gtattttcat tgattttatt caatagttca
    24061 tagtattttt gtcctcctta gtagtcaaac tttttctcag ctgcttctgt ttgataggcc
    24121 aatgagttag atgtagccac gcccagctcc agtgcgttgg ctaagcattc ttcatctgtc
    24181 agcataaatg taagaaattg ttgtgccact tgtggatttt tggcatcttt agggacataa
    24241 aaacttgatc ctcctgatac tgcacctttt cctggatttt cttttgaaaa aggaatcagt
    24301 ggagccatgc gccatttgtc agatgcatca ggaaaattca aagacatatt cgtagcatac
    24361 cagccgccag caacaaacat tgcagattct tgaaatgctt tctcagcatc ttgtgcaccg
    24421 tagaaatgta caatatctga gtcgatcatt tctttgatta actttgcagc atgtttcgct
    24481 tctttagtat tcagacggat atttccttct tcatcaagca aagattgatt ctgctgggct
    24541 agcatgttga taaacaattc ttggtcccca gattctggca aggcaattcc aaaactacca
    24601 gttttttctt ttaatgcttt tgccacctgg atatattctt cccaagaact gatttcttca
    24661 aaatctacac ctatttcagc aaattttttt ggttgataat aacaaagtgc tggggtaaaa
    24721 tcactagccc aaggaataat cgtttcatta ctcgtttgtt gacgcaaaat attcaatttt
    24781 tgatcataaa actgatcgcc atatttgtca taaaatccat attcatcagc actataaaaa
    24841 gcatcttgaa atttttccag cacacctgct gctgaagtgt ctgccatgga gataatatcc
    24901 ggcatatctt cgtgtgttac caattttggg gtgatcattt gtactgttgc tgttcccgaa
    24961 gctacattca caatttttaa gtcaatattt gctccagttt tgcggttata gatttttgca
    25021 gcattttcaa catagtttgt cagtttgccg tttgcgacat atacttctaa tgtagtggct
    25081 ttttttatca ttggatctgc gatgtttgct gttacttctt cgttagtttt tccacatgca
    25141 cttaagctga ataatagggt aatgtttagc aaagctatca ccaatttgta tctttttttc
    25201 atgtctatcc cttctttctt ttcaagttct tatataaaac gctttcactt atgtatatta
    25261 acggaattag taacacaaat atttatataa aaaaatattt tacttgtcgt tttggctttt
    25321 catttttgtt ataatagtca ttaattataa atagaaagct ttttatataa aaagagaaag
    25381 gaaagtggtt cttttgttaa caaacaacca atcctccaat cttgtcaaaa aaacactaac
    25441 ctattccata gatacccatc ttcatttatc tgctgctccc tattttcgac tactaataaa
    25501 tgaaagcgct aatttatatg ctgaatttgc acataaatct atagaactag ataatccttc
    25561 ccttttattc attgataaac agcaagaagt ccaaatcttt tctactcaaa aggaaacaca
    25621 aacttttatc attatccagt tttattttga tgagcaatta ttagcacata ttacgggaca
    25681 atctttttct atagatcaag aaataacatc tatcattact tttctgaaaa atgaacagtt
    25741 caaaattgat tatctaaaac atagtaagcc agctatttcc tatgatcagg aaatcaattc
    25801 ttttttcata ctatgccaac agatgagcat tcatttgctt tccttattag ttacttattg
    25861 tctgcaaaaa attcaattgt cttccttacc aaggcattat caacaggaac ttgctttatt
    25921 gacaatacct tcaaatgaga aagtcattcc taaaaaaaag catattcttt attcagatga
    25981 attagttgat ccaatcatac gatatttaga agaacatctt tcagaaaatt ttttgcttga
    26041 acaattagcc caaatttttt ttatcagtcc agccagctta aaaaaacatt ttagaaaagt
    26101 gaatggaaaa agtgttatta gctattttaa agaactaaaa atggaaaaag caaaacgtct
    26161 cgtgctagaa aatgaattaa cctatacaga aattgcagat atattaggat ttcattcgat
    26221 ccatcatttt tcttcagctt ttaaaaaata tacagggtta tccccttcaa agtattatct
    26281 atccttaaaa tagaaaaaaa tttttaggtt ttatccacaa attatttctc tatattttct
    26341 gtctattcaa aataaacaat aattttccgg cacaattatt tgctgttttt taccataaca
    26401 tagtacgatc aacgtagaaa aggagatgtt tttatgaaag ttgttgtcat tggcggtgta
    26461 gctggcggtc cttcatttgc cactcgtttc cgtcgattga atgaagcgca cgaaatcatt
    26521 atctatgaac gcggagaaaa tatttcttat gcaagttgtg ctttgcctta ttatttagga
    26581 ggtgtgatca ctgaccgtga ctcgctgatc gaacgtacac cagaaatatt gaaaacaaaa
    26641 aacaacatcg atgtctttac taaacacgaa gtaacagcaa tcgatccttc tactaagcga
    26701 ttaacagtta aagacctatc cacaaatgaa gaaataaaaa cagattacga taagttgatc
    26761 atctcttctg gtgctagacc agattatccg gatattcccg gagtttttga agcagaaaac
    26821 ggctttgtcc tccgtagtgt gacggatgcg gatcgaatca aatcgttcct tgaagaaaaa
    26881 aatccacaac atgtcgtcat tcttggtgca ggtgttatgg gtctggaatt agctgagaat
    26941 ttcaagcatc gcggcttaga cgtgacttta atcgatcaat tgccacaagt cgctttccct
    27001 tatgatccag aaattgctaa tttagtttat gacaaattgc tgaaagaagg attagccgtt
    27061 catttagaaa caagagttac tgagatccgt gataaaggtc gagaaatagt attatcagat
    27121 ggctccgtcc tttctgctga tatgctaatt tttgctgttg gtgtttctcc gaagaatgaa
    27181 gtggtgaaag caaccggcat acaattatca gatacaggtc agatcattgt tgatgaccag
    27241 ttacaaacca atctgccgga catctatgcg attggcgata ttatcgaaac gactagtgta
    27301 gtgactggtc agccgatcca aagtatgctt tccagtgcgg ccaatcgtca aggacatatg
    27361 ctggcagata ttttaaatgg tacgcctatg cgctatcgcg gatatattgg tgcaggtgtc
    27421 gcaaaaatct ttgatcatac agcaagttat gcgggaatga cagaacatga attaaaagca
    27481 tcaggcataa caaattataa aactgttttt atcactccct ttgaccatgc ctatttctat
    27541 ccagaagcta caagattaaa tctaaagctg atttttgatg cagatagcgg tcgtatttta
    27601 ggtggacaag catttggaga aaaaggtgtc gataaacgga tgggagaact ttctgtagca
    27661 atcaccggaa acttgacagt ctttgatttg cctgatttgg agttgcctta ctctccaccg
    27721 tattctacta cccgtgaccc gttgaatata gctggttatg tcgcaatcaa tcaaatgacg
    27781 aatatcgtag aaacgatcaa agcaagtgat atacccgaaa acgatttgaa agaagcgttc
    27841 tttttagata tacgtgaacc taataaagca ccttctggca gtatctcggc aacaaaaaat
    27901 attccaatga atgagttacg agatcgaatc aatgaaatcc caaaagataa aaaagtttac
    27961 attactttca gaagaggatt gaataattat acttctgccc gaatcttggc aggtttgggt
    28021 atcaaagcga ttttgattga agaataaaaa aacgaccgcg gtgggtagcc gcggtctagg
    28081 agttattttt acttgaggag taaaaatgaa aaagtatata gggttgttgg ttggtatgta
    28141 tatagaatag aagataaatg tgaagaaatt gtgcattatt tcttcacatt tattaggtta
    28201 tagtttaaga aagtttaaac attgcgcaat ttaattattt tagctgtttc ttttcataaa
    28261 aaaacatgtt gtgactctga gacaaatcat agtccatagt gatgtctcta gagtaactac
    28321 gcctaatatt acgaggcatc atattaatct atcagcacta gtacctaaac tagcatccct
    28381 ttcgaatatt ttttcttata taataaagtt tgctttcact cctctaatct caccaaatcg
    28441 actggcttgc gttgtgtgat actaggaact gattggttta gaacgacttt tctattgtaa
    28501 tcatattttt cgccatcctc gttgtcttct aatccttcaa tgaatgatcc ctaatgtgtg
    28561 tattaaataa tttaattttt ttgttcctat ttatttaaca
//
LOCUS       DAZULR010000036        25188 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.036, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000036 DAZULR010000000
VERSION     DAZULR010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25188
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.036"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..577
                     /locus_tag="ACG8ZV_001818"
     CDS             <1..577
                     /locus_tag="ACG8ZV_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HFS4997151.1"
                     /translation="KLASRIAIMSEGRVIQFDTPENILRHPANDFVEELIGEDRLLQA
                     KPNATRVGEVMLNTAITITPEKSLQEAIKLMREKRVDTLLVTDNSNVLKGFIDVETLN
                     KKRGKVSSVGDILNKHVFYVKESAYLRDTLQRILKRGLKYVPVVDEQNKVVGILTRAS
                     LVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            581..1222
                     /locus_tag="ACG8ZV_001819"
     CDS             581..1222
                     /locus_tag="ACG8ZV_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4997152.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            1219..2136
                     /locus_tag="ACG8ZV_001820"
     CDS             1219..2136
                     /locus_tag="ACG8ZV_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HFS4997153.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            2133..2804
                     /locus_tag="ACG8ZV_001821"
     CDS             2133..2804
                     /locus_tag="ACG8ZV_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4997154.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(3345..3833)
                     /locus_tag="ACG8ZV_001822"
     CDS             complement(3345..3833)
                     /locus_tag="ACG8ZV_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HFS4997155.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(4034..4300)
                     /locus_tag="ACG8ZV_001823"
     CDS             complement(4034..4300)
                     /locus_tag="ACG8ZV_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HFS4997156.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(4300..4563)
                     /locus_tag="ACG8ZV_001824"
     CDS             complement(4300..4563)
                     /locus_tag="ACG8ZV_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFS4997157.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            5084..5224
                     /locus_tag="ACG8ZV_001825"
                     /pseudo
     CDS             5084..5224
                     /locus_tag="ACG8ZV_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            complement(5366..7189)
                     /locus_tag="ACG8ZV_001826"
     CDS             complement(5366..7189)
                     /locus_tag="ACG8ZV_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFS4997158.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(7786..10491)
                     /locus_tag="ACG8ZV_001827"
     CDS             complement(7786..10491)
                     /locus_tag="ACG8ZV_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HFS4997159.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(10797..11744)
                     /locus_tag="ACG8ZV_001828"
     CDS             complement(10797..11744)
                     /locus_tag="ACG8ZV_001828"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HFS4997160.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            11934..12203
                     /gene="rpsN"
                     /locus_tag="ACG8ZV_001829"
     CDS             11934..12203
                     /gene="rpsN"
                     /locus_tag="ACG8ZV_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HFS4997161.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(12379..12741)
                     /locus_tag="ACG8ZV_001830"
     CDS             complement(12379..12741)
                     /locus_tag="ACG8ZV_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFS4997162.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(12752..13873)
                     /gene="alr"
                     /locus_tag="ACG8ZV_001831"
     CDS             complement(12752..13873)
                     /gene="alr"
                     /locus_tag="ACG8ZV_001831"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HFS4997163.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(13889..14239)
                     /gene="acpS"
                     /locus_tag="ACG8ZV_001832"
     CDS             complement(13889..14239)
                     /gene="acpS"
                     /locus_tag="ACG8ZV_001832"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HFS4997164.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(14369..15880)
                     /locus_tag="ACG8ZV_001833"
     CDS             complement(14369..15880)
                     /locus_tag="ACG8ZV_001833"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFS4997165.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(16202..17554)
                     /gene="murF"
                     /locus_tag="ACG8ZV_001834"
     CDS             complement(16202..17554)
                     /gene="murF"
                     /locus_tag="ACG8ZV_001834"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HFS4997166.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(17707..18783)
                     /locus_tag="ACG8ZV_001835"
     CDS             complement(17707..18783)
                     /locus_tag="ACG8ZV_001835"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HFS4997167.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            18979..20724
                     /locus_tag="ACG8ZV_001836"
     CDS             18979..20724
                     /locus_tag="ACG8ZV_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/UbiB family protein"
                     /protein_id="HFS4997168.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(21004..21441)
                     /locus_tag="ACG8ZV_001837"
     CDS             complement(21004..21441)
                     /locus_tag="ACG8ZV_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HFS4997169.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(21425..22798)
                     /locus_tag="ACG8ZV_001838"
     CDS             complement(21425..22798)
                     /locus_tag="ACG8ZV_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997170.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(23120..23608)
                     /locus_tag="ACG8ZV_001839"
     CDS             complement(23120..23608)
                     /locus_tag="ACG8ZV_001839"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4997171.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEVFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(23630..24232)
                     /locus_tag="ACG8ZV_001840"
     CDS             complement(23630..24232)
                     /locus_tag="ACG8ZV_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFS4997172.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
     gene            complement(24301..>25188)
                     /locus_tag="ACG8ZV_001841"
     CDS             complement(24301..>25188)
                     /locus_tag="ACG8ZV_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HFS4997173.1"
                     /translation="RNLDSRTRFEQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYY
                     WVKKLDKPDKYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMG
                     LTCQIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPIL
                     DLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLK
                     ENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKR
                     IKLKLNGLSPVEYRKQSIK"
BASE COUNT         7216 a         5316 c         4606 g         8050 t
ORIGIN      
        1 taaactagca agccgtatcg ccatcatgag tgaaggccgt gtgatccaat ttgatacacc
       61 agaaaatatt ttacgtcatc ctgcaaacga tttcgtagaa gagttgattg gagaagatcg
      121 cctactacaa gccaagccaa atgcgacaag agtcggcgaa gttatgctaa atacagcaat
      181 cacgattaca ccggaaaaat cattacaaga agcaatcaaa ctgatgaggg aaaaacgtgt
      241 agatacgttg ttagttaccg ataattcgaa tgtattaaaa ggatttatcg atgtagaaac
      301 gttgaataaa aaacgaggaa aagtatccag tgtcggcgac attttgaata aacatgtttt
      361 ttacgtaaaa gaatccgcct atcttcgtga taccttgcaa cgcattttaa aacgcgggct
      421 gaaatacgtg ccggtcgttg atgaacagaa caaagtcgta ggtatcctga ctcgtgcatc
      481 attagtggat atcgtctacg atgtgatttg gggagaagat cccgcaacta ctgatgttgc
      541 agagtcagct actcctgaag aatctaagga ggtctgacct atgcagcagt tttttcatca
      601 gcacggttca gaaattctct caaaaggttt tgaacatctt tatatttcag gacttgcttt
      661 gatcattggt atcatcattg ctgtaccgct tggtgtctta ctgacacgtt ttccaaaagc
      721 tgccacgatt gtgattggct taaccagtgc cttgcagaca atcccttctc ttgctttatt
      781 ggcattgatg atcccgctat ttggcgtagg taaattacct gcgattatcg cactctttat
      841 ttattcatta ttgccgattt tacgtaatac gtacattggg atgaaaaatg tcgattggaa
      901 ttatcgggat gtggcaaaag gcatggggat gactgagttc caatccattt tttccgttga
      961 attgcccatt gctatgccaa cgatcatggc tggtattcgt ttagctgccg tttacgtgat
     1021 tgcatgggct acacttgcct cttatatcgg cgctggtggt ttaggcgatt tgatttttag
     1081 tggactgaat aattaccaac cagatctcat tttggcaggt acgatccctg taacaatttt
     1141 agcactattg gctgattggc ttctaggtct cttggaacac cggctgacac cgatcgcact
     1201 tagagaggag aatgaagaat gaaacgtata ctaaaaatga ccatggttct tttctctctt
     1261 cttatacttg cgagttgttc cttccctggt cttgccagca atacagatga agacaccatt
     1321 tcgatcacag gtggaatcac ttcagaagca cagatcttag caagtctagt tgccggaatg
     1381 gttgaacatt atacagataa aaataccgca atcatcaaca atctggctac tacaactatc
     1441 aaccatcaag cgatgatgaa cggagatgct tcaatttcag cggctcgcta cacaggaaca
     1501 gatttaacga ctacattgaa ccttcctcct gaaaaagatc cgaaaaaagc gtttgctacc
     1561 gtgaaagatg aatttgagaa aagatacggt caaacgtggt tcccgtccta tggttttgaa
     1621 aatacgtatg tctttcttgt tcgaaaagac accgcacaaa aataccatct atctaaagtc
     1681 agcgatctga aaaatgtagc ggatgaatta gtagctggtg tagatacttc ttggatcaat
     1741 cgtaaaggag acggttatga cggcttccaa gaaacttatg gcttctcctt caattcgata
     1801 ttacctatgc agattggact tgtttatgac gcagtcgaag caggaaaaat ggatattgtt
     1861 cttggctact ctacggatgg acggatcgcc agttatgatc tagtcatgtt ggaagatgat
     1921 cgtcaattct tcccaccata tgatgctgct ccagttgtag acaacaagat attagctgat
     1981 acgcctcatt taaaagaagc cttaaataag ttaggtcata ccatcagtac ggaaaaaatg
     2041 caggaattga actacgaagc agataataat ctagtggaac catcagtagt agcacaacgt
     2101 ttcttacaag aaaaccacta ttttgaaggg aagtgaagca attggataaa atgaatgtct
     2161 ttcaacaatt tttctattat ttccaggaaa atggctccta tatctttgca caatttatcc
     2221 gtcacttcct gatttctatc tatggtgtcc tctttgcagc agttgtcggg attccggttg
     2281 ggatcatgat ttctaggaga cgtaaattag caaactgggt gattcgtttg gcgaatatca
     2341 tccagacgat cccttctcta gccatgatct ccattttaat cattggatta ggcctgggag
     2401 tcaatgtcgt gattgttact gtatttttgt attccctctt accgatcatc aagaatacgt
     2461 ataccgggat gatccaagta gacaaaaaca tccttgatgt cggcaaaggc atggggatga
     2521 ctgctagaca acgactattc atggtagagt taccactctc tgtttctgtt atcatggcag
     2581 gcataagaaa cgcgttagtt gttgccatcg ggataaccgc gatcggtgca ttcgtcggtg
     2641 ctggtggtct tggagatatc attatccgag gaaccaatgc aacagagggc acatcgatta
     2701 ttttagcagg tgcattgcca actgcattaa tggcgatcat cacggactgg cttttaggta
     2761 ttttggaaag acggctagat ccagccagcc gtacatcacg ctgatgttat tgtaaaaaac
     2821 aaaagcttct gcgaccattt gttggtcgca aaggcttttt tagttctgtc atttttaagg
     2881 caataatcca ctctgattct tccctcctta tgggcaaaga gttgcttttc ttagctattt
     2941 atccattccg tatactccaa cttcatactg ccaacgggtt catatctgca tccaccgact
     3001 aagttttttt cttatccgct aaggcatttt gccaatccat tttcccatca ctcgtcatgg
     3061 aattcatacc acatgatctc taaatactcg tctgcttgtt ctttgaattg ggcatcaatt
     3121 cttacatcct ttggcgtggc tttcatttaa gccttttcca tcagtcctcg attgttcgat
     3181 gccttcagct gcatcatcaa aactggtgac tgccgtatcg gtaacttcga tcatctttta
     3241 tacaatcggg aacttgccat cctcatcctt ggctaaaaac atatctagcc attccagctt
     3301 ctcgccatgg gaggtttgcg gttcctaaaa ccggtacacg attcttatgg actgcatccg
     3361 tcgcaactag acttggcgat acgatgatcc ttcaccagaa gagcaccccc gtaaaccaat
     3421 tgatcgatat attgccaata agaaaagaca ttggcgtaaa agatatcgat ccctcgtgat
     3481 gcattgccgt tgatactgct attcatggcc gaaagcgcca cgactttaac ttcttccgtt
     3541 tgagtgacat tcatgttcgg caatgtcgct ttggataccc gctctgctaa aggaacgaca
     3601 ctggtattgt atttcgtatc tgtatctttt ccaaaagacc atgccaacga atcctctggg
     3661 aaccaataag acgactccgg ttgattgtcc attgcttttt tcaacatact tttggctgtt
     3721 tctcgataaa cgacatttcc aattgtcttc gcctcacttt ggcgataatc gatggtcgtt
     3781 gccactgcca acactaacaa cgatgctcca attttactga ttttccttgt cacacttctt
     3841 cctccttgtt ttacataaac ccgtcaacat tccattccta aactcaaaca atgacccttc
     3901 aaaggtggag atataggaac aaattaaaga aatcatgcaa taaatccaag aaggttggtt
     3961 ttagaacaaa aaaagagtct cctttttggg gagactcttt gttaactatc taaaaaggtt
     4021 ggctcttctc acttcactca taatgtgtcc aggcagaata aatttctaca actttatttt
     4081 cctcatcaac tttgtaaacc actcgatgct gtctattcag cctgcgtgag tatctgcctt
     4141 catgtgtagg tctcagcttt tcaaaagact gcgtgggcat atatggatct tccttcaatg
     4201 tctgaatcac ttcttcaaat tgtttcttta aattcgtttg cttgattttt cttaaatcca
     4261 ctttcgcaga gtttttgatt gcgactgtat agttactcat caaagagctt cccaatcaat
     4321 atcatcgata ttcgtaaagc tactgtcgtc tttttcgcgg tctcgtactt tatctaaagt
     4381 acctgtttgc tcaagaaaaa gggtttcttg aatcgctctc cagtcttcca gcccaatcaa
     4441 tacagcattg tttccactac gatcactaat aatctcgatt tcagtatgat tttcatttac
     4501 ctctttcaat aactgataaa aatttttacg agcagtgcta ggattcatcg ttgtattagc
     4561 cattgtctct cctccttttt ctgatataat tatagcgtac ttgattaagt acgtcaaaaa
     4621 aatacaataa agcacttaaa ttcagcaaac ttttcctctt ttttacatag agaaaaagac
     4681 ccctttttag ggaggatctt tgtccacgct cacttcttac tcctttacga ctagcggtag
     4741 ccaaacgtaa agtaattggt aacaacgtat catctttagc aaaggtcgaa tccaaagcct
     4801 gtgagtctat gcaacaacac caatacacga aggttcctcg ttgcagtgtg acttgattga
     4861 tatcttgaat aacctgagga tacgcacgaa agatttgtaa cggttattca aaactgattt
     4921 tggccgtcaa gtcttctact gcctcaaaaa tgattgcctc tttcgtctcc tgtcattcat
     4981 gttcactatc gatttgatac ttgcttagac cgttgggttt gtgaatcacc aattaaaaat
     5041 ggcactgagt tatggtaaca aaaaatggtc acttgacgag gctgagattc ctacttatga
     5101 agacacatgg cacttaagag tcgaggtaaa ggaagaagct gaaaatatag gaggctgtac
     5161 attatttggc aaaggattcg gaaattatga tcaagacatc aaaatcaaaa tgttttacag
     5221 ctaaatagga agaataataa catttcatac gctgttccca tctttaatgg cttatagagg
     5281 gcacctttag ctgagaataa gacaaaacag accctctagc ttcaattaag agctagaggg
     5341 tctgtttttg attttaaaac ttggtttatt tcttcaaatg gtagctatag gtgctgacaa
     5401 cgatattttc acgccaagac aatcgcaatc ttaaccgcaa acttgtttgg ttatggagaa
     5461 tattctgcca gcgtctgttt ggtacaaatt gaggaatcaa cacagtagtt gtatagtttt
     5521 gtttcgctgc atttttactt acgatatcta cataacggat aattggattt tcaatcgagc
     5581 gataagaaga gtggacgatt gaaaaacgga catctgggaa atgcttttta aattctgctt
     5641 cgatttcttt ttctttttcg acatcttcgt ctagcgaaac atgcatcgca acgacataat
     5701 caccgatcga acgtgcgtaa ttcaacgcac cgatatttac ccgtgtcaca ttcccgacta
     5761 atacaagaac ggtattcccg tcataatcat gtagttttgc atcattttct aaacgaagct
     5821 gttctgctac ttttttataa tgatcatgga tcttataaaa aatgaacata acgattggca
     5881 taatgatgaa gaaaggccaa atgtccccta accgatagac aaacaaaatc gcaatgattg
     5941 catatgagat gaacgcaccc gtaatattgg caatcgattt gcttaaccat ctttttcctt
     6001 cttttttcca tttgacgacc atccctgttt gagataaagc aaatggaatg aacacgccga
     6061 tagagtataa cggaatcaag cgttctgttg agccatggaa aataaacagc aatacgatcg
     6121 aacctagcgc tagtgtgata atcccattgg aatagcctag tcgatcccca cgatcttgat
     6181 acatgtgagg catgaattta tcttttgcca gattgtatgc aagaactgga aaagcagaaa
     6241 aaccggtgtt agcagcaact gctaaaatca gcgctgtagc aaattgaagg acgtaataca
     6301 aaataccatg tccaaagaca gctttaccaa tttgagacaa aacagtgact tctttttcag
     6361 gaacgatccc ataccaatag ttgataaatg tgatccccac gaagaagaaa cctaagatca
     6421 atgccatcat cgtcaatgta gcagcggcat tttttgctct tggcttctta aagaatggta
     6481 cagcattact aatcgcctcc accccagtta aagaggaaga accagaagaa aatgctcgta
     6541 aaatcaaagc gatagaaaca cccggcacag ccgctcctgg aagtgcagta gcttgcaatg
     6601 gcacagcacc tgtcacgata ttatataaac caacaacgat cagtaacgag atcacaagga
     6661 taaatgtgta caccggaaat aataggaacg atgcagattc cctcagccca cgaagattca
     6721 gcatcatcag tagcaaaacg attgtcacag aaatagcgac ttgatgaccg tagagtgctg
     6781 gcaccgctga tgtgatcgct tcagcacctg ctgagacaga tactgctact gtcaacatgt
     6841 agtcgatcaa taaagagcca ccggaaatca agccagcatt ctttccaaga ttctcactgc
     6901 tgacgacata tgctcccccg ccatgaggat aagcatggat gatttgacga tatgatagcg
     6961 ttaatgaaat caataaaata ataacaaaag cggcaatggg tagcgaatac cagatggctg
     7021 cagcagacaa agcgactaaa acgacaacga tttgttccgt accatatgca atagatgata
     7081 acgcatcaga cgacaataat gccaaagcag caaatcgggt taatttgtgc tcatcatttt
     7141 cagcagattt taaaggctta cctactaaca acctttttaa gtaatccaat ttctaaactc
     7201 ctttacacac aattttactt caagttttat agtcgaaaat ttatagtaaa caagatgtta
     7261 tagtacgctc actgacctta aaagtcaata aactttaaga aaataattgg aaaaaaacag
     7321 aaaaatatca agcgcttttt caaacgcttt aatacagcaa aaatctaaca ttttttatgg
     7381 gctttttctt tgaattctat aataaaagga tagaacttga cttagaaaat caagttctat
     7441 cctttttgat atcttaactt ttggaagaga gatgtaaggc tgctttctac ccatcattct
     7501 tactactcga agcatagcgc agttgtcaca acctcttgat aaacggtgtt taaaagcttg
     7561 catctgcggt aataagccca accaaattaa aaacataaga agctgttttt atttggtcgt
     7621 tcttattact tgatgcagag cagctttttt acaacctctt ggtacacggt gttcaatcag
     7681 ctgaccctcg gtattagctc aaaaaaacgg caaaatatga ggaactattt ttccattttt
     7741 ttctctaata ctcaggtcaa aacactgatt tcacaacctc tttttttaat gaaaaatatg
     7801 gctctcatgc gccgcttctt tgaatttcgt cattttttct tcgatgaacg gatagattgc
     7861 cgttcctacg attccaaaga caacaaacaa accgatcatg atccagattg ctttcgtagc
     7921 atttggccaa taaattcctc ctgcagattc ccgtaacaag tttaccgcat gagtaaatgg
     7981 caagaacgga ttgatcattt ggaagaattt ccctgagact tggatcggat agttcccgcc
     8041 tccgccagag atcgacagta ctaagatgat aatagcgatc cctttaccga cattatcgaa
     8101 taatgcagcc aagacataga cgatcatcat gaacgctaag gcgatcaaga cagcaaatga
     8161 cacgctgtag accggatttt ggacatctac tcctagtaag aaaatattcc ctaatgtaac
     8221 gatcaagctt tgcgcaatcg ccattgtcaa aaatgtcagc atacgagcaa cgaattgttc
     8281 tcgtttcgta aaattgtttc ggtctttctt tcctaaatag tattctgtcg tagcaacact
     8341 tgaaagaaga acagcgccga cccacagaca tagtgcagta taaaacgggg tgctagctga
     8401 accgttattt gcgattggat aaagcgcatt ggtttgtagc tcaacaggtt gtgtaaagaa
     8461 gtcactttct tttgttgcgt ctagtttcaa taatttgatg acttcgccta gatcgacttc
     8521 ttgttcgcct tttcggatcg cgtctgctgc tttttggata ccagctttga tatttggcca
     8581 gtcattgttg atcaagtccg cagcagcgtt cacagctgtt tcgacttctg gcattttttc
     8641 atttactgtt gtcaatgtac cggtgatttc attttttagt gctggccaat cattttggat
     8701 aaaatcagcg gccaatccta atttttgctg aatgatcggt aattcattgt tgtataggtc
     8761 tgccccttca ttgatgccat tgacgatggt atccatattt ccattcagca ttgtattggc
     8821 atcatggatt tcttgtccaa ttgcaggcat ttctttttga tatttttcta aaattgccac
     8881 tgcattcgtt acagttgctt tcgttgagct gagaagcgaa tcaaagtcga tctggtccgc
     8941 tttgctcagt gcgccttgtg cagtcccaat cgtatcgatg acttggtcta gtagagaagt
     9001 gacagtggaa ctgatttgac ctgtattgat accagcaatg atgccattga tattattaac
     9061 aacggcatca atttgatcta gcaattcatc aatagccttc gtgtcttcat tttgaacagc
     9121 tgtgttcaaa gcagataggc ggttttgcag attgcttagc aagggtttta attgatttag
     9181 ctgatcaata attggctgta atttcgtatt tccagcactt gtttgcaatt tagtcaggaa
     9241 ctcgaccagt ttatcgattg cattttgttg ttgagatatt ccgtcaataa agccgttcaa
     9301 tacattgctg atgtttttct tttcatcatc agtcagctta ccatcttcaa tagctgttct
     9361 tacagtatct attaacgaac ctgtcgttgt tgccacttgt ccaattgact tcaatgtaac
     9421 atctacactg tttgtgatgc ttggtatcgc atctttcagc tgagaggcac ctgattttgt
     9481 ttggtttgct agatcacttg cctgattttc taaatttttc acatctggca agatatcttg
     9541 tacttgttgg atgatcgtca agccttgttt tgcttcatcg attccttggt tcattgtctc
     9601 ttggatcgaa gcaaaatcgc cgtcgatctc tgctagttgc ttaccggcat tttggatctc
     9661 tgggattttt tcttgcaaat caaggatgat ttttgcttga tctttcaact caggcatttt
     9721 gtcattcaat gcaacgactt tttcacccat ctcatctact ttagggatgt aatccacgaa
     9781 ttcatttgct ttattcagtt tttccttgat ttcaggtagt tgactttgta attcgaggac
     9841 ttgttttgtg tagccgtcga tcgtgtccaa attttcatct gttgataaaa tcatatcttt
     9901 aactttattg atacttacta ggttcgtatc gatgtcgtaa cctatctcat tgaatacttt
     9961 caataaagtc gaactggctg ttttgataaa ttcatttgtg atttgcgatt ggatcgaact
    10021 tgctccttta tcggtgattt tcggtgcaat cgcattgatt ttttcattta ccgtatattc
    10081 gatttttggt ttcttgatat caccactagt aaaactcagc agatcttctg agaaatcctt
    10141 tggcaagtaa atacctgcgt aatactttcc ggaacggact ccgtcttcta attgttcttt
    10201 tgaatcaacg aattgccatc ctaattgttt atttttatga agcgattcga tgacttgctc
    10261 cccaatggcc acttctttac cttgaaactc tgctggcttg tctgcactgt aaacagcaat
    10321 tggcagctct ccagtatttc catatggatc ccataatgct ttgatgttaa accacgcata
    10381 tagcgaaggg atgatcatga tcgcgatgat cagaagtgtt gcaatcgggt ttttgaaaat
    10441 ccgtttccag tcaagcaaat ataatcgaag cgtatttttg attgactgca tagttctccc
    10501 ccttcttctt ttttcagctg aattacttta ccatgtattt catacttttt tcaatcggct
    10561 tttttcaaaa aagtcgaatt tttggacata tcacggcaat tgtctcattg taatctctta
    10621 catattgaga aataattaag gattacagcc tttactttat catgaaataa aagggaaaga
    10681 taattttatg ccaaagtttt tatctattat acgtatacgc aaaaaagcta aaacattttt
    10741 tgtctttgcc cctacaaaaa tgtttcagct tttttcgttt tttattcctg tatttcttat
    10801 ttttcgaatg acaggatgat tttcccagca ggaggatgtc cttcaactag ctgatgtgct
    10861 tggatgacat gcttaagtga agcagacaga ttcattgaaa taaaaacatg aaaggctcct
    10921 ttttggtagg ctttgattat gccagcaaag gcttctgcat ctagatattc ctttcttgga
    10981 acaaacgatt cataaaagcc ttcctttttt tgccgcaaat ctagatctgg gaggtcattt
    11041 aatgcaacat acctgccgcc tggtttcatg atctggatgc cggtttctcc tttgatactt
    11101 cctttcgtcg catcgattac aaggtctgcc tgatcagcaa attgcagacc tggatttgtt
    11161 ttatcataag cagcaaatgc tgaagctcct aattttttta ccttttcctc atttttactg
    11221 gatgcactgg ttaagattcg gattcccttt tcatggagaa gctggatcag acttgacccg
    11281 accgcacctg atgctcctag tatcattaca gtatctgtcg gctggatttc cgtcaaatgg
    11341 ttgattagat tataagccgt aattcctggc gtgaccattc cggctgcttc ttcccaactc
    11401 attttatctg gaatttttgc tacttttgct gatggcaaca cgacttcttc tccgtaagtc
    11461 ccgccgactg catggacagc tactcgatca cctacatgaa cagttgtgac atctgaacca
    11521 atctctgtca caataccagc gccatcatta cctggtacat aagggaattt caatgttcgt
    11581 atctctttca tttctcctaa acgcaaggca acatcataag gattcacact gaatgctttt
    11641 atttctacac gaacatgtcc agaaccgact tctctgggat gagcatcgat ttcttcaaaa
    11701 acatcttgtg cttctccgta accgttaatt gcaaatcttc gcatggtcac catctccctt
    11761 tttctttaag tttacgttta tgcctttatt ttgacaaaaa aaatgtcttt tcgttttggc
    11821 gcatgattca aaacaaaata gttgtctttt ttcgcgtaac gtgttaaatt atttatctaa
    11881 aagcgtaaag attacgattt acgctaataa aaaataattg gaggaatttg ttgatggcta
    11941 aaaaatcaaa gattgccaaa gcaaaaaaac agcaagaaac gattgaacgc tatgctgctt
    12001 tacgccagga attaaaagcg caaaaagatt acgaaggctt gcgtaaactt cctttagatg
    12061 ctcgtccaga acgattgaaa aatcgtgatt taatcgatgg acgccctcgc ggatacatgc
    12121 gtaaattcgg gatgtcccgt ataaaattcc gtgaattagc acataaaggt ttgattccag
    12181 gagtaaaaaa agccagctgg taatccaagt ctggctgtaa tgtaaaggag gagggcgcat
    12241 ggaccactcc ttggatcatc aaaaaagata cgttcgcttc ttctagcaga aatgctggta
    12301 ctagaagcag acgtatcttt ttttacgcac agctggtcct tttttatatg taaaggctgc
    12361 atggttactt cgctatattt atttagtaac aggagtcagt gcttcgatac ccacactaat
    12421 tttcaatgct cggtcaactt ctgccataat gggtcgatcc aaatggcaga ccttttcttt
    12481 caatcttgat ttatcgatcg ttctgatctg ctccaacagg ataacggagt ctctttctat
    12541 tcctgttcca gtagctttga tcccaatgtg agtcggaagc ttaggtttag ccatttttgc
    12601 cgttatggcc gcaacaatga tcgtcgggct aaaatggtta cctagattat tttgaataac
    12661 caaaactggg cgtgttccgc cttgctccga tcccacgact ggagaaagat cagcaaaata
    12721 aatatctcct ctttttacca taggatcctc cttattcttg atattctctt ggtatccgct
    12781 gtcctaatcc gcaagccact tcatagtgga tcgtacctaa ttgatctgct atatcctgca
    12841 tagtgatttc tttgtctgca tttttgccga taagcgtcac ttttgttccg acaggaaatt
    12901 cttgaggcaa tcggatcatc agttgatcca tacatacacg cccaatcgtt tcacagtagt
    12961 tcccttctac caatagagaa aaaccctgca tctttcgtgg ccagccatct gcataaccga
    13021 tcggtatcgt tccgatccac tctgcttcag gagtgatata tgtttctcca tagccgattc
    13081 cttcacctgc tgggagtttt ttgacttgaa tcaattcaga aaccagctca agtgctggct
    13141 gcaatggata aacttccggt agtgcgtgcc cagagggatt aagtccgtac attgctactc
    13201 cataacgaat catattgccg attgtttcat catgccataa agccgttgca ctattgctga
    13261 catgtacata tcgaggaagt tcgggaagtt ttttcagcac ttctataaag cgttcttttt
    13321 gcagattcca atatgtatca tctgcctgat ctgctgtaga aaaatgggta aataaacctt
    13381 cccattctaa tacacgactt tctttgatga atgcagctgc ctcttttact tcttcaggtg
    13441 tacaaaatcc gatacgaccc atcccagtgt ctgcttttag atgaatcgaa agaggcgtct
    13501 ctagcttact tttctctaaa acagcagctg ctgcttgcaa ccattcccgt gtacctgcag
    13561 ttactgataa atcatgagca acagctacag tcagtgcgtc gtaaggaacc atattcaaga
    13621 taaggatggg ctgagtaaat ccagcttctc tcaactcgac tccttcatct aaatttgaaa
    13681 cacaaaagcc cgaagctcca cctgcaactg ctgcctcagc tgtttcaata gctccatgac
    13741 cgtatccgtt cgcttttact actgcaaaca attcttttcc ttgcggaagt cttgcaactt
    13801 catttgctac attttcagtt atagcttttt tatgtatcac tgctttcgtt gggcggtgcc
    13861 aagcgacaac catcgttttt ccttctttct agtcttccaa aataatttgt gcaaaagctg
    13921 tttcatttgt atgagtaata ctgacccata cattgccttc atgaggtgaa cgcgtcacaa
    13981 caggctgacc attttcattt tttaaaatct cgacatcttg aaaggtaact tttccgatcc
    14041 cagttcccca agctttagag aaagcctctt tgcaagcgta acgcccgcct aaaaattcta
    14101 cttggcgatg aaaaggcaag gactggaata gtttcatttc atcagaggtc aagattcgtg
    14161 caatgaattt tggtttttct tcgatcagcc gagtgatcct aggaagttcg actgcatcga
    14221 tcccaattcc ttttatcata tgcttttctc ttttcaataa atttagaaca ctctcattct
    14281 accaaattat aaccattttg ccacaaataa gtccacaaat aacaaaaatg aaagtttctc
    14341 ttaaaaaaga gaaactttca ttttatgttt aatcgttatt tgaacggatt acaaatccgc
    14401 gttttttatc attgtgacgt ttaccgccat ctttttggct gttattattt ttgctataac
    14461 cgccttttga tttgtttcca cgataattac cgccgtcacg acgattacgg ttgtttccgc
    14521 caccacgttt gccattttta ttgtatcctt ttttctgcat tggcaatggg cgttctggtg
    14581 tgatcttcac tggcactgca tcagctggat cttttgctgt cgtttttagc aaaagtgcaa
    14641 ctaaatcttg tgcagaatat tcttctaata atttatctgc tgtttgcagg tatttatcta
    14701 gaccattttc tgcaagtttt gtttcgattt gttcaactgc agcacctaat tgacctttga
    14761 atgcttcttt ttcggttggt ggacgtaaag tcgtcatccg ttttttcgtc aagttttcaa
    14821 tcacatgcaa gtagtccatt tcatttggtg taacgaaagt cacagacata ccgccttttc
    14881 cggcacggcc tgtacgtccg atacggtgaa cgtagctttc tggatcttga gggatatcat
    14941 agttgtacac atgagtgaca cctgaaatat ctaatccacg tgcagcaacg tctgtcgcta
    15001 caaggatatc taaatgaccg ctcttaaatg aacgcaatac gctcattcgt ttttgttgag
    15061 acaaatcgcc atggattcct tctgcacggt aaccgcgtgc ttctaatccg cgtgccaatt
    15121 cgtctacacg gcgttttgta cgtccgaaga cgattgttaa ttcaggtgtt tgaacatcaa
    15181 acaagcgagt catgatatcg aatttttcgt attcttttgc gcggacatag tattgatcga
    15241 tcaagtcagc tgtcatttct ttcgctttga tcttcacatg atgtggattt ttcatgaatt
    15301 taacgccaat attcttgata gctggcggca tcgttgctga gaaaagtaat gtttgtcttt
    15361 gatcaggaac ttgtgaaatg attttttcga tatcttccaa gaagcccata ttcaacattt
    15421 catctgcttc atccaaaact aatgtttgaa cggttccaag tttcaatgtg tggcggttaa
    15481 tgtggtcaag catacgtcct ggtgtaccca caacgatatg tggacgatct ttcaagccac
    15541 ggatctgacg gccaatatct gctccgccgt aaacggcttg tacacgtact tttttgtcgc
    15601 gccctaaacg atataattct tcttgtgttt ggatagctaa ttcacgtgtt ggtgcgataa
    15661 ctaaaccttg taattcgtga cgatctggat cgattttttc taacattggt aatccaaatg
    15721 cagctgtttt ccctgtacct gtctgtgctt gtccaataac gtcttttcca gctaatgcta
    15781 gtggaatcgt ttctgcttgg ataggcgttg cttcttcaaa accagcgcgt tcgactgatt
    15841 tcaacaattc tggtgataat tctagttctt taaatttcaa atgaatcctc ctatatggtt
    15901 gttaactgag gatgtagctt ttttgctacc ccgtcgattt gttcggtcaa agtgtattgt
    15961 ttctttttga cagtggccac gcacgttttt atccattctt agcccctgtg gcaccaccga
    16021 aaaatcactt tgcgaagttt aggcattaga aaagccaaac gggtcgcgtt cagctttatc
    16081 attattatga catctggctt caacaagttg tttctatggc aaaaccagtc caatttctct
    16141 tcatctttcg gcaataggtt attctaacat agtttttcgt tttctgcaag tttacagatt
    16201 tttatttcat ttgctgaagt tgttctacca cttcaaataa gcccatgctg ttgctgcctt
    16261 ttagcataat actatctgtt gcttcaagat tttgtttgat agcatcaatc aatttattct
    16321 tttctttttc aaaatagaac acaggtagtt gggggtattt ttggttcaat tcttctttta
    16381 gtgcatgcat ttgttcccca taaaggaaaa tcatggcgaa tttctcagga tcgatatgtt
    16441 cactcatttg cgcatgcata tttaaagact ctttccctaa ttccagcata tctgctaaca
    16501 cagcgattct gcgtcctttt gttggcagat ttttaaaagt atctaatacc agtcccatgg
    16561 ctgttggatt tgcattgtag acatcgctca aaatagctgc accatttcct gccgttagcc
    16621 attcggttct gttttgagtg atagaaacat gggcgagccc ttggcgtatc tcaggtatgg
    16681 acagtccaaa gaagcgcccg atcgtatacg caatcaaagc attcgttaca ttataacttc
    16741 caggcagcgg gatcgtaaat gtttctcctt ctactacaaa atcggtttgt gcttttcctt
    16801 ttgctgtcac ttccgcatga acatcgccat ttccaatacc gaatgttgtg actgtttgta
    16861 ctaatgttgc cgttaaaggt gtcagcaacg gttcatctgc gggcacaacg agtaatccgt
    16921 ctgatacaag tccgtcagtg atttccattt tggctttagc gattccttct cgcgacccaa
    16981 gattttctat gtgtgcttca ccgatcattg tgattgctgc agcttttggt tgagccataa
    17041 gtgaaagttc cgtgatttca ttggcgtgat ccatgcccat ttccaaaacg atcttttctg
    17101 tatcttgggg catgtgcaaa atcgtgtaag gaagaccaat attattgttg taatttcctt
    17161 gcgtcttata tgttttgtat ttttcagaca agacagacgc ggttagatct ttcgtggtgg
    17221 ttttaccatt gcttcctgta attgcaacga cttctgcgcc tactttttcc aagtaatagg
    17281 ttgccaattg ctgcatggct ttcaaaggat ctgctacagg aataactgga aaattttttg
    17341 gagcttgttc aacaggcaag ctccaaaatg aagcagatgc tccgtttgtg atcgcttgct
    17401 ggataaattc atgtccatct cgcgtaccag caagaggaac gaataaactt ccttcggtta
    17461 tcttccggct gtcaaattcg acattggtaa tctttgtcag tgcagagcat tcgctgccca
    17521 cggcttgtgc aatttcttgt attgttagat tcattgagat ctctcctaaa aaaggttgtg
    17581 aaaaaagcgt ttggcctaaa cggcgggttc gcatgactct cacttccaag taaatttctc
    17641 tattcgtatt tagaagctag aatgaacgcg gttacgcaat cactccagcc tcttctttat
    17701 ttctctttat tcattttttt caaaaaaaga ttgacgctga tggtatcgat tcattcctaa
    17761 ctggatcagt tcttcaatca aatcaccgta tttcaagccc atattttccc ataagagtgg
    17821 gtacatactg aactccgtaa atcctggcat agagtttaat tcattcagga ataattcatt
    17881 tttatttgtc aaaaagaaat cgcaccggct caatccgctt ccacctaaca tcgtgtaagc
    17941 taacttcgcg tactcttgcg ctttttgata aacttcttct ggcacttcgg ctggaatctg
    18001 catttcgatt ttattattga tatattttgc ttcataatca tagaatgcta cgtcttttac
    18061 gacttcacca ggcaaagtcg tccgaacgtc ttcatttcct aatacagcaa cttcgatttc
    18121 gcgcgcttca attccttgtt caacgattgc tcgagaatca tactgatagg ctgttgctaa
    18181 agcattttgc agctcttctc ggttttctgc ttttgtaatg ccgacactag aacccatatt
    18241 cgccggtttg acaaacatcg gataaagcaa agaaccttca cattgatcaa atactttttt
    18301 aggattttct ttccattgat tcttaagtac tggtacataa ggaacttgcg gcacaccagc
    18361 agcttgtaaa atatacttgg tcatgatttt atccatggca catgcactgg tcaatacgcc
    18421 tgcgccgaca taaggcatat tcaatgtctc taagaagcct tggatcgttc catcttcccc
    18481 gtttggccca tgtaaaactg gaaaaacgat ggctccttct tctttgattt cgcccggatt
    18541 gatcactttt cctgtaaagc cttcctctgt ctgtccactt gggtcccatg aaagatgcaa
    18601 gacatctttg ctggcaggtt tttctgttag taatggacct ttgacccatt gtccttcttt
    18661 tgtaataaat acgagttgaa cttggtaata attataataa atggcattta aaactgaaaa
    18721 tgcggaaaga atggacactt catgctctgc gctgcgtccg ccatatagta aagtaatctt
    18781 caaaagattg tcctcctgta ttctaaatcg ttcagtgatt tactctcata ttttagcaca
    18841 aaacaaaaat aaacgaataa cttatttata aaaaaacgag ccagcttcta aaagaacgag
    18901 cgtcatttat tttttgtcag ctagattatt tgtcccgttt tttataaaaa gttatgataa
    18961 agaaaaggag ggatgatgat ggcgcaaaca aatccacgca gccgcttggc agaaatcatt
    19021 cgagtgttca tcaattacaa tgtagtgcca aactttgtac agcaaaaaaa tcccgaacag
    19081 gtaaaaaaag cctttgaaga actaggcccc accttcatca agataggaca gatgctttct
    19141 gttcgagaag atttgctttc ttctgccttc actcaaacat tcaaaacatt acaagatagt
    19201 gtacctagcg acacattttc aacggtcaaa aagacgatcg aaacagaact ttctctttca
    19261 ttatcagata tattcgatga tttttcaaaa tcgccttttg cctctgcttc tatggggcag
    19321 gctcatcgtg ccaagctgaa gaacggtgac gcggtagtcg ttaagatcca acaccctaac
    19381 atcgccgaag agatccgact tgatcttcaa ctatttgaac gagcgatccc tttgatcaaa
    19441 tacattcctg aaactagcgt agttgatcta aaaggggtac tccaagaagt aaaacgttcc
    19501 ttgatcaatg aaatggactt cttaaaagaa agtcaaaatg gcgaacaatt ctatcaaaag
    19561 aacaatggct ggaaagagat ccgcagcccc aagatttatg acgctttttg ttcgaaaaaa
    19621 gtgatcgtga tggaagaaat gtctggtaaa aacttgaatc atttaatgaa cgccgaaaac
    19681 aaaactgaaa cttttatcac tggaattcaa aacaagcagc tgaaacaaga agttgcaaag
    19741 cttttagttg agaactttat gaaacaggtg tttgatgatg gttttttcca tgctgatcct
    19801 catccaggga atctgctatt ccatgtacta acaaaagaag aacagacaca agctagccga
    19861 aaaactgaaa cagtccatga aaaagagttc ggttcctttg cttttcgagc ctccacttct
    19921 gcagaagacc ctgttgcgcc atataccatc aactacatcg attttggtat gatggggcat
    19981 ctttctgcag gacttaggca aaaactcaca caagccgttt tagcgctgta tacgaaagat
    20041 gcttatcgaa tcgaaaaagc ggtccttcga ctttgtcagc aagaaggctc gtttgatgaa
    20101 agtcggttcc accaagaact gacaagtttt cttgaacagt attatgattc tcctattgat
    20161 gaaatcaact tgcaagaagt attcacacat gtcgtgacga tttgtcatca aaataatctg
    20221 cagttcgatc gtgatatcac gcttttgctg aaagcatttg ggacattaga aggggtgatc
    20281 cgcgtcctcg atcctgaagt ttccctcatg gaagtcgctt cgccttttgc tcaacattat
    20341 tttctcactc atctggatgt agaagataca ttgaaacaaa gcggattaga cttattggaa
    20401 gggatgaagg ctgcgcctaa gatccctcaa cagctccacc atctattaga aatgtggact
    20461 tcgggacaag gaaaagtcaa tttggaattg aaaaagcaag acaaattatt gagcaggatc
    20521 gaaagtatga tcaatcggct tgttttcggt atgattttag ctgcattgat cgtagggtcc
    20581 tccctgcttg tccaagcagc acctgtagaa aacgcagagg tcgtttcctt attagggata
    20641 tttacgtatg ctattgccgc attcgtcatt atttttttgg caatcgatgc attgatccaa
    20701 atgtataaga agaggaaaaa gtagaaaaag gttgtgacag aaagaatcag cttcaagaaa
    20761 taagaagggg ttttacataa attgtttctc aaatttttgt gaaaattcgg cttatttttc
    20821 gaagaggcta cttctgaaac accgagaata aaaaatgtga aaaagctgtt ctgcacccag
    20881 taataagaac aatcaaaaag ggaacatgga acacatttat cctgtttccc tgttcccttt
    20941 ttgatgtatt cgagcataaa taaaatacct tcgttaccta ctatcttctg tacttggtaa
    21001 accttagtca attgcctttt ttaacgcttg acgaaaagac atatgatctt tctccgtaaa
    21061 gggttttgga ccctttgtcc ttatgccagc ttttcttaac tttccactat gataacgttg
    21121 ttctagaagc gtgccgatat tcgcttcgtc aaattctttt ccagagtgat ggaacactcg
    21181 cacacccttc ggcaatacaa gtgaagctaa accataatct tgcgtgatca aaaagtcatt
    21241 cttcttaacc ataccgacga ttttataatc cgcactatca gctccgcggt ctacgtagac
    21301 gatttggaca tgattagcgt attctttggt cgtataatgg tccacactgg tcacgataac
    21361 cacgtcaaga ccataggatt ctcctaattt tatgacatct tcttttactg gagaaccatc
    21421 tccatcaatg aatagcctca ttctttttcg ccttcttcca taaatgataa acagttacta
    21481 atccgctcag taaaagacca acattgatcc attttgccaa gataagcagt tgtacacttt
    21541 ctatcggcac tgattcatgg ttcagcgtga tcaataatag atggattggc tctcccattt
    21601 cttttgctaa aacaaacaaa agcgtcatca ataaaaactg gtggatcaca ctccctttat
    21661 tttgagtagt atacttgaca acgatccggc gatccattgg aatagctgta tcagtttgat
    21721 aatattcctt atttagccag ctgcctgtta ctacgtgcca gaaactaagc agaaagacac
    21781 ctatcgcaaa accatttgga atcaagagga ccaataaaga agaactcagt ccaagcaatt
    21841 gcatagccaa tggagaccat gttaaacgtt tcaaaatcca tggtccgact atttttgctg
    21901 caatcaagcc tgctgcataa ggcaaataca taaaaatcga aagtttttct aatccgtaca
    21961 gtatgccaac ataaaaactg ctaaataaaa aaaggaaatt ccctagcatt ccatttagaa
    22021 aagtaaacag atttagccag cttggcaact tccattcctt cttctggtgt cctaaaacaa
    22081 acacgaacaa gatgaacagc agcaagaaac cataaatagc aagatcaaaa agcctttcat
    22141 cgaataacaa tcgggcattt ctcaaaagaa acaataagcc aaagaatatc aaaaataaaa
    22201 caagctctcg cgtagctacc agatttcttt tgatgtcttt gaaatccagt tcgtaacgcg
    22261 gataatgact aaccgtatgg taggccatga cgtaaaaaag tgtataaata gtaaagcttg
    22321 ctgcaatctg agtcggtgca ggcaactcaa tcgcttgata caggagaaat agccagatag
    22381 ctgcaaataa gtactttttc ccatccatat tgataaaacc ttgcgtcttt tcgtgaaaat
    22441 tgaccgtggt attagcaggt acaagccatg ctgcactcag ccctagcaaa acacttgaaa
    22501 aataaaataa aggaaaataa aatacgccta atattccaag caatgaacca gcaccaccaa
    22561 tcagcagagc gatcatcagc aacgtgtaac tatctagacc aaatcgtaga ctgttgacta
    22621 aaaatagtcc agtcatccga aaggcataaa acagcgtaaa tggcaaaatc gtcagccaat
    22681 tatgcgagtc tgttagtccc aaaaataaaa gataaggaat aaaaataacc gtgttactta
    22741 agataaaggg cgttgtttgt gtaaaattac gcccaaatcg tttgagtttt tcgaacatga
    22801 caatggctcc ttaaacagtc ttataactaa tctgctcttc gattttagca ttaaagggga
    22861 aataaaccaa ttttacagaa tatattcttg taaaaaaaaa tacagaaaga agcataagct
    22921 tctttctgca tttttacggt acttgattac tcaagcagac aagcccttct ccacaaaagt
    22981 cttgcccgac acccctgcat ccggcaggtg ataaagatag aaatcaatta tcctgtgcct
    23041 ccaaaatcaa ttaggagctc tgtaaaccag agtccttctc gacccgtcgc ataaatttac
    23101 tttaacacag ttcctatgtt tatgcgagag cttttttcat tttataatcg accatttgaa
    23161 atccttgacc gatatctgaa ataagttctt ctgtaatctc aaatccttca tgcttataaa
    23221 cctcgattgc ttgatgattc ccctgattca ctcgcaaaaa gatctctctt tcctttgttt
    23281 gcgcagcaag ttcttcatac cagcgaaaaa ctgaagaagt caatccttga ccacgtactt
    23341 tatttagcaa atataattta cttaaataaa tttttccatt tatctcttca taagcagtgt
    23401 aaccgacagt cttttcttcg ctttttaata aaaagtagga cacaccttct gtcagttctt
    23461 tttgaatctg tttttttgac tgataagttt tcagcatgta atccacttgt ttttgaccaa
    23521 tgatcggcac aaaaacttcc ggccatactt cttgtatgac tgccatcagc tcatccagtt
    23581 cattttctgt tacttttatt ttttccatac acccacgtcc ttttttacat tataaatgac
    23641 cttgcgcttg atggaataaa aagagcatga tcatgctata cacacccacc gaccacggtt
    23701 tcaagaaaat cacaatctgc ataaattccc taaaagataa tttcgtcaaa ccagctacta
    23761 gacagatcaa gtcgtctggc gcaaagggaa gcagcaaggt aacaactagt acttttttaa
    23821 tatctttcgt ttttcttgtc agcaattcat caaatttctg atactttttt ggcgataaaa
    23881 taagctggac aaaggctacg ccatagtaac ggacaagcaa aaatccgatt gcttccccaa
    23941 tcactaggcc aatacaacta tataaaagcc caaatccatt gccaaacatc agcatgcccg
    24001 ctactgagga gatccctccc ggcaaaatag gaatgatcac ttggatcact tgcaacagaa
    24061 caaatatcat cactgcatac ttgccaaatt gctggataaa cgcttgcaaa gacgtgctcg
    24121 atcgaaaaat cccatgatga taagcataaa gaatcaacac aaagaaaaaa aacagaccaa
    24181 taatgggcat gatctgaaga catttttgta aaactgatcc ttttttagac atctatattc
    24241 cccacatctt ttttcattta ttaaaactgc ctccttatga actgaacccc aaaagttgaa
    24301 ctatttaatg gactgtttcc gatattctac tggagatagt ccatttaact ttagttttat
    24361 ccttttgtta ttataccacc taatatactc atttaattta ctttgaaata tctcaattga
    24421 tcggaatttt tctcgataaa aaaactctga tttaagcaca ccaaaaaaat tttctattac
    24481 agaattatct aagcaatttc cttttctaga catgctttga ataatgttat tctcttttaa
    24541 ttttttttga tattgtggca tctgatactg ccatccttga tctgaatgta gaatcagtga
    24601 accctcagtt cccttttttt taattgcttg ttgaagcatt tcttcaatca gtttatatgt
    24661 tggactagtt gatatactat aactaattat ttctccgtta aataaatcaa gtataggaga
    24721 tagatagatt tttcttcctt ttatcttgaa ttcagtgacg tctgtcaccc attttttatt
    24781 gggtgtatct actgaaaaat ttcgttttaa cacattcttg gcaatttttc ctactgttcc
    24841 tttataagat ttatatcgct ttattcggat ttgacaggta agtcccattt gggacattaa
    24901 ttttctaact gttttatgat tgattgtata tcctttcatc tttaacgcta aagtgactct
    24961 acgataacca taagagtttc ttgattcttt tacaatcgct gtaatttctt gctttatctt
    25021 gctatattta tctggcttat ctaatttttt tacccagtaa taataagttg acttcgctaa
    25081 ttgtgcaatt gaaagtaata gattcaattt aaattctttt ttgagctgaa ggattgtttt
    25141 aaccttgatt tcttcttgct caaatcttgt tcttgaatca aggtttct
//
LOCUS       DAZULR010000037        24725 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.037, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000037 DAZULR010000000
VERSION     DAZULR010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24725)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24725)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24725
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.037"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            8..81
                     /locus_tag="ACG8ZV_001842"
     tRNA            8..81
                     /locus_tag="ACG8ZV_001842"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:42..44,aa:Pro,seq:tgg)
     gene            101..173
                     /locus_tag="ACG8ZV_001843"
     tRNA            101..173
                     /locus_tag="ACG8ZV_001843"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:134..136,aa:Ala,seq:tgc)
     gene            201..274
                     /locus_tag="ACG8ZV_001844"
     tRNA            201..274
                     /locus_tag="ACG8ZV_001844"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:235..237,aa:Met,seq:cat)
     gene            288..361
                     /locus_tag="ACG8ZV_001845"
     tRNA            288..361
                     /locus_tag="ACG8ZV_001845"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:322..324,aa:Ile,seq:cat)
     gene            385..474
                     /locus_tag="ACG8ZV_001846"
     tRNA            385..474
                     /locus_tag="ACG8ZV_001846"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:421..423,aa:Ser,seq:tga)
     gene            487..560
                     /locus_tag="ACG8ZV_001847"
     tRNA            487..560
                     /locus_tag="ACG8ZV_001847"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:521..523,aa:Met,seq:cat)
     gene            579..654
                     /locus_tag="ACG8ZV_001848"
     tRNA            579..654
                     /locus_tag="ACG8ZV_001848"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:612..614,aa:Asp,seq:gtc)
     gene            656..726
                     /locus_tag="ACG8ZV_001849"
     tRNA            656..726
                     /locus_tag="ACG8ZV_001849"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:688..690,aa:Gly,seq:tcc)
     gene            740..813
                     /locus_tag="ACG8ZV_001850"
     tRNA            740..813
                     /locus_tag="ACG8ZV_001850"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:774..776,aa:Ile,seq:gat)
     gene            838..925
                     /locus_tag="ACG8ZV_001851"
     tRNA            838..925
                     /locus_tag="ACG8ZV_001851"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:872..874,aa:Ser,seq:gct)
     gene            947..1018
                     /locus_tag="ACG8ZV_001852"
     tRNA            947..1018
                     /locus_tag="ACG8ZV_001852"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:980..982,aa:Glu,seq:ttc)
     gene            1041..1130
                     /locus_tag="ACG8ZV_001853"
     tRNA            1041..1130
                     /locus_tag="ACG8ZV_001853"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1077..1079,aa:Ser,seq:tga)
     gene            1143..1216
                     /locus_tag="ACG8ZV_001854"
     tRNA            1143..1216
                     /locus_tag="ACG8ZV_001854"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1177..1179,aa:Met,seq:cat)
     gene            1235..1307
                     /locus_tag="ACG8ZV_001855"
     tRNA            1235..1307
                     /locus_tag="ACG8ZV_001855"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1268..1270,aa:Asp,seq:gtc)
     gene            1311..1383
                     /locus_tag="ACG8ZV_001856"
     tRNA            1311..1383
                     /locus_tag="ACG8ZV_001856"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1344..1346,aa:Phe,seq:gaa)
     gene            1388..1458
                     /locus_tag="ACG8ZV_001857"
     tRNA            1388..1458
                     /locus_tag="ACG8ZV_001857"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1420..1422,aa:Gly,seq:tcc)
     gene            1471..1544
                     /locus_tag="ACG8ZV_001858"
     tRNA            1471..1544
                     /locus_tag="ACG8ZV_001858"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1505..1507,aa:Ile,seq:gat)
     gene            1556..1627
                     /locus_tag="ACG8ZV_001859"
     tRNA            1556..1627
                     /locus_tag="ACG8ZV_001859"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1589..1591,aa:Glu,seq:ttc)
     regulatory      1816..1895
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SMK box riboswitch (SAM-III) riboswitch; SAM
                     riboswitches modulate the expression of downstream genes
                     in response to levels of S-adenosylmethionine; SMK box
                     riboswitch shares no known similarity to SAM-I and SAM-II;
                     Derived by automated computational analysis using gene
                     prediction method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            1893..3086
                     /gene="metK"
                     /locus_tag="ACG8ZV_001860"
     CDS             1893..3086
                     /gene="metK"
                     /locus_tag="ACG8ZV_001860"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HFS4997174.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            3216..4688
                     /locus_tag="ACG8ZV_001861"
     CDS             3216..4688
                     /locus_tag="ACG8ZV_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HFS4997175.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            4771..5559
                     /locus_tag="ACG8ZV_001862"
     CDS             4771..5559
                     /locus_tag="ACG8ZV_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFS4997176.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(5626..6294)
                     /locus_tag="ACG8ZV_001863"
     CDS             complement(5626..6294)
                     /locus_tag="ACG8ZV_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HFS4997177.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQIMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            6409..8121
                     /locus_tag="ACG8ZV_001864"
     CDS             6409..8121
                     /locus_tag="ACG8ZV_001864"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4997178.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            8124..9893
                     /locus_tag="ACG8ZV_001865"
     CDS             8124..9893
                     /locus_tag="ACG8ZV_001865"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010762530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4997179.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENCKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFE"
     gene            complement(10098..10664)
                     /locus_tag="ACG8ZV_001866"
     CDS             complement(10098..10664)
                     /locus_tag="ACG8ZV_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFS4997180.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(10664..11620)
                     /locus_tag="ACG8ZV_001867"
     CDS             complement(10664..11620)
                     /locus_tag="ACG8ZV_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HFS4997181.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(11620..12276)
                     /locus_tag="ACG8ZV_001868"
     CDS             complement(11620..12276)
                     /locus_tag="ACG8ZV_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HFS4997182.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKIRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            12646..14664
                     /locus_tag="ACG8ZV_001869"
     CDS             12646..14664
                     /locus_tag="ACG8ZV_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFS4997183.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    14734..14940
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15091..17505
                     /gene="leuS"
                     /locus_tag="ACG8ZV_001870"
     CDS             15091..17505
                     /gene="leuS"
                     /locus_tag="ACG8ZV_001870"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HFS4997184.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            17853..19406
                     /locus_tag="ACG8ZV_001871"
     CDS             17853..19406
                     /locus_tag="ACG8ZV_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WD40/YVTN/BNR-like repeat-containing protein"
                     /protein_id="HFS4997185.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(19787..21571)
                     /locus_tag="ACG8ZV_001872"
     CDS             complement(19787..21571)
                     /locus_tag="ACG8ZV_001872"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4997186.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNFAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(21586..23307)
                     /locus_tag="ACG8ZV_001873"
     CDS             complement(21586..23307)
                     /locus_tag="ACG8ZV_001873"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4997187.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLQIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            23407..24168
                     /locus_tag="ACG8ZV_001874"
     CDS             23407..24168
                     /locus_tag="ACG8ZV_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFS4997188.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IRERKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
BASE COUNT         7710 a         4506 c         5207 g         7302 t
ORIGIN      
        1 aattaaacgg gaagtagctc agcttggtag agcacttggt ttgggaccaa ggggtcgcag
       61 gttcgaatcc tgtcttcccg ataattataa atttaaacac ggggccttag ctcagctggg
      121 agagcgcctg ctttgcacgc aggaggtcag cggttcgatc ccgctaggct ccatttcatt
      181 taaataatga atatcttttt cgcggtgtag ctcagctggc tagagcgtcc ggttcatacc
      241 cgggaggtcg ggggttcgat cccctccgcc gcgattttta agagcctgga cctttagctc
      301 agttggttag agcagacggc tcataaccgt ccggtcgtag gttcgagtcc tacaaggtcc
      361 attgtggcgt tgtaagtttc atatggagga ttacccaagt ccggctgaag ggaacggtct
      421 tgaaaaccgt caggcgggta aaaccgtgca agggttcgaa tcccttatcc tcctttttca
      481 tattatcgcg ggatggagca gtctggtagc tcgtcgggct cataacccga aggtcgtagg
      541 ttcaaatcct gctcccgcaa ttaaaaacta aaaacactgg ttccgtggtg taggggttaa
      601 catgcctgcc tgtcacgcag gagatcgcgg gttcgattcc cgtcggaacc gccatgcggg
      661 tgtagtttag tggtaaaacc acagccttcc aagctgttgt cgcgagttcg attctcgtca
      721 cccgctttta gttttttatg ggcctatagc tcagctggtt agagcgcacg cctgataagc
      781 gtgaggtcga tggttcgagt ccatttaggc ccattagtac aaaatcttat tggttttggg
      841 gaagtactca agtggctgaa gaggcgcccc tgctaagggt gtaggtcggg aaaccggcgc
      901 gagggttcaa atccctcctt ctccgtttca atattttgtt ttacctggcc cgttggtcaa
      961 gcggttaaga caccgccctt tcacggcggt aacacgggtt cgaatcccgt acgggtcatt
     1021 aatttaatat agttttacat ggaggattac ccaagtccgg ctgaagggaa cggtcttgaa
     1081 aaccgtcagg cgggtaaaac cgtgcaaggg ttcgaatccc ttatcctcct ttttcatatt
     1141 atcgcgggat ggagcagtct ggtagctcgt cgggctcata acccgaaggt cgtaggttca
     1201 aatcctgctc ccgcaattaa aaactaaaaa cattggttcc gtggtgtagg ggttaacatg
     1261 cctgcctgtc acgcaggaga tcgcgggttc gattcccgtc ggaaccgttt ggctcggtag
     1321 ctcagttggt agagcaatgg attgaagctc catgtgtcgg cagttcgatt ctgtcccgcg
     1381 ccattatgcg ggtgtagttt agtggtaaaa ccacagcctt ccaagctgtt gtcgcgagtt
     1441 cgattctcgt cacccgcttt tagtttttat gggcctatag ctcagctggt tagagcgcac
     1501 gcctgataag cgtgaggtcg atggttcgag tccatttagg cccatttatt ttattggccc
     1561 gttggtcaag cggttaagac accgcccttt cacggcggta acacgggttc gaatcccgta
     1621 cgggtcatgg aagatacttt ttgagtatct ttttcttttt atctgaaaga atgattttaa
     1681 aaagcttagc agagttatct ttatggatga ttgtgctaag cttttttgga cagttctaat
     1741 gtaaaatatt tttatatttt ttaagcaaaa aaatgaaaaa atacgagcag aaaactgttt
     1801 tatctgctat acttggttcg ttgcaagttc ccgaaaggat ccgcaggacg gagatgcctt
     1861 gtaaccgaat ttaactaggg ggaatcatta taatggtaga aagacactta tttacatcag
     1921 aatctgtttc tgaaggacat ccagataaaa ttgctgacca aatcagtgat gcaatcttgg
     1981 atgcaatttt aaaacaagat ccaacagcac gagtagcgtg tgaaacgtct gtaacaactg
     2041 gtcttgtttt agtatttgga gaaatatcta cgacggcata tgtagatatt caaaaagtcg
     2101 tacgggaaac aataaaagaa attggttata cacgtgcaaa attcggattt gatggagata
     2161 cagcagctgt attggttgcg attgatgaac aatctcctga tattgctcaa ggagttgatg
     2221 aagcacttga gatccgggat gaagataaaa aagacgtatt agatgagatt ggtgctggtg
     2281 accaaggttt aatgtttggg tttgctgtag atgaaacacc agaattgatg cctttaccaa
     2341 tcgctttgag tcatcgtctg gtacgacgct tggcagattt gcgtaaatca aatgaattaa
     2401 cgtatttacg tccagatgca aaatctcaag taacggttga atatgatgat caaggacaac
     2461 cggaacgcgt agatacaatc gttatttcaa cacagcatga tgatgcagta gataatgaaa
     2521 caattcgtca tgatgtcatc gaaaaagtag tgaaggaagt tattccagct gaattattag
     2581 atgatcaaac gaaatattat atcaatccga ctggccgatt tgtcattggt ggtcctcaag
     2641 gggatgccgg attaacagga agaaaaatca ttgttgatac gtatggcggt tatgctcgtc
     2701 atggtggcgg tgctttttct ggtaaagatg cgacaaaagt tgaccgttct gccagctatg
     2761 ctgcacgtta tattgctaaa aacattgttg cagcagggct tgctcgcaaa gcagaagtac
     2821 agctagctta tgcgattggt gttgctcaac ctgtttcgat ctcaatcaat actttcggta
     2881 ctggaacggt tccggaagaa gaactgattg ctgcagtgag agaaaacttc gatcttcggc
     2941 cagcaggaat catcgagatg cttgatttgc gtcgtccgat ttacaaacaa acagctgctt
     3001 acggtcattt tggtcgtaca gatgtagatt tgccttggga acatacggac aaagtagatg
     3061 cgttgaaagc aagtttagca aaataagtta tattcagctg gaacgatcgc caagtggtgg
     3121 ttgttccagc tttttttatg gcagttaacc tcttgaaaaa gatagtaatt atttatctat
     3181 ttttagatcc tgtcataatg aaagggagga ataagatgaa aaaagaaaca aatgttactt
     3241 tggtcacagt gagtattttc attgcaacgt tcatgacggc tattgaaggt acaatcgtaa
     3301 caaccgctat gccaacgatt gtcggttcat tacatggaat ggaaatcatg aactgggtat
     3361 tttcgattta tttgctgaca aacgctatgc ttactccgat ttacggaaaa cttgcggata
     3421 aagtgggacg gaaaccaatc tttatttttg ggacattatt gtttattatc ggttcgttat
     3481 tttgcggttt atctcaaagc atgattgggt tgattgctgc tcgtgcgatt caagggatgg
     3541 gtgctggggc aatgatgcca gtagctttga cgatcatcgg cgatctttat tctattgaaa
     3601 agcgagcaaa agttttaggt ttgaatagtt cagcctgggg gattgccagt gtttttggac
     3661 cgcttgcggg aggattcatc gttgaaacga tcagctggca ctggatcttt tttatcaatg
     3721 tgccgatcgg aattctatta attattttga tttggctata tttaaatgaa ccaaaaatca
     3781 tacatgagtc taaaccaatg gatatttttg gtagttttag tttgatggcc atgcttgtct
     3841 cattgctgtt agggttccaa ttattaggag acgaaggaat gagtccgctt gtttctgctt
     3901 tgctgctagg tagtatcgta atgttaggta tttttgtttt tgccgaaaaa agagctaaag
     3961 atcctgtcat catgatgcat ttattcaaaa atccactatt tgttgtggtc aacttggctg
     4021 cagcattggc tagtggtttt ttgatgggaa tcgatgttta tatccctatg tggatgcaag
     4081 gtgtattagg gctgaatgca gcaattggtg ggctggtatt agcaccatta tcactagtct
     4141 ggatggtcgg ttctttcctt gcaagcaagt ggatgactca aatgaaaact cattgggtct
     4201 tgagaattgg actactaatc gcagctattg ggggcgcttg gttgtatctt atgcctttca
     4261 gaagtaacta tttatggttt tttgctatat caacggtcat cggtataggc ttaggtgtga
     4321 ccatgactac ctcgactgtc agtgcacaaa atagtgtatc tcgtgaccag cttggtgtag
     4381 caacttcttt taatacgtta gttcgaacaa ttggtcaaac agtcatggtt tctatttttg
     4441 gtttattgat aaatggggta actaaacgag aacttgcagc agcaaattta acaaatgatg
     4501 cagatatcat gaataaactg gtgaatccac aaacggctaa atatattgat gcggatattt
     4561 tgttaccatt aagaaaaatt ctttatgatg ggttacattc cgtttatcta gttggcttgt
     4621 tactcgtgat cattgctttg gtcttaacgc ttttcgttca tgaaaaaagt ggtaaaataa
     4681 aacagtagtt tcggttaaga tatgtacgta gccgaatcat tcaaatttaa agttattcaa
     4741 aaataacttc ttactaagga aggcgaaaat atggcattta ttcaagcaaa tatttattcg
     4801 aatgtgttag aaatggaagt caatctaaat gtgatactac cgcaaacaac aaaaaaggtg
     4861 attggcacca gttcagagca agagacaacg gatatacctg ttttatattt acttcatgga
     4921 atgggtggca atcatagtgt atgggaaaga cgtacgtcga ttgaacgtta tgtagcaaac
     4981 tacggattag ctgtcatcat gccatctact gatcttggct ggtacacaga tacagtttat
     5041 gacatgaagt attggacatt cattgcagaa gagctacctg agatttgtca tgaattattc
     5101 ccgcaattaa caagaaaaag agaaaaaaca tatgccgctg gattatcgat gggcggatat
     5161 ggcgcgttaa aactaggcct tgcaaaatca gaaaatttcg cagcagtaat ctctctttca
     5221 ggcgctgttt ctgtaggaaa tcgaatggat gatcttttga tggttcgtaa agcatctttt
     5281 tgggaaggga tctttggacc attggatcaa atcgaaggtt caaaaaatga tccgcaatac
     5341 ttattgaaag aactagtaaa aagcggaaaa ccagttccaa gattttatat ggcttgtggg
     5401 gaatctgatt ttctttatca ggcaaatcag gaaatggtat ctgctatgca ggaacaaggc
     5461 ttggcggtca cctttgaaca aggacctggc gatcataact ggatcttctg ggaccaatgg
     5521 attcaacgtg cattggcgtg gctaatggaa gaaaaataaa aaaagagtct taaaaagata
     5581 gctcctatag agatcacaaa catagtgatc tctataggag cttttttact gctcgttttc
     5641 tcttctttta ttttgttggc ataagccttc aatataggtt tgtgcactcg ttagaaagag
     5701 tgctttttca ttcaattctg catgggactg catactttct ttaaatccct ctaattgatt
     5761 ttcaactaca taattacgca taaatagaac tgtttctttc aaaaattcat ttccgtccat
     5821 aattttttgt cgaagctgct gttcatgctg ctgatccatt aactgtccaa tcaataaatt
     5881 gtggagagag gcaatggcct gatgactttg ggtgactgaa aatccttcac gaacaagtaa
     5941 ttggatcatt tgctccaaat gttctaatcg actcggaaaa gcgggcacag tattgatttc
     6001 taattctgcc ccacaaggga aacgtgtata aaggtcatag taattttcca tatactgcag
     6061 caactgttca ttccaaggca aagttggatc tggaagcgct aattcttctt ccattgtttc
     6121 agccattatt tgcaagagct gttgtttgtt tttgaaatac caatataaag caggtgcttg
     6181 aacatgaatt ctgtttgcga tgtttcgcat ggaaagctgc gaaagagctt gtgtttcagc
     6241 caggatatca aaggcggcct gaatgatgat tgcttgagaa agctttattt ccattttatc
     6301 aacctcgtgt attgcattat ctttttaaac atggtaaatt gttagtcggt ctaattttac
     6361 agtgttaaat tagtcctgtc aatttaaaca aaggggtgta atcaacgaat gaaattaatc
     6421 ttacgacatg cgaaaaaata taaagtagct gtttttattt ccttgctgtc cgtagcagtc
     6481 atggttgcag cagcattatg gcaacctaag ttactacagc aagtattgga agctattatt
     6541 acagaagata atgatgaaat gaaaacaatt ggtatttacc tgatcagtct ggctttgcta
     6601 ggattagccg caggtgtaac gaacacgatt ttctctgcaa aagtagctca aggcgtaagt
     6661 gcagatatcc gagaagaagc atttcgaaag atccagacat tttcatttgg aaatatcgaa
     6721 cagttctctg ctggaaatct tgttgttcgt ctaacaaatg atatcacgca aatccaaaat
     6781 ttagtgatga tttctttgca atcacttttt cgaattccat tcttatttat tggtgccttc
     6841 attttagcta tgatcacgat gccgcaatta tggtggatca tcgtagcgct tatcgttacg
     6901 gtatttctga ttacggcact ttcatttaca aggatgggca agcacttcat gatcattcaa
     6961 aaactgattg atcgtgtgaa tagcattgca aaagaaaact tactagggat tcgtgtagtg
     7021 aaatcttttg tacaagaaga aaaccaattg aagtcattca gcaaagtaag tgaggactta
     7081 acaaaacaca acatcatagt cggtacatta ttttctgtga tgatcccgtc cttcatgctg
     7141 gctgccaatt tggctgtggt tggggcgatc ttttttgtga gcgatcttgt taaagatgat
     7201 cctacgttaa ttggtggaat tgcttcattc atgaactact tgatgcagat tatgatggca
     7261 atcattattg gcggaatgat gatgatgatg acttcaagag cagccgtatc gctgaagcgg
     7321 attgcggaaa ttttagatgc tgaaccagat cttacttatt tagacgttcc agaacaagag
     7381 ttgacgggtt ctgtcacttt tgaccatgtt tcttttcgtt atcctggtga ggatacagat
     7441 acgcttaaag atatcagctt ttctatcaaa cctggagaaa tggttggtat cgtcggggcg
     7501 actggtgccg ggaagtcaac actagcacaa ttgatccctc gtctatttga tccgacagaa
     7561 ggcaaagttg aagtaggtgg tgtagatctt cgtcaagtaa atgaaaagag tttaagacaa
     7621 acggtttcct ttgttttgca aaaagcaatt ttattctcag gaacgattgc tcaaaacttg
     7681 cgccaaggga aaaagaatgc aacagaaaaa gagatggaac atgcttcttc tattgctcaa
     7741 gcaaaagaat tcatcgaaaa gttatctgat cgttacgaag caccaataga agaacgtagc
     7801 agtaactttt ctggtggtca aaagcaacgt ttatccatta ctcgtggcgt tatcggtaat
     7861 ccaaagatct tgatcctaga tgacagtacg agtgcactgg atgctcgctc tgaaaagctg
     7921 gtccgagaag cactcgatcg agatttgaag ggaacaacga cgattgtcat cgcacaaaaa
     7981 attgcttctg ttgtcaaagc agaccgcatc ttagtattgg atgaaggcag attagtcggc
     8041 gaaggaaccc atgaggaatt ggtagctgga aaccgtgtct atcaggaaat ctttgaaact
     8101 caaaaaggaa cggaggagta agtatgactg atctaataaa agcaagtaaa tttttctatc
     8161 actatttgaa gcggtacaaa ctctcctttt tctttatctt tatcacagtg atcattgcta
     8221 cctatctaca agtaaaggca cctcaataca tcggggaagc ttttcaagaa ttagctaatt
     8281 acgtaggagg cttgatgcaa ggcgtagacg ataaaagcaa atttgtttct gtaatatgga
     8341 aactcttgct gttttatgta ctagctagtg cagccaactt tatctatagt attttgttca
     8401 cacaagtagt agggaagtca acgaaccgaa tgcgtatcgg tctattcaac aaattggaaa
     8461 aattgacgat ccgtttcttt gattctcatc aagacggtga aattttaagt cgttttacca
     8521 gtgacttaga taatattcaa aatagtttga accaagcttt gcttcaagtc atcacgaatg
     8581 ctgttttact tgtcgggatc ttgatcatga tgttccgcca aaatgtagag ttagcttggg
     8641 ctacaattgc ttccactcca gtagccgttt tgatagctgt cttgattatc cgcaaagcac
     8701 ggaaatatgt ggatcttcag caagatgaag tggggaaact aaatggttat atggatgaaa
     8761 aaatcagcgg acaacgtgtc atcatcacaa atggcttaca agaagaaacg attgaaggat
     8821 tcttagagca taatcaaagt gttcgcgaag caaccttcaa aggacaagct tattctggtc
     8881 tactatttcc gatgatgcaa ggaatgtcac tggtcaatac agcgatagtt atctttttcg
     8941 gcggctggtt agcattaaat ggtgatttgg aacgttcggt ggcattaggc ttagttgtga
     9001 cattcgtcca gtattcacaa caatattacc aaccactgat gcagatttca tctggataca
     9061 gcatgatcca attagcgatt acaggggcaa gacgattgaa tgaaatattt gatgaaaaag
     9121 atgaagtcaa accagaaaac tgtaaagcat ttgatggtgt tgaaaaaggt cttgcgttgc
     9181 agcacgtaga ttttggttat tctccagaaa aactagtctt gaaagatgtc tcgatcaatg
     9241 tggacaaagg agaaatggtt gctcttgttg gtccaacagg atcggggaaa acgacgatca
     9301 tgaatctgct aaaccgtttt tacgatgtca atgatggttc agtagtcatc gatggaatag
     9361 atatccgaga ttatgatctt gatgcattac gtagacatgt aggaatcgtt ttgcaagaat
     9421 ctgtattgtt ctccggaacg atcaaagaca atatcacatt cggcaaaccg gacgcttcag
     9481 atgaagaagt catcaatgca gcaaaacaag cgaatattca tgacttcatc atgacgttag
     9541 aaaaaggtta tgatacagag atatccgaag aaaataactt attcagtaca ggtcaaaagc
     9601 agttgatcag tattgctcga acgatcatca caaatccatc tttattgatt ttggatgaag
     9661 caacaagtaa tgtagacacg gtaacagaag caaggatcca aaaagcaatg gatgaagcaa
     9721 tcaaaggaag aaccagcttt gtgattgctc accggctgaa aacaatcttg aatgcagata
     9781 gaatcgttgt cttgcgtgat ggggaagtca ttgaagaagg cagtcatcac gagttattag
     9841 cagaaaatgg attttatgcg gaactttatc ataatcaatt tgtatttgaa taaagaggtt
     9901 gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa tcaaaaacag cttctcatgt
     9961 ttttgatttg gttggactta ttaccgcaga tataagcttt tgagcaccgt gaataaagag
    10021 gttatgaaat caacgctcta acctgagtat tagagaaaaa aacgcaaaac atatcattta
    10081 tgttttgcgt tttttattta tctttttttc tcaatacaat ataaaatagg cggctggttc
    10141 ttttggttga taaaccgata attcagcaca ttatatgttt cctgtggcag tttggaacaa
    10201 aaagaatcaa ccatatccag ttctttttct ccaccttcat gaccatagta gacgacaagg
    10261 atcaatcgtc cgcgaggcac aagtcgtttc aatatttctt ccatagctgt gcgtgtagtc
    10321 tctggcatag tgatgattgc tttatcactt tttgggagat accctagatt gaaaatccct
    10381 gctttgagat tttgttgttc agctatcact tctcctaacg tttcgtggcc ttgtagaaac
    10441 aatgagacac gttcttctaa ctgacgctgt tctagccttt cacgagtagc atcgattgct
    10501 tgttgctgga tatcaaaact atagacatga ccagtttttc cgatgtgttc tgctagaaaa
    10561 accgtatcgt ggccattgcc catcgttgca tctacgacgt gatcccctgg ttgcaagatt
    10621 tcttgcagta atgtatggct gaaatgcaaa gcagtttgca acatcagacg ctcacctttt
    10681 tccgtacatc atattttcct tggaagctat ctctgcgaag aagttcttca tcaattgcat
    10741 tcaagacttc ccattttttc aagctccaca ttggtccaat caaggaatcc cacggcgcat
    10801 cccctgtcaa acgatggatg atgatctctt ttggtatcat ttccagctgg tcgcaaatga
    10861 cattgacata gtcaggacgg ctcattaatt gaaggcgacc ttcatgatag tcccgcaaca
    10921 ttctcgtttt gcgcatcaga tgcatcaaat ggagcttgat tccttggata tctgaatcta
    10981 aaatggtgcg tctgacattt tctttcatca tttctaaact ttcgcctggt aatccgttga
    11041 tcaaatgcgt acaaacacgg atattatgtt tgcgtaattt agccacgcca tctaaataag
    11101 tttgataatc atgtgctcgg ttgatcagtt ttgaagtttc ttcaaaagtt gtttgcaatc
    11161 caagttctac ccataaatac atccgctcgt tcagttcagc aaggtaatca actacttcat
    11221 ctggcagaca atccggtcgt gtaccgactg ataatcctac gacacctggt aaattgacta
    11281 cttgctcaaa tcgttctttg attatttcaa ctggcgcatg ggtgtttgta aaattttgga
    11341 aataaacgat gtattgttgg acatgaggcc atttttgatg catcatgtcg atttctttct
    11401 ggaattggat tggaagaggg tcttcaggtg caacgatcat gtctcccgaa ccagatacac
    11461 tgcaaaaagt acaaccgcca tgggcaacag tcccatctcg attcggacag tcaaatcctc
    11521 catcgatcgg caccttgaaa attttcccgc caaactcatt tcgtaaagcg taattccaag
    11581 aatgatatct tttatttcct tctgaataag gaaaagtcat taaaagtcct tctttctgta
    11641 agagttatct atttgttttc ttttttctct atacactgga taagtcaggc acagccaaga
    11701 aagactgagt aagtaaccgc cgatgatatc agtaggaaaa tgaacgccca gataaatgcg
    11761 gcttatcccg acacttacta taataaacat catcagcaat tgaagcaatg tgcgtaaggt
    11821 tcttttttga acaaaagctg gaagcagaaa tagtaaagaa ccgtaaagaa tcatactgcc
    11881 tgctgcatgt ccactaggga aactgtaact tgtttcaact actaagtgcg ccaatgaagg
    11941 acgctctcgc atgaaaaata gtttgatcac cgggttgatg attccagcaa ttacaataaa
    12001 tccagaaacg aaccaaaatg tttctgccct tattttctta taccacatcc ataaagccgc
    12061 acaagcaaat aaaatgatga cggtaagagg attaccgaat ttagtcataa agagttggta
    12121 gctgttcaga tcaggataag aagctctgac aatgcctgta aaccactgat cgaaaccaga
    12181 aagccacgac agatggaact ttacgatcca gcccaaaatg aaaaacagga caagaaagaa
    12241 gctaccagcc acctgaaatg atgttttata tttcatacaa ttcctccttt gaagcaatga
    12301 cttattatag catttttggt ccagcgaaaa aaacggtaaa gagataaaac caatgtatga
    12361 ttcctctttg aataaccaat attcttataa aaaaaataac tgtaatcgga aagacatttt
    12421 ttggtaatgc aaatgaaatg ttagggaaat aaaatcagtg tttttcgaaa tccttttaaa
    12481 caagaacgta gacgtaggaa gaacttgaaa atgaacagaa gttgttcatt acggtaaatt
    12541 acaatatgat tacaaaaaac aacaaagctc ttaaataact tttaataaat attaagagaa
    12601 gttataatta ttaataatag ataaattgaa gttggaggat agaagatgga aaacattgca
    12661 agaaaagaac ggagacgttt agaacagacc aaacgttttc gaaaagcaaa acgaggggca
    12721 gcaatcgtgg gaactgcgat ggtaggctgt tctgtcgctg ccccattagt acagccggtt
    12781 cctgttcaag cggatgaaac acctgttcag ttcggcgcaa gaatcaatac agcggcattt
    12841 atcacagaaa ttgctactta tgctcaacca atcgctcaag ccaacgatct atatgcatca
    12901 gtgatgatcg cacaagcagt tgtagaaagc ggttggggca gtagtgcgtt atctcaagca
    12961 ccttattata atctttttgg gataaaaggc agctatcaag gacaaaccgt ctacatggat
    13021 acgcttgaat ttttaaataa tcaatgggta aataaaaagg agcctttccg acaatatcct
    13081 tcttttgctg aatctttcaa tgacaatgcc tatgtactta gaaatacttc atttggcaac
    13141 ggttattact atgccggtac ttggaagagc aacacgaaat cctatacaga tgcgacagct
    13201 tgtttgacag ggcgttatgc gactgatcct ggttacgcag gcaaattaaa taatatcatc
    13261 gcaacttacg gattgaccca atatgataca ccagctagcg gaaacgcagg cggtggagcg
    13321 actacaggtg gcaataatac tggaagtgca ggtagtactg gcggttcaag caattctggt
    13381 aatacaaact caggttcagc aacttcgacc acttatactg tccaatctgg tgattctgtt
    13441 tggggaatct caaataaatt cggtatcaca atggatcaat tgatccaatg gaacaacatc
    13501 caaaacaatt tcatttatcc aggacaaaaa ctgacaatca aaggtagcca ggaaaatggc
    13561 tcttcgacga ataattccgg taacaatacc aattcttcag gaaatgctgg tacatcaaac
    13621 ggaggacaaa caactggtgc gaaatacact gttcaatctg gtgattctgt ttggaagatc
    13681 tcaaatgatc acggaattac gatggctcaa ttgattgaat ggaacaatat caagaacaat
    13741 ttcgtttatc caggacaaca gctaatcgta tcaaatggcg gttcttctaa tgctggagca
    13801 aatactggct caaatactgg gaatacaagt ggctctagtt cgtccagctc aagttcttct
    13861 aatacagctt caggaacgaa atatacagtt aaagccggag actctgtttg gagcgtctca
    13921 aataaatacg gaattacgat ggctcagcta atccaatgga acaatatcca aaataacttt
    13981 atctacccag gacaacaact gactgtttca aacagtggat caacaaacag cacgtcaggt
    14041 aatacaggtt cgtcaaccaa tacaaataac agcagttcag ttaatactgg cagcagttcg
    14101 tctcaaggca cttataccgt gaaagcaggt gaatctgttt ggagcgtggc aaataaaaac
    14161 ggcatcacga tggatcagtt aatcgaatgg aataatatca aaaacaactt catttatcca
    14221 ggacagcaat tgatcgttaa aggtggaact tcggcaaata caaatacagg ttcaactact
    14281 tctgcagcga aaccaaatac accgaatacg tctgctacga caagtacatc atccactggt
    14341 aatacgatgt ataccgtgaa agcgggcgag tcagtttgga gcgtagcgaa caaacatcat
    14401 atcacgatgg atcagttaat cgaatggaat aatatcaaaa ataatttcat ctatccagga
    14461 cagcaagtga ttgtgaagaa aggttcatct caatcaacaa accaacaatc agttactggt
    14521 tcgaaaacct atactgtgaa atctggagaa tctgtttgga gtgttgctga cagtcatgga
    14581 attacaatgg ctcaactaat cgaatggaac aatattaaga acaactttat ttatccaggt
    14641 caaacgttga ttgtagctaa ataaaatagc tgttcgaaga aataacgatt gaattccaca
    14701 aaaatatttg ttactataag gctacttaaa tatgacaaca cttgaaaagg aagtagtaaa
    14761 aagactgaag tttcagagag cgcatggctg gtgagaatgt gcacggatgc ttttgaactc
    14821 gcctttgagt tgcccttgct gaatacccga gtaagcaagc ggcggtgacg gccgttacaa
    14881 cgttcgaggc cttttcacta aggtaaaatt aggtggtacc gcgtagatta cgtcctataa
    14941 aaagagcaat ctttttatag gattttttta tttcttttgt gaagtttgag aaaacaaagc
    15001 aaaaggaaat aaaaataaac agattctgcc ggttttttcg ttatatttat aatagaaaca
    15061 agtgttttca atagaacagg aggacagcaa atgagttaca atcataaaga aattgagaaa
    15121 aaatggcaaa aatactgggc aaaaacgaat actttcaaca cccatgatga tcctgaaaag
    15181 ccaaaatttt acgcactgga tatgtttccc tatccatccg gtcaagggct acatgtaggg
    15241 catcctgaag gttatacggc aacggatatc ctttcacgtg tgaaaagaag tcaaggatac
    15301 aacgtgctgc atccaatggg gtgggatgca ttcggtctgc ctgctgaaca atatgcgcta
    15361 gatacaggaa acgatccagc tgagtttacc caaaaaaata tcgaaacatt ccgacgccaa
    15421 atcaattctt taggatttag ttatgactgg aatcgcgaag tgaatacaac tgatccggag
    15481 tattataaat ggacacaatg gatctttacg aagctttatg aaaaaggtct agcttatgaa
    15541 gcagaagtag cggtaaactg ggtacctgaa ttaggaacag ttatttcaaa tgaagaagtg
    15601 atcgatggga aaagtgaacg tggtggctat gatgtagtca gaaaaccaat gcgccaatgg
    15661 atgctgaaaa tcactgctta tgctgatcgc ttattggatg atctagaatt agttgattgg
    15721 ccagaaagca ttaaagaaat gcaaagaaat tggatcggtc gttcagtagg agcaaatatt
    15781 gaatttaaag tggctggtac ggataaatcc tataccgtat ttacgacacg accagatact
    15841 ctattcggtg caacttactc ggttcttgca cctgaactag atcttgttag agaaattacg
    15901 acccctgaac aaaaagctgc tgtagaagct tatatcgaag agacagctaa aaaatcagat
    15961 ctaaagagaa cggatcttgc aaaagaaaaa acaggagtat ttactggtgc ttatgcaatc
    16021 aatccagtta atggcaagga aatcccaatc tggatcgccg attatgtatt atcttcatac
    16081 ggcacaggag ccatcatggc tgttccagca catgatgaac gtgactttga attcgctcaa
    16141 actttcggac tagaaattct tccagttatc gaaggtggag atgttgaaaa agctgcttac
    16201 acagaagatg gtacgcacat caactctgaa tttctagacg gcatgaacaa acaagaagca
    16261 atcgataaaa tgaatgaatg gctagaagaa aatggcgtag ggaaaaaaga agtcagctat
    16321 cgcttacgtg actggctatt ctcccgtcaa cgttactggg gtgaaccaat cccaatcatc
    16381 cattgggagg acggaacagt cacagctgtc ccagaagaag agctaccatt acggttgcct
    16441 aagacaaaaa acatcaagcc aagcggtact ggagaatctc cattagcaaa tatcgaggag
    16501 tgggtcaatg tcgttgatcc tgtaacaggt aaaaaaggcc gtcgcgaaac gaatacaatg
    16561 ccacaatggg caggaagctc atggtattac ctgcgttata tcgaccctca taacaaaaaa
    16621 gaactagcag attatgaaaa gttgaagcgt tggctaccag ttgacatcta cattggtgga
    16681 gcagaacatg cggtacttca tttactatat gcacgattct ggcataaatt cttatacgat
    16741 atcggtgttg ttcctacaaa agaaccattc caaaaactat acaatcaagg aatgatctta
    16801 ggcgaaaaca acgaaaaaat gtcaaaatct cgtggtaatg tagtcaatcc tgatgatgtg
    16861 gtcgaaactt acggtgcaga tacactgcgc atgtacgaaa tgttcatggg gccattagat
    16921 gcttcgattg cttggagcga aaatggctta gaaggaagcc gtaaattctt ggatcgtgta
    16981 tggcgtttga tcgttgatga gaacaataaa atgcgtgacc gtatcactac attgaatgat
    17041 ggcaagcttg ataaagtgta tcatcaaaca gtgaaaaaag tgacagaaga ctatgaaaat
    17101 cttcatttca atacagcaat ctcccaattg atggtcttta tcaatgaagc ctataaagtg
    17161 gacgctctgc cttatgaata tatcgaagga tttgttcaac tactcgcacc gattgctcct
    17221 cacatgggtg aagaactatg ggcaatcctt ggaaatgatg gtggtatttc ttacgcacca
    17281 tggccaacat acgatgaagc agcacttgtt gaagacgaag tagaagttgt tttccaagta
    17341 aacggtaaag ttcgtgcgaa aagcaatgtt ccccgagact taggaaaaga tgagctagaa
    17401 aaagcagcat tagccaatga aatagtgcaa gaatatattg aaggcaaaac agtcagaaaa
    17461 gttattgcgg taccaaacaa gttagtcaat atcgttgcta attaattggc tctttgtcaa
    17521 taaggactga tgagttgtgc aaaatcaaat ctgggccaga atgaacttca ttctgtctca
    17581 gattttttgt tatttcaaat tgattaattg attgatcaaa aaggttttga ttttcatgtt
    17641 ctcaaacacg ttcaatgtct ttttcttctg aatggtcttg taagagatct ctgtaatcat
    17701 caaatttttg tctattaatc ttagtatttt ttgatgtata aactacctga aattgagagt
    17761 acataccaaa ttcataaatt ttttattagt gggactagtg attgtatgga ttttgacgca
    17821 taatgaatga agtatgagaa aaggagagac aaatggatca agaactattt attatcgaag
    17881 tattatcagc taaacaaaaa attatcgaga aagcgaaaaa aagagcgaaa agaataatgt
    17941 tcaagctttt aagcttagta tttttctctg gtttgctttt tttcggagct gtatcgttcc
    18001 tatatcgcca tatgagtgca gtagtccgtt cagctgaagg gatgcaaaaa ttaaataatt
    18061 tgtatcactt ttcgtgggga gttggcggaa taacaattgt tgtgcttatt gtttttcttc
    18121 tacttatttg gctccgttac catcaattgt cgcgtcattt cgatcaatgg cttagtcaaa
    18181 gagcacaaca gtttttacat aataaaccaa cttctcaaga tgatgactat ctttattttg
    18241 agaagacttc gacgagtcaa gcttttcgga tacaaaaaag tgattgccag ttattgctga
    18301 gatcacttga tgatttacct atctacttag gcgaaagcaa atcaaaattc ggaatgaaca
    18361 cattccatat ttttttacta gaaaacgaac ccagatggga aaaaagccag tcttcgcctg
    18421 gtggatacct gacaactaag atgagtacat tagtcactgg ttttttcctc attcttttag
    18481 ctggaacaat ctattatggg agatacactc agccaaaaat gtcttctcat ataaatgctg
    18541 cttctcacat gacaatgaac tcaactaacg atacgcatat acaaaagaca aatgaagggt
    18601 tgttagctga tcctaagcaa aaggtaaatt tgacaacaca aaagataaat gatctcaaac
    18661 ttgatacaga gacgcactct ctctatatga caacagatag tggtgctaat tgggtatttg
    18721 tgccgattga ttcgcaatgg ttgcgttttg gcgaatacac cctgacaacg gggctgattc
    18781 ctgaaggtta ttggatggac aacacatatg atatttccgc cgatttctca tggtttatct
    18841 attcttctgg ggatgatgta cgtctgctga cttcaagaga taatggtaaa acatggcaaa
    18901 cgtctattat cacccaatca gttcagccga tacgttatcg aaaagcggta ttttatggca
    18961 acgatggtct atttatctgt acatcagcca gtgggatgtc tgcagaaact ttgtacattt
    19021 acactactat ggatggcgga atcacttgga taaaaagtgg aagtacaatg atcaatcagc
    19081 cagtacaaaa tgtcagcttc gttacaactt ctttaggttt tgtttcgaca cgtgaaagtt
    19141 tgttttatac aaacaacgga ggacgctcat tcaaagaatc agttctgtcg attccggaaa
    19201 actatcagac aggggggata gatctttttc aatcaccaaa tgaagttact caaataagcg
    19261 cgaatacgtt agagacaaaa ttttatttgt tgaaaaaagg accaatcgat gcagggaaaa
    19321 tgtttgcctg cctcttccgt tcaactgata acggggaaac atggcaattc gttcagcaac
    19381 tatcgcaagt agaacaagga gattaaagaa gagagattgt gagcctgacg ttcagcaccg
    19441 agtcacaaga aacaaattca aaaaacagct tctcatattt gttgaatagt gtaactcgtg
    19501 attcggagtt gacaagagca acaagaagcg attttgaagt atagcttctc gtattttaca
    19561 agatcgtgtc ttattgccga taggttgtct cttgaacacc gtttattcgt aaaaagggat
    19621 tgtgacaagt cttttgtcac tacttaccga acgaaactga aggagctatc caaaaagtat
    19681 cattagtatt attctttgtg tttctagtgg caccactagt acatttaaaa aagctatcga
    19741 tcatggacta atcatacatg atcgatagct ttttagataa tgtttgttac gctatctgaa
    19801 attgactatt ataaagactg gcataaagcg ttggtgattg gagtagttca gaatgtgttc
    19861 ctttttcgac gatatcgcca ttcttcatta caaggatcat gtctgcattt tcaatcgttg
    19921 acaaacggtg tgcaatcaca aaacttgtcc tatcttttgt cacagcttcc attgcttgct
    19981 gaatcaatgc ttctgttcgt gtatctacgc tagaagttgc ttcatctaaa ataacgacag
    20041 gaggattcgc tagaatgact cgagcaattg tcaataattg ttgctgtcct tgagataacg
    20101 tgccgttttc gctagaaatg atcgtatcat atccgtctgg cagtgttcga ataaagtgat
    20161 cacattgtgc gatttcagcc gcttcgataa tttgttctct tgtggcatcc attttcccgt
    20221 aggcgatatt atcagctacc gttccttcaa acagccaggt attttgtaaa accatcccaa
    20281 aagaacgacg tagttctcca cgtgaaagct tggtaatatc aagaccgtcg aattcgatct
    20341 ttcctttatt cagttcataa aaacgcatca gcagattgac taaagtcgtt tttcctgcac
    20401 cagttggacc aacgatcgct accgtttgtt ttggctttac tgaaaaatcg acttgattca
    20461 tcaatatttt atctgatgtg taaccaaact gtacattttt gaaagctatt tttcctttcg
    20521 gttgttctaa aagtcttgca tctggaaggt ctggaatttc atctgtttca tctaatatct
    20581 caaatatcct atcgattgct gccattgcgg attggatcga gttgatcaca taagaagcgg
    20641 tagaaattgg ttcagaaatc tgattgatgt actgaagata agcttgtaag aagccgatcg
    20701 tcacaccacc tgatagaaca agcatagcac cgaataccgc acttatgatg aaggcgagtt
    20761 gattaatgaa acgaatggcc ggatagatag caaagttcat aaattgagca cgtttaaaag
    20821 cgttgtattg ctttttattt acttcgtgta tagcagcttc tgcatgagct tgctgattga
    20881 atgttttgac cactagatta ccagctaaga tttcttccat tcgattattt aaaacaccca
    20941 gttcatactg attctgttca gaaatctgtt tgtttttgtt cgcaatctta gttgtaacaa
    21001 ttgaactgcc aacgatcagc aataagacga gcaaagtaag cttgctttcg atataaaaca
    21061 gcatcagacc agcagcagct attgttacga cagaagtaaa aaattgattg atacctgtca
    21121 ataacacttg agaaagttga ttgagaccgg tagttgtccg actaatgatg tcacctactt
    21181 gatgattgtc aaaaaacgac atcggtaatg ttttgaattt ttttgtgatt tcttttcgca
    21241 ccctcaatgt gatcttttcg cttaacgctg ccattgtccg ttcctgaata aatgaagtga
    21301 tgctgcttaa gactgaacag ccgatcagca ataagacagg gaacaacaat gcttgtttga
    21361 tatcactgaa agaaagctgt ccaatacctg tttttcttat ttctgataag agatcatcga
    21421 tcccgattcc catgatcaag ggcatggcta cgactaatag gttcccgaat aaactgcata
    21481 gaaacaatcc gtaaaaatat ttatgttcag gtttgatcat tttccaaaaa cgtatcaaag
    21541 cacgcgtgtt caacgttttt ttcttttcca tcgtatccct tctttctata ttccttgtga
    21601 ttttgcaaac tcctgataag tttggcaatt agacagtagt tcttcatgag taccttgtcc
    21661 aacgattttt ccttcatcta aaacaatgat gttatctgct tgttggattg tactgaggcg
    21721 ttgagcaaca atcacgagag ttttctccga catgtgttta tgaagggctg ctcttaatgc
    21781 tgcatctgtt ttatagtcta aagcggagaa actatcatcg aatacataga tctctgctgg
    21841 tttgatcaac gctcgagcaa tacatatccg ctgtttctgg ccccctgaat aattagaacc
    21901 gccttgagca acaaagctgt ccaatccgtc aggaagggtg tccactagtt cttctaattg
    21961 agcgatcttg atcgctttag acaactcttc tgttgaggca tattcatttc ccatctgcaa
    22021 gttgcttaaa attgtcccgc tgaataagaa agccttctga gggacataac tgatgtggga
    22081 gcggatctgt tcttgagtca tttgagtaag aggaatacca ccaagggtta cttttcctat
    22141 cgtagggtca ctaagtctca agagaagttt cgccaaacta ctttttccag atccggtccc
    22201 gccaacgatc gctgttgttt ttcctttagg tattgtgaaa tcaatatctt ctagaactgg
    22261 atcagagatt tcagtatatt taaatgtgac atgttcaaaa gcagctgcat ttgtctgatc
    22321 aaaggttggt tcagctactg ttttgatcgt ctcttcctca atttcgatct ctgcttgcag
    22381 tatttcttct atccgtcgta atgaggcaaa cgatttaggg ataatgacca ataccatagc
    22441 tgcgatcatc aagtaagcaa gtgtcagcat agagtattcg actacagcag tcacgacacc
    22501 gatttgtaat gctccttctg ctacaagatt tccgccaaac cacaaaatag aagcataaac
    22561 gattcccatg agcaaaaaag caattggagt gacccaagca aatattcggt tcactttgat
    22621 catttgatta gcatagtcag caaagctctt attcgttcgc ttttcttcat atgattgatt
    22681 atcaaaggca cggatcatat taatcccagt aaagaattct ctcaatgtga tggtgatccg
    22741 atccattttt ggctggatac tcaaagataa aggtgcccct cgtttcatca gtcgataaac
    22801 aatccataca taaaaaacaa cagagatcaa tgtaacccat gttagtaata gagaataacg
    22861 aaacatcatg agaatggtga aaacgcaaat aaccggtgct ggtaagatca tttggcaaaa
    22921 taaaacaatc atttgctgga cattatcgac atcattcgtc attcttgtca aaagagatcc
    22981 agaactaaaa cgactgatat ccttcattga cagctgttgg aatttacgga aatatttctc
    23041 ccgcgtttgg aatccaaacc tagcggaagc caatgctgaa aagtaactag aggcaactgc
    23101 agcgattgtt cctagaaacg ctacaagcag catttcaact ccaatttttt ttataactga
    23161 ggcttcgcca cttgctatac ctgtgtcgat cagctttgct actaattttg gtacacctaa
    23221 tgtaccggcg atttgtaaac agatcatcac aaaggtaagg agagcgagtc ctttgttttt
    23281 ctgtaagaat gtttttaaga tagacatatt attcctcctt ttttcctgat acttttcgat
    23341 tctatacctt caagtaactt gaaggtcaat agaaaaaaga ataaactgaa aaagaggtga
    23401 gaaaaaatga aaaaaatgta tacgattggc caagtatcgg aactatttga tttgccaaaa
    23461 tcaacgatcc gctattggga tgaacaagga ttaatccgtt caagtagaca agaagagaat
    23521 gattatcgat tgtttgatat cgatgatatt tttatgcttt atgatatcgt tttttataga
    23581 aaattagata taccgatcaa acagatgaag aatttatatg gaaaaacatt gacggagtta
    23641 tatgagacac ttgatgaaac agaaagaaga atccataaag aactggtggt gatgaaacaa
    23701 aaacaaaaag agataaggga gcgaaaaaaa cagttgaaat tgatgatcga tacaaacgag
    23761 gaagaatttc ctgtagaaga gatccctttt gactgtatga tctcaacgga gtttgaagat
    23821 attgtggaaa tcaaaaaatt tctacctaac tattcaagct ttgggatgat gagtatgcca
    23881 gcttccagtt cacagacgat gtatggattt tttatcgacc ctagtgaagt acatttattt
    23941 actcaagacg tgatttggga gaaaaaagat acggctgttt atcgtcgatt cttattgaaa
    24001 tccgagatga accatgcgga acgtaataat attttagaaa tcagagaaag aatgtatgaa
    24061 aaaggatgga aaacaggaga agtgatcggc cagtatctat tgacgaatac ggatgaaaac
    24121 aatatcagaa ctgaatatta tcatgcatgg atagaaatga aaaaatagga aatatgtgtt
    24181 taagataact cgaaaatgat ggttgtttta gttataaaga aaaattttct ggttcgatta
    24241 cgggtttaat gtgggggatt attagtcgtg gatagataga attttagttt tttagaggaa
    24301 atatgtcttt aaaaatggaa tggttgcaat tcttagcgat atatacgatg taattgtcct
    24361 cttaaaaaag tatggaaaaa taattgtatt gggtgttatg tataattcat ggtgaactga
    24421 gactaatgag aagaaaaatt catattgtta tgagtgagat tgtatcagat gagaatgata
    24481 aattaaatag gtgcataaaa gcattacact taaaatacat tgttgcttac attattacaa
    24541 tatgttaata aggcaaaaat aaatagatgg attgaataaa catatttttt aatcaaatag
    24601 tccctactgt gactttcctc agctatcggt gatactaccg atagcatttt tttgcttata
    24661 aaataattat aagtatttag agatttttct tctaacattc ttcaaacaag aaaaatcaca
    24721 aaggt
//
LOCUS       DAZULR010000038        24579 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.038, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000038 DAZULR010000000
VERSION     DAZULR010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24579
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.038"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(154..552)
                     /locus_tag="ACG8ZV_001875"
     CDS             complement(154..552)
                     /locus_tag="ACG8ZV_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030234 - enzyme regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006808 - regulation of nitrogen
                     utilization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HFS4997189.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(549..1322)
                     /locus_tag="ACG8ZV_001876"
     CDS             complement(549..1322)
                     /locus_tag="ACG8ZV_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HFS4997190.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(1319..2002)
                     /locus_tag="ACG8ZV_001877"
     CDS             complement(1319..2002)
                     /locus_tag="ACG8ZV_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HFS4997191.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(2169..3056)
                     /locus_tag="ACG8ZV_001878"
     CDS             complement(2169..3056)
                     /locus_tag="ACG8ZV_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4997192.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(3053..3922)
                     /locus_tag="ACG8ZV_001879"
     CDS             complement(3053..3922)
                     /locus_tag="ACG8ZV_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4997193.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(4059..5345)
                     /locus_tag="ACG8ZV_001880"
     CDS             complement(4059..5345)
                     /locus_tag="ACG8ZV_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFS4997194.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            5618..6196
                     /locus_tag="ACG8ZV_001881"
     CDS             5618..6196
                     /locus_tag="ACG8ZV_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFS4997195.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            6196..7125
                     /locus_tag="ACG8ZV_001882"
     CDS             6196..7125
                     /locus_tag="ACG8ZV_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4997196.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            7122..8858
                     /locus_tag="ACG8ZV_001883"
     CDS             7122..8858
                     /locus_tag="ACG8ZV_001883"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFS4997197.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(8921..9757)
                     /gene="pheA"
                     /locus_tag="ACG8ZV_001884"
     CDS             complement(8921..9757)
                     /gene="pheA"
                     /locus_tag="ACG8ZV_001884"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HFS4997198.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(9754..10263)
                     /locus_tag="ACG8ZV_001885"
     CDS             complement(9754..10263)
                     /locus_tag="ACG8ZV_001885"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HFS4997199.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(10256..11551)
                     /gene="aroA"
                     /locus_tag="ACG8ZV_001886"
     CDS             complement(10256..11551)
                     /gene="aroA"
                     /locus_tag="ACG8ZV_001886"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HFS4997200.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(11564..12655)
                     /locus_tag="ACG8ZV_001887"
     CDS             complement(11564..12655)
                     /locus_tag="ACG8ZV_001887"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HFS4997201.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(12672..13838)
                     /gene="aroC"
                     /locus_tag="ACG8ZV_001888"
     CDS             complement(12672..13838)
                     /gene="aroC"
                     /locus_tag="ACG8ZV_001888"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HFS4997202.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(13840..14904)
                     /gene="aroB"
                     /locus_tag="ACG8ZV_001889"
     CDS             complement(13840..14904)
                     /gene="aroB"
                     /locus_tag="ACG8ZV_001889"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HFS4997203.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(14937..15959)
                     /gene="aroF"
                     /locus_tag="ACG8ZV_001890"
     CDS             complement(14937..15959)
                     /gene="aroF"
                     /locus_tag="ACG8ZV_001890"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HFS4997204.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(16618..17592)
                     /locus_tag="ACG8ZV_001891"
     CDS             complement(16618..17592)
                     /locus_tag="ACG8ZV_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HFS4997205.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(17573..19456)
                     /locus_tag="ACG8ZV_001892"
     CDS             complement(17573..19456)
                     /locus_tag="ACG8ZV_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HFS4997206.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(19474..21699)
                     /locus_tag="ACG8ZV_001893"
     CDS             complement(19474..21699)
                     /locus_tag="ACG8ZV_001893"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HFS4997207.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            21813..22847
                     /locus_tag="ACG8ZV_001894"
     CDS             21813..22847
                     /locus_tag="ACG8ZV_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFS4997208.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(22914..23927)
                     /locus_tag="ACG8ZV_001895"
     CDS             complement(22914..23927)
                     /locus_tag="ACG8ZV_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFS4997209.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(24005..24193)
                     /locus_tag="ACG8ZV_001896"
     CDS             complement(24005..24193)
                     /locus_tag="ACG8ZV_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HFS4997210.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
BASE COUNT         7065 a         5341 c         4397 g         7776 t
ORIGIN      
        1 tagcatattt tgaaaagaaa gtctgatgct tagagtagaa tttcataaaa atttactatt
       61 tcataagtat tcacgagaaa aatacaaaca aaaaagcgga aataacgctc atccgccttc
      121 ttgtttgtgt ttatttcctc ttcaaacgct tgtctatgat tcagactttt ctctatcgtt
      181 attttcatct aaaagttctt gcattccgat aatttctcga tattgatgaa tcttagtgat
      241 accaatgact ttgtctacat caatactaaa acaaatacca ttacctggaa tatcgatgtt
      301 gatgccttga ccaatcgcat ccattacttt attcgtcaaa ctatcgggta ctaatgtcaa
      361 cacaatatct ttttctggcg aaatgtccaa acctaaaaat ttccctgaat catgtacacc
      421 agaacctctt ccatgtaaga tcgttccgcc tgctgcacct gcttcttttg aaaagtcgat
      481 aacatcttcg cccattcctc cgtcaacgat cgtcacaatc atgtgaagat tcaatgctac
      541 aagatctttc atttgctttc ccccaatttt tgcaatcttt ctttttcgat tctgtctttt
      601 tcatcttttc gtttataaat atatcctagt actaaagtgg ataatattgg tgtcaatgca
      661 atcattgcaa ccacaccaaa cccgtcaatg atcggatctc ttccttcaat ttgtgcagcg
      721 attgccacgc tcattgataa aataaatgtc gaacacatcg ggcccgttgc tactccaccg
      781 ttatcaaaag ccattgctaa aaagatcttg tccacttttc gtcctaaaat aaatgctagc
      841 ccgtatcctg ggatcaagaa ataataaaga gagaatccga cgagcaaacg ccacatagac
      901 aatcctactg ctgcgccgat cccaattgaa attaccatca gcatgatttt cgatcggatt
      961 ctcccctcgc tcaattcttc aacctgtttg atcattacat gaatcgccgg ctcagcaaac
     1021 cctactaaga accccattaa aaagccaagg ggaaccagta tataattgta aggcaatccc
     1081 gcaatagcac tgcctaaatg ctgtcctacc ggtacataag ccatattgac tccgtgcagg
     1141 aaaaggatca acccaatagt cgttatcaag aaacctttca taatgtcaaa gaaacgcttt
     1201 ttgcgcatac gaaaactaat gatattcatt aaaacaaata ggattacgat aggtgccact
     1261 gccaaaatga cttccatggt aacgatttcg attccatcta tcacttgctg ccagaaactc
     1321 attggaagat cacccccaaa atcatcacgg caagaatcgg ccctaacgaa gcaataccga
     1381 ccattccaaa actgtcattt tcatttttct tttgtttgat catactagtc atccctccgg
     1441 caagggccaa gataaatgga acagttactg gaccagtagt cactcccccc gaatcaaaag
     1501 caatcggcat aaattcggaa ctggtgaaaa atgaggcgat caaaacgcct atgtagccta
     1561 tagccatcaa ttgataatag gatagcttga atacgacccg aagcagcgca aaggctagaa
     1621 atactccagt gccgacgctg acgatcccaa tcagcaacac tctgccaatc tctccgtcag
     1681 atatatcata tacttgttgt cccaaaactt gcacggaagg ttcagcaatc gtgatcacga
     1741 tcccgatagc aaatcccaaa ctgaccaaaa cggtcaaact tttctttttg atcatatatt
     1801 tccctactag atctccgact tccatcatag aataatctgc tccaaacaaa aagagcgtca
     1861 ttccgatcat catgattgcc gcaccaacca gaaatgaagc gaggtcttct ccttctaacg
     1921 gtgcaaaaac aaacgttaaa atgacaatca ggacagtcat cggcaatata gcagcaatca
     1981 cttctttaaa attttttagc atgtatcctc ctcctttact ctttaagttt accttaaaat
     2041 gaaagagttt tcgagcacaa acttaaaacg ttatcattta atttttctca acataaaata
     2101 acacacgtcc caaaagtatc tttttacttg gaaaaatgac tttgaaggaa cgcgcttatt
     2161 gtgttttttt attttacaga gccgatcatt ccttgaacga attgcttttg caaaacaaaa
     2221 aatacgatgg cagttggtaa agtagcgatg actaatccag ccatgatcat tccatagtct
     2281 ggtgtatagg aagcacccat agcagataaa acaagcggaa ccgtccgttt atcaggagat
     2341 tgcaaagcta ctaagggcca taaataattg ttccagctac tcatgaatgt gatgattgca
     2401 gccgcggcat aggtattttt agccgtcggc atatacactc taaaaaaaat acttagttct
     2461 tttagaccgt ctaatcgagc ggcttctact agatcttttg gaaaagattt aacattttgt
     2521 cgaaagaaga agatcaaaaa agcagtgcta acagatggca ggatgacaac caagaaactg
     2581 ttgattccca aaaccgttcc gttcaattgt gaaaacattc gatataaagg gatcatcaat
     2641 gccgcaaaag gaaccatcat cgatagcagt agaatattga aaattaggtc ttttcgttta
     2701 ctttgataaa tctcaaatcc atatcctgcc attgacgaaa tcagcaatgc aaacacagtg
     2761 gtcaccaaag cgatcatcgc tgaattccaa agggaacgag taaaattcag ctcattggaa
     2821 aacaaatttt gaaaattgat gatcaagtta ctgccaatct ttatttttcc cgatgtgata
     2881 tccacgggtg tattcgtcat tcccaaaacc atccagacaa aagggaaaat ggaaataaat
     2941 gataggatgc ttaatgctgt atactttaat actgacccaa ttgtcgaacg aagttctaat
     3001 gcttgttttt tgacgttggg gcgttcgatt gtttcttttt ctaccatatt tttcatcgac
     3061 tttctcctcc tactttcgtt tggattatcg acaatatcac aataaaggaa acaataacaa
     3121 aggaaactgc tgccgcatat ccaaaattag gcgtgaattt ataactcaaa ttatagatgt
     3181 attgagatag ggtggtcgtt gcatttgctg gtcccccgcc agtaatattt tgtacttcat
     3241 caaaaagctg caatgtcccg atcgtcgaag taatggaagt aaacaaaatg attggtttta
     3301 aatttgggat cgtcactttg ataaactgct gccatttaga agcaccgtca atagatgctg
     3361 cttcataaat ctccgaatca atattttgca tgcctgaaag gaaaaaaatc atattgtatc
     3421 cagtccaacg ccaagtgatc gaaagaatga tcagaactct cgcccaaatt ggatgagtca
     3481 accagccaat cggtgtgtca atcataccaa tgcccaacaa caagttgttt acaaggccag
     3541 attgagaaaa tagacttttc atgatcagag aataactgac catcgaagtg atacatggaa
     3601 gaaagatagc ggttcgaaac aaccctttat atttcaactt tttatcattt aaaaggttgg
     3661 aaataaaaag tgctagaaac aacatgatcg gtacttgtac aagtaaatac aggaatgtat
     3721 taaaaaaagc ttttttaaaa gttgcatctg tcaacatccg ctgataatta cctaacccgt
     3781 taaatgtcat attgacaggg ggaccacttt gaaaagacgt gatcaaagcc aaaaccatcg
     3841 gaataaaaac catgattgat atcaaaatga ctggcaagat taaaaaagca tgcccgtttt
     3901 tgaataaatc tttctgcttc attcttttcc ctccaattct atcattgatt atctacatga
     3961 aaagacaaga aagacaatat ctgtaaggca gacgtgatct tttttgtctt ttcgtttgtc
     4021 tgatgaaaaa gcgaagaaat tcactttttt accaccgatc aattagccaa ttgtgcttct
     4081 acttgttttt gtgtatctgc tagtaccttg tctgtctctt ctccattgat gattcgatga
     4141 agagcttcag ctacgactgc ttcaattgca taggtctcat gtccgtaatt cacttctggt
     4201 atttcagatg tccatgttga aaaatcgtca aagatctttt gaccactgta aaattcagaa
     4261 gcttcttgat aagcttcttg ttcattcgcg ctaagcatcg tagatactag tccgatttct
     4321 ttcgcaagag tgcccatcag ttcttcattc gaagcaaacg ttgcttctag gaaatctttc
     4381 gctgaatctt ctccagctac tcctttgatc acataccagc cagcgccgcc aaggttagaa
     4441 gcttgcgctt tttgcagatt ttctggaagt gcaggtattg gtgcaatctt ccattttcca
     4501 gattggtttt ctgctccttg gatcgttgaa gaataccaag cgccagttgg gctagaagct
     4561 actgctcctg attgtatcgc agttactcca gcattccagt cagaggtttg ttcgactaga
     4621 tcttctttca aaagagtggc aaacaattca agaccatact ttaaagatgc attgtcttgg
     4681 atcgtgactg tctccccatc ttcagatgta taccattctc ctgcctgttg cataatcatc
     4741 cttactcgac caaggtcaga aggattgact tcagcgattt tctttcccgt cttttctttg
     4801 acatctcgcg ctacttgaat atactcgtcc cacttcagat tctccatatc ctcttctgta
     4861 taacctgctt ctgccatcag atccgtacga tagaagtttg ctgttacgcc cgaatcgaaa
     4921 ggaacaccgt atattttatc tcctactttg tttaccgcaa atttatacgg tgcaaaatga
     4981 tcttccttta caatagcaga caaattagcg aatgcatctg gataagaagt caaatagcct
     5041 tgtatcctat aatcttcaat caagacgata ttgggcaatc cttctgtatt cccgctcgct
     5101 aaagcggtgt tcagtttctg aacgatatca tcctgagaca tcgtaacaac ttctatctct
     5161 gtttcttcgt tctcataaac tttttttgct tcattcactg ctttgatatt gaatgtctca
     5221 tcccacgccc agacagtgac tttttcttct ttgtctgctg tactactagc acttccgcat
     5281 cctgttaaga aacctgatgc tgccgctaaa caaacgactc cagcaattaa ctttctgatg
     5341 ttcattttta tccgctcctt ttccatccat tagttgttta cgtttgctac attcatcata
     5401 ccaaaatttg aaaacggttt ctttattatt cagatacttc aaaaatttct cctaaaataa
     5461 taaaaaaata caaatcaact atgacaaaag gaataatctt agcatctaga ccaaagatcg
     5521 aaatggtgag gtttctttaa aataaaaata tccttgcatt ttctcctaga aataagtatt
     5581 tttaaattac aagactattc ttaaggcggg taaaaaaatg ccaatacgcg taattcttat
     5641 cgatgatgaa cagacgattt tagatggaat gaaacagttg atcaattggt ctgagcacgg
     5701 gtttcaatta atagggactt tttccagtcc gctgaaagcg cttgattttt ctttggtaca
     5761 tgcaatcgat atcgtggtca cagatgtaat gatgcctgaa ttaaatggaa tcgaattatc
     5821 gcggctatta aaacagcaac aacctgaaac acagatcctt atcctctcta gctatgatga
     5881 atttgatatg gttaaagatt cttttaaaga aggcgtcgct gattatcttt taaagcctcg
     5941 attgagtcct gatttttttc taaattcctt aactgccgtt tcacaaaaaa tcaaaaaaaa
     6001 gcccaacaaa agcccaatca ccaatcgtta tgagcagatc tgcgagaatc tttcacagca
     6061 gattgctgga caaactcgtc cattgcttga ccctcttctt tttgaacaca ccttgttttt
     6121 ctgttatata ccgaaaaacg gccattcagt tcaaaacaag gctctaaaca aaaacagtcg
     6181 atcacccatt cattgatgga tagcgacgat tcgtttacta tttatcctgt ttctaccttt
     6241 tcggaagaat ccggctatgt aatcaatact gattccaaag atacacttag gaagtttgtt
     6301 caaaagtttc gtcaagaagt ttttccaggt gatttttttg ttgtttctga ttcttttgca
     6361 atccaagata tcaatgaaat attccaagag atcagaaatt gcaccaaagg acaacgtttc
     6421 tatcataagg gaaagaacct tgcttatcag catgaacttc ttccgttatt aaccaaccac
     6481 gagcagcaag caagtagtta tttaacaaaa atcgttcata aagactacgc tttagctgtc
     6541 aaagaacttg agaatttctt cacgacgata ttggaacagc ctattgatcc agcttatttg
     6601 aaacatgagg caatcaatcg tttctatgca ttactcaacg ctttggctga cgagcatgtt
     6661 gggaatgaag aactttcttt gctcaagatc gcccttcctt ctttattagc cgatgctgag
     6721 tatttcgaag atttttctat tcttgtcaaa gaaacacttg agaaactcac ccacttttct
     6781 gcaaatgcaa aaaaagacaa tttcgatatc ttgactttga tctacgagtt cgtccaggaa
     6841 aattatgaga aagaaatcaa tttacaactt ttatccgaaa aatatcattt ttcatatagc
     6901 tatctctcag ccatctttac tgaaaaattt ggtatcaact tttcaaaata tctaaaaaaa
     6961 gtccgtatca gtaaagccaa gctctttttg acggaaacac ggcttacttt gacggaaatc
     7021 tgtgagaaag tcggctatac cgaactgggt tatttctcca gagtttttaa agaagagaca
     7081 ggaatgacac cttctcaata ccgtaaagga acttttgtaa aatgagaaaa aaaatcaaag
     7141 agcatgaact ctttgccaaa cttctgttca ttttgttcat cggtcttttt ctgcaagcca
     7201 tcgtcatttc tttgtttatt tatcatcgat caagggatgc ctatatccag ctgttcaatc
     7261 aatcgaatga tgtggtacta aaaaagattc aatctgaatt tgaaagtttg aatgatacaa
     7321 tcgagaatac attagccgct tttgattcta atccagctgt caaaagctat ttttccaatg
     7381 atccagccca acatatggaa cagcttcagc aactaagaac aatccaaaaa atgaatgact
     7441 ctctttcaaa aatccatcca atgatcgatt acgatgtatt gatctttgga gaaaatggaa
     7501 gaacttttgt cggaaacgac atgctcactg ccgtatctgc cgattctttt tttcaatctg
     7561 cgattgctca gagagtgaat gaacgtgctg ctgatacaca aatgcttttt gcacaccacg
     7621 gattgactct tcgcgataag aaagcaccca gcgtcttctt tgtcaaaaaa ctgaaaaata
     7681 cattgaatca cgtttacgga tatgctgttt tatcgatctc atccaagcaa ctagcgaatc
     7741 tttttcaatc tgtagtaaat cctgagatat cgaagatctc cttcatgaac gaagaacaga
     7801 cgatcatcgc atcaaatgaa gaaaatacaa ttgggagccg atcaatgatt ttcaaaaaac
     7861 taacagtagg tgaaacaacg atttcaaatg gacagcagtt gacccgtctt cctctgtacc
     7921 gccaggattg tacattactc agtcaagtcg atcttcattc tttatctaac caaatgggcg
     7981 tgatttttcc gattattttg tataatatcg tgacacttgc ttttgctggc tcattggtat
     8041 ttatgtattt ggatcgacac acaaaatcga tctaccgctt gattgattcg ctaaaacggc
     8101 tagaggaaga tggcttaaaa gctactgttc ctgtacaagg aagccatgaa gtccaattgc
     8161 tagggaatac gatcaatcaa ttgctaagta atgctcagca tcattatgaa cagacgatcc
     8221 aagacgaaaa gaagaaacgt tcgcttgaaa tccaaactat gcaagcacag atacagcccc
     8281 attttattta taatacgctg actagcttga aatttttgat ttggcagaaa aaaacagatg
     8341 aagcagttca aggaatcgac agtttcatta ctttactaag aagtacgatt gggaaaaaag
     8401 aagaagtgat tccagtcaag gaagaaatca aaagcgtaca aagttacatc gatcttttga
     8461 gtatgcgata tggcgaaaga atctcggcta aaataatgat tcctgatgaa ctgcagtcat
     8521 tatctatgcc gaatatgatc cttcaaccaa ttatcgaaaa cgcctatctt catgcttttc
     8581 acaataaaac gcaaggattc atcacggtgt acggcaaaac aaaaaatcag cttcttttat
     8641 tcgaagtgat tgataacggc gatggcttcg atactgaaaa taccaaacaa aaaaatgatc
     8701 atttttcagg aatcggcatc agccatgtag atgagcggat acgcctaatg tatggcgatg
     8761 catatggctt aacgatccaa tcagtgattg ggacaggaac gactgtaacg atttgtctac
     8821 cgcttcttcc taaaaatcaa tcagaatatc aaaaataaag aatagccaag cgctgatttt
     8881 tttattttaa gttaaataaa tcaatcagta ttcttgactt tcatctacgc gtctcttcta
     8941 ctgtcagcac tggataacag cccaatattt gactttctcc tccgagcatc ttgatttctt
     9001 ggagcgcatt ctctactaat gtcattggac ggtccaacaa caaatcgatc acgaaaaaat
     9061 attctcccaa gctagttttc aatggtcggg attcaatctt acttaagttg atttcccgcc
     9121 agccaaaagc tgccagcatt ttatgaagca tccctggccg attagcaggt agtgtcaaga
     9181 tgacactcat ttttactgga gctgactgct ggctggtcat ctttcggtca ccgacgatcc
     9241 aaaaacgtgt ctggttcaac tcattatctt ggatattctc agctaagatc tccaatccaa
     9301 catgctgtgc tgtttctaat gaagcaatcg ctgctgcgtc ttctttcgga tgttctgcta
     9361 catacattgc tgcagcagtt gttgattctg ttgctactaa aggaacatta ggataatgcg
     9421 tttctaaaaa ctgttgtgat tgtgctagtg cttgtggatg tgaaaggatt tttgtaatct
     9481 ttgttgctgg attgcctaaa agctgctgct tgataggaag aacgatttca cttttaactt
     9541 cgacttctgg atgtttggaa agaagatcga ttgtgtgatg aacagctcct tccaatgaat
     9601 tctctacagg aacgacagcc agatcgactt gtttgcgaaa caaagcgcgc aaacaaacag
     9661 ggatggaagc atacgcagtc aattgttctg taggaaatag ctgacaagcc gcctgataag
     9721 tgaatgaact ttctggccct agatagctga cgttcatatg cttttgatcc tttctataat
     9781 ggtatcgatg atcttttctg gtgtttgatt ggtcgtgttg attcgatgtg tcgcactttc
     9841 ttcataccaa gaaagtcgtt gtgccaataa tgcttttatt tcttctcttg tttttccaag
     9901 agctaaaggt cgaatagacg tttcatcttg ttggatacga tcaactagac agtccgcttc
     9961 tgcctctaag taaagaacaa tcggctgtgt ttttaaaaaa cgccgatttt ctgcactttg
    10021 gacaatccct ccaccagtcg cgataatttt gtcttcattt gacagctttc ttaaaatatc
    10081 tgactccact tttcgaaagc ttttttcacc gtaatagtga aaatattcgg caatcgacaa
    10141 ttggatatgt tcctcaatct ttgtatctaa atctacatac tctttttgta aacattgagc
    10201 taacccttta ccgattgttg tttttccagc gcccatgaaa ccaatcagca aaatgctagc
    10261 catgagcttc tcctcctgac acaagttctg ctaaatcgtc aaaaaatgcc ggataagaga
    10321 ttgaaacagc ttcagctcct tctagttcgc aaggtccatc agctatcaaa gcagctactt
    10381 gcagcatcat accgattcga tgatcgcctc tgctggacac ttttgcgcca tgcagaggtg
    10441 tcggcccatg gatgatcaga ccgtctgctg tcgcttttat ctttgctccc attttctgta
    10501 attcttctgc caccgcatca attctgttgg tttcttttac ttttaattct tctgcgtctt
    10561 tgatgatcgt gattccttct gcttgagtag ccactaaagc tagaatgggc aattcatcaa
    10621 tcagacgcgg aatgatttct ccaccaatcg ttgctttctt caaatgactc gtcttgacac
    10681 ttaaatcagc cgattggttc tgttcattgt gattcgtctg ggtaatcgct gcgcccatct
    10741 cctccaacac atctaagata ccagttcttg ttggattgac cccgacattt tttaacaaca
    10801 gttggctttc cggaacaaga agtcctgctg ctagaaagaa agcagctgat gaaatatcac
    10861 ctggaacagt tatctgttga ccagttaatt tttgcggtcc ggtcactatg atcgttttat
    10921 cttccactgt gatccttccg ccaaattgac gaatcatttc ttccgtatgg ttacgggaac
    10981 gttctttttc aacgattacg gatgtgcctt ctgcttgtaa tgccgcaaac agcaaagcag
    11041 atttgacttg cgcactggct acaggcatat tgtatcggat aggtgataaa gagcgggttc
    11101 ctgtcacagt gattggtaga tactggtcat tttcttctcc ttgcaagtca gcgcccatct
    11161 cgcgtaaagg ttccatcact cgccccattg gacgtttaga caacgaagca tccccgaaca
    11221 gagtagtcgt aaaaggctgt ccagccaaaa tacccatcaa taaacgtatg gtcgtaccgg
    11281 agtttcccat gtcaattgat tcggttggtt ggacaaatga gtggctaccg cgaccatgaa
    11341 tcttgatcac ctcttcctct tcttcgatct cgacacctaa ttgttggaag gcatgtaaag
    11401 tactcagaca atcttctgcg cgcaaaaaat tttgtatagt cgtcgttcct tcagcaattg
    11461 ctccaaacat gatgctgcga tgggaaattg atttatctgc tggtatccta acagtccctc
    11521 ttaatccatg tatttgttgt aataattgca tttatccagc ctcctatttg atccagcaat
    11581 gataactggt attagacata atgattcttt ttgcttgtaa caaatcctgt tggtttttaa
    11641 aactgatttg cagtattcct aaaatatctt ccctggtctc ttggatcttc aaattaatca
    11701 aagaaactcc cgcttttccg atcagtccag ttacttctgc aataacgcca ggttcatctg
    11761 gcacatcgat aaataaatca aaaaaggcag gaatcgcgcc ttgcttatgg acaggcaact
    11821 ggtctcgact ttcttttgcc cgattgaaaa aagaaaagat ttccgattgg ttctcagtca
    11881 tgatccattc tgctatttgt gtcatttctt gttgccaatc tgccaatcgt tccaataata
    11941 tctgcttatt gctcaacaaa atatctgtcc acatgacagg atctgaggaa gcgatcctag
    12001 tgatatctcg aaagcctcct gctgccagtt gtttggctcg cggatactct tgattgaatt
    12061 gttctgcctg attgactaag ccagctgcca gaatatgtgg aaaatgactt agcattcctg
    12121 ttatacggtc atgttctctt gctgtaagag ttacatattt tgctttggtt ccgcaaaata
    12181 gttcttgcag tttttcaaca tcttttttcg tcttttccaa aggtgtaaag atgtaatagg
    12241 cattttcaaa tagtttagca tctgctgcct gtatacctga tttatgagaa ccagccattg
    12301 gatgtccacc gacaaaccga agatttttct gctcagcgga tgtcacgact tgctgcttcg
    12361 tactgctgac atccgtaatg atgacgtgat cagacaagtt gattctttca aggacatcaa
    12421 gataagctaa ggttgtacgg acgggaacgg ctaataagat aacgtctgct tgttctgcac
    12481 ctgtttcaaa atcacttgca acgtaatcaa cgatctgctg ttctactgct tgctcacggg
    12541 tttttgactg actatcccaa ccaactacta tcagttctgg attggtctga cgaatacaaa
    12601 gtgccataga agcaccaatc agtccaagcc ccacgataaa aacatgttgt gccatcttat
    12661 ttgccccctt tttagtaatg tttcaagtag tcacggtact ccttcactgc agctttcaac
    12721 tcaacaagcg aatcacttgg gaattttgac aatagctctg tcgctaccac agtggctaca
    12781 acattttccg caacgacgct agctgcagga actgctgtac tatccgaacg ttctacactt
    12841 gctttgtaag gttcttttgt atcgatatca acactttgaa gtggcttgta caatgtagga
    12901 atgggtttca tgaccccgcg aatgacaagt ggttcgccat tggtcattcc gccttcgaag
    12961 ccgcctagat tattggtacg tcggaaatag cctctttctt cttcccatag gatctcatcc
    13021 atcacttctg agcctggtaa tgaaccagaa gtgaatccga ccccaaattc tacgccttta
    13081 aaggcattga tactaaccac agcttgtgcg attttggcat ctagcttcgt gtcccattgt
    13141 acgtagcttc ctaatccagc tggaacgcct ccaacgagca cttctacaat tcctccgatc
    13201 gtatctccat ttttctttgt ctgatcgatc aaatctttta ttctttgctc aactgctgga
    13261 tcaacaactc gtacttctga cgcttcagaa atttctttga tttcttgaat cgagatattt
    13321 ccaggtattt ctgcttggat tccaccaaga caaatcacgt gtcctgctac gatgatgtca
    13381 agttcttcca gaattttctt ggcaattgcg ccgattgcta cacgcatggt cgtctctctt
    13441 gcagaggacc gttcaagcac attccgaaga tctcgatgat ggtatttcat accgcctacc
    13501 aaatccgcgt gtcctggacg cggacgtgca actcgccgca gtgattggtc tttttcaggc
    13561 acttctgcta cagacatgac agttgtccaa tttttccaat ctttattttc taccactaaa
    13621 gtgacaggtg aaccaattgt tttgccgtga cggatgccag acgtgatccg aacacgatct
    13681 ttttcgatct tcatccttcc tcctctgccg taaccagctt gtctgcgagc gagttcgtga
    13741 ttgatttctt cttctgacag aggtaatcct gctggtagtc cttcaataat ggctgttaat
    13801 tctggtccat gggattctcc cgcagtcata taacgcatct tacagtcctc ctaagtaatc
    13861 tttgaatgtc tctgtgggaa caggaacgat ttttgcttgc ccaatctttt ctagcaagat
    13921 gatattcaat tggcttcctc ttgctttctt atcatgggtt atcgcgtgga ataattcatc
    13981 tggatgactt agatcgtacg taatcggcag atggaatttt tgaagtatcc tttctaaagc
    14041 agctgtcgat ccagttggag acaagccgat tttttctgca tgagaagtga tggctaccat
    14101 tccaatagct actccttctc catgactgac taccccatat cctgctgtat tttcaattgc
    14161 atggccaatt gtatgaccaa aatttaaaat aagtcgattt ccttggtcaa agacatcttc
    14221 ttccactact tttcgtttga tttccaacgt agcagtaatg attggaacag catgttccag
    14281 aagatctttt tcgtctttca gctcgttcag ctgtttccaa agcgttgcat ctgctatagc
    14341 tgctgatttg atgatttcag cgattccttc tcgtaaacga cgtaccggca aagtttttag
    14401 aacctcagga tcaatcaata caccagctgg ctggctaaat gttccgacaa ggtttttcgc
    14461 tttgtttgta ttgactgctg tcttcccgcc aatactagaa tctacttgtg caagtagcgt
    14521 agtcggaatt tgaacgaaat ggatcccacg catgaacgtc gaggccacga atgctgctag
    14581 atcacccacc attcctccac caagtgcaag tatcccatcg ctgcgggtaa aatcattatc
    14641 tgctaaaaaa tcgtataact cagctgcttg ttctaaagat ttactggtct cacccgccgg
    14701 tacgattgaa aggactggtt caaaattagc ttgtctcaat tggaacatga ttttttctgc
    14761 atatagtgga gcaacgtttg tatcagtgat cacagctact ttttgaggtc tccaaatcgt
    14821 ttgaagccat gatccagcct gttctagtgc gcctttttca atatgaatat cgtatttttg
    14881 gttatcaaca tgtacagtaa gcattcgttt cacttctttc ttttaaaaag ctggaattaa
    14941 tcgagtgtct gaatcttttc cattgcttct ttcatgatcg caacttcttt catcatgcgt
    15001 gagtaagtct tttcattcaa cgattgggga ccgtctgacc aagcatttgc aggatcagga
    15061 tggatctcta cgatcatgcc atctgctccg cttgccacac ccgcacgagc cattggtggt
    15121 acaagttccc aaattcctgt accatgactt ggatcaacaa tcacagggaa atgagttaat
    15181 tttttcatca atgggacagc acttaaatca aacgtattac gtgtcgctgt ttcgtaagtc
    15241 cgaatcccac gttcgataaa aatgacagga gatttgtctt cgactgcaat gtattctgca
    15301 gcattaagcc attcattgat cgtaccggaa attccacgtt tcaatccaac aggtttacct
    15361 gttttaccga cagcagatag cagtttaaaa ttttgcatat tacgtgcgcc aatctgtagg
    15421 atatcgctgt actcagccac catatcgata tgcccttcat ccatcacttc agtaatcact
    15481 ttcattccaa attcatcagc cgcttgacgg atgtatttca atccttcttc ttctaaacct
    15541 tggaaagcat atggagaagt acgtggtttg aaggcaccac ctcgcagaat ttttgcgccc
    15601 ccggctttgg ccattcgcgc acattctctg atttggtcta atccttcgat agaacaagga
    15661 ccagccatcg tcacgaaact gccgtcacca atttttactc cgtctacatc cacgactgta
    15721 ttgccaggat ggaattctcg agaagtcaat ttgtatgtgt ttaaaatacg cacagcattt
    15781 tctactcctt catagcgtgt aaatgctcct tcttgtaaac ttcgcgtatc accttttagt
    15841 ccaatcacta ctcgttctgt tccttgatcg attgagactt tgaatccttc tttttcgata
    15901 tgatcgacga ctttttttat ttgttcttcc gttgcttctt ttttcataat tactatcatt
    15961 gtttttcccg ctttcttttg tttacttatc tatcttggct gattttctct actttttcaa
    16021 ggtggtttta cattaattcc tactaaatga ccgtgtcctg ttgttctcat tttcgctcct
    16081 tctttcctac ttatgaccca gataatcaac aaaaaaagat gtccctgtag gaaattgcct
    16141 ctacagtgaa catcttcaac gagccttaaa aagcgctgca aaaatataaa atagccacta
    16201 tagatgaatt tctctacgtg gctgtaagtc gtgtttaaaa atctttagcc atcatagata
    16261 caaacctggt ttgtttgtac ccacgaagtc atgaatacaa acctatctaa aatagctaaa
    16321 gtaatacgta ttcagttttg taagttttct agatttcata aaaaatcgct ccaaactgat
    16381 gtaagaattg tacctagtat agacataaaa aaatcgactg tcaatcattt ttatgaaact
    16441 ttttttaatt ttctgatagt taactttgtt tttcagaaaa ataacaattg gttttattga
    16501 agaaaatagt catgaacaaa agtatctgag aactttttta ctctcttgtt catgacatat
    16561 agaataaagc agctttgtct tgtaaactcc gtttttcaaa taataatcta aagattgcta
    16621 ctgaataata aagccgattt catggtcctc ttcgctgctg attcggtaag gtgactcaac
    16681 atccgctccc cagctattga tacccccgac tcctcttact tttgcaaaaa tcgtaagaac
    16741 cgttcgtctt tctggcggta gttcttctat atgtgttgcc tgttccagtt cttctgcttt
    16801 gaatggtaaa gcggaaaaag caaatggcgt atcctgctgt tcaaatcgca acgaaaaatc
    16861 ttcttgatct ttatccgtat tatccaacgt ttgatttctt gttagttcta cccatttcgt
    16921 ttccatatgc atgccgcatt cttggggaac aaggtatggg gaaacgggga gtcctgccac
    16981 tttataaata ccttcgacac caccagccat ccgatccgga tatgtttccc ctgataggcc
    17041 ttcatactca aaaaattttg ctttcgttgg cataatgaac cttaaaccca atgcgggtaa
    17101 ttccggtaat cctttttgtc cataataatg catattgaca agcattttac cctctccagc
    17161 gatttggtag gaaattgtca cttgggtttt tggtactgtg ttgatttcca gtgtaaaaat
    17221 gatttcaacc gtttcagcgt attcattact tgaatattga ttatttactg gagcaatcgg
    17281 caaatcgatc tttttattgt ccaccagtac ttctatttct ttgacttttg gatacaatcc
    17341 ggctcctaac cacataccgg atttaaatcc aaatccgcta cctctgtcat tatcggtcgt
    17401 tgctcgccaa aaaactggaa gtgtttcccg gtatagccat tcttttccgt ttttattgag
    17461 cgattccagt ccgcctcttg tataagaaaa aatataatgc gtattccccg atttgacacc
    17521 taatgtacag tcgccgaaga cgattgcaac tttttccgta tccatatgac ttttatttac
    17581 tgtatttttc ataataatat cttacctcct gcatggcggg tttttcttgt ccatctgcaa
    17641 aaacgatccc attccctgag aattcatagt cacttggttt atcgtcaaag tcaccgccat
    17701 agcgcatcac ttctctgcct gtgattggat cagtcacttg gatcgcctga tctttaaaat
    17761 cccatatata gcctccttgg tacatttcat aacgatcaag caacgtcatg taagaatcca
    17821 ttccacctaa cgaattcccc atgtcatgca tatattcaca taagatgaac ggtttttccg
    17881 ctttattttc aaggtagtca atgatctctt ctggtggcgc atacatgcag ctttttacat
    17941 ctgaaatcga atcttcgaat gctggatttg gaaaattccc ttcataatgg acaagtcgat
    18001 cggggtctac ttttttgaag taatcgttca tttgtcgaat gttttcttcc gcataagatt
    18061 catttccaag agaccaaaaa agaatacttg gatggttttt taatgtttcg aaattcgttt
    18121 ttgctcgatc aagaacagcc gcctgccact gaggtactgc acctggtacg ttgtaagaag
    18181 gctcaaatgc gcccattttt tgccatgagc catgggattc gaggttcgtt tccgccatca
    18241 catggattcc tgcttggtcg cataaataat accaagtgat ctggttgggg taatgagatg
    18301 tccgtacgcc gttgatcttt gcatttttta tgatagccaa atctttttcc atatcttcta
    18361 tagtgatggc gcgtcctttt ttcggatgcc actcatgtcg atttaccccg ttgataatca
    18421 tccgttttcc attgaagtag atgattttat ctttgatttc gattttacga aaaccgaagg
    18481 aatagtcaat atactccgtt actctttttt cttcgtctat cgtctccaat tcaagcttat
    18541 ataaattggg ctgaaaatgc ccccacagtg ccacattttc aaatccatcg atgcgaatcg
    18601 tcatttgctc ttttaacgga tattgctgtt gatagatttc cttcccatca ggatctagta
    18661 tcgctacatt cagctgactg tttttggcta cttgctcaaa agacaaatct acttcaagtt
    18721 tgccattttg acatttgtca tctaagcgag gtttgatcca aagatcttct aaatggtttt
    18781 gtcctcgagc aactaagaag acatctctga agatcccaaa aaatcggaaa aagtcctgat
    18841 cttccaagaa tgcagctgta cttcttttgt aaacctccac agctagaata ttttcttctt
    18901 ccaaataagg tgttaaatca aattcagacg gagtgaacga atcttcggca tacccgataa
    18961 aatgaccatt caaccaaata aacattgctt gttctacacc agcaaaatga atcgagattt
    19021 gttttccctt tagaccttct tctaatcgaa aagtcgtcaa atacgaacca accggattgt
    19081 ctttagcagc tgaaaagatc ccttccgcct ctttctcagg gcttgtcgtg aaagggggac
    19141 ggcgaaatac atgtccctcc cacggataca tcgtattgat gtaatggatc ttgtcataat
    19201 ttgctaattc aatatgacta ggaacagtga tttcatcaaa agaacaggca tcaaaatctt
    19261 ttttataaaa tgtttttggt cgtaccgaag gatttggcga ataacaaaaa cgccatgatc
    19321 catttaaaga ctgtttaagg gaggatgtgg tttctacttc ttcccttgtt gcataacaaa
    19381 catgatcgct atgtgcattt gattggttca ctctaaaaac ttgtggatca tctaaccatt
    19441 ttatatttgc tttcatactt ttttccttct ctctcataac tttttgaaat gaagcagttc
    19501 tgtttggaaa tcaccttgaa aatcggggaa gtaaagtcca actgtcatca attcggcccc
    19561 cgaaaatatc cgcttcgagg tctgttcctg ataaagtgcc tcatcatcta accccatcag
    19621 atatacttca tggaacgctg gttgagctga agctagtatc ctccctaaaa acacaatagc
    19681 ttcatcttgt ttaggagaca caaacatcca tgcggcaata ttttcttcaa aaggactcgc
    19741 caaacgataa taatggccat actggatcac cggacgaatc gtttgatagg atataatttg
    19801 gtcttttact tgcttttttt cttcaggaga cagctttgtc aaatccagtt cataaccaaa
    19861 aacagcgctc atagctgttt ctcctcttgt tttcaacgaa gtagatctgt cggtctgatg
    19921 atttggtaca gctgatacat gagctgtgat ggacgaaatc ggataagcaa ggcttgttcc
    19981 atattggatt ttcatacgct ccactgcatc cgtgttatca cttgtccatg actgcggcat
    20041 ataataaata aacccggcat caaaccgtcc acctccacca gaacagcctt cccataagat
    20101 ttccggataa tcagttgtca aatgttcaag tagttcataa agcccgagca tataacgatg
    20161 cgctacttct ccttgtctct gtgggtcaag ggtaatcgaa tagacatctg aaagcgaacg
    20221 gttcatatcc catttgatgt agtcaagagg aatcgtatct aaaatctttc tcatttgttt
    20281 ctcaatcgtc tgccgaacat ctaaccttgt aaaatccagt acatgttgtg atctggaagc
    20341 agaaggcatt ctacctggct cctgcataag aaaatcagga tgtgttcgat acagttcaga
    20401 atcaaccgag atcatttcag gttcaaacca taaaccaaat ttcaatcctt tgctatgagc
    20461 ataatctgct atttcacgta atccatttgt caacttgcct tcatactcga accagtctcc
    20521 taatgaagaa ttgtccgcat ctctttttcc aaaccagcca tcatctaata cgaacatttc
    20581 gatgcctagc tcctttgctt catcaatgat cgccttgatt ttttcactat tgaagtcaaa
    20641 gtaagtggct tcccagttat tgaccagaat cggccgttca gcaaattgat gacgacctct
    20701 tgcgattctt tcacgtagca actcatggtg gatctgactc attttgttca atccctgact
    20761 tgagtaagaa aggatcattt caggtgtttg aaaagactgg cctgcattca attcccacga
    20821 aaaacgatgg ctgttgatcc caccgacgac tctcaattga ttgatctgat ctttttcaag
    20881 ttcgaaagaa tggttgccgg aataaacaaa ttgaagtccg atcgcttctc cagtattttc
    20941 tgtcgtatga tgatgaacta aagcaataaa gttattcata tggtgactgc tcgttcctcg
    21001 acggctttca aatacttttg ttccagataa aacagattgc cgtgaaatct gtctttcatt
    21061 gacatgtgct cctggcaaag caatgacttc atcaaatcgc ctagtatggg caaagtctag
    21121 ctggaaacta gccgcttttt ctagtttgat tgtttctccg gtttcatttc ttatctttac
    21181 agatcgtgtg atcactgctc tatcagtaaa tatggtatag aacaaatcga aataaatcgc
    21241 tgtttctcta tccttaagtg aaatcaccaa cgtttgtgcc tctgacttgt ccatcacata
    21301 agtttgaggc aagccttcga tctctggctt cccatctgta atataatggc tgtcatatct
    21361 cagatccagt aagtctgatc cattcttgcg ctgaatgatc gatgcgggcg ttcgaaagtc
    21421 catgctgcca tgagaagagt attcttgcgg tagtgtatct ttcgacagag accggtcagg
    21481 atttaaggga acatttcctg aaaatccacg atctcttcgg ggataatttt tattgtcttt
    21541 gtactgcttg actggtttgc caaaataaat atgcgccaat acattgcttt cttctatctt
    21601 tatcagataa gaaagaaatg tatttcgtaa atggaagact cggctctttt catcaaataa
    21661 gatgaaattt ttatctgttt ttctatgcgt aatatccatc atttcactcc caacaaaacg
    21721 gaaaccgttt acttttttta taattcctgt atactgttta ctaaacaatt ttgtcaataa
    21781 aaatttttta tttttttgag gagtgtgtaa aaatggttgg aattagagat gtcgcacgaa
    21841 aggcaaatgt ctctcctgct acagtttccc gtgtgttgaa taacgatcag acgatccatg
    21901 tggctcagac tactcggcaa cggatagtag aggcagctgc tgcgttggat tatgacatca
    21961 gtactcgtaa atatatcaaa aagagaatgc cttcgattgg tgtgatctct acgatcggca
    22021 aagcgagcga agaacaggat atctattaca aacatttgcg agtagggatg gaagaagaag
    22081 ctcgacgtct gcatttaggg atgaatcgaa tctataatct atctgataat cctaaacaat
    22141 gggaagatct agatcagtta ggtgcggtga tcgttgttgg gactgttacg aaagaatcga
    22201 ttaccgcctt gttaaaacaa aacatgcaaa tagtcgtcgt ggataaccct gacatccagc
    22261 aagaggtcga tatggtgtat gcagatcttg aacggatgac taaaaccgta ctggaattgt
    22321 tcttagaaaa tggtcataaa agaatagcct atatcggggg atataaagtc gatatggatg
    22381 aattcggtgg gaagcagatt tctataaatg aaaagaggat gcgtgcctat cagcatttta
    22441 tgatcgatca tcacttagaa aaatatatgt cttatcatct aggtggctgg acagaaaaac
    22501 aaggtgaggt acttgcgact aatctattag aaaatgaatc ccctcttcct actgccattc
    22561 ttgtcgggag cgatccaatg gcaattggtg tctatcgggc attgaaacaa aaaaatatcc
    22621 aaattggaga agagattgtt gtagcaagct ttgataatat cgagacaatc gcaaacctct
    22681 cccctggctt gaccagtgtt caaatcaatg cgaaatcaat tgggcaagca gctgttcgaa
    22741 tggcattgga gcgaattgac ggtatacggg acgaaccaat cattttgact tatcctgcac
    22801 gattgattgt tagggaaagt tttatcccaa gaacaaaaag gtattgaaag agaggttgtg
    22861 aaaagccgct tcgtttcttc atactcaaaa cgaaacggct ttttcacaac ctcttactta
    22921 tacttattca caaaatccaa tgtctgctgg taacaatttt gcgattcttt tagcgtgtaa
    22981 tcaaattggt attcatgggt aatctctttt tttgtatctg tataaaacaa ggattgcacg
    23041 ggtaccttta attctgtcaa ccgattttct aatgcttgac cttgctcctg gaatgagtat
    23101 gcatttccgt cagttatata cgttggcgga aattccttag aaacatggtc agccacacta
    23161 gcttctttca attgctcact cgttttccaa tcttttgttc caatcaacga ccacgcaacg
    23221 gttttgacga aaaacttcat aaatcgatca tccgaatgct gctgtgctgt tagcttcaaa
    23281 tcaacaggtc cgcaataaga aatggttcct ttcagactat cttttggaag tagctgtttg
    23341 attttcattt gtttagcata cgcatcattc gtttgtatag ctgcatattg caatgcgatt
    23401 tgtgaacctg cactatctcc accaaaaaat aattgttcca tgtctagcaa tttgtcgtct
    23461 ttttcttcag ctaataaatc tttgatcagt tcattcactt gaagaacttg attagggtat
    23521 tctgaatcag gcgctaattc ataattcatc gcaaccactg cgatgttggc gtctgaaact
    23581 aattttgtcg caaattcttt gacacccgat ttatctccgc cgacgaatcc tccaccatgt
    23641 acccaaaata gaacaggaac aggccccttg ctgttttttg gatagtagat gtcataagta
    23701 ttctctttat acttggactc atacgtcaaa tctgtttttt tcgccacgtt tttttctgct
    23761 tgatcgaacg tttttttatc agtgatttga acagtatttg aaaacatatg gttgatcaag
    23821 aatgctccag gtctggggga aagctggaag gcaagaaaga ttgcaaacgc gatcccaaga
    23881 atgattccga agaaccatcc gataaattta agaattttct ttttcataag gctccctcag
    23941 tagttagtat taagcattct gattatacca tagtgttatt tcctatcaag ctctcctaga
    24001 tgatttaatg attttcccca aacttcttct gcaatgcttt tgacaaaaga aattttttcc
    24061 attgttcttc aaacaaaaca ttttcttctt ctgttgaagc aaatccacat tgaggactta
    24121 agcacaaacg atccaaaggc agatatcgtg tcgcttcgta gatccggtca atcacttgct
    24181 ggtgctcttc catttcgcca tttttcgtta cagtcaaaat ctaagacaac taatttatct
    24241 tcagagactt tctctaaaag aacaaaactc ccagcacgtt cactatcgta ttctaaataa
    24301 taggcacgga cattttcttg agtaaaataa tgggtctgct acgtcgtcat cccccctgat
    24361 gccgccaaaa tcgaataata atttccgcgt caaacatgta tatttagtgt tgaatcattt
    24421 gagaatatga aaataaaaat ctttttgatc aatcagttaa tcaaattgaa ataacgaaaa
    24481 atctgagaca gaatgacgtt cattctgacc cagatttgat tttgcacaac tcaacagtcc
    24541 ttattggcaa atcgccaaaa taatgtagac taactaaaa
//
LOCUS       DAZULR010000039        22325 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.039, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000039 DAZULR010000000
VERSION     DAZULR010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22325
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.039"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            5..403
                     /locus_tag="ACG8ZV_001897"
     CDS             5..403
                     /locus_tag="ACG8ZV_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HFS4997211.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            387..1082
                     /locus_tag="ACG8ZV_001898"
     CDS             387..1082
                     /locus_tag="ACG8ZV_001898"
                     /EC_number="4.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HFS4997212.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(1676..2563)
                     /locus_tag="ACG8ZV_001899"
     CDS             complement(1676..2563)
                     /locus_tag="ACG8ZV_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HFS4997213.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            2748..3587
                     /locus_tag="ACG8ZV_001900"
     CDS             2748..3587
                     /locus_tag="ACG8ZV_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HFS4997214.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            3783..4757
                     /gene="sgrA"
                     /locus_tag="ACG8ZV_001901"
     CDS             3783..4757
                     /gene="sgrA"
                     /locus_tag="ACG8ZV_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HFS4997215.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            5055..5411
                     /locus_tag="ACG8ZV_001902"
     CDS             5055..5411
                     /locus_tag="ACG8ZV_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997216.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            5456..6571
                     /locus_tag="ACG8ZV_001903"
     CDS             5456..6571
                     /locus_tag="ACG8ZV_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997217.1"
                     /translation="MKNYHLSCSLKKGNPIEGEEYRIRYFFHLMYWQSFDENHSDILS
                     SIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSITYVPEEMNKFVHPL
                     ITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYLEEDLLDTPDKVQES
                     WGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGTKKKVDAFGKSAEDR
                     DFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCMLVRDIFIKHEQPVIF
                     YIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYPIDKKAYDQTNTQIF
                     YWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6597..7037)
                     /locus_tag="ACG8ZV_001904"
     CDS             complement(6597..7037)
                     /locus_tag="ACG8ZV_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFS4997218.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            7197..7703
                     /locus_tag="ACG8ZV_001905"
     CDS             7197..7703
                     /locus_tag="ACG8ZV_001905"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HFS4997219.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            7871..9783
                     /locus_tag="ACG8ZV_001906"
                     /pseudo
     CDS             7871..9783
                     /locus_tag="ACG8ZV_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
     gene            9788..10789
                     /locus_tag="ACG8ZV_001907"
     CDS             9788..10789
                     /locus_tag="ACG8ZV_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFS4997220.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(10991..11197)
                     /locus_tag="ACG8ZV_001908"
     CDS             complement(10991..11197)
                     /locus_tag="ACG8ZV_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HFS4997221.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(11843..12691)
                     /locus_tag="ACG8ZV_001909"
     CDS             complement(11843..12691)
                     /locus_tag="ACG8ZV_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFS4997222.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            12855..13757
                     /gene="gnd"
                     /locus_tag="ACG8ZV_001910"
     CDS             12855..13757
                     /gene="gnd"
                     /locus_tag="ACG8ZV_001910"
                     /EC_number="1.1.1.343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphogluconate dehydrogenase
                     (NAD(+)-dependent, decarboxylating)"
                     /protein_id="HFS4997223.1"
                     /translation="MEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDI
                     PAYQEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSI
                     RRAEEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLY
                     AGASGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWL
                     MEIMEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEED
                     SFSAKVVSALRNGFGGHEIVEKGE"
     gene            13759..14760
                     /locus_tag="ACG8ZV_001911"
     CDS             13759..14760
                     /locus_tag="ACG8ZV_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-isomer specific 2-hydroxyacid dehydrogenase
                     family protein"
                     /protein_id="HFS4997224.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            14757..15041
                     /locus_tag="ACG8ZV_001912"
     CDS             14757..15041
                     /locus_tag="ACG8ZV_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HFS4997225.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            15074..15871
                     /locus_tag="ACG8ZV_001913"
     CDS             15074..15871
                     /locus_tag="ACG8ZV_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HFS4997226.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNAAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            15885..16718
                     /locus_tag="ACG8ZV_001914"
     CDS             15885..16718
                     /locus_tag="ACG8ZV_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFS4997227.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            16736..17593
                     /locus_tag="ACG8ZV_001915"
     CDS             16736..17593
                     /locus_tag="ACG8ZV_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFS4997228.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLMQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            17615..18124
                     /locus_tag="ACG8ZV_001916"
     CDS             17615..18124
                     /locus_tag="ACG8ZV_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HFS4997229.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            18161..18562
                     /locus_tag="ACG8ZV_001917"
     CDS             18161..18562
                     /locus_tag="ACG8ZV_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997230.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKDIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            18674..19027
                     /locus_tag="ACG8ZV_001918"
     CDS             18674..19027
                     /locus_tag="ACG8ZV_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997231.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            19061..19504
                     /locus_tag="ACG8ZV_001919"
     CDS             19061..19504
                     /locus_tag="ACG8ZV_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFS4997232.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            19521..20606
                     /gene="uxuA"
                     /locus_tag="ACG8ZV_001920"
     CDS             19521..20606
                     /gene="uxuA"
                     /locus_tag="ACG8ZV_001920"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFS4997233.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            20599..21312
                     /locus_tag="ACG8ZV_001921"
     CDS             20599..21312
                     /locus_tag="ACG8ZV_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFS4997234.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            complement(21519..21668)
                     /locus_tag="ACG8ZV_001922"
     CDS             complement(21519..21668)
                     /locus_tag="ACG8ZV_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997235.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            22064..22264
                     /locus_tag="ACG8ZV_001923"
     CDS             22064..22264
                     /locus_tag="ACG8ZV_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFS4997236.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT         7687 a         3430 c         4626 g         6582 t
ORIGIN      
        1 agagatgacg atctttgaaa cggttgtaac agatgttggt atagaagcag aagtattcag
       61 gaaagaaaaa ataatgattt tatttggaga tgaagcaccg gaaacattaa cagattattg
      121 ttataagatt gaattgaatc aggtaagaaa agaaataact tgtgatatga agctctgttt
      181 tgataaacaa atgtatgtaa tcacagcagt aggagatgtt gtccaaacta atttgaatga
      241 attaggacat atcacgataa aatttgatgg atctcatgag ccggaacttc caggaacaat
      301 gtatgtagaa gataaggaaa tgccgcattt aagaaagggg acaatcatta aaatcgatca
      361 agaggatcag aatgggggaa agctatatgg aaatcatgct tgatacagca aatacaaaaa
      421 gtatttattc ttgtcaacag tttttgaatt taacaggcgt aacaacaaat cctacaattc
      481 tgaaaaaaga aggagcgtca aacttcttct cgcatatgaa agaaatcaaa aaaataatcg
      541 gacagattcc tatccatatt cagacaatag gaagaacgga agaagaaatg atagaggatg
      601 ctcgagttat catagaagaa ctgggaaaag atacgtttat caaggtgccg gtgaatcaag
      661 caggccttca agcgatcaaa aagttgaaaa aagaaggtta tttgattacc ggtacagcta
      721 tttacacaga attacaaggg tatttagcta ttaataatgg agcagattat attgcacctt
      781 attataacag gatgcaaaat caaggcattg atgctatgaa agtgattgat tcgttgcgga
      841 ctgagatcga acgtacgcaa agaccaacaa aaatattagc agctagtttc aaaaattgtg
      901 aacaagtcac tacagccatt cgatctggag ctcatgcgat aacgttaggt aaagagctac
      961 tagatcaagt attagagatg ccctcgattg ataaagcagt gaggggcttc caagaagatt
     1021 gggtgcaaac tttccaagca gaaacgattg gtgaactaaa aaaggtcgct gattacttct
     1081 gaatcaattt ctccataaaa taaacgatag ccttctcgaa aactcgagga ggctatctga
     1141 cgattcaata ttcattaatt taaagtttgg gtgactatta ctaactatta cttatttctc
     1201 atttaaacga tgtattccct aacctctaat acatccttgt aactctgaag ttacgccagt
     1261 tttgaataaa tttcataaaa acaaatgaaa agtgtcgcat aaaaatatct ttcgtgtttc
     1321 tctagtataa cagaataaga agaacaagtc cagaagggat atttttagtc ttttttaaaa
     1381 taacttttca gtcgagtttg agtttatgat agttgttttt gaagcgatac ggcaagtgaa
     1441 aaaataggga agcatgaaag aatctactta atggcgcatt gattcatgtg atagaaataa
     1501 aaaacttttt taaattatat cctcatgatt gtaacaaatc cagtgatttg ttttggtaca
     1561 aataaaaaaa ggccccgatg aagttgtggc aaaagtggtt tgcctcaaaa ataagaagga
     1621 atttccaaaa atcacttctc aaattttgcc acatccccaa ttgggtcaaa tttgtttatt
     1681 tgaatatatt ttttacataa ggatctttaa tagttacatt gtcttttttc atcactttac
     1741 ggattgtttt atccatgaat tccgtatcaa gagtttttgc ttcggtagca attttttcta
     1801 gctcagattt gtatttgtct ttattagaac ctttatcctg tttttttacc atttttacta
     1861 gataatagct ttgctgataa gtcgttggat ctgttacagg aatgatatca gaaacttccc
     1921 cgttttttag tttaaatgct gcttttttta cttcagtagg aatctctgga ttggttgaat
     1981 caaaattcat ttttccatca gtttccttta atgttttatt ttttccataa gcttgaacaa
     2041 gcttggagaa attttctcct tcatttgctt ctttttttgc tttatctgct tcttctttag
     2101 tcgaaaatag aatgatctgt gtactaactt ctggatagaa ttctttccaa gcagtgtcta
     2161 gatctttatc tgttaatttt acattggctt tcaaaccgta ttggaaagcc agcatctgtt
     2221 taaagagttt cttatatgtc tcttctgttt ggccaactgc ttttaattgt tccttgtagt
     2281 ttggaccgag ttttttgatt tgttcattat attcttttgt tacttccttt gaagaaatct
     2341 cttttccgta tacatcatca aatgctttga agacaatcat tttttttaat agtgtttgat
     2401 tatttgattt aacttttggg ttatcataaa aatcctgaac tgtaagtgtt ccacctttaa
     2461 acgttgcaat cgtttcattg gacttgctac aacctgagaa tagtaaaatt gcacatgctg
     2521 aaaggcacat aattagtagt tgttttttca aaaaatttcc catcctttcc ttattaaaaa
     2581 cagtctaaca gaagaattag ggagacagtc tttcattttc gtaaggttgc tgtagatatt
     2641 cttagttcgt aaaaatctat tctctctatg atggagaaca tttacatagt tttcacgaga
     2701 caagaaagaa aagggttgtt aaacttaata taaaggaggg atgaaagatg atcaggatta
     2761 ttcggttgat tggatctgtt ttaatagtct tagttggttt tgttttagga attcttgtca
     2821 ataatgcact tgcggatatg tttattggaa atagtgaatg gattggagca attgccggta
     2881 cggtcggaca tttagctgtt tttttactag ctttatttct tgctagtaag gtcgaaggaa
     2941 aaagaataga agattatggt gtttctgttc gaggaaaaga ctgggggtat ttagcgggag
     3001 gtctcgttgt tggaattgga gtgtttctgc ttattactag tccattatat ttgacggggg
     3061 cgtatcggtt agattcagga aacgcaaaca ttgtgccgct gataacgagt tttattttat
     3121 ttattgcagt gggggcatca gaagagcttt tattccgtgg cttttttcag catcagatgc
     3181 ttagatttgg tccgttaata gcaatgattg gatctgctgc attatttgct cttttgcacg
     3241 gattgaatcc taacatgaca tttctggcag ttttcaatat ctttttagca ggttgctttt
     3301 tcagcgcact tatctacagt acaggaagtt tatttacggc tattggtgct catattactt
     3361 ggaattggac acaaggagct attttgggta taccagtcag cggaacgcaa gaacaaggtt
     3421 ttttctccac tctgatccaa tcgcaaaata caataattac tgggggaaac tttggggctg
     3481 aagcatctat atcaactaca ttattcttgt tagtcttgat tgttggtttg ttactctatg
     3541 catataaaac aaagcggatg aagaaataca ctgctgttta tcaataaaag atgaagaaag
     3601 caaggctgat atcggtcttg cttttttaag tctgtcattg attaaacgaa aaagtaaaca
     3661 aattcaagcg aatacacgac atcttttgtt agattttcac aactgactgt cgtgttctca
     3721 tcattttcat tttatataat tcctttatca aatagaaggt aattatatgg agagtgatag
     3781 aaatgaagaa aacagcgacc gtattatttg ttattcttgg gctgagtata attgcagcaa
     3841 tgattggaat cagtacttct gcaaatgaac gggcaaatga gaatctttca tttactgtga
     3901 aaactgatcg gattgtttat gacatgacac aacaagtcat tactattcca gtcaaaccaa
     3961 acaaaagcgt gaatgctagt gatgtacatg ctgttctaac atatggttgg gatggtaatg
     4021 gaagttcaga aaaagttatt ggggaagttt atttaaaaga cgtacaatgg accgctggta
     4081 ttgagtatac aataatgatt tctgcagaac tatcgattga tgagatcaag agtaaagata
     4141 aagttgattt gattgttttt tatgatggac agatgacgat cacggagaat ttgaaaccaa
     4201 gcagttggac agttgttgga ccgccaagca gtacggatag cacaagtagt gaaagcagta
     4261 cagaaaacac gagcggtgaa agcagtacag agagtacgag cagtgaaagt agcacagaaa
     4321 acacgagcag cgaaagcagt acggagagta cgagtagtga aagtagcaca ggaagcacga
     4381 gcagcgaaag cagtacggag agtacgagta gtgaaagtag cacaggaagc atgagtagtg
     4441 agagtagcac aggaagcacg agcagcgaaa gcagcacagg aaaagtaaat aatgaacttg
     4501 atttggtacc tatcatacca actaaggaac aaaagagaaa tgcagggagc aacctaaaaa
     4561 gtgtgctaaa acagcctgat tttgtttctc gtggaattga tcatcaagaa aaagcgaaag
     4621 aaacagataa tagaaaaagc gatttaccag aaactggtag tagaaccttg aacaagctaa
     4681 ttacatggat gggtgtgtta ctcattttga ttgtaggagc aagctatttt cgttctctct
     4741 tccatcgagt gaaataaaga ataaaagcaa cagatctaaa attgaataaa acgatagatt
     4801 tttgagtgaa tatttcattc gagagtgctg tattgcctgg cgaagttgta gctttgccag
     4861 atctattttt gtttactaac atatttgaga aacaggaaat aacaggaaca caaatggaaa
     4921 ataagagcaa gaataattga caatgcacac tgcgcatggt agtatctctg aaaaatcagt
     4981 aacgaatcta tttgtacgtt attcatgtag ctgtcggaat aagtctaaat aatagataaa
     5041 aaggagtatg tactttgttt gaagaattta ttgatatcaa tgaaaggcaa gtatatcaat
     5101 ttttgaacta ttgttatgaa agagacgaga aattatatgt ggtgaaggat atcgctttag
     5161 atctaaacta caccctggct aagatgaatt cggtgattca acaagcagaa tcgttttgcg
     5221 aaaggtatcc agaatataaa ttatcttttc tttcagaaaa caagatgata aaagtcgagt
     5281 tttcttctca gtttttactg agtaaagttt attctatact tttagaggga acgattggtt
     5341 atattttact ggattcactt tacaaaggta cttatcaatc cttagaaaat cttagtcaaa
     5401 aaattatata agtttgcgta cgattcaaag aaaattaaga gaacttaata ctattttgaa
     5461 aaactatcat ttatcttgca gcttgaaaaa aggtaatccg atagaaggag aagaataccg
     5521 tatccgatac ttttttcact tgatgtattg gcagtcattc gacgaaaatc attctgatat
     5581 attatcaagt ataaaaaata aacgtcaact attagaaaaa tttgcgaaac atgcgccata
     5641 tacgcgtagt atagatagaa agaaatggat cagcctacta agaatttcgt tgcaacgaat
     5701 gaaacaaggc cactcgatta cgtatgtccc agaagagatg aacaaatttg tgcatccatt
     5761 gataacaaaa gaagagttta cgcattacat actagagcct ttttttgaag caaacttctg
     5821 gtcgatgaat cacatcactc caacagagca agcttacctt tattttatgt ttggtgtaat
     5881 gaacacctat ttggaagaag atttgttgga tactccagat aaagtacaag aaagttgggg
     5941 ctggattgaa tcgtctattg tagaaaattt tgaaaaaaac ttcaagattt gttttacaac
     6001 ttcagaaaaa aattatctat atgtcaattt ggcaatgatc catttgtatt caagggtttt
     6061 tgggacaaaa aagaaggtgg atgcttttgg aaaatcagca gaagacagag attttcagca
     6121 tatatttcca gtgatgtatc caatcatgca acagtttttt agtggggtag ctcgcagaat
     6181 tccagagctt aatacttatt atgaaaagaa cagacggttg atttttcaat actgtatgtt
     6241 agtcagggat atttttataa aacacgaaca acctgtcata ttctatattc aatcaaagta
     6301 tggtaaaaca caggaattat gggcaaagaa aaggatatta tctatgactg aacgcccaat
     6361 aaaatatagt gcatccgctg atcagttacc tgatattgtc attagcgatt atcctatcga
     6421 caaaaaggca tatgatcaaa cgaatacaca gatattttac tggaatggac aacctacaaa
     6481 aaatgattgg gcgcgtctga aagctgaaat cataaaaatc aggaatgaga aaaatagatc
     6541 catattggaa aaattggatt tcgttaatta agaaaagcag attgtttatg ccaaaattaa
     6601 gacattgcaa aaagattatt ttctttaaaa tcgacaagat gaccagaaag caagagttcg
     6661 ttgagctctt gctttctttt agttttagaa aggaacatcc tgattttatc ttcgctaaat
     6721 ccagtcaaaa gttttgcaga ttggtcgtag ataatcggtt ttttcaataa agaaggggat
     6781 gtacgaatct caatatatag ttcactcaaa ctgagttcat ctattctgtg aacaagattt
     6841 ttataactaa tagaatgagt agagagcatt tcggtcacgc cgttgtttgt caattttagt
     6901 aagtggataa attcattttt ggttagtggt tgacgaatta agttctgttc gataaacggt
     6961 atatcatgga cgataagcca acgttttgcg cgtcttgaag acgagcagcc agaacctgta
     7021 tacaatttaa tcatcataca ttcctccaat agctaagtat ttatgaaata ataacatgaa
     7081 gaaatagtcg aaaagtgcca tttagaggtg taaaataaga aaatgttgtc acgtataatg
     7141 gaactagcta gataagaaat actattaaat caagaaaaaa gaaagaaggc acaagtatgt
     7201 caaacacagc cgacgcaata gtagtgatcg atttacaaaa aggggtatgt tttgattctt
     7261 cgccgataca cgaattagaa acagtgacag cattagtgaa taaaagaatc aaaacatacg
     7321 aaacgattgg gaaaccagtt attttcgttc aacacgaaga tgctcaatta gtgccacaaa
     7381 caaaaccatg ggagctattg tcggaattat ctattcctga gcacagttat tttgtgagaa
     7441 aaacccatgc gaattcattt tataagacta atttgagtgt tttattaact gaattggact
     7501 gtcattcgat cgaattatgt ggggcacaag cagagtattg tatagatacg actgtgaagt
     7561 ttgctcatgg attaggatac cagcttatga tgtgtagagg agcaacgaca acttatgata
     7621 atccttttat gaaagcaaag gaaacaatcg ctttttacga gaaaatttgg gataaacgat
     7681 ttctgacatt tttggagcaa taagttgttt cttcgtttaa aaaaagcaga atggatactg
     7741 gtttatccat tctgctttat tacgtaaaat gagaaaataa tcctgttcta tttttatggg
     7801 ataaaccatt tattttttgt ataaaaaatg tttgcgttta catataattc tcctagaaac
     7861 ataaaaagga gtgaatagct tgagaacaaa acaagtatta aagggagcgt tggtcatctt
     7921 atttgctgta agtacaagcg tcccgcaatg gacagtatat ggagagagca tttcttccga
     7981 atcggaatct cgggaggtag aaaccacaga aactactgat gctggaaatg aaacgaaatc
     8041 gagtacttca caaacagaaa caaatactga aacaacggtt gagacatctg ttactagcac
     8101 agatcaagaa acgaccgcta ccacagataa ccaacaaaca gaagaagcaa cagctacaaa
     8161 aatgtcaaac gacgaatcct cttctgctaa agtaagtgac aaagagaatg ggacagaaaa
     8221 tgatgatatc ggtaaaggtg aaaatttcaa tggtaaagaa tatttgaatt acttcggtaa
     8281 acagatgaca gaaatactta atggaccaac agaagacatc aagtcaaaat taatagagtt
     8341 attagtcact gagcttgctg ttaatgatta tggtgtagat aaagagatta tcaaacatct
     8401 gattgctact tatctattgt acgatatcgc ttttgcaaaa aacagtgtgt tgatgtcgat
     8461 gcttggaggt acagatgatg ggacaacgcc tacagaaaac acaggcttct atccaaatac
     8521 aaaacaactt catcaaactg tactaaacaa acaagatggc aaaatgatgg atgtatatgc
     8581 atattatgtc gatcaaggtt cagataaaac agtcatgatc catggcggat ttcgagggaa
     8641 ttggaataac gggatcgtta cagaagaata caatgatttt tataaggccg ggtataattt
     8701 attatttgtt gattccagag cgactggtaa tagcggaggc gattatgtga cctatggaca
     8761 atatgagtca gatgacgtcc tttactggat aaatcaagaa gttcgagagc ggccatctca
     8821 aaagatttta ctttatggtg gttcgatggg agcagctacg atgatgtctg tattagcgaa
     8881 agatattcct gtcaatgtca aaggaattat tgaaaattgc ggatttgcat caattgatga
     8941 acaactacgt tttacgtaca gccagacagt agcccccgca ctaccggatg ccataaaaaa
     9001 tcagttagac atcattgggg atcaagagca tgaagattta tttatgggcc ttttgaaaca
     9061 atactatttt gatcaggaga tgcatttgga tacaaaagct gctctaccta cgattggaat
     9121 gtcagattca ttgcctaaat tgattatcca tggaacagca gatgatgtag tacctgtgtc
     9181 taacgcgcaa aaattatatg agttatcagg agggtataaa gatcttttat tagtagaagg
     9241 agcagggcat ggaaaggcac aggaagttga ccatgctgcc tacacgaaac atgtaacgga
     9301 ctttttgaaa gtagtgttcc atgatcagat aaacgtaaag tatgtggatg aaaacaataa
     9361 aagtctactc aaagaccagg acgaaatcca gctttacgga gcttatggag aaaattatat
     9421 gacagagcaa aagacattcg aaggatacga attagcaaat gttgaaggac cgactgaagg
     9481 gatttttaat gagacgatac caactattat tttctattac aaaaaaatcc cagtagctcc
     9541 accaaaaaag caagatccga cagagaatgc agacaataag ggaaagaatg aacctcgaga
     9601 ggatcaatca agtgatgata cgcaaccgat tcagatgaca gtgaaagtac aaaaaaagac
     9661 agatgcaaaa aaagaatgtt gccgaaaact ggagaaaaga aacattcgct tctcatttat
     9721 tcaggtggat ttttatctgt tagcacgatt atcacatgga tttggcgaag aaagagaggg
     9781 taaatgaatg aaatggttca agcgaatagt gattgcagta ccagttatca tcgtagttat
     9841 tttagtcact gtatttttga ttaatcaaat cacaccaaag ccgattagct tgcttgttag
     9901 aaaacaattt gacacaagtg aaaaagaaca agtatatgcc cgaccagatg atttccagca
     9961 aaaaatcgaa caaatcgata taaaaaaaga aatatcctat ccttcaaagt acaaaaataa
    10021 taatatggat atctacacac cgaaagtgga aaagaaaaaa ttaccgattc ttttctggat
    10081 gcatggaggc gcatatgtag gaggggataa aaatgattgt cgtgattatt tggaatatct
    10141 atgttcagac acgcagcaaa tcatcgtaaa tatagattat gaacgatcac cggaagcaaa
    10201 acatcctaca ccagttatcc aattgaacga agccattcaa gcagctaaaa aagagataaa
    10261 agatcaagca gattggtcga atatttcgat tggtggaaat tcggcaggtg cacaaattag
    10321 tggagaatat ttgttagcac ttcaaaatga agaaattaaa aaagctgatc atcttgatcc
    10381 gactttggag aacaagcaga ttacgaagtt tatttctttg tctggtctgt tggatccttc
    10441 tgcacttact caagtaagtg ataaaatctc tagctttctt tatgaaaaat gtggatgggc
    10501 ttactttgat aataaggact ttgaacaatc agagaaggtc aaaagtttag ccttggtcag
    10561 acatgcggat cgttggacgc aaaacacatt cttaacggat ggaaatacaa atacgtttac
    10621 gaaacaaatg gaagaagtaa cttctgtatt tgagaaagcg ggggtgaaag tcacaaaagt
    10681 agattatgcg gagaaaaatg ctgttttgaa ccatgaatat cagtttgatt tcagcaataa
    10741 acaagcgcaa gaaacatatc aaaagttagt aatgtttttc aaggagtaaa gtcttatgat
    10801 gcaaaagagg ttgtaatctg tcacttagct ccaagtcaca aggagcaatt tcaataaaca
    10861 agcttttcat ggtttatgaa tattgtaact tgtgactgag gagttagaga tggcaagggg
    10921 caccttttat tcgaaatttg ggaatatcac acgattattg tcacgatctc ttttacgtaa
    10981 attttataag tcagatttgt tgttttgatc gtttaaaaaa agcaacaaat ccgaagcctg
    11041 cggaggcaag aagggacaaa aagccgagtg gtaagcaaaa gaatgctggt tccactaata
    11101 ttccgttgtt attgatataa ggctgggaac aaagatgaat agcaaataaa atcaatgcac
    11161 tagcgaaaaa aagcaaagaa atatggatag ctttcataag cagcacctcc ttttttataa
    11221 ttgtatgata aatagattaa gaatctataa atgtgacaag tttgttagga tgtgaataaa
    11281 atgatcatct agcgaacttg aaacaaagat ggctaatgat aagcaattaa tgattcagca
    11341 atcagatagg tacaaagttt accatcatac gtctagacca ataatagaaa atatgggaat
    11401 ataatagaaa agatttagga tacccccaaa agaatttccc caaaaattcg atgtatccta
    11461 aactttttta ttttacataa caatcatatc aactgtgaaa taaaattaca aatgataacc
    11521 taaaatgagg ccaaaagcca gtgttatcaa ggaaatactt aattcaccaa aatttttttt
    11581 aattttttag aaaataagaa acaaaaataa taaaaaaaag aaaagataaa ttttttacta
    11641 ctgtatacta actttgttat cgcatctaac aagtaactcg aataatacca atacaacctt
    11701 ctccaaagat gcgatgacat acgttctaac ccaccgacta ttgatgttct gtaccaccct
    11761 tgcagaacca aaaaagccac taccaaatat ttggtagtgg ctttttttgt tttatggatt
    11821 tttcgctttt tctgttatgg tgctattctt tgatttcaga aatagtatgt cgaactttag
    11881 cgatagaacg acgtgattct ttttcgttgt aaaacatcaa aatcacatat agagagtcca
    11941 aaatgcttag ttgagaaata cgggaagcta aagcttcaga tcggaattct gtttcttcag
    12001 aaatagaaat aaaaacgaca tcgccaagtt tagcaaggga agaattagct tggctagtaa
    12061 taacgattgt ttttgctcca gtttttctta cggtttcagc aatatggatt gtttcttttg
    12121 attgccctgt gtgagaaatc aaaacagcac agtctttttc cgtcaataaa gaagcttcca
    12181 tcaattgaat atggtaatcc gtgctgtgag aagttgcgat aggggaacgc aaaaatttat
    12241 gataagcgtc agttgctaca atctctgaac cgccaacacc gaaaaaatag acacgtttag
    12301 attcattgat aatagtagcc gcttttttta gatccttttg ttgtaacaac ttttttgtgt
    12361 catttaaagt tgaaatacta gactcgaaca ccttttgcgc catagtgagc tcagtatctg
    12421 ttttctgaat attttcgtgg atagaaatag cagatagatc attttcttgg atcaacatgg
    12481 ccattttaaa atctttaaat ccattataac caagtttttt tgtaaattga aaaaaagtag
    12541 agtcagcaat gcccagttca cttgctaaat tgctaatagg actatgactt actttgcttg
    12601 gattttctaa aatataatcg gcgatagcct gttcttttgg gctgaagtcg ttgtacattg
    12661 ttttgatttg tagtcttatg gagacgctca tgagaattcc tcattttcat aataagatta
    12721 tcattttttc cgttctcatt aatgttaaag atacaaggag agtaggaaaa aatcaaacaa
    12781 aaaatatttt tgtaaaatct atttacaaaa aaattttttt gtataatgag ggtataagaa
    12841 atggaggcgc tatcatggaa attggtgtaa ttggtttggg aaaaatggga ttgaatttag
    12901 ctttaaactt aaaagagcac catcacaaag tacaaggact cgacatttca agtacagctg
    12961 ttagtcaggc aagagaaaat gacattcctg cttatcaaga gatctctgaa tttctagcta
    13021 cttttgagca gaaaaaaatc atctggttaa tgcttcctgc tggagagata accgaaaaca
    13081 tgttaagaaa actttttcca aaactcggac caggagacat tattattgaa ggcggaaact
    13141 cttattataa agattcaatc cgtcgagcag aagagtttca gaaaaatgaa atcggttact
    13201 tggattgtgg gacttctgga ggaatcgaag gagcacgaca tcaagcctgc ttaatgattg
    13261 gaggagataa agaaactttt ctatccgtgg aacaattatt caaagatgta gcaattgaaa
    13321 gaggatatct gtatgctggt gcatccggaa gcggacactt cttgaaaatg atccataatg
    13381 gaatcgaata tggaatgatg caagcaatcg gtgaaggatt ccaacttgta caaaaaagtg
    13441 agtatgcttt tgacttggaa caagtcgcac gtgtttggaa tcatggttcg gtgattcgcg
    13501 gctggctgat ggaaatcatg gaagatcagt taaacgaaca tcccaattta agtaattatc
    13561 ggggaatcgt ttctgcatca ggtgaagcaa aatggacggt tgaaacagcg ctagaaatgg
    13621 ctgttccagt tccagtaatt gcaactagtt tgttcatgag gaatctttca caggaagaag
    13681 atagtttttc agcaaaagta gtttcagcac taagaaatgg gtttggcgga catgaaatag
    13741 ttgaaaaggg tgagtaaaat gccagattat catatagcaa tcgttaattc cagcagtttc
    13801 ggaagagtct ttccacacca cttggaaaga ttaaagtcag ttggagacgt tcatttcttt
    13861 actgttgatc aagagattcc aggaaaagaa ctagcggagt tacttaaagg attcaatatc
    13921 attattgcaa gtgttacgcc attttttcga cgagattttt ttgaaaacaa agatgaactg
    13981 ctattgattt cccgacatgg tattggttac aacaatattg atttaaaagc agcaaaagaa
    14041 caccagacaa tcgtatctat catacctgct ttagttgaac gaaatgctgt agcagaaaat
    14101 aatataacta atttgttgtc catgcttcga cgcacgacac aagcacaagc aagagtcaag
    14161 gacgatcgat gggaagatcg ggcggagttc gtcggtagga cgctgtttaa caaaacagtt
    14221 ggtgtgattg gtgcaggaaa taccggaagc ggagtaatcg aaattttgcg taacggtttt
    14281 cgctgtgatg ttctagctta tgatccttac aaatcagatt tatacatcga aagctttggt
    14341 gcaaaaaaag tagaacttca agaattactg gaacaatcag atatcatttg tttatgtgcg
    14401 aatttgacag aagagaacta tcacatgatt tctgataaag aagtcgatca gatgaaagaa
    14461 aatgtttatc tatctaatag tgcaagaggc gctctagttg atgaagaagc gatgattaat
    14521 ggtctgaaaa gcggaaagat cgcaggatat gccacagatg ttttagaaga agaaccggga
    14581 cgtcaagatc atccgtattt agcgtttgaa caagtagtga ttacgccaca tatatcggcc
    14641 tacacaaggg aatgtttaga agcaatgggt gaaaaatgtg tcagagatgt cgaacagatc
    14701 agtcagcacc ttcttcctga acgttctgtc cagacaaaga gcaactatat aaaaggatga
    14761 tgaagaaaat ggtgaacggt ttaaaagtga aaacaggccc tcaattttat ttatatgaag
    14821 aaggtggtat ttcaaaagtt tctgatctct tgaaatcata cggcgcgaaa agagtactgg
    14881 tcacccacgg aacggtatca tgggaaaagg cgctacctaa attagtattt ttgaatgacg
    14941 aaacgattca atttttttat catcgttatt ctggagaatg tagttatgct gaagccagac
    15001 gaatagctac aatcatcaaa aaaatgaaat cgatttcgta gttggcgttg gcggaggaaa
    15061 actgaccgat ctagtgggtt atagtgccaa tcttgcaaga atcgatttcg gagtcatccc
    15121 tactttagct agtaattgtg ctccatggac acctcttgct gtcatgtata aggagaatgg
    15181 acaagcagaa gggaaaacag aacactttta cagacaagct gcttttttta taacagatcc
    15241 ccaattagtg attgattccc ctgttccata tttcattgcc gggttagcag atacactagc
    15301 aaaatggtat gaatctgagc tcatcttaga acaagatttt ttgcaagatg aatcattttt
    15361 gaagctagca caagatactg cgaagatctg caaagaagag attttgaatc attctgctaa
    15421 agcaatccaa gatatggcac aaagaaaact gacatcggag ttcaaacagc tttcagagat
    15481 tatctttgct gttgctggtt tagttggagg attaggagat aaatacgcaa gaaatgcggc
    15541 agcacatgct atgcatgacg ctatcagtaa atatattccg gaaagccatc gttttctaca
    15601 tggagaaaaa gtagcgtatg ggattttcta tcaactggca ctagaaggtc gctgggaaaa
    15661 aatagacgag ttatatcctt tgtatcggga attagaactg ccggtttctc tagaacaaat
    15721 gggattattt ccgaaagata aacagataat agataaaatg gctgaattta ttgattcgaa
    15781 agagaaagtg catttgattc ctatagaggt aacacagaaa tcactgatac agtcaatgat
    15841 ggaactggaa ggttatatca gaaagatctg aaggaggagg acacatggaa acattaagtg
    15901 tagtacaaag tttgttgatt gctttatggg tagccgcggt tatgtcccgc tggttaggtg
    15961 gaggagccac gttgacctta cgtttttctc ctttgatgac tggattagtc gtcgggttga
    16021 tcatggggga agttgcacaa gcgatgattg ttacagccgc tttgcaaatg atttatatgg
    16081 gggttttttc tccaggagga tcaatgccag ctgaaccatc tattgcagca gctatcgcag
    16141 taccagtcgc attattaggg gatctgtcgc cagaagcagc gattgccgtt gcggtgccag
    16201 tcggattgct cggaagttac ttgtatcagt ttcgtttttt catcaatact tttttaggta
    16261 aatatacaga caaagctgta gaagatttga atacaaaagc tatggcccga tcaattattc
    16321 tttatccaac ggttgcctca tttttattat tcgttccgct tgttttcatt gctttatatt
    16381 taggggcgcc attgatcgct gatgtaatca aagctttaga gggaacagtc gttatccaca
    16441 ttcttgaagt agtaggtgga gggttagcgg caatcggtat cgcgacaact gtatacgtta
    16501 tcggtcgaaa agattatctg gtctttttct tccttgctta ttttatgagt gttgttttga
    16561 aatctttaga tattacgatg gttacttatg ccatttttgg gattattatc gctttgatct
    16621 ttgtccagtc gcaaaaaggg aaacaagtac agcctgccac aagcaataac aattcagcat
    16681 cttttgatga cgaagatgac tatgatgacg gattttaatt taggaggaat gggaaatggc
    16741 tgaaataatg gataatcaaa caggtgctcc tgaagaaatc acgaaaaaag atgtaacaaa
    16801 agcctatctg agatggcatt ttgcaaacga aattcctcac tcttttgaac gttacttggc
    16861 gccatcacta ctatacggaa tgatgccaat cttgaaaaaa ctttataaag atgaagactc
    16921 tttaaaagca gcatataaac ggcagttact gttcttcaac actcaattaa gctggggtgg
    16981 cggtgtgatt actggcctaa tgtcttctat ggaacagcaa agagcagaag aagagtatga
    17041 agaaaaagag atcttgatgc aggatgactt gatgtataac acgaaagcgg gattgatggg
    17101 ggcactagca ggaatcggag atgcaatcga ttcaggaacc gtccaatata tttttatcgc
    17161 aatcgcggta ccttgggcac aacagggaag tcctttaggc gcactttttc cttttatctg
    17221 ctttgggttg tatcaggttt tactaggggt atttttcgca agacaagctt tcactatggg
    17281 ccgtaatgct acaggcctaa tgcaaaacac tggtgttcag acagcgattg aaatgctatc
    17341 agttttaggg ttgtttatga tgggggtgct tgcgggaaac tatgtaaaag tagaatcttc
    17401 attgaaattt gcgatatccg gacgtgagtt tgttatccag gaaattcttg atcaaatcgt
    17461 gccagggata ttacctttag ctgtcgtaat gggtgtgtac ttgttctata cgaaaaaagg
    17521 attgaaagtc acacaagcat tattatggct gactggaata ttaattgtgc tagcaggaat
    17581 cggtatttta taaaaagaag ggaacgtgaa taagatgggt gtagtcaatt tagcgcgtgt
    17641 ggatgagcgt ttgatccatg ggcaagtaat ggtaacgtta tctcaaaaaa gtggagtgaa
    17701 ttccattttt gttgtagacg aagttgtagc aaaagataaa tttatgagag atctttacaa
    17761 aaatgcagga agccgtacag gacaaaaaac aattgtcatt acaccagaga aagctaaatt
    17821 ctattgggat gaatatcaat ttaaagaata caattgtatt ttgatcgcaa aaacagtcca
    17881 aacgatttac gacttagtaa aacacggaat ccccatggaa gaattgaata ttggagggat
    17941 tgctcaaaaa aatcctgata cagatctttt agtgacgaaa tctgtttatt taaataaatc
    18001 agatgctgaa aaattgaaag aaatgaatga acaatatggc gtaaagaata tttattttca
    18061 agccactcca tctgcaccta aaacaggatt aaaagatgta ttgaacaagt ttgatttgtc
    18121 ataaacaaat gcttagaaaa aagataaaga gggcgaaaaa atgaagaaga acgagctgtt
    18181 tcgtgattgg gaatttcgtt atcgctatat ttaccgtaag cgccgtacaa aaaagagtaa
    18241 acagcgtttt ctttcagcat tagtatcaga tatttacagt atgagaacag atgtgacagt
    18301 cattgcttac gatacgctag cctaccgatc aaaagatatt tatgttggag atatcgaaaa
    18361 agcagagaaa gttatctgta cttattacga tacacccgtt catgcattag gaagttattt
    18421 catgtttgat tggaaagacc aaaggaaaaa aacaatctac tctatattat tgtccttcat
    18481 tttgttgttc agtttaggtt ggtggggaat gatgatatat aacaaaaatc ctcatcacgt
    18541 attcgatctg ctatccgtat aaacaggtat cactgtacta gcatttggga gctacttttt
    18601 cttattggga aaagcagctc gcggatggcc tagcagacaa acttttattc gaaatacttc
    18661 atccatatta acgatgctag aaatgatccg tacgattgat gatccgagtg tagcgtatgc
    18721 gtttgttgat gaaggctgtt atggagaaaa gggcttagac agcgtgagat cgggtatgaa
    18781 aaaagaggct attctttttt atctagactc tgttggggca gatacaccgc tacagttttc
    18841 gggaaattat ttttcaaata aagaacagtg gctgaaacaa gttgataagt tgaaagaaaa
    18901 aaacgtcaat tatattttta gtgcaagaaa aaagcaagcg cagttcttct atttgaccaa
    18961 aacagattta cgagggaaaa catttaattg gcaaaatgcc aatcagatta ttgctctttt
    19021 tcgataagta aaaagtgcaa aacaaggagt gagaagacta atgttggaaa tcatgatcgt
    19081 tacacatggt aagttgagcg aaggactgaa agatgcggcg gaagtaattg tcgggacatc
    19141 gagccatatt gaaacaatgt gcttagagtc tggggaggac atccaaacat tcggagagaa
    19201 ggtcaaagaa aaattaacta tgatcaacac agcagaaccc atgctagtat ttgttgatct
    19261 aattagcgca agtccgtaca atcaagcgct cttggcagtc aatgaactga ctgaagaaaa
    19321 gaaagcagcc acttatgtca tagggggcgt gaatctgcca atgttgttag aagcaatcaa
    19381 tcatcagatg cttcacacac cgatagaaga agcggtggaa caaattgtca aacaaggaaa
    19441 agataattta actgtttggc atgcttcagc ggaagaaaaa aaattagatg aggacgattt
    19501 ttagaaggaa ggctgaaaag atgaagtggg gatttagatg gtatggtgaa aaaggggatt
    19561 cgatcccatt aaaatatgtt cgccaaatac cgggaataaa tgggataatt ggaactttgc
    19621 tgactaaaat gcctggagat gtttgggaga tttcagaaat tgaggagttg aaagcatctg
    19681 ttgagagcca aggactggaa ctgcttggaa ttgaaagtgt agcgatccac gatgcaatca
    19741 aggcagggac agatgaacga gattactata ttgataacta tatacgaaca atcaaaaact
    19801 tgtctcgatg tggggttcga ttgatttgtt atagcttcaa accaattttt ggatgggcga
    19861 aaactgattt gtttaatgaa aacaacgatg gaagctattc tcttttatac gatcagaaaa
    19921 tcgtcgatca gatggagcca ggagaaatgt atcaattgat acacagccag tcaaagggat
    19981 tcaaattgcc gggttgggaa gaagaacggt tgaaaaaatt cgctcagctg gaaaaactgt
    20041 atgaaggaat gaccgaagaa gaattatttg aaaatctgac ttatttttta gaaaaagtga
    20101 ttccagtgtg cgaaaaagca gatgtaaaaa tggctatcca tccagatgat ccgccatggg
    20161 aactttttgg ttttcctaga gtgacgaaaa atcttggcga cttgaagaaa attctaaatg
    20221 cagtagattc tccatataat ggactaacgc tgtgcacagg atctttaggg gcaaatccgg
    20281 aaaacgattt agttgaaatc atccatgagg taggttcgcg catccatttt gtccacttca
    20341 gaaacgtgga gtttttagga gaaagaaagt tcaaagaaac ggcacatccc tctacagaag
    20401 gctcccttga tatgtatcat attatgaaag cgttggtgca agaagggttc gacggtccta
    20461 tacgccctga tcatggtaga accgtgtggg gtgaagtggc tatgcctgga tatggcctgt
    20521 atgatcgtgc aatgggactc acttacatgc aaggtctata tgaggcgata agtaaggaaa
    20581 aaccactggg agagcattat gaataaaatc aagctcttca tctttgatat ggatggcctt
    20641 ttattagaaa ctggacgttt agcttatcgt gcttatgtaa aatcagcaca aaagtatgat
    20701 tatgaaatgc gtaaggaagt ctattattta ctaactggcc aaacagaaat ggcgataaga
    20761 gaacaaatgg gcattttgta cggagaagat gttccatata tcaaatggcg agaagcaatc
    20821 aatcaatata aagaaaaaat cgtgaaagaa gataagagag tatatacgaa aaaaggagca
    20881 gaagaaattt tatcttttgc aaaagaaaga ggaatccata caatcgtggc ttcgtctaat
    20941 acacgggtaa aagtagaaat gtatttaaaa atggaaaatc tatatgcctt gtttgatcaa
    21001 atcatttcag gggatgatgt aaaaaaagga aagccggaac cagagatctt tttgaaagct
    21061 tgttcaaaaa tgaatattcc tccaagtgaa gcacttgtat ttgaagactc gattgcaggg
    21121 atcgaagcag caaggcgagc gggcattttg tcttttctca tcaaagatca tttgataggg
    21181 ttgcccgatc ataatgggaa gcataagttg aaagtagatg taagtttata tgaatccaat
    21241 aaagcagact atgaatttta tgacctgcat caagcaaaac gatttttaga aagtaaaggg
    21301 ttgtatctct aataaagagg actattttct agtcctcttt atttattgtc ctgcacgact
    21361 gagggaacag atgaaaaaga agtaattttt tattttgaag tatctacctt atttgtagtg
    21421 aacaatttag aacaaacaca aaacgcatct actgttatct accagtagat gcgtttaaag
    21481 agaagaacga gaatcgtcca tatgagggtt tccactcctt atgcagattt ttttaattct
    21541 tgcactgctt gttcgatcgt aacacctgtc gctacatgat tggtattttc tttgtcaaaa
    21601 acgacaaata gattcaaatc tgtatccaag gttactcgat attgtatatc tttgttatag
    21661 aatgtcatag ccattctcct ttctttaaat acttgctgaa aggcaacgaa cgcgttgata
    21721 acgaaattcc atttataagt ataccaccaa ttgaaaggtt ttcatagtta agaaatttta
    21781 aagtcaaaag ttgcagataa aagcaaataa acaagaaaac aaaaagtgaa tcaatcgcgg
    21841 ttattcaact ttttcttcga ttcgaagaca atagaagaca atgaatttta tatttcattg
    21901 cattatcctt gtgttattag aaaaagcatg atatattaaa tgagtaatct attttgaaac
    21961 gtaatttgag cgatatatct acatagataa aactcctttt gcctatcaaa tatttattgc
    22021 aacgaaaaaa cgtacattga tacgtatcag gaggaattta tttatgaata acggtacagt
    22081 aaaatggttc aacgcagaca aaggttttgg ctttatcact ggtgaagatg gaaatgatgt
    22141 atttgcacat ttttcagcta tccaaggtga cggcttcaaa actttagaag aaggccaagc
    22201 agtgtcttac gatgttgaag atggtcaacg tggccctcaa gcaacaaaca ttgttaaagc
    22261 ttaataaaaa ttgactttta accgtctttt cgaaagaaaa gacggttttt ttgtacgaaa
    22321 aaatt
//
LOCUS       DAZULR010000040        22234 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.040, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000040 DAZULR010000000
VERSION     DAZULR010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22234)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22234)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22234
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.040"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            304..2139
                     /gene="tdc"
                     /locus_tag="ACG8ZV_001924"
     CDS             304..2139
                     /gene="tdc"
                     /locus_tag="ACG8ZV_001924"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HFS4997237.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            2444..3922
                     /locus_tag="ACG8ZV_001925"
     CDS             2444..3922
                     /locus_tag="ACG8ZV_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFS4997238.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            3888..5219
                     /locus_tag="ACG8ZV_001926"
     CDS             3888..5219
                     /locus_tag="ACG8ZV_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFS4997239.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            5333..7885
                     /locus_tag="ACG8ZV_001927"
     CDS             5333..7885
                     /locus_tag="ACG8ZV_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HFS4997240.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(7892..9331)
                     /locus_tag="ACG8ZV_001928"
     CDS             complement(7892..9331)
                     /locus_tag="ACG8ZV_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4997241.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            9306..9488
                     /locus_tag="ACG8ZV_001929"
     CDS             9306..9488
                     /locus_tag="ACG8ZV_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997242.1"
                     /translation="MIFFISEYINQTPFYSKNTEKINGGQVSTDFSIIVYFSGAFTDD
                     KNFIMNLKNDTTKIKK"
     gene            9677..10039
                     /locus_tag="ACG8ZV_001930"
     CDS             9677..10039
                     /locus_tag="ACG8ZV_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HFS4997243.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            complement(10226..11083)
                     /locus_tag="ACG8ZV_001931"
     CDS             complement(10226..11083)
                     /locus_tag="ACG8ZV_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFS4997244.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            11203..12114
                     /locus_tag="ACG8ZV_001932"
     CDS             11203..12114
                     /locus_tag="ACG8ZV_001932"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HFS4997245.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            12121..13767
                     /gene="mdcA"
                     /locus_tag="ACG8ZV_001933"
     CDS             12121..13767
                     /gene="mdcA"
                     /locus_tag="ACG8ZV_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015451 - decarboxylation-driven active
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HFS4997246.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            13869..14168
                     /locus_tag="ACG8ZV_001934"
     CDS             13869..14168
                     /locus_tag="ACG8ZV_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HFS4997247.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            14158..15834
                     /gene="mdcD"
                     /locus_tag="ACG8ZV_001935"
     CDS             14158..15834
                     /gene="mdcD"
                     /locus_tag="ACG8ZV_001935"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HFS4997248.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            15838..16431
                     /locus_tag="ACG8ZV_001936"
     CDS             15838..16431
                     /locus_tag="ACG8ZV_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HFS4997249.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            16455..17531
                     /locus_tag="ACG8ZV_001937"
     CDS             16455..17531
                     /locus_tag="ACG8ZV_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFS4997250.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            17556..18425
                     /gene="mdcB"
                     /locus_tag="ACG8ZV_001938"
     CDS             17556..18425
                     /gene="mdcB"
                     /locus_tag="ACG8ZV_001938"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046917 - triphosphoribosyl-dephospho-CoA
                     synthase activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA];
                     GO_process: GO:0019361 -
                     2'-(5''-triphosphoribosyl)-3'-dephospho-CoA biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HFS4997251.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            18536..19300
                     /locus_tag="ACG8ZV_001939"
     CDS             18536..19300
                     /locus_tag="ACG8ZV_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HFS4997252.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            19789..21882
                     /locus_tag="ACG8ZV_001940"
     CDS             19789..21882
                     /locus_tag="ACG8ZV_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFS4997253.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            21907..22209
                     /locus_tag="ACG8ZV_001941"
     CDS             21907..22209
                     /locus_tag="ACG8ZV_001941"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFS4997254.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
BASE COUNT         7206 a         3791 c         4733 g         6504 t
ORIGIN      
        1 gcgaattttt aacaatataa aaaaataaaa atatgtttag tgaatgaagg acagtcattt
       61 tatttgtttg ttcgcttttt ttaggttatc tattttagaa gactgattta ttgaaaaatt
      121 gttcgctttt ttgcgttgaa ttatcagaaa aatccgactt tatttatttt tgtttgtaaa
      181 aatctacgtg gatttgatgt tataaaaaaa aaattctcat ttttggcgct atagtgaaga
      241 ggtgttacag ataaacacat gtatctgcaa gacattgacc aacaaaatat ggagggaaga
      301 aaaatgaaag atatggatat caaggccgtc tttataggcg acaaagctga aaatggacca
      361 gtttataaaa tgttgttgaa caagatggta gatgaacatc ttggatggag agaaaattat
      421 attccttcag atatgcctgc aattagcgaa ggagataagc tcactccaga ttatctagcc
      481 acccgcgacc atatgataga ggtcttggat gaagtcagtc agcgattacg cgcaggatcg
      541 atcccatggc attcagcagg ccgttactgg ggacaaatga atgctgaaac attgatgcct
      601 gctttattag cttacaacta tgcgatgctg tggaacccaa ataatgttgc attggaatct
      661 tctatggcaa cttcgcaaat ggaagcagaa gtaggacagg attttgcttc attattcaat
      721 atgacagacg gatggggaca cattgcagca gatggttcta ttgctaatct tgaaggatta
      781 tggtacgccc gttgcatcaa atcgattcct ttagctgtca aggaagtgct gcctgaaaaa
      841 gtgaaaaaaa tgtctgagtg ggaacttttg aatttatctg ttgaagaaat tttggaaatg
      901 accgaaagct ttacggacga agaaatggat gaggtcaaag cagcttcttc ccgtagcgga
      961 aaaaatatcc aaagattagg gaaatggctg gtccctcaaa caaaacacta ttcttggatg
     1021 aaggcgttag atatttgcgg agtcggctta gatcagatgg ttgctatccc agttcaagag
     1081 gattatcgaa tggatattaa tgctttggaa aaaacaattc gtgaattagc tggacaaaaa
     1141 atcccaattc taggtgtggt tgctgtcgta ggaacgacag aagaaggtca agtagacagt
     1201 gtagataaaa tcgtccaatt aagagaaagg ttaaaagatg aagggatcta tttctattta
     1261 catgttgatg ccgcatatgg cggctatgcg cgttcactgt ttctaaacga agcaggagaa
     1321 tttgtgccgt atgcttcctt agctgaattc tttgaagaac atcatgtttt ccaccactgc
     1381 gtaacgattg acaaagaggt atatgaaggg ttcagagcta tttcagaagc ggattctgtc
     1441 acgatagatc ctcataagat gggctatgtc ccttatgctg ctggaggaat cgtaatcaaa
     1501 cataaaaata tgagaaatat catttcttat ttcgcgccat atgtgtttga aaaatcagta
     1561 aaggctccag atatgttagg agcttatatt ttggaaggat caaaagctgg agcaaccgcc
     1621 gccgcagtct ggacagcaca tcgtgtattg ccattgaatg tgaccggata tggtcaattg
     1681 attggggctt caatcgaggc agctcaaaga ttcagagaat ttctcgatca tctgactttt
     1741 actgttaaag gaaaaacaat cgaagtctat ccattgaatc atcctgattt taatatggtc
     1801 aattgggtat tcaaagaaca aggctgtaca gatttgaacg ctatcaatga attaaatgaa
     1861 aaaatgttcg atcggtcttc ttatatggat ggcgatgttt atggtgaacg gtttattact
     1921 tctcatacta catttacaca agaagattac ggtgattctc cgattcgttt tgttgaaaga
     1981 atgggtctaa cgaaagaaga atggaaaaaa gaacagaaaa tcactctgct acgtgcggct
     2041 atcatgactc cttatttgaa tgatgatcga attttcaatt tttatacaaa aaaaatcgcc
     2101 aaagcaatgg aaaagaaact aaacgaaatc atccaataga actgattttt gtgtgaaaga
     2161 ataacaagag acatatggag aacagacaat tatttgcttc atcaaaacaa ttgtatttcc
     2221 ccctgttttt catatattcc tcgccaagat attctttttt ataaaacgtt ctataagttg
     2281 gatcgttcgt ttcatgtatc aaacccagtt cactaagatc gttcaatgga tgtttcggtg
     2341 atactgggtt ttgtactgaa tcgatgaaac cttgtcattt ctgttcttga acaaaaataa
     2401 aagaaaacaa aaacatatgt cgctattgaa agaaggaata aagatgaaag atactggttc
     2461 atcaaagcaa atcacgacca tgacctttat cggaatgacc tgcgcccttg tagcaagtgt
     2521 acgaaatatt ccagatgtag cagcaacgag ctggacgatg attttttaca tgctggttgc
     2581 agtattattg tacgcttttc caatctcatt gatctctggt gaatttgctg gaatgtttcc
     2641 ccaaaaaggt ggtccagaac tttgggtatc gaatgctcta ggaaaaaaat gggggttcgt
     2701 tgtctcatgg ctgttatggg tccaaatgtt tcctgggatg gtgatggtcg cttcagcact
     2761 cgctccgttg tttggtaata ttatcgataa tgtgccgctt ggtttgaaca gcaaatttac
     2821 attagttgtc attttagtcg tttattggat catcactttt ttgaatttga aatttgatat
     2881 ggcaaaaatc ggcggaaaag tcggtgtttg gttaggattg tacgtgcctt tgacgatgat
     2941 gctcttatta gggtttgctg cgtggatcaa agttgggatc gtaccaaccg gaacattagg
     3001 cagtttttca tgggacaaat taataccaga tactacgact gcatcctcat ttgtttattt
     3061 tgcgccgatc atgtttattt ttactggtat cgaaatgtcc tctgtgtata tcactcgatt
     3121 ggaaaatcca gttaaaacgt atattcgcgg agtatttgcc gcgttaattt ttatattttt
     3181 cgtcaatatt ttgaatgctt tagttgtagc aaatgtcgta ccaaaaggac aaatggaatt
     3241 gaataatatc gcgcaatcta tttcgattta ttgccaaatt cttggtttgc cacatcttat
     3301 tgtgaatctg tttagtttac ttgtcttcat tggtgtagca gtccaattat ctgcttgggc
     3361 ctcaggacca gcaaagacag tgacagaaag tgctagaaaa ggtgcgtatc caccaaaatt
     3421 caatttttgg aagacgaatc aatttgacgt atccaaatcc gttattttga ctcagtctgt
     3481 cattatctca atctttgcac ttttttattt gctgattcct ggcgtcaatc aagcattttt
     3541 gatgctcgta aattcaacta ctgttatcta ctgtatcgtc tatgtcatca tggggatcgc
     3601 agttttgaga ttgcgttata cacatgcaaa gttgaatcga ccatttagaa ttggaaaaaa
     3661 agagaaaaag agcaatcttg gagtttggac tgtcgttatt gttttatttg cggcaatcgg
     3721 attttctgtc ggactgacga tgaaagctgg aacatggatc aatctaattg cagtcacagc
     3781 catcagtgtc attttgtttg tagtaccact ctgtattgaa aaaataaaga aaccttcttg
     3841 ggaacaggaa gtcgccatgc tgcttgaaaa agaaaaaggt gaacttgatg gaaaaaccgg
     3901 caatgaaacg gactctaact aatcgaaata tccagttaat cgcattaggt ggcgcaattg
     3961 gaacaggatt atttttaggt tcagcaaagg caattgcatc agcagggcca gctgttattc
     4021 tcgtttattt gatatgcggt ttggctattt atggtttgat gcgggccatg ggtgatttat
     4081 ttttagcaaa tagtacattt aactctatca gtgatttcgt tgactattat ttaggcaaaa
     4141 agtgggcatt ttttgtcaat tggacttatt ggctttgctg gcttggagct ggacttgcgg
     4201 aattaacagc aataggattg tatatccatt tctggtttgt acatgtacca gctttgataa
     4261 gcggaggtag cgcactaatg atcttaatgg cagtcaacct tgttgcagtc aagtggtttg
     4321 gtgaattgga atcttttttc tcaatcatca agatcttggg gattttcctt tttatcttat
     4381 tgggtatagg attgagtgtc tcagattttc atacccagtc tatcggaatc aaagaaaatt
     4441 ttggacagat cgatgaatta ctaccgtttg gctttgctgg aatggtagtc tcatttccta
     4501 tggttttatt cagttttgct ggaattgaaa tgatcggctt aaccgttggc gagacaagtg
     4561 atccgcaaaa gaatttgaaa aaagcaatca actgtctgcc ttggcgtatt ctctttttct
     4621 atataggaac gattttgtcg attttatttg ttgttccatg gcattgttta gatttaaaag
     4681 aaagtccttt agtgactatg ctgcaagtga tccattgcca aggcggagca gcaattgtca
     4741 atctaatgat tttggttgct tctttgtcct cagcaaatag tgcagtctac agtactagca
     4801 ggattttata tcaaacagca aaagaaaaaa gtttgcccca ttggttttgt gcgctttcta
     4861 agaaaggcgt acctttacac ggtattttaa ttacaggaat gttatttttt gccggtcttt
     4921 gtctacattt ttttgtagct gatagtcgat tgttttttca gcttttggca ggcatgacaa
     4981 cgagttgttt tctatttgtg tggtcttcga tcttgtgtgc acatgttcaa tttattaaag
     5041 aaaagaaacg gaacactaca caaagatata aagatcttgc tttgttggtg ttttttactt
     5101 caattgcttt cagcttgtta ttcgaaagca cgacacgctt tattcctttt ttattggtta
     5161 tctggtttgt attcttaaat tttgtatata aaagaataag caatagaaat atcagttagg
     5221 cccagataca ttttgcaaaa cgaattattt cagacccccc tgaaataatc gatacgcctg
     5281 aaaaaacttc cctgcgtata ataacagtat caattaaaca ggaggggata ggatgaactg
     5341 gtacagattg acggtagaag atgtattgaa aaactatcaa acatcaacag aaggcttgtc
     5401 gcaagaagaa cgacagaaac gcctgactga tcaaggatat aatgaaataa aagcaaggca
     5461 gcagacaaaa cgatggaaaa aaatagcaaa gcattttact gatctgctga tgatcgtgtt
     5521 gatcattgcc tcttttttga aatttgcttc tagtgaatat attgaaggaa gtattatttt
     5581 attcgtagtg atcgtcaatg gactcgttag ttactggcaa gaaagaaaag cggaagaatc
     5641 attgaatggt ttgaagcagc tgatgggaca agaagcgata gtactatcaa acgggatgca
     5701 agaaaaaatc cctgcgaaag aactggtaaa aggagatgtc attgtcttac gtgccggaga
     5761 tgtcgttcca gcagatatcc gattaatcga agcacatgat ttattagtgg aagaatcgat
     5821 tttgacggga gaatcagaag catctgaaaa aagtcatgcc gttttgacag aagaagaatc
     5881 gatcggcgac cagaaaaata tgggtttttc aggaacgctt gtacaatctg gttctgcagt
     5941 cggtgtcgtt gtagaaacag gaaacacgac agaaatcggt aaaatcaatc aagcattgca
     6001 atcggtcgaa caacaaacga cgcctctgat taaaaaaatc aaccgattaa acaaacaaat
     6061 ttttcaaggc attctttgtt tgagcctatt cttagttatt tttacgacat ttcgatatgg
     6121 tatggattgg catatccttc tttcggctac gattgctttg gtggtgtcaa tggtacccga
     6181 aggattgcca gctgttttga ccatgattct atccgttgga gtacatgaaa tggcaaaaga
     6241 aaaggcgatc atcaaaggac ttccttcggt agaaacatta ggttctatga cagtgatctg
     6301 ttcagataag acaggaacat tgacaaaaaa tgaaatgaca gttgtggatg tagctgcaaa
     6361 agaagaagcc tgcgtgttgt ccattatgaa aaactgtcag gaattaaaaa caaaagaaga
     6421 acagaaaaca gaaaatttaa gtggcaatcc gacagaagtt gcgctgattc gacacacaga
     6481 aacagccaat ctacctttga aaaaaataga agcaaagatt ccgttcagtt ctgaatacaa
     6541 atatatggca acgatgcatg cggaggaaaa aggagcggtg atttacgtca aaggtgcacc
     6601 agaagtatta tttgctaaat caactctttc ttctgcagaa caagaagcat ggagtcagac
     6661 agctgcagaa tttgcgagaa aaggtcagcg tgttttagga tttgcttata aaaaagtaga
     6721 ttcgaaacag gaactcacgc atgagacttt aacccaatta acttttgcag ggatcgccgg
     6781 attgatcgat ccgccaaaag aaagtgcagt caaagctgta aaggaatgcc aacaagcagg
     6841 gatctcagtg aaaatgatta caggggatca caaagacaca gcaaaagcga ttgcggaaca
     6901 aattggctta aaacatactg ccaaagtttt agaagggatc gatttggatc ttatgtctga
     6961 tgaagagttg attcagcaag tgccaatagt cgatgtcttt gctcgaacga caccagaaca
     7021 taaactgcga attgttaaag ctttgcagaa aaatggagaa atcgtcggaa tgaccggaga
     7081 cggcgtaaat gatgcacctg ctttgaaaag atccgatgta ggaattgcta tgggaatcaa
     7141 aggtagtgaa gtaagcaaac aggcagctga tatggtttta ggagatgata atttccatac
     7201 gattgcaaaa gccgtaaaag agggccggcg gattttggat aatttgcaaa aaaccatcaa
     7261 tttcttcttg ccaactgcat tagctcaagg attgatcttg atttgggcac ttatgctgaa
     7321 tcgcccgcta cctttgtccc cagtacagat tttatgggtc aatatggtaa cgacaatcac
     7381 tttatcttat gcactagggt tcgagtcgcc agatccagaa atcatgaagc gcccaccaag
     7441 agatccaaag caaggaatcc tatctggtta tcatttgttt cggatcatct atgtctccct
     7501 actgatcatg gttcctgcct atttattggc tatgcagttt gaagggcaaa gcttacagca
     7561 aaccattctt ctgcaaaata tcgtcttagc tcaagctgtt tacatgatca attgcagaga
     7621 gttgtccaag ccgtcattga accaaggtct tttgcaaaac aaagcgcttt ttctttcatt
     7681 aggtatcctt gctttattgc aagggatggt tatttttcta ccagtcggcc agcagctgat
     7741 cggtacagta agtttaacga tgacacaaca gttattgatt ggagcaaatg tgattcttct
     7801 attcttagtt gtagaaatag aaaaagggat catgaacaaa ctgtttcgca aaaaagaaaa
     7861 aacagctaga gaatacagtc gctagccgtt actataaaaa agttttgaaa gtgagttcag
     7921 tcaaacgatt gagctcattt ttcgttggaa tagaagaaat gtatacaata gggatatcta
     7981 gagaatctag agggaaattg gaaatcaaga tatctgtttt ttcaaaagaa atagtggaaa
     8041 gatcggttag ttcgataggt aagaagcaga cacgttttcc taagtaatct tttaattcct
     8101 gctgcaagaa cgccttccat gaaggttctc cttggaaaat aaaatagaca ttgaacaaat
     8161 tcggtttgat agaaaaaatc gtttgttgga tcagtagaga caagagttgg agaaagtaat
     8221 ttggttcatt gatttctatt tcttttttta gatcgttcag taaattctct ttctgttgat
     8281 acaagtgtgc atattgctga tcatatgttt ctaaaaaacg atggtattga cggtccaatg
     8341 cttcaatcaa tatcggcgat tcatgatatt ttaatatgag gagagccaag ttatcagtca
     8401 gagatgtttt ttttagttga tcaagagaca gctctgaagc tagttcctct acaaacgttt
     8461 cgaggacctc taaaaatgga gaatgatgca ggcagcgagc ggtttcttgt ccatagttat
     8521 tgttgtaatt ccaactttcc agaaagcaga aagaagcaaa agaaagctca gtgtctttaa
     8581 gataaatacc ttccgttaaa tacaattttt tcaatgcaga gtcatacagg gaggagagtg
     8641 tgctgttggt atggatagaa gaatctaatc ggcaattcgc ttttatacgg atcgtattga
     8701 taaagaacca acatgttccg aaaatctctt ctgtttcaac cgctagttca gtttgactga
     8761 ggtttcttaa aaattgaaaa taatgggatt catggatcga ataatcctcg aaaaaatagt
     8821 tgttatgagt gaaaggaatc agcaatcgat gataaaaagt acgaatcgca cgctcttttc
     8881 caagaataca agctgtatat ttcgtcaaat cgatctgcaa gtcgtaactt gctaaacgct
     8941 gattgatttt agtcacatgt cttttcaatg tcccataaga aagcccatgg tcggctagaa
     9001 aatcagggac agcaactttt tttgtaaaaa gcagattttt cagcagttcg acactgactg
     9061 attgtttgaa aaaaatctcc caaaggtcat ttgttaataa attttgctgg ttttgcaaac
     9121 tgattcctgc ttgatcgctg atgatgtccc agccttcggg cagctgagag cgaatagatt
     9181 gaaggtcaga aaaaatcgtt cgttcggttg tccctatgat ttcagctaat tcatttacgg
     9241 ttatctttgt atgattcagc aattgttcta ctaaagaaac atgacgtcga atatcttttt
     9301 cggtaatgat ttttttcatt agtgaataca tcaatcagac tcccttctat tctaagaata
     9361 cggagaaaat aaacggtggt caagtttcaa ctgatttttc aatcattgtt tatttttctg
     9421 gagcatttac tgatgataag aatttcatca tgaacttgaa aaatgatacc actaaaatca
     9481 aaaaataggt gggcaaacaa taataaacat tttaatagta gatggtagca agaccaacac
     9541 aggcggattg aacatttaag agttgataaa aaagaaaaat atcgaagtat ttgattagca
     9601 actacttgta ttcatttttc tattcttacg tggtatcttt gaataaagcg aatcaataag
     9661 aaagagatgg aagcagatgc taacgaaaaa agaactaatc gatcacatca atgaaacata
     9721 caatttgtct ccagaatata tttttaaaaa atttcctgat tattgcgtat tcagacatca
     9781 aaaaagcaaa aaatggtttg gggtcctgat gtctgttcca gaagaaaaaa tctatgatga
     9841 tgcaagtgac cataggatca tcaatattct tgatttgaag gtcgatcctg aacttggcgg
     9901 aattttgcga ggaaaagagg ggtattttcc agcctatcac atgaataaag aacattggat
     9961 ctctattgat ctacgtaaaa tagaaaagct agatgaacta gcagatttga ttgatggaag
    10021 ttttaaatca acgcaatgaa tgtctaggac aatagagaag aggttgtgac agaaatgttt
    10081 agcttcaaga aataagaagg aatttacgaa aattgcttct caaatttttg ggaaatttcg
    10141 gcttattttc taagaaatta cttctggaac accgtttgtt cgaaaaaaga gctgcgacaa
    10201 gaattttgtc ccagctcttt tttttttatt ttcctaaata aaattcccgc atcgtttttg
    10261 caatcatttt gatcaaagga tgatcttctg tgaagctaga agataaataa attgttcgtg
    10321 tcaagggcaa atctttgatt tcccgcaaga cgaaaggatc atttttatcg taagaccaag
    10381 aaacttttgg gaaaaagcta acagctaatc cttgcttgac aatagaacgt aatgtcgcag
    10441 gatcatctgt cgtcgaactg atcgtcaatt cgatactttt cgcttcaagt gctgcatcca
    10501 gtgtatgacg gaaggcgttg ctctttgaca gcatcaagat gggggtgcgt tggatatctt
    10561 ctaattgcag atgttctttt ttagcaagag gatgtttctt aggaatggcg acataaacag
    10621 gttctttcat gataggaata ttggtcatgc caggcttcat ctccgaagtg atgtacagta
    10681 caggatcggt aatatcatct ggtaaatgat gttgcatgat cgttaattgg atatcaggat
    10741 gcttttccat aaaaattcgg accaagttcg gaatagaaac agaggctacc tctaaataca
    10801 atatgacgga agtaacgatc ttctcattga ccgaagacaa taatttgatt ccttcttcta
    10861 atgtgtctaa tgtcttgact gcatatggat aaaattcttc tgcataaacg gtcgtctcaa
    10921 tgtttctgcc gctatggtaa aacaaaggga cacctaattc gttttccaaa tgtttgatcg
    10981 cacggctcaa ggcaggttga gaaataaata attctttggc tgcttgggta acattttttg
    11041 tttcgaatac ttttttaaaa tactgcagat gaagcaattt cataattatc catcccatcc
    11101 ataccttttt gttatggttt tttctttttt tggcattttt tattatagca gaaattgact
    11161 aagatagcag tggaaaaagt aagtgctgag gaggcgaggc tcatgagtac aggtttctta
    11221 tttcctggac aaggcagtca gaagttaggg atgttagcgg atatccctga aatgtacatg
    11281 gaacgtttag aaaatgtgac ggggtatcgg ttagttgata aagaagaaaa ctatcaagat
    11341 acggttttta tccagctagc attactgaca aaagcagtat tttatttaga tgaaatggaa
    11401 aaaaacggta ttcagcctga tattgcagca ggacattcga ttggtgcttt ttgtgcagct
    11461 gttgcttgtc gatctttgag atttgagaat gcagcggaac tagtctatca ccgcgcagtc
    11521 ttaatgaaag aagcttatcc aagcggttat gcaatgggcg tagtagtagg tgtgacgaga
    11581 agcgaagctg aggaaattgt agcaaaaaca tttgatcctg accatccagt ttatctgtca
    11641 aatgaaaatt gtccgatgca acatacgtta tctgggagta tcgaaggttt atccgttacg
    11701 ttggcagaag ccaaacggca ccaagcgcaa acagcgaagc tgctgaaagt ccctgtgcca
    11761 tctcactgtc tcttgatgaa tgatacggtc aagaaattca agccgtatat gcagtctgtc
    11821 catctatctg atgctagatg tttgtatata aaaaatacgg atggaagagc cactcaggac
    11881 gcagaagaga ttcgtaaaga tttgttggaa aacctagctt tccctgtgca gtggaaccaa
    11941 atgatggact tggcaaaaga attaggaatg gatctgacga ttgaatttcc ccccggcaat
    12001 actttgacaa agctgattca tacaaaattt ggtgtagata aagggatccg tacgatcaat
    12061 ctagaccaac atggtattga tgacgccacg tttctatatc aaaaatggag atgactaatt
    12121 atggaaaaac caaaccgcaa ctgggcttct aaacgcgaaa aaaaagcgca gcgattggaa
    12181 aaaatcagca acttgctcaa tggcaagtat gtagaaactg aaaaaatcgt agaagtaatg
    12241 gaaaaactga ttgctcccgg cgacaaagtt gtattagaag gcgacaatca aaaacaagca
    12301 agttttcttt cagaaagtct tgaaaaagta gatgcagaaa aagtgaatga tctgcatttg
    12361 atcatgtcta gtatctcacg accagaacat ttgaatattt ttgaaaaagg aatcgcaagc
    12421 aagatcgatt tctcttatgc tggtgcacaa agcttgcgtg tcgcccaaat gattgaagac
    12481 ggcacaatga aattaggtga tatccatact tatttggaac tttatggacg cttattcatc
    12541 gatttgattc caaatgttgt tttagtagct gcagataaag cagataaaga cggcaacttg
    12601 tacacaggtt tcaatacgga agaaacacca acaatcatcg aagctgcagc tttcaaagat
    12661 ggtatcgtga tcgttcaagt taacgaagtt gtcgattctt taccacgtgt agatatccct
    12721 ggtgactggg tagacgttgt cgtgaaagca gataaacctt atcaattaga agctttattc
    12781 acacgagatc ctcaaaacat cacagaattg caaattctaa tggcaatgat ggcaatcaaa
    12841 ggaatctacg cagaacacgg cgtacaatct ttgaatcacg gtattggatt caatacagca
    12901 gctatcgaat tgttactgcc aacttatggt gaatcactag ggttaaaagg gaaaatcgcg
    12961 aagaactggg tattgaaccc acatccaacg atgattccag ccatcgaatc aggttgggtt
    13021 gaaagcatcc atagttttgg tggcgaagtt ggtatggaaa aatatattgc tgctcgccca
    13081 gatgtctttt ttgtcggtaa agacggcacg atgcgcagta accgaacatt atcacaagct
    13141 gcaggacaat atgccatcga tatgtttatc ggttcaacct tgcaattaga ttacgaagga
    13201 aactcttcta ccgtaacaaa aggacgttta tctggttttg gcggtgcgcc taacatggga
    13261 cataatcctg gcggtcgtcg tcattctaca ccagcatggc aatcacttcg cgacaatgat
    13321 gatccattag ggaaaggcca aaaattagtt gttcaaatgg ttgaaacata tggttcaaat
    13381 aaaaaaccag tctttgtcga agaattagat gcactagctg ttcaaaaaca agcaggctta
    13441 gccaatgcac cagtgatgat ttatagcgaa gatactacac atatcgtgac agaagaagga
    13501 attgcttatt tgtacaaagc aaaaacaaaa gaagaacgac aagcagcaat tgcagcaatt
    13561 ggcggtgtta cacctcttgg aatgactagc acgaaagaat cactagatag cttgcgtgca
    13621 gccggcatcg tgaaattacc agaagatcta ggcatcaaac gtagtgaagc gaaacgttca
    13681 ttattagctg cacaaaccat cgatgatttg atcgaatggt cagatggcct gtatgaacca
    13741 ccaatgaaat tcagaacttg gtcataaaat tggcgagaaa aaccttttgt cgccatttac
    13801 ccagatggaa gaagaaagac gaataagcag aacgtgtatg ctctgtttta caaaaagggg
    13861 agagatccat ggaacaatta gcttataaat atccaacgaa acagccgatc aataagaaaa
    13921 tccatgtagg agtggtcggt tcaggagatt tggaaatctt gatgtttcca acagaaaaaa
    13981 cagaatctac tgtaaaaatt tgtacaggaa gcgatggctt cggcgaagta tggaacaatg
    14041 tattaacgag attttttgat cgttatccaa tttcagcaga tatcgtgatc aatgacttcg
    14101 gtgctacacc aggagttgtg tacctacgat tgacgcaagc aatggaggaa ctttcagatg
    14161 aaaaatagtt ttgtagaatt aaacgccaga gaacgagtga acgctctact tgacaatgga
    14221 cgtgaattga ttgatccatt cgatcaaatc atcgcgccaa gtttaccagc acaaggaatc
    14281 gtccctgaaa gtgatgacgg gatcgttgtc agccgtggca cgatcaatgg caaacaagca
    14341 gtagtaatcg ctatggaagg aaaattccaa ggtggcggta tcggtgaagt ttccggtgca
    14401 aaaatcgttg ctgcacttga acatgtgtta gaagaaaata aaaaaggaaa tgagatcttt
    14461 ccagtcattg tactagatac aggtggtgtt cgtttgcaag aagcaaacta cggactgtta
    14521 tctatttcag aaatcggaaa tgtaatcatt gctctaaaac aatatgtacc agtcatcggt
    14581 ttgattccag gacgtgtagg atcatttggc ggtatgtcga ttacttcagc attaatgagt
    14641 tatttaatcg caacaaaaaa agcgagagtc ggtttgaatg gaccagaagt tattgaacaa
    14701 gaagcaggcg ttcgagaatt tgattctagt gacaaagact tgatttggaa tacattagga
    14761 tctcgtcaac gggtagaatc aaaaatcatt gatgaattag tgactgatag tgtagaagca
    14821 atcaaagctg ctgtcatcgc agcaatggac gaacgaaaag acacgcatcg cagtgaaagc
    14881 tcagcatttt atttatcatt acttgattct ttagatcttt caaaaccaat ggccattgac
    14941 gattacaatg aagcaattgc taaccatcaa gcaaaatcaa ttgacttacc agaagtagca
    15001 gaaggaaatg aaccagctgc agcaagtgtt ggttacgatt ggtttgcggc actaactggc
    15061 atgaaaaatc caacttcttc tattagtact gtgtattatg gtaaatcaag taaattcata
    15121 gaagaagcca tcgtgacatc aatcgtacct gatcctaaaa acccgatgta ccgtgtacga
    15181 aacggtgaag ttggtttagt tgaaggtttc cgcatgggac aaattttgga tcacgtttac
    15241 gaagaagata aagacaaaaa agtgaaacgg ccaatcatcg ttgtgatcga tgtaccaagc
    15301 caagcatacg gctataacga agaattgatc ggtatccatg tggctttggc taatagtgct
    15361 gctgcttatg caaaactccg tcaagctgga catccagtta ttggattgat tgcaggaaat
    15421 gctatttcag gtgcattttt agcacatgga ttacaatcaa gccgcttgat tgctttaaac
    15481 aataaagaaa ttaccgtcca agcgatgtct aaagaaagtg ctgcacgtgt gacaaaacgt
    15541 tcggttgctg aaatcgaagc agctgctgaa aaagttccag ctatcgctta cgatatcaat
    15601 aattatacaa aactaggagc gatctatcat ttcctagaag atatcaccga ccaagctgct
    15661 tcagaacaaa atgtcagcaa agtcatcgaa gcaatcaatg aagccattca agatgtccgc
    15721 aatacaaatg acacgatgct gacaaatcga tacacaaacg aaacagccaa aacattcgga
    15781 cgtgtcgaaa caaataaagt ccgtgccaaa atggacgaag aatgggatgc ataaaaaatg
    15841 attcaagcac atgatattgt cctttttgat aaacatgaaa tagaagggtt caccttgcct
    15901 gaatgggtcg ttctaactga aaagatgttc ggaacagttc gtcgtgcgtc gacggatcac
    15961 gcagaaatac taccgattgg tttacgtgga cctgcccgca atcagagatg gtcaacagaa
    16021 atctcaaaac atgccgtcaa acaagtcatt catccgtggg acatcatcga acaagaatcg
    16081 tatagacaag agaaaatcat ggattatcct gtttatcagc aatttcatgc tgctagaaac
    16141 atattatcag gatgtaaatg gggaatcggc ggcagcttag gatttgaatt atcgactggg
    16201 attccggcag taaaagaaac cagtgatttt gatttgctgc tgtacgcaaa ttcaccgatt
    16261 gaattgccaa ttcaggtaat tcaatcgcat cctgcttttt ttgagcaatt cgatacccaa
    16321 gtagtgactc ggcaaggcgg tttttcacta aaagagtatt tgagagagcc agagaaaaaa
    16381 attctattga aaacagtcga aggacctaaa ttaaccaaag aactttggta ataaagaaaa
    16441 agagagagaa agagatgttt gaaaacaaaa aaatcaaaat caacgtaagt gacttccaga
    16501 aagtatcagc tgtaacggct gttatgatgc aaacgatatt gagctttgct ttggcaaaca
    16561 gccacagcgc aacaaataca gcttttcttg gtacctttta cgtcatcgtt aaatacacag
    16621 caccaatgtt tatttttgca attgtttata atatggtaaa aacaagtcag catttgtctt
    16681 attgggaatt tttgaaagaa aagttttttg aactagtcgt tccgtatctt ctatggacga
    16741 cggcttatct ttggctattt ccagcagtcc aacaacaaac tccgtatacg gatactgcaa
    16801 gctttttact gaaatatgtc acaggtgatg gagcgcctca tttatggtat accgttatga
    16861 tgctgcagat ccaattgttc atgccgtttt ttgtttggct cggttacaaa gtatttgcta
    16921 ataaaaaata tgtatggcca gtattgattg gttcaacgat tttatatgtc gcatggtatc
    16981 tgttctatca aacacaagta ttgactgggc cttatcatga cagctggtac ttattagatc
    17041 ggtttgttgc tagtttcatg atttatgggg tagccgcatt tgtttatcac gaaaaagtct
    17101 atcaatattt ggacagagta cgttatcttt tcttacctgt tgccttagtt atcgcgttct
    17161 tttctgtccg ttcattgctc gcacatccag gagacttgag ctttgcgaat gcaccttact
    17221 tgaatacgat ccaaagttta tacagtttag tcatcatctt tgctgtcttc ataggcgctt
    17281 ccaaaatgat tgtaaacgat tcgccaaaat tgccattgtt caaatggttg tctgtttatg
    17341 cttatcgtac gtatttagcc aatgtatttg ttttccaagt actgttatta ttgtttaaag
    17401 atagttggct gcagttacct tcaggagtca tgattcttgt agcttatcta atgacggcaa
    17461 gttgtgcatt tgctttaagc tggttacttc atatcatttg ggtagctatc aaaaaaggtt
    17521 tcagcaagta atagtaggaa gaaggagtga gtgtcatgat aaatgacgaa cgaaaaaaag
    17581 cagtgactca gcaactcgct gcgttggtag aggaagcatt gatcgcagaa gtaacattaa
    17641 gtccaaaacc tggattagtg gatgcactgg atgcgggtgc acattccgat atggactatg
    17701 ctttatttct taagtctgct aagacgctaa ctcctttttt tgaagaaatg gctcaaatag
    17761 catggcatca tgctattgat caggagttaa gagaaagaat tgctgagatt gggcgaaaag
    17821 cggaaaaggc aatgctgatt gctacaaatg gcatcaatac ccataaagga gcgatttggg
    17881 caatggggct attgatcagt gtcattgcac aaaaaatcag tatggaacag cctttttctt
    17941 tatcgaaaat acttgatgat gtcagcaagc ttgctgcttt tcctgataca aaatatcgtc
    18001 ataaaaaaac cactcatggt catagggtga agcaaaaata tggcgtaaat ggtgcatatg
    18061 aagaagcgat attagggtat ccgcatatca ggcttgcaat tcaagcagct aaggagctag
    18121 ataatgattc atatgtacag aaacaaatgc atatgttgtt agttttgatg agttcgctag
    18181 atgacacatg cgtattgcat cgcagtgatc agaaaacgtt agtggaaatg caaaaacttg
    18241 ctcatgctgc tagtcaaagt gctttaccaa atcgtccatt tacagcactg ttgcactttt
    18301 gtcaggaaaa ccaaatctct cctggaggaa gcgcagatct cttgtctgca agcttgttca
    18361 tgctgaagat agaggaatta tggactgccg acacatacat ttgtccgatg ttactcaatg
    18421 actaaataag acaaaattgc taaaaaaaca gtttatgcat ctggttattg actcttcctt
    18481 ttagcaaggc tatcataaaa atagtttttt gtaataaaag ataacgagga agacaatgaa
    18541 aaaaatcaat tatttagcaa tcattttgtt agtgggccta tgtttgtttg ctctgccgac
    18601 ccaaggattc gctgtcgcgg gtggtcatgg tggaggtaca tctagcggtc gaagttcggg
    18661 cagaggttca tttggtggtc gttcatatgg gggcagttat tttggcagtc gttcttacgg
    18721 cagagattct tatgggtatt atggtccagg tacaggtcct tctagttatg agcaaacggg
    18781 atttcttgca ttagctgttt tgtcagtagg aggggtttct gctttttcta tcgtcaagaa
    18841 taaaagacaa aagaaaaggc tgaaagcgga gatattgtcc cgcatgtcag gaacggctaa
    18901 agaaaagaaa gcacagtttc tggaaatcca aaagatattc atgaagatcc aatccgcttg
    18961 ggaagaagaa actcctgaaa aagccagaag ctgttataca gacaagctgt ttgccgaaca
    19021 tcagaaagtt ctgcaaaaaa acaaagcaga cggtgtaaga aatcatacta aaaaaataac
    19081 tattcaggaa gtaggaaatt atcgacagat ccacgaaaat agttttgcca tccgaattga
    19141 tttcagatgc tgtgattatt cagtcgatcg aaaagatggg cgattgatct caggaagtaa
    19201 gacacaacga cagtattttt ctcagatatg gtattttgat ttttctgaga aagaaaaaag
    19261 atggcaagcc gattttattc agccgattat gctggattga caggaaatat ttatgaacgg
    19321 agttgtgaca aaagccttgt cgcagctcct ttttctgaat aaacggtgtg ccagagatag
    19381 cctatcggca ataaggcacg attttgtaaa atatgggaag cgatttttca aaatcgcttc
    19441 ttatcgctca aggctgaaca tctctgtcac aacctctcca ctaaatggtg tttaaaagct
    19501 tgcatctgcg ataataagaa caaccaaacg aaaaatagga agcactattt tagtttagtt
    19561 gttcttatta cttgatgcag gacagctttt tcacaacctc ttttttgtat agatgggcaa
    19621 aatttttgta ataataggcg tatgtctttt tcgttgagga gatgaaaaag catatggctt
    19681 attttttgtt tgctttgctt actttctttc cacttcaagt ggcagaaata tctacttttt
    19741 attatgtaag cggaaccata tacttgaaat cagaaggaga tcatttctat gaaaacaaga
    19801 acaattgaaa tacttcacag aatcatgaca gcccaatatc cagtaaaagc aaaacatcta
    19861 gcaagtgagt tcaatgtcag tcagcggacg atccgtcagg aagttcttga agcgaatatc
    19921 tggttgagca gtaaaaagct tccggagatc cgtacaattc gcaacaaagg ttttttgttg
    19981 aagctggaaa aggaaaagca agctcgatta gaaactgaaa taaaagatgt gaaagacggc
    20041 tttttgaatc ggcgcgaacg tatttttgat ctagttttag ccgttgctta cagccgaatc
    20101 ccgatccatc taaacaaaaa agaagaagaa tttcaaatct ctaaaagtac attagatgaa
    20161 gatatgagac ggttacgagc aacactggtc agttatggga tagagatcgt cagttatgga
    20221 aagcaaggac tggtttataa aggttcagaa cgatctatcc gtacgatgat ctatgatttt
    20281 atcaatcaga atctgggaat gaccgacttc tttatgaatc aagatgcaca attaacaccg
    20341 gctcaaaaaa tctttctcca ttattttcct ttggtggaaa tcaaaaaaat acaggagatc
    20401 tattccaata agttgttgaa acaagaagat gatatttata aaaaacaaat cctgcttttt
    20461 acattgatct ggatccagcg aatcaggaaa catgaattta tctctgccat taattggaaa
    20521 aatacagaaa taaaagacag tagcttttct gcatttattg accacatgat cgaggaattt
    20581 caattggaca atgtcccgca agtagaaaga aattatcttc gtttcactat tgagacgttc
    20641 aatgctagag atatctccaa ttcaatcgag tgggtacaag ctcaattact aacgatccaa
    20701 ttgatccaat ttgtagagaa cgagacacac gtacctttcc atctaaagga agaagcttta
    20761 ttcgaaaatc tctataagca catggctgca ctgattgtaa gaatcaagaa tcatatccaa
    20821 gtcatgaatc cattgaaaga aaacatccga acaaattatt tcccaatcta ccgcgcagtc
    20881 actcattttg ttcctacgat cgaagaagta attggtggca agatactgga ggacgagata
    20941 gcttttcttg tcatccactt ttcgacgatc gccagtgtaa tcaagcgaga cttgaattat
    21001 gtttataaat cagtcgttgt ctgtaaccat gggatggcta ctggaaatct gttagcagag
    21061 aatctgaaag aaaagtttcc tcagatcgag attactgcag ttttaagttc aaaagaaatc
    21121 gaattagtag ataaattgga tgtcaatctg gttttcagca cctttcaatt gaattatcga
    21181 aataagccgc ttttagttgt cgatccgatt ttaactgaga cgaatatctt ggttatagaa
    21241 gactttttga aaagaaatga agaactacag cggttagagc ctaacagtca tgaatcgacg
    21301 gagttattca ctcaaataat agatgtcatg aaagaaagtg gtggccgagt agatcgaatc
    21361 atctatggca agttagaaaa attattcgaa acaaacaatt tagaaatcaa caaaagggag
    21421 atccagccta tgttaaaaga tattttgacg gacagcaata tcatgatcaa agaaaaagcc
    21481 actacttggg aggaatcgat tgaactagct gctagaccat tggttaaaga aaacattgtc
    21541 gaagagcgct atgtcgaagc gatgattcgt gcagtgaatg attacggacc gtatatcgtg
    21601 attggcaaac acatggcact agcccatgcc cgaccagaag atggggtcaa taaattagga
    21661 gtcagcgtag ctacgattga gcaaccaatc gatttcggta atcctgaaat ggatccagta
    21721 aagattattt tttgtttggc agcagtagac tcctactcgc atctgaacat catgaaagaa
    21781 ctaattgaat tgatcaacaa cgaagagaag ttggatcgat tgattgaatg cacaaatatc
    21841 gaagatttca aacaactgct tttttcagta gttgagaaat aataaatgat acgggggaga
    21901 acaaagatga acaaattgaa cattttattc gtatgcggtg caggtttagg aagtagtttt
    21961 gcagcacaga tgtctgctga ggatgttttg aacaaattag gagtagaagc caaactggac
    22021 cattgtgata tttcttccgc agtttccatg aaaccagatg tgatcatcac agcagaaaat
    22081 tttcgttcgc agttcgaaaa gttcgcagtt gatcctaaaa cggcgatgat ctatttgaaa
    22141 aatattgttt caaaaaatga aattgaagaa aaaatcaccc cagttctgca agataaggga
    22201 gttatctaaa tacaaaaaga aaagagggta aaaa
//
LOCUS       DAZULR010000041        22026 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.041, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000041 DAZULR010000000
VERSION     DAZULR010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22026
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.041"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(61..1371)
                     /locus_tag="ACG8ZV_001942"
     CDS             complement(61..1371)
                     /locus_tag="ACG8ZV_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004650 - polygalacturonase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 28 protein"
                     /protein_id="HFS4997255.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     INFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1383..2801)
                     /locus_tag="ACG8ZV_001943"
     CDS             complement(1383..2801)
                     /locus_tag="ACG8ZV_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4997256.1"
                     /translation="MLSQNAVTANTVKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3041..4609)
                     /locus_tag="ACG8ZV_001944"
     CDS             complement(3041..4609)
                     /locus_tag="ACG8ZV_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HFS4997257.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(4613..4894)
                     /locus_tag="ACG8ZV_001945"
     CDS             complement(4613..4894)
                     /locus_tag="ACG8ZV_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HFS4997258.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAAGAFSLYRVRMRKGA"
     gene            complement(4891..5814)
                     /locus_tag="ACG8ZV_001946"
     CDS             complement(4891..5814)
                     /locus_tag="ACG8ZV_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030599 - pectinesterase activity
                     [Evidence IEA];
                     GO_process: GO:0042545 - cell wall modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pectinesterase family protein"
                     /protein_id="HFS4997259.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(5811..6689)
                     /locus_tag="ACG8ZV_001947"
     CDS             complement(5811..6689)
                     /locus_tag="ACG8ZV_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HFS4997260.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPTVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIETLLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(6676..8013)
                     /locus_tag="ACG8ZV_001948"
     CDS             complement(6676..8013)
                     /locus_tag="ACG8ZV_001948"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HFS4997261.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTSAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8016..9119)
                     /locus_tag="ACG8ZV_001949"
     CDS             complement(8016..9119)
                     /locus_tag="ACG8ZV_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFS4997262.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9193..10701)
                     /locus_tag="ACG8ZV_001950"
     CDS             complement(9193..10701)
                     /locus_tag="ACG8ZV_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFS4997263.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(10667..11359)
                     /locus_tag="ACG8ZV_001951"
     CDS             complement(10667..11359)
                     /locus_tag="ACG8ZV_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HFS4997264.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11381..12355)
                     /locus_tag="ACG8ZV_001952"
     CDS             complement(11381..12355)
                     /locus_tag="ACG8ZV_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4997265.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            12655..13527
                     /locus_tag="ACG8ZV_001953"
     CDS             12655..13527
                     /locus_tag="ACG8ZV_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4997266.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14109..16307)
                     /locus_tag="ACG8ZV_001954"
     CDS             complement(14109..16307)
                     /locus_tag="ACG8ZV_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4997267.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLFSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16539..17531
                     /locus_tag="ACG8ZV_001955"
     CDS             16539..17531
                     /locus_tag="ACG8ZV_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFS4997268.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNLAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17591..19012
                     /locus_tag="ACG8ZV_001956"
     CDS             17591..19012
                     /locus_tag="ACG8ZV_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HFS4997269.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19005..20504
                     /locus_tag="ACG8ZV_001957"
     CDS             19005..20504
                     /locus_tag="ACG8ZV_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HFS4997270.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20543..21937
                     /gene="uxaC"
                     /locus_tag="ACG8ZV_001958"
     CDS             20543..21937
                     /gene="uxaC"
                     /locus_tag="ACG8ZV_001958"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008880 - glucuronate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HFS4997271.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYLTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
BASE COUNT         6669 a         4494 c         3823 g         7040 t
ORIGIN      
        1 atcattaaaa aaaataaagg tcaagctaaa atattattta agcttgacct tattataatt
       61 tcaacgattg tcaaaagtat tgtttgcagc tgtgttgcca gtttctatag ataaatcaca
      121 gcttttgaaa cataagtttt gtactgcttc gattcgcccg aattcttttg cagttatttg
      181 gcaatgagaa aagcagacat cttctatagg cttttcagga aatgctacta aatcaaaagc
      241 tcgggaagga agtgagtaac ctggagaaag gcatgcctgt acgtttttga tgtgtatgtc
      301 tttgactttc gtcatttgct ttgattcagg tatttcttca gccactgctt gccaactttc
      361 tggcatttga gcaaggtcat tgctattttt tctattgtat tcattatgcc agtccattat
      421 ccaagaaaaa ggaaattgta catcaatcat attcagattt tctaccctga tattttcgat
      481 cactccccct ctttcttttg aagatttcat tcgaatacca cagtctgact gaaaaaaatt
      541 gatatcgtga atatatacgt cactaactcc agcactaact tcgctaccaa tagttacacc
      601 gtatcctgaa cggattttac atctagcaac ctcgattctt gatgattttc gattgactct
      661 tgcaccattg ccatctctgc cagacttaat agcaatacaa tcatcaccac aggccaaatc
      721 acattcatag acacgcacat ttgttgaaga atcaatatca atcccatctg tacttggtcc
      781 atcattgttg cggatgatta ctttttctac taatacatcg ttagaataag tgatttgcaa
      841 gttccaaaaa cctgatttct gaaaaatcaa atcacgaaca acaacatgtt ctgcatgata
      901 cagtaaacaa gcgcgtggac gtttaatagc ataatccgca atccaacgaa gtcccttttg
      961 atcgtattca gctcttgtcc cgcttttttg atcttttccc caatacagct cccaccaatg
     1021 gtctccttga ccgtcgatta ttccttttcc ttctataaga atatctttcg ccgagagaac
     1081 attcaaaatc gctgctggcc atttcatttc tacgccggct actcgtgtat cgatttctgg
     1141 aaatgcttcg atatctgttc tccccttgag gactgcacct tcttcaaaga taagatgact
     1201 cttatctttt aaaaaaaggg ctccgactaa ataaatgcct tttggaataa atacaggtaa
     1261 gtgttctttc gcaccttgat cgattgcttt ttgcagtatt attgtatcat cttgttgagt
     1321 gtcgtttgtt ttaaagttca aagcattgat aatccctttt tttgtccgca atacgtttct
     1381 ccctatcttt cattgatttt tttcaattct tcaccaataa atacagtttt tgaacgattc
     1441 agtgggtaac ctactagcaa aatgattgcg gatacaaata agcagaatgc tggtaacaag
     1501 tttgccatcg tataaatcct ttcttgtact aaaactgatt ggatggctcc acctgttgta
     1561 gacgattggt aaccaatgag tgccagcata aatccgccta ccgctcctgc acatgcttgt
     1621 cctacttttc tcgcaaaaga atttactcca tatactgttc catcttctct taagcctgtc
     1681 ttatattgat gataatcaat cacgtcagta atgaatgccc agaccatcaa attgaataaa
     1741 ccagatccta aagtagcgat aaataaaaga atcagatata cccatgcatt tgttatatga
     1801 aggaaataca tcagcaagta catacatgaa gaagcaagta acgcaaatac gcttgcttcc
     1861 tttttaccaa ataattttgt cagctttgta gcaaatggtg ctaaaactac tactgttccg
     1921 taagtaaata aaagagcaac agacattgct tgtttattat ggaagtaatc attgaataaa
     1981 taagtcatat tcgtcccagc taaaatctga ttgatcacaa tgaaaatgtc aacaatgact
     2041 aaaataatca gtgctcgatt agctaacaaa ccttttacca actgagaagc agatactttt
     2101 tcgtttttga caactcttac tctttcagta gtcaatttac aagttaacat atatgcgaca
     2161 aatgctattg cagcacatcc gattgaaatc caaaagaaat gattccctga aacgacttgt
     2221 tgtccactct tgttatgggt atacattaaa atcggaatga agaatcctgt agttgatccg
     2281 ccaatcgcag aaccaatgct tcggaacgtg gacaacgagg tgcggtcatt aggatttgag
     2341 ctaattgctg ctgccattgc tccatacggg atattgattg ttgagagaaa aatcccataa
     2401 acaatgtatg aaacaaaaat ataagcaatc ttcaccgtca ttggaagatg ttggacgaat
     2461 ggcaaaaaca aaatgacagt cactaagcaa aatggatact tcatttttct gatccaagga
     2521 ataaatcggc cagtttctgt taactctgag acatcacata atcttccaac catcacatca
     2581 gcaaacgcat ccaaaattct cgaaatcaag aataacgtac ctacgattgc ccctgaaacg
     2641 ccaagaacat tcgtataata aatcatcaag aaactattga ctaaacctaa aataaaacag
     2701 ttacctagat caccgaacat gtagcctatc ttatcggaaa tcccaaattc ctttttttct
     2761 ttttttactg tatttgctgt aacagcattt tgtgaaagca tttgaattcc tcctacctct
     2821 tctagtaaac gttttcaaaa ttataactct ttttttcttg tttttatatt cacaatgttg
     2881 gctttttatt gcattatctt gacagataaa aaacaaaaaa taatctaaaa acattgatgc
     2941 ataagattga taactttttt tacataacaa tatatacaaa caaaaaaatt cactaactag
     3001 tgaaaataag ttagtgaacc tcatttatta aagaattaaa ttacagatga tcttttccat
     3061 catacttgaa aaactcaaaa tcagcataac ttcctctttt tttatttaga tcatgcactg
     3121 ctatcccgat aaaatttcca gtaaaccctc ctgagagtat acacatgttt ttttgcggac
     3181 ctactttctt ccattcttca gttgatacgt ctttcaaatg aaactgtgct gtctctttct
     3241 ttacagtgac tttcaaaaaa gtcttctttt ctgtgagtgg aatcgtccaa tcttctattt
     3301 gtgctactcc gttttctgat tctatcatac gtaggcattt tcccttgtcc tcattccaag
     3361 taacataaca ataaatataa ttggattcat ttaagtacag taccagtcca gccatctgat
     3421 taaaattatt aggcatgtat tcaaatgctg tctccgcatc aaaagtaaaa tccgtttgcc
     3481 gaatagctaa caaatgatgt tcgaaggtag attgaagaga ttcaccggaa atcagacgta
     3541 aaaaacctgg tctacatttt gtatcacacc aatcagcatt tggcaaaatg cgtctggcat
     3601 tccagttctt ctttagctct ccttcaaatg tatccataaa ctgatgatct ttttcttgtt
     3661 gtacctcttc atttgtctca atcattattt cttccatcgg agttgtctgg ctatctttaa
     3721 gtcttaacca atcgtcggac gtccaataca cttcttgaat agcggtttct cttcccaaaa
     3781 tagccgcacc gtttaatggt ctggtacaaa gatatgtcat gtaccatctt cctgacgggg
     3841 tttgtactaa gctcccatgt cctgtacatt gcaatgtaga agcaggtttg tcactagctg
     3901 tcagcatagg aaaaccagga tcaagctcgt aaggaccagt aatattcttt gctcggcaaa
     3961 ctgtaactga atgtcctctt cctgtaccgc cttctgccgt catcaaataa taatacccgt
     4021 tacgaaaata caaatgtggt gcctccgttt tcgctaattc tgtacctgca aatattttat
     4081 agatgggacc atcaagcttc ttcttctctg catcatattc ttgtaatacg ataccgctgg
     4141 atttattcgg tgtgtccaga cgataatccc atagttcatt gacaagccat ttttttcccg
     4201 tttcaagatc atggaacaaa gaaggatcaa agccgttact atttaaataa attggttcgg
     4261 accaaggacc tgtgatctca gatgcagtga tcaaataatt gtggacatct ttaaacggac
     4321 ggcctgcact tttgacatct gtgtaaacaa gataaaacaa tccatcagca taactgatct
     4381 gtggcgccca tatacttcca tttgtaggat ttccttgcaa agatacttga gtggtcaaaa
     4441 tatccgttgt atgtgaccag ttgactaaat ttttcgactc atatactcgg attcctggaa
     4501 gccattcaaa agaggagaca ataatgtaat accgctcttt cactcttaat atattaggat
     4561 ctggattgaa tcctcttaaa ataggatttt tcactttgat agtctgcatg attcaggctc
     4621 cttttctcat tcttactcga tataaactga atgccccagc tgctaaaaaa gcaagtgaaa
     4681 taaacaacac aacggcaaac agaccagtca tgtcctgtaa taatccaaat gtattttcta
     4741 aagacaaagt tgaatgatct acagcaagcg actgataact ttttttaaac tctgacgcag
     4801 acatattact taaagtaact gctaacccgc caaagaaaat caaagataga ctgccaccga
     4861 ccattcctag caatagttcc cattttcttt tcatttctga accccctgct tttctaaatg
     4921 tatccattca ggtcttttga tcgatgtttc ataattgtta ttacgttcag agaatttgac
     4981 agtctgttca tttttcttgt catcccaatt atcccaacca gttgggtgaa catgcccacc
     5041 tatcttacac gcttcaaata agacatttgc atacggacgc cacggtcttc ctaaatagac
     5101 gtttctagta tcaggttctg cagtcaaggt acagctttca aaacgatacc ctgttttttg
     5161 atttttcggc gtagatgctg ctgtgatgta tccaggattt ttactggcta agctatggat
     5221 atgacactga tgaaaaacgg catctgcccc accaaatatg aaatccaccg ttccttcaat
     5281 ccagcaatat tcataggtct gacgacaata ctcaggattg gcagaagccg gtgtacaaaa
     5341 aggagtacca tctttttgca aatcaggcaa cggacccgtg cataaggtat cctgataacc
     5401 agatagtcga cagtttttta aagatacgcg atctcctgaa ttgaataaag caacagcctg
     5461 tcctaccttt tctcctggac ctgctgtatt ttcgatgtga agattttcta atacgacatt
     5521 cgatccttct aagaaaaaag tagcacttcg gaaagtccct aactggctac cgtcaagata
     5581 ctcctgtttt gcaaaacgat taccggagat aactactgtt cctgctccca caagtttaaa
     5641 attggataat ctgctttcta tatattcatc atatcttcct tcttttacta tcaagacctt
     5701 tggatggcta tccggcaggc ctgccaaata atcgattcct tcttggatag tttcaaaatc
     5761 cgtcggggta tctatagcat tctttccaat tatcagtttg tctttcatcc tcataaatgc
     5821 tcccttatga attgtttcca aatatttctc atttcttgtg tttccatatg accgcctgtt
     5881 aaagaaaaag aagaaaagtt ttctggacta cccattgatt gatacttttt gtccagccct
     5941 tttctcagct tcagtacgcc ttcgtccaag cacatcgtat cgttttttcc aactaagcta
     6001 agacgagggc gcggagcgat tttttcttgg attgctaacg ttgtataagc tgtcaataga
     6061 tttggcacat agtaataaaa cccatgatga tctaggcggc gatgtagcaa aagtgtttcg
     6121 atgtccacct gtgccgctag atcaatacaa actttgacac gagaatccaa tgctgtcacc
     6181 caccagctta ataagcctcc catagaaaga ccaatcgttg cgagccgttg agtatctgtg
     6241 tcttcccttg tctccaaata atcgatcaag ctgatcacat cataaatacg cattccccat
     6301 aacgtttttc ctgttaataa aaattgtttg aacaactcgc tttcagaaat acctccgcgt
     6361 tcttcaaatc cccaagcatc aatcgaccaa acagcatatc ccattcctgt cagtacttct
     6421 gcaaaagatg gagaagctaa gtaaggagca ccatggatca attcactttt cccgactgaa
     6481 aaatctccgc cgtgagaatg caggtaaagg accgtcggaa acggtccttc tttttctgga
     6541 taagcataga gggctggtac tgtttccaat tcatttaagt acaattgata gtattcaagc
     6601 ataaaaccgt tttgtttttc tcggtataat cgttttccac taggggtatg tctgctagat
     6661 ggagcaccta aaaaatcatt caactgcata agcaaagttt ttacgaacaa ccagttcatc
     6721 catattttct gattgatttg attggaattt ctcaatactg atttctttag tattttctaa
     6781 tagaaatgct ggtccctcgt gattttcaat cgacatctgg ttaaaggaaa ccttacccgc
     6841 aaagccaata taaaatcctt gtctgctcat ttcctctatt cctgtcatca tagcaggaac
     6901 accgggaact gcatcttggg ccatcgagac atcgatattg tcaaatgtga tttcttgtat
     6961 gaattgttcc gctaatccat aaataaaacc tgcagaagca tggacattcc ttgccgtgat
     7021 attcgaaaaa tggatccttc tgaatgctga tgtccgttca tctatcggat aagccttttt
     7081 ttcccataca tacggttctt tccctcgcgg accacagaaa taataaagat tcagtataaa
     7141 tggacacatc acattatcca tgactatatt ggatactcga atatcttcaa cgatcccgcc
     7201 tcgacctcgt ctagatttca atcgtattcc tcgatcagtt tcttggaaga tacaatttga
     7261 aatggtaata ttacgaatac taccactcat ttcacttcct aatacgacac cgccatgtcc
     7321 atggaccatc gtgcaatttg tgatcgtgat attttcgcaa gcgatccttt cgtacgtatc
     7381 ttcagtccct gccttgattg caatacagtc atctcccacg tcaatatggc aattactaat
     7441 acgcacattt ttgcatgatt ctggatcaat tccgtctgta tttggtgaat ccgctgggtt
     7501 caagatcgtc aagttatcaa acgttgcatt actgcaaaga atcgggttga tcgtccaact
     7561 tggtgactgg atcaatttaa tatctttcac agtaattcga tgacagttat ggaaactcat
     7621 caatttagga cgaggataag cgagattatc tggttcattt ctaaaagtat gccaccattt
     7681 ttttccattt ccatctaatg taccgaaacc agtgacagag atgttctcta cattttgagc
     7741 atagatacag gaagcataaa cttttcgatg gactccttcc caacgtgaat gaacaacagg
     7801 ataatctttt ggatcgtcag agaatttcag aaccgctcct gcgcttaaat gaagttcgac
     7861 attgcttttt aaaaataaag ctcctgttag aaattcacct gctggaacaa ctacggtccc
     7921 gcctccgtca cttgctgcag catcaatggc ttgttgtatt gcttcagtat tcaattcatc
     7981 aattgatgcg ccaaatgtca aaatatcata catatttata atgcctccac ttcaatcaat
     8041 gcttgcaaga atgcaccaac gcctttttga tcattacaaa taattggttc actgatgtag
     8101 taagcatatg aaccatctcg ctgatctgct ccgcctaacc ctgctacttg acagttttta
     8161 ttcaagttca gccagccttc ttttgtttcc agaacaaatt catcaagtaa tccttgatgt
     8221 gatttcttca cttgtggaag ccattcttct ttgttcagca gtcccaaacg tattccttta
     8281 gccattgcgt aaacaaacat actactgccg gaagcttcca gataatttcc tttccgtttt
     8341 gtttctgttg ttacttgata ccatgtcccg ctgttttctt cttgatatgg aagtaatgca
     8401 gccagtgtct tttctagaat ttctttcagc aaagaacaat ctgtttcttc atgaagtaat
     8461 tcataggtat ctgctgcagc catcaaatac cagccaatcg atcggctcca aaaatgatgg
     8521 gatagacctg tttttggatc agcccatggt tggaccttct tttcatccca tgcatgaatc
     8581 agcaaatttg tttttggatc gaatagatgt ttataactga tttcaaactg tctcaaaaca
     8641 tcttggtaat ctttttcttc actaaaattc tggataaatt cagcataaaa aggagaaccc
     8701 atatataagc catccaacca aatttgataa ggataaattt ctttatgcca aaaagctcct
     8761 tcggatgtgc gtggatggtt tgccaactgc tgggaaagga gttctgctgc ttttttatat
     8821 ttttcttcgc ctgtttcttt gtacaataaa aagaaaagct ttcctgtatt tacatggtcg
     8881 atattgtatt cttcaacgct gtagccacgg atcgttccat cttcttgcac gaaatagtcg
     8941 atattgtctt ttatgaaatc aaaataaatt ttttcttggg ttcgttccca aagtaattgg
     9001 aaccctttaa gtacgacgcc atagtcataa gaccattttc ctttatacca cttttcttca
     9061 tataagcgag gtgttctttc catgatactt tttgctaatt tctttgacca gttttccatt
     9121 atttgctctc ctttaaaaat taaaatagga tttgggacaa ataccaagaa gtatttgtcc
     9181 caatcgtcta tattactgtg ccgctgcttt gtatgcttcc tcgtactctt gtgtgattcg
     9241 atcgcctcct tgtgctttcc agtcttctac agcttttttg aatccatctt cgtcaagctg
     9301 tcccatgatg tattgcaccg tagcatcaat gacgattttt tcaatttctg atcctacttc
     9361 attgttcgtc ggtgaatcca atggcacaga aggatccatt acagcaaatt cttcattttc
     9421 tttgatcaat tgattagaga attctttttc agggtctgta tctttgaaag agaacgtcac
     9481 ttcactagga cgagagcttg ataacggttg cacctcttgt tgccaaagat ccatatcgat
     9541 aaattcgata gaaccatcat cattcaattc ataatgcgtt ccttcgatac cgccagtcat
     9601 caatttatac acatcttctt ctaaaagatc atcaacaaat tgaagtaatt tcttcaattg
     9661 tgcttcgtct tttacttgag atttgggaaa tgctagcaag ccgccaatac catttccttc
     9721 tgaccaaaca tgataaccgc cgccttcacc atctgagatc ttgtttacag gcactaattc
     9781 catatcatct tgaatacctt gacccatcgt cttcagattc ttgatatcca ccattccagt
     9841 gtagattcca gttcttcctt gtgcaaattg ttcttgctga tcagtctttt gggtaactgc
     9901 aaagtcttgt gccaaatagc cattctcaaa tagatctctt gaaaaattca aagctttcat
     9961 atactcttct gtatcaaatt ctggagtgaa tttgccatta tcgtctacag cccagccatt
    10021 tggtgctcca aaataagaag tgaaaagttt aaagctggta taacgaatat cactaggcgc
    10081 acgatcgcca aaaccaactg tgtcgtccac accatttcca tcaggatcgt tttctgtaaa
    10141 ttgtttagct acttcataaa gctcatccat ggtagttgga acatctagtc ctagattatc
    10201 caaccagtct tttcgaatga ctaagccagc acgagcgtag tctttttgta tcggtacgcc
    10261 gtacaaggca ccgtcgatac tcgcagcttc gattctatct tcagaaattt gacttaaatt
    10321 tttatagtct tttaaatatt ctgatacatc ccagaatacg cctgatttta acgcattgcg
    10381 gacagaagag tttttcaaca tcgcaatttg aagtgtaacg atatctccta gttcatcaga
    10441 agccaatgca gttgttaatc tttcttcttt tgaagcatca ggaatccagt tgaatgtcag
    10501 ttccgtatcg gttttttctt cgatcaagtt cacaatcgtg tctgtaggcg gtgaagcatg
    10561 atgcaaaata tttaaccaag tgattttagc ttttccatct tctgtctctg aagaactgtt
    10621 acttgaactg ctgccgcatg cggcaagtgc tagaattcct gcaaaactaa gacctaattt
    10681 tacgagcgtt gcttttttca taaattttct ccttcactgt tttaataata tttttgtttt
    10741 cttctgtttt ttctgtatat gagttcttcc attccaaatg gcaaaatata gaatttgctg
    10801 tccacgtgac tgcggaaaag aagagactgc caccgataaa ggttaaaaca cctggcattg
    10861 tttggatgat catcagataa atccctacca tacttaatat caacactaat gagtaatgaa
    10921 gatgtgagaa tccgaataaa aatgccattt tcattttgaa aaaatatcct ttccaatcat
    10981 aatgagccat gattgggaaa atatagagtg ctgagagcac atatatgaac gcagcaatat
    11041 acaaagcgat cctaagatac caattgtgta tgaaagaaag atccacaagt aaaacaatcc
    11101 cgatggcgcc atatatccag ctcatcagca aggtttcacg atagttttct ttaaaatatg
    11161 tgaagtacgt tttcgtcaaa ggaaacgttt cttttgagcg cagccatttt ctaatcactg
    11221 caaccatcgc atacgatgca ggaccgaaag taaaaactcc caaacctgcg atgactaaac
    11281 cgccccacag aaaattcaaa taaaccaact gtaaaatacg atttagcctt ccgtttattt
    11341 tatctaatga ctgcagcata tctttccctc tctttctatc ttagtaaacg ccgtcttctc
    11401 ctagcttttt ggcaatctta ttagctaaaa ttaccataaa caatcctacg acccctttaa
    11461 acaatcccat tgctgtactg aaacttaact gtccattctt caatccagct gtataaatat
    11521 aggtgtcgaa aatttctgca acgcttcgat tcaatgaatt caataacaag tacatatgct
    11581 cgaaccctaa gtctaatgtc tgaccgattt ttagaatcag caaggtaatg attactggac
    11641 gaattgccgg caatgtaaca tgccatgttt tgcgtaagcg tcctgctcca tccatttctg
    11701 cagcttcata caactgtgta tcgactgcag ttatcgctga aaggtagatg atcgtagacc
    11761 agcccaactc tttccagatc acttgtccga tatatactgt gcgtgtccat tcaggggatg
    11821 ttagaaaact gattttttca aatcccattg ttgcaaggaa ttcattcaat acccctccgt
    11881 caacattcaa aaatacataa gtaatcgaaa caatgattac ccaagacatg aagtgaggga
    11941 tgtaaatgat cgtttgaatc ccgtttttca atcgtttgtt cgttacttca tttaatagta
    12001 aagacaaaat gattggcatc ggaaaaaaca cgaagatatt taatccgaac aagatcaacg
    12061 tatttcttaa taatgtaaag aatgtcggtt ctgtaaacaa acgaatgaaa tgtttgaaac
    12121 cgacccaagg acttcccatt attcctaaaa atggttgata atcttgaaaa gcaataacga
    12181 gtccccccat aggaagatac ctaaaaatca agaaataaag gactcccggc agaatcatca
    12241 catataaaaa tttattcgtt ttgattcctg caattatttt ttttcgtctt ctgagctttt
    12301 cttctttttt cgatagcgtc agttgaaatg gttcttgttt ctttacactt tccataagcc
    12361 cctccttagt tttgtgaatg tttgctgctt atgacttcat gatagataac tatctgaatt
    12421 acgtatataa tcatttttat cgtaagtaaa aacgcttaca tagcaatgat ttttgtgcta
    12481 tacaaaacga taaagtgtat tttttcacaa ataaactacg catagcaaac cttctatttt
    12541 tttctatctg acacttagca taggaaatga ttatatacgt aatctttcac cgatgataaa
    12601 ttgaacatat agaaacagaa acatttaatt tattttgagg aggagcctat ctatatgaaa
    12661 aagaaagtct ctataggaga aagaagtttt acacttttca acaatacgtt tctaattttg
    12721 ctagctttga tctgtatcgt tcctttttta aatatcatcg ctacatcttt tgcttctaca
    12781 caagaagtcg tcgcgaaaaa gtttatcctt tttcctacta ccttttcttt agacgcgtat
    12841 cgctacattc tttctacgcc gaccattttt agagcacttg ctgtttcgat tggtgttaca
    12901 ggtgtcggaa cgatcgtcag tatgtgtgca acttcactga tggcctacgg tctttccaga
    12961 aagtatttgt ttggtcgagg tttcgtcaac tttcttgttg tattttctat gttgttcagc
    13021 ggggggatga ttccaacgtt cttagttgtt cgttctctag ggctggtcaa ttcttactgg
    13081 gccatgatcc tgcctgtggc tgttaatgca atgaatatga tcattatgag aaactttttc
    13141 caagccttgc cggatagttt ggaagaatca gcaaaaatgg atggttgcac agattttggt
    13201 gtatttttca aaattatgct gccattagct ttaccgtcta ttgctactat ctcgcttttt
    13261 tatgctgtta cttactggaa cacttatatg actgctattt tgtatatcaa cgattcatct
    13321 aaatggccga tacagattct tttacgccaa atcgtcattg tatcaagtgg gatgcaagca
    13381 gaaagtagtg ccgttgatgt gattccacca gcacaaacag ttaaaatggc tgttatcgtt
    13441 attgcaacag tgcctatgct gattgtttat ccttttgttc agaaatattt tgtcaaagga
    13501 gcactcgtag gttctgtcaa agggtgatta tgtactgaac gcaaaatggt agttgtgtca
    13561 gaagtggtca gcttcaagaa ataagaaggc atttacgaaa attgcttctt aaatttttgt
    13621 gaaatttcgg cttatttttc gaagaatcta ctcctggaac accgtgtatc agaggttgtg
    13681 aaagagacgt tcagccttga gcgatgataa aaactctcac aaacattgcg acgagtaacc
    13741 cacaggagca ataagaagcg attttgaaaa atagcttccc atatttcaca aaattatgcc
    13801 ttattgtcga tagcctgtct cttgaacgcc atttattcgt aaaaaagaac tgtgacaaga
    13861 cttttgtcac agttcttttt gcgtgcttag ccttgaaatt taactatcca taaatacaaa
    13921 tactagggtt attctaactt cttttattgc ttgaatcagt ccacaagaaa aacagcctct
    13981 tgattaaacg gcgtttatct tgttgattct gcggcaataa aatcagccag cagcaaaaca
    14041 tgaagtgctg ttttttgctg tcctctttta ttgcttgaat cagatcacaa gaaaaacagc
    14101 ctcttgattc acaaatattt ttttcgatat tctcccggcg taatcgattc cttcttttta
    14161 aagaaacgaa taaaattttg cggatttcga tattgcaatc tttctgcaat ctcttttacg
    14221 gagaggttag tctctttcaa ccattttttt gctacctcta aacgatgatt ttgaacaaaa
    14281 tcaccaaatt tttctcctgt ttccttttta aatacattac ttaaatagtt agggttataa
    14341 tgcaacctat cagcgatcac atctaaagac agatcacgat catattctgt gtagacgata
    14401 tgcataatat tctccgacaa atttttaaat tcatgatcag tgattgcttg agagcattct
    14461 gtgattggca gaactaattg ttctaaaaca agtttttcta gttctttggg atgataattg
    14521 ttcagtgctt ttacataaat ttgtttcatg ttatcaaagt tttttgaatc tactcccaat
    14581 aactgtccta attgaacgag ttcattgatc aagcggaccg aaactacttc ccgactcaaa
    14641 ggatttttat tttgtgcaaa caatgcatca atcaattcat gtactaaatt cttcacttcc
    14701 tgatttccag aacgaatggc ttcaaacaat cgattttgtt cttctatcgg atatctaata
    14761 agtgtttttt catgagcagc aggaacgatt tcctgataaa aaataattga acttggacca
    14821 gtatttacac gataatacag ggcttctttt gcccgatcaa ccgattgctt gctttcattc
    14881 agcgtttcga accggttact gatgcctata ctgatagtta aattcaagta ttcttttaca
    14941 cgtttttgaa tgagtcggca atactccatg acttttttgc ttgcttctgc atcatcttta
    15001 tccattcgat aaatagtggc ttgcatttct tcattcaaaa cgatcggcag cattcgattt
    15061 tcctttggca caatttccgt gatcatgttg ttgatcgcta aaagtagcaa atcacgctcc
    15121 ccaccgtgac tatcttctaa cagatcgatt tgaaccaaag ctgtataata gcagtcattt
    15181 tgagaactat aaccaaattg ctgcaaccgc tgatctagtt ctcgcctttc tactcgattt
    15241 ctaaataaac taagtacaaa tagcgtttcc agctgtggct tttgggtaac taagtgtgca
    15301 cttaacgctt ctttttctcc tatgatccga ctgactgatt gagcgaccaa atctagttct
    15361 ttcccactga atccttttga tttaagattc agacgttcct gtatttgaga aatcggacgg
    15421 gcaaatctgt ccgaaaataa gtaggaaaaa agaccaatga gtcctaccag tgttaaagac
    15481 actgcaacta gcccgattct cagattgcgg atcattgcgc caattgcact agagtcaact
    15541 tctaatctgt aaatccaatt attataatct gatttcagta ctatatacgt tttatctttt
    15601 tctcttatca ctttcagctg attgtaatct agatccacgt ccgttaatac agttggttgc
    15661 tctttatttt ttactgtctg agtagtaaaa aggttgccaa cttcgttttc aatagaaagt
    15721 atgtcttctc cactttcacc aacaacttgt tctattgtat gtttctctat cgtagcaatt
    15781 cccaatgcat atttttcttt ttcaaacatt ggcaaagaaa tcaccatttc gattcctttg
    15841 tttttctttt gccaaaataa attatttttg ttatttatgt acttctgttg atacttttca
    15901 acttcctctt cggtcagttg actcaacgat ccattgatta ctccccattt accagccaaa
    15961 ctgactaaat cataattatt atcatccata acaatcgttt ctataaaatt tagttctttc
    16021 ctgatttcag aataagtgga gtaatctgta tatgtcagcg gatgcttgaa tatgtccgag
    16081 aaatttttgg tcgaaccata cgtagaaaac gaatattcaa tcgttctaat tttccattca
    16141 acgttagttt taacttgcct gagcaaattc tttttgtctg ttaaataact cgattcgatc
    16201 gattcatagg tattctggta aatgaataaa ctaaatccta tgacaagtac ggctcctaat
    16261 aaaaacatcg gtaaaaatat tttataaaat actgtacttt tcttcatttt cttcctctcc
    16321 tccttttaaa ataaaaggct ttcatttttc tgtaaaattg atactcatct aattaaatga
    16381 gcattccccg ctttcaagaa tagcataatt aaaaataaaa atccaagtaa tttttaacgt
    16441 gtgcaatctt ttcatatcaa agatctattg acttatcgta gttatcgtaa tatgatgaat
    16501 gcgttaacaa aaagtgaaaa agtaaggaaa atgatggaat ggtaacgatc aaagatatcg
    16561 ctaaagcagc tggcgtttct catacgacag tttctcgtgc tttgaataac agcagtttaa
    16621 taaaaaatga aacaaaacaa aaaatacgac aactagctaa ggaaatgaat tattcgccaa
    16681 actatagtgc aaaaggttta gtgaatcaaa aaaaatatct aatcggacta tttttctcaa
    16741 gtttgcataa aggaacttca tcaaatttcc tagcagattc cattgcaggc atccattcag
    16801 tattagacac aaattacagt ttatctgttg aaagtatcga tgttgttgat ttaacagaaa
    16861 tcaacctgca acgctacgat ggactgatcg ttatgagtca aagtgatgat gatcagcctt
    16921 tcatcgacta tctcaaagaa aaagaatttc ctttcgttgt tgtcaatcgt cacatcaatg
    16981 atccagcggt tatcaacgtc actgccgatg atgcggccgg tgttatgcag gcagtagatt
    17041 acggtattgg atgcggacat acgaagatcg cttatattgg cggaaagaaa aattttcgtt
    17101 cgacaaaaga acgggaaaaa ggggtattga aaagtctaaa aaaagcgagc atccctgtca
    17161 atctagccta ttttttaaca ggagattaca gcttagaaag cggcctccaa aacatggaat
    17221 acctattatc actttctgac ctgcctactc tggttttttg cggcaacgac gacatagcga
    17281 ttggtgcatt gagagctgta catttagctg gcctccgtgt tccccagaac atttctctga
    17341 tcgggttcga tgattctcca gtcgtctcct atctcaatcc gccgcttacc accgtacgta
    17401 agcctttgaa agaaatgtgt caagaaggaa caaagctttt actagatttg atcgaaggca
    17461 ggacgatcga acaatctaaa attgagctct ccaccttgtt gatccttcgt gagtcgatca
    17521 attacttgta aactacaagt aattttatat aaaaatgtta acgtgtgcat aacacagaaa
    17581 ggaagtttat atgaaaaaac tgacaaaaga attagtgaaa aaaaacgaag cacctgtaaa
    17641 agttcttcag tttggtgaag gcaattttat gcgtggattt attgattggc agattcagca
    17701 gctgaataac caacaattgt ttaaaggtaa tgttgcaatc attcaacctt tagaacaagg
    17761 tcttggaaat atgatgaacc agcaagataa tttatatacg gtcattttac aaggactcag
    17821 caatggcgaa atcgttgata cttccgagat tatcaccgta gtagaacaaa tgatcaatcc
    17881 ttatgatgaa tgggatgctt atctatctct agcagaaaat gacgacttgg cctatatcgt
    17941 ctccaataca acagaggcag gaatccaatt cgtggagact gataatttaa cagatactcc
    18001 cccacagagc ttcccgggca aactgacagc ctttttatac cgacgtttca aattaaacaa
    18061 agctggcttt accatcattc cttgcgaact gattgacaga aacggcgaac gtctaaaaga
    18121 aatcatttta cgctacgcag aaaaatggga tttagaacct gcttttgttg agtggttaga
    18181 aaaagaaaat gttttctgtt gtagtttagt tgatcgcatc gtcccaggtt atcctcgcga
    18241 agatgcaggt gttttcaatc aacggcataa ctatgaagat caattgatgg tcaaagcaga
    18301 accattcatg ctttgggtga tcgaagggcc taaagaattg gagaatcaac taccattcaa
    18361 acaggctggc ttgaatgtca tcatcacaga tgatatgact ccttatcgtg aacgtaaggt
    18421 gcatttgctt aatggaccgc atacagcgat ggtccctctt gctttgttgg cggaattgga
    18481 aactgtagaa gaagtaatga aagatccttt attctccgca tatgttgatc agttattcaa
    18541 tctagaattg attcctatgc tttctttacc taaagatgaa ttagccattt atgctgacca
    18601 aatcaaagaa cgtttcttga atccttttgc ccatcacaaa ttagaagcga tttcattaaa
    18661 tagtgtttca aagttcagca cccgtctgct tccagtgttc aagaagtata tcgaagaaca
    18721 aaatcaggta ccaccgttaa tcactgtttc actagctgcg ctacttctta tgtatcgagg
    18781 cgatcaagta aagccacatg atgatgaaaa gacgataagc gaatttactg atgcttggtc
    18841 tgataatgga acagctattc ctcgattatt gcaaaacgct gcgctttggg gagaagattt
    18901 gtctcaaata ccgaatgtga cagatacagt tcaagaaata gctgcaaaga tcgatcaaaa
    18961 aggtgtccgg tcagtattac aagaaatgaa aggaacgatg gtccatgctt gaaaccctgc
    19021 aaccaacaat gaaattaaat cgacgagaca gtgtggtcgt cgcattaacc cctattccaa
    19081 aacaaacaca actgacgatt gatcagcaaa cgatcaccac tcttgaagat atcccgcaag
    19141 gtcataagat tgcattgggt gatttgaaag ctggagacaa cgtgatcaaa tatggctatc
    19201 caatcggtca tgtgacgaca gacgtaactg ccggtcaatg gctgcacact cataatgtaa
    19261 aaaccaatct ttctggtgaa ttggattatc gatatgaaaa agatgtccat ccaagtcatt
    19321 acctttttga gaaccgaaca tttcaaggtt acttgcgaaa aaatggaaaa gtagggattc
    19381 gtaatgattt gtttttagta cctaccgttg ggtgtgtgaa tggcattgct gaactgatcg
    19441 tcaaacagtt caaggaaaaa catccagatc tgggacagtt tgaccatatt acgattttaa
    19501 agcatcctta tggctgttcg cagcttggaa aagatcatca aaatactcga gaaattttag
    19561 cggacgcagt aaatcatccc aatgccggag gagttttagt atttggatta ggttgtgaga
    19621 acaatacagt tcctgaattc aaaaaaattt taggtgaata tgatgaagaa cgagtgaaat
    19681 ttctagtggc tcaagatgtt tacgatgaga tcgaacaagg tgtggctcta ttagaagagc
    19741 ttttaacagc ggcggaaaat gaccagcgca tatcagtccc gctctctaag ttgaatgtcg
    19801 gtttgaaatg cggcggttct gatggtctat cgggaataac tgctaatcct ttacttggtg
    19861 cattttctga ctacttgatt gctcaaggag gcagcacgat cttaacagaa gtgccagaaa
    19921 tgtttggcgc agaacaagta ttgatggcac gagcggaaaa tgaagaagtt tttgactcaa
    19981 tcgttgactt gatcaatgac ttcaaacagt atttcttgtc ttacggggaa ccagtttacg
    20041 aaaacccatc tcctggtaat aaagcaggtg ggatcactac attagaagat aagtctttag
    20101 gctgcacgca aaaatcagga agctctcctg tcgttgatgt gctacaatat ggcgaaaaaa
    20161 tcagaaaacc agggcttagt ttattgcaag ctcccgggaa tgatcttgta gctgcctctg
    20221 ctcttgcttc atccgattgc cagttggtct tgtttaccac aggaagaggg actccgtttg
    20281 gctcatatgt cccaacggtc aaggtatcta cgaatacaac tctttttgaa cgcaaaggtc
    20341 attggatgga ttttaatgca ggcgtcttat tagaacaacc aatggaagta atcttagaat
    20401 cgtttgttca aaaaatcatc gctgtagcta gtggagaaga aacgaaaaat gaacaaaatg
    20461 acgttcgaga aattgccatt tttaaaaacg gagtaacact ttgattttca taaaacagta
    20521 taaaaagaaa gaaggaagat ttatgttttt atctgatgat tttttattaa aagacgattg
    20581 ggcgaaaaag ctttaccatt cctacgcaaa aaacatgccc attattgatt atcactgtca
    20641 cttagatcca aaagaaattt acgaaaacaa caatttcagc aatctgacag aagcttggtt
    20701 aggaggcgat cattacaaat ggcgcttgat gcgagcttgc ggcgtgcctg aagaaaaaat
    20761 cacaggaaat gcttctgatt ttgaaaaatt tttagcttgg tgtcaaaccg taccaaaaat
    20821 tatcggaaat ccgctttaca gttggtcaca tcttgaattg aagcgtttct tcggtattga
    20881 cttgttgata aatgaagaaa atgcagagaa aatttggaca caagcaaatg aaattttggc
    20941 agctcctgat tttcgccgtc gggaaatcgc aaaaaaatcg aatgtagaag tgatttgtac
    21001 aacagatgat cccgcagacg acttgcacta tcatcagttg cttgctcatg aagaaccaga
    21061 tttgaaggtt ctaccttcat tccgtccaga taaagcactc aatattgaaa aagaaggatt
    21121 taatgcatgg gtcacactac tggaagaagc agctgaccaa acgatcacca cctatcaaga
    21181 actgatagaa gtcttagggc agcggataga atacttccat caacatggat gtcgtgtttc
    21241 cgaccacgct ttagacatct tacgctataa agaagcggat gaaacagtat tagaagagat
    21301 ttttcaaaaa gcacgagcta acaaactatt atcttcagat gaaatcgatg cttatcttac
    21361 agaaacactg atacatttga cccacttcta tcattctcat aattggacga tgcagctgca
    21421 catccatgct tatcgtaact gtaatacaca aatgttggaa aaattagggc ccgataccgg
    21481 ctatgatgga atgaatgatc tttctttgac tattcctctg caaaaattat tgaaccgtgc
    21541 agaagaaacg gatcagttgc caaagacgat cctttattca ttgaatccga atgactatcc
    21601 tgcgatttta gctttgatgg gctgtttcca aaaagaacag aatggaaaac tgcagttagg
    21661 ttctggatgg tggtacaacg atactcgagc tggtatgcgc gatcaattga cacaatttgc
    21721 tgatggtagt gctttgggga attttgtcgg catgctgaca gattcaagaa gtttcctgtc
    21781 ctacactaga catgaatatt tccgtcgtgt tctttgtgaa tttttaggcg aaatggtcat
    21841 gcgaggagaa gcacctgaag atgaacaact tttaggaagt ctagttcaag cgattagtta
    21901 tacaaatgct aaaaattact ttggcttttt tgcctaattg attaatagta acagtaacga
    21961 atcaaaaaca ggatagtgaa ataacggaat ccgtttatcc acgttttaga gaagaagacg
    22021 gaccaa
//
LOCUS       DAZULR010000042        20225 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.043, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000042 DAZULR010000000
VERSION     DAZULR010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20225
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.043"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            195..494
                     /locus_tag="ACG8ZV_001959"
     CDS             195..494
                     /locus_tag="ACG8ZV_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997272.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(591..1025)
                     /locus_tag="ACG8ZV_001960"
     CDS             complement(591..1025)
                     /locus_tag="ACG8ZV_001960"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4997273.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRGKKVLFGNDK"
     gene            complement(1257..1967)
                     /locus_tag="ACG8ZV_001961"
     CDS             complement(1257..1967)
                     /locus_tag="ACG8ZV_001961"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019569 - L-arabinose catabolic process to
                     xylulose 5-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HFS4997274.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(1957..2817)
                     /locus_tag="ACG8ZV_001962"
     CDS             complement(1957..2817)
                     /locus_tag="ACG8ZV_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HFS4997275.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(2822..3460)
                     /locus_tag="ACG8ZV_001963"
     CDS             complement(2822..3460)
                     /locus_tag="ACG8ZV_001963"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HFS4997276.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3475..3774)
                     /locus_tag="ACG8ZV_001964"
     CDS             complement(3475..3774)
                     /locus_tag="ACG8ZV_001964"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFS4997277.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKEVTVIGIKNVMSAKEISEKFAETKWYQKNK"
     gene            complement(3817..5301)
                     /locus_tag="ACG8ZV_001965"
     CDS             complement(3817..5301)
                     /locus_tag="ACG8ZV_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFS4997278.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQVLIFMGLILGCYWAVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPEGYFLIVEDYDTYAEKQRV"
     gene            complement(5321..5782)
                     /locus_tag="ACG8ZV_001966"
     CDS             complement(5321..5782)
                     /locus_tag="ACG8ZV_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFS4997279.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGEDEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(5800..6867)
                     /gene="ulaG"
                     /locus_tag="ACG8ZV_001967"
     CDS             complement(5800..6867)
                     /gene="ulaG"
                     /locus_tag="ACG8ZV_001967"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HFS4997280.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADSKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7085..7855
                     /locus_tag="ACG8ZV_001968"
     CDS             7085..7855
                     /locus_tag="ACG8ZV_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFS4997281.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8128..8955)
                     /locus_tag="ACG8ZV_001969"
     CDS             complement(8128..8955)
                     /locus_tag="ACG8ZV_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4997282.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9522..10757
                     /locus_tag="ACG8ZV_001970"
     CDS             9522..10757
                     /locus_tag="ACG8ZV_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFS4997283.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(11756..12016)
                     /locus_tag="ACG8ZV_001971"
     CDS             complement(11756..12016)
                     /locus_tag="ACG8ZV_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HFS4997284.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12043..13344)
                     /locus_tag="ACG8ZV_001972"
     CDS             complement(12043..13344)
                     /locus_tag="ACG8ZV_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFS4997285.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEKAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNATLLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPMIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(13636..14094)
                     /locus_tag="ACG8ZV_001973"
     CDS             complement(13636..14094)
                     /locus_tag="ACG8ZV_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFS4997286.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14107..14937)
                     /locus_tag="ACG8ZV_001974"
     CDS             complement(14107..14937)
                     /locus_tag="ACG8ZV_001974"
                     /inference="COORDINATES: protein motif:HMM:NF023401.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HFS4997287.1"
                     /translation="MINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYD
                     KELQREIMPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYY
                     LYPDMVVEHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDI
                     AISLLNDDRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVETITLRKPISDFHKGL
                     MEAQVAAEKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK
                     "
     gene            complement(14950..15437)
                     /locus_tag="ACG8ZV_001975"
                     /pseudo
     CDS             complement(14950..15437)
                     /locus_tag="ACG8ZV_001975"
                     /inference="COORDINATES: protein motif:HMM:NF014148.4"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
     gene            complement(15448..16890)
                     /locus_tag="ACG8ZV_001976"
     CDS             complement(15448..16890)
                     /locus_tag="ACG8ZV_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFS4997288.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAIFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSGFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGILFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(16877..17641)
                     /locus_tag="ACG8ZV_001977"
     CDS             complement(16877..17641)
                     /locus_tag="ACG8ZV_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HFS4997289.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(17745..18620)
                     /locus_tag="ACG8ZV_001978"
     CDS             complement(17745..18620)
                     /locus_tag="ACG8ZV_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFS4997290.1"
                     /translation="MKESASCFVLSYSGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAIEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(18875..18959)
                     /locus_tag="ACG8ZV_001979"
     tRNA            complement(18875..18959)
                     /locus_tag="ACG8ZV_001979"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18923..18925),aa:Leu,seq:caa)
     gene            complement(18977..19048)
                     /locus_tag="ACG8ZV_001980"
     tRNA            complement(18977..19048)
                     /locus_tag="ACG8ZV_001980"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19014..19016),aa:Gln,seq:ttg)
     gene            complement(19058..19130)
                     /locus_tag="ACG8ZV_001981"
     tRNA            complement(19058..19130)
                     /locus_tag="ACG8ZV_001981"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19095..19097),aa:His,seq:gtg)
     gene            complement(19192..19276)
                     /locus_tag="ACG8ZV_001982"
     tRNA            complement(19192..19276)
                     /locus_tag="ACG8ZV_001982"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19240..19242),aa:Leu,seq:caa)
     gene            complement(19297..19367)
                     /locus_tag="ACG8ZV_001983"
     tRNA            complement(19297..19367)
                     /locus_tag="ACG8ZV_001983"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19333..19335),aa:Cys,seq:gca)
     gene            complement(19413..19484)
                     /locus_tag="ACG8ZV_001984"
     tRNA            complement(19413..19484)
                     /locus_tag="ACG8ZV_001984"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19450..19452),aa:Gln,seq:ttg)
     gene            complement(19496..19568)
                     /locus_tag="ACG8ZV_001985"
     tRNA            complement(19496..19568)
                     /locus_tag="ACG8ZV_001985"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19533..19535),aa:His,seq:gtg)
     gene            complement(19571..19644)
                     /locus_tag="ACG8ZV_001986"
     tRNA            complement(19571..19644)
                     /locus_tag="ACG8ZV_001986"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19610..19612),aa:Trp,seq:cca)
     gene            complement(19651..19731)
                     /locus_tag="ACG8ZV_001987"
     tRNA            complement(19651..19731)
                     /locus_tag="ACG8ZV_001987"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19695..19697),aa:Tyr,seq:gta)
     gene            complement(19733..19808)
                     /locus_tag="ACG8ZV_001988"
     tRNA            complement(19733..19808)
                     /locus_tag="ACG8ZV_001988"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19773..19775),aa:Phe,seq:gaa)
     gene            complement(19844..19916)
                     /locus_tag="ACG8ZV_001989"
     tRNA            complement(19844..19916)
                     /locus_tag="ACG8ZV_001989"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19881..19883),aa:Asp,seq:gtc)
     gene            complement(19926..19998)
                     /locus_tag="ACG8ZV_001990"
     tRNA            complement(19926..19998)
                     /locus_tag="ACG8ZV_001990"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19963..19965),aa:Val,seq:tac)
     gene            complement(20014..20085)
                     /locus_tag="ACG8ZV_001991"
     tRNA            complement(20014..20085)
                     /locus_tag="ACG8ZV_001991"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20050..20052),aa:Glu,seq:ttc)
     gene            complement(20100..20188)
                     /locus_tag="ACG8ZV_001992"
     tRNA            complement(20100..20188)
                     /locus_tag="ACG8ZV_001992"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20152..20154),aa:Ser,seq:gga)
BASE COUNT         6337 a         4264 c         3209 g         6415 t
ORIGIN      
        1 aagacgcagt gttgacaatt gaaaaaaaat aaatgtttgt ataccatatg attatttcaa
       61 tatgtatcct ggaattggag atctcgtaga gctatatcaa gatgaatcaa atatacttgt
      121 cattcatcat gaaatataga gacttataaa attgtttatt tttataatgt atcagtatag
      181 aaaggaaata aaacatggat tatactgttg aatttgacag tgaactactt aagcaatttc
      241 cacaagaaga acatttcatg tataaagaag caatttccca caaagtgaca gagtatttgg
      301 agcataattt ttttcgtata aagccagtgc gtactcgttc ggcaaaagga atatacgaga
      361 tgaaagtcaa aattaataaa aaaaattatc gcatagcatt tgctttaaaa aaaaatcatg
      421 tgttcatttt ttatattagt tcgaatttgc aaaaaattgt atttgataaa gaggtgagta
      481 aaaaaataaa atagctgagc attggaggat agattgagtg atactaagtc tatcctcttg
      541 tttttctaaa gaactaagct agaatttttt cttttgtacg ttattatatg ttatttgtca
      601 ttaccaaaaa gcaccttttt tcctctagta tctatgacat aagaaatacc acccatttcc
      661 tttacttgaa caaatcctac tgattcataa aatttttttg ttttctcagt atcatctgtc
      721 aataattcga tttggactgg tccataacta gtgatcttct ccaaagcttc attcaaaagc
      781 actttgccta ttccttggcg ctgatacctc ggatgaatga ggatatcttg aataaatgcg
      841 atcgtcgcaa aatcagtgat ccaacgaacg attccgataa tcttcccttc cccattacgc
      901 tttatcagag attcagattg ttcaaatgct ctagctaacc ttgcagtgtc ttttgtgtaa
      961 ttcgtccaac caacgctctt atataattca gaaatctcat cgatcataag ggaatcaata
     1021 ttcatttttt tcttcctttc ttatacaatt ctccctctaa taatacagtt ctttgactat
     1081 ttaatctatc acatataact ctcctgtaaa gattctctcg attccttaaa atctctcttt
     1141 ccttttagaa tgcatccttt ttgataaata aaaaggttgt gataaatttt cttcacaacc
     1201 tctgtttctc tctatcaagt gttatctttt aattttctac ccttacccta gcatctctat
     1261 tgcccgtagt atgcatactt tccatgtttg cgaaaataat gtttatctag taaatattgc
     1321 gggatttcac atatattggg gttgatcagc tcgttttctt tggccatcag acaaatttca
     1381 tctaagatca aactgttttc tactgctttc ataggtgaat ccccccatgt gaacggtcca
     1441 tgtccataga caagtactcc agggacttcg tttggatcta attttctttc cttaaacgtc
     1501 tcgacaatca cattccctgt atgaacttcg taagcttctc ttacttcttc tttcgttaat
     1561 tggcgtgtac aaggaacctt accataaaaa gcatcagcat gagtcgtgcc ataagctggc
     1621 aaatcgcgtc ctgcttgcgc ccacatgacg gagtgcgtgg aatgagtatg agtaatagca
     1681 gttatatctt caaaagtttg atacaaaaca acatgtgtgg ggagatctga agatggtttt
     1741 aagctatctt cttctattat atttcccgac aaatctgtta ccaccatttg atctgcttgc
     1801 atgcattcat atctgacacc gcttggctta atgacgatga ctcctagctc acggtccact
     1861 tcactcacat tgccccaagt caatttgact aatccgtatc gcggcaatgc cagatttgct
     1921 tcaaggacac gttgcttcat tgctgcaatt ttttcttcac aagacatcat agccagcctc
     1981 cttcaattta gaacttaagt agtcttttgc ctgctggatt tctcttcgaa agtcttggct
     2041 tttttcactc cacatttcaa tcagaaatgt tccatcataa tctagacgtt tcaaatgtct
     2101 taataatcca agaaaatcaa cacaaccgct accaaaagga acatcacgaa actggcctga
     2161 atattctttt gttacagggt aagtatcttt taagtggata gcagtgatat aatcgatccc
     2221 tttctcaagt tctcgagccg gattattttc cggccatgcg gacaaattgc ctaggtctgg
     2281 atatacttgt agaaaagggg aatgaatctg ttctttgatt tctaaaaatt ttgaaatgga
     2341 gttcataaat ggatcatcca tgatttccac ggaaagaatg atgccatatt tagaagcttc
     2401 ctttacgctt tcttttattc cttcgataaa gtcttctctg gaattcattg atttctcttc
     2461 ataataaaca tcgtatccag ctatttggat tactttgacg cttagattat gcgccaaatg
     2521 gattgctttt ttcattagtt gtttcgctgc ttttttcttt tctggatcag cagaaccaaa
     2581 cggaaatcgc cgatgcgcac ttaaacaaat cgaatggata cgtacaccgg agctgaacat
     2641 ctcttctctc agctcagcta tcttttcttc agaccaatct aatcgtgcta accgctcatc
     2701 cgtctcatca atcgacatct cgataaaatc gaagtccatt tcttttacaa gggaaaaacg
     2761 ttctttccat gaaatatctt tgggtaatgc tttttcataa atcccaattt gagccatttc
     2821 cttaccccca gatacgaatg atctcatctt tgaagttttg tgcggccttc atcggatcat
     2881 ttgctgctgt aataccacga ccagtgataa aggtatacac atcgatccct tcaaataagt
     2941 gtaatgtgtg tggatttaat ccaccagtta cagaaacatt aaagcctagt tcaatcagtt
     3001 ttttgatctt cgataaatct ttttcacccc aagtttcacc agataacagc gcatcacggc
     3061 tttgatggta gattacctgc cggataccga tgttatgcca atccatggct tgttcaaaag
     3121 tccaattgcc gtagagttct acttgcaatt cacctatttc tttttgtgct gcctccatag
     3181 ttggaatcgt tgcacaacaa atgactgtca tccagtctgc tcctgctttt gcaacattac
     3241 tcgccactgt tcctccagcg tctgcacatt tcgtatcagc gactagtttt ttatctggga
     3301 acatactgcg aatacagcga atcgcttttt gtccttcctg taagcaaaga attgtgccca
     3361 cttcaataat atctactaca tcaccaactt tcataacatc tcctaatgca tgttctaagt
     3421 cattgtgatc taacgcaatt tgcaaattcg gcctgctcat cttagttcct tcctttactt
     3481 gtttttttgg taccactttg tttcagcaaa tttttcactg atttctttgg ctgacatcac
     3541 atttttgata ccgataactg taacttcttt tttctctgcc tgagtaaaca tattcaaaaa
     3601 attgactggc gtaaaaacta catcgtattg gccagctgaa ctttttccct ctgaaatggc
     3661 acaatgatgg attttggtaa ttggtacgtt tagttctttc attgcttttt ccacacttct
     3721 catcatcatc aagcttgttc ctgatccatt tgcacacgat actaaaattc tcatcttaat
     3781 ccctccatta tgagtgttgt ctaatcagat tttcttttat actctctgct tttctgcata
     3841 tgtgtcatag tcttctacaa tcaaaaaata accctcagga tttttccgat attgtaactg
     3901 cggaatagcc aataaaccaa tgacaactac ggcaattcca gcataaccta ggactttcat
     3961 gattactgta aacaatggcc aagctgttgc ccagtcgaac atcccgatat aaccaccata
     4021 tgttgacatc ccaatccatg tagcgaataa tgctgaaccg cctacttgta tgattcctga
     4081 aagaaacggg aacaggcaag cggctttgaa tccacctcgg ttattggcat aaactgctat
     4141 aacggcatta tcaaagaaca acggaatgaa accggctatg acgatcgttg gtgatttcaa
     4201 taaaatcagt aaaccaatca tcaaaaactg tcccaaagca ccaaacaaga acccaatcgt
     4261 taccgcattt ggcgaaccaa agccaaaagt agcagctacg tcaattcctg gaacagctcc
     4321 tggtaaaatt gtgtttgaga ttccttggaa agattgagtt agttcatcga cgaatgtccg
     4381 aacacctaat tgcaagatcg ccagatatac cgcaaaattt aaagaagtcg tcataatgta
     4441 gaataagaaa ctctgtcctt cttgcatgaa ttgcgcttga atcaaataat ctttgcctag
     4501 tacaatcaga atgatcccaa agaaaaatag catgagtaac gaagtagcaa ccatattctc
     4561 attgaaaatc gacaagaatc ctggtaattt gatatcttcg atttttttgt cttgcttgat
     4621 tgatctattt ttcttttcat cccgcttttt catccactca gctaattttg caaatataaa
     4681 gattccgaac atttgctgat gtgccactgc aaatccggca ccttctgtca attcctgcgt
     4741 gattcctact gttaagttag aagctactgc ccaataacaa cctaaaatca gtcccataaa
     4801 aatcaatact tgtatcctac ctagatcagg aaagcaaaac agtaaaatcc aaaaagcggt
     4861 agctgcttgt tgaacctgaa cgtttccggt agtgaaaacg gaacgcagtt tcgtatattt
     4921 ctgaaaacgg actaataaga tatttaaaac aaatgcaatc agtaataaaa tcatcacatc
     4981 tccaaaggta cggccaaatg tctccattaa tccagcatcc acagcatttt gtccaaaata
     5041 aggatctgta accatggcat ccaaattgaa ccgttccttt agtccaacca aaatcggccg
     5101 aaaattattg accaaaccac cagagccaac agtcaaaata aagtaaccga ccgttgcctt
     5161 taagaatcca gcgatgcatt catgaagcgg gcgtttcagc aaaatatagc ctaataacac
     5221 gataaaacca atcaggtatg ctggctgcgt caagatattt gttgcaaaat acgtccaaat
     5281 gcttaacaaa aattccccca tcttttttct cctctatcaa ttaattatat tctgccatca
     5341 caacttggta atcatcgatg gagttcgtag agatgagacg ctcaaccaat ccatctgtca
     5401 ttaataattc ggataatttt tggatatttt ctagatgttc ttctggatct tttgctgcaa
     5461 gtgtaaaaaa caaactagcc gttttctcct catcctcccc ttcactttca aaacggattg
     5521 gctgtttcaa cttggtaaat gaaatagctg ttccaaaaac accatcactt ttttctgaag
     5581 aatgcggcat tgctacttga ggtgcgatca caatataagg accgtatttt tctacacaat
     5641 ggatgatctc ctccacatac gtttcatcaa taatttcctt atcgatcaat acaagacagc
     5701 tttcggcgat agcttcacgc caatccgtga tttctttatc tgggtaatga atcaattgat
     5761 ggtcaaaaaa gtatttcagc aagaaactcc ccttctttct tataaaaacg acggaaacgg
     5821 tgtatcattt tcaatcgaga agacatcttc aaatcctcga taaaaattaa actcaagatc
     5881 atctttgttt gtcggataga tgaatttccc gcctacttgc cagatataag gtttaaatcc
     5941 atacttcagg cgatcctttt tgaatttcca aatttcagtg atctcttttg aatcagccat
     6001 aaaattagac caaatatcgt agtggacagg aatcactact tttgcattca atgactccgc
     6061 catgcgcagc atatcaacag aagtaacttt gtctgttatc cctcgtgggt tttcaccata
     6121 ggcccctaaa cagacatcga ttttgtgttc attaccatgt ttggcaaata aattggagta
     6181 atgtgaatct cctgcatgat aaagattccc tcctgatgtt tcgaataaat agtttactgc
     6241 aatttgatcc atctcctgag gcatttttcc ttttaatacc tcttctggat cttcacaagt
     6301 gaccaacgct gtccgatcaa acgcttctaa agctactaca ttgatgtctt tgattttgac
     6361 tgcatcacct ggctttactg taatcgtttt ttcttcagga attccccatt tttgccacgt
     6421 gcgaaccact tcttttggcc caatgaatgt tgcttcagga caattttgat gaactgctgc
     6481 ggctgtatgg atatctagat gatcggaatg gatatgtgta acgattaaag cgtctacatt
     6541 ttttatcgca aaaggatcga ttacgaaagg ctgagtacgt aaattaggct gcatattttg
     6601 aacgccactc atacgcatca tctgatggcc ttttttcatc atgccattcc catgactacg
     6661 ttttcccgtc ccacaccata gatcacataa aatattcgtt ccttcatgac ttttcagcca
     6721 aattcccgta cagcccagcc accacatagc aaaagttcca ggatccacta cttctgtttc
     6781 tatttcttca ttcaagtatg tgccccactc aggaaatgtt tctactaacc acttttcttt
     6841 tgttacttca ttgacagttt tactcatttg cttgctcccc ccatatcgtt gttccaactt
     6901 acaagtaaat attaatgtgt atcagcatcc atggaaaccc ttttatatga ccgtttgttt
     6961 tttatatgat tttctttcag taatcaatga ttgtttcagt ataataaaga cagatatgaa
     7021 tgtttaaatg aacaactagt caaataaatc catggatcaa gatgtccctc aggaggcaaa
     7081 agtcatgaaa aactcacttg tcaatattga aaaacgtcaa aaagaaattt tggaactgct
     7141 tcagcagact gaacaactat caactttcga attagctgaa tcccttgatg tatctattag
     7201 tacgatacga agagatttaa atttattaga agaaaaaaac gagatcatac gcaattacgg
     7261 ttattgttct tataattaca aaaaccagac tgattttgat caatctggtc ctgaaaggat
     7321 taaacaagcg attgccagag aagctagtaa atacattaac gattatgata cgctgtttat
     7381 caattctagc tcgactgcgt tgaaaacact ggattttctt caatctaacc atttgacagt
     7441 cattacaaac aacgtgaaaa tcaattactc tccgcacaaa gataattgta gttatatttt
     7501 aactggtgga gagatgcgct ttccaaaaga agcactagtg ggcgacatcg cattaaatac
     7561 gatttcttca gtcaatgcag acatttgtat cattggctgt agcggagtcg atgtagtaca
     7621 tggggtcaca acaaagatat taaatgaatc aacgatcaac gaaatgatgg tcaacaagac
     7681 aatcaaatgt aagattttag tcgctgatca tcgaaaaatc ggactgacat caaagttcaa
     7741 gattgctgat atttcagtct ttgattattt gatcactgat aaattttgtt ctgaaaaagt
     7801 attagaggag atcagaaata cggggataaa aaccattcaa gtagattcat tttaagaacc
     7861 aggacgtaaa tatgtaaata ggattatcaa aaaaatgaat aacaaattta tcgataaatg
     7921 aaaaacacgc tacgctcaaa ttgataaagg aatcccaaga tgtgtccatc caatcgatac
     7981 catcataatc tattgcttct tttataaccg ttatatgttg cctaaatagg aatcaaacaa
     8041 tatcgaaaaa aggaggtatg acaaaagtca cacctccttt tttcgaataa acggtattca
     8101 aatcagaaca ctgatttcac aaccacttta tttcaggtcg ttttcaatca cctttaccgc
     8161 gtaatcattt ccgttgaaac gcgctatttt ttttgcgtcc atatatcttt ctaaataatc
     8221 atcttctcct aattgcttat ggcaagaagc aatttcataa agcaagtatt ccaatgcata
     8281 agtcgattta tgtttcttat tatactcaat acccttctca cataattgga ttgctttatc
     8341 ataatcctcg attttacggt aataggtggc gatatcataa tatacaatgc agaccatcag
     8401 attatcaaaa tcagtctcac tcaatatttt aagtgtacgc tccacataaa ctttcgcaaa
     8461 atctaattct ccttttgaca agtagatcat tgccacgttt gcagctgctt gtaagtgatg
     8521 gatatctgtt tcggtcgttt gttccaacac ttgattaaaa taaaataatg ctgcatctgg
     8581 ttttttcgca taaagatgat caagcagtcc ttgataaaat aaaatttgat ttaaaagatc
     8641 agaattactt actttttcct gatcgatcgt ttgtaaaatt ttataagatt cttggtattt
     8701 tgatacagaa ttcaatgatt gaatctcatt tatttttttc ctgattttgt cttcttctgt
     8761 ttctactaat atatcggaga tctcgacatt cagctttttg caaagcgcac ttaagatatt
     8821 gatgcctggc gacatattct tgttttcgat attgctgaca gttgcttgtt cacaaatgcc
     8881 ttctgctaat tgtacttgtg ttaacccctt tttctttcgg tattctttta gtaatgctcc
     8941 atctacttta atcaaaacaa tttccttccc tttaaaaaat tatttctcct ttatatcata
     9001 cacaaaaaaa agttctaaac aaccaaaaat gtttagaaca gaataaaaat tttaatttta
     9061 aaataatatt caaattaaac aactggcgta tctgctcctt gatttctttt tgtgttatct
     9121 gaataattat cgtttacagt tataacacat agtgaaaatt gtcatggcga gaaagtctaa
     9181 gaatattttt aaacataact atttctttct tacgtgtgta taatgacgac agcacaccta
     9241 tcaattaata taattatttt attttttatg ttctcatgtt tatttttaat gacacaactt
     9301 ctcgtattta tctggcacaa catataaatc gatcaaaaaa ttgttgcgtg tttttttgaa
     9361 aattggagtt tcaacttgat tacaaaattt aaatttagaa gttgtgaaaa cagcgagaga
     9421 cagtttaata ttcaaaatat acataggcta ctcgaacgct gtgtttttta gtatactagt
     9481 aagaaacgaa gggatagact cattccaata aggaggattt catgaagaca attctttttg
     9541 ctcctgcagt attcaattta gctgagacaa cacgaatgat tgaggttgcc aaagctatga
     9601 aagaccgtta ttactgtgta ttctttggct tttctaaaac ttttgctcct ttgatcacag
     9661 aaagtggctt tgagtatcat ttactagcgc cgatccttac gaaaaaacaa gaagaacaaa
     9721 tcataaaatt tgaccagttg cgtacactta aaaacccttt taccaaagaa atggttgcct
     9781 ctcgtatcac tagtgaacag agtctgattg ctaagtttga gcctcgactg attgtgacag
     9841 gttcgaatgt gacaattttt ttatcggccc gcaataaaaa gattccttta gtatatgtta
     9901 aaccctatgc tttgagtgaa cctttttttc aatcagagca tgcgctgatg ccccacgagt
     9961 tacgtttctt cggcccttta agcaatcccc tttggcactg gacaaaaaag cgtatagtaa
    10021 atacccgatg gatccccaat gccttcaaac acgctgcaca aaaagaaatg cttcctttac
    10081 caaaaacaag tttacaaatg atggatgctg atctaaatct catcacaacg cctaaactat
    10141 ttttggaaga agaacagctg ccggaaaatt atcgaatcgt tggtccaatt tttgctaagc
    10201 tcagtacttc cttgcctgaa gaagtgctaa cttttataca gcgaaagcaa caagaaagaa
    10261 aacgtattat ctatttcgca atgggtagtt caggcaatcc gcgtatgtta cgcaaaattt
    10321 tgttcttctt acaaaaacaa ccggatctag cggttattgc acctattgac tatctgcttg
    10381 atgacattca atctgactca gaagatcttt taataacaga atatctgtct agtcatcttt
    10441 tgcatgaatt cattgatttt tcttttatcc acggcgggga agggaccgtc caaactgcct
    10501 gtgaatccgg caaaccgttt atcggtgtgg ggatgcaatt tgagcaaagc tgtaatattg
    10561 actattgtgt aaaatacgga aacgcaatcg ccctcacaaa accagtgact gaaagaaaac
    10621 tgcagattgc tctgcgcgaa gtttcttcac ccaagattcg tcagcaggca cgcacgctgc
    10681 aagccgtttt tccaataaat ggtccacaac aagcaattca agaaatcgaa accttcctga
    10741 gcaaccaccc aatatagttt caagtagaaa aagctttttt aatagagact catcagtaat
    10801 ttcgctattc gagacccaga cagtgaaaat acaaaaaaag taaatagtgg attgaaaagt
    10861 tagagttact taaattacgg tgtctaaaaa acacaaaatc atccttaaaa taaaagatct
    10921 gacgcaatcc aaatgagcat aggtagcgtc tgccatttat tcttagtcaa attctttgac
    10981 acctttctct ggttggatca tctcaacgtt tcttcaaaag aaagaccata ataattaggc
    11041 aaatacattt tcttaaaatg tgtcatatag atctagaagc atcgctttgt agagatttgt
    11101 gctgctagtc ccttcaacaa ttactaaatc aaatgtagga tttaccactt tatctttgat
    11161 aatcaacctc cctcttctgt tgagacaatg atctcgcaat ccgatgcata ctcctatata
    11221 aactgccagc aatccccaca tgctgagtag atcatgtcag aatgttctat gtcgtcagca
    11281 acgataaact aaaagtcacg ttcaccatga ctgattgcta ttcccagcgc aattatttct
    11341 atacacgttt catgatttga ataaacactc tcatcataca tattaccatt catacaccat
    11401 actgcagccc ctactatatg gttgtaagct cccaaatcta tatttgcctt gatcactttg
    11461 gtagtagatc gactaattct taatccattg ctgataaaat tttcattttt gcctccttct
    11521 ttctgccaaa acagttaaaa caataataat ctttatgtaa aaaagggctg tgacaaaagc
    11581 cttgtcacag tcccatattc cgaataaacg gtggtcaaaa gcttgcatct gcggtaataa
    11641 gttcaaccaa acgaaaaata agccaacatt tcacaaaaat ttaagaagca attttcgtaa
    11701 atttcttctt atttcttgaa gctaaccact tctgtcacaa ccacttttag aacatttaaa
    11761 gcttcgatgt gacaaaccat ctatgctgct cgatcataaa attgatagca aaaattccac
    11821 aaagtacata tgtcccccat gaaaacaaaa cattcatatg cggtacaatg atctttggaa
    11881 gaatcacgat caaaaatgat gccagtgccc aaatccatcg attgatttga atatgatatg
    11941 tagctagcat attcaatata aggtgactag ccgttaataa aaagataaaa acaaaaaata
    12001 aaatcagcca atacattgtt tcccaccttc taaaaaccaa acttagacag tttggacttc
    12061 gttttctcca cgactttgtt catctgacag catcttttta tcataagctt ttacaaatgg
    12121 ataatagata ataaatgcta tcaatgtgtt gatcatgatc aagataacaa cacgccagtc
    12181 atttcctgct gaaagataac cgccgattgg agctggtaat gtccaagttg gcaaaacagt
    12241 aaatctattg accatttcta atttgactgc aaaataactg ataatagtca aaactaaagg
    12301 aactaagttg aacgggatga acatgtaagg attcaacatc ataggagctc caaaaatcat
    12361 gggctcattg atattgaaga taccaggaat aatagaaaaa cgaccaacct ctttcaagaa
    12421 ttttgattta cagaagaata taaacaaaac agataccacg atcgttgctc ctgcaccacc
    12481 aattgttacc gtccattgat aaaactgttc aggagcgata tagggtaatt gggtggcagc
    12541 tgtaccatct gccaatgcct ttgcattctc atccaacatg atcagccaca ttggacgaac
    12601 aacagcccct acaatactca tgccatggat accaaatgac cacaacaaat ggatcaaaaa
    12661 cattggtagt aaaacaccaa gcaaattatt ccctaaaata ttggttaaag gctcgaataa
    12721 cgataataag gtagcgttta catcaaagcc cgcgacgctt cgaatcagcc aagtaattgt
    12781 taaaatgact gcacctggaa tcaatgcctc aaaactacgg gcaacagcag gtggcacttg
    12841 ttctggcatt ttgatagtaa tatttcgatt tttaaagaaa cgatatactt ccactgcaaa
    12901 aatcatagat aagatccccg caaacatccc agatgctccc aaagaactca taggtaagac
    12961 ccagccaaga ggtgcctttt caggagttaa aacgtttaca ggaacttgta acataaagaa
    13021 cgttcctaaa gataatatac cacctgtcac actatctaat ccatatgatt tagctagatc
    13081 cgaacccata acaaaagttg cataaatagc catcaatccc atcgtcatcc taaaaggtaa
    13141 aacaatcgtt gccgaataag gggcaataaa ttcattccat ccaggaaacg gtaaattgat
    13201 aaagaccata aaaaatgtcc caatcaaaat caatgacaat gttgaaacaa ccccattacg
    13261 aattgctaat aaatgacgct gtgtaccaat ttttgccatt ggtgggacaa gtttctcttc
    13321 gacccatttc atcagctttt ccactaaaac cactcctttt caataaaata tgaaccattc
    13381 attgcatgac aacgcaaaga atgttcataa ctaattatat aattaagaaa ttttatttca
    13441 atatattctc ttaaataatc aaatttattt ttaagaatcc tgaaaataag ttttctaaat
    13501 cataggagca acaaaaaaat tcgataatta acaaaaatca aaatgattaa atctagtgat
    13561 tgaaacttat catttcaaaa aaattttgta aattcaccca taaatatcac cctatttaac
    13621 ttttttcatc gtacactaaa attcaaaaca actatcttta atctttactt cttggttttg
    13681 ttttaataaa tttccttcaa aaatgcctgg agaaactaca atgatcaccg tatctttttg
    13741 tgcttgctcc aacttcttca aatctataat agctaacagt gtcccttctt ttacctcctg
    13801 gttactttca acccgtatct gaaacggact tccttcgagt tcaactgtat ctaaacccat
    13861 atggatcagt atttttctgc cagattcact ttcgatcgtt atggcatgtc gggtaggaaa
    13921 tatattatcg attattcctt taactggcgc atggatatat ccatcatgat tcgttatagc
    13981 gtatccaact cctatcattt ttgaagaaaa gacctcgtct tttactgctg ttaatggaat
    14041 aatttgacca ctagctacag cttttagaat gtttcttgtt ttaaagaaat gcacttttta
    14101 tcacctctac tttaatgctg gccaatattt tttgtttact ttgatcattt catctagtat
    14161 tttttttgcg actctggcat ttggtacggt ttgattcaat gtaaatgctt gtaaagcttt
    14221 ttgataagaa ccttcaaagt aagcatctac tagtaacttc tctgctgcaa cttgtgcctc
    14281 catcaatcct ttatgaaaat cactgattgg ttttcttagt gtaattgtct ccacaccagt
    14341 tgcaccaaca tatgccggta tttcaacaac tgcatctgac cgtagattcg gaatcgcccc
    14401 ttgattagga acgattagca taaagcgacg acgatcatca ttcaacaagg aaatagctat
    14461 atcgacgata tattgtccat gctccccaaa attaaagttc aatacttctt ccacaatacc
    14521 gcggcgtatt ttatcagcca tttctttggt atttttctct cgtccatcca tgaccatatt
    14581 agcacgtgta tactctttgt cagtatgctc aacgaccata tcaggatata agtaatactc
    14641 taagtaatta ttcgggatat tacttggaaa atttttcgtg atgactgaca tcatttgaaa
    14701 ggttttttgc caagttttgt ctcctatatt aaaatcggcg acttgcattt cttttgttat
    14761 tagtttttca ataatctctg gcataatttc tcgttgcaat tctttatcat aaatcgatgt
    14821 ataccagcca aagtggttta aaccataata cgtaacgatc caattcttac gatcataacc
    14881 gtaattcact gcaatcgttt cttcaattga aatagtcata tcacaggcat taatcatttt
    14941 tacattcgga tatttacgac gaacagcttc agaaacgatc gactctggat ttgtataatt
    15001 caaaatccat gctttggggg catagtcttg tatatgatcg acaatttcca ataaaccttt
    15061 gattgagcgc atcccataag caaatcctcc gagtccacac gtttcctgtc ctactaatcc
    15121 atgtttaagt ggaatctttt cgtccttttc tcgcatctcc aatcctccaa cacgaatttg
    15181 tgagaaaaca aaatcgcatc ctgtaaaagc aagctttgga tcatccgttg cacgaatgcg
    15241 aatatttgaa aaaccttttt tttcagcata aatttaacaa tcaagtacat atccatattt
    15301 ctttcttcat caatatcata taaacgtatt tcagataatg gcaaccgttt ttcattgttc
    15361 aaaatggctt gaacgattcc tggtgtatac gtactcccgc ctccagctat agtgataatc
    15421 tgttttttca tcatcatctt ttcctttcta ttcttctaat aatttattga attctgccat
    15481 aacataagtc acttctaagc cgatgataat ttgataattt ttttcagttg gtttaatgat
    15541 cccgcttatc cctaattgct tgattcgctg ttcctcgacc atggtgggat ccactacctc
    15601 tacccgtagg cgtgtattac aactatagac atccaggata ttggcttttc ctccaaacgc
    15661 ttgtagcatt tttgttgcca tatattcata atttttactt gctaacccta actctgtttc
    15721 ttctaaggtt acttcattgc caaactctgc cttagcttca cgtcctaatg tctgaatgtt
    15781 tctcttattg atcaaataat aaaaagtaac gtaatacaag gcaaaaaata aaattccgat
    15841 tggaagaatc aaaatagcat tggtagcgat tcgaaaattg atgagataat caacaataca
    15901 tgctccgaat gtaaaaccaa ttcgtatatt gaataagtaa cagacaatcc ctgctaaacc
    15961 ggcaaaaagt gcatggatca cgtacaacat aggagaaaga aacatgaaac taaattcaac
    16021 aggctcagtg atatttgcaa taaatgaagt tcctgcaccg cttcccatga ttcctttgac
    16081 catctcttta ttttctttat aagctgcttt atagatagct agacatatag ctggtatacc
    16141 aaacatcatt actacaaaaa aacctgataa aaacagtcca gcctgaggat ctccgttgat
    16201 aaagcgtgtc atctctcctc tgaaaacttc cttgctagga gatgtatagc ttcctaaatc
    16261 gtaataaata tacgtattca acacatggtg cagtccaaag gggatcagca aacgattcaa
    16321 aaacataaat atccccacac ctaatgcccc catatcaacg agcagttttg caaaattatc
    16381 aatcccaatt tggatgagcg gccagataaa gcccaaaaaa atagctgcga ttgtttgtag
    16441 aatcatcacc atagtcaatg ggaatttttc gcccgcaaaa taagaaaaaa ctactggtaa
    16501 tttttgttct ttaaagcgat tatacgtcca tgccgctact aaaccggaaa taattccacc
    16561 aaaaatcccc atattcactt ctgggtccat gatttctaag ccttttttca aggtagcaat
    16621 cgctaaaaaa ccagtaagtg caggtattcc tttgtcctta tttttgacaa aaccgattgc
    16681 aactcctata gcaaataaga tatccaagtt tccaaaaacg gcatttccag ctgcaccaat
    16741 tactgggatg ttcagcatat catcagctga taaacgcatg atcaatcccg ctaatggcat
    16801 cgctgcaact ggaagtagca tcgctcttcc aagcttctgc acatttgatt taacattcat
    16861 ttttattcct cctctattaa atatcctcat atgttactaa ctcaatcaaa ggatcatttt
    16921 tcactttttg agcaaatgct gaatgaatta aaaattcgac ttggtgagta cgaggataca
    16981 caaaacttga accatttaac aattcctgat ccaaatacgc tgcgtgacac atgacttcga
    17041 tcgttttatc ttctctcaat atcatgagta aacttgccaa atattcttcc acactcgtat
    17101 tgatttgtcg ttttttttca tcagtttctc ctacgacatc gaaacaaggc tcaaaataat
    17161 cgacatgacg aacttcatct tttcgttcaa agttgctccg aaccggcaaa tcatattttt
    17221 ttgctaatgt aacaactacc tcctggtttt catccaaagt atgagtatga tgatgactgt
    17281 ctaaatgagt tggtatgatc cccgcatgat aaattttttg aatctgagca ttccattcct
    17341 gatacagttg atctttgtca atgttaaatg gatgctgata ataagataag gatctgaact
    17401 ctccgctttc gataagagta tcgacagttt tgagaagtgg tttgccacac gtcaatgtta
    17461 aatggactcc tacacctagc ctaggcattt cctttcttag tttcacagcg tgctcgaaac
    17521 ccggcatatt tgccatcaat gtagttgatg tcaaaattcc tcgctgataa gcatccataa
    17581 tcccataatt cacaccatgg ctatagccaa aatcatccga attaaaaatc acttttccca
    17641 tttcattctc cttctttttt ctactaaaat aggcgcaacc aaataatcat agtccattta
    17701 ctatgtgtca tttggttgcg cctatagata gttacgccct tattttaata gattcgtgct
    17761 agatgaattg ccaaatagat gatttcattt tcttgaatgg caagttgaaa ttgctgttcg
    17821 atgatatctt taatctttag tgctgtacaa tacgctttgc tatgtttaaa tgtttcagta
    17881 aaaaaaccaa tattttctac tggcgtttct tcctgataaa tcaagcgttt aaccaggaat
    17941 ttgatatgaa ccattaagcg atgataagtc agtgattctt tatcataaac gtttgaatag
    18001 gatttttcta gatgggacaa aatcgtggtc gtcatttcta ctatttttaa gctctttaaa
    18061 ctattaggct ctcctagctc agcattaatg atatgcatag tgatgaatcc tacttcattt
    18121 gaccctaact cggtttgata tcgatgattg attcgctcga ccacttctat tgctatatca
    18181 tattcatttg gataaaggaa tctcatttct ggcaacataa ttgctgtgac atctctatct
    18241 tctctttttc gttgaatagc aaaataaata tgatctgtca atgtaatata gatatttgaa
    18301 tctaatggag aggagatcct agctgttatc agttcaatca cttcttccgc aaaatccata
    18361 aattcgattg gaatctgcga gactatctca ctgaatcgtt tgatcttttc tttagaatct
    18421 aatacaaata atttgtcagc atcctcaaca tcaaatggct tactcacttt agcagaaaag
    18481 ccaatccctt tccccatcgc aattttttct attccatcgt catcgatcaa tacagcatta
    18541 tgattcagct ttttcatcac atacaccgtt aattcacctc cactatatga taaaacaaaa
    18601 caacttgcag actccttcat acatattttt gtctccaaac aatttttaaa gacaaaaaac
    18661 gacctaagaa agaacccttt cttaggtcgt gcctaattga atagtagcac cctacataat
    18721 ttacaaaaat agtttaacac ataataaaag cgttatcaat atctttttta ctcgttttat
    18781 gataatactt gtatcgaatt gatttggagg taattacata aaaacaaaaa aaatatagca
    18841 actctctata agaaagttgc tatattgata attataccgg cggccggggt cgaaccggca
    18901 cgtcctcaac ggacactgga ttttgagtcc agcgcgtctg ccaattccgc cacgccggca
    18961 aatttaaaaa taataactgg ggtagctgga ttcgaaccaa cgcatgaggg agtcaaagtc
    19021 ccttgcctta ccgcttggct ataccccaag aataaagggc gaatgatggg aatcgaaccc
    19081 acgaatgccg gagccacaat ccggtgcgtt aaccacttcg ccacattcgc catcataaaa
    19141 gatgttattt aatttctcaa taaaaaacta agatgaagac atcttagtca ataccggcgg
    19201 ccggggtcga accggcacgc cctcaacggg cactggattt tgagtccagc gcgtctgcca
    19261 attccgccac gccggcaagt tgatttatta gtactaaggc ggtaaccgga tttgaaccgg
    19321 tgatgaaggt tttgcagacc tctgccttac cacttggcta taccgccatt atactattat
    19381 caatctacaa aataaagaat aaattataga aactggggta gctggattcg aaccaacgca
    19441 tgagggagtc aaagtccctt gccttaccgc ttggctatac cccaagaata aaaagggcga
    19501 atgatgggaa tcgaacccac gaatgccgga gccacaatcc ggtgcgttaa ccacttcgcc
    19561 acattcgcca tggcaggggc agcaggaatt gaacccacac taacggtttt ggagaccgct
    19621 gttctacctt taaactatgc ccctataaaa tggaggagag tggattcgaa ccactgaacc
    19681 ctaaggaacg gatttacagt ccgtcgcgtt tagccacttc gctactcctc catggtggcg
    19741 cgggacagaa tcgaactgcc gacacacgga gcttcaatcc gttgctctac caactgagct
    19801 accgcgccat attttaaaat tattaattga ataacaagaa cgacggttcc gacgggaatc
    19861 gaacccgcga tctcctgcgt gacaggcagg catgttaacc cctacaccac ggaaccagtt
    19921 cattatggag gttaacggga tcgaaccgct gaccctctgc ttgtaaggca gatgctctcc
    19981 cagctgagct aaacctccaa cattcaatta aaatgacccg tacgggattc gaacccgtgt
    20041 taccgccgtg aaagggcggt gtcttaaccg cttgaccaac gggccaggta aatttgctac
    20101 ggagagtaag ggattcgaac ccttgagaca gtttgcacca tctacatgat ttccaatcat
    20161 gctccttcgg cctctcggac aactctccag agtgaaagaa gctcaatact ctttctcaaa
    20221 atgag
//
LOCUS       DAZULR010000043        20003 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.044, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000043 DAZULR010000000
VERSION     DAZULR010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20003
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.044"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(16..714)
                     /locus_tag="ACG8ZV_001993"
                     /pseudo
     CDS             complement(16..714)
                     /locus_tag="ACG8ZV_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
     gene            793..969
                     /locus_tag="ACG8ZV_001994"
                     /pseudo
     CDS             793..969
                     /locus_tag="ACG8ZV_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
     gene            complement(1145..1714)
                     /locus_tag="ACG8ZV_001995"
     CDS             complement(1145..1714)
                     /locus_tag="ACG8ZV_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFS4997291.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1788..2111)
                     /locus_tag="ACG8ZV_001996"
     CDS             complement(1788..2111)
                     /locus_tag="ACG8ZV_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997292.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2265..3077)
                     /locus_tag="ACG8ZV_001997"
     CDS             complement(2265..3077)
                     /locus_tag="ACG8ZV_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997293.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3404..4279
                     /locus_tag="ACG8ZV_001998"
     CDS             3404..4279
                     /locus_tag="ACG8ZV_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010758089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFS4997294.1"
                     /translation="MGKRSTIQLMIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGT
                     FSRVQCTPDLLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLE
                     AMAENHATIDNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDD
                     ELLLLLDKFEKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAI
                     QLGISPRGSLSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKK
                     QIIHTLVAQIPIPVR"
     gene            4293..4616
                     /locus_tag="ACG8ZV_001999"
     CDS             4293..4616
                     /locus_tag="ACG8ZV_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997295.1"
                     /translation="MEKIKDYFINFVLFLVYFIIVLFALVFNNSLGWFLLAFFTLYVS
                     WSLISLSSFLKKLSVTCTLQPLVYRKKSMQVIFSIAKKRTFSLPLPRLQIGFPAIFAE
                     KNKRF"
     gene            4613..5365
                     /locus_tag="ACG8ZV_002000"
     CDS             4613..5365
                     /locus_tag="ACG8ZV_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HFS4997296.1"
                     /translation="MILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFRKSAKR
                     EISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNRIDWKL
                     SAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPELLILG
                     NRAFHGKDPGHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIETLSKD
                     RTAYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5355..7526
                     /locus_tag="ACG8ZV_002001"
                     /pseudo
     CDS             5355..7526
                     /locus_tag="ACG8ZV_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(7638..9809)
                     /gene="copB"
                     /locus_tag="ACG8ZV_002002"
     CDS             complement(7638..9809)
                     /gene="copB"
                     /locus_tag="ACG8ZV_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HFS4997297.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
     gene            complement(9829..12015)
                     /locus_tag="ACG8ZV_002003"
     CDS             complement(9829..12015)
                     /locus_tag="ACG8ZV_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFS4997298.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            complement(12015..12224)
                     /gene="copZ"
                     /locus_tag="ACG8ZV_002004"
     CDS             complement(12015..12224)
                     /gene="copZ"
                     /locus_tag="ACG8ZV_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HFS4997299.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(12237..12677)
                     /locus_tag="ACG8ZV_002005"
     CDS             complement(12237..12677)
                     /locus_tag="ACG8ZV_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HFS4997300.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQKGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(12751..13249)
                     /locus_tag="ACG8ZV_002006"
                     /pseudo
     CDS             complement(12751..13249)
                     /locus_tag="ACG8ZV_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation family protein"
     gene            complement(13534..15000)
                     /locus_tag="ACG8ZV_002007"
     CDS             complement(13534..15000)
                     /locus_tag="ACG8ZV_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFS4997301.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            complement(15311..17392)
                     /locus_tag="ACG8ZV_002008"
     CDS             complement(15311..17392)
                     /locus_tag="ACG8ZV_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFS4997302.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQETKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNELIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTAEGLMTVNPEDVLIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYIASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLVGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKQAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQSNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLSLGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            complement(17916..18275)
                     /locus_tag="ACG8ZV_002009"
     CDS             complement(17916..18275)
                     /locus_tag="ACG8ZV_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HFS4997303.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     AFLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(18305..18646)
                     /locus_tag="ACG8ZV_002010"
     CDS             complement(18305..18646)
                     /locus_tag="ACG8ZV_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997304.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERVGQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSIFAQF"
     gene            complement(18643..19317)
                     /locus_tag="ACG8ZV_002011"
     CDS             complement(18643..19317)
                     /locus_tag="ACG8ZV_002011"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFS4997305.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWREDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQKAGICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
BASE COUNT         5688 a         4217 c         3462 g         6636 t
ORIGIN      
        1 agaggggggg attttttatc gttgtggaat atttaaatac caacgcttgt catgaaaatc
       61 ttgtgctcca cccttagtat ttccttctgg atcgtttgtc gcacgcatca tgacgtatac
      121 tttcttatta gggaaatcac gcatattgaa agatacatga tagccaacat ttcctaaagt
      181 attataagct tgatttacgt ctggtctata aatcccatca gctcttactc tagctagttc
      241 ttttccagta ttgtagtcca taatgaaaat atactcgtat ttataattag caatgtgcca
      301 tccagctaca tgcaagtttg cgttttcgat ttctccgaac tgatcaatgt gggcgtaatt
      361 tgttccatct gtcagcgtag aatttgcagc acctgctcga gttggatcaa ttactggttt
      421 atcctccgaa gtagttggat tatcatccgt aaaaccatga gccaaatcat aggctagttt
      481 ttctttactt acacctattt cagaaagata accgtaagga tctgtatgat cgccccaaat
      541 attttgtgtt acccataaat gcgatttgat tcctggttgg ttataaggag tgtctaatgt
      601 taatggaata ccatatttca ttgctgaatc tcttgccaat tcaacgtata ctttatagtt
      661 cttttcaaaa gtttctttat catgtgtgtg ttgtaactcg atttgcacag gacttttggc
      721 tcacgaggtt gtcctactct acatcttgct gatagatatg ctgaaaggaa aacaccaaca
      781 ttatgttttg ctttttcagc tagaacgaga caagcaggaa tacctttaga agatatcaaa
      841 ggttttttag gtcataaaga tgtttccact acacaagtct atgcccatat ttctcccgaa
      901 gtgaaaaaaa gatcaatgaa tcaactagaa aactatatag aagagcaaat aaaaaagcac
      961 tcaaattgag tgctttttta agctcactat cactaaaact atcactaatt ttatttataa
     1021 gcgaacatgt ttctatcact gattttttaa atctagcgaa aaacccttat cttaaaggcg
     1081 ttcgttcaat tctttggcaa ggtcttcaaa gcctggcttg cctagaagtg cgaacatggt
     1141 tttcttatag ctcatgtaga aaaattttct tgatgatgat tttatccatc aattgagatt
     1201 gactgttttg ctctcctatg atttcagcta tgattgtccg attttgcggt tttcttctta
     1261 actggtagtt gattttccca gtttccatca actcgctaag catatccacg actccgccaa
     1321 atccggtctt tttcgtaata aaacctagtg ctaccattcg ttcatctaga ttttttgctg
     1381 taatcgtcac accagtaatg agcgagtgct gtaatgtttg ggccagctct tccatccctt
     1441 cagcattgga tacgacggaa gctgttttgt taataggttc ttcgtttatt tcttttggtt
     1501 ctttcctctc cactttcact gtttgacgaa ggacatctag ttcttgcaag agcgtttcgt
     1561 attgttcttg ggtcagcatc acgccagcta ctttttcacg attaaatata tatacgccag
     1621 ttcccgcgtc tcgcgcttga gcaaatacat ccatcggcga tcgtttcact tctgtgatcg
     1681 aagatgtggg aacttctaat ttctttaatt ccaatggatt tcctccttta ctaatcgctt
     1741 tttattatag cacagactga cttgttttga tcttttttcc aaaggtttta tcggtttttg
     1801 cctaaccagt aattgatatc ggtaagaagt ctttcgatac caaatgaagg atggtacaga
     1861 tacgtttttt gatcttcgtt atggtctagt ggaaaaaaat gatcgatgat cactagatct
     1921 gcataccgag gcggcttatt tcgagtacat acatgtatag agatccgttt tcgatgtctt
     1981 agcgttttgt tcagtacccc agcaagtctt cttgcttctt ggtgttcata gcgaaaaaaa
     2041 aagacgattt tcacttcagg agggtggaca tctaaatacc ctcgttcctg gagtgttttc
     2101 agtaaaagca tcccccactc tactgcgggg tgtgcaagtg cttgttggat cgctagccga
     2161 aattgatata gtttatcttt ggaattggga aatttttcta atgtttcctg ataataacga
     2221 acttcttcta tcagccggtc atggatacca attacgtaac gaagtcattc ttggtaaagt
     2281 acttttgtca gctttgattt gctttcgctc tcaaattcgc tattcagcca aaacagcgaa
     2341 tcaagctttt cagtcacaat cgtcaatttc cgatagtctt gtgtctcttc tatccgtttc
     2401 caccgctttt cagtaatctg gttacagctc aagcgcaaaa ttgctagata atttttttct
     2461 tttattggca aaatctgctc ctctctaaat agcaattcag gaaacaattc aaagaatagt
     2521 gttcgactgt ctcctaaaat ctcgatttct gccggatcct ttctttgctt caataattgg
     2581 atgaacatct cagaaaagga ctgctctcca tcatctgcaa aaaaatgcgg aaaatctttc
     2641 aaaaagcaaa acagcagata tcttactttt ctttctgaac caaagatctg tgctttttta
     2701 taagaaaaag aaaggtggta ctcgccaaac cactttctca atcgctcttg cgtagaacga
     2761 tcgtacttct gctcgtaagg ttcattcaat agcagatttt tcagtaaaca aaacgggggt
     2821 gattggatca gaaaaacaaa caagagataa ggttcgctat atccttgatc ataaactaac
     2881 tgaacggttt tcttatgaag aatcagctga atgggacagt cgctttccgc caaacgtttc
     2941 agatgccgat ccactgtttt aacatcgatt ttcagttctt cagctaaatc agcttttcgc
     3001 cagatcaaat ctttcattag attgattagt gaaaataaat tctgtgcatt ttttgataat
     3061 agtttttgcc atctcatcga tcatttctca cctgatttct aaacatattg tttgatcaaa
     3121 atgggttcac tcctaaaaag ataaaaaact ccctttctat ttatttaaat acgcaaatct
     3181 tcctcattat tttttatttt actcaattta atcgtattct catttcaaaa cgaatgtact
     3241 ttaaaaaaac ataataagat cactttgctt gtaggatgta ttcccttcca ttacaatgaa
     3301 ataaatagcg attttatgag aaggtgatgt gaaaatggaa gaaaaaatag aagaatccaa
     3361 acaaaaaatc gatcagttga tataagaatt agaaaaagcg gtcatcggca aacgttcaac
     3421 tatccaattg atgatcgtgg ccctattagc aggtggtcat gtcttattcg aagatattcc
     3481 cggtgtaggt aaaacgttac tggtcaaagc actagcaaaa gctgtacagg gaaccttcag
     3541 cagagtccaa tgtactcctg atctgctgcc tagtgatatt cttggttttt ccgtatacaa
     3601 ttcacaatca aaagagtttg aatttcgtcc gggaccgatc tttaccacga tcttgttagc
     3661 agatgagatc aatcgtacga ctcctcgtac tcagtcagca cttttagaag caatggccga
     3721 gaatcatgca acgatcgaca acaatacata ccctctagac aatcattttt ttgtcttagc
     3781 tacgcaaaat ccaatcgagt acgaaggaac atatcctttg ccggaagcac agctcgatcg
     3841 ttttttattc cgactacaaa tcggttatcc ttcttttgat gacgaacttt tgctactttt
     3901 ggataaattc gaaaaagtgt tggataactt aaatgaagta ttgaacagtt atgaaataga
     3961 agaaataaaa acaaatgtgg cgaatgtctt tgtcagtccc gaagtggcat cttatgcctt
     4021 gcagttagtg tcagcaacaa gaagtcatgc tgccatccag cttggcatca gtccacgagg
     4081 aagcctttcc tttattcagg cagcaaaagc ttatgcttta atccatggga gaaattacgt
     4141 cacgcccaaa gatttgcagg atttagttcc ttacgtgttt tcccatcgcc tgatttttta
     4201 cgatcgttca ttgaaggaag acgaaaagaa acaaatcatt catactcttg ttgcacaaat
     4261 tcctattcct gtgaggtaga ttgaggtaga caatggaaaa aatcaaagat tatttcatta
     4321 attttgtgtt atttctggta tatttcatca ttgtgctttt tgctcttgta ttcaacaatt
     4381 ctttaggctg gttcttgttg gcctttttta ctctttatgt atcatggagc ttgatttcat
     4441 taagcagctt tctaaagaaa ctttcggtta cttgtacatt gcagccactc gtttatcgca
     4501 aaaaaagtat gcaggttatt ttttccatag caaaaaagag aactttttct ttacctctcc
     4561 ctcgtttaca aatcggcttc ccagcaatct ttgcagaaaa aaacaagaga ttttgattct
     4621 tacaaataaa ccgcaagaag tccaattgct ttggcagcca aaagaaagag gatgccatga
     4681 aacattaact gtcattttta cagcctatga tagtctagga cttttcagaa aaagtgcaaa
     4741 aagagagatc tcttttcctg tgactgttct gcctgctttt tgtaagattc aagcagaaaa
     4801 attacagaga gttctggaaa aaaaacagca gctgaacgcg taccaaagag gtcttgattt
     4861 tcgggaacat cgcgcttatc gtccaggtga ttctttcaac cgaatcgatt ggaaattgtc
     4921 tgctcatact caagagtggt tataccgtga atacgattat caagaagaag aatgttctcc
     4981 tcttttttgc ttttggggtt cgcccagtcc aaaatttgaa cctctgctag acttgtattt
     5041 ttctttatgg catttgagaa aagaaaagca gccggaactt ctgatattag gcaaccgcgc
     5101 ctttcatggc aaagaccccg gtcataccta ttttgcttct ttggaagctg gcgatgagaa
     5161 agcttttttc gcacacttga aaaaatatgc aaaaaaacaa atcgtcctct ttgttcctga
     5221 gaattctcct gaagtctcag aagctattga aacattgtca aaagatcgaa cggcttatct
     5281 tgtttatttc gtagaaaaac aactcatggt ccaagaaaaa gacaagatat gttcattgcc
     5341 aggaggtgaa tggattgacg attaaacggg aaaaatggct gcgtggcgtt tactcctttg
     5401 tgatactaag tgtaggtgct ccgatatttg tagtagctaa tcaattgcaa aacagctacc
     5461 ttcttatcct aactattggt gtcctatgcc ttattgtctg ctgtattcct aaaaaatggg
     5521 tacgtttgct gctttctttg ccagtaatga taggttgttt gtttttatat tttccttcga
     5581 agacattttc catattatgg atcttacagt ttttttcgtc agttacagag gaattcttcc
     5641 atctatccca aggtaaactt tattatttgc cagaaaagac agcttttttt ctcataatgt
     5701 tgctgatcta tttatttatt acattgaccg tggattacga ctattggtac gcaccctttc
     5761 tttctttgat ggcttacttc atgatgctta ccgtttttcg gaaaaaagat ttactgtacg
     5821 aaatgattgc ggtagtaact gttttgttcg tgtatctggc agcaaggcaa tttttctcca
     5881 tccggttgtt gtcgggaaac actcgattcc agtcattgac tacagttctg cttatttgtt
     5941 tcttaacttt tagcgctatc ttgcctttat atcttccgaa agtacaccaa tctctcgagg
     6001 aaacgagtga accgatccga gaatatctta atgatgaagg gctttatgac acactccatg
     6061 agtatcaatt aaccggaagt gcaagaacag gcttcagtga gaatgatgaa cagcttggtg
     6121 gacctttata tgataatggc gaagttgttt ttacagcgaa ccaaaaagga aatggctatt
     6181 ggaagatcga aaataaaaat cattacaccg gttctggatg gatagaagat caggacgcac
     6241 ccatccaacc aatccaagaa ttccctgttg acatcacgag ctaccaaacc gttatagaag
     6301 acaaagaaaa cattacattg accctaaaaa aacaagcttt cttaccttat ccttatggaa
     6361 atactacctt gactgatttt tcattagcta gtggacaaac gctttactat ttgcctgaaa
     6421 gccagcgatt cattcctgtc ccgaatgaat cgacacgttc tgcaacttta caaacagaaa
     6481 ggttagtttt tacgagagaa gaattaaaaa gcagtcagtt aaaagctgat gatttagaaa
     6541 atcagcagac aaatcttcaa ttgccaaaaa gtttgcctaa acgtattgag gacttggcgg
     6601 tcgaattgac caaaaatgaa gcaactttaa ttcgtaaagt cgaagctgtc taacagtatt
     6661 taaaaacaag cggaaatttc cgctattcca aaacggatac cgggcatact ccgaaagaac
     6721 acgattatgt ggattatttc ctctttgatt caaaagtcgg ctattgtgac aacttttcaa
     6781 cttctatggt cgtccttctt cgaacacttg gtatcccagc tcgctggaca aaaggtttta
     6841 caaatgggct cagaacaggc acagataatc aagggaatga ggaatacagc attctcaata
     6901 gtcatgctca ttcttggcca gaggtatact ttcctggatt tggctggctt ccatttgaac
     6961 caaccccttc atttgccaat ccaatgggtt cacaaccagt tgctgaaaca accgaaaccg
     7021 tccagcctgc tatcgaacaa ccaaatgaaa gcgaaaatat ggcagaaact atttccagtg
     7081 agagatctga ggtcattcca tcagaagaaa caacactcac accagcttat aaaatcgtct
     7141 tattcagcct tggagtgtgt ttatccgtct tgttgttctt tctattgtta ttcagaaaat
     7201 ctctgcgctg gacaagttat cttatctatc ttcatttttt tgcttctact aatacgattg
     7261 catatcaaaa acttcttaac cctttggaaa cattggtacc gcgcaaaccc gcagaatctt
     7321 tgcaggaata tagcctgcga atagaacaag aattcaagct agatctgcgt ttcattcgat
     7381 taactactca atatgaagca gaaatatatg gacgacaagc agatccggta aaattcgata
     7441 aaaaaaccta tttagaaata acgcgtataa taagaaaaac ggtatacaaa aaaattctga
     7501 caaaagggag ccgcttcaaa aaataagata aaatttctgg agaatctact tctggaatgc
     7561 cgagaaccag ctgattgagt atcgattact cgaaaaaaag gttgtgacac gttttttgtc
     7621 acaacctttt ttcattatta tttgattttc aatgtcaaag catttagagc tacaactacc
     7681 gtacttaacg acatcaagac agcaccaact gctggactta atatgatacc aattggcgca
     7741 agaattccgg ctgctagcgg aattgcaaga atattgtaac ctgcccccca ccagaggttc
     7801 tggatcattt tctttcgcgt ttgcttggct agatcaagaa aatgcaaaat atcttttgga
     7861 tcgctgtttg tcaatacgac atccgcagaa tcgattgcga tatctgtccc tgcaccgatt
     7921 gccatcccga ttgaagcacg ggctaaactt ggcgcatcat tgatcccatc acccaccatg
     7981 attacttttt tcccttggtc aaggtatttc tggacaacag cttctttatc atctggtaat
     8041 aaaccgccat aatattcttc gatccctaaa taatctgcta ctgcttgggc agcgttttta
     8101 ttgtcaccag taagcatgac aggagtgatt tttctttctt tcaatgttcg gataaattct
     8161 tttgcttctg tttttactac gtcacctaaa gcaacgattg cagctagatg attttctaaa
     8221 atcaggaagc tgatggtatt tccttgttct tggtaaggtt tcaataatgc ttgttctacg
     8281 tttaatccga gacgctcaac ttctttttca ttaactattt tcacttgttg ttttttgact
     8341 gttgcctcta gcccgactcc tgaaagattt tttagatttt cagcttgata aggcttgatt
     8401 tcatgttctt tcaaataatt cataatgcca acagccaatg gatgattggc attcgcttcc
     8461 aaggctccta gatattgaag gatttcattt ttattgaacg catcatcaag tacttcgaca
     8521 cccgttacag taaattttcc ttctgttagt gttcctgttt tgtccagcat gatcacatct
     8581 agatcattgg cttgctccag tgcattgcgg tttttcaaaa gtaatccgtt tttagctgct
     8641 attgatgtgg agcgagcaac aactaatggg atagctaaac ctagagcatg aggacaggcg
     8701 atgataaaga ctgttaccat acgttctaat gcattaggaa gatctgtcaa gaacaaccag
     8761 gcgatgaatg ccaggatacc cacaattaat gcgacataaa acagccattt tgccactttg
     8821 tcagataatg actctagctt ggatttttct ccttgtgctt ttcgcaccat ttccataacc
     8881 ttcgctagat aaccattttc accagttcca gttacttcga tttcgatcgt tccatcccca
     8941 ttgatagaac cgccaatcac tttgtcattg gcttgttttt tgattcctct tgattcgcca
     9001 gtcacagctg attcgtcaac aattgtttca cctttcaaga ttacaccatc tgttggcatt
     9061 ttatcaccag accggacgat caaacgatca ccttcgttta cttctttcaa tgaaactgtc
     9121 tcttcttttc catctttcgt caagcgtttc actgattctg gcagtaattc tgctagtttt
     9181 tgtaaagcat tgctggcatt cgacacagca ttcatttcaa tccagtgacc tagtagcata
     9241 ataacgatca aagtagccaa ttcccagaag aaatccatga cgtgtgtatg tggattgagc
     9301 agatttgcga taaacgaata gacactataa atatatgcaa ctgtaatccc catcgcgatc
     9361 agtgtcatca tagcaggact tttttgtttc aattccatct tagctccact taaaaatggc
     9421 tgaccgccat agataaatag tatagttgct aagatcaata cgagccaatc agaaccagga
     9481 aacgttactt gaaatggaaa ttccattccc atcattggtg aaaaaagaat gattgggata
     9541 gctaggataa gcgatagcca aaatttttgt ttgaaattcc ccatgtgcat ggaatgatcc
     9601 atgccgccgt gttcgtgatc catgtgcatc gaatggtcca tttgtttgct gtttgctata
     9661 tctccatggt tatgtcccat gtgcatggaa tgatccatct gactatggtc atgtttcatc
     9721 tccatctgtt tttcatgaga ttctgtactt tctttgttta ctacttcttt tttatgctca
     9781 tgttttttct ccatatcgtt cccattcatt tttactccat cccttctctt actttttcat
     9841 gtgtcgattt aagctcaggg agttcaacaa tacactgacg gaactaaacg ccatcgctcc
     9901 tcctgcaatg attggattca aaaagcctag tgcggcaaaa ggaataccaa tcgtattata
     9961 gacaaaagcc cagaaaagat tttgtttgat ttttctcaat gtcaacctag acaactcgat
    10021 tgtttgtgca atggatgcca aactgctatt catcagcgtc acatcggctg tttccatcgc
    10081 aatgtccgtt ccacttccca ttgccatacc gacatcagct aatgctaagg ccggtgcatc
    10141 attgattcca tcgcctgcca taccgacttt tttgccatct ttctgaagtt tttctacgta
    10201 ggctgcttta tcctctggaa gtacttcagc aaagatatgc tttggatcaa taccaacttg
    10261 tttaccaatc gtttcggctg ccagtttgtt gtctcctgtc agcataaaaa catctaatcc
    10321 tttattctgg agctgcttga ttgcttgttt ggcttctagt ttgatttgat cagccacggc
    10381 aatccacccg atcacttgct tttcatcagc taaaaacatg actgtttttc cctgctgttc
    10441 taattctaac gcgtgttctt ggtattcatc aaatgatagg ttcaattcaa ttaatcgttt
    10501 acgtgtaccc gcaaaatagc gtactccatt aatcgtaccg ctgatcccag cacctgggtg
    10561 ggctgtaaaa tcaatcatat cgtatgttgc tgcttcttgc agttttccgt attccacgat
    10621 tgctttacct agtggatgtt cagaagcttg ttctaaagta taaaaaatag ataggacttc
    10681 ttttgaaccg actagatctg taactttggg ctttccttct gtaatcgttc cagttttatc
    10741 caaaacaatg ctgtctaagt gagcagctgc ttctaatgct tctccgcctt taattaaaat
    10801 tccatttcgt gcaccaacac ccgttcctac cataatagct gttggggtcg ctaaacctaa
    10861 tgcacatgga cacgcaatga ctaatacaga gacactatgg atcaatgcga gttgccaatc
    10921 accagtgatc aaacctgtag ctatgagcgt gataaacgcg atgactaata cgatcggaac
    10981 aaaaatccct gagatccgat ctgcgatttt ttggattggg gctttgctcc cttgagcatc
    11041 ttccaccatt tgaatgattt gcgctaatac tgtctgcttg ccgacttgtg tgacttccat
    11101 gtgtagcaga ccattcgtat tgattgtccc gccaaaaagc gtgtcatccg gattcttttc
    11161 tacaggaaga ttttcaccag taagcatact ttcatctatc gcactgcttc ctgaaataat
    11221 tcgaccatct gctggaatct gctcaccagg acggatgact agttgatcac caacgactac
    11281 ttcttcaatc gctaacgttt cttctttccc gtttcttatc acttgggcgg tttttgtttg
    11341 aagagacatc aattgtttga ttgcattacc tgttttcgtt tttgctgtat gttccaaata
    11401 tttgccgagc aaaatcagcg tgatgatcat actgctgctt tcaaaataaa gatcttgggg
    11461 gtgtccacgg aaaaatccgt tgtaaatgct caatgcaaag gcagccgatg ttccaattgc
    11521 taccaataca tccatatttg gtgctttcgt cttgattgca tggtacgcac ctttataaaa
    11581 acgagcaccg acataaaatt ggacaggagc agacagcact aactggacga ttggaaaatg
    11641 aaaaaagtga acaatcgccg catggcttcc taacatcata gcaatcattg acaacatcaa
    11701 cggcaaagtc aaaaccgtac tcaatataag atcgaatagc atttttttca aatacgcttg
    11761 cttttcttct gcaatttttt gtttgtgggc ttcatcgtac aaaattgcac cataaccgat
    11821 gttttctacg ctttggatta atttttcagt ggtcgtccct tcatatttga cacttgcttt
    11881 ttcagtggcc aagttgactg tggcattgac cacaccaggt tgtccgttca gctctttttc
    11941 gatcctagca gaacaatttg cacaagtcat acctgtaatg acgaacgtat ccattttggt
    12001 ttctgctgtt gccatcaaat cacctctgct ttataaccca atccattgat tgcttgacaa
    12061 atcttttcgg attgaacttt tgtttcatca aacttgaccg taccgtttgc ttttttcaaa
    12121 tttactttca ctttttgcac gccgtcaagt gcgcttactg tttcttctac tcttgctgca
    12181 caatgattgc agctcatacc ttcgattgaa aattgttgtt tcattttttc ttcctcctat
    12241 tgatgttgtt tacattcaca ttgacctggg atacagttac attcgatcgt atctactggt
    12301 tgcttttgtt ccagttgttt caaaatctca ttgatatctt cttgagtcaa agtagcttct
    12361 tctactagat ccgcaatcgt ctctccaatc ctttttgcac agatatggga aaaaagattt
    12421 tccgtcgcac tgcgaactgt ttccatctcc gagacagctg gatgataaat gaattttttt
    12481 cctttttgtt ctgtccagat cacttctttt tttaccaaac gtcccagcaa agttttgatc
    12541 gttgctggtt tccaatccat cgaatcagct aagatctgcg tgatttcttg ggctgtcgtc
    12601 tgtccaagtg tccaaataac acgcatgatc tcccactctg aatcactgat ctttactggc
    12661 gttttgactt tttccattta tttcacacct ttcgtttaca aatgtaatca ttagcttatg
    12721 aatacagatt acgcttgtaa acaaaaactg tcaattattt ttgctctcta ttttcaattt
    12781 agttaaaaat tcttgtttct ctcgtcttgt tttaaggatg atcagtttat ttcttgcatt
    12841 agctacttgg atcagctgct gtatttttgg ttcattgttt ccttcaaaat gccagataaa
    12901 agataaaaat tctaagtatt tcctgtttag tttctccgaa aatgattcag gcatatctgg
    12961 ccgagatttt ttgtttatct ttctttttag agaacgccaa actactcggt agatggcgag
    13021 ataacgcggc actttaagcc aaatgatctt atctgcttct ttaatccttt cctctaacgt
    13081 agaagtataa tttccttcaa cgatccatga cggattagat actataaacg attgctgttc
    13141 ttgcaaaaac cacttttttg cctgaatgcg gaaagccggt gatttctttg atcttccttg
    13201 cgagggacga ttttcccgac ccactttgtc caatcacgat gatcttcatt cttctccctc
    13261 acttctcttt ggaatttggt tcgatcatac cacttataac gccgcaaaaa aacaagggac
    13321 tgtgacaaaa gtcgtgtcaa agtcccttgt ttcgaataaa tggtgttcaa tcagctgacc
    13381 ttcagcatta gctcaaaaaa cggcaaaata tgaggagcta tttttgtttg gctgttctta
    13441 ttacttgatg caggacagct ttttcacaac ctctgattca cggtgttcca gaagtagctt
    13501 ctgtcacaac ctcttgtaac aagtatttct attttaaggc tgaaccactg tttctggttc
    13561 agtaatttct ttgtttttgt ctcgacgagc aattgctggc aagatcatac ctaataagat
    13621 caagacaatt ggtgtgatga tattcgtgaa taattggaac caccatgctt taggatcagc
    13681 agtataatct acttttggca ccattcctag gatacatgca aacgcagtga aggcaaagca
    13741 ccaagcacca aagataaaac cgatttttgg atttttaaca aatttatatt cagaattgaa
    13801 tttcttataa gctttattca acatcatata tgccaagaac acccataggt aacgcattgg
    13861 catgacaact gagttcaagt tcgtcaacca ttttactaat tcattcatat ctttgatacc
    13921 aaagatcggc aacaaaataa tgattcctac tagtatacct gtcagaagat aaccattcac
    13981 caatgtacct ttacgattac gtttacgtag ccagtttggt acaaattctg gatccgcatc
    14041 tgctaacaag atttttagtg gtgcatcaat tgaaaaggct aatgcggaga tttgtccaat
    14101 catgtttgtc aatgcgtaaa tgatcatcaa tgagttaccg ataccatagt aattacctaa
    14161 aatttgaaaa gcactgtatg ccccatttgc catcaagtct ttagggatat tatcgctagc
    14221 aaacagcata cccattgcga ctgagcctaa tacagcacaa atccctacca ttgctgctaa
    14281 gaagatcatc cctttaggaa attcctttgc aggatttctt gtagagttga cataagggga
    14341 tattttttcc gcccctccaa ctgcaaatac tagcatcgaa acggttgtga aataactgaa
    14401 atcaaatgtt ggaatatatg ttttcacttg attcatatgt ggtgtggcaa attccatcgt
    14461 tggattgatg aacggtgccg ttacagctaa aagaataaat aagatcgaca tgacgaacat
    14521 cgctgttccg gccagtccgc caatcacttt caaagtagaa agtccttttg ttgataaata
    14581 taaaaaggca agaaatataa taagtgaaat aactgctacc atttgtactg acatcgtatt
    14641 tacgatattt ccatttcctt ggactgccca accaccagca atcagaattg cttgaggctt
    14701 ttgtgccaaa taaggaatat ggacgaccca gtaagtccaa gcggcatagt atgccagtcg
    14761 tttattagat gtcgtatttt cgacccatga actgacgcct cctttactat ccttgaaggc
    14821 tgatcctaat tgtccaacga tcaatgcgta tggaataaaa taaatggcca aaatcaatag
    14881 ccaagaggtg acaactgata ctccttgctg agcatagtta ttaactacat tccccatgcc
    14941 ccaaaccatg ttaaatgcaa ttaacgcaac agtaaaccag cgtaattgtt tgttgttcat
    15001 tcgttctctc ctttatgata aaaatttgtt atccagatgt aatcatattc aatttttaac
    15061 aaacttacaa gacagtgtta ttttatgtgt gtattatttt atttaataca catcgttttt
    15121 tcatattttt tccatcaaaa aaataagtta ttttctttta tttcattgac cttattgaat
    15181 ttcaagctat tttgaatttt ctgcaaaatt aaaaacatta gttattttat aatcctatct
    15241 attttcttta catttttcat taagaaaagg atataaaaaa aagaggacgt tcattcgtcc
    15301 tcttcattga tcaacgttta ttttttacat gcaagcttcg catggcattc aaaacagcta
    15361 atactgtcac cccaacatct gcaaatactg catctcccat tgatgcaaaa ccaaaagcac
    15421 ctaaggaaag taccaaaatt tttatcccaa tagcaaagac aatgttttgt ttgacgattt
    15481 tcaatgtttt ctttgctaaa tggattgctt ctgcaatctt cgatggttga tcattcatga
    15541 tgactacatc tgctgcttca attgcagcat cgcttcccaa tccacccatt gcgattccta
    15601 catctgctct tgctagcacc ggtgcatcgt tgattccatc tccgacaaat gcggtctttt
    15661 tattgttact ttgtaagatt tcctctaacc gctgcacttt atcttctgga agcaattcgc
    15721 tatatatctt gtccacgcct acttgcttcc cgatatgatc agcaattttt ttcgagtcgc
    15781 ccgtcaacat gactgtgttt ttcacaccag cctgttttaa ttgaaccaat gcgtctacgg
    15841 catcttcttt caaggtatct gcaataacaa gataaccact gtaactttga tcgattgcta
    15901 gataaagcaa tgtaccgatt tcttgacttg aaggaaaaga gatttcaaat ctttccatca
    15961 atttgtgatt acctactaat acttgtttgc catcaacttc agctaagatc ccttcacctg
    16021 caaattcctg gatattagct gttggtaaaa gcggacctgc gtagccttct aaaacagatt
    16081 gagcaatcgg atgtgtagaa aactgttctg cactcgcaat atattgcatg aatatctttg
    16141 gatcgatttt tgtatcgatc gtctggatcg aaaagtcgcc tttcgttaat gtgccggttt
    16201 tatcgaatac cactgtctcg gtttgcgcaa gcaactccaa gtaatttgaa ccttttacta
    16261 atacaccgat tttacttgct cctccgatac cgccaaagaa actaagtggc acggaaatca
    16321 ctaatgcaca tggacatgag atcactaaaa atgtcaatgc tcgatagatc cattcagaaa
    16381 acgccgctcc agaaacaaca agtggaggta aaacagctaa taaaacggcc aatcctacaa
    16441 cgactggtgt gtaatagcgc gcgaatttag taatgaaatt ttcagctggt gcttttttac
    16501 tgctggcatt ttctactaat tctaataatt tgctgatagt agaattttca taagattttt
    16561 ctacttgaac taaaaatggt ttatttttat tgataaatcc gcttaatact gtttcaccaa
    16621 catatacaga tttagggact gattctcctg taagtgctga cgtatcgact aatgattctc
    16681 cttcgatgat cgttccatct aacggtacac gttcaccagg cttcacaagt acaaactgac
    16741 cgatcagcac gtcttcaggg ttcacggtca tcaatccttc cgccgtctgc acgtgagctg
    16801 tttctggacg gatcgccatc aattcgcgaa tcgattttct tgaatgactg actgccaatc
    16861 cttggaaata ctcgccgatt tgataaaata gcatcactgc tacggcttct ggatattcac
    16921 cgatcaacat agcgccaatc gtagcaacag acataagaaa attctcatca aagatttttc
    16981 ctttgacgat attcatcact gccttcttca ctacatcata tcctatcagc agataaatca
    17041 ataaataccc tatcaagcga attagttcat taaaatcaaa taatagcaat aaagcgatac
    17101 ctgcaaggga aaataaaatc cggaacagcg tatttctctc tttttcattt ccatgttcag
    17161 atactttttc cttatctatt tctgttactt tgacatctgg ttctaattcc ttcactactt
    17221 tttttgtttc ttgttcaatc gtagccaaat gatcttcctc cgcgtcaatc gttagttttc
    17281 cagaagtgaa gtttaccgtt gcttccttga ctccattgat tttctgaact cctttttcga
    17341 ttttcattgc acagttcgca caatctaaac cttctaatct gtaacttttc attttaatga
    17401 cctcctcgcc tcaacatatg aatatctctt cataactaat tataaatgaa tggttattca
    17461 tatgtcaagg tatccgaaag aaaaaatgaa aaacatctgc atcggaaaat ttcttccata
    17521 cagatgtttt ggcttattct ttctttttct cttcgatcat tgccactgct cttatccaac
    17581 ccgcacttgc cttcttgatc ttgacaggat agcaactaag tttgaagcct gttgctggca
    17641 atttgtctaa attcattaat ttttcgatag gacaatatct tttttcaatc cctgcaaaat
    17701 gtccttccca gatatacgaa gctccactac gctttcaaaa atatagaaag agttctttaa
    17761 tgaaaattat ttcaactttc cataaacagt aaccccatat aaataaaaga cgtaaaagtc
    17821 acatggaaga acttatacag gaaaacgcat agagtcaggt gaaatacatg tatcccacct
    17881 gactctatgc tttatctaac ctttattatt ctcttttata caatttctgc accgaatggc
    17941 atcaacgcca atcgagcaag tttgaaagat tgcttggcaa aaggtatccc tatgatcgtg
    18001 atacatagaa ggatgccgct gacgacatgt gcgagagcaa ttggtaggcc tgaaacgatc
    18061 agccagatga tattaacgat caatgacatg ccagactggt gataaattac ttctttgcca
    18121 aaaggcgcaa aagaaaggaa ggcgatctta aaacattgca taccgattgg gatacctatg
    18181 atcgtgatac accaaagtat ccccgctgct aaccagctaa gaccaccgat tagtccgccg
    18241 aatataaacc agatgacatt tcctaaacaa ctcattgtat ttctccttct attactgttt
    18301 ttgattaaaa ctgggcaaaa attgatttta ttcttctttt tttagcttcc agcatcaaat
    18361 attctgcaaa ttttttttgg atttcttccg tattttcttt tgttactaat gtgtgttgga
    18421 ttagttttcc tgatggtcgc tgacccaccc gttcttctga ctgttgcacg tccgcttgcg
    18481 caaaaccgat aatccgtttt tcttttgtta cagcaacgag caatagttta ttcttatcat
    18541 ttaggtcagc tgccgttttt gcttttacga atgattctgg atgatcagta atcagctgat
    18601 tgatttgagg tagatcttct tttactgccc accgtatttc catcatttct cacttttctt
    18661 tcgctcattt ttatctccac taaaaaaatc gactgcggca attgcatcta tccagctttg
    18721 tgcaatgatc tcatgtccgc caatcgttgg gtggacccca tcttctcttg tatatttcga
    18781 aaaaccataa gcaatcccta aagcattgaa tatgccatct aaaggaacca gcaatgcgcc
    18841 atattcctta gcaagtttac gaacaatttg gattttaggg tctaagtctt tacgccagcc
    18901 atgacggtcg tcggttatag gaagtacaaa cggctccatc aagatgatgt tgcagattcc
    18961 cgctttttga agttcattta gtaattttcg ataaacggat tcaaattgct gagcagattt
    19021 ctcagttccg aatatagcct gatcgctagt attatgccag gtatcattga ttccgatcaa
    19081 aatcgataca tagtcaggtt gtaaagctaa acaatcttct cgccagcgta cttgcagatc
    19141 tgcaattttg tctcctccta tcccacggtt catgcattca aattccatcg ttggatattg
    19201 ggagattagt tttccggcaa tcaaaagtgg ataaccttta cctagatcag ttgcttctgc
    19261 tcggtctctt cctgcgtctg taatgctgtc accgataaat aatatacgtt ttttcatttg
    19321 tcaaaaactc ctttttgaat aaaacgatga ttttcttcct tatattatcc cataagccct
    19381 atcaagacga aagagaaaat atatgtataa aaaatgacac cagcctagtc ccttcaaaca
    19441 attgaatgaa cgctcatcaa gtgtctagtt ttttatgcta tttttttctt aacgtgctgg
    19501 attccccttg attccttcat tgtttggtcc agagagatcg atcacaccta agcttccgtc
    19561 aatcagacca cttgatgacg ccatcagaac atatatttat aggctcatct aagacttcca
    19621 gtaaatgttc ctttactaat atctcttcta gattgcttgg gatagattgg ccataacttt
    19681 atctggtccg atgatttcaa gggtgaattg aacttacata tggatcattg catgctgaaa
    19741 atacggacct actccatctt cgaatgttac tattagtttg ttttcaggtg ctagatgctg
    19801 ctttatttca acagcagaag catcatcaaa tcagatttcc atttgaataa ccttctttgt
    19861 atatgtttga ttgattgcga tttcgttata gaaccttgtg aatcaaatag caatttcttt
    19921 tgctttcttc tcttatctgc tggaaacttc ctttatcccg tatttaaaaa aaaagaactg
    19981 cgagagttcg cagttctttt ttt
//
LOCUS       DAZULR010000044        19191 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.045, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000044 DAZULR010000000
VERSION     DAZULR010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19191)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19191)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19191
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.045"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            647..964
                     /locus_tag="ACG8ZV_002012"
     CDS             647..964
                     /locus_tag="ACG8ZV_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HFS4997306.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNSSIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(1055..1420)
                     /locus_tag="ACG8ZV_002013"
     CDS             complement(1055..1420)
                     /locus_tag="ACG8ZV_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997307.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1628..2110
                     /locus_tag="ACG8ZV_002014"
     CDS             1628..2110
                     /locus_tag="ACG8ZV_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997308.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            2307..3197
                     /locus_tag="ACG8ZV_002015"
     CDS             2307..3197
                     /locus_tag="ACG8ZV_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042301 - phosphate ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HFS4997309.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
     gene            complement(3484..4758)
                     /locus_tag="ACG8ZV_002016"
     CDS             complement(3484..4758)
                     /locus_tag="ACG8ZV_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1476 family transposase"
                     /protein_id="HFS4997310.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSS
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQAILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMNSVSGSMSFICVDGTTNQLFTILEDRRLYKLTQYFLRFPRKARLKVKYLV
                     MDMNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQIMNRFRTSHSENQKKYR
                     RLKRYWKLLLKDSTTWEPLKRHYHRLFKRPISQTEIVDELLSYNEELRTAYHFCQLLR
                     YYFVKRGTEGFQETLKTISSTLPQSFKKKFTIFHCYQSGISNAFKVSHSNGVTEGLNN
                     KIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
     gene            5031..7502
                     /locus_tag="ACG8ZV_002017"
     CDS             5031..7502
                     /locus_tag="ACG8ZV_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFS4997311.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(7605..9341)
                     /locus_tag="ACG8ZV_002018"
     CDS             complement(7605..9341)
                     /locus_tag="ACG8ZV_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFS4997312.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSVFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(9338..10042)
                     /locus_tag="ACG8ZV_002019"
     CDS             complement(9338..10042)
                     /locus_tag="ACG8ZV_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFS4997313.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            10173..10676
                     /locus_tag="ACG8ZV_002020"
     CDS             10173..10676
                     /locus_tag="ACG8ZV_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HFS4997314.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            10636..10974
                     /locus_tag="ACG8ZV_002021"
     CDS             10636..10974
                     /locus_tag="ACG8ZV_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HFS4997315.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            10995..12413
                     /gene="ffh"
                     /locus_tag="ACG8ZV_002022"
     CDS             10995..12413
                     /gene="ffh"
                     /locus_tag="ACG8ZV_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HFS4997316.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            12525..13103
                     /locus_tag="ACG8ZV_002023"
     CDS             12525..13103
                     /locus_tag="ACG8ZV_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HFS4997317.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            13107..13628
                     /locus_tag="ACG8ZV_002024"
     CDS             13107..13628
                     /locus_tag="ACG8ZV_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HFS4997318.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(13707..14261)
                     /locus_tag="ACG8ZV_002025"
     CDS             complement(13707..14261)
                     /locus_tag="ACG8ZV_002025"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HFS4997319.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            14514..14789
                     /gene="rpsP"
                     /locus_tag="ACG8ZV_002026"
     CDS             14514..14789
                     /gene="rpsP"
                     /locus_tag="ACG8ZV_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HFS4997320.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            14801..15052
                     /locus_tag="ACG8ZV_002027"
     CDS             14801..15052
                     /locus_tag="ACG8ZV_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HFS4997321.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            15177..15968
                     /locus_tag="ACG8ZV_002028"
     CDS             15177..15968
                     /locus_tag="ACG8ZV_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997322.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            16138..16659
                     /gene="rimM"
                     /locus_tag="ACG8ZV_002029"
     CDS             16138..16659
                     /gene="rimM"
                     /locus_tag="ACG8ZV_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HFS4997323.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            16649..17410
                     /gene="trmD"
                     /locus_tag="ACG8ZV_002030"
     CDS             16649..17410
                     /gene="trmD"
                     /locus_tag="ACG8ZV_002030"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HFS4997324.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            17546..17893
                     /gene="rplS"
                     /locus_tag="ACG8ZV_002031"
     CDS             17546..17893
                     /gene="rplS"
                     /locus_tag="ACG8ZV_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HFS4997325.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            complement(17929..18114)
                     /locus_tag="ACG8ZV_002032"
     CDS             complement(17929..18114)
                     /locus_tag="ACG8ZV_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997326.1"
                     /translation="MLEYSGFFIKAVTLKKDIIIVLFFLLLLIGRFILIHYSPLPIIK
                     EKTGSGCSNYMLRKKNP"
     gene            18151..18444
                     /locus_tag="ACG8ZV_002033"
     CDS             18151..18444
                     /locus_tag="ACG8ZV_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HFS4997327.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            complement(18532..18678)
                     /locus_tag="ACG8ZV_002034"
                     /pseudo
     CDS             complement(18532..18678)
                     /locus_tag="ACG8ZV_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332517.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamate
                     endopeptidase"
BASE COUNT         6399 a         3373 c         3832 g         5587 t
ORIGIN      
        1 ttattgcttt tgcaaaattt atttacctgt tttctggatc aacgatagtg tacattatgc
       61 tatccttgtt tggattttag gacgtttaaa gaggcacttt tttacataac ttaatccata
      121 gaccttttaa gcatgctgtg agataataat aaagaagagt ttaaagcgca ccccaaacca
      181 cttccccata agtgtattac gctttaaact cttttatatt tgaattcact aagaagcata
      241 ccatatattt gaatttacta agaagcatac catatttttg aaaaaaagtg agaaaaaagg
      301 cttataatta ggatttagag taattaatta gatgtttatt ttataggact gatactatag
      361 attacaaata gtatcgtatt tcgcaatctt aaaattatct tcttactgtg aataagataa
      421 taaaatttgt atttgtcctt tttaggtaac ttattttaat ctatatacct ttctggatca
      481 acgaaagtat actttatata gtcataacgc cgatggtaac tatgcactgt aacgataatg
      541 ctgctaaaat atctttttac gaaaaacatc acaaggaaaa acttaactat ggtattatct
      601 aaacataatt ttttcggtat ttaatattta attaggaggt aatattttgc ttttttatag
      661 taattttatc ttaatagtag cgatattatt acttctgaat atatggattt ttgataggag
      721 tagaaattca agtataggtt ttagaactaa acgaagtttg tcttctaaaa aaaattgggt
      781 atactcacaa actatttttt atggaggaat tgttttaatt agtttacttt cttcaacact
      841 ttattctttg aatattatag atgtttccac ctcaaattca atatctatta ttggaatcat
      901 tattgctgca attattacac aactgttttt agtgtttgga gagaagaaaa gaagtaaaaa
      961 atagaaaaac tagtgatagt tttggtgata taagaaaaac atatatgtat aaaaagaaga
     1021 aagtagcttc tctttgtaca tatatggttt gtttttatgg atgccgagct tttttataag
     1081 ataaggctac cgcccataac gacccaagga tttgtggaac taagtaaata cctgcaagaa
     1141 gcaagatcag ctgggtcggt tttaaaggat gatagaagta acgccattca gtaaaattgg
     1201 cgcaaaataa ataggaagtg acagtagata taatattggc aatgaataaa gatataatac
     1261 gcctgttcct ttgaaaataa tatccagcaa aaagagataa aaatatcaat gtgatgaacc
     1321 cgcttacgga atgataacga aaatcaagca gtaaggcgaa atgcacataa ggaacaaaag
     1381 ataaaagcaa cggaaggttt ttccagcaag tttttatcat ctttcatcac cacctaacaa
     1441 gtgttattat tttgttagtt ttattgtaaa ttgaatcctg caataatcaa ttactttttc
     1501 attatttcta gattaaatga ataaactctc atgccattat ctctaaaaaa aaagtttttc
     1561 cccctaattt ttttagatag aaaattgtat agtatgatga gagaaaaagt agtttggggg
     1621 aacgttaatg agaagaaaag cagtaatcga tcggctttat ttattttttt ggttttttcc
     1681 tatcgttttg ctacctttta catgggtaaa tgctgttgta caaggtgcgg agatattagg
     1741 cctgatccaa ggaagcggat ttgtggtttc taggaatttt ccagctttga ttgttttcta
     1801 tttagtgata agtgtaggtc tcttattacc aaaatctctg atcaatcact acaattggca
     1861 gctgctttac ttttcttgct tattagtatt tacatctatg ttttctttgc tgcctcgctt
     1921 gattatcggc cctaatggtt tgagcgagag tggattgaag gatttagctt attcctccat
     1981 gtatttcttg acgatcaaac catggttcta tttagtaatt gcctcattta ttcttgcaac
     2041 atttttttac ttctggacag aaatcaggat aaaaagtgaa cgatctgtat ctataaaaaa
     2101 taactattga tggtggatca tcagtaaaaa aacatatgag ctgcgtaaaa tgcatgtttc
     2161 tcatatgctt tttttattat tatgtaaaga atgcgaaaaa cgtttacatg atttttacat
     2221 aacttaacta tatttttaca gcaaccatac gagggattta cagtcgactg ataaacttta
     2281 gttgtaaata agaaaggagc aataaaatga aaaaagtatt gtttactcta ggtatgatgg
     2341 gaattctttt agccggatgc ggctcaggat caggaaatac agatggctct gccacacaaa
     2401 ataattcaag tgactcaaat gaacaagtaa aaatcgttgc ggtaggttcg acagcattac
     2461 agccgttagt cgatgcagca caagaaagct ttgtacaaga aaatccaaat tatcaaatct
     2521 ctgtacaagg aggaggaagc ggaactggtt tgagccaagt cgaagctgga gcagttacta
     2581 tcggaaactc tgatgtattt gcagaagaaa gagacggagt tgatgcttca aaattagtgg
     2641 atcataaagt agcagtggtc gggatggcac caatcgtcaa taaagataca gatgtcaaag
     2701 atatcaccaa acaggaattg attgatatct ttacaggaaa aatcactaac tggaaggaag
     2761 ttggcgggaa agatcaaaaa atcaacgtcg tgaaccgtgc aaacggcagc ggtacccgcg
     2821 cgacattcga aaaatgggga ctggatggtg ctacccctgt gcagtcccaa gaacaagatt
     2881 catcaggaac agttcggcag ctggtaagtc aaacaccagg agcaatcagc tatttagctt
     2941 tctcatatct cgatgattcc acacaagcac taagtatcga cggtgtagaa ccaaaagaag
     3001 agaatgtagc agataacagc tggggaatct ggtcatatga acatatgtac acgaacggaa
     3061 aaccttcccc tgaagtccaa aaattcttag actacatgat gacagaagaa atccaagaag
     3121 gacctgtcaa agaattgggc tatttaccaa tcacaatgat ggaagtagaa cgtgatcacg
     3181 aaggaaatat caaataacta gcagataaac atgccacggt agtcgttact attaaggaaa
     3241 aatcaactat gtttccccac atatacattt ttcctttaat tgtgaaaaat agttcctcat
     3301 attttgccgt tttttgagct aataccgagg gtcagctgat tgaacaccgt ttattcgaaa
     3361 aaaagagcta cgacatagaa ctgtcgtaac tttttttggc tcttcgtcaa atcgtgttgg
     3421 tgaagacaaa tttgaataaa acttagtccg atatgcggcg cgttctgtgc gccgcatatt
     3481 tttttagttt tcaaagatca gaccttgttg taaatagatc cgtgcccgaa agttataaaa
     3541 gttgcgataa ccaaacgcaa ttcgtttaat cagcttgatc ttgttattca gcccctcagt
     3601 gacgccgttt gagtgggaca ccttaaaggc atttgaaata cccgattggt agcaatggaa
     3661 gatcgtgaat ttctttttaa acgactgagg taacgtagat gaaattgttt taagggtttc
     3721 ttgaaagcct tccgtacctc gtttaacgaa ataatagcgt aataattgac aaaaatgata
     3781 cgcagttcgc aattcttcgt tgtagcttaa cagctcatca acgatttctg tttgactaat
     3841 tggtcgttta aacagtcgat gataatgccg tttgagtggc tcccatgtcg tggaatcttt
     3901 gagtaagagt ttccaatatc gcttgagccg acggtacttc ttctgatttt cagagtgtga
     3961 ggttcgaaaa cgattcatga tctggacacg taattgattg aagctgcgat tgatgtgttg
     4021 gacaatatga aagcggtcag ttacgatctc cgcatttgga aagactgttt taagcaactg
     4081 acaatagctg gcattcatgt ccatcactag gtacttgacc tttaaacggg cctttctagg
     4141 aaagcgcagg aagtattgag ttagtttgta aagtctgcga tcttcaagga tcgtaaatag
     4201 ctgattggtt gtcccatcaa cacaaataaa actcatggaa ccagaaacag aattcattga
     4261 tttgaactca tccatacaca acaccgtcgg aaggaagttc atacgtggct ggtaatgctt
     4321 cgttgcttca cgcaagatcc gtgtcaccgt cccatccgag acgaagtact tcttagcgat
     4381 tagtttacgt gattgatttt cgtacagttc catgagaatc gcctgcttca gttcctttgt
     4441 tagttgatga tgttcatcaa ctaagtccgt tttcgcagaa aaggtccttc cacaatcatg
     4501 gcagagaaaa cgggtacgtt ttaattctaa aatagttaac ttttctttga ctttcaacat
     4561 ctgagtgcgt gtcgtatagg aaccgttgcg gataatacga accgatcgac agtgttcaca
     4621 ataggaagaa gagtcatcca attttccttt aataaactgc gcttgaacgc ctttatattc
     4681 tttttcaatc agccattctt catcaaaaaa taaatgttta tctgttaatc cgagtaattt
     4741 tctagtatga ttatccattg agagactcct ttggtaggat gacgttttgg tcgactaaat
     4801 tttaccaaaa gtgagtctct ttttgagttg aaacgaagaa aaagtgttag tagaaaatcg
     4861 ccttcgattt tccaccaaca caaaatatta tagaaccctt tttttttgct atatgacagg
     4921 aatgaaaggt gtttgcaagc ttaatgtgag gaacactttc catatctgtt ctatactgga
     4981 taggagaagt ttggaaatat ccagaaaacg aaatcaatcg aggtagccac atgaagaata
     5041 aatggataaa tcgaagtaaa aaaaagaaag taacacaaag atcatcagat aaagtcatcc
     5101 gtctttttcc atcgtataaa gaaggattaa cggcagatca agtcaaggaa cgaatagaaa
     5161 aaggtgcagc aaataattca gtcgatccca cattcaaaac aaatcagcaa atcgtattgg
     5221 aaaacatatt tacgtatttc aatttgatct ttcttatctt agccattttg ctttgtttag
     5281 tagaatccta taagaacttg acttttttac cagttatcat agccaataca ggaatcgcca
     5341 tttttcagga aattcgatcc aaaaagatct tggacgaact aaatgtttta aatacagcaa
     5401 aagtcaatgt catacgagac gggatagaac aaacaataga tatagaagac cttgtaatag
     5461 atgacattgt tattttagag actggatatc aaattccagc agatgcagag gtcgtggaag
     5521 ggaaactgca agttaatgag gctttattga caggcgaagc agatgaaata accaaagaaa
     5581 taggtgatcc attaatgtcc ggcagtttca ttgtttccgg aaaagcttac gcccgattag
     5641 acaaagttgg agcagattcg tatatttccc agctgacagt caaagccaag acaatgggag
     5701 aaggagaaca gtcggagatg attgcttctc ttaatcaatt gatcaaatgg attgggatca
     5761 tcattattcc tatcggtatc ctgctttttt ctcaaagtta cttttttaat ggaaacacga
     5821 tcaaagaaag tgtcgttgca atggaagcag cattgatcgg tatgatacct gaaggactgt
     5881 acttgctgac gacgattgca ttagcattaa gtgcgactaa actagcaaag caaagagttc
     5941 ttttacacaa tatgaaaagc attgagacat tggcaagggt aaatgtcctt tgtgtagata
     6001 aaacaggaac gatcacagaa aataaaatgt ctgttcaaaa aatgatcgtc tctaaaaaac
     6061 aagaaataat cagtcagtca gatcaattgg aagcatgcat tgctgactat gcaaaagcga
     6121 tggcaggaga caatgcaaca atggaagctg ttaaagcata ttttacaaaa accactgatc
     6181 aatcctatca ccatgttatt cctttttctt ctgtccaaaa attcagcagt gtagcgttgg
     6241 cagacaaggt gtatgtttta ggagcgcccg aaatggtttt gcgcgatcaa ttgccggaat
     6301 atgcggaaga gtttgtttct ttcgctgaaa aaggctatcg cgtgttggtc tttggtgtgt
     6361 acgatgggat tcttgaagaa ccagtattga cagaagcagt cacaccatta ggctatattc
     6421 tgattgctaa tcctatcaga aaagaagcaa gagccacatt tgattacttc aaaaaacagc
     6481 aagtagccat caaagtgatt tctggagata atccgctcac cgtatccaat gtagctgtcc
     6541 aagcagggat ttcacatgct gatcagtacg ttgatgcatc taaattatca gaagaagaat
     6601 atgaagcagc tgtcgaaaaa tatacagttt ttggacgcgt caagccagaa caaaagaaaa
     6661 tcttcgttca attgataaag cgtaacaata cagtagctat gacaggtgat ggcgtgaatg
     6721 atattctagc catgaaagaa gcagactgca gtatagcgat ggcttccgga aatgaagccg
     6781 ccatgcaggc ctcacaagtg gtcttacttg attctgactt ttcacgcatg ccagaagttg
     6841 ttgcagaagg acggcgcgtt gtgaacaata ttgagcgatc agccagcttg tttttagtga
     6901 agaatatttt ctcctttttg ctctcactgt tttcagtgat ctttgctctg acctatcctt
     6961 tagaaccatc acaaatcaca ttgattagtt tgtttactat cggacttcca tctttcttgc
     7021 ttgctctaga agaaaacaaa aagcgaatca gagggaaatt catcatgaat gtgatggaaa
     7081 aagctgtgcc aggtggacta acagatatga tcgtagtcgg tgcgttggtg atctgcgggg
     7141 tgactttgaa tctaaataaa acagatgttt ctacagcatc taccatgctt ttgattgcag
     7201 tagggttcct cgttctctat aaaatctgtt caccgctgaa taaattcaga agtcagatca
     7261 ttcttttctg tgctagcggt aacttttttt cggtcatctt tttgcataag ctgttttcaa
     7321 tcaccggtat ctcagctgta tcacttttgc tgttgagcat tctatttttc tcggcagatt
     7381 cgatttttag gcatttgacc acattggtag aatatttgtt tgaacgtaaa aatgaaaaag
     7441 agcaaaagcc gtttagtcgc gtagctaaaa aatttctatc gatatttaaa cgagaaaatt
     7501 gacgaaaagt atctcaaaaa agagtaaaaa agaacaacca ctcgtgtatc tttcgaagca
     7561 ggatgagtca tccaacttta aaacgcacga gcagttgctc ttttttacat tttcggaatg
     7621 gtaacggtga aagtcgaacc tgttccaaga tgactgtcta cagtaatcgt accattaagg
     7681 agttgcacgt agtcttttac aatcgctaac cctaatccgg tcccgcctga atgtcggctt
     7741 cgcgccttgt ctacgcggta aaaacgctca aagatccgtt cctgatcctc aatgtcgata
     7801 cctataccaa agtcttggac agaaaacgat agatcatctg ttgcctgata gcggataata
     7861 atctcgctgt cgctttttga atattggaca gcattttcaa tcagattttt gataattgga
     7921 taaaggatat ctgttttagt agtaaatggt tcgttctttc caatcaatcg aatcgtcaac
     7981 cgtttctttt cgatgattgg ctgataattt tgaacgattt gctggaaata aggttctgta
     8041 taaattgtct ggatctcgta agaattctcg ccatcttttg acagctggat gatttcccga
     8101 atcagtttat ctaaccggat cgcatctttt tgcatgatct caagaaaaga agtcagagtt
     8161 tgcgggtcat cttttgcacc atccagtaaa gtctcggtaa aaccaatcag tgaagtcaca
     8221 ggagttttta attcgtgaga gacgttgcca acgaaatcct tttgtagctt ttctaaacgt
     8281 cgcactttcg ttaagtcata cgccacccct agaatctgtc cggtaccttc tgaattagta
     8341 aagtagcgca aactcaagtc taatgtctgc cgaccttctg taagggtgat ctcctgatgg
     8401 atcagcggat gctcaggagt cacttgatga atcagctgaa tgagttttgg ctcttgaatg
     8461 acttctgtgt accgctgttc aggttgatag cttaccacgt ttaaatgtag ctgcatcttt
     8521 ggattaagca gtagtaaacg agaatcagca tcatcaatca ggaatacgcc aatcatcagt
     8581 tcgttcagta acgtatataa ttgctcttct gtggtagtac acgcccgata catcttactc
     8641 atttgttcgc tcaacgcatt aatcgtctga tacaattctt cccattgatc gggtgtttgc
     8701 atgattactt ccgcctgatt aggattttgc accatttttt ttagtacggg cagcacggtt
     8761 ttcaatggct ggtttttttg atagatcaga taatagatca ttcctgcaag aacaaggaag
     8821 aaagacagaa agaagaaaaa gacccaacgg cgaaaactct cagttctcgg taaaaaaacg
     8881 cttgtcggtt ctgcgatacg taaaatggct tctaactggc cacttttttt gactggtaat
     8941 gcgacatata aaagatcctc attcaaagta gtacttttgc gcaaagcgct acctaggttc
     9001 ccaccattca atacggcttt gatttcggga cgggagtttc gctgttcatt caatgtttca
     9061 ttgtttgtgt caaataagat ctttccagta gcatccatta aagtaatccg ttcgttcgac
     9121 tgatggacga attcttccaa agcagttttg ttttgcgctg cttggaggtt ttcgacatct
     9181 aattgccgga tcagcagttg tgcttttttt gtcaggtagc tttcttgctg ttccacgatc
     9241 tgctgttgaa aataatggga aatcaattgc cagccaccaa aaaacaaact aactaaaaga
     9301 ataagaaaga agagacgttc ataaattttt ttccatttca tcgtttgggt tcctgaaact
     9361 tatagccaaa tcctctaata gtcaccaagt actttgggtg ttttggatct cgctcgattt
     9421 tttctcgcaa atgactaacg tgtacatcta cgattcggct ttgtcctgcg aagtcaaaat
     9481 tccaaatgcg gtctagcaat gtgtctcggt cgatcacacg gtcttttcgt ttcatgaaat
     9541 aaacaagtaa ttcaaattct ttcggtgtta gttcaatcag atggtcgtct acggtcactt
     9601 gataattggt caaatcagca gtgatttgtc caatcgatag atattcaggc tcagcttcat
     9661 cttttgattg cttacgaggt tcaattcgtc tgaatattgc tttcatacgg gctaatactt
     9721 cgcgaggact aaatggtttg gtcaaatagt cgtcagcacc tatttctagg ccaatgatcc
     9781 gatccacttg gtcatcttta gccgtcagca tcaaaatcgg tgtttcattt ttttcttgac
     9841 gcagccgctg agtgatctcc atgccatcca tcgttggaag catcacatct aaaatgatga
     9901 aatcaaatga ttgttctaat gctaattcta atccttcgcc tccatctgtg gcactggtta
     9961 ccttgtagcc ttctttttcc aaattgaacg tcaagagcgt tacaatagaa ggttcatcat
    10021 caacaactag tatttttttc attcaaatct cctttaaata ggtttcattc tgtttatatt
    10081 ttagcataga atcagtacaa agggctattt tacaaaagaa ataaatggta taataggaag
    10141 gcactttgct gaatagaaag gaagagcagt caatgattgg aatcagtgca tgtttaggcg
    10201 gtctggcctg tcgctatgat ggacagaaaa aagaagtacc agaattgatg gaactagttg
    10261 aaactggaga agctgtcatg gtctgtccag aagtgatcgg cggattacca attcctagag
    10321 atcccgctga aatcattggt ggaaatggat tcgatgtgtg gaaagatcaa gcaaaagtat
    10381 ggacgacaag cggcgaagat gtaacggaag cgtacaaaaa tggcgcgatc aaagcctatc
    10441 aaaaattgca ggaaaaacac attgatctag tcatcatgaa ggaaaaaagc ccttcatgcg
    10501 gaacccattc gatttatgac ggaagttttt ccggaataaa aaaaaatggt gccggagtgg
    10561 ctactgctta ttttattcag caaaaaatga ctgtgctctc tgatgaagaa tggctgaaaa
    10621 ctagaggtga gcagaatgga aatcgaaaag accaatcgaa tgaacgcgct ctttgaattt
    10681 tattcgacct tattgacaga aaaacaaatg aactacatgg aattatatta tgcagatgat
    10741 ttttcattag gtgagatcgc ggaagaatac gaagtaagcc gacaagcagt atatgacaat
    10801 atcaagcgga caagcaagat cttggaggat tatgaaaaaa aactccatct tttttctaat
    10861 tatattgttc gagaacaggt attggaaaat atgactgcat atattacaga taagtacccg
    10921 gaagataaaa aactacttga atatgtacag caaattcaag caatcgaaga ataaataaaa
    10981 ggaatgaaga aaatatggca tttgaaagct taactgaacg tctccagcag gcgatgggaa
    11041 aaataagaaa aaaaggaaaa gtatcagaag ctgacgtaaa agaaatgatg cgggaaatcc
    11101 gccttgcctt actagaagcc gatgttaact tgcaagtagt caaagatttt actaagcgcg
    11161 tacgcgaacg tgcggtaggg gcagaagtgc tggaaagttt atcacctgca caacaaatcg
    11221 taaaaatcgt tgatgaagaa ttgacgatca cacttggttc tgaaacagca gagttaaata
    11281 aatcaccaaa aataccaact gttatcatga tggctggtct tcaaggggca ggtaaaacga
    11341 cctttactgg taaattagcc aattatttaa agaaaaatga aaatgctcgt ccgctcctaa
    11401 tcgcagggga cgtatatcga ccagctgcga tcgaccaatt gaaagtatta ggtcaacagc
    11461 tagacgttcc tgtatttgat atgggaactg aagtcagccc ggtagagatc gtccgtcaag
    11521 ggatggagtt agcaaaagaa aagaaaaacg actatgtatt gatcgatacg gcaggacgtc
    11581 tgcatatcga tgaaacattg atggatgagt tgaaacaaat caaagaattg acgcaaccaa
    11641 atgagatttt gcttgttgtc gatgccatga ctggtcaaga tgccgtcaac gtagctgata
    11701 gcttcaacca gcaattaggt attacagggg tcgtcatcac taaacttgat ggggatactc
    11761 gaggcggggc agcactatcg atccgctcag tgacaggcgc accaatcaaa ttcatcggtt
    11821 ctggtgaaaa attgactgac ttagaagtat tccacccaga tcgtatggct agccgtatcc
    11881 ttggtatggg ggatatgctg acattgattg aaaaagcgca gcaagactac gacgagaaaa
    11941 aagcggaaga acttgcacag aaaatgcggg aaaattcatt cgatttcaat gactttattg
    12001 aacagcttga tcaagtgatg ggtatgggcc cactggaaga tctaatcaaa atgatcccag
    12061 gaatgaatca agtccctgga atcgaaaacg tcaaggtaga tccaaaagat gttgaacgca
    12121 aaaaagcgat ggtttattct atgacgccag cagaaagagc aaatcctgat ctgttgaacc
    12181 caagccgtcg tcgccgaatt gctgccggtt ctggaaacag tgttgttgaa gtgaatcgaa
    12241 tgatcaaaca attcaaggaa tcaagaaaaa tgatgcagca aatgtccaaa ggggatatga
    12301 acatcccagg tatggaccaa atgtttggtt caggcgtcaa aggaaaacta ggcaaaatgg
    12361 cgatgaatcg aatgatcaag aaaaataaga agaaaaagaa aaaacggaaa taagatgaaa
    12421 aaaacagctt cggtacagac tgaaaatgtc tactgccgga gcttttctat cagcaatttt
    12481 tattctttac taatacaatt actctaaacg aagaggtggc acagatgaga tgtccgtgga
    12541 gtgaacaaac agaaagtatg cggcaatatc atgatactgt ctggggtgtt cctgaatatg
    12601 atgaccaaaa gctgttccga aaattgatgc ttgatattaa tcaagccgga ttgagctggc
    12661 agacgatttt aaataaaagt gaagcattcg atgaagcata tgatcgattc gatatcaaaa
    12721 aagtcgcaaa ttatggagaa acaaaaatca gtgaactaat ggaaaacaaa ggaattattc
    12781 gtaaccgaag aaaaatcgaa gcagccgtcc aaaacgccaa agcagtcttg aaaattcaag
    12841 aagaaatcgg cagtttttca gagtatcttt ggtcgttttc taatggaaaa atcgttgatt
    12901 cttcttatca ttcacaagaa gaagtcccaa caacaagtcc tctttcagat gaattagcaa
    12961 aagatctaaa gaaaagagga tttaaattta tcggaagcac aacaatctat gcttttttag
    13021 aagctgtcgg gatcatcaat gatcaccttg acagttgttt ccgcaaagaa gaggtcgtac
    13081 gtatcggcag aaagggcgaa taaagcatgc gaaaaatcat attttatggt gctataagtt
    13141 tagatggcta tttggcaacg aaaacggatg atcttcaatg gctttttgac actccaacag
    13201 gtaagcaaac tacttatgaa gctttttatg aaacaatcga tacgaccatc atgggcagaa
    13261 aaacttatca ggaagcaaaa aaatatttgg agaccgaagc aatttatcca gagaaaaaga
    13321 atttcgtttt ttccacccac gcacaattac aattgccaga tgctgaggtc gtaaacgaag
    13381 atcctgttgc ttttctaaaa aatctacaaa tgacagaagg aaaagatatc tgggttgtgg
    13441 gtggcggtcg attgatcaaa ccgctattgg aacatcaaat gattgatgaa tggtatatcc
    13501 agattacccc tgtattatta ggggacggga ttcctttatt ccaaaaagga acatatgaag
    13561 cgcgttttga aatgctagac acgacacgat tcggtgaatt tatcgaattg cattatgtac
    13621 gaaagtagaa gtaaataaaa taaaaaaggc aactatatgc agaaatgtcc tgtacatagt
    13681 tgcctttttt attaccgtta tgctttttac tctgttaatt tgttagaaaa atctagatac
    13741 gcatctaaaa tcgtttggaa gaaacttaat gttccttcaa cgatattacc attttcatca
    13801 attagattcg caacgtttcc gatatatgct tccggttgct gcaaggttgg cacattcaaa
    13861 aagacaagtg attggcgtag atggtggttt gcgccaaagc cgccgatccc acctggtgat
    13921 gcagtaacga ctaaacctgg tttatgatcc caaacactgt gtccataagg tcttgagcct
    13981 acatctaaag catttttcaa tactgctggc acagaacggt tgtattcagg agtaacgaaa
    14041 acgacaccgt ctagtcccct cacttcctca cgaaaacgag tccattcagc aggagcctgt
    14101 tctggagttt cgagatcctc attgtaaaat ggcagatcat cgatttttac aaatacactt
    14161 tcgtaccctt caggaagcaa tttcgcaaaa gcttctgcta cttttttgtt gtaagaatct
    14221 tttcttaaac taccaataaa aaatccaatt ttttttgtca tacgattttt cctccttcaa
    14281 actatctata ataatcttac aaaagataag taactggagc aaataaaaac acttactgac
    14341 aaaagctaca tagaagatag attacttatt tttaacaaaa aagaagtcta aaatcttcta
    14401 ttttctaaaa aaaatcgaat ttaatcaagc tgtaaagaaa aaaagcttta cagggtaaaa
    14461 aaaaactgtt acactacatc ttgtgaataa aacaatggag gtggaaataa ataatggcag
    14521 ttaaaatccg tttaaaacgt atgggttcta aaaagagtcc gttttaccgt atcgtcgtag
    14581 ctgattcacg ttctcctcgt gatggacgtt tcatcgaaac tgtaggtact tacaatcctt
    14641 tgaaagaccc tgcagaagta gttttaaaag aagacttagt tcttgactgg ttatcaaaag
    14701 gtgcacaacc ttctgacact gtacgtaaca tcctttcaaa agaaggcgtt atgcaaaaac
    14761 accacgaagc taaattctca aagaaataag gtgaccggat atgaaagatt taagcgactt
    14821 agtcttaaca atcgttcgtc cgctagtcac ttatcctgat caagtcaagt tagacgtcgt
    14881 agagtcgaaa gacttttacg agtacaatct aacagtggct cctgaagata ttggccgtat
    14941 cattggaaaa caagggcgtg ttgctaaagc aatccgcaca atcgtttacg gtgttcggat
    15001 caatgcaccg aaaaaagtgc gtttgaatat catcgatgat aaggaaaagt aaataaacgt
    15061 gctgtactcg aattttcgag tgcagctttt ttgttttttt tattaattga agaaatgatt
    15121 atttggcaaa acaagcaaga aagcgtatcc ttataggagg agggagtgaa cagccaatga
    15181 gaaagaaaat gttatttatt ccatttgctc tattgttaag cgcttgtagt tcggttactc
    15241 aagaatcaga caatacacat ctatcaagca gtatatctga aactgttacc agtccagaaa
    15301 aaagtagtac caaaacggct tccaccactg aacaaacaat ggctacctca aataatgaga
    15361 aaaagactgc tttagaccag ttgaaagaac aacagccaaa tgttcccatg cctctagatg
    15421 taccagtctc ttcaggctat ctcaatatcg cagcgacaca tacaaagcaa ggttattcta
    15481 ttttatatta cagaacagat cgtcccctcg ggttgaatgc tgacgaattg aatcaagaaa
    15541 cgcctattgc aacctatcta tatcaatatg ggtttgcttc tagtcaagaa acaatccaag
    15601 ttttgcagcc atttgagatc gacacaaatg gtcagcaagt ggacttaggt tctcgaatca
    15661 cagggtatca gcaaggtgca gcaggttcaa gttttcttga atggcaagaa ggaaactggc
    15721 gtattcgaat ccgtgggaat aatatagaag gccaagatcc cttactatta gctaaagaaa
    15781 tcgtagctta tttggaagaa aacagtctac cagcacctga acaatttggt aaaattactg
    15841 ttgatatggg tgatacgacg aatcgagccg tagaagtaag ctggcaagaa ccgaaaaatg
    15901 cctatacgat cactcatcaa gatcctatgt ctgcgttgaa gatggcagtt tctatgaaga
    15961 ggttgtgaaa tcagcgcgct gatctgagcc catcatttaa ctccaagtca caggaagtaa
    16021 tcaaaaatag cacgccgcat ttttgcataa ttttggctta ataccttaaa agaaaactag
    16081 aattgcctct tcacacatgc taaaataaaa cagacaaaaa agaaatgggg atataagttg
    16141 actgaatact tgaatgtagg aaaaatcgta aacacacaag gtatcaaagg cgaagtccgt
    16201 gttatctcaa caacggattt cccagaagaa cgttacaaaa aaggaacggt gctaacacta
    16261 ttccaagacg gaaaagcacc tgtggaatta acagtcaaaa gtcatcgcaa acataaaaat
    16321 tttgacttat tgagttttga aggacatcct tctatcaatg atgtggaaaa atatcgggat
    16381 ggcatattaa aagtgtcaaa agacaactct gtagatctag ctgaaaatga attctattac
    16441 catgagatca tcggtctgca tgtattagaa gatggaactg agttaggtaa agtaaaagaa
    16501 atcttgtcac caggtgccaa tgatgtttgg gtcgttcaac gtccgaaaaa agctgatata
    16561 ttgcttccat atatcgcttc tgtcgtcaaa gaagtcgatt tagaagctgg agtggtccgt
    16621 gtagaaattc cagaaggact gattgacgat gaagattgat gtattgactt tatttccaag
    16681 aatgtttgaa ggtcctatgg gggaatccat catcggtaag gctgtagata aaggattatt
    16741 agatatcaat atctctaact tccgcgatta ttcagataac aaacatcaga cagtagatga
    16801 ttatccatac ggcggtggag caggtatgct gctcaaagtc cagcccatct atgataacat
    16861 ccaagccatt gaaaaagctg caccggatgt caaaaaaaga gtaattcttc ttgacccagc
    16921 tggtaaacga ttcgatcaga aaatggcaga agaattttca caagaagaac acttagtatt
    16981 catttgtggt cattatgagg gatatgatga acgtatccgc acattagtga cagatgaagt
    17041 ttccttagga gattatgtcc ttactggggg agaattaggt gcgatggtca tgatcgatgc
    17101 aacagttcgg cttttgccag atgtgttagg gaatcagact tcagctcaaa cggattctta
    17161 ttcaaccggt ttattggaac atccccaata tactcgcccg gcagaatata aagggatgaa
    17221 agtaccagaa gtattgacaa atggaaatca taaattgatt gaagaatggc aattaaaaga
    17281 atcactaaga aggacctatc aacgtcggcc tgatcttttg gaaacacttg aatggacacc
    17341 tcaaatgacg aaatttttag aagaaatcaa gaaagaagaa caagaaaaaa cagcagatga
    17401 agccaagtga ctttttctaa aatcttcttt acagtaggtt gataatatgt tagtatttta
    17461 tggtgagtgc aaaagcactt aactattacg atattccgct gtgagaaaag ctcataagaa
    17521 tatttggaat aaggagaaga aaaccatgaa tccattaatc gaagaattaa caaaagaaca
    17581 attacgttct gacatcccag cgttccgccc tggtgacact gtgcgtgttc acgcaaaagt
    17641 tgttgaaggt actcgtgaac gtatccagtt atttgaaggt gttgttatca aacgccgcgg
    17701 tgctggaatc agcgaaactt atacagtacg taaagtttct aacggagtgg gcgttgaacg
    17761 tacattccca ttgcatacac cacgtgttgc aaaaatcgaa gtagttcgct acggtaaagt
    17821 acgtcgtgca aaattgtact acctacgtgc attacacgga aaagctgctc gtatcaaaga
    17881 aatccgtcgt taatcattgt tatcagactg agaaagaacc cttggtattc aagggttctt
    17941 ttttcttagc atgtaatttg aacaccctga tccagttttt tctttaatta ttggtagggg
    18001 agaataatgg attagaataa atctacctat aagtagtagt aaaaaaaaga gcactatgat
    18061 aatatctttc ttaagagtaa ccgctttaat aaaaaatcca gaatattcta acataaatgg
    18121 agtattctta gaatcaaaag gagaaagaag atggtttata cttatacgga gcaagaaaag
    18181 atgaaagttt tagacacatt catgaatgat ggaaaagtaa aacaagtacc aagttcaaca
    18241 aaaaagaaat acatcctatt gaaagaagtc ttgaaacgct ttgaccatgg agtgacttat
    18301 acagaaacag aggttaattc gatactgctg aacgtatttt ctagtggcga ttatgtcgaa
    18361 caaagacgtt atctaatcac atttggcttt ttcaaaagaa gttcagacgg tcgggcatat
    18421 cagatgatgg gaattgaaaa ttagaagttt taatttatac tcattgaaaa aagttcaagt
    18481 atgcgatatt ggttctacac cgcatacttg aacttttttt gtcatctgta tctataatac
    18541 aaagccaaga acgttattca aaatatggat agctatgata aaagctaatg agcgattcgc
    18601 agttaaataa gcaatcgtca gtaaaatcgt tccaggagcg tacatgaaaa aatcaattgg
    18661 atgcgttaca tgaataaaga taattctctt ttatttgtac gaataaatac caaaacgtac
    18721 ctcctaaaat tagattttgg acagatgccc tttaaaaaga taacaagatt tcgttcttga
    18781 aacaatatat atgcttttat tccaatgagg ttgtgaaaac agtattttgt cctgagcgtt
    18841 agaaaattga aaatggggaa tagcaactcg tactttacca ttttttaagt gaatacaaga
    18901 tcagctaatt gaacaccgtt tattcgtgat gagggacaca acactgcagt cgacacattt
    18961 ctcttttatg ttcaaagata acaaatattt aaaacaaaga aaaatagtag ataatcccgt
    19021 cctaactctt ttattcttcc ctcatagctt ccaaatttaa gcaatacttc aattaatcaa
    19081 gttttatctt tttttttcaa taatcgtaaa aaaagagtat tttttattta aaaataaaat
    19141 ctttgtatta aaggacaaga ctaaaataac cttagaataa aaagagaaaa a
//
LOCUS       DAZULR010000045        19136 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.046, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000045 DAZULR010000000
VERSION     DAZULR010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19136
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.046"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..190
                     /locus_tag="ACG8ZV_002035"
     CDS             <1..190
                     /locus_tag="ACG8ZV_002035"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997328.1"
                     /translation="IGGFKMSHTLLIKDTLNILDLNINIHFEENCLTKEKYKGQICLI
                     YKGTLQYTPEEYPHLPIY"
     gene            250..483
                     /locus_tag="ACG8ZV_002036"
                     /pseudo
     CDS             250..483
                     /locus_tag="ACG8ZV_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(531..650)
                     /locus_tag="ACG8ZV_002037"
                     /pseudo
     CDS             complement(531..650)
                     /locus_tag="ACG8ZV_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360451.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
     gene            complement(1866..3032)
                     /locus_tag="ACG8ZV_002038"
     CDS             complement(1866..3032)
                     /locus_tag="ACG8ZV_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HFS4997329.1"
                     /translation="MKISVFGLGYVGLANSLLLAQKEQVKAYDIVEEKITMLQNGISP
                     IEDKEVHEFLKRDDLNVEFTSNFTDAVNFGDYLIIATPTDYDEKKNYFNTSTVEDVIE
                     KALAIRPDSTFIIKSTVPVGYANEIKAKFGTENIIFSPEFLREGKALYDNLYPSRIIV
                     GECSARGREIATMFQRNAFNKDASVLLTHSTEAEAIKLFSNTYLALRVAYFNELDTYA
                     EFRGLDSKQIIEGVGLDPRIGSHYNNPSFGYGGYCLPKDTKQLRANYEKVPSNIISAI
                     VDANTTRKDFIAGQILAKKPNVVGIYRLTMKAGSDNFRYSSIQGIMKRIKAKGIEVVV
                     YEPTLDEDEFYHSQVLKDINEFKNISDVIVSNRFEDILKDVEEKVYTRDIFGDN"
     gene            complement(3120..3548)
                     /locus_tag="ACG8ZV_002039"
     CDS             complement(3120..3548)
                     /locus_tag="ACG8ZV_002039"
                     /inference="COORDINATES: protein motif:HMM:NF012360.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HFS4997330.1"
                     /translation="MIFGKKHSLVEVPEFGSEPYLIEIGDNFRCSFGVKFITHDGGVW
                     VLRKMSSVSESTSKIGRIKLGNNIFIGIYSIVFPGVSIGDNVIIRANTLVNKDIPNNS
                     VVAGSSCKVISTIEEHYEKNKNEFIKYRTSMILKQKNFFY"
     gene            complement(3634..5058)
                     /locus_tag="ACG8ZV_002040"
     CDS             complement(3634..5058)
                     /locus_tag="ACG8ZV_002040"
                     /inference="COORDINATES: protein motif:HMM:NF026018.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HFS4997331.1"
                     /translation="MDSSSNKSHSIAKKAFIYAIGTLSSKMISVIIIPIYAVYISVAD
                     LGSFDYQNTIAQFLSPVIFGAIWEAILRMGLGKEKNIQKKVVTNSICFVIANTVILAI
                     FLPIIYRMIFPNLEYYQLFVFQLIFTPILSVFQYIVRALGESKIFVMSGIIAAGINLL
                     LLTIFVVTMGMGILGLLLSIIISNVINLIFLIFRGQIFQYFATSSFDFLFLKSMLKYS
                     IPLTLNLTFGWLIVGFSRFYIGTYIGVTENGIFSFAMKFSSIILTLTSIVSMSMIEDA
                     VITSENDDFIERFVEKNTYIFKMYIRLATLSIPIICCAYSFITNPDYKKSLVLVPILV
                     IMACFSGMTTNIGNIFAVYNKTNQLLMISVVSGLLSVVGTYLLGYSFGVIGVSFATLL
                     GTLVLFGLRYYFGRKIAYYAFDWKRISLLLVLYSAIAFVCIHRGFYFNLFLTIIFSAI
                     FVFTYKQLIITYLKKFFRIKMAKR"
     gene            complement(5426..6436)
                     /locus_tag="ACG8ZV_002041"
     CDS             complement(5426..6436)
                     /locus_tag="ACG8ZV_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase"
                     /protein_id="HFS4997332.1"
                     /translation="MKILITGGAGFIGFHLSRKLLKETENQIVAIDNLNDYYDVQLKE
                     DRLTILYDYNNFKFIRMDLLEKEKLDSLFESEGFDIVIHLAAQAGVRYSIENPYAYID
                     SNIIGFLNILEACRNFPVKHLLYASSSSVYGGNTKVPFSTEDSVDHPVSLYAATKKSN
                     ELMAHTYSHLYKIPTTGLRFFTVYGPFGRPDMAYFSFTKNILSGKEIKIFNHGKMERD
                     FTYIDDIVEGITRLINKVPEPNSDWTDIDDLSSESWAPYKIYNIGNNKPVALLEFVET
                     IEKYLGVKANKIFLDMQPGDVVRTYADIEDLEEKINFKPNITLDEGIKKFVEWYTVYY
                     LS"
     gene            complement(6688..7626)
                     /locus_tag="ACG8ZV_002042"
     CDS             complement(6688..7626)
                     /locus_tag="ACG8ZV_002042"
                     /inference="COORDINATES: protein motif:HMM:NF016640.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase domain-containing protein"
                     /protein_id="HFS4997333.1"
                     /translation="MGRQELYSLAINELEKRNLEIHELNQKNNSILGMKIRNKINQLN
                     QMKKRDNLLPAKYTLKSMTGKGPIKDYSNRENRSDELRKKELTNQGTPKRIAVYSCIT
                     GNYDSIKEPDFSHPLVDYYLYTDNVITSEHWNIREIPKYISELKNNILINRYIKFHPN
                     ELFTDYDFTLYVDGNVTITSDITGLLNSSSKLGLSMHKHSERKSLYSEADALIAVGKG
                     NKESIIEQISKYREEGFPDNFGLAEATVILVDLNNSIAENLLDLWWREYLNSESGRDQ
                     LAFPYVLWKSGHAMKEVTTLGNNVYKSAKLRIISHY"
     gene            complement(7663..8754)
                     /locus_tag="ACG8ZV_002043"
     CDS             complement(7663..8754)
                     /locus_tag="ACG8ZV_002043"
                     /inference="COORDINATES: protein motif:HMM:NF026247.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpsG family protein"
                     /protein_id="HFS4997334.1"
                     /translation="MDTEASLEINQEKSVSQKKWSTSNKILSGVLLLIMWIIMAFNTQ
                     NADYYAYSVLYNGIAQFGMDFSSDSIEPGFRAVMYVCTFISSQYQIFLLIISTVLLSA
                     LLYVIRLFTTNVFLVLFLFFIFGFTSQAIQVRMFSALIFILLAFYHLTKLRGSKAIFK
                     YIFFILVAGLFHNLAYFYLPFFIVKINKKITGYVTILSLLLFSIGQSYISSIFINTKY
                     DAYFDRNSTSISHVVMFALFFSANLFLVHKLSKMNIYEKKVISLSSYIFSINMLASTS
                     IVFLLISNNFIRIIQNIFVLNYIIYASVLMSNYKRTKVKNYIYLLAYFFFIIVCLIFI
                     NIRGTAFVNGILPLFRENIIFKAVYYFFE"
     gene            complement(8726..9622)
                     /locus_tag="ACG8ZV_002044"
     CDS             complement(8726..9622)
                     /locus_tag="ACG8ZV_002044"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF025017.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFS4997335.1"
                     /translation="MKNKIGIIIVTYNPDNNIKLLVDTLIQEKQNKLIIVDNGSDNIN
                     SFQFEMMENLILKKMNENIGLATAQNIGIEIAKKEKCDYILLLDQDTIIQKNLSLKLL
                     EEFTNIEAKDKDIGIIVPNYFENSNDESVSFTCKNERGRYVKKHFASTSGSMKIAFAN
                     SSGMFFKSELIDDVGNMKDEFFIDQIDVEFCKRVANNGYNIYVTNQVYFYHHVGDGEN
                     LKIGSKKIKIDNHNSTRKYFIARNSTLVKRMYKSDKEFSRLMNKRLLKFFIAIAFETD
                     KLSRFRAAIRGVRDGYRGVIGD"
     gene            complement(9612..10772)
                     /locus_tag="ACG8ZV_002045"
     CDS             complement(9612..10772)
                     /locus_tag="ACG8ZV_002045"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997336.1"
                     /translation="MSENKKKWLLIHPFDYISRTNILEEILTENSIEYFNVVSDYSHI
                     RKQFLSSKERHMIKNRHVIKTIGYKKNISVMRILSHIWFSIKTLLFIRKEKPEIIYCR
                     IPPNTLVFFIAKFSRCNRVIFDVYDLWPESMPGIGNKYKFFTDLWKKLRDQYLSNSSL
                     VITECDYFKKFIKISGESKNMTIYPCSFNVDDQNDYGEKIVNKSLESTLNLAYLGTIN
                     NIVDLEAINELLKTCKRKFGNKINLYFIGKGESKTKLADICEKNHIEFVDCGVIYDNA
                     EKKVILDKCHFGLNLFKSNTIIGLSLKSIEYFRFGLPIISNLSGDTKEIVKRYNVGIN
                     YNSTVDENEMLKFYQCNKNINENVRKIYATIFSEQVLKMKWNEVYKVMNDEK"
     gene            complement(10765..11394)
                     /locus_tag="ACG8ZV_002046"
     CDS             complement(10765..11394)
                     /locus_tag="ACG8ZV_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HFS4997337.1"
                     /translation="MSNRGIYEKFFKRLIDILFSILGLIMLWPLMTFVAILVRIKLGS
                     PVIFKQQRPGKHEKIFLMYKFRTMTDQRDEEGNLLSDDIRLTQFGKILRSTSLDELPE
                     LWNILKGDMSIIGPRPLLVEYLSLYSNEQRKRHFVRPGLTGLAQVSGRNAISWKEKFE
                     KDIEYVENISMMKDIKIFFLTLKKVIVRDGITSVASGTTEKFEGAKIDE"
     gene            complement(11387..12505)
                     /locus_tag="ACG8ZV_002047"
     CDS             complement(11387..12505)
                     /locus_tag="ACG8ZV_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HFS4997338.1"
                     /translation="MENKRILLASPHMSDEGYEQEYVKEAFDTNWVAPLGMNVNGFEE
                     ELAEYVGASHAAALSSGTAAIHLALKAAGVGKDDIVICQSLTFSATANPIIYQGAIPV
                     FVDSDYETWNMNPEHLRTALEKYPNAKAVLVVHLYGLSAELDEITKICKEHNVVLIED
                     AAESLGTTYKGKYTGTFGDYGIYSFNGNKIITTSGGGMLVSNDKEKVEKVRFWATQSR
                     EKARHYQHNEIGYNYRMSNIVAGIGRGQLKVLNERIEKKRYIHSFYKKELSKLSNIQF
                     MPENNWNEPNYWLSVITVKGINTNHLIDELDKNNIEARPIWKPMHLQPVFDKYEYIGT
                     DVAQTLFEKGICLPSDSKMTDDDLYRVTNTIKRVMQNV"
     gene            complement(12507..13139)
                     /locus_tag="ACG8ZV_002048"
     CDS             complement(12507..13139)
                     /locus_tag="ACG8ZV_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HFS4997339.1"
                     /translation="MKAIIVGAGGFGKEIAFLLESFSRYELIGFVDDSLKMQNQELVG
                     KTVLGTIDSLLELEEETAIFLGIASPDIKEKIYQKINKNNKLIFPNLVASSALVGINV
                     QLGIGNILMPYTTYTADVVLGNFNMINIGSTIGHDTQIGNYNSIFPSVNISGHVLLGD
                     KNEIGVGTKIIQNLRIGNMNIIGAGSVVIKNINNKTKNVGVPTKVIERWD"
     gene            complement(13150..14967)
                     /locus_tag="ACG8ZV_002049"
     CDS             complement(13150..14967)
                     /locus_tag="ACG8ZV_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HFS4997340.1"
                     /translation="MFVLTRRRKIATLVFVDSLLLIAANIAAAKFMKPFVAIPMDLIL
                     ISIGLSIGFYLFYGSLFKVFTRINRYTNLREIIAIFGSLSASAASSIIILLFINKQYS
                     LRLVIFAYLLSLLLIIGSRLIWRIYIETKNMRYLSTDSAKNTLIVGAGEGGRILYNSF
                     LGSKTAQDIHVIGFVDDDPNKRNTYLSGKKVLGSLKDIPELIEKYDIQMVTIAIPSLS
                     RKKLRRIFELVESAHVKVNTMPSMEELASGKISVSKLKTIDVVELLGRDEVELDIESI
                     KDQITNKVILVTGAGGSIGSEICRQIIQFDPAKLLLLGHGENSIYLIDRELRTHHQKC
                     PTEIVPIIADIQDRKKINEIMEQYHPDIVYHAAAHKHVPLMEYNPKEAVKNNIFGTKN
                     VAEAAKAAKVKNFVMVSTDKANNPPNVMGSTKRIAEMIVTGLNEEGCTKFSAVRFGNV
                     LGSRGSVIPVFREQIAQGGPVTVTDFRMTRYFMTIPEASRLVIQSGALAKGGEIFILD
                     MSEPVKIVDLAKNMIRLSGYSEDEIEIIETGIRPGEKLYEELLLDKERNDEAVYEKIF
                     VGNIKGYSMQTVMEFVKSLPQDDEQLAKDIVTFANASNK"
     gene            complement(14980..15744)
                     /locus_tag="ACG8ZV_002050"
     CDS             complement(14980..15744)
                     /locus_tag="ACG8ZV_002050"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsB/CapC family capsule biosynthesis tyrosine
                     phosphatase"
                     /protein_id="HFS4997341.1"
                     /translation="MIDLHCHILPGIDDGAENIDASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAEWLFFELLQLGKTPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKMMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVAQMKQVAKDLINGDEISYPVYEEVKKKKFGLF"
     gene            complement(15772..16470)
                     /locus_tag="ACG8ZV_002051"
     CDS             complement(15772..16470)
                     /locus_tag="ACG8ZV_002051"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004713 - protein tyrosine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0004715 - non-membrane spanning protein
                     tyrosine kinase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HFS4997342.1"
                     /translation="MARTQKQKATQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVIYKTFKLNNAS
                     GLSTVLSSSGSVADEIQRTPVDNLSILPSGPKPPNPSELLSSPRMDQILAEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLTKAKELLDMVQARVLGVVYN
                     GAEHSRDAGYYYGN"
     gene            complement(16482..17261)
                     /locus_tag="ACG8ZV_002052"
     CDS             complement(16482..17261)
                     /locus_tag="ACG8ZV_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzz/FepE/Etk N-terminal domain-containing
                     protein"
                     /protein_id="HFS4997343.1"
                     /translation="MEETISLKEIFETLRKHLVTIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQAISTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGSAPARPKATNDKTAPSRRSRSRV"
     gene            complement(17277..18221)
                     /locus_tag="ACG8ZV_002053"
     CDS             complement(17277..18221)
                     /locus_tag="ACG8ZV_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFS4997344.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTLQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            complement(18267..19046)
                     /locus_tag="ACG8ZV_002054"
     CDS             complement(18267..19046)
                     /locus_tag="ACG8ZV_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997345.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKNFLNPEITEETITSLSNKLSSVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVVIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSQIEQIRNEKISAAYATKAQTVAQQMGYSNISY"
BASE COUNT         5947 a         3674 c         2807 g         6708 t
ORIGIN      
        1 cataggagga ttcaagatgt ctcatactct gcttatcaaa gataccctaa atattctaga
       61 cctaaatatc aatatccatt tcgaggaaaa ttgtttaact aaagaaaaat acaaaggaca
      121 aatttgcttg atttacaaag ggactcttca gtacacacca gaagaatatc cacatcttcc
      181 aatatattaa aagaaccttc ttgaatcatt gagtgaaaga aaagagattc gtcactattt
      241 gaggactgtt taactagaga cattagcgat ctgcctgaaa cctatacaac cactttacga
      301 acgtttaaaa attttctgcc acagattcaa aatgcgctta actgcagcta ttcaaacaga
      361 ccattggaat gtttaaacaa ccacatcaaa gtattaaaac gcaatacgta tggctttcgc
      421 agcttttaca atttcaaact acggatcatg attcgtcatg gcaaaacatt tttaaccaaa
      481 taaacagaag aatgtgggat aaatctaaaa atcagttttg ctacagactc tcgagtaaac
      541 ggcgggagca gaagcaactc cttcggaaat aagccgaaat tcacaaaaat ttgaaaagca
      601 attttcgtga atttcttctt atttctcgga gttaaacact tctgtcccag cctcttctgt
      661 ccaaattatt ctaagatttc tctttaccaa catcatttga caaagagctt cttttttgaa
      721 tactatattc gttctgtttt tcatcttcaa atacgaactc atccgcagaa atatttgtca
      781 caactccatg aatcttcttt tcattaccac ctatatacca caggattcct acacagaaac
      841 aacaaaaaaa tagcataaaa taggttttct ttattttata tccctccttt tagattaaaa
      901 gctcacagaa aacgctttct aaaaagacaa tagaataatc ataatttttc attttgtatt
      961 atttatacaa ataatacgca tgttactgaa aaatgatatg gttccctact ttttgagata
     1021 agttaaataa aatctgtcat cgataaaaca gctagtacag taatgataaa tagtaagaac
     1081 ttaaaatatt ttggattttt atttttgaaa taatcgaaga aaagtaaaag tgataacgaa
     1141 atagcaaaca agattatatc tataagatta ttcattgaga aatcgcccca tatggaactc
     1201 tattttgacc tgacacaccg agacataaag caatcatatc ctctgcattg ttttatacta
     1261 ttagaactat agctacacct attggatgct actggctcta agattaatgc taatacagta
     1321 acatcaatac ctaaactagc agaaactcta tttgcatctt caatttcaga tgcctggact
     1381 gtcgtgacta gcgccgtagt agaaaaattt actggtacta acaaagatgc agacacgact
     1441 tttatttcac ttatccttta tcccataacc taaacttcaa tcattacttg tgagctgatc
     1501 aatgttcttc caagtctgaa agaacattga tcagcttggc aaacaaataa tgttttcaaa
     1561 tacttgatcg atgaaaaaaa gctattggta ataacagtaa ttgcattttc cattttcgtg
     1621 tcagatactt cgcttacagc tggtaaacga tcaatcccat tgtcaaattt tggatttttt
     1681 tctgatgatg tcttgcttta gttcataaaa taatccagca ataaattcct cgcaaggata
     1741 gccaacttca ttttcctaat cggaattttt aaacttatcg gtatagatac agatgcaatg
     1801 agaacaaaca tttatttcga gtcaccatct aaaatatttt cctccatgta cccgttcatt
     1861 attatttagt tatcaccaaa gatatctctg gtataaactt tttcttcaac atcctttaaa
     1921 atatcttcaa accgattaga tacgatcaca tcagaaatat ttttaaattc attaatatct
     1981 ttcaatactt gtgaatgata aaattcatct tcatccaatg taggctcgta aacaaccact
     2041 tcaattcctt tggctttaat ccgtttcata attccttgga tcgacgaata tcgaaaatta
     2101 tctgaaccgg ccttcatcgt taaacgatag attccaacaa catttggttt tttcgccaaa
     2161 atctgtccag caataaaatc tttccttgtt gtatttgcat caacaattgc actgatgata
     2221 ttgcttggta ctttttcata gttggctctt aattgttttg tgtctttggg taaacagtat
     2281 ccaccatagc caaaagaagg attattataa tgcgaaccga tccgtggatc caaaccgaca
     2341 ccttcaataa tttgcttact atcaagccca cgaaattctg catacgtatc taattcattg
     2401 aaatacgcca ctcgcaatgc caaatatgta ttcgagaata atttaatagc ttctgcttca
     2461 gttgagtgag tcaaaagaac tgatgcatct ttgttaaatg cgtttctttg aaacatagtt
     2521 gcaatctcgc gaccacgagc agaacattct ccaactataa ttcttgatgg atataagttg
     2581 tcgtacaaag cttttccttc acgcaaaaat tcaggtgaaa aaatgatgtt ttctgtacca
     2641 aatttcgctt taatttcatt tgcatagcca actggaactg tcgacttaat aatgaatgtt
     2701 gaatctggac gaattgctaa agccttctca attacatctt ctactgttga tgtattaaaa
     2761 tagtttttct tttcgtcata atctgttgga gttgcaataa tcaagtaatc accgaagttt
     2821 actgcatcag taaaatttga cgtaaattcg acatttaagt catcccgttt taaaaattca
     2881 tgaacttctt tatcttctat tggtgagatg ccattttgta acatcgtgat tttttcttcc
     2941 acgatatcat aagctttgac ctgctctttt tgtgctaata atagtgaatt tgctagacca
     3001 acatagccta atccgaaaac tgaaattttc atattcttcc atacgctcca atcaaatttc
     3061 attttatagt attttagctg ttatcctttt gaacatattc cttattcaat caatattatt
     3121 taatagaaaa aatttttttg cttcaaaatc atcgaggttc gatatttaat aaattcattt
     3181 ttatttttct cataatgctc ctctatagtt gaaatcactt tacatgaact acccgctaca
     3241 acactattat ttgggatatc tttatttact aaagtgttcg ctctaataat tacattatcg
     3301 ccaattgaaa ctcctgggaa aacaatagag taaataccaa taaaaatatt atttcccaat
     3361 ttgatcctac ctatttttga agttgactcg ctcacagaac tcatcttcct taagacccag
     3421 actccaccat cgtgtgttat aaatttaaca ccaaatgaac atctgaaatt atcccctatt
     3481 tcaattaaat atggctcgct cccaaattca ggaacctcta ctaaactatg tttttttccg
     3541 aatatcaaac cttcattaat acattctcgc agattttttc caaatagttt tctctttatt
     3601 cttcgaaaga ttctattctt acttcgtata ccctcacctt ttagccattt ttattctgaa
     3661 aaattttttt agatacgtta taattaattg tttatacgta aaaacgaaaa tagcactaaa
     3721 aataatcgtt aagaaaagat taaaatagaa gcctctatga atgcatacaa aagcgattgc
     3781 ggaatagaga actaaaagta gcgatattcg cttccaatca aatgcataat aagcaatttt
     3841 ccttccaaaa taatatctaa gtccaaataa tactaaagta ccgagcaaag tagcaaatga
     3901 gacaccaatt actccaaaag aatagcctaa taaataggtg ccaacaacac tcaatagacc
     3961 tgacactact gaaatcatta ataactgatt tgttttattg tatactgcaa atatatttcc
     4021 gatatttgtt gtcatcccac tgaaacatgc cataataact aatattggaa ctagaactaa
     4081 tgatttttta taatcagggt tggttataaa agagtatgca cagcaaatga taggaataga
     4141 aagagtcgct aacctaatgt acattttaaa aatataggta tttttctcaa cgaatctttc
     4201 gatgaaatca tcattctcag acgtgataac cgcatcctct atcatagaca tactaacaat
     4261 acttgtaaga gttaaaatta tagatgaaaa tttcatcgca aaagaaaaaa taccattttc
     4321 tgttactccg atgtacgttc caatataaaa tcttgaaaaa ccaactatta gccatccaaa
     4381 agtgagattc aaagtgagtg ggatagagta tttcagcatg gactttaaaa ataaaaaatc
     4441 aaaagaactc gttgcgaaat attgaaagat ctgccccctg aaaatcaaaa aaatcaaatt
     4501 tataacatta gaaattatga tagagagtaa gagaccaagt atccccatac ccattgtaac
     4561 aacaaaaata gtaaggagta acaggttgat acccgcagcg attataccac tcatcacaaa
     4621 aatctttgat tcacctagtg ctcttacaat atattgaaaa acacttagga taggagtgaa
     4681 aattaattga aaaacaaaca attgataata ctctaaattc gggaaaatca ttctatatat
     4741 tattggtaaa aaaatggcta atatcactgt atttgctata acaaaacaaa tactgttcgt
     4801 cactactttt ttctgaatat ttttttcttt gcctaatccc atgcgtaaaa ttgcttccca
     4861 tattgctcca aaaataactg gagaaagaaa ttgagcaatt gtattttgat aatcaaagct
     4921 tcctaaatcg gcaacagaaa tatatactgc atagataggg attataatga cagatatcat
     4981 ttttgatgat aatgttccta ttgcgtaaat aaaagctttt ttagctattg aatgtgattt
     5041 attactgcta ctatccaacc gtatgacctc cctcaactca catctataga tgactttctg
     5101 gtttaattag aactacctaa attcctctgt atcgtgtgag tcctcgtagt aaaaattttt
     5161 ttgaatatgt gaatagctaa gatcttttca aataaagata tccatgatca actatatatt
     5221 tcttcaatct catcaatcaa tattggcagt cagaatccag ttcacacatc ttgatacaca
     5281 attttgtttt atagaaattc ttttagttat agaaaatatc tattcggcga gaaagttcgt
     5341 cacgtttgaa agtagaattt cctaaaatac ctaacaaagc taaaaaaatc gtatgaatta
     5401 cccatcttca atattccttt caaaattaac tcaaataata cactgtatac cattcaacga
     5461 attttttaat gccctcatcc aaggttatat tcggtttaaa gttgattttt tcctctaaat
     5521 cttcaatatc ggcataagtt ctaacgacat cacccggctg catgtccaaa aaaatcttgt
     5581 tcgctttaac acctaaatac ttttcaattg tttcaacaaa ctccaacaat gcaaccggct
     5641 tattatttcc aatattgtat atcttatatg gtgcccaact ttcactactc aaatcatcga
     5701 tgtctgtcca gtcggagttg ggttcaggta ctttattgat taatctagtg attccctcta
     5761 cgatatcatc gatgtaagtg aaatctcttt ccatctttcc atggttaaaa atcttaattt
     5821 cttttccaga taaaatattc ttggtaaaag agaaataggc catatctggt cgcccaaatg
     5881 gaccatagac agtgaaaaat ctcagcccag ttgttggtat tttataaagg tggctataag
     5941 tatgagccat taattcattc gattttttgg tagccgcata aaggctaact ggatgatcca
     6001 ccgaatcttc tgttgaaaac ggtactttcg tgttcccacc atatactgaa ctagatgatg
     6061 catataatag atgctttaca gggaagtttc ggcaggcttc aagaatatta agaaaaccga
     6121 taatattaga atcaatataa gcataagggt tttcaataga atatctaaca cctgcttgag
     6181 cagctaaatg aattactatg tcaaaacctt cactttcaaa tagagaatct aatttttctt
     6241 tctctaatag atccattctg ataaatttaa aattattata atcgtacagt atcgttaatc
     6301 gatcttcttt taattggaca tcataataat cattgagatt atcaatcgct acaatttgat
     6361 tttcagtttc cttgagtaat tttctagaca aatgaaaacc aataaatcct gctccacctg
     6421 ttattaatat tttcattttt attcatccac ctttttctga aaggaaccaa tagggttaaa
     6481 cccaaaattg ctttcttctt tatactcgta ttacatttat tatttaggca taccccataa
     6541 tttaagatat aacgaagttt atgatactat gcgtcttctc cattcactca aaaaatataa
     6601 cttaattttt tatgacttta aaaaggaaat cttctatctc caaatattta ctaggatttg
     6661 aaagaatagt ttagaaatca tttagggcta ataatgactt atgattctta atttagcgct
     6721 tttatataca ttattgccta aggtagtcac ttccttcatt gcatgtccgg acttccacaa
     6781 cacgtaagga aatgcgagct gatctcgccc actttctgag ttcaaatact ctctccacca
     6841 caaatctaga agattctcag cgattgaatt atttaaatca actaaaataa ccgtggcttc
     6901 agccaatcca aaattatcag gaaatccttc ttctctgtac ttactaattt gctctataat
     6961 actttcctta ttacctttgc caactgcaat taatgcatct gcctcagaat ataaagattt
     7021 tctttcacta tgtttatgca tacttaaccc aagtttggaa gaactgttca gtaatccggt
     7081 aatatcagaa gttattgtta cattaccatc aacatacaaa gtaaaatcgt agtcagtaaa
     7141 tagctcatta ggatgaaatt taatatatct attgatcaaa atattatttt ttaattccga
     7201 tatatattta ggtatctctc taatattcca atgctcactt gtaatcacat tatctgtata
     7261 caaatagtaa tctaccaatg gatgagaaaa atccggttct ttaatagaat cataattacc
     7321 agtgatacaa ctatacacag caatcctttt aggtgttcct tgattagtta actctttttt
     7381 tcttagttca tcactgcgat tctctctgtt tgaatagtct ttaataggcc ccttaccggt
     7441 catcgattta agggtatatt ttgctggcaa cagattatct cgttttttca tttggttaag
     7501 ttgattaatt ttatttcgta ttttcatgcc taaaatagaa ttattttttt gatttaattc
     7561 atgtatttca agatttcttt tttccaattc attgatagct aaactatata attcttgtct
     7621 tcccataaat ccctcatctc tatttttaag tgctatttat tcttactcaa aaaaatagta
     7681 aacagcctta aaaataatat tttctctaaa taatggtagg attccattta caaaagcagt
     7741 tcctcttata ttgatgaata tcaaacacac aatgataaaa aagaaatacg caagcaagta
     7801 gatataattc tttacttttg ttctcttata attactcatt aatacactgg cataaataat
     7861 ataatttaat acaaatatat tttgaataat tctaataaaa ttattactta taagtaagaa
     7921 aactatacta gtagaagcta acatattgat agaaaatata tatgagctta agctgataac
     7981 ttttttttcg taaatattca tttttgataa tttatgaact aaaaaaagat ttgctgaaaa
     8041 aaagagagca aacatcacta cgtgagaaat cgatgtactg tttctatcaa aatatgcatc
     8101 atacttcgta tttataaata ttgaactgat ataactttgt ccaatagaga ataggagcaa
     8161 gctaaggatt gtaacatatc cagtaatctt tttattaatt tttacaataa aaaaagggag
     8221 ataaaaatat gcaagattat ggaacagtcc agccactaag ataaaaaaaa tatacttaaa
     8281 tatagctttg ctgcctcgca atttagttag atgataaaaa gctagtaata tgaatatcaa
     8341 tgcgctaaac atacgtactt gtattgcttg tgaagtaaaa ccaaaaataa aaaacaagaa
     8401 caaaactaaa aaaacattag ttgtgaataa tctgatgaca tacaataaag ctgagagtaa
     8461 gacagtagaa ataatcaata aaaaaatctg atactgactg gaaataaagg tacatacgta
     8521 cataacagct ctgaatcccg gttcaatact atctgaacta aagtccatac caaattgtgc
     8581 tatcccatta tacaagacag aatatgcata ataatcagcg ttttgtgtgt taaatgccat
     8641 gatgatccac attatcaaaa gtagcacccc agacaaaatc ttgttcgatg tactccattt
     8701 tttttgtgaa acactctttt cttgattaat ctccaatgac gcctctgtat ccatctcgaa
     8761 ccccccttat agccgctcta aatctactga gcttatcagt ctcaaaagct attgcaataa
     8821 aaaatttcaa taatctttta ttcataaggc gggaaaattc cttatcactt ttatacattc
     8881 ttttcaccaa tgttgaattt cttgcaataa aatactttcg tgttgaatta tgattgtcta
     8941 ttttaatttt ttttgatcct atttttaaat tttctccatc tccaacgtga tgataaaaat
     9001 agacttgatt tgttacataa atgttatagc cattatttgc aaccctttta caaaattcaa
     9061 catcaatctg atcaataaaa aattcatcct tcatatttcc aacatcgtca attaattcac
     9121 ttttgaaaaa cattccagag gaatttgcaa atgctatttt catggaacca ctagttgaag
     9181 caaagtgttt ttttacgtat ctccctctct catttttgca ggtaaaagag acagattcat
     9241 cattgctatt ctcaaagtaa ttgggaacaa taatcccaat gtccttatct ttcgcttcaa
     9301 tattggtaaa ctcttctaat aattttaaag aaagattctt ttgtatgatg gtatcttgat
     9361 ctagtaaaag gatataatca catttctctt ttttggcaat ttcaatacct atgttttgag
     9421 ctgtcgcaag cccaatgttc tcattcattt tttttaaaat taagttttcc atcatttcaa
     9481 attgaaaaga gttaatatta tctgagccgt tatccacgat aataagtttg ttctgtttct
     9541 cttgtattaa cgtatccact aataacttta tgttattatc tggattgtag gtaacaataa
     9601 ttatcccaat tttatttttc atcgttcatc accttgtaca cttcattcca tttcattttc
     9661 aatacttgct cagagaatat agtggcgtaa atttttctaa cattttcatt tatgttttta
     9721 ttacactgat aaaatttcaa catctcattt tcatcaacgg tactattata attgattccg
     9781 acattatatc ttttaactat ttctttcgta tctcctgata aatttgaaat tataggtaat
     9841 ccaaacctaa aatactcaat cgatttcaga cttaaaccaa ttatggtatt tgacttaaat
     9901 aaatttagtc caaaatgaca tttatcgagt ataacttttt tttctgcatt gtcatatata
     9961 acaccgcagt caacaaattc aatatgattt ttttcacaaa tatcagctaa tttagttttg
    10021 ctttcacctt ttccaataaa gtaaagattt attttgtttc caaattttct tttgcatgtt
    10081 ttcaataatt cattaatcgc ttctaaatct acgatattat taatcgtacc taaataagca
    10141 aggttcaacg tagactctaa gcttttattg actattttct ctccataatc attttggtca
    10201 tctacattga aagaacatgg ataaatggtc atattttttg attctccgga aatttttatg
    10261 aattttttga aataatcgca ttctgttata actagactag aattactgag atattgatct
    10321 cgtagctttt tccataaatc agtaaaaaat ttatatttgt tccctattcc cggcattgac
    10381 tctggccata aatcatacac atcaaaaata actcgattgc atctactaaa cttagcaata
    10441 aaaaaaacta aggtattagg tggtattcta caataaataa tttcaggctt ttcttttcga
    10501 ataaataata atgtttttat tgaaaaccat atatgagata aaattcgcat tacggatata
    10561 ttttttttat atccgatcgt ttttatcaca tgacgatttt taatcatatg cctttcttta
    10621 ctggatagaa attgttttct tatatgtgag taatcagata caacattaaa atattcgata
    10681 ctgttttccg tcagaatttc ctctaatata ttcgttcgac tgatataatc aaaaggatga
    10741 ataagcagcc actttttttt attctcactc atctatcttc gcaccctcaa atttctcagt
    10801 agtcccactt gctactgatg ttattccatc acggacaata actttcttta gcgttaaaaa
    10861 aaatattttt atgtctttca tcattgaaat gttctccaca tattcaatat ctttttcaaa
    10921 tttttctttc caactaattg cattacgacc actgacttga gctaatccgg ttaaacctgg
    10981 gcgcacaaaa tgtctttttc gttgttcatt actgtatagt gaaagatact caactaacag
    11041 aggacgcggt ccaataatac tcatatctcc ttttaaaata ttccataatt ctggtagttc
    11101 atcaagacta gtcgaacgca atattttacc aaattgagtc aatctgatat cgtctgataa
    11161 taaattacct tcttcatctc tttgatctgt cattgttcga aatttataca tcagaaaaat
    11221 cttttcatgt tttccaggtc gttgttgttt aaagatcact ggcgatccaa gctttattcg
    11281 aactaggatt gcaacaaacg tcatcagtgg ccataacatt attaaaccta aaattgaaaa
    11341 aagaatatct atcaaacgtt taaagaactt ttcgtagata cctctattag acattttgca
    11401 tcactcgctt aattgtatta gttactcgat acaaatcatc atcggtcatt ttagaatctg
    11461 aaggtaaaca gatacctttt tcaaacaatg tctgagcaac atctgtacca atatactcat
    11521 acttatcgaa aactggctgt aaatgcattg gtttccatat cgggcgggct tctatattat
    11581 ttttatctaa ctcatcaata agatgattcg tatttattcc ctttactgtt atgacactta
    11641 accaataatt tggttcattc caattatttt ctggcatgaa ttgtatattt gacaatttag
    11701 acaattcttt tttataaaaa ctatgaatat atcgtttttt ctcaattctt tcatttaaaa
    11761 ctttcaattg tcctcgaccg atacctgcaa cgatattgct cattcgataa ttatagccaa
    11821 tttcattgtg ttgataatgg cgtgccttct cacgagattg cgtagcccaa aacctcactt
    11881 tttccacctt ttctttgtca ttagacacaa gcattccgcc acctgaagtc gtgattatct
    11941 tatttccatt aaaagaataa attccatagt cgccgaatgt accagtatat tttcctttat
    12001 atgttgttcc taatgattct gcagcatctt caattaaaac aacattatgt tctttgcata
    12061 ttttagtaat ttcatctagt tcagctgata aaccgtacaa atgcactact aatacagctt
    12121 ttgcgttagg atatttttct agcgctgttc gcaaatgttc agggttcata ttccaagttt
    12181 cgtaatcact atcaacaaat actggaatag ctccttgata gatgattgga ttggcagtag
    12241 ctgagaacgt caaagactga caaatcacta tatcatcttt accgacccca gccgctttta
    12301 aagctagatg tatagctgct gttccagaag atagtgcagc tgcatgacta gcaccgacat
    12361 attctgctaa ttcctcttca aaaccattga cattcatacc caaaggagcc acccaatttg
    12421 tatcaaatgc ttcttttaca tactcttgtt catatccttc atcactcata tgaggagatg
    12481 ctaataatat tcgtttattt tccaacttaa tcccatcttt ctatgacttt ggtaggtacg
    12541 ccaacatttt tagtcttatt attaatattt tttattacta cacttcccgc acctataatg
    12601 ttcatatttc caattcttag attttgtatt attttagtac ctactccaat ttcattttta
    12661 tctcctaata gaacatgtcc tgaaatattt acacttggaa aaattgaatt ataattaccg
    12721 atttgagtat catgtccgat agtagagccg atattgatca tattgaaatt tcctaaaact
    12781 acgtcagcag tgtaagtcgt atagggcatc aaaatattgc caattcctaa ctgaacattt
    12841 atgcccacta gtgcacttga tgcaactaaa ttagggaaaa tcaatttatt atttttattt
    12901 atcttttgat atattttctc tttgatatct ggcgaagcga ttcccagaaa aatagcagtt
    12961 tcttcttcta attctaataa cgagtctatt gttcccaata cagtttttcc cactaattct
    13021 tgattttgca tttttaacga atcatcgaca aaaccaatca attcatatct agagaaactt
    13081 tctagtagaa aagcaatctc tttgccaaat ccaccagctc ctacaataat tgctttcact
    13141 ttactccccc tacttattcg aagcattcgc aaaagtgaca atgtctttag ccaattgttc
    13201 atcgtcttgc ggcaggctct tgacaaattc catcactgtt tgcatggaat aacctttgat
    13261 gtttcccaca aagatcttct cgtaaactgc ttcatcgttt ctttccttat ctaacaatag
    13321 ttcttcatat agtttttccc ctggacggat acctgtttca atgatttcga tctcgtcttc
    13381 gctatatccg ctcaatcgga tcatgttttt tgctagatct acgattttca ctggttcact
    13441 catatctaaa ataaagattt cgccgccttt tgctaacgcc ccagattgaa taactaaacg
    13501 acttgcttca ggaatcgtca tgaaatatcg ggtcatacga aagtctgtta cagtgactgg
    13561 ccctccttga gcaatttgtt cccggaatac tggaatcaca ctaccgcgag aaccaaggac
    13621 attcccaaat ctgacagctg agaatttcgt acatccttct tcattcaacc cagtcacgat
    13681 catttcagcg attcgttttg ttgaacccat gacgtttggc ggattgttgg ctttatctgt
    13741 cgagaccatg acgaagtttt ttactttcgc tgctttggct gcttctgcta cattttttgt
    13801 accgaaaata ttgtttttga ctgcttcttt tgggttatat tccatcaatg gtacatgctt
    13861 atgagcggct gcatggtaga cgatatctgg gtggtattgt tccatgatct cattgatttt
    13921 cttgcgatct tggatatccg caatgatcgg cacgatttct gtaggacact tttgatgatg
    13981 cgtgcgtaat tcacggtcaa tcaagtaaat cgagttctcc ccatgaccta aaagtaatag
    14041 ttttgcaggg tcaaattgga tgatttgccg gcagatttct gaaccgattg atcctcctgc
    14101 accggtgaca agaatgactt tgtttgtgat ctggtctttg atggattcga tatccaactc
    14161 tacctcatct cttcccagta attccactac gtcgatggtt tttaattttg atacgctgat
    14221 tttccctgag gcaagttctt ccatagaagg catcgtattg actttcacat gagcagattc
    14281 gactaactcg aagattcttc gtaatttttt tcttgataaa gaagggatag cgatcgttac
    14341 catttggatg tcatattttt cgatcaattc cggtatatct tttaatgacc ccagtacttt
    14401 ttttcctgaa agataggtat ttcttttatt cggatcatca tccacgaatc caatgacatg
    14461 gatatcttga gccgttttag aaccaagaaa gctgttgtat aaaatacgtc caccttcgcc
    14521 ggccccaacg atcaaggtat ttttagcgga atctgttgat agatacctca tattttttgt
    14581 ttcgatatag atacgccaga tcaatcggct gccaatgatc agtaatagcg aaagtaggta
    14641 tgcaaagatc actaaacgta aactgtattg tttatttatg aaaagcaata tgatgatact
    14701 tgaggccgca cttgcagata acgaaccaaa aatcgcaatg atctctctta aatttgtata
    14761 acgattgatt cgagtaaaaa ctttgaataa actaccatag aataaataaa aaccaatcga
    14821 caaaccgata gagattaaaa taaggtccat tggtatagct acaaacggct tcatgaattt
    14881 agctgctgca atattcgcag caatcaacaa caagctgtcc acaaatacca atgtggcaat
    14941 ttttcttctt cttgttaata caaacaccct acattccccc taaaataaac caaacttctt
    15001 cttttttacc tcttcataga ctggataact gatctcatcc ccgttgatca ggtcctttgc
    15061 gacttgtttc atctgtgcta ctttttcctt accaaagtcc ttggcgattt gctcataaca
    15121 ttcttttaag taaaaggtac gtttagagac cccatgggca tcggaagcag ccatttgcac
    15181 gaggttatgt ttgaccatca ttttggctgt tttctggatg tcttttccaa atacaccgac
    15241 ataacttggt gcggtgagtt gagccaagca tcccatatct aggaatggca gcaaatgatt
    15301 tgggtcttct cgaaaatgcg cgttgcgttc tggatggacg atcactggtg tctttcctag
    15361 ttgtaacaac tcaaaaaaga gccattctgc atataacggc acttccagtg tcggaaattc
    15421 gattagaaga tatgtatcat ctaaatctgt aaataaaatt tcatctcggt ggatgtcttc
    15481 aatcagtgtt ccggtaatac gtacttcttg tccttccaat aacgtcaaag gcaattgtct
    15541 tttctctaat tctgcttgta acgaagcgac tagagaaatg acttgtgatt tttcattgct
    15601 gtattttcca ttattgtgat ggggtgtgca taaaatatgt gtgatccctt gttgaatcgc
    15661 tttttcagcc atggcgatac tggcatctat gttttctgct ccgtcatcga ttcctggcag
    15721 gatatggcaa tgtagatcga tcatttctct tgtctcctct ctttttattt cttaattccc
    15781 gtagtaatag ccagcatctc tgctgtgttc tgctccattg tatacaacac caaggactcg
    15841 cgcttgtacc atatctaaca gttcttttgc tttagtcaat gattcttttc gtgacgtatt
    15901 ttcccgtacg accaataagg tgccatccgt ttttgaagac atgatctgtg catctgttac
    15961 ggcaacgact ggtggcatgt cgaaaatcac tacatcaaat agttgtcttg cttctgctaa
    16021 aatctgatcc attcttggcg aacttagtag ttctgatgga tttggtggtt taggtccact
    16081 tggcagaatc gacaaattgt cgactggtgt tcgttggatc tcatctgcta cacttcctga
    16141 tgaactaaga acagtactta atccgcttgc gttgttcaac ttgaacgttt tatagatgac
    16201 gggcttacgt aagtctgcat cgactagcag tacccgttga ccagatttgg caaaaacaac
    16261 ggcaatgttt gctgcagtgg tggattttcc ttctccagga cctgatgaag tcacgacaat
    16321 cgttttgatt tgctgaccag ctgcggaggc aaactggata ttcgtccgga tcgtacgata
    16381 ttgttcggcg attggtgaag atgggtttgt taatgtgatc aaactgactg catgagtttg
    16441 agttgctttt tgtttctgtg ttcgtgccat ttttcttcct cctagactct tgagcggctt
    16501 ctgcgtgatg gggctgtttt atcgtttgta gcttttggtc gtgcaggagc tgatcctttt
    16561 ttacggatac cagcgttcaa ttcttttgct gacatttctg gaactgttcc taagattggg
    16621 aatcctaatg tatccgtcac atatttttca tctttcactg tccgatcaag taattcgaat
    16681 aagaatgcca gacctacgcc taccatcatt cctaacacta agccaatcac tagattcaat
    16741 ttattatttg gcgaaacagg tgtcgtattg gcaactgcac ctgaaataat cgagatttta
    16801 tcgacattca tcacgtcttt ggcgttttct tggaaaactt gtgaagttgt attagcgatc
    16861 tgttgagcag tcactgcatt cgtgcttatt gcctggatcg agaacatttg tgaattttgt
    16921 gactgattga cggagatcgc atctttgatt tgtccagcag tcattttcac attgtcttct
    16981 gtttctaaac gatctttgac ttcatttagt actaaatcac tgacgatcat atctttatac
    17041 gtattgatca tttgcaggtt cgtattgaca tcattgacat ttgctgtgtc tgattgtggc
    17101 agtgtcacga tcaattgtgc ttgtgaactg tattttggtg tcaagatgaa aaatgttacg
    17161 attcctgaga tggccaagcc agcaaacatt gagatgatga ttgttaccaa gtgtttgcgt
    17221 aatgtttcaa aaatttcttt caagctgatt gtctcttcca ttttttctcc actttcctat
    17281 ttattctcta gattcatttg atcttttaat tcttttttca cacgatcaag ttcttgatcg
    17341 ctgacttttt gataggagat attatcttgc atgaagcctt ctccttgcag ctgatcttgc
    17401 ttgatcgtac caaatgcctc ccgataatct aaagcgattt ttttcatttc atcaaagctc
    17461 atgtctgttt tcatattcga ctctagagca ttcaaaacgg attgatagtt gctgacaccg
    17521 tttaaactca atactttttt tgctacacct tctacgatct ttctttgacg ctcttgtcta
    17581 ccatagtcac catttggatc ttcataacgc atacgagaat aagataatgc ctgatccccg
    17641 ttcaatgtaa ttttaccgat tggaaagtca tagccatctt gtgagaaagt gaggtcatta
    17701 ttgacttcga taccaccaac tgcatcaacg agttccttta gccctttcat attgatagag
    17761 acatagtgat cgattgggat gtctacatat ttttgtaggg tatccatcgc catggcagct
    17821 ccgccgaatg cgtaagcgtg gttgatcttg tcttttgtgt cacgacctac gatgtcgaca
    17881 tacgtatctc gaggaatgct gacgatcgtt gtctgtttgt cttcaggact gactgtggca
    17941 accatcatcg tatctgatct tccttgatcg acccgaccta aatctccagt atcaatgccc
    18001 atcaatagaa cagagaaaga ttcttgtttg tccagatcaa ctggtttcgt tcgttctcct
    18061 tgggttcgtt ccactgattc gtaagttttc tcaatagaat gtgagagatc cagatataat
    18121 tttgctccta ctcctacaat tgctaatact aatacgataa gaactgctaa aataatcaga
    18181 aatatttttt tccctcttga ttttcttctt cgtcttgcca tagtttcctc cgtttgctaa
    18241 ccttgcttga atcaacgttt taactgtcaa taacttatat tgctatagcc catttgctga
    18301 gcaacagttt gtgcttttgt tgcgtatgct gcgcttattt tttcattccg gatctgctct
    18361 atttgactga gcgccgtcaa atattgatcg taagtagcgg tggcagtcac ttgaccatcc
    18421 ttcaacatcg tatcgaataa ctgatctagt tgcgtgactt gcgcgatctg agtatcagcg
    18481 aatcctagat attgcataac aaccgttttc caaggactat ctttaaaaaa gctcatattt
    18541 tcacgtacac gagcgacatc tgcacttgtc accttttctt tgatgacgac atcgtctaca
    18601 gcttgctgcc agtttgatac atttttagta aataaatcgt tgacagctgt ctggatcttc
    18661 agttttgatt ctgcactatc taactgtgtc acgattgctt tcttctcatc ttggattgca
    18721 acagcttctt taggcaattc tgattctttg atgtcgtaat catctgctga aagtttgaca
    18781 gaggatagct tatttgacaa acttgtgatt gtttcttctg ttatttcagg gtttagaaaa
    18841 tttttttctt ttgtactata cagcttgtct acttcttttg ataaagaagt caaggtgtct
    18901 ttttgattgg tgatggcaga ttctgcataa ttgatccgtt gctgatgttg ccgctgatta
    18961 ttgatatggt aaccaaacaa acagatcgca atagcacctg cacctaccgc cacagcagtc
    19021 aatgacttga cgaatggctt ttccatagat tcactcctaa gtattgatga tagataaatt
    19081 aagatataat tcacatacat aaaaatgaca gctttttatt ttaaaaaaca taatta
//
LOCUS       DAZULR010000046        18583 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.047, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000046 DAZULR010000000
VERSION     DAZULR010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18583
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.047"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            154..237
                     /locus_tag="ACG8ZV_002055"
     CDS             154..237
                     /locus_tag="ACG8ZV_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031556 - transcriptional attenuation by
                     ribosome [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HFS4997346.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            362..1099
                     /gene="erm(B)"
                     /locus_tag="ACG8ZV_002056"
     CDS             362..1099
                     /gene="erm(B)"
                     /locus_tag="ACG8ZV_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HFS4997347.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(1362..2225)
                     /locus_tag="ACG8ZV_002057"
     CDS             complement(1362..2225)
                     /locus_tag="ACG8ZV_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HFS4997348.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAL
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTP
                     PIPKTPKLPGI"
     gene            complement(2227..2499)
                     /locus_tag="ACG8ZV_002058"
     CDS             complement(2227..2499)
                     /locus_tag="ACG8ZV_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HFS4997349.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
     gene            complement(2516..2725)
                     /locus_tag="ACG8ZV_002059"
     CDS             complement(2516..2725)
                     /locus_tag="ACG8ZV_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HFS4997350.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
     gene            complement(2824..3720)
                     /locus_tag="ACG8ZV_002060"
     CDS             complement(2824..3720)
                     /locus_tag="ACG8ZV_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFS4997351.1"
                     /translation="MIQYYYTKKEWGVVMEKEKLKILEELRRILNNKNEAIIILNNYF
                     KGGVGKSKLSTMFAYLTDKLNLKVLMIDKDLQATLTKDLAKTFEVELPRVNFYEGLKN
                     GNLASSIIHLTDNLDLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIII
                     DTVPTPSVYTNNAIVASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFV
                     PYLVDTDSATIKSNLEELYKEHKEDNLVFRNIIKRSNKVSTWSKNGITEHKGYDKKVL
                     SMYENVFFEMIERIIQLENEKE"
     gene            complement(3890..4383)
                     /locus_tag="ACG8ZV_002061"
                     /pseudo
     CDS             complement(3890..4383)
                     /locus_tag="ACG8ZV_002061"
                     /inference="COORDINATES: protein motif:HMM:NF024676.4"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(4459..4590)
                     /locus_tag="ACG8ZV_002062"
                     /pseudo
     CDS             complement(4459..4590)
                     /locus_tag="ACG8ZV_002062"
                     /inference="COORDINATES: protein motif:HMM:NF024804.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
     gene            complement(4866..5660)
                     /locus_tag="ACG8ZV_002063"
                     /note="aph(3')-IIIa"
     CDS             complement(4866..5660)
                     /locus_tag="ACG8ZV_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HFS4997352.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            complement(5753..6295)
                     /gene="sat4"
                     /locus_tag="ACG8ZV_002064"
     CDS             complement(5753..6295)
                     /gene="sat4"
                     /locus_tag="ACG8ZV_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HFS4997353.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            complement(6292..7200)
                     /locus_tag="ACG8ZV_002065"
     CDS             complement(6292..7200)
                     /locus_tag="ACG8ZV_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HFS4997354.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            complement(7233..7967)
                     /locus_tag="ACG8ZV_002066"
     CDS             complement(7233..7967)
                     /locus_tag="ACG8ZV_002066"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFS4997355.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            complement(7948..8817)
                     /locus_tag="ACG8ZV_002067"
     CDS             complement(7948..8817)
                     /locus_tag="ACG8ZV_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HFS4997356.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDENRNNLVVPPGAWGDWVNGGGWLVINGCHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGAEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            complement(8832..9056)
                     /locus_tag="ACG8ZV_002068"
     CDS             complement(8832..9056)
                     /locus_tag="ACG8ZV_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4997357.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGEEIKISNE"
     gene            complement(9199..10743)
                     /locus_tag="ACG8ZV_002069"
     CDS             complement(9199..10743)
                     /locus_tag="ACG8ZV_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018659190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFS4997358.1"
                     /translation="MVIPARKRVGSTAAKEKIKKLRVAAYCRVSTETEEQNSSYEVQV
                     SHYTEFIKKNNEWEFAGIFADDGISGTNTKKRDEFNRMIAECMDGNIDMVITKSISRF
                     ARNTLDCLQYIRQLKDKNISVYFEKENINTTDAKGEVLLTIMASLAQQESQSLSQNVK
                     LGLQYRYQQGKVQVNHKRFMGYTKDEDGNLTIVPEEAEIIKRIYREYLEGQSLVGIGR
                     ALEKDGILTAAGKPRWRPESVKKILQNEKYIGDALLQKTVTVDFLTKKRVKNEGHVPQ
                     YYVENSHEAIIPKELFLQAQEEIHRRSNIYTGEGKNKRIYSSKYALSAITFCGDCGDI
                     YRRVYWNIHGRKEFVWRCVTRIEQGPEVCKNRTVKEDELYGAVMTAINKLLAGGNNMI
                     KTLEENIHAVIGETTEYQISEINNSLEEKQKELIKLANKGQDYDHLADEIDELRDKRQ
                     ILLVEDASLSGENERINELIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEGHFVIAFKS
                     GIEMEI"
     gene            complement(10763..11179)
                     /locus_tag="ACG8ZV_002070"
     CDS             complement(10763..11179)
                     /locus_tag="ACG8ZV_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HFS4997359.1"
                     /translation="MAYIPYGYKIQDGVVTVDEKAAGQVKVFFEKYISGLSLTVAGEQ
                     AGIEKTHSVMGRILKNVNYLGNDTYPAIIDKEIFDKAEEVRDKRAKDLGRVVELAAFT
                     SPPPKERFKMKKADNKMPVDPFERAEYLYSLIESEE"
     gene            complement(11180..11677)
                     /locus_tag="ACG8ZV_002071"
     CDS             complement(11180..11677)
                     /locus_tag="ACG8ZV_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombinase"
                     /protein_id="HFS4997360.1"
                     /translation="MLFLRDGEIKATLTTMMNKLAFSHKLILEPLFKSVSQIDEESDC
                     ERMDAIDKLMEQLLEERNTLIALMSKGFLEPALFNQERNVLDSEIKNLTTEKTNLVTN
                     SASGVLRANEIKDLINYVSADNFNGDYTEELFEEFVVNIIVNSRDELTFNLKCGLSLK
                     EKVVR"
     gene            complement(11988..12665)
                     /locus_tag="ACG8ZV_002072"
                     /pseudo
     CDS             complement(11988..12665)
                     /locus_tag="ACG8ZV_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
     gene            complement(12665..13282)
                     /locus_tag="ACG8ZV_002073"
     CDS             complement(12665..13282)
                     /locus_tag="ACG8ZV_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFS4997361.1"
                     /translation="MAKIGYARVSSKEQNLDRQLQALQGVSKVFSDKLSGQSVERPQL
                     QAMLNYIREGDIVIVTELDRLGRNNKELTELMNQIQIKGATLEVLNLPSMNGIEDENL
                     RRLINSLVIELYKYQAESERKKIKERQAQGIEIAKKKGKFKGRQHKFKENDPRLKHAF
                     DLFLNGLSDKEVEEQTGINRRTFRRYRARYNVTVDQRKNNEKRDS"
     gene            complement(13296..13466)
                     /locus_tag="ACG8ZV_002074"
     CDS             complement(13296..13466)
                     /locus_tag="ACG8ZV_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997362.1"
                     /translation="MKKFIYRVLENDEVVAIFNEQQYAQDFIAYEKTISDKQFEIEKV
                     DIADWLLQPREF"
     gene            complement(13814..15304)
                     /locus_tag="ACG8ZV_002075"
     CDS             complement(13814..15304)
                     /locus_tag="ACG8ZV_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HFS4997363.1"
                     /translation="MNIPFVVETVLHDGLLKYKFKNSKIRSITTKPGKSKGAIFAYRS
                     KSSMIGGRGVVLTSEEAIQENQDTFTHWTPNVYRYGTYADENRSYTKGHSENNLRQIN
                     TFFIDFDIHTAKETISASDILTTAIDLGFMPTMIIKSDKGYQAYFVLETPVYVTSKSE
                     FKSVKAAKIISQNIREYFGKSLPVDLTCNHFGIARIPRTDNVEFFDPNYRYSFKEWQD
                     WSFKQTDNKGFTRSSLTVLSGTEGKKQVDEPWFNLLLHETKFSGEKGLIGRNNVMFTL
                     SLAYFSSGYSIETCEYNMFEFNNRLDQPLEEKEVIKIVRSAYSENYQGANREYITILC
                     KAWVSSDLTSKDLFVRQGWFKFKKKRSERQRVHLSEWKEDLMAYISEKSDVYKPYLVT
                     TKKEIREVLGIPERTLDKLLKVLKANQEIFFKIKPGRNGGIQLASVKSLLLSIIKVKK
                     EEKESYIKALTNSFDLEHTFIQETLNKLAERPKTDTQLDLFSYDTG"
     gene            complement(15347..15646)
                     /locus_tag="ACG8ZV_002076"
     CDS             complement(15347..15646)
                     /locus_tag="ACG8ZV_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997364.1"
                     /translation="MNHDECKTYIKNSLLEIRKLANIYTLETFKKELEKRNIYLETKS
                     DKYFSSEGEDYIYKLIENNKIIYSISGKKLTYKGKKSFSKHAILKQLNEKANQVN"
     gene            complement(16012..16296)
                     /locus_tag="ACG8ZV_002077"
     CDS             complement(16012..16296)
                     /locus_tag="ACG8ZV_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFS4997365.1"
                     /translation="MELAFRESLKKMRGTKSKEKFSQELEMSRSNYSRIESGKSDPTI
                     KTLEQIAKLTNSTLVVDLIPNEPTEPEPETESEQVTLDLEMEEEKSNDFV"
     gene            complement(16815..17300)
                     /gene="vanZ-A"
                     /locus_tag="ACG8ZV_002078"
     CDS             complement(16815..17300)
                     /gene="vanZ-A"
                     /locus_tag="ACG8ZV_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HFS4997366.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(17453..18364)
                     /locus_tag="ACG8ZV_002079"
     CDS             complement(17453..18364)
                     /locus_tag="ACG8ZV_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HFS4997367.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
BASE COUNT         5332 a         3746 c         2840 g         6665 t
ORIGIN      
        1 gattcatcgt cattcctcct gctatctttt tctattattc taccttattt gatagtagat
       61 ttaaaacttt gcaacagaac caaaattttg tataatagga attgaagtta aattagatgc
      121 taaaaatttg taattaagaa ggagggattc gtcatgttgg tattccaaat gcgtaatgta
      181 gataaaacat ctaccgtttt gaaacagact aaaaacagtg attacgcaga taaataaata
      241 cgttagatta attcctacca gtgactaatc ttatgacttt ttaaacagat aactaaaatt
      301 acaaacaaat cgtttaactt ctgtatttat ttatagatgt aatcacttca ggagtgatta
      361 catgaacaaa aatataaaat attctcaaaa ctttttaacg agtgaaaaag tactcaacca
      421 aataataaaa caattgaatt taaaagaaac cgataccgtt tacgaaattg gaacaggtaa
      481 agggcattta acgacgaaac tggctaaaat aagtaaacag gtaacgtcta ttgaattaga
      541 cagtcatcta ttcaacttat cgtcagaaaa attaaaactg aacactcgtg tcactttaat
      601 tcaccaagat attctacagt ttcaattccc taacaaacag aggtataaaa ttgttgggaa
      661 tattccttac catttaagca cacaaattat taaaaaagtg gtttttgaaa gccatgcgtc
      721 tgacatctat ctgattgttg aagaaggatt ctacaagcgt accttggata ttcaccgaac
      781 actagggttg ctcttgcaca ctcaagtctc gattcagcaa ttgcttaagc tgccagcgga
      841 atgctttcat cctaaaccaa aagtaaacag tgtcttaata aaacttaccc gccataccac
      901 agatgttcca gataaatatt ggaagctata tacgtacttt gtttcaaaat gggtcaatcg
      961 agaatatcgt caactgttta ctaaaaatca gtttcatcaa gcaatgaaac acgccaaagt
     1021 aaacaattta agtaccgtta cttatgagca agtattgtct atttttaata gttatctatt
     1081 atttaacggg aggaaataat tctatgagtc gcttttgtaa atttggaaag ttacacgtta
     1141 ctaaagggaa tgtagataaa ttattaggta tagggcacct ctaataacta ccaattaatt
     1201 cacctcaaaa tgaaattaga aaaaaacagc gaaattttta aatctatttc ttatcgatac
     1261 aaattcctcg taggcgctcg ggaccccaac atgaggaaat gtttttataa aaaaagagta
     1321 gttaccgttt tttggtaact actcttttcc ttttttaagg tttaaatacc tggaagttta
     1381 ggtgttttgg gtattggtgg tgtaggtagc tgcaagcttt ccattttttg ttgaattgct
     1441 ttaaattcag gggtttcttg gtgttgattt tgaaccattt tttgctctat tctctccaaa
     1501 gtcggttgaa tttctttccc tgatacttta cgatttaatt ctctttctaa ggtctctttc
     1561 ggactaatgg aaggcgtttc taagcttgaa tagagtttca ctccttctct attgtaaagc
     1621 cttatatcgc taaataagcc cgttttatga agggtttcta aattggtcgg taagtttttg
     1681 acaacaatat catgcgcttg ttttggtgtt gccctagctg tcattggatc atctgcatac
     1741 atggtttcat atcgttcaat cgttcctaag tatgattcaa ttttcggtac tgccatgacg
     1801 tatatttttg tttcataacc tttagattga agcattgtgg ctgtttgaat gggaacgtct
     1861 gttgttcgtc ctgttccttc aatcactaaa ttatagcctt gatcgcttaa acggctaata
     1921 agtgcttctg tcatgcgatt cgaataaggg gtaacgtgtt ttactacgtc tttttcatag
     1981 agtttcacta attcgtcaaa atttgggtgc tgttgtttaa aggtatcatt atcaatgaca
     2041 ataacattcc cttgtgtttc ttcaaaaatt gctgatcgca aactggtttt ccctgaccct
     2101 ggttgcccac caagtaaaaa agcggttggc gattcaaccg ctagtctatt tttagttagt
     2161 cgttcaacat tcttttctaa acgatcttca aattgctttt cggtgaagtc agtaatattc
     2221 gccatgttaa gccactttct ctttattcaa aatttgtttt gaatattgat tcattgaccg
     2281 ccaatactca tgaatagctt gtaattcttc aaatggttgt tgaaataaat caacttcttg
     2341 tgccacttct aattgattta aaagattcac ttctagtaaa cgagtatttt tagtatctag
     2401 ttcatgattc aaaacataat ttaatacccg attataaaca cttgccgata actcattaat
     2461 gatttcaatt tcaaatgttt tttcatacgt aactgccatt tcattttcac tccttttaaa
     2521 gtttgtcagg taaatatttc cgtatatatt cttctaaggc ttgatccata acttctttta
     2581 cgtttccgcc attctttgct gtttcgattt ttatgatatg gtgcaagtcg gcacgaacac
     2641 gaaccgtctt atcccccatt atatcttttt ttgcgctgat tggcgtatca tttcgttttg
     2701 ctttctgtgc gcctaaattt cccacgatcg ctcacttctt tctatttctt cttactattt
     2761 attttatcat cacctatcac aaatcacaag tgatttgtga ttaatcactt gtgatttgtg
     2821 attctattct ttttcatttt ctaattgaat gattcgctca atcatttcaa aaaatacgtt
     2881 ctcatacata gacaaaactt ttttgtcata gcctttgtgt tctgtaatgc catttttaga
     2941 ccaagtactt actttattac ttcgcttgat aatatttcgg aaaaccaaat tatcctcttt
     3001 atgttctttg tacagttctt ccaggtttga ttttatcgtt gcgctgtccg tatcaactaa
     3061 ataaggaaca aaaccaatca tatctagtcc agggttaaac tgttcttgca aatcaatcaa
     3121 ataggaaata tagttttgaa tgttgtttgt actttcttct tctgcttgta aagggatcat
     3181 aacgtaatca ctcgccacga ttgcattatt tgtataaacg cttggcgttg gtacagtatc
     3241 aataataata agatcatagt cactttttaa aggtgctaaa agagtagcaa gcaatctact
     3301 ttcattttca aacgtccatg agcgagttaa ttttggcagt aacatcaaat caaacgtgcc
     3361 agggatcaag tctaaattat cagtcaaatg aataatagaa gaagccaagt ttccattttt
     3421 caagccttca taaaaattga cacgtggcaa ttctacctca aaagtttttg ctaagtcttt
     3481 tgtcaatgtt gcctgtaagt ccttatcgat cattaaaact tttaaattca atttgtctgt
     3541 caagtaagca aacatagtcg ataatttgga ctttccaaca ccacctttaa agtaattatt
     3601 caagataata attgcttcat ttttattgtt taaaatacgt cttaattctt caagtatttt
     3661 tagtttttcc ttctccataa ctacgcccca ttcttttttt gtatagtaat attgtatcat
     3721 taagaatcac aaatcacaag tgatttgtga ttaatcactt gtgatttgtg ataagtgatt
     3781 tgtgattaat atataaaagc cctctttaaa gggcttttat atttattttg agaaagatat
     3841 aaaatcaata tatccctttt ccccaatttt tacaacggca ttgtagggca tatagttttt
     3901 tatatgaaag catttgtttt aatatttgtt ccaaagagcc atcatggctt tgacagagct
     3961 cttcttctat gcaaatgctt ttaatccgat ccacacgaaa attcctatat tcatttctta
     4021 gcctgcaaaa ccgattaagt accagttctg ttcataaaac cccagtgata taggctctat
     4081 cattctgctt tccggttctt gccctcctga tgcaggatat tgaattgata ttaccctttt
     4141 attgcagatt gcagtctgaa ttgctgcaat aacgttatcc gccaatgtat ttttctgtcc
     4201 agatgtgctg tacacgttaa tactgttctc caactcctgt gcatagtttt tttcaccatg
     4261 cttcaaaata gatttgattt tatacatagc tgaatcaaaa tcctttataa atgattcatc
     4321 tccatggcaa tttaaaaatt tccctgctgt aatcaatgca cccacttccg ccgctgtaaa
     4381 cattaccggc ggaagtagga agccctctac aagaaaatat ccttttccgg cctcagatcc
     4441 aattggtatt ccggcttctt caagtgtccg gatatctctg taaactgtcc ttaagcttat
     4501 attaaatcgc tgtgcaattt ctttggcagg aattattttt tttgattgca gctgaataag
     4561 aatagaggtt actctgttaa tcctgttcaa attttattcc tcctctgtga cttccataaa
     4621 aagtatatcc tatgcgttct taagctagct gctgttagtg cttctcattg caccctggtt
     4681 ataaaagcca tactcacaaa cctcttcacc aaaactcttt acatctctaa tatagaactc
     4741 tatctagcga acttttagaa aagatataaa acatcagagt atggacagtt gcggatgtac
     4801 ttcagaaaag attagatgtc taaaaagctt gtagttaaag ctttttagac atctaaatct
     4861 aggtactaaa acaattcatc cagtaaaata taatatttta ttttctccca atcaggcttg
     4921 atccccagta agtcaaaaaa tagctcgaca tactgttctt ccccgatatc ctccctgatc
     4981 gaccggacgc agaaggcaat gtcataccac ttgtccgccc tgccgcttct cccaagatca
     5041 ataaagccac ttactttgcc atctttcaca aagatgttgc tgtctcccag gtcgccgtgg
     5101 gaaaagacaa gttcctcttc gggcttttcc gtctttaaaa aatcatacag ctcgcgcgga
     5161 tctttaaatg gagtgtcttc ttcccagttt tcgcaatcca catcggccag atcgttattc
     5221 agtaagtaat ccaattcggc taagcggctg tctaagctat tcgtataggg acaatccgat
     5281 atgtcgatgg agtgaaagag cctgatgcac tccgcataca gctcgataat cttttcaggg
     5341 ctttgttcat cttcatactc ttccgagcaa aggacgccat cggcctcact catgagcaga
     5401 ttgctccagc catcatgccg ttcaaagtgc aggacctttg gaacaggcag ctttccttcc
     5461 agccatagca tcatgtcctt ttcccgttcc acatcatagg tggtcccttt ataccggctg
     5521 tccgtcattt ttaaatatag gttttcattt tctcccacca gcttatatac cttagcagga
     5581 gacattcctt ccgtatcttt tacgcagcgg tatttttcga tcagtttttt caattccggt
     5641 gatattctca ttttagccat ttattatttc cttcctcttt tctacagtat ttaaagatac
     5701 cccaagaagc taattataac aagacgaact ccaattcact gttccttgca ttctaaaacc
     5761 ttaaatacca gaaaacagct ttttcaaagt tgttttcaaa gttggcgtat aacatagtat
     5821 cgacggagcc gattttgaaa ccacaattat gatagaattt acaagctata aggttattgt
     5881 cctgggtttc aagcattagt ccatgcaagt ttttatgctt tgcccattct atagatatat
     5941 tgataagcgc gctgcctatg ccttgccccc tgaaatcctt acatacggcg atatcttcta
     6001 tataagcgta ccggttccaa ttttttcgca gtttaacttt tccgacgcat ttatcgtctt
     6061 ggtagtaaag atatattatc ttatcagtat tgtcaatata ttcaaggcaa tctgcctcct
     6121 catcctcttc atcctcttcg tcttggtagc tttttaaata tggcgcttca tagagtaatt
     6181 ctgtaaaggt ccaattctcg ttttcatacc tcggtataat cttacctatc acctcaaatg
     6241 gttcgctggg tttatcgata tctttcaggt gccctgcttt catttctgta atcactgttc
     6301 ccgcctctct tctatatcag cggcatatgt gctatccagg cagccggttt taccagtgta
     6361 ttttttatac atgtccctgg tatattttgt tatattccta tcatactccg gataggcata
     6421 atgaagcctt tccgccacct caccggatac cgccctgaac aattgatggc atagaaataa
     6481 tgcttcccat atgttttcat aggaatccat ccggtaggtg gacaaaagtt tctcccacaa
     6541 atcctcggat atataccttt caataaactt atagttcttg cctacactta atttaaagcc
     6601 tgtttcgatg ccgaccttcc atgatatcat tctcagcagc tcatggcgaa caatctgatt
     6661 aaaatgatca atagcaaata aaatttcctt acggcacaat cctttaataa cataaggtgt
     6721 tacattccaa aattcattgc agcaatcatc atactccctt gcgcttggct ttcttacatg
     6781 ataatctata tcagtcggaa ctatgtccct tttaattcta caatctttat caattagaac
     6841 ctttattaat ttatcgccct ttaggtaatt atctaactct tccaagggca ataaggtaag
     6901 atcaatttta ttgtaatcat caaatagcat aagataggaa aatccctttt cttcaggtgg
     6961 gaataattcc atatcctccg gcttttgcat cattattata ttcccaaatt gattaagcca
     7021 gtcatcatta gatataaacg gttctatatc acttacaaaa tatgtaatat cataatcctg
     7081 aaattcatct ttaggtatat taatatttgc gcgtgacccc tcaagggtca caattcgaat
     7141 acgttcatcc tgttctgcta aagaaagtac taaatccatc atttcttttt ctgatctcat
     7201 ttacatactc ctcgtttatt ttttctatat tattacatct tcttttttgc cgatacaatc
     7261 agcatcattg ggcgtcgcat ttcatccgcc atccccggaa tatccatcat gttctctggc
     7321 ggctgtggct ccacaatctg atttattata aaactatttg aaagcagtgt atttagatat
     7381 gtggtcagtg ttctatgata ttttgtaacc ttttcttcca aaaacatagc tgtccgtttg
     7441 ccctcataat aataattgtc caccgggaaa tgcagtattt ctcctttttc gttataatac
     7501 cagtcttgtg ttccatgagc agtaaaaaca ggatgttcaa ctgtaaaaac taaattgcca
     7561 ccagccttca gcatcctata tatctttttt attaaattct catagtctgc tacataatga
     7621 aacgcaagcg aacttagtat tacatcaaag ctctcctctg ggaaatccac atcttctatg
     7681 gcacagcatt catattcaat ctgtggaaaa tgggtttttc cttttgctac ttcgagcatt
     7741 ttatgagaaa tatcaacacc tactacagag gaagcaccgt tttccatcgc atatatacag
     7801 tgccatccat agccgcatcc taaatcaagc acacgcttac ccttaaaatc aggtagcatc
     7861 tttttcaaag tctcccattc tcccgcacca gccagtcctt tctgcgagcg actcatttga
     7921 ctgtattttt gaaaaaatat attatcatca tatttgtttt ctttcatctg aactctcctc
     7981 gtttaaaaag ttatttatct ccgatacaat ttcattcact tctttataaa gtttctcggt
     8041 catgtcgtag cattcaaaaa gagaaagacc gagtacttca aaaatatgat taactctttc
     8101 ggcatatttt tcaggtttat attcaaaagt ttcaagcagt tttatagctt tcttttcgtt
     8161 aatgcaataa gcattattac atgcaaatag tacttgattt aagcatgaaa taatacgaaa
     8221 aacatggcct gcaatataat atttatcctc tgcccccgca tttgctttta caaacattaa
     8281 agagaattca gcttcaaata taaaaaagtt catcaagctt ttctttagag cagtagggta
     8341 aatttctgcc tgctttttta attcgcataa gctttcgttc ttagcatata gtattttact
     8401 aatcgctaat tctccacgat acatagcact tatataacca tggggatgcc cggtctgata
     8461 attggcagta acaattcctt gctccgtatc tttgattatt tgttccaccc gttttatatc
     8521 acgtaatatc aagtcaacat gacacccgtt tataactaac catccaccgc cattaaccca
     8581 atcaccccac gctccgggag gtacaacaag gttgtttcta ttctcatcat ccaactctgt
     8641 agcaatttga ttaatcgctg tcaggtcaaa tgagtctgaa ttgtaataga ttccgatatc
     8701 tatatcagaa ttttctgtat gggtgcctct tgcacgtgag ccccctaata cgatgccttc
     8761 tataaaaggc aaagatgata atttctctgt tactatttga ataacattac ctaccatata
     8821 aacatcctcc tttattcgtt agatattttt atttcttctc catctggtaa aataaatgcc
     8881 tgcacaaact tgacacctag cacatcagca atggccttca actcatccaa ggttactgtt
     8941 tctcgttgta attttttatt gaaattctgt ggagtctggc caatacgtct agcaagttcg
     9001 gaaacactta tattcatttg ctcacacagt tctttaatca tttctgccgt agtcatacag
     9061 cacctccaag tttacgctaa gaatattata aaccatttgg ttgataaaca caatagttat
     9121 taaaatatta ttataatcag caagcaaaag aaaacccaca actctactgt agagtcatgg
     9181 gctatttact tctggttttc atatttccat ttcgatgcca gatttgaagg ctatgacgaa
     9241 gtggccttca tagactgtaa cgctctggat tatcttcctt acaagcttat catcatattc
     9301 taaggtgcgg aatttgttct tgcggataaa ttcaatcagc tcattgattc gctcgttctc
     9361 gccactgagg gaggcatctt ctactaaaag gatctgtcgc ttgtctctca gctcatcaat
     9421 ctcatctgct aagtggtcat agtcttgacc cttgttcgcc agcttgatta gttctttttg
     9481 tttttcctct agtgagttgt taatctctga aatttggtat tctgtggttt cgccaatcac
     9541 agcatgaata ttctcttcca gtgtctttat catattgttc ccacctgcaa gtagcttatt
     9601 aatcgcagtc attactgcac cataaagttc atcttctttt acggttcggt tcttacaaac
     9661 ttcaggacct tgctcgattc tagtcacgca tcgccagaca aattcttttc ttccgtggat
     9721 attccaatag acccgtctat aaatatcgcc acaatctcca cagaaggtga tggcacttaa
     9781 agcgtacttg ctactgtaaa ttcttttgtt cttgccttct cctgtgtaga tattgcttct
     9841 ccgatgaatt tcttcttgcg cctgcaaaaa taactcttta ggaataatcg cttcatggct
     9901 attttcaaca taatattggg gaacatgccc ttcatttttc actcgtttct tggtcagaaa
     9961 atctactgtg acagtctttt gcagaagggc atctccgatg tatttttcgt tttgaagtat
    10021 cttcttaact gattctggtc gccatcttgg ttttcccgct gctgttaaaa taccatcctt
    10081 ttcaagggct cgaccaatgc ccactagact ctgaccctca aggtattctc ggtagatgcg
    10141 tttgataatc tcagcttctt cggggacaat agttaaattt ccatcttcat ctttcgtgta
    10201 gcccataaat cgcttatggt tgacctgcac ctttccttgt tggtatcggt actgtagccc
    10261 aagcttaacg ttttgtgaaa ggctctggct ttcctgctgt gccaaagatg ccataatagt
    10321 cagcaaaacc tcacctttgg catccgtggt gttgatgttc tctttctcaa aataaactga
    10381 tatgttctta tccttgagct gtctaatgta ttgaaggcag tctagggtgt tacgcgcaaa
    10441 tcggctgatg gattttgtaa taaccatgtc gatgttaccg tccatacact ctgcaatcat
    10501 gcgattaaat tcgtcacgct ttttagtgtt cgtaccagag ataccatcat ctgcaaagat
    10561 gccagcaaac tcccattcat tatttttctt tataaactct gtatagtgtg agacctgaac
    10621 ctcatagcta gaattttgtt cttctgtttc tgtagaaaca cggcaatagg cagcaacacg
    10681 aagtttcttt atcttttctt ttgcggctgt acttcctact cttttacgag caggaataac
    10741 cattatattt ttctctgtca ctttattcct cgctttctat cagactgtat aagtattctg
    10801 ctcgttcaaa aggatccact ggcatcttat tatctgcctt tttcattttg aatcgttctt
    10861 tgggaggggg agaggtgaaa gcggcaagct ctaccactcg tcctaaatcc tttgcacgtt
    10921 tatctctaac ttcttcagct ttatcaaata tctctttatc aataattgct ggatacgtat
    10981 catttccaag gtagttgacg tttttcaaaa tgcgccccat cacagaatgt gtcttttcaa
    11041 tacctgcctg ttcgccagcc actgtaaggg atagtcctga tatgtatttc tcaaagaata
    11101 cctttacttg acctgctgcc ttttcatcga cagtaaccac tccatcttga attttgtatc
    11161 catatggaat atatgccatt tatctcacca ccttttcttt cagggaaaga ccgcatttca
    11221 aattgaatgt cagctcatcc ctggaattta caatgatgtt cactacaaat tcttcaaata
    11281 gttcttccgt gtagtcacca ttaaaattat ctgctgacac ataattaatg aggtccttta
    11341 tctcgtttgc tcgcaaaacc ccactcgcag agttcgttac caggtttgtt ttttcggtag
    11401 taagattttt aatctcacta tctaaaacat ttcgttcctg attaaaaaga gcaggttcta
    11461 ggaaaccttt ggacatcagt gcaataaggg tattgcgttc ttccaatagt tgctccatta
    11521 gcttatcaat agcgtccatt ctttcacagt cgctttcttc atcgatttgg ctaactgact
    11581 tgaaaagtgg ttctaggatt agcttatgac tgaaagcaag cttattcatc atggttgtca
    11641 atgtggcttt gatttcccca tctcgcaaaa acaacatgga gcaactttct ttatcttcga
    11701 tactatctca acatgtgtcg tggataaggt aagtatgtaa aatggtatgt ggaacatagt
    11761 gatttgctgt aaatgatttg ctaactactt tagttcttta tacaaagtat aaatcggata
    11821 ttttattatt ttttctttta tatcttctga gattaggtca aagtatttgt ccgctaaatc
    11881 agaaaggggt tcttttttca tcacctaatg ggtgatgaag cagaatactt taaagactat
    11941 taaatcaatg ttaggaaaga ctattagtaa aactatgaat tattcaggaa aaaaggttct
    12001 tttttaaagt tttctattgc ttcctggcgt tgataaatga gatataaagt cggtgtttgt
    12061 acacgtccta atgaaaatgt accttgtacg cctttttgtt gtaaattcaa ggtatataaa
    12121 gggcttgcgt tcatgccgat caaccaatcg gcaatttggc gtgtttgcgc ttcttgataa
    12181 aagggatagt aattcattcc tggttgcaaa ttttgaaaac cgcttcggat cacatctttt
    12241 tctaagctat tgatccataa tcttttatac gttttatctt tagaaaaggc atttgcttta
    12301 tggataatcg accaggcgat attttcacct tctctgtcgc tatctgttgc gacaataatt
    12361 gtatttgcct ttttgagaag ttcagcaaca attttaaact gctttccctt atcttttgca
    12421 acttcaaaat cgtatcgatc aggaaaaatc ggcaaagatt caagtttcca attttgccac
    12481 ttttcgtcat aatgacctgg ttctgctaat tccactaaat gcccaaaacc aaaggtgata
    12541 aacgtttcat ctgtaaatag tgggtctttg atctcaaaat aaccgtcttt tttggtgctt
    12601 tgttttaaag cacttgcgta ggctaatgcc tggcttggtt tttcagctaa aataaccgta
    12661 ctcattaact atccctcttt tcattgtttt ttctttgatc gactgtcacg ttatatcttg
    12721 ctcgatacct tctaaacgtt cggcgattga ttccagtttg ttcttcaact tctttatcgg
    12781 ataaaccatt caaaaacaaa tcgaaagcat gctttaaacg tggatcattt tctttaaatt
    12841 tatgctgacg acctttgaat ttgccttttt tcttagcaat ttcgattcct tgtgcctgac
    12901 gttccttaat tttttttcgt tctgattctg cttgatactt gtacaattca atgacaaggc
    12961 tattaatcaa acgccttaaa ttttcatctt caataccatt cattgagggt aaatttaaga
    13021 cttccagggt tgccccctta atttgaattt gattcatcaa ttctgttaat tctttattat
    13081 ttcgtcctaa tcgatctaat tcagtaacaa taacaatatc cccttcacga atatagttaa
    13141 gcatagcttg taattgtggg cgttcgaccg attgaccgct taatttgtct gaaaagacct
    13201 tagaaacgcc ctgtaacgct tgtaattgcc gatctaagtt ctgttctttg ctactgacac
    13261 gtgcataacc aattttagcc attttcaacc aacctctaaa attctctcgg ttgcaataac
    13321 caatcagcaa tatctacttt ttcaatttca aattgcttat cagaaattgt cttttcgtaa
    13381 gcgataaaat cttgcgcata ttgttgctca ttaaaaatag ccaccacttc gtcattttct
    13441 aaaactcgat aaataaattt tttcatttta ctcctcctat tatgcccaac ttaaatgacc
    13501 tattcaccaa gtcaattata ctgctaaaat catattagga caaataggta tactctaatg
    13561 acctataaaa gatagaaaat taaaaaatca agtgttcgct tcgctctcac tgcccctcga
    13621 cgttttagta gcctttccct cacttcgttc agtccaagcc aactaaaagt tttcgggcta
    13681 ctctctcctt ctccccctaa taattaatta aaatcttact ctgtatattt ctgctaatca
    13741 ttcgctaaac agcaaagaaa aaacaaacac gtatcataga tataaatgta atggcatagt
    13801 gcgggtttta ttttcagcct gtatcatagc taaacaaatc gagttgtgtg tccgttttag
    13861 ggcgttctgc tagcttgttt aaagtctctt gaatgaatgt atgctctaag tcaaaagaat
    13921 ttgtcagcgc ctttatatag ctttcttttt cttctttttt tactttaatg atcgatagca
    13981 acaatgattt aacactagca agttgaatgc caccatttct tcctggttta atcttaaaga
    14041 aaatttcctg attcgccttc agtaccttca gcaatttatc taatgtccgt tcaggaatgc
    14101 ctagcacttc tctaatctct tttttggtcg tcactaaata aggcttgtat acatcgcttt
    14161 tttcgctaat ataagccatt aaatcttctt tccattctga caaatgaaca cgttgacgtt
    14221 cgcttctttt tttcttgaat ttaaaccacc cttgacggac aaataaatct ttactggtta
    14281 aatcacttga tacccaagct ttgcaaagaa tggtaatgta ttccctatta gccccttgat
    14341 agttttctga ataggcactt ctaacaattt tgattacttc tttttcttct aagggttgat
    14401 ctaatcgatt attaaactca aacatattat attcgcacgt ttcgattgaa tagcctgaac
    14461 taaagtaggc taaagagagg gtaaacatga cgttattacg ccctattaaa cccttttctc
    14521 ctgaaaattt cgtttcgtgc aataagagat taaaccaggg ttcatctact tgttttttgc
    14581 cttctgtacc gcttaaaacc gttagacttg aacgagtaaa gcccttatta tctgtttgtt
    14641 tgaaagacca atcttgccat tctttgaaag aataacggta attaggatca aaaaattcta
    14701 cattgtccgt tcttggtatg cgagcaatac caaaatgatt acacgttaga tcaactggca
    14761 aagactttcc aaaatattct cggatatttt gcgaaattat tttggctgct ttgacagatt
    14821 taaattctga ttttgaagtc acatagactg gcgtttctaa aacaaaatat gcttgataac
    14881 ctttatcaga tttgataatc atagtaggca taaaacctaa atcaatagcg gttgttaaaa
    14941 tatcgcttgc tgaaatagtt tcttttgccg tgtgaatatc aaaatcaata aagaaggtat
    15001 tgatttgtct taaattgttt tcagaatgtc ctttcgtgta tgaacggttt tcgtctgcat
    15061 acgttccata acgataaacg ttgggtgtcc aatgtgtaaa tgtatcttga ttttcttgaa
    15121 tcgcttcctc ggaagtcaga acaacaccac gaccgccaat catgcttgat tttgagcgat
    15181 acgcaaaaat agcccctttg cttttacctg gcttggtagt gattgagcga attttactat
    15241 ttttaaattt gtactttaac aagccgtcat gaagcacagt ttctacaaca aaagggatat
    15301 tcattcagct gttctccttt cctataaatc ctataaaata ggttgtttaa ttaacttggt
    15361 ttgctttttc attcaactgt ttcaatattg catgttttga aaaagatttt tttcctttat
    15421 aagtcaattt ttttccacta atcgaataaa ttattttgtt attttctatt aacttatata
    15481 tataatcttc cccctccgaa gaaaaatact tatctgattt tgtttctaag tagatatttc
    15541 tcttttctaa ctctttctta aacgtttcta gtgtatagat atttgctaat tttcttatct
    15601 ccaataaact attttttata taagttttac attcatcatg attcatacaa actccacctt
    15661 ctataaatga atacaaaaaa agcaatcaaa cgatttccga ttgattgctt aacaattctt
    15721 aaattcagta gcttagatac ttgaaaactc tctgatttcc ctatataatg atagtacggt
    15781 tatataccgt cttcaaacaa agttaattaa ataacttctt acgagggaag agttcatctg
    15841 actaactgat aagcgttggt ttggcaatct tatcgggcta tgcatttata aaatgtcgtc
    15901 aaacatttta taaatgtgtc atggctcttt tttcgtttct attcagttcg ttgtttcgtt
    15961 atatctagta taccgctttt aaaaaaaata agcaacgatt tcgtgcatta ttcacacgaa
    16021 gtcattgctt ttttcttctt ccatttctaa atccaatgtt acttgttctg attctgtttc
    16081 tggttctggt tctgttggct catttgggat taaatccact actagcgttg agttagttaa
    16141 ctttgcaatt tgttctagtg tttttatggt tggatctgat tttcctgatt ctattcgtga
    16201 ataatttgat ctactcattt ctaattcttg ggagaatttt tcttttgatt tggtacctct
    16261 catctttttt aagctttctc taaatgctag ttccaagttt ctcccccctc tttttgtgta
    16321 ataaaattca cgctttattt aaattatagc ttttaatatc ttaataaaca agtgattaat
    16381 cacttgtgat ttgtgattat tccaaaagta ggtaatttca ccaacctttt tcaaaagttt
    16441 ttatcgacga ttattggact ggatcgtgtt tcctaaagcg attctaagcg catgtttaat
    16501 tttaaagtgg gtaattctct ttaaaacgtc ctacaaagat tcaaaaaaag catggctgct
    16561 agtgggggta ccgtcaggaa aatgcggatt tacaacgtta aggaaattta ttaaagagac
    16621 caattcctca gcactaaaat tgataattgg gctttctttg ttactatagt gttaggtaag
    16681 ctttttactt tatcaccggt tttcccctca cttcacacct acgggcgagt ttccccacat
    16741 cccgttttcc atctaatcca attcattcaa tatctttatg tgtatgaaag atcagattgc
    16801 ttgatttaga catcttacac gtaatttatt cttaaatggg tacggtaaac gagcaataat
    16861 acgagcaaaa gtatacctac aaaaataata actctgtcta attttttttg attcatatgc
    16921 ttattgctta aaccatataa tttcagtcca agaaagcctc caacagtatt tgtaattaca
    16981 tctgttatgt ctgtcgctcc aatagcgaag ataaattgaa ttatttcaaa agtaagactt
    17041 aaaaccagta caaaagcaaa cttaggtaaa aatccgattt ctttaaaatt gacattcaaa
    17101 agcaagccaa atggaataaa gattataaca ttatctatca tctctctgaa attcccagta
    17161 gcagtaaatg gagtcaagtt aagacttctt tgatgataat taaatactga taaaatattg
    17221 tattgtaatt tgaataacac taaccagatt agtgtcacta aatataaagc tagcaatcct
    17281 ctagataata tttttcccaa tataatttcc tctaattctt ttgtttaagt tgtatcatta
    17341 gtatagcaat gtcctagtta acgtgggttt taaattaaaa agctaacgtt accccaaaag
    17401 tgctagtaca ataatgctgt tcattaattt cgttggtttc attccgccat ccttacctcc
    17461 ttgaattagt atgtgttgat ccgggaaaca ctgtcacaat tacaccgtct atattgtttc
    17521 ctgatatctc ataacgaaga ttagtcggca catgaatggt ggtattttta gtaacaggat
    17581 aataaaagat ctcatatttt tccccattta cactaacaga aatggttttt tcttctttta
    17641 ggtaatccat atattcctcg agaacgaaat tcttttcttt cataatcgca ctatgtggta
    17701 aaccaacata gcgaatatgc catggttcat attgaattcc tgttaactct gttttgtcct
    17761 ctggataacg taaaatgaac ccgtatttcc aagcattttc ttctatccac tttccttcag
    17821 gggctcgttc cattttcgtc aagcttgatc ctacatctag tgataaacct gaattatgct
    17881 cactataacc tgctggtaag gcatactcag cccccatttc ttggtaaagc acactttgct
    17941 catcaaagtc tcgatagcca ctattaataa taaaatgact aacgccaccc tttacagcat
    18001 cattgaccat ctctgaaaat ttttgtgcta tttcttttga catataaata ttactatcaa
    18061 gcaacccgta tccatttatt aattcgtcat gtttagataa attcacgata tctgacttca
    18121 cactttcttg gcgaacagga tatttactat tgattaatag cagatttcct tgataaacct
    18181 gttcttctgt aattgttttc tcttgggtat tttcagaagt cccactattt tctaaatgtt
    18241 ctttgggatt ttgatcataa ttttgaaatt cgactttttc ctgagaaaac agtgcttcat
    18301 taacgtagtc ataacctaag tatattaaga ataacaataa caataaaaaa aacaacttct
    18361 tcattttcag tctcctcctt aactatatag ttggaagtat gaaatatttc tagaatcttc
    18421 cccttaaacg gcacaatctc gtttgagatt gtgccgtttt gccccgtaaa ttacagtcaa
    18481 ttatttcgcc ctactggatt tactattatc accaatgtag atgaattttc ataagtgata
    18541 cccatgctga atttaacgag gctgaactgc ctgttgacaa tgg
//
LOCUS       DAZULR010000047        18191 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.048, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000047 DAZULR010000000
VERSION     DAZULR010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18191)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18191)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18191
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.048"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            1..369
                     /locus_tag="ACG8ZV_002080"
     CDS             1..369
                     /locus_tag="ACG8ZV_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HFS4997368.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            549..1490
                     /locus_tag="ACG8ZV_002081"
     CDS             549..1490
                     /locus_tag="ACG8ZV_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HFS4997369.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            1559..2290
                     /locus_tag="ACG8ZV_002082"
     CDS             1559..2290
                     /locus_tag="ACG8ZV_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFS4997370.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            2434..4614
                     /locus_tag="ACG8ZV_002083"
     CDS             2434..4614
                     /locus_tag="ACG8ZV_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HFS4997371.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            4634..5116
                     /locus_tag="ACG8ZV_002084"
     CDS             4634..5116
                     /locus_tag="ACG8ZV_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HFS4997372.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            5132..5893
                     /locus_tag="ACG8ZV_002085"
     CDS             5132..5893
                     /locus_tag="ACG8ZV_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HFS4997373.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            6024..7358
                     /gene="murC"
                     /locus_tag="ACG8ZV_002086"
     CDS             6024..7358
                     /gene="murC"
                     /locus_tag="ACG8ZV_002086"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HFS4997374.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            7665..8150
                     /locus_tag="ACG8ZV_002087"
     CDS             7665..8150
                     /locus_tag="ACG8ZV_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MaoC/PaaZ C-terminal domain-containing protein"
                     /protein_id="HFS4997375.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            8143..8826
                     /locus_tag="ACG8ZV_002088"
     CDS             8143..8826
                     /locus_tag="ACG8ZV_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HFS4997376.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            8952..11597
                     /gene="polA"
                     /locus_tag="ACG8ZV_002089"
     CDS             8952..11597
                     /gene="polA"
                     /locus_tag="ACG8ZV_002089"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HFS4997377.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            11642..12478
                     /gene="mutM"
                     /locus_tag="ACG8ZV_002090"
     CDS             11642..12478
                     /gene="mutM"
                     /locus_tag="ACG8ZV_002090"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HFS4997378.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            12442..13071
                     /gene="coaE"
                     /locus_tag="ACG8ZV_002091"
     CDS             12442..13071
                     /gene="coaE"
                     /locus_tag="ACG8ZV_002091"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HFS4997379.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            13123..13455
                     /locus_tag="ACG8ZV_002092"
     CDS             13123..13455
                     /locus_tag="ACG8ZV_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HFS4997380.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            13767..14258
                     /gene="nrdR"
                     /locus_tag="ACG8ZV_002093"
     CDS             13767..14258
                     /gene="nrdR"
                     /locus_tag="ACG8ZV_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HFS4997381.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            14281..15654
                     /locus_tag="ACG8ZV_002094"
     CDS             14281..15654
                     /locus_tag="ACG8ZV_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HFS4997382.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            15654..16580
                     /gene="dnaI"
                     /locus_tag="ACG8ZV_002095"
     CDS             15654..16580
                     /gene="dnaI"
                     /locus_tag="ACG8ZV_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HFS4997383.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            16709..17149
                     /locus_tag="ACG8ZV_002096"
     CDS             16709..17149
                     /locus_tag="ACG8ZV_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HFS4997384.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            complement(17179..18138)
                     /locus_tag="ACG8ZV_002097"
     CDS             complement(17179..18138)
                     /locus_tag="ACG8ZV_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFS4997385.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRF
                     LKSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNG
                     VSETFIQSVASKRNHIPRKSLHYRTPMEVFLSYVTKDDLSNLI"
BASE COUNT         6131 a         3202 c         3966 g         4892 t
ORIGIN      
        1 atgtttacga atgaaataaa aatcatgctt tatgtggacg atgtagaaaa aaatgcaacg
       61 ttttggagag cagttggctt tgcggaaaaa gatcgtcaag aaatggatgg gacgcttata
      121 attgaagtag gagttgagga cagtcaaacc tcatttctgt tatatgatcg agcatttgtt
      181 gagtcccatt cacctggcac agctactagt gccccatctt tgatgtttta cagtaaagat
      241 atctttggac tatataaaaa aatgcagacg caatcagtca cattaggtga tatggtacag
      301 cttggagaag aatatgtctt taactttgct gatcccgatg gcaactactt tgcggttaca
      361 ggtaaataat agaaataaag actttgtttt tctgtgcgaa acaggaaagc gaagtctttt
      421 taattcaaat aataatatta tgtaaacaaa aaactttcca tgcgtaatta tacacaagca
      481 aataaatcgt caaatgcgaa cgccttcttt atactgttta ggaacgaaaa gaaggaagga
      541 agaaatacat ggattatcaa gtactgcttt attacaatta tacaaaaatc gaagaaccag
      601 aggaatttgc caaaaatcat ttagcctttt gcaaatcttt ggatcttaaa ggtcgtattc
      661 tagtagctga agaaggaata aatggtactg tgtctggaac cgttgaaaac acgactgcct
      721 atatgaaagc aatgaaagct gatcctcgat ttgctgatac gatgttcaag atcgatccaa
      781 gcgaaggaca tgcctttaag aagatgtttg taagataccg tccagagctt gtaagtttaa
      841 agctagaaga ggacattgat ccaaaccaag tgacaggtgc ctatctttca ccgcaagaat
      901 ttaaagaagc tattttagat gaacagacag tggtgattga tgcacggaat gattatgaat
      961 atgacttggg acattttcga ggggctgtac gcccagatat acgcagtttt cgagagcttc
     1021 cagactggat ccgcgagcac aaagaagaat ttatggaaaa acgggtagtg acctactgta
     1081 ctggtggcat tcgttgcgag aagttttctg gttggcttgt ccgtgaagga ttcaaagatg
     1141 tcggacagct gcatggcggt attgctactt atggtaagga tcctgaagtc caaggagaat
     1201 tatgggacgg caagatgtat gtgtttgatg aacggatcgc tgtcgatatc aaccaagtag
     1261 ataaacaaat cgtcggtcgc gactggtttg acggaacacc atgtgaacga tatatcaatt
     1321 gtagcaatcc tgagtgcaat cgtcagattc ttgcttccat tgaaaatgaa gaaaaacatt
     1381 taggagcatg tagcatagag tgtgcgaaac atccgcgcaa tcgctatgtt caagaccatg
     1441 gaatctctcc agaagaagca gaactgcggt ttacagcttt aattaaatag aaaacaatag
     1501 ttttgattgt cgaccatttc caatatgcgc tatactagcg ttgaggatgg tgatccacat
     1561 gaaatcattg atttatgcta ttggggatgt ccatggcaaa catgagcttt ttgaaaaact
     1621 tattcactat tatgatccaa agatccatca gcttgtttta ttaggggatc tcaatgatcg
     1681 aggtcctcgt acaaaagaat gttttttatt aggaaagcaa ttagtcgaag aaacaggagc
     1741 catttacctc cggggaaacc atgaagaata ttttttgcaa tttctgcaat caccggagga
     1801 ctggtatgcg ccttatatga gaaatggtgg aaaagaaacg tttgaaagcc tgattcaccc
     1861 aggggcatcg gaggaatact ccccaactga aatctcgatg atgatccaat cgagatattc
     1921 agaactgatt aaatttttag tccagcgccc cttgtattat gaatgggaaa attatctttt
     1981 tgtccatgcc ggtgtggatt tgacaaagaa agactggcgt aagacaagtc taagagactt
     2041 tatttggata agggaaccat ttcatgaagg gaaaaacaat acaggtaaga caattgtatt
     2101 tggacatacg attacaccaa tgctccatgg agatatgcag acaacagacc tctggattca
     2161 ggatcataaa atcggaatgg acggtggggc tgtattcgga gggtcattgc atggggttgt
     2221 ttttgacaag gaaggtattc ttcaagatat tgaatatcag aacaacgaag gaccttggca
     2281 tggaatctga ctaatggaaa gaatgaagga gctgtgactt tgttgcggct ctttttattt
     2341 ttatagagaa tattgtttct ttcagtagtt taacccagga taaaaagtat gatagaataa
     2401 agaagcaatt tttagcagaa aagaggcatt ttaatgacgg aaaatttgaa ccagacgatc
     2461 attcagcttg tacaaaaaga actttcagac tatcgtccta agcagttgac tactgtactt
     2521 aatttgttaa atgaaggaaa cactgttcct tttatcgcgc gttaccgaaa agaaatgact
     2581 ggaagtcttg atgaagtcca gattcgtgaa atcgaagagc ggtatgccta tcttgaaaac
     2641 ttagaaaaac gtaaaactga agtgattcgg ctaatcgatg aacaagggaa actgactccc
     2701 gagttagaag cagaaatcac ccaagccgtg aaaatgcaac aagtggaaga tttgtatcgt
     2761 ccatacaaac aaaaacgacg gacaaaagca acgattgcta aagaaaaagg acttgaacca
     2821 ctcgcgaagt ggctgatgca gcttacagat ggagaggtgc aatctgaagc agaaaaatat
     2881 attgacaaag aaaaagaagt ctcttctgcc gaagaagcgt tgcacggtgc tcatgagatt
     2941 attgctgaac aagtcagcga taatgcaaaa tttcggactt ggattcggtc ttatacgtat
     3001 aacaaaggta tgtatgtcag caatgtcaag gatgagcaag cagatgaaaa aggcgtatat
     3061 gaaatgtatt atgactttgc agaacccgtc cataaaatgg tttctcatcg aatattagct
     3121 actaatcgtg gagaaaaaga agatattctg aaagtattct ttcaagtaga tgaagcagca
     3181 attttagctt acttggatcg ccaaatagtc aaaaatcctg cctctccttc ttcttcattc
     3241 gtcagagaag cctatcagga tagttataaa cgctttattc agccagcaat cgagcgagaa
     3301 ctgcgcaatg aattgactga aaaggcagat gagcaagcaa tcgctatttt cggcgaaaac
     3361 ctccgtaatc ttttgttgca accgccacta aaaggtaaag ttgtcctggg atttgatccg
     3421 gcttatcgta ctggatgtaa actagcagtc gtagatgcga cagggaaagt tttagcaatc
     3481 gaagttattt atcctcataa acctgcagcg caagcaaaaa gagaagctgc tggaccagct
     3541 tttatccaat taattaataa atatcaagta gatatggtag ctatcggaaa tggtacagcc
     3601 agtcgggaat ctgaactttt tgtggctgag cagttgaaat ccgccgacca taaaacctat
     3661 tacgctatcg tcaacgaagc aggcgcttct gtttactccg ctagcgaaat tgcacgaaaa
     3721 gaatttccgc atctacaagt tgaagaaaga agtgctgttt ctattgcccg tcgcctgcaa
     3781 gatcctttag ctgaattagt caaaatcgat cctaaagctg tcggagtagg ccagtaccaa
     3841 catgacgttt ctcaaaaacg tttggctgaa caattggatt ttgttgtgga aacagcggtt
     3901 aaccaagtag gtgtggatgt gaatacagca agcccgcagc tcttgcagca tatatcagga
     3961 ttgaataaaa caactgccca aaacattgtc atttatcgtg aagaaaacgg agaattcacc
     4021 gcacgaactc aattgaaaaa agtgccacgc ttaggaccaa aagcatatga acaagcaatc
     4081 ggattcttgc gagtccctgg tgggaaaaac attttggaca acacaggtat ccatcccgaa
     4141 agttattcta ttgcaaaaga aatattaact tcagtccaac tttcagaaaa agagcttggt
     4201 acagaagaag cagtagaaaa attgacacga ttatccgtag agaaactggc tgaaagccta
     4261 tcagtcggag aagaaacgtt agccgatatt ttagctgggc tgacacaacc tggacgagat
     4321 atgcgtgatg agatgccagc gcccttatta cgtacagatg tattgagtat ggaagacttg
     4381 aaaccaggga tggaattgac tggaacggtc cgtaatgtca ttgacttcgg cgcatttgtt
     4441 gatatcggtg tgaagcaaga cggacttgtc catatatcga aactcagcaa aaaattcgtc
     4501 aagcatccta cagatgtcgt gtcagtagga gatatcgtaa cagtttggat agaacaagtc
     4561 gatacgaaaa aaggcagaat cagtttgacg atgctttccc cttatgaaga gtaacaatga
     4621 ggagtaacaa aaattgacac aagaagaact gcagcagtta gtagaagaga tatcattaaa
     4681 aagcttccag cttcctttca agcaccaagc aatgttcaat ccacgcttac gtacaactgg
     4741 cgggcgctat catttaaacg atcatcattt agattttaat gcgaagctat ttgaagagtc
     4801 agacgaagag acgattgcag gaatcatcaa acatgaactt tgccattatc atcttcatct
     4861 agctggaaga gggtatcagc ataaagatat ggatttcaag tatcttttga aaaaaacagg
     4921 agggttgcgc tatgcaccag ccttgacgaa gaaacagata aagatggagt attatcgatg
     4981 ccaagattgt tctgccacga tctgccgcaa gagaagaatc gatgtacgca aatatcgttg
     5041 tggaagatgt catggagaaa tcaaatggat tgagacaaaa agagaagact ttaatgaagc
     5101 acaaaaaatc agatgaaagg atagaaggcc tttggaaaaa agtgagcaga ggaatctaaa
     5161 agactggaat cagctattaa attttttagc cgcacctgaa gagggaaatt ttgaggaact
     5221 gacggcacct acacttattt tagctggaaa ctgtcttcct atcttagctg ataaagcagc
     5281 acaaatgtat ttaaatggcc aagtagatca attgtttttg gtcggagggg tggggcatgc
     5341 gactagaatc ctttatgaga attttgaaaa gcaaggattt cattttgaag atggcatgag
     5401 tgaaagtgaa atctgtcgtc agtatctaaa agaagtctat gatttgcccg ataaggcttt
     5461 tctgatagaa tcgaagtcta caaattctgg agagaacgcc actttttcac tggagattct
     5521 tcattcctta ggagctgtac cagaaaaaat cttattgatg aatgatccga cactgcaacg
     5581 caggactcga gcaacttttg agaaagtatg gcaaaatgaa caaactattt tcgcgaatgc
     5641 tgtgccattt gtgccggaaa tccttcactt ttctgaagag atcatcttta cagcaaaaga
     5701 actgaatcat caatggccta aggaatattt ccatgcgcta gtattaggag aaatggaacg
     5761 tctccatgac gatgagaacg gctatggtcc gaaaggaaaa gattttattc ctcacattga
     5821 tatatcagag gaagtttggt cttcttacac cagaattaaa gagtcaataa aaacggattt
     5881 ttctcgtact tgaccatttt agcaagcgaa tcctcctttc caaataaatt tggttgaaat
     5941 tttcaatcgt ttataagata atgaggagcg tgttgaatgt aatagctaaa agaatggacg
     6001 ctagataaga gaagaggatt caaatggaaa atcaaaataa attgtatcat tttgttggta
     6061 tcaaaggttc aggaatgagc tccttggctc ttgttttaca tgaacaaggt ctaaatgtcc
     6121 aaggatcaga cattgaaaaa tatttcttta cacaaagaga tttagaaaaa gcaaatatca
     6181 cgattctgcc atttaacgca gataatgtaa aaccagggat gacgatcatt gcaggaaatg
     6241 catttcctga ttcacatgaa gaaatccagc gagcaaaaga attaggtttg gaagtgattc
     6301 gctatcacga ctttattggt cattttatcc aaaattatac gagtatcgct gtaacaggct
     6361 ctcacggaaa aacaagtacg actggactgc tctctcatgt attgagtggt gtccgtccaa
     6421 caagttatct aattggagat ggaacaggac atggtgatcc gcaagcggaa ttcttttcat
     6481 ttgaggcctg tgaatatcgc cgtcatttcc ttgcctattc accagactat gcaatcatga
     6541 ccaatatcga ttttgatcat ccggattatt atacaagtat cgacgatgta tttacagctt
     6601 tccaaacaat ggctggacaa gtgaaaaaag ctatttttgc gtatggtgac gatgcttatt
     6661 tacgcaaatt aaaagcaaat gtgccgattt attattatgg tgtcacagaa aacgatgata
     6721 tccaagcacg aaacatcgaa cgcacaactt ctggttctgc ttttgatgtc tatcatgggg
     6781 atgaatttgt tgggcacttc actgtaccag cattcggtaa acacaatatc ttaaatgctt
     6841 taggtgttat tgcagtagct tatttcgaaa aactggatct gaaagaagtt gcagaagaaa
     6901 tgctgacttt cccaggagta aaacgtcgat tcagtgaaaa gatcgtagca gacatgaccg
     6961 tagtcgatga ttatgcgcat caccctgcag agatcaaagc aacgattgat ggcgcacgcc
     7021 aaaaatatcc agataaagaa ataattgcag ttttccaacc ccatacgttt acgcgtacga
     7081 ttgcattgat ggatgaattt gcagaagcac ttgatttagc tgataaagtt tacttatgcg
     7141 atatttttgg ttcggctcgg gaagaacaag gaaacgttaa gattgaagac cttggagcga
     7201 aaatcaaaaa aggtggagaa gtcatcaaag aaaataatgt atctccattg ttagattatc
     7261 atgatgcagt agtaatcttc atgggtgctg gagatgttca aaaatttgaa caagcgtatg
     7321 aaaaactttt aagcagcacg acgaaaaatg tactgtaata caattactgc agtgtcctta
     7381 taaaaataga aagaggggga gtggcaaaaa tcttgccaag cccccttttt tgcaacttat
     7441 gataaacggt gttcaaaagc ttgcatctgc ggtaataagc ccaatcaaat caaaaacatg
     7501 agaagctgtt ttttcttggc tgttcttatt atttgatgca ggacagcttt ttcacgacct
     7561 ctgtaaacta taggaatctg ttaaatcaag ggagcagaac ttgcctttta cgctactttt
     7621 ggtacaataa tgtatgatta aaaataaact ggagggtttc tatcttgaac ataggtaagc
     7681 cgagaaaact aggaaaaaca ataaatgaaa tcgaggaagg cgactcgtta tccttaacag
     7741 aatctattga agataaccag cttttgctgt atttgggatt gacgaatgat gcaaatcctt
     7801 tgtatatcca acatgacttt gcacaaaaaa cagaatatca acagccaatc gttccatcag
     7861 tgatgctgat ggggatcatc acaagtgcaa tttcaaagca tcttcctgga ccaggatcac
     7921 atgttgtcaa tttttctgtc aattttattg aaccggtttt ccattatgaa acactgactt
     7981 ttcagtttga ggtcataaaa gtagataaga tgaaggatgt ggtgacgatt tctgtagaag
     8041 cggagaatac gaacgaagat cgtgtgttgg atgctgtcgt tatggtccaa ccgccacaag
     8101 ttcctgaatt ggaaatagca atcgaaagtg aaggtgaatt gaatgaataa tccaagtaca
     8161 tcaatgtcag gtatcaatcg tttttatgca aaagtttatg gatttttagg tatgggactt
     8221 gcccttagtg cagtcacttc ttacttggct ctttgggtat ttcctttgca attagcaact
     8281 tttatcaata attttccact aggctttgtg ggtctgtgga tcgttgaact gattttagta
     8341 atggttctag gcgtaaaagc acaaaagaat ccgagcttag caatcggtgg atttattgcc
     8401 tactctcttt tgaatggcat aacattagcg gttactcttg catactacga tattggaaca
     8461 gtaacgcaag ctttcttgac agctactttg atgttcatgg ggatgtctgt tgtcggagta
     8521 acaacaaaaa gagatcttag cggggttgga agagcaggac aggcagcttt aatcggagtg
     8581 atcattgcac tagtcttgaa catcttcatt ttgagaagta gcgtagttga gctgttcatc
     8641 tccctactgt tagtcgtcat ctttgcaggg attacagctt atgataacca aagcatccgt
     8701 aatatctatg tccagacaaa cggaacagca catagtggaa ttgctgtatt catggcattg
     8761 aagctgtatt tggactttat caacttgttc ttggcgtttc tgagaatctt tggacggaac
     8821 aactaaaaaa gaaaaaaatt catcagttgg ggctataccg aattatttgg tatggtcccg
     8881 ctttttcttt tcgcattccg caggattctt tgttagaatg aataagaact ttacagtaag
     8941 gagttaagaa gatgacaaaa aataaattat tactcgttga tgggaacagt gtggcttttc
     9001 gcgcattctt tgcgcttcac aattctcttg aacgtttcaa aaatagaaac ggtcttcata
     9061 caaatgcaat ctatgcattc aatacgatgt ttgaaaatgt tatgcaaaaa gagcaaccga
     9121 ctcatgttct ggttgcgttc gatgcaggaa aaacgacttt tcggacagaa atgtatgcgg
     9181 agtacaaagg tggaagatcc aaaacacctg gcgaattcaa agaacaaatg ccatatatac
     9241 gtgatttgtt gacaggacta ggggtacagt attacgaatt gcccaattat gaagcagatg
     9301 atattatcgg tactttggca gaaaaagtag acaaagatca atttgatgtc gtcgtgcttt
     9361 caggtgatcg ggatttgact caattagcta gtaaagaagt aaaagtggat atcactgtaa
     9421 aaggtgtcag cgatatcgaa agctatacac cagaacatgt agcggaaaaa tatgatgggt
     9481 tgacgccaaa acagattatt gacatgaagg gactagccgg agatgcctct gacaatatcc
     9541 ccggtgtgac taaaatcggt gaaaaaacag ctatcaagct attgaaacaa tatggctcag
     9601 tcgaaggaat ttatgaacat atcgatgaaa tgaagcaaag caaaatgaaa gaaaatctga
     9661 taaatgacaa agagcaggct ttcttatcga aaaaattggc gaccatcaat acttcagcgc
     9721 ctgtggatgt ctctatcgac tcattgaagt atgaagggaa aaatctcgat aaactcgttc
     9781 cgttttataa agaaatggat ttcaatcagt tcctttctaa attgaatatc gtagaagaag
     9841 aagtaaaaat ggatgatatt ttgtttgaag tcgttcatga attcaaagag gaaatgttta
     9901 ctacggatat ggcgttgtac gtggaaatga tgggcgacaa ttatcataca gaggaaatcg
     9961 tcggagtagc gtgggggaca gaaaagaaaa tttatgtcac gaacgatcta tctgtattcg
    10021 aaaaccgagc gttccattct tggatcactg atccgactcg gctgaaaaaa gtatatgatg
    10081 cgaaacgaac ttatgttgct ttaaaccgct atactggaaa aacgaaagga atcgattttg
    10141 atgtcttgct aggtgcatac cttctcgata cgaatgaaaa aagcacagat atcgaaggaa
    10201 tagctgctca ttacggatac aacgatatcc aatcagatga agctgtatac ggcaaagggg
    10261 cgaaaaaagg tttaccagaa gaagaggaac tcttttttgc tcatttagcg cgaaaagtag
    10321 ctgcaatcaa tgcgttgaca ccaaaattga gccaagaact ggcagaaaaa aaccaagaag
    10381 atcttttccg gaaaatggaa ctgccattgt ctatcatttt ggcagagatg gaaataagcg
    10441 ggatcaaagt agatgcgact cgcttacaag aaatgaaggg cgagttctct gctcgcttaa
    10501 gagagatcga acaaaaaatc tacgaagaag ccggcgaaga attcaatttg aattcaccaa
    10561 agcaattagg agtgatctta tttgaaaaaa tgggattacc cgttatcaaa aaaacaaaaa
    10621 ctggatattc cacagccgta gatgtactgg aacagcttcg tgaacaagca ccaatcgtag
    10681 aggatatcct cacctatcgt caaattgcaa aaattcaatc tacctatgtc gagggactgc
    10741 tgaaagtgat ccaatcagat ggaaaagtgc atacccgtta tgtccagaca ttgacccaaa
    10801 caggacgatt aagctctgtt gatcctaatt tgcagaacat cccgattcga ttagatgaag
    10861 ggagaaagat acgtcaggca tttgttccta gagaaaaaga ctggctgatt tattcttctg
    10921 actattcaca aatcgagtta cgcgtacttg cgcatatctc aaatgatgaa catttgaaag
    10981 ctgccttcct agaaggtcaa gatatccatg ccagcacagc gatgcgtgta tttggaatcg
    11041 aaaaggcaga ggatgtcaca ccaaatatgc gtaggcaggc aaaagcagtg aattttggta
    11101 tcgtgtatgg catctctgat tacggacttt cacaaaatct aggaatcagc cgaaaagcag
    11161 cacagcaata catcgatacg tactttgaaa aatacccagg tgtcaaagaa tatatggaaa
    11221 gaatcgtacg cgaagcaaaa gaccaaggct acgtcgaaac gctgtatcac cgccgtcgat
    11281 atctgccaga catcaattca agaaattaca atatccgttc ttttgcggaa cgaacagcta
    11341 tcaatacacc aatccaagga agtgctgctg atattttgaa aatcgcgatg atcgaattgg
    11401 ataaacgatt aaaagaaaca ggtcttcaag ctacgatgct gttacaagtt catgatgaac
    11461 ttgtcttcga ggtaccggaa aaagaacttg aatcattaga taaattggtg aaggaagtta
    11521 tggaacaagc tgtttctctt catgtaccac tgatcactga cagcagttgg ggaaaaacgt
    11581 ggtacgaagc aaaataaaca ttgtttaaga cagagcaata taatgaaggt gaaaagaaaa
    11641 aatgccagaa ttaccagaag tagaaaccgt tcgtaaagga ttggaacggt tagtagtagg
    11701 aaaaacgatt caaaaagttc aggtcttgtg gcccaagatc atcgagcaac cagagacacc
    11761 catctttgag gcttctcttg ttggcgaaac catccaatcc attggacgta gagggaagtt
    11821 tttaattttt catctcgatc attgtgaact gatctcacac ttgcgaatgg aaggaaaata
    11881 tcaatttacg aaagaaaata caccaatcga taaacatacg catgtacttt tcttttttga
    11941 ggatggaagc caacttcgct acaacgatgt acgaaaattt ggtcgtatga caatcgtcga
    12001 aaaaggagca agtgcaactt accgaggaat catgaaattg ggacctgagc ctttgccaga
    12061 tagcttctta ttagcagatt tcgcaaatgg actgaaaaag tcccacaaag caatcaagcc
    12121 attgctgcta gaccaacgtc tagtgactgg tctaggtaat atttatgtag atgaagcatt
    12181 atgggaagcg aagatccatc cagaacaacc ggcgaacaca ctgcgcccca aagaggtaga
    12241 acaattacgt ctatcgatca ttgatgtttt ggatcgtgca atagaagccg gaggtaccac
    12301 gattcgcagt tatttgaatg cattaggaga atcaggcgga tttcaagtag cactgcatgt
    12361 ctatcagcaa actggcaaac catgtatacg ttgtggaacg ccgatcgtga aaacaaaagt
    12421 ggcacaaagg gggacgcact attgtccgaa ttgtcaaagg ctaaaaatcg caaagtagga
    12481 tttgttttag gtttgacggg tggaatagct accggtaaaa gtacggcagc caaagtcttt
    12541 cagtctcatg gatttccttt gatcgatggc gatgtgattg ccagagaaac tgttgagcct
    12601 ggaacgcttg ctctgaggaa aattgtatca gtgtttggcc aagaggtatt gcagcctgat
    12661 gggcaactag atcgagggaa acttgggatg attgtttttc catcaaagga aaaacggcaa
    12721 aaacttgatc agctattaga tccgtttatc cgaaaagcga taaaagatca aatcgcctct
    12781 ctaagttcca atcatccttt agtaattgta gatatcccat tgctctacga aggtcattat
    12841 gaccactata tggatgcagt agctgtcgtt tatactacgc cagaaactca gcttcagcgt
    12901 ttgatgaaac gtaatcaact gacgctagaa caagcgcagc agagaattag tagtcaactt
    12961 ccaatcgaag aaaaaaagca gcgtgcggat attttgttcg acaacaatgg aacaaaagaa
    13021 aaacttgtgg gacaaatcga aaattggctt tttgctaatc gctttctttg agtatctgtg
    13081 tcaattttgc tatcctgagt atatagaaag tgagggatag cgatgggatc attaaaaaat
    13141 caaaaggata aagtcgtagg taacgcaaaa gaaaaaatcg gcgagatgct caataaagaa
    13201 aatctaatcg atgaaggtcg tacgcaatca gaaacagcag aagaaaaaga aaagcagtac
    13261 caagcaagaa tcgatgaaat agaagaccag caggcagaag aagaagcgaa gcggcaagat
    13321 ttgactcaag aacgaaaaaa tccgacacct gatcgtagta aaacaccgct cccagaaagt
    13381 gaccacattc ccgatgagca aaaaatcgag gaacagcgaa tgaaacacta tacaggaatc
    13441 gaagagaagt tataaaatag taaaaaatcg agatgtgact tgaagcagat gagaaggtgt
    13501 tcatctgctt caagtttttt gtgctagatg actaaatcag cttttgtgta agttatttct
    13561 cagtaatcaa ggtgatcagt attggaaaat tgaaatttag taaggacagg ggacacaatt
    13621 acgcatgaaa gtagaaaaaa ttgttcttat atccgtgttt tttgggtagg acagtcgcgt
    13681 ttgtgatttg tttcgtgtta taatacaact agttgtaaag aaagacacat cctttatata
    13741 aaatgcgatg caagaggtga gacaaaatga gatgtcccag atgtcaacat aataattcac
    13801 gagtaatcga cagccgtcaa gcagatgatg gacgtgcgat ccgtcgccgt cgcgaatgtg
    13861 agaattgttc gttccgattc actacatttg aacgaattga agctgctccg ttattagtaa
    13921 tcaagaaaaa cggggaacgc gaagagttca atcgcgataa aattttaaga ggactcatcc
    13981 gttcagcaga aaaaagacct gtagctatgg aacaaatgga acaaatcgtc aaccatgtcg
    14041 aaaaccgcgt acgcagtctc ggagaaaacg aagtatcgac gaatctaatt ggtgaatatg
    14101 tgatggaaga tttagttgat ttagacgaaa tcgcttatat tcgttttgca agtgtttatc
    14161 gccagttcaa agatatgtct gttttcttaa aagagttgca agatatcgtg gataaagcaa
    14221 aagaaaataa taaagagaat aataaagaaa acaattaaga aacaaaaagg aggcatttcc
    14281 ttggaaaatg cttggaaaga gcttcaacca aaaaatattt accaaggaag aaaagcggct
    14341 ccgctgagag aagacagcaa gaacgccttg ctgtatcttt atcagccact aatcggcgga
    14401 gaagccttga gtatctattt caccctgtta tcagaaatct ctcaagaatc tggcaaaggt
    14461 cctgaaggga tgcatgcaga tctgcttagt agtctaggct gcggtatccc gcaattttat
    14521 gatgcaagaa aaaagctaga aggaatcggc ttactggatg tttattttaa agaagatagt
    14581 gatctgggac ctcgttttat ttatgagctg ttagaaccac tcattcctaa agcatttttc
    14641 aaagactctg ttctggcttt tcttcttctg gaaaaagttg gtgaacgacg attccagaag
    14701 cttacccaat tctttgaacc taaaaggcat acagcagagg gatatcaaaa aatcacaaaa
    14761 aaatttttag atgtttatcg cttcaatgaa gcagtgtacg ctgctaatca agaaaacatc
    14821 gaatcgctga ataaatcttt tgaagaatct gaatcagtag cattacttga agcagattcg
    14881 acattcgatt ggcagttttt gaatgattgg ctggcaaaaa aacatattgc aagtcttgat
    14941 gatccaatca tcaaacaagt cgacatgtat catcagcttt acggtttcga tgaattgaca
    15001 cttggcgaac tgatcagtca atcttatgac tttagtgaac aaaaagtatc tgaaaaagaa
    15061 ctgcaaaaag ccattttggc aatgcagaga cgtccggtga agcaaacaaa agaaacagtt
    15121 gcggtttctg aaaacagtaa tgaaccctcg tcaaacgaac atttgacaaa cgcagcgctt
    15181 cagctgataa aagaagcaca gagcattcca ccgatgaaat atctggaagc aatcaagtca
    15241 gaaaaaggcg gatatgtttc taaacaagaa aactggttac tgcaagatct tgtttctcaa
    15301 tcaggtcttt ccagtagcgt gatcaatgtt ttgctgaatt atgtactagt gatcaagaat
    15361 aatgctagct taaatgccag ttatgtaaat acagtggcaa atgaatgggc acaaaagaaa
    15421 atcgccacag cagaagaagc gatccagcac attcggcaaa taagtaatca agcaaaacaa
    15481 tcaaaacaaa agaagcaaac aaattatcaa actggcaagc gaaatgttcg acgggaaaag
    15541 cttcctgatt gggtcaacca gccaaaagat gaaaaacaga tcagcagcga gaaaaaagca
    15601 gagattgacc gccgttttaa agaatacctg gcaaaaaagg agggtgatat ctagtggaag
    15661 acgtaggcaa agaattgaag aggatcatca gcaaacgcaa ttatcaagaa aagtatgctg
    15721 aaatgatcgc tgaagtctta aatgatgcgg atgttcaagc ttttctaagc gcacaccaag
    15781 aagaattgac acaagcggat attgaaaaaa gttacgctaa attgtatgaa ttcgtgcaag
    15841 aaaagcgtaa atatcaaaaa aacgatccaa cgatgatcgc tcccggctat gagccgaagc
    15901 tgacgttgaa ttttcattat gtggatgtca cttatgtacc aacggaagca ttgttagcac
    15961 ggcaaagaca agaagaaatc agaagccgag taaaagcaat ggatatgcca aaagatattc
    16021 aatcggcttc ttttgaaaac tttgaacgta cagatggacg aggatatgcg agcttagaag
    16081 ccctagattt tgtagagaaa tatactgctg atccaaaagg gtatcataaa ggactgtatc
    16141 tagtaggaag ttttggtatt ggaaaaacat atttattagg agcaacagcg agagaattag
    16201 cgattgctgg attcaccacg acgctagtcc attttccgac atttgccgtt gagatgaaac
    16261 aggcaatcgg aaaagatcaa gtggcagaaa agttagatgc agtgaaacgt tcacctattt
    16321 tgatgatcga tgacattggt gcagatgcga tgagtagttg gatacgagac gaagtattcg
    16381 gtgttatcct tcaatatcgg atgcaggaac agttaccaac cttcttctca tcgaatttta
    16441 caatggatga attggaacag catttgtccg tcactcaacg tggagatgaa gagccgctaa
    16501 aagcgaaacg gataatggaa cgcatacgtt atttgacaaa agaaatcgaa atgactggtc
    16561 gcaaccgacg caatggttga acagttgaca agtccaactg acatttgacc tagtagtaaa
    16621 agcaggtcag cgaatcatta tatggacaga aatgaccgga gacaatcacc gcaacaagta
    16681 atgcagaaac ttaaacggag gattttttat gagggctatt ttttctagta tatctgtagt
    16741 tggtctattt tttcttttag caggctgcgg tagcgcagat agcaacacag gttctgttga
    16801 ttcgattgat gcgggtcaaa cagtaaaaac aagcagtacg aaaacggaga gacaaagcat
    16861 atttgtcgga acgattgaaa gtatcactca agtagaagca gaagaagaaa cgcttcagtt
    16921 gaaactcgtc gatgtcatgg ccaaagaaga tccagcgaat atgggaacgt cattcagcaa
    16981 tgacggagtg atcttaaatg ctactgctga aaaaataagc gtggacataa atgaattgaa
    17041 aatcggtgac aaagtccaat ttacattagt tgagatgccg atcatgacga tgtctatccc
    17101 accgcaagtt cctggagatt cgattattga tgtttcattg aacaaataac caataacatt
    17161 ttttcaaaat ttcgtttgtc aaattaagtt agacaaatca tcttttgtga cgtaactcaa
    17221 aaatacttcc attggtgtcc gatagtgtaa tgattttcta ggaatatgat ttcgtttcga
    17281 tgccaccgat tggataaagg tttcagatac accattaaaa tccatagctt tatacaaacc
    17341 atctttacgt aataagccat ttgaatgttc attcaatcct cgttgagaag gtgttcctgg
    17401 atccgcaaaa taaattgaaa tatcgttggt attactaatc tttttccaat ttgagaattc
    17461 ttttccacaa tcaaatgtga tggatttaaa taagtttttt gggacacaac gaaaccattg
    17521 attcagccta ttttcaatgt ctttagcctg tctgccttcg ggtttcaagg taatgatgac
    17581 tttagatagc cgttcaacta atgtgatgac cgcgctttta tgttttccac ccacgatagt
    17641 gtcaccttcc aggtgaccaa attcatgatc aaactgggta tagtctgtct ttctgtctcg
    17701 gattgaccgg cgaaaccctt gttttcctct tttttcttta tgaccgtttg gttttctttt
    17761 tcccttcatt ggtaaatcgt gagtgtcaaa ggttttatct ttaaacattc gatacagtgt
    17821 gcgtaccgaa caagcaatag gaaactctgc tcgaccaata aggacatcag gagcccaccc
    17881 ttgaacaacc tttttttgaa tgtattcctg ttgctcatca ggtaaaacaa tcggatgtct
    17941 tccgcagtta cgtttgtttt tcttatattg tttatagtag ctcattgcgc ttccaccaga
    18001 tttaagaaaa cgatagacct tataaatagt ttgtcgagaa cgttgtaaca gattggctac
    18061 ttttgaaaca ggttgtgatt gattgaaata agcttctatc attacgagtt cagttggtgt
    18121 aagatggtta taggtcattt gtactcactc cttataattc tttcgtcgga actattttga
    18181 gtgtagcaca a
//
LOCUS       DAZULR010000048        18125 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.049, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000048 DAZULR010000000
VERSION     DAZULR010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18125)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18125)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18125
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.049"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(26..724)
                     /locus_tag="ACG8ZV_002098"
     CDS             complement(26..724)
                     /locus_tag="ACG8ZV_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HFS4997386.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(717..2069)
                     /locus_tag="ACG8ZV_002099"
     CDS             complement(717..2069)
                     /locus_tag="ACG8ZV_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurT ligase domain-containing protein"
                     /protein_id="HFS4997387.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(2292..3692)
                     /locus_tag="ACG8ZV_002100"
     CDS             complement(2292..3692)
                     /locus_tag="ACG8ZV_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HFS4997388.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            3853..4590
                     /locus_tag="ACG8ZV_002101"
     CDS             3853..4590
                     /locus_tag="ACG8ZV_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HFS4997389.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            4715..5194
                     /locus_tag="ACG8ZV_002102"
     CDS             4715..5194
                     /locus_tag="ACG8ZV_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HFS4997390.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            5191..5958
                     /locus_tag="ACG8ZV_002103"
     CDS             5191..5958
                     /locus_tag="ACG8ZV_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6681 family protein"
                     /protein_id="HFS4997391.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            6188..6757
                     /gene="lepB"
                     /locus_tag="ACG8ZV_002104"
     CDS             6188..6757
                     /gene="lepB"
                     /locus_tag="ACG8ZV_002104"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFS4997392.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(6861..7463)
                     /locus_tag="ACG8ZV_002105"
     CDS             complement(6861..7463)
                     /locus_tag="ACG8ZV_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HFS4997393.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            7569..7799
                     /locus_tag="ACG8ZV_002106"
     CDS             7569..7799
                     /locus_tag="ACG8ZV_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997394.1"
                     /translation="MPISFVKDREEKGKCVREILLDLPEWFGLPESTEKYIEESSKLP
                     LWCEKRKEEYLGFITLSQTSEDTAEIYSIVWE"
     gene            7790..8038
                     /locus_tag="ACG8ZV_002107"
     CDS             7790..8038
                     /locus_tag="ACG8ZV_002107"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF025054.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4997395.1"
                     /translation="MGIKKDYHHQGLGTKLFKEAEGYAAKHYKYLQVKTVDEGHYSIY
                     DQTICFYESLGFSRLEVFPNLWDEWNPCLVLVKKLEQK"
     gene            8144..8728
                     /locus_tag="ACG8ZV_002108"
     CDS             8144..8728
                     /locus_tag="ACG8ZV_002108"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HFS4997396.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            8731..9804
                     /gene="prfA"
                     /locus_tag="ACG8ZV_002109"
     CDS             8731..9804
                     /gene="prfA"
                     /locus_tag="ACG8ZV_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HFS4997397.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            9797..10636
                     /gene="prmC"
                     /locus_tag="ACG8ZV_002110"
     CDS             9797..10636
                     /gene="prmC"
                     /locus_tag="ACG8ZV_002110"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HFS4997398.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            10629..10808
                     /locus_tag="ACG8ZV_002111"
     CDS             10629..10808
                     /locus_tag="ACG8ZV_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997399.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            10830..11855
                     /locus_tag="ACG8ZV_002112"
     CDS             10830..11855
                     /locus_tag="ACG8ZV_002112"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HFS4997400.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            12030..13274
                     /gene="glyA"
                     /locus_tag="ACG8ZV_002113"
     CDS             12030..13274
                     /gene="glyA"
                     /locus_tag="ACG8ZV_002113"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HFS4997401.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            13427..14374
                     /locus_tag="ACG8ZV_002114"
     CDS             13427..14374
                     /locus_tag="ACG8ZV_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase fold domain-containing
                     protein"
                     /protein_id="HFS4997402.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            14508..15137
                     /gene="upp"
                     /locus_tag="ACG8ZV_002115"
     CDS             14508..15137
                     /gene="upp"
                     /locus_tag="ACG8ZV_002115"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HFS4997403.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(15276..15518)
                     /locus_tag="ACG8ZV_002116"
     CDS             complement(15276..15518)
                     /locus_tag="ACG8ZV_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997404.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            15639..15711
                     /locus_tag="ACG8ZV_002117"
     tRNA            15639..15711
                     /locus_tag="ACG8ZV_002117"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:15672..15674,aa:Thr,seq:cgt)
     gene            complement(15830..16468)
                     /locus_tag="ACG8ZV_002118"
     CDS             complement(15830..16468)
                     /locus_tag="ACG8ZV_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HFS4997405.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(16591..17223)
                     /locus_tag="ACG8ZV_002119"
     CDS             complement(16591..17223)
                     /locus_tag="ACG8ZV_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HFS4997406.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            17574..17873
                     /locus_tag="ACG8ZV_002120"
     CDS             17574..17873
                     /locus_tag="ACG8ZV_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFS4997407.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
BASE COUNT         6214 a         3162 c         3571 g         5178 t
ORIGIN      
        1 tgtcacattc ccctttttcg aataactagg ctgtttgtcc ttcaagatag ggcagatcca
       61 attctttacc gtaacgttgt tctaaagcta ggcggatcaa acgagctgcc aggttctcat
      121 ttcttgcaag gataggtcca tggaaataag aaccgaagac atttcggtaa atgacacctt
      181 cagattggtc ttcaccatta tttccttgac cttgtaccac tttccccaaa ggtcgttcac
      241 cttcacctaa gaaagtccga ccattgtggt tttcaaatcc ataataagtt tcattgaatt
      301 cttcgttatg gataacgata tcaccgataa accggttatt ttcctgactt aacgtgtagt
      361 gatccagtgc actgattcct tggatctttt ctccattagc tcccatgtag tagtgaccta
      421 gcaattggta gccaccacaa atggctaaca tgacgccatc attttcgata tagttgatca
      481 aagaatcttt ctttttctgg atgtcttttg aaatgattaa ttgctcaaag tcttgaccac
      541 cgccaaagaa aaccaagtca tatttatcag catcaaaagg ttcatgtata ctaacgatct
      601 ccgtatggca agaaaccccc attttttctg ctatatattt caacatcaaa aggtttccgt
      661 tatcaccata tgtgttcatc aaatttccat aaaggtgggc gatattgagt tcataattag
      721 ccacggttca ttcctccttt gataaatcct tgagcagcta gttctttacg aagctgcaat
      781 acagcagtgt aagtagctaa aatatagaca tgctcagttg gcaattcttt gattttttcg
      841 attacttctg gtaattcttt tgtttctgtc aatttatttt ctggaatccc ggcaactttt
      901 agacgtaaag tcatatctgt atgacggtct cctccagaaa taacagctgg gatatccata
      961 tcggcaaagt tttcaaaatt accatcccaa atccagctga catcgattcc gtctgcgtaa
     1021 ttggcattta ataaagccac taaagaaaat ggataaggag ctagaccaat catatcgatt
     1081 acttgattga tacctacagg atttttgaca agtactaatg tacatttttt cccattgata
     1141 ttgatgactt cttgtcggcc gaatactttc tcgtcatatc ctaaaccttg tttgatttta
     1201 tcaggatcga cattgaagta ctctgccact gcagtagctg ctaaagcatt gtagacatta
     1261 tacataccgc caacttcgat tccgtattca tgaccatcga tcacgaaatc tgctgacaca
     1321 ttgtccatcc gtaccatatc agttaatcga taatccaatt caggacgttt gaagtcacaa
     1381 tttggacagt aatatttccc taagtttgca taagtgatca ttttataatg caagatgtga
     1441 tgacaatttg gacataagac accgtctgta ttgtaatgag ccatttgttc acgatcttct
     1501 tcatggtcaa agccataata ttttctagga ttgactgttt cgatagaatt gaagattggt
     1561 gaatcaccgt tactgataat cgttgcattt ggtgactttg cggcaccgtc tacaatcatt
     1621 ttataggtcg tatagatttc tccataccga tccatttgat cacggaaaat atttgtaaat
     1681 aagaacagtt ctggtttcat atattctgtg actttgctca aacttgcttc atctatttct
     1741 aggacagcaa actttttctg tccttttttt ggttttgcct gcaagaaagt cgatacaatt
     1801 ccctgtacca tattcgcacc agtagggttg gttagaactt catcgaattg ctggcgcaaa
     1861 atattgactg ttaaagcggt agtcaatgtt ttaccgtttg ttccggtgac aacgacgact
     1921 tggtagtctt ttgccaaact atctagtata tgtggatcga ctttcagcgc tagtttacct
     1981 ggtaaacttg atccgccttt aaaaaaagtt tttaatgccc attgcgacgt ttttccaact
     2041 gcaatcgcaa aatgactgcg tattcccatt atgtaacctc caaaaacgat ttgctgacga
     2101 ataaattcaa ctaatcatac catatgttga aaaaaaggtt aaattgcttt tcttattctt
     2161 aagaaaaggt tacggctgaa agtgcatgaa atcggacaaa atcgcatgat ttaacaaaaa
     2221 aacagcttga aacaaaatga ttgtttcaag ctgctgtgat tttattattc cctcttacct
     2281 atattcccat tttaaccgat aataattttc tcgcttggat attcatagcc tagatctcgt
     2341 gtttcttttg gcacgaataa catcaatgta tatagcattc cgatccgccc aataaacatc
     2401 agtgtagcaa tcgtgatttt gcccacaaca gacaagtctc cggtaatccc taaagataaa
     2461 ccagttgttc caaacgcaga agttacttcg atgatgatcg agatcagcgt ttgttcttct
     2521 gtagcagata aaaaaacgat acaaaagaaa cacataccaa gagaaagcat aaagacaacg
     2581 actgattttc gcacatcatc ttgatcgatt ctccgtccaa aaatattgat gttatcttca
     2641 cttttgagga aggaatatag atacaaaccg atgattgcta cagtagttgt tcgaatcccg
     2701 ccgcctacag aactaggact gcatccgata aacatcagta aagaaaaaat gatcagtgtt
     2761 gtgatttgaa aatcacccaa atcgtgaatc tgcagaccag cattacgagt cgtaatcgaa
     2821 taaaacatcg aattgatcca tttgacactc atattggaat cttggaataa atggtccttt
     2881 tccaatagat aaatcaagac agttcccgaa acaaacaaga taacaaaagc taacacagct
     2941 aatttggtaa acaaggaaaa acgaaacgga agcttcgcat tggaacgttt gtataatagc
     3001 cattcccggc actccatcaa tacaggaaaa ccaattcctc cgacaaaaat caaaaacatg
     3061 atcaggatca agaaaaaata gtcatgtgca aagggcttga tggaatcccc agtgacgtca
     3121 aacccagagt tcgtgacagc cgatatcgcc tgataaaaac cgtaaaaaac ggcatcacgc
     3181 caacgatcaa aatagcctct gtaataaaaa taaatagaaa agaatgtccc aaaaagtaat
     3241 tgaaaccaga ttaaaatagc aaaagtgatc cgaatcagtc ggacgatacc agacaaacgc
     3301 ggttgattca tatccgtcat gatcagctgt cgctgtttca gtgtgatccg tcgtttagaa
     3361 aaaatgacaa aagcagtaga aatcatcatg atccccaaac caccaacttg aaataatatt
     3421 tccagcagta taataccgtt atcattgaac acagaattga tatcaaaagt cgatagtcca
     3481 gtcacactca ctgtactgat tgccatgaac agcatgtcca caaaagaaac atggctatct
     3541 ggttcgcgaa aaatcggcat ataaaataga acgagtgata agaccgtcat caatatataa
     3601 taaaaaacga tgatttggat cgatgagaaa tgattggcag caaacttctg tcctcgccgc
     3661 tgcagccttc gaaagaataa atcaacatgc acagtactat cctcctgaca atagtcgttt
     3721 ctaccagtat acaaggggaa ttaggaatac tcaaagaaat tatcaaacag ataacaatac
     3781 agctttcgat taaaatagaa atggcttata ataaggaaaa tcctagaaaa aagaaggagg
     3841 aggaataaca aattgattaa tgctcaacaa atcgtagaaa aaatgaaaaa tcaaaaaata
     3901 aattatgata cagttctgaa aaaaatgatc atgcaatggg agaaagaaga agtaaagcct
     3961 aagatattaa tacatacatg ctgtgctcct tgcagtacgc acacattgga attcatgtct
     4021 caatatgcag agatcacgtt atttttttca aattcgaata ttcatcctaa aagtgagtat
     4081 ttgcgaagat tacatgaaca aaaacgattt gtagaccaat ttaatgagaa aactgaccat
     4141 catgttgcgc taatcgttga tgaataccgt ccaaatgaat tcaccaaaat ggttttaaca
     4201 aaccatcttg aaaacgaaaa agaaggtggt gctcgctgca gtgcatgctt caatatgcga
     4261 ttagatcttg ttgcgcaaaa agcgcaagaa ctaggatacg attactttgg aagtgccctg
     4321 accatctcgc caaagaaaaa tgcagctttg atcaatcaga tcggaatgga tatccaaaag
     4381 atttacggga cacaatactt gccaagtgat ttcaagaaaa acaaaggcta tgaacgctct
     4441 ttgcaaatgt gcaaagagta tgatatttat cgccaatgtt attgtggttg cgtgttcgct
     4501 gccaagcagc aaggatgcga tctgaaagaa atcaatcggg aagcaaaagc ttacttaaaa
     4561 acatcaaccg tagtttttga ggaaaattaa agaaatcttt cggaaaaacg taagaaaaaa
     4621 ataaagaatt tatggtagaa ataaggtaga ctgtataatt tgtccgtagt aaagtaagga
     4681 aacaagaata aatttcaatg aaggaagaga taagatgcga aaagtagcac ctattttgaa
     4741 gccaatcgct gtattaacaa tctcgacgat tgtcgcgact actacaggta ttgtgaatag
     4801 ttccagctac cgtgcaccaa gttcaagttc tagtactgta gaagaaacaa caccaactac
     4861 ttcagtctcg acatctgaac caacaacaac ggaaagtttg aatgaaacca ctacgacaag
     4921 tacatgggac gatacaacaa ctagttcgtc gtatgatgag acatatacaa ctgacagctc
     4981 aagcgaaaca agtaatacgg taccagatgg cactccatcg gattcaacca atccaagtac
     5041 aagtccggat acaagtgcta gctccgaaac gataccaagc agtacgactg tagatgataa
     5101 cacgcaaaat gatgatgcag cacgtacagc acagcaaaac caagattcag gaaataccca
     5161 aacgtataac cagcaagcag gtgattctca atgacatttt tactagacct tatcaacggg
     5221 gtgcataaat tccttggcta tttagacatc agtcctaaat atcttaaccg tggatatacg
     5281 attttaagtg tgattcccac gctttattta ttgagaattg tttatggact ttggcaaaac
     5341 caaaactatc ttcaattttt cttatatgga cttgcatttc tagtgcttgt ttattttact
     5401 gttttaaatg tattttatta ctttttagat aaaaacacga aagccgatgt cactcagctt
     5461 tttgtgaagt atttacctga tgaagcgttc aacatccaga cagaagaatc gatagataat
     5521 ggaaattcga tcgataaagt gaatacacaa gaggtcatgg tttcttatga cgaagattat
     5581 caattgaaat tagccgagaa tatgcggtat ttgattggaa atggtgagat caaaacaaat
     5641 gaactcggtc gcatggatgg atttctggtc gatagaaata cattgtatcc ttattactat
     5701 gtcaagaaaa caggagagaa agagtatgtt ctaaatattg gacgaagcta ctcggacatg
     5761 gaaaaagtag ggaccattcg acttgactca acagaagaca cattggaacc tgtcggattg
     5821 ttcatcgtcg gcggtgattt tgtcaaagac gggttacgct atcatgagcc ttatcgtctg
     5881 aaattgattg caaaaaaggc acagtcgcag gaagaaccag tggtttatag tcgtagccaa
     5941 agaagaagac attcataatg tgatgaaacg ccgtgtatca gtggttgcga taaaaacgtt
     6001 tattcggaat aagggggatg tgacacgtct tttgtcacgt tcctttttta tataacgaga
     6061 aagataagac gaacacatca cttattcttt cctttcattt ataaacattg tagaataaag
     6121 aaagtacaac gaagtattgt gaaaaaacgt aataaataac gaggaaaata caagtaggag
     6181 gtaagctgtg aaagaatttt tgaaaaattg ggggattttg atccttgtat tagcggctat
     6241 tttattagct agagtgtacg tgtttacacc agttactgta aacgggcatt cgatggaccc
     6301 tacattaagt gatggacaac gattgatttc atctaagatc tcaaactatg aacgaatgga
     6361 tattattact acaaaggaac cgggggatga agaacggatg attgttaaac ggatcatcgg
     6421 tatgcctgga gatacagtca agatggaaaa tgaccagttg accattaatg gcaaaaagta
     6481 tgatgaacct tatctggatg agttcaaaaa agaattttca gaagataagt tacaaggaga
     6541 atatgcttat agctcaggat tccaagcaca agcagaaagt tcatccacct ttacgagtga
     6601 ctttgaatat actgtgccaa aaggaaagta tcttgttcta ggcgataacc gcttgatttc
     6661 aaaagacagc cgaatgtttg ggttagtcga caaagatatg atccaaggaa aagttgtttt
     6721 ccgttattgg cctctttcag aaattaaaat catgtgatga aaaaataaaa agaagctgtg
     6781 acatgttttt tgtcacagct tctttttccg aaaattcctt cttatttctt ggagttgctc
     6841 actttttttg caatctcatt ttaagctttt tggctgatgg ataagaaaag cgaagcgttt
     6901 ttgttcataa atagcttttc cccacgatgg aaggtatgac tagtagcaga gacaaagccc
     6961 gttttttcca atcgattatt caattcttct tggctaaagc cattatggac tttcggatga
     7021 ctaatttgtt cattcttgtc aaagtctacg atgatcaatt gaccgccagg agctaaaatt
     7081 tcataaagtt ttgtaagaat attctccgta tcaggaatgt gtaaaagtac aagtgataga
     7141 aggatgagat tagcttggac agcaggaaat tcgacagaag catcagcgtg gatcgttcgg
     7201 acatttttca gatctgctgc ttggatcttt tcttctgcca ttttcagcat agtttctgaa
     7261 gcatcggcaa tgatcagttc tttgaatctt tccgcaagcg gtaaactaac aagcccagtt
     7321 ccgcctccgt aatccagcag gactttttgg tggctgtcgc gcggtagata agtagttagt
     7381 tcttcgcgaa taatcttggc taatgcttga cggtcagggg aatcataatg gttagcgatg
     7441 gaatcaaaaa tattttttgt catcaaatag ctccttacgt aaaactttga aattttaact
     7501 tattatagca cgtgaaaaga aagaaagcat gctatactca attcaaaaag ggagaatcta
     7561 gaaagaatat gccgatatcg tttgtaaaag atagagagga aaaaggaaag tgtgtccgag
     7621 aaatattact agacttgcct gagtggtttg ggcttcctga atcaacggaa aaatatatcg
     7681 aggaatcaag taaactacct ttatggtgtg aaaaaagaaa agaagaatat ttaggcttta
     7741 tcactctttc acagacaagt gaagatactg ccgaaatcta ttctattgta tgggaataaa
     7801 aaaagactat catcaccaag gattaggaac aaaacttttt aaagaagcag aaggttacgc
     7861 agcaaaacat tacaaatatt tgcaagtgaa gactgtagac gaggggcact actctatata
     7921 tgatcaaact atttgtttct acgaatcatt aggattttca aggttggaag tttttccaaa
     7981 tttatgggat gaatggaacc catgtttagt tcttgtcaaa aaattggaac aaaagtgagc
     8041 aatagattta atactaatct gtgcttgatg aaaattctca ctgtaaaaaa tgctgaaaat
     8101 caagtataat accataggaa caaactggaa ggtgaaaaag agcatggcac aactattttt
     8161 taagtatggc gcaatgaata gcggcaagac gatcgagatc ctaaaagtcg cacataatta
     8221 tgaagaacaa aataagccag ttgtcttaat gacaagcggt attgatacaa gagatggttt
     8281 aggcgttgtt tcaagccgaa tcggactgaa acgtaatgcg atgccgatat ttgaagaaac
     8341 agacgtattt gacgtaattc agaaaatgga aagcaaaccc tattgtgtgc tgatcgatga
     8401 agcgcaattc ttaaaaaaga aacatgtcat tgcttttacg agaattgtgg acgaattgga
     8461 tattccggtt atggcatttg gtttgaaaaa tgattttcga aacgagttat ttgaaggatc
     8521 aaaatattta ttgctttatg cagacaaaat cgaagaaatg aaaacaatct gttggttctg
     8581 ccacaaaaaa gcaatcatga atttacatta tattgatgga aaccctgttt atgaaggcga
     8641 tcaagtgcaa attggcggaa atgaagctta ttaccccgtt tgtcgaaaac attactttca
     8701 cccatcaatg attacagaag gagaataagc atgtacgatc aattacaagc aattgaagac
     8761 cgttatgaag agcttggaga acttttaagt gacccagaag tgatttctga tacaaagcgt
     8821 tttatgcagc tttcaaaaga agaagcaaac acgcgcgaaa cagtcgaagt ttatcgtcgt
     8881 tataaagaag tagtacaagg aatcaccgat acagaagaac tgcttggtga aaaactggat
     8941 gatgaaatgg ctgaactagc aaaagaagaa ttatctgaat taaaaaaaga aaaagaagtc
     9001 ttagaagaaa aaatcaagat cttgctttta ccaaaagatc caaatgacga taaaaatatc
     9061 atcatggaaa tccgtggagc agcaggcgga gacgaagcag cattattcgc tggcgatctt
     9121 ttcaatatgt accaaaagta tgctgaagca caaggctgga aaacagaagt gatggaagct
     9181 aacgttaccg gaatcggtgg atataaagaa gtgatcatga tgatcaccgg agacaacgta
     9241 tattcgaaat taaaatatga aagtggtgcg caccgcgtcc agcgtgttcc ttcaactgaa
     9301 tcgcaagggc gtatccatac ttccaccgca acagttgtcg tgatgccaga agctgaagaa
     9361 gtagagatcg atattgaaga caaagatatc cgtacagata tctatcatgc ttcaggtgct
     9421 ggcggacagc acgtcaataa aacagcatct gctgtacgtt tgactcactt accaacaggg
     9481 atcgttgttg ctatgcaaga tgaacgttct caaatcaaga accgtgaaaa agcaatgaaa
     9541 atcttgcgtg ctcgtgtgta cgataagatc cagcaagaag cacaaagcga gtatgatgcc
     9601 aatcgaaaat cagcagtcgg aactggggat cgttcagaac ggatccggac gtataatttc
     9661 ccgcaaaatc gtgtgactga tcatcgtatc ggattaacta tccaaaaatt agatcagatt
     9721 ttagcaggga aattagatga gatcgttgat gcattgatca tgtatgatca aacatcaaaa
     9781 ctggaagcta tgcaaaatgg gtaaaatgac ctatcgagaa gtcctgtcac gggcttcttc
     9841 ttttttagag gatcatggga aagaagcata tagtatccaa tttttatttt tggaacgaaa
     9901 acaatggaaa aaacttgatt ggctccttca tatgaacgaa gagatttcag aagaagaaca
     9961 gcggttgatc gaaaccgatc tgcgacttct gcttgcagat catccacctc agtatttgct
    10021 aggatatgca gatttttatg atcatcggtt aaaggtaact gaagcaacac tgatccctcg
    10081 accagaaaca gaggagttag tcgaatggtg tttagacgag acgcctggtg taccgttaga
    10141 agtgatagat attgggacag ggactggagc aattgctatt agtttgaaag cagcaagaaa
    10201 aaattggcat atatctgctg tggatctttc agaagaagca ttagaagtag cgaaagaaaa
    10261 tgctcagaaa gaaggaacga aaatcagttt ttatcatgga gatacattag gaccagtaat
    10321 ggatcagcaa tttgatgtga ttatttctaa tccgccgtac atcagtcgga atgaatggga
    10381 actgatggat gaaagtgtcc ggtcattcga acctaaaatg gccctttttg ctgagaacga
    10441 tggattagct atttatgaaa aaatagcagt tgaagcacca agcgtactaa aatcaaatgg
    10501 aaagattttt ttagaaatcg gatttcgcca aggtgaagca gtaaaaaaaa tatttcagca
    10561 agcatttcca gataaaaaag tggcgataaa aaaggatctt tttggcaatg aacgaatgat
    10621 ccaagtttat ggttgaagtt gtggatgaaa aattttttat ttgttttttt attataaaaa
    10681 aacacttatt tgacaaggat gtaaacgact ttttggttta tcaacaagtt tatccactat
    10741 tgacaaatag attatccaca aacagtggaa aacttgagga taaactcaga caaaataaga
    10801 atgtatgaaa aaggggttgt ggataaactg tggaaacgaa acgatatgat gaaacagaat
    10861 tgcaagaggc agccgaagca ctgaaagaag gagaacttgt tgcttttcct accgaaacag
    10921 tatacggatt gggcgccaac gctcttttac caaacgctgt caagaaagtg ttttctgtaa
    10981 aagggagacc gcaagataat ccattaatcg tccatgtcgc ctcttttgaa caagtaaaag
    11041 agtatgtgga caactttcat ccggcagcag agaagattgt gaagaacttc tggcctggac
    11101 cattaacttt gatatttaag atcaaaaaag acactttgcc ctcagttgtg acgggaggat
    11161 tatccacagc tgcatttcgt ataccggata acaaaaaaac actagaagta atcgaacttt
    11221 ccggtgttcc gcttgtcggt ccaagtgcaa atacgtcggg aaaaccaagt ccaacgactg
    11281 cagatcatgt atatcatgat ctacaaggaa aaattaccgg gattattgat gatggagcta
    11341 cgcgaattgg tgtagaatcc actgttcttg atttaagtga tccaacagcc atgcctatga
    11401 ttttacgacc aggtgcagta acgaaagaac aaatcgaagc agtcatcgaa tctcctgttg
    11461 ctattgatca gcatcttgta aaagaaaatg aaacaccaaa agcccctggg atgaaataca
    11521 aacactactc acccgataca cgtgttctga tggtcagaga tggcgattgg tcaactgcag
    11581 ttcaatgggc aaaaaataag aagatccgtg caggtgtcat agcaagcccc gaaattgcgg
    11641 atcaagtgcg gacagatact gcagctgttt atatgtataa cgacaactca gtagaagcgg
    11701 cggctaaagg attgtttgca ggtctaagag gattagatga accaacactt ggattagatt
    11761 tgatttttgt acaagtgtat ccagaaactg gattggggaa tgcttacatg aatcgcttga
    11821 aaaaagcagc aggacaaaat tattttgaaa aatgatcaat tggttattgt cgcattcttt
    11881 tagtatgata caatgctatc aagtaaatct tctatcagtg aacgaaaaac taagcgtaac
    11941 taatcgtaat agaagagata cgaatatttg gcaatttgtt tttgatggga aaaataaaat
    12001 tgtaggaaaa taaaaaggag ctgttgtttg tggtagatta caaaacgttt gaccctgatc
    12061 tttgggctgc gatcgccaaa gaagaagaaa gacaagaaca taatttggag ctgattgcct
    12121 ctgaaaactt tgtctccgaa gcagtgatgg ctgcacaagg aagtatcttg acaaataaat
    12181 acgcagaagg ttatccaggg catcgctatt atggtgggtg tgaatttgtc gatatcgttg
    12241 aaaatttagc gattgaccgt gcaaaagaat tattcggagc gaaatttgcg aacgtccagc
    12301 ctcactccgg ctctcaagcc aacacggctg cttatctcgc tttggtagaa ccaggggaca
    12361 cgatcttagg aatggatctt tccgcaggcg gacatctaac acatggatca ccagtcaact
    12421 tcagtggcaa aacctatcac tttgttgctt acggtgttga tccgacaaca gaagttattg
    12481 attataatgt ggtacgtatt ttagctagaa aacatcaacc aaaattgatc gtagcaggtg
    12541 ccagtgctta cggacgaacg atcgactttg cgaaattcag agaaatcgca gatgaagtag
    12601 gcgcaaaact gatggtagat atggcacata tcgcaggatt agtagcagca ggacttcatc
    12661 ctaatccagt tccttatgca gatatcacaa cgactaccac tcataaaaca ttgcgtggcc
    12721 ctcgaggcgg catgattttg acaaacgatg aagcattagc aaaaaaaata aatagtgcgg
    12781 tatttcctgg tattcaaggc ggccctctag agcatgtgat tgcgggtaaa gcagtagcat
    12841 tcaaagaagc attagatcct gcatttaaag aatatagtga acaaatcatc gccaatgcaa
    12901 aagcaatggt caaagttttc aatcaagcaa ttggaaccag agtcatttca ggggcgacag
    12961 ataatcatct gatgttgatc gatgttcgcg agttaggtat aaatggaaaa gaagcagaga
    13021 gcattttgga cagtgtgaat atcactgtaa ataaaaactc gattcctttt gaaacactaa
    13081 gtccattcaa aacaagcggt attcgaatcg gcacgccagc aatcactact cgcgggttca
    13141 aagaagaaga tgctgtaaaa gtggctgaac tagttgtcaa agcattacaa gcaaaagatg
    13201 ataacgctca actagacgaa gtcaaaacag gtgtacgcga attaactgaa aaatttccgt
    13261 tgcataaaaa ataaaaattt aaattccatt agtaaacaga aaagttcaat gttgggcttt
    13321 tctgtttatt ttttgggaaa acggattctt tgacaatatc ggtgatgctc tctagtatat
    13381 gaggtgtaat tttagtcttc acactaaatc tcagggagga aaagtcatga ctgatcgtat
    13441 ctcgttagaa aaggaagcag tagcattcag tgatgcaaat gcgcctcatc cgcgtatcta
    13501 tgaactagca ccggaagaag gaagagtttt actagaagaa gtacaagaat cacctgtgaa
    13561 caaatattcc gtcgatattg aagacttgat ggtggatact ggcgaatggg gaaaactcaa
    13621 tattcgtctc gtacgaccag aagggaatat ggataaatta ccagttattt tttatattca
    13681 tggagcaggc tgggtttttg gcagtgctca aacccatgat aaattgatca gagaacttgc
    13741 ggttcgtacg aattccgtcg ttgtctttcc agaatatagt cgatcaccag aagcaaaata
    13801 tccaacagca attgaacaaa attatgctgt gttgcaacag ctgaataaat tagccaagtc
    13861 aaaaaatctg gatctcgaga atctaatcgt tgcaggagat tcagtaggtg gtaacatggc
    13921 tacagtcatg acgatcttaa caaaagaacg aaagggcctc ccaatatcca agcaattgct
    13981 gtattatcca gtcacaaacg ctgattttga tacagattcc tatcatgaat tcggagaaaa
    14041 ctattttttg acaagagaag gaatgatgtg gttttgggac caatatacga cgaatgaaga
    14101 agagcgtgct gaaatcacag cttcgccttt gagagcaaat ataaatgaac taaatgatct
    14161 tccttcagca atgattttaa cgggagaagc ggatgtatta agagatgaag gtgaggctta
    14221 tgcgcgcaaa cttcgtgatg caggggttcc tgttacacaa gtacgcttcc aaggaatcat
    14281 ccatgatttt gtcatggtaa atgctatgga tcagacaaag gcaacgcgtg cagcaatggc
    14341 attatctact tcttggatca agaaaaaaga ataagctttg cttgtccgca ggaaaacttc
    14401 ttttcaaaaa cggattttct taggaaaaat ggcgagtttg actagtcaat cacttgattt
    14461 tgttttacaa ttaaaaagaa acgacagaac aaaggagagc ttaaaaaatg ggcaaatttc
    14521 aagtgatcga tcatccattg attcaacaca aactaactat tattcgggac aaaaactgcg
    14581 gaacaaaggt ttttcgtgaa gtagtcgatg aaatcgctat gttgatggca tatgaagtat
    14641 cacgggatat gccattggaa gacatcgtga tcgaaacacc gatcactgaa acaacacaaa
    14701 aaacgttgtc tggtaaaaaa gtagcgatta ttccaatctt gcgcgcaggt attggaatgg
    14761 ttgacggtat cttggaattg attccagctg ctaaagtggg acatatcggt ctttatcgag
    14821 atgaagaaac attggaacca catgaatatt tcgtcaaact tccagaagac attgatgcac
    14881 gtcagttgtt tgtagtagat ccaatgttgg caacaggcgg atcagcaatc atggcaatcg
    14941 atgcattgaa agaacgtggc gcgtcgaaca ttaaatttgt ttgtttggta gcagcacctg
    15001 agggagtaaa agctttgcaa gaagcgcatc ctgatattga catctataca gcttctctag
    15061 atgaaaaatt gaatgaacat ggttatatcg ttcctggact aggggatgcg ggtgaccgtt
    15121 tgtttggtac aaaataagta aatacgaaaa agggtgtgac acaacttttg tcacatcctt
    15181 ttttggtcat ttttaacgtt tgatgcagaa cagctttttc acagctttcg tttgcatata
    15241 aaaaaaccat cccaaaaatg cagagatggt caaattcaaa tcttttttag ttctttgtag
    15301 ttaacgatta ctacaccctt actttgcgtc atcaagttcg cattttctgc agtttcatca
    15361 atctcaacaa cagcggaatt tttcaattgc tttgaaatcg ttccagtttg cgacttgccg
    15421 tgaattgtga acattacgtg agtattgatc ttgaattttt caccaatttc cgatggtacg
    15481 atagttgtat caaattttcc aaaagttgcc attttcataa aacctgcctt tcacatcaat
    15541 tataccacgt tttatgaaaa atatcatgaa attaaactaa ttttccatcg gactctttac
    15601 aatcagccaa atagagtata taatttcttt tggataaggc cagcttagct cagttggtag
    15661 agcaacgcac tcgtaacgcg taggtcgtag gttcgatccc tatagctggc attaaaagag
    15721 aagacagata tatcaaggat ttttaatcca ttgatacatc tgtctttttg tttaaaggaa
    15781 ataaagtatg ctttcttagc aatagagcat gtattatttc tataaaaatt taggagaata
    15841 aaacgactag caatatagct gtgaaatcaa atatcacatg aactgcccaa cttgtaatga
    15901 tcgagttgct tttaatggca gcttggttga ataacaatct tgccacccct tgtatcaaaa
    15961 ggatgtgtgc tacagtgtgt aaaatatttc cattatcata agtactgtaa tggataaatc
    16021 caaagatgat tgctgacaag aaactagcga caggaatgct gaacttacta gaaaaaatag
    16081 cgagaaaata cactgagaac aattcttctc caagtatcat gataggcaaa ataataaata
    16141 ataacgggct gaaagcctca tttattggat tgcctgttaa accccatttc aaaatttgtt
    16201 gcaaaaatac cgagactgcg gcactgatta ctacattgat aaaaaaatat ttggctatat
    16261 ttttgacagg agcgacaggt ttcgagaaca tttttttcgt atctttttta ccaaaaacaa
    16321 gtgtaaatgc tataaatcca gtgatagtta aagaaaaaat gctaataatg gatggcgcaa
    16381 atagcaaccc taacaaaccg agtacaacga caatagtgcc caatatccct tttttaagtt
    16441 ctattttttt tcctaaaatg ttattcatga taataactcc tactattcag tttttgaaga
    16501 tagagtcagt atacatgaag agttaaaata ggcaatgttt ttttatggat atttgtattg
    16561 ctaaaaattt atcttatata ttcattttga ttatactact tttatttgta aaaattttct
    16621 agcaaaacca agtgcttgca actgattaag cgtacaattt tttagatgtt ccgagcgtac
    16681 ttcaatcatt tcaaaggagt tgctacttaa atcgatattt tttaaatcag tatcaaaaaa
    16741 gctagcattt tctaaatcat tagtagaaaa cattatttta gtgagggaac agtctacaaa
    16801 atctgcgctt gataagacag agtgctcaaa ggtactttct tttatgtttg aaccagataa
    16861 atttacatag tccattttac aattctcgaa taacgtgttc ccaatataac tttccatcaa
    16921 tttagtacct gttaatttac aattgacaaa tttcacgcga tgcaacatgc tttttgtcaa
    16981 tatacagcct gaaaaatcac agttttcgaa tatacagtcg gtaatctcca ttctttgaaa
    17041 atcattggaa gcaaaaaatg catacttgaa aatagatttg taaataattg gatggcagat
    17101 tatttggttt tcgatgacct ctttttgtga aaggatatta tacagttcaa aatcttcgtt
    17161 ttcatagata tgaaaaaagg atcctttatt caagcttgct tcattaactt taggaaaaat
    17221 catatttaat tacctccatt ttcataaagt catattaaca aaagctaaac caacttacat
    17281 tagcagaaaa tgagataggt tttcgccttt ttcgataacg atagtgtcgc tatctcttga
    17341 aacgttctta gaattgccct gagagacaca aattaggcgt aattctaata aaaatcttag
    17401 aataaaaatt tttactgatt taatttagaa tgtttttaaa ataaaaatcg ttgccataac
    17461 agtgtattga aaggttttaa caatccagta atgatttaaa aaaatctaga tgtagcgtat
    17521 actttgttta tagaatgtag tgggaagaaa tatatttttg ggaggaaatc gtgatgtcta
    17581 aaagtgaaga aatagaaaac atggtactaa aattatatga tctcgtttta aatccagaga
    17641 tcaaagaaaa ggaacgtata cttttgatag acgcaaagac aggcttagaa aaaggtcagt
    17701 attatcctaa agtcataaat aatttggaac gtagtttacg tccgttagca atcaggggag
    17761 aattgtctaa accagtatca ccgttttata tggagatatc aacaatagga aaatttgaaa
    17821 aagaattagg tcgaggaatg gcttcggcac cgattacttt tgggcattta taaaaacgag
    17881 ttattcatct caatgaatta aaaagtatag tcaatctcat aatgcaggct aggttcattt
    17941 atttgaacag agtctgtatt tttttattct aaataaagaa acagatgttt ctttatattg
    18001 tattttatcc tttaattaac acaaaaacag ctagtataaa ctaataatgt taattaaaag
    18061 tgtattttat gaaactatcg ttatttatta atgttgcatt tttgtaagtt aaaaattgga
    18121 aatat
//
LOCUS       DAZULR010000049        18050 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.050, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000049 DAZULR010000000
VERSION     DAZULR010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18050
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.050"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            82..1377
                     /locus_tag="ACG8ZV_002121"
     CDS             82..1377
                     /locus_tag="ACG8ZV_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa5 family transposase"
                     /protein_id="HFS4997408.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKNCQVSLTTVIRTLKEFKSYLPKQSK
                     RILPRVLMVDEFRSHASIEDKMSFICADGETGQLIDVLPTRKLPRLTSYFLGCANPEE
                     VKFLVTDMNAAYFQLTKRILPNAKVVIDRFHIIKHMNQAFNELRIREMNELRKVGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLGFSTSLKEAY
                     PYFHELVEAFRDKDPDLFFSLLAELPETLDDGFREKLQNLLTYEEGITNAMIYPYTNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQLIKVR"
     gene            complement(1542..2249)
                     /locus_tag="ACG8ZV_002122"
     CDS             complement(1542..2249)
                     /locus_tag="ACG8ZV_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HFS4997409.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(2328..2666)
                     /locus_tag="ACG8ZV_002123"
     CDS             complement(2328..2666)
                     /locus_tag="ACG8ZV_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HFS4997410.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            complement(2777..3739)
                     /locus_tag="ACG8ZV_002124"
     CDS             complement(2777..3739)
                     /locus_tag="ACG8ZV_002124"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HFS4997411.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            complement(3754..5085)
                     /locus_tag="ACG8ZV_002125"
     CDS             complement(3754..5085)
                     /locus_tag="ACG8ZV_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DRTGG domain-containing protein"
                     /protein_id="HFS4997412.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            complement(5093..5773)
                     /locus_tag="ACG8ZV_002126"
     CDS             complement(5093..5773)
                     /locus_tag="ACG8ZV_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HFS4997413.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            complement(5992..6471)
                     /locus_tag="ACG8ZV_002127"
     CDS             complement(5992..6471)
                     /locus_tag="ACG8ZV_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HFS4997414.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            complement(6598..8277)
                     /locus_tag="ACG8ZV_002128"
     CDS             complement(6598..8277)
                     /locus_tag="ACG8ZV_002128"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HFS4997415.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            8825..10327
                     /locus_tag="ACG8ZV_002129"
     CDS             8825..10327
                     /locus_tag="ACG8ZV_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4997416.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVTVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            10340..11002
                     /locus_tag="ACG8ZV_002130"
     CDS             10340..11002
                     /locus_tag="ACG8ZV_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4997417.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(11103..11306)
                     /locus_tag="ACG8ZV_002131"
     CDS             complement(11103..11306)
                     /locus_tag="ACG8ZV_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HFS4997418.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(11417..12601)
                     /gene="iadA"
                     /locus_tag="ACG8ZV_002132"
     CDS             complement(11417..12601)
                     /gene="iadA"
                     /locus_tag="ACG8ZV_002132"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008798 - beta-aspartyl-peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HFS4997419.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            complement(12758..14497)
                     /gene="yfcC"
                     /locus_tag="ACG8ZV_002133"
     CDS             complement(12758..14497)
                     /gene="yfcC"
                     /locus_tag="ACG8ZV_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HFS4997420.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            complement(15270..15884)
                     /locus_tag="ACG8ZV_002134"
     CDS             complement(15270..15884)
                     /locus_tag="ACG8ZV_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFS4997421.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(16490..16867)
                     /locus_tag="ACG8ZV_002135"
     CDS             complement(16490..16867)
                     /locus_tag="ACG8ZV_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997422.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(17167..18048)
                     /gene="galU"
                     /locus_tag="ACG8ZV_002136"
     CDS             complement(17167..18048)
                     /gene="galU"
                     /locus_tag="ACG8ZV_002136"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFS4997423.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
BASE COUNT         5307 a         3850 c         3106 g         5787 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcacgac aaaataaaca
       61 actgagagga cgatatgcta tatgaatgat tctatcaaaa aaatgctgcg attaatagag
      121 aaagatttga tgattacaga ggtctcttac gagacctttc agaagaaaaa gacgttgatc
      181 gtcgatgctg ttttctcacc tgctccccat acctgtagaa attgtggttc tactgtggta
      241 gatggaaacg ggaaagtaat tgtagtgaaa aatgggaaga aggaaacgat tgtccgcttt
      301 gaacaataca atcacatgcc tttggttatg cgcttaaaaa agcagcgcta tacctgtaaa
      361 aactgtcgaa cccattggac ggctcaaagt tattttgttc aacccagaca ttcaatcgcg
      421 aatcatgtca gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaaatt gtcaggtatc tttgaccacc gttattcgta cgttgaaaga gtttaaaagc
      541 tacttaccaa agcaatctaa gaggattctc cccagagtat tgatggttga tgaatttcgt
      601 tcgcacgctt ccatagaaga taaaatgagc tttatttgcg cagatggcga aacaggacaa
      661 ttaattgatg tcttgcctac gcgtaaattg cctcgattaa caagctattt cttaggctgc
      721 gctaatcctg aagaagtaaa atttttagtc acagacatga acgccgccta cttccagctt
      781 accaaacgta ttctgccaaa tgcgaaagta gtgattgatc ggtttcatat tatcaaacac
      841 atgaatcaag cctttaatga gttgcgtatc cgtgaaatga atgaacttcg taaagtagga
      901 cagaaaagtc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagttttc gagcaccaaa atacccattt
     1021 cttacggaag cgatgatgat tgatcgattg cttggctttt ctacgtccct gaaggaggcg
     1081 tatccctatt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacggct ttcgggaaaa gctccaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcgatgatct atccttacac caatggaaaa
     1261 atagaagcga agaataccca tataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg atcaatcaat taatcaaagt aagataacaa
     1381 aaaatctgag ccagaatgag gttcattctg acccagattt gattttgtac aacccatcag
     1441 tccttattga caaagagccc ttattccaaa taaatggtat tcaatcagct aactctcggt
     1501 attagctcag atcaaagcgc tgatttcaca acttctttat tttaatctct tcggttgccg
     1561 ccgaacaata agatcaagcg caacagctgc aggaatgtcg aaagcgctgc tgcaacataa
     1621 gtcagtgctg ctgcaaataa tacgtgtctt gccatcggta cttcttcttc cgtcagtagt
     1681 ccgccttcac tcaaaatttg gattgctcgc cgagacgcgt taaattcgac tggtaatgtc
     1741 accaattgga aaagtaatgc taaagaaaaa gcgaaaatcc cgatattgat taacgtagag
     1801 ttccagctaa gcaatacacc taccataatc aaggggaacg aaatcatcga accaaagtta
     1861 gctgctggaa caagtgctgc acgaatcttc aatgggacat aacccgaagc atcttgtacc
     1921 gcatgtccgc attcatgagc tgctacacct atcgcagcaa ctgaagtaga ctgtgcagtt
     1981 gcttgagaca aactcaacat cttattacct gaattgtagt tatctgtgag atctccggca
     2041 atttgttgaa caccgacatt atttatctgt tgactttgta atatatattg tgctgcttgt
     2101 gtaccagtca cattgttttt gcttctcact tgatcgtatt ttcggaaagt actattgacg
     2161 tacgctgacg caattccgga aataactaat ccaagaatga ccaaaagaaa tgtcggatct
     2221 aaaaaaccat acattccata accatacatt ttcgtttcac tccttttcgt ttactttatt
     2281 ttatcattag tagtaggaaa agaatgtgaa aagaccttga atattcttta attctttttc
     2341 acaaattccg atttcagttt catcggtcca aatccttcta ccttgcaatc gatattatga
     2401 tcgccttcta ctaaacggat gttcttgact tttgttcctt gtttaatggc acctgacgca
     2461 ccttttactt tcaagtcttt aatcactgtc acgctatcgc cctctaacag acggtttcca
     2521 tttgcatcta ataccactaa tccgtcttct atgacagttt cttgttcttc tttgttccat
     2581 tcgttcccgc attctgggca aatcaacaag cctcgatctt catatgtgta ctctgagcca
     2641 cattctgggc aatttggtaa tgtcatcttc tttctccttt aaaatcttta gtgagcacta
     2701 ttgtaacgga aaaagaagat cttgaaaaga tacatttgtg atttttacta caaaaggcac
     2761 gttttcgaac gaagtatcat tctgtttttc tgctcttata cgattggcat atatcttgga
     2821 tctctttata gatttcctct acttctgcta aatcttttgc attcgcacca cttgctaatg
     2881 gatggcctcc tccatgatgg cgtttagcca attcattgat gatcggcccc ttagaacgta
     2941 aacgtacgcg gtaataccct gaaggctgct gaacaaaaat cccccaagcc agcacttcgt
     3001 caatcactcc aggaagtgaa acgatcgaag ctgtctctga atcatcgatt ccatatttat
     3061 caagaatttc ttgcggaagg attattcttc ctgcaccatt ttcatccacc tggatatttt
     3121 gataaagata accggaaagt ttagcgactt tcatcggcat ttgttcaatc tctctgttca
     3181 aagcacttgc atcaaatgga taatttctca atatcgaagc aatctctaat gtacgggacg
     3241 tcgtggaggg atacaaaaag cgccctgtat ctccgacgat tcctgcataa agtaaccgtg
     3301 cagccttaac gttcatcttt aaagattcag gaaacatcaa agcaaattct gcaatcatct
     3361 cactacagct acttgctttt gtatttaccc acacaagatc tccataaggg tcatcattgg
     3421 gatgatggtc gattttgatc agtttttctg ccaactgata tctttgatca ctgattctgg
     3481 gtgaattagc tgtatcagtc acgatgacta gcgctccttg gtagaagaca tcttcaactt
     3541 cttgcatttc tgctaaaaag cgaagccctt caatcgtttc acctacttga cgtatttctt
     3601 tttctgggaa actttcccgt aatagttcgg ctaatcctac ttgtgatcct aatgcatcag
     3661 gatcagggcg caaatgcctg tggataatga ttttatcgta tttttttatt gtatctacta
     3721 tttcttgctg tactgtcatt tcactcctgc tttctaagaa cgttccatta cttgacaaac
     3781 aacgattgct ttggaaacga tggtgttttc aataaacact tcgatatcca gtttagcgga
     3841 acgtctgccg atttccaata cacgtggacg aatgtctaat tcgctttcca attggatcag
     3901 ccgcaaataa tgtaggttca cttgttcaat caagatattt cgtttttggt tcatcaccat
     3961 tgttttttgt gcgacatcag aaatgatttc gctaagtacg ccaaaagaaa tggttccaac
     4021 gccattgacc atttgtggtg ctactacgaa tttgaactta gggttttcca aacgatttcc
     4081 ttcacggtca gtatcaatcg tatggatatt tccagatatc tgatccgaaa tcgtatctgc
     4141 aatctgcggt tgtcgctgga caagctgcat cgctttcatt acatcttgcc gggtaatcaa
     4201 gccttccaat gtcaagtcat cggaaacgac cggcatgact tctagcccat cccagatcat
     4261 ttgatggcta acagaggcaa tactcattgt tttctttaca ctgattggtt ctttcgtcat
     4321 cacccgatcg atgatctggt ttggcgattt ccctaaaaca tcttttgccg taacaatccc
     4381 catcaaacga tgatggcggt tgacgactgg aaaacgcgaa tgctgcgttt cttctgacaa
     4441 acgctgataa tcagaaatcg tatctgtctg ctgcaaataa tgagtctttt cagctggcat
     4501 atagatatca ctgacaagca tgatatcttt tttgatcaat tggtcgctta acgctcggtt
     4561 gatcatggtt gcgactgtaa atgtatcata agaggtgcgt aagatcggca tttcaagatc
     4621 atcagctagc tttgcaatct cagcagtcgt attgaatcct cctgtgatca atactgcggc
     4681 gccatcttcc aatgctaatt tttggacttc cgcccggttg ccgacgatca ttagtgatcc
     4741 tggcgtaata tagcgttcca tggcatgttt agtcatcgcg ccgatgacga atttattcaa
     4801 gaccttgtct aatcctgccg ccccgcctaa aacgtcccct tcaatgatcc tgacgacctc
     4861 gccaaatgtc aaacgttcaa tatgtttttt taatttgcgt tcgatacgga tggtccctac
     4921 tcgttgaatt gttgaaacta gtccgacatt ttctgcatct ttgattgcac ggtacgctgt
     4981 tccttcactg acattcaatt cttttgcgat gcttcttaca gaaattcgat tgccaacagg
     5041 taaactttca atatattcta aaatcaaatc atgttttgtc gccattttct gcctacactt
     5101 ccagcgtttc cgagacgctc attatttttc cttcactatc ttccagtaac tctacaaaag
     5161 attcgggatc ttgttcaatg acagggaaag tattgtaatg gattggaact actttcttgg
     5221 cacgaattgt ttgcgcagcc tttgctgcat cttctggccc catcgtatag ttatcgccaa
     5281 tcggcaagaa agcgacatca atatcgaatt cttctgcaag caatcctaga tcactgaaat
     5341 aagcagtatc ccctgcatga taaatcgttt ttccttctgc ttgaataata attccgctag
     5401 gctcgcccat atactgaacg ataccgtcta cttcatagct tgaactatgc tgtgcatgta
     5461 cgaattttac cacgccgaat ggaaacgcat gttttccacc gatattcata ccgaatgaat
     5521 ctactcctct gctgttcgca taatcagcaa tctcaacaat actgataatt gtggcttgat
     5581 tttcttttgc aataggaatc atatctccta tgtggtcact atgaccatga gtaatcagca
     5641 accaatctgt ctttacttct tctgcagtta agtctgtcaa tggatttcct gtaataaacg
     5701 ggtcaatcat cacgcgttgg ccattttcca tttcaattgt taaacaggaa tgtccatgat
     5761 acgtaatttt catattttac acctcgcgtt ttctctgtat cttttttatt aaaaacgatt
     5821 tcatcacttg cacatcaatg aaaaaatata gctgctaaat atattttcat tggattgata
     5881 gtacagtatg tacaaagcaa ttgtaacaga taatacagga tgcaccaagt accaagcaga
     5941 tataatctca agtttgaggt ctctgctctg cttagcttct cttctcgtcc cttaactaat
     6001 taaatcagcg taaataggat ggacgatctt ttctaaatcg gctactttta tccgaaggct
     6061 tctcccgatt tcaccgcttg acacaattac ttcttctttt tcttttaaag aactgtctgc
     6121 taaaaaacaa taatcaggat gtgcgagttt tattccaata ggggtgtttg ctccgtgggg
     6181 atatcctgta tgcattaata caaaatccat tccaggaaaa ccaactttac gatctttcgt
     6241 cacttgtctc gtttttttgt aatctaagtg atcgttcaaa ggaatcaatg cgatgatcac
     6301 cccagttttg tttcctttca ctacgagagt tttacatatc aaagctggat caatccctct
     6361 tttttgtagt tcttctgtga aagattcttc taccacatga ctaaaatcaa gtggttgata
     6421 gctgatcttt tgttcttcta aataacgttc gacttttgtt tgactcatca ttgattcact
     6481 ccctttattc tatcgtttat tataaagcga gggatgctgt attcaaaaat tatttgtttt
     6541 tcgcaaaaaa agagcaagac gagcactcta tagagaggtt catcttactc tttttgttta
     6601 ttttttattt cgacgttgag tagcttccat aatgactggc aagatcactg ggcggcgttt
     6661 tgtttgttca aataagtaac ggcctaattg atctcggatg tcttgcttta atttgctcca
     6721 ctcaaaatca ttgctttcta aatgtttctc aacgattgtt tcaatcatat tgctgctttc
     6781 tttcatcaga tcacggctag cttttacgta aacgaatccc cgtgaagtaa tttgaggttt
     6841 tgaaatgatt ttcttttctc gccgactgat agtgacaacc gctacgaaaa tcccgtcttc
     6901 tgacaagatt tttcgatcac gtaaaacaat gtttccgata tcacctatgc ctaatccatc
     6961 aatcattaca ttttctgcac ttgtagttcc tgcaacactc atacgcttgt tcttatattc
     7021 cagcacgtct ccgcgtccag taatatagat atttttgtat ggcatcccta ctgcatgagc
     7081 caaatctgca tgagcagcta attcacgata ctctccttga actggcacaa aatatgttgg
     7141 tttcatcaaa ttgatcatta attgcaagtc attaggattg gcatggccag aaacgcgcat
     7201 attctcagag atcaacttca ctgttccacc agctcgataa atgatatctt ccgttttcgc
     7261 cacgatggtt tccatcgcga tgcttggcgt agtagtgata taaaccaaat ctccttcttc
     7321 aatcttgaca ttacggtgtg taccgtttgc cattttttgc agagacttga tgggttcacc
     7381 cattcggcca gtttctaaaa tgatcagttc ttctggatca tagtttttca tgtctttcaa
     7441 cgtaacaagc agatcttcac ttggtaattg aagtttttct aaacgcatcg ctgtgcgaat
     7501 aattcgttcg aaatcttgac cagtcaagac aacttttcgt tgtgcttttt ctgctgcatc
     7561 caatacttgt tgcactcgtt gcaaattact tgctacacaa gcgacgatga tacgcccttc
     7621 ccaatatttg atcgtatcaa atacttcatc tgctatttgg gcttcagaag ctacaggctg
     7681 aggattttct gcatttgccg attcacttag taaggctaag actccttctt tgccgatttc
     7741 cgccaatcgt gcataatctg tttgatacat tgggatagcc gtttggtcaa atttaaaatc
     7801 tcccgtataa acgatactac cttcttttgt tttcagattg atccccactg aatctggtat
     7861 cgtatgagtg gtacggaaaa agctcactac tgtttcacca aagtctattt ctgtatgctc
     7921 atctaccaca tggaaatcct taaatccttt ggctgcttca ttacgactga cattcaattt
     7981 tgctaactcg atcgtcaact ctgtcccgaa tactggtaca gaaatttttg acaacaagta
     8041 aggaagtgcc ccgatcgcat ctgcatgtcc atgtgttaaa aagacaccag ctacacgatc
     8101 aatgttttct tctaaatacg taaaatcagg gattacgacg tcgatcccca acaactcatt
     8161 ttcaggatat tttagcccac aatctaaaat aaaaatatcc tcgcccactt ctgcgacata
     8221 catgtttttt ccattttcac gaacgccgcc taatgggata attttaatgg tactcacaaa
     8281 cttcacctct tcttatgaca tccaagttta aagatgtcga ttttcttctt tatctaaata
     8341 tatgagccat tccaatgaag catatgcaaa atcactattt ctcaacttat ggagaatcag
     8401 caggaaaatt accagcacat ccgcgttctg acagttggat gggcatttta ttttggatat
     8461 acttcattaa caaaatggat cttttgcgaa acgctatagc cagaatactt atataagtat
     8521 tcagctgttc cccattatta tacaacaaat aaactaaatc gctagtatca gcaattgtta
     8581 gaacaactat gcacgtaaaa atccctctgt agcatctagg atttcttttg ctattcctct
     8641 ttcatttctt cttcgtcggt ttgaaacata cttttttcat tttaccacat tttttgcaat
     8701 aactatagtg actttttata tatacagaac ctcatgttga tggtgtgcaa acagcataag
     8761 atttaagcta gctttaagat aggttgtcta ttatcaaatg catctactag gagggatgca
     8821 aaatatgaat tttatgaaac gtgcatggaa aagtacaaaa gtaaaatggg gacgttcatt
     8881 gttattgttt gccgtgttca cagccattct tatttttgtg ctagctggcc tcacgattcg
     8941 aagcgctgca gaagaagcag cgaatcaagc acaaaaagaa gttggagcaa cagtgacttt
     9001 aagtgccaat cgagaagctt catttaaaaa acaggaacaa acttcttcaa gcggttctac
     9061 cactgaagaa cgtccagatc caggcagttt ttctcttaca ccagtttcct taacggacgc
     9121 ggaaaaaata gctgaattag ataatgtaaa gagttattcc tttgaaagtt ccgcctcagc
     9181 tatggcaaaa gatggaataa ctgccatcac tagttctgat tcaagtgaag acagttcaga
     9241 aactactgat gcaggcggtg aacctgctgg aggaatgggc gggaatccgc aaatgactca
     9301 agcagacttt caaatcagtg gtgtgtcagc aactgcacaa aatagtaatt tttctgatgg
     9361 aacagcaaaa atcacggatg gtgaaggaat agatgacagc gacaaaggca caaacaatgt
     9421 agtcattgat tctactctag cagaaacaaa tgacctggca gtcggagata ctttcacaat
     9481 cacgagtact gaagatgaag ataccactta tgaaatgacg atcaaaggaa tttatgaatc
     9541 cagcgaaaca agcggcagta tgggtatgaa attcaacttc atgaatccgt cgaatacact
     9601 ttacacttct tacacttttg caaatgaact aaatgggaca tctgacgata acacgataga
     9661 ttctgctatt tacactctat ctgatccaga taaaatggat gagtttctca aagaagctga
     9721 gaagctgatc gacacagata catttagctt acaatcaaat gattccatgt atcagtcaat
     9781 gttggaacct ttaaacaacg tggcaagttt ttctaaaaat gttgttttac tagtgactgt
     9841 agccggtatt atcatactta ctctgatcat tatgattacc attcgggagc gtcggcatga
     9901 gttaggcgtc ttgctatctt taggagaatc cagaagtaaa atcattctcc aattgtttac
     9961 cgaagtggct atttgtatga ttcttgcatt aggagttgct tcgcttagcg gaaacgtcgt
    10021 cgcgaatgcc gtgggacagc agctacttga ccaacagaca gaaaccacga cacaaaacca
    10081 gcaagctcct ggcggtggac aaatgccagg taacagacaa gaacaaggcg gtcaacgcga
    10141 tggtcaacaa ggaaccacga ataatccatt tgctgtttct gatcaagtca gcgaattgga
    10201 aatcaatgtc aaacctgcac aattgggact attagccgga gtagcatttg gaatcagtct
    10261 gttttctgtc tttttagctt ctatagggat attaagatta aacccaagaa aaatcctatt
    10321 aaactaaagg aggaatttga tgttacggac agaacaattg ggattttggt atcaagatcc
    10381 gcaagatgcg ctttataaag atgtagaact gaatttcgaa gctggaaaaa tgtacgctat
    10441 tttaggagca agtggttctg gaaaaacgac ttttctttcg cttatttctg gactagatgc
    10501 accaaaagaa ggaaaggtat actatcaaga tcgttcactg aacaaaatcg ggttaagaag
    10561 ttatcgtaaa aatgatgtct cgattatttt ccaagcttac aacttgcttc cttatttatc
    10621 ggctctagac aacgtcatag cagcaatgga aatcactaag accaagcaag agaattatcg
    10681 acaagttgct ttagatcgac tggctcgtgt aggaattgat gaaatattag caaaaaaaca
    10741 ggtgaccaaa ctttcgggag gtcagcagca gcgagtcgct atcgttcgtg ctatctgctg
    10801 tgaacatcaa ctaatcgtag cggatgagcc tactggaaat ctagatgaaa caacttcaca
    10861 agatatcgtc aaacttttcc aagaaatcgc ccatgaacaa aatcgctgta ttatcatcgt
    10921 gactcatgag attgaagtag caaaaagctg tgatgaagtc tttgaactaa aaaataaaaa
    10981 atttcaaaaa atcgaagttt aaaaaacagg ataatgatca aataaaaaat ccgaaccata
    11041 tctgtctcgc agatatggtt cggatttttt atttgcttga ttcaattagt aataagtggt
    11101 ttttattttt tttcgtcttt tcgagaaaac ttgtctttga cttcgtcgcc taaatttcga
    11161 gctttttctt tgatgtcagc acctagtgat tgtgctttcc cttctgtttc tttgctcttg
    11221 tcgtctgttg ctttgccgta tgcttctttt ccttcaccga ctactttatc tttcatatct
    11281 ttagaacgtc cttttaaatc tgccattgtg cttcctcctc ttagtttgtt tattgatcta
    11341 ccttcagggt aacatcaaca acagatacag acaaacagaa cgctcgtttt ctaaaaaaga
    11401 tagttagagc tgttgattaa aaactttttt cgaaagtccc ccatactttg acttcttttt
    11461 cttggaccat tatttctcct ttagcgataa ctgtatcaat atcaagcgtt tctttatcca
    11521 agatacacag atctgcatca gcaccaattt cgatttttcc ttttttatcc aatttcaata
    11581 tacgtgctgg attactggtt atagctcgta aggcgatttc caaagggata ctttcttttt
    11641 gcacagcttc tttgatccct actagcaatg ccttggcact tcctactcct aaccctagga
    11701 aatgattgtt ttcatcaaaa taaggcaagc ttccttgtcc atctgaggtc atcgtgaaat
    11761 tatctaaaga aacatcttcc tcgatcaatc gtttcagtgc tttgctgaag cgaacttcac
    11821 catctgtctt ctcccaaaaa tcaggatctt cgctagcagt gaagtcaatc gtgccaccac
    11881 gtttggcaaa tgccacgcaa gcttcaaata attctggtgt gcgatttgca tgagtaggca
    11941 aaaattgtgt gatcggaatt tctgtttctt ctacgattcg tgtcaatagc tctagctttc
    12001 tttttcctcc gcctaagtgg acattgatga tcccagcttt tccggataac atgcctccta
    12061 cacgagcatc tgctactgca cgagcgaact cttcaaaact tggctgagaa gaacggtgat
    12121 cggatactgc gatttctccg attccgataa ttttatcaat tgtcaaaaag tctttgatga
    12181 tagaatctgt tactgttttt accggcaatc ggtacgaacc ttcgtataca taagtggaga
    12241 ttccttctgc ttccagacct ttcgctttgc tgatcaacgc agtcatatct ctaccttctc
    12301 cgtctgttcc caaacaaccg acaactgtcg ttacaccagc tgtagtcaat tggctcaatg
    12361 tgacttctgg cgttcgattt tgataaccgc cttctcctcc tccacctaaa atatggaaat
    12421 gacagtcaat gaaacccggg gttagtactt ttccctcacc tgaaagttct tctacttcca
    12481 ctccttcgta gccgccttct agctgttctt ctacagccaa aatcttccca ccggcaatca
    12541 gtacatccat ttttcctaag taatctggtg caaacacttc aatttgtcga atgattttca
    12601 tacatttttc ctctttcttt aagtataact gatgatagga tcttaaaaaa taatccaaac
    12661 gataggatct ttactccttt gattttaccg taaaatgacg gttcttggag tccttatcta
    12721 ctgtttggat tactttttta tttacaggtc tccagtacta ctgcagacct attgcaatgg
    12781 caatcatgat gaaaatagtt cctaaaacaa acaggaatcc ttgcatcttg atttggaatc
    12841 ttgcccattt tgcccattcg atccgtgcaa cacctagcac accaatcaag ctggctgata
    12901 cgggtgtaaa agcgtccata aaacctgaac caagctgata agcaagaact gctacttgtc
    12961 tggatacacc tactaaatct gccagtggag ccatgattgg catagtcaaa gctgcttgtc
    13021 ctgaatttga tgtaacaacc aagttgaaca aactttggaa gatgtacatc gcccaagcac
    13081 caatgacagc tggaacaccg gtcaacgccg tcccgatccc atgcaaaatc gtattcaaag
    13141 ctgaaggaac agatgcatca gatcctccca agacaagaag aatccctttg gccataccta
    13201 ctacgattgc tgtaccagct aaatcagctg caccagattg gaaagaagaa gcgatgtcat
    13261 tgactttcat tccatctaat ttgaaaagaa cagcaatgat tccagcaact aatcccatca
    13321 caaagaattg agaagcgatt tctggaatgt aatagccttt ttgagtcacg ccccaaacga
    13381 tccagacaag gacaactaac atctctaata agatcaattt atgcccaagc atgaattttt
    13441 tattttcatc agatgtcttt ttgatatgag aacggaaata atcatctgat ttgtaagtca
    13501 acgaactttc tggtttttta cggatttttt ctgcatatat catcatataa ccagcggcta
    13561 atgcagtaac aactacccac ataatcaatc ggaatgtcgc accagacaac acggggattc
    13621 cagcaatccc ttgagccacc gctacgctaa acgggctcat ccaagaggtc gcatttccga
    13681 cttgagatgc gacataagtc acggttactg ctacgatcga gtcatatcct aacgcaatga
    13741 caaatggaac catcaccatt gagaatggaa ttacctcttc tgccatcccg aatgtagcgc
    13801 caccgaatga aaaagcaaag aataatagcg gtaaagctaa acgctccagt cccttagttt
    13861 tactgataaa cgcatagata cctgcgtcga tcgctccggt acgcataata ataccaaaag
    13921 cacctccaac aacaaggatc aatgcagcga tccctacagc agatccatac ttatctccag
    13981 atactagtcc ttcaaaaaca aaatttaaga aaccaaagcc gccaaaatca tctgttcccc
    14041 atattttggc tgttttatgc aattttttag aagtatcata gatattttcg ccgtactgat
    14101 cgtaaagcac atcatctgtc aaggagattt catctagttt ttcctgcgta agattttttt
    14161 ctccgtcagc aatgactttt tccaatcctt tttccggaac atccagtttt tcacgttctg
    14221 ctggatgatc ttgcagttct tctaattgat caaacacata cgacttatcc agctcgtaag
    14281 cataacggaa ggaatcttga cgtaaaacag tacgagtact tgtttcgcca tttgcatctt
    14341 tgtattcaat atcttgcgtg ctgaactttc ctgctggaac gacaaaagtc agtatccatg
    14401 caaagatgac tacaccaaaa ataatgacat acgtatgggg tgtcgataat ttagtgaagt
    14461 cgcgtttcgg ttttcctgaa gaatttgttt tcttcaaatt tatttcttcc tttctttttt
    14521 cagtaatttt gatgaataaa aaatggataa tcaaatgaat tatacagtaa aaatgacatt
    14581 tccacatgaa taatttatta gaaaatcact tttttctatt ttgctttttt tctcctatgt
    14641 atgattattt ttttctcttt ccatttatat taagtatttt atttctctgt ttttccttaa
    14701 aattcttttt ttatttttag attagagaaa atctcgtcct gtttttttca ttttacaatc
    14761 attgaaaaat tgaatttcat tgcaaaaaaa ataataaaca cttataaata tccattatct
    14821 atccttcaat ttttgtgtat tttatttcta ttagaaaaag gtatcctgtt ggacaatttt
    14881 gttatatcag gtaaacttca ttgcaataat gataacaaat gtactataat tactttgtaa
    14941 agagttttgg ggaagactct ttcatcaacg tgtattaaga gacaagaaag aatccatatg
    15001 gattctttct tgtctctttt tccactactt tttatttttc tgacactaca tattcttata
    15061 actcatttct cataactgtg aaacaactta taaaaataac aaactttaaa caaaacaagc
    15121 ttaaaatcaa agatgatcca tcttaaaata actaaaacaa aaaaagtagt cgttgttaat
    15181 cctcattaat aatcgttttc tttttttcaa acgctccatt tttatgtgga acattatttt
    15241 tttaaggaac tttgtcaaca tgtggataac tattttccac ttgtgtcctg gactagctgt
    15301 tttgctgtaa aatacaaaac ttgctgcagc aaaaagatcg ttgcaagaga ggctgttccg
    15361 cagatcgctg gatctagatt tggcaaagtc aagactgcat catgtaaatt ggcgtggttg
    15421 tccaaaacca aatcagcaaa ttcaaataat cgcaaaccac tgctatgttg cgatttgata
    15481 cttcgtgaca aatcaaatcc agtaacaatg attaatggat gaccattttc tttgatccac
    15541 tgagctagtt cgatgattgc cgggtttctt ccttcattcg aaagaagaag aaaaatgtct
    15601 tctgatttga cagaaagctg atcaataatt gcctgtcctg caccttctag cgtttcatag
    15661 acacctccgg ctggattttc aatcaatata cttggtacaa gatccggggt ttgatcccaa
    15721 aattcaaatg ctacaccact tagtgtgcgg ctagcatata tctgcaatct accaccttga
    15781 ttaatttgtt tcgcgatcca agtgccagct tgaagcatca gcggctcttc tatccttaat
    15841 ttctcttcca attggtgata atagtcaaaa taacataaac tcatttatct ctcccgccta
    15901 gctatacttg acatgaatag aaacagctgc ctaatctaag gaagtacata aaaaaacagt
    15961 agttagacag taacacatgt ggtctttgct gtttcaaaca caaaaaaggc attgaacgaa
    16021 tacgcccaat accttgacat agcaaataaa acaacgtgca gaccatggaa aatatctaca
    16081 taggggtaga attttcaccc tagattaggt acaataaatt aggtcgatgc actgcattga
    16141 ctatggcaaa atgatcggtc agggtgtatg tgtgtgactg gtcattccct gattcttagc
    16201 gccaactaag ggtcagggag ccttttttta ttcagctgtt tctatctgaa tttattgtaa
    16261 gtaatctctt atccaagtgc aagcaagaaa atacaaaaaa acattggtat gatttatata
    16321 tatataaata acataaaaaa aggaatggct tatcccgata caacaagcat tcctttaaaa
    16381 aagattcttt tatataagtg aaaaaagctt ttttccacca attaaataaa tctctcatct
    16441 caatagttta tccattattt tatctttttt tgcgtatacc tactaaatat taccgtcttc
    16501 ttctcgttct tctactttgt tcgagagaat ctgtactaga aaaagtagtt gtatgtctac
    16561 cttttctgcc tatccgagac tttcttttca tatatgggat ataaatgatt agatacagta
    16621 cagcaaaaaa taaagcaaat acgcaagctt cccaactacc taacgccaat tcaaccatca
    16681 aggtagcaac cccaacggat gctgcatacc agataaaaat cagaaacgtt tctttttttc
    16741 tgaccatgcg aaacatgata aatagactaa taagcaatag tggcaacaca aatatccaat
    16801 tgcttccttc catcagccac ttgagtatat caagcagcga ctgtgcaaca gcgactaatt
    16861 ttcccatagt gaacacacac ctttttttat aattaaaaaa ttcgcctttt tattctacta
    16921 tgaatcttct ggcttggctt tcatttctct tatgtaatca ttttctttta tacaacttaa
    16981 aaaaaaatta aaccattagc ataatatttt ctgaatctat tcacgaaagt ctttttctat
    17041 ctttcgtttt ccacgactca actgatctag agtcaaaaaa ctaaaacgac agttgcgcaa
    17101 atgacgcaca agctgccgct ttaataacaa atagcctttc attctcagca ggccacttat
    17161 ttccagttaa ctttctgttc ttagcttttt actcaactgg ataatatatg cacttaatga
    17221 agtcccaatt tccgaatgtt gaagtccata ttcaatattt gtcttcatat atcctaactt
    17281 atcgcctacg tcgtatcttt ttcctttaaa ctctctcgca tagaccgcct ctgtctggtt
    17341 aagagtctga agtgcatccg ttagctgtat ctcgtttcct gctcctggtt cttgagtttc
    17401 taatatctca aatattttag gagtcagtag ataacgtccg ataatggcta aattacttgg
    17461 tgcttttccc atttcaggtt tttctacaaa cccttttact ctgcaacgac ccttttcgct
    17521 atctgtttta ggatcaataa ttccgtattt agatgtttca ttttctggta cacgcatgac
    17581 ggcaacagcg gaagcttgtg tttcttcata atccatcatc aattgttgag tcaatgggat
    17641 atcatctttc atcaaatcat cccccagcat gacgacaaac ggttcatttc ctataaatgc
    17701 ttttgcttga agcacggcat cccccagtcc tcttggatga gattgacgga tgaagtgaag
    17761 attgacttga gtcgtttctt caactaaagc gagtaattct gttttttcct tttcccgcaa
    17821 attgttttcc aattcgatat ttgcatcaaa gtgatcttca atgggtcttt tttcttttcc
    17881 cgttacgatc aagatgtctt cgattcccga atccaatgct tcttccacaa taaactggat
    17941 cgttggttta tccacgattg gaagcatttc ttttgccatg gcttttgttg ccggcaaaaa
    18001 acgtgttcct agcccagcgg caggaatgac tgcttttttg accttcactt
//
LOCUS       DAZULR010000050        17967 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.051, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000050 DAZULR010000000
VERSION     DAZULR010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17967)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17967)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17967
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.051"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            94..2421
                     /locus_tag="ACG8ZV_002137"
     CDS             94..2421
                     /locus_tag="ACG8ZV_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBG domain-containing protein"
                     /protein_id="HFS4997424.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSATETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
     gene            2418..3332
                     /locus_tag="ACG8ZV_002138"
                     /pseudo
     CDS             2418..3332
                     /locus_tag="ACG8ZV_002138"
                     /inference="COORDINATES: protein motif:HMM:NF027869.4"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
     gene            3405..3920
                     /locus_tag="ACG8ZV_002139"
     CDS             3405..3920
                     /locus_tag="ACG8ZV_002139"
                     /inference="COORDINATES: protein motif:HMM:NF037639.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prealbumin-like fold domain-containing protein"
                     /protein_id="HFS4997425.1"
                     /translation="MDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFT
                     SSKDGTFSVHGLSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEP
                     KANPTNNGKTPVQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKK
                     QQKGNNRREIK"
     gene            4048..5346
                     /locus_tag="ACG8ZV_002140"
     CDS             4048..5346
                     /locus_tag="ACG8ZV_002140"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFS4997426.1"
                     /translation="MHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYP
                     SKDTAVPADATPFASVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLS
                     LPFYNPNSSDPDKPLDTIHLYAKNVIKESNIKIQKAGNFSGVDKLAGAQFQIKNSENQ
                     FVTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVETKAPDGYQLTNPQ
                     KETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNTITVENVQNYGDFHF
                     IKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWSDEVTGSDWEEVKL
                     ISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDDDPTTSDETTIDNQ
                     PKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            5552..6725
                     /locus_tag="ACG8ZV_002141"
                     /pseudo
     CDS             5552..6725
                     /locus_tag="ACG8ZV_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
     gene            complement(6887..7561)
                     /locus_tag="ACG8ZV_002142"
     CDS             complement(6887..7561)
                     /locus_tag="ACG8ZV_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997427.1"
                     /translation="MKKLVALFLVAGSLLSGCGATTSTTQSTSSAQASSSSTTISEST
                     ADSSKEQEQIEKKKEEEKQKAEKAALEKKVTEAESALSQAEANPTKENYATASAAIQA
                     LPENKQELTSRLAAIDSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQQ
                     AAAEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPC
                     SKCYGN"
     gene            7931..8353
                     /locus_tag="ACG8ZV_002143"
     CDS             7931..8353
                     /locus_tag="ACG8ZV_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4997428.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            complement(8519..9712)
                     /locus_tag="ACG8ZV_002144"
     CDS             complement(8519..9712)
                     /locus_tag="ACG8ZV_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4997429.1"
                     /translation="MTTYQRKLLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            9936..10313
                     /locus_tag="ACG8ZV_002145"
     CDS             9936..10313
                     /locus_tag="ACG8ZV_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFS4997430.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKKIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            10301..10639
                     /locus_tag="ACG8ZV_002146"
     CDS             10301..10639
                     /locus_tag="ACG8ZV_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFS4997431.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            10773..11216
                     /locus_tag="ACG8ZV_002147"
     CDS             10773..11216
                     /locus_tag="ACG8ZV_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HFS4997432.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            11478..12293
                     /locus_tag="ACG8ZV_002148"
     CDS             11478..12293
                     /locus_tag="ACG8ZV_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4997433.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            12303..12965
                     /locus_tag="ACG8ZV_002149"
     CDS             12303..12965
                     /locus_tag="ACG8ZV_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFS4997434.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLF
                     AWIVSVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVL
                     RIAFYYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTM
                     DL"
     gene            13170..14834
                     /gene="alsS"
                     /locus_tag="ACG8ZV_002150"
     CDS             13170..14834
                     /gene="alsS"
                     /locus_tag="ACG8ZV_002150"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003984 - acetolactate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0034077 - butanediol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HFS4997435.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAKLTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            14847..15557
                     /gene="budA"
                     /locus_tag="ACG8ZV_002151"
     CDS             14847..15557
                     /gene="budA"
                     /locus_tag="ACG8ZV_002151"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047605 - acetolactate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0045151 - acetoin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HFS4997436.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            15687..16184
                     /locus_tag="ACG8ZV_002152"
     CDS             15687..16184
                     /locus_tag="ACG8ZV_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HFS4997437.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            16369..16629
                     /locus_tag="ACG8ZV_002153"
     CDS             16369..16629
                     /locus_tag="ACG8ZV_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997438.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVIGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(16991..17230)
                     /locus_tag="ACG8ZV_002154"
     CDS             complement(16991..17230)
                     /locus_tag="ACG8ZV_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997439.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            17516..17830
                     /locus_tag="ACG8ZV_002155"
     CDS             17516..17830
                     /locus_tag="ACG8ZV_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997440.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
BASE COUNT         6089 a         3103 c         3539 g         5236 t
ORIGIN      
        1 gccccaaact ttctatacat caataaaata ataaaaatta aatttagaat aacgtgtaaa
       61 ggattatttg atgatttttt attgagagga gggatgaaaa tgattaagaa aactcaaaat
      121 aaaatccaac gtatatgtca aaaacatttt gtttctagac tcaaagctgt atctaaaaga
      181 aaatacttac atcccattat gatttcgatc atcttgattt ttactttctt agggagctta
      241 tcaagtattt atgtaaacgt ttatacagaa acgtcaaatt ttgctaacca aacgacagag
      301 gagacaaata gtccacccta ttctgaaata cagtccatag aaagcaccaa tcagtctagc
      361 aacaacgaga caacctcaac cacatcctcg actcaactga ttgatccgac agaaaaagaa
      421 atcacagcag caaaagcagc aggggagaaa gcttattcag aaacaggtag aagccagaca
      481 tttagtactg ttgcggccac tgcgaatttc aacggacata ccataccaga tggatataca
      541 gtgatatatg ccaaagatgg agtcattgtt gcggttaacg gatcgatgag tgcggataaa
      601 actgcgttac aaggcgtaac caaagcaatc gcttttattg ataaccgtcc agatatccat
      661 aatctgttta ttggctccac agtaaatggt actactatca cattcccaaa aagtatctat
      721 atgggggtgg ctaccgctgg aaatacgatc gattcagtta cacccaatgc ggataaaagt
      781 tattctttta caccctcaac atggggaggg cttcctgccg gaggaggtat gagtactttt
      841 tcaatcggta tacagttagc aaatgatatt ccattcacgg ggtactcgat caaaaatggg
      901 cagatcgttg atggtaaggg aaatgtttca aattttccaa cctatcaagc agcaacggtt
      961 caggtcaatg cgaatcggac aggaactttt tcttatacag tcaatggtgg agcagcaaaa
     1021 atcggaacgt acgggactac attatctgga atccatgtgg gtgacaaagt ggttatcact
     1081 ccaacagcag taacgggcta ttcttttgca caaacaaacg gttctttcac agccctagaa
     1141 agtaacgtcg atacggtgac ctatacaggc aaacaaacac caatcactat taagtatcaa
     1201 gactattttg gacagatgat tgctccttct aaaataatga atcttactta cggaagtgct
     1261 gcacaagacc tgacgactaa tacgcctact atcaacggat atacctttac agctgtttca
     1321 gcgacagaaa caaagaacca atcagcaatg agtgttttag ctagtttaga tacaaatgga
     1381 aatgtaatcg taaaggacgc aaatggaaaa cagatttctg aagtcatcct atattataag
     1441 acaaatgcaa cagtatcaat caatgcaaat ggcagtaagt actatgatgg tctttctgtt
     1501 gtaccgatcg ttaaatatgc ctttaatgat aaaacagaat caacatccct tttaaacaat
     1561 gatctcagta ttgatcaaat cacatggaat ccaactgatt tcaaagcgat gaatgaaaag
     1621 ggagttgaag taactgcgcc tactgaaatt ggaacctata cgtcttggca attgacaaaa
     1681 agcggactag ctaaactagc tgccagaaca aactatttat ttactatcgt gcagacatct
     1741 gatgtctata cgattaagca aatcagcggt gcggtagagc tcagtggcag taagacatat
     1801 gatggaaaag caggtgtccc gtcaatccat gtcaagctag cagagggtgt cactagttcg
     1861 cttactccag tacaagtggc acttagcagt atggattaca cagcagatgc acaatcagca
     1921 aaaaatatgg ttaatgctgg cagctataca attaaactaa cgaatagcgg aatagacaaa
     1981 gtcaaagcag caaatcccaa gttgtcattt actgatatag ccaacacatc aggaacttat
     2041 accatctata aagctaacgc agtgattact gtcgatgacg ctgcctttaa ttatgatgcc
     2101 caaagtcact cgatttcggt tggaaatctc cacgttaccg gtgttgtctt aggcgaatca
     2161 ttggattata ccctaacagt taacagccgg acagatattg gatcacaaat agtaacgatt
     2221 agtttaggcg aaggaagtgt aaacaataat tatacgatta tcgcaacaga taccgctaag
     2281 ttgacgatca atccgactct cttgcttcct tcgacaggtg ggataggtct actgcccttt
     2341 gtctttttag gactgatctt tattttttct ggcttctttt attttatcca tcgtaagaaa
     2401 aaagcaggtg aacagcgatg aaaaaaacaa aaaatgtacg tgtggatata tttgctgttc
     2461 tcttttttat cctactggtc ttttttatag gttctccgac tgtgtcagct agagaatcac
     2521 ctattacatt tactttgcat aatcgaatgt tcgaaagcga taagatgcca agtatcagtc
     2581 aaaacgacgg aataaatatc ccggataact ttcaaggagt aaaagggttg aacggcgtta
     2641 ctttcgctat atatgatgtc tcggatgaat tttacaagct gcggtcagaa ggaagtagtg
     2701 tggaagacgc acaaagaaaa ctagcacaaa aaagtgatag tgaaaaaata ctggcagaaa
     2761 atgtgacaaa aacagtagac gaggaagagg gcattgcttc ttttagtgca tcggacaaag
     2821 atgagcaagg tcgtgacgct gtttaccgat ttgcggaaat aaagacttca gattaagtaa
     2881 aagaaaaatc agcaccattt gtcgttgtgc ttcctgtgac agattcatct aatcataaat
     2941 tgacgaccat ccacttgtat ccaaagagcg aacaaaaaat acctgctgca ctcacattaa
     3001 caaaaacagt agagaataag cagacagatt ttgcagatgg ggataaagtt ccttatctca
     3061 tcaccgtaac aattcctgag aacatcaacg agataggaac ctatacgatc aaagatacag
     3121 ctgatcctca gttatggcta gaaccagaaa cgatcgattt tttgattggt ggagacaaga
     3181 ttcatacatt tcacacacaa aaaacaaaac atggttttgt cttatcagat tctggaaaag
     3241 atcttagttc gtttgctggg aaaaaattaa cgatccgtta ccaaatgaca ttgaaagaaa
     3301 acagtgaaaa aacgacattt gataacgatg tacgtttgac gactgacaat caaacagtag
     3361 aaacacatct tgccatccaa acaggaggca aacaatttgt caaagtggat cggcaaacga
     3421 aacaaaaact agcagatgct caatttctag tcaaaaaaaa tgaccaatac ttagcgcaag
     3481 aaaacgggat aaatcattgg gtagccaaag atgattcaag agcaacgatt tttacttcca
     3541 gtaaagatgg aacattttct gtccatggat tgtcttttgg aagttacgaa ctagtggaga
     3601 ttaaaccgcc taaaggatat atattgagtc aatcaaccat tctctttgaa gttgaaaaag
     3661 gcagttatga tccgcttcat cctataccat tggaaatcat caacgaacca aaagcaaatc
     3721 cgacgaataa tggaaaaacg ccagttcaga tgcagacaaa tggtccatca aatgaaaaaa
     3781 atggaggaag ctttccaaaa acaagcgaag agatgcttgg aggtttctca attttagggt
     3841 tgttgctagt cctttcaaca gggacagctt ggttttataa aaaacaacaa aaaggaaaca
     3901 ataggaggga aataaaatga aaaacatcaa aacaaaaata tggacgtttt taggaactgc
     3961 tatcatgctg cttcctttcg ttctcggcct aggaactgca gaggtttcta ggccgtatca
     4021 cctacaccag aaaatgttac ggttaatttg cataaattga aattcacttc agcaccagaa
     4081 aatcaaataa acaacggaac ggaattgaca tttccgaata gcgaaccgtt gaacggcgtt
     4141 gaattcaacg tatatgacat cactgctacg tactatccaa gtaaagacac agcagttcca
     4201 gcagacgcta cacccttcgc aagtgtaacg acttctggtg aaggattagc taacctgact
     4261 cttccaggta aatctgatgg gaaagatgct gtatacgtct ttgtagaaac accaaagccc
     4321 ggtgtcgaaa cgtcgccaaa tatcgtgtta agcttaccct tttataaccc gaattcatca
     4381 gaccctgaca aacctttaga cacgattcac ctatatgcta aaaatgtcat caaagaaagc
     4441 aatatcaaaa tccagaaagc tgggaacttt tcaggggtag ataagttagc aggggcgcaa
     4501 ttccagatca aaaattcaga gaatcaattc gtgaccggtt ttgatgaaaa cactggtgtc
     4561 gctctctatg atcctgctga gtcagcgttg acattcacaa ctgatactga aggatccatc
     4621 agtgtcaatg gattaataga cggcaattat actttagttg aaacaaaagc accagatggt
     4681 tatcaattaa ccaatccaca aaaagaaact acttttatag taaaaaacgg aaaattgcaa
     4741 caaacaaccg gtatcatcca tggcgcagat gaagccaatc ttgggaatcc aaacggtgta
     4801 gtcaatcggg aaaatacaac tacggataac acgattactg tagaaaatgt ccaaaactac
     4861 ggtgatttcc acttcatcaa acaagatgtg aacacgcaag aaaaattagc cgatgcagaa
     4921 ttttctattc taagagcaaa agatccaact gttaaattaa tgaaaaaaat agcaaatctt
     4981 gcctcaggag aatacccata tgcttggtca gatgaagtca caggttctga ctgggaagaa
     5041 gtgaaattga tttctgattc agaagggaaa ttttcaatcg aagggctgaa acaaggggca
     5101 tactgccttc aagaaacaaa agcaccagaa ggctacgcat tacctaagaa tgaagctgcg
     5161 tacactgaat ttacagtaga tgatgatcca acaacttctg atgaaacaac gatcgataac
     5221 caacctaaag gaatcttgcc ttcaactggt ggtatgggga tcatcgtatt catcttggta
     5281 ggtactgctt tagttggagg agcagtgatc tacttcaaaa aacgccatca agaaacagaa
     5341 gcttaaacta ttggaaacaa aaatcatacg ataaataaac gatagtgatt caaatgggga
     5401 gaaaggttgt gacaagtggt cggtctcttg gtattcgctc aacaaacggc aaaataggag
     5461 gaactatttt gccgtttgtt gagcgaatac tcaggtcaag gcgctgattt cacaacctct
     5521 tcatatacat attagaaaat aggtggacat gatgaataaa agcagaataa gaatactgga
     5581 catcttcatg gcaatcattt tagtcgttgg gatcgggatc ttttcttatc cttttgtaga
     5641 agattcactg aatgattttc ttgcccagca aatgatcatc cattatcaaa agcaagcatc
     5701 gaataagaat tcagaggaaa taaaaaaaac agcaggaaaa aatgacaaag aaaaaccaac
     5761 agttggcaga gcaaaacgta tcaccaggga taggcagttt caaccaagca gttgatgcaa
     5821 aagcattaaa agatttacct agtaatgcct tttttatgga acatatgctt ggagtcatcg
     5881 aaatcccaaa aatcaatgtc agcttaccta tattcgatca gacaacggaa atatttttgc
     5941 aaaaaggaac gtcattattg gaagaaagtt cttatccgac tggcgggaaa aacacccatg
     6001 ccgttctttc tgggcatcgt ggactcccag aagcaaaatt atttacagat ttgcctaagt
     6061 tgaaaaaagg agaccagttt ttcatccaga tcaatggaaa gacattggcg tatcaagtag
     6121 aaaaaatcca agtggtctta cctgatgaag tagattcttt gggtatccaa aaaggcagag
     6181 atctcgtgac tttgcttacc tgtactcctt atatggtcaa tacacatcga ctgcttgtga
     6241 cggggcatcg tattccttat caagcaaaag aggcaaaaaa agcgatccaa ggaattgatc
     6301 aatggaaaaa atggaaattt tttatttggt ttatcggtat actacttgga tcaatcggct
     6361 tagtttggct actcatcgct tatttagatt ctttggccat cgctaagcga aactatcctt
     6421 tatcttttta tgtaaagaac acaaacggac gaccaatcga aggaatggtc ttttctgtaa
     6481 aaacgctcaa cggcaaacac tatattacta gagaaaaagt tccatttgtg aaagcttctg
     6541 atgaatacgg actagtgaga ttttctgatt taaaaggcag gaactatcgc ttgcaacatg
     6601 aggagctcct gcttaaaatc catgtaaaac ataaacattc gaaacagttt tcaatgaaat
     6661 tgaaaaaagg aagatataaa ctgcgaaaag aaaaagaggt gtactatttg attgagaaag
     6721 aatgaatgaa gatgtccaaa aaagcagagg gaacagacta aatgaaaaaa gagagaagct
     6781 gacgaaatgg acgtgtaaac tgctattttt ggtttactat ctggaacgcc agcttctatt
     6841 tttttatgtt tcagaagaat tttattatta tagtataact tttgaattag tttccataac
     6901 atttggagca aggggttaaa ccacgagctt gagcttcgct taaagtggca ggggtatacg
     6961 taccatttcc acatttatgt gtatggtatt ttgaaccggt cggtgtgaca tagacagttt
     7021 gttcattatt ttgctcagga gctgcggctt gtgcctgctg agaggcctgt tcagctgctg
     7081 cttgctgtcg cgcctgttct gcttgttgct gtgcgattgc ttcttgttgc gcttgttctg
     7141 cttgttgtcg tgcaatttct tcttgctttt tccgttcttc ttctgcttct tttgctttga
     7201 ttgtggaatc aattgcagca agacggcttg tcaactcttg tttgttttca ggtagcgctt
     7261 ggatagctgc tgaagcagtt gcatagtttt cttttgtagg atttgcttca gcttgtgaca
     7321 aagcagattc cgcttctgtc actttttttt ctagtgcagc tttttccgct ttttgtttct
     7381 cttcttcttt tttcttttca atttgttctt gttctttcga tgaatctgcc gtactttcgg
     7441 agatcgtggt actgctgctg gaagcctgag ctgaacttgt gctttgagta gtagacgtag
     7501 tagcaccaca cccactcaac aaacttcctg cgaccaaaaa caatgcaact aattttttca
     7561 ctaaatttcc tccttaagta aaaaacaacc gttttcaata aatgtccttt tcaattgttt
     7621 acttacttgt tataataatt gtgttatgaa tagtgattga ggaaacttaa tctaatcccg
     7681 ttttgataca cgggattttt tgctatagtt ctgttattaa gtatgcaata ataaaatatg
     7741 tacgttattt tattattaga ttattgacat ttatataata aacgattaaa tgattcatat
     7801 caatagaata cttaggaaaa aaagagaaat aataacaggt ttatgcacta ttgacggtgt
     7861 gacaatatga tatttgtatc cgtttttttc ttgtatgtag tatagtaaag tagatacagg
     7921 aggagaaaat atgcagactt ttttaacaaa agtttctcaa aagaaaatta aaatgattca
     7981 tttactgctt gaaacagaac gttggtgttc aatagaagaa ctacaaaacg aattgaaggt
     8041 atcaagtaag tctatcttga attatctaac agatttagaa gaattgttcc aaaaatatcc
     8101 tgataaggtc attttgaaga atgagaataa tcggcgcttt tctatggaaa agcaggagaa
     8161 cttcccaatc tacattattt atcttcattt ctacagaaaa tcatataatt atcatttgat
     8221 tgaattcatg tatcaacatc ctgagaaaaa tttggaagat tatgcagacg ctcaatatac
     8281 gagtgtatcc acagtttttc gttatgctaa gttattagta aagtactttg aaatgacgga
     8341 cgtcaaagaa tagtagccgc cagatagaag gaaattagca gttgaaaaag ctgccctgca
     8401 tcaagtaata cgaccagcca aacggaaaca gtgtctcatg tttttgattt ggctggtctt
     8461 attaccgcag atgcaagctt ttgccacacc tctttcttgt catttacaga ctcaactatc
     8521 aatgctgcaa gctttccctt aatgctgtaa caccagtaag agttgtcaag accagcagac
     8581 tgactaggta aataccgctc aaaaacaaga ttacggcagt taaactataa tgatccatca
     8641 agaaaccgat gacgatagaa gaaaaaccac caacagctcg tccaaggttc ataatgaaat
     8701 tattcgccgt cgcgcggatt tctgttggat acaaactact aatcactgcg ccatatccac
     8761 catacatgcc attgataaag tagccgacta tcacagcggc tgctaccaaa ctccactggc
     8821 tatgggctaa cacaagtaga tagacagata aggatgaaca aattaaaaac aaagaaaagg
     8881 ctagtttagg ccccaattta tccatgatta tgccaaaagt catcatcccc aaagacatgc
     8941 ctaaaatagt actgaccatc cacaatgaag acccagaaac cgaaagccct aatcgatttt
     9001 gcataattga aggcagccaa ttcattaacc caaaatagcc ggcaatttgg acagttacca
     9061 tgatactaag gccacatgtt tgccaagcaa gatgttttga ttcaaacagt ctgctaagtt
     9121 tggttttctt ttcggcagat tgtacagatt tgaattcctt tggttcagtc aagccgcgac
     9181 gaatgaacaa gaccatcaac accggcagta cacctacgac atacaacatc ttccaaccaa
     9241 acgttggaat gatcacagca gctaaaatcg cagccaaagc cgcaccgacc tgcgcaccaa
     9301 taccagcaac cgaagaagct cgtccaattt gtttttttga aaaactttcg gaaatcaagg
     9361 acatacacgc cccgtattct cctcccgctc ctacacctgc gataaagcga aagagataaa
     9421 ccaagtagat gtttgaagca aaatacatca ataaagaagc aatcgaaaac agaaggaccg
     9481 tttgagaaaa tactttcaca cgtccatatt tatcagctat gatgccaaaa aaaatacctc
     9541 caatgagcat ccccaaatta gtgatcgttg aaatgaaacc cgcttgcgta ccactaatat
     9601 gaaaagaagt aatcattgaa gataatgaaa aagctaaaaa cataatatcc atattctcta
     9661 aagcaattcc cgccgatgtc gataataata actttcgctg atacgttgtc atttttatac
     9721 cccttttcct aaaatttccc taaattgtta aaagtatatc caaaaaagaa taaaaaaaca
     9781 agactttttt atttgaaata atacacaaac aaccgatata gataatccag cttagtttta
     9841 atagaaatga gtattgactt ggagtacact taaagttgta gaataaataa aatacataag
     9901 taaagtggca agaaattaag agaaagagtg atcagatgaa tatcaaacaa gtcagtgaag
     9961 aaaagggcat ttcggccgat acattgcgct attatgaacg aatcgggttg attccaccag
    10021 ttaatcggac aaaaggcgga atccgtgatt atacagaaga agacctaaaa tgggtcgact
    10081 ttacgatctg tatgcgaaat gccggattat cgatcgagtc tttgattgaa tatattcgcc
    10141 tatctagcga aggagaagca actgtatttg agcggcgtaa gcttttgatt gaagaaagtg
    10201 aacttttgac gaaaaaaatt gctgaaatgc aagaatgttt ggaacgttta caaggaaaaa
    10261 tcaagaaata tgatcgtgtg ttatctagaa ataaaatgga atgtatcaag taaaaaaatc
    10321 aaggagcatc gctatggagt tacgcttact aaaatatttt tggacaattg cagaagaagg
    10381 aacaatctct caagccgcag aagttctaca tcttacacaa ccaaccttaa gccgacaact
    10441 gaaggagtta gaagaggaac taggaacaga actgtttgta cgcgaaaacc gcaaaatgat
    10501 cttgacagaa gcaggttatt ttctaaaaaa gccgagcaga agaaatttta gatttaacga
    10561 atcaaaccac tcaagaattc gagaacagaa aaaaacaatt attcagcggc cgatttacga
    10621 tcggctgtgt ggaagctgat aattcgaata cattggcact attactagaa aagttgatcc
    10681 gtgattatcc cagcgttcaa tttcatatcc acagcggaac aagtgatgat atcacggagt
    10741 gactagaaaa aagcctgtta gatttagcga ttttgctaga tccagtagat acagagaaat
    10801 acgaaacgat tttgttacca agaaaggaaa aatggggatt gctcatttta gaaaattctg
    10861 ttttagcaaa aaaagacgtg ataacaaaag aagactttgc gaatgtacct cttttgatct
    10921 caaagcgtcc agaaatacag cgaatgtttg ctgactggtt aggcataaaa aaggagcagt
    10981 tgctgatcac aggaacgtac aatttgattt tcaatgtatt tgcgctaatt gagaatcagg
    11041 taggtgctgc tttagtcata gaaggtgctg taagtcatct ttcaaagcga gtgacattcg
    11101 ttccgcttga cccaatgatt gaaacgaact gcatgctagt ctggaaaaag aatcggattt
    11161 tatcacctgt agtcaatgaa ttgattcacc gtttcaaaga agcttttgaa cagtaataag
    11221 tatctctaat cgaagaaatt tcaatacaaa agcgagacgt atgacagtct tgcttttgta
    11281 ttttttcatt tttaaatcaa aaaaaataaa gagatttaca taacttgtta aataagcgct
    11341 tacaaacata agaagaacgg aaatgaatca gctataataa ccgttgttct ggattgtaat
    11401 cattacaaag aaatgaagat tataactttg gaggtgttcg aaatgaaaga aaaaaagcaa
    11461 aaattcgttc aaaaaacatg ccctttattc aatggttggg tatgattctg ctgattgtat
    11521 tagctttatt gacgatcatt ccttttttat ggatggtttc tgcttcattc aaagcaaata
    11581 atgaagtgtt cacgattccg attcaatgga tccctaaaac ttggcattta gagaattatc
    11641 tggttatttg gtctcgtatt cctttagtga cattttttaa gaatacagct tttttaagcg
    11701 ttgtgatcac gttgattcag ttgtttactt ctagttttgc tgcttacggg ttttctaaac
    11761 taaattttaa agggcgcgat attttatttt tagcatatat cggcacgatt gctgtccctt
    11821 ggcagtctta tatgatcccg cagttcatta tgatgagaaa agtgggttta acatatacgt
    11881 tgtggtcgtt ggtgctatta caagcgttca atgcttttgg tgtgttcttg ttgaagcaat
    11941 actacagtag tatcccagat tctttatgtg agagtgcgcg gatcgatggc ttatcagagt
    12001 ggggaatcta tcgcaagatc attttacctc ttacaaaacc ggcgattgcc agtttgacga
    12061 tcatcacatt cgttaataca tggaacgatt atatggggcc attcatttat ttgtcttcta
    12121 cggaaaataa aacaatccag ttagggttga aaatgtttat tgggctattt gatgcagagt
    12181 acgcattaat catggctgcc tcagttgttt ctgttcttcc tgttgctttt atatttttag
    12241 cgatgcaaaa atattttgta gaagggatcg cttcatcagg aatgaaggaa taggaggtga
    12301 ttatgaaaga gcagcgtttt gacaaaaatg tttatatgga attcttttat tggttgtatc
    12361 aatcattggc aagtagcctt tgtttttggt gtgtcaatat cttgtatata gcagctgcgt
    12421 tccttttgtc gatagatgga aggaatgtct tttcctttat tttttcttta ctttttattg
    12481 gtccaggttg catcgtgatg ataggtatga cagaagaatt agcaaaagaa aaaagttttt
    12541 caccagtacg tttgttcata aagacgtttc gccaattttg gctaaaggga tttttttatt
    12601 ggctatttgc ttggatagtt agtgtgataa tgatttttga ttgtttcttt tttatacgtt
    12661 tttcttatgg aaaatggttg attccgttgt ttgttttact tgcttgttta tcagtttcct
    12721 ttagcatcaa ctactggtat tttcaggtga gaaatccagc gtcgaaacca aatcaagttc
    12781 tacggatagc gttctactat acgttgaaaa aatggtatgt gagtttacta gattttttac
    12841 tattgacaag tttgtttctc ttctttttcg taaagcccca atggtgtatt ctactaggtc
    12901 cttctatcgt atttggtttg atttacttca acaatcgtaa attgatgaga actatggatc
    12961 tgtagacttt ataaattgaa actttcaatt aagaatgaca gtttttatgt aaaaactgtc
    13021 attctttttc attttttgaa acatatggct aaacaaatga aataaaacgt gctatacttt
    13081 tgaatgaaac aggtttagaa actgtatcaa ttatttgtga ttatttctaa ctaataatta
    13141 aaaataaagc ataaaaagga cgatgttcaa tggacgaaaa aatgaaacaa ggttcgaaat
    13201 ctgtagtaga aagtttgatt aatcatcatg ttgattatgt attcggtata ccaggtgcaa
    13261 aaatcgatgg tgtatttaat gaattagagg atcaaggtcc tgaattaatc gtgactcgtc
    13321 acgaacaaaa tgctgcattt atggcacaag caatcggacg tattacagga gagccaggag
    13381 tagttatcgc aacaagtggt cctggtgcta gtaacttagc tacaggtttg gtaacagcga
    13441 cagcagaagg tgacccagtt ttagcaattg ccggacaagt aaaacgaagc gatctattga
    13501 agttgaccca tcaaagcatg gataatgcag cactgttcca gccaatcaca aaatacagtg
    13561 cagaaatcca agatccagaa acaatttcag aagtgattgc caatgcttat cgtatggcta
    13621 agagttcaaa aaaaggcgcg agctttatca gtatcccgca agatgtagtg gatgcacctg
    13681 tccaagggaa tgtcatcaag ccattgagcg atcctaaatt aggttctgct tctgcagatg
    13741 atatccgtta cctagctgaa cgcattagag aagcaaaact accggtacta ttagtaggta
    13801 tgcgaggatc aagtgaaaaa gaaacgttag ccatcaggca attagttgga aagacagcat
    13861 tgcctgttgt agagacattc caagcagctg gagtgatctc acgtgaatta gaagcgcatt
    13921 tctttggtcg tgtgggttta tttagaaacc aaccaggaga tatgcttttg aaacgaagtg
    13981 atctagttat tgctattggc tatgatccaa tcgaatatga agcaagaaac tggaatgcgg
    14041 aaaaagatgc gcggatcatt gtgatcgatg aagcgccagc tgaaatcgat ccttttatgc
    14101 agcctgaaag agaattgatc ggtgatatct cagccactct tgatttattg acaggttcat
    14161 tagagcctca acaagtgtca gaagatgcaa aagaatattt agcatctctt caagcaaaat
    14221 taacggagcg ggacattgtt caatcaaaag gagaagcagg tatcttgcat cctttagaag
    14281 ttattaacac gcttcagtca aaagtaacag atgatatgac tgttaccgta gatgtaggta
    14341 gtcattatat ttggatggca cgccacttta gaagttatga acctcgtcat ttgttattca
    14401 gtaatggtat gcaaacgctt ggtgttgcat tgccatgggc gatttctgct gcattggtgc
    14461 gtccaaatac acagatcgta tcagtttccg gcgatggggg atttttattc tctgcccagg
    14521 atttagaaac ggcggtacgt aaaaaattga atatcgttca tttgatttgg aatgatggac
    14581 actacaatat ggtagagttc caagaaaaaa tgaaatatca gcgggcgtca ggtgtagact
    14641 ttggtccagt tgattttgtg aaatatgcag aagcttttgg cgctaaagga atccgagcta
    14701 caagtgtaga ggaattagaa aaagctttag aagaaggatt tgcgacagaa ggacccgtaa
    14761 ttattgatat tccgattgat taccgtgata atgagaaatt gggagaaaca atcttaccag
    14821 atcaattcta ttaaggaagt gtcgacatga ctgaaaaaat cttataccag cacgggacat
    14881 taggagcttt gatggccggc ttgatggatg gaacagaaac gattgctcat atattagaaa
    14941 aaggaactct gggattggga acattgcatg ggcttgatgg tgaagtcatc tttttagatg
    15001 gcgtagctta tcaaggaaga tcagatggct cagttgccca attagatgga agtgaactta
    15061 ccccctatgc agcaattaca gattttacgc cagatactag tttttctgtc tcaaaaactg
    15121 cagatggaga acaattgaaa aaagacatat tagtaagaga agccggggaa aacctatttt
    15181 tggcagtgaa gataactgga ttattcaaaa atatgcacat ccgtatcatg ccgaagcaag
    15241 aaaaacctta cagaagacta gcaaaaattt cagagtctca accagaattc caacaaagca
    15301 atgtccaagg aacattagtc gggttcttta cgcctgaatt attccaagga gttgctgcag
    15361 cgggatttca cctgcatttt atcgatgata cacatacatt tggcggacat gtaatggatt
    15421 ttgaagtggc tgaaggaaaa gttgagatta gccgcatctc gtcccttgta cagcattttc
    15481 cagttgatga tccgactttt gttcacgaaa cgattgatta tgctgattta gcagcagaaa
    15541 tccaacaagc agaatagaaa aagacagcga gatgcgttca aggtgattaa cctgacgtat
    15601 ctcgtttttt tgaggagaaa acctagcgtt tacaaaaaaa ctgagctata atcttctcca
    15661 tagatcaaaa aggagcggtt tttatcatgt ggacagaaaa acagaaaaaa gatgcatacg
    15721 aaattttatt attacagcaa caaggattat tagaagcaga agataactgg ttagcaaatt
    15781 tagcaaattc atctgcattg ttgaatgaga ctttgcctga gactgtcttt gcaggatatt
    15841 atttattcga tggtaatgaa ttgattttag gaccgttcca agggcgagtt tcttgcacac
    15901 gtatcaagat gggaaaagga gtttgtggag aatcagctga aaaacaagaa acattgatcg
    15961 ttgatgatgt caaaacccat gcaaattaca tttcctgcga ttcagccgca caatcagaaa
    16021 tcgtagtgcc aatggtaaaa gaaggtaatt taatcggtgt tttagatatc gattgcggag
    16081 taacgaaagg gtatgatgaa atcgatcaag catttctaga aaaatatgta gatcttttat
    16141 tagcaaattt taatataaat gctttttcat ttattaataa ctaaaatcgt ctattgaaac
    16201 aaaaaagaag agaaatcaag aataaaaaga gccggaaaga cagtgggcat ttctgttttt
    16261 cggttttttt atttttttat aaaatcacaa gtgttattga ttttcataat catattttaa
    16321 tgttattatc attttaaata atgaaaaaac attaaggatg gatgaaatat gaataacgaa
    16381 actatcattt taggaaaaaa atatatttgc caacctattg gcttgaaaca aaaagtgatt
    16441 ggagaagtaa tcagtaaatt agaaaattgt gttgtgatct gcgtagacga atatcatgac
    16501 gtcgatcgca atgaaatatt agaaaaatgc ggaaaagtag tggcaaaata tactcacgtt
    16561 tatgagttgg aaacaacaga atatctatat aactatagca acaaatatga acatacttta
    16621 gtttcataaa gatttaaata aagtgccttc aaaagcgaga agaccaagct tttgaaggca
    16681 ctttatttag ttggcagtga ttgttcatga tttttgattt attcaaaagg ttcgcctaga
    16741 gaatctgtct ctgtaacgag gcctggtgga gaaactcgat aaaaacctat actgccagaa
    16801 ctgtcctatt ttcggataga caaactagta gttttaaaaa gatcatccga tccaatcatt
    16861 tcaaaaaatg caaaactgat atcaggatca tttagctcag gcttgttatc gtaaagcatt
    16921 tgtaaaggtt gcatttagtt aggagtaaac gcgaaactat catcattatt tgctgaagaa
    16981 gatgaagaag ctaattcaga gtttgtttga aataaaggag acgtgctgac agtttcttta
    17041 ccctgttttt tgcagaggta gaaactttta tatcggaagt ttctaccgga gaatttttct
    17101 catttgtaga aattgttgaa tcgatactat tcgaaatttg cgtatctgaa ggtatgttct
    17161 ttgatgcaga agtcccacaa gcagtaagta acaataaatt tgataaactg ataaacagaa
    17221 ttcttttcat tatgtacaca ctccttatag tatcgtttag catacaccta tgctcagtat
    17281 taggcaaaat caatgcaaaa ctatcaagtc ttttatagta tctattagtc ttagtaatac
    17341 atatatggag agggtgatat cccagttcaa accagataca ttggttacca tctgtattaa
    17401 cgattatgcc tctaaacgct ttttttatga aaaaatttat aagtgaaaac gtaggtatga
    17461 tattatctag aggtaatttt tttgggtatt taaatagttg ctaggaggat agcttttgga
    17521 tttttacagt aattttatct taataatagc aatattatta cttctaaata tttggttttt
    17581 tgataagagt agaaatgcag ggataggttt tagaaccaaa cgaagtacgt cttctgaaaa
    17641 aaagtgggta tattcacaga ctatttttta cggaggggtt atttcaatca gtttactttc
    17701 ttcaacactt tattctttta atgttataga cgtttccatg tcaaatttta tatctattat
    17761 tggaatcctt atttctgcaa ttattacaca actacttctt gtgtttgaag agaagtcaaa
    17821 aaataattaa agcaattatg ccttttagta caggaattat tacttcttac aaatgtatag
    17881 cgaatgtgaa gcctgctgtt ttaattgttc tagaaaaact tttgagtgaa caattatttt
    17941 atgttaggat gaattaattt ctctaga
//
LOCUS       DAZULR010000051        17170 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.052, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000051 DAZULR010000000
VERSION     DAZULR010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17170
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.052"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(42..851)
                     /locus_tag="ACG8ZV_002156"
     CDS             complement(42..851)
                     /locus_tag="ACG8ZV_002156"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFS4997441.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
     gene            1144..2580
                     /locus_tag="ACG8ZV_002157"
     CDS             1144..2580
                     /locus_tag="ACG8ZV_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HFS4997442.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            2750..3946
                     /locus_tag="ACG8ZV_002158"
     CDS             2750..3946
                     /locus_tag="ACG8ZV_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HFS4997443.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(4008..4193)
                     /locus_tag="ACG8ZV_002159"
     CDS             complement(4008..4193)
                     /locus_tag="ACG8ZV_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HFS4997444.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            4424..7738
                     /gene="dnaE"
                     /locus_tag="ACG8ZV_002160"
     CDS             4424..7738
                     /gene="dnaE"
                     /locus_tag="ACG8ZV_002160"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HFS4997445.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KRQLIYLLGEDNVVFK"
     gene            7906..8868
                     /gene="pfkA"
                     /locus_tag="ACG8ZV_002161"
     CDS             7906..8868
                     /gene="pfkA"
                     /locus_tag="ACG8ZV_002161"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HFS4997446.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            8942..10726
                     /gene="pyk"
                     /locus_tag="ACG8ZV_002162"
     CDS             8942..10726
                     /gene="pyk"
                     /locus_tag="ACG8ZV_002162"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HFS4997447.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(10761..11663)
                     /locus_tag="ACG8ZV_002163"
     CDS             complement(10761..11663)
                     /locus_tag="ACG8ZV_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HFS4997448.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            11849..12418
                     /locus_tag="ACG8ZV_002164"
     CDS             11849..12418
                     /locus_tag="ACG8ZV_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HFS4997449.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            12476..12655
                     /gene="rpmF"
                     /locus_tag="ACG8ZV_002165"
     CDS             12476..12655
                     /gene="rpmF"
                     /locus_tag="ACG8ZV_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HFS4997450.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            12825..14246
                     /gene="gndA"
                     /locus_tag="ACG8ZV_002166"
     CDS             12825..14246
                     /gene="gndA"
                     /locus_tag="ACG8ZV_002166"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HFS4997451.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPFLEQIS
                     AKAEDEAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
     gene            14439..15125
                     /locus_tag="ACG8ZV_002167"
     CDS             14439..15125
                     /locus_tag="ACG8ZV_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFS4997452.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            15122..16627
                     /locus_tag="ACG8ZV_002168"
     CDS             15122..16627
                     /locus_tag="ACG8ZV_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFS4997453.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
BASE COUNT         5555 a         2980 c         3594 g         5041 t
ORIGIN      
        1 aaaattgtca caacctcttt tttgtggaat ctaattctct attatagttt aagtagtttt
       61 tccagataaa cagctaaacc gtcttcctga ttgctcaaag gagtgacatc atttgcaatg
      121 cctttgagtt ggtcagtacc gttagccata gctactcccc aacctgcata atccaacaat
      181 tccaaatcat tatgctcgtc accaaaggca atgacgtctt tttgatcgat agacaggtag
      241 ttagcaatct cttgcacgcc ttttgctttt tggattcctt ttgaaacaat ctctaagatg
      301 gcagtaggtc caccccatgt ccgaacatcg acataactgc caaattgacg tgttaattca
      361 gcagatacag ctcctgcaaa acgtttgtct gttcggacaa gcaaagatgt aggatttgtc
      421 gtcaaatttt taggagaaag caaattcttc tctcctggac gagaagaagc aaaaattttt
      481 tcatcaaaga aatcaaaact gtcaataaaa aaagtatcac gattttcagc agcgataaaa
      541 tctaaattta gctgcttttt ttgcgataag atttcaaaag cgatttcacg attgatcaac
      601 gtttctcttt caccatccca gtgctgatta gggatgtgta ctaatgcgcc gttaaaatta
      661 accatcggtg ttgttaattc taattgttgg taaaactgat ggctcattcg gaatgggcgt
      721 cctgtagcaa tactgacatg atgaccggca ttgattgctt tttttagagt ctcttttgtt
      781 ttagatgtaa tcatcgaatc ttgattgagg gtagttccgt ccagatcgat ggcaattaat
      841 tttttattca ataagggtcc ttccttcctc aactagcatt tgttttagtc tagcatattt
      901 taggtaatta acaagagcaa tcagctattc ctaacaaaaa ctacagttat ggctatataa
      961 atagctaaac ataagctaaa cacgaacgtt aagtattatt ttcgcttttt ttgttaaaaa
     1021 aacgttgaaa agcgaatgaa acgtctatat aatttgaaat tgttcgatgg atttgcccta
     1081 ttttacttat tttttattat tatagttttc catcagaaaa aaattcaggg agtggaactt
     1141 tttatggaaa agtttttcgg tttaaagaaa aacaatacaa atgtatcaac tgaaataatg
     1201 gcgggagtaa cgacattctt tgccatgagt tatatcttat tcgtaaatcc gacgattttg
     1261 tcagcatcag gtatgccctt ccaagcagta tttctagcga caatcattgc atcgattatt
     1321 ggtacgctgg taatgggatt gttcgcaaat gtaccatatg ctcaggcacc tggtatggga
     1381 ttgaacgcat ttttcacttt tacggtcgtt tttgggcttg gttattcttg gcaacaagcc
     1441 ttggcaatgg tgtttatttg cggattaatc aatattttta ttactgtcac aaatattcga
     1501 aaaatgatta ttcgggcgat tcccgaaagt cttcaacatg cgattggtgg cgggatcggt
     1561 attttcgttg cgtatgtcgg aatcaaaaat gcaggattct tatctttttc agcagaccag
     1621 tcagctattt cgagctctgt cgttgaaggc ggaaaagcga caaatgttac gataaatggt
     1681 ggaatcgtcc ctgcgttagc caactttgac aacgctccta tcttattggc tgtgattggt
     1741 ttggtactga cagccatttt agttgtaaaa aatgtccgtg gggctattct tatcggtatc
     1801 gtagcgacca cagtccttgg tatttttatg ggtgttgttg atttaagttc cattgattgg
     1861 caaacgaatt cgttaggtaa ttcatttaaa gaattaggaa caactttcgg tgcagcattt
     1921 ggttctgaag gcatgcaatc tttattcagt gattcttcca agattcctca agtattgatg
     1981 acgatcatcg cattcagttt atctgatact ttcgatacga tcggaacatt tatcggtaca
     2041 ggacgccgca caggtatttt ctcaaaagaa gacgagatcg cgttggaaga tggtcgtggg
     2101 ttcaaaacaa aaatggataa agcactattt gccgatgcga tcgctacttc tgtgggggct
     2161 atctttggta catcgaatac aacaacttat gtcgaatctg cagctgggat cggggccggt
     2221 ggacgtactg gtttgacttc agtagtagtg gcagtgctat tcgcattaag tagtttattc
     2281 tctccactga tcgccattgt accaaatcaa gcaactgcgc cagcattgat tttagttgga
     2341 gtaatgatga tggcttcttt tgcagacatc aaatggctag atatggaaga agctttaccg
     2401 gccttctttg catcgatctt tatgggattg tgctatagca tttcctatgg gattgcagca
     2461 ggatttattt tctatacaat tgtgaaagta atcaaaggaa aatacaatca agtttctgtt
     2521 gctttgtgga tcgttgatat tttattcatt atcaacttca tcattctagc aacaatttaa
     2581 ctaaagagaa gggattggaa cagtatttgt tctgatctct ttttgtttta cataaaaaga
     2641 acgttacata taaaatgacc tttgcgggat ttttctcttt ttactggcga gatcgttgct
     2701 tgtttattcg aaaataggta tgataaaaga gacgaaagag ggatgataga tggagattaa
     2761 ttggagaaaa aatttagtga ttgcgtggat tggctgtttt ttcactggtg caagtattag
     2821 tttagttatg ccattcatac cagtttatgt tgagcaacta ggaacaccaa aagatcaaat
     2881 cgaattgttt tcgggactag caatctctgt gactgctttt gcatctgccg tggttgcacc
     2941 aatctgggga aatctagctg atcgaaaagg ccgaaaactc atgatgatcc gtgcagcagc
     3001 agggatgaca ttaacaatgg gatctttggc ttttgtacca aacgcgtatt ggcttttgat
     3061 catgcggttt tggaatggga ttttgtctgg atatattcca aatgccacag cgatgattgc
     3121 ttcacaggca cctagagaaa agagcggatg ggcgttagga acattgtcta ccggagcgat
     3181 tgctggaaat ctgatcggac cttcaatggg cggtgcactg gctcagtggt ttggtatgga
     3241 aaatgtattc ttgatcacag gggctttgtt gatgatcaca acggtattga ccattttctt
     3301 agtcaaagaa gatttccatc caatcgagaa aaaagatctg ataagcacca aagaaatttt
     3361 ttcaaaaatg gatcatctct ctattttgat cggtctcttc attacgacct tgattttaca
     3421 gataggaatc actacgatca gccctatttt gaccttatat attcgtgaat tgagcggaag
     3481 tacagaaaat atcctttttg tcagcggctt gattgtttcg atagctggtg tttccgctgt
     3541 cttttcttca ccgaaactag gaaaactagg ggataagatt gggaatcaaa aagttctaat
     3601 tggaggactc attttatcat tttgctgtta tttacctatg gcattcgtca ctacaccgct
     3661 ccaattaggt atacttcgct ttattttagg cttttcaact ggcgctttga tgccttctgt
     3721 caatacactg atcagtaaga ttacgcctca agaaggagtc agccgaatct atagctacaa
     3781 tcagatgttt agcaactttg gacaagtttt aggtcccatg ctaggatcga cagtcgcgca
     3841 tgcttataat tacagtgctg tttttattgt gacaagtttg tttgttctgt caaatattct
     3901 tctttcttta ttcaactttc gtaaagttct tcgcagcaga ttataatggt ggtgaggagt
     3961 agaaaataaa aaagagcttg agaaatctca agctcttggc tgttttttta cgaatgggca
     4021 gaggtttctt ttcttggcgc aactgcacca atcaaaagga taatgacacc cgcaatgaat
     4081 gaaatgattg ttgtcaaagt aaaatcatat gttccgcttg ttaatgcagc accaatataa
     4141 ccgactactt gacctagaac gacagcccag aataatgtaa cgatatatcg cataaagaac
     4201 acctcttttc tatcttaatt ttaccagatt ttctttgaat gtaaagaaac gagaccaaat
     4261 ctcaataaaa tttgagttct tgcgaaagaa ctcattccta cagattacaa gcaagcaaat
     4321 gaagtggaat aatcaacttc agcgcctgct atcttaatga aagtaaaagg atcaaacctt
     4381 ttaacgctag tgaattttaa cgaaaaaaaa ggcggaatgc aagatgtttt tcccacaact
     4441 ttatacaatt acttcttatt ctcttttaca aagtacgata cgtattcgag aatatgtaca
     4501 agaagcaaaa aaacaaggct acacttcatt agccataacg gataaagatg tcttatacgg
     4561 tgcacctgaa ttctatcgta tttgtgtaga agaaggagta cagccaatca ttggattaca
     4621 tcttagttat acttatgaag aaaaaaatta tggcttgctt gcgtacgcaa aagatgaaat
     4681 aggttatcag cagctgatga aactttccag ccgaaaaatg atccaagaaa aattggaact
     4741 tgcagaaatg acagaaaccg accatctagc gtttgttgtt ccggcaaatc attctgtttc
     4801 tgaggctttc aataaagagg ataacttttt cggtcattgg cagtttttac ttgaaaatgt
     4861 ttttactaga aatttttata tcggcttgac agaaaacacg cctgatcaat tgcctgaatg
     4921 gtatcagtat gtgataaaag aaaattattc gctttgtgca ttacatccca tcgctagttt
     4981 acaacaagaa gaactttttg cacttgaagt gatgaaacat atcaaagagg gaagccaaat
     5041 acctttagaa aatttatctg catctttacc actaacagca aatgtctatc ttctttcaga
     5101 acaagaaatg atcaaacgat tcgaaaaagc gggtctttcc caagctgtaa taggcgccca
     5161 gcgtttagct gaatcgattt catttgaatt ccagttccat cagaaattac ttccgcatta
     5221 tccagttcct aatggaaaac aagctggaga atatttaaga gagttatgct attcgcaagt
     5281 ggaacgccga atcactgact atacaaagga ataccaagaa cgtttggact acgagttatc
     5341 tgtcatccat caaatgggat tcgatgatta tttcttgatc gtatgggatg taatggcttt
     5401 tgctcataga aacaaaatcg ttaccggtgc aggtcgtggt tctgctgcgg gttcattagt
     5461 agcctatgtg ttagaaatca cagatgtgga tccattagaa tatgatttgc tgttcgaacg
     5521 ctttttaaac cccgaacgct ttacgatgcc agatatcgat ttggatattc ctgacaatcg
     5581 acgtgaagaa gtattgaatt atgttcgaga aaagtatgga caatatcata tggcacaaat
     5641 cgcaacattt ggcacaatgg cagcaaaaat ggttcttaga gatgcagcta gagtgtttgg
     5701 tttatcgcaa agtgaagcaa accgctggtc aaaagcaata cccaatcaat tgaaaatcac
     5761 attgacccaa gcttataaaa cttcgcatca attagtagaa ttagttcagg caagcgaaaa
     5821 aaaccaactt ttattcaaaa ctgcagtgat tttagaagga ttgccaagac atgtttcgac
     5881 tcacgcagca ggtgtagtta tcagcgataa gaatctactt gaactagttc cgctccaacg
     5941 cggttctgat gaagcttttc tgacccagta tacgatgaat gaggtagaag caatcggtct
     6001 tttgaaaatg gactttttag gactacgcaa cttatcgatt attgatttta ctttgaaagc
     6061 tgttaagcga gtagaagggt atgagatccg attaaaagag atcccgctaa atgatgcaaa
     6121 aacgctgctc ttgtttcaac gaggcgaaac ctcaggagta tttcaatttg aatctgctgg
     6181 tatccggaac gttttacgaa gattagatcc agaaaacatc gaagatattg ccgcagtcaa
     6241 tgcattgtat cgaccaggcc ctatgcaaaa tatagatacc ttcattgcca ggaagaaagg
     6301 aaaagaagcc attcgctacc cagatgattc actgatcccg attttgaaaa acacatatgg
     6361 agtgatcgtc tatcaggaac aaatcatgca gatcgcctcg actatggctg gatttacatt
     6421 agggcagtca gatattctgc gacgggcagt gagtaaaaag aaaaaagacg tattagatga
     6481 agaaaagtcg cattttgtat caggagcatt acaacaggga tattcggaaa aaacagcagc
     6541 gaccgtatat gaatatatcg aaaaatttgc aaactatgga ttcaatcggt cacatgcatt
     6601 tgcttattca ttcgtgggat tccaaatggc gtatctaaaa gcccatcatc caggtgcttt
     6661 ctttaccagc ctgatgaatt ctgttcggca taacacatca aaattgaaag aatatattgc
     6721 agaagcacgt aaaaataaac tcaaactttc ctcgccgtcc attaatcaaa gtaattccag
     6781 ttttgagttg gtcaataagg aagaaatcag attcggactg acagcgataa aaggtattcg
     6841 gcgtgatttt gtagaagata tattaaacga aagaaaacaa aatggcccgt tccagtcagt
     6901 ggatcaattc ctcatacgga tcgataagcg ttggctgaaa ttagagttac tgcaatcact
     6961 gacagcagta ggagtttttg atgaattatc tcctaacagg aaacaattga tgcttgatct
     7021 cgaaggaaaa atccaaaata tcgtttacag tggtggaagt cttgacttgc tgggaatcat
     7081 ggcattaaaa gaagaagaag tcgctgacta tacactagaa gaacgcttga agctggaaga
     7141 ggagtactta ggtatttatt tgtcaggtca tcctgcagaa gggtttgatc gtcttcgttt
     7201 agctaaacaa gttcagctga ttacagatat cgtccctaat caaccagtca atttattagt
     7261 gatgatcaag gaagttagag aaattcggac aaaaaaagga gaactgatgg cctttgttga
     7321 aggaaccgac agtagtggag aaatttctgt cacagttttt ccaactcttt atcgtaaata
     7381 tcgtaatttg tttgccgttg atcgagtgat ctttgttcaa gggcggagcg aaatcagcaa
     7441 atataatcag gaactgcaac taattggaga aagctttgct gatcctaacc agttagaagc
     7501 ccagtatcct tcacaaactt gctatttgcg tattacagaa gaacgggaag atcccgagat
     7561 aatgaaacaa ttacaagtga tttttcagaa acacccagga tatataccag tagttatgta
     7621 tcacgaaaaa acgcaacgaa aagtagttct gtcagatgct tattgggtgg atgacagcaa
     7681 gagtataaag cggcaactta tttatctgct tggcgaagat aatgtggttt tcaaataact
     7741 tacggtaaaa aatactactt gctttcattt tttttcattt ttttatccgt aaatcaagac
     7801 aagtgagaaa aataatgtta gaatgttagt cgtggttaac gcaaaaatgg ttgtaaacct
     7861 aagtcatact taggataaag tattttaatg aggtgaatgt ttattatgaa acgcatcgga
     7921 attttgacca gtggcggaga cgcacctgga atgaatgcag ctgttcgtgc cgttgttcgt
     7981 aaaggtattt acgaaggact ggaagtatac gggatcaatt atggttttgc cggtttagtt
     8041 gctggagata ttcgtcgtct tgatgtggca gatgtaggtg acaagatcca acgtggtggt
     8101 acattcttgt attctgcacg ttatccagaa tttgcaactg aagaaggtca attaaaagga
     8161 atcgaacaat tgaaaaaatt cggaatcgaa ggtctagtgg ttatcggagg agacggctct
     8221 tatcatggcg caatggcttt gacaaaacgc ggtttcccag cagtaggtat tcctggaaca
     8281 atcgataatg atattcctgg gactgatttc acaatcggtt ttgatacagc aatcaataca
     8341 gtactagaat caattgaccg tattcgtgac acagcgactt ctcatgttcg tacattcgtt
     8401 atcgaagtaa tgggacgcaa tgcaggagac atcgctttat ggtcaggtgt ggctggcgga
     8461 gcggatgaaa tcatcatccc agaacatgat tttgatatgg cttcagttgc taaaaaaatc
     8521 caagaaggcc gcgatcgcgg gaagaaacat tgcttgatca tcttggctga aggtgtaatg
     8581 ggcggaaatg aattcgctga gaaactttca gaatttggtg actatcatac acgtgtatct
     8641 atcttgggac acgttgtccg tggtggagca ccaagcgcac gcgaccgcgt gttggcaagt
     8701 aaattcggtg cttacgctgt cgaattgctt caagaaggaa aaggtggatt atgtgtcggt
     8761 atccatgaca acgaaatcgt tgcgtctgac atcattgata cacttgaaaa caacaaacat
     8821 aaaccagact tatcactata tgatctaaat aattcacttt cattttaaga gtgaaagaaa
     8881 ccaagctatt taagctgtgt acagctttaa ataaacaaaa ttgaatggga gagtttttta
     8941 aatgaaaaaa accaaaatcg ttagtacatt aggaccagca agtaactcag tagaaattat
     9001 ttctcaattg attgaatctg gggcaaatgt cttccgcttt aatttttctc atggtgacca
     9061 tgaagaacaa ttatcacgta tgactatggt ccgtgaagca gttaaaaaga caggaaaaga
     9121 tgtcggtatt cttttagata caaaaggagc tgaaatccgt acaactgttc aaggcacaac
     9181 agaagctgat tttggtcgtg caggatacat caaatttgaa gtaggagatc aaacacgcat
     9241 ctctatggat cctgaacatg taggttcaaa agaaaaaatc gcggttactt acccaggatt
     9301 atttgacgat gttcacgttg gcggacacat tttatttgat gatggtttga tcgatatgca
     9361 aatcattgaa aaagacgaag caaaccgtga attagtcgta gaagttaaaa atgcaggtat
     9421 gctaggatca cgtaaagggg taaatgcacc aggcgtttct attagtttgc caggtattac
     9481 tccaaaagat gctgacgata ttcgttttgg tttagacaac gatatcgact ttatcgctgc
     9541 aagttttgta cgtaaagcac aagacgttct agatatccgc gaaatcttag aagaaaaaga
     9601 catgactcat gttcaaatct tccctaaaat cgaatctcaa gaaggtatcg acaacattga
     9661 cgaaatcatc aaagtttctg acggtgttat gattgcccgc ggagatatgg gtgttgaaat
     9721 cccagctgaa ctagtaccaa tggttcaaaa acgcattatc aaaaaatgta atgctgctgg
     9781 tatcccagtt atcactgcta cacaaatgtt agaatcaatg caagaaaacc cacgtccaac
     9841 acgtgcggaa gcttctgacg ttgctaacgc tgtatttgat ggcacagatg caacaatgct
     9901 atctggtgaa tctgcaaacg gggactaccc agttgaagct gtttcaacaa tggcacgtat
     9961 cgaccaagaa gctgaaaatg cattatcaga attaggtaca ttccaattga acgaattcga
    10021 taaaacagat gtaactgaaa caatcggttt atctgtagct cgtgctgcaa aaaatctagg
    10081 cgtgaaaaca atcgttgctg caactgaatc aggatacact gcaaaaatga tttcaaaata
    10141 tcgtccagat gcagatatct tggctgttac ttttgacgaa cgcacaaaac gtggtttgat
    10201 gttaaactgg ggcgtttacc caacagttgc tgaaaaacca tcaacaactg atgaaatgtt
    10261 tgaactagca gctaaaaaag ctgttgaatt aggtttcgca tcagaaggcg atttaatctt
    10321 gatcactgct ggtgtaccag ttggtgaacg cggaacaact aacgtgatga aaattcaaat
    10381 gattggttct aaattattag aagctcaagg cgttggacaa aaatctgtcg ttgcaaatgc
    10441 agttattgct tcatctgctg aagaagctgt aaaaaaagca aaagacggaa tggttctagt
    10501 tgtaccatca actgacaaag aatatatgcc tgcaatcgaa aaagcagctg ctgttatcgt
    10561 tgaagaaggc ggattgactt ctcacgctgc agttgtagga attgcacaag atattcctgt
    10621 aatcgttggt gctaaaggcg caacaacaac aattacagaa ggtgaattga ttaccgttga
    10681 ttcacgtcgc ggcatcgttt accgtggcga aacaacagct atctaattta gcttaataaa
    10741 aaataaaaac agctcttctt ttacgaagag ctgttttttt gtgctgtaac gaattcatgg
    10801 ataacttgga ctacttgttc ttgaagaggc gtgacgatct gctgtgttcg ttttgccaat
    10861 gaaatcaaga agcgaggctg aacttcatct gaaagaggga ggcaaactaa atgatcttca
    10921 ggatggacag caatctctgc caaaaaaccg atacccacat tttctcggac catactcttt
    10981 aaaatcgtca agtcattgct ttgataaaca acttttggat gagtatgtgt ttgtttagaa
    11041 agcttagtga atgctgcggg gtggacataa tgttcgttca atagtacaaa ctgttcatct
    11101 gctatatctt tgaaagagac agtatcctgc ttggaaagag gatgtgtagg tggcacgacg
    11161 atcatgaaac gtttgtccaa aagtaactct gtttctaaat attgatccac gattggctgt
    11221 gttgagccta atacagctaa atcgatcctc ccttgtcgga tcatcccgta taagtcccga
    11281 gagcctccat cggtaatctc aatttgattc atcaattcat gcttgataaa gtaacttgac
    11341 agtttaggaa agtattcatt gccgataata ggaggcatgc caaaacgaag ctttttcttt
    11401 tgcaactgag tgatttcagc tcttgcagta gaaatctctt ggagaatggt ttgtgcatgg
    11461 agaaacagct gctttccaga aggcgtgacg attaattcgt gatgcgatcg atctcttgta
    11521 ataagtacgg tgtcaaactc tttttcaaga cgttgtaatg catatgtaat agtaggttgg
    11581 ctcacacgga aataattagc cactttcgta aaattttttt gtttgacgat ttggacatag
    11641 tattcgatat ctttcgtgtt catgaagatc atccgctcct ttaatggaat aatgattatt
    11701 gtaaatgatt ctgaggatga tagcaaacag aggctttcta ataaagattt ttctgttttt
    11761 ttatgaactg caaggtgtca agaaaatttc attgacaaca tgctttttgc cctgtataat
    11821 tgcttttgtt gcttaggagt gatgaaaaat gaaatggtct ttattggaat tgagaaaata
    11881 ccaggagaca ccgttaactt ttcatgagac gctcgacttg aaagccgctc tcatgaagcg
    11941 agacaattta atacttgatg ttgcgccagt ggaagtcgaa ggtttggtct cagttgataa
    12001 gaaaggctat atcgttcatt acactgtgca gacgactttg acagttcctt caacacgttc
    12061 actagaacct gttgaactgc ccatggattt ttctgtagac gaagtattca tgacagaaga
    12121 acaattccaa agtagagatg aacaaatgtc tgcggatgag attttgctaa ttgaaggtcc
    12181 attattgaat ttagcagagt cgattgaaga caacatctta ttggcgattc caatgcgggt
    12241 attgacaaaa gaagaggaag cagcaacaga acttccaaaa ggcaatgatt gggaagttgt
    12301 ttccgaagaa gaataccagc gcagaaaaat ggaagaagcc gagaataaaa ttgatcctcg
    12361 tcttgcaaaa ctatctgaac tttttgattc taaatcaaaa gacgacgata acaagtaaga
    12421 ttggaatata ttgtgtctaa tttagataca agactttaca aggaggtgta gcaaaatggc
    12481 agtaccagct agaagaacat caaaagctaa aaaagcaaaa cgtcgtacac actacaaatt
    12541 gacaatcaaa gggttaaacg aatgtccaaa ctgtggtgaa atgaaaaaaa gccatcacgt
    12601 atgtgcaaat tgtggttact atgatggtaa ggacgtaatg tcaaaagaag cttaatacat
    12661 tttaattaga aaatgtaaaa cctcaaggct aaccatggag ccttgaggtt tatttttttg
    12721 tagtcggtaa ataaaaaata tgttgttctt tagtttgcaa tgtagccgtg ttaagctata
    12781 atgtaagaga ttagggagaa atcccgtatg taggaggagt tcatatgtca aaacaacaaa
    12841 tcggcgttgt cggtatggcc gttatgggta aaaatctagc cttgaacata gaaagccgcg
    12901 gctattcagt ggctttattc aatcgtacag gggctaaaac aaccgctgta gtagaagaac
    12961 acccagataa aaatttcaaa gcaacatata caatcgaaga atttgtagaa tctatcgaga
    13021 aaccacgtcg gatcttgcta atggtcaaag caggaccggc aacagatgca acgatccaag
    13081 agttgcttcc tcaccttgat aaaggcgata ttttgattga cggaggaaat acattcttta
    13141 aagatacgat gcgtcgtaat gaagagttag ccaactctgg catcaacttt atcggtacag
    13201 gcgtttccgg tggtgaagaa ggagctttaa aaggaccttc aatcatgcct ggtggacaaa
    13261 aagaagccta tgcgctagtt gcaccattct tagagcaaat ttctgcaaaa gcagaagacg
    13321 aagcaccatg tgtcacatat attggcccaa atggagccgg acattatgtg aaaatggtac
    13381 acaacggtat tgagtatgga gatatgcaac tgattgctga atcttatgac ttaatgaaga
    13441 atattttaaa cctttcagta gaagaaatgg ctgatatctt taaagaatgg aatcaaggcg
    13501 aattagacag ctatttgata gaaatcactg ctgacattct gacacgtaaa gacgatgaag
    13561 gaacaggtaa accagtagta gatgtgatcc ttgatgcagc tgggaataaa ggaacaggta
    13621 aatggacaag ccaaagcgcg cttgacttag gtgtgccact tccattgatc actgaatctg
    13681 tatttgcccg ctatatttct gcttataaag aagaacgcgt acaagcaagc aagattttat
    13741 ctcgtacgaa cgattttgag ttcacgggag acaaaaaaga attggtcgaa aaaatccgag
    13801 aagcgttgta tttcagtaaa atcatgagtt atgcccaagg atttgctcaa ttacgtgtcg
    13861 cttcaaaaga atttgattgg gacttgccat ttggtgaaat cgcaaaaatc tggcgcgctg
    13921 gatgtatcat ccgagctcga ttcttgcaaa aaattacgga tgcctatgac aaaaatcctg
    13981 agatcgaaaa tttattgcta gatgattact tcgttgaaat cacgaaaaaa tatcagcaat
    14041 cagtcagaga cgtcgttgcc ttggctgtcc aagctggcgt acctgtaccg actttctcat
    14101 cagccatcgc ttacttcgat tcatacagag cagaacgtct gcctgcaaat ataatccaag
    14161 cccaacgcga ttactttggc gcacatacct atgaacgtgt cgacaaagaa ggaatcttcc
    14221 attactcatg gtaccatgaa gaataatagt ctttcggctg ttaggaaatg agaaaataaa
    14281 aagaggacga aagagctgaa gtcgattgtt atgagtagac ttcagctctt ttttaaaatt
    14341 gctatccatg ataaaatgac tatagatttt taagcatatt atcggtataa tgatagagtt
    14401 tttaaaaagc cagtagaata gaaaggataa aataataaat gagcaatatt ctaatcattg
    14461 aagatgaaaa gaacttggca cgatttgtcg agctagagtt gaagcatgaa gggtataacg
    14521 cagaagtcca ctacaacggc cgaactggtt tagatgcggc attaaataat gagtgggatg
    14581 ccatattgtt ggatctgatg ctcccagaat tgaacggttt agaagtctgc agacgtgtac
    14641 gccaagtcaa aaatacacca atcattatga tgactgcaag agattctgtg atcgatcgtg
    14701 tatctggact tgaccacgga gcagatgact acatcgtcaa accatttgct atcgaagaat
    14761 tattagcacg tcttcgtgca ttgttgcgtc gaatcgatat tgaaggcgat aaaaatgtgg
    14821 ctaaacaaac tactattact tatcgcgatt tgactatcga aaaagaaaac cgtgtcgtac
    14881 gtcgcggaaa tgaagtaatt gaactaacaa aaagagaata cgagttgctg cttactttaa
    14941 tggaaaacgt gaacgtggta ttagcacgtg acgttttact aaataaagtg tggggatacg
    15001 aaacagaagt tgaaacaaac gtagtggacg tatatattcg ttatcttcgc aacaaaattg
    15061 acgttcccgg ggaggaaagc tatatccaaa ctgtacgcgg aacaggttat gtgatgcgct
    15121 cgtgataaag ccgaaaaaat cggaaaaaag agaactgaaa gggccctcct tgacaatcaa
    15181 gtgggccttt gcgagttctt tcttcatatt cgttgtgttt acaattttcg ctgtcattac
    15241 ctataaatca tctatcaatc tgattgtggc aaaagaaaga aacaatgtag agcgtacgat
    15301 ttcagaagta gcttctcgtt tggctaactc ggatgaagaa ctgacattag taaatacgta
    15361 tcgtaatctg acgaaagcga caaatgacgg agatgaggtc gtagatcata cttcactggt
    15421 cgaaggaaac ttaatgaaga tcgattcctt tatagctgag ctagggcagc catcaatgga
    15481 tctttatgtt tatgatttgg acgagaactt gatttttaaa acccatgaaa acagtcgaaa
    15541 cctgattcag actacacgta aagttccaac gatcgttaca ctagaaggaa aaactggctt
    15601 tttatctatc cagcctatat attctaaagg tacaagagaa aagatcggct atgcgcaaag
    15661 cttctatgaa ttatcttctt tctatgatat tcgaaataag ctattattga ctcttattgt
    15721 tttagaagtt gtttctttga tcttaagtag tattttaggt ttctttttat cttcttattt
    15781 cttaaaacca ctcaaggtac tcagagatac aatggatact atacgtaaag atccgcaatc
    15841 agatatccac atgcctgaaa tcgacacaaa tgatgaattg gcagatttag ctgaaatatt
    15901 caatgagatg cttgaccgta tgcgtttgta tattgaacaa caagagcaat tcgtggaaga
    15961 cgtatctcat gagttaagga cacctgttgc aattattgaa gggcatctta gtctgctaaa
    16021 tcgttggggg aaagatgatc ctgagatatt agaagaatca ttaagcgcca gcatgcaaga
    16081 aattagccgt atgaaaagct tagttcaaga gatgctagac ttatcaagag cagaacaagt
    16141 agatgttcat tatgcgaatg aaacaactaa aggaaaagaa gtcacctatc aagtttataa
    16201 taatttcaag atattatatc cagactatgt gatcacttta gatgatgatt tgacaaaaga
    16261 agtgaccctg caaatttatc gtaatcactt tgaacaatta atcattatca tattggataa
    16321 cgcagtaaag tattcaacta cacgaaaaga agtccatatc tctatttctt ccactctgaa
    16381 tgaatttgag atcgcgattc aggactttgg cgaaggaata cccaaagaag accttaataa
    16441 gatcttcaat cgtttttatc gagtggataa agcaagagct agaacgaagg gtggaaatgg
    16501 tctggggttg tctatcgcta aacaactggt tgaaaactat aaaggacgta tcttagcaga
    16561 aagtgtagta gggcaaggga caatttttag aatctttatt cctatcgcaa aggcagaaga
    16621 caagtaaagc atgtgcttta cttgtttttt tatatatcca acaaagaata aggtacaaaa
    16681 tacaagcaag ttagaaattc agggatgtca ttataaaaaa aactagcgaa caattaaata
    16741 gaataacatc cgttaattaa acgtaagtag cttttagatg aacgaaaaaa caatgaaatg
    16801 ctgtaatatt cgtgtttaaa aataataaat aaaaataggg aattttctat tgcaatttta
    16861 taaagagatt gctatattat tatttgttct aaatgattcc tttaaggtgt cactaaaaat
    16921 tataaaaaat agggttgacg cacttttgat gtcatgttat aataacgaag tcgtttggat
    16981 gaggtagcta ataaagcttg attttatcga aaaaaacttc gaaaaagttg ttgacaaata
    17041 acaataaaga tgatatgata atcaagtcgc tgctaatgag tgacaaagac gtttagaaaa
    17101 aataaacaaa gaagttgttg acattctctt ctgaatctga taagattaaa gagttgttga
    17161 aacaaaaaga
//
LOCUS       DAZULR010000052        16581 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.053, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000052 DAZULR010000000
VERSION     DAZULR010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16581
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.053"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            72..506
                     /locus_tag="ACG8ZV_002169"
     CDS             72..506
                     /locus_tag="ACG8ZV_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4997454.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(584..1117)
                     /locus_tag="ACG8ZV_002170"
     CDS             complement(584..1117)
                     /locus_tag="ACG8ZV_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HFS4997455.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(1211..2389)
                     /gene="mutY"
                     /locus_tag="ACG8ZV_002171"
     CDS             complement(1211..2389)
                     /gene="mutY"
                     /locus_tag="ACG8ZV_002171"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HFS4997456.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(2382..3179)
                     /gene="recX"
                     /locus_tag="ACG8ZV_002172"
     CDS             complement(2382..3179)
                     /gene="recX"
                     /locus_tag="ACG8ZV_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HFS4997457.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            3286..4668
                     /gene="rlmD"
                     /locus_tag="ACG8ZV_002173"
     CDS             3286..4668
                     /gene="rlmD"
                     /locus_tag="ACG8ZV_002173"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFS4997458.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(4842..5420)
                     /locus_tag="ACG8ZV_002174"
     CDS             complement(4842..5420)
                     /locus_tag="ACG8ZV_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HFS4997459.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            5742..6212
                     /locus_tag="ACG8ZV_002175"
     CDS             5742..6212
                     /locus_tag="ACG8ZV_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TspO/MBR family protein"
                     /protein_id="HFS4997460.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(6320..7546)
                     /locus_tag="ACG8ZV_002176"
     CDS             complement(6320..7546)
                     /locus_tag="ACG8ZV_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFS4997461.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(8300..8500)
                     /locus_tag="ACG8ZV_002177"
     CDS             complement(8300..8500)
                     /locus_tag="ACG8ZV_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFS4997462.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(8634..9242)
                     /locus_tag="ACG8ZV_002178"
     CDS             complement(8634..9242)
                     /locus_tag="ACG8ZV_002178"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HFS4997463.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(9327..9797)
                     /locus_tag="ACG8ZV_002179"
     CDS             complement(9327..9797)
                     /locus_tag="ACG8ZV_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HFS4997464.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(9845..10759)
                     /locus_tag="ACG8ZV_002180"
     CDS             complement(9845..10759)
                     /locus_tag="ACG8ZV_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFS4997465.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            10905..11708
                     /locus_tag="ACG8ZV_002181"
     CDS             10905..11708
                     /locus_tag="ACG8ZV_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HFS4997466.1"
                     /translation="MTTKQLIISSFIRFKDLKESRNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            11886..12833
                     /locus_tag="ACG8ZV_002182"
     CDS             11886..12833
                     /locus_tag="ACG8ZV_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HFS4997467.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(12901..13194)
                     /locus_tag="ACG8ZV_002183"
     CDS             complement(12901..13194)
                     /locus_tag="ACG8ZV_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HesB/YadR/YfhF family protein"
                     /protein_id="HFS4997468.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(13222..13887)
                     /locus_tag="ACG8ZV_002184"
     CDS             complement(13222..13887)
                     /locus_tag="ACG8ZV_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HFS4997469.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(14027..14659)
                     /locus_tag="ACG8ZV_002185"
     CDS             complement(14027..14659)
                     /locus_tag="ACG8ZV_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFS4997470.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(14666..15733)
                     /gene="liaS"
                     /locus_tag="ACG8ZV_002186"
     CDS             complement(14666..15733)
                     /gene="liaS"
                     /locus_tag="ACG8ZV_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     LiaS"
                     /protein_id="HFS4997471.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(15730..16461)
                     /gene="liaF"
                     /locus_tag="ACG8ZV_002187"
     CDS             complement(15730..16461)
                     /gene="liaF"
                     /locus_tag="ACG8ZV_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein
                     LiaF"
                     /protein_id="HFS4997472.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
BASE COUNT         4982 a         3346 c         2678 g         5575 t
ORIGIN      
        1 tttgaaaact tgccatactt tttatttgtt ttattttcca gtatactata cgaaaggaag
       61 gtggctagac catgaaagtt gtacaaacaa aagatacaat gagcaatatt tacttagatg
      121 ctgtacggat caggcatcaa gtttttgtag tcgaacaggg tgtgcctttg tctcgagaaa
      181 tagacaaaga tgaagcccat tgtatccact tcgtcctgta ctcagataaa aaagaaccgc
      241 aaggaactgt acgtcttttg cctttagaaa acggaaaaat gaaattacag cggatggcga
      301 ttctttctga atacagacac caagggttag gaaaaatatt gattgaagaa gcagaaaact
      361 ttgctaagaa tcaaggctat aatacgattt tattaggggc acagtccaca gctgaaactt
      421 tttacgaaaa actaggatat acagcttacg gcgatccttt tgaagatgct ggcatgcctc
      481 atatttatat gaaaaagact ttataaaaat ttatttcgaa aaaagcaaaa aacagcaagc
      541 ttttgagaaa aatctctcac tggcttactg ttcttttttg tgtttactta cgcgacaatt
      601 gcttgtaacg gttataccaa atatcaatat agccttccga gaacgggcca tctccattat
      661 tgatccagtc aaccagaatc ttcacatttt cttttaggat gaagtcaata tcgttcgggt
      721 aattcatcat tttgctgtgc atctcatatt catcgacatc caatagtcgt ttctcgccgt
      781 caggaaatac cttgatatcc aagtcatagt cgatatattt caaggcctca tcgtccagca
      841 aaaaaggtga agctagatta caataatagg aaaccccctt ttctctgatc attgctatta
      901 cattgaacca gtatttttta tgaaaataaa caatcgctgg ttcgcgcgtt acccatcggc
      961 gtccatcaga ttcagtgact aatgtgtgat cattcacgcc gatcatagag tgttcgcttg
     1021 tttttaatac catggtatct cgccacgttc gatgcaattt gccgtcgtgc ttgtaacttt
     1081 ggatcgtcac aaactctcct tcttttggaa ctcccatagc aacccttcct taagcagcat
     1141 tttgtgcttt gtgtttgggt gttcattaca ccgacatcat aattattata tcaataaaaa
     1201 tgagctttgc ctagaaagga ttcctattgt ttcgattttt ctctaactga tctaccagtt
     1261 tcatttggac cttaggaaaa acgaccgaat caaatgcatc aggcttcaac cacttcgaag
     1321 ttttgttctc ggtaaattct tgttctgctc cctcggttgc ccgtccgtaa aaaaggagaa
     1381 catgccattt cagatgacta aaaatatgag taacttctcc taaatgtcgt gtctgccaaa
     1441 caaagagttc ctgcttttca aatgggagat tttgctcttc ttctgctact aggtcatcaa
     1501 acagatcgat ttctggcttt gtttcccatt cttttttcaa tcgctcatac tcctcttgtg
     1561 tcacttccat cattggaaat gtccacatat tcgccagcaa tttttggcta tctctttctt
     1621 caaaataata cgctccagaa tgattttgaa gagctgcact gatataataa acgtcttttg
     1681 gctttgcttt ttttgttttt acaggaaaac tcgtttggat tcctcgtttg ttagctaaac
     1741 aaaaggcttg gatcggacaa gtctcacact ttggagaagt tggtgtacag atagctgaac
     1801 ctagatccat cattgcttgg ttgaattcac ctggatgctt ttcatcaatg attttccgca
     1861 tcgcttcatc aaagattttc ctgctagaag cttttgcgat gtctgcttca atgcaaaaca
     1921 atctgctgac tactcgcatc acgttgccgt caactgcagg ttctggaagt ccaaatgcga
     1981 tacttgcaat cgcgcctgtc gtatatggtc ctattccctt caatgagcta atttcttcag
     2041 gcgtttgcgg catttcccca tcaaattctg acatgatctg tttagcagca gcttggatgt
     2101 tccgggctct tgagtaataa ccaaggccct cccatgcttt taaaagcttt tcttctggag
     2161 catttgctag ctcttcaatt gtaggaaacc attccatgaa acgataaaaa taatcgatca
     2221 ctgtgtctac tctggtttgc tgaagcatga tctcagagat ccagatacga taaggatcac
     2281 gattatagcg ccaaggcagg tttctttttt cttgttcata ccattgaatg aactgatctt
     2341 gaaattcttt tgtttcttta tctgtccatt tttcccattc tttattcact ttcctcttcc
     2401 ttttccgtaa tgaatcgctg gatcatatcc aaatcaaatc ctttttgata taagctttgc
     2461 tttactttta gatttctttt tttaggttca aaccttaaat ttcttcgcca tagtttatct
     2521 ccttgtttga ctaaataatc atattctatt tcttgatctg cttcttgcgg aagatcagct
     2581 atcgcttgtt ggatcacttc ttgagaaaag cctttcgtca tcaatgtttg ttggattttt
     2641 ctcaataatt ctttttggct ttttccgtga ttttttccaa acgctttttc ggctgtctga
     2701 tgtgcatttt gaacttggtc ttcaaatgta tattggctga gcgcttgttc aatgatttca
     2761 ggtttcaaac ctttttgctg catctgctgc gctaatttct ttggtccttt gtcacttaag
     2821 cgcatattcg tgcgcacata actttcccca tagaccaaat catcgacaag gtccaattct
     2881 tttaagcggg ctacgatttt atttcgatct tcttgaagga tttccttttc ttttaagtat
     2941 gttcggattt ctttttccga tcgcaactga taacttaagt aattcattgc taggtgaaaa
     3001 ccgaaatcag ctccgctact cttcttgatc tcttggatag tttcttcgtc taattcccgt
     3061 ccttttaata atcgatagcg tactaataca tcttcagata cttgtaaagc ttctccttca
     3121 gataaatcta cgcgatagaa agggcctttg cctttactga ttctcgtaac ggttaacata
     3181 aacatcctcc tcgaacatat attctctatc ataccacaga aaatccccgt aatcaggtat
     3241 tatatgttag aataaaccac agaaaaaaga aaaagggaga tacttatggc agaaacaatt
     3301 gtcaaaactg gacaaacggt tcctttgaaa atcaagcgtt taggcataaa tggtgaagga
     3361 atcggttatt tcaaacggtt gatcatattt gttccatatg cactaccaaa agaagaagta
     3421 ctagtgaaaa tcacgaaagc aactcctcgc tatgcagaag gagaattaat aaaagtcaaa
     3481 aaaacaagca aagatcgcgt agtggcacca tgtcctgttt actatgaatg cggtggctgt
     3541 caattacaac acttagctta tcaagctcaa ttggatttta aaaaggatct gcttttgcaa
     3601 gcattggaaa aattcaaacc agcaggcttt cgatcttatc aacttttgcc gacgatcggg
     3661 atggatgagc cttggcatta tagaaacaaa gcacaatttc agttacgaaa aaataagcag
     3721 actcaaaaaa ttgaagctgg tttatacgaa gcaaactctc atcagttagt ccctataaca
     3781 gactgcttgg ttcaagaacc tcgaacacaa aaagtaatga atactgttgt tcaactattg
     3841 aataaatttg atgcacccat ctatgatgaa cggacaaaca gtggaatctt ccgcacaatc
     3901 atggttagaa tcggtgttaa aactggggag ttacaagttg tttttattac tcgcagtaaa
     3961 aaattcccgc aaaaaaacgc aatgatccgt gagatcaatg aacgactgcc cgaagttgtt
     4021 tcaatcatgc aaaatgtcca ggcacaaaaa acgtctctcg tgatggggga tgaaacgatc
     4081 cacttatggg gaaaagaagc cattgaagaa caaatcaatg aagtgacttt cgatctttct
     4141 cctcgtgcct tctttcaact caatcctcag cagaccgaat tgctttatgg cgaaggaatc
     4201 aaagcattag atgtccagcc taatgaaacg atcgtggatg cttattgcgg agttgggacg
     4261 atcggcttaa gtgtagcaaa acaagccaaa gaagtacggg gaatggatac cgttcctcaa
     4321 gcaatcgctg atgcaaaaaa aaatgcggaa agattaggat atcacaacac tcgatatgaa
     4381 gtcgggacag cagagcaagt tctgcctaaa tggttgaatg aaggttttca gcctgatggt
     4441 atcatcgtag atccaccacg tacgggtttg gataacgcat tgatccaatc attattgaaa
     4501 taccctccaa aaaaacttgt ttatatctcc tgtaatgttt ctacacttgc cagagatctg
     4561 gttaatttaa gtaaaaagtt caagattgaa tatttacagt ccgtcgacat gtttcctcag
     4621 actgcacgtt gtgaagttgt cgtgaagatg acgagactcg ctgactaaat gaaagaggtt
     4681 gtgaaaaagt ctgccctgta tcaagtaata agaacagcca aacaaaaata gctcttcatg
     4741 ttttatgaat actgtacttg tgaccgaaga gttaacagga ggacactatt tatttaaaaa
     4801 aagggttgtg acatagtttt tgtcacagcc ctttttgatt attattggat attcacgtct
     4861 atcacttgat aaaatgcatt tgtcgtatcg ctgatattcc atactgctaa aatcacatta
     4921 tatccttttc gatcctgcgg aagtgtgatc gtttggttga ctgtttttgg tggaacagtt
     4981 gctttgtcgt ctatttttgt gatcaattca aaatcactaa atttcaaagg ttgattagga
     5041 ttccaagttg gtttggtaat gtagtaatcc caagtacttg tccgatgttg tgctgttaaa
     5101 ttccaagtaa tatttaatgt tcctggatta accatgtttt tatgccatct gttagatgtc
     5161 tgttcatcta aaggctcaaa gccgctgact cctgcactag caatttttcc atcaatgaat
     5221 gtatttttgg tagcttcgat actttgcggt tcccattgtg ctcttccgac attttgattt
     5281 aagtttcctg ctgctgatgt tcctaggtat gcacggcttc ctggagaagt aatataacca
     5341 tgcgcaaaac ctggaatgct aaaaccgaac aaccctaaac taactaaccc aataaacaat
     5401 aacgtactaa tctttttcat gtagaaacct ccttcatttg ataaccacat tgtaaacgct
     5461 ttattgtatt aacacaaaca ttatgctttt ataattttat gttgaagtaa aaaaggtgaa
     5521 aaaagtaaga tgcagattat aacagaagta gacgagaaaa gtacaaatag aaaacatgag
     5581 aatcaaatca tatgatcttt ttcaaaaaca tcattcatat aaacaaatgt tcaacttttt
     5641 aataacaaca attatcaatt tttttcttac ttcacaaact aaatacaggt cttgctgtga
     5701 gccttcatgg taaactaata ttatagaaag gagttagtaa aatgaagatg ataaaagata
     5761 ttcgtttttg ggtttgtgtt ataggaattg tcatattagg ctttttatca gggttgctta
     5821 gcggaaatcc cggaaaatat tactattctt tgcaacttcc accatttgca ccacctagct
     5881 ggatatttgg gccgatgtgg accttactgt atatattgat gggtatttct ctttatttgt
     5941 tacttaatca caacaacaaa aaacagcgaa acaatcttgt cggtcttttt gtgattcagt
     6001 tcatttttaa ttttatatgg tctgctctat tttttaattt aagaaatatt ttcattgcag
     6061 caatcgatat tacactttta gttattttct tgtcagtgct tatgtatcag ttgtggctgc
     6121 atcatcgcct ggcaatgtgg ctcatgattc cttattattt atgggtacta ttcgcaactc
     6181 tattgaatta ttcaatttat tttttaaact aagcgctaaa aagagacgtc ctgtaattta
     6241 acacatagaa aaagtgccac ctaagttaga ttttttgtct aatttaggtg gcactcttta
     6301 ttaaccaaac tatttttttc tagtacccac ttgttgttcc atactcatta ttctggtcat
     6361 aaccataacc attttgttcc tgtccagcgt aaggatcata actttgagta tcttgacttg
     6421 gtgtatagta ctgacttgta tcttctgttt gctgataata ggtattcgga tcttggtact
     6481 gatcatatgt gttttctgaa taggaagaat aatcggtgta cccttcacta ttcgatccat
     6541 caccgtttgt cgaatcgcca tcttccgaat catcaaagaa catcattgaa gcattctcat
     6601 ttttcaaatt aggtaatgta tcgcttgttt ttatatttaa ttgtttcttc agttcatttt
     6661 ggatcgaaag aagatcattt tttcctaaaa tttgatagta gatatcattg atcatttgtc
     6721 cttcgccttg caactggtct tgtttgattg tttcaaacgc cggggtgtag ttcgtcgcta
     6781 catcaagcat gtcatcccaa tctaagtccg tcgtcacatt gttctcaact gcttttaaaa
     6841 tttttctata attgcttacg ccatctaaac ttaaaacttt attgacgatt ttcgtcacta
     6901 cttcccgctg acgacgttgt cgaccgatat cgccttctgg atcttcgtgt cgcattcgag
     6961 aataggctaa acctttttct ccattcaatg tttgttcacc tactggtaca tggacaccat
     7021 ccaaagtaaa gtcaatttta ttattcactt tgatgccacc gaccgcattg atcaaatctt
     7081 ccatgccatc caaattgatc gttacataat gatcaatagg aatatcgagc agttgctcaa
     7141 ttgaatccat ggccatttcg acaccaccaa atgcgtaggc atgatttaat ttatctaccg
     7201 ttccataacc tacgatattc gtataaatat ctcggtccaa actgatgatc gttgattttt
     7261 tttgtttcgg attaactgtt actaccatca tcgtatcaga acgtccttgt tccgttcttc
     7321 ctaatccacc ggtatctaaa cctaatagca aaaccgaaaa aggttctttg tcatcaatgc
     7381 ttactctctc agaacgtttg gaggatattc gattagagtt tttagaaatt ttgtttactg
     7441 tttggctcgc ttctcccata aatctgattc cgtatgctga taatccggca atcagcaaaa
     7501 cgaatacccc taacaaggtt aatagaactt tttgccatcg cttcataata cacctctgtt
     7561 tcacattttc taaaatattg tctcatataa ctgttcaatc agcaaattca ctttttaatc
     7621 ataagaaaac tttaaaaaac atttttgtgt aacgattatt attttttaaa atttctcaaa
     7681 attcttaact atcataccat accgtgaaaa agatcgaaag accgaataca cgcagttcgc
     7741 aatcgtttta tcttttttta tgtatttttt ccagaaaaag cgaacaacaa ggtattttcc
     7801 aaataatcgt gcagtaaaat gatcgcacat acctttccca tctttttaac agtctttgcc
     7861 taccgttcag attatcattc gatttcacga caatttcttc ctatgactgg tccttttgtt
     7921 aaacccatct tctattcgtt ttatttccag ctcactgcat ggctcttaaa atgactcgaa
     7981 ctagtgattg cattaccatc atcttttaat ggatagatat gctcctcttc aaagtaaaac
     8041 gattttcttt taaagtaata gaattgacat ggtaatgagt atgtatacta gtggtttcac
     8101 aaatggtctt ttattcaaca tccaaaaact gaaatttctt taaaatccat tactaacgaa
     8161 gaaaatgttc cttgcttgat aattagttag gacatgtcaa gtgaacaaat gcatttactt
     8221 agccaaaaaa tctaaaaact tcataaatag acaaaaagac acgactctct aagaagtcgt
     8281 gtctttattc aacaaattat tataatttag tcacttcagc agcttgaggt ccgcgtgcac
     8341 cttcaacaat cgtgaattct acttcttgac cttcttctag gctcttgaag ccgtctcctt
     8401 gaattgctga gaaatgaaca aatacgtcat ctccgccgtc tactgtaata aacccaaatc
     8461 ctttttcatt gttgaaccat ttaaccgttc cgtgttccat aaatgtatat cctccaaaaa
     8521 agttcttgca agtaaccttg caagaacatt atacccaatt tagaaaacgc tagcaagctt
     8581 tcgctctttt attttccaaa ttatttttaa gactgatatg acggaggaaa tggttatttt
     8641 gctgcttcga aacgtttgtt tacttcatcc caattaataa cattccagaa tgctgcaata
     8701 taatctggtc ggacattttt atatttcaaa taataagcat gttcccaaac gtccaaacct
     8761 agaattggtg tctttccttc catcaatgga gaatcttgat ttgcagtaga ggtaatagct
     8821 aattttccat tttccattac aagccaagcc catccagaac caaatcgtcc agcggctgct
     8881 tttttgaatt cttctttaaa agaagaaaaa tcaccaaaag cttcattaat cgcttctttt
     8941 atttctcctg taggttcgcc accagcattt ggtgccatga tttcccagaa aaatgaatgg
     9001 ttagcatgtc cgccaccatt gttacgtaca gctgtcttga tatctgttgg aatagcgtcc
     9061 atatcagata ataattcttc tattgttttt tcgcctaatt ctgggtattt ctcaattgct
     9121 gaatttaaat tcgtcacata agtattgtga tgcttatcat gatgcagatg catcgtttct
     9181 tcgtcaatat aaggttccaa tgcgtcatat gcataaggta gatctggtaa tgtgtaagtc
     9241 ataaaaaaat tcctcctcaa tgttttctta ataatgtcta cattacaaag agtaacaaag
     9301 agaaggaaat tcttcaattg ttatgcctag tcgtcttttt cactttgacc tacttcttct
     9361 tcaaaaacct cagtttcttt aaaaataaac aacttgctga aaatatagtt cgcaaggata
     9421 acaataattt gagtgatgat tttcgccaca tactcattgc tgttcataac attgatcaac
     9481 aataccattg cccccatgtc caatccgtaa gaaaggatac ggtagaagaa gaacttaccg
     9541 cattcaataa gtgcatgtgt aaaattcggt gattttgaat ggaataccca aagtttgttc
     9601 gttacaaaag caaacaatac agaacaaaac cacgaaatag aattggataa ggccatactt
     9661 aaatcaaaat attggcgtgc gagagcaaaa ctaacaaaat ttacaatcgt agccaaacca
     9721 ccaaaaaaga gatagactag tatctcccaa tatccttttg cttctaaata tccttttaac
     9781 tgtcgatact gcttcatgag ccaacctacc ttattaaaaa ttcttattta tcatactcta
     9841 tatttcaata actttcatct ttatttaaaa aaattaattt tttttgatcc tttgcctttg
     9901 tctctgcttg gatcgtcaca tgtgtaatac catattttaa ttttaataaa gaaattatac
     9961 gaggatatat cttttcaatc tcgcttagta gctgatcttc aaaatcaata tgtccgtcga
    10021 aaataattat cttttcgcta tactgccaaa tatggacatg atgaacatcc tttaccccat
    10081 cgattgcttc aatttcttgt tccatttttt catagtcgat agcaggtgca ctttgtatca
    10141 aaatagcggc agcttttttg atcaccatta tcgcttctat caatatatat atcgaaatga
    10201 tcagtgtaat aactggatcg atccagtaga tatcgaaaaa acggatcaaa attgctccga
    10261 taatcacact taccgaagac agtgtatcac ttaacaaatg caaataacta gattttatat
    10321 tcaaactttc atctgcttct tgtcgtaata ataatactga gaacaaattc gcgagcaatc
    10381 caataactgc tactgttagc atcaaatgac tatttatctt ttctggtgaa gtgaaccgct
    10441 tgaatgcttc aacggttaaa aacaaggata atatgatcaa tatgaatgag ttgatgaaag
    10501 cactcaatat ttctaaacgc tggtagccat acgtacgttt tttatttgct tcttttcggg
    10561 ccattttttg tgccccgtaa gaaaaaataa ttgccaatgt atcactaagg ttatggaaag
    10621 catctgaaac aagagacaaa ctccctgaca taatccctcc aataaattct gataaagtga
    10681 tcaccgcatt caaaaccact actccaaata gtttttttga tgatctctgt ggctgtgtag
    10741 gcactattcc ttcctccatt ttatttatat tggatagtct ttagacaaga ataacatttt
    10801 tttgatattt caccaatcat tcagctgttt ccttaaagca cttgtatttc acttgatact
    10861 tcgctagaat tgcaagtgat gacactacta gatgaggagt acttatgaca acaaaacaat
    10921 taattatcag ttcctttata cgattcaaag acctaaagga gtcgagaaat gtcccatttt
    10981 ggaaagccat tgtctatctt ttagttttga gtataattat ggctttgcca atctcttttc
    11041 aagtttttca agtcttaaac aacattcaat tggatgggca aaagattgct actcgcattc
    11101 ctgattttac aatccaaaac gggcagcttc aaaccgaaga aaaagaagga ttcatttacc
    11161 aaacaaactc cattatcttc acatttgatc cagagggaaa acgaacagaa caggacatct
    11221 ctactgattt gatggggaat tttgttagtg tcgggatgtt aaaaaacaaa cttatcatag
    11281 ctcttcctaa tacaggcacg acttctgctt tgttgaacaa taaccaatta gaacttccct
    11341 acaccaatga atctttaaaa aacttaacag gtaagcagct ccgttctttt ttaagtgaag
    11401 catctatacc actttggata aaagtcctga catttatatt ttctatttat cctagttttc
    11461 tgaatctgct gatcactttg ctatttacca acattgctgc ttttctctat gcacgctttc
    11521 gactaacaaa agctactttt cttgattgtt taaaaacatt gatctattca atttcattgc
    11581 ctactataat tgcaacaatc ttgatggtct ttcttccttc ttttgacact agcgccttca
    11641 ttgcttttgc aggaatcttt atttttgctc aagctgtcaa aggatgggca aaaatatcga
    11701 tcaattaaga aataaagaca actcgttatt tctacttcaa tagacccttt tagaggttgt
    11761 gacatttttt tgtcacagcc ccttttttat ttgaaaaata tttctttctc aaaaaacaag
    11821 caaggcgctt caaagttctt cttgtatgcg ctacacttag agtaaagaaa ggcgggaaat
    11881 taactatgtc agaaagaatc atttatgcag atcgtccatt tcgtgatgaa tttatcgaag
    11941 aaatccatac tatagcgcct ggttatatct ttaaaacaga attacaacca gaggatctac
    12001 aaaatgtaga gatcagtttg ggctggaact cagactacca agaaaaacta ttagcctctt
    12061 ctaccttgaa atgggtccaa tctatctcag ctggtgttga tcagctaccc cttgagactt
    12121 tttcaaagaa acatatttta ctttcaaatg gtagtggcat ccacagtgaa tcgattacgg
    12181 agcatgtctt aggaatcatc cttgggtatt ctcgtggtct ttttcaagca caaaaggcac
    12241 agagtgacat gaaatggtta ggttcatcgg tccattacca atctatccaa gggaaaaaaa
    12301 tactaatcat tggaactggc catattggaa aaatgattgc aaaaaaatgc aaagcattag
    12361 acatgaactg ctatggaatc aatacatccg gtcatccagc agaaggaatg gaaaagactt
    12421 tttctttaaa tcaactaaag gaagttcttc ctgaagtaga tttcgtagtc aatatcttac
    12481 ctctaacgga ggaaacaact gggctctttg atcagcatat gtttgaacac tttgatccaa
    12541 aatctgtatt catcaatgtt ggccgtggtg cttctgttaa gacacaagat ctggtgcagg
    12601 ctttaaataa ccagcaactt tcctttgcag cattagacgt ttttgaggaa gagcctcttc
    12661 cacaagatca tcctctttgg aaaatggaca atgtactgat tacttcccac attgcaggtt
    12721 tgacacctga ttttcaaaag aaattaatgg ctattttttt aaccaatctg aaaagctact
    12781 ttgccaccca tgagcttcaa accaatcaag taaaattgtc tgcaggatat taatagctga
    12841 aaacaatatt ttcaaaagaa aaaagagaag gtgacaaaaa ttgtgtcacc ctctcttttt
    12901 ttattgtttt ttaaagtgat aggttggctc ctccaggttg ggatcataat caacaagtaa
    12961 atcatatcct ttaaagaacc attcatctgc ttcctcgata aaaaaaagtg tcccatcaat
    13021 ttccactttc tttacaggat gttctggctg ttcaactgac attccaatcg aaaaaccatc
    13081 atgaacctct gttttgccgt agacttttcc aaaaaaacgt attccgtaag tttctggcag
    13141 atcaatttct gagtcaaacc acttttgtgc ttttggcgtt accgttaatt tcatcccaac
    13201 aacctacttt ctcttttctt tctattgatt catcttatcg tctagaatat ccacatcgcc
    13261 tgtctctcca ataaccagta gattatcatt ttcacgaaca tattcatctg ctgcaggaga
    13321 agcgataacc gtttgatcta ctcttcgtat ggcgactact gttaagtcaa aacgttgcct
    13381 gaaatttaat tcagctaatg ttttgttgaa aaatttagga ttggagactc ggatttctgc
    13441 taaagaatat ttatctgaca actctaggta atctaaaata ttctttgaca ctaaattatg
    13501 cgcaatcctt attcccatgt ctcgctcggg atggacgacg cgatcagctc cgatcttttc
    13561 aagtactctg gcatgatact cattttgggc ttttgctaaa atatttggta cgcccatttc
    13621 ctttaccatc agagtaacta agatactggc ttgaatatct tctccaatag cgacaattac
    13681 atgatcgaaa tttcttatgc ctaatgatcg aagtgtcatt tcatcctgtg catttgccac
    13741 aacagcatga gtggctatat tcatatattc attgacccga tcttcattac tatcaatagc
    13801 cagtacttct tgaccagctt cgatcagtgt tcggcagata cttccgccaa atcgtccaag
    13861 acctacaatt gcaaaatttt gtttcaccgt tttcctcctt tagtatcttc ttttctcagt
    13921 ataacaaagc ctttacaaaa acaaaagcaa gcatcattat tgtaaaaaag ccaagaaaaa
    13981 taatagttat tttctcagct tttgattatc ctctttatca tcgtttttat ttcaccaaac
    14041 catgtttgaa tgcatagata gcggcttgtg tacggtcttc cacttctagc ttagccaata
    14101 tattggaaac atgtgttttt actgttttca gtgtaataaa caattcgtcc gctatttcct
    14161 gattactttt tccttcagaa atcagcatta aaatttcatt ttcccgattc gttagttctt
    14221 catgtaatac aggctcattt cgccgactca ttttttccat catttttgtt gtcacttctg
    14281 gttctaatac tcgctcgcca cgttgcgttg cccttatagc atcagcaatt tcatgtgcgg
    14341 tagaggtctt caacaaatac cctgctgcac ctgcttcaat ggcaggataa actttttcgt
    14401 catcaataaa actggttacg ataatgattt tagcttctgg ccaatctttt aagattgctt
    14461 ttgttgattc gataccatcc atttcttcca tgactaagtc cattaaaatg acgtccggtc
    14521 gaagtgtcat cgccttctca tagccttgtc gtccattttc agcttctcca attacttcaa
    14581 tgtcttcttg aatagataaa taagaagaga cgcctaagcg caccatttca tggtcatcta
    14641 ctaataaaac ttttatcatc cttatctatg cctccttcat caaagggacc ttgatttcta
    14701 cacttgtacc ttgaccttta aaactaatga tttttactgt tccaccaata ccagctactc
    14761 gttctttgat attgttcaat ccataacttc ccgttttcgt ttcattcata ttaaaccctg
    14821 ttccgtcgtc aataatacgt aacaaaagat tattgtctat tttgtgcaaa tatacctcta
    14881 attcattggc tttagcatgt cttaatgtat ttgataacaa ttcttgaacg attcggaaca
    14941 agtgatcctc aatggaacta gatagtttta catcttctac atcccatttc agcgaaatct
    15001 ggattttatt ttgcaattcc ttcaataact gctcgatacc ttgctttaaa cttttctctt
    15061 ctaaattgac tggacgtaga tgaagaagca gcgcacgcat ctcagactgg gaagcgttga
    15121 tgatctctgc taccattttc aactgcttgc gaaacatttc tggtgtctcg cttttttctg
    15181 cttgctccgt caatgccgac atcatcatca ttgctgcaaa caattgttgc gaaactgaat
    15241 catgcagctc acgggctaat cgatgtcttt ctaattctaa aatttcttct ttggtttgtc
    15301 catctacata ttggggacgg ctcgttacaa tttgtaattc actagatact tcaatcattt
    15361 tttcttttat cttagtgatt tccttatcaa tatctttgat gtataaatcg tccgatgcac
    15421 ttgggatcgg aagaagcaac aatttggatt cataattgcc agaagaaagt gcacgcagct
    15481 tttcttcgat tttcccgtat tttgtctttt gaataagtga taataataga aagacaatta
    15541 atcctacacc taaggaaatg gctaacaaat ggaagataag cggaacatat aataaacgtg
    15601 cacgcagtaa ttctccccac caatgacttt gattgctggc ataaaaataa gtgaaaagtg
    15661 aaaatagaat aataaggaaa gccgcaatcc ccgaataaac agctagcatc gctctggata
    15721 tttttcccat catattcgta tcacctcgac atctccaatc aaggtattag taataatctt
    15781 caatctacga gggttttcat cataatcact gctgtagatt ttgatttgtt catttttcaa
    15841 agaaaattgc tcttcttcaa acaagacatt tcctactaat gtcgcatgct ctaatcggat
    15901 ggctacgccc aaaggtacta agatccgtgt tctgcctatc ccttttctta caatcacaat
    15961 attatcatct tttggcaaaa gcgtattgcc caaatctatg atagtatcac cagaaatgac
    16021 ggcgatgttg atatcgtccc attcatagac gtcgtttcca atacgttggt taccgaataa
    16081 ttgctgtctt ttccgctcat tattatgtgt ttttaattgc tctgtttgga tcatcatgat
    16141 ctgtttcttt cgccaaaaag catttttggt taaatctatc cctgaaatct ctacaccttt
    16201 cagaccaata aataaaacgg caaatacagc catcatccat aaagcaggac tgttgactaa
    16261 gctaaaaaaa atgaccaaac ttcctaatat caattgaaaa ttttgaaatt tagtacgagg
    16321 atgtttgcgc atagctagat atatattgaa aataccgaat atcactaaaa gcaaaagtcc
    16381 agtattgttt acgatttgcc aaacagcaaa taacagcagt agtgcttcaa ctaccacaaa
    16441 aaaacgccaa gaactattca tcgctctttc tccctcctga cacattctca tttcatcata
    16501 cctatttttt taactgttgg ctataggact ttagatgtaa gatcgtttgt tgaaatctaa
    16561 aatacacaaa gagaaaaaga t
//
LOCUS       DAZULR010000053        16258 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.054, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000053 DAZULR010000000
VERSION     DAZULR010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16258
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.054"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            226..894
                     /locus_tag="ACG8ZV_002188"
     CDS             226..894
                     /locus_tag="ACG8ZV_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HFS4997473.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(1094..1414)
                     /locus_tag="ACG8ZV_002189"
     CDS             complement(1094..1414)
                     /locus_tag="ACG8ZV_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997474.1"
                     /translation="MGDCFCDGRTSQRYQKNEEEARKQPLPKQQMTLQEIDSILTEAF
                     LSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYFMIDHQPILWEDVRYIELKETKK
                     WFVT"
     gene            complement(1451..2833)
                     /locus_tag="ACG8ZV_002190"
     CDS             complement(1451..2833)
                     /locus_tag="ACG8ZV_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HFS4997475.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            complement(2989..4176)
                     /locus_tag="ACG8ZV_002191"
     CDS             complement(2989..4176)
                     /locus_tag="ACG8ZV_002191"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HFS4997476.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            complement(4183..5214)
                     /locus_tag="ACG8ZV_002192"
     CDS             complement(4183..5214)
                     /locus_tag="ACG8ZV_002192"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFS4997477.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            complement(5230..6684)
                     /locus_tag="ACG8ZV_002193"
     CDS             complement(5230..6684)
                     /locus_tag="ACG8ZV_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015486 -
                     glycoside-pentoside-hexuronide:cation symporter activity
                     [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside-pentoside-hexuronide (GPH):cation
                     symporter"
                     /protein_id="HFS4997478.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANVATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVVPSH"
     gene            6859..7764
                     /locus_tag="ACG8ZV_002194"
     CDS             6859..7764
                     /locus_tag="ACG8ZV_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HFS4997479.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            7855..8532
                     /locus_tag="ACG8ZV_002195"
     CDS             7855..8532
                     /locus_tag="ACG8ZV_002195"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008753 - NADPH dehydrogenase (quinone)
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFS4997480.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            8529..8699
                     /locus_tag="ACG8ZV_002196"
     CDS             8529..8699
                     /locus_tag="ACG8ZV_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997481.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            8813..9709
                     /locus_tag="ACG8ZV_002197"
     CDS             8813..9709
                     /locus_tag="ACG8ZV_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFS4997482.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(9764..11134)
                     /locus_tag="ACG8ZV_002198"
     CDS             complement(9764..11134)
                     /locus_tag="ACG8ZV_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFS4997483.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            11372..12118
                     /locus_tag="ACG8ZV_002199"
     CDS             11372..12118
                     /locus_tag="ACG8ZV_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFS4997484.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            12115..12954
                     /locus_tag="ACG8ZV_002200"
     CDS             12115..12954
                     /locus_tag="ACG8ZV_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFS4997485.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            12955..13905
                     /locus_tag="ACG8ZV_002201"
     CDS             12955..13905
                     /locus_tag="ACG8ZV_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HFS4997486.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            14046..14798
                     /locus_tag="ACG8ZV_002202"
     CDS             14046..14798
                     /locus_tag="ACG8ZV_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997487.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            14817..15968
                     /gene="queG"
                     /locus_tag="ACG8ZV_002203"
     CDS             14817..15968
                     /gene="queG"
                     /locus_tag="ACG8ZV_002203"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0052693 - epoxyqueuosine reductase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HFS4997488.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
BASE COUNT         5282 a         3021 c         3253 g         4702 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacggt tgtgtaaaaa tatcatttta gagcataaaa
       61 aaaaggagtg gatttctcca ctccaaaaaa gtctaacttt tgggggtcac tacagtgtca
      121 cagtcctttt tttagtaaaa ggatacattt cttccttgta tattccatgc gtgttcgtga
      181 gaaagcatat ataatttaat taacagatag ttagggggag aaaaaatgat tttttcaatt
      241 acaatgaaac tggtgttcgg gttgatcggt ttattattag tggtacgttt gcttgggaag
      301 aaatccatgt cagaaatcac accgtttgat ttagtctata cgcttgtttt aggtgggatc
      361 ttagaagaat caacctatga tgacaatgtc catgtagggc atgtcctatt tgccattgcg
      421 ctttgggcag taatgattta tggtatcgaa cgtatcgtcc aaaaaaatga aaaggtcaat
      481 cgttgggtca aaggcgagcc atctgttcta atcaaagacg gcgtcatcaa catgacagag
      541 ttgacaaata accatatcga gatggagcag ttgcgagcaa tcttaagaca gcaagaatgc
      601 ttttttcttg aaaatgccaa acatgttatc ctagagaatg ccggtcaaat gagtgtattg
      661 aaaaaatcag atgaagacaa agctttatcg atcctgcttg tagatgaagg gcaaattcag
      721 cataaagtgc ttcagtccaa tcaattgact gaagcatggc ttatggagaa cttgaagaaa
      781 gaaggctatg cagatgtaaa acagctgatt tatgttgaat ggtcagaaga aaaagggctc
      841 tacatactaa ataaagaaga cgtcatgcat gaatcttacc gaatagatgg atagatagac
      901 agaggttgtg aaatcagcgc cttggcttgt tactcaaaac taagcgactt tttcacaacc
      961 tctgatatct aatatacgtt gttccagaag ttgcttcttc gaaaaataag ccaaaattcc
     1021 acaaaaattt aagaagcaat tttcgaaaaa tcctttctta ttttttgaag ttgatcactt
     1081 ctgtcacaac ctctcatgtc acaaaccatt tttttgtttc ctttaactca atataccgta
     1141 cgtcttccca caatatcggc tgatggtcaa tcataaagta atcttcatag gcttcaccaa
     1201 tgaagtgccc ttcgacctca tccaagagtc ttccaaattc atcttttaaa ttgagctgaa
     1261 tgattactgc tttacgagat aaaaaggctt ctgtcagtat actatcgatt tcttgcaatg
     1321 tcatttgttg tttaggaaga ggctgtttgc gtgcttcttc ttcatttttt tgataccgtt
     1381 gactagttct tccatcgcaa aagcagtccc ccattttaat ccaaatggcc gatctcgata
     1441 ctcgttatag tcaatgaatt tttttgctgt ccgtctcatc ttttccacct tctaatccac
     1501 tcataccacc tgcatgcccg ccaacgagag aactacgtgc gatggcgcgt cctccttgca
     1561 agagactatg cgcatggatg attgattgaa agccgtattt ttttctaatc gtatcgacaa
     1621 caaaatcaac tttcgcttca tttatctgct tttcaggatc ttcaaaaagg ttaagctgta
     1681 aacctgtcgc gtatacgagg tcggaacagt tcacgcctac acgccgaata tcctggtagt
     1741 ggtaatgctg gtggaaaatg gtcaataaag catctgctag atctctgcta gcatttgtcg
     1801 cttcgatttt catttgctgg tgaaacccgg tcttgccatt tggatcaaga tagcctaaag
     1861 agtatcctac ccataagctg actacttgtg tttttgctgc agatcgtctc aagcgagtgc
     1921 cgacttggtc ggccatttct ttgataacga tctcgatttc ttctcgtctt gtataatctc
     1981 tatctaggat ttgactattt ccgatacttt ttgattttgg tgtatattct tgtcccaaaa
     2041 aacttcgatc gatgccccaa gcatgggcat aaagctgagt accgatgacc cctagcttgc
     2101 ttttcaagtg ataataatcc gcgtgagcta aatcataaac agaatgtata cccatttgtt
     2161 tcagacgttt tgctgttcgt ttgccgattc cccaaaagtc agtgatatct gagattttcc
     2221 ataacttttc tggtacatct tcataacgcc attcagcaaa catttgcttt ccgtcttttg
     2281 agccattgtc taaggctagt ttagcaagta gcgggttatc gccaattcct atagtcgtgt
     2341 agattccggt ctgctcaaac acatctttat ggatcagttt agccatgtcg tacgcatttg
     2401 ttttaccaaa gagtgccatg ctatttgtta catcaaggaa gctttcatcg acggaataga
     2461 catgatggtt cgcttcgtct gcatattttt tatagataga attgatttct ctgttctttt
     2521 ccatataata ggccatcctt ggggcaacaa tatataaatc acttggatag gggaagggaa
     2581 gatctctggc acggctgata ttggtgatgc cgtaagcttt ttttgctgca ggactggaag
     2641 ccaagattaa tccgctaccc cgtgtttctg tcgaatcgga cggataggac atgactacta
     2701 atttagttgt aaggggatca agatcctttt caacgcactc tacggaggcg taaaaagatt
     2761 tgcagtcaat acataaaata tctcttgaag gttctttttc ataaacaaat accggatttt
     2821 gattcgccca cataacaatc acctcttcaa cacaattaga acacacgttc tctttccgtg
     2881 tcaataaaaa acagcaattt tcaaatacga gcaaaaggct cacatttgga aattgctgag
     2941 aggttatttt tatctatttg tttttagctg agatcgttga tttttttatc aaacatgaac
     3001 agcttctgga tcgatctttg ttgtcccatt tccaatgtgt gcaacataaa attccggagc
     3061 atagccgaca actttcatgt attcatcata gacattgttt ttgaaggcag gtatattttc
     3121 ttctttgaca agagcaatcg cacagccacc aaatccagct cctgtcattc gtgcacctaa
     3181 gacaccttct tgtttttgag cagcatctac tagtgtatct aattcgatcc cagttacttc
     3241 ataatcatag cgaagagagt ggtgagaatc atttaacagt tgaccaaatg cttctaagtt
     3301 cccagcttct aattcagctt ttgccttcaa agtccgctga ttttcagaaa cggcatggcg
     3361 agctctgcgt atcaatgtat catcgccgat ttggtcaata gttgattcaa attcttcttc
     3421 atctaagtct cctaaagaag agataggcaa agttttttgc aaacgtgcca aggcttcttc
     3481 gcattcgcta cggcgttcat tgtattttga atctgccaat tcccgccgct tattcgtatt
     3541 catgatgacg attgcataac catctagttt cactggaacc atttcgtatt tcagcgtatt
     3601 tgtatctaat aagattgcat gatctagctc accgaagccg atggcaaact gatccatgat
     3661 acctgaattg acaccgatga attcattttc tactttttta cctgtttgga ctagttccaa
     3721 gcgatctgtt tttaaatcaa acagatcttc taatacaaca cctactaata attctaatga
     3781 agcgctactg gaaagtcctg caccattagg gattgttcct tccactaata actcaaaccc
     3841 atgatcgatt gagtgtccag cttcttttaa tttaaggacc attcctttta cgtaatttgc
     3901 ccagtttgct tttttatcat attctagctc atctaaagta aaactaatga caccgatatc
     3961 gtcaaagttt gtggaataaa ctaatatttt attatcgtct cgaggtgctg ctacaccttg
     4021 cgttccataa gtgatggaag cggggaagac atggcctcca ttgtaatctg tgtgttcacc
     4081 aatcaaattg atgcgtcctg gtgagaagta ttgtgtagtt tttttaggtc cgaatgtttc
     4141 ggcaaatttt gtgtttaagc ttcttttgat ttccatgatg agttattcct ttcttgtttt
     4201 gattttgaat tctgttactg tttcaaatac tgatccggct tttaaatgaa tcgaaccaaa
     4261 tgctgagaag cgctctgcac ctggagctgt ttgagtctca aatgtgatgc caccgtgatg
     4321 tgccagtttt cggttgcgca tttctggtgt ttctgtgccg aaatttgcag tgaaaataac
     4381 cacactagaa gcatctgtag caatatctac ttggattctt ttatcggggc tagtcaagcg
     4441 agcggcttct ttacccaagc cggtttcttt taagaaaaat ggatgatcga ttccgtcaac
     4501 aagatttttt tgatccaaat cactagcaaa aacggacgct aattttttag gtatttgaaa
     4561 atcgaaagca cttcctgcag cattttcttt tacccctata ggaatactat ctgttcgcaa
     4621 aggagcataa gcttcgctat tgagccaaag ctcatgttga tcgattgact gagaagcatc
     4681 tcccgtcaag ttgaagtaaa catgatttgt cggattgaat aaagtatctt ggtcactggt
     4741 gccgcgagag gtcactcgcc agatattatc ttttgtcaaa gtatagcgga tttccacatc
     4801 cattgtacct ggaaaaccat gttctccgtc gggacttgta gtagtaaaaa tgacagaagc
     4861 ttcattttcg ccattcaaaa tgacataaga ccattttttt aattcaaatc caggagcacc
     4921 accatgcaga ttatgtccag tttttggatc tgtggctaat tggtaagttt ttccattgag
     4981 agaaaagcgg ccattttcga ttctccctgc ggtgcgaccg atagaagcac cgatatacgg
     5041 atctttttcg atatattctt cagcggtgtc aaatcccaaa actaattctc gatcatttga
     5101 ttttaaactg acgattctag cacctaaatc agagatagaa agtgctagct tgtttttgtt
     5161 ctccaaggtt atcaagtgat aaccttggcc aaaatctttt tctgtaatct tcattttcaa
     5221 gatcctttct taatgggaag gaactactgc atcgtgaagt tcatcttcca ttgtatcagc
     5281 tggagccaat ttgttttcca atttctcaac gatttgtgca tgttttttct ctgtcaatgt
     5341 aatcttccaa gcaaaaataa tagcggagaa aatcatcaaa gcagcaggag catagaatgc
     5401 ataagctttg aaagtcgtta cgccatgagc agtgatatca gcagcagtag cattaccagt
     5461 catcccagaa gcgatagcga caaaccctac gatcccgtta gacaaagcac cagcgatttt
     5521 atctagtaaa gggcgaattg atagagtaac agcttcgtta cggataccat ttttccattg
     5581 accatattca acagagtctg tgatcgtcat caaagcggat aagaaaatca attgttgagg
     5641 gaagtagaac aatactagcc cgatgataac gattggcaaa cttgaacctg cgatcgtaaa
     5701 gaaaaagtaa gaagaaatca tcattgcgat ccctccaagg taaacgtagc gacgagagat
     5761 gacgcgtgta agcattggga atagtggaac agctactaaa ccaagtaagg cagcaactag
     5821 accaacgatc caaaattcag ttggttggcc aagtacatat ttgaagaagt agaataatac
     5881 ggcagttgtt gctacattgg caatcgcata agcgatataa gcaagggcaa gccacatcaa
     5941 ctgatcattt tgagcaactg ctttgaacac atctttgatc ccagcttttt cattttgctg
     6001 acggatcgca gtatcgactt cttttgtgcc caaggcagtg ataatcgcag taccgcctga
     6061 aataacagca gcaatcacac cgaaccagaa ccagcctgaa gcgccttcaa tatgtttatg
     6121 agtaacaaga taggtaaaga aagtaacgat agggacaacg actagagtag taccatttgc
     6181 acctagagaa gagccgaaac gagcaaacgt agcaaatttt tcacgttcct ttgtttccgt
     6241 actcaaagct ggaatcattg accaaaaagc gatatcctta aatgaataaa aactatccaa
     6301 taagatgaaa acgattgcaa ataatatgat aaataaagtc gtattatgag tagctaagcc
     6361 aaagaaattg gtaaagattg ctaccaagag tacggaacta acaacgccgc cgataactaa
     6421 ccatggtttg aatttaccgt attttgtacg agtattatcg atgatgccac caatcaaagg
     6481 atcaaaaata atttcaacta agcggatacc tacaactaag cttgtaactg tagcaatcat
     6541 ttttgcattc gttgccttat ctgttcctgc gaacatctgg cttgtcacga ataccataaa
     6601 ataagtgctt aatgtaacat agaatgtgtc gtgtccaaaa gcgcctaaag cgtaggacac
     6661 acgttggatc attttgcttt tcataatctg tattcctctc ctgttcaata tataatacta
     6721 agtaaaccgg ttacaacgaa taacaaagat cttttaatga cttaaactta acaagaaatc
     6781 gcttcctttt taatatattt ctgtgacttt tatttaactt tttgttgcat tatactaaag
     6841 gagtaaggag ggatagacgt ggagcaatcg atttttttaa aaaaggaaca tcaacaagta
     6901 gaaaaagaat tgtattttga tttttgtggt ttctctaaaa cgatgccgtt tcattctttt
     6961 ggtcctgcta ttcgcaatga ttacatcctg catgtcgtga tggaaggcaa aggatcttat
     7021 catgtgaaaa atcaacaatt ccaattgaaa aaaggtgatc tgttcttgat tcgtccagga
     7081 gactcgacgt tttacttatc agatggagaa gatccgtgga tgtattgctg gctttcattt
     7141 ggtgggagtg ctgcagaaga aatcattcgg cagtcgcttt tcagagaaga ccaatacacg
     7201 atggtctctt ctgacataca aaaatatatc gacattattt tagaatgcat gaaagatacg
     7261 gaagaaacct tggaaaatga attacagtta acagcattaa cctaccgttt tttatcagtc
     7321 cttttaaaag atggcggaaa ggtcagcggt ggtgtacaaa aggttcattc ctctttagct
     7381 gttgaaacag tcaaatacat cgaggcacat tatgctgaaa aattgtctgt tgaggaaatc
     7441 gcccagcatt tagcggtcaa tcggagccat ttgtcgcgag tattcaaaaa tcatatgggt
     7501 accagtatca aggaatattt gatcggggta cggatcaatc gaggggcgtt tcttctttct
     7561 ctgacggatg aatccgtgga aagtattgcc tatcaagtag ggttcaatag tctagtcgta
     7621 tttagccgaa tgttcaaaaa gagtaccgga gaaacggcta cgaactatcg taaacgtatg
     7681 aaaaacgaaa attttaagaa tattgctttg gataccttga aaaaacagtt ggaaaaacaa
     7741 accgcagttt cttggacaac ctgattagtc tggttaaaat gacaagcatc ggcaaaagaa
     7801 acttgtggcg gttatgctac actgtaaagc gaagactaaa aaggaggaaa agggatgcgt
     7861 acacttatca tcattagcca tccaacgatc gaagaatctt taaatcagca atttttcaaa
     7921 gaagcttctg ctggtttacc agctacttgg catcatttgg aatcaagtta tccagacgga
     7981 aaaatagata tagagactga actacagctc ttggcccagc atgatcggat cattttccag
     8041 tttccgtttt actggtatag ttctcctgct catttaaaaa tttggcaaga taatgtcttg
     8101 gaacgagcag cacatgtatt aaaagggaaa gaactaggaa tcgtattgac aacaggtgtg
     8161 gcggaaaaag aataccaagc tggaggaaaa gaagaatata cgatttccga atttttgagg
     8221 ccgtatcagc gaatcgcaaa taaattccat atgacctatc ttccgccatt cgttttagca
     8281 caatttatgt atttatccca ggaaaaacgt tgggagaagc taattgctta tcagcagtat
     8341 ctctcattgg aaggcaaacc atcgctgact cagcggattg actggtttat tcaaagagta
     8401 caggaaaatc agaaaatgca ggaagaagaa tctgaaaaac aagcatatat cgtagaagca
     8461 ctgactgagg caaaagagca gatcgaagac ttgaccttta cactgcaaga aatgaaagga
     8521 acttcattat gacaaatgat tggctgatcc aacaattaga tgaattaagc gaaaaatcag
     8581 aatatcaaga ccgtgcgctc ttatatgaaa taaagaaact gatggctgag atagacgaac
     8641 gaacaatgca gctgcaagga gaaatcgacg gacaatcttg gaatcatctc aactggtgaa
     8701 attttcttat aaataacaaa gataaaaatg tgcacagcga caattatttg ctacaataag
     8761 aatatgaagc gtttgataac gctattatac ataaaaattg gtggtgaaaa aaatgtatga
     8821 tgaaaatgag tggggagaaa atgttcggat gacccgaaga agacagcaaa aacaggcagc
     8881 tcgtaagcgg atgatcatga ttggggcagc agttgccgtg tttttgatca tagcaggagg
     8941 agttgcgggt ctatattttc atggaaaaaa ttcgtcagaa gcgaaaagta cgaccataac
     9001 ggaaacaacg acaaagaaaa cagagacgaa acaaacaagt gagtcatcaa ctaaaacaaa
     9061 agagacacaa acttctgaag aaaaaacagc aaatggtttg ccagagcaac ttcaagcaat
     9121 cgtaaatgat tattcgaaaa agatcgaaga aaagacgcct gcattgattg aagaatacca
     9181 gacagaaatt cagggaaatc aagagggaat agctggttta tcagcagttg ctaaccaaaa
     9241 agcacgtgag cttcaagcaa tctccgacga agggatcaga aaattacgtg cagcgtatca
     9301 ggcagcagaa aataaagacg gtgtagactt agatactttg atcaatcaat tatcggctaa
     9361 ttatacgaat catgtcgcta agatttccga tatttatttg cagactagcg cctctcttca
     9421 agcagagtca acaagcacac aagacacaac atcttctgat tctgagacag cagagtcggt
     9481 agaagcttct gaaatgcaag ctcgaacaac acaagacaca acagattcct ctgaaactaa
     9541 taccaacagc gcgacttcac aggctgcgac aaccgtagtt ttggaaggag aaggtccaaa
     9601 tcaaatagcc gaacgaactg gcgtaccagt agaaacgatc ttgtcgctga atgggatgag
     9661 catggagaat tatttcctga ctcccggtga gacgctaaaa ttgaattgat aaaagcaata
     9721 aaaaagaacg aagcttccac taaggtgaag cttcgttctt tttttatttt ccggttcttt
     9781 tttcgcgtac aaagtaatgg atcgtcatgt aaagcaagaa aacgagtcca ataatcaatg
     9841 agattctcgt ttcaggattg ataaacatga aaatcaatac gatagctaaa aaagcaagtg
     9901 tcacataatt cgtataagga gatagtggca ttttaaaagg atgatcatgc attttatctg
     9961 cgtgcttctt tttgaagcga atctcgctga tcaaaatcac tacccaagga accataccag
    10021 gcaaaatact tgagctgtat acgaaaacga aaatattttc tgactggttg atgaacattg
    10081 gtagaagata atttaagatc agaccaatta agattccacc tgagattgct acgacaggat
    10141 aaaaaggcgc accgtgacga gatagtttca gaaatttttt agacatcttt ccatttatgg
    10201 caagtgtata gaccatacga cttgcgctga aaatccctga attgcaacct gataatgccg
    10261 ctgtaatcac gacaaaatta atcagtcctg cagcaaatgt aatgccgact ttagaaaaag
    10321 tttgtacaaa aggtgaacca atctcactca attgattcca cggatagata ctcacaatga
    10381 taaaaatagc accaatataa aaaatcaaga ttcgaccgat agtggactgg acagcttcaa
    10441 tgatcgtctt tttaggattc tctgcttcac cagcagtcat tccgatcagt tcgattcctt
    10501 gataggaagc aacaacgatc gataatgcaa agaaaaatcc tttgacgcct ccagtgaaga
    10561 atccaccatt tttccaaaga tttgaaatcc ctactgcctg accatgatta ccaaatccaa
    10621 ataagattac cccaagacct gcaatgatca tcaaaatgat cgttatgact ttgatgatcg
    10681 aaaaccaaaa ttctaattcg ccaaacgcct tgacagaaat aagatttgcc agcataagaa
    10741 acaagacgac aatgattccg ggaataattg ccggcaaatc aggccaccaa taattcatat
    10801 aagatcctac agcaatcact tcacttattc ctacgacaat atattgaaaa atattactcc
    10861 aagcggtcaa gtagccagcc acaggatgga tgtactcgct cgcgtaattt gcaaaagaac
    10921 cagtcgaagg atcaacgtaa agcatttcgc ctaaagcacg cataatcaaa tacaaaaaga
    10981 atcctgcaat cgcataggct cccatcactg agggccctgt ccaacgtatg gttgaggagg
    11041 cacccataaa cagaccgaca ccgatcgttc cacctagtgc gatcatttgg atatgacggg
    11101 cactaagact tcgagttaac ttttcttctt ccatacaaaa actcctttcg ttgttgagtc
    11161 aacaagaaaa aataatcaaa cgtttcaaca catgtttttc attattaggt tagccttatt
    11221 gaactcttga tgtgattcta cagaaaattt tcataaaatg cgaggaaaat tcgaaaaaaa
    11281 ctttttcatc attctacttg aaaatgcttt ccattttagt taaactatat ttaaataaaa
    11341 agttaggtaa acctaaaaag gagtgtaaga tttggaacgt acggccattg taattcaaga
    11401 cctttcagcc gcttatcaag ggaaaactgt tttgaaaact atcaacttga cgataaatcc
    11461 acaaaaaatt accggtatta tcggaccaaa cggtgcagga aaatcaacat ttatgaaatc
    11521 tttgctagag ttgataccag ctactactgg taaagtcacc ttttctggac agtcggtaaa
    11581 ctcagtccgt aaaaaaatag cctacgtgga acagcgaagt gaattggatc tttcctttcc
    11641 aattgatgta ttaggcgttg tacttttagg aacatatcca tctttacgaa ttggacaaag
    11701 acctgggaaa aaagaaaaag aacgtgcaag acaagctttg aaaaaagtag ggatggaaga
    11761 atatgccaaa agacagatca gcgaactatc gggtggacag cttcagagag tttttattgc
    11821 aagagctcta gcccaaggag cagaatggat ctttttagat gaaccattcg tagggattga
    11881 tgcgttaagt gaacgaaaga tctttgacat cttgcaggaa ttgaagaatt caggaaaaac
    11941 gattttgatc gtccatcatg atcttcataa agtagaagaa tatttcgatg aggttattct
    12001 tttaaataaa cagctgatcg cttccggtcc agtacaagaa gtctttacat cgaagaacct
    12061 tcaattggcc tatggtgaga tcatcagaca tttagtaaaa ggaggagaga aaaaatgatc
    12121 caatccttta ttgatggatt aatgaattat caattcctgc aatacgcttt ggtcacttcc
    12181 atgcttgtag gacttgcttc tggagtcatc ggttctttta ttattttacg agggatgtct
    12241 ttgatgggag acgctatctc tcacgcagtt cttccaggtg tagccatttc ttatatgttt
    12301 ggttttagtt acatctttgg agccactgct tttgggatgc taacagcagc agtgattggt
    12361 ttcgtgactc agcggagccg attgaaaaat gatacagcga ttggaattgt ctttagctcc
    12421 ttttttgcat tagggattat cttgatttca tatgcccaga gtgcgacaga tttgtatcat
    12481 attttatttg ggaatgtctt agctgttagg gaaagcgatt tgttgctgac agcactcgtt
    12541 agtggaatcg tcttgatatt tgtctttttc ttttataaag aattgaagat cacatcattc
    12601 gatccgacaa tggcaaaagc ttatgggctg aacacatcgc tgatccatta tcttttgatg
    12661 ttctttttga cattagtggc tgtagtcagt ttacagacag taggaacaat cttggtgatt
    12721 gccatgttga tcacaccagc cgccacggct tacttgctaa cgaaccattt actgaaaatg
    12781 atcattacag ctgcaggaat cggtatgcta agtgcagttg tcggtgtgtt tttcagttat
    12841 agttacaatt ggccatcagg agctacgatc gtgttagcat gtaccgcatt ttttatcctt
    12901 gcttttttat tttctccaac aaaaggaatt ttatttcaga aaggaagcag atagatgaaa
    12961 acaaaaaaat cactcttttt aatcttggca gttagtttct tggtattagc cggttgcgga
    13021 aagcaggctt ctgaccaagc ggatgaagga agtaaagaaa agttgtcagt cgtggctacc
    13081 aattcgatct tggcggacat ggcaaaagag gtcggaacag atcaaataga tatccacagt
    13141 atcgtaccag tcggaacaga tccgcatgaa tatgaagtac taccagaaga catcaaaaag
    13201 gcaagcgatg cagatgttat tttatacaac ggtttgaatc ttgaaacagg taacagctgg
    13261 ttcgataact tgatggaaac ggctaaaaaa gaagaaggaa aagattattt tgcagttagc
    13321 aaaaatgtag aacctcttta tttaactagc ggtgaagaac atacaaaagc agatccccat
    13381 gcttggctag acctatctaa cggaataaaa tatgtggagg aaatcgcacg tatattctct
    13441 gaaaaagatg cagaaaatgc gacactctat aaaaaaaatg cagaagcata tgtggaaaaa
    13501 ctaaaagaat tagatacaca agcgaaggaa agttttgctt ctatcgaaga gaacaaaaaa
    13561 ttattagtaa caagtgaagg ggcattcaag tatttttcac gagcatatga tttgccagca
    13621 gcttatatat gggagatcaa tacagaaagt caaggtacgc ctgatcaaat gaaagcgatc
    13681 attgatcaga taagagcaaa agaagtaccg gttttattcg tggaaaccag tgtagactca
    13741 agaagcatgg aacgggtagc aaaagaaacg ggtttgaaaa tctatgataa actgttcact
    13801 gattccatag caaaagaagg agaacaagga gattcttact atcagatgat gaaatggaat
    13861 attgaaacga tccatgaagg tttgtcacaa acaaaagaaa gctgaaaagt gcaaggtcta
    13921 gcttgaggag cagaccttgc attttttata agagatatga aaaaaaatta tgctgttttt
    13981 cgtcgtacag ataccttttt tgaagaaatt ccgttatagt tagagtaagg aaggaaggtg
    14041 tggctatgaa ttttacacgt aaagataaat atacgattaa agaagaagtc tttcgattga
    14101 tcagccagca ggaaaatacc gacaaggatc aagaccttca atttcttgaa gcagaattag
    14161 ctaaattatt catagcaaat caaaatgaga caacagaacc agatgaagag ctgtacatag
    14221 gcaaatggtt gtttgatgaa tttcagcctt tagatgaaaa taccggtatc ggttattttg
    14281 tgttcctttc tccagtcggc ttcacacctg gcgtattagt taaacaaaac gacgaaataa
    14341 ccgtcaaagc atggcctgca ttattttcag tcatcaaagc agaaggagta atcaaaaaga
    14401 tccagtcggc ctattataaa agtcaattta ttgccaacag caaattaatg aatatgtttt
    14461 ataatcgtct agtagaaatt gctaggcctg ggaaaatccc gcaaacattc acgtacacac
    14521 agcaaaaaaa tctctatgaa gaagtattgt attcccgcga tctgtctgag ttttcgccat
    14581 gggaagaggt aaggctccat gaactgttaa gtacaaaacc agtttcattg aattttttta
    14641 atgcattaga taacaaaaga aaattaattt caacaaatta ttgggaagta tttgctgcaa
    14701 gaaaaaaatg gatggaagaa aagaagattg ccgatcagca gatccagttt gtccagctga
    14761 aaaaagaaaa actatattat gggttataca gccgttaaca gcaagcgagg aagaccatga
    14821 cattaaaaga agaaatcata caagaaagca aacgattagg aattgacaaa atcgggttca
    14881 ccacggcgga accttttgat tcattaaaag aatcgttgga agaacaaaaa gcagctggcc
    14941 atacttctgg ctttgaacat ccaaatatcg atgagcgtct ttatccagaa atgacatttg
    15001 atcagccgaa atcgatcatt tccattgcac ttgcgtatcc tactaggatc catgaagaag
    15061 tgcctaggga tgaaaaacgc gggcagtttg ctcgtgcttc ttgggggatc gattaccatg
    15121 atatactcag agaccgtttg aaccgattga tcgaattcat ccaaacaaga gcagaaaaat
    15181 ggcaaaaaga agaggaatgg cgtctagctc cgcaagtaga tactggagaa ctgatcgatg
    15241 tcgctgtagc acagcgagct ggtttaggat ttattggacg aaacggattg ttgatcactg
    15301 aagagttcgg ttcatttgtc tatcttggtg agatcgttac taatattgta tttgagcctg
    15361 ataaaccagg agaatttggt tgcggtgact gtatgcgctg cgtgactgct tgtccgacaa
    15421 aagcattgct tggtgacgga agaatgaatg cccagcgatg tttgtcttat caaactcaga
    15481 caaaagggat gatgccggaa gaatatcgta aaaaaatgcg aaatgtcatt tatggatgtg
    15541 atatctgcca gttagtctgc ccttacaatc aaggaaaaga ttttcatttt catgaagaga
    15601 tggaaccaaa agtagacgaa atatatccaa aattaaagcc aatgctttcg atgtctaata
    15661 aagacttcaa acagcaattt gggcatttag ctggttcatg gcgtgggaag aaacctttgc
    15721 agagaaacgc attgattgct ttagctaatc taggtgatcg aacggcattg cctgagattt
    15781 cagaatgttt aacagatgtc cgccctgtca tcagaggaac agcagcttgg gctattggac
    15841 gtctaggaac aaaagaaccg gaaaaatggc ttgatgtatt agatgaaata ttagctaaag
    15901 aaacagaaga agtcgttata aacgaattgg aacatgccca gaaattattg cggagaaagt
    15961 taaaataaaa aaatagttaa cattattcaa agtttttgtc cagtaattgt tgtaacaatt
    16021 actggttttt ttgtattttt tacatttttt taagagaatt tgataaaaat caaaaatttt
    16081 tttgcttttt tttatggatt attgcagtga atgttacaga atctgcgttt ttcattcaaa
    16141 aataaaaaaa catagaaaaa cgattacttt gcttatacaa caaggctttt atggttttgt
    16201 atcaaaaaaa tatttgttta aatgttacaa atattaaata attcgttatt ttgtcatt
//
LOCUS       DAZULR010000054        15932 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.055, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000054 DAZULR010000000
VERSION     DAZULR010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15932
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.055"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            133..3660
                     /locus_tag="ACG8ZV_002204"
     CDS             133..3660
                     /locus_tag="ACG8ZV_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HFS4997489.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3657..7379
                     /gene="addA"
                     /locus_tag="ACG8ZV_002205"
     CDS             3657..7379
                     /gene="addA"
                     /locus_tag="ACG8ZV_002205"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HFS4997490.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7448..7789
                     /locus_tag="ACG8ZV_002206"
     CDS             7448..7789
                     /locus_tag="ACG8ZV_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFS4997491.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8098..9141
                     /gene="pheS"
                     /locus_tag="ACG8ZV_002207"
     CDS             8098..9141
                     /gene="pheS"
                     /locus_tag="ACG8ZV_002207"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HFS4997492.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9146..11566
                     /gene="pheT"
                     /locus_tag="ACG8ZV_002208"
     CDS             9146..11566
                     /gene="pheT"
                     /locus_tag="ACG8ZV_002208"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HFS4997493.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="ACG8ZV_002209"
     CDS             complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="ACG8ZV_002209"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HFS4997494.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            13000..13737
                     /locus_tag="ACG8ZV_002210"
     CDS             13000..13737
                     /locus_tag="ACG8ZV_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFS4997495.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13751..14566
                     /locus_tag="ACG8ZV_002211"
     CDS             13751..14566
                     /locus_tag="ACG8ZV_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFS4997496.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14579..15226
                     /locus_tag="ACG8ZV_002212"
     CDS             14579..15226
                     /locus_tag="ACG8ZV_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFS4997497.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSTLAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15242..15898
                     /locus_tag="ACG8ZV_002213"
     CDS             15242..15898
                     /locus_tag="ACG8ZV_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFS4997498.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
BASE COUNT         5342 a         2745 c         3377 g         4468 t
ORIGIN      
        1 tttttgcgta tacttaaaaa agtagaaata tcagaacctt aaaaggatat aatttgaaga
       61 atatagaaca aatgttcagt attttttgat ataataaagg agcaccgtat catgtgttga
      121 aggaggaaaa gcatgtcttt acaatttatt cttggaaacg ggaaaaaaga tcaccgtcaa
      181 gtcttgatcg acgaagcatc cgcttggctc gaccaggatg caagtaacca agtatttttc
      241 cttgttccca actacagcaa attcgaacag gaacaagaaa ttttagcgga gatgcgaaga
      301 agaagcggaa aaaaaacttt cagcacaaca aacgttcaag tatttagttt ttatcgtctg
      361 gcttggtatt tgctgcaaca gacaactctt cttacaggaa atgaattatc agaatcagga
      421 tctgcaatga tcttgcgaca gattttagaa aaaaatgagg aagaattaac aatctttcgc
      481 ggagaaatca ataaaagagg gtttattcgt caattacaag aactctacag tgaattgcgt
      541 acaggaaata ttcaaccaga agacctgatg cttttatttg gtgattcacc taatgcagaa
      601 gaccagcaac ttaaaatgaa agacttgaag ctgatttttt cagcttatga cagcgaattg
      661 actcaacgtg cactaacaaa tgaagatgca ctatctatac tagcaaatta tatgcagaca
      721 caagatttca acaacgtcaa atttattgtc agtggttttt ctcgaatcaa tggtcaagag
      781 tatcaattac tgcaggcaat gatggaaaag gggcaattgg ttgtcgattt attgctggat
      841 cgtccttata cagcggatct tccagaagta cttacgctct ttcatgagac tggaaagctt
      901 tatttccgtc tttttcaaag tgcaagagaa cggaaagtcc ctatattagt ggaccgattt
      961 gcaccagagc agactcgtcc gacagagctt caactgctgc aaacaatgtg ggaagagaca
     1021 tctagccaaa agaaagcggc agtacacaaa atagggggac aagagcatct ccatttgtgg
     1081 gaagctgaaa atccaactga agaagtccga caattagctg ttgaaatcag acgactagtc
     1141 agtgaagaaa actaccgtta tcgtgatatc caagtgctga caaaaaatat gtctttatat
     1201 ggaaatatcc ttcggccgat ctttcaagaa atggcaattc ctttttatat cgatgaagaa
     1261 caaatgatgg aaaatcatcc gctgatcgaa tggatcaaca gtctgttcgc tcttgaccgc
     1321 tattcttatc ggctaagtga tattatgcgt tttttcaaaa ctgaattatt tctgtcgacg
     1381 gaagcagaaa ccgaacttga tgaatggaaa caagagcgag atgaattcag gaaaaaactg
     1441 gacatcactg aaaatgtagc acttgcttac aattatcaag gaacttattg gactcgtgaa
     1501 aaagactggc agtttgtggc gtatgatttt gaagcagaac agattgaaga cgtacagtat
     1561 ttggaagaac agtcaaatac gattagacga ttatttcaga aagctgtacc agtatttttg
     1621 aaaaaaataa agaaaagcaa aacaggacaa gaggccgcaa atgtttttta tcaatttttg
     1681 atccaaagtg gcgtacagca acaattattg ttttggcgta atcaggaagt agacagagga
     1741 aacttagaag cggcaagaaa ccatgagcag acatggggag cgctgattga tctgttggat
     1801 gaatatgtag taatttatgg tgaatcggct tttgactggt cactgttcca agaaatcatt
     1861 acaagtggtc tagaaaatct aagttatggt aaaatcccta ccgcaatcga ccaagtgcga
     1921 atcaatcgtt tggaattagt tcgaccaaat caagctgccg tcacttttgc attagggttg
     1981 aatgatcaag tgtttccaga ccgaaaagag acaaaaggat tgttgtccag tgaagaacga
     2041 gaagtattaa atcaggcctt gccagatgga cagtttttat tcgacccatc aaaggaaagt
     2101 atctcttttg agcctttcca agcctatctt gtttttcttt ccggaacaga tcgattatat
     2161 cttagttatg cacaaagcta tgacacagat ggttcgctga agatgtctcc ttatttgcgt
     2221 agaatcacag aatatttatc tgttcccgtc gagagaaaag agcatttgac gatcgaaagc
     2281 gaccctaatt gttatgtagg gacttacaga agcggaatca atacagtcaa taggatttat
     2341 cgattagctt tagatgaaaa aaaacctgta ccaaagcact ggcaaaagct caaagaatta
     2401 gtactgaatt cgtcatggcg aaattttgct ttacagattt ttgaaagtca ggaacattta
     2461 aatgttcctg tttcgatgcc agaaaaaatg gcggaagagc tttatggaaa agagatttat
     2521 acttcaattt cacgtatgga gaatttttat aattgtgaat acaaatactt catgcaattt
     2581 ggtttgaaat tgaaagaacg aactgtttat ggtctaactc cagcagcaac tggtgatttt
     2641 tatcatgaat cattggatcg tttcttcaag ctactgtttt caaaccaatt atccttagtg
     2701 aatatgtccg atgcgcagcg tagagacttt actgaaaaag tgctgcagga agtattcgga
     2761 gaacttcggt ttgagatatt ggatagttct gcaagaatga actatatccg ctaccagtta
     2821 ggacagacga ttcaaaaagt gacatgggct ttgcaaaaac agagcaaaaa tacaggcatg
     2881 catcctcttc agacagagat tctatttggt cagattgctg gagcaaaagg tatcacaggt
     2941 ctggaattac cgttgagtaa tggtggaaaa ctccatgttc gagggaaaat cgatcgaatc
     3001 gatgtagctt ctgaacaaga agatacttgg ctaagcgtcg ttgattacaa atctagcgga
     3061 cgttcattcg atgtcacaga agcttattat ggcatggcta tgcaattatt gacgtatctg
     3121 gacgtagcat tgatggatgc ggtacgtttg actggaaagg cggctgttaa accagcagga
     3181 tcatattatt tacatgttca taatcctgta ttgacggaga cagatgatgt agagaagaat
     3241 acattgaaaa aatttagtta tgatggcgtt tttgtcgatg atcccgctct tttagaagta
     3301 ctagatcatt cactggaagc aaaagaacaa tcactgatct atccagtgaa aaaaaatgcg
     3361 aaagatgaat accaaaaagg tagtttcagt aaagacaaat ttttcacgga agaagaactg
     3421 caactattca tggcgcataa tcgggaaaat atgcggttag ctggagatgc gattacttcc
     3481 ggagaaatca aactaaatcc agcttataaa gataaacagc ggattgcctg cgaattttgt
     3541 ccattcagaa gcatctgtac gtttgatgtg atgctgaaag aaaataatta ccaccgtctg
     3601 gagaaaatag ataaggaaga agcactgcgt agaatattga aaaggagtga agaagagtga
     3661 atcaaattcc tttaaaaccg caaaatgaac gattcacaga tgatcagtgg caagcgattt
     3721 ttgatcaagg agataatcta ttagtctctg cgtctgccgg atcaggtaaa actacagtgc
     3781 ttgttcgaag agtgattgaa aaactaaaaa tgggttttga tatcgatgaa ttattgattg
     3841 tgacatttac tgaagctgcc gcaagagaaa tgaaagaaag aattcaagag gcattacaag
     3901 aatccgtcaa tagcgaaagt gaccctgtac gtagacagca ttttactaag cagttagttt
     3961 tattgcccac agcgaatatc tcaaccttac atgctttttg cctgacagtt attcgacgtt
     4021 attattactt aattgatatt gatccagtct ttcgcatgtt aacagatgaa acagaaacga
     4081 tcttgatgaa ggaggatgtg tgggacgagc tgagagaagc actttatgca gaaaatgatg
     4141 aacgattttt ccaattaaca atgaattttt ctaatgatcg ttcagatgac ggcttgacga
     4201 atctggtgtt ttctctttat gagtttgccc gtgccaaccc tgacccccaa aaatggctag
     4261 aacagttaag cgataattat cgtttgcctg aggggctagc gaaatctcga ttatatcaaa
     4321 aacaaatccg tcctttagtt ttggcagata tataccaatg tgtacagtta tatgaacaga
     4381 tgactcagtt agcacaaggt gaaggattag aaaaaatgca tgagcaagta gctggagaac
     4441 aacagcagat caagaatatc tatgaagcgt tctcgcaaga tcggttagaa gaagcttatg
     4501 ctggtttgga acaactaact ttttcaactt ttaagagcag tcggaaagca gaattgaaag
     4561 aaatttccaa tgaagtcaag ggcatgaggg ataaagcaaa aaaactgatt cagcagataa
     4621 gtaaaagtta ttttcctgtt tccccaagcc aaatggaaga attaacggac aaagcactac
     4681 cgttagtcga agaaatgaca aaagtcacgc aaagcttcat ggacggtttc agtatgcgta
     4741 aacgggaaaa aggtgtgctg gatttcaatg atctggaaca tttagcgttg cagattctca
     4801 cagaaaaaac gaaagatgta tggctgccaa gtgaagcttc aaaacattat cgaaaaaaat
     4861 tcaaagaagt aatggtagat gaatatcaag acgtgaacca attacaagaa gccattttat
     4921 actggctaag agaacccgat gatacaaaag gaaatatgtt catggttggg gatgtcaaac
     4981 aatccatcta ttctttccgt ttagcagatc ctagtttatt tatcgggaaa tacgagaatt
     5041 tctcaaagaa agaaggcgga cgtcgaatcg ttttggctga gaacttccgc tctagaaaag
     5101 aagtcctttc ttttacgaat cttatttttg aacaactaat ggatccagca gtgggtcaaa
     5161 tcaattatga cgaagcagcc aaactgatcc aaggattttc agactttcca gagaatgaac
     5221 agtttgagcc ggaaatcatg atctatgaaa aagaacagga agaatcagag attgagattc
     5281 cgacggatga tatactggaa gacaaaacag aaggcgaact ttttatgaca ggactaaaaa
     5341 ttcgtcaatt aattgattcc tcctttatga tttatgataa aaaatcaaaa aaaagtcgtc
     5401 cgatagagta caaagacatt gttctcttga cacctacaaa gaagaacaac ttaacgattt
     5461 tagagatttt caaaacattg gatattccat tagagatgaa tgatgctcaa aactattttc
     5521 aagcgacaga aattcgcacg atgatctcgc tgctacaatt aatcgataat ccctatcaag
     5581 atattccgct tgcggctgta ttgcgctcac cgatcgtggg tctgattgaa ccagaattag
     5641 ccagcattcg attagcgaac cgtgcacata cttactatga tgctgtgctt gcttatcaag
     5701 catcaaacga agatgaatta gcagctaagc tggaacattt tggcaagcaa ctagagcatt
     5761 ggcgagaact tgctcgccgt tcttcgatca ctgacttgtt atgggatatc tattatgaga
     5821 cgggatatct agagtatgtg gtcggtctgc cagcaggggc acagagacaa gccaatcttt
     5881 atgcattggt tgatcgtgcc aaagcttacg agcaaagttc tttcagagga ttataccagt
     5941 tcgtgcgttt cattgaaaaa atgcaagaaa aagataaaga cttagcagaa ccagtcattt
     6001 caatagaaga taatgctgtt cgcgttatga cgatccatgc aagtaaaggc ttggaattcc
     6061 cagttgtatt tttgttagat atgacaaagg agttcaactt acaagacttg cgcaatcggt
     6121 atgcttttga agaaaaactt ggagcaggaa ttcgctatat ggatcctgaa acacgagtgt
     6181 tatatgatac gttaccgttt caagccatca aattggcaaa gcaaaacaaa ttgttgtcgg
     6241 aagaaatgcg taaattgtat gtaggattga ctcgggcaga acaaaagctt ttcattgtcg
     6301 gttcctataa aaataaagag caaatgatcc aaacgtggtc tgaagcagct gatcatgagg
     6361 agttagtttt tgatcctgcg ctacgtttga agggcagaag cagcttgatg aattggattg
     6421 gttacggatt gatccgtcat cctgaaatgc agaaatactt agaggaagaa atttcgactt
     6481 ctcttcttca acattcaaat gcacagtttt ctatttcatg gatgaatcag caatcgatca
     6541 ttgaacaaag acagttgctt gctgaaaaag aactggttaa cttagatcag cagatgaaag
     6601 aagatgaaac tttattagca gattcgttac aaaaacgtct ggcatatgaa tatccttatc
     6661 aagcttcttc acaaaccaca agttatcaat ctgtatctga aatcaaacga ttattcgaag
     6721 atccagatga tacacaagaa tcacgtttga ctctggaaag cagtcagaac aaagcagcat
     6781 cccgtcaatt tcgttatacg caagaacaac tagcagaacc aaaatttttg caaaaagatc
     6841 ggcaagtgtc agcagctgct gttggaactg ctacgcatgc tttgttacaa ttactgccat
     6901 tagagatgcc aactacagag agtatccatc aaaaattaca ggaattggta aggaaacggt
     6961 tagtagacga aaaagtcgcg aaaaaagtag atgtttcttc tattatatgg ttctttcaaa
     7021 cagaacttgg tcaacagctg attgccaaca aagaaaacgt aaaacgagaa caaccttttt
     7081 ccatgctgct tcctgctgac gaagtatttc aagactatcc aaatcaagaa gatgaactat
     7141 taatccacgg aatcgtcgat ggatacctag aagaaaaaga tcatctcaat atctatgatt
     7201 ttaaaacaga ttttatttta catccggatg atccagcaga aatagatgca atcgtccaaa
     7261 aatatcaagg acagctaaga ctttaccaac aagcaatgtc agaagctttg aataagccag
     7321 tagaaaatgt tttcctaatt ttgcttcgag tgaaacaaat tataaacatt aacaaataat
     7381 tataattgag caaacttgac ttatgttttg taaggattat gctatactct gggaagaggt
     7441 gagtatgatg gagctaacac agacagaatt cgttttatgc cctaaatttg aaaaaacatt
     7501 ctctatttta ggaaaaaaat ggaacggatt gattatcgat gtactactcg aaaacggtcc
     7561 gcaacgcttt gttgagcttg cggcaaaaat cccgatggtc agtgatcgag tattagtcga
     7621 acgcttgaag gaattagaaa aagaaggaat agtcactcga aactttgcct gtagcgaaaa
     7681 gagccgttca gaatatctct tgactgaaaa aggagcagac ttgcaaaaag cgatgcgtca
     7741 aatacaagtt tggagcgaaa aatggatcac agaggaagaa tgcggttgat tttgtaaaaa
     7801 aaatcttgta aactatagtc catacgaata agtaaagaac gatgacgaaa aagagtagtt
     7861 tggctaaacc agttcaggga gatctgtcgc agactgaaag cagatcctgt gtttgaaaaa
     7921 tgaagttcac tttccgagtt cgtctgataa aatcagaccg gcaattgtcg ttaacgaagt
     7981 aagagtgcgg tgtaagtcat ttatccgcaa attaggatgg taacgcgaag acctcgttcc
     8041 ttaacaggaa tgaggtcttt ttgttttgta tttggaattt aaaggaggaa caagcacatg
     8101 tctctacaag cacaattaga gagcttgaaa gaagcaacgc tcgtcaaaat cacagcggca
     8161 caagatttaa atgaattaaa tcaaatacgt gttgaaacgt taggaaaaaa aggaccgatc
     8221 acagaagtat tacgtgggat gaaagatcta agtccagaag agcgaccaaa agtcggaagt
     8281 ttcgcaaatg agatccgaga tcttttgaca gaagagatcg agcgaaaaaa acaagtatta
     8341 gaagaagaag cgttaaatgc agctttggca aaagaaacaa tagacgtgac actacctggt
     8401 agaaaagtaa aacatggtac acgtcatatc gtgacacaaa tcatggaaga aattgaagat
     8461 atttttgtgg gtatgggcta tcagatcgta gaaggatatg aagtagaatc tgatcattac
     8521 aatttcgaac ggatgaatct gccaaaagat catccagcaa gggacatgca agatactttc
     8581 tatatttcag acgagatatt gattcggaca catacttcac cagtccaagc acggacaatg
     8641 gaaaaacatg atttctctaa gggtgctcta cgaatgatct cgccagggaa agtcttccgc
     8701 agagatacag atgatgcgac ccacagtcat cagttccatc aaattgaagg gctagttgtt
     8761 gataaaaaca tcacaatggg cgaccttaaa ggaacattag aagtcgtaat gaaaaaaatg
     8821 tttggggaag atcgtgaaat tcgtttgcgt ccaagttatt tcccatttac ggaaccatca
     8881 gtagaagtag atgtcagctg tttcaaatgt ggtggtgccg gttgtaacgt atgtaaatac
     8941 actggatgga tcgaaatttt aggagctggc atggtacacc cgaatgtgtt gaagatgtca
     9001 ggaatcgatc cagaagaata ttcaggcttt gctttcggcc ttggaccaga ccgcgtagct
     9061 atgttgcggt atggagtgaa tgatatccgt aatttctatc aaaatgactt acgtttctta
     9121 agtcagttca agggggagta agaaaatgtt agtttcatat aaatggctca atcgttatgt
     9181 agatttatcg aatgtaacac caaaagaatt agcggataag atgtctgtga caggaatcga
     9241 agtagaggga gtaacggttc cagaagaagg cttgaaaaaa atcgttgtcg gtgaagtcaa
     9301 ggaatgcgta ccacatccag attctgatca cctttctatt tgtcaagtcg atattggcga
     9361 agacgaactg tctcaaatcg tttgtggagc gcctaatgtg aaggttggaa tcaaagtgat
     9421 tgttgcactt cctaactcac gtatcgctgg taatgtaaaa atcaaaaaag gaaaaatgcg
     9481 tggccaagta tcaaatggca tgatttgctc attacaagaa attggctatt cagatagtgt
     9541 tataccgaaa gaatacgctg aaggtatcta ttatatgcca caagaagctg taaatggcga
     9601 tccagttttt ccttatttgg atatggatga ttcgattatt gaattatcta tcacaccgaa
     9661 tcgtgcggat gcattgtcaa tgcgtggcgt agcttatgaa gttggggcaa tttatcgtca
     9721 gactcctaca ttcgatgacg aaaagctggt agaatcctca cgtcctgcta gcgataaaat
     9781 tcaagtggaa gttgaagata aagaagcagt tcctgcttat caaatcagaa tcattgaagg
     9841 agtaagaatc cagccaagtc ctcaatggct gcaaaatctt ttgatgaacg aaggcattcg
     9901 tccaatcaac aatgtagtag atgtgacgaa ctatattttg cttttattcg gacaaccact
     9961 acatgcattt gactacgaca aattgaaatc aaaagagatc tttgtccgcc gtgcaaaaga
    10021 aaatgaaaca ttagtaacac tagatggaga atctcgggaa ttgacaactg acaatctcgt
    10081 cattactaac ggcaaagaac cagttgcttt agctggtgtc atgggagggt tagactcaga
    10141 gatcacgaat gaaacaacaa cagttgcact agaatctgct ttatttgatc caatttcgat
    10201 tcgtcgtaca gcaaaacaat ttaatttgcg tagtgaatcc tctgcacgtt ttgaaaaagg
    10261 aatcaaccat gcgactgttg gagaagccag tgaggttgct gcagcaatga tcgtttctct
    10321 tgcgggtggg gaagttctac aaggcgcggt caaaggctca gagatcaaag cagaagacgt
    10381 atcagtgaag atttcacttg aacgcatcaa tcaatattta ggaacatctc ttgtcgttaa
    10441 agaagtaaat gagatttttg aagcacttgg atttagctat gaagaaaagg agtatgttta
    10501 ttccgtagta gtaccaccaa gacgctggga tatccaaatc gaagcagata ttatcgaaga
    10561 agttgctcgt atttatggat acgaccagtt gccatctaca cttccaagtg gagaaacggt
    10621 tgctggaagc ttgtcaaaag aacaagaaac tactcgtaaa attcgtacaa tctttgaagg
    10681 aagcggattg agcgaagcaa tcagttatgc attgacaaca gaagaaaaat caagacagtt
    10741 tgttataaat gaaagtaata ttacacgttt ggactggcca atgagcgaag aacgttctgt
    10801 attacgaatg aatttgatca gcggactatt agatgatatc agttataaca ctgcccgaaa
    10861 aaatacagag attgctttat atgaaattgg tcgggtgttc ttccaagaaa atgatccacg
    10921 tacacatctg ccgcaagaag taaaacatgc agcaatcgct atttctggta tttgggaaga
    10981 aaaagattgg cagacgaaag ctcaaaatgt agactttttc accatcaagg gtcttttaga
    11041 aaacttattt gaacaactag gcatcactga agatgtccat tatcaaacag tgacagaaat
    11101 gaaggaaatg catcctggaa gaactgctgc gatttacctt ggcgaaaaat ttattggttt
    11161 tgtcggtcaa gtgcatccaa cgattacaaa aagttatgat attccagaaa catatgttgc
    11221 tgagtttgat ttatctgcta tagtggaagc tgctcaaaaa gggatcgttt tcgaagcagt
    11281 gacaaaattc ccagcagtca gccgggacat cgctttgctt gtaaaagaaa ctgtgacaaa
    11341 tcaggaatta acagaagtta tccgttctgc tgccggaaga tttttaacag atatccaatt
    11401 atttgatgtc tatcaaggag aaaacattga aaaaggacat aaatccatgg cgtatagcct
    11461 gacattcgtc aacccagaag caacattgac agatgaagaa atcaataaag caatggaaaa
    11521 agtcgaaaaa gcgttggtag aaaacctaga ggcaagtatt cgctaagaag gaaaatatag
    11581 taagtaacga tcaagtagct tttgaagacc atacatttga aaaaaagatg tgacacaact
    11641 tcgtcacatc tctttttttg attttaaaaa aggaatagca cagagacgag ataaaaaaac
    11701 aggcctttac agcctgcttt tttagagtaa atgaattaat ggaagtaatt gattcccatt
    11761 gctgatttta cttcagaaag tgtttgtgca gctactttag cagcttcttc actaccttta
    11821 cgtaagattt ccataacagc tgaaggatct ttttccaatt cttctcggcg cgcacggatc
    11881 ggtgcaaatt cagcttccaa tacatcaatg aggtatcgtt tgatctttac atcaccaagt
    11941 ccgccgcggc ggtaatgagc tttcatttct tcaattgctt ctttatctgt tccgaataca
    12001 tccaagtagg tgaagaccat attcccttct acttgtccag gatcttgtac atggatgtgg
    12061 tttggatcag tatacatact catgactttt ttctgtaaga catcggcagg atcggagata
    12121 taaataccgt ttcctaacga tttactcatt ttgccatttc catcgattcc aggtaatcta
    12181 cccattcctt ttggtgggaa tacgcctttt ggttccacca agacttcacc atatgtatga
    12241 ttgaagcttt gtacgatttc ctgtgtctgc tctagcattg gtttttgatc ctcaccaaca
    12301 ggtacaagat tcgctttgaa tgcagtgata tctgctgctt gagaaacagg atagataaag
    12361 aatcctgtag gcacgctttc accgaatttt ttttgttcga tttctgtttt gacagtcgga
    12421 ttgcgccgaa cgcgtcctac gctgactaag ttcaaataat acatggttaa ttcagctaat
    12481 tccggaattt gtgattggat aaataaagta gattttgcag gatctaatcc cacggctaaa
    12541 tagtctaaag caacttgcaa gacatttgat gaaaccttct caggattttt agcattatct
    12601 gtcagtgctt gcatgtcagc aatcatgaca aacagttggt tgtcttcatc tgcctgcata
    12661 gccactcggg tttttagaga accgacgtaa tgccctaaat gcagcttccc agttggtcga
    12721 tctcccgtta aaataatatt tttcaaaaaa gacacctctt tacgatttgt aagtctgagc
    12781 acttaatatc ttaccgtttt tcctgaaaag aaacaacagt tcctaaggaa aaaacaagga
    12841 aagaggataa aataactaat agattagaaa tggaagaaat atttatggga gaataaacgt
    12901 tctaagaaac tttacaaatt actaaactat cagatataat gtattttatt atacatcttt
    12961 aaaagaaatc ttactaaata ataatgggag tgtaattcta tggcaatgat taaatttgat
    13021 cacgtggata aatattatgg caagttccac gcattaaaaa atatcaatct cgaattcgag
    13081 aaaggagaag ttgtcgttgt cattggtcct tctggttcag gaaagagcac gatgcttcgc
    13141 tgtatcaatg gattagagac gatctcttca ggtaagctgc tgattaatga tactgacttg
    13201 catgataaaa agacaaaact gacagaagtc cgaaaaaaca tcggcatggt tttccaacat
    13261 ttcaatttgt acccaaataa aactgttctg gaaaacatca aattagcacc aatcaaagtg
    13321 ttgaagcaag accaggcaac tgcagtcaaa aacgcggaga aatttttgaa aactgtcaat
    13381 atgttagata agaaagattc ttatccttcc atgttatccg ggggacaaca gcaacgggtg
    13441 gcaatcgcca gaggtttagc gatgaatcct gagatgctgc tgtttgatga acctacttct
    13501 gctttggatc cggaaatgat tggtgatgta ttagacgtta tgaaaaaatt ggctcatgac
    13561 ggtatgtcaa tgattgtcgt gacacatgaa atgggctttg ccaaagaagt ggcggatcgt
    13621 gttatcttca tggctgatgg agaagtattg gaagacagca gaaatgtgag agactttttc
    13681 gaaaatccaa atgaagtccg agcacagcaa tttatcagta aagttatcaa tcattgatag
    13741 gaggaaaaag atgcgcaggt taaaaaaaat acgcctgatt ttccttttag gcattgcttt
    13801 tcttgcacta gccggatgta aaggaaatgg gttggcaaat gaagatattt tagagcgaag
    13861 caaatctacc aatgaaatca tctggggtgt caagtatgat actcgattat ttggaatgat
    13921 ggatattgag agcagaactg tacaaggatt tgatgtagat attgcaaaag caatcactaa
    13981 aaagatcctt ggtgacaatg gaaaaacaga atttgttgaa gtcacttcta aaactcggat
    14041 tccattattg aaaaacggaa atatcgatgc aattattgca acgatgacga tcacagatga
    14101 acgaaaaaaa caggttgact tttcagatgt ctatttcgat gctggccaag ctttgttggt
    14161 aaagaaagga agccaaatca aaagtgtaga tgatttgaat gcttctacaa cggttctagc
    14221 agtcaaaggt tctacatcgg ctgcgaatat ccgacagcat gcaccagatg caaaaatttt
    14281 agaattagaa aactatgcag aagcatttac tgctttacaa tctggtcagg gagacgcgat
    14341 gactacggat aatgcgattt tgttagggat tgcagatgaa aatccagagt atgagttagt
    14401 tggtggaacg tttactaatg agccttacgg gattgcgatc aacaaagggc aagaaaactt
    14461 cttgaaagct gttaaccaag cgctagagga aatgcatgca gatggcacat acgataaaat
    14521 ctatcaaaaa tggtttccaa atgaaactga aggaaaagta gagtaagggg gagaggcaat
    14581 gagcgaattg atacaaactt atggaccaat ctttgtcgac gggttcaaga tcacattgtt
    14641 ttcgagtgtc ttagcacttg tgtttagttt gattatcgga acgttaatgg caatcttcca
    14701 attatcaaag aataaagtag tgagcacctt agcaaaggca tatgtagaat tttttagaaa
    14761 cattccatta ttaatcatcg tgatgttttt ttatgttgtc gtaccgattt attggtttaa
    14821 tctagatgga ttccaagcag gtacgattgg attaacgatc tatacatctg cttttattgc
    14881 tgaaacagta cgttcaggga ttcaaaccgt accaaaaggt caaacagaag caggactatc
    14941 ttctggtttt acctattcag aaatcatgcg ttatattgtt ttaccgcaag cattcaaaat
    15001 cgttatcccg ccattaggca accaatttat caacctcgta aaaaactcat ctattttagc
    15061 aatcgtagct ggtttagatt tgatgtatca aggagacttg atcgctagtg aaacattcaa
    15121 taccttcgat acgtatatca tcgttgggtt attttactta gttatcacgc taccgttatc
    15181 ttacttaatg gtttatcttg agaaaaaatg ggcggttcgt tcatagaagg aggggaaata
    15241 catggatttt agcggcgctt tttcatggat gaatatccgt tttttattgg aaggattaaa
    15301 ggttactgtt gaagtttcat tgttttcgat catttttagt ttcttgatcg gtggtctgac
    15361 aggtgtgatt cgttttgcga atatcccttt cttttccaaa atccttggtg tagtgattga
    15421 tattatacgg aatcttccat tattattgat cattttcttc acttactttg ccttacctca
    15481 aatcggcatt cagatgaaca tcttctggtc cgctgtcgca gcattaacga tttttgagtc
    15541 agctatgttg tcggaaattt tccgagctgg actcaatgct gttccaaaag gacagatgga
    15601 agcaggatta tcaacgggac tgacttatgt agaatcgatg cgaacgatcg tgttaccgca
    15661 agcatttaaa tcaatgatcc cggcaattgt gagccaattg atttcactga tcaaagatac
    15721 ttcattagca gtaatcattt ctttacctga actttctcat caggcacgta ttatttatgg
    15781 acagaacacc aattatgtgc ttccgatgtt catcatcatg acacttatgt acttcgtggt
    15841 atgttacgcg ctttctctgc tttccggtta cttggaaaag agacggtaca gttattaata
    15901 gatgattctt ttagcggttg tggcaaacta aa
//
LOCUS       DAZULR010000055        15860 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.056, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000055 DAZULR010000000
VERSION     DAZULR010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15860
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.056"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(12..482)
                     /locus_tag="ACG8ZV_002214"
     CDS             complement(12..482)
                     /locus_tag="ACG8ZV_002214"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HFS4997499.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(641..1099)
                     /locus_tag="ACG8ZV_002215"
     CDS             complement(641..1099)
                     /locus_tag="ACG8ZV_002215"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0043768 - S-ribosylhomocysteine lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HFS4997500.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            complement(1270..2415)
                     /locus_tag="ACG8ZV_002216"
     CDS             complement(1270..2415)
                     /locus_tag="ACG8ZV_002216"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HFS4997501.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            complement(2428..3345)
                     /locus_tag="ACG8ZV_002217"
     CDS             complement(2428..3345)
                     /locus_tag="ACG8ZV_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent cysteine synthase family protein"
                     /protein_id="HFS4997502.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            3773..4336
                     /gene="efp"
                     /locus_tag="ACG8ZV_002218"
     CDS             3773..4336
                     /gene="efp"
                     /locus_tag="ACG8ZV_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HFS4997503.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            4437..4607
                     /locus_tag="ACG8ZV_002219"
     CDS             4437..4607
                     /locus_tag="ACG8ZV_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997504.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            4822..6081
                     /gene="lysA"
                     /locus_tag="ACG8ZV_002220"
     CDS             4822..6081
                     /gene="lysA"
                     /locus_tag="ACG8ZV_002220"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HFS4997505.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            6068..6868
                     /gene="dapF"
                     /locus_tag="ACG8ZV_002221"
     CDS             6068..6868
                     /gene="dapF"
                     /locus_tag="ACG8ZV_002221"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HFS4997506.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            6871..7752
                     /gene="dapA"
                     /locus_tag="ACG8ZV_002222"
     CDS             6871..7752
                     /gene="dapA"
                     /locus_tag="ACG8ZV_002222"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HFS4997507.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            7749..8465
                     /gene="dapB"
                     /locus_tag="ACG8ZV_002223"
     CDS             7749..8465
                     /gene="dapB"
                     /locus_tag="ACG8ZV_002223"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HFS4997508.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            8471..9166
                     /gene="dapD"
                     /locus_tag="ACG8ZV_002224"
     CDS             8471..9166
                     /gene="dapD"
                     /locus_tag="ACG8ZV_002224"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HFS4997509.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            9182..10183
                     /locus_tag="ACG8ZV_002225"
     CDS             9182..10183
                     /locus_tag="ACG8ZV_002225"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HFS4997510.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            10180..11541
                     /locus_tag="ACG8ZV_002226"
     CDS             10180..11541
                     /locus_tag="ACG8ZV_002226"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HFS4997511.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            11501..12652
                     /locus_tag="ACG8ZV_002227"
     CDS             11501..12652
                     /locus_tag="ACG8ZV_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFS4997512.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            12627..13796
                     /locus_tag="ACG8ZV_002228"
     CDS             12627..13796
                     /locus_tag="ACG8ZV_002228"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFS4997513.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            13971..15350
                     /locus_tag="ACG8ZV_002229"
     CDS             13971..15350
                     /locus_tag="ACG8ZV_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFS4997514.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            15631..15860
                     /locus_tag="ACG8ZV_002230"
                     /pseudo
     CDS             15631..15860
                     /locus_tag="ACG8ZV_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5185 a         2799 c         3378 g         4498 t
ORIGIN      
        1 tttttattaa gttaaagaac ggattcaatt gcagcggtca ttttcaatgg agaagtttgt
       61 ggtgcaaatc gttcgattac tttgccattt ctatcaatca aaaatttagt aaaattccat
      121 tttattgctt tagtgacagt accaggagct tcatttttaa gataagtaaa aagaggatct
      181 gtattttctc catttacgtc aatcaattga tgcataggga aggtaacgcc ataagtggtt
      241 ttacaagctt ctgctgcttc agtcgctgaa tctagctctt gtttaaattg attggaagga
      301 aagcctaaga taaccagacc ttgtgtctga taagcttggt aaagttcttc taattgttta
      361 aattgaggtg ctagaccgca ttttgttgca gtgttaacaa tgattatcgg tttgcctgca
      421 tattttttca atgaatagac agtgccgtct tctaaagtag tttcaaaatt ataaatagac
      481 ataaagtttt ctcctttcta ttttatataa taaaaagagc gctaaactga aaactagcta
      541 tttgttttcc cgtttagaac tcttttcaga caataaatat ttaataaaat acgaagataa
      601 gatagctata ttgcttctca tctttacgtt cttttagaaa ctatgcttct acttcagacc
      661 attcatcgcg ttttgctaaa aattcacgag ccaaagcttg tgcaccttct agtgtatggc
      721 tggcagccca gccacattgt gtttcattgc ttgcaggtac ttcagtagct tcaagaacat
      781 ctttcattgt tgcttcaaga acatctaaaa tgtcttcgta gctttcatga ttcaatacag
      841 tcaagtaaaa gcctgtttgg catcccattg gagaccagtc tacgatgtaa tctgcgtgat
      901 tgcggattag ttcggcagtc aagtgctcaa gtgaatgtag acttggcatg tccatgtgtt
      961 ctttatttgg ttgtttaaag cggacgtcgt atttaatgat gacatcgcca tgcgcacccg
     1021 tttttcgatc agctacacgt acataaggtg ctttgacttt tgtatggtca agattaaaac
     1081 tttcgacatt cattctcatt tgtaagactc ctatctgttt gttcattcgt tttgatgctt
     1141 ttcactaaag aattatttag tgaaatttac aaaaacgtct ttctacttga ttctaacact
     1201 tatcgtttcc aaggtgtagc aatctgaaat attttttaga tttttctgct aagtcgttta
     1261 ttgggacttc tagttcttga ttctgtcaaa tgcctgagct aaatcgttta tgagatcctg
     1321 accatactca attcctacag aaagacggat caagccgtcc tttatgccag cctcttctcg
     1381 tttttctttt ggaatagacg catgagtcat gacagaagga atttccacta aactttctac
     1441 gccacctaaa ctttctgcta aagtaaatag ttggagtgat tcaacaaatg gaatagcaga
     1501 ttcttcattt tttaaagtaa aagaaatcat tccgctaaag ccgctcatct gctgcttagc
     1561 aactccatgg agttcatgat cgggtaatcc tggatagtag accttttcta ctgctggatg
     1621 agaaaataga aaatcagcta ccacaaaagc atttttttga tgttcctcca tacgaacact
     1681 tagtgtcttg attccgcgct gaagtaacca gctatcttgg ggaccaagta cggctccgat
     1741 agcattttgg taaaatccga tctgatcggc tagatcttta tggttagaag tcactaaacc
     1801 agctactaca tcgctgtgtc cgcctagata tttggtaccg ctatggacaa cgatatcaga
     1861 accgagatct aaaggtcttt gaaaataagg agtagcaaat gtattgtcag caataactat
     1921 caatccatgt tgatgagcca gagtggcact tttttctaaa tcagtaatct ttagaagcgg
     1981 attgctaggt gtttcaagat aaagtgcttt tgtattgggt ttgatggatt gttctatttt
     2041 atcaagatta ctcgtatcta tgatcgtgta ctcgagacca tttttagtaa gaactttgtc
     2101 aaatagacgg aatgttcctc catagacatc atctcctaat aagatatgat cgccagcttg
     2161 aaaaagagaa aaaacggcat gaatcccaga aagaccagaa gaaaaagcga atcctcgaac
     2221 accgccttcc aaatcagcaa tcagttcttc caatgcaaaa cgagtaggat taccagatct
     2281 tgaatattca tattgtttag gctggccgac gccatcttgc cgataagtgg atgtttgata
     2341 aataggtaca ctgacagctc ctgttgtggg atcttcactg atgcctccgt ggatcaattt
     2401 tgtttgaatg tgcatgtttc tttcctccta taagtaaatg ttttttgata aatagcggtc
     2461 tgctgcgtct ggaaaaatcg taacgacacg atgaccaggt ggtaaacgac gaatttctct
     2521 taatgctgct gcaaaagccg caccactcga acttccaact aatagtcctt gttctcgtgc
     2581 taactgccta gtatagttaa acccttctac atcagagatt gtctcgatct gattgattga
     2641 aaggggagaa agaaacggcg gaatgaattc tacaccgata ccctcaattt cgtgaggggc
     2701 tggatcacca ccatttaaca cagagccctc tggttctaca ccgattattc gaatgtcggg
     2761 atatttttct ttcaaaaagg tagaagttcc agcaaaggtt ccaccactcc caattcctgc
     2821 tacaaaacta tggatatttt ctttgatttc atgaaagatt tctggcccta acgtatgata
     2881 gtaagcagca ggattatctt tattttcaaa ttgaagaggc agatagctgt ttgatatctc
     2941 ctctgcaagt tttttacttt tgctgatggc accgatgatt ccttgctcac taggagaatg
     3001 gatgatcttt gctcccaatg ctttcatcaa ttgttgtttt tctaagctaa acttctctgg
     3061 aacaacaaaa accgttctta atttgtatgt gagtgcggcc agagcgatcc caattcctgt
     3121 atttccggca gttggttcga tgatcgtcgt tttttcattg atttttcctt gggcaaatcc
     3181 ttctttgatc aaataactgc ccaatctatc tttgatactt cctccaggat ttaaatattc
     3241 tagttttgca taaatagcag aacctttagg catagaatag tgctgattgt caaagcgata
     3301 aagcggtgtg gaaccaatag cttctgtaat tgtcgagata atcatgtggg cctcctaaaa
     3361 aaagataata aaaaaaggag ctgactatta aatcagctcc ttgaaagaca tagagaaaaa
     3421 ttgagtagat aaaaagataa gttacctggt actcattcta tgaagggcaa ttaatagaca
     3481 tgacaaatag tatgctgctt ttatgcacca tacaacagca acgattcaat tgtttttggt
     3541 tgctgactgt catgtgtatc cctccaagta aaatttttat taacgatagc atgaaaaaaa
     3601 ataaaagtca aaggcttgaa agaaaaaaat atttcgatag catcgtttac ccgtgtttat
     3661 ttttctgaca aataggcatg agaccttaaa agatagagaa tactctagtt ttctggccgg
     3721 ttgtctgata caataaagtt gattatgata aagaaaagaa ggagcaaaaa taatgatctc
     3781 agcaagtgat ttaagagccg gtatgacttt cgtacaagac ggcaaactga ttaaagttct
     3841 ggatgcaagc caccataaac ctggtaaagg aaatacagtt atgcgtatga aactgaaaga
     3901 tgtccgttca ggtgcaacat acgacacaac gttcagacca gaagaaaaat ttgaaaaagc
     3961 acatatcgac acaaaacctg tacaatattt gtacacgatg gatgatacag ctttcttcat
     4021 ggatttggaa acatatgagc aatatgaaat tcctgtagaa acagtagaag aagaaatgaa
     4081 atatatccta gaaaacatgg aagtaaaaat ccaatttttc ggtagcgaag tcatcggcgt
     4141 tcaattacca acaactgtcg tattacgtgt tgtggaaaca caaccttcca tcaaaggtgc
     4201 aacagtcact ggttcaggta agccagcgac aatggaaact ggcttagtag tcaatgttcc
     4261 tgacttcatc gaaacagatg aattgttgga aatcaataca gcagaaggtt cttatgtaaa
     4321 acgtgcgtca aaataattcg ctaacggatt gataagaatt tgaaaacaga gcttgacctc
     4381 ttgaaaggca gatcatcgga tctgcctttc aagaggtttt ttgtggaatc agcaaattga
     4441 aaaataaaaa agtatttgat tttatttata ttttgaaaga tgaatggcaa aagctagaga
     4501 aagaaaaaac tgcacttatt tatgaagaaa ttgaaatgat tcataaaatt gaaaatatcc
     4561 gaactattcc gaactatatt gaagcgaaaa tattttttca tcactaaata gtgttgaatt
     4621 tatgttttta tgtataaata gcttctaata gttcgggtat tttgttttta taaccatttt
     4681 tattcttatt tttaaaaaaa tatttcgaaa tatactagac aattcagaaa attttgttta
     4741 atattattcc aataaaattc aaatctttat caaatgaaat tccaataaaa acggaaaaaa
     4801 agtgaaaaga ggaatgaaaa aatgacagaa ttgataattg gcggagtcac agcaagcaca
     4861 ttggcagaaa agtataagac acctctgtat gtgtatgatg aagaaaagat gagacaaacg
     4921 atgctgtcat tcaagcgagg ctttgtatcg aaacgttttg atacaaaagt gctttacgcc
     4981 tctaaagcat tccaaacgat tgagatgctg catttagttc gtgaatatgg attcgggcta
     5041 gatgttgtca gtggtgggga aatctatacc gctttgcaag ctgattttcc tagagatact
     5101 atctacttcc atggtaacaa caagacgcca gaggaactga tctatgcact tgaaaatgat
     5161 ttgttgcata ttgttgccga taatttgatg gaagttgaat tattagcaga attaagccaa
     5221 cgctatttaa aaaaaatctg tatcatgctt cggttgaatg tcggagtaga agcacatact
     5281 catgaatata tcgtcactgc gcatattgat tcaaaattcg gcatgagcta tgaaagtaaa
     5341 gagtgccaac aagcccttca gttgataaaa gaaagcagct atctagagtt agaaggattt
     5401 catgctcata tcgggtcaca aatttttgat gttactgctt ggttagctga aatcgacaaa
     5461 ttgacgaatt acttaaccga ttttgaccaa cctctttcct tgaatcttgg cggagggttt
     5521 gggattcgtt atacacaaaa tgatcagccg atcccagtcg aagaggcact aaaaaaactg
     5581 attgaatata cggaagaagc tttggaaaaa cgaaaactga ccattcgtca attactgatc
     5641 gaaccgggta gaagtattgt tggagaagct ggtacaacac tatacacgat tggtttcatc
     5701 aaaaagacac cacataaaaa atattacttt gtagatggcg ggatgacaga taatatccgt
     5761 ccagctctgt atcaggcaga atacgattgt gatttagcag caaaactgtc ggaagaaaaa
     5821 acagagaaag tgacgattgc aggaaaaatg tgtgaatcag gcgatgtggt aattaaagaa
     5881 gcttatttgc cgaaagcaga atcgggtgat cttttagctg tttattccac gggagcttat
     5941 ggatactcga tgagcagcaa ctacaatcga gcgacacgac cagcagttgt ttttgtcaat
     6001 aatggccaat caagactgat tgttcgcaga caagcatttt ctgatctact aaggggggaa
     6061 gtttcctatg atccttcata aatataatgg ctgcggaaat gattttatct tattagatta
     6121 cgcagaagac acagattata gtcaattagc cgcttcttta tgcacaaaag aaaaatatga
     6181 tatagacgga ttgatcgccg taaaaatcga tccgttggaa atgatctatt acaacaaaga
     6241 tggcagccgc gcgccgatgt gcggaaatgg cattcgctgt tttgctcgat acgtaaatga
     6301 tcagaacatg atgaatgaac aggaattcaa cgtagagaca ttagcaggca caagaaaaat
     6361 tacggtgttg gatccctcac ctttttattg cagcgtagat atgggagtgc cagatgattc
     6421 tccggaaaaa atcaaagcta atcaaactta tccaataaaa aaccaggaaa tagagatcaa
     6481 tggtgaaaaa gtaacgatca ctagtttatt tttaggaacg attcataccg ttgtttttgt
     6541 tgaaaatgcg cgtgaggaag tctggagaaa aagaggtgaa ctgatctgtc atcatccttt
     6601 gttcaaagaa aaaaccaatg tcaactttgt agaagtagtc aatgaacaag aattgatcgt
     6661 ccgtacctat gaaagaggag taggttggac acttgcttgc ggtacaggtt gctgtgcctc
     6721 ttatgtggtt gctaaggaaa ctgggaaaat ttcagcagat caggtagttg ttcacttgga
     6781 acaaggagac ttgatgatct ctggtgagga tgcgatacaa atggctggcc cagcagttca
     6841 tgaatggaca agaatattgg aggaatgaag atgataaaag gttcgatcgt ggcgctgatc
     6901 acgccgatga atgaagaggg atcagtagat tatgctggtt tggaaaaatt gatccaattc
     6961 catttagatg aacaaacaga tggattatta gttttaggta caacaggaga atcttctacg
     7021 ctcacacaat ctgaggagga gcagatcctt caactgacag taaagaaagt ggctggccgt
     7081 gtgccggtga ttgcaggagc tggaacgaat aatacgaaag aaacgattga aaaagcgaag
     7141 cattttgctt ctttgggggc agacgcactt ttggtcatca ccccttacta caacaaaaca
     7201 agtgatgcag gactagctgc tcattttaca gcaattgcag aagcctcacc gattccgctt
     7261 attttgtata atgttccttc tagaacaggc atgtcgattc caatccatgt attagtaaat
     7321 ttagcagaac atcctaatat cattggtttg aaagaagcct caggagatat ggcttatgtg
     7381 atggatgccg ctcggttgat tggagaagaa ttcttccttt acagtggaaa tgatgatttg
     7441 atcctaccag taatgagtgt aggaggaagc ggtgtaataa gtgtatgggc gaatatccaa
     7501 cctaaaatag tccatgaatt agtaaaagat acgcaggacg gaagatggca gcaagcaaaa
     7561 gaaaagcaat taaatgcact tgaactgatc catgccttgt tcagtgagac caatcctatt
     7621 cctgtcaaag cagccatgtc attattagac ttaccttccg gacctctacg cctgccttta
     7681 gtttctcttt caaaagagaa aaagaaacaa ttagctcagc ttttgttaaa agaaaggacg
     7741 gttgaaaaat gaaaatcgga ctgattggca gtggacagat gggaaataga gtcgaagaag
     7801 ttgcacaaga aagaggagat acggtccttc ttttacggac ggcacctaaa gaagcaacta
     7861 cgcttgcttt tacggaactg ccagaactgc ttattgattt ttctcatcca gataatttag
     7921 agaaaatcct ttcgtatagc ttatcatatc aacttccgtt agtcattggc acgacaggtt
     7981 atacacaatc acagttccaa gaaataaaag aacatgccaa acatgtacct gtgatgtata
     8041 gtgctaattt ttcgttcggc atcatggtga tgaatcaact aatcaagcaa gcagctgcaa
     8101 tgttgcaagg ctggcagatc gaactgattg aaaaacatca tagtcgtaaa aaagatgcac
     8161 catctggtac tgcaaatatg ctgcttcaaa caatccaaga agtgcaaaag ctgcagcccg
     8221 tatacaactg gcaagggaaa aaaagagaag aaaaccaaat tggtgtacac agtattcgtg
     8281 caggttcttt acctggtgaa catgatgtat tgtttgctgc tactgatgaa atatttacga
     8341 tcaaacatga atctttttct aatcgaatct ttgctgcagg cgcagtagaa gcagcggact
     8401 ggttgaaaga tcagtcacca ggttattaca aattagaaga tttattaatg gacaaagggg
     8461 tgtaaaaaac gtggaagctc aagaaatcat ccgctacatt caaacggcat ctaaaaagac
     8521 gcctgtgaaa gtctatctga atgtaaccga gccaatcgaa tttaaagaaa gtaaagtttt
     8581 tggtgaagga agcagcttcg ttgtttttgg tgactatgag acgattgctc cggttttaga
     8641 agctgaatca gaaaaaatca ttgaaatcga aatcgaaact gctgcaagat acagcgcagt
     8701 tcctttgcta gatattaaaa aaattaatgc tcgtatcgaa ccaggtgcta ttatcagaga
     8761 tcaagtgtca atcggcaaca atgccgtgat catgatggga gcgattatca atattggtgc
     8821 agtaatcggt gaaaacacga tgattgatat gggtgctgtc ttaggtggac gagcgacagt
     8881 gggcaaaaac tgccatattg gtgcaggagc tgtcttagca ggtgtgatcg aaccagcatc
     8941 ggccaaaccg gttatcgtag aagacggcgt actggtaggt gcgaatgcag tgattgttga
     9001 aggtgtccat atcggaaaag atgcagtcgt ggcagcagga gcagtggttt tagaagatgt
     9061 ggcagcagaa actgttgtcg gtggaatacc tgcacgtgta ttaaaaataa gtgatgatca
     9121 gacaaaagaa aatacagcat tgattgctgc gttacgcgaa ttatagagga gatggagaaa
     9181 aatgcgcgaa atagatacct gtattgtggg ggcaaccgga ttagtcggcc aaacgatgct
     9241 caaagtgtta gaagaatatg attttccagt aggacgattg aaattattag cttcaaaacg
     9301 ttcagccggt aaagtttgtg tattcaagaa aaagaaacac actgtacagg aattgacaga
     9361 aacttcattt gaaggatatg atttagcgct attttctgca ggtgcttctg tatccaaaga
     9421 gtttgcgcca atcgcacgaa gtcagggact atttgtcata gataattcct cagcatggcg
     9481 ggaagattcg gatattccat taatcgttcc agaggtcaat ctggaagact atacattgaa
     9541 tcggctgatt gcaaatccaa attgttcaac cattcaagcg gtacttccgc ttaaagcttt
     9601 acaagaagcc tttggtatcc agcgagtcaa ttattcgacc tatcaagcag tttctggttc
     9661 cgggcaaaaa ggcattgaag atcttcatcg tacgcaaaat gacgaggaac cagttttgta
     9721 tccttataat attagccaaa cggtgattcc ggaaatcgat cagcctttgg aaaatgggta
     9781 tacaaaagaa gaacagaaaa tgataaatga gacccgtaag attctgcatc agcctgcttt
     9841 gccagtatca gcaacctgcg tacgtgtgcc aatcgaaaat ggacatggag tctctgtggc
     9901 agttcaactg caaaaagagt ttacgacgga agaaattaga gagtgtctca gccagtttcc
     9961 agggattcaa ttagaagatg atctagcagc acataaatat ccgacgagca ttcttgctag
    10021 aggaacagat atggtttatg ttgggaggat cagaaaagac acttctttag agaacggatt
    10081 gttgttctat acgactgccg ataacatacg caaaggagcc gctgcgaatg ccgtacagat
    10141 tgctgcagct ttaatgcaga aaatagcgga ggtggcaaga tgagtaatac gctgaaagta
    10201 gcgaaattcg gcggaacatc gatgtctcat gaagagcaat tcaaaaaagt ccgtacaatt
    10261 gttctttcag atcccaatcg ccaagtgatc gttgtttctg ctttaggcaa acgtacgtca
    10321 gatgatgaca aagtaacaga cttactttat ttgatttatg cttaccttca gcatcatgtt
    10381 gattggacac ccctttggaa aaggatttgt gatcgtttca ttcaagtaag agatgttctt
    10441 gccctgcagt tacctattga agatgaacta gcacgcatac agaaacaact ggaagacgaa
    10501 aagataactg aagattattt agtaagtaga ggtgaatatc tgactgctca actgatggct
    10561 gagtatcttg gttaccagtt tattgacgca aaagacctga ttttctttga ctatgatggg
    10621 aaaatcgatc aggaaaaaac agcacaggaa atcacaaaag catttaaaag atatccgaaa
    10681 atggttgttc cagggtttta cggggcgaac cctgcaggaa aagaaaaatt attgggccgt
    10741 gggggaagcg acattaccgg cgcgatactg gcgaagatgt tgcaagcgga aagttatgag
    10801 aattggacgg atgtttcagg aatcatgatg gctgatccgc gaatcatcga tcatcctaaa
    10861 atcatcgagg aaatctcttt tagagaactg agagagatgg cttatatggg ggctaacgtt
    10921 cttcatgaag cagctgtttt cccagttcaa gaggctgata tccccatcca aataaaaaat
    10981 accaatgatc ctttcgctca agggacaaaa atatcgaatc acgaaataga aaaggaaaat
    11041 ggactgacag gaatagctgg acgcaaggat tttctttcca tcactttatt caaacgtcat
    11101 atgtccgatg aaatcgggtt tatctggaaa gcaatgagca tttttgctaa acatgagata
    11161 tcaatcgaac atattccttc agggatcgac aatatcggag tgatcgtctc agcagaagcg
    11221 attgccgata agttatttct catcacgaaa gaattaaaag aaacacttgg cgtggaagaa
    11281 atcgtcgtga tcgaagactt agctttgatc tctgtcgttg ggggtccgca taaagaattg
    11341 attggattat ctgggaaagt gttatcgata ttgaacaaat tagaaattcg cacatcgatc
    11401 ttatcacaag gagcacagga gttgaatctg atcatcggtg taccgaataa tcaatatgaa
    11461 acagtagtga agggtatcta tgaagggatg gtgaatacgg atgctgaaag aatatcgaat
    11521 ggcactccat caaattcctg aaatcgggtt tcatgaattc aagacaaaaa aatatttata
    11581 tgaacaagta aaaaacagcg aggccgttat ccatgaaatc ggcgaaacag gactactcct
    11641 ttattttgat aatcagcaag aagaaacgat tgcttttcga acagatatcg atgcactgcc
    11701 agtcaaagaa gaaacgaatc tctcttttgc ttctaagcat gaaggttata tgcatgcatg
    11761 tggtcatgac ggacatatgg cgatgctttt agggttgact gactttataa ctaaacacat
    11821 tgaggatctt atttataatg tagtactgat ctatcagcca tcagaagaaa tttccggtgg
    11881 cgcacaaagc gttattcagt caggattgtt ggataaatat gaagtacaag caatatttgg
    11941 ctttcatcta tggcctggac tagctaaggg agaagttttc tctcgaccag gacctttgat
    12001 ggcacaaagc agtgaaacag acattatcat taaaggccag tctgcacata ttgcttctag
    12061 tgaaaaagga atcgatagtc tggaggcagc tgtacgattt ttgaagaatg tttatgattt
    12121 tgaccggcaa ttaccggcag agtggaatca tctaatgaaa tttggccaaa tccaaggtgg
    12181 aacgatccga aatgttttag ctggagaagt tattgtatcc ggaagtatcc gttcttacag
    12241 ttcagatatg caaaattatt tgaagagggg attagaccat ttagcagaac agtttcactc
    12301 tacagctact atttcttttc gctataatga cggctatcca gctgtaatca accatagagg
    12361 cttatatgca gcactgttag attcaaacaa actacatgaa ttagatgctc cagttcttca
    12421 agccgaagat tttggcatat atacgcaaca atatccatgt gtatttttct ttttaggtgt
    12481 cggtgatacc cctgctttac atgatccgac gttcgatttt gatatggatg ttttagaaaa
    12541 tggtgtagaa tggtacaaaa cgattctttt tacagaaaat cttcttgtaa aaatcgatag
    12601 cagttcaaaa gaggagcgag taaataatga tgaatttatc caatcgattt agtcctaggc
    12661 tttctagaat agaagtatca aaaatacgac aattcgatca gcaaatatcg tcgataccag
    12721 atgtgatcaa actcaccctg ggagaaccgg attttccaac tcctgaacat gtcaagcaag
    12781 caggaatagc agcgattgaa gaagactttt ctcactatac cggaatgaga ggattagagg
    12841 aactgcggga agcggcttgt atatttcagc aacagcgtta tggattaact tatgatccgc
    12901 aaacggaagt tttgacgaca gttggtgcaa cggaagcgat tgcctctgcg ttgttatctg
    12961 ttttggaaga aggagacaag gttcttattc cagcgcctgc ttattcagga tatcagccat
    13021 tagtggaact agctggtgct gaattgatcc cgatagatac ttctgacaca gggtttgtct
    13081 gtcagccgga acaatttgaa cgagcatttg aacaatatgg atcagctgtc aaagcagtca
    13141 ttttaaacta tcctaacaat cctactggga cgacattgtc tgcaaaacaa ttgaaagcaa
    13201 tcgctgaggt tttaaaaaaa tatccggtat ttgttataag tgatgaagta tatgctgaat
    13261 tgacttatag tggaacgcat atgtccatag ctacttatct tccagaacaa acaatcgtga
    13321 taagcgggtt atccaagtca catgcgatga ctggttggcg agtgggcttt atttttgctc
    13381 aaaaagccct tattgacgaa ctaattaaag tccatcaata tctggtgact gccgctacaa
    13441 cgatgtcgca aaaagctgcg gctgaagcgc taataaatgg ggtgaaagat agcgagaata
    13501 tgaaagagca atatcaaaca cgaagagact atctggtcca gcaattggcg cctttaggat
    13561 ttgaagtgac ccagccaaac ggtgcatttt acttgttttg caaactccca gctgccattc
    13621 aaactgactc ttggcagttt tgtgtagaat tagcggaaca ggcaaaagtt gcgtgtatcc
    13681 caggaattgc atttggccca gaaggagaag gttatatccg gatttcttat gctagcagca
    13741 tggaaaaatt acatgaggcc tgcaaacgga tcaaagactt tttaacagaa cagtgattca
    13801 tagattttat caaaaaaaca atcgttaatt ttgcggtata ttctgcaagg agacgattgt
    13861 tttttaaatt tagttcaaat gaacgcgttt cttttgattc ataactaatg taatgttaag
    13921 tttaaattgt ttagaatgat tttaaaagaa tattcaagga ggtttcatca atggaaaaaa
    13981 tcaaagttgt cattgtaggt gcatctcatg gagggcatca atcgatcttg gaactattga
    14041 cacgatacgg tgaaaatgta gatatcacgc tatttgaagc aggagactat atttccttca
    14101 tgtcatgtgg tatggagctg tatttagaag acaaggtaac agatgtaaat gatgtacgta
    14161 atttcagacc agaaaacttt ccgcaatcca atgttcatat tttaaataat cacgaagtaa
    14221 aaacgatcga tgccgataaa aaaacagtaa cggttactag cgcatcagat aacgaaacaa
    14281 aagaatatcc ttatgacaaa ttgattttga gttctggtgt caaaccaaac aatctgccag
    14341 taccaggagc agatctagaa aatgtctact tgatgcgtgg atacaattgg gcaaccaaaa
    14401 tcaaagaaaa attaaatgat ccggctatta aaaaaatcgc tgtcgtaggt gcgggttaca
    14461 ttgggatcga agcagcagaa gcaagccgaa aagctgggaa agaagtcgta ttgcttgatg
    14521 tgatcgatag acctttaggc acttatttag atgctgagat gacagatatt ttagaacaac
    14581 acctaaatga aaacggtatt gaagttttga caaatgcaaa aatcgaagct tttactggta
    14641 acggaaaagt tgaggcaatc aaaacaagtg aaaaagaaat cccagcagat ctagtcattc
    14701 aagctgccgg tgtgaaggca aatacagaat ggttaaaagg gatcgtcgac ttagatgaac
    14761 gtggctggat ccaaacaaat gaatacttgc aaacgaatct tccagatgtg tatgcagtag
    14821 gagatgctac acttgcttat tctatcccag cacgcaaaaa aatgccgatc gctttagcga
    14881 ctgttgcacg tagagaagca cgttatgtag taaaacatct ttttgaagaa gtaccaaaca
    14941 aaccgttcgg cggagtcgta ggttcctctg cattaagtgt ctttgactat cattttgcag
    15001 caagcggatt gaatagcttt acagcagcaa aagcaggagt agatgtacga gtgtcttatt
    15061 atgaagatac gttacgacca aaatatgtac cagaagaaca aggaaatcca aaagtgtcca
    15121 tccaattatt ctcggatcca atgacccatc aattgctagg aggagcagta ttatctacct
    15181 atgatgttac aggtcaagga aatgtattgg cactagcgat ccaaaacaaa ctgactttag
    15241 aagaactagc agaagctgac ttcttcttcc agccaggctt tgaccgacaa tggagcatgt
    15301 tgaatctagc cgctcaacaa gcgttaggag aagaaccatt tgtagaataa gaaaacgaaa
    15361 tatttgaaaa gaggttgtga aaaagctgcc ttgcatcaag taataagaac agccaagtaa
    15421 aaacagcttc ttatgttttt aacttggctg gacttattac cgcagatgca agcttttgaa
    15481 caccgtttat tttcaaaaaa gggactgtga cacgatttgt gtaccgaccc ccaaaagtta
    15541 gaccaaaaaa tctaactttt ggaggtcggt attttttatg gttaaatata cttttgaact
    15601 taaattaaag atcgttcatg attatttgga tggcaaaggc gattggaccg taaaaatcca
    15661 gatcaagaga ttgaagcgga aatgcttaaa attcgggaga agcacaagga ttatggctgt
    15721 ttacggatga ccaatgaact aagaaaccgc ggtttctcta tcaataaaaa gaaagttcag
    15781 cgcttgatca agaagctagg aataaaagta acggcataca cgcgtaaatc acgtcgctac
    15841 aattcttatc gaggaaaagt
//
LOCUS       DAZULR010000056        14167 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.057, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000056 DAZULR010000000
VERSION     DAZULR010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14167)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14167)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14167
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.057"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            126..827
                     /locus_tag="ACG8ZV_002231"
     CDS             126..827
                     /locus_tag="ACG8ZV_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HFS4997515.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMLGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            824..1945
                     /locus_tag="ACG8ZV_002232"
     CDS             824..1945
                     /locus_tag="ACG8ZV_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HFS4997516.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            1960..3192
                     /gene="pepT"
                     /locus_tag="ACG8ZV_002233"
     CDS             1960..3192
                     /gene="pepT"
                     /locus_tag="ACG8ZV_002233"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HFS4997517.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            3324..4232
                     /locus_tag="ACG8ZV_002234"
     CDS             3324..4232
                     /locus_tag="ACG8ZV_002234"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFS4997518.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            4267..4539
                     /locus_tag="ACG8ZV_002235"
     CDS             4267..4539
                     /locus_tag="ACG8ZV_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HFS4997519.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            4550..5596
                     /locus_tag="ACG8ZV_002236"
     CDS             4550..5596
                     /locus_tag="ACG8ZV_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhN family protein"
                     /protein_id="HFS4997520.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            5847..8456
                     /gene="clpB"
                     /locus_tag="ACG8ZV_002237"
     CDS             5847..8456
                     /gene="clpB"
                     /locus_tag="ACG8ZV_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HFS4997521.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(8607..9293)
                     /locus_tag="ACG8ZV_002238"
     CDS             complement(8607..9293)
                     /locus_tag="ACG8ZV_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997522.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(9271..9765)
                     /locus_tag="ACG8ZV_002239"
     CDS             complement(9271..9765)
                     /locus_tag="ACG8ZV_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HFS4997523.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(9785..11005)
                     /locus_tag="ACG8ZV_002240"
     CDS             complement(9785..11005)
                     /locus_tag="ACG8ZV_002240"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4997524.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            11152..12987
                     /gene="lepA"
                     /locus_tag="ACG8ZV_002241"
     CDS             11152..12987
                     /gene="lepA"
                     /locus_tag="ACG8ZV_002241"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HFS4997525.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEDEPKK"
     gene            complement(13081..>14167)
                     /locus_tag="ACG8ZV_002242"
     CDS             complement(13081..>14167)
                     /locus_tag="ACG8ZV_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4997526.1"
                     /translation="DINDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTD
                     TRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINA
                     EFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKII
                     SLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVK
                     NDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKED
                     GELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISI
                     TMDTYSHVTDKMRNETVDIMENLRKNS"
BASE COUNT         4581 a         2592 c         2933 g         4061 t
ORIGIN      
        1 aaataagaaa atgttgtttt atagaacgaa aaggtatatt ttttaaggag atatgggaat
       61 ttttttattc ctagtctcct tattttattt ggaaaatgct ataattatct agaaggagtg
      121 aagctatgaa ccatttagat ttatctcagc gcttagccgc agtgggtgac tttgtccctg
      181 aatccgctcg tttagcagac attggatcag atcacgctta cttacccgtt gcattgatat
      241 taagaggaaa aatcgaatat gcagttgctg gtgaagtcgt tcaaggtcct tatgaatcag
      301 cacgtaagca agtcaaaaaa gatggattag aagaccgtat caccgtacgc cttgcaaatg
      361 gtctagatgc tatccagcca caagatggta ttacagctgt cacgattgcg ggtatgggag
      421 gttcactgat ccgagatatc ctagaagctg gcaagttgaa tcaacgctta agcggacaag
      481 aacgtttgat ccttcagcca aacatcggag agcgtacatt acgatcttgg ctgcaagaaa
      541 atcagtataa aatccaatca gaaaaaatac ttgaagaaaa taaaaaaata tatgaaatca
      601 ttgtagccga aaaagaacaa aaaccagtta cttacaatga aatggagctg atgttagggc
      661 catttctgct tgaagagaaa agtgagatct tcaaatcaaa atggacaaga gagcttcaac
      721 aaagaaaagc tatccgtgaa cagctcaaac aagcagctaa tcaagaggca cgtcaaaaac
      781 aaatcgagca ggaaatccaa atgattgagg aggttttaaa gccatgacaa tcagcggacg
      841 cactttcatc caaaagtttg aaagctattg tcctcagtgg ctagctgaag aaggagaccc
      901 agtcggactg catatcggaa cattggataa gccaatccaa cgagtaatga tgacattaga
      961 cgttcgtcca gaagtggtcg aagaagcaat caagaaaaaa atcgatttgc tgattgctaa
     1021 acatcctcca atctttcgtc ctgtaaaacg gctggttact gatcagccac aagaaaaaat
     1081 gtatgcagat ttgttgaaac atgatattgc cgtctatgca gcacacacga acatggatat
     1141 tatttgggat ggactgaatg actggttttg tgaacttctc ggtattgaag tggagagtta
     1201 tttagtaaag actcatgaga ttcattataa aaaactggcc gtttatgtac ctgtggatca
     1261 tgcacagaaa atgcgtgaag tattagctgc agctggtgct ggtacacaag gtgattatac
     1321 cggtacaagt tttacctcga ttggacacgg tcgatttact ccggaagctg gtgcacaacc
     1381 agcgattggg aaagtaggga agacagaaca agttcaagag gcaaaagttg aggttatttt
     1441 gccggaaact atcgaaaaac aagtgattca agccatgcgg tcagctcatc cttatgagga
     1501 acctgcttat gatcttttcg ctatagatga accagtcgaa atgtttgggt taggacgagt
     1561 aggtgaattg ccgcaagaaa tttctataga ggcatttgta gaacaagtaa aagaagcgtt
     1621 ccaactagat ggactgagaa tagtccagcc aaaaaatgca aaatcctctg tgaagcgcat
     1681 tgcgatttgc ggtggaagcg gtgaaaaatt ttatccgcaa gcaatcgccc aaagagcaga
     1741 tgtctatatc acgggagata tctattatca tacggctcat gatatgcaaa gcgctgggtt
     1801 gattgcaatt gatcccggtc attatattga atcgttatgc aagcaacgat ttatcgagaa
     1861 atttgaatct tggaaacaag aagaaaattg ggatattaac tttttcgttt ctgaaacaaa
     1921 tacaaaccca tttcaattta attaaaagga gagaatacta tgtacgaaaa tcttttgcca
     1981 cgttttttac gatatgtcaa aacagaaaca cgctccgatg caacaagcaa aacgactcca
     2041 tcgactcaga cacaagttgc ttttgcgcaa gaattgaaaa aagaattaga agagttaggc
     2101 ttagctgatg ttttctataa tgaagataac ggattcgtta tgggaacatt accaagcaat
     2161 gttgatcatg aagtgcgttc cattggattt atttcccaca tggatacagc agattttaat
     2221 gcagtaggag tcaatccaca aatcattgaa aactatgatg gcgagtctac gatcgtacta
     2281 gatgcggaag aacgctatac attgaataca aaagattttc caaatttgaa aaattatgaa
     2341 ggccacacat tgatcacaac agatggcagt acattactgg gagcagatga caaatcaggg
     2401 attgcggaaa tcatgactgc aatggagatc ttgatcaata atccttctat ccctcacggt
     2461 accatcaaag tggcttttgg tcctgatgaa gaaatcggtg tcggagcgga taaattcgat
     2521 gttgagcaat tcgatgtaga ttttgcttat acagtcgatg gtggtccttt aggtgagttg
     2581 cagtatgaaa cgtttagtgc tgctcaagca aatattacga tccaagggaa aaatgtacat
     2641 ccagggacgg caaaagatac aatgatcaat gctctacagt tagcaatcga ttttcataat
     2701 cagcttccag ccgatgaagt tccagaaaaa acggaaggat acgaaggttt cttccatttg
     2761 atggcattgg atgggaatcc tgaagaagct tctatgagtt atatcattcg cgatcatgat
     2821 cgtgaaaaat tcgaagcacg caaagcacaa atcacacata tccaagaaga gttgaatcag
     2881 cgatttgatc aagaacgaat caaagtagat atgtatgatc aatattacaa catgaaagaa
     2941 atcattgaaa aagatatgag catcgtggaa ttagcgaaac aagcaatgat cgagcttggt
     3001 atctctccag tgatcgaacc agttcgtgga ggaacagatg gttcaaaaat ctcttacatg
     3061 ggtattccga cgccaaatct atttgccgga ggagaaaata tgcacggacg attcgaattt
     3121 gtttctttac aagtaatgga aaaagcaaca gacgtgattg taaaaattgc agaattgaac
     3181 acaaagagtt aaaatcgaaa aagaacagct tatgacaagg cgttcgtccc aatgatggaa
     3241 tgtcatctgt ctaaggctaa agggcaggac aatggaattg gttgtcccgc cctctttttt
     3301 gaagagtaaa taggaggtaa agaatggaaa agctgctagt tttttataac aaaagttcag
     3361 ggaaagatga gggtgagaaa ttagcacgct ggtttcaaga ttatgtaaaa gaaaagcagc
     3421 cagaattata tgtagaacta gctgaaactg gcccatcgat tgatgatgcg gaattagtca
     3481 agaaagcaga agccatagaa gctgatactt tagtaattat aggtggagac ggcacgattc
     3541 atcatatcgt ccaagcgttc caaaaaacat tatctcaata ccatgtcgga ttacttccag
     3601 gtggaactgt caacaacctt gcacgtgttc ttgagattcc cctcaaaaaa gaagaagctg
     3661 ctgacgtgat cctggaaggc aatgtacgga aaatagacta tggtcaagtc aatgatgaag
     3721 tcattatctc tacactgaca atcggaatct tagcagatac agcagtttgg atcagtcaag
     3781 aagaaaaaca gcgttacggc tcgtggatct ttatcaagaa gttttttaag ttattgctga
     3841 agaagaaaaa atatcatttg gatttagaaa cagacgagga gcattggaaa ggaaaatccc
     3901 aactgttgac agtcacgatg tctaactccg tgggcggttt tacaaatttt gacgactcag
     3961 cgaccctaga tgatggaaaa tttcatgtaa cgatcgtacc ttccttagat attttccgat
     4021 ttatttttta tttgcctaga atcatgagag gcaaattcta tacgatcccc ggcattactt
     4081 atttcacagc caaacgcatg aaaatccaag cgcaggaaaa atctgtgggc actcgaacgg
     4141 atggagacac gacagatgat cttccagttg aattatctgt tgtatcaaaa ggattaacag
     4201 tttattcacc aaagaaagaa gaaaaagctt agaaatagta gttaacagaa agttggaaga
     4261 agagtaatgg atgtattgtt acacaatcct ttgtggtttt accttttcat tgtgaatttt
     4321 tacttatttt gtctgatggg gtatgataaa catcaggcta gaactagcgg ctggcgtgtt
     4381 cctgagaata atttgatatt tgtcagcctg ttaggcggtg gtttgggagg attgatctct
     4441 cgaaaagttt tccatcataa aactcggaaa aagaagttta ctataggatt cgctgcaggt
     4501 gtacttgttg atttgattct catttatttt ttccattaag gagcaggaga tgtcgtctaa
     4561 aggaacgaaa actaaaatca ttctgaatct gcttttgctg attgtgattt ttgccattat
     4621 ttattattta atcaatcaat catttgcaga tatctttgcc gaattgctgt ctaccagtgt
     4681 tgttgttttg gcagcggctg ttatattagg gacagtttac caaatcgctg aagggcgctc
     4741 aatcaaagaa attgctgaac ctttcgcgcc gaattttaca acgaaagatg ggttcttgac
     4801 ctctagctat attgcgtttt accgaatcgt ttcgtttggt acaggaacgc tgatctcgga
     4861 gatttatttt tataacaaaa aaggaatgaa gctatcccag ggagcagggg tgacagcact
     4921 ccatatgatt atgtacaaac tggcagtgat cacttatgca ttagctggct tggtcatcca
     4981 attctctctt ttttattcta atggtccatc aatgatctgg tttatcatcg ctggtatcct
     5041 tttgacgatc gtgattgttg cctttttatt ggcgatgtcc gtcagcttga atgttcaaat
     5101 attttttgtc agcttatcga ataagttatt taaaagtgag cgtttgcgga aatgggtgga
     5161 tacatgcaat cagcagatct actctttaag ggaaacggtc caaaccatta tccaagacag
     5221 gactgcgcta ttgcggattt atctatggaa tatgttaaaa cttgtatttt ggtatgtact
     5281 tccttatttg attctgattg aaaaccatcc taaaatagat tttctactga ccatttcgtt
     5341 tatcagcttt gcagtagtgc tttcaggggt tattcctacg cctgctggta ttggttcctt
     5401 tgaatttgtc tatttgttat tattcagacc agttgttgga acagttgacg cagtttcttc
     5461 gcttttactg tatcgtttca gttcctttat cttgccattt ctctatggat ttgtgtatgt
     5521 gattgctgaa cggcgaagag tgatcaaaga agaaataata gaagtaaaaa aagagaataa
     5581 agaaaatcaa gggtaggtct tttataagat ctaccctttt tatcaaatca aagaaaaacg
     5641 ttatggataa gataatttta cgtttgtttg gctctttttt tatatacata caatcaattt
     5701 tgttttttta agatttatat aagtcgagaa aaaaagtcaa aaaactatgt gtatattttg
     5761 accaaaattg accaaagcga tataatagtt tttgtaaaga tcaaagaaat aagtgatctt
     5821 acctttaatt aggagggtat acctgtatga atattgagaa aatgactacg acgcttcaag
     5881 aagcgattgc tgaagctcaa cagattgcgg tcactcgaaa acatcaagat atcgacattg
     5941 cccatgtatg gaaaatcttt ttacaatcta atcattttgg tcgaaatttc tatacggatg
     6001 ccggattgga tgtcgaatct tttgaacatg aaattgatcg tctactggat gagtatccag
     6061 ttgtttctgg tggaaacgtc caatatggac aaaacctcag ccagaatttc tttcgattat
     6121 tgaatgaagc agaccaaata cgtgaaagct tcggcgacga gtttctttca acggaagtcg
     6181 ttattttagc gttgatgaaa ttaaaaaatt atccgttaac tgtttatttg aataaaaacg
     6241 gattatctga aaaagaattg cgtaaaaaca tcgaagagat gagaggagga gaaagagtga
     6301 cctcacaaaa ccaagaagaa caatacaaag cattagaaaa atacggcgtt gatttagtac
     6361 agcaagtcaa aagcggaaaa atggatccaa tcatcggtcg tgatgaagaa atccgtgatg
     6421 tcatccgtat tctttcacga aaaacaaaaa ataatcctgt tctgatagga gaacccggtg
     6481 tagggaaaac ggcaatcgtt gaagggcttg ctcaacgtat cgtacgcaaa gatgtgcctg
     6541 aaaatttaaa agataaaacg attttttcat tagatatggg tgcattgatc gctggagcaa
     6601 aattccgtgg tgaatttgaa gaaagactaa aagcagtctt gaaagaagtc aaaaaaagtg
     6661 atggacgtat cctcttgttc atcgatgaaa tccacaatat cgtaggggca ggaaaaacag
     6721 aaggaagtat ggatgccgga aatctgttga aaccaatgct tgctcgcggt gaattacatt
     6781 tgatcggtgc cacaacttta gatgagtacc gtcaatatat ggaaaaagac aaagcgttgg
     6841 aacgtcgctt tcaaaaggta ttagtcaaag aaccaacagt ggaagatacg atcagtattc
     6901 tgcgtggatt aaaagaacgt tttgagatcc accatggtgt taacatccat gacaacgcat
     6961 tagtagcagc agctacttta tctgaccgtt atattactga tcggttctta ccggacaaag
     7021 caatcgattt gatcgatgaa gccagtgcaa cgattcgggt agaaatgaac tctatgccaa
     7081 cggaattaga tcaagttact agacgtttga tgcagttgga aatcgaagaa gctgcactga
     7141 aaaaagaatc agatgatgca agtaaaaaac gcttgaaaaa tttgcaagaa gaattagctg
     7201 aacttcgtga agaagcaaat gcgatgaaga tgcagtggga aacagaaaaa gaagaagtca
     7261 attctgtttc agcaaaacgt gctgaaatcg ataaagcaaa acacgaatta gaagatgcag
     7321 aaaataacta tgatttagaa cgcgctgctg tattgcgtca tggtacgata cctcaattag
     7381 aaaaagaatt gaaggaatta gaagctaaag caaaagacag cgagattaag atggttcaag
     7441 agtccgttac cgaaaatgag attgctcaag tcgttggcag attaacgggt atccccgtaa
     7501 cgaaacttgt agaaggtgaa cgagaaaaac taattaaatt gaatgaaaca cttcataaac
     7561 gagtgattgg tcaagatgaa gcagttgatg cggtcagtga cgcggtaatt cgttcacggg
     7621 ctggattgca agacccaaat cgtcctctag gttctttcct tttcctagga ccaactggtg
     7681 tcggaaaaac cgaattagcg aaagcgttag ctgagaactt gtttgactca gaagatcata
     7741 tggtacggat cgatatgagt gaatatatgg aaaaacatgc tgtgtctcgt ctagtcggag
     7801 ctcctccagg ctatgtaggt tacgaagaag gtggtcaatt aacggaagct gtcagacgaa
     7861 atccttatac aatcgtcttg ttggatgaaa tcgaaaaagc gcatcccgat gtcttcaata
     7921 tcttgttaca agtcctagat gacggacgct tgactgattc aaaagggcga gtagtagatt
     7981 tcaaaaatac ggttctgatc atgaccagca atatcggttc acagttactg ctggaaggcg
     8041 tgactgctga tggaacgatt ccagaagcag tggctgaaca agtcaacacg ctattacgtg
     8101 gaaacttcaa accagaattc ttgaaccgaa tcgacgacac gattttattt acaccattga
     8161 gcctagacaa cgtgaaagga atcgttgaca aaatggtggc gcaattggca caacgtctgg
     8221 aacatcaaga aatcctgctg acaatcagtg atgaagccaa aacgtggatt gctgaaaatg
     8281 cttatgaacc agcatatggt gcaagaccat tgaaacgatt tatcactaag gaagtagaaa
     8341 caccactagc taaagaaatc gttgcaggac atgttatgcc taaatcaaaa gtaacgatta
     8401 ctttacttga tggacaactt catttcaaaa cagaagagct agaagaaatc gtctaatctt
     8461 ccattgagac tataaaagaa aaaaggggtc tgacacaact agtgtcagac ctcctttttt
     8521 caaataaaca gtgttccaga agtagtttct tcgaaaaata agccgaaatt tcttgaagct
     8581 gcccgcttct gtcacaacct cttttattag gtatttttca ctttttctaa tttataactt
     8641 tcaaagtaac gctcatcttt tttactttga gaccatgcaa acaatcccat taaggcagca
     8701 cctatcgtat ttgtcagcaa gtcgcccatc gtatccatca atgctgctcg tccgacaaac
     8761 agtgtgccat cagaagcagc aaaacgttga agattcatgc ctaagaactg gtcgcataag
     8821 aattcccaga actcccaaaa cacgccgcaa agtccagcaa acgcaaagcc gaataagagg
     8881 aacaaccaag gactggtttt tgatatctca gcatctttca tcaagtaacc aatcaatcca
     8941 tagccaagag ctgtcaggac cattggactc accgcatgta agattttgtc ccaaaaagag
     9001 atgatactga tcaaatgcat ccctgtgcct aaaaagacag agatgaacaa gaaaaaccag
     9061 taaaacaaaa cgattgctgc tggtatttta agtttgaaaa ctttcaaaat gacttgtggc
     9121 atgaaaatca atgcaatccc taataaagat tccacgataa atgtgattcc ttgagaagtc
     9181 gaatattttt gtgtgataaa ttcataaaaa ttatagcaga caacgaatac accaaaagca
     9241 agtaaagcta tttgcacctt tttgatttct ttaatcactg aaagtccctc catctaaaaa
     9301 tctttttact tctgaaagca actcaatttc tgaagaaacc acttttccgt tcaatttgat
     9361 caaacctatt gtatataagt tcaggtagtg aaattgattt tcagctgttt cttgtagtgc
     9421 agcgattttt ttcgggtggg ttccgccttg ctgtcgagta tcagtatata agccgatcac
     9481 tgggatgcct ttcgcataag ccacaccgat ttccgatgct accccggcat cgatcgtcag
     9541 cccatctagt aaagcaatca ttaaatcact agccaacact ttttctgtgt cagcaagagc
     9601 aatcattcga ctgtctgcat aagcagtttt gtcattgatt gcttcatttt cttgaggaag
     9661 atagatcgaa agctcagaag agagctctct gatttcttta actaactgtt ggttatataa
     9721 caaatcactt ttagcaaaca ttggtgcggc aaaataaatt ttcatctaaa catcatcctt
     9781 tttatcaaaa ataatcgcta aagtaagctt ccatgtttgg aatgatacgc tctagtgact
     9841 tcagtgtttc ttcatctgtt tctaaccgtt cgattcttgc caaataagaa gcacggcgat
     9901 aattcatcat caagcaagtc aatgtttgga tatccagtcg aacggatttt cctataggtt
     9961 catttaagac acggacttgt ccctgttcat cccatgttaa agcgaagaca ccattattcc
    10021 aaggagcgac aggatcttca atgatgaaat gaaaagcatc agctgttcca acaaacggaa
    10081 accgttgaag gaattctttt acatcaacga tccgagccat aaaatatggt tcgatctgct
    10141 ctttgatctg actatcttca atcaaaaatg ctaaaggctc atttttataa atatctccat
    10201 gtacccagta gatcatggaa aaatgtgcgg aaataaagtt ccataagcca tttcgagctt
    10261 cttgatcaag atagaacatt tcttttacgt gaaatatttc ttcagctacc cagtagaaca
    10321 gaacacctct tggttcatgg ttgctatcgt agtagacagc ggctgtgcgc tcatcttcat
    10381 tttcgaaacg ccaatactct tcccaatgaa aatcactgcg gaataaagca ccatggtttt
    10441 gttgggcaaa tttgtcataa acggaaaata cgtctggatg atcaactggt aatcgctcaa
    10501 ccataccact tactgggatt tgtttaggta gctgtgtatc tctgatttta aaggaaagtt
    10561 tatcagacat gatttcccat cctttacgcc gatagtaggg gatactgtaa ggatacaaat
    10621 aagagatcca ttgcttattc ttgcgcatat tatccaatgc aacgataatt agatcttgca
    10681 tcaatccatg gttagcatat tctggataag ttccaactcc agtcacacca cccattttat
    10741 aacgtgcacc gtgaatattg acttcacaag gatagatagc gatttgagag atcagtttat
    10801 tttcgtggaa ccatccgaac actttcgata cttccaaaat cggttttttg gaacggataa
    10861 aagctcgttt attctcaaac ccgctttcct cgatgtctgc ttcagtcact tggaacacat
    10921 aggaaagcaa ttcattgaat tgatcgatat gttcttgagt gaccggtttt aattcaagat
    10981 tttctctaaa atctttttga tccatttttt catctccatt tattagcttg ataacagtat
    11041 agcaaaattc tacaaaaaaa acttctatag ctgactaatt aaaaactctt taaattactg
    11101 cttttcgttg gtataatgga aagtgctgat tatatgaaaa gaggagacgc tatggatata
    11161 aagaaaatga aagaacgcca agagcagatt cgtaattttt cgatcatcgc tcatatcgac
    11221 catgggaaat ctacattggc cgatcgtatt ttagaaatga cgcacactgt gacgtctcgc
    11281 gaaatgcaag atcagctgtt agactcgatg gatttggaac gtgaacgtgg aatcacgatt
    11341 aaattaaatg ctgtagaact caattacaca gcgaaaaatg gagaaacata tatctttcac
    11401 ttgattgaca ccccagggca cgtcgacttc acctatgaag tctctcgaag ccttgctgcc
    11461 tgtgagggtg ccgttttagt ggtcgatgca gcacaaggaa tcgaagcaca aacattggcc
    11521 aatgtttatt tagcgttaga caatgatttg gagatcctgc cagtcatcaa taaaatcgac
    11581 ctacccgcag cagatcccga acgtgtccgt caagaaatcg aagacgtaat cggaatcgat
    11641 gctagtgaag ctgtattagc cagtgccaaa tcagggattg ggattgaaga tattctcgag
    11701 cagatcgtgg aatatgttcc tgcaccaagt ggagacttag atgcaccgct aaaagctttg
    11761 atctttgact ctatttatga tagttaccgc ggtgttgttc taaatgtccg gatcacggac
    11821 ggtatggtca aacccggaga caaaatcaaa ctgatgagta atggcaaaac atttgatgtt
    11881 acagaggtcg gggtcttctc gccaaaagca gttgctagag actttttgat ggtcggtgat
    11941 gtcggttata tcacagcaag tatcaaaact gtccaagata cacgagtagg ggatacagta
    12001 acgttagcag acaatcctgc cgctgaagct ttaccaggtt accgaaaaat gaatccgatg
    12061 gtttattgtg gtctttatcc aattgatact tctcgttaca acgatttgcg ggaagcttta
    12121 gaaaaactgc aattgaatga tgctgcttta caattcgaac cagaaacctc tcaagcatta
    12181 ggttttgggt tccgctgtgg attcctcgga cttcttcata tggatgtcgt ccaagaacgc
    12241 ttggaacggg aattcaatct agaattgatc acgactgcac catccgttat ttaccatgtt
    12301 aataaaacgg atggtacgac tgctacagta gataacccgg cagattttcc tgaacctgta
    12361 acgattcagg atgtagaaga accattcgtc aaagcacaga tcatggtccc aaatgatttt
    12421 gtcggtgcag taatggaact ttctcaacga aaacggggag aattcattac gatggattat
    12481 ttagatgatt accgagtaaa tgtcgtctat aatattccgc tttctgaaat tgtctttgac
    12541 tttttcgaca aattgaaatc aagcacgaaa ggctatgcct cattggatta tgaaatgtct
    12601 ggttatcaaa aaagcaagtt agtgaagatg gacatcttgc tgaatggaga aaaagtcgat
    12661 gcattaagct ttatcgttca ccgagacttt gcctatgaac gtggaaaagc aatcgttgaa
    12721 aaactgaaaa aactaatccc acgccaacaa tttgaggtgc caatccaagc agctattgga
    12781 caaaaaatcg ttgcccgttc agacatcaaa gccttgcgta aaaacgtctt ggctaaatgt
    12841 tatggtggag atgtttctcg taaacgtaaa ctcttagaga aacaaaaaga agggaagaag
    12901 cggatgaaac aaatcggctc cgtcgaagtt ccgcaagaag ccttcatggc cgttctgaaa
    12961 atggacgagg acgaaccgaa gaaatagcaa gggtttgttt gaaaacagtg taaaaaataa
    13021 accatgttta catggatttg ccaccggttt gccaccggtg gtttttttcg gtggcaaaaa
    13081 tcaagaattc tttctaagat tttccatgat atcgaccgtt tcatttctca tcttatctgt
    13141 tacatgcgag taagtatcca tcgtaattga aattctgctg tggcccaatc gttcagagat
    13201 ttctttcatt tttgcgccat tttcgagaag aagtgtagca tgagtatgtc tgagagaatg
    13261 gaagttaaaa gagagggaga gtgcattcga tatcctccta gtattccatt tcactacact
    13321 tggcgtaact agctcaccgt cttccttcgt acatactgca tttgaatcaa tgtagagctt
    13381 tccatacttc attcgatttt ctaattgttg tttcttatgt tttttcagaa ttgctagcaa
    13441 ggtttgtcca ataaaaatcg ttcgattgga actgcttgtc tttggcgtac catataccca
    13501 tgcgccgtca ttctttacca tttgtttctc tacagtaatt gttccatttg aaaaatcgac
    13561 atcatcccac gtcagaccac aaacttcgcc aacgcgcatt cccgtataaa atccaatatt
    13621 caaaggaata tagaaaggat gtccttcagg agtaatttct agcatatgat caaagtcctc
    13681 aagagaaatg atttttagat cttttttagt cgttggtcgt gcttcatatt ttggtatttt
    13741 tacatacagc ataggatttt gcttgattaa tccccaagga taaaccgcca tattcagcgc
    13801 attcttaagg acagagtgag taatagtcat tgttttcttc gagtaaccct ttttaaattc
    13861 agcattgatg aaattttgta aaagagcagg ggagagatcc gtaagttttt tctttcctaa
    13921 ataaccgttt atatgatttt tgatggtaaa tcggtagttt tcataggtat tgtattttag
    13981 atttagttta acgtattcct ccatccaaaa atcaaggtat tgttttactc gagtatccgt
    14041 acctaaaaag tattgtcctg tttcgtcaat atctgataaa acttttcgta aagcagcttc
    14101 ggcctctggt cgggtgtctc cgccaacttt ctccactttt tttcttgagc catcatcatt
    14161 gatatct
//
LOCUS       DAZULR010000057        13947 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.058, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000057 DAZULR010000000
VERSION     DAZULR010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13947
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.058"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..99
                     /locus_tag="ACG8ZV_002243"
     CDS             <1..99
                     /locus_tag="ACG8ZV_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail adaptor protein"
                     /protein_id="HFS4997527.1"
                     /translation="IVIDSMRYNVIYADYDNFYIYFYLESVGEYGD"
     gene            89..490
                     /locus_tag="ACG8ZV_002244"
     CDS             89..490
                     /locus_tag="ACG8ZV_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997528.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            483..887
                     /locus_tag="ACG8ZV_002245"
     CDS             483..887
                     /locus_tag="ACG8ZV_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997529.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            899..1507
                     /locus_tag="ACG8ZV_002246"
     CDS             899..1507
                     /locus_tag="ACG8ZV_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4997530.1"
                     /translation="MAKTKTVVTTFDNVSIKRIAFNFKNAGNAIATNCNGQLDGETEM
                     QTVVKKCGATEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDGRIKPGIYSYGPDSV
                     GEDFSLAAEIVDDFEENRKLVGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFG
                     KFYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            1527..1889
                     /locus_tag="ACG8ZV_002247"
     CDS             1527..1889
                     /locus_tag="ACG8ZV_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997531.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            1892..2074
                     /locus_tag="ACG8ZV_002248"
     CDS             1892..2074
                     /locus_tag="ACG8ZV_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997532.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
     gene            2091..5522
                     /locus_tag="ACG8ZV_002249"
     CDS             2091..5522
                     /locus_tag="ACG8ZV_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFS4997533.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNEIDKTSNALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     ATAGQSASEAEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLSKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDFIVAIGGLTAAFGILLPAILAVSYLFGPMML
                     IIGGIIAVIAGVIVAIKNWGAITDWFSGLWKKFTDWLGDTWESIKDGASSVWDGVKET
                     WSGFVDWVQDIWQGVSDWFGELWSGLVEGASNIWQGVQETWQTFVDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWISIAWNGIVTTFHTIFDPVVAWWNGIWTAISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWNSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISGIFDNLNISIPHIPLPEFIMEGSF
                     NPLKGQIPHLRVKWHAKGGIFTKPTLLGGMNGVGEAGPEAVLPLKRSVLQEIGDRILS
                     STSVSSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKIQNDNASAWR"
     gene            5573..6310
                     /locus_tag="ACG8ZV_002250"
     CDS             5573..6310
                     /locus_tag="ACG8ZV_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFS4997534.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVAGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINHFNCTGLSKIQIYRNGLR"
     gene            6320..8611
                     /locus_tag="ACG8ZV_002251"
     CDS             6320..8611
                     /locus_tag="ACG8ZV_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail spike protein"
                     /protein_id="HFS4997535.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYSINGTNADLIVDGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITATQAWQNAKVLAKPAIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKSLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNGGEISDLLNDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYETAWTLDGGFNASFITAGEIVGITIRGTTLISDGADYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYVTSGDGSSLSINGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDNGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDIRLKEDTAYDSTVLDQKRF"
     gene            8635..10761
                     /locus_tag="ACG8ZV_002252"
     CDS             8635..10761
                     /locus_tag="ACG8ZV_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997536.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDNVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFMAEIKGRVDSLNQQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSIDFGDYDYSENPNLMPYITEPWVG
                     PLLGNGHTVKDSVKRVITHTKTRTANSGDILSLGLGIPCTAEANNRYLITTLRPSTTY
                     TLSVTMSVGSDWTGETNTIGVRLRYLNEQGGIELPINALIPANVERDKMVTHTFTGIT
                     KDNVTSITNCYVEIFSLNSEYKGTVSVSYDVKLKAHYPNLLDGPYWLGKVPLGENIAD
                     PTVVFPHKTSEYMVYGRRNTENYIADQTYTISMKATKLTVQSFAVYIAAGRVKVGDMK
                     PTEGLANTWELTFTVTKQHIDSGVTNYLEIYQYPSATKGAVQIEWLKLEKGNTRTPNI
                     SEYKYRGTGMRDSNNPKDYVWDLAPEYVEDNLATDIKISEITGKANNYTDGKVSEINS
                     QLTASINEVDTTAKDAQTKANANATAIDELDNKIDERINDTATTTLTVTNGNTGSAKL
                     YREGKTVSIYFVALNGKSSGGNDSTILTIPEGYRPPISFEQLVGSIDRSTLNSAQLSI
                     GADGAIKWRRNSSYGSDYTFAITYTI"
     gene            10778..10927
                     /locus_tag="ACG8ZV_002253"
     CDS             10778..10927
                     /locus_tag="ACG8ZV_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997537.1"
                     /translation="MKAAYRPIEPYGFEQIIVNDEEHLPEECTEVEPPIPNWKPKFNY
                     WEGNK"
     gene            10924..11370
                     /locus_tag="ACG8ZV_002254"
     CDS             10924..11370
                     /locus_tag="ACG8ZV_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997538.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGIRADGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYESLENENGDLKQINAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            11372..11509
                     /locus_tag="ACG8ZV_002255"
     CDS             11372..11509
                     /locus_tag="ACG8ZV_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HFS4997539.1"
                     /translation="MFSFSDVKMMYDWGCFTNEQVMVFVPLCITEEKADKIISKEESA
                     S"
     gene            11547..11840
                     /locus_tag="ACG8ZV_002256"
     CDS             11547..11840
                     /locus_tag="ACG8ZV_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997540.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHAEKLVEHTQQIKTLFRERRK"
     gene            11837..12061
                     /locus_tag="ACG8ZV_002257"
     CDS             11837..12061
                     /locus_tag="ACG8ZV_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HFS4997541.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            12058..13083
                     /locus_tag="ACG8ZV_002258"
     CDS             12058..13083
                     /locus_tag="ACG8ZV_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition family protein"
                     /protein_id="HFS4997542.1"
                     /translation="MKKKITITAMSLLTALFLLPINTFAYTINDEYNLAPNQGDSRLA
                     IPNKIILHETGIDAPARNVAANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAG
                     NANPYAPVQIELQRTYDKALFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIIS
                     HLWVTNYVWGNHTDPYGYLSQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGA
                     ANPTLTDGTNHAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADG
                     IYRPDVNQAYNTSGNVGYHVSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRW
                     YLNIPKR"
     gene            13273..13346
                     /locus_tag="ACG8ZV_002259"
     tRNA            13273..13346
                     /locus_tag="ACG8ZV_002259"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13307..13309,aa:Ile,seq:cat)
BASE COUNT         4847 a         2182 c         2904 g         4014 t
ORIGIN      
        1 atcgtaatcg atagtatgcg ttacaacgtt atctatgccg attacgataa tttttatatc
       61 tatttttatc ttgaaagtgt gggtgaatat ggtgattgat aattctaaag aaaaagaacg
      121 tttaaataag caaatttctg ctatcaaaac ttccttagaa gagcattttg gcctcaaact
      181 ctttcaagac tccgtaggcg aggatgagct acctgatgat tttaattact tcattctcga
      241 aacaggagaa atagaaatga tcactgagcc aaaatatagc gtgggtcaaa atctatatct
      301 aactttctat tcagaaaata gagaagattt aacaggagac tcactagata ttatttcatt
      361 gattcaaaat cgttcgattc gttttcagag aatggatccc aatcatttaa aactagagaa
      421 ccaagatcgc tatatcgatc aattggtatt tacgtttaga cgattattga agagtgattg
      481 tcatggctaa aaatagttgg gagctaaaaa taaatggaca tgatgaactt cttgtgcgga
      541 tggaacgcta ttcaagcgag agcgaacgac tgattaacga agcattgaaa tcaaaaggtt
      601 cggctattgc agtggatagg attacagaaa aaattcctgt ttctgaagca gatttaagaa
      661 gagggcacca acacgcaaaa aatagtcgtc cacttaagac tcaatacatt aatttgggtt
      721 tcatcattag acctacaaga aaatttgagt atttaaaata tcctgatttg gggataggta
      781 cttctaaaag aaatcagccg gacgaattta tgagaagagg attaggtctt gcacttgatc
      841 caattacaga acttctgatt cgtcaattcg ataaattaaa taaatagggg gaacaacaat
      901 ggctaaaaca aaaactgtag taacaacgtt cgataacgta agtatcaaac gaattgcttt
      961 taattttaag aacgcaggaa atgcaatcgc aacgaattgt aatggacaat tagatggcga
     1021 aacagaaatg caaacggtgg ttaaaaaatg tggagcgaca gaagtaaaat caaaatctaa
     1081 accaatcaat atgacggtaa caattactgc acatgtaccg atggaagttt atcgacgttt
     1141 caatgggttg aaacaagatg gacgtattaa accaggcatt tactcttacg gtcctgattc
     1201 cgtaggcgaa gatttctcac ttgctgcaga gatcgtggat gacttcgaag aaaatagaaa
     1261 gttagttggt atgttagcat gcacttcgaa tacaggatta acattctcta ttgaaaatgg
     1321 tgcggatgaa gtagctgcgt tagaactaga aacaaaagtt atgcaagatg aatttggtaa
     1381 attttatcat gaagcaattg ttgcagaact tgaagaagac ttaacagatc aatggatgac
     1441 gaatctatct gctgatgtga ttaaaaaaac ttcagttgtg acaactacgg ccactcaatc
     1501 acagtaaaaa aaacggaggt agcgaaatga acgaagatta ctcaaaaatt gaactaaacg
     1561 atggaacaat tttgaattta gaacctaaac tgaatatcaa gaaattattg atgatcaata
     1621 gagattttaa cacagacgag tttgcaaaaa tgactgtggg aaaaggatcc atggatattt
     1681 ctgttattca aggtgcaaag gctgtgtata ttgcttaccg ccaagcgaac atgactgatt
     1741 atatttcatt cgatgaattt atcgataaat gggattttga tatggctact gccagctata
     1801 tttatcaatt gatgatgttc aaacaagcac gcgatgctta tcaaaaagaa tttgaaaaag
     1861 caaataagga aaaaaagctt caaaagtaaa aattccaaag ctcttagttg aaacgtgggt
     1921 cgatgtctat tcgatgttga ccgacgtttt ttctatgcct tcagatttgg ttttaagcga
     1981 tatctgttta gatgacattt tgcaaatggc ttacaacaag agtgcttatg aaggatggaa
     2041 aaactatgca ataaaccaat cccagaaaaa ctaaagaaag gaggtaaaaa atggctaaaa
     2101 agagaacaga agcagaagta actttcatag ctaacgatga cggattgaaa tctacgttaa
     2161 aagaaatcag tgctgaatta actaaaaata gagcagaatt aaaactagaa caagctcaat
     2221 tacaacagac tggttctgaa tcagacaagt taggaagtaa attatcttct ttagaaaagc
     2281 agtatgaatt acaaagtcaa aaagttgaag taactagcca acgtttagcc aatgcgaaaa
     2341 aatattatgg agaaaattcc accgaagttc agaaacttga aagagaactg attaatcaac
     2401 aaacagcgca acaacgtttg tcaaacgaaa ttgataaaac gagtaatgca ctagctcaag
     2461 caaaaggcga aatacagacg tacgagtcta caatgcaaca gttggatagc gaacaaaaaa
     2521 atgttcaagc tagtgcttct ctgattgaat ccgaatacaa aaaatggcaa gcaactgctg
     2581 gtcaatcagc ttctgaagcc gagaaattag cgaaagccca agaatatgtt tctcaacaat
     2641 ctgaaaatgc ggagaaaacg atagatatcc taagacgaca gttagaagct acacagtctg
     2701 aatttggcgc tacatccaca gaagcaatgc agatggaagc gaagcttaat gatgctgaac
     2761 gtgaatttga agagttagga caagctgcta aaaatgtaga tacaactaac ttggacgata
     2821 tcggaagcaa aatagatatg aataatttaa tggaagcttc tgacgtttta agcgacattg
     2881 gcgataagct tacagaatta gggaaacaag cagtggactc tgctaacagt gtaggtagtt
     2941 cccagagtaa gatacaagct aattttggtt tgtctaaaca agaggctgaa gaattaacga
     3001 atgtagccag agacatttat tataaaggtt ttggagaatc gttagatcag tccacagatg
     3061 cattgatttt ggtaaagcgt aatttaggag atttaaataa tcaagattta caaaatatca
     3121 cggaacaagc tatggtccta gaaaacacca tgggcgctga tatggatgaa acgttacgtg
     3181 gtgtaaatgg cttaatggtc aatttcggct tgagtgctca agatgcaatg gatttaatgg
     3241 tttcgggtac tcaaaacggt ttagataaaa cgcacgaatt aggcgacaat atggcagaat
     3301 atagccaatt atggagtcaa atgggatatt cagctgatga aacgttcgga atgcttcaaa
     3361 atggtttaga tgcgggtgct tataaccttg ataaagtcaa tgacttagtt aaggaaatgg
     3421 gaatatcgtt aacagatggt cgatttgagc aaaacatgga tatgtttagt gaaagtacta
     3481 gaaaagcttt tgaagagtgg aaaaatggcg gaggaacaca aaaagacgtt attaattcca
     3541 tgattcaaga ttttagcaat atggatggtc aatacgacca attaaataaa gcttcgacaa
     3601 tttggtctgc gcttggcgaa gataatgcga tgaaagttgt ccaatcttta actgatgtta
     3661 accatacatt tgatgatgtt agtggatctg cacaaaaaat gaatgaagat tctactactc
     3721 cgttgcaaga gttgaacggg aaaatagctg aattaaagga ttcattagct cctataggca
     3781 acacaatcat agatgcactc gaaccagtaa ttgattttct aggaaagatg gctgatgcgt
     3841 ttaataatct tccacaacca gtacaggatt tcattgttgc tataggtggt cttacagcag
     3901 catttggcat actgttaccg gcaatactag ccgtgtcata tttatttggt ccgatgatgc
     3961 ttataattgg aggaattata gctgttatag caggcgttat tgtggcaatt aagaactggg
     4021 gtgcaattac tgactggttt agtggtttat ggaaaaaatt tactgattgg ttgggtgata
     4081 cttgggaaag tataaaagac ggagcctcat cagtttggga tggggttaaa gaaacctggt
     4141 ctggatttgt agattgggtt caagatattt ggcaaggagt ttctgattgg tttggagagc
     4201 tatggagcgg attagttgaa ggagcttcca acatctggca aggagtccaa gaaacttggc
     4261 aaacattcgt tgattgggtt tcaaatattt ggaacggagt caaagaagta tggtcgatta
     4321 tttgggcaga cattgtagga attgttcaaa taccatggac attaataacg tcattgattc
     4381 aagctggtat taatattatc gtgggtattt ttgatgtagc tggacagtta ttgggcgcag
     4441 cttggcaagc tgtttggaca cctatttctg atttccttaa aaatacttgg gatactatga
     4501 cacaatggat aagtatcgct tggaatggga ttgtaactac attccatact atatttgatc
     4561 cagtagtggc atggtggaat ggtatatgga cagctattag tactacggct tcaaatattt
     4621 ggaattcaat tagtgcaaca gcttctagta tttggaacag tatcaagaat acaatcacta
     4681 gcttggtaca agcagctgct acagtaattc aaaatatttg gtcaactgta tctagttggt
     4741 taggtggaat ttggaattca atcagctcta cagcatcaaa tatctggaat agtgtgacta
     4801 gtagtataag caatgctata aacgcagcta aaagtgccat tcaaagtgtt tggaatagta
     4861 tatcttcgtg gattagcgga atttggaacg gtatcaaaaa tactgctttg aatctttgga
     4921 atggaattac aagcactatt agctctaaag taaacgatgg aaaaaatgca atttcaagcg
     4981 gttggtccaa tctaacaggt attgtttccg acatattcaa taatgttaaa agtacaattg
     5041 ctaacatatg ggaaggcatc aaaaagactg ttagcgctcc aattgattgg attagagaca
     5101 aaatcagtgg catttttgat aatttgaata tttctatacc acatattccg ttaccggaat
     5161 ttatcatgga aggcagcttt aacccgctaa aaggtcaaat cccccatttg cgtgtaaaat
     5221 ggcatgctaa aggaggtatc tttactaaac caactttact aggtggaatg aacggtgtcg
     5281 gtgaagcagg acctgaagca gttttacctt tgaaaagatc tgttttgcaa gaaattggtg
     5341 atcgtatctt gagtagcaca tcagtttcat ctagggcaca aacgattcaa cctgtgaata
     5401 actacgaatt caatttcaca attgatggta acgcagatga ggttactatg aagcaaacaa
     5461 ctcaacaaat cattgatagc attacaaaaa ttcaaaatga taatgcttcg gcatggcgtt
     5521 aaacaggaga gtatttctcc tgttttttta gtattaaaaa ggatgtgaaa aaatgactga
     5581 ttgtatacat tctataatcg atggatttcc tgattatttg cataaattgg ctttagctga
     5641 aagaccaacc ataccttctc caaaaagaca gagagttgaa acttctgttt taggtaggtt
     5701 aggtggctta gtacaagatt actcgtttga agatatgtcg tttacattgc actataacta
     5761 tttagaggat gtggaagacc atcaagcgtt caagcaatcg ttttatatca tgcgtcattg
     5821 gttaaactat gcaaagaaat tagaattctc tgacgatccc aacgtctatt acgttatcca
     5881 gactatcgat attggggatg cagaaaacga tattgttgaa tggggagagt tcgatgtaaa
     5941 tattactgcg aaaccattcg caagagttca agaagatgta cctataaccg tagataaacc
     6001 acagtcattt aacttgctga ataatagttt agaagaaagt tttccaaaga ttatcatcac
     6061 tccttcagct acttcatgcc agttcatctt aaatgattat gtgtttagtt tcgaaggctt
     6121 agtagcagga actgatgtag tcattgatag tgatttgatg ctttgctacg aagagcaatc
     6181 ggacggagat attttagatc ggtccaacaa aatgaagacc atgcaatatc cgacattgca
     6241 agtggatatc aatcatttta attgcactgg tttgagcaaa atacaaattt atcgtaacgg
     6301 gttaaggtag gtgaaataga tgatcgataa tttaataact atttacgata aaaatgacgc
     6361 gaataattta gctgaacatt tatatgatac gcaaggttta ggcgctttgt cagactggtt
     6421 aacagctact gttagcaata aactaaacgg agccgagata tttcagggta cttattcaat
     6481 aaacggaact aatgcagatt tgattgtaga cggacgtatt attcagtgtt atgtagatga
     6541 aaatcgagca aaacagcgtc tacggattta ttatgcaaaa acttctgtaa taggcaatac
     6601 gatagaagta aaagctgaac ctattttcaa tgatataaga aaatcggtgt tgaataaata
     6661 tgacagcgga acagaaaaga tcactgctac tcaggcatgg caaaacgcaa aagttttagc
     6721 gaaaccagct atcccttcgc agttttcttt ctcgtcatta gtagatacgc ttgctaatgt
     6781 gaagatagaa aaggcgaatt ttttagaatt ctttggtgga aaagagggat ctattctaga
     6841 tcgatttcat ggtgagtttc taaaagataa taacacatta cgtcatgaaa aaagtctagg
     6901 tacggatcat aaaatcaaag cgatttatac taaaaactta actggtcttg acttagagat
     6961 tgatgctcaa agtgttttag ttggagttta tccattcatt agcagctctt cagaaggaga
     7021 agacgagatc actctaccag aagaagttat tttcacggat tacgtggatg attatcctgc
     7081 tggatatgtt tcttttgttg attttaaaga caaagcgact gatgtagcca cattaaggga
     7141 agctgctaaa gactggttga aaacaaacat agataaacaa aaaccacaag tgagtggttc
     7201 gattgaatta gtaccattga ggcatcaaag aggctatgaa aaatttgttg atctagaaaa
     7261 agtttcgatg ggtgacggag tagatgtgta tcatccacag ttaaaagtga atatgtcagc
     7321 gagaattgtg gaatatacgt ttaatgttct aaccaattca tacgataaat tagttgtagg
     7381 aaacgtcaaa acaaacttct tagaaaacac agagaataat gtcagcaatt tgattaatga
     7441 tgccattgat caattgaaaa acggtggcga aatcagtgat ttactcaatg atattgtaga
     7501 tcatcaaact gatatgatta ctggtcaaaa tggtggttat gttttattag atcctaaaga
     7561 agcgcctagt cgtattttga ttatggacac accagataag aataccgcaa ggaatgtttt
     7621 acaaatcaac aatgctggta ttggtttttc taaaactggc attaatggaa catatgaaac
     7681 ggcatggacg ttagatggcg gattcaatgc ctcgtttatt acggctggtg aaatagtagg
     7741 aattactatt agaggtacta cattaattag tgatggtgct gattatagaa caagtattgc
     7801 taatggcaaa atgacttggt actcaaaaaa agttaacaaa gatattatgg agctagaagc
     7861 acgtgattat gtaagtgctg atgccggtat tgtatcatac accatgaaaa ctggtggtgg
     7921 tttcatgatt agaaatccac agggtaactt ggtttttagt acgtgggata atggtaataa
     7981 cagaccgttt ctatcttttg gtgcgcccaa tttcaggtat agcaatgcta gttatgtaac
     8041 ttctggcgac ggtagttctt taagcattaa tggtagtgcg ggtaactcat gggaatttaa
     8101 ggtagctggt aggactatga aatttactag tgatggtatg ctaacgttac caggttgttt
     8161 ttttggttca tgggaagatg ggaaacttgc taggtttgaa caatcaacgg tacaagtata
     8221 taaagatttt actgttagag gtactaaaaa ctcaactgta ccaacagaac attatggaca
     8281 acgactattg aacgcttatg aaactccaga atattatttc gctgattatg gggaagccgt
     8341 tacaggtgac aatggtaaag ttcgtgttga tattgacccc atgtttgctg aaacagtaaa
     8401 tctaagtcgg tatatgacac atgtgacacc tacagaacta gttttgtgtg ctgttactca
     8461 tgaagatatt gaccatttca tcattgaaac tagtaagcca aacgtattag ttagatggaa
     8521 tttagtggca caccgtctag ggtatgaaga tattagatta aaagaggata cagcatatga
     8581 tagcacagtg cttgaccaaa aacgttttta aaacgaagac aaggaggtat ataaatggct
     8641 agcagtttat ataatttggc tttagatttc agcaaagaat taaactacac caaagctatt
     8701 atggctcgtc aaggtgataa agggattacg gtgacggtta aaccgtttct aaatggcttg
     8761 cagatggata cgagtggcgg aacatttact ttaaaaggaa caacaccatc taaccgttac
     8821 gtagataatg ttgcaactag tgtaactagt gaagaagtca cgttttctct tgatggcaca
     8881 tttatgagtg aagcaggata ttataaacac tgctacgtag aatatagaaa agacaatcaa
     8941 attttaacaa cgcaagatat catttttttc tcactaggag tgtctgacat ttcgcaaggc
     9001 caagccgatg aatatgtttc gcaattagaa gagttgattc gaaagtacaa cgaaactttt
     9061 gatgctttta tggctgaaat caaaggtaga gtggatagct taaatcaaca gattactgat
     9121 ttaactggtc aagctaaaac gctacaagac aagttagatg ctctgaaaga agaaatttct
     9181 aagttaggta acttacaagt gatgtacagt aacagcatcg acttcgggga ctatgattat
     9241 tcggagaacc cgaatttaat gccatatatt acagaacctt gggttggacc tttgttaggt
     9301 aatggacata cagttaaaga tagtgttaaa agggttataa ctcatactaa aactagaaca
     9361 gctaattccg gcgacatatt atcgcttggc ttaggtattc cgtgtacagc ggaagctaat
     9421 aataggtatc ttataaccac tttacgacca tctacgacat acacattaag cgttactatg
     9481 agtgtcggtt cagattggac tggagagacc aatactatag gggttaggct tagatattta
     9541 aatgaacaag gtggtataga actgcccatt aatgcattaa taccagcaaa tgtagaacgc
     9601 gataaaatgg tcactcatac atttactggt ataacaaaag ataatgtaac tagcataaca
     9661 aactgttatg ttgaaatatt ctcacttaat agtgaatata aaggaacggt tagtgtcagc
     9721 tatgacgtta agttaaaagc acactaccct aacttactag atggccctta ctggttaggt
     9781 aaagttcctt taggcgagaa tattgctgac cctacagttg tctttccaca caaaactagt
     9841 gaatatatgg tttatggtag acgcaataca gaaaactata tcgctgacca aacatatacc
     9901 atatcaatga aagcaactaa actaacagtt caatcgtttg ccgtgtatat tgctgctggc
     9961 cgcgttaaag taggagacat gaagcctact gaggggttag ctaatacatg ggagttaact
    10021 tttactgtaa ctaagcaaca tatagatagt ggggtaacta attatctgga aatataccaa
    10081 tacccgtcag ctacaaaagg agctgttcaa attgagtggc tcaaactaga aaaaggcaat
    10141 actcgaaccc cgaatattag tgagtataaa tatcgtggta ctggtatgcg tgattcaaac
    10201 aatccaaaag attatgtttg ggatctagca ccagaatatg tcgaagataa tttggccaca
    10261 gatattaaaa tttctgaaat tactggtaaa gcaaacaatt ataccgatgg gaaagtatcg
    10321 gagattaatt cgcagttgac tgcttcaatt aatgaagtag acaccacagc taaggatgct
    10381 caaacaaaag cgaatgctaa tgcgactgct atagatgaat tagacaataa gatcgatgaa
    10441 cgcattaatg atacagctac taccacatta acagttacaa acgggaatac cggatcagca
    10501 aagctttatc gtgaaggaaa aacagtttct atatattttg tggctttaaa cggaaaaagc
    10561 agtggtggaa atgattcaac gatactaaca attccagaag gctatcggcc accaattagt
    10621 tttgagcaac tggttggctc gatagaccgt tctactttga acagtgctca gttatctatt
    10681 ggtgcagatg gagccattaa atggcgaaga aactcaagtt atggatcgga ttataccttt
    10741 gcaattactt acacgattta gaaaagcgtg aatcgatatg aaggcagcat atagaccaat
    10801 tgaaccttac ggattcgagc aaatcattgt gaatgatgaa gaacatttac cggaagaatg
    10861 cacagaagtc gaaccaccga ttccaaattg gaaaccgaaa ttcaattact gggagggaaa
    10921 taaatgaaaa acatttggaa atatggacgt actggcggag agtacgcagg aaaagtattg
    10981 gacgacatgc ttgtatccgt tccttacaca gatcagccac cgcttgaagg aattcgtgct
    11041 gatggcgaac cgttaacaat cgctgatcaa atgtttgatc ctaaattgaa tcaatggatt
    11101 attttagcga acgcactaga tcacaacgat ttaaacaatc tcaaagcaat gtatgagtcg
    11161 ttagaaaatg agaacggcga tttaaaacag atcaatgcca aactcatgct aagcgatgta
    11221 gcaattaaac aggaaaatac tgcattgaaa gaaaaagcgg atagtttagc acaaatcaat
    11281 tcaaaaatga tgcttgcttc gttacaaaat agcaaagaca tttcagaaat taaagagcaa
    11341 ctaaatccag cttcaaaggg aggtgagtag tatgtttagt tttagcgatg tgaaaatgat
    11401 gtatgattgg ggctgtttca ctaacgaaca agtaatggtt ttcgttccgt tgtgcattac
    11461 tgaagaaaaa gcagataaaa tcattagcaa agaagagagc gcatcttaat tgatgtgctt
    11521 tttattttga ttcaaggagt tgtcacatga ttaatttagg ggaatgggga gcgatagcag
    11581 gatcaataac cgctatcgtt tctttgattt tattagtaat aaaaccaatt actgcatctt
    11641 tctcgaagat tactgagact ctttcaaaag taagtcacaa tttagatttg ctgactaaag
    11701 atttagaatc gagcaaatca gatcgattga tgattcatga agaactaaag aaacacgatg
    11761 aaagattaga tacacatgca gaaaaattgg tagaacacac gcaacaaatt aaaactttat
    11821 ttagggagag aagaaaatga ataataaaac gttcgaagta ctaaaatggt tcgcactggt
    11881 aattattccc gcactagcta ctttcgtggg gttagttggt aaagcgctca attggcagta
    11941 cacagatatc tgtgttgtca tcattactgg ttttggcgcg tttttaggga gtgtgttggg
    12001 tgtatcaaat cgaacctaca aaatgttctc ggctgaaagc gaagaaggag gaaacaaatg
    12061 aaaaagaaaa ttactattac tgcgatgagc ctgttaacgg ctcttttttt attacccatt
    12121 aatacgtttg cttatactat taatgacgag tataatttag cgccgaatca aggagactcc
    12181 agattagcaa ttcctaacaa aattattttg cacgaaactg gaatagatgc accagcaaga
    12241 aacgtagccg ccaacatgaa aaataattat aacggaagca attcttatac tacagatgtt
    12301 attggtgacg gtgggattgt ttaccgtgtg ggtgagcaag gatatgtttc gtggggagct
    12361 ggtaacgcta atccttatgc gcctgtacag attgaattac agcgcacata tgataaagca
    12421 ttgtttgaaa aaaactatcg agcttatatt gaatatacaa gagatagtgc aaaaaaatat
    12481 ggaattccat tgactcttga tcaaggaact tctttattta caaaaggaat catttctcat
    12541 ttgtgggtga caaattatgt ttgggggaac cacacagatc catatggtta cttatcgcaa
    12601 atgggagtta gcaaagaaaa gcttgcttat gatttagctc atggatttac cgatgaaaat
    12661 ccaacaactt ctgaaaacaa gcctgtcatt gatccaacac gagctggtgc agctaatcct
    12721 acgctgacag atggaacaaa tcacgcccac attgatcagt ttggggaaat cgaaaacgca
    12781 aacttgcatg tggctggatg gcacattgct aactataaat acgagtatat tttcattatg
    12841 gactacaata ctgggaaaga attagctcga gtaagagctg atggaattta tagaccagat
    12901 gtaaaccaag cttataatac ttctggaaat gttggttatc atgtatcttt caatatgcgt
    12961 aattttccta gtaagaaagt ctatgtaatg atgcgggcaa cgaatgatcc agagggaaac
    13021 actaaaggcg gtgcgcaaga tttccatgac aaacgttggt atttaaatat tcctaaacga
    13081 taaaaatagc tcctcgttga ggagcagtac ataactatat tgacaactat aaaaattatt
    13141 cgataaaata gtgatgttat cgcatatctt cactatcacc cataaatagt cacactccaa
    13201 gctatgcgat aacaggtttg ttgccacaca ttctactggt tgattgttta tggctttatg
    13261 tggcaacaac cagtaccctt agctcagttg gtcagagcag acggctcata accgtccggt
    13321 cgtaggttcg agtcctacag ggtacattaa cgtagccatt tgaatcgttc tgtgttagaa
    13381 tttttttgaa gagtattata caagctaaag cttttcttca ttgccactca aatgagtggc
    13441 ttttttatgt atccttttat ggattaatga aaggatgttt cacatagtta tacttctgta
    13501 tatttgaaaa gttttacttt gatttttaaa tagaaagaca tttgggttaa attgtgagat
    13561 aataataaag aagagtttaa agcgcacccc aaaccacttc cccataagtg tgttacgctt
    13621 taaactcttt tatatttgaa gccattaaaa agcataccat atttttgaaa aaaagtgaga
    13681 aaaaaggctt acaattggag tggtagttaa ttagtgactt atttttgatt ttatagcact
    13741 gatactataa aatatagata tcatcatatt acacaatctt aatactaact taaaaaatat
    13801 ctcctttcac aagtatggtg ataaaattcg ttccgggcta cctttttagg tagcctactt
    13861 taatctttat acctttctgg atcaacgaaa gtatacttta tatagtcata acgccgatga
    13921 tcgctacgtg cgtccggcac gtcagtc
//
LOCUS       DAZULR010000058        13895 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.059, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000058 DAZULR010000000
VERSION     DAZULR010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13895
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.059"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            145..1596
                     /locus_tag="ACG8ZV_002260"
     CDS             145..1596
                     /locus_tag="ACG8ZV_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFS4997543.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSTESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
     gene            1945..2577
                     /locus_tag="ACG8ZV_002261"
     CDS             1945..2577
                     /locus_tag="ACG8ZV_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HFS4997544.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLTGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            3165..4604
                     /locus_tag="ACG8ZV_002262"
     CDS             3165..4604
                     /locus_tag="ACG8ZV_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4997545.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            4899..5117
                     /locus_tag="ACG8ZV_002263"
                     /pseudo
     CDS             4899..5117
                     /locus_tag="ACG8ZV_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
     gene            5366..5581
                     /locus_tag="ACG8ZV_002264"
     CDS             5366..5581
                     /locus_tag="ACG8ZV_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997546.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(5798..6054)
                     /locus_tag="ACG8ZV_002265"
                     /pseudo
     CDS             complement(5798..6054)
                     /locus_tag="ACG8ZV_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(6241..7152)
                     /locus_tag="ACG8ZV_002266"
     CDS             complement(6241..7152)
                     /locus_tag="ACG8ZV_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFS4997547.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(7171..8175)
                     /locus_tag="ACG8ZV_002267"
     CDS             complement(7171..8175)
                     /locus_tag="ACG8ZV_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HFS4997548.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(8172..10295)
                     /locus_tag="ACG8ZV_002268"
     CDS             complement(8172..10295)
                     /locus_tag="ACG8ZV_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HFS4997549.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(10300..12747)
                     /locus_tag="ACG8ZV_002269"
     CDS             complement(10300..12747)
                     /locus_tag="ACG8ZV_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFS4997550.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKDSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            complement(12734..13123)
                     /locus_tag="ACG8ZV_002270"
     CDS             complement(12734..13123)
                     /locus_tag="ACG8ZV_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFS4997551.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(13183..13686)
                     /locus_tag="ACG8ZV_002271"
     CDS             complement(13183..13686)
                     /locus_tag="ACG8ZV_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HFS4997552.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            complement(13699..>13895)
                     /locus_tag="ACG8ZV_002272"
     CDS             complement(13699..>13895)
                     /locus_tag="ACG8ZV_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997553.1"
                     /translation="WFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFLVIALIAVGLV
                     FNASGVKDVLLSLFNRIVGA"
BASE COUNT         4300 a         2728 c         2530 g         4337 t
ORIGIN      
        1 aaggcagtaa caggattaaa cattgaaaca taatcgttac taaatgaaat caagaaatat
       61 actgtattac tcaattcatt gaaaatattt atcataattt ttaatagaaa acactattaa
      121 agagaaaaaa gagaggtaaa tcaaatgaaa aaatctttaa aacttgcatc agcagttata
      181 ttaatgtccc aactccttat agcaacacct ttccatgtgt tggcaagcga aaattcaaca
      241 tacaaaattg caaaagaaag aaccgagacg actgaaatga gtaattccga tgtaacagca
      301 gagagtagtg aacttttgac aacttcatca agtgaaagta gtacgacttc aaatgccgag
      361 tcttcaacaa cttcatcaag tgaaagtagt acgacttcaa atgccgagtc ttcaacaact
      421 tcatcaagtg aaagtagtac gacttcaaat gccgagtctt caacaacttc gtcaagtgaa
      481 agtagtacga tttcaagtac cgaatcttca acaacttcaa gtagtacaag tgaaataact
      541 tcttcgaaag tgacaaaacc aaaccatata gaatcttcaa aaaaggaagc gccaaaaacg
      601 gaaggacaaa caaaaacttt ttcgacacca cagcaaatag aatcaacaga atctttccaa
      661 tcacaaccaa tactatctgg taatgaagaa attcattttg acaaaaatga atctgtagaa
      721 aattttatta tgaaaattgg tgagtctgcg agaaaaattg gtcagaaata tgatttatat
      781 gcttctgtta tgattgcaca agcgatctta gaatctgcca gtggtcaaag ccagttagct
      841 caggcaccga attacaattt atttgggata aaaggaactt ataatggaaa ctttgtcatt
      901 atggtaacaa acgaagattt gggtaatgga acgctttata cgacccaatc aaaatttaga
      961 gtgtatgaaa actatgagga aagctttgaa gattatgcca aattattaac taagggaatt
     1021 agtggaaata aagattttta tgcaggagca ttaaaagcta atagtaaaac atatcgagaa
     1081 gcaactaaat tccttacagg acggtatgca acagatacac aatactattt gaagctaaat
     1141 gaattaatta aaacctacga tttaaccaac tatgataaag aagttaaagg tccacaaatg
     1201 agtaagactg gataccaagt gcctattcat aattattcaa taaccagttt gtttggaaat
     1261 cgtggaaatg aatttcaccg aggacttgat atggcagcta cacagggtga gccgattcat
     1321 gcagttaaag ctggtaaggt tgttaaagca gagtttcact actcttgggg aaattacgtg
     1381 gtgatacaac acgaagatgg atcaaccgcg ttatatgctc accagcaaca atacctagta
     1441 aaaactggag ataatgtttt gcaaggacaa ataattggct atgtaggaag tactgggaat
     1501 agtactggcc cacaccttca tttggaaatt tgcaaagata gtagtctttc tcagagcatg
     1561 ttagttgatc cgaaaacctt attattcgga gactaaaaaa ggtaatcaat ctgacaaagt
     1621 aacaagaaaa tggttggatt cttagacctt tgatcaggat attgagactg gaattgatat
     1681 ctcgattacg atgggtttga caaataaaac aagtccatta tcgaatatcg agtgtattat
     1741 tgccgtcttt atgctcatat tttgagcagg tttcactaga tgaaaacaat ttatctatct
     1801 tgaggatttc gtgtacgtat cgttcagtct tgtattgtaa attagtcata aaatcagact
     1861 aagaaaaatt ggaaatattt ttttctgatt tattaaaagt taattgaaat tatatggtac
     1921 ttctttcttg ggagggtagg tgcagtgaag gaaagatatg gtcaccttac tgttgttgag
     1981 gagattactc ataatggata taaaaaatat cgttgcctat gtgactgtgg gaatgaaacg
     2041 attgtatatc gatcaaactt actaacaggt agaaccaaaa gttgtggatg tggaaattat
     2101 aaaaataggc ataaatataa aaatttgaca aataaaactt ttggtaagtt agttgcaatc
     2161 aagccaacta aactgcgaag tgaaggaact gttgtttggg aatgtcaatg tctgtgtggg
     2221 agaaaaaagt tagtatcggc aaagcgactt ctaaaaggtg atgtaaaaag ctgtggatgt
     2281 ttgaaatcaa aaaagcatca cattgaaaat aaaaaattcg gattacttac tgcaaagtat
     2341 cctttggaca ataactgttc atggaaaaca aaatgggttt gtcattgtga gtgtggcagt
     2401 atgtgtgaga taagttatag taacttattt tttggacata ctcaaagttg tggatgttta
     2461 aaaaggcaag aaacaaggac atgtgttgaa gggacagtaa tagagtgtct aacgtcaaaa
     2521 ttaccgaaaa ataatacaag tggtgttaag ggagtttatc gttctaaaga gaaatagatt
     2581 gcgtatataa ctttaaaaaa aaagaggtac tatttaggat cgtatgattc tattaagagt
     2641 gcagctcaag ctagaaaaga tgctgaaaat aaattgtttc aacctttgat tgacaaatat
     2701 cgaggtaatc attaattatt gtggataata attaacagtg atatataaac atctataata
     2761 tattattcat actattgata tttagtataa tcctatggaa ttgaatatca tagcaatgta
     2821 tttgaaaagc aaattggaaa acaaataggt gcaacaccat aaatatgaaa aaattgggaa
     2881 aaagtagaat ggaaatttgc ttacgtctca cgagatagct cacactatta atctgaagaa
     2941 caatgaagtc gacttttaga aattgctaga agaaagtaaa gcgaattatc actagttact
     3001 atagagtaag ttcaaataaa gcatctccaa cttacatggt tacatgagga tatcaaatcg
     3061 aaattactca agcttcctat ggctagagtc gcgagaagtt gttgggcagt agacataggt
     3121 tatattgttc ttagctacac gatcattaga aaggaaatcc tattatgtat agttatcaag
     3181 aagatgcaaa agtccaaaaa aatcgctggt ggattttgat tgctatatct atgtttacct
     3241 tcatgtccac attggatggc agtattgtca atattgcact acctaccatc tcagatgata
     3301 tgggcatacc aatgaatcaa gcggaatggg tagtgtccgt ttatctgatg attgtctgtt
     3361 cttgtttgtt gctgtttggt aaaattggcg atagccgtgg gaaaatcaaa gtatttcgga
     3421 ttggtacgct gatctttgtc ttgggatcgc tgttgtgtgg gttcaatcat tcgctaggta
     3481 ttttattgtt cgcacgggtg gtacaagcca ttggtgctag tatgactatg gctacaaatg
     3541 ccggaatcat cacggaagtc tttcccatac atgaacgtgg tcgggcattg ggagcaatag
     3601 gtgcgtttgt ttcattaggc tcgattgctg gaccaggtct tggcggcttg attttgtccc
     3661 aattttcttg ggcgtacatt ttttggatca atgtaccggt gggaatcgta acgatgttga
     3721 ttgctgaaaa attcttacca aaagatatca ccatgagcgg ccatacaatc gatggagggg
     3781 gctttgctgc cattgcggct acgattatca gcttttttgg agcaatcttt ttggggcaag
     3841 aaagtggctt tttccatcca gtcccccttg tactgttcgt aatttcagtg attgcctttg
     3901 tcagcttttt aaaagttgaa aagaaagcag cctctccatt gatttctttc ggtattttta
     3961 agaacaagat ttttaccatg agcttgatta cagccttgtt gattttttct tccaacttct
     4021 ttgtcaatgt agtgattcct ttttatctgc aaaatgctcg cgggttgagt cctagctatg
     4081 ctgggctgtt gatgatggtc tttcctttga tgatggtcgt cggggcgcct ttaagcggct
     4141 acctgaccga ccgggttggc ccggagattt tggtattagt aggcttgggc ttattgtcgg
     4201 taacccaggt catgtatatg tttttgtcag tggactctcc tttgtggcta tacattgtcg
     4261 ctactgccat catgggtgcc ggcaatgcct tgttccagtc ccccaataat acgatggtta
     4321 tgagctcggt cactatcgaa aacttgggac tggcaggctc gatgaattcc tttgcccgaa
     4381 atttggggat ggtcagcggg atttcgcttt ctacgacggt cttatatcaa gcgatgtctg
     4441 ctaagatggg ccagcaagta actaactata tcgcaaatcg gccggatgtc tttttatatg
     4501 gaatgaagat taccttttta ggcagctttg ttttgtgttt tgttgccttt ttcctgacta
     4561 tctggcgtat caaaaaacaa ggaggtattc agaaaaatgt ctgaaaaaac cactgttgaa
     4621 gaatttttgg aggcctgcgt atgggtgagt gggatttcca tggatgatgg aagatgaagt
     4681 gaacttctaa aagccgaaaa actcaagtat tatcttcaaa atactagtgc tcaatgagat
     4741 gcttgatttg atcacaagaa gactgcgaaa gccgctggca accgcaagct aggtatccca
     4801 ccgatggact acgttttaga ggctactggt tatgaatacg gagccaacgc tctcatctgc
     4861 ataagaatac atcacccaga ttatgtaaag attttcgata cttctgtcaa aaaatcatta
     4921 agatagataa atgatttccg tctagtcaaa ttggttcaga atgtagacac acagatggta
     4981 agaagtcact cacaattcga gaatggactt gtcctatttg ccgtatacat cataatcgaa
     5041 acgtcaacga tagtatcaat attttgacca agggctatga atacaagcat tgccttagaa
     5101 aacatcaaga accttaggaa caacggggat agcttggtta ataagagata ccgctgttta
     5161 ggcttgcaag tatactcttt tatcaagaat tccgtggctt tagtcatgag aggcttaata
     5221 ctatgaaaat tttctttagc atttttgatt taggttcctt ttctaattat aataagatga
     5281 ccactacagt aacctactga aatatataaa cagccactgt agtaccattt tcaaagtagt
     5341 ctatgagagg agaatcttca ttcttatgaa cgctggaatt gcggatatga atttaataaa
     5401 aaaaaccctt aatgatttta cttccaattc aatatcaaaa ggtactggta tcaatttaag
     5461 cacaataaaa aagctgaaaa gtggtgaaag atcagtggaa aagctgaatc ttttagatgc
     5521 tataaaaata acggaatttg ctatgaaaaa tggaaaagct gagattgaaa tatggagata
     5581 attatcgtct agtgaattac ttgccactta gctgaattta acgatccttg gtgcttgaag
     5641 ggggagattc ttgggaatag agcatacttg caagcctatg tctttactaa caacgatatc
     5701 tcttattaac caagctatcc ccgtagttct aaggctttta cttttatcta agcaataatc
     5761 gtattcaaag gaaatttttg acccttagaa agtctcattt tatcagacgt gagcttaggc
     5821 attgctgaat tttgttaatt cggttttagg ttgtgctttg agcataatat gaaagtattc
     5881 tttatcacga tttcattcat ctaaggtaat gtgatgtgat tctgaaattc tttcaaaggc
     5941 agtttttgca taagctgaca ttacatcatc aatgacatgt ttacaatgtt tcactactaa
     6001 aataaggggg taaccaagaa gaaaaactga atgattattt gtatctaatt ccatggtata
     6061 tcaaccattt cctatataga ctgattatga catggattaa aataaaaagg cactatgtct
     6121 taattgtcgg ttttcgagtt accgaatggc attcatcacc cacctataga ggatgggcga
     6181 cttctgcctg aaataagtta cactacttat aacttctaat aaaattagat tgagtcatta
     6241 ttatttaaca tcaacgattt tccagtttcc atttttttgt aatactaatt tgtactgaaa
     6301 gtagctagtg gtttttgata cattatcaag gtattttatc tttgtactca ctagaaaatt
     6361 ttttccgttt tgtagataaa ctggattctc taactccgaa aactttaagt caatattgat
     6421 tggtcgcatc gcaccatttt caacataata ctccaattct ttttcagaag ctgatggata
     6481 aagtttaaaa aatgtttcta aaaaatcggt gatttcttcc gttgttttgg catcaatttc
     6541 tgaatcgttt tctacttgtt ttgcttcata ttttgccttg tctggctttc caatcattgt
     6601 tggcaaacta gttactaaat gattcctgtt ttcatcttca aagattgtca ctcgatatgc
     6661 agaagaaatt gattgcgtct tttttccctc tgtaatatgt tgctccacta aaaatgaaac
     6721 gacaaattct tccgagtgtt tttcaacatc tagaattttt acagattgaa cttcggaact
     6781 cgtgggaata tctgctcgaa ccatatcttg gattaaagcg agaccgtttt ctgtaaggta
     6841 ctgttcgaga ttactcattc tcttttcaat tgcttctttg ttatttttcc atgaaaaata
     6901 ttctttcgca aaatcctctg taaaactttc aacgccagaa gtattcacta ccttctcttt
     6961 tataaccact ttttcatgag ttgtatgttg atcaatggcg gtgaaatttt tataaacgcc
     7021 aaaagcaaga ctacaagaca ataaaagcca aagggcaagc accatttttc gatgcttacc
     7081 cacggataca actcgttctt ttttcttttt tgggctcttt tccttttgat tccgttcaat
     7141 ttttatcttc attctttttc ctcttttctc ttatttgtat cggccagctc cgataagatg
     7201 ctgccgccaa tagttttccg ttagattcgt ccaccccact ggatctcctg catgaaacat
     7261 gcgattctcc cctgcgtaaa tgcccacatg ggtcacataa gtaccggcat cataggttga
     7321 atgaaagaaa actaaatcac ctggtttggc atcttttaga tcaatatgag tcatggcatc
     7381 atattgatcc tgagccaccc gaggaagttt caggtcaact ttggcataac accattgggt
     7441 caagccacta caatcaaacc ccgtttctgg acttgagcca ccaaacacat aggccgttcc
     7501 ttcatactta aatgcctcat caaaaatttc ttggactatt ttgtcatcaa actgagttgt
     7561 agttaggtat tgcttcacta ataaacagta aaacatattg ccataattat accgccaccc
     7621 accattttcc ttaatcgcga ttgggttggg gtaatcgact ttttgaccac ctgatttttc
     7681 ctttgaaaaa gattcagcta aagcaaaact atgcttcttc ccgtttttcc cgacatgatc
     7741 tagatacccg ccaccatagt tataggcctg aataatacta tcttgatcac accctagttc
     7801 tttggaacgc ttaaccaaag acgcaaaata gagacagcct tgtttgatgg atgcctcggt
     7861 acttaatgaa ttaggtggta atccggctga ctcagaactt tgcataacgt cttccattgt
     7921 gccaccagat tccacttgaa taatcgccaa aagaattgga atatactctg ttatatccga
     7981 ttctttggca tacttttcca ccattgcacg gtgtttcaat acttcttctg agacactagt
     8041 tccgccagga gaagtgccag aactaccatt tccctcactg tcttcaccaa acaacaaacc
     8101 cacacacatc aaaataccca taaaagagat ggtcagaaaa gttaatgaaa taacacccac
     8161 tttcttcaag ttcatttttt ctcacctgac cttgattttg gacgatggtt cattcttttt
     8221 tgtacttttt gattggtctg ctttggcaga gtggacctct gtttcacttg ttggaaagaa
     8281 tttttcttac ttgctgattg gcttttccct tttgaaatga tttcttgact agttagtttt
     8341 cgtttgattt cgggattcag atttgctctc acaatccgct ttggtgcttc ttttttcagc
     8401 atcatatctt tctgaggttg agctgcttta tctattggaa tattcgccct tctttttccc
     8461 tgacgatttg ttgcttcact cagtatcttg cgtttttcgt ccattttcgc atttcttcgt
     8521 tgtcgttgtt tttctcgcaa atccactcga tccgcttttt cttggaacag tccgcgcttg
     8581 aattcttctg gtgctttttt cgacttttcg attcctttat gtagattgta tttcaaattc
     8641 gttggcgtat tccttacctg atcctttact tgtttagtct tatctttcac caaagcttgg
     8701 gtatccaaaa ctttgccgat ttttctccca gccaaattca ttcgggattg tttcttatta
     8761 tttgaaactg gattctcctt agttaagtca gatagtattt cgtgatcgtt cggtaatcgt
     8821 gaattctttc gtagagaaga accggatggc ttaaatttgg attttgattg ttcctttgcc
     8881 aacttatttc cgactgctgc accaccacca aaagccaaag ctcgtcccac atttcgattg
     8941 agttgccgca attttcgatt cattaacatt tgcggttttc gcatgacgcg tcttcccatt
     9001 gactggctat cattactctg gaggttgaac atactcataa tgtcgcccaa tttgaaatag
     9061 ataccggcaa aggtcacaat ttgcagaaaa gcaaccatga aaaatggata ggttgccgaa
     9121 atattgaaaa acatcgtgga gatgctaaat gcagtcgtaa tcaccaaagt aacacccgct
     9181 cgcatcataa tcgtattgaa taaacgaata atcgccttct ttcctaaact ttcataagtc
     9241 ggcaacatgg acaataagaa actaattggc agaaacatcg caaagataat gaagagaatt
     9301 tgcgagaaca acataatccc tgttagaaga aaaacaaaga aggaaatgcc aatattgaac
     9361 aataccaaaa agaccacggt ccctaaacgg ttcatggtct tggtaatact gagattcgca
     9421 ttgtcattgt cttcaatctc tgccttgacc gcttcttccc gatctttgcc tttgttttca
     9481 tctggactca cagatagaat cttgttgacc cggtcttcac caatttcttc tatgttggaa
     9541 tcatcaaatt gcagtagtaa ccaaggttgt tggacttgaa tcgaaaacaa actatcccga
     9601 atcaaatcca cactatcttt tccttggctt tctgaattgg gtacaacgat ctcggttcca
     9661 agggtaaggg ccgcttcact aacatctgag ctaaagtcat tgatttttgt gatataggta
     9721 ggcgcataag caatgaacga acccgatagt agaaaaatca tcacaaaatt aatcacggct
     9781 cgaactgctt tcgtggtttc tcgttttaat aatccggtat acgccacata cacccccaga
     9841 gctaaaatca tcaataatag aaacccaaaa taaaatccgg aggtctggag tccattttca
     9901 gtaataccag ccaatgtttg gatattcttt ccaatacttt cagccgtatc cgaaatgaaa
     9961 tctaatttgt aagcctcttg aaccacataa cccgtggcgt tcgacaaata caaactcacc
    10021 gtccaaatga aattagtaat ggcataaaga ccatacatca cgcttttccc taagccatca
    10081 ccccaattcc aaggcaacca atcccaagag ctatccacaa agaaatctag ttgatagttg
    10141 ttcagtgaat atttggaata tagatttcct gcttcaactg tatcatcaac tagccctgtc
    10201 gcctcggcta ccgtaccaac taaactcaat agaactatca gagtgagtat gctaataaaa
    10261 acgattccca caatccgaaa aagtttcttt ttcatcccct cactccattc tctcttgaac
    10321 aggtggacgg gtatcaaagg catggaagag ttcttcaaag actggatgta cctgaaccac
    10381 gcctacccga ccatacaaat cctgcatcaa gcattggcca ttttccaaat ctcgtaggcg
    10441 tttttgattg ctttcatctt ctcgatccaa gccaaagaat tccaaggttt tcttgatttc
    10501 atgaatatcg gtactgcgaa acgcaaactt caacccgata ttattcttca agcgttcatc
    10561 cagtaaatca tcactatttt gcgtgacaaa gtaaaccccg gcattcatag cccgcccagc
    10621 acgaacgagc ttattcgata atgttttccc ttgcgctact tgaagaaaac tccacgcctc
    10681 atctaagtct acaattttga agatttctcg attactatgg ataaagtcca aggcaaaagt
    10741 ggaaatgacg attagcatgg aaacactaag caattccatg gtggtatatt cttcaaaagt
    10801 ggtttctgca tctggtaaaa ccaaatccgc tacttgaatg atatttaact gcctatctaa
    10861 actaatcgac tgggtaatcg aaccatctga gaaaagcaaa tgggcaaaat cataatcggt
    10921 aaaggactcg atgtgatccg cgatattttc cgcaactggt gagccttctt ttcgaagctc
    10981 attaattact tgtaataatc cccgttgatt gctttgggta accgtccgaa tggccttacg
    11041 caacactgga aacttctccc catctcgact agaaattcct gttaaaaagg tcagaatatc
    11101 aattgctaga ctttcagaat ccttcttttt ctccataatc acataaggat caagtaatcc
    11161 ttgatttttt ggcttactag ttaagttgag aatattgatt tcatccgcaa tttctggcaa
    11221 ggtttctttc cagccacccc gttccccttt tggatcgaca atcacagctt gtccaccaaa
    11281 aaggacggcg taataaacta agagattgtt actaaaggac tttccgccac cgagtgaacc
    11341 gaggaatgcc gctgctagcg cattggtaac tgaatccttg accccttgtg aggccaatgc
    11401 cggtttcagg taaacattgc gccccgtatc tacgttataa ccaaagtaaa tgccttccaa
    11461 ctcccctaac atctgagtgg cgccaaaacc aagtccggcg agaaaatcag acgtaacata
    11521 ctggatataa tcattcatgt atcgcttact agaaggtaag aattcttcat gtagccccat
    11581 catatcgcca aaaggccgga ctagttttac attggtatca tcataaaaat ctagcacttc
    11641 atcacaccgg cgctttagtt catctactga ttcggcactt actcgaacca catagctcag
    11701 tttgtacatg gattctttgg actgatccaa ggtagtttcc aattcatcta cggaatccaa
    11761 tgcatctaag acattggaat ttgtttcatt gtcagattga taggcatggt tgtccaagtc
    11821 ttttaattcc tttttcttat tgcgaacggt agcaagtgcc tttttgttcg tcacaatctc
    11881 cacattcata ctagtgtcaa ttgggaatgt aaattgttgt tgctggtaat agaaaagttc
    11941 tgaggaggga aactccattt cccccacaat tgtattaatt gttaagtacg ctacatatga
    12001 ttcatgattc tcatgttcca tgcataagta ccggggcttt tcttcaatca aacaacgact
    12061 gggacgtaat aagtcgtaac gtttcaccaa agtttccgac ttcagctttt tctttggtag
    12121 ctgaaattca tattcttcaa atggtgtacc cttttcgcca tagatatgtt caatcaaata
    12181 catcagatca ctcggtgtga ctcgtctgac tttaaatctt cgagccaatt tactttccat
    12241 tagtttttca agcttggtat atcggcgaat ttcttcattg gataaggaaa caaaatcgcc
    12301 catcaaatga tgattcactc catagacaaa ttcttgaaag ccggagaaga aagatttctt
    12361 gagattcttt agattgacct cttcatctgt cgcaatcagt ttgaagccaa taaaaaagcg
    12421 ataatcaatc tgactatcgc caatcatgga tactaatgcc tctgtctgta aatcaattcg
    12481 ttgtttcgct acttctgtta atcgcccggt aatttccttt tttgatcgtt cttgcgtggc
    12541 acgaatacta ctttctgtgg caatttgtaa ggcatgaatc ttgccttcac gattttgcgc
    12601 aatcaattga cgaaagttat cgtggacttg atatttctgt tcaggtgaca aaaaggagta
    12661 attgtaaggt attaactcat agtaggcaaa acattctccc tcttgattaa agacaagatt
    12721 attttcaata tacttaatcg ggtacatagt tcacactcct taccagagta atgggttcgt
    12781 cccatcgttt cttctgttct ttgactttct ttcctgcgaa agtgacctta aatcgtaagt
    12841 gatagctaat aaaagatcgt aaaaatccca atggtttctt accgtcaaac gttttttgcg
    12901 acatgaacca agtaactgcc accggtatac ctaagtattt taaaaaggcc ccctctatca
    12961 tagatagtgg aggcacatgg gcaaatacga tgacaaacag caaggataaa acaaaccaag
    13021 ccatctggtt aaaagtcaca ggaaaaggca gttgaaagtc attaattgca taaatgacct
    13081 tttcaactgc ccaaatactg gtgtagcttt ttattttctt catcaaatca ttcctttaaa
    13141 aagaaggata gtttagaaat caactaccct tcaataattt tgttaatatg gatactcaaa
    13201 aacacctcga ctcgttacca aataattgcc tccaatctcc aagtctctac cacacgcatc
    13261 aaaatcaata tacgtcttca agtgttctgg tacttctcca aaatcaccag cttctacaat
    13321 caagaaatat gctacatcac tcatatcatc gcaatctgga taatagataa tatcatccac
    13381 atgctctacc atctcctcaa aagaattgaa gaaagcatgt tgaatctcag aagcaacttc
    13441 accaactggc gttccttcaa gttcctccgc taagccacac aaccgattaa tttcctcaat
    13501 tggcgtatac tcatcaatct caaagggaag ttcataatca tgaattgcat attcctcgta
    13561 ttcgtcattt aacccaattc gttctttcac ttcatcaaaa tcgacaggtg gggtaaacca
    13621 cgcccccacc aattcacctt cgttatattt cccgaggttc gcaatataaa cacgcatctg
    13681 ttccatcgtg cttccccctt acgcaccgac aattcggtta aacaaactga gtaagacatc
    13741 cttcacccca gaagcattaa agaccaatcc gaccgcaatc aaagcaatca ccaaaaagcc
    13801 aatcagtttg gaaaactccc gcttaaatcc taaaaacaaa ccaatgacca caattgccag
    13861 taagactaag gattgggcat tggttaaaaa ccatt
//
LOCUS       DAZULR010000059        13818 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.060, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000059 DAZULR010000000
VERSION     DAZULR010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13818
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.060"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(163..2160)
                     /gene="tkt"
                     /locus_tag="ACG8ZV_002273"
     CDS             complement(163..2160)
                     /gene="tkt"
                     /locus_tag="ACG8ZV_002273"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HFS4997554.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2262..2513)
                     /locus_tag="ACG8ZV_002274"
     CDS             complement(2262..2513)
                     /locus_tag="ACG8ZV_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HFS4997555.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2660..3283
                     /gene="lexA"
                     /locus_tag="ACG8ZV_002275"
     CDS             2660..3283
                     /gene="lexA"
                     /locus_tag="ACG8ZV_002275"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HFS4997556.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3463..3681
                     /locus_tag="ACG8ZV_002276"
     CDS             3463..3681
                     /locus_tag="ACG8ZV_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997557.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3970..4482)
                     /locus_tag="ACG8ZV_002277"
     CDS             complement(3970..4482)
                     /locus_tag="ACG8ZV_002277"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HFS4997558.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4496..6793)
                     /gene="recJ"
                     /locus_tag="ACG8ZV_002278"
     CDS             complement(4496..6793)
                     /gene="recJ"
                     /locus_tag="ACG8ZV_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HFS4997559.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6935..7378)
                     /locus_tag="ACG8ZV_002279"
     CDS             complement(6935..7378)
                     /locus_tag="ACG8ZV_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapA
                     domain-containing protein"
                     /protein_id="HFS4997560.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7379..8167)
                     /locus_tag="ACG8ZV_002280"
     CDS             complement(7379..8167)
                     /locus_tag="ACG8ZV_002280"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HFS4997561.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8164..9105)
                     /gene="rnz"
                     /locus_tag="ACG8ZV_002281"
     CDS             complement(8164..9105)
                     /gene="rnz"
                     /locus_tag="ACG8ZV_002281"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HFS4997562.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9282..9869)
                     /locus_tag="ACG8ZV_002282"
     CDS             complement(9282..9869)
                     /locus_tag="ACG8ZV_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HFS4997563.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10090..11403)
                     /gene="obgE"
                     /locus_tag="ACG8ZV_002283"
     CDS             complement(10090..11403)
                     /gene="obgE"
                     /locus_tag="ACG8ZV_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HFS4997564.1"
                     /translation="MSMFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGG
                     DVILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAET
                     GALLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVL
                     ADVGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLE
                     RPQIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNAT
                     ADLLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTN
                     FDHDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11700..12710
                     /gene="gap"
                     /locus_tag="ACG8ZV_002284"
     CDS             11700..12710
                     /gene="gap"
                     /locus_tag="ACG8ZV_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFS4997565.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12795..13730)
                     /locus_tag="ACG8ZV_002285"
     CDS             complement(12795..13730)
                     /locus_tag="ACG8ZV_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFS4997566.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGCFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT         3811 a         3096 c         2436 g         4475 t
ORIGIN      
        1 tctcaagaaa cacaaactaa tccgaagaat tctttgtttt gtcatttaaa tgtaacatag
       61 ccgaaaacga aaagtaatat tgatttattc ttctaacaca taaagaacag ctgtctccaa
      121 cttgcagaca gctgttctta tcagtcaaac aattgcttgg atctatgata gttgattgta
      181 cgtattcacg acattttcta ctgtaaatcc aaattcttct aaaattttag tgccaggggc
      241 agatgcaccg aaatgatcga ttgtaatcgt tgcgccctct gttcctacgt agcgttccca
      301 tccaaatgat gcagcagctt cgatagccac acgtttcttc actgatttag gaagtacact
      361 ttctttatat tcagaagatt gtttttcaaa gaggtcaaag cttggcatag aaacaacaga
      421 aacatctttg cctttttcag ccaattcttt ttgagctttc acagccaaat caacttcaga
      481 acctgttgca atcaaaatac cttctggtgt ttctccttgt gatggagaaa gaacatacgc
      541 gccttttttc accatttcat ctgctacttc ttttgtagaa ggcaatactg gaaggttttg
      601 acgactcaat acaaggatag taggcgcatc tgttgtctcc atcgctactt tccaagcagc
      661 acgtgtttca tttccgtctg ccggacgaat cacttgaaca ccaggcatgc agcgaacaga
      721 tgctagttgt tcaatcggtt cgtgcgttgg tccgtcttct ccgacagcaa ccgagtcatg
      781 tgttaagacg taaacaacag gagtatgttg gattgctgct aaacgaactg ctggtcttag
      841 ataatcgaca aagacaaaga atgttccacc gtagatacga gttccgccat gaagttggat
      901 accattcata gccgaagcca ttgcaaattc gcggacaccg aaccagatgt tgcgtccttc
      961 ataatgttca ggagtgaaat ctttatctgc agccaccatt gtattattgg aacctgacaa
     1021 gtccgctgaa ccaccccaga agcttggtat agctttcgat aattcttgga tgacttcttt
     1081 acttgaaaca cggcttgctt gactgcttcc aacttcataa gttggcaatt ctgcatccca
     1141 gttttctggt agtttgccat caaaagcatc ttcaaattgt tgtgctaatt caggataagc
     1201 ttttttataa ttggcaaaca tttcattcca tgcatcttca gctttttgtc cttcttctat
     1261 catcgtttga tggaagcggg cagctacttc ttctggaaca gtgaaatctg gatactccca
     1321 accataaact tctttagcca tcttgatgcc atcttcacca agaggagcac catgaacagc
     1381 agatgttcct tctttaggag caccatagcc gatgactgtt tttacttcga tcaatgttgg
     1441 tttgtctgtt tcagcttttg cttcttcaat cgctttagag attgcttcta ggtcatttcc
     1501 gtctttcact aagatatgtt gccagccata tgcttcatag cgagcaccaa cgttttctgt
     1561 gaaagctttt gaagttggac cgtctagtga aatatcgttt gaatcgtata aaacgatcaa
     1621 tttccctagt ttcatatgac ctgccatcga acttgcttct tgagataccc cttccatcaa
     1681 gtctccgtca ccgcatattg catacgtata gtgatccatc acattaaagt tttctttgtt
     1741 atacgttgct gcaaggtgcg cttctgccat tgccataccg acagccattg caatcccttg
     1801 tcctaatggc cctgtagtgg cttctacacc atctgtatga tgtacttcag gatgtcctgg
     1861 tgttttagaa tcccattgac ggaattgttt caaatcatcg attgtcactt gatagccagc
     1921 taaatgaagc aagctataca acattgctga cccatgtcct gccgaaagaa cgaaacggtc
     1981 gcggtcagcc cagttttttg atgtcgttgg atttactttc aggtgttttg tccataacgc
     2041 atatgccata ggtgctgcgc ccatcggcaa tccaggatgt cctgagtttg ctttttggac
     2101 tgcttcaata cttaatgtac gaattgtgtt aacgccaagt tggtcaattt tgtcaaacaa
     2161 aataacccct cctattaatt taggtttttt ttacctttat ttcttacact ttcattctat
     2221 aagatgtcac acgaaaaagc aatctttttc agtatttttt actaaaagtt gtcatttcgg
     2281 ttgtgtaagc cttttttctt ttggatttct tttaattttt ccggggtcac gtcattgccc
     2341 tcaggatcga cgactttcat tccttcgata tgatgacgca taccggaacg aaaagcttcc
     2401 aaatactctt tgcgcaagtt gatttgttct tgttcttcgg cttttgagag accattttcc
     2461 ttctttttac gtgcaagttc attgatccgc tctatttttt caggtgacag catgctcagc
     2521 cctcctttta ctctccttca tattatataa aaactgaaaa aaaaacaact agataaacta
     2581 aataaaatac gaacattcgt ttgatttagc gctttttata tggtactatt tatttatcaa
     2641 gtgaaagaag gtgtaccttg tggcccgaca aactgaatca agacaaatcg aagtcttacg
     2701 atatatccat gaacaagtaa cccaaaaagg atacccgccg actgtccgtg aaatcgggga
     2761 agctgttcag ctttcttcta cttctactgt tcacggtcat cttgcacggc ttgaaaaaaa
     2821 agggtttatc caaagagatc cgacgaaacc tcgtgcaatc gagttgacaa aacaaggttt
     2881 agaaaagatt gggattcgtc caacaactat tccagtactt ggcgtcgtaa cagctggaga
     2941 acccatttta gcagtagagg atgcttcaga cttctttcca atccctccta atctttcttc
     3001 cgaagaaggc agtctcttta tgctgacaat tcgtggagat agtatgatca atgctgggat
     3061 attggatggt gacaacgtga tcgttcggaa gcaagaaact gctcaaaatg gcgatattgt
     3121 cattgcaatg actgccgagg acgaagcgac ttgcaaacga ttctataaag aaaaaaactt
     3181 tttccgtctg cagcctgaaa acgacttgct cgaaccaatc atcttagatc aagtatctat
     3241 attaggacga gtagtaggac tttatcgtag tcatatctat taattgctac taattaaaag
     3301 aaaacttttt aaaaagagtt tgagacgttg gtctcaaact cttttttcgc ccgggttctt
     3361 cttctttcaa atttttatca cttccctctt tacaaaccga acaaatattc gtatactaaa
     3421 tatacgaaca attgttcgca taaattaaag aggtgagaat tcatgaaatc aatgagacgt
     3481 cttggcttag tattaactgt tttgttttta ggtattatta ttggtaattt cggcatacgt
     3541 ccagctttac ttgtgtttgt tccgttattt actttgtggt tcatgttgtg ggatgaaaag
     3601 aagtaccgtc aatctgagcg gcgcagaatt catgaagatc atttctatca tgagccctac
     3661 tacagatcca ggcaatcata ataaggattg actgctaatt attcaaaaga caagaagtta
     3721 aacttttacg ggggtgtgac aaaaatcggt cacatccttt ttttcgaata aacggtgttc
     3781 taaagccagt ttttcggtat taagtcaaat tgcggaaaaa gtgatttttt aaacttctac
     3841 tggtctttgc ttgtttccat ttataaaaaa atagcgaccc tcaaaagtca gatagagaat
     3901 ctgacttttg agggtcgctt taaaatcgct tctttaagaa taacatcaag aatagcttct
     3961 tttttctgct taatattcca ttaatgtaat gatgtcatat cctttgattt tgtcgcgtcc
     4021 atggagatcc atcaattcga tcaaaaatgc gcagcctacg actacaccgc ctaattgttc
     4081 gatcagttcg atcgtcgctt tgattgttcc tccagtagct agcaaatcgt cacaaatcag
     4141 cacacgttga cctggtttaa tggcatcctt atgcaatgtc aatgtatctg ttccatattc
     4201 taatccataa gtcacttcga tggtttctcg aggtaacttc ccttttttgc ggactggggc
     4261 aaaaccgact cctaactcat aagcaacagg acatcctacg atgaatccac gggcttctgg
     4321 cccaactacc atatcaattc gtttttcttt tgcataattt acgatttgtt tagtagcttc
     4381 ccgataagcg tcaccatctg ccatcagtgg ggaaatatct cgaaacacaa ttccttttga
     4441 cggatagtcg ggaatactgg caatataatc ttttaaatcc actctttgtt tcctcctagg
     4501 ttgttaacca tttctttatg gtaggaatat cgctcaaaag caaaaattcc tcaactttga
     4561 ttttattgag ccgtcgctgg tataatctgc tctcagtcaa aggatgactt tctgggctag
     4621 cgactttttg taaaacaccg ttctctattg taacaaattt caattcaaaa aacacctgta
     4681 tcataaaaat taataatttt tcagggatac gcaaatattg agctattgct tttattttat
     4741 gacgtatatc aattcgttct tgagaatgga tcaatttaaa caattttgcg tactgttctc
     4801 ttgtgcctac cccattcaaa taggcctcat caggtgaaat ccccatcaga taaacacgat
     4861 tgaatgaata agaccgaaaa acttctttca gatccgctaa atcatctgga caatccataa
     4921 caactagaga gtttggtttt cttttttcaa ttattgcctt tacagaatct agtccttcga
     4981 aaacaatcgc agcttcctgg ataatctcag gcacgaattt caacgtcgaa gaatcaaatg
     5041 ctaaataaag gctaccttcc gacgttcggc tctgttcacg gaaacgtttt gcccgccaat
     5101 caaatacttg cagaccaccc acagaaaaat cagataccat cagctgcggt ttcttacgcc
     5161 cgttccattc attgatcgaa agctttccta ccacatctac ctgattattc agcagttctt
     5221 cttcttgagt accaaaacca aaagcgaccg catcaagctg actcgatgca tcggaaagga
     5281 caaatttcag atgctgttgg tttgctccga ttcttttgat attttctgct tggacttgtc
     5341 gaaataaaaa ctgaggcaaa ggattatccg taccaaatgg cgccaatagt ttcagctcat
     5401 caattcgctc tactgttact tcatttggca gcaatacttc atcaattctc aactcaggcc
     5461 ctctcatcaa gtcaatttga tgatcgacta tatattggtt catcttctcc tgtagtatag
     5521 tgacattttc acttggcatc gttaaaccga ctgctgcatg atgtcctccg aagtaagtaa
     5581 ataaatctcg catctggtca agcatttcaa aaagattcaa ggcttcaata ctacgtccag
     5641 atcctttagc tgatccatct tcttttaaag taaggacaag agttggttta cccgtttcat
     5701 tcattatttt cccagcaaca atgcccaaaa cgccttcatg ccatcctcgg tttaccaata
     5761 gatggatatg attctcctta ttgaccatcg ctaatgcttc ttgtgttatc tgctctacga
     5821 ttgcttttct ttcttcattg atctcattca atttttttgc ttgaacggat gcttcctctt
     5881 catcaaacgt cgcaagtaac gagacggcag gacgtggatc gcccatccga ccgattgcat
     5941 ttagtctggg agcaatcgaa aaaccgatcg ttgtttcgtc tgcgtccctc atttttacgc
     6001 cgctttcttc aaatagcgcc tgaagtccta tccgttctga atgatgaatg gcatcgattc
     6061 ctaatgaaac aaggattcga ttctcatcag tcaatgaaac taaatcggcg atcgttccta
     6121 tcgctactaa atccaaaaat tctgcaggcg gttcttccaa taatgcagaa gctactttga
     6181 atgctactcc gactcctgcc aaatctggaa atggatagtg ccccgctgga tgacgagggt
     6241 gaacaatcgc ataagcgtct ggtaaattct caggtagttc gtgatgatct gtaatgatca
     6301 cgtctacacc agcttgctga gcgtatgcta ccgcatcatt tcctgctacc ccgttatcaa
     6361 cagtgatgat caactggatt ccttcttcga tcttttcttg gtataccgat tggtttggtc
     6421 catacccatg ctcaaatcga tttggcagga atacttctac ttctgcacca agtaattcca
     6481 gtgtttcttt cattaccgtt gcactggtga tcccatctgc gtcataatca ccgtaaacga
     6541 ggattttttc tccactgatt acagcttctt ggattcggct gattgcttta tccatatcgt
     6601 gtatcagata cggatcatgt aattcttgtt cctttggatg taaaaatcgg ttgatatcct
     6661 tttcctcatg gtaacctctt tgccacagta acttaccgac aaatggagat aatttcagtt
     6721 cacggatcat ttggagaaag gattcagaag gctctgtctc gcttaacttc caatcaaaat
     6781 ttgcttgtct cactttctca ctcctaactt agttattata gcaaaggaaa tcagcaaaaa
     6841 aaagcagaaa gaaagaataa aaacagatca gatccgctag acagatgttc agcaggacct
     6901 gatcttttgt acgaccattt atgaaatatc cctattagtc aaaataattg aagctttgtt
     6961 tgggcgattg agttttttgt tcttccggcg ctttcaattg actgatttgt gcggttttcg
     7021 cttgtaactc cgcctgataa gcagcttcca actccgcacg ttcgtttcta aactcgcgtt
     7081 gctgttcttc ttttgcttct tcaattttct tttgaagttc tgtttgatat tctgacattt
     7141 cctgagtcag ctgtttgatt tgcttttttt gctgccatag tgttgccgaa gcagtcaaaa
     7201 atacaatcag tgcaccaatc agcgcagaac cgatgatcac taagatcaat ggcgcagaaa
     7261 aggaagtgaa gccaaaactt acaggaacat ttttattgtt caatacagca aaaagaacaa
     7321 taatcaaaac taaaacaaat ccaagaatca cattgctttg ctttttcaat tccttcacct
     7381 actttttgtt aaaaattccg ctggctaaat aatcaccaat cgttggaaac agcgtataaa
     7441 attttgatgc aacttctaaa ataaacggtt gattgatttc ccgttttgga tgtctcatat
     7501 tgcggacgat catttttgcc aacttggcag gttctaaaac gatttgtccg actttttcca
     7561 aatagcttcc gcttggatca gccttatcga agaaatttgt ctcgattgga cctggattca
     7621 ctgtcgtaac agctacgcca agtggtttca attctaatcg caaagcgttg gagaagccaa
     7681 ggactgcaaa tttcgtggca gaataaaccg ttgattttgc agttgccatt tttccagcca
     7741 tagaggcgat attaatgata tgaccttgtc ttctttctgc catatcgatc gcaaattttt
     7801 gtgtcaaaac catcattcct aagatgttga cttcaaacat atcgtatgct tttccaaggt
     7861 cgaatgtaag gaagtcttcg aaaatcccaa aacccgcatt gtttaccaga atatcgacgc
     7921 gcccgacttc ttccatcacc ttttcatata attcgtccac gctttcagga ttgctgacgt
     7981 ctaccttgaa agcataagcc tctttgccgc tcaagcgtct gcactcgtct ctgacacctt
     8041 ctacaaatgc cattcttcgt gcgcaactta taacgattgc tccttgcttt gctgcttcat
     8101 aacagatttg tgcgcccaga ccgcctgaac tacctgttac taaaacaact ttatcttcta
     8161 aattcatgcc tcttcctcct cgcgaaatgg aatctcaatg ctatcaaaat ctttcataat
     8221 cgtcgtgttt tcaaacactt cttgtgcttc tttttcaagc tctaaagctg cttttcctaa
     8281 atatctcgca ctgatatgag taagtagcag ccgttttgcc tgcgcttctt ttgcaacttc
     8341 agcagcttga tgagtcgtgg aatggaaata gttgtgcgcc attcttgctt catctttatt
     8401 aaatgtgctt tcatgtacca gaatatcgct attttccgca agcacaacgg aattatgtgt
     8461 ttttctcgta tcgcctaaaa tagtcacgat tcgtcctttt ttatctggac ctacgaaatc
     8521 ttttccattg atcgtccgcc catcttctag ttggatcgtt tcaccttgct tcagtttgcc
     8581 gtacagtggt ccagctggaa tacctaattc ttttagacga tccacctgca attctccttt
     8641 atgatcatgt tcaaccacac gataaccaaa actgtcgatc ccatgattta gtttttttgt
     8701 ataaacagaa aattgctgat cagtaaaaat cggggctgtt tcatttagct caatgaattt
     8761 cagcggataa cttaaacgcg tttgcgaaat acctaaagag acttttatgt attcctctat
     8821 cccttttggc ccgtaaatct ctaatggcgt atccccacct tgaaatgacc ggctgctgat
     8881 gagcccggga agtccaaaaa tatgatcgcc gtgtaaatgt gtaatgaaaa ttttaccgat
     8941 ttttctcgga cgaatagtcg ttcgcaaaat ctgcatttgc gtgccttcgc cacagtcgaa
     9001 caaccaaact tcattgcgct cgtctaaaag tttcaatgct atacttgtca catttctatg
     9061 ttttgcagga acacctgcac ctgttcctaa aaattgtaat tccataatct acctgacttt
     9121 ctttaagttc ctctttaatt ttagggtaaa aagaagggat aatcaaccgt aagtcgagaa
     9181 tgggttcaaa ttaaaaataa cgttctaaag cgatagcgtt ttctttgaaa attactataa
     9241 aaacagcagc gaacccgttt gagatcctct gctgtttttt attaatttga agatccagaa
     9301 ctttcattgt cgttggaagt ttgcggatgt ttgtccttcc aagtcttttg tgcagcttct
     9361 ttcgcatgat tttcagcttc tttcgcatca tgcacatctt tttcgacatc ttcataatcc
     9421 aagcgagtaa tttctccgcc taattccatc attaccaatt gattcagtgg gcgattgtcc
     9481 tcttcatcag caatcaagat cagtcctgta gctccttcac cgattttatt tcctacaaag
     9541 tcgaacacgg tctgggcatc ttttatttct ttggcatctt gtgtcgcacc gatcattcct
     9601 ccggcaaacc atcctaataa aatccctagc ggaccaccta atacaccaac caacattccg
     9661 attaatccac ccgtagaaga tttgttatta ccggtaaagt cgataaaatc ttctattttg
     9721 aattgatgtg tcccattagg atcatggctg acaactgcca tctgttctcc tttaatcgaa
     9781 cgaacagcat gtaacttttt gatttctgaa aatgcctgat atgcctggct ttctacttga
     9841 aaatttaaaa tgattactcg tttgctcatt aaaaacgccc ctttcatacc ttcttgttat
     9901 ttattttacc tttaattgta aaataagaaa agaaaagcac tctttttttc caataaaata
     9961 gggctgtgac aaaagtcgta tcacagctcc tttttccgaa taaacggcgt tcttgaagct
    10021 gatcacttct gtcacaacct cccttaaatc tgaatctata ttttttggta tttgttttta
    10081 tttgcttgcc tattcgacaa attcaaattc aaactcaccg atacgtacaa ggtcgccatc
    10141 tttcgcaccg cgtgcccgaa gagcttcatc cacacccata ccacgtaatt gacgagcaaa
    10201 acgcatcact gtttcatcat gatcgaaatt cgtcatttgg aataattttt cgatcttctc
    10261 accagataag atccacgttg catctgaatc acgatcgatt tggaactcag gaccttctgg
    10321 attgaatcca tagtgtacag tttcttcttc cagttcttct tcgtacaatg ggaattctgg
    10381 cgttacttct aacaaatctg ctgtagcatt caataacgcg tccaatcctt gtcgagtcac
    10441 tccagaaatt ggaaatactg ggatgtcatc agcaaattca tcttcttttt ccttgttcag
    10501 ctgttctttg aatttcacta gattttccgg tgcatccggc atatccattt tgtttgccac
    10561 gatgatttgc ggacgctcta gcaagcgtaa gttataagta gataattctt tgttgatggc
    10621 aagatagtct tcataaggat ctcgtccttc catcccactc atatcgatca catgtaaaat
    10681 tactcgtgtt ctttcgatat gacgaaggaa ttgtgtaccc agcccaacac cttgcgaagc
    10741 tccttcaatc aagcctggca agtctgctgc ggcaaaactt ctgccatcac ttgtagtaac
    10801 cattcctaga ttaggtacga gcgtcgtgaa atgataagcg ccgatttttg gacgagcaga
    10861 tgaaataacg gatagtaaag tcgatttccc gacagatgga aaacctacaa gtccaacgtc
    10921 tgccaatact ttcaattcta gttcgatttt tcgctcttgt cctggttcac cgttttcagc
    10981 aatttccggt gcaggattcc gaggagaggc aaaacggata ttccctcgtc caccgcgtcc
    11041 accttttgcc acaactagtg tttgaccatt ttcaattaaa tctcctaaaa gagcaccagt
    11101 ctccgcatct cggacagtgg ttccttgtgg tactttaaca taggtatctt ctgaaccacg
    11161 accgtgcatc cctttactca tcccattttc acctggctgc gctttgaaat ggcgattgaa
    11221 ccgaaaatcc atcaatgtac gtaacccttc atcgacgatc aagatgacat cgccgccacg
    11281 accaccgtct ccgccagccg gtccgccgtc aggaacgtat ttttcgcgac gaaatgcaac
    11341 cattccgtct ccgcccttgc cagctttcac atcgatcgtt acttgatcta aaaacatgga
    11401 cataattaag tcctcctatt attcatttat ttatttgact gcctgaattt ccacaataaa
    11461 caaaagtctt acttatttta tcggtgaaat ctgattttgt ctatcatttc agcaaaaaga
    11521 ttgtttacct tcttcttttt ttatcatttg gtaaggtttc caaccttttt tctgctacca
    11581 agtataattt tttgacaaaa tattctttgc gtagcagaat aacagtgtat taattgtatt
    11641 aattgtatta attgaggatg ccgtttcaca gcacccctaa taaaggagga acttttgata
    11701 tgacagtaaa agtaggtatt aacggatttg ggcgtattgg ccgtctggct ttccgccgca
    11761 tcaaagaagt ctcagatgat attgaagtag tagcaatcaa cgacttaaca agtccaacta
    11821 tgttagcaca attattgcaa tttgactcta ctcatggtac ttatcctggc acagttactg
    11881 caacagaaga ctcaatcgta gtggatggcg aagcaactcg tgtttatgca gaacccgacg
    11941 caagcaaaat cccttgggca aaagaaaacg gtgtagatat cgtactagaa tgtactggtt
    12001 tttatacatc tgaagaaaaa gcaaaagcgc atttagatgc tggtgtcaaa cgagtagtta
    12061 tttctgcccc agctggtgct atgaaaacca tcgtctataa cgtcaatgat gatacattag
    12121 atgaaaacga caaaatcatc tcagcaggtt catgtacaac aaactgttta gcacctatgg
    12181 cttatttctt aaataatgaa tttgggatcg aagttggtac aatgacaaca gttcatgcct
    12241 acacttccac acaaatgctc ttagatggac ctgtaaaagg cggtaatttg cgtgctgctc
    12301 gttcagctgc tgacaatact atcccacatt ctactggtgc tgcgaaagca atcggcttag
    12361 ttatccctga gctacaagga aaattacaag gacacgcaca acgtgttcca gtcgttgatg
    12421 gttcattaac tgaattggtt tcagtattga aaacaaaagt aactgctgat caagtaaacg
    12481 aagcaatcaa aaaacacaca gttgacaatc cttcattcgg gtatgatgac cgtcaaatcg
    12541 tttctagcga tgtcattgga acaactcaag gttcgatctt tgacccaacg caaacagaag
    12601 taacaactgc tggtgatttc caacttgtta aaactgttgc atggtatgac aatgagtatg
    12661 gatttacttg ccaaatgatt cgcttactag aaaaattcgc taacttgtaa tttgatagat
    12721 caatcgataa aagaagcctt tgactggatc cagtcaaagg cttctttctt ttcatcccct
    12781 acttttaaac tcgttcaatg aacatattgg cttaaaaatt gttggactac ttgctgatat
    12841 ttttcaggat ctgtcttgta tgcttccgca tgctcggctc cttttacaac atacttttct
    12901 tttggtccct tcgttgcacg atagacctta tctaacattt caaatggtac aaatgtatct
    12961 tcgtctccat gtataaagag cattgggcgc tggtttttct tcaattgttc cactgcattt
    13021 gcttcaccga aaaagcagcc agcacggact tttgtcacta gactcgttac ttgcataagc
    13081 ggaaatgctg gaagactaaa catatcgtct agctgataag caagctcatc atgaacggaa
    13141 gaataaccgc aatcttcaat gattgctttc acattatctg gtagtttttc tccgctagtc
    13201 atcataactg ttgctgctcc catgctgaca ccgtatagaa cgatttcttg cgattttcca
    13261 ttgttttcta gcactttgtt tatccactgt acatagtctt tacgctctgg ccatccaaat
    13321 ccaatgtaat ccccttcgct ttttccatgt cctcttgcat caggaacaag gacattgtaa
    13381 cccatatcat gaaacatctt tgcgtaattg gtcatcgttt cagcgtttcc catatagcca
    13441 tgagccacaa gagctgtttt ttcacttttc gtttcagcag gaagataaat cgctgataat
    13501 ttcagaccgt cttttgaagt gatggtccaa tcgcttcggt tttcttttga actaaaccat
    13561 ttatgtgcat ccgtttcttt ggatgtctgt gttgtaccag gtgtatcttc gtctaaaaag
    13621 tctttctcag aaggcacaac agcataatta taaaaataat tccctgcaaa cactaacgca
    13681 acaatcagag ctaaagcgac gcctaaaagg attttcatcc aaagtttcat aaatcatcca
    13741 tctcatttct cttttttcat ataaccttga attagtataa tcaaagaatc tctactatgc
    13801 aatgttcatt tttataac
//
LOCUS       DAZULR010000060        13569 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.061, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000060 DAZULR010000000
VERSION     DAZULR010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13569
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.061"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..414)
                     /locus_tag="ACG8ZV_002286"
     CDS             complement(<1..414)
                     /locus_tag="ACG8ZV_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFS4997567.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKD"
     gene            complement(411..1064)
                     /locus_tag="ACG8ZV_002287"
     CDS             complement(411..1064)
                     /locus_tag="ACG8ZV_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFS4997568.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            1352..1872
                     /locus_tag="ACG8ZV_002288"
                     /pseudo
     CDS             1352..1872
                     /locus_tag="ACG8ZV_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(1870..2589)
                     /locus_tag="ACG8ZV_002289"
                     /pseudo
     CDS             complement(1870..2589)
                     /locus_tag="ACG8ZV_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010745868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
     gene            complement(2540..2749)
                     /locus_tag="ACG8ZV_002290"
     CDS             complement(2540..2749)
                     /locus_tag="ACG8ZV_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997569.1"
                     /translation="MDVLREYSSLFTEAYLLEQFGYKIPFADYQQGVGTAAELSFYEG
                     ISQAVGRPVDAEHFEQRISSTGKSE"
     gene            complement(2731..2799)
                     /locus_tag="ACG8ZV_002291"
                     /pseudo
     CDS             complement(2731..2799)
                     /locus_tag="ACG8ZV_002291"
                     /inference="COORDINATES: protein motif:HMM:NF024811.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
     gene            3026..4299
                     /locus_tag="ACG8ZV_002292"
                     /pseudo
     CDS             3026..4299
                     /locus_tag="ACG8ZV_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(4406..5437)
                     /locus_tag="ACG8ZV_002293"
     CDS             complement(4406..5437)
                     /locus_tag="ACG8ZV_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4997570.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(5444..6274)
                     /locus_tag="ACG8ZV_002294"
     CDS             complement(5444..6274)
                     /locus_tag="ACG8ZV_002294"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4997571.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            complement(6271..7086)
                     /locus_tag="ACG8ZV_002295"
     CDS             complement(6271..7086)
                     /locus_tag="ACG8ZV_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4997572.1"
                     /translation="MKEMKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLA
                     NYSDIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLA
                     ANFAGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYP
                     SMKEVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALT
                     SSNVNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            complement(7083..7907)
                     /locus_tag="ACG8ZV_002296"
     CDS             complement(7083..7907)
                     /locus_tag="ACG8ZV_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HFS4997573.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            complement(7897..8997)
                     /locus_tag="ACG8ZV_002297"
     CDS             complement(7897..8997)
                     /locus_tag="ACG8ZV_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFS4997574.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            9175..9960
                     /locus_tag="ACG8ZV_002298"
     CDS             9175..9960
                     /locus_tag="ACG8ZV_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HFS4997575.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            9993..10376
                     /locus_tag="ACG8ZV_002299"
     CDS             9993..10376
                     /locus_tag="ACG8ZV_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HFS4997576.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            10452..10583
                     /locus_tag="ACG8ZV_002300"
     CDS             10452..10583
                     /locus_tag="ACG8ZV_002300"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: protein motif:HMM:NF012387.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFS4997577.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            10552..10788
                     /locus_tag="ACG8ZV_002301"
     CDS             10552..10788
                     /locus_tag="ACG8ZV_002301"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFS4997578.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            10800..10886
                     /locus_tag="ACG8ZV_002302"
                     /pseudo
     CDS             10800..10886
                     /locus_tag="ACG8ZV_002302"
                     /inference="COORDINATES: protein motif:HMM:NF012387.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
     gene            complement(10866..11837)
                     /locus_tag="ACG8ZV_002303"
     CDS             complement(10866..11837)
                     /locus_tag="ACG8ZV_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HFS4997579.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
     gene            12471..>13569
                     /locus_tag="ACG8ZV_002304"
     CDS             12471..>13569
                     /locus_tag="ACG8ZV_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element ISEfa7 family transposase"
                     /protein_id="HFS4997580.1"
                     /translation="MQGVIAMMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFE
                     FIYPIVEATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDTNVAYRWFLGYS
                     FEEKIPPFSTFGKNYVRRFRETTVFEDIFAYILEQAVKAGFVTEDNLYLDSTHIKANA
                     NKHKFTKEMTHDEAKAYQDELEDEINRQRIEAGKRPFTLDLEKEVKLKERKISKADPE
                     SGYYVKGEREKQFAYSVHTSCDDNGFILSTIITPRNIHDSQVAFQLVKQSKRLFPEIN
                     CVVADAGYKTPKFVHFLTHLNLRPCLPYSRPKGKKELLSKNEFLYDEYFDCYICPQDQ
                     MLAFSTVTREGYREYKSNPKECVNCPLLNQCT"
BASE COUNT         4090 a         3011 c         2466 g         4002 t
ORIGIN      
        1 atctttcgca tctttttgca tatcagctgt agaaacaaat tgtagatttg tttttttacc
       61 atcattaagc tttatttctc tttcttcaat tatcaaagaa ttactatcac tttctaaatt
      121 aacatttata ttatctttga tttgtatttc attcttatta tttttttctt ttatgaatac
      181 ttttatttca ctactcttgg aataaaactc caaagtttgt tctatatatt ttatttcttt
      241 tccattcata ttactagaaa tttcatttgc catattatga atcttttctt ttctcgtctc
      301 caaatatgtt ttaggaaaga taaaaaaaat taatgaatga actaatataa ttattattcc
      361 aagaacagaa aatatttgta tgaacatttt tggaaatatc tttaattttt tcattttctc
      421 tccaatttat atcctacatt tcttatagta gttatacagt ctaattgtaa tttttttcta
      481 agttctttta tatatacatc tattactcga tcataaggag tttcttcgct atctttccat
      541 acataatcaa taatttgcat tcttgttaac acttgtccat tattatccaa taaacatttt
      601 aatacttcta gttcttttgc atttacatct atttcttcac catttatttt agctgtatag
      661 ctattaaaat taaccgatag atccttatat tcaaacttct ctaaatgtcc ataattcttc
      721 ttaattaaag aatctattct agcttttaag accggcaatg aaaatggctt ttctacatat
      781 ccgtctacta aattagtaaa tgcatcaatt ttatattctt catcactaaa tgcagtcaag
      841 attagaattg gtaaattgct tttctttcta atttctttca acacttctaa accatttata
      901 aaaggtatct gaatgtctaa gataaccaaa tttatatcgc tattaaattt tgacaaggct
      961 tctcttccat ctttagcttg aataacagta tatccaaatt ctgaaagata ttcacttatt
     1021 ccctctctta tcatattatc atcttcaaca gttaatattt tcatatatac ctccacttaa
     1081 gcctatacac tagatattat acagcatatt atggctctat aatatctagt gttggtgacg
     1141 ccttctgttg ccaatacttt ttcttttttt taataaatgc aaacagacac cttgaaatcc
     1201 tttagaaaaa aggcttctat aatattttgt gttgttggaa aatcgaaggc gattttctac
     1261 taacactttt tcttcgtttc aactcaaaaa gagactcact tttggtaaaa tttagtcgac
     1321 caaaacatca ccctaccaaa ggagtcgctc tatggataat catactagaa aattactcgg
     1381 attaacagat aaacatttat tttttgatga agaatggctg attgaaaaag aatataaagg
     1441 cgttcaagcg cagtttatta aagggagatt ggatgactca ccttcccatt gtgaacactg
     1501 tggatcgatt cgtattatcc gcaacggttc ctatacgaca cgtactcaga tgttgaaagt
     1561 caaagaaaag ttgactattt tagaattaaa acgtacccgt tttctatgct atgattgtgg
     1621 gcagaccttt tctgcgaaaa cggacttagt tgatgaacat catcaactaa caaaggaact
     1681 gaagcaggcg attctcatag aactgtacga aaatcaatca cgtaatctga aaatcagaag
     1741 aagtaccgtc ggctcaagcg atattggaaa ctcttactca aagattccac gacattggag
     1801 ccgctcaaac ggcattatca tcgactgttt aaacgaccaa ttagtcaaac agaaatcgtc
     1861 gatgaaccgt tgtgcacaat ggtgtcctga acgtacagcg acaccttcca tatccagagc
     1921 agtcgccaca tcacggggat ggatgccatc caaattaaaa gcaaccacgc cagtatgatg
     1981 ttcaggatct tgcggtccgt aaatggtgat accgccgatc gcttgtaatt taggtaaaac
     2041 gtaggcaacc agttcttgct cataacgatg aatattctcc ataccaatct cattcaagta
     2101 atcgattgct cctgcaatgt tcggagtacc agcttcaaat ttccatggca gctctttcca
     2161 tgaactatcg taaagattga caaaatctat catttcaccg ccgaattcga ctggctccat
     2221 ttgttctaac aattgacgtt tgccatataa tacaccgatt cctgtcggcc cgcacatttt
     2281 atgcccgcta aaggcgaaaa aatctgcatc caacgcttgt acatcaactg tcatatgcgg
     2341 tgctgcttgg gcaccgactg gactatcctc aactacaaca gcctgttcaa ccctcagccg
     2401 tttcaagcac aacaaataac cttctggatc tggtttgccg acctgaagat catcgatcgt
     2461 cacaaaggaa tcaatttttt ccttaatcat cggatgtgct tcaaaaaaat agtctagctc
     2521 ccgcagttca gaattgagac tactccgatt ttccagtgct gctgatccgc tgctcaaaat
     2581 gttcagcatc cactggtctc ccaaccgctt gacttatccc ttcataaaag gacagttctg
     2641 ctgccgtccc aacaccttgt tgatagtctg caaaaggaat tttatagccg aactgctcca
     2701 gtaaataggc ttcagtaaat agtgatgaat actctcgtaa aacatccatt cactgtcaat
     2761 catcgtccca tcaaaatcaa aaataagtgc tttggtcatc ttctttcccc cttacccaaa
     2821 acaagcaaaa gctgtgtcct gctctctcta cagtatcagc ataaaaactg ccgtctgaaa
     2881 agtcaaaggt gaaagaaatg tggcgctata atttctagga ctgatagtaa atcattctat
     2941 cagtcctttt gagcataaaa aaacaaaaca tacagaagct ccgttagaat tgaatcacca
     3001 caacacaatc aaaggagcgt tctgtatgcc tgatcttcat cttatcaaac tattactagg
     3061 aatcaaagat ggaaacattc aaatcactca tgtcgagaag aaaaaaatac attcaatcaa
     3121 cagtatcgtt gtttctgcca cgctcattaa aacgattcag ccctgtcctc agtgtaaaca
     3181 ggtgaatcaa catgggctga tcgttaagaa cggaaagaaa aaatcgctgg tccttctcaa
     3241 taagtgtgcg aatcaacgga cttatcttgc tttggcaaag caacggtacc tctgtcgtgg
     3301 ctgtcacacc tattttacgg cgaataccta cattgttgaa aaaaactgtt ttatcgccaa
     3361 acaagtacat tataaaatat tggaggaatt gactgaaaaa caagcaatga cgacgatttc
     3421 taaacattgc ggcgtttctt ggtcaaccgt ttcgcgaaca ctcgcttctc tgctccccat
     3481 gacaaacgtg aaaataaatt ggttgcctcg ctgttcattg gtagatgaat ttcgttcatt
     3541 gaaaaatcaa gtcggtccct attctttttc ttgtatggat ggcgatactg ggaaattact
     3601 ggatattctt ccttcacgta agaagaaaga tctcatttct tattttatgc aatttgaacg
     3661 acgtgcacgt ttaaacgtaa aaatactcgt aacagatatg aacgcctctt atgctttgct
     3721 gataaaagag tgctttcctc atgccaaact cgttgtggat cgctttcaca tcgtcaagca
     3781 cctcattcgc agttttaagg atatttgact atgagtcatg aaaagcttcg accgaaacga
     3841 tccaatacaa gccaaacact atcgacaagt gaaggcttta tctcgacttc tgatcaaacg
     3901 acaggacacg cttgtttatg ataaatggac aaaatggcgt aattttggtt gggcctattt
     3961 aaccgaaagt gaagtcgtag aacgtctact ttctacttct gatgaactac gaatagctta
     4021 tgcttactat caagaaattc ttcaagcttt ttatgacaaa gaagcggaca tcttctttca
     4081 gcttgtaaaa acaatgccca agtcggttcc aagagaactg catcatataa aaaaagcgtt
     4141 tataaactat gaatccggca ttcgtttagc cttagagttg ccttactcaa atggcaaaat
     4201 agaaaatctg catacccaca tcaaagcatt gaaacgaata gcttacgggt taggatgaga
     4261 accagaattt tcttaatcaa tcatctgatc acttattaaa cataaaaaaa catctaaagc
     4321 agaaaatcaa ttctacctta gatgttctta tatcactcta tcagtcctat ttgacaaaga
     4381 gccagaaatg tttgccgact atacactagc tttgttgtgc aaaatgctga gtatcaattt
     4441 ccacagggat tgctagaata tctttcagct gaatgtataa ggcatcgcta attttctctt
     4501 cccgatcgtt caaccgatcc actaaaattt ctttgccctc cagcgtttga aaaacatacc
     4561 gttgaatgtt gcctaaaata aatgattcct tccatagaac cggaatctta accccctgag
     4621 gaaccggttc aaattgaatc agctccggtc ttaaataata aatgcagcga ttgcccttag
     4681 cggaaaactc gtgggtatac tgattcagct cataccattc gaaacgatta tagttgccga
     4741 taaattccgc aacaaatcgg ctctgaggat tctgatacaa ttccttcgag gtggaaacct
     4801 gagccacccg cccagcttcc atcacaaaaa tccgatcact gattcgcatc gcctcttctt
     4861 ggtcatgagt cacaaaaatc atcgtcatcc ctagcgattg ctggatagcg cgcaaatccc
     4921 gctgcagctg ttttctaatt cgggcatcca aagcacttaa tggctcatcc agcagcagga
     4981 ctttcggttc agtgaccaat gagcgagcca gtgccacccg ttgtcgttga ccgccagaaa
     5041 gaaactggac atttttatct gcctgctccg tcatatccac caatgatagc atctcaaaaa
     5101 ccttttcctg aatcacctca ggactcagct tctttacctt caaaccaaag gctacatttt
     5161 caaaaacagt catagttgga aacaatgcat actgttgaaa aacaaagccg atattgcgat
     5221 ccttcgtagg cttatcggca atattctcat tgtccagcac aatctcaccg ctctttggtt
     5281 gttccaatcc cgtgatacag cgcagcaacg tagactttcc gcacccgctg ggacctagta
     5341 aagtaaccag ctcacccttt tcaatctgaa tttcatcaat agctaaaatc tgtttttcat
     5401 caaaaaacag attgagatca tgtatttcta aaaacatttt ccgtcacaac tcctttaagg
     5461 gcttcttttt cgactgcttc tcttccctcg tctgcttaag ggacagctgt tgcttttgtc
     5521 gataagtcag cataaaggta gttaaagcaa ttcccaccat aaacagcaaa tacaaaacca
     5581 tcacagcgct agccaaatgg ccgttttcgt tcatccgccg cagcatatag atgcgtaccg
     5641 tctgaaatcg accgccaatc aacaggttcg tcagcatgta ctccccaaaa accgaagaaa
     5701 aaatcatcag agaaactagg gtcacaccga tacggatgtt tggaaacagc acctggataa
     5761 taatcgtaga catcggggcg cccaaggttt ctgctgcatc cactaattcc ttcagattaa
     5821 ttaagcgcat ctggttgtta agactaagat agacaatcgg caacgccgta ataaacaatg
     5881 cacctaccaa cactacaaac attgggatac cagtttcagc atacgttcga agcaaagccg
     5941 ttaccaaaat cactcctggt aaagcatacg gcagcaggag cagcttttcc agccaacgat
     6001 tcaaacgagg gaaatacaaa tgaatccaaa taatggtggg aatcatcaac aacagaatcg
     6061 tcaccaagac cacacctgct aataaaagtg agcgacccac cgcagcaata aattccctgt
     6121 ccgtcagcag ctgttggaac cattgcaagg taaaatcact aggtaaaagc gattttgacc
     6181 atttagtgga gctggcatac aaaatcgttc caataatcgg cagcaagtaa tacaggacaa
     6241 agcagaacaa aatcggtttt attaactttt tcacgtctgc accaccttgc ctttcttttg
     6301 aataatcaac attgccgtta ccagcaggac acctaaagcg actgccaacg cactgcctaa
     6361 attaggcttg gcgaacacat ctcccgacac taaagccgca attcgaatcg ttaaaagatt
     6421 tacattactg ctggtcaggg catacgctgt ttcataggtc cccatgccat tagcaaataa
     6481 gatgacaaag gtgctggcaa tcgatggtcg caaaaaaggc aaagccacct tgaaccaagc
     6541 atacgctgat gaagcgccca gcaattgtgc ggactccagc cattcctttt tcacttcctt
     6601 catgctggga tacaaaaaca agacccctaa cggaatttgg aaataggtat acgtgatggt
     6661 caatccccac caagaataca aattgaagtc cgctagaaat ggcaaaatca ttttcagcac
     6721 acctacattc cccaacaaaa taataaaaga gaatgccagc ggaatcccag caaaattagc
     6781 tgccaaattg gaaacaaagg tgattttctc ctgcaattta gtcgatagat tcattaagca
     6841 taaacataaa ataaacgtcc cgattaaccc aatcacactg gagctgacag caatcagtac
     6901 gctgttaaca aaggcctgtg tgtaatattt gttgctgaaa atatcactgt aattggccaa
     6961 tgtccactgg ttagttaaat cactgtgcaa gctgcacaga accataaaaa gcagcggcag
     7021 cagtaaaaat gcacagaaga taaaggaggc aggaaccaga accaagcgtt ttttcatctc
     7081 tttcatcccc tcatcaattc ttgaatgtcc tgcattttct ctgacggtgc aattcctaat
     7141 aaccagcaaa acaatggagc cgccagcagc tgtggtacag tttgttcctt cagcttttgg
     7201 cgtttatttg aaatcaaata aaaaggaact tcacgatgtg cagccaagct gccgccatgc
     7261 agtccgtgcg catccatccc gtgatccgca gtcaccacga cttgataacc tttttgcagc
     7321 cattcaggaa ggtaaatagc caataatctg tccgcctgat taaccgctgc tgcatattca
     7381 tgagaatcgg cggtaaattt gtgaccgaca tcatcaatat tcatcgaatg tacgaccaaa
     7441 aagtctggct gatactgatt cactaaataa tgggcatccg caaataaatg cgaatcaggg
     7501 taagtgtcct cactataaaa gatgccatgc tgaatcagtc gctcctcctg atgctggatg
     7561 cgatcaacca aacgattata gggggcttga ttgtacaact cgctgtacca gtggtaagcg
     7621 gcggctcctg tttttccgcc agcttcctta actaattcaa acagcgacca ctctttggat
     7681 cgctgagcat ggtaattact atagatgcca ttttcatagg ctggaacgcc ggtcatcagt
     7741 acttcgtata acggacgtga attgctgggc agctcacttt ttaccttcaa taagcttgct
     7801 tgctggtgct caactaaatg attcatgaac ccaagctggg cgacggctgt gtcgtagcga
     7861 cagccgtcta gtataactac aatcagtttg tcaagtctac tttgcatagg tcagtacctc
     7921 cgcctgccaa agctctggaa gctctacaga ggtcttgttc caagcttcat tgtcttcaac
     7981 tggcaccgcc gcttcataag catcctccgg cagtaatttt tcagctactt ctttaggcag
     8041 ctctaccttg cgaataggtc gcgcatagcc ctttgccaaa ttgatttgcc cttcatcaga
     8101 taaaatatat tcccgtgcta gctttgccgc attgggatga ggggcatttt tattgattaa
     8161 ggttgtatac ccgctaatga tggagccgtc tgttggcaca gttacctcaa aacgctcgga
     8221 gtcaatttgg tcacgataat ttagtccatt gaagtcccaa acaactgcca catcgatttc
     8281 acctttttca agatttgcta cgctggcatc aacggtggac aaacggcctt tttctgccat
     8341 ttttttgtag taattcagac ctggctgaat atccttttcg tcacctccgt tggcaatcgc
     8401 cgcagccaat acagcaaatt gtgcttggtt ggcaatcgtc acatccccca cgctaacttg
     8461 atagtcaccc tcttgcagct ccttccagct agtcggtgct tgcttcacat tctctttatc
     8521 ggtgataaag gaaatggttc ccgtatagct taacaaccaa tccccatcat catcctttgc
     8581 ccaatccgga atttcctccc aatagttggt cttataaggt aaggttaact ctttgctttc
     8641 agccaacgga ccgaagctga taccgacatc accaatatcg gcggttccat tttttccttc
     8701 tgattcaaac ttagccaatt cttctgcact ggacatatcc gtatccacgt gacttaagcc
     8761 gtattctttt tcaaggtcgt tccaagtgcc tacccaattt gcccaagtat ccggcattcc
     8821 caagctggca atctctcctt cttccttggc tttttctata atcgtatcta aagagtcgtc
     8881 tgccgcagcc gattgcttcg ttgcttcacc tgagccgcag cctgtcagca ggatacttac
     8941 tgttgctgca caaaataaac cgatagtcat gttacgaatt ttttcattca ttttcattca
     9001 ttcttctccc ctttcgataa ttccattcta acaaagcttt gtaatgagag aatcagtttc
     9061 ttgaaaaggt ttcatgaaca atgtaaaggt tgtatatggt ttgtaaattt cgacgaattc
     9121 ccgttaacct tctaaagctt ttgcggtatg atagtagaaa aaaggaggct ccctatgcag
     9181 tattatgatc agcatctcca cacgtatttt tcctttgatt cagaggaaaa atttgaaaac
     9241 tatttagcct atcagccgga gtttttcgtt tctacggatc actttgattt aaacaatcca
     9301 tctaccggaa aagatgacat tccggattat ccagcctata taaacaaact ggactcttta
     9361 aaagaaacct attccaccaa atttctgcga ggtatcgaga ttggcgttgt tccaggacaa
     9421 gaagagcgga tcgtggatta cctcgctcag catccttatg atttaaagct ggtaagtatt
     9481 catcaaaatg gccgctttga ttatatggac gatgtggttt taaccaaaga tcccattcaa
     9541 actaccaagg aatattttga tcagatgttg caggtcttga cggattttcc agaaggagat
     9601 attttgactc actttgatta tggattacgc cgcttcacct tcacagcgga agaattcgcg
     9661 gagcattttg aggctcagct gctaacgatt ttcaaaaagg ttgttgaacg agaattggcg
     9721 atggagttaa atgccaagag cttcttgaaa tacggcaacg aagaccttta ccgttatgcc
     9781 gttcctttgt atcaaagtgt cggcggaaag ctctttacct taggctcgga tgctcatgtt
     9841 gccgaagatt atcagctggg ctttaaaaaa atgagtcagc tgttggcaga ctgtcaggta
     9901 gaaaagttgc tagtcattca aggaaaagaa cgccgcctga cgccgctgcc gattttgtga
     9961 ttcctatata atagaagaaa gtggtgaaaa aaatgagcaa cctgtgggac tacaatcaag
    10021 aggcacccat ccattattta attgcgcgac attgggatgc gttgaaaatt gaggcggttt
    10081 gccgatcctt gttagcagcc gttccaaaac aacaactgga aaattttttg gtggctgaca
    10141 gcttgcagcg ggaaaaagtt caggcttatt ttgcagcctt taaagatcag cctttggaat
    10201 atttgcatgc gcagtttcat cttttttatc aagtagccgc cccagatgac tacaacgatt
    10261 tacgaggaca gctgcaattg acctttcaag cggatgaaac cgcctatacc gttttattgg
    10321 gaatggctcg ccttggtgat caggcgaagg tcgagtggcg gattttcgat atttgatggc
    10381 aggatcaagg cgtttcagtt gcaaaccttc ctctctttca attagaaaaa ccgcagcagg
    10441 aagaagtttg tgtgctggtc accgatgctg gtgaaattcg tctccgctta tttcctgacc
    10501 aagctcccct ggctgtagcc aactggcgct ccctagctga gcaaggcgtt tatgacaaca
    10561 cacctttcgg ctcgtgtcat taaggaattt gttattcaag gtggcgcttt ggatggttct
    10621 ggtgatgaag ctgtttccag ctatgagggc tttttcgctg atgaagtgca tcgcggactt
    10681 tatcatttta atggcgcctt ggccttaggg gaccacggcc cccacaccaa cggcaaccag
    10741 ttttttattg tgcaaaacac aaaggcgcag gctgacctgc taatgtaaag caagcatact
    10801 tggagcttgg aggactaccg gagctggatg gtcgttatac tgtttttgga caggtatacc
    10861 aagggttaga aatcgtagca gcgatcgcag ctcagccgac aaacagtgaa gatgtaccga
    10921 ttgagccagt gttcattcga caaattaact tcgaaaaaac atcgtaaaaa gacactcact
    10981 gacttcagca aaagctctat tcttgagctg gctgcagcta gtgagtgtct ttcatttatc
    11041 cataagataa agcttggatt caataaataa ataaatgttt tggttaaagc tgtgaccagc
    11101 aaatgaggaa ccgtgcgagc cagttgatct gccaatgcaa acatttcttt aggtgaaggc
    11161 gctggcgtgt ctgccaacgg atactccagt cccaatgctt ggtaaccgtg cataccatag
    11221 cagtggtacg gtagtaattc taacggtacg aaccgatcaa gatctgccac aaaacaagca
    11281 atcgtcagca gctcggtcag gttcatattg atacctggaa ccacaggaac tcgaattcgc
    11341 acttcgcagt taggatactc aattaaaaag cgacgaatat tcttcaaaat ttgttggtta
    11401 tctaagccgg tccattgttt gtggagcttg ctggtaaaca tttttacatc cacaaacaat
    11461 gtatccacat agggagctac cttttggatt tcattataag caccacaaaa gctggtttcc
    11521 agtacggtat tgattccaat gtatttcgat ttttgcaaaa tttctttagc aaaatccgcc
    11581 tgaaccagtg cctcgcctcc gctaatggtc actccgccat ccgagtgaaa gtaaaaaaca
    11641 gcatccttct caatctcatc cattacctct tcagcggtca tggtctggcc aaatcctttt
    11701 tcaatctgct tgctttgtga ttcgggaatc gaacaccagg cacagcgtaa tgggcagccc
    11761 tttaaataaa caacggtccg taaaccagca ccatcatgta gagaaccctg ttctattctt
    11821 aatactgttc cttccatata gatttttgaa ttacacacta gtttaaacta aaacacacaa
    11881 ggaaaaactt accatttaat cataaaatta gctcatataa atatactagg atgtaaaata
    11941 gactggtcaa aatctggtca aaaaagagga ctaatacagg tagtcctctt ttttgttatt
    12001 ttaatattct aaatcatttt ttattggttt attcccttat tcgatgtaga ctcaaatcac
    12061 tatatcacta gatatcaaac ggcgtcatac ggaatcaaaa acatcaaatt tgacctgtta
    12121 aatggtcatt gaataacatt caaaatcaat aaaacggagt cagacacgga gtcaaaaacg
    12181 ctgagagtaa aaaatatata cagccttgta ggtaaagtac cacagggctg tatatttttt
    12241 atttcagatt accttaaatg attccattta ctttttatct cattttttcc tactagttag
    12301 tatcaaatac tctcctattt tctcaataaa ctatttttgg atacatggta tctgaaacag
    12361 ctaaaacctt gtcattacag caaaaaatca cgttatccag actgtagaca aagtccattt
    12421 tatggatgat gtctacagtc ttttctttta taatagattt atgaaaacga atgcaaggag
    12481 tgatagctat gatgtctaaa aacaatacga atggtagaaa tcaatttgcg atgcttacga
    12541 ttgatgatct agttcctcaa gatcatctcg ttcgaaagat tgatgccgcg cttgattttg
    12601 aatttattta tccaatcgtc gaagccactt actccgattt aggtcgccca agtatcgatc
    12661 cagtgattct gatcaaattg gtgtttattc agtatttatt cggtatccgt tccatgcgac
    12721 aaaccattaa ggaagtcgat accaatgtcg cttaccgctg gtttttaggc tactccttcg
    12781 aggagaaaat cccccctttc tcaacttttg gaaagaatta tgttcgccga tttagagaaa
    12841 cgacggtgtt tgaggatatt tttgcctata ttttagaaca agcagttaaa gcaggttttg
    12901 taacagagga taatttgtat ctggattcta cccacatcaa agctaacgcc aataaacata
    12961 agtttacgaa agaaatgacc catgatgaag cgaaagccta tcaggatgaa ttagaagatg
    13021 agatcaatcg tcaacgaata gaggctggaa aacgcccttt tactttggac ttagaaaagg
    13081 aagtgaagct gaaagaaaga aaaataagta aagctgatcc ggaaagcggc tactacgtca
    13141 aaggcgaacg agaaaaacaa tttgcttatt ctgtccatac ttcatgcgac gacaatggat
    13201 ttattcttag cacaatcatc actcctagaa atattcatga cagtcaagtc gcctttcagc
    13261 tcgtcaaaca atcgaagaga ctttttcctg aaatcaattg tgttgtcgct gatgctgggt
    13321 ataagacacc taagtttgtt cactttttga ctcatttgaa ccttcgacct tgtttgcctt
    13381 attcaaggcc caaagggaaa aaggagctat tatcaaaaaa tgagtttctc tatgacgagt
    13441 attttgattg ttatatttgt ccgcaagatc aaatgctcgc tttttcaacg gttactcgag
    13501 aagggtaccg agaatacaaa tccaatccaa aagaatgtgt gaactgtcct ctgctaaacc
    13561 aatgtacca
//
LOCUS       DAZULR010000061        13432 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.062, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000061 DAZULR010000000
VERSION     DAZULR010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13432
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.062"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..197
                     /locus_tag="ACG8ZV_002305"
     CDS             <1..197
                     /locus_tag="ACG8ZV_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997581.1"
                     /translation="WFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLIIAIIAVGLV
                     FNAAGVKDILLELFNRIIGA"
     gene            314..811
                     /locus_tag="ACG8ZV_002306"
     CDS             314..811
                     /locus_tag="ACG8ZV_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HFS4997582.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSISELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMSDVARYYIEETGALGEVPASLQNYIDYESYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            898..1290
                     /locus_tag="ACG8ZV_002307"
     CDS             898..1290
                     /locus_tag="ACG8ZV_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFS4997583.1"
                     /translation="MKKIRSYTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAV
                     MILGNLPPLSMIEGAFLKYFGIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRRKLTY
                     AGKKVTLGRNQPQEAITAVRSEFYGISN"
     gene            1274..3721
                     /locus_tag="ACG8ZV_002308"
     CDS             1274..3721
                     /locus_tag="ACG8ZV_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFS4997584.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSILSAQERSKNEVTGKLKTVAYDKIDQQTDALISM
                     IGENQVDYRFFIGFKLLLNDQEFSMKSLTVEAKNAFTDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYPLSKKKLEH
                     ETLIKTYDLIKPTRCLVEEKQRYLKIQQEDETAYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVNLTSDEKNKGLLDPYVIMKNTKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSDGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            3724..5907
                     /locus_tag="ACG8ZV_002309"
     CDS             3724..5907
                     /locus_tag="ACG8ZV_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HFS4997585.1"
                     /translation="MKPSILNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVTPSGLSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHALMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNMTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRM
                     MRKPRMLMHAHMHRLQRKLGRSVTALGAGSAIASATGKKGQSGSGSSASTQADHSRPN
                     GQEKSTLGKRIGQTIGTVADTKDRMVDTAGNLKEQVKDLPTNARYAVYQGKSKVTDNV
                     HDLTRSISQTKADKASGRKKQQEQRRKTIAERRSEMEQVKQKKQPASSVHERPATKQE
                     QSHDGQTSRQTTVQASYRESQQAKQERPTVKSDSSSLKTERQSNTVQERTVQKPVTST
                     APTDRASQRSITKERQSTVQRVPLQNTKSRPPIKTATIKKGSKKP"
     gene            5904..6905
                     /locus_tag="ACG8ZV_002310"
     CDS             5904..6905
                     /locus_tag="ACG8ZV_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HFS4997586.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDGGFSNIHYGGV
                     DVSAEVLAHKPMVEKVAKEYGIEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLGVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGDEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKFEGWKYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTRHIPLLEAKA
                     GDLVFFHSTYNAGSYITHIGIYLGDNRMFHAGDPIGYADLTSSYWQQHLVGAGRIKQ"
     gene            6920..7834
                     /locus_tag="ACG8ZV_002311"
     CDS             6920..7834
                     /locus_tag="ACG8ZV_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFS4997587.1"
                     /translation="MMKFGKNQNTEKQTPKEKKPRVYKVNPRKKVVIVLWVLLGLSFS
                     FAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWELNDKSIDNRIEN
                     LKAYLTEELQALNVDTVRKDIPVSSSVKGFQIWTVEADGDNQFDVTYSVDQLITEGEN
                     TKTVHSAYIVSVYVDSTGNMVLIKNPTITSIPKKSDYKPKAIESEGTVDSITTNEINE
                     FLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIYNRKDNQVTVSLTVEY
                     IDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            8148..8195
                     /locus_tag="ACG8ZV_002312"
                     /pseudo
     CDS             8148..8195
                     /locus_tag="ACG8ZV_002312"
                     /inference="COORDINATES: protein motif:HMM:NF011335.0"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            8211..10130
                     /gene="tet(M)"
                     /locus_tag="ACG8ZV_002313"
     CDS             8211..10130
                     /gene="tet(M)"
                     /locus_tag="ACG8ZV_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HFS4997588.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            10228..11601
                     /gene="tet(L)"
                     /locus_tag="ACG8ZV_002314"
     CDS             10228..11601
                     /gene="tet(L)"
                     /locus_tag="ACG8ZV_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008493 - tetracycline transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015904 - tetracycline transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HFS4997589.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT
                     SYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS
                     MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV
                     SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTS
                     FLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVY
                     KHSQRDF"
     gene            12165..13427
                     /gene="mobV"
                     /locus_tag="ACG8ZV_002315"
     CDS             12165..13427
                     /gene="mobV"
                     /locus_tag="ACG8ZV_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /protein_id="HFS4997590.1"
                     /translation="MSYAVCRMQKVKSAGLKGMQFHNQRERKSRTNDDIDHERTRENY
                     DLKNDKNIDYNERVKEIIESQKTGTRKTRKDAVLVNELLVTSDRDFFEQLDPGEQKRF
                     FEESYKLFSERYGKQNIAYATVHNDEQTPHMHLGVVPMRDGKLQGKNVFNRQELLWLQ
                     DKFPEHMKKQGFELKRGERGSDRKHIETAKFKKQTLEKEIDFLEKNLAVKKDEWTAYS
                     DKVKSDLEVPAKRHMKSVEVPTGEKSMFGLGKEIMKTEKKPTKNVVISERDYKNLVTA
                     ARDNDRLKQHVRNLMSTDMAREYKKLSKEHGQVKEKYSGLVERFNENVNDYNELLEEN
                     KSLKSKISDLKRDVSLIYESTKEFLKERTDGLKAFKNVFKGFVDKVKDKTAQFQEKHD
                     LEPKKNEFELTHNREVKKERSRDQGMSL"
BASE COUNT         4328 a         2335 c         2829 g         3940 t
ORIGIN      
        1 actggtttct atcaaacgct caatcactgg tgcttttagc aatcgttgtg attggcttgt
       61 atcttggctt caagcgtgag tttagcaaac tgattggctt tttaattatt gcgattattg
      121 cggttggctt agtcttcaac gctgctggag taaaagacat tttactagag ctattcaatc
      181 gcattattgg tgcttaaata aaaccgttct tttgtggaat ataagtggtt ttcttatgtt
      241 ccgcaaagga atggtacacc aaacgaagtg cggtagggat ttttgaatct ctacaaagaa
      301 aggacgtgaa tatatggacg atatgcaagt ctatattgcg aatttaggca aatacaatga
      361 gggcgaattg gtcggtgcgt ggtttacctt tcccattgac tttgaggaag tcaaagagaa
      421 aatcggcttg aatgatgaat atgaggaata cgccattcat gattacgagt taccctttac
      481 ggttgacgaa tacacttcta ttagcgaact caatcgccta tgggaaatgg tatcggagtt
      541 gccagaagaa ctacaatcgg agctatctgc tctgctcact catttttcaa gtattgaaga
      601 actaagcgaa catcaagaag atattatcat tcattccgat tgtgatgata tgtctgacgt
      661 ggcacgctac tacattgaag aaacgggtgc tttaggcgaa gtgccagcca gtcttcaaaa
      721 ctatattgat tatgaatcct atggtcggga tttagacctt tcgggaacgt ttatctcaac
      781 caatcacggg atttttgaaa tcgtctatta aatctgtcgg tacattctta ctggcagatt
      841 ttcttgttta cggggtagtc aaaagactat ccccattttt atgaaaggat tgattacatg
      901 aagaaaatac gaagctatac cagtatctgg tctgttgaga aagtgttgta ctccatcaat
      961 gactttagac ttccgtttcc cataaccttt acgcaaatga catggtttgt cgtgtcactc
     1021 tttgcagtta tgatacttgg caacttgccc cctctttcta tgatagaggg agcatttctc
     1081 aaatactttg ggattcctgt ggctttcaca tggtttatgt ctacaaaaac ctttgatggt
     1141 aaaaagcctt atggattttt gaagtctgtc attgcttatg cactgcgacg aaagctgacc
     1201 tatgcaggaa aaaaagtaac gcttggcaga aaccagccac aagaagccat tacagcagtt
     1261 aggagtgaat tttatggcat atccaattaa atatattgaa aacaatctgg tctggaataa
     1321 agatggggaa tgttacgctt actatgagct tgttccctac aattactcat ttctaagtcc
     1381 ggaacagaaa atacaagtac atgattcttt cagacagctt atcgcacaaa atcgtgatgg
     1441 caagattcat gctttacaaa tcagtacaga atccagcata ctttctgcac aagaacgttc
     1501 caaaaatgaa gtcactggaa agctcaaaac ggttgcctat gacaaaatcg accaacagac
     1561 agacgcttta atatccatga ttggcgaaaa tcaagtggac taccgtttct ttatcggttt
     1621 taagttgctt ctcaacgatc aggagttttc tatgaaaagt cttaccgttg aagcaaaaaa
     1681 tgcttttact gattttgtct atgatgtgaa ccataagctg atgggcgatt ttgttagtat
     1741 gagtaatgat gaaatcctgc gttttcagaa gatggaaaag cttttagaaa ataaaatctc
     1801 ccgtcgtttc aaaatccgaa gattagataa ggatgacttc ggctatctga ttgaacacct
     1861 ttacggacag acaggcactg cctatgaaga gtatgagtat cctctatcaa agaaaaagct
     1921 ggaacatgaa acactgatta aaacctatga cctcattaag cctactcgct gtctggtgga
     1981 agaaaaacag cgatatttga aaatccagca ggaagacgaa accgcctatg tagcttactt
     2041 taccatcaac agtattgtcg gcgaactgga cttcccgtcc tctgaaatct tctactacca
     2101 gcaacagcaa tttacctttc cgattgatac gtcaatgaat gtggaaattg tagcgaatcg
     2161 taaagcccta tctactgtcc gcaataaaaa gaaagaactg aaagacttgg ataaccacgc
     2221 ttggcaaagt gataatgaaa ccagctctaa tgtggcggaa gctctggaaa gtgtgaacga
     2281 gctggaaacc aatttagacc aaagcaagga atctatgtat aagctgtcct atgttgtaag
     2341 ggtatcagca aatgaccttg acgaacttaa acgtcgttgt aatgaagtga aagatttcta
     2401 tgatgatttg agcgtgaaac tggtacgacc ttttggggat atgctgggct tacatgaaga
     2461 atttttacct gccagcaaaa gatatatgaa tgactatatt caatacgtga cctctgattt
     2521 cctcgctggt ttaggttttg gtgctactca aatgctgggt gaaaatgagg ggatttatgt
     2581 tggctacagc ttagatactg gacgcaatgt ctatctgaaa cctgctcttg ccagtcaagg
     2641 ggttaagggt tcagtaacca atgcgttagc gtctgccttt gtcggttcgc tgggtggtgg
     2701 taaatccttt gcgaataacc ttatcgtcta ttatgcagtg ctttatgggg cacaagcagt
     2761 gattgtagac ccaaaagcag aacgtggcag atggaaagaa accttgccag agatttccca
     2821 tgaaatcaat atcgtcaatc tgacttctga tgagaaaaac aaaggcttac ttgaccctta
     2881 tgtaattatg aaaaatacca aagattctga atcactggct attgatattt tgacattcct
     2941 tacggggatt tcctctcgtg atggggaacg cttcccaatc cttagaaaag ccattcgtgc
     3001 agtaaccaat agtgaagtgc gagggttgat gaaagtgatt gaagaattac gggttgagaa
     3061 tacgccacta agtaccagca tagccgacca tatcgaaagt tttacagact atgactttgc
     3121 ccatctgctt tttagtgatg gttatgtaga gcagtctatc agccttgaaa aacaactgaa
     3181 cattatacag gttgccgact tggtacttcc tgacaaggaa acttcctttg aggaatatac
     3241 cacaatggag ttactatcgg tagcaatgct gattgtcatt agtacctttg cgttggactt
     3301 tatccataca gaccgaagta ttttcaagat tgtagactta gacgaagcat ggagcttctt
     3361 acaggtggca caagggaaaa cactatctat gaagctggtt cgtgctggtc gtgctatgaa
     3421 cgctggggta tatttcgtga cccaaaatac agatgacctc ttagatgaaa aactgaaaaa
     3481 taacctcggc ttaaaatttg cctttcgttc cactgacctt aacgagatta aaaaaaccct
     3541 tgcctttttt ggtgtagacc cagaggacga aaacaatcag aagcgattgc gtgatttgga
     3601 aaacgggcaa tgccttatca gtgatttata tggtcgtgtc ggtgtgatac agttccaccc
     3661 tgtatttgaa gaactgctcc atgcctttga taccagacca cctgtgcgaa aagaggtgta
     3721 aatgtgaaac catcaatatt aaacagaata aaatcaaact ggacgctgaa acgtctaggt
     3781 aaagtggcaa tgacagtggc tttcacactt gtgattgcca tttttctttt agccatgctg
     3841 ggaacggtgg ttcaagctgc gggcttggta gatgatacgg tcaatgtggc aaatgaatac
     3901 agccgatacc cacttgaaaa ctatcaactg gatttttatg tggataatag ctggggctgg
     3961 ctaccgtgga actggtcgga cggaattgga aaacaagtca tgtatggact atatgccatt
     4021 accaatttta tttggacaat cagtctttat gtttccaatg cgacgggtta cttagtacag
     4081 gaagcctatt ccttagactt catttccgct acagcagatt ccattggcaa gaatatgcag
     4141 acccttgcag gggttacgcc tagtggacta tcaacagagg gtttctatgt tggattcctt
     4201 ttactcttga ttttggttct tggggtttat gttgcctata caggactgat aaagagagaa
     4261 accacaaagg caattcatgc cctcatgaat tttgtgctgg tttttatcct atcggcttcc
     4321 tttattgcct acgctcccga ctacattaaa aaaatcaatg acttttcatc agacatcagc
     4381 aacgctagtt tgtcactggg tacaaaaatt gtcatgcccc attcagatag tcaaggcaag
     4441 gacagtgtgg acttgatacg tgacagccta ttttccatac aggttcagca accgtggcta
     4501 ctgcttcaat ataacagttc agacattgaa agtattggta ttgaccgtgt ggaaagcctg
     4561 ctctcaacca gtccagattc caacaatggg gaagacagag aaaaaattgt tgcggaagaa
     4621 attgaagata gaagcaatac caatatgacg attacaaaga cgattaaccg tttaggtaca
     4681 gtcttcttcc tatttgtctt caatattggg atttccatat ttgtattcct attaacagga
     4741 atcatgattt tctcgcaggt actttttatc atctatgcta tgtttctgcc tgtgagcttt
     4801 attttaagca tgattccatc atttgatggt atgtcaaaac gagccataac aaagctcttt
     4861 aataccattt tgacacgagc tggaatcaca ttgattatta cgacagcatt tagtatttca
     4921 accatgctct ataccttatc ggctggttat ccgttctttt tgattgcttt tctacagatt
     4981 gtgacctttg caggaatcta ctttaagctg ggcgatttaa tgagtatgtt ttctctacag
     5041 agtaacgatt ctcaaagtgt gggaagtcgt atgatgagaa aacctcgtat gcttatgcac
     5101 gctcacatgc accgtctaca gcggaaactt ggacgctccg tgactgcttt aggggctggg
     5161 tctgccattg ccagtgctac gggtaaaaaa ggacagtcgg gttcgggaag ttctgcgagt
     5221 acacaagcag atcactctcg accaaacggg caggaaaaat caacactagg aaagcgtatc
     5281 ggtcaaacca tcggtacagt agctgatacc aaagacagaa tggtagatac tgctggtaat
     5341 ttgaaagaac aggttaagga tttgccgacc aatgcaagat atgcagtata tcaaggaaaa
     5401 tctaaagtga cggataatgt ccatgattta accagaagta tttctcaaac caaagcggat
     5461 aaagccagtg gacgcaagaa acagcaggaa caaagacgga aaaccattgc ggagcgtcgc
     5521 tctgaaatgg aacaggtcaa acagaaaaaa cagccagctt cttccgttca tgaaagacca
     5581 gccactaagc aagaacaatc tcatgatgga cagacttcaa ggcaaacaac tgtacaggct
     5641 tcctataggg aatctcaaca agccaaacaa gagcgtccaa cagttaagtc cgattcttca
     5701 agtttaaaaa cggaacgtca aagtaataca gttcaagaaa gaacggttca aaagccagta
     5761 acttcaactg caccaacaga tagagcttca caacgttcaa tcacaaaaga acgtcagtct
     5821 actgttcaaa gagtaccact acaaaataca aaaagtagac caccaatcaa aaccgccacc
     5881 attaagaaag gcagtaagaa accatgaagc tgaaaacttt agtgattggt ggttcgggat
     5941 tattcttgat ggtcttctca ctgcttctgt ttgtcgccat tttattttca gatgaacaag
     6001 atggcggttt ttccaacatt cactatggcg gtgtggatgt ttccgcagaa gtgctggctc
     6061 ataagcctat ggtagaaaaa gttgccaaag aatatggaat tgaagaatac gtcaatatac
     6121 ttcttgcgat tatacaggtg gaatcgggtg gtacagcaga agatgttatg cagtcctcgg
     6181 aatccctcgg tcttccacct aattcattga gtacagaaga atccattaag caaggtgtga
     6241 agtatttcag tgagttatta gccagtagcg aaaggcttgg tgtagattta gaatcggtta
     6301 tccagtccta caattatggt ggtggtttct taggatatgt ggctaatcgt gggaataaat
     6361 atacctttga actggctcaa agtttctcaa aagagtattc gggtgacgaa aaagtgtctt
     6421 accccaatcc catagccata cctatcaatg ggggctggcg atacaattac gggaatatgt
     6481 tttatgtgca actggtaacg cagtatcttg tcacaacaga gtttgatgat gatacagtac
     6541 aagccatcat ggacgaagct ctgaaatttg aaggctggaa gtatgtctat ggcggagctt
     6601 ccccgactac ctcttttgat tgtagcggac tgacacaatg gacgtatgga aaagctggaa
     6661 tcaacttacc acgaacagca caacagcaat atgatgtaac ccggcatatc ccattattgg
     6721 aagcaaaagc cggcgatttg gttttctttc attctaccta taacgctggc tcttatatta
     6781 ctcatatcgg gatttattta ggcgataacc gtatgtttca tgcaggcgac cctatcggtt
     6841 atgccgactt aacaagctct tactggcaac agcatttagt gggagcagga cgaatcaaac
     6901 aataagaaag gacgattcaa tgatgaaatt cggaaaaaat cagaatacag aaaaacagac
     6961 accaaaggaa aagaaacctc gtgtctataa ggtcaatcct cgtaaaaagg ttgtgattgt
     7021 cctatgggta cttttaggac ttagtttcag ctttgcgata ttcaagcact ttacagccat
     7081 tgatacccat accattcatg aaaccaccat catagaaaag gaatatgtcg atactcatca
     7141 tgtggaaaat tttgtagaga actttgcgaa agtctactat tcatgggaac taaacgacaa
     7201 gtccattgat aatcgcatag aaaacctgaa agcatatctg acagaggaac ttcaagctct
     7261 gaatgtcgat acagttcgta aagatattcc tgtatcgtct tctgtaaaag gatttcagat
     7321 atggacggta gaagcagatg gcgacaatca atttgatgta acctacagtg tagaccaact
     7381 cattacagag ggggaaaata caaagaccgt ccactctgct tatatagtga gtgtctatgt
     7441 agacagtact ggaaatatgg tcctcattaa gaatccgacc attactagca taccaaagaa
     7501 atcagactat aaaccaaaag ctattgaaag tgagggtacg gttgattcca ttacaaccaa
     7561 tgaaatcaat gagtttttaa cgacgttctt caagctctat cctacagcga cagccagtga
     7621 actttcctac tatgtgaatg acgggatatt aaaaccaatc ggaaaagagt acatctttca
     7681 agaactggta aatcctattt acaatcgtaa ggataatcaa gtcacggtat cgctgacagt
     7741 ggagtatatc gaccagcaga ccaaagcaac gcaggtatct caatttgatt tggtacttga
     7801 aaagaacggg agtaattgga agattataga ataacaaata ttggtacatt attacagcta
     7861 ttttgtaatc acgtactctc tttgataaaa aattggagat tcctttacaa atatgctctt
     7921 acgtgctatt atttaagtat ctatttaaaa ggagttaata aatatgcggc aaggtattct
     7981 taaataaact gtcaatttga tagtgggaac aaataattgg atgtcctttt ttaggagggc
     8041 ttagtttttt gcacccagtt taagaatacc tttatcatgt gattctaaag tatccggaga
     8101 atatctgtat gctttgtatg cctatggtta tgcataaaaa tcccagtgat aagagtattt
     8161 atcactggga tttttatgcc cttttgggct tttgaatgga ggaaaatcac atgaaaatta
     8221 ttaatattgg agttttagct catgttgatg cgggaaaaac taccttaaca gaaagcttat
     8281 tatataacag tggagcgatt acagaattag gaagcgtgga caaaggtaca acgaggacgg
     8341 ataatacgct tttagaacgt cagagaggaa ttacaattca gacaggaata acctcttttc
     8401 agtgggaaaa tacgaaggtg aacatcatag acacgccagg acatatggat ttcttagcag
     8461 aagtatatcg ttcattatca gttttagatg gggcaattct actgatttct gcaaaagatg
     8521 gcgtacaagc acaaactcgt atattatttc atgcacttag gaaaatgggg attcccacaa
     8581 tcttttttat caataagatt gaccaaaatg gaattgattt atcaacggtt tatcaggata
     8641 ttaaagagaa actttctgcc gaaattgtaa tcaaacagaa ggtagaactg tatcctaata
     8701 tgtgtgtgac gaactttacc gaatctgaac aatgggatac ggtaatagag ggaaacgatg
     8761 accttttaga gaaatatatg tccggtaaat cattagaagc attggaactc gaacaagagg
     8821 aaagcataag atttcagaat tgctccttgt accctgttta tcatggaagc gcaaaaagca
     8881 acatagggat tgagcagctt atagaagtga taacgaataa attttattca tcaacataca
     8941 gaaagaagtc tgaactttgc ggaaatgtct tcaaaattga atattcggaa gaaagacaac
     9001 gtcttgcata tgtacgcctt tatggcggaa tcctgcattt gcgggattcg gttagaatat
     9061 cggaaaagga aaaaataaaa attacagaaa tgtatacttc aataaatggt gaattatgta
     9121 aaattgataa ggcttattcc ggggaaattg ttattttgca aaatgagttt ttgaagctaa
     9181 atagtgttct tggagataca aagctattgc cacagagaga gagaattgaa aatccgctcc
     9241 ctctgctgca aacaactgtt gaaccgagca aacctcaaca aagggaaatg ttacttgatg
     9301 cacttttaga aatctccgac agtgacccgc ttctacaata ttatgtggat tctacgacac
     9361 atgaaattat actttctttc ttagggaaag tacaaatgga agtgattagt gcactgttgc
     9421 aagaaaagta tcatgtggag atagaactaa aagagcctac agtcatttat atggagagac
     9481 cgttaaaaaa tgcagaatat accattcaca tcgaagtgcc gccaaatcct ttctgggctt
     9541 ccattggttt atctgtatca ccgcttccgt tgggaagtgg aatgcagtat gagagctcgg
     9601 tttctcttgg atacttaaat caatcatttc aaaatgcagt tatggaaggg atacgctatg
     9661 gttgcgaaca aggattatat ggttggaatg tgacggattg taaaatctgt tttaagtatg
     9721 gcttatacta tagccctgtt agtaccccag cagattttcg gatgcttgct cctattgtat
     9781 tggaacaagt cttaaaaaaa gctggaacag aattgttaga gccatatctt agttttaaaa
     9841 tttatgcgcc acaggaatat ctttcacgag catacaacga tgctcctaaa tattgtgcga
     9901 acatcgtaga cactcaattg aaaaataatg aggtcattct tagtggagaa atccctgctc
     9961 ggtgtattca agaatatcgt agtgatttaa ctttctttac aaatggacgt agtgtttgtt
    10021 taacagagtt aaaagggtac catgttacta ccggtgaacc tgtttgccag ccccgtcgtc
    10081 caaatagtcg gatagataaa gtacgatata tgttcaataa aataacttag tgtattttat
    10141 gttgttatat aaatatggtt tcttgttaaa taagatgaaa tattttttaa taaagatttg
    10201 aattaaagtg taaaggagga attaattatg aagtgtaatg aatgtaacag ggttaaatac
    10261 aaccaaattt taatttggct ttgcgtttta tcttttttta gcgtattaaa tgaaatggtt
    10321 ttgaacgtct cattacctga tattgcaaat gattttaata aaccacctgc gagtacaaac
    10381 tgggtgaaca cagcctttat gttaaccttt tccattggaa cagctgtata tggaaagcta
    10441 tctgatcaat taggcatcaa aaggttactc ctatttggaa ttataataaa ttgtttcggg
    10501 tcggtaattg ggtttgttgg ccattctttc ttttccttac ttattatggc tcgttttatt
    10561 caaggggctg gtgcagctgc atttccagca ctcgtaatgg ttgtagttgc gcgctatatt
    10621 ccaaaggaaa ataggggtaa agcatttggt cttattggat cgatagtagc catgggagaa
    10681 ggagtcggtc cagcgattgg tggaatgata gcccattata ttcattggtc ctatcttcta
    10741 ctcattccta tgataacaat tatcactgtt ccgtttctta tgaaattatt aaagaaagaa
    10801 gtaaggataa aaggtcattt tgatatcaaa ggaattatac taatgtctgt aggcattgta
    10861 ttttttatgt tgtttacaac atcatatagc atttcttttc ttatcgttag cgtgctgtca
    10921 ttcctgatat ttgtaaaaca tatcaggaaa gtaacagatc cttttgttga tcccggatta
    10981 gggaaaaata taccttttat gattggagtt ctttgtgggg gaattatatt tggaacagta
    11041 gcagggtttg tctctatggt tccttatatg atgaaagatg ttcaccagct aagtactgcc
    11101 gaaatcggaa gtgtaattat tttccctgga acaatgagtg tcattatttt cggctacatt
    11161 ggtgggatac ttgttgatag aagaggtcct ttatacgtgt taaacatcgg agttacattt
    11221 ctttctgtta gctttttaac tgcttccttt cttttagaaa caacatcatg gttcatgaca
    11281 attataatcg tatttgtttt aggtgggctt tcgttcacca aaacagttat atcaacaatt
    11341 gtttcaagta gcttgaaaca gcaggaagct ggtgctggaa tgagtttgct taactttacc
    11401 agctttttat cagagggaac aggtattgca attgtaggtg gtttattatc cataccctta
    11461 cttgatcaaa ggttgttacc tatggaagtt gatcagtcaa cttatctgta tagtaatttg
    11521 ttattacttt tttcaggaat cattgtcatt agttggctgg ttaccttgaa tgtatataaa
    11581 cattctcaaa gggatttcta aatcgttaag ggatcaactt tgggagagag ttcaaaattg
    11641 atcctttttt tataacagga attcaaatct ttttgttcca ttaaagggcg cgattgctga
    11701 ataaaagata cgagagacct ctcttgtatc ttttttattt tgagtggttt tgtccgttac
    11761 actagaaaac cgaaagacaa taaaaatttt attcttgctg agtctggctt tcggtaagct
    11821 agacaaaacg gacaaaataa aaattggcaa gggtttaaag gtggagattt tttgagtgat
    11881 cttctcaaaa aatactacct gtcccttgct gatttttaaa cgagcacgag agcaaaaccc
    11941 ccctttgctg aggtggcaga gggcaggttt ttttgtttct tttttctcgt aaaaaaaaga
    12001 aaggtcttaa aggttttatg gttttggtcg gcactgccga cagcctcgca gagcacacac
    12061 tttatgaata taaagtatag tgtgttatac tttacttgga agtggttgcc ggaaagagcg
    12121 aaaatgcctc acatttgtgc cacctaaaaa ggagcgattt acatatgagt tatgcagttt
    12181 gtagaatgca aaaagtgaaa tcagctggac taaaaggcat gcaatttcat aatcaaagag
    12241 agcgaaaaag tagaacgaat gatgatattg accatgagcg aacacgtgaa aattatgatt
    12301 tgaaaaatga taaaaatatt gattacaacg aacgtgtcaa agaaattatt gaatcacaaa
    12361 aaacaggtac aagaaaaacg aggaaagatg ctgttcttgt aaatgagttg ctagtaacat
    12421 ctgaccgaga tttttttgag caactggatc caggagaaca aaaacgattt tttgaggaaa
    12481 gttataaatt attttccgaa cgatatggca agcaaaatat tgcttatgca acagttcata
    12541 atgatgagca aacccctcac atgcatttag gtgttgtgcc tatgcgtgat ggaaaactgc
    12601 aaggaaaaaa tgtgtttaat cgtcaagaac tgttatggct acaagataaa ttccccgagc
    12661 atatgaaaaa acagggtttt gagttgaagc gtggtgaacg tggctctgac cgtaaacata
    12721 ttgagacagc taaatttaaa aaacaaactt tggaaaaaga gattgatttt ctagaaaaaa
    12781 atttagcagt taaaaaagat gaatggactg cttatagcga taaagttaaa tcagatttag
    12841 aagtaccagc gaaacgacac atgaaaagtg ttgaagtgcc aacgggtgaa aagtccatgt
    12901 ttggtttggg aaaagaaata atgaaaacag aaaagaaacc aaccaaaaat gttgttatat
    12961 cggagcgtga ttataaaaac ttagtgactg ctgcgagaga taacgatagg ttaaaacagc
    13021 atgttagaaa tctcatgagt actgatatgg cgagagaata taaaaaatta agtaaagaac
    13081 atgggcaagt taaagaaaaa tatagtggtc ttgtagagcg atttaatgaa aatgtaaatg
    13141 attataatga gttgcttgaa gaaaacaagt ctttaaagtc taaaataagc gatttaaagc
    13201 gtgatgtgag tttaatctat gaaagcacta aggaattcct taaggaacgt acagacggct
    13261 taaaagcctt taaaaacgtt tttaaggggt ttgtagacaa ggtaaaggat aaaacagcac
    13321 aattccaaga aaaacacgat ttagaaccta aaaagaacga atttgaacta actcataacc
    13381 gagaggtaaa aaaagaacga agtcgagatc agggaatgag tttataaaat aa
//
LOCUS       DAZULR010000062        13306 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.063, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000062 DAZULR010000000
VERSION     DAZULR010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13306)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13306)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13306
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.063"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..254)
                     /locus_tag="ACG8ZV_002316"
     CDS             complement(<1..254)
                     /locus_tag="ACG8ZV_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail adaptor protein"
                     /protein_id="HFS4997591.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQY"
     gene            complement(244..555)
                     /locus_tag="ACG8ZV_002317"
     CDS             complement(244..555)
                     /locus_tag="ACG8ZV_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997592.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            complement(552..1427)
                     /locus_tag="ACG8ZV_002318"
     CDS             complement(552..1427)
                     /locus_tag="ACG8ZV_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997593.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIQIWTAEMWAQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            complement(1437..2597)
                     /locus_tag="ACG8ZV_002319"
     CDS             complement(1437..2597)
                     /locus_tag="ACG8ZV_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFS4997594.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            complement(2597..3283)
                     /locus_tag="ACG8ZV_002320"
     CDS             complement(2597..3283)
                     /locus_tag="ACG8ZV_002320"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0046797 - viral procapsid maturation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head maturation protease, ClpP-related"
                     /protein_id="HFS4997595.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            complement(3246..4424)
                     /locus_tag="ACG8ZV_002321"
     CDS             complement(3246..4424)
                     /locus_tag="ACG8ZV_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFS4997596.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            complement(4444..6138)
                     /locus_tag="ACG8ZV_002322"
     CDS             complement(4444..6138)
                     /locus_tag="ACG8ZV_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HFS4997597.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            complement(6116..6430)
                     /locus_tag="ACG8ZV_002323"
     CDS             complement(6116..6430)
                     /locus_tag="ACG8ZV_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HFS4997598.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            complement(6533..6814)
                     /locus_tag="ACG8ZV_002324"
     CDS             complement(6533..6814)
                     /locus_tag="ACG8ZV_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997599.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            complement(6819..7163)
                     /locus_tag="ACG8ZV_002325"
     CDS             complement(6819..7163)
                     /locus_tag="ACG8ZV_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="HFS4997600.1"
                     /translation="MTEEFYRWLLQLTREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            complement(7189..7356)
                     /locus_tag="ACG8ZV_002326"
     CDS             complement(7189..7356)
                     /locus_tag="ACG8ZV_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HFS4997601.1"
                     /translation="MYRPQYLEQKYEVITVHKGNGEKVYEYRRPIKSDTYKRKENNEV
                     IPLYGKRIAKH"
     gene            complement(7552..7716)
                     /locus_tag="ACG8ZV_002327"
     CDS             complement(7552..7716)
                     /locus_tag="ACG8ZV_002327"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997602.1"
                     /translation="MPATLNAYDGYDYRKKIVKKLYGATYGNVVSVLSVHHQASVTVA
                     EVEDAAVNGE"
     gene            8212..8487
                     /locus_tag="ACG8ZV_002328"
     CDS             8212..8487
                     /locus_tag="ACG8ZV_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997603.1"
                     /translation="MYKPYMISYDLNNPGQKYDKVFEIIKEFGAYIKLQKSFWLVKTN
                     LNPNQMCEKLNTVLDNNDSLFICELQKNYQGRATEENWKFINEHIFS"
     gene            complement(8484..8636)
                     /locus_tag="ACG8ZV_002329"
     CDS             complement(8484..8636)
                     /locus_tag="ACG8ZV_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997604.1"
                     /translation="MKLSVEGTPEEIQELLQAIGSSKEQKVSVSNSDIDGICNCLNRE
                     KISNPY"
     gene            complement(8945..9358)
                     /locus_tag="ACG8ZV_002330"
     CDS             complement(8945..9358)
                     /locus_tag="ACG8ZV_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family phage packaging/lysis
                     transcriptional regulator"
                     /protein_id="HFS4997605.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIETERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGKIIAYK"
     gene            complement(9435..9731)
                     /locus_tag="ACG8ZV_002331"
     CDS             complement(9435..9731)
                     /locus_tag="ACG8ZV_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997606.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKSKFKVGDMVRCEA
                     EEFVYPFRGYVKKILSNSAIIRIENTMKCDRSTAKHKHYLAVARLVDMEVIKSK"
     gene            complement(9728..10285)
                     /locus_tag="ACG8ZV_002332"
     CDS             complement(9728..10285)
                     /locus_tag="ACG8ZV_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HFS4997607.1"
                     /translation="MNKQEAIKKLESIKAIGNDAIAACYNESINSGITLMKKIDEPQK
                     PVIPQLVAGWLEKSTDPFTKAEKIAYLIKSKDGDSYYFCDWFVRDGIVTQEQGEELLA
                     WATRQSYETLLSLYNGYEVEKEPLWAIKNADGNYLTKCALWGKDGVNYSFECNPSHRL
                     LFTDKATADAAALLVNGTVEEVVER"
     gene            complement(10282..10701)
                     /locus_tag="ACG8ZV_002333"
     CDS             complement(10282..10701)
                     /locus_tag="ACG8ZV_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HFS4997608.1"
                     /translation="MIPKFRAWDKRKNVMRDVAVLHFTKNGKTNFIEYWINPTELKSY
                     HVRNIDLMQSTGMKDKNGVDIFEGDIVLVSVRNGFDYLDNKVCIVKNSIDYSGLVCAT
                     VDEDLEYQIFNTELFEEYTYEVTGNIYENSELLEEQR"
     gene            complement(10698..10943)
                     /locus_tag="ACG8ZV_002334"
     CDS             complement(10698..10943)
                     /locus_tag="ACG8ZV_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997609.1"
                     /translation="MIKKLVQFSMDLYDIESGATLSVESDHLIINFGGKRQIILWVVD
                     DVLFPEIVHDFEESKAVEFEIVKKVMELIEKYEEDSE"
     gene            complement(10903..11259)
                     /locus_tag="ACG8ZV_002335"
     CDS             complement(10903..11259)
                     /locus_tag="ACG8ZV_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HFS4997610.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILEEYLR
                     RTANDKKTRSIQHGFI"
     gene            complement(11259..11564)
                     /locus_tag="ACG8ZV_002336"
     CDS             complement(11259..11564)
                     /locus_tag="ACG8ZV_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997611.1"
                     /translation="MSVDKKAAMKRIAELTKSESWQEDKEIVAEVQKLGKSMWTEKPK
                     RRTPRKIAIWHDDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEER"
     gene            complement(11561..11722)
                     /locus_tag="ACG8ZV_002337"
     CDS             complement(11561..11722)
                     /locus_tag="ACG8ZV_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HFS4997612.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIHRLEE"
     gene            complement(11719..12021)
                     /locus_tag="ACG8ZV_002338"
     CDS             complement(11719..12021)
                     /locus_tag="ACG8ZV_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997613.1"
                     /translation="MDKKAAMQRIIELTYSEDWQNDKEAASEVMRLGRAMWADKSNKP
                     RPRKIAIWHGDKLLVIGTAEQLASLTGLHEKIVRKRARCGYTDAKKRTFRYVEESS"
     gene            complement(12014..12178)
                     /locus_tag="ACG8ZV_002339"
     CDS             complement(12014..12178)
                     /locus_tag="ACG8ZV_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997614.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            complement(12183..12452)
                     /locus_tag="ACG8ZV_002340"
     CDS             complement(12183..12452)
                     /locus_tag="ACG8ZV_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997615.1"
                     /translation="MKIDYLELINEIAKYKTGEEIEILRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDTTQLRNLAYTKLLFVDCVKGLQKHLNELEQV"
     gene            complement(12464..>13306)
                     /locus_tag="ACG8ZV_002341"
     CDS             complement(12464..>13306)
                     /locus_tag="ACG8ZV_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HFS4997616.1"
                     /translation="NKRYYYLKLKENFFDSDEMVLLESMPDGYIYSNILLKLYLRSLK
                     HEGKLMFNDRIPFNSTMLATITRHSVGVVEKAVQIFRDLQLIEVLDNGAIYMSDIQSF
                     IGKSSTEADRKRKYRKEIEEAKQNLITSGQMSDKCPDKTTPELEIELEKDIELEKDIE
                     NVTPSKKSKAKPVRHKYGEYKNVLLSDEQMEKLKIEFPNDYQERIERLSEYCESSGKT
                     YKNYLATIRSWARKEKSESKNASSGYKRTGRREKLPEWAIDQEAYLKKKALERANRQS
                     KAPF"
BASE COUNT         3691 a         2852 c         1960 g         4803 t
ORIGIN      
        1 aaatattgat ctttattaaa tttcttggcg attggatgaa atggagtctt tactttctta
       61 gttaatttcg atcccatcgc atccatagct gttatatcac tatctctcat ggaaagattt
      121 ctaaatttta aagaagtgat ttctgtatct tctacaccaa tcttttttcc tagttcattt
      181 cttttggtag tttgcgtcaa aatctttaac caaccatcgt tgaatgtttc ttcgagtcta
      241 cgattattcg ccattcacat cacctgcaat atattcttgt agcgcataat gttgaatgaa
      301 acctaataac tcactagcga aattttgttc aaactcatct aaagcacgat tccagtcgta
      361 tctacatctt tcgattagca atccgtattc taagctttca ggagaaaaag aaagtgttgt
      421 actcacttta ctttgaagat aaacagcatt tttagctatc atctttttaa ttgactcatc
      481 ttcttcgttc caggtaacgt aaatattatc cttcacagct attagcaatt cttcagtcac
      541 ttgttcaggc gtcatctaac caccgcctta attgctttaa catatgcgta agagcatttt
      601 ttcttgttta caaatgataa atcttcatca aaaggcgtag aagtcacgta tctccctttg
      661 aaaaataaat cttcatcgtt tgttgttact ccagcattgt gtaagatttt tacttcttta
      721 actttttcta ttggatcagt agcaaaacaa aagtctaatt cctcgtgaac tttaggacca
      781 atattgaaat acatcatgtt ccaaagctgt gcccacatct cggctgtcca gatttgtata
      841 tttgtttttt gccctctaag gtagcgatat agccgattag aatccagata aacctttttc
      901 caataattcg ctttaggacg gttaataacc cactgtgcgc ctcctgaatt agtgtttata
      961 gtttccaaag attctactgt aacatttaca atgtttgcca tatcttttag aatattttct
     1021 ccgttttcac agcttctaat ataatcaaga cttagataac tacagcagtc gctacaatac
     1081 caaacatcat ctttagaagg caatttgcgc aaattaattc ttttattgaa aatgacatcc
     1141 gaatcgatat agaaatatcg gtcgtcctca cgcgaatgat cttcttctaa atatttccac
     1201 cataaatatg gtttaatcga aggaatatac tctttgtcgt cccgcagatc atcgtacaca
     1261 tgaacttcaa caccatattc cttctcaaaa aaaataggaa tctgatcatc gtgtctgctg
     1321 aaaagcaata cgatatcttt gattcctagt ttcttcagat tagttaaaca aacttcaagc
     1381 tcccatttaa accgattgat tgccggctga caaagaatat acttcattct gatcacctac
     1441 gcttgtgttg tagttgttgt ggttgttggt tttgtagttg tagtagtagt tcccaaagcg
     1501 ctaatatcta atacaatgaa actatcgtta cgtttaggtt gaccgtttgc atattgttta
     1561 gctagataaa tgcgttcgtc ttcaacaaaa tggtattcat ctgaagcttc aatttttagt
     1621 gtagatccta cacccatgaa gtaatctgag gctaccccaa taactgcttt tccttctggc
     1681 acagccgttg actgcaaatc tgaaactggt actggcaata cttgtacgta ttctccatta
     1741 gcagttagta cagtcttagc tgggaatact ttagaccagt aatcagttgg attcacaatt
     1801 aggaccacat cagaaggatt cacattacga taaatcggat cattcacacc ttcgatattg
     1861 aattttgata gtcgcgccat caaaccgccc atagttacag catctaaagc tgtaataggt
     1921 tctgcttttt tttcagcata ttctccgcta gtttgtttgc tcatgtcacg catcattccg
     1981 actggcatat ctttaccagt accatcaaca attgcttgtt ctaatgcaat tctcaatgat
     2041 tctactaaaa cagtacggac ataacgatct aaccatactg gacctaaatc aagcattgcc
     2101 ttacatacag gaatataacc tgatagcttg aactgcttca tgttaattac atcaaagcca
     2161 ttatctaaaa cttttttaac agcttcgcaa agtttacccc accatgctgg attgactcca
     2221 cgtgacacaa tccattctgt tacaccagtt gtgttaacaa aagtaatttt ttgcaatagt
     2281 ggatgagatt gttctaaatc ttcaaataca cgttcaaata cagtagctgg cactaattct
     2341 tcgacccctg caaaaccttc gtttttcact acttcgttat agaattttgt ttcttgtgta
     2401 gttaatacac gctgaccacg gttcattaat actaattgat cttgattttt tgctgttgct
     2461 tcttctaaaa ttttatcctg aatttcctta gataagctta ccatagctgc gctaaaagat
     2521 tcttcgttac catctttaaa agctttcatc aattggtcgc ttgcagctgt tacacctttt
     2581 aaatttttaa ctgtcattat tttacatctc cttgtccaaa tgttttattt aatgctgctg
     2641 taaatgcagc aattttttct gctctttttt ctttaacgtc attcaaaatt tcttcaacgc
     2701 tttgttcttt tttagcttca gtacctgagc tattttctgc atcgataatt tcatcgacca
     2761 atccataact caaagctgtt tctgcatcca taaacgattc tttttcaaga agttcttgca
     2821 atgcttcatc tgtgccattg aatcgtgttt tatatgaagc ctttaccgat ttatcaattg
     2881 attccagttg gtcagcaatc gtacggaagt catcgacatt tccttctccg tatgtggaag
     2941 cgcggtgaat catcaattgt gcattgttgt agatttttat agtatcgcca gccattgcga
     3001 taattgaagc agcactagcg gctaagccgt taatcacaac gttaactttt gctttatttg
     3061 acttaagtaa gttcccaata gcaatccctt gaaatacgtc tccaccgttt gaattaatta
     3121 ctacttcaat ttcttcttga tcacctagac tatccaaaat atttttgatt cccttgtcag
     3181 tattcccttc aaagaaccaa ctagaaccaa taaatccctg aataaaaatt tgcggtactg
     3241 cgccttcatt ctttactgct agaaatgttt tcattgtcgt cattcgcctc acctcctttc
     3301 gatacttgtt gattgttttt agttataaat atttcatctg ccatcgcctt atcagagcga
     3361 tcatttccaa cgcgttctct tccttcgttg attgtaaata ctccatttct aatgcctaca
     3421 tcaatagcgt caaccaaatc tttgaagcta gtaatcttga tcatagttgt atccacacgt
     3481 acaaaattcc ctgacaagta ttcttctact tcatagagac tagcgttaaa cgcatcctga
     3541 ataagttcag caatcggtat gatttcgaac attaaaaaag cgtccacttg atccgataac
     3601 ccactcatgt ctccctttag taggtttttc ggaacgtgaa acgctgctgc tgtcatctca
     3661 aagatgtcgt ctattaagtt ttttatatct cttgaattgc tttggaagtt tccgctgaaa
     3721 tcttctaatg tgtactcatt ttgtaattga aataccgcac ctgcattatc agcttccata
     3781 aaagccttaa attgtgatgt catcatttta ttgatttgat cttgtgttgt attgtcttgc
     3841 ggtcggaata aattcccttt cagtacgtat ctacgagcgt tagagcgctt gtaaacattc
     3901 atggcactag aaatgagttt cccatacgct tgataatacg catcgactag ttgcctaatt
     3961 tgttgatctg cgtattttat atagataaca tcactttcta gaaattctct atcaaggact
     4021 atgttgttaa tttgcacttg agaaaacaca tcatctttca atgcatattc tgtgacatcc
     4081 caactatccg caataaatat ttcgctagaa ttattagacg gagaaacgat caatacttca
     4141 ttgtagaata ttaatctcct gatcagtttt tttctaaatt ctgttgcatt atttttctta
     4201 ttaggagcta cattcagcct atagtaaaga tcattctttt tattttttcc atcttcatat
     4261 gacttgaatt ccgctttact catcgcattt gcaatcaaat caatacaagt ttcaatcgca
     4321 aattttcgat acacaaaatc aacttgcaat ttacaaaagt attcttctaa aggaaccgtt
     4381 gctttttttg tgaagtatcc taccgccttt tgaaaaatcc ccactttctc acctcctttc
     4441 aagttagaat actagaggag taaatccagt tcctgtattt tctactgagc tatttgtgac
     4501 tgttacagga gcagaatcat aaatatcatc taaaaaattc aaaccatgaa ggaatgaaaa
     4561 aaagccatcc gtttttctag tttcaggttc tattttttca tagcgtatat ttccattaga
     4621 aatatgctct tcatatacat tcatgcaata ccaacgcata atcgcatcgt caccaaaaaa
     4681 taaacgttga ttaataaaaa ggtcatcaac cagatctttt aacataccat gtgtaacaga
     4741 tccgcttcga acaatttcca cagtaaaacc tgcttcttct aaagcgggct tcaatatttt
     4801 tgcacggtac atatccatag cgattttttt aatataatat ttattactca tttcaagaaa
     4861 ccaacctaca atataatcag cttctatatt ttttccatga acgatctgtg attttccttg
     4921 atctatagaa atatctataa cctctcgttt gatgttttgt aatcgaaggg ctgattcgtg
     4981 gataaaagta tgttgtgtaa aataaacatc tttatcgtat tttcctagca acccaacgct
     5041 ggcaaaatct cgtctatcag caaaatcgac tgttcctatc acttcatcca ttttttcagg
     5101 aaattctttt tctttcgtat gcagaacatc atcatatgaa gcaacagcaa atcgtgtatc
     5161 ttccataggt ctgttcattc gtttggtcat gaacgtaagt cttaaaccag cattacgttg
     5221 catttgagag tattcttgaa acattttccg ttttaaatct gcattgtaat taatagttgg
     5281 acaagctttt tcccacatgt cgggatcatc aacttcatta tcgttatcca agcgacaaat
     5341 aaatggaaac aaactagaaa attctgctcc atccttgtca attccaagtt ctccagaaag
     5401 aatcattttt gattcttcta taatgtcatc aagcggacca ccacgaacat gaccattagt
     5461 tgtatcataa aattctctat aatctcgaat tttaccacca ccagaagtag ccacatttat
     5521 cattgaataa tcttcatttt cgtgaatttc atcaaagcgg tttgcacctg gtcgcttccc
     5581 atcttttgtt ctagcatttg ccgtgttata acgaagtttg ctgtttgtag cgatattttg
     5641 aataacttcc ttcgtagctt taaatacttt tttatctaaa tcaggatgat ctttaattac
     5701 tttaaataca tcatcaaaac tagtctttgc ttggctttca ttattggcat agatatcaat
     5761 atcataattt ttaataccgt gtttagcggt tagtagaaag aagttgttcc aagaagcaaa
     5821 accagtttta ccattaccac gtcccattaa tgaaagatat ctattgaaca ctagtgtttt
     5881 atcttttttc catcgaacac cataaataaa acattgtaga aatttttccc acggaattaa
     5941 ttcgaatgga aagtattgtg ctggtatatt gattgaatcc tctaccatct gcttatcgaa
     6001 gtaaatatct tctctagtaa agactctttc ttctagataa ttttttagca ataattgctc
     6061 tttgcatacc ttgatagtgc cttcttctat agctttgaac caattttcaa tatgcttata
     6121 actcaggaat tgattcattt gcttcaccta ccaattcagg agtaatggca agtttatcca
     6181 acatcaatcc catttgtttg ttgacagaaa caagcaacgc tactgattca ttctttttac
     6241 cattctccag tctaatgccg ttctcggata tatcttcttc cagtgatatc gccgtttccc
     6301 ataaactgat ataacgatca acattatcta agaatggctc aatatttgtt ttctgacttt
     6361 ccaattggct tattaaagag cggcgtaatt tttctctgta gcgattttga gacaattcgt
     6421 ttttaaacat tttagccctc ctttcatgat aaagttcgaa aaaatctctt ttcctgacag
     6481 ccccctccgt ttcatcaccc ccaaaaaatt tgcgatttat tttaaggggg ggttatctca
     6541 ccatcggaat gaaagcttca gcgaagtcaa tgtaataatt aatctcttca atactatatc
     6601 caaaaacatt ttttattctt tcgacgttat tatctttatt caacgcttct cttacttgat
     6661 tcactttgta tttactacaa cagttatctg ataacagatc cctaatacct acatagcgaa
     6721 cgtatatcaa acgtttaatt aatccctgag tataagatga atactcttca atcttttctg
     6781 tatcatactc tctgccatta tcattgatga tcatgcactt accacctttc acttgcatcg
     6841 aagttagcaa agctttctat cttcttctct tgtttatcta atgctgtaag atatctgcca
     6901 tgaacttcat tatgatgttc aacacataaa caaataagat tatctaaatc taaagctaag
     6961 tcaggtctat ccttgacttc ctttatatga tgaacgttct ctactctatg atacttacct
     7021 agtcttctac actcttggca ttcatagtga tctcgtttca tcgctttctc tctaagcctg
     7081 cgccatttag gagactgata gaacttaacc aaacgatctt ctcttgtcaa ctgtaatagc
     7141 catctataga attcctcggt catgttccgt ctcctttcgc aatcttattt aatgcttagc
     7201 tattcttttg ccatacaatg gaataacttc attgttttcc tttcgtttat atgtatcgct
     7261 ctttattggt cttctatact catatacttt ttcgccatta cctttatgaa cagtgattac
     7321 ttcatacttc tgttctaagt attgtggtct atacattgtt gtttcctcct ttgtgcaaaa
     7381 ataaaaagac cactcaaaga gtgatctaat atgtaatagt aacttgcacg atgcacaaaa
     7441 cgcgtacgaa attgcgcacc cctatatttt taaaccgccg atgcctcggt tgcttaaagt
     7501 cgctggagtg ggattgcacc actcacgaga acttaccagg ctctcacgag gctactcgcc
     7561 atttaccgct gcgtcttcta cttccgccac agtgaccgaa gcttggtggt gtacagatag
     7621 cacacttact acattgccgt acgtagcacc gtatagcttc ttaacgatct tttttcggta
     7681 gtcgtaaccg tcataggcat ttaatgtcgc tggcaaggaa tcgaaccttg catggttgcc
     7741 gaagcattga cctagcacac atgcttagcg tctacccttt ccgccacagt gacactataa
     7801 aattattctt ggctgctact attttttatt ttgcccattt ttaaatccaa tcatatagac
     7861 attaagacag agcgcaaaaa ttgaaattat taatggaatc atttctcttc acccaccttt
     7921 agttatcgtg tgaataatta aaaaacaata gacagcaaca aaataacatt gctttgataa
     7981 tttggtataa accactataa atttcttttc ttgcaattat ttttaatata tgctagatta
     8041 tcaaccgata tagtcactgc ctgtactagc ggaaactagt gcaggttttt tgttctattt
     8101 actcaaaagt tattacgata aattaatatt gtgaaaataa atactaagcg tataatttta
     8161 tttatcagcg agtggtccgc tgaaatataa aacaaggatg tgcaagacaa catgtataaa
     8221 ccctacatga ttagttatga tcttaataac ccagggcaaa agtatgataa agtatttgaa
     8281 ataataaaag aatttggggc atatataaag ctacaaaaat ctttttggtt agttaaaact
     8341 aatttgaatc caaatcaaat gtgtgaaaaa ttaaatacag tacttgataa taacgattcc
     8401 ttattcatct gtgaactgca aaaaaattat caaggtagag ctacagagga aaattggaaa
     8461 ttcattaacg aacatatttt ctcttagtaa ggattagata ttttttctct gtttaaacaa
     8521 ttgcaaatac cgtcaatatc tgaattagaa acacttacct tttgctcctt gctactacca
     8581 atagcttgga gcaattcttg tatttcttct ggagtgcctt ctactgataa tttcattttt
     8641 cttccctcca atacataaat taatagacag cagcagttga aagacgacaa gaacatgttt
     8701 agttttgtga gtgctgctgt ctaatcaaaa taaacagcaa ccgatgaaga atttaggagg
     8761 agttgaattc acatcctttt cttcataatt agttgctgtc tatctaagaa gaagtttaaa
     8821 acgatgaggg agattgcctc ccttcgttta ttttgtcgat cctgtttcct aatctttcga
     8881 cactaccata ataacactgg taaatgtcta aaaaccgcca tcattccgcc aaaaaaccgc
     8941 caaattattt ataagcaatt atttttccgt gtttatatgc ttctgcaaac tctattagag
     9001 cttccgactt catccgttgt atacttcttt ctgaataacc cacttcacgg ctaattctgt
     9061 agtttgagaa gctatctggc acacagaagc tgtagtagag tatctgacga ctaatcagac
     9121 taagagccat caaagccgct agaatcgcat ctctctccgt ttctatatcc atcatctgaa
     9181 taatcgcgtc ttctgcctta ttgccatgct tcggtgcctt cggcatatcc gttataatcg
     9241 gcgacttaat atctatcaaa gagcgacctg ccatccgctc caaacgccga aagttcttca
     9301 gcacatctct cgcattacat cttgtctgtt tgaaatctac ctctcgtaac aattgcatca
     9361 agtcaaaccg ctcctttatg tgatataata aatgtgttgg atttattgaa tcagtcggag
     9421 cgatccggct ttttttattt gctcttgatt acttccatgt caactaatct cgctacagct
     9481 aaataatgct tgtgttttgc agtcgaacga tcacacttca ttgtattttc aatacgaatg
     9541 attgctgagt ttgacagtat ctttttaacg tatcctctga acggataaac gaactcttct
     9601 gcttcacagc ggaccatgtc accgactttg aattttgatt tcttgcgtgt tttagggttc
     9661 tttgtcggca tatctagcat taaaccgccg ataccgtgac tgctagcgta aaatccgtct
     9721 tttagtttca tctttctacc acctcttcca ctgttccatt caccaacaat gctgcagcat
     9781 ccgctgttgc tttatcagtg aaaagcaatc gatgagatgg attgcattca aaactataat
     9841 ttactccatc ttttccccat aaagcacatt tagtaagata gtttccatcg gcattcttta
     9901 ttgcccataa cggctctttc tcaacctcgt agccgttgta taggctcaat agtgtttcat
     9961 atgattgtct tgttgcccaa gcgagtaatt cttctccttg ctcttgcgtc actatgccat
    10021 ctcgtacaaa ccaatcacag aaataatatg aatcaccatc tttagatttg attaaatacg
    10081 ctattttttc agcttttgta aaagggtccg tagatttctc aagccaaccg gccacgagtt
    10141 gtggaataac tggtttctgc ggttcgtcta tttttttcat taacgtaata cctgaattta
    10201 tactctcgtt atagcaagca gctattgcat catttcctat cgctttaata ctttctaact
    10261 ttttgattgc ttcctgttta ttcatcgctg ttcctccaat aactcgctat tctcgtatat
    10321 atttccggtg acttcgtacg tgtattcttc aaacagctct gtgttaaaaa tttgatactc
    10381 taagtcttca tcaacagtgg cacaaactaa tccggaataa tctattgaat ttttgacaat
    10441 acagacttta ttatctaagt aatcgaagcc atttcgcacg ctgactaata ctatatcccc
    10501 ttcaaatata tccacaccat tcttatcttt cattcctgtg gattgcatga ggtcgatgtt
    10561 tcgcacgtga tatgatttca attcggtagg atttatccaa tattcaataa agtttgtttt
    10621 gccgttttta gtaaaatgca agacggctac atctctcatt acgttctttc gtttatccca
    10681 cgctctaaac ttcggtatca ttcgctgtcc tcctcgtatt tttcaatcaa ttccattact
    10741 tttttcacta tttcaaactc aaccgctttt gattcttcga aatcatgaac aatttctgga
    10801 aacagtacat catcaactac ccacaaaata atctggcgct ttccaccaaa atttatgatt
    10861 agatggtccg attccacaga tagtgttgct cctgattcga tatcatataa atccatgctg
    10921 aattgaacga gtttttttat catttgctgt cctcctcaaa tactcttcta atatttcttt
    10981 atacttctct acaaatttga aacgatcttg atgaagtttc ttgctccaat ttgtttgccg
    11041 atccagctca cgcatctgat cgaacccttt ttgaatttcg ttgtaataaa attcaatgtt
    11101 tgctgctgct ttccaatgcc tgctacttcg cactcctgct cctgtttcag ccatttctaa
    11161 cttaactaat tcagctcgtt cttttgattt tttatctttc tgaatcttca tcatgatttt
    11221 cttgaggatg atgtcactgt attgtgtaat gagatccatt atctctcctc cacataccta
    11281 aactgtcgtc cttttgaatc aatccataag ctcctagctc tatcccagat aatgtttttg
    11341 cttaatccag taatttcaga taactgttca gcagtacctg ttactaaaat tcggtcatca
    11401 tgccagattg caatttttct cggcgttctc cgtttgggct tttcagtcca cattgattta
    11461 ccgagctttt ggacttctgc aactatttct ttgtcttctt gccaagattc tgacttggtt
    11521 aattcagcaa ttcttttcat tgctgctttc ttatccacgc tcattcctcc aatcgatgga
    11581 tttcccttct taaattctct atgtgcaaat cgattgcctt tctcgccgtt tcattgacca
    11641 tcactgcctt tgttcgttcc agatcgtcaa tctcacgctg aaggcttcga atacgcattt
    11701 gaatcacttc ttctgttgtc atgatgattc ctccacgtat ctaaacgttc tcttcttagc
    11761 gtctgtgtag ccacaccttg ctcttttcct cacgattttc tcgtgcaagc ctgtgagact
    11821 tgctaactgt tcagctgtcc ctatcactag aagtttgtca ccgtgccaaa ttgcgatttt
    11881 tcgtggtctt ggcttgttgc tcttgtctgc ccacatcgct cttccaagcc tcatcacttc
    11941 tgaagcagct tctttgtcat tttgccaatc ttctgaataa gtcaattcga taattcgctg
    12001 cattgccgct ttcttatcca tcccgacatt ctcctttcag taatttgagt acttgatcaa
    12061 gtgcgctctc acgtccgccg tggaacgtgt tgagccactt gtcttcgtac gatacacttt
    12121 gtcttaaagc ttcttgatgc attagttcaa tctgtgctgt aaatgtcttt aggtccatct
    12181 gattacacct gctcaagttc attaagatgt ttttgcaagc ctttaacaca atcaacaaat
    12241 agtaatttgg tatatgctaa atttcttaat tgtgttgtat cgatataaag tgcgaaatag
    12301 tatctgagct tactccaact cgaacgatca ttcttaattc cttcgattcc agcttcttcg
    12361 agttgatcat atacgtctct caggatttct atttcctcac cagttttata ctttgctatt
    12421 tcattaatta gttctagata atcgattttc aatttcccac ctcttagaat ggtgcttttg
    12481 attgtctatt agctcgttct agcgcttttt tcttgagata ggcttcttgg tcgattgccc
    12541 actcaggaag cttctctcgt cttcctgtgc gcttgtatcc actgcttgcg ttcttagatt
    12601 cacttttttc ttttcttgcc cagcttcgaa tagttgccaa atagttttta taagtcttac
    12661 cagatgattc acaatactca gatagccgtt ctattcgctc ttggtagtca ttagggaatt
    12721 ctattttgag tttctccatc tgctcatctg acaaaagaac atttttatac tctccgtatt
    12781 tatgacggac gggcttagcc ttcgattttt tcgaaggcgt tacattctct atatctttct
    12841 ctaactctat atctttctct aactctatct ctaactctgg tgtagttttg tccggacatt
    12901 tgtccgacat ttgtccactt gttattaaat tctgttttgc ttcctcaatt tcttttctgt
    12961 attttctctt cctatcagct tcagttgaag atttcccaat aaaactttgt atatcagaca
    13021 tataaattgc tccgttatct aatacctcaa taagttgtaa atcacgaaat atttgtactg
    13081 ctttttctac aactcccaca gagtgtcttg taatagtcgc aagcattgta gaattgaatg
    13141 gaatcctgtc attaaacatt agtttgcctt catgtttcag acttcttaaa taaagtttga
    13201 gaagaatatt agaataaatg tatccatctg gcatactttc taaaagaacc atctcgtcgc
    13261 tatcgaaaaa gttctctttt agttttaaat agtagtatcg tttgtt
//
LOCUS       DAZULR010000063        13086 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.065, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000063 DAZULR010000000
VERSION     DAZULR010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13086
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.065"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(79..2199)
                     /locus_tag="ACG8ZV_002342"
     CDS             complement(79..2199)
                     /locus_tag="ACG8ZV_002342"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFS4997617.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLAKGKNVIYIHLESFQQFLIDYKLTDENG
                     LQLEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHKG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2429..3607
                     /locus_tag="ACG8ZV_002343"
     CDS             2429..3607
                     /locus_tag="ACG8ZV_002343"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HFS4997618.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIVGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3623..4381
                     /gene="aroD"
                     /locus_tag="ACG8ZV_002344"
     CDS             3623..4381
                     /gene="aroD"
                     /locus_tag="ACG8ZV_002344"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HFS4997619.1"
                     /translation="MVWVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLAGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4404..4889
                     /gene="ybaK"
                     /locus_tag="ACG8ZV_002345"
     CDS             4404..4889
                     /gene="ybaK"
                     /locus_tag="ACG8ZV_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_process: GO:0043039 - tRNA aminoacylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HFS4997620.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSHIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4960..6213)
                     /locus_tag="ACG8ZV_002346"
     CDS             complement(4960..6213)
                     /locus_tag="ACG8ZV_002346"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFS4997621.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6329..7678
                     /gene="gdhA"
                     /locus_tag="ACG8ZV_002347"
     CDS             6329..7678
                     /gene="gdhA"
                     /locus_tag="ACG8ZV_002347"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HFS4997622.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNAQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7790..9136
                     /locus_tag="ACG8ZV_002348"
     CDS             7790..9136
                     /locus_tag="ACG8ZV_002348"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HFS4997623.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9444..9830)
                     /locus_tag="ACG8ZV_002349"
     CDS             complement(9444..9830)
                     /locus_tag="ACG8ZV_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFS4997624.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYTEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
     gene            complement(10098..10247)
                     /locus_tag="ACG8ZV_002350"
     CDS             complement(10098..10247)
                     /locus_tag="ACG8ZV_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997625.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            10709..10921
                     /locus_tag="ACG8ZV_002351"
     CDS             10709..10921
                     /locus_tag="ACG8ZV_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997626.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPTELVS"
     gene            complement(11199..12998)
                     /locus_tag="ACG8ZV_002352"
     CDS             complement(11199..12998)
                     /locus_tag="ACG8ZV_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HFS4997627.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRSFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
BASE COUNT         4291 a         2354 c         2577 g         3864 t
ORIGIN      
        1 ttattctaag atttctcttt accaacatca tttgacaaag agcctaattt tgtcgctgct
       61 ccttttaaat ttattttatc attcggaaga acttgtggtc gttccgtgaa gttcttggta
      121 cgtttgcgtt ttataaagat caacagttga ttgtcccttg tgttcactaa agacactagt
      181 tgacttgtca ccaagagatt tttcagcttc ttttaatttc tctaagccat tcttgtagtc
      241 ataatcactg gtatcaattg ggtctaatcc actattcgta tagaaccgaa gaagatcacc
      301 attattgatt tggtcagaaa cagctaactg tttatcaact ttttctttca gtgaatcaat
      361 ttcattctgt acttcctcag taggttcagt aatagcttca ccagtttcgt tactatagat
      421 cgtaccaccg tagtaagtat attttggtgt aacaaaatca ccatcacgga aagaaacaag
      481 ctgttcatga tctttcgaga atagatcttg tcctaactga atataatttt ttgtatctac
      541 acctagtaag tgaagtaatg taggcaaggc atcaacttgt ccgccgtaag tgtgattgat
      601 tccgccctgt gtttgtccag ggatatggat catataaggg acacgctgca tttgtgcatt
      661 gtcgtagttt gtccaagtag aacttgtttt tccaactaat tcagctagat ttttatttct
      721 tgaattcgag acaccgtaat ggtcaccgta aaggacgatg actgaattat catacaagcc
      781 gctttctttc aaataattga agaattcttg tacggcggta tctaaataat tggctgtcgc
      841 aaagtaaccg ttgatcgttt catcatttgt attggctaac gggaatcctg cttcgtcatt
      901 ggtgaatttt gaataaggat aatggttaga tacagcaatg aattttgaat aaaatggttg
      961 ttgcagacgt tccaagtatt gtacggattg ttggaaaaat ggtttatcat gcaacccgta
     1021 ttggaacgaa ttgtcatcat taacatcata ataagaagaa tcaaagaaat aatcatatcc
     1081 taaattcttg tatgtctcgt ttcgattcca gaatgtacca gcgttcccat ggaataccgc
     1141 actagtgtaa ccttgtgttt gacttaaaat atcaggtgca gcttggaaag tattttttcc
     1201 gcctaattgt gtgaacaagg agccttgatt caagccaaac aatgaatttt ccatcagcgt
     1261 ttccgcatcg cttgtttttc ctgcttttac ttgatggaaa aagttgtcaa aactgaacgt
     1321 gctgttgctg tggtaaagac tattgatgaa aggtgtaact tcaagctgga gaccattctc
     1381 atctgtcaat ttataatcga tcaggaattg ctggaagctt tctaaatgga tataaatcac
     1441 attttttcct ttagcgagcc cgaacaaatc atcatttggt gctgcataat gttcttttac
     1501 ataattttct acttctttca tatcattggg acttgcttct gcccgcactt ggtttgtctg
     1561 gtaagtttga acaccgtcat aaaccatgaa agcattcaag ccaagatatt tgaccaaata
     1621 atcacgagag aatgttcgag tcagcaattc tggacgatca gcttccgcca taaaaagatt
     1681 tcctgagaaa atcataactg ctaatgtaga gatcgcaaaa gccattcttg ctcggatcgg
     1741 gcgagggtcc aacttgattt tttttgcaat cagcagaaca gtcaagataa taaaatcgat
     1801 ccaatagatc acatcatatg ggcgaaacag tcgaatggca ctttctccca gaccactcgc
     1861 tactttccca gcacctaaaa tcgtgttgat cgtaatgaag tccgtgaatt ctcgataata
     1921 agtgacattc gaaaaaacaa gcaatgtcaa aagaaaataa atgaccatca tcgtgatata
     1981 agcaactcta gggcgtctga tataaagagc aattccaagt aataacaatg tagttgcaat
     2041 agggttgata aacaagataa agtattgaat gccactttcg attccgagat ggaaatcaac
     2101 taaataggca aaaatcgttt tcaaccaaag taaaacaact agtaaagaaa aaaatccgag
     2161 cctcttattc aaaaaggcag gtgtttttat acatttcaag ataatcttcc tttctgcact
     2221 tcttaatcac agaagtgtca tgaaaccatg ttacacagct cacttattct catttatttt
     2281 actagtatga caatatagtg tcaattgaaa ccagaagttt atgctgtttc attaaggttt
     2341 tctttaagct tcatgaaaaa atgagcagta agacaagtcc tatgtttttt gttatacttg
     2401 ggaagagaaa gctaaagcag gtgaaggaat gaaagtaaaa gtaaaaaaaa gagcaagcaa
     2461 tcgattgaaa aaaggatatc cactgatcca aaaagaagac cttgctcatc cccaaaaaga
     2521 aaccacgcaa tgggtggaat tagttgattc gcaaaaccaa tttatcgcaa aaggatatct
     2581 aggaaagcag aataagggaa tcggttgggt attgagccag cagaacatcc catttgatca
     2641 atcttttttt gaagaatttt ttgtgaagtc aaaagaaaaa agaactttct ttttttcaga
     2701 tgattctact accgcttttc gtatattcaa tggagaagga gacgggatcg gcggtctgat
     2761 tgttgattat tatgcaggtt atgctgtttt ttcttggtat aacgaaacgt tatatgcaca
     2821 tcgtgaatta ttgattcaag cttttcgtga aatctacccg gaaatcgtag gaggctatga
     2881 gaaaattcga tttgaatcag taaatctgcc tgagagccag ttcatttacg gaaaagaggc
     2941 accggaaccc ttgatcgtaa aagaaaacgg agtaaaattt gccgtttatt taaatgaagg
     3001 attaatgact gggatctttt tagaccaaaa agaagtacgg ggatcattag cagaaggttt
     3061 cgcttctggg aaaacagttt tgaacatgtt tagttatacc ggcgcctttt ctgttgctgc
     3121 cgcaatggga ggggcaatcg aaacaacaag tgtcgatcta gcaaaacgca gtttaaaaaa
     3181 aacacaggaa cagtttgaag tgaatggttt ggatgtcgat cagcaaaaaa tcattgttat
     3241 ggacgtattc gagtatttca aatacgccaa aagaaaacaa tttttatatg acatgattgt
     3301 attggatcca ccaagttttg ccagaaataa gaaaaaagtc tttcgcgtag caaaagatta
     3361 tggggaactg gtcaaggata gtctggatat tttagcagaa gacgggatac ttattgcgtc
     3421 tacaaatgct gcgaatgtct cgatagaaca attccaaaca atgattgaag aggaattcca
     3481 tgccaaaaat gtttcttttg aacaacttgc tttatatcgt ctgccaaaag atttccagac
     3541 gacggatacc tttttagaag gcaattatct gaaagtgttt gtttatcaaa ttaaaaataa
     3601 ccattagaag gagcgatgca gaatggtttg ggtaaaggga ttgaatatag gaagcggtag
     3661 accaaagatt tgtgcgcctc ttatcggggc cgtccgagag gaagtattac gtgaagcagt
     3721 tcttgcacgt gaagcagggg ccgatttagt cgaatggcga gtcgatcatt atcgtgaagt
     3781 tttttctttt gatgaagtag cagaaacatt ggttcttatc catgagatgc ttgatggact
     3841 gccgttatta tttacgtttc gtaccttagc tgaaggcgga gaacaagaca tatcgatccg
     3901 tcagtatcgc gacctttatg aacatgtgat acacacagga ttagtagata tggtcgatat
     3961 cgagttgttc aaagtagaaa gtctaggaaa aagactgata gaggaaatca agtctttaaa
     4021 cattccttta attatcagta gtcatgattt taaagaaaca ccagcagacc ctgtcttgct
     4081 ttaccgattg aatgttatgg aacattttgg agccgatatc ggaaaactgg cagtaactcc
     4141 caataatgaa cgagatgttt tgcggttgat ggagttgact agacgggcaa atgcttttgt
     4201 ctccatgcct attattacga tgtccatggg aaatcttggt aaaatttctc gtctggctgg
     4261 cggaacgacg ggttccgtta tgacatttgg ttccttaagc agcgattcta cttctgctcc
     4321 aggacaatta ccggtcaaag cattgaagca aattattcaa ttattaaatg aaccgttgta
     4381 gaacaagttt gaggtgatat tttttggcaa agaaaaaaat agtaaaaacg aatgcaatcc
     4441 gtatggtcga acaaaaaaag attccctata cagagcacga atatgagtgg gacgaaagcc
     4501 acctaagtgc gtcatcggtc gctgaacagc ttccagaaag ccaatctcat atatttaaaa
     4561 cactggttgc tgtgggcaat gtgacggggc ctcttgttgc tgtgataccg ggagaagccg
     4621 aattgaatct aaaaaaatta gcaaaagttt cagggaataa aaaagtagaa atgctccatt
     4681 taaaagattt ggaagcaacg accggataca tacgtggtgg ctgctcgcct ataggtatga
     4741 aaaaactatt tcctacttat ttagatcaaa ttgcagaaag ctatgaacaa atcattgtct
     4801 cggctggcag aagagggcta cagatggagt tagcacctca agatatctgt gcattaacga
     4861 gcggacaatt tgcagatata aaacaataaa tcatacgtat aaaagaaaga aggaggccgg
     4921 gatgttgttt gtccagtctc cttctttctt ttttatacat tatgctcttt gcccggcatt
     4981 cattcctgct acatgccctg tagcgaaagc cgctgtgata ttaaagccgc cagtataacc
     5041 attgacatcc agtaattctc ccgcaaaata cagaccatca atgattttac tctccaatgt
     5101 tttaggataa atttccttta gagaaacccc tccgccagtt acaaatgatt tctcaatagg
     5161 aaaagttttg ttgattgata gcttaaactc tttgcatagt tgaacaaaat cttgaatttg
     5221 tttttgagag gcttgttgtc ctgtcagatg atccatttca agccgctcaa gaaagaaaac
     5281 taacaatcgc tcaggcaata taccatgcca agcattgacc aagttctttt tggttgcttt
     5341 acttttttct gtcaatatat gaataagctc ttgtttggtt tgtgtaggga aacaatccag
     5401 agaaagtgtc actggttctc ccgttttctc taattcttta ttgacaaaac ttgaacaacg
     5461 cagtgcagcc ggaccagaaa taccgaaatg ggtgaaaagt aaatccatcg tatgttcagt
     5521 caatacacga ccttttttat ttaaaacgcg taaagtgatg tcttgtaaag aaagcccttg
     5581 aagtgttttc tcctgaatat acggttcatc cgatatcaag ggggactctg tcgcataaag
     5641 aggcgtcacc gtgtgaccca ctcgcttcac gatcttgtac ccatctccag tagaaccagt
     5701 agatggataa gtccgtccac cagttgttaa gataatggca ggagcatgga actcttcgaa
     5761 ttccgtgcgt ataccgtaaa ttttatgttc tttgtggatc aatttctcta ctcgagtaga
     5821 gaatagaagc gtcacatcta gttctttcag acgattgagc aatgcttcga taatcgtttt
     5881 tgatttattt gttacaggaa acatccgtcc atgatcctct tcttttaaat gtacgccttg
     5941 tgattcaaag aagttcatga tatcgaaatt attccattgc gcaaacgtac tatataaaaa
     6001 ctttccattt ccaggaatat gtgcaatcaa atcatcaaca ggacgattgt tcgtaacatt
     6061 gcaccgacca ccacctgtca tcagtagttt ttttcctgct tttttgtttt tttcgatcaa
     6121 gagtacgcgt gcgccttgtt cagctgcact gatcgctgcc atcatcccgc ttgttccagc
     6181 gccgactacg atcacatcat acagtttttc cattccctca cctcaaggaa agtgtagcat
     6241 atctgaagaa agaaaacaga aaaaatgttt tgagccaaaa gagaaaatga gctaaaatga
     6301 gggaagataa gcaaaggagc gtggaacgat gacaaacgca acagaatatg ttcaagcaat
     6361 tcaagaaaag ctacatcaaa aggatcaagg gcaagaagaa tttttacaag caatcgatga
     6421 attcatgccc acggttatgt cttttttgga cactcatccc gaatatatcg aaaagaatat
     6481 cttagaactt ttaacggaac cagaaagagt tattcaattt cgagtgcctt ggcaagatga
     6541 tgaaggaaac tggcgagtaa atagagggta ccgtatccaa tacaactcag ctatcggccc
     6601 ttataaaggt ggattgcgct tccatcctag tgtcaatcta agtatcttga aatttttggc
     6661 ttttgaacag attttcaaga atagtttaac cggtctgcca atcggtggag gaaaaggcgg
     6721 aagtgacttc gatcctaaag gaaaatctga taatgagatc atgcgttttt gtcaaagttt
     6781 catgctggaa ttgtcaaaac atatcggccc atcgattgat gttcctgcgg gagatatcgg
     6841 tgtaggagct agagaaatcg gctatttgtt cggcgaatat aaacgattga aaaaatatga
     6901 tactggtgtg ttgacaggta aacctttgga tttttgggga agtaagatac gtacggaagc
     6961 tactggttat ggattagtgt attatgtcaa acatctattg aacgaagaaa aagattcatt
     7021 taatcaaaaa acagtttttg tttccggaag cgggaatgta gccatttatg caatcgaaaa
     7081 agtgcaagag ctaggcggga aagttgttac atgttcagat tctagcgggt acatctatga
     7141 tccagaagga atagatgtga aactattgaa agaagtcaaa gaaatcaata gacaacgttt
     7201 gacggaatac gcaaaccaac gtccttctgc tatttatcat gctggagaat ctgtttggac
     7261 attgaaagaa aaagcggata tcgctttgcc atgtgctact caaaatgaaa tagacgaaag
     7321 cttggccgaa atcttagtag aaaatgggat caaaatcgta gcagaaggcg ctaatatgcc
     7381 atgtacagta aaagctgttt ctgttcttca tgaagcaggc gtgtggtatt gtccaggaaa
     7441 agctgctaat gctggaggag tagcagtatc tgctttagaa atgagtcaga acgcccagcg
     7501 attgacttgg gaaagagagc aagtggatga gcagctggat caaatcatgg aaacgattta
     7561 ccatacgtgt cgccaaacag cagccgagta cggcgacgaa aaaaatctgc ttcttggagc
     7621 aaatgttgct ggatttgaaa aagttgccaa agcaatggca gcagaaggtt tagtttgaaa
     7681 aatgaaactt tcttggaaat attgtcagca ttttgtttat ttgcttgaaa aataataaaa
     7741 aaaaacgtaa agtattacct gtagagtaaa cctataagga ggagaacaaa tggcacacat
     7801 tcattttgac tattcaaaag tagcaccgtt tgtcaacgaa caagagttag ggtacatgca
     7861 aagccaagta acagcagccc acaacgaatt acgggaaggt actggcgcag gaagcgactt
     7921 ccgcggctgg atcgatttac caacgaacta tgacaaagaa gaatttgcac gtatcaaaga
     7981 agcagctaaa aaaatccaat ctgattctga agtattagtt gttatcggta tcggtggttc
     8041 ttatttaggc gctcgtgcag cgatcgactt cttgaatcac acattcttca atttattaga
     8101 tagcaacaca agaaaagcac cacaaatctt ctttgccgga aattcaatca gctcaacata
     8161 tattgctgac ttgatcgaag taatcggtga tcgcgacttt tcagtaaacg ttatttcaaa
     8221 atctggaaca actactgaac cagcgattgc gttccgtgta ttcaaagagc ttcttgttaa
     8281 gaaatatgga caagaagaag caaacaaacg tatctacgct acaacagata aagcaaaagg
     8341 tgcagttaaa gtagaagcag atgcagaagg ttgggaaact ttcgtgattc ctgatgacat
     8401 cggcggacgt ttctctgtat taactgctgt tggtttgtta ccaatcgctg ttagtggtgc
     8461 agatatcgat gcattgatgc aaggtgccgc tgatgcaagc aaagcatact caagcgacaa
     8521 actagaagaa aacgaagctt accaatacgc agcaatgcgc aacattcttt accgtaaagg
     8581 caaagtaact gagttgttga tcaactatga accaggaatg caatacttct cagaatggtg
     8641 gaaacaattg tatggtgaat ctgaaggaaa agaccaaaaa ggcatctatc cttcaagcgc
     8701 aaacttctca actgatttgc actctttagg acaattcatc caagaaggac gtcgcaatat
     8761 ttttgaaaca gttgtgaagg ttgaaaaacc tcgtaaatca atcacaattc ctgaacaagc
     8821 agaagattta gacggtctag gctacttgca aggaaaagaa gtggacttcg taaatacaaa
     8881 agcatttgaa ggaacattgc ttgctcatac agacggtgac gtgcctaact tgctagtcaa
     8941 aattccagaa atggatgctt atacattggg ttatacaatg tacttctttg aaattgctgt
     9001 aggtatttca ggttacttga atggaatcaa cccattcgac caaccaggtg tagaagctta
     9061 caagaaaaac atgttcgcac ttctaggcaa accgggcttt gaagatcttg ctaaagaatt
     9121 gaacgaacgc ctgtaagata agggtttttc gctagattta aataatcagt gatagaaaca
     9181 tgttcgcttt aaaatgaaaa ctggtaccca tttaggtact caaacatact gcatcgttta
     9241 ttcagaataa ggggctgtga caagacgttt gtcacagtcc cttgtttgta tagaaatcga
     9301 ttgattgcct tgctctttag tttgttttag gactttaaga acagtgaggc tgacttcgaa
     9361 ggttaattct gtttttttgt tttctagaat cagtaagcaa aaaagcactc acttcgagtg
     9421 cttttttgcg atatattctt agcttaagat aggcctaatt tttcttttac agatgagggt
     9481 accttatcgc tggtaattac ttttttctct atgatccgct tttcgcttgc tttcaactgc
     9541 aagatcgttc cttcggtgta agcagaacca ttggcagagt caccagaagt aatgacatcg
     9601 aaatctaact gtcttttttc accgttttca gcataagcat ctacgttgta tttaaaacct
     9661 cttccaatta cttccccatt atctgctttg atatcagttt ctgcaggcat tggagctttg
     9721 actaccgcat aataatcttt acctacataa gtagactgat agtagtccca acctttccat
     9781 cctataaaag caatcaatat gataacgatc aaccctaaaa tttttttcat gaaagatctc
     9841 cttttttatt tttattatat taaatattat acagataata acggaatatt atcatcgaaa
     9901 cagctaacaa aattgtcata aaaaacgaga tggttgatat tagaacttgt gtttttgttt
     9961 aggtctagag ataaagagag acaatttcca aatatatgta atgaatacaa aaagacgttt
    10021 gtcgcggatt accgttacaa acgtctttta ttgattttcc gagatctcat cagtcgccat
    10081 ttggaatggt tcactcctta tctagattcg tttaatgctc ggactgcttg ttcgattgta
    10141 ataccaaacg caacgttatt ttcgttttgt gcatcaatcg ccataaaacg gttagaagtt
    10201 gtatcaaaag ctacgcggta ttgcatattt gtttttgtaa acgtcataaa attcatctcc
    10261 tttgtaatgt aatttagttc ttgaaagttt cctttaaact ttcgaactta taccaagttt
    10321 agcatcgtac gttttttgat gcaattaaaa agcatttatc attttcctta tttatttttt
    10381 cttaaatggt ttagctattt tcttttaatc cgataagtag cccaatcatc aaggttacaa
    10441 atactattgc ttgaatataa atcatatgct cacctcttta taaataactt agcaatataa
    10501 agaaaaaaac gcacgaacaa cataggaata taaacaaacg tttttgtcac aacgtctaag
    10561 atcgtgttaa aaaatagtta tctaaaaagc agaaagatac tcaaaataaa aaataaaaaa
    10621 atgaataaaa acgttttcaa atacaaggta atttgttatt ataaaataaa gaaaaaacaa
    10681 aataaaaata aagaaaagag ggaatgaaat ggtaaaagca gaagtaggaa gatcttatat
    10741 atgcaaaccg atcggagtat ctcatgaact aatcggctgt attgaacgta catatatcaa
    10801 cacggctgtc gtgtatgttg aaagttatga ccaacgagac tatcaactta tcaatgaaag
    10861 caagtatcgc atgctcgtaa aattctgtga tattagcgca cctactgaat tggtttctta
    10921 aacagtattt ttgagaattc gcaagaactc ccttataata taaataaaga cagaagggag
    10981 cgagaagata tgccaaaaag aaaaagttca gggaaaatgg gaattattct tgcagtgatc
    11041 tctgcaattc ctgctatttt agctattgtt cgtgcgatga aggaatcaag agaaagttaa
    11101 gcacacatta tgagcgtcaa acaaaaaacg catatacctg cggtggcagg ttatgcgttt
    11161 tttgttgtat aaagactttt ttcattaacg atttttgatt agccgactcc caaaacaaaa
    11221 tttagcagtt tatctgaata agtgatttct tcatctgttt gtttcacact ttcatttagt
    11281 agtcccatct catcggttat gataccatcc acaccataaa acatcatgcg actcatggca
    11341 tctgaatcgt tgattgtcca tacatatact tcttttccgt cttggtgggc agaattaatg
    11401 aagttacggt tgatcgtact atattccatt gtcagaaaat cagcaggcgt cacagggggc
    11461 ccaacaatat tgaaaggtaa gatgtagccc acataaaagt ttggttctgc ttcttttaaa
    11521 tctgaaacgg tttggtacgt caaactttgc aaaatatgat ggttctctaa gataactttg
    11581 cggtatttat ggacaaatcg ttcgacaagg tcatccgaat cttttttaga ggtcttgatc
    11641 tcaataagta atttttggtt tagcttatgt gctttttcca aataagaatc aaaagaacaa
    11701 acaggggctt gcactccgtt ttcagtaact gtaagatttg tcaattcttt caatgtaaga
    11761 tcctgtggtg ttccatttac ccctgttaag tgacgaagat ttgcatcatg catcactacg
    11821 aaatgaccat cttttgtttc ctgaacatcc atctctacat aatcaggatg atagtctctg
    11881 cttgtttttt caagtgcttc taaagtattt tgcgccccat tttgggtact cacacctctg
    11941 tgagagacag tcactggttt tgtctgaaca gctgaagtca gataatccat attgtaaaga
    12001 cagacgccaa taccgaaaaa aactgcaaaa agagtcaaac cagtgttttt cagcgcagag
    12061 aaacgcaagt tgggggcttg tgggataaac cacttaggga tctcaggcaa gaagccttcg
    12121 tcatccatga aatcaacaat gatataaaaa atccctacgg tagacatcac gatattgaat
    12181 aataaaatcc cttgtaaaag cgtcatagca aacacagcgc tgatcaatgc atagtctggg
    12241 aaaaattgtt caaccatact ttgtgccaaa ataacaacga tatatcctaa agaagaaagg
    12301 agtaaaatcg taccgccaat cacaataaat tggcccgtga tggccaaaag acgcgatttg
    12361 gtcaatgacc agctttcccg aatggctgct cgaaaagaac gatctcgtag aatcatttcc
    12421 ggtaaagcaa aaatcagtcg aatcccaata tagccaagga aaatataaac gagtaaaaag
    12481 gaactgacga tgatccaacg attagcaaaa ataaaatcca taatgaaagc ggggattttt
    12541 atttttgaca gtagatcaga attaaaactt aatccgctga tcggtagaat caataaaaaa
    12601 taagcaagga aaaacaaaaa agtaatgggt ctcactttct tcagctgaag tatcgtcaag
    12661 tgtaagagtt gcttcaaaga gattggttct ttctttttaa taaaaaaaac actcatcaaa
    12721 agaaaagtaa attcgaaata aactaacagt aaaatcgtca tcaaaactac gattaacgag
    12781 agtagaaccc caggatgttg agaaaaaatt gaaggaatat tgtcataaga caaatagtca
    12841 attgcccctc ggtgtaaaat aaaacgggtc gtactgctca ataagggtaa acaaataaat
    12901 aaaataaagc catgcatcag caagacatca cggaaataag cttgtgttcc ttttaaaaag
    12961 tcccaagcat tacctaagct acgtttcaaa taattcatcc tatcacctgc tcttcacatt
    13021 gtagcgcaaa tctaatgaaa aaggaaaggg tgcagtgtgt tttgcagacc ctttcccaga
    13081 tttaac
//
LOCUS       DAZULR010000064        12136 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.066, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000064 DAZULR010000000
VERSION     DAZULR010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12136
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.066"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..610
                     /locus_tag="ACG8ZV_002353"
     CDS             <1..610
                     /locus_tag="ACG8ZV_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFS4997628.1"
                     /translation="KRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWIQLIL
                     DEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSKITVF
                     PKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAYTIQN
                     ATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            723..1001
                     /locus_tag="ACG8ZV_002354"
     CDS             723..1001
                     /locus_tag="ACG8ZV_002354"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4997629.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            1119..1355
                     /gene="secG"
                     /locus_tag="ACG8ZV_002355"
     CDS             1119..1355
                     /gene="secG"
                     /locus_tag="ACG8ZV_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HFS4997630.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            1458..2213
                     /locus_tag="ACG8ZV_002356"
     CDS             1458..2213
                     /locus_tag="ACG8ZV_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFS4997631.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            2216..4573
                     /gene="rnr"
                     /locus_tag="ACG8ZV_002357"
     CDS             2216..4573
                     /gene="rnr"
                     /locus_tag="ACG8ZV_002357"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HFS4997632.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKSGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKDVKKKKKKK"
     gene            4595..5059
                     /gene="smpB"
                     /locus_tag="ACG8ZV_002358"
     CDS             4595..5059
                     /gene="smpB"
                     /locus_tag="ACG8ZV_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HFS4997633.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIVRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            5361..6080
                     /gene="atpB"
                     /locus_tag="ACG8ZV_002359"
     CDS             5361..6080
                     /gene="atpB"
                     /locus_tag="ACG8ZV_002359"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HFS4997634.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            6133..6348
                     /gene="atpE"
                     /locus_tag="ACG8ZV_002360"
     CDS             6133..6348
                     /gene="atpE"
                     /locus_tag="ACG8ZV_002360"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HFS4997635.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            6439..6963
                     /gene="atpF"
                     /locus_tag="ACG8ZV_002361"
     CDS             6439..6963
                     /gene="atpF"
                     /locus_tag="ACG8ZV_002361"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HFS4997636.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            6950..7492
                     /locus_tag="ACG8ZV_002362"
     CDS             6950..7492
                     /locus_tag="ACG8ZV_002362"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HFS4997637.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            7515..9071
                     /gene="atpA"
                     /locus_tag="ACG8ZV_002363"
     CDS             7515..9071
                     /gene="atpA"
                     /locus_tag="ACG8ZV_002363"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HFS4997638.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGSNSST
                     EDKLKSIQNA"
     gene            9085..9987
                     /locus_tag="ACG8ZV_002364"
     CDS             9085..9987
                     /locus_tag="ACG8ZV_002364"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HFS4997639.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMFQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            10010..11416
                     /gene="atpD"
                     /locus_tag="ACG8ZV_002365"
     CDS             10010..11416
                     /gene="atpD"
                     /locus_tag="ACG8ZV_002365"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HFS4997640.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            11430..11852
                     /locus_tag="ACG8ZV_002366"
     CDS             11430..11852
                     /locus_tag="ACG8ZV_002366"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HFS4997641.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
BASE COUNT         4035 a         2155 c         2677 g         3269 t
ORIGIN      
        1 taaaagatat gcagagaaag gattcaacgt tcttgtacct gatttacgtg cgcacggaga
       61 aagtgaagga gaaatcatcg gaatgggatg gctagatcgg ctagatttaa ttgcctggat
      121 ccaactcatc ttagatgaac agccgaatgc gtccattatt ttacacggcg gatcaatggg
      181 agcttctacg atcatgatgg caagtggtga aaaacttcca tcagcggtca aaggatttat
      241 tttagacagc ggatatgttt ctgtttatgc agaattccga tatatgttaa gtaaaatcac
      301 tgtctttcct aaaaaaatgg tcatgagata tgcgaatcat tatgcccaga aatacgccgg
      361 ttactcctta aagcaagcat cagctacgag acagcttggc agcaaccatc tgcctttatt
      421 agtcatccat ggtgaaagag atcattttgt ccctacagaa gcagcgtaca cgattcaaaa
      481 tgctacggca ggggataaag cactgctgct tgttccagaa gcagaacact tggaagcatc
      541 gatgaaagat ccgaaaacct attggacagt gattttttca tttattgaac aaagaataac
      601 gatggattaa ttttctcttc ttttttgtaa gtaattcgag gataaataat tgtttataga
      661 tctggagact gctaaaataa ggtaggaata aaaaaatatc agttatttga ggagtgcggc
      721 atatggaaat caaagaagaa aaaaatcgtc ttgctttatt caatgatgag caacaagaga
      781 ttggagaaat gacatggtca gatgcgggcc cagacatcat gatcattgac catacatttg
      841 tagatccagc atatcgtggt caaaagttag ctgaaaagct agtgtatact ggagtagaat
      901 tagcaagacg agacgggaaa aagatcattc ctttatgccc ttatgcaaaa aaagagtttg
      961 aaaagaaacc agaatatcaa gacgtcttac gtcagtcata agaataacag ctgaaagttt
     1021 tgaactttca gctgttattc catttatata gagttgtcac ggacttttat ctatgataaa
     1081 gttaaagaga cgatatcttt tgggaaggag gctgcgatat gtataattta attttgggaa
     1141 tcgtgatcgt tttatcgatt gttatggtca ttgcgattat gatgcagcca agcaagcaaa
     1201 atagtgcagc gagtgcattt accggcggtg cggatcaact attcggcaaa caaaaagctc
     1261 gcggctttga agctgtcatg cagcgatcaa ctgcagttat gggagctatc tggatgatct
     1321 tattatttgt cctagcatat ttatcttcga agtagttgaa taagcctctc gcaaaacggc
     1381 gggcggcttt ttttattgca aagagaacgc ttaagaagaa gttatgaaag aaactatggt
     1441 aaaatgaggc gaaagaggtg agacgagtga gacaattacc aaaacccctt tatgcaaaac
     1501 atggaaagcg agcggttttg ctgcttcacg cttactcagg aagtccaaac gatgttcgaa
     1561 tgctcgcacg atttttggaa aaagcagatt atacagttta tgcgccgctt tttaaaggac
     1621 acggaacaat ggagccatat gatatcttgc aagaaaaagc agaaagctgg tgggcagaca
     1681 ctaaaaaagc catccatttt ttacagtctg agcagttttc tgatattgcc gtattaggat
     1741 tatcaatggg cggcatcttt gctgtacgag cactagaaga agaatcagtg attggcggcg
     1801 gttttttctg ttcgcctttg tctcctgtaa aaacaaacgt gcctgaaaac tttgaaaaat
     1861 acgtacgtca agtgctgaag acagcaggta aatcagagaa agaaatcaat gaaaaagcag
     1921 ttgcttaccg ctcgttagct gaacaacaat taatggatat acaagatcag gcagcaatcg
     1981 tagaaagtag gttgtcagat atccaacagc cgatattttt agctcaagct gggaaagatg
     2041 aaatgatcga ccctaatggc gtatttgaaa ctgcacgcaa gttgagccgt cagcgagtga
     2101 cacttcaatg gtatcctgaa agtggtcatg tgattacagt tggtacagca agacgcgaat
     2161 tagaaaaaga cgtcttggaa tttttagaaa aattaccttg gaatgaggaa taaatatgac
     2221 aaaagaaacg ataaaagaga aaattctctt tttcatggaa agcagtcgca aacgcagttt
     2281 ttctatggaa gaaatcgctg aaggtttagg gttccaaaaa agcgatgatt ttaaattact
     2341 agtacaaacg attgctcaaa tggaaagaga acagagtata gttttcaata aaaaaggaaa
     2401 agtgaaactt cctttaaaac caatcttgat cgaaggaaca tttcgagcaa atgaacgagg
     2461 atttggattt gtaacgattg atcccgaaga agatgacatc tatatcccaa aagaagcgac
     2521 tggttttgca atggatggag acaccgtagc aatcgatatc atgaagcgag caaatacaga
     2581 tatggatcgc ggagcagagg ggaaagtagt cgagattcga gaccgggcga ctactcagtt
     2641 agcaggggaa ttcgttgctt attcagaaga agaaatacaa gaaacagatc tttacggcgt
     2701 tgttatcccg aaagatagaa agctcaacca atttaaagta tatgcagcag cagagggagt
     2761 tcgtccagtt gacggaagta ttgtgctgat cgaactgacc cattaccctg aaaaagggta
     2821 tgcgactagt ttagaaggga taatcaagca agtgattggt cataagaatg accctggcat
     2881 ggatatcctc tcaattgtcg tggctaatgg tatccctacg aaatttcctg atgatgtatt
     2941 gtctgaagca gatgaagttc cagatcaaat cagcgaaaag gatataactg gacgtagaga
     3001 tttaagaaat cagctcattg ttacgattga tggagaagat gcaaaagatc tagatgatgc
     3061 agttacggtt aaaaaattag ataacggtaa ttattttctt ggagtacaca ttgcagatgt
     3121 ttcttactat gtgacacaag gcagtcaatt ggacagagaa gcatatgaaa gagggacaag
     3181 tgtatatttg actgatcgag tgattccgat gatcccgcaa cgtttatcga atggtatctg
     3241 ttcactgaat ccccatgttc caaggctgac catgagttgc gaaatggaga ttgatccaaa
     3301 tggacaagta gtctctcatg atattttccc aagtgtgatc caaacaacag aacggatgac
     3361 ctacacagct gtcaatcaaa tcttagaaga tcaagacgaa gaaacgatgc aacgctatgc
     3421 tcagctcgta cctatgttcc aagaaatggg tgaattgcat cgaatccttg aaacgatgcg
     3481 aatcaaacgt ggcgcgattt cttttgagga tcgcgaagcg aaaatccttg ttgatgctga
     3541 aggacaccca aatgacatcc agctaagaag cagaggaatt ggtgaacgct tgatcgaatc
     3601 tttcatgctt gcggccaatg aaacggtagc tgaacattat aataaattaa atctgccgtt
     3661 tatttaccga atccatgaac agccaaaaga agaaaaaatg cagcgcttct ttgattttgc
     3721 ttcagctttg ggcattctgg tccgaggaac gaaaggaacg atcacaccaa aagatttaca
     3781 gcatgtgatc gaaggagtag aagacaaacc agaagctgca gttatcaata ctatgttgct
     3841 aagaagcatg caacaagcac gctattcaga agacaatttt gggcattatg gcttagcggc
     3901 agattactac acacacttta catctcctat tcgacgctat cccgatctaa tcgtccatcg
     3961 tctgatccgt tcttacagtg aagataaaag tgaaagcaat caaagttcgt gggctgcgga
     4021 acttcctgaa attgcagatc atagttctaa gatggaacgt cgtgcagtag aaacagaacg
     4081 tgaagtagat tccatgaaga aagcagaatt catgatggac aaagtgggag aagaattcga
     4141 tgggatcatc agctctgttg tgaaattcgg cctgtttatc gaactgccga atacagtaga
     4201 aggattgatc catatcaatg aattgaaaca ggactacttc cattttgttg aaaatcattt
     4261 agctcttgta ggtgaaagaa ctggtctgac ttttaaaatc ggacaaaaag tgcgcgtaaa
     4321 agtagtcaaa gctgatccag atgaacgagc agtggatttt gaactcgttt ccgcagaaga
     4381 ggtcactgcg ttggaacgtc caaaagcacg caatggaaaa tctggaaaac gagaaggaaa
     4441 acaagcaggc aaacgctcag aaaaaaatgg caagaagaac aaacgatata gtgatagtaa
     4501 gcaaacgttc ggtaagaaaa aagggaaaaa gccattttac aaagatgtca aaaagaagaa
     4561 aaagaaaaaa taaaatgagt tggaggaaac agctatgcca aaaggcgagg gaaaactaat
     4621 tgcacaaaac aagaaagctc gccatgatta ttcgatcatc gacacgatgg aagcagggat
     4681 ggtcttgcaa ggaacggaga tcaagtcgat acgaaacagc cggatcaatc tgaaagatgg
     4741 atttattcgc gtccgcaacg gggaagcttt cttgcataat gttcatatca gtccttatga
     4801 acaaggaaat atttttaatc atgatccgtt gcgcacgaga aagttattat tacacaagaa
     4861 acaaatcgtt cgtcttgaaa acgaattgaa aaacactgga atcactgttg ttcctttaaa
     4921 agtctatatt cgtaacggct atgccaaggt attgattggt ctggcaaaag ggaaaaaatc
     4981 gtatgataaa cgggaagatt tgaaacgaaa agatatcgat cgacaaattg atcgaacatt
     5041 aaaaaatttc tctagataat ttcattatcc tttttcgcat attcggtgct tttgctttta
     5101 cttaatgata aaatttgtta gcatttaatc tgataaaaca tgattatcac aggttttttc
     5161 ttagatcagg agcaccgtgc atggggaaaa attcgcttcg tttttgactg aaataaaaaa
     5221 gtgtctaatt ttcatgaaaa tgttttgaat tttctgtttc atggtggtat gataccgtgt
     5281 ggttagaaac cgattggaaa aaaccagata cgcacatgaa ttgattttat gtgaatttcg
     5341 gggaaaagag gtgaaatgga ttggatgaac gctcgctaac gtttcacatt ggaccaattt
     5401 ggtttgatgg tacagtttgt ataatggtgt tactgacctg tttgattgtt ttcttcttag
     5461 cttacttttt tacaagaaat cttaagttga aaccaacagg caaacaaaat gcgatagaat
     5521 gggtcattga ttttagtcga ggaatcgtaa cagataatct gcctagaaaa gaattgagca
     5581 atttccattt gttggcattt acattgtttt tatttgtttt tgttgcaaac aacataggtt
     5641 tagtaacaaa aatcgtctta cctaacgaaa caacactttg gaaaagcccg acagcagacc
     5701 cgtttgttac tttaactttg gcatttataa tgatcttact tactcactta ttcggggtga
     5761 aaaagttagg cttcaaagga tatttcgtaa attcgttctt gaaaccctat agttttatgt
     5821 ttccgatgaa actgattgaa gaatttacaa atttattaac acttgcttta cgtctttatg
     5881 ggaatattta tgcgggggaa gttttgctaa ccttgattgc aaaaatgatg acaagcttag
     5941 gctggttctc attaccatta gcaattccat tagagatggt ctggatcgcg ttctccttgt
     6001 ttattgggag catccaagca tttgtctttg tcactttgtc aatggtttat atgagccata
     6061 agattgaagt agaagaataa tactcggtta aaaaacaaac tactatttat ctattttagg
     6121 aggaaaacaa ttatgaatta tatcgcagca gcaatcgcaa tcatgggagc agcaatcgga
     6181 gccggttatg gtaacggtca agttatctct aaaacaatcg aatcaatggc tcgccaacct
     6241 gaaatgtctg gtcaattccg tacaacaatg tttatcgggg tagctctagt tgaagctgtt
     6301 cctatcttag gggtagttat cgccttgatt ctagtttttg ccgtttaatt gaatcagtat
     6361 taaggcagaa acaacatcgt ttgttactgc ttttttacat ggaaactaga aatactccaa
     6421 agaaaggaag gctcgcctat gctgaatcaa ttggcaattg cagaagttgg caatgcgatg
     6481 ttaggtaata tcatcgttgt cagcggctca tttttgatac tactggctct cttgaagcac
     6541 tttgcttggg gaccaatcag cgatattttg aaaaaacgtg aagacaagat cgccaatgat
     6601 ttagattctg cagaacaatc tcgcatcaac tcagcgaaaa tggaacaaga acgcgaacaa
     6661 caattgttag cctctcgttc tgatgcagct gatatcatca aaaatgcgaa agaaagtgga
     6721 gaattaagcc gccaaaatat tttgaaggat gctcaagaag aagcagctcg tctaaaaagc
     6781 aaagcccaag ctgatatcac tgtagaacgt gattcagcgc tgaactctgt aaaagacgac
     6841 gttgcagaac tctctcttca aatcgcggaa aaaatcttga acaaagaatt atctccagaa
     6901 atgcatgaat cattaatcaa tcaatacatt gaaggtctag gttcttcaaa tgaaactaga
     6961 taaatataca gtaggaagac gttacgggaa agctttattt gaactggcga tcgattcaaa
     7021 tcaagcagaa gaaatctatc aagatctcgt aagtttacgt caaatctatg aacaagtacc
     7081 tggattaggg aatatgttaa gtgatgttcg tctagaacct catgaaaaac gagaaatcat
     7141 ggacaagctt gtcagcggtt atgatgggat cgttaaaaac tttttagaag ttgtttatga
     7201 gtataaccga atggatgacc ttttgttcat gatcgaagaa tatgaacgtc gatatgatga
     7261 acatcaaggg ttactattgg gaagtgtcac aacagcagtc ccactttcag acgaacaacg
     7321 aatacaatta gaaaagaatg ttgcaaaaac aatggactat caatcagttg aattaaaaca
     7381 aatcgttgat tcttctatta ttggtggcgc gattgttgaa gccaaccatc gagtaatcga
     7441 cggaagcatt cgcacgcaat tagaaaaaat gcgtaatcaa ttaaacagat agtacaaaga
     7501 ggtaggtgaa tcgaatggcc atcaaagcag aagaaattag tgccttgatt aaagaacaaa
     7561 ttgaaaatta tcaaaacgtg ctttcagtcg aagaaatcgg taccgtaact tatgtaggtg
     7621 acgggatcgc tcgtgcacat ggtttagaaa acgcgatgag tggtgagttg cttgaatttt
     7681 caaacggctc atacggaatg gcgcaaaact tagagtcaaa tgatgtaggt atcattatcc
     7741 ttggcgattt cgagtccatt cgtgaaggag ataaagtaaa acgaacaggt aagatcatgg
     7801 aagttccagt tggagaggcc ttgatcggtc gggtagtcaa tccgctaggt caaccaatcg
     7861 acggactagg tgaaatcgtt actgacaaag ctcgtccagt agaagcgatg gcaccaggtg
     7921 ttatgcaacg taaatctgtt aacgaaccaa tgcaaacagg gctaaaagcg atcgacgccc
     7981 ttgtgccaat cggacgcgga caacgtgaat tagtcatcgg tgaccgtaaa acagggaaaa
     8041 cttctattgc gatcgatacg atcatcaacc aaaaaggtca agatatgatc tgtatctatg
     8101 tagcaatcgg acaaaaagat tctacagttc gtacacaagt tgaaacattg aaaaaatatg
     8161 gcgcaatgga ttacacaatc gttgtgaatg ccggtgcgtc tcaaccagca ccattgcttt
     8221 atatcgcacc atatgctggt actgcaatgg gtgaagaatt catgtacaac ggtaaacatg
     8281 tattgatcat ttttgatgat ctttcaaaac aagctgttgc ttatcgtgaa ctttccttgc
     8341 tacttcgccg tccaccaggt cgtgaagctt atcctgggga tgttttctac ttgcactcac
     8401 gtttattaga acgtgcagca aaattaagtg atgatttagg tggcggttca atgactgcct
     8461 taccatttgt tgaaacacaa gctggagata tctctgctta tatcccaaca aacgttattt
     8521 cgatcactga tggacaaatc ttcttagaaa gcgacttgtt ctacgcaggt actcgtccag
     8581 cggttgatgc cggactatct gtatctcgtg tagggggttc tgcgcaaatc aaagcaatga
     8641 aaaaagttgc tgggacttta cgcctagact tagcaagtta ccgtgaatta gaagcattta
     8701 cacaattcgg ttctgacttg gatgcagcaa cacaagcaaa actaaatcgt ggacgccgta
     8761 cagtagaaat cttgaaacaa aaattgcatg caccgctagc tgttgaaaaa caagtagtga
     8821 ttttgtatgc tttgacacat ggattcttag atagtatccc tgtagacagt attttagact
     8881 tcgaacatga attattcgaa tatctggata ccaatcattc agatatcttt gaaacaatcc
     8941 gtacaacaaa agatcttcca gaagaagaag cgttgaacag tgcgattcag gaatataaag
     9001 acatgttctt agctacaaaa ggaagtaatt cctctacaga agataaattg aaatccattc
     9061 aaaatgcata gtgaggtgag atgaatgggt gcttcattaa atgaaatcaa gacacgtatc
     9121 gcttcaacga aaaaaacgag ccaaatcacg cgggcaatgc agatggtgtc tgcttctaag
     9181 ttgacaaaat ctgaagcttc ttcacagaag tttcaggttt atgcaacaaa agtaagagaa
     9241 atcgttacgc atttgactgc tactcagtta aatgatattg cctcagaaaa tcctagaggg
     9301 gatatcaatt acaacagcat gctgctcagc cgtcctgtga agaaaactgg ttatatcgtc
     9361 atcactgcag atggcggttt agtcggtgga tataacagct cgatattgaa acaaacgatg
     9421 tctattttag aagaagacca ccaatcaccc gatgattacg tgatgatcgc aattggcgga
     9481 actggtgcag acttctttaa agcacgcggt atcaatctag catatgagct gcgcaatcta
     9541 tctgatcagc caagctttga tgaagtccgc aaaatcgtaa atatggcaac aactatgttc
     9601 caaaacgaag tattcgatga attatacgta tgttataacc atcatatcaa ttcgctaact
     9661 agtcagtttc gtgtagaaaa aatgctgcca atctcagact tagatccaga agaagcaacg
     9721 actttcgaac aagaatatat ttttgaacct tcaaaagaag aaatcttgtc tcagttattg
     9781 cctcagtatg ctgaaagttt gatctacggt gcgatcgttg acgccaaaac agcagaacat
     9841 gctgctggta tgacagcaat gaaaacagca actgataatg ctgctaatat cattgatgag
     9901 ctgacggttt cttataaccg tgcaagacaa ggggctatta cccaagaaat taccgaaatt
     9961 gttgccggag cttcggcact agaatagtat tgagattgga ggaaaaaaga tgagttcagg
    10021 caagattgtt caagtaatcg gtcccgttgt cgacgtggaa ttttctttag accaatcctt
    10081 accagatatc aacaacgcat tagttgttta taaaaatgac gaaaataaat caaaagttgt
    10141 tcttgaagca gcgttagaat taggggacgg agtgatccgg accattgcga tggaatcaac
    10201 agatggttta caaagaggaa tggaagtcat tgatacaggc aaagcaatct ctgttcctgt
    10261 aggtaaagaa acattaggtc gcgtattcaa cgtactagga gatacgatcg atttagaaac
    10321 acctttccca gaagatgcgg aaagaagcga aattcataaa aaagcaccag cctttgacga
    10381 attaagtaca agtacagaaa ttttggaaac agggatcaaa gttatcgatt tgcttgcccc
    10441 atatttaaaa ggtgggaaag tcggactatt cggtggtgcc ggtgttggta aaaccgtact
    10501 gatccaagaa ctgatccata atatcgccca agaacatggt ggtatttctg tatttaccgg
    10561 tgtaggtgaa cgtactcgtg aaggtaatga cttgtattat gaaatgaaag attcaggagt
    10621 tatcgaaaaa acagccatgg tgttcggaca aatgaacgaa ccaccaggtg cacgtatgcg
    10681 tgttgctttg actggtttga cgattgcgga atatttccgt gatgtagaag gtcaagatgt
    10741 actgttgttt atcgacaaca ttttccgttt cactcaagct ggatctgaag tatcagcctt
    10801 gttaggacgg atgccttctg cggttggtta tcaaccaaca ttggcaacag aaatgggtca
    10861 attacaagaa cgtatcacat ctacgaaaaa aggttcgatc acatcgatcc aagcaatcta
    10921 tgtgccagcc gatgactaca ctgacccggc gccggcaaca gcattcgccc atttggatgc
    10981 gacaaccaac ttggaacgta aattaacaga acaagggatt tatccagcgg tagatccatt
    11041 ggcttcttct tcaagtgctt tagcacctga aatcgtgggg gaagaacatt ataaagtagc
    11101 aacagaagtc caacacgtat tgcaacgata tcgtgaatta caagatatca ttgctatctt
    11161 aggtatggat gaattatccg atcaagaaaa agtgttagtt tctcgtgccc gcagagtcca
    11221 attcttcttg tcacaaaact ttaacgtggc tgaacaattt actggtcttc caggttcata
    11281 tgtccctgta gaagaaacag tgaaaggatt ccgcgaaatc ttggaaggca aatacgatga
    11341 tcttcctgaa gaagctttcc gaagtgttgg ccgaatcgaa gacgtcgtag aaaaagcgaa
    11401 aacactaggc tactagaaag gggtgcccca tggatcaata tttaacagta aatgtggtaa
    11461 ctcctgccgg tttggtctat gatcaccatg cagctatcgt cgttgcacgt acgacagctg
    11521 gtgagcttgg gattttgcct aaacatgcac caatcatcgt tccattgacg attgatgaag
    11581 ttcgtgtaaa acgaacagat tcagataccc acgtcgattg gatcgctgtt aatggcggaa
    11641 tcatggaagt tcgtgataat gttgtttcaa tcgttgctga tagtgcggaa cgtgaacgtg
    11701 atatcgatgt atctcgtgcg gaacgtgcaa aacaacgcgc agaacgccaa atcgaagaag
    11761 caaaagcaaa acaagatacg aacgaattga aacgggcaac tgttgcgttg caccgagcaa
    11821 tcaatcgtat caaagtatct aagcactcat aaaatgagat gcggatgttt atccgtgttt
    11881 aagaacagta aaaagaggtt atgacagaag tggtcagctt caagacataa gaaggaattt
    11941 acgaaaattg cttctcaaat ttttgtgaaa tctcagctta tttttcgaag aagctacttc
    12001 tggaacaccg tatatcagag gttgtaaaat cagcgttttg tcctgagtat tagagaaaca
    12061 aatggaaaat agttcctcat attttgccgt tttttgagct aataccgagg gtcagatgat
    12121 tgaacaccgt ttattt
//
LOCUS       DAZULR010000065        11445 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.067, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000065 DAZULR010000000
VERSION     DAZULR010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11445
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.067"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            185..1183
                     /locus_tag="ACG8ZV_002367"
     CDS             185..1183
                     /locus_tag="ACG8ZV_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFS4997642.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            1295..1804
                     /locus_tag="ACG8ZV_002368"
     CDS             1295..1804
                     /locus_tag="ACG8ZV_002368"
                     /EC_number="3.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HFS4997643.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(1834..2493)
                     /locus_tag="ACG8ZV_002369"
     CDS             complement(1834..2493)
                     /locus_tag="ACG8ZV_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HFS4997644.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(2495..3259)
                     /locus_tag="ACG8ZV_002370"
     CDS             complement(2495..3259)
                     /locus_tag="ACG8ZV_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HFS4997645.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(3267..3944)
                     /locus_tag="ACG8ZV_002371"
     CDS             complement(3267..3944)
                     /locus_tag="ACG8ZV_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HFS4997646.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(3981..5366)
                     /locus_tag="ACG8ZV_002372"
     CDS             complement(3981..5366)
                     /locus_tag="ACG8ZV_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HFS4997647.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(5576..5660)
                     /gene="ffs"
                     /locus_tag="ACG8ZV_002373"
     ncRNA           complement(5576..5660)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACG8ZV_002373"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5683..6198)
                     /gene="tadA"
                     /locus_tag="ACG8ZV_002374"
     CDS             complement(5683..6198)
                     /gene="tadA"
                     /locus_tag="ACG8ZV_002374"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HFS4997648.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            6305..7162
                     /locus_tag="ACG8ZV_002375"
     CDS             6305..7162
                     /locus_tag="ACG8ZV_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4997649.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYRYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDGTEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(7243..7578)
                     /locus_tag="ACG8ZV_002376"
     CDS             complement(7243..7578)
                     /locus_tag="ACG8ZV_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997650.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(7645..9015)
                     /locus_tag="ACG8ZV_002377"
     CDS             complement(7645..9015)
                     /locus_tag="ACG8ZV_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HFS4997651.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(9093..9629)
                     /locus_tag="ACG8ZV_002378"
     CDS             complement(9093..9629)
                     /locus_tag="ACG8ZV_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFS4997652.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            9938..11419
                     /locus_tag="ACG8ZV_002379"
     CDS             9938..11419
                     /locus_tag="ACG8ZV_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4997653.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
BASE COUNT         3516 a         2300 c         1856 g         3773 t
ORIGIN      
        1 atttgcatac ttcataataa taataacata atacctaacc tctcgtaaaa atactagatt
       61 tgttttcttt tatttttcat cactagatac attctataac ttaccgtttc gatttcgaat
      121 tcaaacattt ttgagaagca ttctcaatta aattctgcta tagtgtgaaa agggaggaat
      181 ttttatggaa atctatgaca ttacaatcat cggtgcaggt cctgtaggga tgtttgccgc
      241 tttttacgca ggaatgcgcc aagctaaaac aaaaatcatt gacagtctac ctcaacttgg
      301 tggtcaatta gcaactttgt atcccgaaaa atatatttac gatattcctg ggtatccagc
      361 aataaaagca agtgaattaa tcgatcaatt agaaaaacaa ttaactactt ttaaccatac
      421 attccattta aaagaagaag ttctctcgct tactcgtgaa gacgaagtta tcgagattac
      481 tacaaataaa ggcatccatt attccaaagc agtcatttta gctttaggaa atggttcatt
      541 ccagccaaga aaattgaatt tagataatgc tgaatcattt gaaaaccacg gattggatta
      601 tttcgtgaat gatttgatga agtatgctgg aaaaaaagtc gctattgctg gaggtggtga
      661 ttctgctatc gattggacgt tgatgttaga gcctattgca agcgaagttt acttgattca
      721 tcgtcgcccg gaatttcgtg cgcacgaaca tagtgtatca cgcttgaaat cttcatctgt
      781 caacttgctt actccctatc tcatcgatgg attatcaggc aataatgggg aactgacaga
      841 tatccggtta aaaaaagtga aaagtgacga gacgattgat ttgatgattg attctctgat
      901 cgtcaattat ggattctctt ctaatttaga acatctttct tcttggggac ttgatagtac
      961 cagaaatgcc attactgtaa aatcagatat gtctacttct attccaggcg tttatgcagc
     1021 tggtgacatc tgtacctatg aaggaaaagt gaaactgatt gctactgggc tcggtgaagc
     1081 acctactgca gtgaacaacg ctttacacta tattaatcca aaggaacgaa ctcagcctgg
     1141 tcacagcaca agcttatacg ataaaaatct tcgtcctagt tgatttttta tatctctttg
     1201 catttcaagt taaacccgaa agcagtttct tgcatttttt tcatgttccg ttaacatgaa
     1261 atagagaaag aaaaaataaa gggggagcaa taatatggtc gtcaaaactg agactttaga
     1321 agaaaaggca agagaactat tgaaggaacg tggcgtaact gtagaagata tcgcacaact
     1381 tgtcatgttt ttacaaaaag actatatttc tgatttgact ttggcggatt gtactgaaag
     1441 tgtcaacagc gtgctaacaa agcgtgaagt acataacgcc attatcactg gaatccaatt
     1501 agatatatta gcagaaaaga aaaaattgat gagtccgttg caacatatta tcgaagatga
     1561 cgaaggcctt tacggtatcg atgagatcct agccttgtca atcgtgaatg tttacggtac
     1621 gatcggcttt acgaattatg gttatatcga caaggtgaaa cctggtattt taaaagaact
     1681 aaacagccac gatggcgttc atgtccatac cttcttagat gatatcgtcg gagcgatcgc
     1741 cgctgctgct gccagtcgat tagcacacaa agaaccagaa aaaagaagtc gccttactca
     1801 ataattcaac aaaaaaagaa agaaaacgtc tatttagacg agttctttct tttttgtttg
     1861 tttcaagcta ttttttccta agaaaagaaa aacagcaaaa aataattcta ataatacaaa
     1921 aaataagata aagctatgca tgaaaaattc ttctggaagt acattgatga ttggatcagt
     1981 aacgggatcg aataaccagt catcgttgtt gaaaaacgtt tcatgaaaaa ggataaaaaa
     2041 gcgatcaaat cctatcatca tgaaaaaacc gaaaacaact ggcagtaaca tgccgatttg
     2101 aaacggacga atcaaccgcc aaagccgatc attcttttgc aaatatttga taaacaaaat
     2161 actcgggatc aaagtgatga aaaacacagc ataatccact aaaaacaaaa ttttcacttc
     2221 ataaaagtga tgggctccgc tagcagaaac tgggaaatct ggcaagctga ggatggtttt
     2281 gaagggatta ttgagataat tcattaggtg atcaaaattt ttcagtaacg tctcttgatc
     2341 taaagaagta taatccaaaa tttgcaaatg tccgatatca aatacgtata gtggtcgaaa
     2401 gttgatcgtc acaccaactg ccagactgat cagtgtcaga aataggctga acaatccagc
     2461 atattccatc cactgccatc tcgaattttt catattagaa gctccattca tccagtgatt
     2521 gtttcacata ggtagctggg ataggcaacc caggtacatc ttcttctttt gtaaaacctg
     2581 ataaaacgag caaagtatct atattattgc gtatcccagc ttggatatct gtttcatagt
     2641 tatctccaac catgattact tcttcttttt gcagccctaa tacttcaacg gctttatcca
     2701 taatgatggc ttctggtttt ccgatgtaga tcggcggcgt ttgggttgct gtctctacaa
     2761 aagagatgac tgaccctgct ccaggaagaa ggccgcgttc agtaggtata ttcttatctg
     2821 ggttcgttcc aatgaaagta gcaccttttt gaatagcaag tgttgcttta actacttttt
     2881 cataggtcag ataattatct aagcctacca ctacatagtc aggagcctct tcttcccatg
     2941 taaatccggc agctaaaatc aagtcaatca atcctgcttc tccgataaca tagacttttt
     3001 tcccttttcc atctgctttc ataaaatcga ttgttgccaa agtagctgtg tagactgtct
     3061 ctggagctac atgaatgtca aactcatctg ctagacgatt agctactgtt tctggtgact
     3121 tagtcgtgtt attggtaaca aacaagaaag gtaattttct tttttgcaat tcttccacaa
     3181 atcgtttacc ggccggtatg ggttgtgtcc cacgataaat cgttccgtct aaatcaatta
     3241 aatatccttt atagtccatt catccactac tcttcccttt ttctgatcgt aaatgctgtt
     3301 tttgtttttt ctacttgttt aggttgttct tgttttttta ctttttcaga ggtttttgct
     3361 gactctgttt ttcgattttt aataaccggt tttttgcgat tagatgcgac tggtcctttt
     3421 ttctcatcga tatacgcacg attatggttt tttttctttt ttcggcgctg agttgtcttt
     3481 tcttttttac cgccgattct ctcgatgaca aaatacgcac aaccaaaatt gcaatattcg
     3541 taaagatagt cttccaagga atcgattcgc tgatctggat gcgcccgtcg attatccgct
     3601 tggaaaaatc cttttaggcg tagttgttca taaccccaat ctcctacgat ataatcatat
     3661 cgggctagta catcactgta acgttctcca agcttttctg cattaaatcc ttcacgataa
     3721 tcggacacaa gccgataatg tctttcacct atcaaaaaat tactgtcatc taacagtgtc
     3781 actagctcgc ctttgacttt ttctgcttta ggctcctcaa cgatttcttc caaagcagct
     3841 gtcagttctt cggtgactgt tgtttcctgt tcagctgatg attttttctt agcaatttct
     3901 gttttatgct caacgttctg ctgttcattt tgttttgcag acatgcgttc accacctatc
     3961 ttttttatta taccttgttt ttatttgatt gggtagtgag ctttcaagta atctcctacc
     4021 acacttcgga taaattcagg gaacaaaaat tcattttttc cagcaatctc aatcgttgga
     4081 aaaaatggaa caaacatcaa atgatctacg gtagtaaaag tataattttt attcagatcg
     4141 attggcttgt tcttccaaaa gacttgatgg ttaatagaat catatgtgat tccattatag
     4201 accatctgcc caaaaatctt accgcgaaat cccattccct tcataggata gttacgtaaa
     4261 aagttacgat ttttttctat ttctaaaact aagcggatca gatcatttcc acccaatgtg
     4321 acatttaaca agtgcatcgg atgcggcaac gcagtgtgaa gctgatcctg attgacccgc
     4381 ccttttggaa tttcagttaa aaacagacca ctgtttaata ttgctgcttc cgtctttcct
     4441 cgttctttca ccgcctcaaa ggctacttgg ataaacgaat gctcattgaa gatatctaga
     4501 ctcagagaaa atggcaaatc tgctacttct ttttctttta ataattcatg cccacgttct
     4561 agataactat ttatttcttg ttcatcttct gtaaaagctg tcattgtttc ggtagggatg
     4621 gctttggctg aatgcttaag gatttttttc tcttcatcga tggttaaatg gacttcaccg
     4681 acatactgcc cgtactttcc agcggctgct atttggacat cattgattac gtgaccttct
     4741 ctgaataaat gatgggtgtg cgatcctaaa ataacatcaa ttgctggtat ttcttttgca
     4801 atttggaaat catcctgaat cccgagatga ctcatcaaaa ctaaaacatc cacttgtgaa
     4861 cgtaaatctt cgactaattc tggcaaaata tcataaggat tccgtatgtc ccagccattc
     4921 ggattataag taagcggaaa tggagcagta aatgcaatta gtccgatttt cgtctggtgt
     4981 ttcgttgtaa tgattttata tggtttcgtc catgccggtg gctggagcgt atttttatcg
     5041 aataagttat ccaggatgat atcaaactca gcatgatcgt ataaatgatt caactcttct
     5101 ttggaatttc ctacgccttc attgtttcct atcgtcgctg catcataacc aacttcattc
     5161 atcagcaaga tattttcctg tccattcgtt gcttctgaca atggatgcca acgatccaca
     5221 aaatcaccta gatctactgc aatcgttgtc gttttttctt tcttttcgtt ttctcgttta
     5281 cgttgatcca aaaaccttct gatccttggc caattttcta aatgagaatg cagatcattc
     5341 gtatgtaaaa tcactatttt ttccatgtac cctctcgcct ctctttatct ttatcatacc
     5401 ataggcagct ttttcttcca ttgaaacaag ctctatttca gagtttttcc tgccttgaag
     5461 caaattgtat aagtacaata ttcgataaat cagtctggct aaaaaatcag gaacattcat
     5521 ttttacagta ctataaaaat aaaaaaaaca gacccgaaag tctgttgtcg tttcattata
     5581 atcagacaca tggcggaacc tgcttagtgc tgcttccttc cagacctgac acgcttcaca
     5641 agcccaccat tgtcctagcc tttcggcaaa gaatagtata ccttattttt cattcgttga
     5701 ccagtctttt tttaatttct tttttcgctg gcggagcttt cggaaaaagt cagtcaaaat
     5761 catcccacat tcgtcttcta aaatgccacc ttctacatat gcttggtggt taaaccgctc
     5821 gtcctccaaa agattcatca aggtaccggc tgttccgcct tttggatcat acgcgccgaa
     5881 ataaacttct gctacacgag acaaaatcat cgcgccgctg cacataggac aaggctctaa
     5941 ggtaacaaaa agtgcagcat cttccaagcg ccagcttccc actttttcac aggcttcctt
     6001 gattgcaagc atttctgcat gtgtagtagc atcttgcgtg gtttctctaa ggttatatcc
     6061 tcttccaatc acttttccat ccaatacaac cactgctcca atcggaactt catgaagcat
     6121 ttctgctttc tttgcttctg ccaatgcaag gcgcatccat ttttcttttt ctactgcatc
     6181 aagatttgta tttaccaatt acccttccct gcctttgttt tttcttgttt tactttagca
     6241 tatgataaaa aggctgtaac taactttttt ttctatggta aaataaatac aagaggtgaa
     6301 caagatgaaa atggataaat tacttgctct ttacccacaa gcacagaaaa aaaactctcc
     6361 agcatcagaa gcggatatcc tttcttttgc aattgatgat gcttttatct ggatcaaaca
     6421 agattcatta tctcaacaag aaaccagcct tttgaaagcg ttattccctg taatcaacga
     6481 tcaaaaaaaa cacccatggt atcgctatct ttttaaagat gcttcttgtg ttcaagaaaa
     6541 aagctttcgt ttgatccagc ttcacgtcga atcaaaagga gaattcttaa aaaaagaatg
     6601 gcaagatact attttggaat tatttcgcta ttctgctgat ttcttttttt atacagacac
     6661 agatgcgctc ttagtcgaac aaataaaccg tgattatctt gatggtactg aaatcaacgg
     6721 tatttttcta tctttagatg ctgattttga tacgacaacg tctgtattcg ttggttcttt
     6781 ccattcacct ggcaccgacc tcgtcccttt gtttgctgaa gaaagaaaaa tttttttaac
     6841 agagcaaaac aatctttata ctcacagccg tactttttct atgcaagatg tggctttaca
     6901 ttactataca aaagatactg taaaagatag taagttgatc aaaagttaca tagaactgat
     6961 caaacaaaat gaaatggaag tgatcattca agaattatgg aatgaattag gcaatgtcag
     7021 ctctgctgca aaaacactgt ttcttcatcg taatactcta aaatatcgaa tcgaaaaatt
     7081 tcaagaacag tctggtttca atctaaaaaa agccaacgat ttactgtttt gctatctttt
     7141 attgcttcat gaacataatt aaagatagat taaaggggtt gtgacaataa ttttgtcaca
     7201 accccttatt tcgaatgaat agtgttcaaa agctagtttc tcttacatca ttttttcaac
     7261 aaaatgcatt agccggtctt ttacatcttc ggttgaatct ttgattgaat caccataaac
     7321 agagattttc ttttttcctg atttgatttt tgctaacatt cccatcaaag aatccaagtc
     7381 actatctgaa agaccatcta cgatttctag taatttttca tttccatcaa atttgtcata
     7441 gacgaatttt tttactttcg tccgagtagt catatgatgg atcttttcca ttacttttcc
     7501 cgatacaacg actgctgtcg ctacactggc agcggctgct acgcttaatc cgattgttac
     7561 ttttgttgat gttttcataa gtatcagctc ctttttatct atctccatca tagcatagac
     7621 aaaaaaataa acgaactaat ccactcagtg aaatctcaat cctttaggga aaaagttctt
     7681 tactgttcct tttacttgtt tcccaaatcc gacaggtatc ttatctaata ctagcaaaac
     7741 ccatccttga ttcccatcac gttgaaatgt ttctcctgct gtgtaagatt gccattcctt
     7801 ttgagtgatc ggcaagcaag gtatattctc tatctttttt gtagcaagcg ctaatgcata
     7861 gctaggttca aatcgattct ttttgaaatc tcctaaatgc aaacctgtac gtacgacttt
     7921 taaaccatcg agagaagggg ctaactcagg aacttcccaa agatggtcgt tgaacactaa
     7981 aagtcttcca gtagcttcat aatgaaaatc atttgaaaac tccgtccaga gtttttcctg
     8041 ctcttttgtc atttgcactt tacttttttt tcgtgtcttc ttttctttat gcatctgatt
     8101 ttgtccatga aaagtcagct ttgcaacaaa atgtccttca ccctgatctt tatgaggcca
     8161 tatacgtatt gttttttcca aaccagctac gcttccccat tcagaacgtc ctgaactaac
     8221 ggattgagtc aaaggaatct cctcaatcgt tactggataa ttttctacaa gccagctaat
     8281 gatctcttca ttttcttctg gtgcaaacgt acaagtcgaa taaatcagtt gtcctttatt
     8341 ttttagcatt tttattgctg aagacaaaat ctcttgctga cgtttttgac agtatagcgg
     8401 agattcttct gtccactctt ttattgcatt tggatctttt cggaacattc cttctcctga
     8461 acaaggagca tcaaccacga tccgatcaaa aaagcccgaa aaatgaggga caagttctgc
     8521 gggtgcatga tttgtcacta ttgcgttcga aactccccat cgttctatat tttctgataa
     8581 aatcttcgca cgtttcggaa agatctcatt cgtcactaat aaccctttcc ccttcatttg
     8641 agcagctaat tgggttgatt taccaccggg agccgcacac aaatccaaaa ctttttcacc
     8701 gggttttgct gcagcagctg ttccaacgat cattgcactt ggttcttggc tatattcata
     8761 cccagcttga tggaggaaag actttccatt gacagtgcca agaaatccct cattgctgta
     8821 gggagcgggt tgtaattctt cgctatggta agtttggacc atgtccaatc ctgccggttt
     8881 tagtggattc caccgaaatc cttttttcac gcttccttgt tcaagcgcag aaaaaaaatc
     8941 ggatgcttct tcgcctaaaa gaagacgata ttttttgata aattgctgtg gtaacgttgt
     9001 cgcttcctcc ttcattccaa tgtttcgtta gacattttac aatctttttt acgaaaaata
     9061 aaggtggctg atctactttt tcatgttgct gcctaaggtg actgttcctt taagatattt
     9121 tccaagtatt catccgtcac ctcgttttta tcccaaacag cgttcatcat ttcaagaaaa
     9181 tcttgagaag aatcatctga gcgcaaactt cccaatgcat taagccatac caattcaagc
     9241 gacttttctt ctttgatctt cgtgtgacct ttgacatatg agaaaaatgg ccgcttaaat
     9301 agcgaatcca tgtctaaatc agattttgca atgatttcac gaatactttc atggatagaa
     9361 aaaaaatctt tcaataagta gacaatgctt aaaacatcat cggaactgca ttcagctaag
     9421 tagttttcaa aataaacagt gatttcttct aatatcttct cttttaaccc gctgattgat
     9481 ttgaaatgtg tataaatcgg gtatgtagaa caaccgcaga actctgctaa ctctcttgca
     9541 gtaattgact tcattccata ttcttccacg tataccatac ttttgaacag caaatattct
     9601 ttactataat ttgttactct ccccatcatt cttacctccg tctcttttca tctacccata
     9661 aataaatagc ataaataatt ctaaaaatat tattgataat tatcaaaaca tatttagtta
     9721 tatccattaa aaatcaattt ttccgcctta aaaacaagaa tatcttgaca aaatacccta
     9781 ggaaataaac aatagaataa acaaggtaac aaaaaaatta aataacgtta tataaaaaag
     9841 aaggcgacac tctgtgagaa taacacagac tgaaatgact ttccactcac agtttttgtc
     9901 taactatata caaaaacaga ataaaaagga ggtatttatg ctaattgaag caagaaaaaa
     9961 agagttactt gttctacaaa tggtcattca aaaaaataat tgttctttac aagaattatc
    10021 caatgactta catattccaa aacggacaat caaagaactg atccgaaaaa taaatgtatc
    10081 actcaagcaa tttttattga ttgatgaatt tatttattct aatcataaag gagagatcca
    10141 aaccaaagaa accgatcaaa ctaaaaagtt agctgttttt tctaagttaa aattatgcta
    10201 cctaaaagaa tccaatcgtt ttaactattt gatgttacta atcaattatc cacaaactgc
    10261 tgtaccaaaa aaatatttac ttgaacaact ttatatatcg ccctcctatc tcgaaaaact
    10321 gacaaaacag ctcaatcatt ccttaaaaaa attccattta cggatcctat ctgtaaaaaa
    10381 ttgctgtact cttgaaggaa atgagttatc tatccgtctc tatctttact tttttctttc
    10441 agatacattt ggaggtaacg attggccatt ttcctcactt gaattaaatg cactaaaaat
    10501 gaacagtaca gatgagcaaa tagaaaaaat ttcaaaacaa gaaaaaaata tctacttgct
    10561 gttaacttta ttcatattac gaaacaaaca acaggcatat tttccaaaaa cttcttctga
    10621 aatcactgaa ttgatggact tattgcagca tacacatgat tattcagaat actttacttc
    10681 tttttcagtg agtcgccctt gtgaagagac agaaacagag agagcctact ttaattattt
    10741 tttctattgt ttttttccaa atcaaatctc ttttcgacaa aaacaggaga ttggtttttt
    10801 attttccaca agcaaaaacc ttatttgtcg acaagtcggt caattgatga cttacttaac
    10861 tcaacagttt cctctcaacc atttagaaaa taaaatacca atttattttt attttcttgt
    10921 gttggcagtt gtttttttcg aactgttggg tgaatccagc agtagttttt ctacactttg
    10981 ctttccagaa gccacgtcca atcattctag ttcttttata caggaaaaga aattaagaga
    11041 aaaaatcgat acaatttttt caaaaaatgg ggaaagaaac caaatcagtc aataccttag
    11101 tcaattgatc caacacttac tacaaacaga aacgaaagag cagttactca tccatttgca
    11161 gataaccaaa cagtttacag gaaattatca tcttcaaagc catttgcagc agttatttcg
    11221 caaagatgct gttaaaatta ccgcatattc agaacatgct gatttgatca ttacagatca
    11281 gcatgagaaa atttcagatg aaacggagac tttctatctg gatacaacgc acaatacagt
    11341 gttatttggc aagttaataa aagcggttca tgaactgtat atgaaaaaag gttatgagaa
    11401 caaaacaaag aggatgtgac aaaattcttg tcacatcctc ttatt
//
LOCUS       DAZULR010000066        11328 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.068, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000066 DAZULR010000000
VERSION     DAZULR010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11328
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.068"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            250..675
                     /locus_tag="ACG8ZV_002380"
     CDS             250..675
                     /locus_tag="ACG8ZV_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFS4997654.1"
                     /translation="MHLHRISALAVQIGRYHHSETRAVMEGLEEAIQTTNDCPYRRTF
                     HSDQGWSYQMKAYRNKLKEYKIFQSMSRKGNCLDNSLMENFFGLLKQEIFHGKVYNCF
                     EELKSAIDSYIYYYNNERIKQKLNWQSPVQFRKTTVTVV"
     gene            complement(970..2103)
                     /locus_tag="ACG8ZV_002381"
     CDS             complement(970..2103)
                     /locus_tag="ACG8ZV_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFS4997655.1"
                     /translation="MLLNFKMTLTMLAFSLLVTGVILVSFFFLRNNLEGISIASTLGE
                     DVYFMEEGKTVQAETQMEASKSSNNQFMTISMIDKAYQDELFKYLPAMVLVICSAVML
                     LTFILWLVLRKIYSNQILAITRDLTFIDQVPKNTVKDEALNAAFNKLKDKFDGHLEDY
                     RRLNSYLTHEQKNAIAILRTNLEIERQHADQGNLMLLDRMTDSIDDILTLSNNSEDLS
                     TEVVDVSLICAEVCDAYKMNYPNLLFAFTEDQPTLIHGRDRWIYRAVSNLVDNAIKYG
                     EGKLVIVTISNQKGSVIIEVKDQGIGIPQEKQASIFSHQYRVHGLKQDGLPKTMDFRD
                     TDETFIQSVASKRNHIPRKSLNYRTPLEVFLSCIDKDILSSLI"
     gene            complement(2094..2762)
                     /locus_tag="ACG8ZV_002382"
     CDS             complement(2094..2762)
                     /locus_tag="ACG8ZV_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFS4997656.1"
                     /translation="MRVLVVEDNRELVLSVKKGLEQENISVDVAYDGESGEEKAFINS
                     YDGILLDLNLPKKDGLSVLQSLRAEEVESPVIIITARDEIEERAKGLDFGADDYLVKP
                     FELLELKARIRAVIRRYHGRALPQISIGALKIDPLGRRVSYQKTEVVLKPKEFDILLC
                     IAQRHPAVVSSEEISEHVYDEDFDPFSSVLRVHLARLKKKLAEAAEKEVLKTIRAKGY
                     QLCY"
     gene            complement(3218..4204)
                     /gene="lacD"
                     /locus_tag="ACG8ZV_002383"
     CDS             complement(3218..4204)
                     /gene="lacD"
                     /locus_tag="ACG8ZV_002383"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HFS4997657.1"
                     /translation="MNEEKRQYIKQLCNEDGVIGALAIDQRGALKKMITKFKGSEAEE
                     SEIVEFKEIVSSQLTKYASSILLDPEYGLPAADVRAKNAGLLLAYEKTGYDASTPGRL
                     PDLLSIWSVKRLKEAGADACKFLLYYDVDEAEEINNQKHAFIERIGSECQAENLPFFL
                     ELVSYDANISDATSKEYAIKKPHKVNDMMKEFSDPRYGVDVLKVEVPVNMNYVEGYGT
                     DEVVYTKAQAANFFKEQAEATNLPFIFLSAGVKAELFQETLRFAKNAGSTFNGVLCGR
                     ATWADGVESYIVDGKEAAMEWMNTQGRKNIEELNAVLKETATPVEVLTSSLS"
     gene            complement(4217..5143)
                     /gene="lacC"
                     /locus_tag="ACG8ZV_002384"
     CDS             complement(4217..5143)
                     /gene="lacC"
                     /locus_tag="ACG8ZV_002384"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009024 - tagatose-6-phosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HFS4997658.1"
                     /translation="MILTITMNPSIDISYPLETFKLDTVNRVRNVRKTAGGKGLNVTR
                     ILKQLDTEVIASGLIGGFLGEEIKKDLTQNEIAHDFLPISGETRNCIAVLHDGKQTEI
                     LENGPVITEQEARAFLQHFEKLAVKAEIISFSGSLPEGLPADFYRQMLQVCQPKPVVL
                     DCSGTALREVLRGSVKPKLIKPNTEELAGLLGREISTELSDLKAALSDSMFDEIEWIV
                     VSMGGDGAFAKHHETFYCVTIPKIDVVNPVGSGDATVAGLTAAIQQGLSDEAVLKQGN
                     VLGMLNAQEATTGYVQLANYQKLYDQILVEKV"
     gene            complement(5156..5671)
                     /gene="lacB"
                     /locus_tag="ACG8ZV_002385"
     CDS             complement(5156..5671)
                     /gene="lacB"
                     /locus_tag="ACG8ZV_002385"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_function: GO:0050044 - galactose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HFS4997659.1"
                     /translation="MKIAIGCDHIVTDTKMAVSDFLKSKGHEVLDMGTYDFTRTHYPI
                     YGKKVGEAVTSGEADLGVCLCGTGVGINNAVNKVPGIRSALVRDMTTAIYAKEQLNAN
                     VIGFGARITGEFLICDILEAFINADYQETEENKKLIAKIDHVEKASDKQSDPHFFDEF
                     IEKWDRGEYHD"
     gene            complement(5690..6118)
                     /gene="lacA"
                     /locus_tag="ACG8ZV_002386"
     CDS             complement(5690..6118)
                     /gene="lacA"
                     /locus_tag="ACG8ZV_002386"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HFS4997660.1"
                     /translation="MRVVIGSDSDGMELKELIKKKLIKEGITVVDKSETASEDFVEST
                     LAIANDLNENEGSLGIAVDGYGAGSFITATKVKGMVAAEVSDERSAYMTRKHNNSRMI
                     TLGSKIVGDELALNIVKEFLQANYDGGRHQVRVDMLNKMA"
     gene            complement(6138..6911)
                     /locus_tag="ACG8ZV_002387"
     CDS             complement(6138..6911)
                     /locus_tag="ACG8ZV_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFS4997661.1"
                     /translation="MLKTERQRSILAMCDRYGTITVKFIQEVLNVSDMTIRRDLEELA
                     QKKKLLRVHGGAQKIDYLEMSTSIEANELSHTEKKKLHTKEKEYIAKNAAAHINQEDD
                     TIFLGSGTTIELMTRYIKPSSLRIVTNSLPVFNLLSEIKRFELYLIGGLYREKTGAFV
                     GSIANEAVQKIGIKKAFVGVNGLKGSEVSNFSIEEGTLQKIVLDNAAEKCLVSDANKF
                     DHSDFYNFYDLRKIDKLFTDSTLSAELKSYYQQFTKIIQ"
     gene            7076..7555
                     /locus_tag="ACG8ZV_002388"
     CDS             7076..7555
                     /locus_tag="ACG8ZV_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFS4997662.1"
                     /translation="MNEFFFKDTVYVSDKQSQEEVFEEVYQDLLKKELVTEDFLENLL
                     ERERNYPTGLDLSPVSKILPDIAIPHTESEFVRTTRIIPIKVKNEIPFYNMISPSDQI
                     SASFLFMILNENGEAQAGMLANIMDFINSVDEEKLFSFFKLEDTEAIYHFLEEHFYI"
     gene            7612..7914
                     /locus_tag="ACG8ZV_002389"
     CDS             7612..7914
                     /locus_tag="ACG8ZV_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003063077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HFS4997663.1"
                     /translation="MIKILAACGAGVNSSHQIKSALETELKNRGYQVTCDAVMIKDIN
                     EEMLSHYDIFAQIANTDLGFDINIPVVDAGAILYRIPAMAEPVYQSMESAIQSLNK"
     gene            7936..9393
                     /locus_tag="ACG8ZV_002390"
     CDS             7936..9393
                     /locus_tag="ACG8ZV_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HFS4997664.1"
                     /translation="MNTIIDIANKVFTPLINLGAAPLMTIVLTVIALFFKVKPSRALE
                     GGLKLGIALTGIGAIIGILTTAFSDAMTAFVERTGISLNITDVGWAPLATITWGSPYT
                     LYFLLIMVIVNIVMLAMKKTNTLDVDIFDIWHLAIVGLFAIFCGANLFIASALVIFIG
                     VLKIWNSDLMKPTFNDLLNAPDSNPMTTTHMNYMMNPIIMVFDKIFDKIFPWLDKYDF
                     DAAKLNSKIGFWGSKFAIGIYLGIFVGLLAGQTPTQIFSLAFTAAVCLELFSLIGAWF
                     IAAVEPLSQGITDFANKRLKGRTINIGLDWPFIAGRAEIWAAANVLAPIMLLEAIILP
                     GNKLLPLGGIIAMGVTPALLVVTRGKLIRMIVIGAIELPLFLWSGTLIAPFVTQTAKA
                     VGAFPAGLNGSAMISHTTMEGPIEKFLGYLVGNASQGQIEFVIYAALALGAYLLIFIW
                     YARQMKKRNAAYAAEKEENASPATAHNMTYAAEAK"
     gene            complement(9986..10738)
                     /locus_tag="ACG8ZV_002391"
     CDS             complement(9986..10738)
                     /locus_tag="ACG8ZV_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFS4997665.1"
                     /translation="MLKTDRFQAIMSLLEVNGTVRVSDIMEKFSVSDMTVRRDLDEME
                     KQGLLERVHGGAKLKDFYRHVELSHREKQIMLQEEKQRIVEKANEMINDGDTIFLGPG
                     TTIELMSKIIQGDSLRIVTNCLPVFEELNKRKGNRKIYLLGGEMRETTQCFVGEITNK
                     SLQDMNFHKAFFSCNALNEQKIMTSTFEEGQTQQIALNNSVERFLLIDHSKIGKRDFS
                     VYYNLNDVTVVITDDDEQKHYEKIEKEEKYVV"
     gene            complement(10953..11180)
                     /locus_tag="ACG8ZV_002392"
     CDS             complement(10953..11180)
                     /locus_tag="ACG8ZV_002392"
                     /inference="COORDINATES: protein motif:HMM:NF019322.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTRA domain-containing protein"
                     /protein_id="HFS4997666.1"
                     /translation="MYQVFEEMGYPIKTVTRKLEVIKADDTISDLLDVEEGDPMFYFH
                     TQGFSLERLPVEYSISKYRGDINYFVFELAQ"
BASE COUNT         3258 a         2445 c         1932 g         3693 t
ORIGIN      
        1 tataaataac tcataaaaaa tattttgact ttcaaaatca cttttgctac cagaagttga
       61 ggcgaagtgt tttaagcata gttgtaccct agtttgaccg ttaaaaataa ataacgatcg
      121 ctagagtgca actatgtttg tttgccctac cgtcagcgtc ggcttggcct ctcacatcca
      181 ttaccgtcgg gattatctcc gttacatacc cttacaaaat acgccctgta agcattgcat
      241 gaaaccaccg tgcatttgca ccgtatttcc gccctagccg ttcaaatcgg tcgctaccac
      301 cattcagaaa cacgtgcggt aatggaaggt ttggaggaag ctatccagac cactaacgat
      361 tgtccctatc gtcgtacgtt tcactcagat caaggttggt cgtatcaaat gaaagcttat
      421 agaaacaaat tgaaggagta caaaatcttt caaagcatgt ctcggaaagg gaactgctta
      481 gataattcac ttatggagaa tttttttggc ttattaaaac aagagatttt tcacgggaaa
      541 gtttataact gtttcgagga attaaaatca gccatcgata gctatatcta ttactacaat
      601 aatgaacgga taaaacagaa attaaactgg caaagtcccg tccaatttcg taaaacaacc
      661 gttacggttg tgtaaaaata tcattttaga gcatgaaaaa aagagtggat ttctccactc
      721 caaaaaagtc taacttttgg gggtcactac atttttgatc ctttttattt gattaattat
      781 atccagctgg ataataattt tgggggcaac atttctatct tactattatc ttcctaaagt
      841 agtagacttt cttattggga aaaattacaa caaaaaggag tggcttagtt gacaactcct
      901 ttttgtttac aaatcaattg gatatctata aattgtattt tctaacgaat tttatagaca
      961 tctgatttgt caaattaagc tagacaatat gtctttatct atgcagctca aaaatacttc
     1021 caatggtgtt cgataattta atgattttct tggaatatgg tttcttttcg aggcaacgga
     1081 ttgaataaag gtttcatccg tgtccctaaa gtccattgtt ttaggtaagc catcctgctt
     1141 gagcccatgc actcggtact gatgagaaaa aattgatgcc tgtttctcct gaggaatgcc
     1201 aattccctga tcttttactt caataatcac gctacccttt tggtttgaaa tggtgacaat
     1261 taccagtttt ccttcaccat atttgattgc attgtcaact aaattcgaaa ccgcccgata
     1321 aatccaacga tctcgtccat gaatcagggt tggttgatct tcagtaaacg caaacaaaag
     1381 attcggataa ttcattttgt aggcatcaca aacttccgca cagatcagtg aaacgtctac
     1441 gacttccgtg ctaagatcct ctgagttatt ggataatgtc aaaatatcgt caatactgtc
     1501 ggtcatccga tctaaaagca ttaaatttcc ttgatcggca tgttgccgtt ctatttccag
     1561 attcgtacgc aaaatagcga tggcattttt ctgctcgtgg gtcagataac tatttaatcg
     1621 tcgataatcc tccaaatgac catcgaactt atcctttagc ttattaaaag ccgcatttaa
     1681 tgcctcgtcc ttcacagtat ttttaggaac ttgatcaata aacgttaaat cacgcgtaat
     1741 cgctaagatt tgattactgt aaattttgcg taaaaccaac caaagaataa acgttaataa
     1801 catgacggca gaacaaataa ccagcaccat cgctggtaaa tatttaaata gttcgtcctg
     1861 gtaagcttta tctatcatcg aaatagtcat aaattgattg ttggaagatt tcgaagcttc
     1921 catctgcgtc tctgcttgaa ccgtcttacc ctcttccata aaataaacat cttcacctaa
     1981 ggtagatgcg atactgattc cctccaaatt atttctcaga aagaagaaac tcactaaaat
     2041 cacgcctgtc accaacagtg aaaaagccag catcgttaac gtcattttaa aatttaatag
     2101 catagctggt acccctttgc tcgaatggtt tttaagacct ctttttcagc tgcttcagcc
     2161 agtttctttt ttagacgagc cagatgcact cgcagaaccg acgaaaaagg atcaaaatct
     2221 tcatcgtaga catgttcaga aatttcctca gacgaaacaa ccgctggatg acgctgagcg
     2281 atgcacagta agatatcaaa ttccttgggt ttcaggacca cctctgtctt ttgatagctg
     2341 acccttcgac ctaatggatc aatcttcaaa gcaccaattg aaatctgcgg cagcgcacgt
     2401 ccatgataac gacgaataac cgcgcgtatt cgtgctttta attctagtaa ctcaaagggt
     2461 ttgactaaat aatcatctgc tccaaaatcc aagccttttg ctcgttcttc aatctcatca
     2521 cgtgcagtaa taatgataac tggactttcg acttcttcag cacggagact ttgtaaaaca
     2581 gataatccat cttttttagg cagatttaaa tctagtagta tcccatcgta tgaattgatg
     2641 aaggccttct cttctcctga ctcgccatca taagctacat ctacagaaat attctcctgc
     2701 tctaggccct tttttacgga taaaaccagc tcacgattgt cctcaaccac cagtacacgc
     2761 atgtatattc actcctcata cggatttagt aattacactt atgcttttta gcatagtaca
     2821 cgctcttctt caaagtccac gttctttttg tgaagatttg aagaaattca tacattctgt
     2881 taaaaaacac ataattaaga atgattttac tgtttgaaaa tacctagaat agaaaaagac
     2941 tggaaccttt cctccagtct cactactttc tatttgcttg gttttcttgt atatactttt
     3001 caaagttcgt tggtttatga ccaataagcc tcgttagaat actgaaaatt gccatcaagt
     3061 cattaagtac cacatgtaag aaaatctctc taaagaaaaa ccccttcgtt ttaactcact
     3121 tactatttta gaattcgttc ccctaataat gcagcatgat tttacgcttt atgtataaaa
     3181 aaagactgca agcaattttg cttcacagtc tgatttctta tgatagtgag cttgttaaca
     3241 cttccaccgg tgtagcagtt tctttcaata cggcatttaa ttcttcaata tttttacgcc
     3301 cttgcgtatt catccactcc atcgctgctt cttttccatc aacgatatag ctttctacac
     3361 catctgccca agtcgcacgg ccgcaaagta caccattgaa ggttgagccg gcatttttcg
     3421 cgaagcgcag tgtttcttgg aacaactctg cttttacacc ggcgcttagg aaaataaatg
     3481 gcaggttagt ggcttcagcc tgttccttga agaagttagc cgcttgtgcc tttgtgtaca
     3541 cgacttcgtc tgtcccatag ccttccacat aattcatatt gacgggtact tccaccttta
     3601 acacatctac gccataacgt ggatcagaaa attccttcat catatcgttg actttatgag
     3661 gtttcttaat ggcgtattct ttcgaagtcg catcagagat gttcgcgtca taagaaacaa
     3721 gctccaagaa gaagggtaag ttttcagcct gacattctga gccgattcgt tcaataaagg
     3781 catgtttttg attattgatt tcttctgctt catcgacatc atagtaaagt aggaacttac
     3841 aagcatcggc gcctgcttct tttaaacgtt taactgacca gatcgataat aaatctggta
     3901 aacggccggg agttgacgca tcgtaaccag ttttttcata agctaacagc aagccggcat
     3961 tttttgctct aacgtcagct gctggcaagc catattcggg atctaataaa atcgatgagg
     4021 catatttcgt taattgtgaa gaaacaattt ctttaaattc aacgatttct gattcttctg
     4081 cttcgctgcc cttgaatttt gtgatcatct tcttcaaagc cccgcgttga tcaattgcta
     4141 aggccccaat cactccatct tcattgcata gttgcttgat atattgacgt ttttcttcgt
     4201 tcatttccgt atcctcctac actttctcca ctaagatttg atcatatagt ttttgataat
     4261 tggctaattg gacatagcca gtcgtcgctt cctgagcatt cagcattcct aaaacattac
     4321 cctgttttaa cacggcttca tccgaaagac cttgttgaat cgcagcggtc aatccggcaa
     4381 cggtcgcatc accagagcca actggattga cgacatcaat ctttggaatt gtcacgcaat
     4441 aaaaagtctc gtgatgtttg gcaaaggctc cgtcgccccc cattgaaacc actatccatt
     4501 caatttcatc aaacatcgaa tctgacaagg cggcttttaa atctgataat tctgttgaga
     4561 tttctcgtcc tagcagacca gccagctctt cggtattggg ttttattagc ttaggcttta
     4621 cactgcctcg caacacttcc cttaatgctg tacctgaaca atctaaaacg acaggctttg
     4681 gctgacaaac ttgcagcatt tgtcgataaa aatcagcagg caatccttct ggcaagcttc
     4741 ctgaaaaaga aatgatttcg gctttaacag ctaatttttc gaaatgttgc aagaacgccc
     4801 ttgcttcttg ttcagtaata acaggtccgt tttctaggat ttccgtctgt tttccgtcat
     4861 gtaaaacagc gatgcaatta cgtgtctctc cgctgatagg taaaaagtca tgagcaatct
     4921 cattttgagt caggtccttt ttaatctctt cacctaaaaa accgccgatt aaaccactag
     4981 caatcacctc cgtatctaat tgcttcaaga tacgtgtcac atttaggccc ttaccgccag
     5041 ctgttttgcg aacatttctt actcgattga ctgtgtcgag cttgaaggtt tctaatggat
     5101 aagaaatatc aatcgatgga ttcatcgtta ttgttaaaat catttgtcca cccgcttaat
     5161 cgtggtattc gccacgatcc catttctcga taaattcatc gaagaaatgc ggatcagact
     5221 gcttgtcact ggctttttcg acgtgatcga ttttggcgat caattttttg ttttcttcag
     5281 tttcttgata atcggcattg atgaaggcct ctaatatgtc acagatcaaa aattctcccg
     5341 taatccgagc gccaaagccg atcacattgg catttagttg ttccttcgca tagatagcag
     5401 tcgtcatatc gcgaaccagc gcactgcgga taccaggtac tttattgaca gcgttgttaa
     5461 tcccaacacc tgttccacac aaacaaactc ctagatctgc ttctccgcta gtcacagcct
     5521 ctccgacttt ttttccgtag atcggataat gggttctggt aaagtcatag gtccccatat
     5581 ccaacacttc atgtcctttt gattttaaga aatctgatac tgccattttt gtatctgtga
     5641 cgatgtggtc acagccaatt gcgattttca tttcattcat ccttcctaat tacgccattt
     5701 tatttaacat gtcgacacgt acttgatgac gaccaccatc ataatttgct tgtagaaatt
     5761 ccttaacaat attcaacgcc aactcatcgc caacaatttt tgatccaagt gtgatcatcc
     5821 gagaattatt atgtttacgg gtcatatacg cactgcgctc atccgaaact tctgctgcta
     5881 ccattccttt aacctttgtt gccgtgataa agctgccagc gccgtagcca tcaaccgcga
     5941 ttcctaaact accttcgttt tcattcagat catttgcgat cgccaaagtt gattccacaa
     6001 aatcttctga agccgtttca ctcttatcta ctactgtaat accttctttg atcaattttt
     6061 tcttgattaa ttcctttaat tccatgccgt cactgtctga accaattact acacgcattt
     6121 ttgtttcctc ctatttttta ctgaatgatt ttagtgaatt gctgataata actcttcagc
     6181 tcggctgaaa gagtagaatc cgtaaataat ttgtcgatct tgcgcaaatc atagaaatta
     6241 taaaaatcgc tatggtcgaa tttgtttgca tctgaaacca aacatttttc tgccgcatta
     6301 tctaaaacaa ttttttgcaa ggtaccttct tcaatactga aattcgaaac ctccgaaccc
     6361 ttcaatccat tcactccgac aaaagccttc ttaataccga ttttttgaac agcttcattg
     6421 gcaattgaac cgacaaaggc tccagtcttt tcccgatata gcccaccgat caaatacagt
     6481 tcaaatcttt ttatttcact taatagattg aaaaccggca gactattggt aacgattcgg
     6541 agagatgacg gcttgatgta tcgtgtcatt aattcgatcg ttgtacccga tccaagaaaa
     6601 atcgtgtcgt cttcttgatt gatatgagct gccgcatttt tagcgatgta ttccttctct
     6661 tttgtatgca gcttcttttt ttcagtatga gaaagctcat ttgcttctat agaagtcgac
     6721 atttccagat aatcgatttt ttgtgcaccg ccatgaacgc gtaaaagctt tttcttctgc
     6781 gcgagttcct ctagatctcg gcggatcgtc atatctgaaa cattcagtac ttcctgaata
     6841 aatttgactg ttatcgtccc atagcgatca cacatcgcta agatcgaacg ctgtcgttct
     6901 gttttcagca tattctgtac ctccacgacc ttataataaa acatttacga acatttttca
     6961 acacatattg ttcgtttatt ttcgtttatg cgttgacaat gattttgtaa gcggttatac
     7021 tcaacttgta aacatataaa taaacataaa cgaactaata aaggagctgt tttgtgtgaa
     7081 tgaattcttt ttcaaagaca ctgtctatgt ttctgacaag cagtcgcagg aagaagtgtt
     7141 cgaggaagtc tatcaagatc tgttaaagaa agaattggta accgaagatt ttttggagaa
     7201 ccttttagaa cgggagcgta attatccgac gggattagat ctctcacctg tctctaaaat
     7261 attgccagat atcgctatcc ctcataccga aagtgagttt gtgcgaacca cccgtatcat
     7321 tccaatcaaa gtaaaaaatg aaatcccttt ctacaacatg atctcgccaa gcgatcagat
     7381 ttccgcttca tttcttttca tgatcttgaa cgaaaatggt gaagcacagg ctggcatgtt
     7441 ggctaatatc atggatttca ttaattctgt tgacgaagaa aaactgtttt cgtttttcaa
     7501 attagaggac acagaagcga tttatcattt tttagaagaa catttttata tatagaagtc
     7561 tctgcctaac cgcaggataa aaaataaact tattttaagg ggagaattat tatgatcaaa
     7621 attttagcag catgtggagc aggcgttaat tcaagccatc aaatcaaaag cgctttggaa
     7681 actgaattga aaaatcgtgg ctatcaagtc acctgtgacg ccgttatgat caaagatatc
     7741 aatgaagaaa tgctgtctca ttatgacatt ttcgcacaaa ttgccaacac cgacttgggt
     7801 tttgacatta acatccctgt cgttgatgca ggtgctattc tttatcgtat tcctgctatg
     7861 gctgagcctg tttaccaaag tatggaaagc gcaatccaat cattaaacaa ataggactaa
     7921 agaaaggaaa agcatatgaa tacaattatt gatattgcca ataaagtatt taccccccta
     7981 attaatttag gtgcggcacc gttaatgacc atcgtattaa ctgttattgc tttatttttt
     8041 aaagtaaaac cgtcacgcgc tcttgaaggc gggctcaaat tagggatcgc cctgactggg
     8101 atcggagcta ttattggaat tttaactact gctttttcag acgctatgac agcttttgtt
     8161 gaacgcacag gtatttcatt aaacattaca gatgtcggtt gggccccact agcaaccatc
     8221 acatgggggt cgccatacac gctttatttt ttactaatta tggtgatcgt caatattgtc
     8281 atgttagcaa tgaaaaaaac caacacatta gatgtggata ttttcgatat ttggcattta
     8341 gcaattgttg gtttgttcgc gatcttctgc ggtgctaatc tgtttattgc ttctgcatta
     8401 gttattttca ttggtgtatt aaaaatttgg aactccgact taatgaaacc aaccttcaat
     8461 gacttgttaa atgcgccaga cagcaacccg atgaccacga ctcatatgaa ctacatgatg
     8521 aatccgatta ttatggtttt cgataaaatt ttcgacaaaa tcttcccttg gttggataaa
     8581 tatgatttcg atgctgccaa attgaatagt aaaattggct tctggggatc aaaattcgcg
     8641 attggaattt atttggggat ttttgttgga ttactagcag gacaaacacc aacgcaaatt
     8701 ttctcgctag cctttaccgc tgccgtctgt ttggaattgt tctctttgat aggcgcttgg
     8761 ttcatcgcag ccgtagaacc gttatcacaa gggattaccg attttgccaa taaacgacta
     8821 aaaggacgta ccatcaacat aggtttagac tggcctttca tagcaggccg cgctgaaatc
     8881 tgggctgccg ctaacgtatt agcaccaatc atgttgctag aagccatcat cttaccagga
     8941 aataaattat tgccactagg cggaatcatc gcaatgggtg ttaccccagc actattggtc
     9001 gtaactcgtg gaaaattaat ccgtatgatc gtaatcggcg cgatcgaatt accattattc
     9061 ttatggtccg gcaccttgat cgccccgttc gttactcaaa cagctaaagc agtcggagcc
     9121 tttccagccg gcttgaacgg gtccgccatg atctctcata caacgatgga aggcccgatt
     9181 gaaaaattcc taggttattt agtcggtaat gcttctcaag gacaaatcga atttgtgata
     9241 tacgctgcct tagcattagg tgcatacctt ttaatcttca tttggtacgc tcgtcaaatg
     9301 aaaaaacgca acgctgcata cgcagctgaa aaagaagaga atgcatctcc ggcaacggcg
     9361 cataatatga cttatgcagc cgaagctaaa taagctaaaa acaccccgaa tgtctttaga
     9421 cttcggggta ttattttacc tataaaaaat aaatagatgt aaaatccatt tcaaaaagca
     9481 tagcccatct cttgccacac ccaataaaga aattatcaac gtttatgctt tttttaactc
     9541 ctttaagctt gcctttgttg gtattcctca acgattcttt ttgtgttctt gtttgttttg
     9601 tgctttttga ctttttgttg tttaattgcg aattccttga tttctttttt cctgaatcgc
     9661 ttcgcatccc gcggttatgc gtgcgatttc atcattgctt tttctgatct aactcgtttc
     9721 atgtcaaaga gcttcagctg acttagtgtc catggttgtt ttgatatccc ttttcctcct
     9781 taataaagcg gtgattgata ctgctatttt ttccttcaca taaacataac atcccaaaaa
     9841 aatcgactat cttttttcaa atggtgtatt caagtattcg gaggaattag taatgatgca
     9901 ccctaaaaat aacataattc gcttaaattc aaggctacca aaaaactacc aagttctaat
     9961 tatctagagt ttggcagttt ctcatttaca caacatattt ttcttctttt tcgatttttt
    10021 catagtgctt ttgttcatca tcatccgtta taactactgt tacatcattc agattataat
    10081 atactgaaaa atctcttttc ccaattttcg aatgatcaat caataaaaag cgttcaacag
    10141 aattattcag agcgatctgt tgagtttggc cctcttcaaa agtcgaagtc ataattttct
    10201 gttcatttaa agcattacag ctgaaaaatg ctttatgaaa attcatatcc tgtagcgatt
    10261 tattcgtgat ttcaccaaca aagcattgag tcgtttcccg catctcgcca cctaatagat
    10321 agatttttcg attccctttt cgcttattta attcttcaaa aacaggcaaa cagtttgtaa
    10381 caatccgcag tgaatcccct tgaatgattt ttgacatgag ctcgattgta gttcctggtc
    10441 caagaaatat cgtatcacca tcattgatca tttcattcgc cttttccaca atccgctgct
    10501 tttcttcttg cagcataatc tgtttttctc tatgagaaag ctccacatgc cgataaaaat
    10561 ccttcaattt cgctccgcca tggacgcgtt ctaataatcc ttgtttctcc atttcgtcca
    10621 aatcacgtcg gactgtcata tccgaaaccg aaaacttctc cataatatcg ctgactcgta
    10681 ctgtaccgtt aacctctaat aacgacatga tcgcttggaa tcgatccgtt tttaacattt
    10741 catcgcctct tttcttttta agactatcaa attcttaaga aaagtgctag aacaagtttt
    10801 cttaagaagc cttctgcagg aaggaaagca aaatttttca gaatttgcaa gctgctattc
    10861 taaaaaataa aaccgaacga gcatgactgt catagtgaca gccttgttca ttcgactttt
    10921 atctttaata aatcatttta tttaatctga agttattgtg caagttcaaa aacaaagtag
    10981 ttaatgtctc ctcgatattt cgaaatcgaa tactcaacgg gcagacgttc tagcgaaaaa
    11041 ccctgtgtat ggaaatagaa cattggatct ccttcttcca catctaacaa atcgctgatc
    11101 gtatcatccg ctttgattac ttctagtttt ctggtgaccg ttttaattgg ataacccatt
    11161 tcttcaaaaa cttgatacat tttttctttt ctgatttgtc aaattaagct agacaatatg
    11221 tctttatcta tgcagctcaa aaatacttcc aatggtgttc gataatttaa tgattttctt
    11281 ggaatatggt ttcttttcga ggcaacggat tgaataaagg tttcatcc
//
LOCUS       DAZULR010000067        11148 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.069, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000067 DAZULR010000000
VERSION     DAZULR010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11148
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.069"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            6..305
                     /locus_tag="ACG8ZV_002393"
     CDS             6..305
                     /locus_tag="ACG8ZV_002393"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFS4997667.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="ACG8ZV_002394"
     CDS             378..1739
                     /locus_tag="ACG8ZV_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HFS4997668.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFLSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLLFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGILTMPIYLYGATYLAPILSDSAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="ACG8ZV_002395"
     CDS             1761..2021
                     /locus_tag="ACG8ZV_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997669.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="ACG8ZV_002396"
     CDS             2035..2787
                     /locus_tag="ACG8ZV_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HFS4997670.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="ACG8ZV_002397"
     CDS             complement(2881..3486)
                     /locus_tag="ACG8ZV_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFS4997671.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIEQAREWTDHLLTK"
     gene            complement(3542..4516)
                     /locus_tag="ACG8ZV_002398"
     CDS             complement(3542..4516)
                     /locus_tag="ACG8ZV_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HFS4997672.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DCPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4894..5613)
                     /locus_tag="ACG8ZV_002399"
     CDS             complement(4894..5613)
                     /locus_tag="ACG8ZV_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFS4997673.1"
                     /translation="MPKYEEIANILRERIRSKEYPPDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5740..7011)
                     /gene="celB"
                     /locus_tag="ACG8ZV_002400"
     CDS             complement(5740..7011)
                     /gene="celB"
                     /locus_tag="ACG8ZV_002400"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0019191 - cellobiose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HFS4997674.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7164..8561
                     /locus_tag="ACG8ZV_002401"
     CDS             7164..8561
                     /locus_tag="ACG8ZV_002401"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFS4997675.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWNHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSRLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKAIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGTIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8642..9082
                     /locus_tag="ACG8ZV_002402"
     CDS             8642..9082
                     /locus_tag="ACG8ZV_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFS4997676.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9229..9555
                     /locus_tag="ACG8ZV_002403"
     CDS             9229..9555
                     /locus_tag="ACG8ZV_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFS4997677.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9556..10305
                     /locus_tag="ACG8ZV_002404"
     CDS             9556..10305
                     /locus_tag="ACG8ZV_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease prefix domain 1-containing protein"
                     /protein_id="HFS4997678.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10331..10741)
                     /locus_tag="ACG8ZV_002405"
     CDS             complement(10331..10741)
                     /locus_tag="ACG8ZV_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFS4997679.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNK"
BASE COUNT         3536 a         1948 c         2291 g         3373 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttcgaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcctgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtctta ttgctgcttt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattacca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcctc acgatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgattcagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaaggaccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcaaaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgggagat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc tcgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccaatc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa aaatgaagta gcatgaagag
     3541 attattcacg ttttttattt gcatcacttg tatcgaaagg acggacatag gcttcaatgg
     3601 cttcacgacg ttcttctaag aatggaggaa gagatagttt ttctcctgct gattctgctg
     3661 gttcatcttc aaggaatcca ggacaatcag ttgctaattc aaacagtacg tgatgagcgg
     3721 ctaggaagta ctcagattgg aaatagaaac gatcgacgaa accagaattt ggcaattcaa
     3781 tcttattgat tacttgaatc cagtattcca atgcttcttt gtctgctaca cgcaatgcta
     3841 agtgatggat atttccaaat ccttcgattg cttttggcaa gtctgtccga tgttcaataa
     3901 tgatgcttgc accatttccg ccttcaccga tttcaaataa gtagaaatct cctgaatggt
     3961 ctgtttcttt gaatcctaag attttttcaa gaatcaagcg gatatgctct aattgactga
     4021 cacggacaaa gacaggtcca agtcctgtga tcgcaaactc tgtcggtaca ttgctgtttt
     4081 tccaaggaat gccagctgct acaccttgat tgttttcgtc agagatcaat tgataatact
     4141 gattatcgaa atcttcaaat tcgatatatt ttttgccgaa acgttcattg attgctgaat
     4201 gagtaacgtc atatttttca aaacgttcca accaaaagtc taatgctgcg tcacttggca
     4261 cacggaaaga agcacgagag atcgtatctg ttcctttttt tccttttggc tgatttggaa
     4321 aatcaaagaa agtcatatct gttcctggcg caccagtatc gtctgtaaag taaagatggt
     4381 aagtttcgat gtcatcttgg ttaactgttt ttttgattaa gcgcattcct aaaatatctg
     4441 taaaaaagcg gtagattttt gtagcgctag atgtcattgc tgtgacgtgg tgaattcctc
     4501 tgatttgtgt atccatgata aatttcctcc tgtcaactta caaaaagtaa gtagttgatt
     4561 tagacatagt atagagggtg catctctatt ttgcaattaa tttgtcttct aaagtatcag
     4621 gaaggaatca agaatggaaa agaggaggga cggatcaata aaataaaaag acttacgact
     4681 agctgtatcg atttcaaaaa aactagcttt aaaaagctaa ctttagaatc attacgggtg
     4741 gtcataagtc tttttatgct gagttatttt ttcatttttg agctaatgct taggatagga
     4801 tagaatgttg atttcacgat ctcttcttgt tacttgaaac tgcttactac tgtcacgatc
     4861 tcttggtaaa cggctttttc acaacctctt catttaagtt gaacgcacat ccagcacaga
     4921 atagttccga acatcaaatc ggtttcggct ggaagaatat tcaatcggct gtccatcttt
     4981 gagatagacg acttgctgaa cttccagtac aggatcgttt tctgcacagt tcaaatattg
     5041 ctgatcatat tcatcacttt tatctgcaga aatagcacga taagcccctg caaaatggac
     5101 attcaattct tgatgaagat gatcatagat agaggctaac aaatgttctt tttttaaacc
     5161 cggcacaaga tggactggca taaaagtatg ctctaaaaca tatggctcgc catctaagat
     5221 ccttaaccgg tgaatattgt agacaggttg ctcggcatcg atcatcaatc gttcttggat
     5281 atattgatta gggaattcaa catcaaaatg aatgatttga ctcttcaaag aacgatgtct
     5341 gcgtttcatt tggagactca aaccttcata ctcgttagcg ggcgatgtgt ctttttgcat
     5401 aaatggatga ttcaagattt tcgttcctga tcctcgctgc gaatagacaa gtccttccat
     5461 tgctaagata ttgatggctt ttttgattgt catccggctc gcaccaaatt ctttgaccaa
     5521 gtccacttga ttaggcaaaa aactatcggg aggatactct tttgaacgga tacgttctct
     5581 taaaatattt gcgatttctt cgtattttgg cacgttattc acctcttcta gagtataacg
     5641 aaagattatg cttccgacaa ctcgaagtag catctggaac attgtttatt cgaaaaaaga
     5701 ggtcgtgaca agtttttgtc acaacccctt aatgatctat taagcaatat ctaaatctgg
     5761 ttgtttatct agtactttca ggaatgggta ccagataaag gcaacgatga caaagtcgat
     5821 gacttgcagc ataccaccaa gccatgaatt tgttgctaag acaccgcttg caatgattgg
     5881 cacagtccat ggaacagaga cgccagttgg tgcagggaca agtccagcag ccattaccaa
     5941 ataattgaac gtcgttacga ttagaggtgc cacaacccaa ggaataagga ttgttgcatt
     6001 caatacgatc ggtagaccga agatcgctgg ttcatttaca ttgaaaatac caggtgctaa
     6061 agctaatcgt ccaacatcac gatactgttt ctttttaaga acaaaggcca tcaataaaac
     6121 gacagctaaa gtcattccag agccaccaat accaacagtg aaggtttcca tgaatggttt
     6181 tgtgatgatg tgtggtaatt cttttccatg ttgataagct tctaagttat caagcatcag
     6241 tgtattccaa atcgggtcca ttacagagtt gacgatgatt tgtccgtgaa gtccgaagaa
     6301 ccataagaat tggacaaaga acaaagcaat caatgttgca ggtaaactac ttcccaaacc
     6361 agttaatggt ttttggatca cttcataaac gacgtcatgt aagttagcat tgaaaatacc
     6421 agtcatcaca gcattgatta ctaagaaaat agttagtgtc actacagcag ggatcaaagc
     6481 ggcaaatgat tttgttactg caggcggaac tccatcaggc attttgatct gccagccgcg
     6541 tttcgtgatt ctgcagtaga tttctccagc caagaaagca gcgatcattc caatgaacat
     6601 tccttttgcg ccaagacgat caagtgaaag cacaccagtc acatcttcac cgccagcggt
     6661 tttcattgca aaaggcgtaa gaatcaagaa gctggcaaaa gacacggcac caccgaaaat
     6721 accttcaacg tcataagatt ttgataaata atagccgata ccaaaagtaa caaaaaccga
     6781 catgatgctc attgttgcat tttgcccatt accgaataag ttcgataaag ttccctttgt
     6841 tgcgtcactg aaaaaaggca agttattgat aacgacaacg atcgaaccga acatcgttaa
     6901 agggaaggaa agcatgaaag catcccgcag cactgtaagg taacgatttt gccctaataa
     6961 attagctaag ggcatgattt tctcagaaag cttgtccata aaaccgttca tttttattca
     7021 cctcaaattt atttgcaatc gattacatac aaagtataac gccaaaaatt ttaaatgtct
     7081 agtcattttc ataaaaagta ttgatttatt ttttagggtt cgttatgatt acgatatcaa
     7141 gaaaaaagag aggaagtaaa aaaatgaaaa cctacacatt cccagaaaat ttttggtggg
     7201 gttctgctgc tagcggaccg caaacagaag gaagagtaag tgatgatggt aaaggagaaa
     7261 atatttggaa tcattggtat gaattagagc ctgaaaaatt cttcgatcaa gtaggacctg
     7321 aaaaaacttc gcaagtttac acaaaataca aagaagatgt tcagttaatg aaagaaactg
     7381 gccataacac atttcgtaca tctatccaat ggagtcgttt gattccagaa gggacaggtg
     7441 aaatcaatca aaaagctgtt tctttttatc gagattattt tactgaattg ctggataatg
     7501 gtatcgaacc ttttgtgaac ctttaccatt tcgatatgcc actaccactg caagaaaaag
     7561 gcgggtggtt atcaagagaa acggtcgacg cttatgtttc ttatgcagca gcgtgctttg
     7621 aactgtttgg agatctggtc aaaaaatggt ttactcataa tgaaccaatc gtacctgtag
     7681 aaggaggcta cttgtatcaa ttccactatc caaatcatat caatatgaaa gaagcggtcc
     7741 aagtaggcta tcatgagaat ctagcaagcg caaaggcaat caaagcctac catgaaggcg
     7801 gacatgatgg tgagatcgga atcatcttga atctgacacc aagctatccg agagatgaaa
     7861 cgaacccaga agatgtaaaa gcggcgaaga tcgctgacgc attcttcaac cgatcattcc
     7921 ttgaccctgc agtgaaagga gagtttccac aagagttgat cgaaattgtc aaagaattgg
     7981 ctataatgcc agagatccat gaaggagacc tagaactcat ccgtgaaaac acgattgacc
     8041 tgctaggaat caattactat cagcctcgtc gaatcaaagc aaaagaaact ccaatcaatc
     8101 acgaacatag ccccatgcca gatgattatt ttgataatta cgacatgccc aataaaaaaa
     8161 tgaatccata tcgtggatgg gaaatttacg aaaaaggaat ctatgatatt ttaacgaata
     8221 caagagaaaa ctatggtaat atcaaatgct atatttctga aaatgggatg ggggtcgaag
     8281 gagaagaacg atttgttaac agcgaaggaa ctattgaaga tgattaccgg attgagtttg
     8341 ttacggatca tttgaaatac gtccatcaag caatccaaga aggaaccaat tgtgtgggtt
     8401 accacatgtg gacatgtatg gacaactggt cttggacaaa tgcttataag aatcgctatg
     8461 gctttatcgc tgttgatttg gcacaagacg gtaaacggac gatcaaaaaa tcaggtcgct
     8521 ggtttaaaac ggtctctgaa aaaaacggat ttgatgcctg atattttttg ataaaacgtt
     8581 cacaaaatgt ttgttctaac actgtaatcg tgctacacta acagtgaagg aggcgtttac
     8641 aatggtagat acttatcgta atattttagt agcaattgat ggttctgaaa aggcagaaaa
     8701 agcatttctt gaggcaatca cgattgccaa acgaaatcag gcaacgttgc acatcctgta
     8761 tgtcaatgaa gtaacaggca attactttgg tgattttgca tttgttacaa caagccttca
     8821 ggaagaattg gatgaggttg cggaaaacca gatgaaagaa catcgaaact tggcaattga
     8881 aaaaggcttg acagatatcg agacatatgt tctttacggt tatccaaaga cactgattgc
     8941 taatttccat gaatcgaaag aaccaatcga tctgattgtc atgggggcga caggtctgaa
     9001 tgcggtagaa cgtgcactag taggttccac tacttcctat gtagtcaacc acgcatcatg
     9061 taacgtcatg gttgtaaaat aaataaatta agggaacaga aagcaaaaaa gcataacgct
     9121 tcttttgctt tctgttcctt taattttttg taaaaaatta ctttacctga tgaagtaatc
     9181 atgctattct aattacaacg acagatggag taatatggag gaaagaaaat gatttcaagt
     9241 gatggaatac gcggatacaa tgatgcgatt attttatcga tccttaacaa aaacgattct
     9301 tatggatatg aaatttctaa aacgattcgt gagaggacaa atgattccta tgtgatcaaa
     9361 gagacaacac tttactccgt ttttgcccgt ttagaaaaga atcaactgat tgtttcgtat
     9421 cctggagaag tgactcatgg aaaaaagcgg acatattata aaatcactga aatagggcgt
     9481 aatcttttag aagaaaaaaa gcaagagtgg ctgacgacga aagacgtagt cgatcaattt
     9541 ttggagggaa attaaatgga tacaatccgt aattatttag acagtctttt tatcggagta
     9601 cctcaaagta ccgagataga taagctgaaa actgatttgt tggcaaatat ggaagaccat
     9661 tatcatgaat tgatgggaga aggaaaaaat gaacaggagg ccatcggtac agtaatttcg
     9721 acatttggtt caatcgatga attattagaa gaactagatg tcgaaaaaaa acatcaagct
     9781 gacgagacgg aaacaaacac agcttctatt tatttaagcg aagcagaaaa ctactggaaa
     9841 gaatacagag cggcaagtct ccaagtggca tcaggtgttc tattcattag cttatctttt
     9901 gcaagttttc ttttcttttg ttcagcaggg tatgtgttca tgggtatttc ttgtctgatt
     9961 ttcggtatag cattagctgt cggttttttt attgcttctg gtatgaaaat cacacgttta
    10021 aatcactttt tgcaccatcg gaaaatacct gaaaaagtat tagcagaagc aaaagaaaaa
    10081 gaagaagagt atcagcgaag ttttggcttc tcactgattg caggaattgg attatgtatt
    10141 ttttcacttt tcccactttt ggcttcttta atgtggtata tggatggtag tatcggtgcc
    10201 tctatatttt ttgttacggt aggaacggga gtcttcttga tcatttatgg cagtctggtc
    10261 cgtcattctt atcgtcaatt cactcaaagt gcttattact ggtgaatgta ttcagatttg
    10321 taaaaatatt ttatttattg cttacccatg taaaatcgtt atagacagat ttcagttgac
    10381 ttctgcgcca ttgtacaggg ataaaaagac gcatactatc ttcattgaat ccgactaata
    10441 atttctttcc gtcagtaatg atgggacgtt gtaacaaagt aaaatgcgag acgatcagat
    10501 cgacaagctc tgaggtcgta cattggtcga tttgatcttt caaattttta taatcaatcg
    10561 agcgtttagc taatagatcg tcaaatccgt tttctgttaa tgacaataaa taaaatatct
    10621 ctttccttgt taaaggctgt ttaggtgtga aaattcgttc tctgtaaggc atttgatggt
    10681 ctttcagcca gtttgccatc agatggtaac tatgtgtgcg agaagaatag atcgtaagca
    10741 taaaaaaact ccttaaatag tccattaatt tgttagatct gttgagataa ataataggta
    10801 aggagctgtg cataagcatt gatcaaaaca acccaaacat cattagaaat aactttctaa
    10861 agtcttaaac ttgcgacgag aaacaactag actaatagaa aaaatgtctt agccatttgg
    10921 cttcctgttt gtttttttgc ttatgctgca gctcctcggg aaagggttct aacaatttga
    10981 agaaggttga tgattgatct agtttaaatt gtgtgaaatt tgaaatctgg tgtttttact
    11041 agatgaatca cctaacaact atgattataa cttatagaac ttctgttttg tacttggttt
    11101 tgttatagtt gttataaagt tttattttat tacagaacat ttttaatt
//
LOCUS       DAZULR010000068        10548 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.071, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000068 DAZULR010000000
VERSION     DAZULR010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10548
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.071"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..488
                     /locus_tag="ACG8ZV_002406"
     CDS             <1..488
                     /locus_tag="ACG8ZV_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997680.1"
                     /translation="IEEVFVGDKCIFFDQPLLSDGYGIDETDIFAKVNSIFSGKKETL
                     IKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTLLISPISTISFSPSMMFEKTIN
                     SIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLSEEKILLPENWAELRKLVEYGI
                     I"
     gene            475..1896
                     /locus_tag="ACG8ZV_002407"
     CDS             475..1896
                     /locus_tag="ACG8ZV_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFS4997681.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLGIIAAGYTT
                     VFTYFLLFIFHYNIAKKITNKQLFDTKKICIIIIFVSIFSLILHILINQMLIRYVLTS
                     LLIISLVIYFLKIKNRIIDDYNS"
     gene            1909..2916
                     /locus_tag="ACG8ZV_002408"
     CDS             1909..2916
                     /locus_tag="ACG8ZV_002408"
                     /EC_number="4.2.1.115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050377 - UDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 4,6-dehydratase family
                     protein"
                     /protein_id="HFS4997682.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            2928..3932
                     /gene="neuB"
                     /locus_tag="ACG8ZV_002409"
     CDS             2928..3932
                     /gene="neuB"
                     /locus_tag="ACG8ZV_002409"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0016051 - carbohydrate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HFS4997683.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            3929..5077
                     /gene="neuC"
                     /locus_tag="ACG8ZV_002410"
     CDS             3929..5077
                     /gene="neuC"
                     /locus_tag="ACG8ZV_002410"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008761 - UDP-N-acetylglucosamine
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0006047 - UDP-N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase"
                     /protein_id="HFS4997684.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTI
                     LKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEIETALNKI
                     QDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
     gene            5050..5727
                     /locus_tag="ACG8ZV_002411"
     CDS             5050..5727
                     /locus_tag="ACG8ZV_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HFS4997685.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            5678..6859
                     /locus_tag="ACG8ZV_002412"
     CDS             5678..6859
                     /locus_tag="ACG8ZV_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HFS4997686.1"
                     /translation="MAIQLKLRKKELILNSRILLSSPHMGGTEEKYVAKAFKDNWIAP
                     LGENVDKFEESITKYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATV
                     NPILYQGAVPVFIDSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYER
                     ILAIANQFNVPVIEDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSD
                     KKYVEHSRFLATQARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIF
                     NRYKEAFSGIDRIEMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRA
                     LWKPLHLQPVFQGVKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIF
                     K"
     gene            6872..7849
                     /locus_tag="ACG8ZV_002413"
     CDS             6872..7849
                     /locus_tag="ACG8ZV_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFS4997687.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
     gene            7849..8757
                     /locus_tag="ACG8ZV_002414"
     CDS             7849..8757
                     /locus_tag="ACG8ZV_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HFS4997688.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEINSNDLATYILRYDDKIIE
                     IHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFF
                     ENVVTGKENWNDLYHANEVLKIAEEK"
     gene            8758..9510
                     /locus_tag="ACG8ZV_002415"
     CDS             8758..9510
                     /locus_tag="ACG8ZV_002415"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HFS4997689.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            9515..10462
                     /locus_tag="ACG8ZV_002416"
     CDS             9515..10462
                     /locus_tag="ACG8ZV_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HFS4997690.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT         3804 a         1336 c         1954 g         3454 t
ORIGIN      
        1 ggatagaaga agtttttgtc ggagataaat gtatcttttt tgatcaacct ttattatctg
       61 atggttatgg catagatgaa acagatattt tcgctaaagt aaatagtata ttttctggaa
      121 aaaaagaaac tttaattaag cttcatccta gagcaaggac aaatcgttat ggtgaaaaaa
      181 acatattgaa ttccagttta ccgtttgaag tcttgctact tgaaaatgac ttctcttcaa
      241 cacttttgat tagtcctata tctacaattt ctttttcacc atctatgatg tttgaaaaga
      301 cgatcaactc tattatgttg gctaaattaa ttttaaatga atatacagca ttatctgaag
      361 ataaaaaaga aacattgaca aatattgttc ttttctgtga acattataac cgtctatcag
      421 aagaaaaaat tttactccca gaaaactggg cagaattaag aaagttggta gagtatggga
      481 ttatttaaca cactttccaa gtcaaaatta gttaagtcca gtttctggta tactataggg
      541 aattttttta ttaagggaat ttcattcata actattccta tttttgtaaa tattactact
      601 caagcagaat atggtttgat taataatttc acttcatttg tatcaatttt ttcgattctt
      661 gttgggctaa gcctaaattc ggcaattaat aatgcaagtt ttgactataa agatgacata
      721 aatgaattta tgtcatcggt actttctcta gctacacttt cgttaattgt gttcttatta
      781 atagggaaca tatatttttt gttttcaaat gctttttttg atatgaacca acttgtattt
      841 aatttgatgt tattacaaag ttttgctagt tttgtaatta gttatatcca gtcttatttt
      901 acgattaact ttaaccattt taaatatttg attttatctt ttatatctac ttttttgaat
      961 attgcaatct ctgtagcttt gatgcagaca ttatattttg atgataaata tgttggcaga
     1021 gtagtcggcg gaacactgtc atttgtgttg ataggtttag taatttattt aagaataatg
     1081 ataaagggtg ctcatttttt tgataaaaaa cagtggagat acgctttaaa aatctctttg
     1141 ccgctaatcc cacattcctt agcaaatata gttttagcac aattcgatag aattatgatt
     1201 aattcttatt taggtcctgc tgcgggggga atatattcct acattagtaa cataggtatt
     1261 attctaagcg taatatggat gtctactaat aacgcctggg ttccatggtt ctatggtgag
     1321 atgagtaaaa ataatgaaaa aaaagtgaag aaagttagta actattattt agtagtcttt
     1381 actttgatta cgatgattgt aatggtagtt tcgattgatt tagcaaaatt tatggctccg
     1441 aaagactatt attctgggtt atctttagtg gttccgataa ccttaggcta tttctttcag
     1501 tttttatata gtttaccagt taatgctgaa ttttatgaga aaaaaacatc gtttattgcg
     1561 attggtacag tagcaagtgc tatagttaat atactattaa acatgatttt catacctagg
     1621 ttaggaataa ttgctgctgg atacacaacc gtatttacgt attttttact ttttattttt
     1681 cattataata tcgctaaaaa aattacgaat aaacaattat ttgacacaaa aaaaatatgt
     1741 atcataataa tttttgtatc aattttttct ttgatacttc atattttaat caatcaaatg
     1801 ttgattcgtt acgttttgac atcattattg ataattagtt tagttatata ttttttaaag
     1861 attaagaatc gaattataga tgactataat tcataggagg agatataagt gtttaaagga
     1921 aaaacaatat tagtaactgg cggaactggt tccattggaa gtgaaattgt tcgtcagctt
     1981 ttaaaatatg aaccaaaagc tatcagaatt tatagtagag gtgaagaaaa acaattttat
     2041 atgcaacaag agctctcaaa tcacactaat ttgagatttt taattggtga tatcagagac
     2101 tctcaaagga ttgattatgc atgtcgtgat gtggatatta tttttcatgc tgccgcaatg
     2161 aaacacgttc cagcaagtga atataatcct atggaagctg taaaaacaaa tgtgatggga
     2221 actcaaaatg taatagatgc agcgatcaaa aataatgtaa aacattttgt aggtatcagt
     2281 acagataaag tagtgagtcc tactaacacc atgggtgcga caaagttatt gagtgaaaaa
     2341 ttaataatag ctgccaatca gtataaagga aaaacagaaa caatattttc ttgtgtaagg
     2401 tttggaaatg tcatggggtc aagtggatct gttattcctc tttttagtaa acaaataaaa
     2461 aacaataaag atattacttt gacagatgtt gatatgacac gatttatgat gtcaataccg
     2521 gatgctgcaa gattagttct gtctgctgct atgaattcaa aatttggaga aacatatgtc
     2581 ttaaaaatgc cggcaatcaa tattttaact ttagctcaat cattaataaa aatatataat
     2641 gatacacatg atgaaaaata tagaggtgaa ataaaagttg taggtatcag gccaggagaa
     2701 aaattatatg aagagctaat gactacagac gaaattgaac gctcatatga aaatgataaa
     2761 atgtatatca ttccaccaca ctatcatgct actgacgaac tgtacaaaga ttatgaaaaa
     2821 attaaaatca ctgcatactc ttcagatgca acagaattaa tgagtggaca ggaatttatt
     2881 agaatcgcaa aagagaataa tgtcgtgact tggtaaggag ttttatgatg aaatcagaag
     2941 tatatgtaat tgcagaaatt ggtgtaaacc ataatggaag tctagattta gctttagaaa
     3001 gtattgataa agctaaagaa tgtggagcta acgcggttaa atttcaaaca tttaaaacga
     3061 ataagctagt ttccaaaaag gctccaatgg caaaatatca gaaggataat cttaaagagg
     3121 acagttctca atttgaaatg ctaaaaaaat tagaattatc tcaatctgat tttattagaa
     3181 taaaagatta ttgtatacaa aataaaattg attttttgtc tactcctttt gatgaagaaa
     3241 gtgcagactt tctaaaacaa attggtgtac aaggatttaa aattggctca ggagatttaa
     3301 caaatttacc ttttcttaga aaaatagata tgtatgggtt gccagtttta ttatctacag
     3361 gtatggctga tattcatgag gtcagtgagg ctgtagattg tttcatagat agtccagtta
     3421 ctattttaca ttgtacttca aattatccgg ctagttctga agatattaat ttattggcga
     3481 ttaacacatt aaaagaaatg ttcgggatac ccgttgggta ctccgatcat tcattgggat
     3541 atgatgttgg tatttgtgct gttgcgatgg gtgctaaggt aattgagaaa cattttacct
     3601 tggataagga actacctggt ccagatcata aagcttcttt agatcctcag gaatttgcag
     3661 attttgtaaa gcatattaga aacactgaaa tatttttagg tgatggtgtt aagcgagcaa
     3721 tgccttctga acttagtaca aaagaagtat caagaaaaag cctagtggtc actgagaatt
     3781 taaatgtggg agatattctt acagagaaat ctcttacaat aaaacgtcct ggaaatggaa
     3841 tagctcctaa gtttttatat caatatattg gcaaaaaagt taaaagacca ataagtgcag
     3901 atagtgttct gcttgaggaa gatgttgaat gaaaaaaata cttatagtaa gtggaacacg
     3961 agctgattat ggaatatata aacctgttgc tgagaattta ctacaagata attgggatgt
     4021 atcatttgtt gtttctggaa tgcatttatc ccataaatat ggatttacta aagaattgat
     4081 cttagctgac ggatttagaa ttagtggaga agttcaaagt ttgtttttag agaacaataa
     4141 gggaaacatg gctcggtctg tggcattaga gataaatggt ttcacaaata tatttgaaca
     4201 aactagccct gattttgtat tattactagg ggatagagga gaaatgttgg cagctgcgat
     4261 agcttgtttg tatcttggaa tcaaaacagc acatattcac ggaggcgaag tgtctggtac
     4321 tgtagatgaa tcaataagac atgccataac gaaaatagca tctgttcatt ttgctgctac
     4381 ggaaaaaagc aaagagcgtt taataaaaat gggggaagat tcttggagag tttttcccgt
     4441 cggagctcct agaatagata ctattttaaa taatagatta cctagtttta gagatataaa
     4501 agaaaaatat catctaaaat ttgaaaagaa aaaatacgtt ttgcaagtat ttcatccagt
     4561 tgtaaccgaa ctagaaaata tagaaaaaca aattttagct ttgatcaatt caatggaaca
     4621 acaatctcaa ccaattattt gcattttacc taatagtgat gctggtagcg aaattatcag
     4681 aaaaatgtac cagaaatatt taaaaacgga tattatttat attacgaatt tagagccgga
     4741 ggaatacctg actatattaa aagagtgcaa atttatgatc ggaaattctt cttctgggat
     4801 aattgaagct gcatcattca aaataccagt aataaattta ggaaccagac aaaatggacg
     4861 agaacaatct aaaaatatta taaatgcaaa tctaaatgaa aatgaaattg aaactgcttt
     4921 gaataaaata caagatcctc agtttataaa aagcttgaaa aatgttaaga acatctacgg
     4981 tgacggcaac agttctagaa gaataacaaa aacattgaat caaatattga atgatgggga
     5041 agatattaag tggattcaaa aacaaatagc ttattaaaat atactagtga tccatacatt
     5101 attattgggg ctggcggaca cgcaaaagtc attattgaaa ccttaagatt agaaaataag
     5161 ttaatatatg gattttttga tgataagcaa aataaaatgc aagatctgaa atatcttggg
     5221 aaaataaacg aattgaatag ctgggcggat agcaaaaaaa aaatctataa atttattgta
     5281 gctattggtg actgtgtagt aagaaaaaag attataaaaa aattgaatat gccaagtgag
     5341 caatatggaa tagctgttca tccaagtgct atagtggcaa aagaaatttc aattggttat
     5401 ggaactgtta tttttgcgaa tgctgtaatt aacccagatg ctgtaattgg agagcatgct
     5461 ataataaaca caggtagcat tgttgagcat gattgtagaa ttaataacta tgttcattta
     5521 tctccaggtg tatgcttagc gggtggagta catgtaggtg taggaactca aataggaatt
     5581 ggttctcaat gtatccagat gaagaaaatt ggatcttggt gtatgatagg cgcagggagc
     5641 actattgtta aggatattcc ctcacattcc ttagcttatg gcaatccagc taaaattaag
     5701 aaagaaggaa ttaattttga attctagaat tttattatca agtcctcata tgggaggaac
     5761 agaagaaaaa tatgttgcta aggcttttaa agataattgg atagcgccat taggtgaaaa
     5821 tgtggataaa tttgaagaaa gtattacaaa atatactggt tctaagggcg gagcttctgc
     5881 gttaagttca ggtacagctg ccatacatct tgccttaaga ctgcttaatg ttggaaaaaa
     5941 cgatattgtc tttgctcctt catttacttt tatagctaca gtaaatccta ttttatatca
     6001 aggggctgta ccagtgttca ttgactcaga acctaataca tggaatatga gccctgttgc
     6061 actagagagc gcattagaag aagctgaaag aaacaaccaa ttacctaagg caatcatcgt
     6121 agtgaattta tatggtcaaa tggctgatta tgaacgaatt ttagctattg caaaccaatt
     6181 taatgttcca gtgatagaag atgcagcgga atcgttaggt tctacttata agggaatttc
     6241 gtcaggctta tttgggacaa ttgggatcta ttcatttaac ggtaataaga tcatcacaac
     6301 ctcaggtgga ggagctctag tgtctagtga taaaaaatat gttgagcatt caagattttt
     6361 agcaacacaa gcaagagatc aagcaccgta ttatcaacat agcgaaatag gttataatta
     6421 ccgtctaagc aatatttctg ccggtatcgg acgtggacaa atggaagtat tgaatgatag
     6481 agtagctaaa cgaagagaaa ttttcaatcg atataaggaa gctttttctg gaattgatag
     6541 aattgaaatg atgccagaag tggatggcat ggtgccaaat cgttggttgt ctactttaac
     6601 gatcaatgat tataattcta ttgatcaagt agttaacgta ataaataaac taaatgaaaa
     6661 aaacattgaa acaagagctt tgtggaaacc actacatttg caaccagtat ttcaaggggt
     6721 aaaaatgtat taccatgata ataatcttag tgtgtcagaa aagttattta atagcggctt
     6781 atgcttacct tctggaagta atatgacaga tagtgaacaa gaatttgtta ttgatgagtt
     6841 taaaaaaata ttcaagtagg tgtgatattt tatgaacata ggaattattg gtttaggttc
     6901 catggggaaa agaagactta gactcattca agaacacttt aatgatattt tactatgtgg
     6961 tgttgatact aatgaggcga gacgaaagga agttgaaaag gaatttggaa taccaactta
     7021 taatagtcta acagaggcaa aaaatttgtt tgaaataaat tcagtttttg tttgtacatc
     7081 ccctataacc catgaattta ttataaaaga ggctttaaat ttagattgta atatctttac
     7141 ggaaatcaat ttattaaatg aatattatga tgaaataatc gaagtagcta aaaagaaaga
     7201 tagattactt tatctatctt ctacattttt gaagagaaaa gaaattcaat atattaagtc
     7261 taaagtgacg cataataaaa aaatttctta tcaataccat gtaggacagt atttacccga
     7321 ctggcatcct tgggaagatt atcgcaattt ttttgtttca aacaaaaaaa ctaatgggtg
     7381 tagagaaata ttcgctattg aattaccttg gattatagat acatttggga aagttaaatc
     7441 gtttactgta atgacccaga aattatccaa tcttgatatt gattattcgg acagtttcac
     7501 tcttattatt gagcatgaaa ctggtatagt tggaacttta agtgtagatg ttgtttcaag
     7561 agtagctaaa agaaatttaa ctataattgg tgaaaagatt ttaatagaat gggaaggtaa
     7621 cccggattct ctattttcat ggaatgaaga aacttctagt atgacagata ttcaattgta
     7681 cgatgaggtt atgcatgata ataattattc acatactatt attgaagatg catatttaga
     7741 ggagattaaa gaatttttca cgcttttgga aaagaaaatg gaaccccaat atacttttga
     7801 aaaagataag tatattatta acttaattaa cgacattgag gtaaattaat gatgaaagta
     7861 attttttttg ggttagggtc aattggaaag agacatctaa aaaatctaat aagctatgga
     7921 aaaaagaatt ctattaattt tgatataaca gcttatagta gcagtggaaa aaaagagttt
     7981 gaagaaataa cgtatattca aaatagagac gatttggata cacattatga tatagctttt
     8041 attacaaatc cgacttttaa gcatctggaa acactaaatg taattgttga aaaagttgat
     8101 tacatatttt tagaaaaacc tgctttttct gagagtattg atcttactca atataattat
     8161 gattacaaaa atatttatgt tgctgctcca ctgaggtata aaaatatcat ggaagttgtt
     8221 cgtaatagta ttcaaagtaa aaaagtatat tctgtaagag ctatttgttc tacttatctt
     8281 cctgattgga gaaaaggtac tgattataga aataattatt ctgcctttaa atctatgggg
     8341 ggaggagtag aattagactg tatacatgaa ttggattata ttataaacct atttggtttc
     8401 cctaaatcag taaaaaaaca gtttggtaaa tattcgaatc ttgaaattaa cagtaatgat
     8461 ttagcaacat atatattgag atacgatgat aaaattatag aaattcattt agattatttt
     8521 ggaagagttc ctacaagaaa atttcaattg tttactttag atgaatgtat caatgttgac
     8581 ttattaaata ataaaataag ttttgaagaa aacattgtta aagaaatgcc tgaatctgct
     8641 aatgatatgt atgagaagga gttgaaatat ttctttgaaa acgtagtaac aggcaaagaa
     8701 aactggaatg atttatatca tgcaaacgaa gtattgaaaa tagctgagga gaaataaatg
     8761 gaaattttat ttactatttg tggtagagct gggtctaagg ggtttaaaaa taaaaatttg
     8821 aaatatttgg caggaaagcc cctagtccat ttcgctttag caatgataga tatctatcaa
     8881 caaaaacatc ctgaacataa ttgcacgact tgtttgaata cggacagtaa tgagttagta
     8941 gaattgacga ctaagttaaa tccgtctgtg aaaattgtag aacgtaaacc tgaattagct
     9001 acagatactg tagggaaaat tgaagtgata cgtgattcat tcttacaact agaaagagaa
     9061 gataatatat ttgatttaat tatagattta gatttgactt cacctttacg tgaagtttct
     9121 aatcttgaag aattaataga tgaacatcta aaaaatttag ataaagacgt ctacttttca
     9181 gttgtttctg caagacgtaa tccctatttt aatatggtaa aaagaattga aaatgaagtt
     9241 actatagtta ataaatcaag atacacatct aggcaacaga cacctgaagt ttttgaaatg
     9301 aatgcctcaa tgtattcttt taaacctgaa tttctaaaaa aaagtaatta tatttttgat
     9361 gggcaatgtg ggataataaa aatgagagat tatctaattt tagatattga tagtgaagaa
     9421 gattttaaat ggttagaatt tttgtttcct aaatttttag aagattcttc ggagcttcaa
     9481 gatatctata attatttata tcggaggtaa aaggatgagc tgttatctta tcaccggtgg
     9541 ggctggcttc attggttcta ccttagccaa tcatttagga gaagaacatg tggtaatcgt
     9601 cgtcgatgac ttatcaatgg gaaaagtaga aaatcttgat atgacgaaaa atatcacttt
     9661 tattgaggga gatgtcgctg agaaatcctt gatggaagag atcatgaaag ctaataaatt
     9721 tgattatatc tttcatttag cagcagttgc tagtgtggca gattcagttg cccgaccagt
     9781 agaaacacat cgtgtgaatt ttgaaagtgt attaatgatt ttagaattga tccgcaagta
     9841 tcaacctgat ttaaaacgga tcgtgtttag ttcttcagcg gctgtttatg gggatgaacc
     9901 gactttacca aaaaaagaag agtccgtgat tcgcccattg acgccttatg cggttgataa
     9961 attcgctgca gaacaatatg tgctagatta ttgtcattta tatgatgtac ccggtagcgc
    10021 agttcgtttt ttcaatgtct atggtccaaa tcaaaatccg aattctccat acagtggtgt
    10081 gatttctatt ctcgtagatc gctataagaa acaaatcgta ggagaagcaa cttcatttac
    10141 attatttggt gatggaagcc agtctagaga ctttgtttat atagatgatg taatccaagc
    10201 attactttta gttgcgaatg aggaagctgc actggggaaa caattcaatg ttggaacggg
    10261 taaagcaacc acacttttgg aattgattca tgcaatcaat gaaattctcg gtgtagaatt
    10321 gacacttgaa tacaaagaag agcgttcggg tgatatccat gactctctag cagatattac
    10381 taagatccag tcaattggct atcaaccgaa atatggtatt ttaagtggaa tgactaatta
    10441 tttgaaaact gaaatcaatt aaaacatact aagataagat tagagggtaa attcaggctc
    10501 tttgtcaata aggactgatg agttttgtaa aatcaaatct gggataga
//
LOCUS       DAZULR010000069        10523 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.072, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000069 DAZULR010000000
VERSION     DAZULR010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10523
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.072"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(1..152)
                     /locus_tag="ACG8ZV_002417"
                     /pseudo
     CDS             complement(1..152)
                     /locus_tag="ACG8ZV_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
     regulatory      complement(300..466)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as
                     a genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
     gene            complement(691..897)
                     /locus_tag="ACG8ZV_002418"
     CDS             complement(691..897)
                     /locus_tag="ACG8ZV_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997691.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            complement(913..1527)
                     /locus_tag="ACG8ZV_002419"
     CDS             complement(913..1527)
                     /locus_tag="ACG8ZV_002419"
                     /EC_number="1.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HFS4997692.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            complement(1674..2357)
                     /locus_tag="ACG8ZV_002420"
     CDS             complement(1674..2357)
                     /locus_tag="ACG8ZV_002420"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HFS4997693.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            complement(2466..2924)
                     /locus_tag="ACG8ZV_002421"
     CDS             complement(2466..2924)
                     /locus_tag="ACG8ZV_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HFS4997694.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            complement(3008..4771)
                     /locus_tag="ACG8ZV_002422"
     CDS             complement(3008..4771)
                     /locus_tag="ACG8ZV_002422"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HFS4997695.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(4992..6452)
                     /locus_tag="ACG8ZV_002423"
     CDS             complement(4992..6452)
                     /locus_tag="ACG8ZV_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997696.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(6660..7586)
                     /gene="glsA"
                     /locus_tag="ACG8ZV_002424"
     CDS             complement(6660..7586)
                     /gene="glsA"
                     /locus_tag="ACG8ZV_002424"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HFS4997697.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(7609..9036)
                     /locus_tag="ACG8ZV_002425"
     CDS             complement(7609..9036)
                     /locus_tag="ACG8ZV_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFS4997698.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(9067..10281)
                     /locus_tag="ACG8ZV_002426"
     CDS             complement(9067..10281)
                     /locus_tag="ACG8ZV_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008519 - ammonium channel activity
                     [Evidence IEA];
                     GO_process: GO:0072488 - ammonium transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HFS4997699.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
BASE COUNT         3132 a         2172 c         1738 g         3481 t
ORIGIN      
        1 aataaatcaa ctcccccata agagtaagct gcatttatct tattcattcc gtaacctgga
       61 atatcgacat atgaatctct catgatagag atcagttttg cttgttgtgt tttctggttg
      121 tattgtgcaa ccagaagtga atccgagcga cctccaccaa tcgatctttt ttcaccgcat
      181 ctcctcctca cacagcaatc cacttgtcag gtgaggagcg agtttgtctc atcaaataag
      241 tcagtcacaa aaatataaag aaaaggtcag aaaccttttc gaacaagaat tctgacctag
      301 catcatctca tcgtccgagt tttagcacta tacaacgtaa agaaaacatt cttagctatt
      361 ggaaaaagcc ttaatccaac agtttctgtt ttacccattg gcgactttcg acgtttctgg
      421 gcaacagcct atgtttgtat aggagcctca cctaacaagg ttattactat attctattta
      481 cgagttcatg atagactttt cctaatgatt aggcaatgga atttgaaatg aaatagtgaa
      541 atttaacaat ctttaatatt ttttagaaaa aaataacaaa taagttgaaa gaatcccgtt
      601 gcaaattctt tcagttgcac caggattctt tgataatttt ttagttttat gtgttttttt
      661 atatgttttt tcacttttcg gaataaatat ttatttgtta aagtaattaa acaatccgct
      721 aatcgtttga tctggcattt ctatttcctt accatctaaa gtaacagtag taacgacaaa
      781 atggtcttgc aatggcggaa cttctaagta ctgcccttgc agaaaatcat tcactgtttc
      841 atattctttt ttcatttctt ttgaatctgt cgatggttta tagcttattt ttaacataac
      901 tagtgctcct ttttattcgg gacgtgcaat cgtgaaaatt tctcctattg ctgcataatc
      961 atttcctgcc aaacggctta cagcattcaa ttttcttgga tcgatccttc ctgtcttatc
     1021 atcatagact gtttcattta aatgatattt ctgtacttct agcaaaaata aatcagctgt
     1081 tactttattt ttattccgta tctcgacatg ttcatataag gatgtttcaa aacgaacttt
     1141 tgcttctgtc aatgctggta ctgaaatgat tactgaatca gttaaagtca agtcagtcag
     1201 gtacagttcg ctttcctcat taggcagatt ggctgctgtt ttatttactt cttctacgtt
     1261 gtcctcatca aggatatgga taacagcttc tcttgtctca agaatattct ttgctgtgtc
     1321 ttttactgca tcttgttttc tctggatcgc caaggataag atgggtcgat tcgaactgac
     1381 gatattgaag taactgaagg gtgcgatatt cactatatct tttgctgatt tagtcgttac
     1441 tactgctact ggtctaggga tgactgaacc aatcagcaac ttgtaatttt cacgttctgt
     1501 caattctgaa ggactccgtt caaacatggt ttcgccttct ttctataaaa ttcgttaaaa
     1561 agcagatctt gaagacaaaa tgaaaagtaa tgcttttttc atcttcttag aatctgcttt
     1621 aaactatcta tcaatttttc ttttttgtca agaatctgtg ccgtgcgtgt tttttagtta
     1681 tttgctttac ttgcggcttc gacatatctt ttagtgatca attgcggacg ggtgataata
     1741 gatccaacta cgactgaaaa agcacctaat tcatatgctt tctctacttg ttcaggagag
     1801 tcagtatgtc cttccataat tactgggata tcgacttgtt ctatgatttg attcaataaa
     1861 tcaaaatcag gtgtctgcgt ctttcgtgaa tattctgtat agcctgctaa agtcgtagac
     1921 aaaagatcaa aaccatcttc ttgcgcttga agcgcttcct caaaagtcga aatatctgcc
     1981 atagctaacc gaccgtgttc gtgaatcatt tggacaagtt cagcagttgt tttttctgtc
     2041 ggacgtttac gagaagttgc atccagtgca atgatttctg cttgcgtctc caaaagttct
     2101 tccacttctt tttctgtcgc agtaataaac acttctgacc catcgtaatc tcttttgata
     2161 atccctatta ccggtaaatc aacgattcgc ttgatttcat tgatatcttc tgtcgtattt
     2221 gctcgaatac caactgctcc gccttctttt gcagccaaag ccattctccc cataataaaa
     2281 gaactgtgta gcggctcgtt ttccaaagct tgacaagaaa cgacgactcc gcctttgatt
     2341 tgttccagtg tatccacaat atctcctcca gtaatgttat ataaaaatac agcttcatat
     2401 aaaaatgtaa cccttttcta ttcaggagac aataatgagc tatttctttc agcagacctt
     2461 tcttactaaa agaaaattac ttcaaattct tcgtatacga ccagcttctc ttctgtaaat
     2521 tctatgttca acgcttcttt ataagcatgt ttaaaaaact cagcatggac tttccgccaa
     2581 taagctaatg tccgatcccc ttctccttct ttccaagcat gctctttcgt gacttcacta
     2641 aaaggcaaga tggtcacatt tatatttttg atgatacaaa ctggttcatt ttttccattc
     2701 aggaccacgt ctaattgacc aacttttggt aaaggctcat tctcttgttt atacagatcg
     2761 taaccacttg atgtaccagt ctttatcttt tttacaacta gttcgctcaa ctcgtctgcc
     2821 attttttctg tatccccaaa tgaaaagaaa cctaattttt ctgattgata actaggatat
     2881 ttttcttgga actttttgac atattcttct acttgctgat acataacatc cacccctttg
     2941 ctttttataa tgaaaaaacc atccagatac tagtataaac aattatctgg atggtgagca
     3001 taatgaatta ttgaatattc aagacacgca gactatcttc aacgatttgt tttggtgtta
     3061 aatgataacg ttcataaagc tgccctacag gaacgctatc cgtgaattct ttctctgcac
     3121 caaaatttaa tacgttcatt gaagaatcac cataataacg actgatattt tcgccaaatc
     3181 ctcctgacaa actaccatct tctaatgtga tgactaattc gtgtgtttct tttaatttat
     3241 ctaatgtttc tacgtcattt tctgtgatcg ttcctggatt gatcaacgtt gcttcgattc
     3301 ctttttttct aaaagctttt actgtttctt ttcctaattc aagaaaaccg cctaaagcta
     3361 aaattgctac ttttcctcca ttatttactg tttgataggc tggaatacta taatcatttg
     3421 cgatagctgt accatgttct acaccatgtg taggaattcg gattgctaca ggctgcgctg
     3481 tttgttcgaa cgcccaatct agcatagaga tcatatcctc ttttgttgct ggagcaagat
     3541 atttgatgtt cgggatactt gataagtaag gaatgtcaaa tgttccttgg tgtgttcggt
     3601 cactagctga gatcgttccg ccaccgacta aaataatcac tggattctcg ttgatcgcta
     3661 aatcatgtga taattgatca tatgcccgtt gcaagaaagt acttgattgg aagacgactg
     3721 gacgtactcc ctgagaagcc aaagcagaag cgaaagtgat agagtgctgt tcagcgatcc
     3781 ccacgtcaaa ataatgatct ggatgttttt cttggaatgt tttcagtcca aaggcgcctg
     3841 gtatcgctgc attgactgcg gcaataggag ctgtacttgt ttgcattttc ttatccaaat
     3901 aatccatgat gatcatatta aatgtttctc cagaagttac ttgctttgcc tccccggtgg
     3961 acagatcaaa tggtacatgc caatgatatt tcattttatt atcgattgcc ggctgataac
     4021 cgcgaccttt ttccgtatgg acgtgaagta caatcggatg atcaatatct tttacttctt
     4081 caaataaacg gatcaccgtt tccagatcgt ttccattatc cacgtaacga taatcaaatc
     4141 ccattgcttt aaataggtta ttgctgcttt taccgttggt ttgacgaagc tcagctaagt
     4201 ttttatataa actgccatga ttctcatcaa tagacatctc attatcgttt actaatacga
     4261 ttagattgga ttgtaaaaca ccaccattgt tcaatccttc aaaagctaag ccaccactta
     4321 gggagccgtc accgataaat gctaccacat ttcctgattc tttcttcaga tctctcgctt
     4381 tagctaaacc tgttgctaag ctgatagatg tagatgtgtg ccccactgta aaatagtcat
     4441 gtttactttc atgttggttg gaatatccgc tcacttcacg gtaatgtcct ttttcaaaac
     4501 cattttttcg accagttaaa agcttatgac cataagactg atgggaaaca tcccaaacga
     4561 ttttatcctt tggtgaatca aatacataat gaaacgcaat cgttaattct actacaccta
     4621 gattcggacc aacgtgccca cctacatcgc tgtccttttg caagattttt tggcgcatct
     4681 cttctgccaa ctgtttcatt tcctcaacag ataatttttt gacatctgcg gggctattga
     4741 ttgcatccaa tacatgtaat actgtactca taatacattc tctcctccgt actatcttct
     4801 tttaatgaaa atagatttgt tacactttat ctattctact acttagagtt gactctaagt
     4861 caatagcatt ttaaaaaaat ttcagagaaa gcttgttata taagtagatc ttcgcacgaa
     4921 tcaggactca aataaaaacc ttctacagac aattaaaaag ctttgtagaa ggtctcctaa
     4981 ttaaggtctc atcaagaaat atgttttttt aataggtgaa gttcctgagc aatatgatac
     5041 aaatggatgt ttgcaccttt taatgagatt ggatagatct ttgtcttttc agtttctaat
     5101 ccattttgat agctagcagc atcgcacaaa accactcttt ttttcgcaca tagacattca
     5161 tcaggcaatt cttctaatga acgaaataaa ataggattta tttcagcgat gccttcttcc
     5221 gcatacaaat gaaattgggt tcgataaaaa aattgtttga ctgaactttc tgaaacaaca
     5281 aaaatttcta tttcctgtct ccccgcttgt tcactgttga tcaaagaaag acttttgacg
     5341 aattttcgaa tgaaattttc attccatctt agttggattt gatttttctt tttccactct
     5401 tccaatattt ctacaatttt tccgtacaga agttgttctt tttctgatag aagatagatc
     5461 ctttccggta aaaatacttg tccatctgcc cacaacgtac ggacaaattg taaaaaggat
     5521 tgcttgaaaa taaaattttc tgcatcgtcg atttcagcga tactaataat ctgtaaaatc
     5581 aattcattca gtgataggtc attgagaaca aaatttttat aaacaacttc gaaatctttt
     5641 cttaacagct ccatgttctc attggtataa tttctactgt tgaacaaaga aaaaatataa
     5701 tagacatctt cttcttgtaa gtctagaatt cctttttgct cttccaatcc ttgacagact
     5761 aattgaaata acggcttcgt ttctgcgctt ttcttatctt cttctttcag tccaagggga
     5821 aatgcctttc ttccgattgc gatctctatt cctcgtatga taaaggactt ttcatcttcc
     5881 gaatatcttc ttttaaaaaa atgagtctct acataatcaa tcaactcgtt acaagcttct
     5941 tctacatacg gatttttatt ttcatagcct tcccaattga cataacgtac taaagctagc
     6001 aagatgttcc gcgagtcaaa ttctgggata atgatttctt tatttttcaa ataatcattt
     6061 tctttaaaaa aatccaatac gatttttttg attgtatata ctttgctcaa agaaataaat
     6121 tcaagatcag ccagttctgt actcgtgaat ataccattaa aataataact taaaaacttt
     6181 aaaaaataag attgaccgta cagaaactgt gtgagctcag aaagagcaat accatgtttg
     6241 aatacgagtt tatacttatg cttctctctt acttgttctt ttatacaata ttctagacac
     6301 tcggctagac tttctagatc gtgaaggatc gttggtgtag tcacccttag agaaatagct
     6361 gtttgttcga tgtctatttc ttggaattca aataattgtt cacacagata cacttttcta
     6421 aatatatttc gctcgatgta attttccagc attcctgata cacgcctcca gtttttctta
     6481 tgattttatt taatcatatc tgtaaatcgt atttttgttt cctttttatt tagaaaagcc
     6541 ctttcaaaaa ccaataaaaa aagaaactgg gacaaaagtc aaacaagctc acaatttcag
     6601 cctcattgta ggtagctttg agccgtttgg acttttaccc cagcctcttt caagaatggt
     6661 tattcaaaga tgtcagcgtc tagttctttg actacatctt tcaacaattg gataccagct
     6721 gcgctgttac caaatggatc tagtgccggg ctgaagacac ctatgccgta acgatttggc
     6781 acagctgcca tcaacccgcc gcctacaccg ctttttgcag gtacaccaac atggacggaa
     6841 aactctcctg attcatcata caaaccagca gttgtcataa ttgatttgac gattgtagca
     6901 ctttcttcag taatgatttg tttgccattc caaggagcaa ttcctttatt tgccagcaca
     6961 gcagctaatt ttgctatgcc tgtagcggtg acattgaggg agcattgtct gaaataagca
     7021 tcgagtatct ccggtacgtc tccttcgatc atttgattac ctttcatata gtaagcaaga
     7081 gagcgattga tatcacctgt tcttgattca gaatgataga tttcttcatt caatgtgata
     7141 ttaggatcat cacagatctc tttcataaat gacaagattc gctcaaattt ttcatctgca
     7201 tctttaccgg caatcaacga ggttgttgca atcgctcctg cattaacaaa aggattcatt
     7261 ggatgtttgc gatgattgat ttccatattc atgatagaat tgaaggcaaa accggttggt
     7321 tccgtgttga ttgtttgaaa gactttttct attccgttgt ctttgattgc taataacaat
     7381 acgggaactt ttgacatgct ttcgatggca aagcgcacat cggcgtctcc tccctcaatc
     7441 agttgttttg tatccaaatc ataaatcgcc atacctaatt gtttgggatc cacttcagct
     7501 aatgctggaa tgtaatccgc cacttgtcct gtttgataat agtggaaatt ttttccaatc
     7561 aattgttcta attcttttac ttccatttga ataaccagct ttcatttttt atttttctgc
     7621 atgctggaat ttatgacggc atgcgtagat cgtaaatgga ataactaaga cgataagata
     7681 agaaacaatc agaatcgttt cataaatccc atgctgtcca gctgcgatac tagcaggtgg
     7741 aacaaatgag atacaaaaag caaaaagtga agtcaaaaga cctaaacaag caacgattac
     7801 ttttacaact tttccgcctg gaacctgata ggctctttca agactgtcat ctttaaaaac
     7861 cagcttcaaa tagcccgcga aaaacataaa gtacaacatc aggtagatta caacagtcaa
     7921 tgacatcgct gcaagaaatg aaagattatt ccccccgccg cttaatgtaa agacggctgc
     7981 ccagattgtt gcaacgatcc catttgcgat catcaaatga gcaggaacac cgtgtgtgtt
     8041 ttcttttgca aaatattcag gaagtaatcc ttcttctgct gctacgtgaa gtgcttttga
     8101 aggagaggtt acccaagaag caatttctcc gatgacacct aaacaaacaa gaatcgcaag
     8161 aattttcgca atccatgcaa gatttggatc aatgtgtctt aataggaatt ctaacgattg
     8221 aatcacccct gtattaagag acaaaccatg ttgaggtact gtagtagcga cggtcaatcc
     8281 gccaaaagta tctaaaatga ttgccagaat aaccaataca aacattgcta atggataatc
     8341 ctttttaggg ttttccattt catttgcatg actggcagat gtttctacgc ccatatatgc
     8401 taaaataaag gaaacaaaaa caaccagcgt aggcaatttc gaaaaatcag gaatcaatgt
     8461 tttcatagac agtatcgttt gtagtggagc gcctgaagcg acataatgga tccctaagcc
     8521 aaacaagact aatgctggca acaagatacc agctacaaaa ccgatccgag caatcaatga
     8581 agtgtatttg gttcctttta actgtgagag taaaatagcc cagaaaataa tcaataggat
     8641 tgccaatttc agatatttat tgttttgtat agcaccaata cccgttgcat aggataatgc
     8701 accagttaag aaatacagca tggtcaagta gccaactgtt atctcaaacc attggaaaaa
     8761 gattgcggca aaaccgaatc gttttcccaa tgtgcgactg acccaagtat agacaccgcc
     8821 tttttcccat cctttcaccg ttgccatctc tgctgcgcac aatgccacag ggataaacca
     8881 tagcaaaccg cctaataaca agaaaaatac taagctgaag cctgaggtcg cgaatgtggg
     8941 atattcatat aatgaaacga ccattgagat ggtcatagcc aaaaagccaa agaacgttaa
     9001 tttttttgca ggaattttcg ttttgctttg ttgcatgaat cttcctcttt tctatttgaa
     9061 tttgtttcaa ttgagtttgt tgccaaagaa gaaaaagtcc aatccttctt cttgttcttc
     9121 ttttgtagta gtgatcgttg taaagtgcat cgccgatttt aaaatcactg ttgtcagcac
     9181 ataggcatac acggcagtaa tgatgacacc aatcacttga atccctaaga agtaccagct
     9241 gcttggattc gttagtaaat ggctgttaga tgcaaagatc cctatcagaa tcgtacctgt
     9301 gaatccgccc atgccatgaa caccccacac atcaagtgca tcatcccatt gtttcttttt
     9361 acgaaaatca acagcagcat gacagacgat acccgcaatg atcccaatca gcatggcact
     9421 ttttgcttct acataaccgg cacaaggcgt aatggctgcc aatccagcaa cggatcctgt
     9481 tagtacgtcg acaaaatcaa agccatttcc ttttactttt gcaatgatca gccaagtaat
     9541 catcgcaaat gcaagagcga tgaatgttga accaaatgca ttgactgctt gttcatctgc
     9601 tcgaagtgca ccaccggaat taaaaccgaa ccagccaaac caaagcagtc ctgtaccgat
     9661 agcagctgcc ataagactgc tatgctgact tctttctcct aaaggaatct ttctttgacc
     9721 aagtgtgagg atacatgcta aagagccgaa tccagctgtc gtgtggatga ctgctccacc
     9781 agcgaaatct ctaaatccca tctgatccaa aaatccgcca ccccatatcc agtggcaaac
     9841 agggaaataa atcagcagat tccaaaaaat aacaagtata atatagcctt ttaaattcaa
     9901 tctccctgca aaagctcctg tcatcaaagg aacggtaatc acgataaaca tcagttggta
     9961 aagaaagaac attaaaaatg gaatcgttgc accatgaaac atgttgggga agcttgtaac
    10021 atgtctcatc aaaaagaaat ctgccgggtt tccaataaca ccgccgatat cccgtccaaa
    10081 ggccaatccg aatccaccaa atacccacat aatcgttgtt atcccaacgg agagaaaaga
    10141 ttgagacatg atcgttagta tattattctt ccgtgctaat ccgccgtaaa aaaaagctag
    10201 accaggagtc atcaggcaaa ccattgctgt acataaaatc atgaatgctg tatctcctgt
    10261 attgataggt aatgtattca tttttttcgc ctcctttcta cgattacgag tataaaagaa
    10321 ggtgtagttg tttttttctt ctgttttttt gaattaatac ttgcatttat aaaagacaga
    10381 caattaataa aagcttgatg tgttgtgctc tttttcgttt ttcacacaaa taaagacaaa
    10441 aaataaacgg tcttcttttt atagaaaacc gtttattttc gtcttttttt atttttaaag
    10501 atattttttc ataaggaata aag
//
LOCUS       DAZULR010000070        10350 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.073, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000070 DAZULR010000000
VERSION     DAZULR010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10350
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.073"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            174..323
                     /locus_tag="ACG8ZV_002427"
     CDS             174..323
                     /locus_tag="ACG8ZV_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HFS4997700.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            334..1848
                     /gene="dltA"
                     /locus_tag="ACG8ZV_002428"
     CDS             334..1848
                     /gene="dltA"
                     /locus_tag="ACG8ZV_002428"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HFS4997701.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            1845..3050
                     /gene="dltB"
                     /locus_tag="ACG8ZV_002429"
     CDS             1845..3050
                     /gene="dltB"
                     /locus_tag="ACG8ZV_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HFS4997702.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            3095..3328
                     /gene="dltC"
                     /locus_tag="ACG8ZV_002430"
     CDS             3095..3328
                     /gene="dltC"
                     /locus_tag="ACG8ZV_002430"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HFS4997703.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            3331..4599
                     /gene="dltD"
                     /locus_tag="ACG8ZV_002431"
     CDS             3331..4599
                     /gene="dltD"
                     /locus_tag="ACG8ZV_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HFS4997704.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            4740..5822
                     /locus_tag="ACG8ZV_002432"
     CDS             4740..5822
                     /locus_tag="ACG8ZV_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HFS4997705.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            5822..6625
                     /locus_tag="ACG8ZV_002433"
     CDS             5822..6625
                     /locus_tag="ACG8ZV_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HFS4997706.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            6695..7435
                     /locus_tag="ACG8ZV_002434"
     CDS             6695..7435
                     /locus_tag="ACG8ZV_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFS4997707.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            7446..8450
                     /locus_tag="ACG8ZV_002435"
     CDS             7446..8450
                     /locus_tag="ACG8ZV_002435"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017118 - lipoyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HFS4997708.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(8495..10339)
                     /locus_tag="ACG8ZV_002436"
     CDS             complement(8495..10339)
                     /locus_tag="ACG8ZV_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997709.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
BASE COUNT         3334 a         1706 c         2090 g         3220 t
ORIGIN      
        1 tttttaaaag tacgagaaat tataaagaaa aaagcagtga tttgatgtgc tatttttata
       61 aaagctatgt gacaaaactg ttagtaaaaa aacggtttct gtaagctaga cacatgtttc
      121 tttttgtcaa aattagttac actttgtgtg aggttatatg aggagggaat ccaatgaaca
      181 aatggcgttc taatccaaaa ttgaattatt ggggaaaatt catcattcga acaatttttt
      241 atagtgcagt actgctgttc ctgatttatc tgtatcacta taaaaatatt caaggaggaa
      301 cttttatcta taacgaattt taggaggaag agtatggaaa tcaaaacgat tattgaagca
      361 atcgatgatt ggggaataaa tgaacctgat cgagttgctt atcaggcgga tgagacgcat
      421 acttttggtg aattgaaaca agcatcagac gcacttgctt attatttaga aaaaaaggta
      481 gaaggcgatg gaccaattgt cgtttttggc aatttggagt ttgaaatgat tgtctcattt
      541 ctaggggttg tcaaatctgg ccatgcctat ttgccgattg aagagcatac acccaaggag
      601 cgtatcctat cgatctttcg ggtggctaaa ccatctatgg tcatcagtat cggggactgg
      661 atagaagata ttccttcggt tcctgtcata acaaaaaaag aatttcaaga aatcaagaag
      721 ataccagtag gattttatcc cagaaatagc gtaaaaggta cagaaaattt ttatattatt
      781 tttacttctg gtactactgg agaaccaaaa ggcgtacaaa tcagtcatga taatctagtc
      841 agctttgttc aatggacgat ggaagacttt gggatcaagc ctggtatgca tttcttagcc
      901 caagcgccat tttcttttga tttatcggta ttttctattt atcctgcatt agtttctggc
      961 ggaatgctga agccgttaaa taaagcagtt gttcaagact ttcgtcaatt attcgcgaca
     1021 ttgccagcct tgaagttgaa tgtgtgggtt tctactccat catttatgga tatttgcttg
     1081 atggaaccta cattcaatgg agaaaatgtg ccggaattgg acatgttttt attttgcgga
     1141 gaagaattga cgaaaaaaac tgcagaaagt ctacttgatc gattcccaaa tgcacggata
     1201 tataatactt acggtccaac agaagcaact gtagctattt caagtattca gattgaccag
     1261 catgtactag atagttatga ccgactaccg attggctacg taaaaaaaga cacgaaagtt
     1321 tctattgtcc aagaaggtaa acctgtttca aaaggagaaa cgggtgaaat cattattgca
     1381 ggaccaagcg tatcaaaagg ttacctgaac aatcccgaaa agacagctgc tgcgttcttt
     1441 tgtcaaaatg acttagcaag ttaccataca ggggatgcag gtagactaga tgaatatggg
     1501 cttttatttt atgaaggacg tatggatcag caggtcaaat tacatggata ccggattgaa
     1561 ctcggggata tcgaacatta tctgctccaa gacaaccgaa tcaaacaagc tgtcgtcgta
     1621 ccaaaatacc aaggaacaaa agtacagcag ctggttgctt ttgtcgtatt agaaaacaaa
     1681 acgaaacagc cggattttca gttgactaaa tctatcaaag aacaattact agaagttgta
     1741 atggattata tgattcctca gaagttccat tatgtcgatc tgctgcctca gacagttaat
     1801 ggaaaaatcg atcgaaaaaa attaacagct gaggtgaatc ctgaatgatg ttacctcata
     1861 tgatccctta tgcagagccg ttttattttt ttcttttagc cattgcgctt gtaccgatcg
     1921 ttctatcttt attgatatgg gaaaaaagat taccagttta tcaatcagca gtgacacttt
     1981 tctttttatt tgtcagcttt ggaggtaatt attggcaaca gggagcggcg ctgattgggt
     2041 atgttttgtg gcagacgata cttgtatggg gctattttgt ttatcggcaa aggaaaaatc
     2101 agacaggatg gttttttgcc gccgttattt tagcgataat tccactgttt ttaacgaaag
     2161 tgactccttt ttttgaacat ggaaaagcat cgttacttgg ttttttagga atctcttatt
     2221 taacctttaa atctgtacaa atgatcatgg aaataagaga tggcatgatc aaaacatata
     2281 agccatttcg ttatatccag tttctgctgt tctttccaac aatctcttct ggaccaatcg
     2341 atcgctatag gagatttgaa aaagatcagc tccatccgcc tgttcgtgat aaatatgttg
     2401 atcttttggg aaaaggcgtc caaaatattt ttgtcggttt tttatataaa ttcattatcg
     2461 gttattattt tggtcaagta ctgcttcctg tagtgggacg cattgcctta cagcatggtg
     2521 gtatttcatg ggcattagta ggttatatgt acgtgtacag tatgtatttg ttttttgatt
     2581 ttgctggcta tagcttattt gcagtcggta caagctacat gatgggatat cagacaccaa
     2641 tcaatttcaa taaacctttt ttatcatgga atatcaaaga attctggaat cgttggcata
     2701 tgacgctgtc cttttggttc cgtgattatg tatatatgcg attgatgttc ttcatgatga
     2761 agaaaaaatt ttttaaaagc aagatcgtaa tgtcaaatat cggttatttt gctttgtttc
     2821 ttctaatggg tatatggcat ggattgacgt ggtactacat cgtatatgga ctgtatcatg
     2881 cttgtctgat ctgtctgaca gatgcatgga tccgatttaa gaagaagcat aaagagcagt
     2941 tgccttctaa caaatttacg catggcttag ccgtattttt gacatttcaa gcagtatgtt
     3001 ttagcttcct gattttttca ggatttttag ataaactttt ttttagctaa cgaatagtga
     3061 catattaatt tatataacaa aggagaaaag gaaaatggaa gaacaaattt tatcaatctt
     3121 agaagaaata acaggaacag atgaagtaag aaaaaatcgt gatattgatc tatttgatga
     3181 agggttgctt gattctttag catctgttca attattagtc gagctagacg gagagctgga
     3241 tatccaagtc cctgtatctg aattcgagcg agaggattgg agcacaccga ataaaatcat
     3301 tcaacaagca actgcattga agggttgagt atgaaaaaga aactttttgc tattttcggc
     3361 ccggttgttt tagctgttgg cttactgttt gtgtttttta cctcctccta tcaagtagat
     3421 atctctaatc cagaaacgat tagacgtgcc tcttcttcca tgtcagtgaa cgtgttgaaa
     3481 ggagatgcga taaaaaatta tgcattatct gaaaaacaat atattccttt ttttggctca
     3541 agtgaattaa gcagaatcag tccatttcat ccgtctgttc tggcagaaaa ataccagcga
     3601 aactatcgtc catttttgct gggagcaccc gggacacaat cgttaagcca atatatgatg
     3661 atgcgttctg caggagatgc tatgaaaaac aagaaagtcg tctttattat ttctcctcag
     3721 tggttcgtta aaaatggtgt aaaaactgat tactttaata cgtattattc tgaacttcaa
     3781 acatacgact ggttgttttc aatgaagaaa gtaacgcctg ctgatcgcta tttagctaga
     3841 agattattaa ctttctcaaa agtaaaagag aatgatacgt tgacggcgat tctgcaaacg
     3901 atcaaaaaag ggaagctacc tttacctgaa tctttgaatc agctgcgcag ccaatggaac
     3961 atgctgaaga gagaggatga agtattcagc aatattgggt tgaaagatcg acagcaaaaa
     4021 atcgatcatg agtcaaaacg attaccaaaa caataccaag aaacagaatt atccatttta
     4081 gcaaatcaaa ttggagaacg agaaacgacg aataatccat tcgggttgaa aaacgatttt
     4141 tatacgcatc gtatccgagc ccacgagcca gagctcaaac agtcacaaaa aaattgggat
     4201 tatcgttttt cgccagaatt ttctgatttt cagctggtct tggatcaatt agcaaaaaac
     4261 cataacgaag tattgttcat catcccaccg gttaacgaga aatggagcga ttataccgga
     4321 ctatctcaag aaatgttaca aggatttgcc aaaaagatca aatttcaatt aaatagccaa
     4381 ggattcaatc gaatagctga ttttgtcaat caagcgggta ccaactattt tatggaagac
     4441 acgatccatc taggctggaa aggctggttg gctgcagatc aacagatcag accgttttta
     4501 gaagaaaatc atattactgc tagtaagtat catcttgacg atgctttttt tagcaaatct
     4561 tggcaacatc aaataccaga taaactacaa ttaaaataaa gaaaacaggc gagtgttgct
     4621 cgcttgtttt ctttattttt gaatattctg aataaaagat aaaaatacca agtttgcctg
     4681 aacaaaaatc ataagcaatg gtataatcac aatatgaata tagaaatggg ggaaaacatt
     4741 tggatacaaa agaagaacag ctacttattg atttaacttc tgcaaaagga gtacctggaa
     4801 atgaagaaga ggtaagagaa gtattcagag aatatgccaa accattcgct gatgatattt
     4861 tttatgacgg tttaggcagt gtgattgcca aacatggtgc tggcggaggc cccaaggtct
     4921 ttatttctgg acatatggac gaagttggtt ttatggtaac aaaaataacc gaaaaaggat
     4981 tcttggaatt ccaaactctt ggaggttggt gggggcaagt catgcttgct cagcaagttg
     5041 aaatcaaaac acgtgaaggg aaaatcgtcc acggtgtgat tggttccaaa ccaccacatg
     5101 ttttaacacc tcaagtaaga aataaacctt atgaaataaa ggatatgttc attgatattg
     5161 gcgcatcaag ccaagaagaa gccaaagagt ggggcatacg tcctggagat atggtcactc
     5221 catatattga atacaaacga atgaatggca gtaaatattt actggcaaaa gcatgggata
     5281 atcgtatcgg gacagctgtt tctctgcgag tattagagaa tctatctaaa gaagcacacc
     5341 caaatgtttt attcgcagga agcgatgtgc aagaagaagt aggcttgcga ggtgctcgaa
     5401 caagtacaca ccttgtaaat cccgatattg cttttgcttt agatactggt acagcaggag
     5461 acactccagg aatgacacca aaagaagcag attcgatttt aggaaaaggc ccacagattt
     5521 tgatttttga tgcatctatg atcccgcata aaaaattatt gaattttgtt attgatgtag
     5581 cagaggaaat ggatattcca ttccaatata cagtgatttc tggcggagga actgatgcag
     5641 gacaaatgca tttgacaaga gatggtgttc cgtctgtagc cattaccgtt cctgttcgtt
     5701 atctgcattc ccatacatca gtgattcatg aagatgatta tttgaataca gtgaaactag
     5761 tcacagaatt agtgaaacgg cttgatagtg aaacagttga aaaaattcgg agttatgaat
     5821 aatgaataat agaataccta tttctgaata tcggaaaaaa gcacgagttt ctttggaaaa
     5881 tcaatgggga atcaatactt ggcttgtttt cttatctata atatttacga gcgtcatcca
     5941 gaactttttt gacggtttca gtccttttcc ggaagaaagc atgcagcagc acttattgag
     6001 ttttctagtc gataatttac ttttattcgc attcaactat gcattgtttt acattgcgct
     6061 agtagttgta cggggtggca gaccaaaaag taacctttta ttttcagttt tccaaagaaa
     6121 gtattttggt tcgatacttg gcatcaattt gatcaattca gtcatcaact ggctactcaa
     6181 cagtttaatc tttctgccca tgtttttaat cagcggagtg agtacttata tgcagctgct
     6241 tttcagttca aatgcggtac ctacgggtgt catgccagaa gattttcttg atatcagctt
     6301 tgttttatcg atgataggga tgatttttgt ttcagcactc atcatgagta ttgttggcgg
     6361 tttattccaa tttgctgcat ggacaaagtt cgactatcct gatttgtcgg ttattcaatg
     6421 tttgaaatat ggctggtttt tattgaaaga tagaattggt acgtatattt tgttgcagct
     6481 gtcttttatc ggctggtatt tgctaggagc aatcgctttg ttcatcggtc ttttgtgggt
     6541 cattgtttat gtgaatgtgt cagttgcaga attttatgaa caagcacgga ttgaaaaagg
     6601 aggtccagac gcctatttta cttagcatgt aagcagttta ttcatcaaaa aaataacttt
     6661 tgtggtagga taaatctttg agggggaatg tacgatgaaa ttaactgttt taggatgctt
     6721 aggagcgtat ccttataaaa atcaagggac aacaggttat ttgcttcaat ctgacgggtt
     6781 caatttgttg atcgatgcag gtagtgctac gctgatcaaa ttacaagaac accttgatcc
     6841 acttgatcta gatgctgtga tccttagcca ttatcatcat gatcatattg ctgaccttgg
     6901 tgtattacag tattactggc aacttcatcc taagagaaat ccggagacat tgctttcaat
     6961 ttatggacac acaaaagatt ccattcactt tgaagaattg acgttggaaa atgtctcaaa
     7021 aggacatcct tattttgaag ctgaagaatt aaaaattggt ccttttctga ttacttttat
     7081 ggaaacaatc catccagtag tatgttacgc catgcgtatc gtagaagaaa caacggggaa
     7141 agtattcgta tttacaggtg attcaggtta tttggaaagt ttcgctgatt ttgcgaaaga
     7201 tgctgatttg tttctagcag atacctatct ttttgaagga aatgaacatc atcatgccca
     7261 tttcacttca aaagaagctg gagaacttgc gaaatcagct aacgtaaaga aacttgtact
     7321 tacacaccta cctcagtttg gtgatttaga acaattgaaa aatgaagcgc aaaaggcagc
     7381 aggcaaaggg attgatatag aacttgctgc agttgacaaa gtgtttaaca tttaggagga
     7441 agaacatgat ttttgtacca aatgaaaacc acgacccaag aatcaattta gcaattgaac
     7501 aatatttgct gcaagaaatg cctttagatg aacctatttt gctcttttat atcaatgaac
     7561 cttcaatcat catcggcaga aaccaaaata cgcttgaaga aatcaatcga gattatgtgg
     7621 aagaaaatgg cattcatgtt gtccgtcgct taagtggagg cggagctgtc taccatgatt
     7681 ttggaaacct gaactttagt tttatcatgc ctgatgatgg ggattcattc cgtgactttg
     7741 cgaaagtaac acagccaatc atccaagcac ttcatgaatt gggtgttgct ggggcggaat
     7801 tgaaaggccg aaatgatcta gtcattgatg gcatgaaatt ttctggcaac gcgatgtatg
     7861 ctaccaacgg tcggatgttt gctcatggaa caattatgtt cgactctgat atcaatgaag
     7921 tagtcaatgc attaaaagta aaaaaagaca aaatcgaatc aaaaggaatc aaatcgatcc
     7981 gttctcgtgt aacgaatatc aaaccatttc ttccagaaga aaagcaaaaa atgacaacag
     8041 aagaatttcg tcaagaaatc ttgttgaaaa ttttcggcgt agagtcagta gaagaagtaa
     8101 aaacgtacga attgactgat gaagattgga aaaaaatcaa tcgaatctct gaggaatatt
     8161 atcgaaattg ggattggaat tacgggaagt ctccagattt caatttctct cgccaaaaac
     8221 gtttttctat cggttcgatt gaagtccatt tgaatgtctc agaaggaatg atcaaagaag
     8281 caaaaatctt tggcgatttc ttcggactag gagatatctc tgacgtggaa aaaaaattgg
     8341 ttggacagaa atatgataaa gcatctctat caaaaatagt cagccaaatt gatgtgaaga
     8401 aatattttgg tgcgatagaa ccagaagaat tgcttacctt actttattga aaataaaaaa
     8461 tagcggaatc cacatatatg gattccgcta ttttttatac aggattcggg taatttcgag
     8521 agagttgaac agtgatccga tcaatgaaag tatctttttc ctgcgttagt gttcctgtgt
     8581 aacgatccgc tacgtctttc atcatcatta agtcaaaacg ttcctgatca tctaattctt
     8641 ctgtgatgcc tcgactaaat aggtttgtat cgtaatgtgc actatgttcg caacaaatga
     8701 cgaaatgttc ctcttgttcg tgtatcgaca aataaatttt tcgatacagt ggattttcga
     8761 tggcatgagt ttctctaaag gaatgctcta aagcgtggat caaaagttga gccagatcgt
     8821 catcgttgat aggaagttct tcgggaagat ctgcttggaa ggttatctga atattccgtt
     8881 tggcagctaa cttctggtaa cgcgctaaga taagatttgt cacctggtgg ttgcaaaaag
     8941 aacacagcat ttcgaaattt tttgcttctt ctaatatctt ttccacatag tttttagctt
     9001 ttgtttggtc cgtatgcatt aaatcttgca gattctccat ctcttggaca aattccaggc
     9061 gaagtgtatt tacttcttgg atatgctgtc gaagctgctc ataatgttgc tccaacaaat
     9121 catttttgat ttttaagaaa tctacttgtc tccgatcttt gtcggtattt aagatgtgat
     9181 cgattagatt gtagctgata ataacgatta gaatgataat atataaaatc gtagaccaat
     9241 tgatcgttgt ttgatagata cctaatgccg tttggatgta aatcaagcaa tggataatgg
     9301 ctaccaagac gatccaaggt gtacaagcta cataaaaacg gttattctta tatgcttcgc
     9361 caatgcatgc aagtgaagtg actaaagtgc ttataacact agcaatatta gcaatcggca
     9421 ttaattcagg aagttctgca ggagtaaaag ttgcataaag cagaacgccg ataaaaatca
     9481 aaagttggaa cgtacaaaaa attccgtacc attttttata gtaaaacatt cggctccaat
     9541 agtagcagat gatgaaagct gacgttaaga taataaataa atgagataaa aaagaatgaa
     9601 cgaatggttc aaaaagaata ccacttaaaa tatcttctga tacagcttca aatcctaatg
     9661 ccaaagcaaa gcaacttaag agaataagtg agtattcaag acgtttttgt ttatacatca
     9721 agtagatcgt atagaaaaag gtccctatag cgataaaaac agcgattatc atcgtcaata
     9781 cttgcggcac tgattgtgaa taaataaaac taatcaatgg tccagttgtt cctagataaa
     9841 ctttcggtgg cagtccagca tagttctgat aaggagatga gactgtaagg gtcaattttt
     9901 ttccgatata atttgctggt aaatctatca cagccaatga gagtccggga ttgctttctt
     9961 cctgataatc tttccgttgg tataaaatct tttcgcctag atatacagta atccattgat
    10021 ggtttccttt gattagtaaa tttgcttcgt ccaacggttt ttcaagtgtc gtttccataa
    10081 tgaatgtttc gtctttatcc acggtaggaa tcgtacgagt gtacttgctg tcaaacttaa
    10141 aatcaggatc atcttttgta tagaaaaccc acgaatcttt tatttctttc atttgattgc
    10201 tgtccgcagg agaaaaaata aaataaaaga aataagcaat tcctgttaaa aataacaatg
    10261 ataatataat gattatgctc cactttatac gtaaataaaa agattctttt ttattatata
    10321 tgttattaaa aaaagacata aaggtattcc
//
LOCUS       DAZULR010000071        10224 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.074, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000071 DAZULR010000000
VERSION     DAZULR010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10224
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.074"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            131..952
                     /gene="racE"
                     /locus_tag="ACG8ZV_002437"
     CDS             131..952
                     /gene="racE"
                     /locus_tag="ACG8ZV_002437"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HFS4997710.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            955..2310
                     /gene="rph"
                     /locus_tag="ACG8ZV_002438"
     CDS             955..2310
                     /gene="rph"
                     /locus_tag="ACG8ZV_002438"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0009022 - tRNA nucleotidyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HFS4997711.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            2311..2829
                     /locus_tag="ACG8ZV_002439"
     CDS             2311..2829
                     /locus_tag="ACG8ZV_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFS4997712.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            2936..3436
                     /gene="cbpB"
                     /locus_tag="ACG8ZV_002440"
     CDS             2936..3436
                     /gene="cbpB"
                     /locus_tag="ACG8ZV_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0180001 - cyclic-di-AMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP-binding protein CbpB"
                     /protein_id="HFS4997713.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(3716..4636)
                     /locus_tag="ACG8ZV_002441"
     CDS             complement(3716..4636)
                     /locus_tag="ACG8ZV_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HFS4997714.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            4762..5814
                     /locus_tag="ACG8ZV_002442"
     CDS             4762..5814
                     /locus_tag="ACG8ZV_002442"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HFS4997715.1"
                     /translation="MIKCGENNEGGKYMQIDWNNLGFSYIKTPWRFIAKWKDGQWEEG
                     ELTEDNYLTIHEGSPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLM
                     PMVPEKMFVDAVKQVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVF
                     CTPVGAYFKGGLKPTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCV
                     YLDPATHTKIEEVGAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIE
                     GDIFIDDLDQFAEAGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGI
                     QFGDIEAPEGWIEVVE"
     gene            complement(5924..6679)
                     /gene="fabI"
                     /locus_tag="ACG8ZV_002443"
     CDS             complement(5924..6679)
                     /gene="fabI"
                     /locus_tag="ACG8ZV_002443"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HFS4997716.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            6899..7339
                     /gene="fabZ"
                     /locus_tag="ACG8ZV_002444"
     CDS             6899..7339
                     /gene="fabZ"
                     /locus_tag="ACG8ZV_002444"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HFS4997717.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(7454..8215)
                     /locus_tag="ACG8ZV_002445"
     CDS             complement(7454..8215)
                     /locus_tag="ACG8ZV_002445"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFS4997718.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            8404..9498
                     /locus_tag="ACG8ZV_002446"
     CDS             8404..9498
                     /locus_tag="ACG8ZV_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HFS4997719.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            complement(9584..>10224)
                     /locus_tag="ACG8ZV_002447"
     CDS             complement(9584..>10224)
                     /locus_tag="ACG8ZV_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HFS4997720.1"
                     /translation="LYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPD
                     NYPDFNSEFGHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWF
                     SRFPKNFFKSITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILRRNG
                     LPKSMDFRKVNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
BASE COUNT         3306 a         1786 c         2131 g         3001 t
ORIGIN      
        1 aaagtcacaa ccgcttttcc tctttccatt cgaaaaaaag agatttcgat tgttttaagc
       61 aagtaagagc acttgaaaat tcacgctaaa aagtacacaa tagggaggat agaatttatt
      121 gaaaaaaagg atgatacgat tgacagataa tcgccctatc ggatttattg attcaggtgt
      181 cggcggcttg actgtagtaa aagaagccct gaaacaatta ccgaatgaaa atattttatt
      241 tgtaggagac acagcacgct gcccatatgg ccctagaccc gcggaacagg taatccagta
      301 tacttgggaa atgacggatt atctggtgga gcaaggaatc aagatgctgg tgatcgcctg
      361 caataccgca actgcggtgg ctttagaaga aatcaaagct gctctttcta ttccagtcat
      421 cggtgtgatc cttcccggta ctagagcggc agtaaaaaaa acacaaaata aacaagttgg
      481 cattatcggt acgattggta cggtaaaaag tcaagcttat gaaaaagcac tgaaagagaa
      541 agtaccagaa ttgactgtga caagtcttgc ttgtcccaaa tttgtttcag ttgtcgaaag
      601 taatgaatac cattcatcgg tggcgaaaaa aattgtggca gaaacattag ctcctttaac
      661 cactaaaaaa atcgatacat tgattttggg atgcacccat tatccattat tacgccccat
      721 cattcaaaat gtaatgggag aaaatgttca actgatcgat tctggagcag aaacagtagg
      781 tgaagtatct atgctgttag attatttcaa tttgagcaat tcaccgcaaa atggtcggac
      841 attatgccag ttttatacaa ctggctctgc caaacttttc gaggaaatag ctgaagactg
      901 gcttggaatc ggacacttaa atgtagaaca tatcgaattg ggaggaaaat aaggatgcgt
      961 catgacggga gaaaagccca agagcttcgc aaactggagc ttcaaacaaa tgttttcaaa
     1021 tatccagaag gatcggtagt gatccgtttt ggtgatacaa cagttatttg ttctgcaaca
     1081 atagaaaatt ctgttccccc ttttttgaga gaaacaggaa caggatgggt gacagcagaa
     1141 tatagtatgc tgcctcgagc aacgagtacg agaaatcgta gagaaagcag caaagggaaa
     1201 ctttctggta gaacaatgga aatccagcgt cttattggtc gttccttgcg tgcagtagta
     1261 gacttggaaa aattaggaga acgtagtatc atcgtagact gcgatgtgat ccaagcggat
     1321 ggcggtacta gaacagcaag tatcactggg gcatttgtgg cattgaaatt agccattgaa
     1381 aaacttttaa gagaaaaaga attgtcagaa gatccaataa aagaacatct tgctgcagtt
     1441 agcgtaggaa tcttaccaga tgggacttgc gtcacagatt tggattacca agaagattcc
     1501 gcagcacttg tagacatgaa tcttgtaatg acagaatctg gaaaattcgt ggagattcaa
     1561 ggaactggag aagaagcaac gtttgatggt gaacagttga atgaaatgct cttttttgga
     1621 aaaaacgcga ttgaagattt gatcaaagag caaaaacatg ctttgctaac agagtttgct
     1681 caaaatgatg agcggataga agaaacaaaa acaatcatca ttgcgacaag aaatccagga
     1741 aaagcagaag agtttcgaaa tatgttcaaa gaagcgggat atcatgtaaa aacattactt
     1801 gactatcctg aattgccaga tgtggaagaa actggcagca catttgaaga aaatgcccga
     1861 ttaaaagcag aaacgattgc acaattgctt gatcagccag tcttagcaga tgattcaggt
     1921 ttgaaagtgg atgctttagg cggtatgcca ggaatctatt ctgcacgttt tgcaggggaa
     1981 caaaaaagtg atgcggggaa taacgccaaa ttattatatg aattgacaga tgtgccggat
     2041 gaaaaaagaa cagcacaatt ccattgtacg ttagtattcg cggcacccaa aaaagacagc
     2101 cttgtagtag aagcggaatg gcccggtcga gtagcccgta taccatctgg cgaaaatggc
     2161 tttgggtatg atcctttatt tatcccagaa ggtaagaaac aaacagcagc agaattatcg
     2221 agcgaagaaa aaaacaagat cagtcatcgg gctcaagcaa tgaaaaaatt gagtgccgag
     2281 tggaaacaat ggctggaagg agagagatag atgcggtatt tagtagtaag tgataatcat
     2341 ggagacagag atatcctcgt tgacttagta gatcgttatc gttctgaagt ggatatcttt
     2401 ttccattgtg gtgattcgga attagaagct tctgacccat tatgggatac attccaagtg
     2461 gttcaaggta attgtgatta tggaccagga ttcgaacaga aaaaagtgat ccaaactggt
     2521 caggatacag tattcatgac tcacggtcat ttatcgaatg tccgatttgg tttgacacag
     2581 ttagcaatcg aagctcgagc tgcaactgcc gatatggtgt tttttggtca tacccatcaa
     2641 ataggctgtg agatggatca gaaaatcctg tttttgaatc ctggtagcat ttctcagcct
     2701 agaggcccga tccaaatccc atcatatgct cttatcgaaa gtttagatga ccaaatttct
     2761 gttcaatact ataaccgtgc ccatcaggca gttgaagagt tggccttttc tttttcgaga
     2821 gagcgctgaa taaaaaaact ctaattttta ataaaaataa gctttatttt atgaattttg
     2881 catccggttt cggtaaaata gtagtgttga atgaaataga aatggaggcc atcagatgat
     2941 tggacctata gtaagagaaa tgctgctgga aaatcaggaa acgtttttga ttcctgcaga
     3001 aaatgtggca aatgttatgt atcatcatcc attgtcccat ggtttacttg tgttatcgaa
     3061 ggtcggttat tccaaaattc ctgtattagg aaaagatgat cactttgtag gactagtaag
     3121 tttatcagat gtggtcaata aaatgattga cttgcaaaca atcagcatgg acccgttaga
     3181 aggactaacg gttgctgatg tgacagaaac agatgttccg acaattgatg aaaattggga
     3241 actagaagaa gtactccatt tgttagtcga ttcgcctttt ttaccggttg tcacagaaga
     3301 tcggattttc aaaggaatca ttacaagaaa agagctgctt aaagccgtaa acttcatggt
     3361 gcatgaatta gaacgtcgta atatattgtc tccgaaaatc gaagaattaa aagaacaaat
     3421 cgatatcgtg agctaaagaa cgagaaacta aaagataatc aaaaaataag tagaaaaaac
     3481 agcgtaccag ttttgacttt atcttgaaaa agaggctggg acaaaagcgt ttaactccaa
     3541 gaaataagaa ggaattcacg aaaattgctt ttcaaatttt tgtgaatttc agcttatttc
     3601 cgaaggagtt gcttctgctt ccgccgttta tacgtgttta gagcgtggga caaaagtgtt
     3661 ctttactttt gtcccacgct ctttttagtg agattcgttg catcgtttgt ccaaattatt
     3721 ttccgacagc aattggactg ttcggaatcg tgaaaccaga agctgtcaat tctttgacat
     3781 aggagctcaa gaactcttct tttaaggcat attgttttcc gttcaatgcg tagcagaccg
     3841 tacgaatcgc aaaattgctg tttccaagat ccactaatcc aaagatagaa ggttcagttt
     3901 ggagctcttc ttggtatttt tcagctaatg tacgatttac tcgatcaatg atctcataga
     3961 ttttgtcata tccttcttca ggaacaatcc gaatatctaa aagtacttgc atatttgcac
     4021 gagagagatt gctgatcgtg gtgatgtttc gattcgggat gaaatggaca gtaccatccg
     4081 ttgctttcag ctgaagggta cggataccaa cagatacgac ggttccttca atcgttaagt
     4141 ttgctagctt gatgtagtcc ccaacatcca tctgttgttc catgataata aaaaatccgg
     4201 taataacatc actcatgaac ccttgggcac caagaccgat tgccacacct gcaattccgg
     4261 caccagccaa aagtgatccg atcggcacac cgatagcaga taaaattgca tagataaaaa
     4321 agaaaccaag ggtataatga aaaatagtat ttaaaagact atgtaaagtc tttaagcggc
     4381 tctcgtttag aatggctttt ttagaatact gattaaaaga cttatcaatc agatattttc
     4441 ccacacggtg aagaatccaa aaaaggacga tcaaaaaaat cagatataaa cttttttgga
     4501 taaaggcagc caaaatggcg tcccaatcaa tcccgtccca aaaccgctga aacgcattta
     4561 ctttgctgac agcttgatct gtcaatgtct cgccagaaga gtctgtcgta ccggcagttg
     4621 ctaataatga aaacataaaa tcctcttttc taaaatttga ttctttctgt attgtaccaa
     4681 gaagttttca aaaaaggaaa tagcaaaaat aactataatg aaggaaaaaa gctgaaaata
     4741 aaatgacaaa taatatggat aatgataaaa tgtggagaaa ataacgaagg tggtaagtat
     4801 atgcaaatcg attggaacaa tctaggtttt tcttatatca aaactccttg gcgttttatt
     4861 gccaaatgga aagacggaca atgggaagaa ggagaattga cagaagataa ttacctgacg
     4921 attcatgaag gctctccagc gcttcattat ggtcagcaat gttttgaagg tctaaaagct
     4981 tatcgtcgaa aagacggcaa ggtcaatctc tttcgacctg aacaaaatag tcgacggatg
     5041 aatcaaagtg ctagacgatt gctgatgcca atggtccctg aaaagatgtt cgttgatgct
     5101 gtcaagcaag tggtaaaagc aaatgaagat tttgtgccgc cctatggaac aggcgctaca
     5161 ttatacttgc gccctttact gattggggtc ggtgaaaaca ttggtgtcca tccagctcca
     5221 gaatatttat ttgtcgtctt ctgtacgcca gtaggagcgt atttcaaagg tggactaaaa
     5281 ccaacgaatt ttattgtatc tgattacgat cgtgctgctc ctaaggggac tggtgcagca
     5341 aaagtcggcg gaaattacgc agcgagttta cttccaggaa cagaagcaaa agaactggat
     5401 tactcagatt gtgtttatct tgatccagcc acacatacga aaatcgaaga agtaggtgca
     5461 gcaaatttct ttggaattac aaaagacgga aaattcatca ctccgcaatc gccctctatc
     5521 ttaccaagta tcacgaaata ttccttgttg cagttagctg aagaacgact aggactgcaa
     5581 gcaattgaag gagatatttt cattgatgat ctagatcaat ttgcagaagc tggtgcatgt
     5641 ggtacagcgg ctgttatttc tccaatcggt gggatttatc acaataacaa tcttcatgta
     5701 ttttatagtg aaacggaagt aggaccagta acaaaacggt tgtatgatga attgacaggt
     5761 attcaatttg gagacataga agcaccagaa ggctggattg aagtcgtgga ataatttcaa
     5821 agtaatgagt tgaaaaaaac gtaaaaagaa aaaatcagga agagacttta aaaagttttt
     5881 tcctgatttt tatatgtttt actttaaaga atgcaacaaa agtttatgaa agatggacac
     5941 ctttgtcaac gtagataata tcaccgatga ttccgctgga aagtgggctg attaagaaag
     6001 cacaagcatt accgacttct tcgatcgtca caccttgctg atcaggcgta cgagattcag
     6061 ataactggat cagtttttga tagtctttaa cacctgtgac agctaatgtt ttgattgccc
     6121 cagctgagat tccattgacc cgaattcctt taggcgagaa ctcagctgcc aaataacgga
     6181 tagcagcttc aagagaagct ttcgcaatac ccatcatgtt ataattcggg attgcgcgtt
     6241 ctgaacctag ataagtcatg ctaacgatcc cgctgtttgg tgcaagaaac ggttgtgcgt
     6301 attttgatac agcaattaaa gagtagctgc tgatatcttg agctaattga tagccgtctc
     6361 tggaaatatc agacacattt ccggacaatt cttctttgtt ggcgtaagca actgcatgga
     6421 caaggccgtg gatctcccca gcatattcac cgatggcatt cattgctttt tcgatgcttt
     6481 cgtcgctaga aacatcacat tctacagtga atgcttcttc gccgaccaat ttgactaatg
     6541 attttttcat tcgttcattt tggtaagtat agataatttc tgccccttgt ttcaacattg
     6601 cttcagcaca accccaagca atgctttttt tgttagcgac gcccataatg acgatttttt
     6661 ttccttctag aaatgacata atgactctcc tttgtttctg ataaaaattt gatagtcgta
     6721 aaaaaataga gaataatagc taaaataact tcttgatttc ttaattatta gtcaaaatgt
     6781 tttgattgtc aaactatttt ttcttaaatt aaaaaaagat tgctaaatat ttaggaatat
     6841 gatactttga tagtcaaagt aatgaaaatg gcaattgcct gaaagaagga gtttaattat
     6901 gtcttacgta ttatctgcta ctgaagtaat ggaattgatt cctaatcgtt atcctatttg
     6961 ttatattgat tatgtagata ctttagaacc aggaaaaaag atcgttgcga caaaaaatgt
     7021 aacaatcaat gaagattttt tccaaggtca ctttcctgac aatccagtga tgccgggtgc
     7081 gttgattcta gaaacactgg cacaagcagg ttcgatactt atcctaaaat cagaagagtt
     7141 tctaggaaaa agagcttata tcggtgggat caataaggcc aaattccgtc aaaaagttgt
     7201 tccaggagat gtgctgaaat gtcattttga aatcaccaaa atgaagggat cagtcggtac
     7261 agcgttatct gcagcatatg tagatgataa aaaagtctgt gagtgcgagt tcacgttcat
     7321 cgtcaaccaa aatgcttgac tataaaacct gatatagcaa aacaaaagga agcttacttg
     7381 ctttttatgt aaaaagaaga cgcctgaatc ctagcatacg ttgtcatcta tgcaggattc
     7441 agacgttatt tttttatttt tgttttgctt cttgcagtat attgatttta tcgattttta
     7501 cttcttcttt tggtttgtct gaactatctg tttcgatatt tgcaatagca tccacgacat
     7561 ccattccttc aatcacttgg ccgaagacag tataatggcc atctagtgaa ggataaccgc
     7621 cgtttttata agcgtcgatg attgcttgag gatagtcgtc ttttaaaaga ccatcatgca
     7681 tatcatctgt attttgaacg ataaagaact ggctgccgtt actgttagga tcttgtgagc
     7741 gagccataga taacgcacct cttatattat aaaggtggtt gttgatctct gtttcaaatc
     7801 cttctcccca aatgctttcc cctccagtgc catcgccttt aggatcgcca ccttggatca
     7861 tgaaatcttt gatgacgcga tggaaagtca gtccgttgta gtaaccgtct tttgcatgtg
     7921 tcataaagtt ttcaaccgct tttggtgcgt gttcgggaaa taatttgatt ttgattgtgc
     7981 ctttattcgt caccatttcg accagatctt cattttcggc gacatctttc gtcaattgtg
     8041 gtaattccaa tgcgttcaaa tcgacgctac tggcagtcgt gctttccgca gtagatgtac
     8101 tttttgaact ttctgtagac gaactagaag aagtcgtgtt gtttgcagaa caaccagcag
     8161 caaacagcaa tgctgctgct aaactaatac ttaaaataac tttatttttc ttcataactg
     8221 ttcctttcca atttactatt ttgttatctt taatgataac aaaatagagg gaaaatacct
     8281 acttaaatta ttggaattta tcatttattt taaaagaaaa agaaaaggtg tagaccattt
     8341 actttgtgtt tgctataatg taagtggata caaaaacgaa aagatgcagg aggaaatggt
     8401 aatatgggaa aattaggaat ctcgatttat ccagaacggt caacatttga aaaggacaaa
     8461 gcgtacttgg atttagctca taagtatggg tataaacggg tttttaccag tttgctgcag
     8521 atcaatgatg ataaagaaaa agttctttca gaatttaaag aagtagttga ttacgcgaat
     8581 agcctaggca tggaagtaat ggttgatatc aatccagcgt tatttgaaca gttggagatt
     8641 tcttacgatg acttatcttt tttccataag atgggtgcct acggggtccg cttagatatc
     8701 ggattcacag gagcagaaga agcaaaaatg acgcgcaatc cttttggtat caaaatcgag
     8761 atcaatatga gttcgggcac gaattacgtt gacaacatca tgagttattc gccaaacacg
     8821 gataatttat taggttctca taatttttat cctcatcgat actctggttt aggatacgaa
     8881 cactttgttt tttgttcaga aaaattcaga aaatataatt tgaatacgat ggcattcgtc
     8941 aattcgcaat ctgctgagtt tggcccttgg cctacgcaag atggcttgtg cacgctggaa
     9001 gaccaccgag atcttgaaat tgcgacacaa gtgaagcatt taatccttac aggattgatt
     9061 gatgatattt ctattggaaa tgcgtacgca agtgaagaag aattgaaaga aatggcagaa
     9121 gcatttaacg cggattatcc aacattgaaa gtagatacgg aagaaggtat tacagaaaac
     9181 gaacgaatct gcttgtttga taaccttcat agttatcgag gggatcgctc agaatatatc
     9241 cttcgttcaa cgatgactcg tgtatactac aaagataaag atttcccgcc tcataatacg
     9301 cgagatatgc atcatgggga tgtactgatt gacaatgaag ggtacggtca atacaaagga
     9361 gaaacacaaa tcgccttgaa ggatatgaaa aacgacggac gtgtcaatgt tgtaggaaga
     9421 atctccgatg acgaattatt cctccttgac tttttgaaac catggtcaag ctttaaatta
     9481 attgaaaata aaaaatagat aattagttat tgcagaaata atccgctaga aatagccagt
     9541 tatttctgct tttttatttt gtttttttat aggttatgat ttgtcaaatt aagctagaat
     9601 aaaatgcttc ttgtacatag ctcaaaaata tttcgattgg tgttctgtaa ttcaatgatt
     9661 ttcttggaat atgattacgt tgattgctga cactggaaat aaatgtctga ttcacttttc
     9721 taaaatccat tgatttcggc agtccattac gacgcagaat cccgttagaa ttctcgttta
     9781 atgggcgttg agaaggtgtt ccagggtccg caaaatatat atcaatatca tgttggttac
     9841 taatggcttt ccagttagaa aattcttttc cacagtcaaa cgtaatagat ttaaagaagt
     9901 ttttagggaa gcgagaaaac cattgattaa gggcagtttc aatatctaat gccttacggc
     9961 cgttgggttt aatcgtgata atgactttag ataatctttc aactaaagta atgacggcac
    10021 ttttatgatg aatgccaacg atcgtatcac cttcaaggtg accaaactca gaattgaaat
    10081 caggataatt atcaggtcga tcatggattg agcgctgata ctgttgtttt ccccgttttt
    10141 cctgatggcc attgggtttt cttttacctt tcatcggtag tgtgtcaata tcaaatattc
    10201 ctttagaaaa taaacgataa agtg
//
LOCUS       DAZULR010000072         9934 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.075, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000072 DAZULR010000000
VERSION     DAZULR010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9934)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9934)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9934
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.075"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            23..982
                     /locus_tag="ACG8ZV_002448"
     CDS             23..982
                     /locus_tag="ACG8ZV_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFS4997721.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     VDEFFIQSVASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
     gene            1459..1659
                     /locus_tag="ACG8ZV_002449"
                     /pseudo
     CDS             1459..1659
                     /locus_tag="ACG8ZV_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298761.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2371..2976)
                     /locus_tag="ACG8ZV_002450"
     CDS             complement(2371..2976)
                     /locus_tag="ACG8ZV_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFS4997722.1"
                     /translation="MAKIGYIRVSSQDQNLDRQLAMMEDLNIDKLFQEKASGKDIQRP
                     EFQKLLNYIREGDCVIVASLDRLGRDYEDIKNTVTFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAKKAGRYKGRPIEYSENSTDPQ
                     KRLVFKTVVDMLNQGVPVAEIAKENGLSRPTIYKIKKANDL"
     gene            3158..3493
                     /locus_tag="ACG8ZV_002451"
                     /pseudo
     CDS             3158..3493
                     /locus_tag="ACG8ZV_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387932.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
     gene            3658..3873
                     /locus_tag="ACG8ZV_002452"
                     /pseudo
     CDS             3658..3873
                     /locus_tag="ACG8ZV_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397514.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            4011..4982
                     /locus_tag="ACG8ZV_002453"
     CDS             4011..4982
                     /locus_tag="ACG8ZV_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFS4997723.1"
                     /translation="MKTTMKDVAALAGVGVGTVSRVINGVKVKEVTKEKVMAAISELN
                     YEPDEYARGMKTNSSNTIALILPTIWHPFFSEFAYYVEEALSQKNYKLFLCNANGSAE
                     KEKEYIQMVKQSKVDGIIGITYSDIDKYVSSNLPFVSIDRHFSEQVSYVTADNYLGGQ
                     IAAQELLTRNCKNLCYVGGVSPYPNETNNRKAGFYNICEENKIAVKVLDMPEPISNLE
                     EQLLAFFSDNPEIDSIFTINDFMALDVIKAQKKLGKEAPKDFQIIGFDGVKLSLQKDY
                     LLSTIVQPIEEMAKVSVETLMAMILNEEPPKRVVVPVFFHAGETTKE"
     gene            5122..6435
                     /locus_tag="ACG8ZV_002454"
     CDS             5122..6435
                     /locus_tag="ACG8ZV_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HFS4997724.1"
                     /translation="MKKRMLAIAAILALTAGGLAGCGSKEKSSGSSDPGEIKIWVQFS
                     DETPEGKAWAEIVNNFNDEYEGEYKAVTEYIPRSGSGGGYEDKVNAAITTNTLPDVIT
                     LDGPNTAAYAHSGVIAPLDDYLKDADMDDVLDSIIQQGTYDGKMYAFGFSESSVGVYY
                     NKSLFKDAGITEDQLPTLEDPWTWTEFQAICQKLTDKYKTPAIDMQMASGDEMLTYAY
                     TPFIWSNGGDVVNADGTKAEDYFNGKKSVEALEFIQELVEKGYTTISPIEKGFETGKY
                     AMMLSGSWTMADLEENYQEIDYGILPYPVSDATGELVSPTGSWQLAMTEKTEKKDASA
                     AFIKFATSTESSRIMSLGNSVLPIRNSTVDLIKDEVSEGMQVLIKQNQLSGHARPVVV
                     AYPQVSRAFQQAVQDISYFEENPDVQKVADSRAAEMQQAIDTSLK"
     gene            6478..7344
                     /locus_tag="ACG8ZV_002455"
     CDS             6478..7344
                     /locus_tag="ACG8ZV_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4997725.1"
                     /translation="MKDNLIGYGFLAPALLLLTIFLIIPVIMVIYYAFTDYYLLTPDA
                     RQFIGLENFKRLFADPIFVKSIWNTAKFVVWIIPVQIGAALGMALIINKNRKGNIFFK
                     VAFFAPVVMSLVVISILWLYLLNPNEGLVNTLFAKIGIASQPFLTSPKQAMYTLVFVS
                     AWQGAGYQMLLFLGGMQNIPQDVYEAAEIDGFSKFQQFRYITMPLLKPTAIFILLTTL
                     ISAFKLIIQPMVMTQGGPMNSTMTMVYYIYQTGFTDRMVGYSSSIALIFTTMIGLITI
                     AQRKLVKEDDPA"
     gene            7341..8189
                     /locus_tag="ACG8ZV_002456"
     CDS             7341..8189
                     /locus_tag="ACG8ZV_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFS4997726.1"
                     /translation="MTKKFGPLMIVEYCLLFLLAALFIFPMLWMVVSSMKPEADVYQN
                     LASFKAFLPSLNPANWFKTYQEVISRFSVGTYLLNSIFYGLTFACGSIIVNSLAGFAF
                     AKVNFSGKKIIFGALLALLIVPMETVLIPQFTIVNSLGLVNTRLAVILPAMASAFNIY
                     LFRNFFIAIPEEIIESAKLDGANIVKIFFHIMLPMSKPAIATVGVLSFISSWNDYIWP
                     LMVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTIATIPLIIVYIVAQKYILQGLGG
                     SGTGIK"
     gene            8203..9675
                     /locus_tag="ACG8ZV_002457"
     CDS             8203..9675
                     /locus_tag="ACG8ZV_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HFS4997727.1"
                     /translation="MLQKLLKANEFIEKNAQTVNQEYRNKFHLMAPIGWMNDPNGFVY
                     YQEEYHLFYQYYPYDSIWGPMHWGHAKSKDLIHWEHLPVALAPGESYDKEGCFSGSAI
                     EKDGKLYLIYTGHNVVEGQVRQVQCLAVSEDGIHFEKYAGNPIIAEDHLASVATTEDF
                     RDPKVFQRKEDYFTVVATKTADARGQIVMFHSKDLLTWEFYSVLLEGTPEQGIVWECP
                     DLFELDGKEVLILSPIQMTPQGNAYQNTNSTVAFIGTVDWQTGKFLVENFHEIDGGLD
                     FYAPQTCENEAGQRIMIAWMQMWQRKIPTNDLGHGWSGSMTLPRELRVADNQLLQRPV
                     SSIYQVIDPQERIEWAKTEENRFLLKDLVYDQHYLRLEINLKQATKLELHYAKGPDHT
                     LLLNYDVERECFTASREHMPYDLSGAEKEVLKKRSVTIPLENNCLTIEIFRDTSAIEL
                     FLNDRLTMSTTFYETEKGQDFLLLADSEVTFSLESGLINL"
     gene            9692..>9934
                     /locus_tag="ACG8ZV_002458"
     CDS             9692..>9934
                     /locus_tag="ACG8ZV_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFS4997728.1"
                     /translation="MIYGSIEAGGTKFVCAISDEEMTIKERVSFPTTTPEETIPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPK"
BASE COUNT         3171 a         1682 c         2016 g         3065 t
ORIGIN      
        1 gaattataag gagtgagtac aaatgaccta tacccatctt acaacggatg aacttgtaat
       61 aatagagtct tatttcaaaa tgaatcaatc tgttgctaaa actgcccatt gcttgaatcg
      121 ttcaagacaa acgatccata aagtatatct gttcttcaag caaggaaaat cagccttaga
      181 atattatcaa cagtataaga aaaacaaatc aaactgtggt agacgtccgc ttgttttacc
      241 cgaggaacaa tcagaatata ttcaaagaaa ggttgttcaa ggatggacac ccgatgtgat
      301 tgttggtcgt gcagcgtttc ctattagttg ttctgctcgt accatttatc gtatgttcaa
      361 aaaggggcta tttgattctt ctgacttacc gatgaaaggc aagcgtaaac cgaatggaca
      421 tcaagaaaga cgtggaaaac aaactttccg ccgctctatt catgaacgtg aaaaggatta
      481 tagccaattc tcaaatgagt ttggtcacct tgaaggtgac actatcgtag gtctgaaaca
      541 taaaagtgct gtaattacct tagttgaacg attatcaaaa gttatcatca cattgaaacc
      601 gtgtggtaga caagcgattg atattgaaaa aaaattaaat caatggtttg aatctgtacc
      661 gaaaaaccta ttcaaatcca tcacttttga ttgtggaaag gaattttcaa attggaaaca
      721 gatcagtaat gtcaatgata ttgccattta tttcgctgat ccaggaacgc cgtctcaaag
      781 aggcctaaac gagaattcta acggattgtt acgtagagat ggtttattga aatctatgga
      841 tttcaattca gtagatgaat tttttattca atctgtcgca tctaaacgaa ataatattcc
      901 tagaaaatca ctggattatc gaacaccttt ggaagtattt ttgagttacg taagtattga
      961 tgatctgtct aacttaattt gacaattaag acatttaaaa agaaaagtga cagataggaa
     1021 taaaaactta ttaaatgtag ttatgatctg ttatatttca tttctaatac taggtcttcc
     1081 acaagcagtg tttcctgaaa tgttttctgg agactggggt attgtcagct attctatatt
     1141 aacattgatt gctatggttt taggtacttc attttataat gcttttgtaa gtaagcatgt
     1201 tgaggaatat gaagtattaa tgtacttaaa agagaaaaaa acaagtaatt aatatgagaa
     1261 caccacgcat agtttttatt ttgagatatt ctagaatgaa acacattaag aacgaaagca
     1321 aagcaaaaga cgccagaact tctactacct tctaagtttt ttcatatttg tttgttatgc
     1381 tatacataga tctgcataat tagacttgcg ctgcccgtta ttgaagtttc aggcagcgct
     1441 ctttttgggg gatcgataat ggaagaagaa aaaatatttg agaaacgctg gcagctagca
     1501 tcaagtgaac aaagagcaag atacaataat ttgatcacct cctaccccac tgttgactag
     1561 acatataagg aaaagaaata cttactttgg ctgtgccagt tagatataga tacctttgaa
     1621 acatttgaag tgatcctaga taaaattaaa cagaattgat cagaaacaag cgaagccttc
     1681 tctcggttcg cttgttttgc tatttattag ttggctcagg gcaactctaa gctcgtttga
     1741 aagaaaaccg atggataatc cccttgtttg taccacttta gaatacatgg atgtacgtat
     1801 tgccattgac tcctattagt tactgaaaaa aaatttaaac aagttgagta ttgcagataa
     1861 atagctccag tgaggtgaat aactgctcca ctcaaggcaa tagatagctc catccagggc
     1921 aacaaactgc tccactttca tatttaatag atgaataacc ttctgtataa tagaaaggca
     1981 tacctttcgg tatgacaact tatacagaat gttattttat tggttcacta tcgaaaaatt
     2041 ttggagcttt atttttccgg tatttctcaa cgaacgatta gtttaactgt gggaagctcc
     2101 agacatacga ttcgagaagt tacttctcga gcagacagga agggggtgac tgaactaacc
     2161 gctgatatga gcgatacttg gctgtaggaa tatctttttc cggaaaaaca aacaacagca
     2221 cgaggttacc ttcctgtaga ctgggaatat gttcataaag aactaatgaa aaagaatatg
     2281 acattgaaac tccttcatag agaatatggg gtacatggaa catagaaacg aaaatgcacg
     2341 gtagaaaagc gaatgaatat agtataaatt ctacaaatca ttcgctttct ttattttata
     2401 tatggttggt cgagagagac cattttcttt ggcaatttct gcaactggaa ctccttgatt
     2461 taacatgtcc accacagttt taaagactaa tcgtttttgc ggatctgttg agttctcaga
     2521 atattcaatt ggtcgcccct tatatcgacc agcttttttg gccaataata ctccttgccg
     2581 ctgacgttca cggattttct cacgttcgtt ttgtgcaata taacttagca atgataaaaa
     2641 catatcgaac atagcagtat ctaggagttc atttccagta ttaaaatcta aaaactgtgc
     2701 atctagtatt tttaatgcta cttttttctg tttcataaag gtaactgtat tttttatgtc
     2761 ttcataatct ctgcctaggc gatccagtga tgcaacaatg acacaatcac cttctcggat
     2821 ataatttagt aatttttgaa actcaggtcg ctggatatct ttaccactgg ctttttcttg
     2881 gaataattta tcaatgttaa ggtcttccat cattgccaat tgtcgatcta aattttgatc
     2941 ttgtgaagac actctaatat atccaatttt tgccataaaa actcctttta aaaaatgata
     3001 taatttacat gtaaaattta cttgtagttt tactgttatc atagcatttt taaaaataaa
     3061 ttttaagtct acttataatt tactttggag gttttgaatg aatgaaatta agcgcaataa
     3121 aaattctttt ggtgtttatt taggagagcc tagctcggaa cagttaaata aaggtgaagc
     3181 tcgtcatgct ctatgtcgaa atatatttta tggtagaaaa ggcaaacttt atcaaactta
     3241 ttacgacggt atggaggaac agctcaacgc attaggatta gtaactaatg ctatcatata
     3301 ttggaattca ctatatttag aaaaagtctt tgaacaaatt aaaacggaag ggttcgactg
     3361 ttccgaagaa gtgttacgca agcaatttcc attaattagt gatcacatta attttgttgg
     3421 caaatatagt ttccgctatg aaaaagaatt atcgaatgga atactacgtc cgttaaatat
     3481 agagaattat tgagaatgtt cgtcttttgg ttcctaccgt gcattttcgc acggatgttc
     3541 cagatactat ttttgaatgt ataaaattga aaacacaaga atactaataa atcaacgatt
     3601 cttgtgtttt taatttttca ctaccgtgca ttttcgtttc tatgttccat gtaccccaat
     3661 cttgaaaaat taattaaaga cttagataaa gccattgacg acttagtcgt ggtgctaccg
     3721 gagtatcaat gtttaaccag tatcccaggt attggtcctg tttaggctgc tggaatactc
     3781 gctgaaattg gtccaattga acgtttttct gatgaaataa aattgacaaa gtatgccggc
     3841 ctatattggc gacagagtca atccggtaaa tctgaatacg aaaatttttt tacgaaaagc
     3901 ttcacgtcta atatctattt taaaataaaa atattcctgc taatttggaa tcgtttcctt
     3961 cttttggtat aataatacct gaaattcttt tgagaggagt tgttcgtgaa gtgaaaacta
     4021 ctatgaagga tgttgctgcg ttagcaggag ttggtgtggg tacggtatct agagtaataa
     4081 atggagtaaa ggtgaaagag gttaccaaag aaaaagtaat ggctgcaatt agtgagctta
     4141 attatgagcc tgatgaatat gccagaggta tgaaaacgaa tagtagcaat acaatagctc
     4201 ttattttacc tacgatttgg catcccttct tttccgagtt tgcctactat gtagaggaag
     4261 ctctcagcca aaaaaattat aagctttttt tgtgtaatgc gaacggcagt gcggaaaaag
     4321 aaaaagaata tatccaaatg gtcaagcaga gtaaagtaga cggaattata ggtattacct
     4381 attcagacat tgataaatat gtatcatcaa atttaccatt tgtcagtata gaccgccatt
     4441 tttcggaaca ggtttcttat gtaacggcag ataattattt aggtgggcaa attgccgctc
     4501 aagaactact tactcgtaac tgtaaaaact tgtgctatgt tgggggtgtt tcaccttacc
     4561 ctaacgaaac aaacaatcgt aaagctggtt tttacaatat ttgtgaggaa aataaaatag
     4621 ctgtgaaggt attggatatg cctgaaccaa ttagcaattt agaggaacaa ttgctcgctt
     4681 ttttttcgga taatcctgaa attgatagca tttttaccat caatgatttc atggctttgg
     4741 atgtgataaa agcccaaaaa aaactaggga aggaagcacc taaggatttt caaattattg
     4801 gttttgatgg agtcaagcta tcgttgcaaa aagactattt actatcaacg attgtacagc
     4861 cgatagagga aatggccaag gtttcagtag aaacactcat ggcgatgatt ttaaatgaag
     4921 aaccgcctaa gcgtgtggta gtaccggttt tctttcacgc tggagagacg actaaagagt
     4981 aaaaaaccgg tttataacga tttttttgag ataggttgac agaaagtgat ttcaatgata
     5041 tcttaaaacc aattaattgg aaacgttacc aattaattga aaaataaaac ggaaacgttt
     5101 caaaaaatag gaggaacatc gatgaaaaag agaatgttag caattgcagc aattttagca
     5161 ttaacagctg gaggacttgc aggatgtggc agtaaggaga aaagttcagg tagcagtgat
     5221 ccaggagaaa ttaagatttg ggttcagttt tctgatgaaa cgcctgaagg aaaagcttgg
     5281 gcagagattg tgaacaattt taatgatgaa tacgagggtg aatataaagc tgttactgag
     5341 tatattcctc gtagcggaag cggcggtgga tatgaggata aagtaaatgc tgcaattaca
     5401 accaataccc ttcctgatgt tattacgtta gatggaccga atactgcagc ttatgctcat
     5461 tcaggagtca ttgctccatt agatgattat ttgaaagatg cggacatgga tgatgtatta
     5521 gacagcatta ttcagcaagg aacctacgat ggcaaaatgt atgcgtttgg tttctcagag
     5581 tccagtgtgg gtgtctatta caataagtcg ctgttcaaag atgctggaat tacagaagat
     5641 caattgccga cgttagaaga tccttggact tggacggaat ttcaagcaat ttgccaaaag
     5701 ctgactgata aatacaaaac gcctgcaatt gatatgcaaa tggcgtcggg agacgaaatg
     5761 ctgacctacg catatacacc atttatatgg tcgaatggcg gcgatgtcgt taatgctgat
     5821 ggaaccaaag ccgaagacta ttttaacggt aaaaaatccg ttgaagcgtt ggaatttatt
     5881 caagaattgg ttgaaaaagg ttacaccaca atcagtccta ttgaaaaagg atttgaaact
     5941 ggcaaatatg ccatgatgct gagcggttct tggacaatgg cagatttaga ggaaaactat
     6001 caagagattg attatggtat tttgccttac cccgtttcag atgcaactgg ggagttagtt
     6061 tcaccaaccg gaagctggca gttagcaatg actgagaaaa cagagaaaaa ggatgcttct
     6121 gcggccttta ttaagtttgc aaccagtaca gaatctagtc gtattatgag tttagggaac
     6181 agtgttctac ctatcagaaa ttcaacagtt gatttaatta aagatgaagt gtcggaagga
     6241 atgcaggtat taattaagca aaaccaactt tctggacatg cccgcccagt ggttgtagct
     6301 tatccgcaag tatctagagc attccaacaa gcagttcaag atattagcta cttcgaggaa
     6361 aacccagatg tacaaaaagt agcagatagt cgcgctgctg aaatgcaaca ggcaattgat
     6421 acttcactaa aatagaagtt tctaaagggg gccaatcaag tgttaaaaaa accgacaatg
     6481 aaagacaatt tgataggtta cggctttcta gcgccagctt tgctgctgct gacgattttt
     6541 ctgatcatac ccgtaatcat ggtaatttat tatgccttta ctgattatta tttgttaacg
     6601 ccagatgcta gacaatttat cggcttagaa aattttaagc gactgttcgc tgatccaatt
     6661 tttgtaaaaa gtatttggaa cacggctaaa tttgttgttt ggattattcc ggtccaaata
     6721 ggggcagctt taggaatggc acttattatc aacaaaaatc gtaaaggaaa tatctttttt
     6781 aaagtagcct tttttgcgcc agtcgtgatg tccttagtcg ttatttcgat tttatggttg
     6841 tacttgttaa atcctaatga aggtctggtt aatacgctat ttgcaaagat tggaattgct
     6901 tcgcagcctt ttttgactag tcccaaacaa gcaatgtata cgcttgtttt cgtatcggca
     6961 tggcaaggtg caggatatca gatgctgctg tttttagggg gaatgcaaaa tattccgcaa
     7021 gacgtttatg aggcagccga aattgatggt ttttctaagt ttcagcaatt tcgctatatc
     7081 accatgccat tattaaagcc cacggcgatt tttattttac ttaccacatt gatttcggcc
     7141 tttaaactaa tcattcagcc aatggtaatg actcaaggtg gaccaatgaa ttctactatg
     7201 acaatggttt attacattta ccaaactgga tttacagacc gtatggtagg ctactccagc
     7261 tccattgcgt taatctttac cactatgatt ggtttaatta caattgctca aagaaaattg
     7321 gtaaaggagg atgatccagc atgaccaaga aatttggacc gctaatgatc gtagaatatt
     7381 gtttgctgtt ccttttagcg gcattattca ttttcccgat gctgtggatg gtagtttcct
     7441 ctatgaagcc tgaagcagat gtctatcaaa atttagcttc cttcaaagct tttttaccta
     7501 gtttgaatcc agctaattgg tttaaaactt atcaagaggt tatttcccgg ttcagtgtgg
     7561 gaacttattt attaaacagt attttttatg gtttaacctt tgcctgtggg tcaatcattg
     7621 taaactcttt ggcgggtttt gcctttgcga aggttaattt ttcaggcaag aaaattatct
     7681 ttggagcttt gttagctctg ctgattgtcc cgatggagac ggttttaatt ccgcaattta
     7741 ccatcgttaa ttcactaggc ttagtgaata ctcgcttggc agtgatttta ccagcgatgg
     7801 ccagcgcgtt taatatctat ctgtttagaa atttctttat cgcgattcca gaagaaatca
     7861 ttgaatcagc gaaattagat ggtgcaaata ttgttaaaat tttctttcac atcatgctgc
     7921 caatgtctaa accagccata gccacagtag gtgtcttatc ctttatctcc agctggaatg
     7981 attatatttg gccgttaatg gtcttaactg acagcagcaa attttcaatg caagtggcaa
     8041 ttactacgat caatactaca cagccagttt atatcaatca agtgatggct gttttaacca
     8101 ttgcaacgat tccactgatt attgtttata tcgttgcaca aaaatatatt ctgcagggac
     8161 ttggcggttc tggaacgggt ataaaatagg agtgaatagt gaatgttgca aaaactttta
     8221 aaggccaatg agtttattga gaaaaatgct caaacagtca atcaagaata ccggaataaa
     8281 tttcatttga tggctccgat tggctggatg aatgatccaa atggttttgt ttattatcaa
     8341 gaggagtatc acttgtttta tcaatattat ccttacgaca gcatctgggg accaatgcat
     8401 tggggccatg ctaaaagcaa ggatctaatt cactgggagc atttgccagt agcactggca
     8461 ccaggtgaaa gctatgacaa ggaaggctgt ttttccggca gtgccataga aaaggatggc
     8521 aagctgtatt tgatttatac aggacacaat gttgtggaag ggcaagttcg acaagttcag
     8581 tgtttggcag tttcagaaga tggcattcac tttgaaaaat atgccggaaa tccaatcatc
     8641 gcagaagatc acttagcttc tgttgcaacg accgaagatt tccgcgatcc caaagtgttt
     8701 cagcgaaaag aagactattt tactgtagtc gctactaaaa ctgcagatgc tcgtggacaa
     8761 attgtgatgt tccattccaa agatttacta acttgggagt tttattccgt attgctggag
     8821 ggaactccag aacaaggcat tgtatgggaa tgcccagact tgtttgaact agatggcaaa
     8881 gaagtcttga ttctttctcc tattcaaatg actccacaag gcaatgctta ccaaaatacg
     8941 aactcaactg ttgctttcat cggtactgtc gattggcaaa caggcaaatt tctagtagag
     9001 aattttcatg aaatcgatgg cggtttagat ttttatgcac cccagacctg tgaaaacgaa
     9061 gcaggccaaa gaataatgat tgcttggatg caaatgtggc agcgtaaaat acctacgaat
     9121 gatctgggcc atggttggtc aggttccatg accttgccta gagagctgag ggtggctgat
     9181 aatcaattgt tgcaacggcc agtttcatca atttatcaag taattgatcc gcaggaaagg
     9241 attgaatggg cgaagactga agagaatcgc ttcttactga aggacttagt atatgaccag
     9301 cactatttac gcttggaaat caatttaaaa caggcaacga aactagaact tcactatgcg
     9361 aagggacccg accatacatt actgcttaac tatgatgttg aacgggagtg ctttactgct
     9421 tccagggaac acatgccgta tgatttatca ggagctgaaa aggaagtgtt gaaaaagcgc
     9481 agtgtgacga ttcctttgga aaataattgt ctaaccatcg aaattttccg tgatacttca
     9541 gctattgagc tttttctaaa tgatcgtctg actatgagta caacttttta tgagacagaa
     9601 aaaggacagg attttctttt gctggcagac agtgaagtaa ccttttcatt ggaaagcggc
     9661 ttaattaatc tatagaaggg agagctcagt gatgatttat ggttcaatcg aagcaggcgg
     9721 cacaaaattt gtgtgtgcca ttagcgatga agaaatgacg atcaaggaaa gagtgagctt
     9781 tccgacaacg acacctgagg aaacaatacc tttagtcatt gacttcttca aacaatacca
     9841 agcagattta gcagggattg ggattggctc atttgggcct atcgatatcc atcgcgattc
     9901 cgccacttat gggtacatta cctcgacccc gaaa
//
LOCUS       DAZULR010000073         9833 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.076, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000073 DAZULR010000000
VERSION     DAZULR010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9833)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9833)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9833
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.076"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            511..1074
                     /locus_tag="ACG8ZV_002459"
     CDS             511..1074
                     /locus_tag="ACG8ZV_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997729.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
     gene            complement(1135..1500)
                     /locus_tag="ACG8ZV_002460"
     CDS             complement(1135..1500)
                     /locus_tag="ACG8ZV_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02328 family protein"
                     /protein_id="HFS4997730.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(1576..1821)
                     /locus_tag="ACG8ZV_002461"
     CDS             complement(1576..1821)
                     /locus_tag="ACG8ZV_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFS4997731.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(1891..2145)
                     /locus_tag="ACG8ZV_002462"
     CDS             complement(1891..2145)
                     /locus_tag="ACG8ZV_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997732.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(2309..2632)
                     /locus_tag="ACG8ZV_002463"
     CDS             complement(2309..2632)
                     /locus_tag="ACG8ZV_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997733.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            2819..2892
                     /locus_tag="ACG8ZV_002464"
     tRNA            2819..2892
                     /locus_tag="ACG8ZV_002464"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2853..2855,aa:Ile,seq:cat)
     gene            complement(3277..3774)
                     /locus_tag="ACG8ZV_002465"
     CDS             complement(3277..3774)
                     /locus_tag="ACG8ZV_002465"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase family cysteine hydrolase"
                     /protein_id="HFS4997734.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(3814..4623)
                     /locus_tag="ACG8ZV_002466"
     CDS             complement(3814..4623)
                     /locus_tag="ACG8ZV_002466"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFS4997735.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            4957..5814
                     /locus_tag="ACG8ZV_002467"
     CDS             4957..5814
                     /locus_tag="ACG8ZV_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HFS4997736.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            5807..6709
                     /locus_tag="ACG8ZV_002468"
     CDS             5807..6709
                     /locus_tag="ACG8ZV_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HFS4997737.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            6742..7092
                     /locus_tag="ACG8ZV_002469"
     CDS             6742..7092
                     /locus_tag="ACG8ZV_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFS4997738.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            7141..8064
                     /locus_tag="ACG8ZV_002470"
     CDS             7141..8064
                     /locus_tag="ACG8ZV_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFS4997739.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            8142..9035
                     /locus_tag="ACG8ZV_002471"
     CDS             8142..9035
                     /locus_tag="ACG8ZV_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFS4997740.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            9073..9636
                     /gene="amaP"
                     /locus_tag="ACG8ZV_002472"
     CDS             9073..9636
                     /gene="amaP"
                     /locus_tag="ACG8ZV_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HFS4997741.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            9650..>9833
                     /locus_tag="ACG8ZV_002473"
     CDS             9650..>9833
                     /locus_tag="ACG8ZV_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HFS4997742.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFK"
BASE COUNT         3422 a         1663 c         1849 g         2899 t
ORIGIN      
        1 aattcattgg tcgttgaatg ggctgaatag tagtgtataa aacaattttg tggagcgtga
       61 agcttttatg gtagaggaaa atacgaataa agtgatgttg ataaaaagat tcctatcttg
      121 aatatgaatc gagatgtctt gaaaatgaat gagtttgacc aatcattatc ctatcgaaat
      181 ttacagtttc gttcgattgg tctgtcaatt aatgaaaaag taaaaaagaa tatgttctag
      241 gaagagggcg gcacatctaa atttttaagt aacggacagt tcaaatatca agcattgaaa
      301 gaggctatcc tactgtttga aggaatacga atatataaaa acgacaaaga ggaaaaagta
      361 gttcattaaa tcccttcaag tgatgaaaga atgagatcta ataaaacctg atctttcatc
      421 tgttttttta ataacgtaat aattttttta ttttttgtgc tttcgccgtt attgtagagt
      481 gatttagcat tcttattttt aaaaataact gtgttatata ttaaaaaagg cataatagtt
      541 ataagctttt ttaaagaata tttagaaatt attaattttc gtctgaaaac aaaaaaagaa
      601 agcgttatta ttttagtcta ttttcagggg gggaacctta tgataaaaaa actattttta
      661 ctatcaatat taacgctagc aatggcaggt tgttctgact ctggcttagc aactgaactg
      721 atcacaaaat caactgaagc cacgacagag gagttaaaat gtggaaacga tcacagtgac
      781 tacagaggct taaatcgacg atgcatggga atattaggca gaagcaattg taagcatcga
      841 tgtagtaatc gaagaaggtg tagaagaagc aacagaaaaa tcaaaagaaa gatcaaaaga
      901 agcaatctgt gctgtgcatc gtatacagac gtcgaagatg cggtactttt aaaccacgtc
      961 aggagatgtt catttatgtc tagggaagtt ggcgatgaac caaaactaga gtacgctttt
     1021 agttttgcac gtgaggatga agataaccct aaaacttacg acattttagc ttgatctaag
     1081 atggttaaag ctttttaatg aagtaagagg agatagaagg cttttctagt tatattaggt
     1141 aagataaatt cctttttgct ccaaatttgc taaacattct gctagataaa cttcatcgtg
     1201 ttccggataa atcggcacgt tgcgctctac agtaggtaaa tcaaaaaatg cttcgcatga
     1261 tttgccacga tacataggat ttttccactc tggtgctggg ctgtaaccac gtttttccat
     1321 ttcatccatg acaagctgat gatattggaa taatctataa ggagaatagt gaaaaacata
     1381 atccacagta gcatgtttct ttccccagcc atttcctctt aatgcacagc attcccgatg
     1441 ttgtcctaaa agctgttgac gaggaagctt tgaaatcaat ttttcatgcc ataatcgcat
     1501 agaaatgtct cctttatata tagattgtta accttagacg ttaaatgaaa aaaccagcac
     1561 caaggctgga aaaaatcact tcagtttgct tgctgtttct gagcgaccaa ttaggtaatc
     1621 aacggaaata tcgtaaaagt cagcgatata gattaattca atgatgcttg gaatttcttc
     1681 tccttcttcg tacttacgat atttgaataa aggaatactt aacgcgctag aaacagctac
     1741 ttgagataaa gatcggccag ttcttaagaa attcagacga caacgtaaag tatccagtaa
     1801 aatagcttct tcgatactca tttaatcacc tttcattata gtagaatagt tataatgact
     1861 atagaaagct acacatgcaa tcaatagtac tcaatgtttt ttatttaaac gtatcaaata
     1921 aagaatgacg atcaataaag acaaaaccag tcctgataat tcttctataa aaacactatc
     1981 gggttcaaag tagttgtaat taaaaacttt ccacataaag tagatagccg gaagagtcaa
     2041 aatagctaaa taaaaccgtt ctttgttcca attcataaga taaacaatac ttgcgaccag
     2101 tgcgaccgca ggcacccaaa acaaaactct caccaacgta atcatgtaac ggactcctca
     2161 acgattcata taataaaaga taacatgtta ttgcatacat cacaaatgaa atgctaggaa
     2221 aataaaagaa gaatagatca atgaaaaatg aaaaagcaga acagttttct gctgataagc
     2281 aggaactgtt ccgctgaatg tgtcttatct atcgagaaaa aatcaatgga ttgatatcta
     2341 agtaattcaa tacatataaa aagaggacga tcgcattcac taaaaaggaa agaatgatga
     2401 tcccatagcg aatggaaaca tatttaacaa atacttttgt ttgaatacgg gcatatcttt
     2461 ttcctttata gctgagcatc atgacaagaa gcaaaagggt aatcacacct tgaaaaatca
     2521 ttccaataaa cagaattcct gaggtttgat aatttaattg gagaaaataa gctgctgccg
     2581 caactaaatc gaataaaatc gcaataaatg gcaaaataat cactcctaac attgagaata
     2641 aataaaagaa taacattttt tctaaaataa gcaaataaaa attaaagtaa caaaatagtt
     2701 atgacacaag taaaagaaat aagaataaca atattatttt acttatattt tgaaacttgt
     2761 gagagtttgt cattcgtgct atagttgaaa agtaacaaaa ataaatttta tttatgatgt
     2821 acctttagct cagttggtta gagcagacgg ctcataaccg tccggtcgta ggttcgagtc
     2881 ctacaaggta cataagaggt tgtgaaaaag ctgccctgca tcaagtaata agaacagcca
     2941 agtaaaaaca gcttcttatg tttttacttg gctgttctta ttactgcaga tgcaagcttt
     3001 tgaataccgt ttaaggaaga ggttgtgaaa tcagcgtttt gacctgagta ttagcttaac
     3061 aaacggaaaa atagttcctc atattttgcc gtttgttaag ctaataccga gggtcagctg
     3121 attgaacacc atttaagaaa gaggtcgtga gcctgccgtt tcactctgtg tcataaaaaa
     3181 gccaatctac tttgatagaa aaagcacgta ggactaaaac agttctgcgt gcttttttta
     3241 ttgtgtgtta aatatcgtaa atgaagatag atatttttat gattcgacga tagagacgtt
     3301 gaaatctttc aacagctcta aagcggattc tccgtgtttt ctactggaga ctaacattgg
     3361 atcaacaaaa aagtctgctt caggaaaagc actctgcagg cctatcagat tagagagtac
     3421 acacaagttt gtttcaatcc cgactacttc gatctctttt tgttcttctt tgctttcaaa
     3481 taaagtttcc tggatttcag ctaaagtttc aggtggaatc gtaaagtaat actttttaat
     3541 cactcgttca ttttcttgtg gagaaagaag agggatcaat tgcaaatctt ctcgttcttc
     3601 ttctttgtcc ttcagttcaa ctggtatatc ccgtgtgaag agaatatatt cattattttg
     3661 gcgtgcttta gctaatcttt gagcaatacg ttctgccaat tgatctgact ctggaatata
     3721 aaattcgctg tttggatcaa gaatatgatt ttgcatatca ataataacta acattttctt
     3781 tcctcctaca ttcatatcgt cattttattc tttttaatag aagtttttta aaatataagc
     3841 aacaccagct tcttcattcg tcagtgttac ttggtttgca atttctttta cttgtcgctg
     3901 tgcattcccc atcgcaatac tcaacccgct gtaattcaac atagcaatgt cgttttcttg
     3961 atcgccaaaa gccatgatgt cactcgattc gattccaagg taatccgcca gaaaaacaag
     4021 tgaatgagct ttagtgatac ctgtaggcgt gatttctaag aaatgcggat cagagaatac
     4081 tgattggata ccatctgctt gcagatctct ttgtagcttc tgtagttttt cttcactctt
     4141 atctgttaat gctaatttaa gatagctaag agaaggatct tccaacatat ttaaaatttg
     4201 atcaaaagaa tggttctgta aattgaaatg ttcataataa gggtcatctt tgactagatt
     4261 tgattcatcg aatgtcagct gatcatcttg ggtttctcgg ctagcaatga tggatatttt
     4321 cgcttcttga gcatagaaga aggcttttct cagtgtatcg ctatctattt ttgaacgtct
     4381 gagaactttc gccatttttc catccttcat ttcagcaatc agtgaaccat tggaagaaat
     4441 caaatagcca ccgattccta attcggaaaa aatatcttta gcagaaatgc tgttccttcc
     4501 ggtagcgacg gttacgattc cgccattttc atcaaatttc cgaagtgctt ggatattttc
     4561 ttctggtatc tttccatttc gatcaagcaa ggtaccgtct aaatcaatcg ctgctagttt
     4621 cattttatct tcctactttc tttttacata tctattttcc tgttacctta agattaaatg
     4681 agaatttaaa aaaatgaaac taacttgctt tgtcattatg aattttttca aaaaacattc
     4741 ttaagaaaaa ggtggctata tatagtagtt tttggtcaat acctttgaat aaaaagccat
     4801 gaaaaacgaa tagttagcgc ttaccgatgc gttttgtgat aaaaaaattt taaaatattc
     4861 aatgaaaaca aagcatatat tttgctttaa aaccaaatga ggaatattct agatgtagaa
     4921 caggttagaa aaagattaga aaaaggagtg attttgatgg agaagagata cggcgtagtt
     4981 cctgtggtaa ctgcttcaga cgaaaattat gctccttact tgagcgtgat gatcgcaact
     5041 gcattagaaa attgcaataa aacaagacgc ataaaatttt atgtgattga cgatggtcta
     5101 tcagaatata gtaaagaagg attggaagaa acggtaaata aatattcaag taatgcaagt
     5161 atccaattcc tgacagtgga aaaagatatc tacgaagact tcctagtcag tgaccatatc
     5221 acaactaccg cttacttaag aatttcttta ccaaacttat tagctaaaga ggattataag
     5281 aaagtccttt acttagattc agatgtgtta gtactagacg atatcgtaaa actatatgat
     5341 gagccgttaa atggaaaaac aatcggcgct attatcgatc caggccaagt gaaagctttg
     5401 gaaagattag gaatcgattc cgatgacttg tacttcaatt caggagtgat ggtgattgac
     5461 attgatcaat ggaataaaaa agaaattaca gaaaaaacta tccattacct cagtgaaaat
     5521 ggcgatcgaa tcatctatca cgaccaagat gctttgaatg ctgtacttta tgaagattgg
     5581 gaacaacttc atccaaaatg gaacatgcag acttcgctga tttttgaacg tcatccagca
     5641 ccaaatgaaa aatatgaacg tcagtataaa gaaggaaatg aaaaaccttc gatcgttcac
     5701 tttacaggac atgataaacc ttggaatacg ttgaaagatc atccgtatac caatttatac
     5761 ttaaaaaaat tagcacacag tactctaacg aaagtaggcg agatcaatga ataaaaaaga
     5821 aatagcagta gtcgcaagtt gtaacacaaa attcgtacca catttagctg cattatttgt
     5881 ctcagtatta gataattgca acccgtctaa atttgttcgg ttctatgtga ttgacgatga
     5941 tatcgatttt gaaagtaaac agcttttacg cttctcagtg aaaaacgcac gaatgaactc
     6001 agatgtggaa ttcttgaaaa tcaataaaga attctttaca aatgtggtaa tcagcgatcg
     6061 tattccagaa acagcttatt atcgtattgc gattccggaa ttgttccgcg gcacagaagt
     6121 tgaacgtatc ttatatatgg attgcgacat gatcgcttta caagatatct ctaaattatg
     6181 gcgtcttgac ttcggtgatt caatcgtagc agctgttgaa gacgctgggt tccatcaacg
     6241 actggaaaaa atgaaaattt cagctaaatc aatgcgttat ttcaactcag gtttgatgct
     6301 gatcaatgtg aaaaaatggt tagatgaaaa tattacgcaa aaagtattag atttcatcga
     6361 acataatcca gaaaaattac gattccatga ccaagatgca ttaaatgcta tcttacatga
     6421 ccgttggtta ccacttcatc cgcgttggaa tgcacaaggc tatatcatgg caaaagcaaa
     6481 aaaacatcca acagcagcag gtgaacgtga atacgaagaa actcgcaaca atccttacat
     6541 tatccatttt tcaggacatg tgaaaccgtg gagcaaggat tttgaagggc caacgaagaa
     6601 atattacgaa aaatatgcag ggatgacggc tttccgttgt gtagctaaat tccctaaata
     6661 tccaaaatat gcaaaagttc aaccaaaaac agatgtagtt gttaaataat agaagacaac
     6721 aactgaagag ggggagtagg aatggaaatt acaatgtcta aaaatgcagt agagacgtta
     6781 attgaaaagg ttggggaaaa tacaaaaatc gcactcgcgc ttatcaatga ttccgatcca
     6841 tttctaaggg acaaaggtgc ttttgcaaaa ggcagctttt ttcaaatcat tccttttgtt
     6901 tcggaatttg gagaatatgc gactaaaatc gagcatccat tattggacat ctatacatct
     6961 aaattagagc aaaattattt cggtaaacga ttgaacatgg acttcaacaa acagcttgac
     7021 agcttttcat tagaaaatga aatcgcagta ctcgattata atatcaaatt aaagaactgc
     7081 ttcttcagct aatagtttcg agaaagtcca aaaaggaggt atacattgag atactacttt
     7141 gtggatgaag aaaagaatgt aatagaaaca gatgaaaaaa aatataattg gctcgtactt
     7201 gatagtgcaa agcccgaaga gattgagcaa gcaatcgaag aattcgagct tcctgatgat
     7261 attttcgtag gaaccgaata tccggaagaa gtttctcgga tggagcgcct ttatgagacg
     7321 aaactagagc atccattttc tttggtagtg attaatctag atcagtcaga taatcgtatc
     7381 gaaaaaaaat taacgccaat atcttttgta ctttccgata atctcttgat tacttgtatc
     7441 gatagaaaaa ccgaatttgt ggatcggctg ctgacaaagc atggaaatca tttaaactcg
     7501 tttgaaaaga tcatcacgta tacattatta gatatttaca cccattacgt gaaagaacta
     7561 agagagatga aaaagcgaat tgacgctttg gataaagcag ctcgtaaaac aacggaaaat
     7621 gaagaactgt ataaacaggc agatcttgaa agagacatcg tatatatcga tcatacctta
     7681 agagatcaac gggaaacaat ggatcaatta tggaattctg aaactttcat caaacgttta
     7741 gacgatgaac agctactcta tgatgtccat ttgagacagc gacaaacaga aaaaatgatc
     7801 gagatctatc gagatttatt agagagtatt ggtgatctat tcaacgggat gatggacaat
     7861 aatctaaatc atatcatgaa atatctagat tcagctgcat taatcatttc cgttccggcg
     7921 ttgttcgcag ggatttgggg aatgaataca ggaggattac cgggtaaaag ttctgctcta
     7981 ggctttatac tcgtagtctt tggctctttg atagcagcag tagttttagg ttaccattta
     8041 taccggaaag attatacaaa ttaaagaatc tatttaaaac aggtatcaaa caaagaaatt
     8101 tgttttggca atacaattta aaaactagga ggaatacagc aatgacagaa ccaaaattaa
     8161 tcgacccgcg aaacttgtac catacggaga aatttcctaa acaagatcag gatacaccag
     8221 ctttacagca gaatatgatt cctgttcctg attgtggaga agaatcctat gaaggcaata
     8281 atcaactaga aaaccgccgt gtactaatca ctggtggaga ttcagggatc ggtcgtgcag
     8341 cagcgattgc atttgctaga gaaggggcag atatcgctct tcaattcttc ccaggagaag
     8401 aaaaagatgc agaggaagta gcaaaatacg tgaaagatgc aggacgtaag attgtcttac
     8461 taccttttga tcttcgtgac gaacaagcac ctaaagaaat catagataaa gccgtgagtg
     8521 aacttggcgg gctagatacg atggtactaa acgcaggaca gcaaatttct tgtcagtcta
     8581 ttgctgagtt accacttgag caagtcaaag acacatttat gataaacatc atcgctatgt
     8641 ttgctttagt gaaagaagct gttccgcata tcccagcagg aggagcaatc gtaacaacaa
     8701 cttctgttca agcattcaat ccaagcgaac atttattaga ttacgcagca acaaaagctt
     8761 caatcgctaa ctttacgatc ggtttagcaa aacagcttgc acctaaagga atccgtgtaa
     8821 atggtgtagc acctggtcca atctggacac cattacaact agacgaagga caaccttctg
     8881 attcgatccc tgaatttggt cagcaaagtt tactagaacg tgcaggtcag ccaggagaat
     8941 tagcaccagt ttatgttttc ttagcatcga ataaagcaag ttatgttaca gcccaaattt
     9001 acggagtaac tggtggagaa gcgatcaact tataagaagt tgatcgtttc acccctatga
     9061 ggaggtgcga aaatgaataa aggtgtaaaa acgatcggag tgatcggaac attacttttg
     9121 ctatctgtgc ttttgtttgc gatactatta agtgcaacct atccattgcc ttttcagcta
     9181 gagaagtttc gattcttttc catcactaat tcatacgtgc aacaatatgt attttggctt
     9241 gccgttgcat ttgctatttt gacaattatc acgttacttg ttttcctgtt ttatccaaaa
     9301 acaatcggaa actttctact gaaacatggt gatggggagt tgacgttgga taaaaaagca
     9361 attgaaggaa tggttcgttc tcacttgcat gaagatgaat tcatccattc accaaaagta
     9421 aatgtcaaag caacgaaaaa caagatcgcc gtcaatgtaa aaggggagtt gaaacgaact
     9481 tcagcactca ttggtaaaac aggaacattg atgaaagaaa tcgaaaatga agtacaacac
     9541 atattgggaa caaaagagcc agtgaaagta tcggtgaaat acacaggctt tgaagaacca
     9601 gctaaacgaa gcaatgaccg caaacgagta gaataggggg ggaccaaaaa tgaaagaact
     9661 attttcgaca tacaagctcc ctatcatctt tggggtactt ggattgatat tagccgtttt
     9721 atggatcacc gtgggctttt tcaagacctt attgatcttg atcatggcag cgatcggcgt
     9781 cgctatcggt ttttatctga aacaaacgaa aatcttagat cactatttta aat
//
LOCUS       DAZULR010000074         9727 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.077, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000074 DAZULR010000000
VERSION     DAZULR010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9727)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9727)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9727
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.077"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            54..746
                     /locus_tag="ACG8ZV_002474"
     CDS             54..746
                     /locus_tag="ACG8ZV_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFS4997743.1"
                     /translation="MRKKIIINAGVIIGLMLVIFSGKQYADNILLWGGEDNIEKINNN
                     LTILDTALENKEQKISILNSQLSSNNQTLEQLRTNIEVSKQKVASLENDKNQLVSEKT
                     NLENQLSAKDSELQGKQNEINAKIDEINQKVAEINRLNSDWNNRLQNEKNKFNEEQST
                     INSLNQQINQMLSEKNNIQNQLQATQQKLEEEKSKNSSLNNYIEKLQKAKNDVEDTAN
                     KAQQIVNEHTIQ"
     gene            1174..1566
                     /locus_tag="ACG8ZV_002475"
     CDS             1174..1566
                     /locus_tag="ACG8ZV_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997744.1"
                     /translation="MLDDRLTCSNCGTLFYYEEVRNIVKHRKKEMPIRCPNCNEVIKR
                     KLSHGYFVSYELYEESKINLKKKPKYYKNLKTGAIITEKEFKNLVTEEESRFYNLSGN
                     ICPGFMDQIIENESIESIENYVPVDLPK"
     gene            complement(1739..1942)
                     /locus_tag="ACG8ZV_002476"
                     /pseudo
     CDS             complement(1739..1942)
                     /locus_tag="ACG8ZV_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            1938..2105
                     /locus_tag="ACG8ZV_002477"
     CDS             1938..2105
                     /locus_tag="ACG8ZV_002477"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997745.1"
                     /translation="MENTFELYNKTTVDKLIPILVPTDLNGHDVLLRFNGFLGEDYRY
                     LKISDPQPLTE"
     gene            complement(2148..2723)
                     /locus_tag="ACG8ZV_002478"
     CDS             complement(2148..2723)
                     /locus_tag="ACG8ZV_002478"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HFS4997746.1"
                     /translation="MAQLFYRYGTMNSGKSIELLKVAHNYEEQGKRVIIMTSAIDTRS
                     GFGKVESRIGVSKPAIAITSEMDVYGELVEIIDQYGKVDCILVDESQFLSRENIIDLS
                     LIVMNEEVPVICYGLKNDFQNNLFKGSEALLTFADKIEEIKTICHFCNKKAVMNARIV
                     DGIPVYSGEQIVVGGNEDYLSVCRNHYYNED"
     gene            complement(2878..3404)
                     /locus_tag="ACG8ZV_002479"
                     /pseudo
     CDS             complement(2878..3404)
                     /locus_tag="ACG8ZV_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            3861..5372
                     /gene="gadC"
                     /locus_tag="ACG8ZV_002480"
     CDS             3861..5372
                     /gene="gadC"
                     /locus_tag="ACG8ZV_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015082498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate:gamma-aminobutyrate antiporter"
                     /protein_id="HFS4997747.1"
                     /translation="MNKKKLSLFGFFALTASMVLTVYEYPTFATSQLHLVFFLLLGGI
                     LWFLPVALCAAEMATVEGWKDGGIFSWVSQTLGERFGFAAIFFQWFQITVGFITMIYF
                     ILGALSYVINFPELNTDPFIKFIGVLVIFWVLTFSQLGGTNRTAKIAKAGFVIGIVIP
                     SIILFGLAAAYFIGGNPIQMAINAKAFIPDFSQLSTLVVFVSFILAYMGVEASASHIN
                     ELENPQRNYPLAMFLLVILAIALDAIGGFSVAAVIPQHDLSLSAGVIQTFETLILHFN
                     SHLHWLVKVIALMIACGVMGEVSSWVVGPSRGMFAAAQRGLLPVFFRKTNKQDVPVPL
                     IMIQGIIVTIWAAVLTFGGGGNNLSFLVAISLTVVIYLVGYLLFFLGYFVLVFKKKDL
                     KRTYNVPGKTVGKTIIGGIGFILSVFALLISFVPPASIAASEHRTYQIILLISFVVTV
                     LLPFIIYEVHDKSAHTTIEEPTHVKAEDVNPAVYPAARGEHHVTKNDEHILKH"
     gene            5385..6785
                     /locus_tag="ACG8ZV_002481"
     CDS             5385..6785
                     /locus_tag="ACG8ZV_002481"
                     /EC_number="4.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004351 - glutamate decarboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0006540 - glutamate decarboxylation to
                     succinate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate decarboxylase"
                     /protein_id="HFS4997748.1"
                     /translation="MLYGKDNQEEKNYLEPIFGSASEDVDLPKYKLNKESIEPRIAYQ
                     LVQDEMLDEGNARLNLATFCQTYMEPEAVKLMTQTLEKNAIDKSEYPRTTEIENRCVN
                     MIADLWHAPNNEKFMGTSTIGSSEACMLGGMAMKFAWRKRAEKLGLDIQAKKPNLVIS
                     SGYQVCWEKFCVYWDVELREVPMDEKHMSINLDTVMDYVDEYTIGIVGIMGITYTGRY
                     DDIKGLNDLVEAHNKQTDYKVYIHVDAASGGFYAPFTEPDLVWDFQLKNVISINSSGH
                     KYGLVYPGVGWVLWRDQQYLPEELVFKVSYLGGEMPTMAINFSHSAAQLIGQYYNFVR
                     YGFDGYRDIHQRTHDVAVYLAKEIEKTGIFEIINDGSELPVVCYKLKEDPNREWTLYD
                     LSDRLLMKGWQVPAYPLPKDLDQLIIQRLVVRADFGMNMAGDYVQDMNQAIEELNKAH
                     IVYHKKQDVKTYGFTH"
     gene            complement(6950..8385)
                     /locus_tag="ACG8ZV_002482"
                     /pseudo
     CDS             complement(6950..8385)
                     /locus_tag="ACG8ZV_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328084.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            8778..9371
                     /locus_tag="ACG8ZV_002483"
     CDS             8778..9371
                     /locus_tag="ACG8ZV_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA];
                     GO_process: GO:0043170 - macromolecule metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043412 - macromolecule modification
                     [Evidence IEA];
                     GO_process: GO:0044238 - primary metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IbrB-like domain-containing protein"
                     /protein_id="HFS4997749.1"
                     /translation="MNKDITFPVMDVRLVPITKIQANDYNPNRVASPEMNLLELSIIE
                     DGFTQPLVCYYKEKEEKYILVDVLHRYRVAKERLNLKVVPVTVIDKPIEERMASTIRH
                     NRARGTHEIRGMEIVIQRLVKNGWSDKRISKELGMDIEEIFRFKQVSGGMATVFLTNF
                     IRCRTSFRMLFRLSLTMSLLGCDDLRQELTVKVRLPR"
     gene            complement(9355..>9727)
                     /locus_tag="ACG8ZV_002484"
     CDS             complement(9355..>9727)
                     /locus_tag="ACG8ZV_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFS4997750.1"
                     /translation="IKQPLTEVEIFHTDRGKEFDNQAIDELLTTFDINRSLSHKGCPF
                     DNAVAESTYKSLKVEFVYQYTFETLQQLDLELFDYVNWWNHLRLHGTLGYETPVGYRN
                     QRLAQRILDNELGCANASEAV"
BASE COUNT         3221 a         1562 c         1719 g         3225 t
ORIGIN      
        1 aaaataattt ttaataactt atttaaggaa attttttgaa ggagaagata aaagtgagaa
       61 aaaagattat tattaatgct ggagtaatta taggattgat gttagtaatt ttctccggaa
      121 agcaatatgc tgataatatt ttattatggg gaggggaaga taatattgaa aagatcaaca
      181 acaatttaac tatattagac acagctctag aaaataaaga gcaaaaaatt agtattttaa
      241 attcacaatt gtcttcaaac aaccaaactc ttgaacaact aagaactaat attgaagttt
      301 ccaaacaaaa agtggcatct ttagaaaacg acaagaatca attagtatca gagaaaacta
      361 atttagaaaa tcaattgtca gcaaaagact ctgaattgca aggaaaacaa aatgaaatta
      421 atgcgaaaat agacgaaatt aaccaaaaag tagctgaaat aaatcgatta aatagcgatt
      481 ggaataatcg tttacaaaat gaaaagaaca aatttaatga agaacaatct actattaata
      541 gtttaaacca gcaaattaat caaatgttga gtgaaaaaaa taacattcaa aatcaactgc
      601 aagctactca gcaaaagcta gaagaagaaa agtcaaaaaa tagtagtttg aataattaca
      661 ttgaaaagct tcaaaaagct aaaaatgatg tagaggatac cgcaaataaa gcacaacaaa
      721 ttgtaaatga acatacaatc caatagatat agttttaatt taacaaatgg tatgtttgga
      781 gataatgaga tagaatataa atgtcataat attatacaat ctaaacaccg tttccttttc
      841 tatttttgat gacatcagta tatagctact cgaaagagta gtctttttat tattctcgct
      901 tattattgat atgaaaattt cgatttgaca aaaggtaccg aataattttg taatatgaat
      961 tattatcaag aagtaattat gatgataaca tatggaaact agttagtaat aataacaggt
     1021 gattaaactt ttgaacgact tgtaattcta tattttttct tttaagtaaa aaatataggt
     1081 gatttttttt gacttcatat ttataataaa gacacgtaaa tcaattattt ttcattttac
     1141 tttaactaat aatgtttatt tggagggatt attatgttag atgatagatt gacgtgttct
     1201 aattgtggta cattatttta ctatgaggaa gttagaaata ttgtaaaaca tagaaaaaaa
     1261 gaaatgccta tacgttgtcc aaattgcaat gaagttatta agcgaaagtt gtctcatggt
     1321 tattttgtca gctacgaact atatgaagaa agtaaaataa atctgaaaaa aaaaccaaaa
     1381 tactataaaa atttgaaaac tggagctatt ataactgaaa aagaatttaa aaatttagtg
     1441 actgaagaag aaagcaggtt ttataatttg tctggtaata tttgccctgg atttatggat
     1501 cagattattg aaaatgagtc aattgaatca attgaaaact atgttcctgt tgacttacca
     1561 aaatagaaaa aataatcctg tttttacagt gaattatttt aattttgatt ttcaataaaa
     1621 atatattaca ataataatcg taatagctaa tgaaacaatt tctcaatctt tttaccactc
     1681 caaacaggga gcgtcaataa ttttgtgtaa ataactcgtc cttctgcaaa ataatgggtt
     1741 actcagtaaa cattgaagct aatgtatccg tcacttgttg gaagccttta tggcttctat
     1801 ttaagaattt ttgattgtat gtatcaaaga tggatactag gaaacgctct agtgattctt
     1861 cattttgaaa ctgctctttt ctgcggctgt atttcttgat ttgtttattg aaagattcga
     1921 ttgtagaacc agaaggaatg gagaacactt ttgaacttta caacaaaact actgttgata
     1981 aattaattcc aattttagtt ccaactgatt taaatggtca tgatgtttta cttcgtttta
     2041 acggattttt aggtgaggat tatagatacc taaaaatttc tgatcctcaa cctttaacag
     2101 aataataaaa aacgtgtaat caattatttg attacacgtt ttttatttca atcttcgttg
     2161 tagtagtggt tgcgacatac cgaaaggtaa tcttcattac ctcctactac aatctgttca
     2221 cctgaataaa ctggaatacc atcaacaata cgagcattca ttacagcctt tttattgcaa
     2281 aaatggcaaa tagttttaat ttcctcaatt ttatcagcaa atgtcaataa tgcttcggat
     2341 cccttgaaga gattattttg aaaatcattc ttcaatccat agcaaattac tggtacttcc
     2401 tcattcatta cgataagtga tagatcaata atattctctc tacttaaaaa ttgagactca
     2461 tcgaccaaaa tacaatcaac ttttccgtac tgatcaataa tctccactaa ttctccgtac
     2521 acatccattt cagaagtaat tgcaatagct ggtttcgaaa cacctatacg actctcaact
     2581 tttccaaatc ctgatcgagt atctattgcg cttgtcatta tgataactct cttcccttgt
     2641 tcttcataat tatgagccac tttcagtagc tcaatactct ttccactatt cattgttcca
     2701 tatctgtaaa ataattgtgc cattaaattt attcccttct tttacaattc aattattcct
     2761 taattccatc tgcttttatg cagctgctcg tttattcctt gatatgtcta taacatctac
     2821 tatccctaaa accaatttat aagccattag agatggtatt cctgaacatc tctcatattg
     2881 ttttttgagt ggtatatcat ctgaaaaact gaaggaatca tgaaaatagc gacatactta
     2941 tcatttagag ttctaacttt aaatgcattt acttcttcag tcagcacttt agtcatgttg
     3001 gacatggttt ggggcgtgta gtgatgccca tacattttct caatcaagtc tgcgatttcc
     3061 gacatggtaa taccttttcg gaagaggtga atgacggtct cctctaatgt gtcattcgtc
     3121 cgtctataag caggaacagt ctgttgcttg aactcgccat tgcggtcgcg cggaatctgg
     3181 agatgaagtt ccccatactc ggtcttgacc gtacggtcat aggagccgtt acgagaatta
     3241 cccgtgttaa aaccaatgcg atcgtacttt tcgtaatcga ggaaagccgt taactccgtt
     3301 ttgagaagcg tattgacagc tttttccaaa tggacacgga ataatccatt caaatcgcct
     3361 ttgttcgcta gagtctttag gatttctgta gtaaaatcgt tcatatggaa gtcctctttt
     3421 ctgtgaatgt gttgtggtaa ctctattcta cagaagggac ttcctttttt ctatttacac
     3481 aaaatatttt acactctcaa caaaagtatc ttcgattaat acttgctcaa gttatgtgca
     3541 gctacgaaaa agtaggtacc gaggtacttt ctttttcgca gctttttttg gacttatgag
     3601 aagtacattc gctggaagaa tacgatataa aacgagcttt ttcactaaag atattaatag
     3661 agtgaaagaa acaagctttt gttgtcagtt ttttcacttt tctaaaaatg aaaataaaaa
     3721 attctggaag tggagaagaa ttttgcttgc tatactttgt cttgtagaaa agaggtagac
     3781 aaaataatgc aagctcaaat aagcgatttt ccataacctt ggtaggaatg acaaattaaa
     3841 taggaaaggg aagtaataat atgaataaaa aaaagttatc tctattcggt ttttttgccc
     3901 tgacagcttc catggttttg actgtttatg agtatccgac ctttgcaaca tcacaattac
     3961 atttggtttt ctttcttctt ttgggaggta ttttatggtt tctaccagtt gctttatgtg
     4021 ctgcagaaat ggcaacagtt gaaggatgga aagatggtgg gattttcagt tgggttagtc
     4081 aaactttagg agaacgtttt ggttttgcag ctattttttt ccaatggttt caaattacag
     4141 taggttttat tacaatgatc tacttcatac taggagcgct gtcgtatgta attaattttc
     4201 cagagcttaa tacagatcca tttatcaagt ttattggtgt attagtcatt ttctgggtac
     4261 tgactttttc acagttgggc gggaccaatc gtaccgctaa aattgctaaa gcaggatttg
     4321 tcattggaat tgttattcct tcgatcattc tctttggttt agcagcagcc tactttatcg
     4381 gcggtaatcc gattcaaatg gctattaatg cgaaagcttt tattcctgac ttttctcagc
     4441 tttcaacttt agtagtattt gtatctttta tattggctta tatgggcgta gaagcttcag
     4501 catcacatat taatgagctg gaaaatcccc aaagaaacta cccattggca atgtttttac
     4561 tagtgatttt ggccatcgcc ttagatgcaa tcggcggttt ctcagtagca gcggttattc
     4621 cacaacatga cttgtctctc agtgctggtg taatccaaac atttgaaacg cttattttac
     4681 attttaacag tcatttacat tggttggtaa aagtgattgc tctcatgatt gcctgtggcg
     4741 ttatgggtga agttagttct tgggtagttg gtccatcacg agggatgttt gcagctgctc
     4801 agcgaggtct gttaccagtt ttcttccgga aaactaataa acaagacgtt ccagttccgt
     4861 tgattatgat acaaggaatt atcgttacta tttgggcagc agtcttaact tttggtggag
     4921 gaggcaacaa tttatcattc ttagtagcaa tctccttaac tgttgtcatt tatctcgtag
     4981 gatatttact atttttccta ggttactttg tattagtttt taagaaaaaa gacttaaaac
     5041 gaacttacaa tgtaccagga aaaactgttg gcaaaacgat tatcggtgga attggtttta
     5101 ttttatcagt gttcgcattg cttatctctt ttgtaccacc agcttcaatt gcagctagtg
     5161 agcaccgaac ataccaaatc atactactta ttagctttgt agtgactgtt cttttacctt
     5221 ttatcattta tgaagtacat gataaaagtg ctcacacaac tattgaggaa cctactcacg
     5281 tgaaagctga agacgttaat cccgctgttt atccagctgc tagaggagag caccacgtta
     5341 caaaaaatga tgaacatatt ttaaaacatt aggaggaatt cattatgtta tacggaaaag
     5401 ataatcaaga agaaaaaaac tatttggaac caatttttgg ctctgcaagt gaggatgttg
     5461 acttgcctaa atataagtta aacaaagaat ccattgaacc acgaattgct tatcaattag
     5521 tacaagacga gatgttggat gaaggaaatg cgcgattaaa cttagctact ttttgtcaaa
     5581 cgtatatgga acctgaagca gtgaaattga tgacccaaac gttagaaaaa aatgcaattg
     5641 ataaatcaga atacccacga acaacggaaa ttgaaaaccg ctgtgtaaat atgattgctg
     5701 atttatggca tgctccaaat aatgaaaaat tcatgggaac ttcaacgatc ggctcttcag
     5761 aagcctgcat gctgggtggt atggccatga aatttgcttg gcgtaaacgt gctgaaaaat
     5821 taggtcttga tattcaagca aaaaaaccta acctggtgat ctcttctggt taccaagttt
     5881 gttgggaaaa attctgtgta tattgggatg tggaactgag agaagtccca atggatgaaa
     5941 aacatatgtc aattaatcta gatactgtca tggattatgt ggatgagtac acaattggta
     6001 ttgtaggtat tatgggtatt acttacactg gtcgttatga tgatatcaag ggtctgaatg
     6061 atttagttga agctcacaat aaacaaactg actataaagt atacattcat gttgacgctg
     6121 catcgggtgg cttttatgca ccatttactg aacctgatct agtttgggat tttcaattga
     6181 aaaatgttat ctcaattaat tcttcaggtc acaaatatgg tttggtatat ccaggtgtgg
     6241 gttgggtctt atggcgtgac caacaatact taccagaaga attagtattt aaagttagtt
     6301 acttaggtgg agaaatgcca actatggcta tcaacttctc tcatagtgca gcacaactaa
     6361 ttgggcaata ctacaacttt gtacgctatg gctttgatgg ttatcgtgat attcaccaaa
     6421 gaactcatga tgttgctgtt tatttagcca aagagatcga aaaaactggt atttttgaaa
     6481 tcattaatga tggatcagaa ttgccagttg tgtgctataa gctgaaagaa gatcccaatc
     6541 gcgaatggac actatatgat ttatctgatc gtctgttaat gaagggatgg caagtcccag
     6601 cctacccatt acctaaagac ttggatcaat taattattca acgcttagtt gttcgagcag
     6661 actttggaat gaacatggct ggtgattatg tacaagatat gaaccaagca attgaagagt
     6721 tgaataaagc tcatattgtt tatcataaaa aacaggatgt gaaaacgtac ggctttactc
     6781 actaaaattc ttcagagaaa tataaaagaa gttaattaac taataaaagg agttgtgatt
     6841 accacacagc tccttaaatc tatttgaata aatatatgat attcatttgt tacactctca
     6901 atcttagctg ttgttctatt catcattact cttattgtaa gtagttcagt caaatttgct
     6961 tgttcaattg atcgataaca gtatgaattg tttgaaaagt aatcggatat ataattgttt
     7021 tctcactacc taagccttct tggtataaag aactatcgca aagtataatc cgctgagtac
     7081 aaaagaaagt gtcgtctact atttctctaa gttgtttaca aatgatatta ctaatagaaa
     7141 agtgttctcc caaaatgtct tctaactgtt gtcgatagta taaataccta aagtctgacg
     7201 gagctactat gaacacttca attggagatt tccgtttatg ctcatttaaa agacttaaac
     7261 taatggttag tttacgaata gaattctcat tccaacgcag aaataaattg ttttgttttc
     7321 gccattgttc aagaatttca tgaacttcta agtacaaagc gcgttgctct tcatttaaca
     7381 agtaagtctt atcaggttga aatatctgaa tatcagccca aagtgagcgg ataaacggga
     7441 gaagtgcttt atcaaaaagt atctgatttt cttcagatat attcagagat aagataagtt
     7501 tttgactgag ctcaatcacc aaagggttat ctgctacatg gttttgataa acaacgttca
     7561 agtctttttg taacaattca aagttatcgc atagataatt tctagagttg aatagaaagt
     7621 agatataaag gcattcatct tcgtcatgac ataaagagaa agaaagttgc tctaatcctt
     7681 tctgtattag ctgaaacaag ggagtatgtc gggcaactct tttttcttcc tgactaaaat
     7741 atattgggtt agtcttagat ctctgcaaac cgatagcgat acctaataaa ataaattgtt
     7801 tttcaactgt agggtaactt cttgaaaaaa atgtttttct acataatcaa tcaattgttg
     7861 accgctttga ataattgatt tatttagctg gatcaactct gtccgatttg tctcatagat
     7921 tatcgttagt aacaaacttc gataatcctt ttcaggaatt tcaaaatggc catcagcatt
     7981 taagtactgc atttgtttaa aaaaattaat caactcattt cgtaagttgt aaactttgct
     8041 taacgaaatg aaggtagtat cagctatatt actccaattg tgttcccctg ataaataatg
     8101 tcctagtaca ttgaaaaagt cagagcgctg atagatgagt tgagtgagtg ccaacctcga
     8161 aaacgaagag tcgaatgcga ctgtaaagct acttctagat ttctccactg aaataatttg
     8221 ctgatggagt atgtcggtaa tgcattccaa gtcgttagtg acagtgagtg ggcaaacgtt
     8281 caattgatct gctatttcgc gaatctgaat ggtccctttt tcgtgtaatt gctcacaaat
     8341 gtaaacttga cgaaaaatac ttttctccag ataggtttcc aacatagtac tcctcctagt
     8401 cattttatac ataactatta taactctacc aatcggaata gtcctgtaat atattgaatc
     8461 aaaaatataa attataaaat aattagatgg ggtatttggt ttaagtatcc cttatatagt
     8521 aataaattta taggtgtgat tctcgaatta atacccgaaa atgtgagaga atttttatgg
     8581 attttttagg atacaaatta attatttttg cttttatcct gattaccagt ccagtactgt
     8641 cggtatccca ttttgcagca aaatcatgtt gataaagtga caagaagact gatgagatat
     8701 attatccaaa ttgagaagat aattaatcgg attcttgagt ataccctact ttttaagaaa
     8761 gtagggtata caagcgtatg aataaagaca taactttccc tgtgatggac gttcggcttg
     8821 ttccaattac caaaatacag gcgaacgatt ataatcccaa tcgagtagcg tctccggaaa
     8881 tgaacttatt ggagctttct atcattgaag atggctttac tcaaccatta gtttgttatt
     8941 acaaggaaaa agaagagaag tatatcttgg ttgatgtgct tcataggtat cgtgttgcta
     9001 aggaaagact caacttaaaa gttgtaccgg taacagttat tgataaaccc atagaagaac
     9061 gtatggcttc aacaattcga cacaatcgtg caagagggac ccatgaaata agaggaatgg
     9121 aaattgtcat ccaaagatta gtaaaaaatg gatggtcaga caagagaata tccaaagaat
     9181 taggcatgga cattgaagaa atttttcgct ttaagcaagt gtctggtgga atggcaacag
     9241 tttttttgac aaattttata aggtgcagaa cttctttccg tatgctattc cgattgtcct
     9301 tgacaatgag cctcctcgga tgtgacgatc ttcggcagga gctaacagtt aaagttagac
     9361 tgcctcgcta gcgttagcac atccgagctc attatcaagg attcgctgcg ccaatctctg
     9421 gttacggtaa ccaaccggtg tctcgtagcc aagtgtaccg tgcaaccgaa ggtggttcca
     9481 ccaatttaca tagtcaaata actccaaatc caattgttgt aaggtttcaa atgtgtattg
     9541 atagacaaat tctactttca acgacttata agttgattca gctacggcat tatcaaaagg
     9601 acagccttta tgactcaatg atcgattgat gtcaaaagtt gttaataatt catcaatagc
     9661 ttggttatca aactcttttc cacgatcagt atgaaaaatc tcaacctctg tcagaggttg
     9721 tttgata
//
LOCUS       DAZULR010000075         9286 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.078, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000075 DAZULR010000000
VERSION     DAZULR010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9286
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.078"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(746..1699)
                     /gene="menA"
                     /locus_tag="ACG8ZV_002485"
     CDS             complement(746..1699)
                     /gene="menA"
                     /locus_tag="ACG8ZV_002485"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HFS4997751.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(1712..2815)
                     /locus_tag="ACG8ZV_002486"
     CDS             complement(1712..2815)
                     /locus_tag="ACG8ZV_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HFS4997752.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            complement(2905..3840)
                     /gene="pplA"
                     /locus_tag="ACG8ZV_002487"
     CDS             complement(2905..3840)
                     /gene="pplA"
                     /locus_tag="ACG8ZV_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular electron transfer flavoprotein
                     PplA"
                     /protein_id="HFS4997753.1"
                     /translation="MKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSESSTAQSST
                     AKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKYDNVNENG
                     ESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSSESFQNYA
                     QQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGKVTESNFD
                     YIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPANVEVVTGA
                     THSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            4142..6076
                     /locus_tag="ACG8ZV_002488"
     CDS             4142..6076
                     /locus_tag="ACG8ZV_002488"
                     /EC_number="1.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFS4997754.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            6533..6949
                     /locus_tag="ACG8ZV_002489"
     CDS             6533..6949
                     /locus_tag="ACG8ZV_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HFS4997755.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            6963..7529
                     /locus_tag="ACG8ZV_002490"
     CDS             6963..7529
                     /locus_tag="ACG8ZV_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HFS4997756.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKRDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            7552..8538
                     /locus_tag="ACG8ZV_002491"
     CDS             7552..8538
                     /locus_tag="ACG8ZV_002491"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HFS4997757.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(8693..>9286)
                     /gene="scm"
                     /locus_tag="ACG8ZV_002492"
     CDS             complement(8693..>9286)
                     /gene="scm"
                     /locus_tag="ACG8ZV_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HFS4997758.1"
                     /translation="DSTDTSASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTS
                     ASSDSTDTSTTTSDSTDTSASSDSTDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSS
                     TTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKR
                     ALPKTGSQSNNWITLAGVILLVIGLRITFMSYKKSKR"
BASE COUNT         2758 a         1764 c         1877 g         2887 t
ORIGIN      
        1 attttctggt tttttgtttt ttagttattt atgtaagatt gcttcgataa ttctcaaaac
       61 gaaataagta gggaagttgg agattttgat tatcttcgta actgacgaag agtaaatgaa
      121 tccatttggt atgcactctt aagttcaaaa tattggtatc gatgtttaaa agaaatagaa
      181 atgtatcgaa gaacagatgt ttaaaaaagt gtgactttgt ataaataaat tagaagaagc
      241 aaacgaggat gttaaaagaa taccatatag ttaccaaacc aagaaagttc tcgtcaagtt
      301 cgctggtacg aatcaaatca agtgaaaaaa gggactgtga aaaaaattgt gtcatagtta
      361 gtcacttttt ccgaacaaat agtgttcaat cagctgtcct tcggtattag ctcaaaaaac
      421 ggcaaaatat gaggaactat ttttccattt gtttctctaa tactcaggac aaaacactga
      481 ttttacaacc tctgataaac ggtgttcaaa agccagtttc tcggtattaa gccaaattta
      541 tgcaaaaatg tggaaagcca ttttcacaaa atttttctta atactcgaaa ctaagcgact
      601 ttttcacaac ctcctgataa acggtgttca aaagcttgca tctgcggtaa taagcccaac
      661 caaacgaaaa atataaggag ctatttttat ttggctgttc ttattacttg atgcagggca
      721 gttttttcac aacctcttca tgctgttaaa tggcttgcat aatgattgtt agtaatagcc
      781 ccaatacata actggcattg aataagacca tatttttgat ggaatagctg aaactgatag
      841 gctggggtaa cgtttgcttg aattgatcca aatgcttctt cacaattggc aaggtcaaga
      901 aggtgaccaa gatcggccat tcatagatac cgctcaacaa ccccattaaa atcacgaaat
      961 agcaagcata catcaatagc tggaataaga ctgttcccgc aggacgtccg atataaaaaa
     1021 ctagtgtata gcgatgattt tcaatatcac ggtcaagatc ccgcaaatta ttagccaaca
     1081 tgatattggc aatcgtaaac accaagggta aggaagctaa tacgattgct gctatagccc
     1141 aaagatttcc taccaaagca aattgtccag atgaaaagtt gactgtcaga tcatagacat
     1201 ctgaaccgaa tgtattgaca taaacgacca tggcaaaaat tccaaggccc atagtcaccc
     1261 cactgaaaat ttcccctaaa ggcattcgag ataaaggaat cggtccgaat gtatagaata
     1321 ctccaataaa acaacagata aatcccatca aaagtaaaag ccaacccgta ttgatcgtta
     1381 gaataacgcc gataacaaaa acaaatgcaa tcatagctaa aatcatgttt cgaatcaata
     1441 caggagatag atttctgcgg ccaatgacat tttcttcata cttatatact tcagaatgag
     1501 ccttttcata atccatgtaa ttattgatag cggtagtcgc taaatcaaaa actagcattc
     1561 caataaaaaa taaaaaagtg tttagccaat gtatctcatg aaaaaaagcg atagagaata
     1621 atacccctac cgcaaaagga aatacactag ccacctttgt tcgtatttca actacttcta
     1681 aaaagatttt tagtgtcatg gttcgtactc cttattttag ttcagaacgg tcacccatcg
     1741 tgtaatggga gtcctccgat aatttgaagg tgtctttgat tggatcggtc acatatactt
     1801 tatcgtcttt tgtcacgaag atcgcttccg tcccgttatt caattcgctt tcgacgtatt
     1861 ccagtccttt tttcacaccc attgaaaaga ctgctgtaga caacccgtca ccatcaattg
     1921 atttatctgt tatgatcgtg acacttgcga tatcattgtc gaacggataa cccgtttttg
     1981 gatcaaacaa atgatggtat tttttgccat ctacttctaa ataacgctcg taaattccag
     2041 aggtaactaa tgttttgttc cgttctttaa tagaacctaa aacagatccg cgagccatgt
     2101 tcggatcttg gatgccgact gtccagtctt ggttttcgcc tcttgggctg tggcctaaga
     2161 catagacatt accgcccaag tcaacgatgg cagtggtcac tccttgtttt ttcaagactt
     2221 tcactacttc gtccgtaatg taacctttgg cgattgcacc taaatcgatg atcattcctt
     2281 tttcttttag ataaacagtt ttttctttgt catttagttc gatcttatga taatccacta
     2341 atttcaatgc ctgatcgatt tcttcttggg aaggttttct ggcgtcatca aaaccgattc
     2401 gccataattg tgtgattgca ccaatcgcca tatcgaatcc gccttgagaa tcttggctat
     2461 attcgtaggc ccgcttgact aacgtgtaga cgtcatcaga aacttttact ggtttgatcc
     2521 cagcttgctc attcacttca tcgatctcag aacctttttg attgatcgtg attttatcac
     2581 caagttcttt tactcgatcg aaggcaggtt tcaatgctga ttctttgcct tcatcataca
     2641 cacggatacg aacgtaagtc cctaacaaga actgttcatc agaatatgga tctttcaata
     2701 tcttggtagc tgctgaactt tcagtggttg ttttatttgc tgagttgctg cagccagtta
     2761 gcaccataaa agagatgccc agtgtgatta aggaaaatag tagttttttc cgcatctttt
     2821 tcctctcttc attttgaaag gtgagacgac tgcctaatct ggctatcgtc ccaccctcca
     2881 acttttatta gtatgattat gtgattattt ttctgttacg atattatcta cttcgattgt
     2941 ttgagtgtcg cctttttcag ctgcattcac taattgttgt gcgtacatga tgaatgaatg
     3001 tgagctgtgt gtagcacctg taacaacttc tacattagca ggtgagccat cttcttcgcc
     3061 cattgctttg acgaattcgt cgttcagagt agggatgtaa gtttttggtt ctgtaccgct
     3121 ttttgctttc atattttcat tatattctgt atcatcttgt tttgatttac cgtctttgtc
     3181 gatataatca aagtttgatt cagttacttt gccgccagca actgtcattt cgaattgcac
     3241 acggtagccg ttagagtagt tcttttcttc aagcttgtaa gtgccgtctt tcaaatcagc
     3301 accattgtcg atttcgattg tatctgtgtt accagcttga gcagcttgga tcaattgttg
     3361 tgcgtagttt tggaagcttt cagatgagtg agtagctcca gttacgactt ccacaccgct
     3421 tgcgctttgt gcttttaaga attggtcatt caactcagga atgtattttt ctgggtttgt
     3481 gccagatttt gcttccatgt ttttgttgta ttctgcatct tttgtttttg attcgccgtt
     3541 ttcattgacg ttatcatatt ttgattcagt gattttgccg tcttttacaa ccatttcaaa
     3601 gactgcacgg taaccatttg aataattttt ttcttctaat ttatatgtgc cgtcttgcaa
     3661 atctccgcca gctacaactt ttgcagatga ttctgttgtg ctttttgcag tcgaagattg
     3721 tgctgtagat gattcagaag aagagtttga gcttccgttg tcatctgcgc cgcaagcgcc
     3781 taacactaga gctgaaaatg ctaatacggc aaatccagtt acaaaacgtt ttttcttcat
     3841 tttaataccc caccattcca tttctagtcc acaatttttc tttgtgattc attatacatt
     3901 ctaatctttt tagcctataa gtcaactatt tttgataaat aacccatgta atatttcaaa
     3961 cgttttcttt cagcaaattt cgtgaaaaaa cgctttattt taaaatttga aaaaaatcca
     4021 aaaggagtta gacaaaagaa cagaacatct atataatata tggagattgt gtaataagta
     4081 tcaaactaaa agaattatca tatattcatt atatagatag tctataagga gcggatgatc
     4141 aatggcaaag caaaatattg tcgttgtagg agcaggatat gccggtgttt cagctacaaa
     4201 atacttggca aagaaactga aaaaagaaga tgtagcaatt actctgatcg atcgtcattc
     4261 gtaccatact atgatgaccg agttgcatga agtagctggc ggacgtgtag aaccagaagc
     4321 aatccaatac gatctgcagc atttgtttgc tcgtcaaaag aatgtacaac ttgtcacaga
     4381 cactgtaatc ggtatcgata aagaacgaaa aatcgtcaag accaaattag gttcctatcc
     4441 ttttgatcag ctgatccttg gaatgggcgg agagccgaat gactttggta cacctggtgt
     4501 caaagcacac ggattcaccc tttggtcatt tgaagattct gtaaggattc gggaacatat
     4561 tgagaagaca gtagcaaaag ctgcattgga accagatgat gaactgcgta aagccatgct
     4621 gactttcgtt gtctgtggtt ctggatttac cggtattgaa atgattgggg aactgatcga
     4681 ctggaaaaat cgcctagcca aagattataa attagatcca aacgaaatca cactgatggt
     4741 cgtagaggca atgccgacga tcttgaatat gttggatcga aatgatgctg caaaagctga
     4801 acgctatttg cgtaagcaca acgtggaatt attattgaat gcaccaatcg tagaagtggc
     4861 tgctgatcat atcaaattga aagacggacg caacattccg actcacacac tgatttggac
     4921 agctggtgtc aaaggaactt ctgacgctgc tgactttgga ttagaatcag cacgcggaca
     4981 gcggttgatc gccaatgaat atatgcaggc aaaaggctac gaagataaaa acatctatat
     5041 cattggtgat ttagtctttt atgaagaatt cccaggaaca ccgacaccgc agatcgttca
     5101 agctgctgaa caaacaggac acacagccgc agcgaatatc gtggcttcga tcaaaggcgg
     5161 agaaaagcat aaatttaaag gaaactatca aggatttatg gtttctattg gtgccaaatg
     5221 gggggtagct aacctatttg ataagatcca tttaagcgga tttttagcta tcgtaatgaa
     5281 acatatcgtg aatttgaaat acttctttga tattcgttct ggttattata tgttccaata
     5341 tttaatgcat gagtttttcc atatcaaaga tgatcgcaac gtgactcgag gacattcttc
     5401 tcgttacggc aatgtcttat ggagtgtgcc acttcgtatt ttctatggtt tagtttggtt
     5461 cgttgaagct tccaaaaaaa tcattgggaa tggtgaagtg ttcaaaccaa gtacttggtt
     5521 tggtgaagga tcatggttca ctggaaacag tgtgttccct tggacatggg aatacaatgt
     5581 aacagatgtt gccagtggtg cttctgctgc tggtgatgca accacagctg ccagcggagc
     5641 aggggcaagt gccggagaag cagcgactca agctgcacat tttggtttga gttatgcata
     5701 cggtgaagaa ccaatggctg tgattgagaa gtcaccagac tggttcacaa agatcatgca
     5761 agtgatcatg ccaaacaatg atgtagcaat gttcttccaa aaattcatgg tattctttga
     5821 aattgccttg gcattagcat tgattgctgg attattcaca tggctatgca gtgcgacaac
     5881 gattgtattg gtgatcacgt tctgcttatc aggcatgttt tactgggtaa acatttggtt
     5941 catttttgtt gctttcgcat tgatgaacgg ttccggacgt gcgattgggt tggatcgctg
     6001 ggtaattcca tggctacaac gtacactagg taattggtgg tacggtagac caagttccca
     6061 gtacggcaag aaataaatag ataaagaacg ttatttgaat gcaagatttc aatagaaagg
     6121 ggctgagaca aaccgtcaca gcctcctttt tatgtaaaat taaaggaata agatgcccga
     6181 gataagcctc catgagcaag acacaggtgt cacaacctct gttacaacct cttgttataa
     6241 acggtgttcc agaagtagct tcttcgaaaa ataagccgaa atttcacaaa aacttgaaaa
     6301 gtaattttcg taaattcctt cttatttctt gaagttgccc acttctgtca caacctcttg
     6361 ttataaacgg tgttccacct gctgcttctc ggtaataagc ccaaagaatt agaaaacatg
     6421 gaaagctgtt ttctattctt cgttcttatt actcaaagca agacacaggt gtcacaacct
     6481 cttgttttta tgctaaaatt gggtgagtta atctggaaaa aggagaacaa aaatgagcct
     6541 taaagaattt gctgaaaaaa gtctgctcaa accttgggat gtttttatta ttttgctttt
     6601 gactgttctt tcttttttac cagtcatgat ttttggtctt cagcaaaaca ccgcaacagc
     6661 agaaaaagaa gcggtactgc gtgtggatgg cacagaaatc aaaacattcc ctttgatggc
     6721 tggagaagag agcaacacat atacttacaa agatgaacac ggagattata acttgatcga
     6781 gatagatggc gatcgagtac ggataaaaga agcagattgc gatgaccaga tctgcgtacg
     6841 tcgaggctgg gcaacgaaaa atggcgaaac catcgtctgt ttgccacata aattagtgat
     6901 cgaagtccgt tcaacagatg gaggtgacga agacagtctg atttattaga ccttcacaca
     6961 ccatgagtaa attacaaaaa atgatttata tttcgctact tgttgcacaa ggagtgatca
     7021 ttggtttatt ggaaaatatg atcccttatc ctttttcttt tgcgcctggt gcaaaactag
     7081 gcttagccaa tctaatcacg atcgttgcca tttttaccat gaaaaaacga gacagcttct
     7141 tactactttg gctacgacta ttcctgacta ctttgctagg cggaacgatt tccacattcc
     7201 tttatagtat gagtggtgct ttgcttagtt attttggaat gttattggtc aagcaattag
     7261 gaccaaaacg tgtcagtatc atcggaatta gtgcggccgg cggtttcatg cataatgtcg
     7321 gacagctttt gatggcttct ttcattgcac aatcatggac agtcatgttg tacttgccag
     7381 tcctttcagt tttagggatt ttatcaggga ttgcaatcgg gatcgcagcg aattatcttt
     7441 tacgacatgt gcagacactt caacgattcc aaaaagatta tgagcaggga accaaacaaa
     7501 aatggagccc aatgtttacc aaaaaataat cgtcacacaa ggagtttttt tatgaagcta
     7561 catccaatgt gggaaaacta tcctgcttta agtaaagaat tgacagaaac actaaaacgg
     7621 atggaagaaa ctgtccgcct gaaaaacaaa cctgtcgaac aagcaatcaa agaaacgatc
     7681 catgccggcg gaaagctgtt gcgtcctgcc tatcagctat tgttctcaca atttggacca
     7741 gagcaagatc gagacaaagc catcgctttg gcagcttcta tcgaaatgct ccatacggcc
     7801 acactgatcc atgatgatat cgttgatgaa gcggatctgc gacgtggtca gcctaatatc
     7861 cgtagtcagt ttggtaatgt cgtttctgtc tatgcaggag actatttatt tgtctgctgt
     7921 tttaaactat tgtctgatta ctccacttcc ttgaaaagtc tccaattgaa ttctcgcagt
     7981 atggaaaaag tattgaatgg cgaattaggt cagatggatg atcgctataa ttatgaactt
     8041 tctgtaaaag aatatttgga aaatatttca ggtaagacag ctgaactgtt ccaattaagt
     8101 tgttctgttg gcgcttttga aagtggaaca agcgagcgct tcgcaaaaaa agcaggagat
     8161 atcggacttt ctatcgggat ggcctttcag attatcgatg atattttaga ttatacaaaa
     8221 gagagccagg aaatcggcaa acctgtacta gaagacatgc gtcaaggggt ctattcttta
     8281 ccgttgatct actctttgca aaaaaacaaa ccaaagctac taccttattt agagaagaaa
     8341 gcggcaatga cagaagaaga tgtcgacgcc gtacgcaaaa tcgttgaaca tacaggaggc
     8401 gtggaagaag ctaggaagtt agcggcctct tacacagaaa aggctttgaa ggaaataaag
     8461 aaattacctg ccacctctct tcgaacaaaa gagaatctct tttcccttac ccaactgatt
     8521 ttggatcgca aagactgaat agggaaaggt tcgatacgta aataaatttc tcagaaggaa
     8581 atctacgtgt tttttgacaa attgaattgt agttcttgta tttatgataa aaagcaaaaa
     8641 taaagagcaa cgtccgttag cgacgttgct cttttttatc ttgaatattt ttttaccttt
     8701 tcgatttctt ataactcata aaagtgattc ttaaaccgat tacaagtaat ataacgcctg
     8761 cgagtgttat ccaattattc gattgacttc cagttttagg aagtgctctt tttgatttgt
     8821 ttccattgtc attgcttgtt ttattagtta agttaaagtt cgtcctgtta tccgaacttg
     8881 tttttgagaa ggagacactt gcatgacgtg tatcgcttgt ggtagacgac gtgtctgtac
     8941 tatcgcttga agttgatgaa tctgagctat cacttgtggt agaggatgta tctgtactgt
     9001 cacttgaagc tgacgtgtcc gtgctatcac ttgtagtggt agatgaatct gagctatcac
     9061 ttgtggtaga ggtagtatct gtactgtcac ttgaagctga cgtgtccgtg ctatcacttg
     9121 ttgtggtaga tgtatccgta ctgtcgcttg aagctgacgt gtccgtgcta tcacttgtgg
     9181 tagaggtagt atctgtactg tcacttgaag ctgatgtgtc cgtgctatca cttgtggtag
     9241 aggtagtatc tgtactgtcg cttgaagctg acgtgtccgt gctgtc
//
LOCUS       DAZULR010000076         8947 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.080, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000076 DAZULR010000000
VERSION     DAZULR010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8947
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.080"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(15..1154)
                     /locus_tag="ACG8ZV_002493"
     CDS             complement(15..1154)
                     /locus_tag="ACG8ZV_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HFS4997759.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
     gene            complement(1553..2851)
                     /gene="eno"
                     /locus_tag="ACG8ZV_002494"
     CDS             complement(1553..2851)
                     /gene="eno"
                     /locus_tag="ACG8ZV_002494"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000015 - phosphopyruvate hydratase
                     complex [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HFS4997760.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            complement(2967..3722)
                     /gene="tpiA"
                     /locus_tag="ACG8ZV_002495"
     CDS             complement(2967..3722)
                     /gene="tpiA"
                     /locus_tag="ACG8ZV_002495"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HFS4997761.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            complement(3826..5016)
                     /gene="pgk"
                     /locus_tag="ACG8ZV_002496"
     CDS             complement(3826..5016)
                     /gene="pgk"
                     /locus_tag="ACG8ZV_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HFS4997762.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            complement(5126..6127)
                     /gene="gap"
                     /locus_tag="ACG8ZV_002497"
     CDS             complement(5126..6127)
                     /gene="gap"
                     /locus_tag="ACG8ZV_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFS4997763.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            complement(6168..7259)
                     /locus_tag="ACG8ZV_002498"
     CDS             complement(6168..7259)
                     /locus_tag="ACG8ZV_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HFS4997764.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            complement(7408..8742)
                     /gene="rpoN"
                     /locus_tag="ACG8ZV_002499"
     CDS             complement(7408..8742)
                     /gene="rpoN"
                     /locus_tag="ACG8ZV_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HFS4997765.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            8802..8873
                     /locus_tag="ACG8ZV_002500"
     tRNA            8802..8873
                     /locus_tag="ACG8ZV_002500"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:8835..8837,aa:Arg,seq:ccg)
BASE COUNT         2321 a         1896 c         1648 g         3082 t
ORIGIN      
        1 ttattaaaaa aatcttacgc taagtaggat aaaataattc cttgatattt ttcgatcata
       61 tccaaataat tatcgatttc aacatactca tctacttgat gaggcaaagt aacgacacca
      121 ggcccaaaga cgacaaagtc gaaggaatgg ttagctttcg taaattcggc tgcatccgtt
      181 gttgctgccg ctccaactaa aggtaatggc tggctgaatt gttgctgaat gcaatgaatc
      241 aaaggagaat ctggatcagc tttgacaggt attttgttgt aatcgatcat caattccaaa
      301 tgatagtctg tctcttgatt caattcattg acgattgatt gcagcaatgc aatgatttta
      361 tcatttgggt attctggaat cgatcgaatg ttcccttgga gctgcgcatg gcttgggatg
      421 ctgttgactt gattcccgcc actgatcaat gtaacattat ggattgtttt tcctaggaca
      481 ggattctcga ttgtttcagc gaggtgattc atttcagcat ttgctttcgt aatgaattca
      541 tttaggtgat tgattgcatt ataaccttgg tctggcatag agctatgcgc ttcttttccg
      601 tgcgaggtga ctgtatagtt gattgatccc atgtgcgtat acatcaaact gtaattggtt
      661 ggctctccga tgatcaaggc atctaagtca tctacatagc ctgctttcgt gagctgttcc
      721 ccacctagtt cacccacttc ttctccgaca gtggctaata atttgactgt tccgttaaat
      781 ggttttcctg actctttcag ttcgatcatg gcaatcacca ttgctgccaa gccactcttc
      841 atatctgtag caccacgtcc gtacaaacgg ttcccatgga tttctgctgc aaagggtgca
      901 taggtccaag acgattcatc accagccgcc acgacatcca tatgcccaga taggcctaac
      961 acttttcctg attggccctt ttggtaacga gcaatcaaat tatctctacc atctctgtaa
     1021 gaaacaatct ctcctgttat gtcatgcttt gccaaaagct tattcaaata ggctgctact
     1081 tcaccttcgt ttccattcac tgatttaatt cggataatct cttgtaaaat cgcgattttt
     1141 tcttcttttt tcatctaatc ctctcccttg ccatttcttt ttattgtatt tgagtgtgct
     1201 cgaattttca aataggagca accaaagtaa aaatgaagaa agagagccac tttatgaaaa
     1261 atatgctgct acttccctcc tattttattt atacgagagg acttgcccat agattcctat
     1321 tctactgttc tatccttaaa agctcttata tgatgctagt tattgttagc tttccttttt
     1381 caaggatgat cttttcttgt accattcttt gtaaacatca tatacagaag ctagttgcaa
     1441 aaaaactctc tacctgctga tatttcagca agtagagagt tcgattactt aactaagtga
     1501 tcatactcga ctatctttca atagtcgatc atgtatcttc attagaaaag aattatttgt
     1561 tttttaagtt gtagaaagat ttcaaacctt tgtattctgc aacttcacca agttggtctt
     1621 cgatacgtag taattggttg tatttagcaa tacggtcagt acgtgataga gaaccagttt
     1681 tgatttggcc agcgtttgtt gcaacagcga tatcagagat tgttgaatct tctgtttcac
     1741 cagaacggtg agatacaact gctgtgtagc cagcttcttt agccatttcg atagcttcga
     1801 aagtttctgt taatgtaccg atttggttca ctttgataag gattgagtta gcaattcctt
     1861 tttcgatacc ttcagataat ttttgagtgt ttgttacgaa caagtcgtca ccaactaatt
     1921 gaactttgtc gcctaatacg tcagttaatt tcttgaatcc gtcccagtcg ttttcgtcta
     1981 atccatcttc gattgagatg attggatatt tagaaactaa ttcttcgtag aatttgatca
     2041 tttcgtcagt tgttttttcg ccttcgcctg agtcagctag tacgtaaaca cctttttctt
     2101 tgtcgtagaa ttctgaagaa gcagcatcca tagcaagaac aacgtcttta ccaggtacat
     2161 agccagcttt ttcgattgct tcgatgatta cttcaaaacc ttcttcgttt gaaccaaggt
     2221 ttggagcaaa tccaccttcg tcaccaacag aagttgctaa tccgcgagct ttcaagattg
     2281 aagctaatgc gtggaatact tcagcaccca tacgtagagc ttctttgaat gttggagcgc
     2341 caacaggcat gatcatgaat tcttggaagt cgattgagtt atcagcatgt gatccgccgt
     2401 tgatgatgtt catcattggt gttggcaata cttttgtgtt gaatccgcct aggtagtggt
     2461 ataaaggtac ttctaggtag tcagcagctg cacgtgcaac agcgatagaa acacctaaaa
     2521 tagcgttcgc acctaattta cctttgttag gagttccgtc taaagcgatc atagctttgt
     2581 cgatagccat ttggtcacga acatcgtagc caatgattgc ttcagcaatg atgttgttta
     2641 cgttgtcgac agctttagtt acacctttac cgccataacg agctttgtct ccgtcacgta
     2701 attcaactgc ttcgtattca ccagttgaag cacctgaagg aaccattccg cggccaaaag
     2761 ctccgctttc tgtgtatact tctacttcga ttgttgggtt accacgtgag tctaagatct
     2821 cgcgagcgta aacatcagta ataattgaca tgttttgtct ctcctttgag tttgtttttt
     2881 cctaagggat ttccctcata tacgatttta gttaattttg ctcattagtg caaacatttc
     2941 ttgcattttt cgcaaatttt caacaattat tttacagcgt ctaacaatga caagaatgaa
     3001 tctgcttgca agcttgcgcc accgactaaa gcaccgtcaa cattttcttt tgccatgtat
     3061 tcagcaatat tttctggttt tacagaaccg ccgtattgga tacgaactgc ttctgatact
     3121 tcttttccat aaagtttttc aactgtttga cgtacaactc cacaaatttc gtcagcgatt
     3181 tgtgcgtcag ctgatttacc agtaccgatt gcccagattg gttcataagc aataaccatg
     3241 tttgacacct gttcagctga aagatcagct aaaccagctg taatttgtcc ttcgatccat
     3301 tcagcagttt tgcctgcttc ataggtttct aaagattcgc cgcagcatag gattggtgtc
     3361 ataccatttg caaagatagc tttcgctttt ttattgatgt cttcgtctgt ttcatggaaa
     3421 tattcacgac gttctgaatg tccgatgatc acataatgaa cacctagatc agcaagagct
     3481 gctggtgaag tttcaccagt gaacgcacct gagttttccc agtagcagtt ttgtgctgag
     3541 atttttagtt ctgtaccttc agctgatgtc attaattctt gtaagaataa tgcaggagat
     3601 ccgatgactg aatcaacttt gtcatttgaa gggattttgt tttttactgc ttcagcaaat
     3661 tcttttgctt ctgatgcagt tttgttcatt ttccagttac ctgcgataat aggtttacgc
     3721 attgaggaac acactcctta atttattgaa aaatggctag ggagtcatga aaactccctt
     3781 caccttttgt tcgattactc gtcagaattg agcaaacttg gtcgtttatt tatcgttgat
     3841 tgctgctagt cctggtaatt ctttaccttc aagcaattcc aagcttgcgc cgccacctgt
     3901 tgagatgtgt gtgaatttgt cagcaaatcc taattgttct gctgctgcgg ctgagtctcc
     3961 gccaccgatg attgttgttg cgccttctaa gttagcgatt gcttcacaaa caccgattgt
     4021 acctttagca aagttactca tttcaaatac acccataggt ccgttccaaa caactgtttt
     4081 tgcaccttgt aatgtatcag caaataattt tactgatgct gggccgatgt ctaaagccat
     4141 caaaccatca ggaatgtctc cttcgattac ttgtgtttca acatcatttg aaaattctgg
     4201 tgcacagaca ttgtcgattg gcaagacaag tttgtcgcct gctttttcga ttaattcttt
     4261 tgctagttcc actttatcag cttctactag agagttaccg atcttgattc cttttgcttc
     4321 gtagaatgtg taagtcattc cgccaccgat caagatttta tctgctttag gaatcaagtt
     4381 ttcgattacg ccgattttat cagaaacttt tgcgccacca aggattgcaa tcattggtcg
     4441 ttttggttct tctactgctt caccgatgaa cttgatttct ttttccatca agaatccagc
     4501 aactgttggg ataccagttg aagcgatacc tacgttagaa gcatgtgcac ggtgagctgt
     4561 accgaaagca tcgttaacaa atacatcgcc taatgaagcc cagtatttac ctagttctgt
     4621 atcatttttg ctttcttttt taccgtcaat atcttcaaat cgtgtatttt cgaatacgac
     4681 aacgtcgccg tcattcatgt tgcggattgc ttcttctaat tgttctccgc gagtttcagg
     4741 tacgaatgtt acttctttac ctaataattc gcctagacgt tttgcaactg gagctaaaga
     4801 ttttccttct ttatcttctt ctgtttttac acgtccaagg tgagagaaaa ggattgcttt
     4861 tccgccttgt tctagaacgt agttgattgt tggcaatgct gctttgatac gagtgtcgtc
     4921 agtgatcacg ccgtctttca aaggaacgtt gaagtcaaca cggacaagaa cttttttgtc
     4981 ttttaaatcg atatctttca ctgttttctt agccatttta tttcctcctg aataaactta
     5041 ttatcaaaaa aagcggaaga agcgcgattg cttccccgct tttaaatgta catgtctata
     5101 atttacactt gtacgtttgt ctatcttata agttagcgaa gtattctaaa gtacgtacta
     5161 attgtgcagt gtatgacatt tcgttgtcgt accaagcaac agttttaact aattgtttgt
     5221 cgccaactgt cattacttta gtttgtgtag catcaaataa tgaaccgtaa gtcataccaa
     5281 cgatatctga agaaacgatt tcgtctgtgt tgtatccgta agattcgttt gaagcttctt
     5341 tcattgctgc attgatttcg tcaacagtta cttctttttc aagaactgtt actaattctg
     5401 ttaatgaacc tgttggtaca ggaacacgtt gagcagctcc gtctaattta ccgttcaatt
     5461 cgggaattac taaaccgata gctttagcag cacctgttga gttaggaacg atgtttgcag
     5521 cagcagcgcg tgcacggcgg aagtcacctt taggatgagg tccgtctaga gtcatttggt
     5581 cacctgtgta agcgtggata gttgtcatta atccttcaac aacaccaaat ttgtcgttca
     5641 atgttttagc cataggagct aaacagttag tagtacatga agcacctgag ataactgttt
     5701 ctttaccagt taatgtttcg tggtttgtgt tataaacgat tgttggaaca tcgtttccgc
     5761 caggagcaga gataacaacg cgtttagcac cagctgttaa atgtttttca gctgctgatt
     5821 tagaagtgaa gaaaccagta cattctagaa cgatatctac gcctagttcg ccccatggta
     5881 attcttctgg gttgcggtta gctaatactt taacttcttt tccgtttacg ttgaatgaac
     5941 cttcatgaac ttcaactgtt ccgttgaaac gtccttgagt tgtgtcgtat tttaacaagt
     6001 gtgccaacat tttagcatct gtcaagtcgt tgattgctac tacttcgatt ccatctacat
     6061 cttggatacg acggaatgct agacgtccaa tacgtccaaa accattaata cctactttaa
     6121 ctgtcattta agatttcctc cttatgaaaa tcaaaaaaat atttatttta aagggttacc
     6181 ccttttaaaa tctcatttgc agcagcttca tcagtgatga gccacgtttg ttttggtgca
     6241 tttttcatat aagctcgaat tgctttagct tttgattttc cgcccgcgat tgccatgatg
     6301 atcgggactt tttccaaatc ttgcaattct atgccgattc tagggacctt ataaacgact
     6361 tcaccttttt cattgaaaaa gtagccaaaa gattccgcaa cagcatttgc ttgtttcagc
     6421 atgactaatt ctttttcagt catcttacga cgtgctgcca tgtgtaatgc acgcccaata
     6481 ctatgaataa cacaattcgc ttcactaatc aagtttaaga cttcttggat agatggctca
     6541 ttgagtaaag aattgtaagt tgccagactt aattgttccg gaacataaag tgcgcggtgg
     6601 ttaccgtttg ctttagcagc cattcttgca ctgacagaat ttgcctgtac agttatcgct
     6661 tcaccaatcc cgcctcttgc agggacaaac aggttatgcc gtttcttatt ttccagatta
     6721 gacaattgtt cggctaccac agccatagta gttcctccca tcacagcgat gatattctcg
     6781 ccttctggaa gtagtcggtc taaggcttcg ctcagcgctt cgccgaatgc atcagccact
     6841 ttggtctgct cttcgctgtt tcctgaaaca acgatacagc gttggttacc aaaatattct
     6901 gccaactgtt gttcggtttg atgcgtacct aaaagctgat ccatgaagtt ttcaaggctt
     6961 tgataaactt cttcgccctt agttgtcagc gtcataccgc tttttgaggt gtcgatcaaa
     7021 ttcagatttt tcaaaaggtc tgtttctgtt cgtaagactc gttctgtgat ccccatactt
     7081 tccgataaac ttcgacgccc aatcggctgc atccaataga tatttcgtaa aattttatag
     7141 cgttcttgca acacttcgat aatatctggt gcaacagatt caatcatttt tatttcatcc
     7201 agcatagcga tctccttagt tggacacttt acgtccaatg tagacttaaa acgacccata
     7261 tacgataaaa aaagaaatta actattcgaa tttcacatca ataaagggaa atctcaacct
     7321 cacgactgta agtctaacag ttttgctctc gtttttcaac taaaaagact agaaaaagtg
     7381 aaatactttt tctagtcttt tgactgatta gttatcataa cgttttcttt ttgatgaact
     7441 cgggattcct aataaatcac gatattttgc tactgttcgt cttgagatcg ctatctcatc
     7501 ttttttcagc aattcaacca atttctggtc agacaacggc ttgtttttgt cttcttgatc
     7561 gactaattcc tgcagctttt tcttcgctgt atctgctgaa aggtcttctg tctgttctgt
     7621 actattcgta ggaattcgtg tagtgaaaaa tttttttaat tcaaatacac cgaagtctgt
     7681 ttccaaatat ttcccgttga ctgcacgact gaccgtggat tcatgcacat ctatctcagt
     7741 tgcaacttcc tttaacgtaa gaggcttgat tggacgttcc ttgtcgataa agaaagcttt
     7801 ttgccgggaa acaatgactt gagcaacccg caaaattgta tccccacgtt gtaggatcgt
     7861 tttcttcaac cattcgaatt cctgtttccg ttcttttaaa taattttcag tttctttatc
     7921 tgcttgttgt gacatttgtt tgaagtaact ctcttgaaag cgtatatttg gctgattttt
     7981 tcggtttgag ataacttgta catttttatc gtcgtccact aatacccgga catcaggaat
     8041 aatgtacaat tcgctgctac ggtcgaaaat ccggccaggg cttggactca acgtttgtaa
     8101 atagtcgaat atctgctgaa cagcatgtag atcaacagaa aaacgttgtg cgatttcttt
     8161 ccattttcgc tccaccagtt cctcaaaaca ttcttccaac acgatataag ctaattccgg
     8221 cgcataatca tctcgttctg tttgaagcat gagacattct tgcaaactac gtgcacctac
     8281 tccagctggt tctaattgct gaatcagagt taacgcatcg agcatttgga taggcgtagc
     8341 tccaatctct tttccggctt cttctaaact aatcgtcaaa aatccgttca aatcgatgta
     8401 ttctacaaga taaagaacga ttttcctcaa aaaagtatct cggtaattca aatggacttg
     8461 ttcgatcaat gaatcaaata aagacccttt tgtatcagga atctgattta ggtaatttgt
     8521 ctcttctcct tcataagaag atgaagaagc ttttatgtaa tctggctgcc attccggctc
     8581 aacaacttcc accaatggat tttccattgc ttgattctca acgaatgcca acagctcctc
     8641 actgttatat tgtaaaactt ggatggactg ttgcaactgt tgcgtcatgg ctagtttctg
     8701 tgtctgctgc tgtttttgtg aaaaattttg ctcaaatttc atttttttgt ccaatcccct
     8761 tgtaattttt tatctgttta gttacaatta tcccagtgct tgcgtcctta gtgtagtgga
     8821 tatcacgtaa gattccggtt cttgagacgg gggttcgatt ccctcaggac gcgttctact
     8881 gctattttag cataatttac gaatagttgc ttctttattt ttaagtgaaa actgtccgcc
     8941 aaagaaa
//
LOCUS       DAZULR010000077         8873 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.081, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000077 DAZULR010000000
VERSION     DAZULR010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8873
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.081"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(488..712)
                     /locus_tag="ACG8ZV_002501"
     CDS             complement(488..712)
                     /locus_tag="ACG8ZV_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997766.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            903..3680
                     /locus_tag="ACG8ZV_002502"
     CDS             903..3680
                     /locus_tag="ACG8ZV_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFS4997767.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            3761..4180
                     /locus_tag="ACG8ZV_002503"
     CDS             3761..4180
                     /locus_tag="ACG8ZV_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFS4997768.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            4192..4662
                     /locus_tag="ACG8ZV_002504"
     CDS             4192..4662
                     /locus_tag="ACG8ZV_002504"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFS4997769.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            4679..5458
                     /locus_tag="ACG8ZV_002505"
     CDS             4679..5458
                     /locus_tag="ACG8ZV_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFS4997770.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            5445..6266
                     /locus_tag="ACG8ZV_002506"
     CDS             5445..6266
                     /locus_tag="ACG8ZV_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFS4997771.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            6283..7332
                     /locus_tag="ACG8ZV_002507"
     CDS             6283..7332
                     /locus_tag="ACG8ZV_002507"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFS4997772.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            7345..8349
                     /locus_tag="ACG8ZV_002508"
     CDS             7345..8349
                     /locus_tag="ACG8ZV_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFS4997773.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
BASE COUNT         2960 a         1468 c         1835 g         2610 t
ORIGIN      
        1 tttaatttgt tcttgcaatc ttttttgcta cgtaattttt gtaaaaaagt gggttgagag
       61 aaatctaatt gattttcaaa gaaggagtat gaaaatgaga aaaatattta ttcgtttatt
      121 gtgggtacta tcttagagga ataaataata gtggagaaaa ctatggtttg gcgcagattc
      181 tatcaggttt gatggaacga agacaacctc ccgacatcaa gtcaaaagct acttgagatt
      241 ttgatctgaa aataaaaaaa gaaaacaagg taggaacatc aatgtttcta ccttgttttc
      301 gtaatcaatg ggaaaaaact aagagtggtg tacgtaatca ataaaaagga tggtgacaac
      361 agtacctctt tactctctga aagcatcata actcgttttt cctcattatg ccaataaatt
      421 gttgttatac cacatataag gatttgtaat agctaaaaac agacaggaaa gttgaaatct
      481 gtgaatctta ttttgtatgg aaggatttat agaacgcaaa aatcaagata aagatgaata
      541 aaaatcctgt ttcggctata tattgcgtat ctacgccaat aaaacgagtt tgttctgtca
      601 tagccatata aagcaaaggc aaaaatacaa ctacagcgag ataagatccg atgatttctc
      661 gaaaagtttt ccaggaagta tgtttcctgt ttttatattt atccgatttc attgaatagt
      721 catagcctcc ttattctttc atatgttgaa attccagtat aaaaactgga aggaactgta
      781 cgttttttag aataaaaatt ataagggata agtaggctgc tgtctataat aagatatatt
      841 tttcaattct ttattaaaga ttttattgac aaaatgaatc cgttttctat gatggaggag
      901 gggtgaataa gttgttgaag aaggaaattt tatgttactt agagaaccag acagcctttt
      961 tcgatttaga acatatgaac gaggtcttta cagcacaaag gttagctgat cattttgggg
     1021 taaaaagaaa cacagtcagt cattatttga accagttaaa tgatgagcaa ctactagtca
     1081 aaatcaattc tcgaccagtg atttatttcc acaaagaagc ttttgaaaaa caatttttta
     1141 agttacgcac gaatttttat ttttctatcg atgatctcaa agaggaacag ccttttttcg
     1201 cgcaaccaaa agacttattc tcttttatga tcggatacga cgccagtttg aaagaaagta
     1261 tcgaacaaat caaaacagct ctttactatc cagatggcgg attaccactt ttgattacag
     1321 gcgaaagtgg cacaggtaaa agttatttag ttaatttggt ctatcagtat tgtctgcttc
     1381 atgatctgct agaagattct gcaccattca tcacttttaa ttgtgcacaa tatgcagata
     1441 atcctgaact tttgactagc aatttgtttg gacatgttaa gggagcgtac actggtgcag
     1501 aagaaaataa aaaaggggct tttgaagcag cagatggtgg gatcttgttt ttagacgagg
     1561 tacatcgctt aacaccagaa ggtcaggaaa aactgttcac ctatcttgat caaggtgtga
     1621 tttatcgtat gggagaacct aatttgtcac gccggatcaa aacacgtctc ttttttgcta
     1681 cgactgaaga gattactagt catttcttaa caactttcat tcgaagaata cctatccgaa
     1741 tcgaactacc tgcacttaat cagcgtagtc gtaatgaacg gctagaactg atttactctt
     1801 tttttctcga agaacaaaga aaaatgggga gccctttgtc agtcagtgga ccagctttgt
     1861 cacttttaac aagtcagaaa ttatccggaa acataggaga gctgaaaaat atcgtcaaag
     1921 tttcagcagc aaaagcatat gctgaacagc gtgaacagcc tgaaatccat gtcacgatcc
     1981 atcatttgca aaaagaacta cttgcgcagc ctattactaa aaatacagca cagcaaggaa
     2041 tctatattac gcaagaccag accttagagc aattaatgga gaagcaacag cccgaacagc
     2101 agcgaatcgt taaaagtttt gagcaaatcc taattgattt caagaaaaat aactgtctgc
     2161 tatattcttg cgaaggaaaa ttaaagcaag aagtgattca attatttgat tttttgctgt
     2221 ttgagaccag tagacaagaa aaacacgagc tgctggttta ttggacacaa tctatccgag
     2281 agacctttcg acaaatggaa actgcctatc aaatcaaatt cgatggaaac agtgtctatg
     2341 ccttgagtta ctatctctat cagcgaagca ctatcaaatg gttaccggaa gaacatgata
     2401 ttatccaact aatcaaagaa ttagaacaac aagtttctca gtcttatcca tctagttatc
     2461 actatgtcca acgaattctg gaattaagta agatcaaatt agatattgaa gacacaagta
     2521 tggatcggat tttactgacg atctatctaa aaaaagcgaa atggtcaaaa gaaaaacgac
     2581 tgccaaaagc gatgattgct gctcacggtt atgcaactgc tagcagtatg gcaaatgtag
     2641 taaatcgttt attacaagag gatctatttg aatcatttga tatgccacta gatgtcacac
     2701 cacagcagat tgcttcagaa atccttgatt attgcgaaaa cagcgatgtt tcaaatggat
     2761 tgatcatatt agtagacatg ggatctctga aagaaatcca tcagtttttt aaaaaacagt
     2821 tatccgtacc gcttttgatt ttgaataatg tgacgacacc tttagcaatc acagtagggg
     2881 aatgcctgca aaaaaatgta tcattagaag agatagcaga agagactgtt cgacagatcc
     2941 agccagaatg gcgactgctc tatccagagg aaaacaaacc caaagcactc attactactt
     3001 gcttcactgg aatcggtacg gcggtccact taagtgaact gctagaaaaa agcttaccta
     3061 cggcttgtca gttgaaaatc atcccatatg aatatcagca attaaaagat aagaaaaaca
     3121 gtgacccatt attttccata tacgaagtcg taggaatgat tggcaccaca gatcctgata
     3181 tcaccaatat cgactatctt tcattagaag acctcatctc gggggaaaag atgtctgtac
     3241 tagctgaatg gttggacact actatgaatg cttcagagaa ggaaatattc aatcagcgca
     3301 tcattcgtaa tttttcattg gaaaaagtac tggattccgt gactattcta gatacagaga
     3361 aggtgatggg agaaatcgat cattttatga gagaattaga ggtgcagttg aatcgaagca
     3421 tcagcaatcc caaaaaatta gcgttgtatg tccatgtgag ctgtctcatt gaacgattga
     3481 tccgacaaat gccaatcgaa acctatcaag gattagagaa atggaagcag tgtcaaaaag
     3541 aagggttatc tgctattaaa tctgcgttta gtgtcattga agagcattat agtgtcatga
     3601 tccccaattc tgagattgcc tatatctatg atattttgag tgaagataca gagtttctct
     3661 cgatagaaga agaattttga acataagcaa gttgttgcca ctaattttgg catgcaactt
     3721 gcttttttag tatgtgtaag tgaaaagagg agatgaaaaa gtggatagag aaattatctt
     3781 agcttcccat ggaaaatttg cttcagggat attagattca ttagagctga tctatgggaa
     3841 aaatcattct attactgtat tcgattgcta tactgatgag aattttgatt tagcggaaac
     3901 agtaaggcag ctttttatga ggtacaaaga taaagaaatc attgttctga cggatctttt
     3961 tggcggaagt gtcaacaacg aattcttaca atatatcaat cgggatcatg tctatctcgt
     4021 tgccggattg aatttgccac tattgattga gctagtatct cggttggacg ctgaagtaga
     4081 gacaactgtt ttgatccagc aggtgctaac tgattcaaaa aaaatgatcc agttttgtaa
     4141 cgagcggctc aatcagaaaa tagaagaaga cgaattttag gaggaagaaa aatgattgta
     4201 ttgacaagag tcgaccatcg gttattacac ggacaagtag ctttttcatg gacacaaaca
     4261 ataggcgcag actgtatttt gattgctaat gatgatgtac ctacgaatga gatacgaaag
     4321 acaacgatca aattagccaa gccacaagga gtcaaactag tgatcaaatc aattgatgac
     4381 tcgattgccg cgttgaaaag cggggtgaca gataaatata agttattcat cgtagtggaa
     4441 tcgatcgagg atgcatataa gctggcagaa gcgtatccag aaatcaaaac catcaactta
     4501 ggagggatca aggcaaaacc tggtactcgc agcatcggaa aagcggtaaa tattttacca
     4561 gaagaggagg aacgcttgaa acgattaatt gacaaacaaa tagaagtaga aatccgtcaa
     4621 gtaccagcag ataaaaaagt ggatgtaaga gaagttttgt aagaaaggaa gaacctcaat
     4681 gattgtacaa gcagtcttat taggaattgt tgcatttgtc gcacaatcag aatatgcact
     4741 agggacatcg ttgctttctc gtccgattgt gacggggctg tttacaggaa tcgtgttagg
     4801 tgatgtaaaa actgggatca ttatgggcgc aactttagag ttagcattta tcggatcgtt
     4861 ctcagtaggt gcttcgattc cacctgatgt tgtgaccggt gggattttag ggacggcttt
     4921 tgctattaca gctggagccg gtacagaaac cgcgctttta ctaggtttgc cgattgctac
     4981 gttgacattg atattgaaaa atatttactt agggcttttg attccaatta tgaaccataa
     5041 agcagacaat tatgcagaag aaggaaatta taaaggagtc gagcatatgc acttgcttgc
     5101 cggtatcggt ctttccttga tgcttggtgt tgtggtaatg gtttcttata tggtgggaag
     5161 caatacgatc ggaaatctat taaatatgat tcctgacttc gttcaaaagg ggttgtcagt
     5221 agctacaggg ttgattccag ctcttggttt tgcgatgctt gctcgtttgc tgatcaacaa
     5281 acaagttgca ccatattttt tcttaggttt tgctatagct tcttacttag agattcctgt
     5341 gaccggagta gctatttttg gtgcgatttt agcagttgtg gtagtcaata ttatgaatgt
     5401 ccgtcaacta ccacttcaaa caactgcagg ggaggtagaa gaagatgaag aattctgaga
     5461 tcaaaaacag caaaataacg aaaaaagagc taaatcacgt attttggcgt tcttttcaaa
     5521 tggagttttc ttggaattat gaacgtcaga tgaatatggc ttatgtttat gcaatgattc
     5581 cgattttgaa aaagttatat cagtcgaaag aagaaatggc agcagctttg aaacggcatc
     5641 tagagttttt taacacgacc ccacatatcg ttacactgat tttaggaatc acggctgcaa
     5701 tggaggaaga aaataaggat gatcctgaat ttgatgtgac tgcgatcgat agtatcaaaa
     5761 catctttgat gggacctctt gcagggttag gagattcttt cttttgggga actttgcgat
     5821 tgattgccac aggtgtgggt acctctttag ccatgcaagg aaatatttta ggccctatct
     5881 tgttcatttt gattttcaat attccgcaca ttctgtttcg ctatctagca acaggttggg
     5941 gatatcgctt aggaacgggt tttttgaaaa agatccaggc aaacggtatg atggaaagtt
     6001 tgacattagg cgcgtctatt attggactga tggtcgttgg agcaatgact gccacgatga
     6061 tcaccatcaa tattccttta aaaatcggtt caggagaaaa tgctgtgact gttcaaagta
     6121 tttttgatga tatcgttcca aatatcttat gtcttggagc atttggcata gtgttttatc
     6181 tattgaagaa agaagtgaaa ccattaacga tcttgatcgg actagctttc tttggaattt
     6241 ttggttcgtg gatagggatt ttttaaaaaa ggagcagaga aaatgtttac gatgcaagat
     6301 tatatctatg aagaaaagga agtactaagt acgatcttga aaaagaatga tttttcgaca
     6361 agagaacata tgaaaaaaac agtgaattta ctgatcttag caacgggttc atcttataac
     6421 gcttgtttag cagcgaagcc agcattggaa tcttatggtg atcttactgt cgatattcaa
     6481 gaaccttttt attttttcaa ttatggaaaa ctttctcctt caatcgatac tgtgattgct
     6541 gtgtcacaaa gcgggaaaag tgcttctact gttgaagcag taaaaatgat acaaaaacaa
     6601 gggttacctg ttgttgctat cacaaatgac gtgcaaagtc cacttgcttt agaagctgca
     6661 caaattattg atttaggtgc cggggtagaa tcagtaggct tcgttacaaa aggctattct
     6721 gcgactgttt tacagttact actcttaggg ataggaattg gaataagtaa aaataaaatc
     6781 agcaaaaaaa tagaacaaga ctacatgcaa cagttgcgca aaataatcaa ccatttacca
     6841 gcgattattc aaaaaacgga agaatttttt gatggatatc aaagtttatt tcgtttagca
     6901 cagcgtttcg tcaccattgg atatggtcca aactggggaa cagctaaaga agcagagacg
     6961 aaattgactg aaacaatccg cgttccgtca caaggatttg agttagaagc ttatatgcac
     7021 ggcccatacc tggaggcaga tgcttcgcat ttgctattct ttattgaagg ggaaagtgta
     7081 aataaggaac gttcgcaaaa gttgcaaaga tatatgagtc ggtacgttgg agagactctc
     7141 accattacca caaaaaaagc aagaaacgag aaaacacttg gattagcaat agaatgtgat
     7201 gaatatctgt ctgtattagc gcttgtcgtt ccgtttcaac tattcgctta taaaaccgca
     7261 gtagctaaag gtattgactt gaacaaaaag atttttgaag actttgatac agtcttgaaa
     7321 agtaaattat aagaggtgga aatcatgctg aaattcaatg aagaagaaca aatcaaagca
     7381 ataaaaggcg cactagcttt acgtccgcaa gtagaagaaa tcatcgataa actttatgcg
     7441 gaaaaatttg acgctgtcta ttatctagga atcggtggaa cgtatgcttc ctcgatgcaa
     7501 gctgtcactt atatgaatgg gaaaagcaac ttgcctgtct ttgtacagca tgctgcagaa
     7561 tattacacta ctggaaacaa aagattaaca aaagattcta tcgttatttt gtcctctgtt
     7621 accggtacaa ctcaagaagt agtgaaagca gtagaacaaa tcaagaaagt aggagcgaca
     7681 ctgattggat ttatcgataa agcgaacagt aagttgtctc agctatgcga ttttgtggtc
     7741 acttatccag ctcctggaac agaacaaatc aaatttttta tggcagcaga tcgattgatg
     7801 tatttgaatg gagaattcga agcttattca gaatactatg aacagctcga acgttattta
     7861 ccaacagggt tagtggaagc agagaaaaaa gcagatgcat ttggcttatc atttgcagaa
     7921 aaacatcgac gtgatagtat gcattatttt attggagcag ggaatcaatg gggagctgtt
     7981 tattcatatg ccatgtgtta ctgggaagaa caaagctggc ttccatcgaa atctatccat
     8041 gctgccgagt ttcttcacgg gacgttagag atcgtagaag aaacaacccc agtcacatta
     8101 tttttaggcg aagatgaaca gagagtgtta tctgaacgtg tggctaaact tttgccaaaa
     8161 atttgcagca attatacatt gatagacaca aaagactatc cagtagaagg tatcagtgaa
     8221 aaatatcgcg gacgtgtttt gtctttctta ttgatgcatg tagtgacaca acgcatcgat
     8281 gctcatgtgg agcagttgaa ctgccatcca ttagagatac gccgctacta tcgtcagttt
     8341 gattattagg atagactgga taaaaagaat ataaaaaata aagagagcag cgataactgc
     8401 tccctttatt tttttaaaat attggcatca attacgttat aaaacacatt ttttgcatta
     8461 tctacagttc aacttataat ctgtttaatg ggacatgtgg gtgccaacca ttttttgtta
     8521 tgcaatagta ctatttagtt gttgcatgga tccgtagtaa aagtccaagt acaacgagtt
     8581 gcgccagttt acatagcgtt ttgtatccag aatgttgact aaaacaaaag ttcctatgtc
     8641 aaccgtcaac agagacaatc tgtccgttgc aggacctgac agatttagaa atgttcaatc
     8701 tgtctcttat gtattttaaa tcaatactca ctaggagaag tttcctaacc tcctaatagt
     8761 aatgctggta gtaacattgt caaaactgct tcctcttagg aacaagcaaa gcataacgag
     8821 tgtaaaaata aaatgtagac tattgtaaca tatcattgat tatttcaagt aaa
//
LOCUS       DAZULR010000078         8582 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.082, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000078 DAZULR010000000
VERSION     DAZULR010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8582)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8582)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8582
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.082"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..161
                     /locus_tag="ACG8ZV_002509"
     CDS             <1..161
                     /locus_tag="ACG8ZV_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HFS4997774.1"
                     /translation="FSSLEKLGCQNFNSRSVKGLESRFESILLAYSVLLSRAQRRFKG
                     TLRYSLGY"
     gene            complement(127..1458)
                     /locus_tag="ACG8ZV_002510"
     CDS             complement(127..1458)
                     /locus_tag="ACG8ZV_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFS4997775.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIKPVVLVNFNILKNISKFL"
     gene            complement(1599..2201)
                     /locus_tag="ACG8ZV_002511"
     CDS             complement(1599..2201)
                     /locus_tag="ACG8ZV_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HFS4997776.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            2446..2652
                     /locus_tag="ACG8ZV_002512"
     CDS             2446..2652
                     /locus_tag="ACG8ZV_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997777.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            2964..3683
                     /locus_tag="ACG8ZV_002513"
     CDS             2964..3683
                     /locus_tag="ACG8ZV_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFS4997778.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(3764..4447)
                     /locus_tag="ACG8ZV_002514"
     CDS             complement(3764..4447)
                     /locus_tag="ACG8ZV_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HFS4997779.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            4665..6851
                     /locus_tag="ACG8ZV_002515"
     CDS             4665..6851
                     /locus_tag="ACG8ZV_002515"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HFS4997780.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            7197..7607
                     /locus_tag="ACG8ZV_002516"
     CDS             7197..7607
                     /locus_tag="ACG8ZV_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFS4997781.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            7621..7977
                     /locus_tag="ACG8ZV_002517"
     CDS             7621..7977
                     /locus_tag="ACG8ZV_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFS4997782.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT         3146 a         1402 c         1606 g         2428 t
ORIGIN      
        1 ttttttcttc cttagaaaaa ttaggttgtc aaaatttcaa ctcacgttct gttaaagggc
       61 tagagagtag atttgaaagc atattactgg cttacagtgt tctattaagt cgagcacaac
      121 gacgttttaa aggaactttg agatattctt taggatatta aaattaacta gcaccacggg
      181 ttttatttgt atataaatcg tttgagaaaa acgctggttt tcaattgatg tttcaaggaa
      241 aagataagga ttggtctttg tcaattcatc caagataaac aagccaaggc cttcgttttt
      301 tggatttgtt tttgttgaga accctttttg tttcaactgg tttaacggta atgtatttgt
      361 tgttgtattg atcacacgaa tcatcacgga atgattcttc ttgagtatgg tcaattcgat
      421 ttttttcttc tttgcagcac tagctccttc aatcgcattg tccaagataa taccaagcat
      481 acgtacaagg tttaccgtat gtttcgtatc cagttcgatt ggctcaggaa aatgaagctg
      541 gacgatcaac cctttttcct gtgccatcat gagttttaat gacagtaaac tacggatctc
      601 aggaactttc atattatcca acatacttag attggccgga aaaaggttca tcatctggcg
      661 tgtaggtaat atcgtttgat cataataaga ccgtaatcct tctaagtcgc cttctgaaat
      721 atagctgtga agagaaaaaa gcagattttg gtaatcatgt ttgaattctc tcaagtcttg
      781 atagtttttt tctagatctt tgatataatc ctgttgcatc ctgacttgtt gctctaataa
      841 ctgatcagct aatttcttat tagagatttt ccaataataa accaagatga tcaggccaac
      901 acacagatat agaatgaaaa aactcgtatt caaagctaag acatcaggtg tttcaccaga
      961 aaaacgggta taaaaaataa tgatatagta tgtaaataat atcaatgtcc cgatcgtacc
     1021 gatcatacgg cggtccacag tgtgaaacca agtctctaac gattttttta aacaaaaagc
     1081 taataaagca gataaaaaag cggataagac aatgtgaaaa tactgcaatg aatctcctgg
     1141 ttcaataacc gaagatttca aaacaaaaaa atcgccgatg cttgttaagt gatctcctaa
     1201 aagcgacgtc aataacccaa aaggaagcgc gtaaaccaat tgttgacgcg aagtcgaaaa
     1261 gaagaaaaaa gtaagcatca gcattcctat agcaattaga gcagtaaaaa tccctaaaat
     1321 cgaatagacc catccaatca aaatacaaga aatcagaatg actcccgcaa acagatattt
     1381 gtatcggatg tgatggtcaa tcaataagat acaaattgtg taaatcaaat attgcaacgc
     1441 tatggaccat aaaaacataa agtacagctc ccattgattt ttaccaaatt atagcacaat
     1501 tggcgtatta tttttttaat ttttcaggga ttttgaattc agaactcata ccaaagcagc
     1561 agccagatac aaaaaagtca gataagttag ttaattgttt aatgattgtt tttttcatga
     1621 aagattcctc caaaattcat caagtagttt gtaataggaa gcaacgtagc tatttctaaa
     1681 acaatcccaa gtagcaaata ggtagaaaag taagaagctg agaaaaataa cgtaatgaga
     1741 gaaaaaatta gaaacatgct gatcgccttc tttaataatg ggggacgttt ctcgggttca
     1801 atgggattga ttgctgtacc tcttgatcca tagcgaagca gtaacaaaaa gcagctgatt
     1861 aacaaaaaga ccatcattgg gaaggagata gtcaattgca gatgtttcat caccaaggga
     1921 acgccccata aataaagtag tgtccacagc agacaaacga attcagagtc ggaatgcaat
     1981 ccataagcat atctgcggat gcagatataa gaaagaaagg tgattcctgt ttccgcccat
     2041 gagcctgtca ccagagaaaa gactagaacg accgctagtt ttccaagatt attcaataaa
     2101 acttctaaga caaattttac ttggacatac accatatctt cttccgattt gtctccgctg
     2161 aataaggctt ctaataattt gttcacaact ttatctttca tctcatacgt acctccacca
     2221 caaattttat gctaaaaaaa ataaaaaacg tcttttgttt cataaaaagt ggttttgaca
     2281 tcaaaaccgt catgatctcc taaaaaaatc ttcgttttcc aagaacctta ccaaaaaaag
     2341 tgacagtttt gatacgaaaa gtacttttta tgacaagttt gtgctttttc gagtgattta
     2401 tgttaaaaaa ttactgacct tataaaaggt gatggaggga ttcttatgga aaatgaacaa
     2461 ttgtttgaag tcggcgaaac atatgcattt aaatctgatt tatttgaatc accaataaaa
     2521 ggaaaaatag aaaaaatcta tgaaaatagt gtgatgatac gtgtcatgaa atgcgcagta
     2581 gaagacaatg ataccgctca taatctgcac tggcagttag ttgtacgcaa atcaagtaca
     2641 atagaagaat aaaaacagat aaaatgttga gagcataaag aggttgtgag tctcccgttt
     2701 agctctgagt tacaaggaat aatgttaaaa aacagctttt catgttttat gaatattgcc
     2761 ttgtgaccga ggtgttggca ggagaatact gtttatttga aaaaagggct gcgacaagac
     2821 ttttgtcaca gcctttattt tcatgaatag gagttacttt tggctacttt tagagaagta
     2881 gcttttaagg agcagataaa gtcaaggctt ttatttctat aaatgaagta gtaaaatgaa
     2941 gaacagattt tattacagga aggatgccga taattgtgat cattgttgca ggaacgatcg
     3001 gtgcagggaa aagcacacta actgaaatgc ttgcccaaga tttagaaaca aaaccttttt
     3061 atgagaacgt ggaagataat gaagtattgc cgctatttta ttctaatcca gaaaagtata
     3121 cttttttatt acagattttc tttttgaaca aacgcttttt ggcaatcaaa gatgctttca
     3181 gccatgatga caacgtacta gaccgctcca tctacgaaga tagtatgctg tttcatttga
     3241 atgcagattt agggcgtgtt tctgaagtag aagtaaagca gtatgaaggt cttttagaaa
     3301 cgatgctgaa ggagttagaa gaaatttcgc cacaaaagaa accagatcta ctggtttata
     3361 ttcgtgtatc ctttgaaact atgttagcga gaatcaaaaa aagaggccgg gaatatgaac
     3421 agctagaaca agatcctgaa ctctattcct actataaaga actcaatcga cgatacgaag
     3481 agtggtatga acagtttgat atatgtccca aaatagtgat cgatggggac aaatatgatt
     3541 tcgtagccga tccggcatgt ggagaacaaa tcgtacaaga aatcaagatg cgggcaaaga
     3601 aaatgacaga agaggcagat gcccagtcga tccgctacac tacaaataac ccgaaagcaa
     3661 agggaatctt tacaactaaa taatataaaa actaagcaaa ttgctcactc gcagatattt
     3721 ctctgtgagc agcatcttgc ttagtttttt tgattcattg agatcaaata gtgaaccgat
     3781 tcgtatgata aaattgccat aaatgaaatg tctgagtgag ggccatgatc aaaaataaaa
     3841 tggaaacgat caaaatcgaa tgggcgccaa acagatgatg acagaaaaca aggacaatag
     3901 ctcctgcgat aaaggcaaga acgacactta gatagtggaa aaatcgatca aaatctgctt
     3961 tttctttaga aatacaataa tcatataagt tcgttgctac cccttttaaa tttccagttg
     4021 taaataaatt agtgtaggca cgcccgttga ttttatcaaa agctacccac tggatcgatg
     4081 cagtaaaagc aatcaaaatc gttactaatg cgggatgctc atggacgggt gtcaaactaa
     4141 caaagaaaaa aatcactgct tcataatata gaacaaacaa gcgccagaaa tgtttttctt
     4201 tttttctaaa ataatcaatt agatactttg ttagaagaat ccctaagaaa aagaaaaggg
     4261 tagacaatac ttttttacca acacttagcc attctccgtc aaatgcttgg atgatcgata
     4321 gaatgatatt gccagtttga gcagaggcaa aagcaccata ttggatataa gtataactgt
     4381 ccatggctcc tccgataaat gtcagcaaaa gtcctattgt acgcccctcg tgaaaggaag
     4441 tctgcatttt tttcatcacc ttttatgaat atttttgtct tccttatctt agcataaacg
     4501 attgaaaaaa aggaaaaatt ttcagaaaac taaaatcata tcgcttccca ttttcatttt
     4561 tagaaaggtc tgttagtata aagaaaaaat agacaacgaa actttaaata accaacttga
     4621 aataaacaaa ttcaaagaag aaagatggga aggaaatcaa tcagttgaat gaaaaagaaa
     4681 ttctccgatt acaaaaagaa ttgaaacgct gggagaacaa gtataaaaag cttcaacaag
     4741 tctttcggct acaagaagaa atcattgcta cctatgaagc ggcttatggc gaagcacccg
     4801 gacttattga ggaagaagta caagtaaaag aaagtgaagg aaacagctct ttctttaaaa
     4861 tgatggagaa acgttcctat aatcgcttca atcaagaaca aaaagcagct atcacatatg
     4921 atatgaagaa acatcttcga atcatagcag gagctgggag cggcaaaacg caaacaatct
     4981 gtgcaaaagc tgtttatctg atgacgcaaa aacaagtaga cgaagaacgc atactaatga
     5041 tcacttttac aaggaacgct gcaaatgaac taaaaaaacg agtagataat ttcagccaga
     5101 gaaaaaccgc tgtccatatc ggaacattcc atagtatctt ttttaggata tacaatgaaa
     5161 tttgtcgaaa atttcctgaa gtagcaatgc aaggaataca aggagacttt tcaaaggata
     5221 ctgcacaaaa agtgaatgct gttttgcaac agctgatacg taaatataat ctttatatat
     5281 ttgatcaata tggagaaaaa acgattgctt ctcggttaga ctattggcag aatatgaacc
     5341 tttcagtaga agaaatggtt cagttagtta aagaaaaata tgattccatt gataagaatg
     5401 cacgacagcc gatatcagaa cgactgtatg gattgctcac ggaactccaa gaacaaaaaa
     5461 gaagccagca attgctagag ttcaatgatg tactccaaaa tctgaaaagc gctttggaga
     5521 atgaggagat ccagcattat atcggccaaa aatatgatta tctattcatt gatgaatttc
     5581 aagatactaa tccacttcaa tgggaaatcg tgaaacggat gacaaaggaa aacaggatca
     5641 agttgattgt tgttggagat gatgatcaga gtatctatgg attcagagga tcagagccag
     5701 catacatcaa gaactttgaa aaagaatatc ctaccaaaac tcttttctta ttaactaatt
     5761 atcgttctcg ggcagctatt gtccaaggag caaatagatt gatcagctat aataaaaatg
     5821 atcggatacc aaaggcgatg attccagcac aaaaagaagc aggtgttatg gaagcctatt
     5881 tgttttctga tactaaagca gaaagtcagt ggctaatcaa acaaattcag acatttattc
     5941 aaaaaaatgg gaaatataag gaatcaatca tattataccg atcagcttca caaacgcagc
     6001 agcttgtcca atctctgctg aaaacgaata ttccttttgt actggaagca gatagtccat
     6061 atgaaggtat ctttggtatc aagtctttcc aacatttcta tcaaaaaatt gttcattggc
     6121 aaacagcact gaatctgcaa aagaaaaatc aggcctacca gcaattgctc cggcagctga
     6181 tggcagactg ctacctgaaa aaaagtgaat gcgatcaata cttttctcct aaatatcaaa
     6241 atatagccgt tgcagattat attttgtcga taagccccaa tttaaaatcg aaatctgcag
     6301 aaatccgaga gtttgaggaa gcgttgcgta aaacagacca gcatcaagaa atctattcgc
     6361 ttgttcaaag ctatcttcat ctgccacgta tagctaagga aatcgaccag agtgatcaag
     6421 aatggatacg agaagaagta aagcagcatg ctactttcag aagactccaa gccttatcgc
     6481 aagaaaccca agcgacagct aaagaattaa aaacccgctt gattgcttac agacaaggaa
     6541 aacttgatgc actatgtatc cagagcattc acaaaagtaa aggtcttagt taccgaaatg
     6601 tctttttgat tggttgtaac gaaggaagtt tgccttataa cggagcgaca gaaaagaaag
     6661 taatcgactt taatgaaata aaagcagaac cagtaacgac gatagaagaa gaacgaagac
     6721 tattttatgt tgcgatgact agagcaagaa atcgtctgta tctatgtgta cctcaaatga
     6781 aaaattcaag aaaattgaaa gtatcgagat ttatcaaaga aaccgggagt cgtgtgaaaa
     6841 aaggaaagtg atagaagaga gggtgtgaca gaagtggtca gtttcaagaa agaagaagga
     6901 atgtacgaaa attgcttctc aaatttttgt gaaatttcag cttattttcg aagaagctat
     6961 ttctggaaca cagtttattc ggaaaaggga ggtgtgacaa gaattttgtc acacctccct
     7021 tatttatttt gaaaatgaga atactattat caaaatagag aatatataga aaaattctca
     7081 ttattcaaac gtaaataatc agttattttg atttttttta tattttatta gctaataatt
     7141 ggtattttaa aagaaattac tgtagaattg gattataatt aaaaaagggt gagaaaatga
     7201 taaaagtata tacttcgcct agctgtactt cctgtagaaa agcaagagca tggttgcaag
     7261 cgaatcaact tgaatttgaa gagaagaata tttttgccga accgttaaca gaaagtgaga
     7321 tcaaaaagat cttggcagcg actgaaggag gagttcaaga tattatttcc actcggtcga
     7381 aaatttacga aaagctgggc atagatttta acgaattaac tttaaagcaa atgatcgtct
     7441 tattcaaaga atatccttca ttattgagac gacctatttt gattgatgaa aaaagaatac
     7501 taatcggatt taatgaagat gagatccggt catttgtccc tcgtgaaatt cgatgtgttg
     7561 ccagaaatct gatctattta caaaacaata acatcttaaa ttcataggga gggagccttc
     7621 gtggaagtga aagtctatgg atcagcgcac tgtgtaacaa gtctgaaggc gaaacaatgg
     7681 ttagaacacc atcaattgcc ttatcaattt gttgacttag aagaacgcga tctaagtaca
     7741 gaagaagcag aagaattatg cagttttgaa gaagtgcaag cagaacagct atttgcgact
     7801 tggtctgagg cttttcacaa cattgcgatt gacctttcct gtgtaggaaa aaaacaactg
     7861 atttttttat gcacacaaca taccaatctc ctcagacgtc ctttgattat tatcgatgaa
     7921 gttctattta ttggatacaa tgagcagttg atggaacagc ttatcttaaa taaatagact
     7981 ttaactgttt taatcaagtc actgagcatt tcatacagtt gtaacagtcg aacacttagc
     8041 atcaagcgtg ttatgtgttc tttttttgac tttatttttc tactatagag acatgctcaa
     8101 tttatgtggt caaaattcaa atctaggtgg ggatatagag ttaaaaatat attgacatgt
     8161 gtaaatttac atgatatatt catttctgtt gttttaagta gcaaagcaat aaaatagtat
     8221 tttaaaaaac atataaaata gttgttgaca tgttagaaat gacatgataa gataactgag
     8281 ttgttaaaaa agaaccactt gtgaagcttg attctatcga aaaaaacttc aaaaaagttc
     8341 ttgacaaata acaaatgata agttatgata aatgagttgc tgtaagattt cgaaaaacga
     8401 aatcaaaaaa acttttaaaa aagagttgac aattacttgt ctctctgata tgatataaaa
     8461 gttgctacgg cagccaaaaa cgaatcgggg aacactcctg atgaagtaga cctttgaaaa
     8521 ctgaacaaag taagacaaac caaatgtgta gggcgtcttg attcaattca agacaacaaa
     8581 ca
//
LOCUS       DAZULR010000079         8534 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.083, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000079 DAZULR010000000
VERSION     DAZULR010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.083"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(48..1514)
                     /locus_tag="ACG8ZV_002518"
     CDS             complement(48..1514)
                     /locus_tag="ACG8ZV_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HFS4997783.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
     gene            1901..2497
                     /locus_tag="ACG8ZV_002519"
     CDS             1901..2497
                     /locus_tag="ACG8ZV_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFS4997784.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
     gene            complement(2500..2982)
                     /locus_tag="ACG8ZV_002520"
     CDS             complement(2500..2982)
                     /locus_tag="ACG8ZV_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997785.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(3088..3285)
                     /locus_tag="ACG8ZV_002521"
     CDS             complement(3088..3285)
                     /locus_tag="ACG8ZV_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997786.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            3580..4338
                     /locus_tag="ACG8ZV_002522"
     CDS             3580..4338
                     /locus_tag="ACG8ZV_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HFS4997787.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            4398..4826
                     /locus_tag="ACG8ZV_002523"
     CDS             4398..4826
                     /locus_tag="ACG8ZV_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997788.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            4872..4944
                     /locus_tag="ACG8ZV_002524"
     tRNA            4872..4944
                     /locus_tag="ACG8ZV_002524"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4905..4907,aa:Gln,seq:ctg)
     gene            complement(5094..5465)
                     /locus_tag="ACG8ZV_002525"
     CDS             complement(5094..5465)
                     /locus_tag="ACG8ZV_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFS4997789.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            5680..5865
                     /locus_tag="ACG8ZV_002526"
     CDS             5680..5865
                     /locus_tag="ACG8ZV_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997790.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            complement(5948..6136)
                     /locus_tag="ACG8ZV_002527"
     CDS             complement(5948..6136)
                     /locus_tag="ACG8ZV_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997791.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(6160..6423)
                     /locus_tag="ACG8ZV_002528"
     CDS             complement(6160..6423)
                     /locus_tag="ACG8ZV_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997792.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            6581..6838
                     /locus_tag="ACG8ZV_002529"
     CDS             6581..6838
                     /locus_tag="ACG8ZV_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HFS4997793.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            complement(6909..7100)
                     /locus_tag="ACG8ZV_002530"
     CDS             complement(6909..7100)
                     /locus_tag="ACG8ZV_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997794.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(7241..7561)
                     /locus_tag="ACG8ZV_002531"
     CDS             complement(7241..7561)
                     /locus_tag="ACG8ZV_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997795.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            complement(7584..8018)
                     /locus_tag="ACG8ZV_002532"
     CDS             complement(7584..8018)
                     /locus_tag="ACG8ZV_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFS4997796.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            8353..>8534
                     /locus_tag="ACG8ZV_002533"
     CDS             8353..>8534
                     /locus_tag="ACG8ZV_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFS4997797.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNS"
BASE COUNT         2701 a         1686 c         1353 g         2794 t
ORIGIN      
        1 aacaggaact gctgcaaata agcaattcct gtttttatgt tcattgatta atgaatagag
       61 cccattagtt ttttgattgg ttctttcaca gtaaatagca agataccacc gacgattgct
      121 actgcaccga taataccgaa gtaagcagat tctgttcccg gtgtgtagaa gcgtgcaatt
      181 tgtgcattga ttgcttgtga agaagcatca gctaagaacc aaatagcgat tgtttgtgat
      241 tcaaatgctc gtggtgctaa ttttgttgtc acagacaaac caactggtga aagacacaat
      301 tcagcaataa ccacgatgaa gaaacttccc aacaaccaca atggacttac ttttccactt
      361 gtaccataaa gcatacccgg caacatcaat agcaagtacg ataatcctgc aaataaaagt
      421 ccaagagaga atttcactac tgtagatggt tgacgttcac caagtttcgt ccacatcgtt
      481 acgaatactg gtgtcagaat aaagatgaaa attggattca atgattgata ccagcttgct
      541 tggatcgtta caccaaatag cgtagattgt gtacgttcac tagcaaataa agctaagata
      601 gatgaacctt gttcttgtaa tgaccagaaa atgattgctg caaggaataa tgggatataa
      661 gcccatactc ttggtttttc ttcagcagtt acatcttttg aagtcagcat tttgataaag
      721 taatacaacg gtaagataat ccccaataca ctgattgtat tgacaaaaaa gtcaattgtc
      781 agatgaccag ttagttgtgc cccgccgaat actgcagcga taacaacaag tgcgatgatc
      841 aagttacgga tgaatccttt acgttcttca gttgtcaaag gattcggcgg tgttgtaccc
      901 actccgtcta atgtcttgcg tccttggatg atgtattgta ataatccaaa gaacatccca
      961 atagcagcta aagagaaccc taaatgatag ttatattctt gaccgattgt accaacgatt
     1021 agtggtgcta ataatgcccc taagttgaca cccatgtaaa aaatcgaaaa tcctgcatct
     1081 cttcgcaagt cagtctttga ataaagatgt ccgaccatgc cagaaacatt tggtttcaaa
     1141 aaggcggttc cgataataat caatgccatc gaaacaaaca atgtacttac accaaatggt
     1201 aaagccaaga cgatgtggcc aagcataatg aaaactccac cgaagaatac agtgcgtttt
     1261 gctcctaaca ctcggtcaga tacccatccg ccgacgatac tagacatgta gatcaaagat
     1321 ccgtagatcg acatgatagc taatgctgtt gctcgtggta atccaagtcc cccgttggca
     1381 actgtatcgt acatataata gataagtaat gcacgcatac cgtaataact aaatcgttcc
     1441 cacatctcag tgaagaacaa agttgacaat cccttcggct gcccgaagaa gcccttgtct
     1501 tgctgttttt ccataatcta taccccaatt ctttaaattt tcagaaaata ttatacatct
     1561 ttaccgaaaa atttaactaa aaaacttatt taagaaatat aaactaattt tctataaaag
     1621 caagtaattt ttaatggcaa tatcataaaa aaaagaagat agagatttaa taattatata
     1681 tcagctgttt ttttcaaata agcaaaaatt cctaaaacac aacaatgaaa gcgataacta
     1741 agaaaatcct tacataacga tttttcttat taaaattgtt ttttgaactt cgcttatttt
     1801 ttgtgagcat atctgtttac ttactttttg taaggtgcta tacttcattt cgtaatcaat
     1861 taaaaaaatg caaaacgcaa atcaaaggag aaattttatt atgacaactt ttactgacac
     1921 tttgaaaaac cgccgttcaa tctatcatct aggacgtaat gtttcacttt ctaatgaaga
     1981 attaacaact ttgatcaaag aagcaattaa agaaagccca actgctttca atgctcaatc
     2041 aacacgcgca gttatccttt tcggagatgc acatgaaaaa ctttgggaaa tcactgaaga
     2101 agcacttcgc ccattgactc cagcagaagc tttcccaaat acacaaaaca aattagctgg
     2161 tttcaaaaat ggttatggta cagtattatt cttcaaagat actgacgtgg taaaaggtct
     2221 acaagaacaa tttgaattat atgcagacaa cttcccagat tggtcagaac aatcaaacgg
     2281 aatcgcaaca gctaatactt gggtagcatt agttgataaa ggattgggcg caaacttgca
     2341 acattacaac ccagttattg acgaagcagt tgcaaaagaa tggaatatcc cttcaaactg
     2401 gaaactacgt tcgcaattag tattcggttc accagaaaca ccggctgggg aaaaagaata
     2461 catgaacgat gccgatcgct tccgcgtatt tggataattt tattctggat caatcataat
     2521 atcaatctct gcctcatcgt ttaagcgttg ggacaaaaat ggaactaatt cttctaatga
     2581 tgcagaaaat ttcagcatcg gtcctcgcca tccgtttcgg aaaaaattca tttttacgat
     2641 tttagaacct tttggctgat ataatacaat tttattgatc tcagaaaaag gaacaccttt
     2701 tttgtcaaag ctattcaaaa caagtccttc ttctgtgatt cctctactgt ccaacaaaaa
     2761 actaataaaa atcattgctg acaagatccc ttttgccaat tcatctgctg taggatgact
     2821 gatgagtgta taccaaatga ctagtgacac taagaagggt atcaccaagt agacccatcg
     2881 atttcgcaca gtccgataaa taatttcttt tcgaaccagc caaagaaata aaaacatcac
     2941 aacaacgaat aaaaacaata gaaccgtaaa gaatgttacc atgacaactc gcctcgcttt
     3001 ttcttctcca gaaaatagga aaagaatact gatttacctt ctcaaagaaa ttggacttgc
     3061 agcacgccgc acgtccaatt gttttcttta ttcaaatgta tcatattttg caacaaccat
     3121 gcttgctttt tcatctaata attcttggtc ctctgcagca cattgggcaa ctttgaccac
     3181 ggcgcagttt gtcatttttg atacaacttc accaatgacc gtttttgtaa aaccaattgg
     3241 tttgcatgca tattgttctc ctaaattaat catttcttcc gtcatcaaaa tcctcctaaa
     3301 ctgctggaac ttttctccac attaccactg ctatttcttt ggagatttaa ctcattgatt
     3361 tttatttaca gttaaaaatc aaccttacag gcattatagc gtactgtttt cgttttcaca
     3421 attaaaacag ctgttgtatt tagaagaatt tttttcaaaa aattaaaaca tattccttaa
     3481 aaactaatta tttcctacat attaaaatat aatacttcca tttccaataa aaatacattt
     3541 ataataggaa agataaacag ctgaaaaggg agatttcaaa tgaagaaaaa aacgttcaaa
     3601 aaactattgt ttctaggggg cacagctgct cttttattaa gcggtacaag ttattaccta
     3661 catatccatt ctccagaaca tacaatgaac actgcacaaa aaagttcaac acaaaaaacg
     3721 aaaaagacaa aagagaaagc agaagtttta ctagatgttc cattagagag ccagtttgat
     3781 tctccttctt tagaaaatgg ctgtgaagtc acttcgcttt ctatgctttt atctttttat
     3841 ggttatgaaa caactaaaaa ccagttagct gagcaattgg attacgtccc tgttttcaat
     3901 gcagatggga ctcatggcga tcctaatgaa ggatttgttg gtgatatcag tggcggagac
     3961 tgggctatgg tcgtctatgt tcccccagtt gcctcccttg ctcagcaaat cgtccaaacg
     4021 gattatcaca cttttccaaa aaccgatgct caactcgatg atatcaaaaa agcactatct
     4081 aaaggaaatc ctgtctggac ttctgtgact atcaattttg aagtcccaga tgaaactgat
     4141 tttatgactt ggaccacaaa taatggagaa gtaagagtca ctcctcttgt tcatgcttgt
     4201 gtagtcactg gatatgacaa agaaaatatt tatgtcaacg atccctatgg tgtaaaaaat
     4261 cgagcagtac cgatcaacga tttttcggcg attttcactg caatgggtgg acagatgcta
     4321 actttggaga aaagctagta attcaaacaa aaatccctta tactcaagat accaaacctt
     4381 tgaagggagc gtagataatg gaaaaattca cacataaaaa aatggatcca aatgaaattc
     4441 cgattatttt tgtccgtgac tgcaagggaa atgttcaagg taaagtctct attaatgagt
     4501 ggaacgagcg tcgcagacct gctaccctca atgaactgga aatcaaattg tatcgtcaat
     4561 ctcttgttta ttacgcagat caagagtacg agaaagccac cgatttattg aaatttctaa
     4621 ttgctcgaac agagtatact cgctttgaat atattgaacg tttagcaaac atctatcata
     4681 ttatgaatga acctgtcaaa gaatatcagt tattggacac cgtcttgtca gtagcagaac
     4741 tgattgccct tcctgctgga ttagaaaaga aactagtacg ccgcctttta cgagtaaagc
     4801 aacaactatc cgatcaagaa aaataacttg cgttttttta ggaaagtgct atgattattt
     4861 tgttgaataa atgggatgta gccaaactgg taaggcactt gactctgaat caagcaattg
     4921 taggttcgaa ccctgccatc ccaatttgat gtgcttgctg aaaaaatgaa ccccctgtaa
     4981 aagaacaatc tttttgcagg gggattattg tattattttt actacttgta tttagtttac
     5041 ataattaaat tatgaataat aaaatcgggc gtattcttaa tacaaaaact gatttaccca
     5101 ataattgcta atgctttctc cggaactttt tctctaggaa cttcctcata cgtttctatg
     5161 tgtgctcctt tattgctaat tttcaaataa tgattttctt ttaacacaga aagaccatta
     5221 aattcaaccg ttcgttcttt cccattggca tcagcagctt tctgcacata ccttgctgta
     5281 ccatattcat ttacttcctc tggtttttgt gtctttacat agacctctcc tttttcaact
     5341 aatggattta gctgatcaag tataccaggg atttctccat aacttccttc agtataatat
     5401 ttcagtccaa atagcaaaat accactaatc gccgccagtc caatcaaata tttaatcact
     5461 ttcatctttc tacctccttg ttatatattc agtatatggg tcagttaaag aaattccatc
     5521 cgtcccaagt tggagatttt tctcctactt tagaagcgag aatcgagtgt ttttttagta
     5581 aaaatgatcg ttatttgata ttattgacgt gtggataaat cagtttttct cgttttgtcc
     5641 atgtaaaaaa tcatgttgat agcaaaggat gtgttcaaaa tgaatcaaga agaattattt
     5701 caaaaagtca aggaaatgat taagaacggc aatttcgatg gcgcaaaacg atttatcgaa
     5761 gaacataaag aacaattagg accttataaa gagaaagccc aaaatctttt aaaagatgta
     5821 aatatcgaca gtgtcaaaaa caaatttaaa aatctattca aataagtaaa actttcactt
     5881 ttgtaaaatc aaaggaggac aatgctgctg catcgtcctc ctttggttct tttctgaata
     5941 cttcatacta aaataaacgt gtcggatcgt aatgataagt cacattgccg ttcagtgagg
     6001 cttttcccac cacatattta cgattctcca acttcagcca cgcttctcga aaagccatta
     6061 attcttctct ttttacatca atcttttcga tttttccatc gatcaaatct tgaataagtt
     6121 gttcatatgg attcattttt ttcctccatc tgctgtcaat caataagttg taaaaatagg
     6181 ttcatatgct tttttggtat ctagatcttc tctgactttg actgtcgtat aaataatttt
     6241 ttctactggg atactataat aacttccttc accattattg aatcggtgaa cgtctttctt
     6301 tgctaaaata ccatttattt tattcgtcag tacacgttgt tcgacactgt tacttacaac
     6361 atagtaaatc acccgaatat tattgatcaa atgcaaatcg atttctaaca ctacatgatc
     6421 catgaaaatc ccactccttc tttcactttg attatagcaa gtttctcctc taatttcaaa
     6481 atcgatacag attttaccgg ataaatccac aaaactgctt gcgccatttc gcacaaagtg
     6541 ttattttgta tcatggactt tatttatcgg aggcaatagt atgatcgcga tcggtcaatt
     6601 tgttttttat attccttttt ttattatgat aagcattctt ttctattaca taaaatggac
     6661 aaaaaagaag ttttcagttt tactggcctc tttacctgct gtatatttta cttatcaaat
     6721 tttttctttt aggcattggg aaacaacgtc tgtattaata acacacatca tcgaattgac
     6781 gctttcagta atttttctta ttatttggat ctatttttta tataagaatc agaattgaat
     6841 ccctcgcatg tttaaaaaga aaacgattaa agatgcagca aatttctgcc gatctttaat
     6901 cgttttttct attctgttat accaaaaaaa tgtttgaatc ggtgaaggat cgttccttgt
     6961 tttaattcta taaattcttg tgcgatcggg tacttttctt ccaaattttc tttgttcttt
     7021 tcgatcaggc ttttcgcttc ttcatatttt ttatctgcac atagtgcttt tacttcctgt
     7081 aatacttttc ctgcttccat ttgcctcacc ctcttgccat tttattgctt taagttttat
     7141 ttaagttata cgcattattc tagtttcatc ccaaataacc ttttttcatt tttactcctc
     7201 gaactaatca gttttctaaa ggctgattgg ttcgtctttt ttatttttcc tccatttcat
     7261 tctgctcttc tgttaattta tctaatgctt tgattgatgc tgcggctctt gcataatcat
     7321 agctgtataa ttccataaat ttatcaggca gaacaaacca cgctggatga taaccgttag
     7381 ctgtgacagg gaatccttta tcttgttggt tatctccatc ccatctcaga gcaacacctt
     7441 tttttccttt ccactttact aaagcgatcg agtatccctt ctttgtttgt gtgccgtctt
     7501 caataattgc taaaatttct attttttctt ttggcgcacg gacttcttga ggacgaacca
     7561 ttttctattc ctcccttatc tcattacttc acgaccaaca cactgcaagg ggcatgtgat
     7621 acgacataag aagcggtcga tccaactaat gcttgttgta tagcaccttt tcctgtcgct
     7681 cccataacga tcaaatcaat attttcttgt ccagggatga cattggcaat caaatttctt
     7741 ggatctccag tttcaactat tgcgtggatc tcagcaatgc cgtactcttt ggcatcattg
     7801 atttttttca gcatggctac ttctgttctt tgtttttcat ctgcatagat ttttgaaaag
     7861 gcataggcac tatgggtcag ctcaactttg ttgatgattg acacgataaa taagtgggct
     7921 tcattgtcct ttgctaagtc aagggcttca gcgaacgctt tgatcgattg tcttgatccg
     7981 tcaactgcta ccatgatgtt ctggtatctt ttactcattg gaaccgcctc ctttttcttt
     8041 tattgtaaca tctcaagcaa aaatacaaaa aatatacgca atatgtaaat aaaatgatga
     8101 acaaaagcaa tttctttcaa gttatttata catttctttt ctcatcagaa cacctgttct
     8161 aatcccatta tttctgcatt atgtgaaatt cctcatcatt tttcacatcg agcgaacatc
     8221 attctgttac aaaaaacgtg gatttgtcat aaattgtcat gcttctttta cctatgaaat
     8281 attttcacgt gttaaagtat tcctcgttga acacaacaaa taaaactttt taacgaataa
     8341 aggagatttt tcatgacatc acttaaaact ttactttttg gaacaacttt ggctgccggc
     8401 gctgcattct tcatgggaac gactgctcat gcggacgaag cttataccgt tcaatcaggt
     8461 gatactctat caacgatttc tcaaaaatac gttggtgata actccttgat caatgccatt
     8521 gcagaatcaa attc
//
LOCUS       DAZULR010000080         8415 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.084, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000080 DAZULR010000000
VERSION     DAZULR010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.084"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            328..1251
                     /gene="truB"
                     /locus_tag="ACG8ZV_002534"
     CDS             328..1251
                     /gene="truB"
                     /locus_tag="ACG8ZV_002534"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HFS4997798.1"
                     /translation="MDGLLTLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEEKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVKRFKRVDITDEVWQKVKNGMRLNYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            1255..2196
                     /gene="ribF"
                     /locus_tag="ACG8ZV_002535"
     CDS             1255..2196
                     /gene="ribF"
                     /locus_tag="ACG8ZV_002535"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006747 - FAD biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009398 - FMN biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HFS4997799.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGEIWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            2591..3376
                     /locus_tag="ACG8ZV_002536"
     CDS             2591..3376
                     /locus_tag="ACG8ZV_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFS4997800.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWINNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENDKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            3389..4240
                     /locus_tag="ACG8ZV_002537"
     CDS             3389..4240
                     /locus_tag="ACG8ZV_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HFS4997801.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(4364..4816)
                     /locus_tag="ACG8ZV_002538"
     CDS             complement(4364..4816)
                     /locus_tag="ACG8ZV_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4997802.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQIREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNHVVNFSQWINEKLLMQTDISLVS"
     gene            complement(5281..5649)
                     /locus_tag="ACG8ZV_002539"
     CDS             complement(5281..5649)
                     /locus_tag="ACG8ZV_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HFS4997803.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            5799..6281
                     /locus_tag="ACG8ZV_002540"
     CDS             5799..6281
                     /locus_tag="ACG8ZV_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HFS4997804.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            6318..7328
                     /locus_tag="ACG8ZV_002541"
     CDS             6318..7328
                     /locus_tag="ACG8ZV_002541"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S66 peptidase family protein"
                     /protein_id="HFS4997805.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPPWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQPSEKYQKEWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTISHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(7443..8156)
                     /locus_tag="ACG8ZV_002542"
     CDS             complement(7443..8156)
                     /locus_tag="ACG8ZV_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997806.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIKQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLINVIVMDN"
     gene            8306..>8415
                     /locus_tag="ACG8ZV_002543"
     CDS             8306..>8415
                     /locus_tag="ACG8ZV_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFS4997807.1"
                     /translation="MSKRTRRTFSQEFKQQIVNLYLAGKPRVEIIREYELT"
BASE COUNT         2861 a         1366 c         1702 g         2486 t
ORIGIN      
        1 ttaagaaact gaaaaaataa ataaaaaaaa acggaaaaaa gactggaaga atggacagtc
       61 ttttttttcg tttttgggaa gtgaaaacca aactatttac ctgtaagcca cccataaatc
      121 caatcaaatg gtgcaaagaa aaaatcttcc attctattcc ctcctttaaa aaaaacataa
      181 catgatttct atttacgtga gcatgaattt tgttacgttt ttattgccga aaaataaaaa
      241 ccgttcatta tgatgtcaaa ttcgtcagta attgatgcaa tgtgttataa taattcagtt
      301 aaatcaaaaa tgaaatggag aaaagacatg gacgggttat taactttatg gaaagaacgc
      361 ggaatgacaa gtcatgattg cgtattcaaa ttaagaaaaa tcttacatac gaaaaaaatc
      421 ggacatgggg gtacgcttga cccagacgta gacggtgtgt tgcccatttg tattggaaaa
      481 gccacaaaag ttatcgaata tttgacagat tctgggaaaa tctatgtagg cgagataact
      541 ctaggtttca gtacaacgac ggaagatcga tccggagaac gggtagaaac aaaaccagta
      601 gatatgtctt tatctgaaga aaaaatagat gaagtgatgg cttcatttat tggtgagatc
      661 acccagatac caccaatgta ctcagcggta aaagtcaacg gtaagcggtt atatgaatat
      721 gcccgcaata atgaaacagt ggagcgtcct gttagaaagg ctcagattta ccgttttatc
      781 cggacaagtg aattgacaag agacgaagtg acaggaacca tttcttggcg cttcgaagta
      841 gaatgcggga aaggaaccta tgtccgcaca ttagctgtag atacaggcaa gaaacttggt
      901 taccctgcgc acatgtctga tctgacccga acagcaagtg ccggtatgtc ccagaaagat
      961 gctctgacat tagaagaagt agctcaagct gtgaaaaatg ggacaatcga tgattgtttg
     1021 ctgccaatag aaaaaggagt gaaacgattc aaacgagtag atattactga tgaagtatgg
     1081 cagaaagtaa aaaacggtat gagacttaat tatactgtat ttgcgctccc agaaatgccg
     1141 tcagaagaaa ttgctttgtt ttataaaggc aaagttgtca gtatctatca gccaaacccg
     1201 aaagaaaaaa acaaattaaa acctagtaaa gtattgagaa atgaggaata acgaatgaat
     1261 atcatcaaga tcagacatcc ttaccaatca gaacaaattc cagaagacga tgtcgtttta
     1321 gtactaggat tttttgacgg cgtgcatatt ggacaccaga aagtcataaa gacaggtatg
     1381 gaaattgcac aaaaagaagg attgaaatta gcattgatga ctttcaatca gcatccatcg
     1441 attgtcttta aaaagatcga tcctagcagc gtgaaatatt tgactagcct taagcaaaaa
     1501 gaagaaaaaa tggccgcttt gggtatagat tatttatatg aagttgattt tacttcttct
     1561 tttgctcatt tagcaccgca ggaatttgtt gatcaataca tcgtagggtt acatgcaaaa
     1621 tatgctgttt ccggttttga ttatacgtat ggaccaaaag acattgcaga tgtcgctcat
     1681 tttcctgaat atgccaaagg aagattcaaa atcgtcacag tttctaaaga agaagaacaa
     1741 ggtgaaaaaa tcagctctac ccgtattcga ggattactag acagcggaca agtaaaagaa
     1801 gcagcaaaac tattaggttg cacatatgag gtagaagggg tagttgtcca tggcgatgca
     1861 cgaggcagac tactaggatt ccctacagca aatgtcaaag taaagagcac agttcatttg
     1921 cctaaagaag gtgtttatgt atcggaaata aaaattgggg aaatttggta tccagccatg
     1981 ggttcaattg gacataatga tacattcggt gaaggacggg agctgactgt agaattgtat
     2041 attttggact ttaatcaaga tatctatggt gaacatgtcg cagtacgctg gaatcaattt
     2101 ttaagagatc aagtgaaatt ttctagtgta gaggaattga ttgaacaact caaagaggat
     2161 gaacaagcaa cagctgaata tttttctcag caataaaaca ttatgcataa aatctcttgt
     2221 ttatgtataa ctagcaattt caataaaatg ggtgataaat aagcccagga aaggggctgt
     2281 gacaaaagtc ttgtcacagc ctttttttcc aaataaatgg tttttcagaa gtagcttctt
     2341 cggaaataag ccgaaatttc acaaaaattt gagaagtaat ttttgtaaat tacttcttat
     2401 ttcttgaagc tggccacttc tgtcacaacc tctttcttta tagaaataaa aggacactag
     2461 caattcatga aaacgattgc taaagcgtat catttgcttt agactatata tcttggtgta
     2521 cactcacttt aagacggaaa taaaagttat ccgtaataac aggtttaggt atgaaaaagg
     2581 agtgggtact atgtataagg aattagaaaa caaagtcgca gtagtaactg gtggctcaaa
     2641 ggggattgga acagcgattg ctcaacgatt cgggaaagaa aaaatgaatg tagttgtcaa
     2701 ctataactcg gataaagaag gagcagaaaa agcagtcaaa gcaatcgaag aggcaggcgg
     2761 aaaagcagtc tctgtacaag cagatgtcag ttctgaagaa ggaatacagc gtttacttga
     2821 tacggcttta gaaaattttg ggacactgga cgtttggatt aataatgctg ggatggaaaa
     2881 tcagcatcca acccatgaac ttagccttga agattgggaa agagtattaa aagtcaattt
     2941 gactggcgtt tttatcggaa cgaaagcggc tttaaattac tttacagaga atgataaaaa
     3001 aggaaatatc atcaatatgt cttctgttca tgaacaaatc ccatggccaa cgtttgctca
     3061 ttacgctgct tcaaaaggcg gagtaaaact attcaccgaa acggtagcaa tggagtacgc
     3121 accaaaggga atcagaatca atagtatagg acctggtgct atccgtacac ctattaatgc
     3181 ggcaaaattt gatgatcctg aacaaaaaga actcttggaa agtatgatcc cactaggacg
     3241 cgtaggtgaa ccaaaagaaa tagcggcgac agctgcatgg ttggcttcag acgaatccag
     3301 ttatgttaca ggtattacac tatttgcaga tggtgggatg actttatatc cttctttcca
     3361 aggtggaaaa ggataagggt gaataaaaat gggtttattg attgcattga tcccggcagt
     3421 tgggtggggg atccagccac tgattttgaa aaagattggt ggcagaccaa caaatgagat
     3481 attaggaact ggtattggag ccgtgctcgt tggcttactt gttcaattat tcgcttctcc
     3541 agctggtatt tcagtgacta catttttgat tagtttactt tctggtgcat tctgggtcat
     3601 cggacaaaca ggacagtata catctttcaa cttgattggt gtttctaaaa cgatgccaat
     3661 ttcgactgca ttacagttag tcggaacctc attgattggt gtcttcgctt ttggagaatg
     3721 gtctggaagt atgggaaaaa tcattggtgc agcagcaatc attcttcttg tatttggttc
     3781 tgctttaacg gcaatcagtg atgatcctgg aaaaaaaggc ggtatcacaa aaggaatcag
     3841 tctattagca tcaacaagta ttggttattg ggtttacagt gcattgccca aactagttga
     3901 tgcaagcgga ctttccattt tctttccgca aatgatcggt gtctttttag gggcagtgat
     3961 ttatgtgatt ttccgaaaac caaccgcatt ttctgaagac aagagttgga aagcaacaat
     4021 agttggagcc atcttcagtg tgtcagcatt ggcttatatt ttttcagcaa atgaaaatgg
     4081 ggttgctact gcatatatca ttacacagct aaacgtagtt atctctacat taggcggtat
     4141 gtacatcctg catgaaaata agacaccaaa agaaaaaaaa ttaacgatta tcggattatt
     4201 gctgatcgta gtaggaagca tggtcacggt ctttatttga ggataaagat ggtaaaatct
     4261 catttattaa aaaaatattt gtttgaacca aacagtaagt acttataaaa aaatagcgct
     4321 agaatttcca acatctctgg aatttctagc gctttttaat tgtttaagat acaagtgaaa
     4381 tatctgtctg catcaataat ttttcattga tccattgact aaaatttacg acatgattga
     4441 agttaccacc gattagtatc tccgcatgat tgtctttata aagatcgtat tgtaaaagac
     4501 ggtctttttt atttgcgtaa acatcgttat ggtactggac taattgttct cggatttgat
     4561 tgattgctgt aaaatcacga tactgaaggt tgaaacgcat cgtgattggt gcatttagca
     4621 tgaatcgctg catttctttt gctgcttcct ctgcttgatc tccgtatagg aactcaaaaa
     4681 gattacgttc agaaaatttc cattgcccgc caacctttgt tccttttagt tttccttcat
     4741 gaagataatt tctgatagaa cgtgtagtaa cacctaattg ttcggctaat tcatttactg
     4801 agtaaaaatc tttcaatgtt caccctccta tgtgaatggt tctactgact tagttgatat
     4861 ttgcttaatc acgaaatgta gaaagaacga ttttaattaa ggtcattgta aaaatcaagt
     4921 cagaaaattc taacttttct ttctctaaag aaattcgttc tctcctaaag tgatattata
     4981 tttaaatata cctgaaaata atgggcagta ttatgaaaga tcactgatat tttctcgtat
     5041 tttttcctta ttcaaaagtt ttgcaggaaa attgctgaaa aaataatttt actaagtgga
     5101 aaattcaaag ccattcaatc agtgattttt ttcagcacaa gaaagactcc ttataaaaat
     5161 agcagatact ttgtcaatta agtgtttaac cagggatgat aaaaaggata ggattgaaca
     5221 aaacctgtat aagctgatga atagtttcct cgccagtaaa aggtttattc gtataaagct
     5281 ttatcgccaa aatttatcat gacctttttt atcttcaata ttaaatgaaa tcaattgttc
     5341 aatcaattcc cagttgatta cacttttcca aggaactttg atgacgttat ccgtatatac
     5401 gtagcctgct tcttggatat ttttttcaag ggcacgaatc gctgcttttt ccggtgcgat
     5461 agaaaaatga tttttagcaa aactaaatgc aataataaag gtaccatggt cagtaaacat
     5521 aggttggttc cattttacag ttgtgtctag ctggggatac gtttctgtta tcttagcaaa
     5581 aaggtctttg atcttttgtt gatgttcttt ttctttgatc tgattgatga tcggctgaaa
     5641 tttttccatt ctaaaacgcc tccattaagt ggtttgattt attttaccag aaaaacaata
     5701 gttatgtata aaaaacgaac aaaacacaag taatgttgta accgctatat ttatatgata
     5761 agatgtctca aataataaaa tagaaaagag acataaaaat gattgacttg gcaaagaaat
     5821 tcttacacga aaatatatat tttgagttgt atcatcatcg agccatttat acaaatgaag
     5881 atgctttggt aataaagaaa gaacaaggat ttacaggtac agagaccaaa agcttattct
     5941 taaaagataa aaaagataat aactacgtat atctgacttt tactacgaaa caaacggatt
     6001 tcaaagcatt agggaagatc gtcggtaaaa ggctttctat tgtttcatca gaacgcatgg
     6061 aagaacaaac gggacaaaag cagggcgctg tttctccgtt tggttatgaa aaacagattc
     6121 cgattattat tgatgaagag ctcttatcaa atgaaaaact tgtttttgca ccaggtagac
     6181 cagatcaaac gatggtcatc caaacggttg acttaaacaa aatcatccag ctacttgaga
     6241 tgccgatatt tttgatgccg gcaaacgaaa aaaacaatta accaagtaaa atagtgcata
     6301 cttggaggtg aagcaacatg ataagttatc cattattaga aagaaatgca acgattgggg
     6361 ttactgcacc atcctcaggc gtatcagagg aacaccattc gttactcgaa tcagctttaa
     6421 agagaatgga agaaaaatct ttccaagtag ttactggaaa gacgctttgg acgcaagata
     6481 aggaaaaatc aggtccagca agaaaacgag cagatgaatt caatcaaatg atgcaagatg
     6541 aaaatatcca aatgatcttt ccgccttggg gaggagaatt attgattgag attctcgatt
     6601 ttgtcgattt tgatgctcta caaccaaaat ggatagtagg ttattcagat attagtacgt
     6661 tgctacttgc tgtcacatta aaaacaggga tagccactgc acatggaacc aaccttattg
     6721 atttaagagg agagtacttg gatgaaacga cagcaatgtg ggaaagtgta ctgaaaacaa
     6781 gagaaggaga atcgattcta cagcaacctt ctgaaaagta tcaaaaagag tggccccatg
     6841 agcattcatc atcttctgtt ttccatctca ctgaaccaac aaattggcaa tcagtcagcg
     6901 gagatgcagt aaggatgaag ggacgattat taggtggctg tattgatacg atcagtcatt
     6961 taatcggtac cccttatgga gatgtccaat cttttaaaag aaagtataat gatggaaagc
     7021 cgatcttgtg gtttctagaa aattgtgagc tatcgtcagt tgatttaaga agatcacttg
     7081 ttcagatgaa actggcagga tggtttgatg gcagctcggg gatcatgttc ggtagaagtg
     7141 cagcagagga tttgttagat tataaaatga aggatgtata tgaagatctg tcaaaggaat
     7201 taaaactacc gatcttgtat gatattgatt gtggtcatgt accgccacaa ctgacattga
     7261 tcaatggtgc ctatgcagaa gtagcggtag aagatagaaa agcgactgtt ttgcaaacgt
     7321 ttatttaaaa aattttttcc tgccttggag tttatcaaag accaacaaat ctaaatagaa
     7381 aagaaaatga aagaagctga cagtattttg ccagcttctt tttgtatgat ctattagaaa
     7441 ttttaattat ccataactat cacattgatc agctgtttca catcatttgg attacctgta
     7501 ggaatagcta ctacagatgc attatcaata atttcttgag ttgtttctct aatgaacgct
     7561 ggataagatg tttgatctgc aggcatttgc caatgtgaag gaactggata actagtgatt
     7621 gtcccgtcat ggttacttga atacactaaa actccctggt aactgtattt cccagtgagc
     7681 ataaccacat ctttcggata gactgcactc cctgcatcat aaggggcgat aggtgttcct
     7741 gcaggataat gaataacatg tagttcgaaa tcacccgatg tatctctaaa agtattacct
     7801 ctaattgcta gccaaacacg tgcgtactca atttgtagat cagaatatcc tgctaacgga
     7861 tctattgact gagaagactg tgaggaagtt gtgtctattg ttgaagaaga aatatttgtc
     7921 tcaactgtac tactagatgt agaagaagta ttgggctctg agactttact gcttgttgaa
     7981 gatgtattcg tttcagtaga agctgatttc tgagtacttg atttttcagc tgaactggtt
     8041 tgtttgattg aacttttgtc tgtggtcgca gatggatcac tattttcttt actaggagac
     8101 gtacatccta caaggaataa agagaccaac aataaaataa aacctaactt tttcatataa
     8161 aatacctcat tattttttta ataccagtat agcataatcc tgaatttttg aatccgtaaa
     8221 accttgtcta tggataggct acaattaact agacagaaaa attaaggtgt gtagactaga
     8281 agaaaacata ccaggaggaa tttttatgtc taagagaaca cgaagaactt tttcacaaga
     8341 attcaagcaa caaatcgtca atctttactt agctggaaag ccacgtgtag aaatcattcg
     8401 agaatatgaa ctaac
//
LOCUS       DAZULR010000081         8252 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.085, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000081 DAZULR010000000
VERSION     DAZULR010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8252
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.085"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            235..1560
                     /locus_tag="ACG8ZV_002544"
     CDS             235..1560
                     /locus_tag="ACG8ZV_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HFS4997808.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSMNLFTTEGTRSQRRKKLAQMIQENIKEELGLLA
                     TVGVGDNPLLAKLALDNEAKHNDGFLAEWTYQNVPDKVWNIPEMTDLWGIGSRMKKRL
                     NQIGIMSIKDLANWNPYTIKSHLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLYIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGAGGLKND"
     gene            1553..1903
                     /locus_tag="ACG8ZV_002545"
     CDS             1553..1903
                     /locus_tag="ACG8ZV_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997809.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEKIDADNEQRANQNLAKEQMTTE
                     EVAEVLNAAVIKNRSVCIQKEERNAEGYYPEDIVSKILGSDELGIYVGKNKVHYDEIR
                     HIEFYQDNKWGRLE"
     gene            1885..2070
                     /locus_tag="ACG8ZV_002546"
     CDS             1885..2070
                     /locus_tag="ACG8ZV_002546"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997810.1"
                     /translation="MGSIRMNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSF
                     YVEAAAGYHKYEYYIGY"
     gene            complement(2974..3249)
                     /gene="prgO"
                     /locus_tag="ACG8ZV_002547"
     CDS             complement(2974..3249)
                     /gene="prgO"
                     /locus_tag="ACG8ZV_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA segregation protein PrgO"
                     /protein_id="HFS4997811.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(3221..4174)
                     /locus_tag="ACG8ZV_002548"
     CDS             complement(3221..4174)
                     /locus_tag="ACG8ZV_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFS4997812.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            4786..6279
                     /locus_tag="ACG8ZV_002549"
     CDS             4786..6279
                     /locus_tag="ACG8ZV_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HFS4997813.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            6414..6710
                     /locus_tag="ACG8ZV_002550"
     CDS             6414..6710
                     /locus_tag="ACG8ZV_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HFS4997814.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
     gene            6811..7662
                     /locus_tag="ACG8ZV_002551"
     CDS             6811..7662
                     /locus_tag="ACG8ZV_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997815.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILD
                     LTVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAG
                     KLFKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILF
                     FVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKG
                     IRSILKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDL
                     ELPMKDK"
     gene            7683..7895
                     /locus_tag="ACG8ZV_002552"
     CDS             7683..7895
                     /locus_tag="ACG8ZV_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997816.1"
                     /translation="MIPLYRIVLIVGMELKTLKKEQLFKVKERHNQLLCSKTGTMNIE
                     YRTEYLELTNQTDFLLIRKQQEQEKN"
BASE COUNT         2866 a         1283 c         1553 g         2550 t
ORIGIN      
        1 atttttttct aatataacta agcaaaactg gataatacga cacttatttt caaattttca
       61 caagactaat agtaaatatc catttaataa agtgatacaa tgtgttgatt ttacaaatca
      121 acagaagaag tagggaaata acttacctat gcttcttttt ttgtacattt aatcgattct
      181 tctttacaaa aacgaacgta tgtttgtata atgtggaaga atggagtgtt atttatgatg
      241 gattattcaa aagagccagt aaatgattac tttttgatcg atatgaaaag cttttacgca
      301 agtgtcgaat gtatagaaag gaatttagat ccattaacga ctgaattagt cgtcatgagt
      361 cgagcggata atacaggatc agggttgatt ttagcttctt caccagctgc aaagaagaag
      421 tacggtattt ctaatgtcag tcgaccacga gatctaccgc aaccttttcc taaaacgtta
      481 catgtcgttc caccacgcat gaatctctat attaagcgaa atatgcaggt aaacaatatt
      541 ttcagaaggt atgtagcaga cgaagattta ttgatttact cgatcgatga atcgatctta
      601 aaagtgacca gatcaatgaa tctttttacg actgaaggaa caagaagtca acggagaaag
      661 aagctggctc aaatgatcca ggagaatatt aaagaagagc taggattgct tgctacagta
      721 ggtgtcggag ataatccctt attagctaaa cttgctttag acaatgaagc aaaacataat
      781 gatggattcc ttgctgaatg gacgtatcaa aatgttcctg ataaagtatg gaatattcct
      841 gaaatgacag acctttgggg tattggatct cgaatgaaaa aaagactcaa ccaaattggt
      901 atcatgagta ttaaagactt agctaattgg aatccataca ctattaagag ccatttaggt
      961 gtgattggct tacagctgta ttttcatgcg aacgggatcg atcgaacaga tatagcgatc
     1021 ccaccagaac cgacaaagga aaaatcatat ggtaattcac aagtgttacc acgagattat
     1081 accaggagaa atgaaatcga actggtggta aaagaaatgg cggaacaagt agctattcgt
     1141 atcaggcaac ataactgtaa aacaggttgt gtccatttat acattggcac gtcgatctta
     1201 gaaacgagac caggtttttc acaccagatg aagatcccta taacagataa tacaaaggaa
     1261 ttgcagaatt actgtctttt cttgtttgat aagtattatg aaggacaaga agtaaggcac
     1321 gttggaataa cctatagcaa gcttgtgtac actgattcgc ttcagctgga tttatttagt
     1381 gatccacaaa agcaaattga cgaagaaaat ttagataaaa ttattgacaa gattcggcaa
     1441 aaatatggtt ttacgtcgat tgtacatgct tcttctatgt tagaaggcgc tcgtagtatt
     1501 actagaagta cattggttgg tggccatgca ggcggcgcag gagggcttaa aaatgattga
     1561 ttataatgat cgtggacgtt taaagtgggc aggtttttat ttatctgatc atactgaaaa
     1621 aattgatgcc gacaatgaac aacgagccaa tcaaaatttg gcaaaagaac aaatgacgac
     1681 tgaagaggtt gcggaagtat tgaacgctgc agtcataaaa aatagatcag tatgtattca
     1741 aaaagaagaa cgaaacgctg aaggatacta tccagaagat attgttagca agatcttagg
     1801 tagtgatgag ctggggatct acgttggaaa aaacaaagtt cactacgacg aaatacgtca
     1861 tatcgaattt taccaggata ataaatgggg tcgattagaa tgaacattat ccagcaatat
     1921 gagctaaagt atataacctt tgatcagcta tcagaagaga tttggggtta tggccagcgt
     1981 ttgataaatg aggttggtgt tgaacgcttc tctttctatg tagaagctgc agcaggatac
     2041 cataaatacg aatactatat tggctattaa agtgcaataa aattatattt cttttatgtt
     2101 ttacattttg tatcaattct gataaaatta cctataggta attaaaaaat ataaaaaaac
     2161 tagttacaac cttaggacgt tgtaactagc ttgaagcata ctagagctaa ctaaaatagc
     2221 actagaaagc aatgttaaac ccgtccaaca aacttgattt aacattgaga ccagcttatt
     2281 cagctaaata tagttgaata agcttctttt gttttaaaaa aacaaaaggt gtactacgaa
     2341 taacgcaagt aaaagaaata ctattacaac cagtaggcta caagtaagta ttactaaaca
     2401 ttgcgtagtt agaacctttg ctctattgtc taaagccaca aaattagaga tcagctttat
     2461 gatgctaaga gcgagctgca tccatgcgga cataggttct tttgacacta ttaattctcc
     2521 tttttaggat aagggaaatt gctagtagtt ttttcattag caccatcccc cttcatttga
     2581 ttgagtctag tgctgctgtg atagtttgct gtttaatatg cttacattct tattataaca
     2641 taaatgaaac aaacacatgg ttagaggtcg tatcaatcaa aatagtgtct cacaaacgat
     2701 ttattactta ctcctgctga ctaacggact gttcttcagt aactgtaact atatgtttgt
     2761 taaaaccacc attacctgta gataaaaacc aatatattta ctatactcac tatattaaat
     2821 atatttagta tagtaaaaac tagaaacaat aaaatttgtg aatgttgtat acccccaaac
     2881 aatacacata ttttgaagga ttaggattaa taaagctaaa aatatagtaa gtatactaaa
     2941 tatatttact atatctagta tacttactat attttaatct tttgatcgtc tattatatat
     3001 aatccgttcc tcgtcgttta aagtatcaac ataggcgtcc attgcaagtt tgactatttc
     3061 atacatagga atatcttttg cataactaag atcccgaatg gtttttagta cgggaggatc
     3121 tacttgaact ggttttcttt ctttcgcagt gtactttcgt tcccctaact cgacattaat
     3181 atcatcttta attgaaatat cttcagcacc aattttcttc ttatctttgt tcgttggtaa
     3241 taatgccatt tagtttaatc tcctttccaa gaggtaggat atgattggcc attgagtcag
     3301 catatttagg tgtataatca aatccttcaa tatcaccatg ttgttcatag tattcaattc
     3361 tttcttctaa ttctgtaaag atgtctgcaa aaatagccca ccatcttcga tctacataat
     3421 catttaattg gataccattc tcaccataca tttctaaccg atccgagcct ttaacaatgc
     3481 ttttaaaaat gtttgattca ccatacttat caattgtttt ttgatagttt gcgtgttgag
     3541 aggaacgtcg cactgagaaa agaacaggca aaattccaat gatttgaaga tgagactctt
     3601 caaaattcgt gacaatcgga actaaaactt tattaataaa atcttctgtt ccttccattg
     3661 cgtaccgttt taattcttgc attgcaataa tataatctgc agcagttaag aatgcacgaa
     3721 ccacattatc tgttgatggt gggcagtcga taaagatata atcgaaattt tttctcaatt
     3781 cttctaaagg tttaatgaag gccaatgatc tcttacgacg atcaggatat ttttcggaca
     3841 agtattcatt aagttcttca gatccaggag agccagccat aatatataaa tgtggactta
     3901 cttgagtaat acctgaaacc cagtcccctt ttttgattgc tgcagacatg gatcgatcaa
     3961 agctagtaat ttgatacgtt gatccaatgt tggaagtagt atttctttgt tggtcataat
     4021 caattagcaa cacgtctttt tcaaaaagtt gactagaaac aatcgctaat aaatcattgt
     4081 ctgtagtctt accaatgccg ccttttctac ctgtaagcat tacaactttt cctagtttat
     4141 ctgatgtttt aaatgcagtc cgtaagtttt ccatagttcc ctccaatttc ctatactaaa
     4201 tatatttagt atacttcata tacttaatat attcgatata tctaatatac tccaaattga
     4261 taagaattca gactttataa ggaatatagt ggatatacta aatatatttg ctatattcag
     4321 tatatcagat atattcaaaa tgtcaaaata tatttgtgcg ttttgcgttg acaatttaga
     4381 gtgaaaagag gtaaacttaa ttctatagaa accacagata attcactatt tacaaagtag
     4441 caaaagcagt ggtactcttt aaacagaaaa attacataaa aaaaagagac ggaaataatt
     4501 gattttagca gaatcaatta tttctgaatc acatggttag gacatgtgtt cacgctcgtc
     4561 tcaagaatat gtaagtagct accaactact tatattaaaa gttgatcgga taccttttcc
     4621 gattgccttt attctaccaa aaaaaggcga gcaactcaac agaagaacgt ttatttagtg
     4681 tacttaaatt aaatattctt aaacactgaa gagagaacac atactatggc tgagattaaa
     4741 gctaaactgt gttctctttt tgtttgagaa aggacgttac aatcgatgtt gagcgaaatt
     4801 tattcagcta ttcttaaaaa cggcttacgt acatacaaat atcgaaacag caccatgaaa
     4861 cctgcaggtc atattgattc cagtaggagt ggtgctatct ttgcgtaccg tagcaagcaa
     4921 ttaatgaatg ttgggcgtgg tatggtcatt acttcggaag aagctatttt agagaacgaa
     4981 aagaaactaa cgcattggac acctaatacc tatcgctttg gtacttatgc ggatgattat
     5041 cgaacagtgg ttaaaggtca ttctgagaaa aacttaagtc aaatcaacac atttgtagtt
     5101 gatatcgatt caaaagagaa ccatcaaggc gaaattattt tagcctgttt agatcaagtg
     5161 ggctacatgc caacgctaat tttagaatca gatcatggtt atcaagttta ttttgtacta
     5221 aagacaccag gctatgtcac aaagaaaagc aatttcaagg tgatcgatgt agcaaaaaaa
     5281 atttcaaaaa caattcgtct acagttggct gaaaaattgt ccggagtgga tctaggatgt
     5341 aaccacttcg gaattgctcg attcccacaa gaaaataata ttgtttttaa agaaatgaac
     5401 tatcagtatt cttttgctga ctggattcaa tggtcgatga agcttgaatc agatcaaaaa
     5461 acaaaagaag atcgagaacg aaaactaatt gtctttcctg agaaaaaaga aattcgtcaa
     5521 gtagatgaac cgtggttcga tatgttactt cataaagcaa acatcgtcgg cggagaagga
     5581 cgtcttggtc gaaataatgt gattttcacg ctttctttag cttattactc ttcaggttat
     5641 gcattggata cttgcgaata caatatgttc acattcaacg aacggttaca ggaaccgcta
     5701 tctgaagcag aattagtaaa gattgtacgt agtgcttatt ctggtaatta tcaagcagca
     5761 agcagagaat tcattattga attgtgccag caatgggttt caccaacctt aaaaaataat
     5821 gatctgttca ttcaacgacg tggctggtgg aaatttaaaa agccacgaga tcaaagaaaa
     5881 tatagtcata aaaatgaatg gaaagaagat ctattggctt atctaagcga aaaaagtctt
     5941 gctagtgagc cttatttgaa cctgtcaaaa aaagaattgg cttcacaact aacgatgccc
     6001 aagcgaacac ttgataagat cttaaatgag ttacgagagg agaataaagt cttctacaag
     6061 gtaacacgag gaagaaatgg cggaatgatc attgcttcag tcaaaacgtt gttcgcgagg
     6121 gttattcaac taagtaaaga aaagagacta gattattcaa caaggatcac agaggtattt
     6181 ggactcaacg agagcttagt agaagagaca tttagacaat tatcaacccc cttgaaccct
     6241 cttaaagaag tgaatctttt tgaagtagat acaggttgaa aaataaaagg tgcaaattgc
     6301 cctatacaat atatctatga tacttctgta ggtgttgctc cctttgccta gctacgtgta
     6361 ggtggtatac ttataactgc gtatgcagtc ttatgtatca tggaggaagt tgtatgtcgt
     6421 taaaaaatta tgtctattca catcctgtta atgtgtttat cattggtcgt ttgggattat
     6481 ctgtggaagt gttctgtgag ctttatggtt ttaagcaggg gactttgtct tcttgggtta
     6541 ccagggaaaa aacagttgct tctttgccga ttgagtttct tcatgggttg tccttagctt
     6601 ctggggagac tatggatcag gtatatgatt gtttgtgtgt gttagagcag gagtatattg
     6661 agtataaaat agctaacgag ttaagaaaaa ggaagaagta tatccagtag tagtttttat
     6721 ttacttaaaa aattggttca ttgagcaacc tatcgctgct aaagtagcaa aggaaaacgt
     6781 taaaggaaag aatttaggga agaaatcgaa atgaaatcgg acgactggat tgaacacacc
     6841 tggcttcctc tgaaaagaaa tagcaaacga aagaaatttt gggtattgca attatggcca
     6901 ttaggaaaac tttgtagtta cggggcacga cttattcttg atttaaccgt ttactcgatt
     6961 ggagtatttg gaacggctta ttacttgata aatgatccca ataggattgc agcatcagac
     7021 atttttacag tgctaatgac gttgattttt gtcatgctat tgtctatttt tactcaatta
     7081 gtcatgcaat ttaccaggca aaaattaaca gcaggaaaac ttttcaaaag cctattcgat
     7141 ttaattgttg taaatgcaat tctagcgact ttaataaaac aaattgaaca atctggaaga
     7201 acaacaaaag gagtgaagga ttttttattg acgtttattc actttgtaaa tggacacatg
     7261 tatttgtttg aagtgggtat tattctcttt tttgtcgggt atgtatccac gaaacttatt
     7321 aaacgttcaa ttgaaaaaga aattgaaatt gacctgattc cgacacttct tggttatgag
     7381 tacaatgttg attttggaag atatgacgaa ttgatcaata cggatatcgt tcacacgagt
     7441 atccatgaat ctactgttaa gggcatcaga tctattttaa aaaatggcca ggaaatgaaa
     7501 gcaatagatc gaagaaaaga gatctacaat ttttatgaag tcgaagcaag cctacgatat
     7561 ggcatcggaa aattgtggtt agatggaagt aatattcgtc aaaacaaacc atacattttt
     7621 tggaacagta gtgatttaga acttccaatg aaagataaat aattatggag aatcgtttga
     7681 aaatgattcc tctatacagg attgtgctta tagttggcat ggagttaaaa accttaaaga
     7741 aggagcagtt attcaaagtg aaagaacgtc ataatcagtt actatgtagt aaaacgggta
     7801 cgatgaacat tgaataccga acagaatatt tagaattaac gaatcaaact gattttttgt
     7861 tgattcgaaa gcaacaagag caagaaaaaa attaatggct acttatagcc aattgattga
     7921 tgaatgggaa caattcaagg aatctaaaat tccagaacgt ctctaaaagc ctttatttgt
     7981 aaagagcata aggaaacgtg ggaacacttt ttaaaaaaag tgttccaata ggctgtgcct
     8041 attacgtttc tcaaaaataa atgtgggaac aaaatattta aaaataggat agtgaaagga
     8101 tagtgaagga tagtaaaagg agggtagtag gatagcaaaa aggataggct ccttttcgct
     8161 atccttttta aattggagga attaatatgg aagtaagaat aagaaatgtg gatgagaaaa
     8221 tcgtaagaga aattgatcga agatgtgacg aa
//
LOCUS       DAZULR010000082         8056 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.087, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000082 DAZULR010000000
VERSION     DAZULR010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8056
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.087"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..523
                     /locus_tag="ACG8ZV_002553"
     CDS             <1..523
                     /locus_tag="ACG8ZV_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997817.1"
                     /translation="EKAIPYIAAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTIS
                     NEINQYREREPEIQPAEVKQEHKNTVETAEQKNIVPVGSLWIDKKDGKVMEEDTGRTL
                     HLKDAAFIEDPQHNQVILKGKSYGKEIQTALPSEEFALGNSFRFSLETVSEVAKRKNE
                     IYYEQQLSQKERV"
     gene            584..2053
                     /locus_tag="ACG8ZV_002554"
     CDS             584..2053
                     /locus_tag="ACG8ZV_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HFS4997818.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKHERQNF
                     LVGDDRLDHAVAFLWKDPQTGETVGASYQGTIVDFNRFGKRGTYKHIDKNPTPNHGFN
                     LKIGDPKHLKFFESSIDLLSYAALNREKLQDAWLVSMDGLKHHVISHYVEESISELRR
                     KQTFPQSIEICVDNDRAGHIFYEKEQMKGIVDPFTNKKIRCERGIPNDWQVPKEYKAT
                     YEAVAKEMSVEPEAIMAIHKTETNLQLTNQLVSAHDVQSTFGKMLAKGEPVETIDLKE
                     ACTTVAKELKVCERADGTYNFDRFYSRKANIKDVNAGILLSYKAEQYYKGYKKHEHEF
                     VPEVKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            2064..4173
                     /gene="topB"
                     /locus_tag="ACG8ZV_002555"
                     /pseudo
     CDS             2064..4173
                     /gene="topB"
                     /locus_tag="ACG8ZV_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
     gene            4189..4338
                     /locus_tag="ACG8ZV_002556"
     CDS             4189..4338
                     /locus_tag="ACG8ZV_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997819.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKMRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            4419..5015
                     /locus_tag="ACG8ZV_002557"
     CDS             4419..5015
                     /locus_tag="ACG8ZV_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HFS4997820.1"
                     /translation="MTKAMVYKLLEEFNGTLALKDAKKAGISPVTIKRMVDRGELDRE
                     YPGFFTLPGQFPDELFMAQKKYERGIISHITALDLYDLTDMIPRQIDLTVPYGYHVSE
                     KGLKEFAVELHYTKAEWYELGKIEIKSRYGNPIIAYDPERTLCDIWNPWYTVEDEIKV
                     KAIKNYMESDRKNLRKLNEYRRILPTDKTMRSYIMALN"
     gene            5028..5927
                     /locus_tag="ACG8ZV_002558"
     CDS             5028..5927
                     /locus_tag="ACG8ZV_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HFS4997821.1"
                     /translation="MTPTQLKAKVKNISREKEVDPQLVLRHFMMEKFLEKISESPYRE
                     NFVLKGGFLIGSKYGIENRTTKDIDTTLREMKVTKETLTTVLNEIFSTPTKEGIQFEI
                     QGMKETREADYYPGFSLRVLAHLENMRPDFKVDVTTGDSIYPATITHSHKLMFEDRTI
                     PLESYPTEQIIAEKLSATFDFLTDNSRGKDFYDLYTIPKMEKIDEKTLKDSVRNTFTR
                     RGKTDPLKIYYEKDMDVLKNSHELKDTWKKYQKSNPYAASITYDETMDSISNLMEKVI
                     HVEEKERKLAYQRHQQMNREMER"
     gene            5930..6415
                     /gene="ssb"
                     /locus_tag="ACG8ZV_002559"
                     /pseudo
     CDS             5930..6415
                     /gene="ssb"
                     /locus_tag="ACG8ZV_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            6437..6694
                     /locus_tag="ACG8ZV_002560"
     CDS             6437..6694
                     /locus_tag="ACG8ZV_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997822.1"
                     /translation="MAKKISLTMDLLIPVIAFIDGISLGVTENPLVNRIAKGSLFLVF
                     VYLVCSYLLKRAGKDNSFWRLTKVTVAATAVILTAILPLYM"
     gene            complement(6853..6975)
                     /locus_tag="ACG8ZV_002561"
     CDS             complement(6853..6975)
                     /locus_tag="ACG8ZV_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HFS4997823.1"
                     /translation="MKGVSLLSAYETIQTILGFGMFTIALISLIVNMLKNDKKK"
     gene            7130..7389
                     /locus_tag="ACG8ZV_002562"
                     /pseudo
     CDS             7130..7389
                     /locus_tag="ACG8ZV_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328871.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            7837..8043
                     /locus_tag="ACG8ZV_002563"
     CDS             7837..8043
                     /locus_tag="ACG8ZV_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HFS4997824.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPYTVECDCGERAKCIKSYCLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
BASE COUNT         2922 a         1395 c         1701 g         2038 t
ORIGIN      
        1 ggagaaagct attccttata ttgcagcatg gacgaagaat ggtcagacgt tggatgataa
       61 ggaagctgcg gaacgtggga aaatcatgaa tgatgtcagc cgtgtcgcaa atgaattcat
      121 tcaaaccatt tctaatgaaa tcaatcaata cagagaaaga gaaccagaga tccaaccagc
      181 agaagtgaag caggagcata aaaatactgt agaaacggca gaacaaaaga atattgttcc
      241 tgttggttca ctttggatcg acaagaaaga cgggaaagta atggaagaag atacgggtcg
      301 aacgttacat ttgaaggatg cggcgtttat tgaagatcca cagcataatc aagtaatttt
      361 aaaaggaaaa agttatggaa aagagatcca aacggcgtta ccttcagaag aatttgcgct
      421 aggaaattca ttccgatttt cacttgagac agtgtcagaa gtggcaaaac gaaaaaatga
      481 aatctattat gaacaacaat tgtcacaaaa agaacgtgta taaaacaagt aaaaaagact
      541 atctgaaaaa cggatagtct tttttctttt gggaggtttt aaaatgaccg agaaaaaaat
      601 gagtcttatt gatcgatgta aacagatcga tatagtggat tttgctcgaa acaatggaat
      661 ggctgtagtc aataaaggac gagactatcg cttagaagac catgattcat ttgtttttga
      721 tcgaagaaaa caacgttttt attggaacag tcaaaatatt agtggcgaca ttattgaatt
      781 agctaaactt tttttcatag acaaagagat ccaagaccct aagcaacaat ttaaagcagc
      841 cactgatttt attctaaaga atgaagacaa aacagaacga gtggaaaatc ttcattttga
      901 gacagaaaag tacaaagatc accccgttga ttatcaacca ctcacagaaa aaggaaggaa
      961 ttatctgaag gaagaacgaa aactaccaga gtggctgatt gattatgcag aaaaagaagg
     1021 gttgattgct gaactaaagc cgaaacatga acggcaaaat tttttagttg gagacgaccg
     1081 tttagatcat gcggttgctt ttttatggaa agatccacag acaggagaga cagtaggggc
     1141 aagttatcaa ggaacgatcg tcgattttaa tcgtttcggt aaacggggaa cgtataaaca
     1201 cattgacaag aatcctacgc caaatcacgg atttaattta aaaataggcg atccgaagca
     1261 tttaaaattc tttgaaagta gtattgatct gttaagttac gctgcattga atcgggagaa
     1321 actacaagat gcctggttag tttcgatgga cgggttaaaa catcatgtaa tcagtcatta
     1381 cgttgaagag tcgatttctg aattaagacg aaaacaaaca tttcctcaat cgattgaaat
     1441 atgtgtggac aatgatcgtg caggacatat tttttatgaa aaagaacaga tgaagggaat
     1501 cgttgatcct tttaccaata agaaaatccg ttgtgagcga ggaattccaa atgattggca
     1561 agtacctaaa gaatacaaag ctacttatga agcagtcgca aaagaaatga gtgttgaacc
     1621 tgaagcaatt atggccatac acaaaactga aactaattta cagctgacaa atcaattggt
     1681 gtctgctcat gatgttcaat ctacgtttgg aaagatgttg gcgaagggcg aaccagtaga
     1741 aacaattgat ttgaaagaag catgtaccac ggtcgcgaag gaactgaaag tatgtgaacg
     1801 cgcagatgga acatacaact ttgatcgttt ttatagtaga aaagccaaca taaaagacgt
     1861 taatgcagga atccttcttt cctataaagc agaacaatac tacaaaggct ataaaaagca
     1921 tgaacatgaa tttgtacctg aagtgaaaaa ggattggaat gatcaattga agcatgagat
     1981 ccagcaacaa gaaatcagaa agcaaaaacg tgcgatgttg tttcaacaag gcagacaaca
     2041 agaaagggag tgaagtcgtc actatgaaaa ccgtcatttt agcagaaaaa ccgtcacaag
     2101 cgaaggctta tgccgatagc ttttctaaag ctacccgaaa agatgggtat tttgagatcc
     2161 aagatcgatt gtttacagga gaaactgtga tcacgtatgg ttttggtcat ttagtcgagt
     2221 tatattcgcc cgatatgtac gatgaaaaat ggaaacaatg ggcattagaa catttgccta
     2281 ttttccccaa tcaataccac tatcatgttc ctaaagataa gaaaaagcag tttagtgtcg
     2341 tcaaacgaca gctgcagtca gctgatacga ttgtgatcgc gactgatagc gatcgtgaag
     2401 gggagctgat tgcctggtca atcattcaac aagcaggcgc caatcaagga aaaaccttta
     2461 aaagactttg gatcaactcc ttagaaaaag aagccattta tcagggattc caacagttac
     2521 gagacgcaga agagacctat ccaaaatttg aagaagtaca agcacgtcag atcgccgatt
     2581 ggttaattgg gatgaacggt agcccactgt atagtttact cttgcagcaa aaaggcatac
     2641 caggaagttt ttctttaggt agagtccaaa ccccaacact ctatatgatt tatcaattgc
     2701 aggaaaagat tagaaacttc caaaaagaac catattttga aggaaaagcc caagtaatcg
     2761 ctcaaaatgg cgcatttgat gcgaagcttg atccaaatga aacccaagcg acacaagaag
     2821 catttgaagc ctatttaaaa gaaaaaggtg ttcaattagg aaaacagcca ggtacgatcc
     2881 ttcaagtcga aacagagaaa aaaagtgcgg ctagcccacg tcttttttct ttatcgagcc
     2941 ttcagtctaa aatgaatcaa ctcatgaaag ctagtgccaa agatactttg gaagccatgc
     3001 aagggttgta tgaaggaaaa tatctaagct atccgcgaac ggatacccct tatattacgg
     3061 aaggggaata tgcgtatctg ttggatcact tagacgaata caagcatttt ttaaaagccg
     3121 aagcgattcc gactcctatt catacaccga atagtcggta tgtgaataat aagaaagtcc
     3181 aggaacatta cgcgatcatt cctacaaaaa cggttatgac agcagcggct tttgaacaac
     3241 taagtccact gcagcaggct atttatgaac aagtgttaaa aacaacggtg gccatgtttg
     3301 cggaaaagta tacctatgaa gaaacaacga tcttgacgca agttcagcag cttcagttaa
     3361 aggcaatcga aaaggtgccg ctagatctag gttggaagaa gttatttgga aaagagagcg
     3421 acggaaaaga gaaggaagaa gagccgctac ttcctaaagt gacaaaagga gaaatggtga
     3481 cggtggatct acaagttctt gaaaaagaaa ccaagccacc acaaccttat accgaaggta
     3541 cgttgatcac tgcaatgaaa acagctggga aaaccgtgga tagtgaagaa gcgcaatcca
     3601 tattgaaaga agtggaagga atcggtacag aagcgacacg ggcgaatatt attgaaacct
     3661 tgaaacaaaa ggaatatatc aaggtagaga aaaataagct cgtggtgacg aataaaggga
     3721 ttttgctttg ccaagccgtg gaaaaagagc cgctgcttac gagcgccgaa atgaccgcca
     3781 aatgggaaag ctacttgtta aagatcggtg aacgaaaagg aacacaaacc acttttctag
     3841 ccaatatcca aaaatttgtc tctcacttat tggaagtcgt accagggcaa atccaatcca
     3901 ctgattttgg atcgacgtta caagaagtga aagcagccag tgaaaagcaa gaagccgcgc
     3961 gtcatttagg aatttgtcca aaatgccagg aacaagaagt cttactctat caaaaggtgg
     4021 cagcttgtac gtctgaagcc tgtgatttta aaaggtcaga agggttcatt tgaagcaacg
     4081 attgttttaa aagaagactt cactacaggc tttgaatttt ctgaaaagaa aaaaacgaac
     4141 ttcaagaaaa gaacacgccg cactgcaaaa taatggaggg ttaatcttat gcgtaatacc
     4201 acacacaaac aacaagaaat cgaaaatcaa aaagccaaaa ttcgttcaga acaggaaaaa
     4261 atgcgtgcca gcaaacgaag actgcagcaa ttgaagaacc agcagaggat tcaaaaagaa
     4321 atcgaattag atcgataaaa tcttcctaac tattgtatac gtataaactt atgttatact
     4381 gtttttataa gtttatacgt atacaaagga gggagaaaat gacaaaagca atggtataca
     4441 agctgctaga agaatttaat ggaactttgg ctttgaagga tgccaaaaaa gcgggcattt
     4501 ctcctgtaac gatcaaacgt atggtagatc gaggggagct ggatcgagag tatccaggtt
     4561 ttttcacctt acctggtcaa tttcctgatg aattgtttat ggcgcaaaaa aaatatgaac
     4621 gcggcattat ttcacatatt accgcgttag atttgtatga tttaacagat atgatcccta
     4681 gacagatcga tctgactgta ccttacggtt atcacgtttc tgaaaaagga ttgaaggaat
     4741 tcgcagttga gctacactat acaaaagcgg aatggtatga attaggtaag attgaaataa
     4801 aaagtcgcta tgggaatcct attatagctt atgatccaga aagaacttta tgtgacattt
     4861 ggaatccctg gtataccgtt gaggatgaaa tcaaagtaaa agcaatcaaa aactatatgg
     4921 agtcggacag aaaaaatctt agaaaattga atgagtatcg acgaatttta ccaacagaca
     4981 aaacgatgcg ttcttatatt atggctttaa attaaaggag aagatacatg acacctacgc
     5041 agttaaaagc aaaagtgaag aatatttcta gagaaaaaga agttgatccg cagcttgttt
     5101 taagacattt tatgatggaa aaattcttgg aaaaaatctc agagtctcct tatcgtgaaa
     5161 attttgtgtt aaaaggcggc ttcttgattg gctcaaagta tggcattgaa aatcgcacaa
     5221 ccaaagatat tgatacgact ttacgggaaa tgaaagtaac caaagaaaca ttaacaacgg
     5281 ttctaaacga aattttttca acgccgacga aagaaggcat tcaatttgag attcaaggaa
     5341 tgaaagaaac gagagaagcc gattactatc caggatttag cttacgtgtg ctggcacatt
     5401 tggaaaacat gcggccagat tttaaggtag atgtgactac aggtgactcg atctatcctg
     5461 caacgatcac tcacagtcat aaattgatgt ttgaggatcg aacgattcct ttggaatcct
     5521 atcctacaga acaaattatt gctgaaaaat taagtgcaac ctttgatttt ttaacagata
     5581 attcgagagg aaaagatttt tatgatctct atactattcc taaaatggag aagatcgatg
     5641 agaagacctt gaaagatagt gtgagaaata catttacacg tcgaggaaaa actgatccgt
     5701 taaagatata ctatgaaaag gatatggatg tactgaaaaa tagtcacgag ctaaaagata
     5761 cctggaagaa atatcaaaaa agcaatcctt atgctgcgtc gatcacgtac gatgagacaa
     5821 tggattcgat tagtaatttg atggaaaaag tgattcacgt cgaagaaaaa gagcgaaaac
     5881 tagcttatca aagacaccaa cagatgaata gagaaatgga gagataaaga tgattaataa
     5941 tgtgacatta gtaggacgct taaccaaaga tcctgattta cgttataccg caagtggtac
     6001 tgcagtagcg acttttaccc tagccgtcaa ccgaaatttc acgaatcaaa acggcaattg
     6061 agaagccgat tttattaact gcgtgatttg gcgcaaacca gcagaaacaa tggcgacatt
     6121 agctaaaaaa ggtagcttga ttggtgtagt tgggcggatt caaacgcgga cttacgacaa
     6181 ccagcaagga caacgtgtat atgtgactga agttgtagca gataactttc aactattaga
     6241 aagtaaagca gcgacagaga gccgtgcgca cgctgatcaa tcgtccacca gtccaagcac
     6301 cgccaccttt gaacaacgga atacagcgac gcctaacaac aatggattga acgcttcaca
     6361 gaatccattt ggtggacaat caatcgatat tagcgatgat gatctaccgt tttagtttga
     6421 gaaagaagga gtaagcatgg caaaaaaaat tagtctgacg atggatctat tgatacccgt
     6481 aattgcattt atagacggga tttctttggg cgtcactgaa aatcctttgg taaatagaat
     6541 tgcgaaagga tcactatttc ttgtattcgt gtatcttgtc tgttcttatc ttttaaaaag
     6601 agcaggaaag gataattcct tttggcgatt gactaaagtc acagtagcag cgacagctgt
     6661 tatacttacg gctattctac cgctttatat gtagagttaa cgggaaatcg ttgaacttct
     6721 tgcgaaatat tgctataatg aacatgaaaa agaggagttg cgctaacaac ccctcattaa
     6781 cagcaccgat taaagaacgg tggcagaata ttagttattt ggaaataacc gctgacctgc
     6841 taaagtagac ggttatttct ttttgtcatt tttaagcata tttacaatca aactaatcaa
     6901 agcaatggta aacataccaa aaccaagaat ggtttgaatt gtctcatatg cggacaaaag
     6961 gcttactcct ttcatagatt ttagcactta cattcataag caccaccacc tttccagaag
     7021 tcgccaccgt cttcaaactt tactgtcttg actattatag catatctaaa atcgaataaa
     7081 aattctcaat tttagctgtt tttgctataa ttttagcgag gtgatcgtga tggaacaata
     7141 tattggttta ctcgataaat tagggtgatc aagacacagc cattgcttgt gcgatttaca
     7201 ttacgcacga gtcatgaacc aatcaattgt gtagtggcca atatagaaat agcggataaa
     7261 ttgctgattt tggaagaagg caagtatact atttcagtga caggtcactt caataaacga
     7321 aatcaactag tcattgaatc aatgcaaatt agaaaccctg atcattttac gagattaatg
     7381 ggcatataaa taaaagaaga gctgcagtcc taaatgagga ttgcagctct ttttgtttta
     7441 catagaaaca agaaaaatga aaaggccttt ttaggaaggc gcaagcgcct tctcaattga
     7501 aaaacctctc tctcactcca accgccaccg ccgttcgaga agaaaggaag tgaacgttgc
     7561 acgttcacta agataagggg tcttgcaaag caagacaaaa tagaaaaaac ttcctctcac
     7621 caaaaggttc gttcctgttc gctatctctt tattgatttg ccagaccggc aacaagttgc
     7681 cttttatcac caaaaagcga caaggacaag ggtaaatggc acgctgcacg cccttgtcct
     7741 tgtcgctttt agttgattca ttctggccaa caaatcaata aagaaagaac taacgaaagg
     7801 aagtaaaacc tttcctaaga ggaggcagaa tcaatcatgc gaaagaaatt tgattattgg
     7861 ggtgttccct tcagcgaatt attcccaaac tatcatgcac catatactgt cgaatgcgat
     7921 tgtggagaaa gagcgaaatg tatcaaaagc tattgtttgt atcaatgtcc aacatgcggg
     7981 aaaaaatata ccttgtctta tggcgattat attttgattg atgagaaagg aaagaaacgc
     8041 tgatgaaaac acaaca
//
LOCUS       DAZULR010000083         7907 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.088, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000083 DAZULR010000000
VERSION     DAZULR010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7907)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7907)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7907
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.088"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..199)
                     /locus_tag="ACG8ZV_002564"
     CDS             complement(<1..199)
                     /locus_tag="ACG8ZV_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997825.1"
                     /translation="MKKMGKCILCEKYTQLTKEHVPPKKSGNTGGKKTRTGNLDDFLK
                     SDFTKGDFPKGIKRKPQGNVYY"
     gene            complement(362..1996)
                     /locus_tag="ACG8ZV_002565"
     CDS             complement(362..1996)
                     /locus_tag="ACG8ZV_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFS4997826.1"
                     /translation="MEMIQTKRVALYIRVSTQEQALEGHSIQAQEQNGRQFAERMGYE
                     VVEVYADEGISGKSTKNRFAYQRMMNDARNHRFDLLVIWKLTRLGRNMLDVLQTVEEL
                     LRYDVGLHSISEQFDVTTSTGKLMLQLLGSFGEFERNQIAENVQMSMQSLVKDKKRYA
                     GGRRLGYVSGIDTNGQKQLVIEPEEAKIVRLIYAKYLGGAGYRAIANFLNRQGYQTVK
                     KNAFSTTAVKDILRNKIYAGYLEYARYINWETKRRKGKNPRPILVKGTHEPIISEEDY
                     QKVQERLALEGKQPKWNHTGENVLTGLLRCPECGAPMAASNVTNTLKDGTKKRIRYYS
                     CSVFRNKGASVCHANSIRAEQAETFVADRLKEIVQLPEVLPRLVAALNEEIVRQSQPL
                     EQELVVLLERKEELKTKIEKWEAALEDSPELFPMLKDRLDELTEKRRQLHIRENEILG
                     IFQQGEPIQVKDVQRILTSLDRFLAQSEKKQIKALYRTFIEKITFDPNHKEMLEITMK
                     FTHAVVQQLNEQYQIAVSKTKDTAIFVLKTPFTLTI"
     gene            complement(2000..3373)
                     /locus_tag="ACG8ZV_002566"
     CDS             complement(2000..3373)
                     /locus_tag="ACG8ZV_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFS4997827.1"
                     /translation="MRVACYDRTSVYEEAKISNDAQYDAVKEYVLEKYEQIPQRFSDK
                     GESGEKAERPAFRQLRAWVCASEEEGVIYVWRYDRLARQAKIALEFIELCQQHQVQVY
                     SISEPLPASFSHASTNKLFVQLLFTFAEQQRNVIIENVRAGLSYKKQQRQYLSSAVPY
                     GYRLVNGKIQQEVHEARIVRYIFQLYLTKKYGYKKLCQRLTQQKLFFRERPFQPYHIY
                     SILKNPLYYGEIKGGSLGKYLGTFEPILSKATFLQAQEIRQSRCTAKKDTYLYLLRQK
                     IRCPFCGRHLSSKYQWNTKKTKTLHYYHCTDRSCQGIFLRAERVESEVLEKIQAFFQY
                     EGVYQALIAQLTQQLAEKRKDEKRKVIQQKKQEAQWIKAFEEGNCSLEELKQQLQALQ
                     KPMSTSSFLSLQQCEAKVKEWLQLKDLSSRQLLCDYVCRIEVTKDKTVCGIYFRQLTQ
                     NILERNE"
     gene            complement(3389..3628)
                     /locus_tag="ACG8ZV_002567"
     CDS             complement(3389..3628)
                     /locus_tag="ACG8ZV_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997828.1"
                     /translation="MTKNKMTLKAEVLLYIQEHFSNQAFFTKPIYLDFEIRGVSAGSI
                     GGTLQALKNEGYLENHFVQRSFNRRVVKKWYLVHS"
     gene            complement(3810..6485)
                     /locus_tag="ACG8ZV_002568"
     CDS             complement(3810..6485)
                     /locus_tag="ACG8ZV_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF927 domain-containing protein"
                     /protein_id="HFS4997829.1"
                     /translation="MKMNHTSIQKHLQLLNTLGISYVNLRTFSTLNKKTVSHIFSTAD
                     SQAIINYLEKQKLSEGTVNITYNPIKQEVITQKKHSVRDNDIEKIRFVFIDIDPKRKE
                     GSATDSEKKKAENVMEQVERYLKEKRIESFVKVDSGNGYHIFLPINEQPNNHETILTI
                     QNFLQLLHRRFGVEDEVDIDTSVYNPSRLCKLVGTPAVKGKSTKERPHRLSSFLSIPD
                     NIDRSNCFKILEQIVEENSMMSTSRVKSHPSFREVLPFIQADYKQWLAHYPELTYTIK
                     EGDHKGVTLLIFDECPLRKHTNNSNGSCLSVTADNKIRFHCLHASDKNKDIQDFVKKY
                     PLPKPVNPSVESLESNQEYYFDQFKLNQEGVFLVKEGQEEKVACPMFIKQIRKNIEQK
                     VITLVLAYYVDHCWDEIEIEGGCLQTNNFKQLAKHGLIIKARREAEVVDFLQIQRENA
                     PIFFEHESLGWKKENEAMIFQLQDSFGREIPSVLTKNSCYQLTTNGTEAEFDALVHKY
                     VLGTNLELAWSIGIASIVLGYLNVTKANTFLSLLINLQGKSTTGKTTTLHFIASLFGN
                     PTTVLRNMNATNKAIIKLASNNQGGVPLILDELGAATQNNFSSLIYQLASGEERLRLD
                     SNCQLMPQETFSVLTLTSSEERLENYFNEKLTGLKVRYIEFSDIKFTKDANHAEKVKS
                     LSSNTFGWGIKLFLLKLFEQGITKIEATFVEAQKKLWAVLPEHSLKQRIGNNLALIYS
                     GALLIQDILGYPLRLEHIQTVLINSYEQLIVDTSLGSEQTVFDRVKTLLVMNSHKFLT
                     NSDNKHTPSTIWGKVSIQKNGDIKVNIFPIPFEDLLRREFQVKDLTYLFRQLLDSGNM
                     CAEKGRRTKRIHMNRQVLPTYEILLPSSLKSYFRL"
     gene            complement(6668..7591)
                     /locus_tag="ACG8ZV_002569"
     CDS             complement(6668..7591)
                     /locus_tag="ACG8ZV_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997830.1"
                     /translation="MATNYAKKINFDVDKLYKSLIVVPKNKSEDGNYELEVLQFKIEQ
                     KSSERFMSNQLVKIKKWLPMIDQLVSNNKEAKNLCIFVLLLHGRVINLVNRKSTTKFA
                     NSFWFLKNINKTVEKNGVYKGDFHFQNAETIEREHHYFDLLVNTVVELAKWAKSNETY
                     SQVLKRIMSQETSFIYELSKSNLKYTYNEDELEILDNPENSQWIKELKREDFIETLRI
                     LKSLFDLKLAKATIMGIERDSYYWEEIGLYAPQIEGEDKEKRIDNIINYINSLSEPLK
                     CRGLDFIGTLGWTETYYEKIYKEIIEQYFPK"
BASE COUNT         2306 a         1555 c         1207 g         2839 t
ORIGIN      
        1 tataataaac atttccttga ggtttccttt taatcccctt cggaaaatca ccttttgtaa
       61 aatcgctctt aaggaaatca tctaaattac cagttctggt ctttttacct ccagtattcc
      121 ctgatttttt aggtggtaca tgttctttag taagttgagt gtatttttca cataaaatac
      181 acttacccat ctttttcata tctatcccca ctctttttaa ttcttatata caattatatt
      241 tcaaatattc attaataaat atccctattt atgataagga cctccctaac tacttctcta
      301 acgatttcaa atcgctagag aagcgttagc gcccctctaa cgttgtttga tataacctag
      361 actagatcgt taacgtaaag ggtgttttta acacaaaaat agccgtatcc tttgttttgg
      421 atacggctat ttgatattgc tcattcaatt gttgtaccac ggcatgcgtg aatttcatcg
      481 taatttccaa catctcctta tggttaggat caaaggttat tttctctata aaggtacgat
      541 acaaggcttt gatttgcttc ttctcactct gggcaagaaa acgatccaaa ctagtcaata
      601 tccgttggac atctttgact tgaatcggct ctccttgttg aaagatccct aagatttcat
      661 tttctcgaat gtgcaactgt cgtcgttttt cagtcaattc gtctaagcgg tcttttaaca
      721 tcggaaacaa ttcaggacta tcttccaaag cagcttccca tttttcaatt ttagtcttca
      781 attcttcctt tcgttccagt aacaccacga gttcttgttc caatggttgg ctttgtcgca
      841 ctatttcttc atttaacgct gccaccaatc ggggaagaac ttctggtagc tgaacgatct
      901 cctttaatcg gtcggcgaca aatgtttccg cttgttcggc acgaatcgaa ttggcatgac
      961 acacacttgc tcctttattc cgaaagactg aacaagaata atatcgaatc cgtttctttg
     1021 tgccatcctt tagggtattt gtgacattac tcgctgccat cggtgcgcca cattctggac
     1081 aacgtaacaa gcctgtcaat acattttcac ctgtatggtt ccatttgggt tgttttcctt
     1141 ctaaagcaag gcgttcttgt actttttgat aatcttcttc cgaaataatc ggttcatggg
     1201 ttcctttcac taaaatcggt ctcggattct tccccttccg tcgtttggtt tcccaattga
     1261 tgtagcgcgc atattctaaa taccctgcat aaattttatt gcgtaagata tctttgactg
     1321 ccgtggtaga aaaagcattc tttttgactg tttgatatcc ttgacgattc aaaaaattgg
     1381 caatcgctcg ataccctgct ccgcctaaat attttgcata gatcagacga acaattttcg
     1441 cctcttctgg ttcaatgacc aattgttttt gaccattcgt gtcaatacca ctgacatagc
     1501 ctaaacgtcg gcctcctgca taacgctttt tatctttcac taagctttgc attgacattt
     1561 gaacattctc cgcaatttgg ttgcgttcaa attcaccgaa actcccaagg agttgtaaca
     1621 tcaatttacc tgtcgaagtg gtcacgtcaa attgttccga gatcgaatgt aatcctacgt
     1681 catatcgcaa taattcctcg actgtttgta agacatctaa catattgcgt ccgagacggg
     1741 tcaatttcca aatcactagt agatcaaaac gatggttccg agcatcgttc atcattcgtt
     1801 gataggcgaa ccgatttttt gtggatttcc cactgattcc ttcatcggca taaacttcta
     1861 ccacttcata gcccatccgt tcggcaaact gtcgtccatt ttgttcttgt gcttgaatac
     1921 tatgtccttc taaagcttgt tcttgtgtac tcacgcgaat atacaatgcg actcgtttgg
     1981 tttgtatcat ttccatagat cattcgttcc tttctaaaat attttgtgtc agttgtcgga
     2041 agtaaatccc acaaactgtt ttatcctttg ttacctcaat ccgacaaaca tagtcacata
     2101 ataattgtcg actagagagg tcttttagtt gaagccattc tttcactttt gcttcacact
     2161 gttggagtga aagaaacgaa gaagtagaca tcggcttttg aagagcttgc agttgttgct
     2221 tgagttcttc cagtgaacaa ttgccctctt caaatgcctt aatccattgt gcttcttgtt
     2281 tcttttgttg gattactttg cgtttttcat cttttcgctt ttcggctaat tgttgcgtta
     2341 attgggcaat caaggcttga tagacgcctt cgtattgaaa aaaagcctgt atcttttcca
     2401 atacttctga ctcaaccctt tctgcccgaa gaaaaattcc ttggcagctt cggtcggtac
     2461 aatgataata atgaagcgtc ttcgtcttct ttgtattcca ttgatacttc gaactcagat
     2521 gacgaccaca gaagggacac cgaatttttt gacgtaataa gtacagatac gtatcttttt
     2581 tagctgtaca ccttgattgg cgaatctctt gggcttgtaa aaaggttgct ttcgagagaa
     2641 tcggttcaaa ggttcctaga tacttcccca aagatcctcc tttgatttcg ccatagtaca
     2701 atggattttt taggatacta taaatatgat agggctgaaa aggacgttcg cggaagaaaa
     2761 gcttttgttg cgtcaatcgt tgacaaagct ttttgtagcc atattttttg gtcaaataaa
     2821 gttgaaaaat atagcgaaca atccttgctt cgtgtacttc ttgttggatt ttcccattca
     2881 ctaaacgata cccatatggt accgcagaag acaaatattg ccgttgttgc tttttatagg
     2941 aaagtccggc acgaacattc tcaataatga cgtttcgttg ttgttctgca aaagtgaaca
     3001 ataattgcac aaatagttta ttcgttgacg cgtgtgagaa agaagcagga agaggttcag
     3061 aaatcgaata cacttgaacc tgatgttgtt ggcacaactc aataaattct aaggctattt
     3121 tggcttgacg tgccaatcga tcataacgcc aaacatagat caccccctct tcttctgacg
     3181 cacaaaccca agctctaagc tgtcgaaaag ctggacgctc cgctttttcc cctgattctc
     3241 ctttgtctga aaatcgttgg ggaatttgtt catatttctc taaaacatac tctttcactg
     3301 catcatattg agcgtcatta ctaattttcg cttcttcata aacagacgtt cgatcataac
     3361 aagccacacg catgcttgat tcccctctct atgaatgaac taaataccat tttttcacga
     3421 ctcttctatt gaacgaacgt tgcacaaagt gattttctaa atatccttcg ttcttcaacg
     3481 cttgaagagt acccccgata gatccagcag atacccctct tatttcgaaa tccaagtaaa
     3541 ttggttttgt aaaaaaggct tgatttgaaa aatgttcttg aatatacaga agaacctctg
     3601 cttttagtgt cattttattt ttagtcatta gaattttcct ttctttcatg tttgattgaa
     3661 tgaagtaaat gaagcataga tcaagcttca tttacttccg tttgggtttg ctcgctatca
     3721 tacagataag taatcagttg ttttgctaaa tcaataagaa atatttccat aacatggtgc
     3781 ctcactttca tactttggtt tattctaaat tacaatcgaa aatacgattt gagtgaagaa
     3841 ggtaatagaa tctcgtatgt tggaagaact tgacgattca tgtgaatacg tttcgttctt
     3901 ctcccttttt ctgcacacat attacccgaa tcaagcaatt gcctaaaaag ataggttaga
     3961 tcctttactt gaaattctcg ccttaacaag tcctcaaacg ggataggaaa aatatttacc
     4021 ttaatatccc catttttttg aattgatact tttccccaaa tcgtactggg cgtatgtttg
     4081 ttgtcactgt ttgttaaaaa tttatggcta ttcatcacca acaatgtttt cactcggtca
     4141 aataccgttt gctcacttcc taaactagta tctacaatta actgttcgta cgaattaata
     4201 agcaccgtct gtatatgctc taatcgtaaa ggatagccca gtatatcttg aattaggagg
     4261 gctccactat aaatcaaagc tagattatta ccaatgcgtt gcttcaaaga atgttcaggt
     4321 aaaacagccc atagtttttt ttgagcttcg acaaaagttg cttcaatttt tgtaatccct
     4381 tgttcaaaga gtttcaaaag aaataacttt ataccccaac caaaagtatt agaagaaaga
     4441 cttttaactt tctctgcgtg attcgcatcc tttgtaaact tgatatcaga aaattcgata
     4501 tatcgaactt tcaaaccagt taatttctca ttgaaataat tttccaaacg ctcttcagaa
     4561 gaggtaaggg tcaaaacaga aaaagtctct tgtggcataa gctgacaatt agaatctaat
     4621 cttagccttt cttctcctga agctaattga tagatcaacg agctaaagtt attttgagtt
     4681 gctgctccta actcatctag tattagtgga acacctccct gattgtttga tgctagcttt
     4741 ataatggctt tattggtagc attcatattt ctaagaaccg tagttggatt tccaaataaa
     4801 gaggcaataa agtgtaacgt agtggtttta cccgttgtgc tcttgccctg taggttaatt
     4861 agtaaactca aaaaagtatt agccttcgta acgtttaaat agcctaacac aatagaagca
     4921 ataccaatcg accaagcaag ttctaagttc gttcctaaaa catacttatg aaccaatgcg
     4981 tcaaattccg cttctgtacc attagttgtt aattggtagc atgagttttt agttaataca
     5041 gaaggaattt cacgtccaaa agaatcttgt aactgaaaaa tcattgcttc attttctttt
     5101 ttccagccaa gagattcatg ttcaaaaaag attggagcat tctcccgttg aatctgtaaa
     5161 aagtcaacga cttcagcttc tcttctagct ttaatgatta agccatgttt tgctaattgt
     5221 ttaaaattat tagtttgtaa acatccacct tctatttcta tttcatccca acaatgatcg
     5281 acataatagg caagaacaag tgtaatgact ttttgttcga tatttttgcg tatttgctta
     5341 ataaacatcg gacaagcaac tttttcttct tgaccttctt tcaccaaaaa tactccttct
     5401 tgattcagtt taaactggtc aaaataatat tcttgattgg attctaatga ttctacagaa
     5461 ggatttacag gttttggcaa cggatatttt tttacaaagt cttgaatatc tttattttta
     5521 tccgaagcat gcagacaatg aaatcgaatc ttattatcag ccgtaacaga caaacaagaa
     5581 ccattagaat tattcgtgtg ttttcttaat ggacattcgt caaatataag taaggtaact
     5641 cctttatgat cgccctcttt tatggtataa gttaattcag gatagtgagc taaccattgt
     5701 ttatagtctg cttgaataaa aggtaacact tctctaaaag atggatggct ttttactcta
     5761 gaggttgaca tcatggaatt ttcttcaact atctgttcaa gaattttaaa acaattactt
     5821 ctatctatgt tatcgggaat agaaaggaaa ctagataaac gatgcggacg ctcttttgtg
     5881 gactttcctt tgaccgctgg tgtaccaact aatttgcata atcttgaagg attataaaca
     5941 gaagtatcaa tatcaacttc atcttctact ccaaatcttc ggtgaagtaa ttgaagaaaa
     6001 ttctgaatag taagaatcgt ctcgtgatta tttggttgtt catttatggg aagaaaaata
     6061 tggtagccat tcccactatc aacttttaca aatgattcta ttctcttttc tttcaaataa
     6121 cgttctactt gttccataac attttctgcc tttttctttt cgctatctgt tgcacttccc
     6181 tctttccttt tagggtcaat atcaataaat acaaaccgaa ttttttcaat atcattgtct
     6241 ctcacagaat gctttttttg tgtaatcacc tcttgtttaa taggattata agttatgttt
     6301 actgtacctt cagacaattt ctgtttttct aaatagttaa taattgcttg agaatctgca
     6361 gtagaaaaaa tatgagaaac ggttttcttg tttaatgtag aaaaagttct caaattaaca
     6421 taagaaatcc ccagtgtatt taacagttgt aaatgcttct gaattgaagt gtgattcatt
     6481 ttcattaatt accactcact ttctaaaaaa tttttatttg tatgactaca ttacctccaa
     6541 cctctcataa tttcatgatc ttcagttcta caaaaatata tcccactcaa aatcttgaca
     6601 aaagaaaaaa gttgtgattt tggaaatcac aacttttttc ttttacgata aatcaatcct
     6661 tattaaatta tttaggaaaa tattgttcaa ttatttcttt atatattttc tcatagtatg
     6721 tttctgtcca tcctaatgtt cctataaaat caagtcctct acattttaaa ggttcactta
     6781 aactattaat atagttaata atgttgtcta tccttttctc tttatcttca ccttcaatct
     6841 ggggagcata tagtccaatt tcctcccaat aatatgaatc tctttcaatt cccatgatgg
     6901 tagctttggc taatttcaaa tcaaataacg attttagaat tcttagtgtc tcaataaagt
     6961 cttctctctt caactcttta atccattgtg aattttctgg attatctaaa atttcaagtt
     7021 catcttcatt ataagtatat ttcaaatttg acttgcttaa ctcatagata aatgaagttt
     7081 cttgactcat aattctttta agtacttgac tataagtttc gtttgacttt gcccatttcg
     7141 ctaattctac cactgtattc actaataaat cgaaataatg atgttctcgt tcaatagtct
     7201 cagcattttg aaaatgaaaa tcacctttat aaactccatt cttttccact gttttattaa
     7261 tattttttaa aaaccagaat gagtttgcaa atttagtcgt actttttcga ttaactaagt
     7321 taataactct tccatgtaat aataagacaa aaatacataa atttttagct tccttattat
     7381 tagatactaa ttgatcaatc atagggagcc attttttgat tttcactaat tgattgctca
     7441 taaatctttc actggacttt tgttcaatct taaattgcaa aacttctaac tcataattcc
     7501 catcttctga tttatttttg ggaacaacta tcaaactttt ataaagttta tccacatcaa
     7561 aatttatctt ttttgcataa tttgtagcca ttaatacatc tccttattca taataaattt
     7621 catatgacgc tcctctcaaa atttaccggt agactagaaa aaagaataaa agatacgtca
     7681 attcacactt tattcttaaa aaaaaactgg tctctctacc ggtaatatcg attgagtccg
     7741 cctttatcga ctttatcctt tttttatatc tgatttgtca aattaagcta gacaatatgt
     7801 ctttatctat gcagctcaaa aatacttcca atggtgttcg ataatttaat gattttcttg
     7861 gaatatggtt tcttttcgag gcaacggatt gaataaaggt ttcatcc
//
LOCUS       DAZULR010000084         7894 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.089, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000084 DAZULR010000000
VERSION     DAZULR010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7894
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.089"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            204..683
                     /locus_tag="ACG8ZV_002570"
     CDS             204..683
                     /locus_tag="ACG8ZV_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6530 family protein"
                     /protein_id="HFS4997831.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNMDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            716..2944
                     /locus_tag="ACG8ZV_002571"
     CDS             716..2944
                     /locus_tag="ACG8ZV_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFS4997832.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKERTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            3073..4716
                     /locus_tag="ACG8ZV_002572"
     CDS             3073..4716
                     /locus_tag="ACG8ZV_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HFS4997833.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKHALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(4789..5334)
                     /locus_tag="ACG8ZV_002573"
     CDS             complement(4789..5334)
                     /locus_tag="ACG8ZV_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HFS4997834.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(5357..5842)
                     /locus_tag="ACG8ZV_002574"
     CDS             complement(5357..5842)
                     /locus_tag="ACG8ZV_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFS4997835.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(5832..6644)
                     /locus_tag="ACG8ZV_002575"
     CDS             complement(5832..6644)
                     /locus_tag="ACG8ZV_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HFS4997836.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(6783..>7894)
                     /locus_tag="ACG8ZV_002576"
     CDS             complement(6783..>7894)
                     /locus_tag="ACG8ZV_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HFS4997837.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT         2675 a         1506 c         1559 g         2154 t
ORIGIN      
        1 aatattccaa catcatcttg gactttctac atgttactaa tgagcgtgta aaagaacgag
       61 atggtgtttt tatttctatc aatgaagctc tttttctttg caatcctcac ttcaatcctc
      121 tataatgtcg catatagttt agtaaatgag taaactacta atttacttat ttactaaaaa
      181 taaaaggatg aggagttaaa ataatggaaa taccaacaaa tttaaaacat aaaccagtaa
      241 tcgttgtaga agactatgat aaagttgatg gaagaaatgc attaaatatg gatgcaaaag
      301 ggctttcact gggccttgct cagtggaatg atcgtggaaa agtcgatatc tcaggcaagg
      361 tatggcgaca tactggagaa aaatggtcac gacagtcgga agaattacca atcacacgta
      421 ttttagattt agcgatctta gctgcgcaag gaagtttata cttccaagat gcttatcgtt
      481 atgaaaaatt ttatgatcca gaaaatccag tcgtagacat cattggatta caagggaacc
      541 gaatgacggt agaagtagat accaaaaatc caaagatcga tgaagacatc attttgtatt
      601 acgatacact acaaaaagac ggagaactga ttggggaacg attccgtatt ttaaaacgtc
      661 ttttagatga gctaggatat taatagacag agatgatcaa aaggggaaga gaagcatgga
      721 gaatttctca ctaacagaaa accgaacctt ttcacggcta gaaaagcaaa tgatctggaa
      781 gaaaccgaaa agccatcgga caagtgcaga agaatggcgg atcgcctccg aaatcaaagg
      841 gaattggcaa gatcctgaaa tgaaaatcag taacgtactt ttggaaggag atgccgggtc
      901 ggggaagaca caattagcca aagcactatc tgctgatctg caacttccct atacaaaagt
      961 gacctgtttt gcagatatgg acaaatcaga tgttttcgga gccttattac ctgtagtaga
     1021 ttctaataag gaacaagacc aagaattact agaagctatt taccaaacag atacacttga
     1081 agctgtactg acactgatcc agaaccatta cggcattgat cctttttctg ctaaagaaaa
     1141 attagcagag ctagttcaaa ggatcgaagc tgattatcca gatgcaatcc attacagcta
     1201 ttacccttct gaaatcgttc gagcgattga aaaaggctat ttattagaga ttcaagagcc
     1261 gactgtcatc cgagatgcct ctgttcttgt ggcacttaac tcagcgctcg aaccaaatgg
     1321 gatgttgaat ttaccgacag gaatcattcg tcgccatcca gattgcgtca ttgtgatcac
     1381 tacaaatcga aattaccaag gaaatcgccc attaaatgaa tctttaagag atcggatgca
     1441 acatgcggaa aaaatggatc ttcctgcctt agaagtcatg gcagaacgtg cgatggcgaa
     1501 aactatgatc caaaaacaag aacttctctt aaagatggca gagattatcc gtttgttgga
     1561 tgaaactgca aaagctaacg ccatcaaagg tgtagcagga atgcgttctt atttttattg
     1621 ggcaaatacc tataagcaag gacaagattt actccagtcg atttatccaa aagttttgta
     1681 taaattatcc actgattcag atgaattggc aattcttgaa caagctttgt ctgacagtgg
     1741 attgctactg gaacttcagg acatattgag aaaagaaaaa tggggtcatc ctcaatctga
     1801 gcatacaaaa gaaagaacca ttagcgccga agaagcaaat gaacgaaaca tcactgaaaa
     1861 tgctgaagaa attctgcgct tagatgaaaa gaaatcgttg tctgctgaag aaccaaatga
     1921 gggagaagag aaacaagaag aaacaataga aaaaaacgag attcctcctc aaatgcaaaa
     1981 agaacgcagt agcgatatcg aaggaaaaaa tcaaaaagaa caacaaacag gagatgattc
     2041 tcaagaaatg tctgcttctg acatggaagc acatgataag gaaatcaaga agcaactgaa
     2101 taaagaagcg cgacaaatca tgaaggaaac gattcatgaa aaagaaggtc tcatcgttca
     2161 ccgaccagct ttccaaggaa aaacgccgga agcacgtgag ctacacatgc aagtaatgcc
     2221 aatagtagaa tcacttagcc ggcaaatttt agagttactg gataatgaac aaacagagac
     2281 gtaccaaaaa ggaaaatacg aaggtcagcg gttcaatgca agcaaagtag catatggtga
     2341 tttgagaaat tttgacaaaa agaacccgcc acatgagcaa ccttctttag cggtagctgt
     2401 acggatcgat gaatctgggt caatgatacg ggatgatcgg atcgaagcgg caaaaaaagc
     2461 agcgattgcc attgccgaat tttctaagaa agtcgatatc ccattgttga tttacggaga
     2521 tacagcagac cgttcgtcaa gagaaaagac ttctttgttt tcttataaag aatttgaaga
     2581 cggatttcaa tggttaaatg aaaaattagt cactatgaaa ccaaggcaaa acaatcgtga
     2641 tggtgctgca cttcgtttag cagcagaaaa attaaacaga caatccgcaa caaccaaact
     2701 gttgcttaat attagtgacg gtcagccaaa agcattgccg gattatacag gcaaaaaagc
     2761 aaaagaagat atccagtctg ttttgaaaga atatgaacgt caaggaatcc tatttgtctc
     2821 cgcagctatt ggccaagaca aagaagaaat caagtcgatc tacggtgaaa gtcgttttgt
     2881 agatattact gacttgaatg aatttcccaa gcaaatgatt caactgattg cccgctatct
     2941 atgataaaat aaagctcaac gaacgcactt agcagattcg ttgagctttt cgtttctagt
     3001 taccggtaac aaggatactt ctaaaataga atcggttata atcaagaggg accgttaaag
     3061 gagtgaaacg atatgataca agaacaaaaa tggtggaaag aagcagtagg ctatcaaatc
     3121 tatcctgcta gtttcaaaga tagcaatggc gatggtcaag gagacatcaa tgggatccgt
     3181 gaaaaactta attatttgaa agatcttggt atcggcttta tctggatcaa tccgatctat
     3241 caatctccat ttgtcgataa tggttatgac gtaagtgact atcaagatat agaagagaga
     3301 ttcggaacga tggaagattt tgatttattg ctaaaagaag cacatgaatt agggatcaaa
     3361 gtgattatgg atcttgtcat caaccatagt tcggatcagc atcaatggtt tgaagaatcg
     3421 aaaaaatcta aagaaagccc gtatcgcgat tattacattt gggtcgacgg ggtagatggc
     3481 aaagaaccga ataattggac atcgattttc ggcggttctg cttgggagta ttctcatgaa
     3541 actggacagt attatctgca tgtttttgca aaagaacaac cagacttaaa ttgggaaagc
     3601 gagaaattga aagaagaact attcaatatg atccgatggt ggttggataa agggatagat
     3661 ggatttcgtt tagatgcgat ttctcatgta aaaaaagatg aatattcagt aaaagccaca
     3721 gagaaccctt tctcaccctt tcaaaatgtc tcaggaatcg aagaacattt gaccgatttg
     3781 aaacatgttt ttgaagagta cgatatcatg actgtcggag aagcaagtgg tgtcactgca
     3841 gaagaaggac cacaatgggt agggaaagac ggttatttcg atatgatatt cgaatttgat
     3901 catatccata tctggcagca agaaaaagaa gggcaattag atgtccttaa attgaaacat
     3961 gcattaagcg cttggcaaac ttcattggat ggtatcggat ggaacgcttt atatatggaa
     4021 aaccatgatg ttcctcgtgc cgtttcagtg tttggagata ctcgtcccga tttttgggct
     4081 atgtctgcaa aagcaatcgc tatgatgtat ttctttttgc aaggtacgcc atttatttat
     4141 caaggacagg aaatcggaat gacgaatatg ccctttgaat cgatcgatca agttgatgca
     4201 gtagattcga aaagacttta taaaaggctg cttgcggaag gtaagacaag agaagaagca
     4261 ttggatatca ttcgtgaaac aacgagagac aacagcagga cacccatgca atggacttcg
     4321 gaacaatatg ctggtttttc tacacatgaa ccttggctga tcactaatcc aaataccaaa
     4381 acgatcaatg tagaacaaca agaatatgaa ccagagtcgg tcctgcaatt ctataagaac
     4441 atgatccgca ttagacaaac caataaaggt ctgatatacg gttcttataa agaatatctt
     4501 catgaacatc cacaacttta tgtctatgaa agatatttag aagatgaaca atatcttatt
     4561 atggtaaact taacagaatc acttgctgac tatgaacttc caaaagaagc agatcagtcc
     4621 tggacattac tcttgtcaaa ttcctctagc ggagaatttg aagctaaagg catactagca
     4681 ccttatgaag ctcggttata taaaacaaac aagtaaaact tcctcgttaa agttcattag
     4741 ttggactttg cgaggaagtt tttcagattg ctctgtcaat tactcatttc aataattcgc
     4801 tctaggacca ccgatatatt taggacgaga gcgaagggct gtcacgtgag cttgtccaag
     4861 ggttttcaaa cgaggtctga caggtacttg gacatgcttg atatgcatac cgattgatgt
     4921 gtcaccgata tcgataccgg cttgtccaac tacgtgttcc acttcgacag gatcattgaa
     4981 ctggtcaaaa gcagcaacag aacaagcacc tccagcatgt agtgcaggaa caacagagac
     5041 aatttcgaaa ttttttgctt ctgccactgt tcgttctact actaatgctc ggttcaaatg
     5101 ttcacaacct tggacagcta gcgcaatttc tttaggatcc aacaactctt ttaacgtacg
     5161 gatgatccat tgaccaactt ccgcactgga attttttcca atatgtcctc caacgacttc
     5221 gcttgtgctg catcctaaaa caaaaagatc accttttttc aagtgtgcct cagccaatat
     5281 gtcattaact atttcagtca attggtcttt taattctttt tctgacaact tcattttcta
     5341 aaaccttctt tttcaattaa tattgcttcc gtgcttgaat acgttgaaga cttgcagtta
     5401 taggaaaggc aagtcccatt ccaatcagat tttggaagat gtttcctggt atagaagcca
     5461 ctccagccgg ccaatcatat aaaatccaac cggcgatacc atagccgatg atcataacta
     5521 agcttcctaa taaaagccct aatccccaca tacgagtaga agatttgctg aaagaaccag
     5581 caacatatcc ttgtaacccg tggatcacta atgaaaaaac tgcccactgc ggatatcctg
     5641 aaatcaaatc gatcaataga ccactggaag caccaacaac taatccaccc gttggaccat
     5701 aaagaaaagc agcggtatag atcccggcct cgcataatgt cacaaatcca ttcgtagccg
     5761 gtacagggat caaaattgtt aatgaaaggg caactgtcaa cgcaatcagc atagcataga
     5821 tcgttaattg cttagttttc atttctcatt cctccttttt gaataccgcc agaccagaca
     5881 cttccggtat gatcgttcat cagcacgcca ttagaaatac aatgggcaac aaatttttta
     5941 ctttctgcta ctgctttggt aaaatctgcc cctaacacaa gattcgctgt tattgcagaa
     6001 gaaaaggcac aaccggcccc gtttactgtt gtagtgtcga tttttttatg agaaaatacc
     6061 tcataatgat caattgaata gagaagatcc acagcttcat ctccagccat ccttgtgccg
     6121 cctttgatca caatgttttt tgttcctgaa gcagtgagtt ctttagcgag atggatcatt
     6181 tctgttaacg aagagggaag agcttgacca gaaagtaaag cagcttctgc caaattaggc
     6241 gtaatcatcg taacaagtgg aaaaagttct tcgatgagct gcgaaatata caattgattg
     6301 atcacagctt cagtttcttt gaatgccaaa acagggtcta aaatgattgg gatattttgt
     6361 tttgttttta tgaagtctcg aacaaccatg attgcttcac ttgaattcaa taacccaatt
     6421 ttgataccat ctaatgaagt cattttatca atcgaaacta actgtcgttt aagcaattcc
     6481 aaagatatag attccagcat aaatcgctca ttaatatcta gtgcccctat agaagtcaag
     6541 gcgcttagtc cgaatagacc aaaattctca aaagttttta aatctgtttg gattcctcca
     6601 ccagcaaatg gatcagaacc gccaattgtc aagattcttt tcataacatt ttcctccatg
     6661 aataagagta taacgaaatt ttcaaaaaag aaaaacagcc aattggcata tttttatctc
     6721 atccaattta aaaaaacaaa aagaaaagaa agaccaaaat ggatctttct ttccttaaat
     6781 agttaggact tttgtgattt taattctttc tcgatttgaa gccgttgcac tttcattgta
     6841 gctgttcgcg ggattgcatc aaaatcacgg atgataggga cgttcaagcg aggaagttca
     6901 tggacttgct cccaccatcg attccaatcc atttctttat caggagctaa agcaataatc
     6961 ggttgtggag aatgattttt atcccttaca atcactactt ctgccaaaaa atctaacgaa
     7021 tctaataaaa agtcttcaat agctaatgta ctattgatcg tttcgatcaa atccacttgc
     7081 cgatctttca aaaataggtg gccatgctta tccataaaac cgtaatctcc gctatcccac
     7141 caatcgccat aaacattttc ctggaaccgt gcatcttcct tgtaataagt caaagcccgt
     7201 cctttagaca gtaattgtat atgaccatct gtgttttcag gtaggacatt cccaactgaa
     7261 tctgtaatcc gagcgcttgt catgtcttcc agtccaacgc ccatatctct tgcatcactt
     7321 gttttcaaac tctctagtgt atgagcctta agaatcattg gtccgcattc actttggcca
     7381 tatacttgaa gaaataccgc atcctgtgcc atcgacgttc gcaaaaatgt cttcattgtc
     7441 tggttgttta tagcatcaaa agtggagtga tagtatcgga tacccgaaaa agcttctgga
     7501 tgctccttag cagtaaaacg ccactgaaca aagttattcg gatgggtctc tagtgcaatt
     7561 ggccggtgag cttccaacat atgaacaact tttgaacttt gtgcgtttgc taaaggcatc
     7621 ataggaaatc ccatggacat caaagaagag ataccaatat tgaatctgga atgcactgga
     7681 gagatgtgaa aagcgattaa tttcttttcc gaaatttttg tgaaaactgt tttttgccat
     7741 ttcgtccgcc atcccataga atgagcagaa tgacaaataa gtttagggat accagttgta
     7801 ccagaagtat gggtcatata agaaatttca tttttgtcta aaaatgattg agaaacagac
     7861 aaagcaggtt gttccattaa ataaagaata ggaa
//
LOCUS       DAZULR010000085         7794 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.090, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000085 DAZULR010000000
VERSION     DAZULR010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7794
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.090"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..523
                     /locus_tag="ACG8ZV_002577"
     CDS             <1..523
                     /locus_tag="ACG8ZV_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997838.1"
                     /translation="EKAIPYIAAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTIS
                     NEINQYREREPEIQPAEVKQEHKNTLETPENKNIVPVGSLWIDKKDGKVMEEDTGRTL
                     HLKDAAFIEDPQHNQVILKGKSYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNE
                     IYYEQQLSQKERV"
     gene            584..2044
                     /locus_tag="ACG8ZV_002578"
     CDS             584..2044
                     /locus_tag="ACG8ZV_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HFS4997839.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKYERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQIKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNAFFGQQLSVNDSIEAINLKD
                     ICREVAKELKVCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            2055..4259
                     /gene="topB"
                     /locus_tag="ACG8ZV_002579"
     CDS             2055..4259
                     /gene="topB"
                     /locus_tag="ACG8ZV_002579"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFS4997840.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQVGADQGKTFKRLWINSLEKEAIYQGFQQLRDAKETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FKKEPYFEGKSEVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGMIRQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLRAEEISTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTEATYES
                     LTPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPIDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGVLLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSIDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            4275..4424
                     /locus_tag="ACG8ZV_002580"
     CDS             4275..4424
                     /locus_tag="ACG8ZV_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997841.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKLRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            4499..5092
                     /locus_tag="ACG8ZV_002581"
     CDS             4499..5092
                     /locus_tag="ACG8ZV_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HFS4997842.1"
                     /translation="MQEKLKELLAIRDGNLSMKEARKLGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEIEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            5105..6004
                     /locus_tag="ACG8ZV_002582"
     CDS             5105..6004
                     /locus_tag="ACG8ZV_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HFS4997843.1"
                     /translation="MTPTQFAAKTRNLAKRTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTAQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIIGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            6007..6504
                     /gene="ssb"
                     /locus_tag="ACG8ZV_002583"
     CDS             6007..6504
                     /gene="ssb"
                     /locus_tag="ACG8ZV_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFS4997844.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMVTLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSTSPSTTTFEQRDTATPNNNGLNALQNPFGNPFGGQSIDISD
                     DDLPF"
     gene            6870..7130
                     /locus_tag="ACG8ZV_002584"
     CDS             6870..7130
                     /locus_tag="ACG8ZV_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997845.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            7575..7781
                     /locus_tag="ACG8ZV_002585"
     CDS             7575..7781
                     /locus_tag="ACG8ZV_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HFS4997846.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGQRAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
BASE COUNT         2871 a         1329 c         1628 g         1966 t
ORIGIN      
        1 ggagaaagct attccttata ttgcagcatg gacgaagaat ggtcagacgt tggatgataa
       61 ggaagctgcg gaacgtggga aaatcatgaa tgatgtcagc cgtgtcgcaa atgaattcat
      121 tcaaaccatt tctaatgaaa tcaatcaata cagagaaaga gaaccagaga tccaaccagc
      181 agaagtgaag caggagcata aaaatacttt agaaacgcca gagaataaga atattgtgcc
      241 cgttggttca ctttggatcg acaagaaaga cgggaaagta atggaagaag atacgggtcg
      301 aacgttacat ttgaaggatg cggcgtttat tgaagatccg cagcataatc aagtaatttt
      361 aaaaggaaaa agttatggaa aagagatcca aacggcgtta ccttcagaag aatttgcgct
      421 aggaaatcca ttccgatttt cacttgagac agtgtcagaa gtggcaaaac gaaaaaatga
      481 aatctattat gaacaacaat tgtcacaaaa agaacgtgta taaaacaagt aaaaaagact
      541 atctgaaaaa cggatagtct tttttctttt gggaggtttt aaaatgaccg agaaaaaaat
      601 gagtcttatt gatcgatgta aacagatcga tatagtggat tttgctcgaa acaatggaat
      661 ggctgtagtc aataaaggac gagattatcg cttagaagac catgattcat ttgtttttga
      721 tcgaagaaaa caacgttttt attggaacag tcaaaatatt agtggcgaca ttattgaatt
      781 agctaaactt tttttcatag acaaagagat ccaagaccct aagcaacaat ttaaagcagc
      841 cactgatttt attctaaaga atgaagacaa aacagaacga gtggaaaatc ttcattttga
      901 aacagaaaag tacaaagatc accccgttga ttatcaacca ctcacagaaa aaggaaggaa
      961 ttatctgaag gaagaacgaa aactaccaga gtggctgatt gattatgcag aaaaagaagg
     1021 gttgattgcc gaactaaagc caaaatatga acggcaaaat ttcttagttc gagacgatcg
     1081 tttagatcat gcggtcgcct ttttatggaa agatccacag acaaaagaga cagtaggggc
     1141 gagttatcaa ggaacgttca ttgattatga acgttttggt gagagaggca catataagca
     1201 tatagataaa aattcgacag cgaatcatgg ctttaaccta aagatcggtg accctaagca
     1261 gataaaattt tttgagagta gtattgattt acttagctat gctgcactga atcgtgatca
     1321 gttaaacgat acgtggttag tctctatgga agggttaaaa caccatgtga tcagtcatta
     1381 ttttggtgag gcagtatctg aattgagaaa gaaacaagcc tttcctcaat ccatcgagat
     1441 ttgtgtggat aatgaccgtg caggacatat tttctacgaa aaagaacaat taatgggcgc
     1501 agtcgatcca tttacgaatc agaaagtacg ttgtgaacga ggaatcgcta atgattggca
     1561 agtgccaaaa gaatacaaaa tcatttatga agaagtcgca aaagaagaaa aggtcacacc
     1621 agaagctatt atggccatac acaagacaga aaacaatctg caattaacga accaactggt
     1681 ttccgctcac aaagtaaatg cgttttttgg ccagcagctt tctgttaacg attcaataga
     1741 agccattaat ttgaaagata tttgtagaga agtcgcaaaa gaattaaaag tttgtgaacg
     1801 cgtggatggt acgtacgatt ttgatcgttt ttatcaagaa aaaggggata ttaatgcgca
     1861 gattcttttc tcttataaag cagaacaata ctacaaaggc tataaaaatc atgaacatga
     1921 atttgtacct gaagtaaaaa aggactggaa cgatcaattg aagcatgaga tccagcaaca
     1981 agaaatcaga aagcaaaaac gtgccatgtt gtttcaacaa ggcagacaac aagaaaggga
     2041 gtgaaatcgt catgatgaaa accgttattt tagcagaaaa gccgtcacaa gcgaaagctt
     2101 atgccgatag cttctctaaa gccactcgaa aagacgggta ttttgaaatc caagatcgat
     2161 tgtttcctgg tgaaactgtg atcacgtatg gttttggtca tttagtcgaa ttagattcgc
     2221 ccgatatgta cgatgaaaat tggaaacaat ggtcattaga acatttgcct attttcccta
     2281 cacattatca ctatcatgtt cctaaagata agaaaaagca attcaaggtg gtgaaacagc
     2341 aacttcaatc ggccgacacc attattattg cgacagatag cgatcgtgaa ggggaactga
     2401 tcgcttggac gatcattcaa caagtaggcg ccgatcaagg aaaaaccttt aaaagacttt
     2461 ggatcaactc cttagaaaaa gaagccattt atcagggatt ccagcagtta cgagacgcaa
     2521 aagagaccta tccaaaattt gaagaagcac aagcacgtca gatcgccgat tggttaattg
     2581 ggatgaacgg tagcccactg tatagtttac tcttgcagca aaaaggcata ccaggaagct
     2641 tttccttagg cagagtccaa accccaacgc tttacatgat ttatcaattg caggaaaaga
     2701 ttagaaattt caagaaagaa ccttattttg aaggaaaatc cgaagtaatc gctcaaaatg
     2761 gcgcatttga tgcgaagctt gatccgaatg aaacccaagc gacgcaagaa gcatttgaag
     2821 attatttaaa agaaaagggg gttcaattgg gaaaacagcc aggcatgatt cgccaagttg
     2881 aaaccgagaa aaaaagcgcg gcaagtccac gtcttttttc tctatccagc cttcagtcta
     2941 aaatgaatca gctcatgaaa gctagtgcca aagacacttt ggaagccatg caaggcttgt
     3001 atgaagggaa atatctaagc tatccgcgaa cggatacccc ttacattacg gaaggggaat
     3061 atgcgtatct gttggatcac ttagacgaat acaagcattt tttgagggct gaagaaattt
     3121 cgactcctat tcatacaccg aatagtaggt acgtgaacaa caagaaagtc caggaacatt
     3181 acgcaatcat tcctacaaaa acagttatga cagaagcgac gtatgaaagt ctgacacctt
     3241 tacaacaagc gatttacgag caagttttaa aaacgacagt ggcgatgttt gcggaaaaat
     3301 atacctatga agaaacaacg atcttgacgc aagtccagca gcttcagtta aaggcaatcg
     3361 gaaaagtacc gatagatcta ggttggaaga agttatttgg caaagagagc gacggaaaag
     3421 agaaggaaga agagccgcta cttcctaaag tgacaaaagg agaaatggtg acggtagatc
     3481 tacaagtcct tgaaaaagaa accaagccac cacaacctta taccgaaggt acgttgatca
     3541 ctgcgatgaa aacagctggg aaaaccgtgg atagtgaaga agcgcaatcc atattgaaag
     3601 aagtggaagg aatcggtaca gaagcgacac gggcgaatat tattgaaacc ttgaaacaaa
     3661 aggaatatat caaggtagag aaaaataagc ttgtggtgac gaataaaggg gttttgcttt
     3721 gccaagctgt ggaaaaagag ccgctgctta cgagtgccga aatgaccgcc aaatgggaaa
     3781 gctacttgtt aaagattgga gaacgaaaag gaacacaaac cacttttcta gccaatatcc
     3841 aaaagtttgt ctctcactta ttggaagtcg tcccaggaca aatccaatcc attgattttg
     3901 gatcgacgtt acaagaagtg aaagcagcca gtgaaaagca agaagccgcg cgtcatttag
     3961 gaatttgtcc aaaatgccag gaacaagaag tcttactcta tcaaaaggtg gcagcttgta
     4021 cgtctgaagc ctgtgatttt aaattatgga caacgattgc caaaaagaaa ctcacagcga
     4081 cacagctgaa ggagattatt caaaatagcc gaacaagcca accagtgaaa gggttaaaag
     4141 gtcagaaggg ttcgtttgaa gcaacgattg ttttaaaaga agacttcact acaggctttg
     4201 aattttctga aaagaaaaaa acgaacttca agaaaagaac acgacgcacg acaaaataat
     4261 ggagggttaa tcttatgcgt aatacaacac acaaacaaca agaaatcgaa aatcaaaaag
     4321 ccaaaattcg ttcagaacaa gagaaattac gtgccagtaa aagaagactt cagcaattaa
     4381 agaaccagca acggattcaa aaagaaatcg aattagatcg atagacatta accttgttac
     4441 aaatacacta tcatgatata tttaatgtag tgtatttgta acaaaagggg ggaagtaaat
     4501 gcaagagaaa ctgaaagaat tgttggctat tcgcgatgga aatttatcta tgaaggaagc
     4561 cagaaaatta ggaatcgcag caaccactgt acaaagattg gtgaatcaag gaaaattgat
     4621 caaagttgat cgtggttatt atgtagagga tggtcatgga atagatgatt tattttggct
     4681 tcagcaacgt ttttccaggg gaatcttctc tcatgaaacg actttagata tttaccagct
     4741 ttctacgaat atgccgaaat tcattcactt aacttttccc catggatata acgttgatcg
     4801 ttcaattaca aaagagcagc agttacaatt tcatttcgtg aagaaagaag tttatgaact
     4861 aggaaaagta gagggaactt cctttcaagg aaatcctatt actatgtatg ataaagagcg
     4921 tacactttgt gatatttgga atccgagata tgaaattgaa tatgaaatga aattagaagc
     4981 attaaaagag tacatggaag acccattgag agatccaagt aaattaagag attacatgac
     5041 aaaactacat gtagaaaaag aaatgaaata ccacatgcaa agcttatatt gatggaggaa
     5101 aaagatgaca ccgacacaat ttgcagcaaa aacaagaaat ttagcaaaga ggacaggatt
     5161 aaatgcacag ttagtacaac ggcattttat gatggatcgt ttaattgaac aaatttctga
     5221 atctaagtat aaaaatgatt tcattttgaa aggtggcttt ttattaggat caaaatatgg
     5281 aatcgataga aggacgacaa ttgatatcga cacgacattt agaaatagca aattaactga
     5341 agaaaaattg aagagtattt ttaatgattt aactaggaaa cccacgaaag aaggtattgt
     5401 tttctctatt caaggaatga aggaaacaag agaagccgat ttttatcctg gatttcaaat
     5461 taaattggtg gctaatttag agaaagtacg tgtgccattt aaaatggacg tgacaacagg
     5521 agattctatt tatcctgaag tagatacaca ctatcaccaa ttaatgtttg aagataaaaa
     5581 ggtggagatt ccagcttatc caacagcaca aattattgca gaaaagctaa gtgctacgtt
     5641 cagctttggc acagataatt cgagagcaaa agattactac gacttattta ccattccgaa
     5701 actagaaaat atcgatacga aagagttata caaaagtgtt cgaaatacat ttacaaaacg
     5761 tggggataca aaaccgttgt ccttttatta tgaaagagaa atggataaga tcataggaaa
     5821 tgactatttg gaaaagcagt gggaaaaata tcgctcagtt aacacgtttg cgaattccat
     5881 ttcatttaca gatacagtca acgaaattga tcacctaatg aaaagtgtga tcaaaattga
     5941 aaatcaagaa agaaaacggc agtttaaaag atcacaacaa atgaatcaag aaatggagag
     6001 ataaagatga tcaataatgt aactttagta ggacgcttaa ccaaagatcc agatttacgt
     6061 tataccgcga gtggtactgc agtagcgact tttaccctag ctgtcaaccg aaatttcacg
     6121 aatcaaaacg gcaatcgaga agctgatttt attaactgtg tgatttggcg caaaccagca
     6181 gaaacaatgg tgacattagc taaaaaaggt agcttgattg gtgtagttgg gcggattcaa
     6241 acgcggactt atgacaacca gcaaggacaa cgtgtgtatg tgacagaagt tgtggccgat
     6301 aatttccaac tattagaaag caaagcagcg acagaaagcc gtgcgcacgc tgatcaatcg
     6361 tccaccagtc caagcaccac cacttttgaa caacgggata cagcgacgcc taataacaat
     6421 ggattgaacg ctttacagaa tccatttggg aatccatttg gtggacaatc aatcgatatt
     6481 agcgatgatg atctaccgtt ctaagtagca ttttctattg gttgcatttg ctacggttta
     6541 tgttataatt tagtcaacaa aaagaatttt caatctataa ccaaaaacca ctagctggcg
     6601 ggctagtggt tttcttttac gtttctatta taagaattaa cgggtaggct tactgtcttt
     6661 cttggcaaat ttacaatcaa gccatttgca gatatagtgc gcggctactt ctgccatgat
     6721 tgcaaaaaca aaatcaaaaa gaattttcaa acctataacc tcctcccctt gccagattag
     6781 gccggggtag cagacagcaa gactattata gcataattga aatatccaaa tgattggatt
     6841 tttgctataa ttttagcgag gtgattgtga tgaacaaata tgttggtttg cttgataaaa
     6901 tccgagtaat aaaaacgcaa ccgttattgg ttcgctttac tttacaaacg attcatgaat
     6961 cgattaattg tgtagttgca gatattgaaa ttatcgataa attgctaatt atggatgatg
     7021 gaaaatacaa tattgccgtc acaggtcact tcaataaacg aaatcagcta gttattgcta
     7081 gcatgtatgt tagaaatccc gatcatttta cgcgatcgat gggcatataa aaaaagaaga
     7141 gttgcaatcc taatgtagga ctgcagctct ttttgtttta catagaaaca agaaaaatga
     7201 aaaggccttt ttaggaaggc gcgagcgcct tctcaattga aaaacctctc tcactccaac
     7261 cgccaccgcc gttcgagaag aaaggaagtg aacgttgcac gttcactaag ataaagggtc
     7321 ttgcaaagca agacaaaata gaaaaaactt cctctcacca aaaggttcgt tcctgttcgt
     7381 tatctcttta ttgatttgcc agaccggcaa caagttgcct tttatcacca aaaagcgaca
     7441 aggacaaggg taaatggcac gctgcgcgcc cttgtccttg tcgcttttcg ttgattcatt
     7501 ctggccaaca aatcaataaa gaaagaacta acgaaaggaa gtaaaacctt tcctaagagg
     7561 aggcagaatc aatcatgcga aagaaatttg attattgggg tgttcccttc agcgaattat
     7621 tcccaaacta tcatgcacca catactgtcg aatgcgattg tggacaaaga gcgaaatgta
     7681 tcaaaagcta tcgtttgtat caatgtccaa catgcggaaa aaaatacacc ttgtcttatg
     7741 gcgattatat tttgattgat gagaaaggaa agaaacgctg atgaaaacat aaca
//
LOCUS       DAZULR010000086         7689 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.091, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000086 DAZULR010000000
VERSION     DAZULR010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7689
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.091"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            164..895
                     /locus_tag="ACG8ZV_002586"
     CDS             164..895
                     /locus_tag="ACG8ZV_002586"
                     /inference="COORDINATES: protein motif:HMM:NF019736.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997847.1"
                     /translation="MLSEKEQENFDEYAYFVNTAIDRQSLGKVLGGKMISVVEPYYEW
                     IMDRQQLDPTTSFDMKNVNLVDDMEPYIERKLYIVNAAHAAVAYLGALKGYKTIQEAI
                     QNMEIFNLVKQFLMENIEYFVQKYHFSREELTSFVEKTLNRHGNQKLSDEITRVGSSP
                     IRKLGPNDRLIAPIVKLDSYHLPYDAGIKVIAAGYHYRNLADPEAEQLRRMIVNDGLK
                     ATIKKISRLEGKLLNEVVAAYESQI"
     gene            907..1338
                     /locus_tag="ACG8ZV_002587"
     CDS             907..1338
                     /locus_tag="ACG8ZV_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFS4997848.1"
                     /translation="MLKEQLSGNTMFMDAIDSWQEAIRVSARPLIGKGIIEESYVQAM
                     IQNVLDNGNYIILLPLVAMPHARPEFGSKGVGMSFLCLDKPVMFPSEEPVKFFFTFSS
                     DSPKGHLDLMANLGELLSDEKMYQKLFDVKTEKALLDLIKK"
     gene            1352..2797
                     /locus_tag="ACG8ZV_002588"
     CDS             1352..2797
                     /locus_tag="ACG8ZV_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HFS4997849.1"
                     /translation="MEVANKKKRVSMRAKVQAIGGFLTNMVLPNIGAFIAWGIVTALF
                     IPTGWFPNESLNELVSPTVSYLLPLLLAYTGGRMVGGTRGAVLGTIGTIGLIIGADIP
                     MFMGAMIMGPLGGWMMKKTDDFLDGKVPAGFEMVVNNFSIGIIGFILMCLSYLVVGPI
                     IQSANQFVTSAIEALVSTGFLPILSLINEPAKVLFLNNVIDQGVYYPLGMQQTLEAGR
                     SIYFMVASNPGPGLGLLLAYSLFGKKAAKQTAPGAIIIHFFGGIHEIYFPYVLMKPLT
                     ILSMIAGGMTGIITFELFDAGLVAGPSPGSIFSYLALTPRGNFLGVMAGVVTATLVSF
                     FVTSVILKADKSTDEDRNFELSVQKSKTMKSEGRKLLKEENAREICTEKKEMNKISFA
                     CDAGMGSSAMGATIFKKKLQKAGITDVEIKNYRIEEVPEDSDLVIVHQDLEERTRKAH
                     PNMKIVTLKNYLQDPVINGLAEEIIGLKTED"
     gene            3083..4708
                     /locus_tag="ACG8ZV_002589"
     CDS             3083..4708
                     /locus_tag="ACG8ZV_002589"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFS4997850.1"
                     /translation="MKKIYSKEIDCFRGIAVLAVIFYHLPNSLLPGGLQGVTIFFVVS
                     GFLMAKNTIRDEKNRQFSFLHFYYKRIKRIYPFLLFSLVVFIFILGISNIRLIGNIRS
                     ELPSLIFGYNNWWQLNQGVSYFDSYFNASLFKHYWSLSVELQFYLIWPFLFIVIKRMR
                     RKQVFYLIYTLIFVSILFSLFLPSTKAYYHTIAKLFPFLLGVWGYFNRITIGRFFEQN
                     TFSKIWLLLLASLCLILFPIFPYTLNELLISICFALLLASVDDMNIAKKTKIASTKLS
                     FVGKISYELYLVHFPVLIALTNLFKHHHWKYLDIAGLFTVFLCTLLMITCFRKGVQKM
                     RSPKIWTAMALMIIGVSVLVLRAPASRLTADQNQLQSLLKENSSKANAGENLLSQEKK
                     ILFIGDSVMLGAYQELKETFKKEALVDAKESRQITALPEILKEHKDLVSYQQIVIGLG
                     TNGVITDEAIEQTMSLLKDKKVYWVNIKAPTGWQDTINATLATLPNQYSNITMIDWYS
                     ESKNHPEFFYDDETHLNESGRTAYAKYIASVIQ"
     gene            5340..5693
                     /locus_tag="ACG8ZV_002590"
     CDS             5340..5693
                     /locus_tag="ACG8ZV_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997851.1"
                     /translation="MNSFKKKFVSRFLNMKNFFEKKGDYDAYNYVLNLEKQTYYTLRK
                     NDDNDFWTMLPKMLSIDSKLSLLEEFINLDIEEFCGGKELINMVESDYHTYYKESCGY
                     KVDEQCPQSIIFYIE"
     gene            6474..>7689
                     /locus_tag="ACG8ZV_002591"
     CDS             6474..>7689
                     /locus_tag="ACG8ZV_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4997852.1"
                     /translation="MQTFLTKTSFKKVVLLDYLLEKDNWCAMEELRNLLNVTEKSVLH
                     YIEELEDLFKQYNGNILLKNEDNKRFFIKKEKDFPIYNIYLHFYKASYNYHLIDFMYK
                     YPRSVLKDFAKEQFTSVSTVFRYAKLLIPYFRRYHITFHPFQLELNASEANIRSFFYY
                     FYWNSTRESSDKWPFHIEQKEIEKYIVAFEGIYDITLTIFQKRVFSFWLAINIERSSF
                     RKVRVDNEYKSVISDDPHFNLLKKWSKQINLSFNSDELCFLYRIIYSFGVIDGNAIYE
                     NSHAYAHQRQNTCSYRAVENLEKVLQSMFRFSLDIKDPELIFNFIAFHERSYLFYGNP
                     DLFFNRSYIEEMKEEEPRTYHIMEKLKKELQANADLDVSKKLENWAQLFLDYYYVLDY
                     YDLFLTNVKPIKI"
BASE COUNT         2706 a         1031 c         1418 g         2534 t
ORIGIN      
        1 cattcaaatc gcctttgttc gctagagtct ttagaatttc tgtagtaaaa tcgttcatat
       61 ggaagtcctc ttttctgtga atgtgttgtg gtaactctat tctacagaag ggacttcctt
      121 ttttctattt acacaaaata ttttacactc tcaaatttat tctttgctgt cagaaaaaga
      181 acaagagaat tttgatgaat atgcatattt tgtgaatacg gcaatcgatc gacaatcttt
      241 aggaaaagtt cttggaggaa aaatgatctc tgttgtcgaa ccttattatg aatggataat
      301 ggatcgacag cagttagatc caactacatc ttttgatatg aaaaatgtaa atttggttga
      361 tgatatggag ccttacattg agcgaaagct ttatatcgtt aatgctgctc atgcggcagt
      421 agcttattta ggcgcactga aaggatataa gacgattcaa gaagcaatcc aaaatatgga
      481 gattttcaat ctagtcaagc aatttttaat ggagaatata gagtactttg tacaaaaata
      541 tcatttttct agagaagaat taacatcttt tgtggaaaaa acattaaacc gtcatgggaa
      601 tcagaaactc tccgatgaaa ttactcgtgt aggaagttcc cctattcgaa aattaggccc
      661 taatgatcgt ttaattgctc ccatagtaaa actagattca tatcatttac cttacgatgc
      721 aggaataaaa gtaattgctg cgggatatca ttatcggaat cttgctgatc cagaagctga
      781 acaactacgt cgaatgattg taaatgatgg gttgaaagca acgattaaaa agatttctcg
      841 tttggaaggt aagctgctga atgaagttgt cgctgcttat gagtcccaga tttagaggag
      901 gagaatatgc taaaagaaca attgtcagga aatacaatgt ttatggatgc gatcgattca
      961 tggcaagagg caatccgagt aagtgcgcgt cctttgatag gaaagggaat aatagaggaa
     1021 agctatgtac aagcgatgat acaaaatgtg ttggataacg gaaattatat tatattactg
     1081 ccactagtag caatgcctca tgcgcgtcca gaatttggga gcaaaggggt cgggatgagc
     1141 tttttatgtt tagataagcc agtcatgttc ccaagtgaag aaccagtaaa attcttcttt
     1201 accttttctt ctgattcgcc aaagggacat ttagacttaa tggccaatct tggagaattg
     1261 ctgagtgatg aaaaaatgta tcaaaaatta ttcgatgtga agacagaaaa agcattgtta
     1321 gatttgataa agaagtaaag gagagaagaa aatggaggta gcaaacaaaa aaaaacgagt
     1381 ctccatgcga gctaaagttc aagcgattgg cggtttctta acaaatatgg tattgccaaa
     1441 tataggcgca tttattgcat ggggaattgt tactgcatta ttcattccaa ctgggtggtt
     1501 cccaaatgaa tctctgaatg aactcgtaag tccgacagtc agctatctat tgccgttact
     1561 acttgcctat actggtggtc ggatggttgg tggtacacgt ggagctgttt taggtacaat
     1621 cggaacaata ggtttgatta ttggtgctga cataccaatg ttcatgggag caatgattat
     1681 ggggccactt ggtgggtgga tgatgaaaaa aacagatgat tttttagatg ggaaagttcc
     1741 tgctggtttt gaaatggtcg tcaataattt ttctatagga attattggtt tcatactgat
     1801 gtgcctttct tatctggtag ttggaccaat aatccaatca gctaatcaat ttgtaacgag
     1861 tgcaattgaa gcattagttt caactggttt tttaccgata ctgtccttaa tcaacgaacc
     1921 ggcaaaagtc ttatttttaa ataatgttat tgaccaaggt gtttattatc cattaggtat
     1981 gcaacaaaca ttagaggcag gcagatcaat ttatttcatg gtagcatcaa atcctggccc
     2041 tggcttagga ctattgttag cttattcttt atttggtaaa aaggcagcaa aacagacagc
     2101 accaggtgca atcatcatcc attttttcgg cggaatacat gagatttatt ttccatatgt
     2161 attaatgaaa ccactcacta tattatctat gattgctggt ggaatgacag gaatcatcac
     2221 ttttgaatta tttgatgcgg gcctggtagc aggtccaagt ccaggttcta ttttttctta
     2281 tttagctcta acgcctcggg gaaatttttt gggtgtcatg gcgggagtgg tcacagcaac
     2341 actggtttcc ttttttgtaa catcagtaat tttaaaagca gataaatcaa cagatgaaga
     2401 cagaaatttt gaactatcag ttcaaaaatc gaaaacgatg aaatcagaag gaagaaaatt
     2461 attaaaagaa gaaaatgcta gagaaatatg taccgagaaa aaagagatga ataaaatttc
     2521 ctttgcttgt gatgcaggaa tgggaagcag cgcaatgggc gcaacaatat tcaagaaaaa
     2581 attgcaaaaa gcaggtatta ctgatgttga gataaaaaat tatcgaattg aagaggtacc
     2641 agaagatagt gatttggtga tcgtacatca agatttggag gaacggacta gaaaagcaca
     2701 tcctaacatg aaaattgtga cattaaagaa ttatttgcaa gatccagtaa tcaatggatt
     2761 agcagaagaa atcattggat taaaaacaga agactaattt atgggaattt ttgattaacc
     2821 tttattaaaa ttattttgcc taatataaaa aggttgtgac atggcttgtg tcgcaacctt
     2881 tttttgtcgc acaaataatt aatcggatat tttatgttca tattttttgt gatcaacgag
     2941 aactgatggg gcaaagatac attttagata cttttaactg ttaatttaca aaacaaggtg
     3001 aaacgaatag aaaaatgaaa aaatcgatac ggaagaatat gtttgattaa aacatgcatg
     3061 aagagaagga ggttgatgat acatgaaaaa aatatattca aaggaaatcg attgttttag
     3121 aggcattgct gttttagcag tgatatttta tcatttgcca aatagtttgc tgccaggcgg
     3181 attgcaagga gtaacgatct tttttgtggt ttctggtttt ttaatggcta aaaatacgat
     3241 aagagatgaa aaaaacagac aattcagttt tttacatttt tactataagc gtatcaaacg
     3301 tatttatcca tttttactgt tttctttggt cgtattcatt ttcatactag ggattagcaa
     3361 cattcgattg ataggaaaca ttcgtagtga gctacccagt ttgatttttg gctataacaa
     3421 ttggtggcag ctgaatcaag gagtatctta ttttgactct tactttaatg cttctttatt
     3481 taaacattat tggtcgcttt cagttgaact acaattctat ttgatatggc catttttgtt
     3541 tattgtcatt aagcgtatga gaagaaaaca agtgttttac ttaatctata cattgatttt
     3601 tgtttctatt ctttttagtt tgtttttacc ttcaactaag gcatattatc atacgatagc
     3661 taaacttttt ccatttttat taggagtttg ggggtatttt aatcgaataa ctattggccg
     3721 tttctttgaa caaaacactt ttagtaaaat ctggctttta ttactagcta gtctttgtct
     3781 gattctgttc ccgatttttc cttatacact aaatgaacta ctgatcagta tttgttttgc
     3841 tctattgtta gccagtgtcg atgatatgaa cattgcaaaa aagaccaaaa tcgctagtac
     3901 aaaactttct tttgtaggaa aaatcagtta tgaactttat ttggtgcatt tcccagtatt
     3961 gattgctctg acaaatctat tcaaacatca ccattggaaa tatttggata tcgcaggtct
     4021 attcactgtg tttttatgta cattactcat gattacttgc tttagaaaag gagtgcaaaa
     4081 gatgagatca cccaaaattt ggacagctat ggcactaatg ataatcggag tttctgtact
     4141 ggtattacgt gctcctgcca gtcgactgac cgctgaccaa aatcagttgc aaagtttatt
     4201 aaaagaaaac tctagtaaag caaatgcagg agaaaatctg ttgtcacaag agaagaaaat
     4261 attatttatc ggtgattctg ttatgctggg ggcgtatcag gaactaaagg agacatttaa
     4321 aaaagaagca ttggtagatg caaaagaatc aagacaaatc actgcgttac cagaaatctt
     4381 aaaggagcat aaagatttag tttcttacca acaaatagtg atcgggttag gaaccaatgg
     4441 tgtgataaca gatgaagcta tagaacaaac aatgtctttg ctgaaagata aaaaagtata
     4501 ctgggtaaat ataaaagcac caactggctg gcaagatacg ataaatgcca cattagctac
     4561 attgccaaat cagtattcta atataacgat gatcgattgg tatagtgaga gcaaaaatca
     4621 tcctgaattt ttttatgatg atgaaaccca tttgaatgaa agtggacgta cagcttatgc
     4681 aaagtatatt gcttcagtta ttcaataagg tagtgattac gtgtgttaac cttacttttt
     4741 cctaataggt gaatcaattt aaataaaaaa tacttcatat gataaacggt gtttaagagg
     4801 aggagctttt taatattcgt ggtaaaaaag agatgggcga ggtcgttaac tgagagcttc
     4861 ttggaaagaa atcgctttgg atttatcctc tttgttatac agaacatgag cgagacgaca
     4921 atactaggat gtatgttctg atcgaagttt tatggttaca agcagcaatc agcttagata
     4981 aaattaagga tcgtaggaac caagtaaaga aggctgttag taaagaaaca aacgatcaag
     5041 tatgttttac tcttaagaag atgcagtgaa taaataatag taatataatg ctagaaggga
     5101 ctgtgacaaa agacgtgtca cagccttttt tgttatttta attatcgtcc agtctttttt
     5161 tataaatgat tgcttaagca ttaaatatta aaaaatatag agttcaaaat tactgcacaa
     5221 ttagatgaaa aatttgaaca acaaaaagtg tatttttata ctataatagc ttttgaattt
     5281 agttactcta ttcaaaagtt atgctatgga caagaaaaag aataaataga ggtgagaaaa
     5341 tgaatagttt caagaaaaaa tttgtgagta gatttttaaa tatgaaaaat ttttttgaaa
     5401 aaaagggaga ttatgatgca tataattatg tattaaatct agaaaagcaa acatattata
     5461 cactacgtaa aaacgatgat aatgactttt ggactatgtt acctaaaatg ctttcgattg
     5521 actctaagct ttccctttta gaggaattta ttaatttaga cattgaagaa ttttgcgggg
     5581 gaaaagagtt aattaatatg gtagagagtg attatcatac ctattataaa gaaagttgtg
     5641 gatacaaagt ggatgagcaa tgtccacaat caattatttt ttacattgag taatatgaac
     5701 tattaagcag gaaagcaact agaagctact gatttagtat ttacaaatat aaactatatt
     5761 gctaacaatt attttctaga aggaataaaa gaactaagaa tcaagacgtt atcttgattc
     5821 ttagttcttt taacatggaa aagatggata atgcactgtt aattcatgat gcatcatcag
     5881 aaaagttgga aggagaagat agaaatcatt aaatgatttc tacagatggt aaatgaaaaa
     5941 acaaaatatt agcaaaaatt tgcctaaata gatagtaaca ctttctaaat taaatacaag
     6001 cgcattcata aaatgtttat acaaatatct atgtgataaa aattggatat gttcacaata
     6061 aataggaatt aaaataacga atttacgttt gtttttattt accaatcaaa ttatcttaat
     6121 gcaggaataa aaaattaaat tacatattgt taatcattta catctccatt aataactcaa
     6181 aatgaaaaga tgtttttatt tttattctat atttcagaaa aaaattaaac tagattataa
     6241 taattcttca tgtaaaaata aaaacaatta cagctatgat gtttaagata aaacaattat
     6301 gaaatcgata tccgtttata tacttatcat aagctagaag caaataacta gcctatgtat
     6361 gtaagtgaga ttatatttat taaaaggctt cttttgttcg atcagttata gtcgaacgag
     6421 agaagtttat tctttgatta aaataaacaa aagtaactta ttgaggtgaa atgatgcaaa
     6481 cttttttaac taaaacatct ttcaaaaaag tagttttatt agattatttg ttagaaaaag
     6541 acaattggtg tgcaatggaa gaacttagaa atttacttaa tgttacggag aagtcagtct
     6601 tacactatat agaagaacta gaggatttat ttaagcaata taatggtaat atccttctga
     6661 aaaatgaaga taataaacga tttttcataa aaaaagagaa agattttcct atttataata
     6721 tttatcttca tttttataaa gcttcttata attatcattt gattgatttt atgtataaat
     6781 atcctagaag tgttctaaaa gattttgcta aagagcaatt tactagtgta tctactgttt
     6841 tcagatatgc gaagctctta attccatatt ttaggcgtta tcatataaca tttcatccat
     6901 ttcagttaga attgaatgca tcagaggcaa acattcgtag ctttttttat tatttctatt
     6961 ggaattctac acgtgaaagt agtgataagt ggccatttca tatcgaacaa aaggaaatag
     7021 agaagtatat agttgctttt gaggggattt atgatattac gttaactatt tttcaaaaac
     7081 gtgtattttc tttttggtta gccattaata tagaaagaag ttcatttaga aaagtacgag
     7141 tagataatga atataaatca gttatctcag atgatccgca ttttaatctt ttgaagaagt
     7201 ggtcaaaaca aatcaatctt tcttttaaca gcgatgaact gtgtttcctt tatcgaataa
     7261 tttattcttt tggagtaatt gatggaaatg caatatatga aaatagtcat gcatatgcac
     7321 atcagcgaca aaatacttgt tcttatcgag cagttgagaa tttggagaaa gttttacaaa
     7381 gcatgttccg tttttcttta gatataaagg atccagaact catattcaat tttattgcat
     7441 ttcatgaaag aagttatcta ttttatggta atccagatct tttttttaat cgttcgtata
     7501 tcgaagaaat gaaagaagaa gaacctcgaa cttatcacat aatggaaaaa ctcaaaaaag
     7561 aattacaagc aaatgcggat ttggatgtat caaagaaatt agaaaactgg gcacaattat
     7621 ttttggatta ttattatgtg ttagattatt atgatttatt tttaacaaat gttaaaccga
     7681 ttaagattt
//
LOCUS       DAZULR010000087         7614 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.092, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000087 DAZULR010000000
VERSION     DAZULR010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7614
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.092"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            69..1496
                     /locus_tag="ACG8ZV_002592"
     CDS             69..1496
                     /locus_tag="ACG8ZV_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4997853.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(1588..1953)
                     /locus_tag="ACG8ZV_002593"
     CDS             complement(1588..1953)
                     /locus_tag="ACG8ZV_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HFS4997854.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(1950..2315)
                     /locus_tag="ACG8ZV_002594"
     CDS             complement(1950..2315)
                     /locus_tag="ACG8ZV_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HFS4997855.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(2507..2755)
                     /locus_tag="ACG8ZV_002595"
     CDS             complement(2507..2755)
                     /locus_tag="ACG8ZV_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997856.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            2754..2882
                     /locus_tag="ACG8ZV_002596"
     CDS             2754..2882
                     /locus_tag="ACG8ZV_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HFS4997857.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            2939..4633
                     /locus_tag="ACG8ZV_002597"
     CDS             2939..4633
                     /locus_tag="ACG8ZV_002597"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050151 - oleate hydratase activity
                     [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HFS4997858.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            4700..4906
                     /locus_tag="ACG8ZV_002598"
     CDS             4700..4906
                     /locus_tag="ACG8ZV_002598"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997859.1"
                     /translation="MFLIWLDLLPQMQAFEHRLPRGYEKAALHQVIRAAKLKQLLMFL
                     TWLDLLPQMQAFEHRLPRGYEKGV"
     gene            5284..6417
                     /locus_tag="ACG8ZV_002599"
     CDS             5284..6417
                     /locus_tag="ACG8ZV_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HFS4997860.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            6448..6768
                     /locus_tag="ACG8ZV_002600"
     CDS             6448..6768
                     /locus_tag="ACG8ZV_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HFS4997861.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(6797..7261)
                     /locus_tag="ACG8ZV_002601"
     CDS             complement(6797..7261)
                     /locus_tag="ACG8ZV_002601"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4997862.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(7393..>7614)
                     /locus_tag="ACG8ZV_002602"
     CDS             complement(7393..>7614)
                     /locus_tag="ACG8ZV_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFS4997863.1"
                     /translation="VSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAA
                     VNLVLSILIYLPFVKVATIQERRKEALDA"
BASE COUNT         2492 a         1468 c         1371 g         2283 t
ORIGIN      
        1 tttcaaaaag aaaacatgtc ataatatttc ccatattgtg caaaaaaata caaggcggag
       61 gctctactat gattgaagaa tatattgaga aaaatatttt aagacagctg tttttatgtg
      121 ggcaattcta tgtaaataaa gaagtcaatc tagaaaagct ctccaatctc ctgcatgttt
      181 gcaaaaccac tttactcaat gatatcaata acataaaaaa agaatttgaa gaacagatcg
      241 cttatacaca tcgggaaaag gaccgttaca ctttatattt ttcagaacat atacctcgat
      301 gcaagatcat gcagcaattg tctcaaaatt cgttgttttt aaaaacttgt ctgctttatt
      361 tggaagaaga tgaacctgat tatcttcaat taactgaatg tgaattcatc tctgtcagca
      421 aagcttattc attaaaaaaa caagtattag cttattttaa tgactgcggg atcgaaatcg
      481 accgctactc ccctcgattc actgaaatgg aaagacgtct gctgcttctt aatgtgtcgt
      541 atcgtttagg cggttttaat tcttgggagc tacctgaatc gttttttgaa cgtgccgatc
      601 gtttcattga atccgtaacg gaaaatagtg gcagatttta tgataaagaa aataaagaaa
      661 tcttatcgat tggttttgct atcagtttcc tacgccagca agtgtgtgct gtgacaatag
      721 attcaaaatt tatcgaagaa atcaaaaaac gtcctattta caattatgtc gaatcagcat
      781 gggaaaacac tgatttccaa acctattata aaaaagaaga attcgccttt attttgacac
      841 tattcaatct ttgtaattat ggtttccatt cttatcagtt gattgcggaa gactttcaac
      901 agctacacca agtgtttatt gacaatactc ccgaaataaa agaactagtt gctacctttg
      961 aatctcactt caatcaagaa ttattcggaa accaaccgtt cgaacgtgcg ctgattcatc
     1021 tgatgcgttc ggcttgggat aactatcaat tattcatgcc agaaaaattt tatcttttaa
     1081 atgaggaaca gacaaattta tataaagaag tccagacaat tttttccagc tggtccagcc
     1141 agttacctta tgatctacgg ttgaatccta attgcatgcg ggcttttgtg atcgaattga
     1201 gcggaattct ccgtctgaca aaagaacatc tgactatcta tatcgtcaca aattcggatg
     1261 ttcattatct gatttatcgg gaagccttgg aagctgtaac tactttcgat tttcaagttg
     1321 caccaacaat ttattcaagt atatctgata taaagaagta tgcgcagcag tcctcaaacc
     1381 gggtattatg tgaacgtaca ttatatacac cagatgcggt ccaatatgaa aatattattc
     1441 ctatttcgat caatacgatc gatcgagcta tcatttcagc tgtgcaaaac aaataagggg
     1501 ctgtgacaaa aatcatgtca cagcctctta tttgttgaag atgcccattt ctgtaacaat
     1561 ctcttgatac acgtcaggct cacaacctca cttattttgg acatctacgg gtccgatctc
     1621 tttatttaaa aaataagaaa tgatggttcg gataactacc aacgccgcta gttggaaaat
     1681 atcctgcaag gtaggtttga taatcgattc gatgatccca gctgaaacaa gaatttccaa
     1741 acttagaagt atatagcctc ccaacatctt tttaatagca ttgttctcgc tgactcggtc
     1801 gctttgcact tttgtatgga caaataaata tttcaaaaaa tccttgattg atagacaaac
     1861 accccaaacc aataaacaga tagcaaagat atcaagtccc agtacaagtt tttcgaaata
     1921 tggaagaaga aactgcatca actctgtcgt catcctacct ctcctcttct ttgtttttct
     1981 ttgtcttcta tttcctgatt caagaaataa gaaatgactg ttcgaatgat aataataagt
     2041 gcaagcttca aaatatctgt ccaagtcggc ttgataactg actcgatgat atcagcaacg
     2101 actagtactt ccaagcttaa caaaatataa cttgctagca gttttcttgt atctgcatta
     2161 cgagtattac gttctgcata gtttttcttg acatgagacc aatcaaaaag tttgaataga
     2221 acaagaacga tcccgacaat taagataccg atagaacaaa tatttaaaat agcaatgatc
     2281 cattctagaa attcaattaa atttgagcga aacatatacg ctacctactt tcttttaatt
     2341 tgttcctatt cttttattgt aaaagaaagt taccttgttc gtctatttaa aagttgttct
     2401 aatgataacg gttcgcttaa atttttcttt ttcactctcc catttttctc cctccatcca
     2461 taaatcgtgg aagtatccaa aacaacgtag caagttaaaa taaggcttag tccgtcatca
     2521 gcttttcaaa gaagcactgt ctcggtgctt tttttgtacc caaatttcta aaaatagaac
     2581 catacacctc ctcaaatctt ttcttcttac ctaccctatt tttatttaca ggaaaatcag
     2641 acacttcttc ttttttgtca aaatttcctt tttcttctcg tcctatcatt tggcattcta
     2701 ataaaaacga actatccttg gatatagaaa gagaaaacaa ggaggcgttt ttcatgagta
     2761 aaaaattaat caaagtcggc atcggtttag gtttgcttgc ccttggcgct gcatatctag
     2821 gaaaaaagac aggactattc gaagatgaca gtcatttata tgatgaattc gaatcaatct
     2881 agcatcctat ttagttgaat cactacggac atacttggaa gacattggag gaatcacaat
     2941 gagaaaaagt aaagcaataa tgattggtgc cggtattgcc aatatggcag cggctgttta
     3001 tttgattcaa gaaggcaaat ggaaagggga tcagatcacc ttttattcat tggatgatca
     3061 cggttcaaat gatggtgcac cgaccgacac tgtagtggat gaatattgga ataaaaacca
     3121 tccattagaa aaccaaaaag gctatattgc tcgaggcggt cgcatgctta attaccgtac
     3181 ctatgtagat ttgatggatc tgttaagtcg aataccttct gttactgagc cagggatgac
     3241 tgctgaagaa gatacgagag attttgatgc aaaacaccga acctttgaca aagcacgttt
     3301 gatggaaggt ggcaaaggaa tcattgatgg cggaaaactg ggattcaata ataaagaccg
     3361 tattcttctg actaaactga ttgctatgcc tgattcagaa gaagaaaaac tagacaatat
     3421 cactatcgaa gaatatttca aagatgatcc acactttttt gaaacaaact tctggtttat
     3481 gtgggaaaca acatttgctt tcagaacacg tagttctgct caagaattgc gtcgctatat
     3541 gcatcaaatg atttatgaat tcactcaaat cgaacatcta gtgggcgtca atcgaacacg
     3601 ttacaatcaa tacgaaagta ttatgcttcc tttgatcgag tacttgaaag aacaaggatg
     3661 caaaatcatt ttgaaccgcc gtgtcactga ctgggaattc aaagaaacac cgatgcaaga
     3721 tgaaatcact gtgactggtt tgaaaattac caatacactg actcaagaag aagaatacgt
     3781 tgtggtcgat gaagatacag cagttatttt cactaatggg tccattacag attcagctac
     3841 tttaggagat tacgaaacac cagctgtaga aaatatggat tatggtgcag cttctagtct
     3901 ctggaaaaaa gccagtgaac gtttctacaa cttgggaaat cctgacaaat tctttgctga
     3961 tcgagatgca agcgaatggg tcagctttac cctgacgacg aaaaaccatt tgttgttgaa
     4021 tgaaatcacc cgtatcacga ctcaagaacc aggaaatgcc ttgaattcat ttatttcaac
     4081 cacaccgatc acgccgttag gccaaaaaga tgtcaatatg tctattgtcg tgcatcatca
     4141 accgcatttt acgtctcaga aaccaaatga aacagttatt tggggttatt tcctttatcc
     4201 aagacgacgt ggcgaatttg tggataaaca gtatattaaa atgaatggaa aagaaatgct
     4261 agaagaactg attggacaac tttcaaaagt agatcctgga ccagtgaata ttcgtgaaaa
     4321 agaaacagaa attttcgaca gcgtaataaa taatatccct gtctatatgc cttatgcttc
     4381 cgcgttgttc aataatcgtg ccaaaagcga tcgaccaaaa gtcattccta aacattcgac
     4441 caatctggcc tttacaggag aatttgtcga gcagccttat cagatgatct ttactgaaca
     4501 aagtgctgta cgttctggag aaatcgctgc tttccatttt gcgggtattc ctatgtcccg
     4561 tcttgtcaaa acaccgcgtt acgacaaaga tattcctact ctagctcgtg ccgcaaaaaa
     4621 aatgtttgaa taatcaagag gttgtgaaaa agctgccctg catcaagtaa taagaacaac
     4681 caggctaaaa cagcttctta tgtttttgat ttggttggac ttattaccgc agatgcaagc
     4741 ttttgaacac cgtttaccaa gaggttatga aaaagctgcc ctgcatcaag taataagagc
     4801 agccaagcta aaacagcttc ttatgttttt gacttggtta gacttattac cgcagatgca
     4861 agcttttgaa caccgtttac caagaggtta tgaaaaaggc gtttagtttc gagtatgaag
     4921 aaaaattttg tgaaaatggt tcctcacgtt tttgcataaa tttgacttaa taccgagaaa
     4981 ctgatccctt ctgtcataac ctctttttat ttatgtctgt ttctttttga aaacaactat
     5041 tttttcaacg tttactctct tgccaatcca acatcatcta acggatacaa ctatttcaat
     5101 gattaccatt acactaaaaa atcggaaaca cacctctccg aacacaaata cataagacta
     5161 tagaatgttt catttaagaa aaaaagcgtt tcattatcaa aaaggtaaga tctcctttaa
     5221 aatgaaatta tctgtagtac taataatgca gacaatttta tgaatctgaa aggagcatct
     5281 ccaatgaaag cagtcacttg gcaaggaaaa cagaaaatgg aaatcagaaa cgtagatgat
     5341 ccaaaaatat tagaaccaac agatgcaatc atccgtatca cagcaacagc catttgcggc
     5401 tccgatctgc atctttacca tcatggtgaa gcagttttgg aaaaagggta tgttgtagga
     5461 cacgaaccaa tgggaatcgt tgaagaagtg ggatctcaag ttcaaacatt gaaaaaaggg
     5521 caacgtgtgg ttatcccttt taatattagt tgtggtcatt gtcatttctg cctgaatcac
     5581 atggaaagcc aatgtgatga atcaaatcca gatcagttat atggcgggct tttcggattt
     5641 ggcaagttga acggtaatca ttggggtggt caagcggaat atctaagagt tccttatgca
     5701 gactctactt catttgttgt accagataat gatcttcctg atgaaaaagt tttatttcta
     5761 tcagatattt tgcccacagc ttattggagc gttgaaaacg caggagtaaa aaaaggcgat
     5821 acagttgtga ttctaggttc tggtccagtc ggtctattcg ctcaaaaatt cgctgttatg
     5881 gctggagcag agcgcgtaat cgcagtagat ccagtacagc accgtctaga taaagcggct
     5941 aattacaatg gggttgaaac ttatttctta gaagacacgg cacaagctgg aacagaattg
     6001 tatgaactgg ctaaaggtgg cgcagatgtc attatcgatt gtgtaggaat ggacggatta
     6061 gagcctgtca aagaaaaagc gaaaaattta gtaagcttac aaagcggcac aatctctcca
     6121 ttacagatgg catcgcaagc tgtcaaaaaa tttggaacag tccaagtaac tggtgtttat
     6181 atgactccag cttcttctta cccgctgcaa gaatttttta tgcgggatat cgctgtcaag
     6241 catggacagg caccaattat ccatctaatg ccaaaaattt acgcaatgat tgcagaagga
     6301 ctattcgatc ctacacaaat cattactcat tcgctgccac tatcagaagc agcacaagca
     6361 tatgagatct ttgacaaaaa agaagataaa aatataaaag ttgttttgaa accttgaatt
     6421 cagtaaaaaa tacaggtgat tttctttatg cccaaaatca aacgaaatac ccatgagatc
     6481 gaaataggaa aagaagaaga tatcgaaata cgaggacgtc gcttccgctt ctatttccaa
     6541 aatcgttaca cattgatctc actggctgtc gatttattaa ccgggatttt ctatattttt
     6601 ggaagccttg cttccttaac taaaatcccc gatcgatatg gcacctattt ttatttggct
     6661 ggtgctattt tcttgacgat tcgtcctatt ctcagaatcg taaggaacat ttttatttac
     6721 gacgaaaaaa aagcaatgaa gagaacaagc aaaaaaaaag aggcatgaga atttttcaaa
     6781 tctcatgcct cttttttcac cctatcgtat cactttgata cagacgagcg gtcgtcccac
     6841 tttcttcctt gaccattgtc aaaaatgtcc actcgtatcg ttcataaaac gtggtatgat
     6901 ctgtaattaa gtaaagtttt tcgtacccaa gttgatgcat ttcttttctg atttccgcta
     6961 atatccgctt ggctatcccc tgcttacgct tttccggttc aacaaacagg gcacaaagat
     7021 ttggtgtcag atcagggcgg ttatggaagt cgttttcaat gacgcccgct cctccgacga
     7081 tggtttcttt ttcatctaag accacatacc attgaggaat actttcctta ttagcgattc
     7141 cagtacgaat actttcctca tacacaacag caggaactcc ccattttgat gaaaaccaat
     7201 tcgcgctttg ttttactaat tctgggtgtt ctcttaattt gatccagtta tatgtaacca
     7261 atgtttaaac ctccgactaa aataaaacgt ttacaaaaat tatacaagtc tttatgaaaa
     7321 ttagcaatga caacaatagt gatgtaaaaa aaaaaacgga aaacaatcac ttgttctccg
     7381 ttttttgatt aatcaagcat ctaaagcttc ttttcttctt tcttggatcg tagctacctt
     7441 gacgaacggt agatagatca aaatagaaag aaccaaattg acagcggcta gtacaccacc
     7501 tgcaatactt tttgttgcca atacaccgcc aataattggt ggagttaccc atggaggcat
     7561 aacggtagct gctggcacta aacctgtaga agtcgcaaag taagcaacac taac
//
LOCUS       DAZULR010000088         7600 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.093, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000088 DAZULR010000000
VERSION     DAZULR010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7600
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.093"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(138..428)
                     /locus_tag="ACG8ZV_002603"
     CDS             complement(138..428)
                     /locus_tag="ACG8ZV_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997864.1"
                     /translation="MGEKKIKGAGILLVMSKALFLLPCTFMFIVLCYFKRRKKWCWID
                     VLLFLPFFPLIYFLEEIWDDMACDSAFLFSHSLGLMISLTIFAIVLFFLNKK"
     gene            complement(546..806)
                     /locus_tag="ACG8ZV_002604"
     CDS             complement(546..806)
                     /locus_tag="ACG8ZV_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997865.1"
                     /translation="MGVDHLIVLSKLLFWIPFIIMTSAFFYLFKRPNKYLLLSACPMI
                     YFIHKIRGFYYYDSGISLFCYEIGLLASAIFFIFVLEYFRKK"
     gene            complement(943..1356)
                     /locus_tag="ACG8ZV_002605"
     CDS             complement(943..1356)
                     /locus_tag="ACG8ZV_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HFS4997866.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1812..2297)
                     /locus_tag="ACG8ZV_002606"
     CDS             complement(1812..2297)
                     /locus_tag="ACG8ZV_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997867.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2436..2651)
                     /locus_tag="ACG8ZV_002607"
     CDS             complement(2436..2651)
                     /locus_tag="ACG8ZV_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HFS4997868.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2875..3675
                     /locus_tag="ACG8ZV_002608"
     CDS             2875..3675
                     /locus_tag="ACG8ZV_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFS4997869.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3694..5562
                     /locus_tag="ACG8ZV_002609"
     CDS             3694..5562
                     /locus_tag="ACG8ZV_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HFS4997870.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5555..6046
                     /locus_tag="ACG8ZV_002610"
     CDS             5555..6046
                     /locus_tag="ACG8ZV_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HFS4997871.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6034..6588
                     /locus_tag="ACG8ZV_002611"
     CDS             6034..6588
                     /locus_tag="ACG8ZV_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HFS4997872.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6606..>7600
                     /locus_tag="ACG8ZV_002612"
     CDS             6606..>7600
                     /locus_tag="ACG8ZV_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HFS4997873.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2707 a         1213 c         1443 g         2237 t
ORIGIN      
        1 tttgttacta tgaataacat aataagaaag taaagtggat tgatttgaga tctttttata
       61 cttcaaaaaa gataacaccc aactttcaaa aatatgtttt ggaagttggg acaaacgagt
      121 taatacattt taatacatta ttttttattc aaaaaaaata gcacaatggc aaagatcgta
      181 agagagatca taagccccaa tgaatgacta aaaagaaaag cagaatcaca tgccatatca
      241 tcccatattt cttcaagaaa ataaataagc gggaaaaagg gaaggaatag tagaacatcg
      301 atccagcacc atttttttct tcttttgaaa taacataaaa caataaacat gaacgtgcag
      361 ggaagtaaaa acaaagcttt actcataact aacaaaatac cagctccttt tatttttttc
      421 tcccccacat tcaaagagta acaatggtat gtacttaata atagaaaaat ggatcaactt
      481 gtatgaataa cagctgaaaa gatctgcacc aaataaaaaa cttccagcca aaactgactg
      541 gaagtttatt tttttctgaa atattctaac acaaatatga aaaagatggc cgaagctaat
      601 aagccgattt cgtagcaaaa caatgagata ccagagtcgt aataataaaa tcctctaatc
      661 ttatggataa aatagatcat cggacaagca gataagagta agtatttgtt aggccttttg
      721 aataagtaaa agaaagcact ggtcattatg ataaatggta tccaaaacaa aagtttactt
      781 aagacaatca aatgatcaac tcccatattt tttaccaaga gagatcataa catctttatc
      841 gtaaaaacaa aatatttttt tgctcatttt gaaaatttaa acatactcgt tcttatccaa
      901 atatataaaa atcgcccctc attcatcgag aggcgataag ttctaattta actcaatttt
      961 ttttgtttct tttggctgat aagctgtttt aggtaatacc aatttcagca caccgttttt
     1021 aaaggttcca gtgatttttt cttcatcaac attaggaaga tagaatgaac gtttgtaaga
     1081 gaccgaatgt ctttctttcc gtacatagtt gccatcttct ttatcttctg tatgggactc
     1141 atgattggcg gagatcgtca aagtattatc tgaatattca actgtcgtgt cttctttgtc
     1201 acagccaggc atatcagcag ttagtttgta ttctttttca ttttcgacta aatctacttt
     1261 tggataactt gaaacaccta aaaaatcatt gaatgctgga ctaaacacgt cattgaaatc
     1321 agggaacatg tcgcgaatgc taggtacatt tgccattttt gatcatcctt tcaataagta
     1381 ttttttattt atccctattt acgtaataac tctattttga aaaaaatgca agtataatgg
     1441 ttagctttgt gaatatttca tctaatacga tacaaaggct atctttctaa tttgaaaaag
     1501 ggatcattaa aataataaga agaaaatatg tcaaaaggta aaaaagtaaa ttcttctatc
     1561 caaatataga aaaattgaat ctagaaaacc gcccgacaat aaatttcatt aactcagttg
     1621 accgaaaatg aagtagatac caaaaattta tcaagagagc aagtagagaa gtgagtatat
     1681 tcataagaga aatagctgta acgaattatt aggttaatgc aaatgcttat ttatactccg
     1741 tataactttc tcagaaaaaa tgataccaat aatgacttgc tagtactgta aatccgtata
     1801 atatcatcta atcaaaatgg tgttccattt gcatctgtca tcgtaatcga tccttcgggt
     1861 gacactcgat aaaaaccaac gcttccagat cctccttggg aacggatttg tttgctggaa
     1921 gctgtgaaca aataatctcg atcaattttt tgataaaagc taataacaat atcgtcactt
     1981 tgtaattcgg aacggtgggc aataagaaat agaagtgctt tgtcagagtt ttctaatgga
     2041 agagaaggta cagtgctttc ttgcatttca gatgttgaag aaatgctaaa cgactgaata
     2101 cttgattggc tatgttgcga atctacatta ccagtagaag tattagtaat ggaagtagta
     2161 gaagtacttt tagttgaacc aacctcagtt gttgaaatgg ctgctgaaga ttctttaaca
     2221 gaattctttg ttttatatcc acaggcagaa aaaagtatta cagttcccaa caagcctgcg
     2281 taaatccctt tatgcatgat agctcctcct aaaatagatt atctttattc agtatatcac
     2341 ttaaacaaag aaaagcagat ggtttaaaat gaaaaaacct tcccaataaa gggaaggttc
     2401 atgaagataa taactttttt aataattata gctttctaat atctttcatc aacttttcta
     2461 gtaatcattg ggaaaaattt caagcagtag atcgcacaaa tacctacgac gatataaatg
     2521 atcttcgcaa aaatagttgt tgaaccacca gcaatcatag ctactaaatc aagttcgaac
     2581 aagcctacca acagccagtt caaccctccc acaatcaata aagttaatgc aatagcatct
     2641 aaagttttca ttagaattct cctttcttaa atgataaaac aattatatat caaaaagaga
     2701 aacattgctt atataacgct caggaatttt agcaatctat gcaaaaagat gaaaattttt
     2761 tttgctcttc cattagtaca cattttttag ctgaagctgt aaatttcatg tcttaatttt
     2821 ttttagtgag cttttatact ggatttgtaa gaaaaaagaa ggagaggatc acatatgtcg
     2881 gattggttgg atattgcagg aaaagtagta attgtaactg gaggttcctc aggaattgga
     2941 agaagtatcg tcgaaaattt gttgaagcag aatgcacaag tagcgaattt tgatgtaact
     3001 gaatgccgta tacagcatga aaacctacta tctttaaaag tcgatgtgtc ttctaaaacg
     3061 gacatagaag aagggatata taaagtaatg aaacatttca agacgatcga tggtctagtc
     3121 aataatgcag gaataaatat tccttctctt ctaatagata gaaatcatcc aaaaagcaag
     3181 tatgaattat cagaacaagt ttttgataag atgatcgctg tcaatcaaaa aagtgtatat
     3241 ttgatgagcc aagcagttgg aagaatcttg gtgcaaaagg gatcaggagt gatcgtgaat
     3301 ctttcttctg aatcaggatt ggaaggatca gaaggacaga gctgttatgc tgctacaaaa
     3361 gcagcgatga acagttttac tcgttcttgg gcaaaagagt taggaaagag gaatgttcgt
     3421 gtggtaggtg ttgcaccagg gatactggaa gaaaccggtt tgagaacaca agaatatgaa
     3481 gaagctcttt cttatacgag aggtataagc gtcgaacagc tgagaaacgg ttacagtcga
     3541 acaagtacga tccctctagg aaggagtggt aagctgcaag aagtggcgga tctagtctgc
     3601 tattatcttt cagaaagatc aagttatatc actggagtca cgactaatat ttcaggaggt
     3661 aaaacaagag gataaaggat aggggggacg cacgtgacgc tagtaaacag atggtaccaa
     3721 ttattgaaat tactagtcac tcacaagaaa gtttcaatcc aggaagtgca aaaagaaatc
     3781 aaaaccagta atcaaaccat aaaaaaagat attggggagt tgaatgaaga aattgccggt
     3841 attgcaaaaa tcatccaaaa aaacaaacat tttgaacttg aaatttatga ttttgatttt
     3901 tttgatgaga tcatgcaagg aaaattgaaa acagccagtg atttcaattc ggcatccaaa
     3961 agaatcgctt atttactaaa taggctgatc gaaacagagg atttcttacg tatggatgat
     4021 ttgtctgaag aagtcggtgt cagcagagga acagtggtca aggatctaaa gacattaaaa
     4081 gagatgatca atgattttga tgtaaagatt acaggcacac caaataaagg actaagaata
     4141 ataggagatg agctagaatt acgactactt ttattttatt ttgtttctcc ctacttttca
     4201 gagacgaaaa cagaacagtt tctagaagaa aaacaagcaa tcaaacattt tcagaagaag
     4261 acgaatgcta gtaaacaaga aatcaccctt ttaacgaaag ttatcggtat ttctttgaat
     4321 agaatctcta gtaactatct gttgaagaag cccatcaatc gttacagtgg gtgttttgaa
     4381 tatatccaag aattcaatga actgatcaat cagttggaag aaatctatga actaactttg
     4441 agccaatatg aaaaagattt tatcagtttt cctttgaaca tcatcaacac aagtataacg
     4501 atgataagga aagctaactc tgatttgcgc ttatatttcg accccatgat gatgcgtatt
     4561 cgacgattag atctcattga tctggatgag tccttcttat atcaagagat gaaacagcac
     4621 ctctctttat tgataaatcg ggtaattttt cgttatcgat tgactgattt attttatggt
     4681 gagatagaaa aaaagtatcc tttttcttac caaatcgcta gcgaatgcat acaagcatta
     4741 gaagctatct tgcaacataa gatctctaaa gtagagatca gctacctaac gttgtatttg
     4801 gagttagcat ttcgatatca aaaagagcat ttttcctcta aaaaagtagc cattgttcat
     4861 acgacaggaa aaggaacagc attaatgatc caaagacaaa tcaaaaggat attggggagg
     4921 gatatacaaa taacacatgt ttcagaagaa caatatgaaa aagtagatct aaacaaatat
     4981 ttcgctgttt ttacaacgat tccgttaaaa aatgtaaatg aagagacacc ggtgatccat
     5041 ttgactaatc tttttgatga ctcttggtta agggcacaat ggcaaaaagc aaaaaaaaag
     5101 cgattagccg ggtttcattc tactgttttt ttctatcaaa tatggaaaga aaaaaagacg
     5161 tatcaagaat atttaaacaa attagtcgct cctttgatca gaggctatta tgtggatgaa
     5221 gaatttgaaa aaaggatctt gaaaagagaa tatcagcaaa gcacatttgt taacaaagaa
     5281 tttgcttttc ctcacacaac caaccagcta tctcaacaca ttgttttatc agtagggcta
     5341 ataactgatc aaggtttagc agaaacagga ggaaatggag ttattttttt atttgccata
     5401 cctgaagaaa tgacggctga agttgagaat gaattatttg agctatacga tatcctattt
     5461 gaactcataa aaatgggaat agatgagttt attgaattag caccgacaca agaatcattt
     5521 ttaaaactaa tcaaaagtaa aggagagaga cttcatgaat gatatgtatc tattcatagt
     5581 tttcgcagct tcagcttatg tgctgcaagc agttatcagt tggaagcaac taaagcattt
     5641 caatcaaaca tatagcgaac tgcgaagaaa aggaaaagta gcgattggta aacgacctgg
     5701 gaaaatccgt tcaggcacga ttgttatgct agctatagac gatcatgatc aagttttaga
     5761 agtcagaaaa atgcaagggg ttacatcttt ggcaaaattt cattcattac ctgtctatgc
     5821 gggtgaagat atccattaca tcgatcgtta ccatccctca gttcgagcgg aagatcgttt
     5881 gacacaagca gctttagaaa atgccagaga agtatactta cgaatagagg caggaaatga
     5941 aaaaagtgaa caaccttcat tgccttttat tgctatgctc aataattttc ggatatggaa
     6001 aagtacgatc aaagaaaaaa ggagtgacaa acgatggata tcataacaaa atttgctgag
     6061 ggatttatga ggctgttcca aacaggtgca gaaacattca taagctggat gacaggaatc
     6121 gtaccagttg tcttgatgct gatggttgca atgaatacgc tgattgcttt tttaggtgaa
     6181 gaccgagtaa cgaaagtagc caaattatca gcgaaaaatc cgcttactcg ttaccttgtg
     6241 ttaccgttct tatctgcttt tatgttggga aatcctatgt catttacaat ggctcgtttc
     6301 cttccagaat actacaaacc aagctattat gctgctcaag ctcaattttg tcatacgagc
     6361 aatggtgtat tcccccatat taatcctgga gaattgtttg tatggatggg gattgctcaa
     6421 gggatcgaaa ccttagggct aaattcgatg gagctggcta tccgatactt gcttgtggga
     6481 ctgctgatga actttattgg tggttggata actgatttta ctactggatt tgtatgcaga
     6541 cagcaaggaa tcgttcttag caaaaaagta gagctttcag ttgattagag aaaggagagt
     6601 tttaaatgta tggtgatatt aagatcgtaa gaggaaacgg cgggtatgga ggtcctttga
     6661 ttattaggcc gacaaaagat aaacacaagt tcatctatgt cacaggtgga ggtgagaggc
     6721 caatgatcgt agataaaata gaagaactga caggtatgga gtctatcaat gggttcaaaa
     6781 catcaatacc tgatagtgaa atcgcgcttg caatcgttga ctgtggaggg actcttagat
     6841 gtggaattta tcctaaaaaa gggataccaa ccatcaatat cgtttccaca ggaaaaagtg
     6901 gcccattagc acaatatatc actgaagata tttatgtttc agcagtaggg ttagaacaaa
     6961 tacagccact aatggaaact gatgataaca aagaaacagt aaatactgca tctccagata
     7021 aaaagtacaa atatgatact tctaaaaaga taaccgagca aaaagcagag cagcaaaact
     7081 ggatagcaaa aattggaatg ggcgcgggaa aagtagttgc tacattcaat caatcagcaa
     7141 gagaagcagt agatacgatg atccggacag tgatcccttt tatggctttc gtttcccttt
     7201 tgattggtgt gatacaaggt tctgggatcg gtaatgtatt tgctaacatt atggcacctt
     7261 tagcaggaaa tgcagttgga ttaacaatca ttggctttat ttgttcactg ccatttttat
     7321 ctcctttgct tggtccaggg gcagttatta gccaagtgat tggaacattg atcggtgtag
     7381 agattgggaa aggaaatatt cctccccaat tagcattacc ggcactattt gctatcaata
     7441 ctcaaaatgc atgtgatttt attccagtcg gtctaggttt ggaagaagca aaagctgaga
     7501 cagtagaagt aggtgtacca tcagttcttt attcaagatt tcttaacggc atcccacgag
     7561 ttatcattgc ttgggtagca agttttggat tatatagctg
//
LOCUS       DAZULR010000089         7277 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.094, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000089 DAZULR010000000
VERSION     DAZULR010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7277
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.094"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(69..1415)
                     /gene="gor"
                     /locus_tag="ACG8ZV_002613"
     CDS             complement(69..1415)
                     /gene="gor"
                     /locus_tag="ACG8ZV_002613"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HFS4997874.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFCGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(1549..2802)
                     /locus_tag="ACG8ZV_002614"
     CDS             complement(1549..2802)
                     /locus_tag="ACG8ZV_002614"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1901576 - obsolete organic substance
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HFS4997875.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(2808..3731)
                     /locus_tag="ACG8ZV_002615"
     CDS             complement(2808..3731)
                     /locus_tag="ACG8ZV_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HFS4997876.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(3952..6444)
                     /locus_tag="ACG8ZV_002616"
     CDS             complement(3952..6444)
                     /locus_tag="ACG8ZV_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HFS4997877.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(6451..6918)
                     /locus_tag="ACG8ZV_002617"
     CDS             complement(6451..6918)
                     /locus_tag="ACG8ZV_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HFS4997878.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(7054..7127)
                     /locus_tag="ACG8ZV_002618"
     tRNA            complement(7054..7127)
                     /locus_tag="ACG8ZV_002618"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7091..7093),aa:Arg,seq:acg)
     gene            complement(7185..7258)
                     /locus_tag="ACG8ZV_002619"
     tRNA            complement(7185..7258)
                     /locus_tag="ACG8ZV_002619"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7222..7224),aa:Pro,seq:tgg)
BASE COUNT         2006 a         1603 c         1183 g         2485 t
ORIGIN      
        1 cagtatactg attttctggt tttacatggt ttgttcaata aaaagctgtt ggaactgtta
       61 atattaaatt atcgcatcgt tacgaattct tccgctcctg ttggatggat ggctactgta
      121 ttgtcaaagt cttctttagt tgcacccatc ttgatagcca cggcaaaacc ttgcagcatc
      181 tcatcgacac caacaccaat agcatgtaag ccgacgattc tttcttcttt tccgacacag
      241 atcaatttca tttcgcattt ttggcgataa tcatttaatg caaagtacat tggggtaaag
      301 cgtgaacgat aaactttcaa ttcattttcg ccatattttt ccaatgcttc ttcttctgtc
      361 aaaccaattg ttgcaattgg tggatgcgta aagacgactg tcggaacaag tttatagtca
      421 agataagaat ctttctttcc attaaataaa cgttctgata aacgtctacc agctgcgatt
      481 gcaacaggag tcagatctaa tttaccgatc acatcaccaa cagcaaaaat atgttcatcc
      541 gttgtatttt ggtatttatc tactttgata aacccttttt tgtccaattc cacatttgta
      601 ttttccagac ctaatttttc ggtattcggt acacgtccac cggcaaaaag tacacaatca
      661 ccagttaagg tttcaccatt ttcaaatagc accgtatatt cgtcattgtt tttagtaatt
      721 tctttagcaa tatgatgtgc gtaagttttt attccagctt cttggtacat ttggatcaaa
      781 ttgtccgaaa gcattttatc aaacgttcta agtggtcgtt cttttcgata tgcccacatg
      841 acttcactac ctaaaccaca aaatacacct gaaagttcag ccgcaatgta tccagcacct
      901 aaaacgattg ctctcttagg taactctgtt aattcaaaaa atccatttga atcaattgcg
      961 tattctccac caggaatggt cattttactt gcacggcctc cagtagcgat caagatttta
     1021 ggagcacgat aggtttcacc gtttacttcg atcgtttgac tatcgataaa agtagcgtaa
     1081 ccttttatag cctcgacatg attgctatct aatcctcttt gataagcacc gtgtagaaaa
     1141 tcaatatatt tttctcgtct ttctactaga ccggcgaaat caacattttt taaatctgct
     1201 tggataccgt aacttgaggc atctcgttca attgtttcca aaatcgtact tgcttgccac
     1261 ataacttttt taggtacaca accgacgttg acacatgttc cgcccaattc attcgcttca
     1321 atcagcaaaa cttttgcgcc atgcatccct gctctgtttg ctgaagcaat accgccagag
     1381 ccgccaccaa ttacgatgta atcatatatt tgcattttgt tcctccttat tgaagagatc
     1441 aatcaaaacc tttatttaac gatccttttt ctacagaaaa caagtgtaac acttttcttg
     1501 aattttgtat gcgaagatgc ttaaaacagg gatatatcag ctttttcctt atttacgttt
     1561 tcggatcata tctccaggtt tcaccggctg tgcgactggc atagttaaaa tcatcattgg
     1621 atttggtgct cggtcaatgg attcgccttc ttcattatgc ataacttcaa cggtttgact
     1681 gaaatgactg aatcctggac cataaaattc gatttcatct cctacagaaa acaagtttct
     1741 ctgacgtatc gtagcaatct gtgttgcctc atcataagat aatacttcac cgacaaattt
     1801 atatactggg attttacgac gttcaccgaa taattgttcg ttttcagttg gtgtattgta
     1861 gtaaaaacct gtagctaatt ctcgttgtgc tactttccat aactcgtcga tccattcttg
     1921 cttgcagaca tagttttcag gatcttccat ataactgtct acagccgctt tatagacatt
     1981 tgacaccgta gatacataat ggatcgattt cattcttcct tcgatcttga agctgtctac
     2041 gccgttttca atcaattctg gaatatgttc gatcattgac atatccactg cactcatcga
     2101 gaattcttct tccacttcgc ctgtatcagt taaactgttt cgttcttgac caaaaggcat
     2161 atcgaacaat ccatacttcc agcgacaaga ttgagaacat ccgccacggt ttgcatcccg
     2221 catcgacata tggttggaca atgtgcatcg accagaataa gagatacaca tggcaccatg
     2281 gataaatgct tcgatttcgg tatccgtatt tttacgaatc tctgccactt cctccattga
     2341 aacttcacga gctaaaacga cacgttccaa cccttcttct ttccagaatt ccaatgtctc
     2401 aaaattagtt gctgaagctt gagtggataa atggatcggc agacctgggg cttctgtcgc
     2461 acaaatttcg atcaaagctg gatcagaaac aatcactgca gaaataccga catcacgcaa
     2521 actgcggaaa aattcccctg ctccatcttc atttccttca tgggtgacca tattagcagc
     2581 aacgtatacc ttcgcatcat gttcttttgc aaaagcaact ccttcagcca tttcttcata
     2641 agtaaaatta cctgcacggc ttcttaaacc atatgcattc ccgccaatat atactgcatc
     2701 tgctccataa tggatcgcgg tttttaactt ttccagtgtt cctgctggcg ctaggatttc
     2761 tggtcgtttc aattttcttt ttactgtcat ttctttcatc atactcctta tttgatagca
     2821 gaaggatcaa tataaaagaa tcctgtatct aattcacggt tttcaggatg caatttactg
     2881 atttcgctag tcattttttc cgctttttct tgatcccagc taccttctaa aatttgtttt
     2941 tttgcttcgg cgaatagtcg agtgatgttt acgaattttt cgcctggagt aaataatccg
     3001 tccaatttcc atgtacagta atgatgctga taaagttcat tcaattcatt cgagagattc
     3061 agatcattgc tggcaaaaat atgtgtgcca tgactatctt cataaataga ataatgtgtc
     3121 tcttcttttt taggttccga gataaaaaga cctctttcac gatctttttg ttcgtcttgt
     3181 ttcgtatagt tatagtaatt ctgtagcagt ggacgtttgg attgatggat gcatgtagca
     3241 ccatacacaa gggtttctac aggaatatcg agtttttctt ccatcgcctt catctcttca
     3301 aaaggaactt cacgagcaag tactgctcca actgcgcctt ttttcgccca gaaattgatt
     3361 tgacgtgcgc tcgttactaa tgtttcagca tcataaatat acggtatacg caattcagga
     3421 ttttttttca tcgtataaat aatacctgta tcaccaactg tgatcacatc tacgtttatt
     3481 tcttttaaaa aagccaaata ttcaggtaca tttttcattt tttcaggatg aatgatccca
     3541 tttacagcaa tattcgcttt tttaccatac ttgtgtgcta attctaccaa ttgtcgctgt
     3601 tcttctcgtg taaatgaagc aggcagacgc aatccaaatt gctcttcacc gaaatatagt
     3661 gtatctgcac ctgcagcaag caactgttct gcttgttcaa tagtttctac tgtggttatg
     3721 agttcgatca taattttctc ctcctacaac ttcataatag tagcatagct ctaaaaactt
     3781 tccaatactt cttctattta aagtcggatt tttgaaaatt atttcacaaa aaatcaaaat
     3841 aaagttcgat atattctgtc caaatataaa aagagattgt gacaaaaatc ttgtcacaac
     3901 ctcttaatca agtcttacta ttataaaaat tcagctacac aggccaagta actataggga
     3961 acctactgtt tcctttttag gtccgcgaac attcaatgtg atcttacctt ttgaagcacc
     4021 tactgttacg tggtcaccta aacgaatttc tccgccaagc aaagcctcgc tcaatcgatc
     4081 ttcaatttct ttttgaagtg cgcgacggat tggacgtgca ccatattcag gatcaaatcc
     4141 agctttcccg atcacatcga ttgcagatgg tgtgattttc acttgaatat cttgttcttt
     4201 caatcgtttg ataatcgctt tgctcatgat ttggacgatt gtatggattt catctttact
     4261 caatgaatgg aagacgacag tctcatcgat tcgattcaag aattcaggtc ggaaagcttt
     4321 ctttaactct tctaagatac gtttttgcat ggctttgtga tctttagtaa catcttggac
     4381 attgaatccg acattttttt cttctcgaat ttgtgtcgct ccgatatttg aagtcataat
     4441 catgattgta tttctaaagt ccacttttct acctttagaa tctgttaaat gaccatcatc
     4501 caatacttgc agaagtaaat tgaaaacgtc tggatgtgct ttctccactt catctaagag
     4561 aatcactgaa tatggttttt gacgaatttt ttctgtcaac tgtccacctt catcataccc
     4621 tacgtatcct ggaggagacc cgattaatcg gcttgtactg tatttttcca taaattctga
     4681 catatcaaca cggatcaggg catcttcact tccaaacatg acttctgaaa gtgctttggc
     4741 caattctgtt tttccgacac cagttggtcc aaggaacatg aatgaaccaa ttggacgatc
     4801 aggatctttc aatccgcttc gtgcacggcg gatcgcacgt gaaactgctt tgacagcctc
     4861 atcttgacca acgacacgtt catgcagaag tccttccagt tctaacaagc gttcgctttc
     4921 ttttttctcc aactgctgta gagggacacc agtccactcc gatacaactg tagcaacatc
     4981 ttcttctgtt acacgatcag aataaccttg ctcctgtttt gcttcaattg cagaaacttt
     5041 ttgcagcttt ttacgtagtg ctttttcttg tctgcgtaat tgagcagcat tttcaaagtc
     5101 ttgtttttgg atcgctgctt ccttttcttg tactagttca tcgatttcta gtttgatcac
     5161 agttgatttt gttaagtgat cggtttgatc caaacggact ttcgctgctg attcatcgat
     5221 caaatcaatt gctttatcgg gtagttgacg agaagtgata taacgaacag aaagattgac
     5281 tgctgctcgt acagcttcat ctgtgatctc cactccatgg tgctcttcat atcttgtacg
     5341 taatccttga agaatcactt ctgcttcttc aggagttggc tcatctactt gaatgcgagc
     5401 aaaacgtcgc tctaatgcag aatctttttc gatatatttt tgatattcat ctagggtcgt
     5461 tgctccgatc gtttgtaatt ctcctcgagc taacgccggt ttcaagatat tcgaagcatc
     5521 aattgctcct tctgctccac ctgcaccaat taaggtatgc aattcatcaa tgaataagat
     5581 tacttgacca tcattataga tttcgtcgat gacctttttc attcgatctt caaattcacc
     5641 gcgatatttc gtaccagcaa ccaaagatcc catatcaagc atcatcaggc gcttttcttg
     5701 catgtcttct ggcacttcac ctaaaatgat tttttgagct aacccttcag caatggctgt
     5761 tttgcctaca ccaggttcac ccaccagtac agggttattc tttgtccgtc ggctaagaat
     5821 ctggataagc cgtttcactt ctctcgaacg accaacaact gggtccagct tgttttcttt
     5881 tgctaatttc gtcaaatcac gtgctaatga atctagcgta ggtgttcctt gcggtgtttg
     5941 ccgtttatct tgtacattta catttctacg acgattcatt ccttttccag cagaatcacc
     6001 agctagcccc attttttgtt tcagaacttg acgggctttt gaaaggctga tacctaagtt
     6061 gatcatgatt cgagtagcca tgatactttc atcttttaat aagctcatca aaatatgttc
     6121 tgttccaact ttttgagaac cagttttctt cacttcgctg ctagctaaag caaaaacttg
     6181 tttcattctt ggtgaatatg gaagaaagac tcctttaggg taagaacgga taccaccata
     6241 accaatcaga tgttcaattt cttcataaat ttccgtttca ttcaaatcca tttcacgtaa
     6301 tacttttcca gcaattccat tttgctcgac cactaaggct agtaaaacat gttctgaact
     6361 aactgattga tgtttcaacc gttttgcttc ttcttgtgca atttctaata ctgcttgggc
     6421 tctttcagta aaaagttctt ccatctaatc tcacttccca tcttcataac ttaaacgttc
     6481 cagaaatgct cggagaatcc gagcacgtgt atgatcttca tattcattga aattcaatgt
     6541 gttttttgca attgcactca acatcaagtt tccttctttt tttgtaatta tttggtcttc
     6601 ataaagtttt tgaataatag caaaagcatt tttctcactg attgtatcat caaataactg
     6661 atttatctgc tcaagtaatt gttttttatc tgaaatcctt acttttgcaa ttcgtatata
     6721 accaccacca ccacgtttgc tttctactag ataaccacgt tggatggtaa aacgggtatt
     6781 aatcacatag ttgatttgtg aaggaacaca gttaaagagg tctgccattt caatccttcg
     6841 aatctcgatc atttcactat tttccagaat tttctttata tatgattcaa ttaaatccga
     6901 ggtattctga tgtgccatct tattcattcc ctttgactaa tattgacctt aattataacg
     6961 aatttgataa tagaaagaaa gaagaacgct ttttgttaaa taaatccttt agaatcaaca
     7021 aaaaaaaata cggaatatac tattccgtat cgacgcgccc aagaggagtc gaacccctaa
     7081 ccttttgatc cgtagtcaaa cactctatcc agttgagcta tgggcgcata ttcaatttaa
     7141 aaaaattata aatcatttga aaacaaaaag caagataaaa aaaatcggga agacaggatt
     7201 cgaacctgcg accccttggt cccaaaccaa gtgctctacc aagctgagct acttcccgtt
     7261 taaaaaataa aaaagac
//
LOCUS       DAZULR010000090         7121 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.095, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000090 DAZULR010000000
VERSION     DAZULR010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7121)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7121)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7121
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.095"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(8..3157)
                     /locus_tag="ACG8ZV_002620"
     CDS             complement(8..3157)
                     /locus_tag="ACG8ZV_002620"
                     /EC_number="3.1.21.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009035 - type I site-specific
                     deoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HsdR family type I site-specific
                     deoxyribonuclease"
                     /protein_id="HFS4997879.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWSNLRQ
                     KIISNNQAELNDSPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIERENPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIIQIELK
                     QVTAKDGFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKTLMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGVSSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMESVKKESYLDPTVFEAEEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKESDWLIKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSAQQEEMQKIIEEYNQYYDTAWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVQSSTLNNQIQLLEE
                     QIGVYETVKGSLMEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDNLIHA
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKAKHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
     gene            complement(3171..4388)
                     /locus_tag="ACG8ZV_002621"
     CDS             complement(3171..4388)
                     /locus_tag="ACG8ZV_002621"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HFS4997880.1"
                     /translation="MSNDTRPEIRFPGFTEDWEERKLGDMMDVTSVKRIHQSDWTNSG
                     IRFLRARDIVSAAKNEEPSDYLYISEEKYNEYSKNSGKVSQGDLLVTGVGSIGVPLLI
                     TDDNPIYFKDGNIIWFKNEHKIDGNFFYYSFINNKIQKYIRDVAGIGTVGTYTIDSGK
                     KTPISLPTYDEQIKIGSFFKQLDHTIMLHQHELDLLKETKKGFLQKMFPKNGAKVPEV
                     RFPGFTGDWEERKLGEVVVFLNGRAFKQQELLDSGKYRVLRVGNFNTNDRWYYSNLEL
                     EEDKYANKGDLLYLWATSFGPEMWNEERVIYHYHIWKLKFLSKELDKQYLYTWLLTDK
                     EKIKESTNGTTMVHVTKGGIEQRTFQFPPDINEQQKIGAFFKQLDDTIALHQRKLDLL
                     KETKKGFLQKMFV"
     gene            complement(4378..5973)
                     /locus_tag="ACG8ZV_002622"
     CDS             complement(4378..5973)
                     /locus_tag="ACG8ZV_002622"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity
                     [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HFS4997881.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYSISPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVEVLGHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLATFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEAWLQGALEVFKHEQ"
     gene            6098..6883
                     /locus_tag="ACG8ZV_002623"
     CDS             6098..6883
                     /locus_tag="ACG8ZV_002623"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0009036 - type II site-specific
                     deoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SinI family restriction endonuclease"
                     /protein_id="HFS4997882.1"
                     /translation="MPNKNRTFESILNEGLTTEPASIIFDEVIDDVEDSKYHKNLKEL
                     FYFALNNGPSLFTGISVPDSDNPLIMAKIYLTKWCNKYIRDRNNPALKKPLKTFGEKD
                     AALTTRVAANANIDDQKVLNDYLRGHFLYMSAENMNGSILEEYLAEVLEPEGWIWCAG
                     SVYRAVDFCYLGTSPILLQVKNKYNTESSSSSAIRVGTTIRKWNRLNKSTKISGLDSP
                     IPNWKALIEMTEASKELAAKLTENSYLAYINEKSTRELWTLDD"
     gene            6876..7118
                     /locus_tag="ACG8ZV_002624"
     CDS             6876..7118
                     /locus_tag="ACG8ZV_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997883.1"
                     /translation="MTNNILISIYPRYMEKIINKQKNFEFRNFYLTSDPYNIFWIYET
                     IPTKALKYKLIVKNPITKLKKNQHYFLGDDEFEQLV"
BASE COUNT         2072 a         1446 c         1181 g         2422 t
ORIGIN      
        1 ttctcgttta cctcaattca ttttcaagtg gaatcaactc atcatctaac attttacgcc
       61 atgctcgctt catttcttgt gggtatttaa atggtttcgc ttctggatgt ttggctttat
      121 atccttcgta atccttactg ttgataattg ctttcatatt aggaattgga tcttcacctg
      181 gcatatattg cagattagaa gcatgtaatt ctttctcaga aacaaaccac tcattggaaa
      241 aggcatgaat caaattatca cttgcttgtg taaaatagcg acgtttaatg acaaagatat
      301 cttcattact atctaaagtc cccacatcaa atgcatttaa aatttgtcgg taaacttctt
      361 tgactccttc tgttttattc aatttagcca aagctttttc aatttcttct cgtgcatctg
      421 aactattcgc agcataagtt cctagtaatt gatcaatata agtagaatca atatcataca
      481 acttagtggt attttcacta taaaattcga tcgttgaaaa atcttctccc tctttttctg
      541 gttcttcctc catcaatgaa cccttcacgg tctcgtacac gccaatttgt tcttccaaaa
      601 gttgaatttg attgttcaaa gttgaagatt gcaccatgtc atcattgtaa tcatcataag
      661 tcactaacga ttcatacgca cgattcaatt cttgaaatgc tttgacgtac tcgatacgga
      721 tttcaagtgg cgtatgttca tcaatggatt ccatggatga aacctctttt aacttaccat
      781 atgcttgctt gaatcttttt ttggattctt ggtaacttgg ataaatcaaa cccgattctt
      841 ctttagcttc tgaatacagt tttgtcgcat cctcgacatt cttctccatt gtcgctggct
      901 ttcggaaagt aacaattagt ccttttgttt tttcaggata cgtacggttc gtacgtgaaa
      961 aggcttggat caatcctgca tactctagat tacgatccac aaatagggtt tgaatcgtag
     1021 gggcgtcaaa acctgtcaat agacgatcca ctacgattac taaatcgatt tgtttcccaa
     1081 attgtttgaa ttccgctctt tttcgtgcca aacgattatt gatgtctccg ttataacgct
     1141 caatgtctgc tagtgaccag gcagtatcat aatactgatt atattcctca ataatttttt
     1201 gcatttcttc ttgttgggca cttgaatctc ggctattttc ttctaatgaa taggtaatag
     1261 cgattcgtgg gaaatcagga tcctccatcg ttcgtccttc acggataggc tgattgggaa
     1321 actcttttat taaccaatca gattctttcg tcatctcttt gatggcccga taatactttt
     1381 tggccatatc aatggaactc gtggttaaga tcgcagactt cgttggacgg ccatttcgaa
     1441 aatcaaattt tgtataggca ttgtctggac ggaacatttt atgaatgact ttttggatat
     1501 gttcctctgc ttcaaaaaca gtagggtcca aataactttc ttttttgaca gactccattt
     1561 gatcgatcat acgattgatc tgttccggtg aatactctgc atatgtttct acttctttta
     1621 atttccgata gattttattc tctaatgaag tcggctccac ggtgttttca tgctctactt
     1681 gaaatcctaa aaccgagcca tcttctaatg cattcttgat ggtataggtg tgcaagacct
     1741 ctccatactg atcatgggtc gtacgtgcca attgcccttt ggcttgtttc cgattctcag
     1801 ggaaaatcgg tgtacctgta aagccaaacc aagtggattt cggaaacatt tttttgattt
     1861 cttccatatt ttcagcactt aacgctcgat gacactcatc aactacaaac acgatatgtt
     1921 gccccattaa tttttggaag cgattggttc cttttttctc ttcctgtttc tttgcatatt
     1981 tcaacgccgc atctagtttt tgacgggttg taatgatcac aacattcgca ttggcatctg
     2041 ccaacagagt ttcacttaac tctttggcac ttcctgttcc cacgatcaag ctattcgctt
     2101 tggcattacc agaagaaacc ccagtattaa actccgaagc aaatttcgta aactctgtgg
     2161 tggtctgatt atctaaatct ttgcggtcca ctaacatgat cgttcgatcg atccccgatt
     2221 ttcgtgctaa aagcttagta gatacaaaac tagtcaacgt ctttcctgaa ccagtcgcat
     2281 gccacacata ccctgattga tgtttatttg cggcaataaa caaggcttga atcgcatgca
     2341 cttgataagg atgtaacacc atgagggttt tattgtcttg atcttcactg acaatcgtat
     2401 aatccgcaat caagcgatgg gcatctggga tatttagcac ttgtttgcaa aactcatata
     2461 agttttctac ctttttatta tctttcgttc gccaactaaa taaaaactta ggatgcaaat
     2521 ccttcggtaa ggcatttgca aaataccgag tcgtttgttc attggaaacc acaaacaact
     2581 gtaaggtcga aaagatattg ttccgaaaca tgccttcttc agcatatttt ttgatttgat
     2641 taaacgcctg ataaaaacca tcttttgcag ttacttgttt tagctcgatt tggataatcg
     2701 gtaagccatt gatcaataag gtgacgtcaa aacgtcgatc ccgcgcttct atgttacttc
     2761 cacgttttgc aatttgatgg accacttcat aagtagagat tcctccacca atgtcttgat
     2821 tggaataaag gataagtgag acagaaccca attgcggatt ttcccgttca atcgtgatcc
     2881 gagccatccc attttcacct tttaaccatt tcgcagcatc aaatggggtt ttcgtccgta
     2941 gcaataattc ggttttgatc gtttcaaact ctttatcggt caaaggagaa tcattcagtt
     3001 ctgcttgatt atttgagatg attttttgac gtaaattgct ccaaagatct tcttctgatt
     3061 ttagatccgg acgatacgtc cactgattat gtccttcccc gaggacacga atcaactgtt
     3121 cttcgacttc cgcttcctca cggtgactaa ttttcattct tcttccctcc ctaaacaaac
     3181 atcttttgca agaagccttt tttcgtttcc ttcagcaaat ctaacttacg ttgatgaaga
     3241 gcgatcgtat catctagctg cttgaagaag gcaccaattt tttgttgttc atttatatcc
     3301 ggtggaaact gaaatgtcct ttgttctata ccacctttag tcacatgtac cattgtcgtt
     3361 ccgttagttg attctttaat tttctcttta tcagtcaata gccaagtata tagatactgt
     3421 ttgtccaatt ccttagataa aaatttaagt ttccaaatat gataatggta gattacacgt
     3481 tcttcattcc acatttcagg accgaagctt gttgcccata aatataagag atctccttta
     3541 ttagcatact tgtcttcctc taattctaag tttgaataat accatctatc attagtatta
     3601 aaattaccta ctcttaaaac cctatatttt ccagaatcaa gtaattcttg ttgtttaaaa
     3661 gctctaccat tcaaaaaaac taccacttcc cccaacttcc gctcttccca atctcccgta
     3721 aatcctggaa aacgaacttc tggcactttt gctccgtttt tagggaacat tttttgtaag
     3781 aatccttttt tcgtttcctt cagcaaatct aattcgtgct ggtgaagcat gatggtgtga
     3841 tcaagttgtt tgaaaaatga accgatcttg atctgttcgt cataagttgg aagtgagata
     3901 ggtgtctttt taccactatc aattgtatag gttccgacgg ttccaatgcc tgcaacgtca
     3961 cggatatact tctgaatttt gttatttatg aacgagtagt aaaagaagtt tccgtcaatt
     4021 ttatgctcat tcttgaacca aatgatgttt ccatccttaa agtaaattgg gttatcatca
     4081 gtgattaata aggggacacc tattgatccg acaccagtta caagcaagtc tccttgagaa
     4141 actttacctg aatttttcga atattcatta tatttttctt ctgaaatgta aagataatcg
     4201 gatggttcct cattttttgc agctgagaca atatcacgag cacgtaaaaa tctaatacct
     4261 gagttagtcc aatctgattg atgaattcgc ttcacagaag taacatccat catatctcct
     4321 aacttacgct cttcccaatc ttccgtaaaa ccaggaaacc ggatttctgg tcgtgtatca
     4381 ttgctcatgt ttgaacacct ccagcgcacc ttgtaaccac gcttcatttt caggtgttgt
     4441 ttgcagggaa gagatagctt ctaaaagttc tttttctagc acttgctgtt cttgtcgtat
     4501 cttcttgatg tcatttccga catgaaccat atcaattggt tcttcttctt cgaaagtatc
     4561 gacatagcgt gggatattta agttatagtc attttctttg atttcatcaa aggttgccaa
     4621 atgagcgtat ttctcgacat cttttctttc agcgtaggtt tcgaggattt tttgaatgtt
     4681 ttcttccgat aatttattct gatttttccc tttaacaaat tcacgactag catcaatgaa
     4741 taatacatct cgagtttgac gattcttctt caatacaatc accgtcgttg gaatcgatgt
     4801 accaaagaac aagttcgcag gcataccgat cacagcataa atactgccgt cttctaataa
     4861 tttttgacga atgacccctt ctgcagcacc acggaataaa accccgtgtg gcaagacgat
     4921 agccatagtc cctgtttcct tcaaatgata gaaaccatga agaagaaacg caaaatctgc
     4981 tttggatttt ggcgctaatt tcccgtagcg attaaaccga gaatcatcta agaaggtcgt
     5041 atctgctgac caattagccg aataaggtgg attcatcact actgcatcaa atgtgtaagg
     5101 ttcatctgtt ggccagtcct tattcaacgt atccccattg cggagattca tttcttcggc
     5161 atctacccca tgtaaaatca agttcatttt tgctagattg tatgtcgttg tatttagttc
     5221 ttgcccatga tatttaacgt tatctggatg agttaagtag ttacgtacat ttaacatcaa
     5281 ggaacctgaa cccatggttg ggtcaaagac actaaagaat cgtcgttctt tttgatccaa
     5341 cgtcacgatt tgtgccatca tatcagaaac catatgaggc gtgtaaaatt ctccggcttt
     5401 cttccctgct tctgaagcaa attgactgat cagaaattca tacgcatccc cgatcacatc
     5461 cccatcgtga cctaaaactt ccacgtcatt caatttcttg ataacttcgg taatcgtcac
     5521 atttcgttgt tgctcatctg ttcctagttt ttttgattgg agatccacat catcaaataa
     5581 cccattaaat tgattgtagg tagatgccaa ttgcacaaag gctttgttta gatcgttcaa
     5641 ttggaacgtt gcttgttttg cttgatccgc taagacgttg aaaagatact ctggtgagat
     5701 cgaatacccc aaaatatcaa cgattgtggc aatcaggtct tcttttgatt cttcatctga
     5761 aagtaattca cgatacaaca ttgtttgttt gcttactgtg tcatattcct ctaaggattc
     5821 atctgctaaa agaaccactt gttccaacaa acggtcggat aaatatttat agaaaatcag
     5881 tcccaataaa taatttttat attctgacgc atccatttta ctacggagat tatctgccgc
     5941 actaaataat ttttgattta attctgcacc caaaaagata cactcctatc tcttatttaa
     6001 agttgctata taccctctta ttttagcata ctccctttta gaaaaagcaa aaaaaaaaga
     6061 aaaaatctta ttcttgataa caagctacgt gacgtatatg cctaacaaaa atagaacttt
     6121 tgaatcaatc ttaaatgaag gtttaaccac agaaccggca tccattattt ttgatgaagt
     6181 tatcgatgac gttgaagata gtaagtatca taaaaattta aaagaacttt tttattttgc
     6241 actcaacaat ggaccaagtt tgttcactgg tatatcagta cctgatagtg ataatccatt
     6301 aattatggca aaaatttact taacaaaatg gtgtaataaa tacatcaggg ataggaataa
     6361 cccagcatta aaaaaacctc ttaaaacatt tggcgaaaaa gatgctgctt taactactag
     6421 agtagcagca aatgctaata ttgatgatca aaaagtattg aatgactact tgcgtggaca
     6481 ttttttatat atgagcgctg agaacatgaa cggaagtatt ttagaggaat atttagccga
     6541 agtgttagaa cctgaaggtt ggatttggtg cgccggctct gtatatcgag ctgttgattt
     6601 ctgttattta ggaacctcac caattctttt acaagtgaaa aataaataca atacagaaag
     6661 cagttcgagt tcagctataa gagtaggaac aacaattaga aaatggaatc gtttaaataa
     6721 gtcgacaaaa atttctggtt tggatagccc tatccccaat tggaaagcat taatagaaat
     6781 gactgaagct agtaaggaac tggcagctaa gttaactgaa aatagttatt tagcttatat
     6841 taatgaaaaa tccacacgag aattatggac actcgatgac taacaatatc cttattagta
     6901 tctatccacg atacatggaa aaaattataa acaaacaaaa aaactttgaa tttagaaatt
     6961 tctatcttac ctcagatcct tataatatct tttggattta cgaaacaatc cccaccaaag
     7021 ctttaaagta taaattgatt gtaaaaaatc caattactaa acttaagaaa aatcaacact
     7081 actttttagg agacgatgag tttgaacaat tagtttaaaa g
//
LOCUS       DAZULR010000091         7028 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.096, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000091 DAZULR010000000
VERSION     DAZULR010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7028)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7028)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7028
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.096"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..353
                     /locus_tag="ACG8ZV_002625"
     CDS             <1..353
                     /locus_tag="ACG8ZV_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997884.1"
                     /translation="ETRVPKKHYKERLSVAVEEMIESGVEMNLIATYYRTLEELKKQN
                     AKWFFQALLCLEVGVKPSTIKPSEYQALELTYGKFVETKKAKTVSSEWLDYFENINKY
                     GAYYTMKKEDNENE"
     gene            346..1053
                     /locus_tag="ACG8ZV_002626"
     CDS             346..1053
                     /locus_tag="ACG8ZV_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997885.1"
                     /translation="MNKVIYQLTTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSNNYLDVYKHRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSCTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATIDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKRQ"
     gene            1217..1417
                     /locus_tag="ACG8ZV_002627"
     CDS             1217..1417
                     /locus_tag="ACG8ZV_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997886.1"
                     /translation="MNKIIPLLFVLCIGEILMRHGAAVHLNFVVFLGILVFCLIFWRF
                     VLALVSLLFKLIAAIFFIGLFR"
     gene            1433..1612
                     /locus_tag="ACG8ZV_002628"
     CDS             1433..1612
                     /locus_tag="ACG8ZV_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997887.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDIPALKK"
     gene            1937..2200
                     /locus_tag="ACG8ZV_002629"
     CDS             1937..2200
                     /locus_tag="ACG8ZV_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HFS4997888.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            2194..2544
                     /locus_tag="ACG8ZV_002630"
     CDS             2194..2544
                     /locus_tag="ACG8ZV_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFS4997889.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(2568..3182)
                     /locus_tag="ACG8ZV_002631"
     CDS             complement(2568..3182)
                     /locus_tag="ACG8ZV_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFS4997890.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            3496..3918
                     /locus_tag="ACG8ZV_002632"
     CDS             3496..3918
                     /locus_tag="ACG8ZV_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997891.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            3928..4131
                     /locus_tag="ACG8ZV_002633"
     CDS             3928..4131
                     /locus_tag="ACG8ZV_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997892.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            4342..4926
                     /locus_tag="ACG8ZV_002634"
     CDS             4342..4926
                     /locus_tag="ACG8ZV_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFS4997893.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
     gene            5297..6622
                     /locus_tag="ACG8ZV_002635"
     CDS             5297..6622
                     /locus_tag="ACG8ZV_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HFS4997894.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRS
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTKSLNLFTTEETRSQRRKKLAQMIQERIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFIAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGILSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLNIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQINEEN
                     LDKIIDKIRQKYGFTSIVHASSMLESARSITRSTLVGGHAGGNGGIKND"
     gene            6615..6965
                     /locus_tag="ACG8ZV_002636"
     CDS             6615..6965
                     /locus_tag="ACG8ZV_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997895.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIVGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
BASE COUNT         2490 a         1051 c         1358 g         2129 t
ORIGIN      
        1 atgagacacg tgttccaaaa aaacattata aggaaagatt gtcggtagct gtggaagaaa
       61 tgattgaatc aggtgtcgaa atgaatctca ttgcgacgta ctatcgaaca ctggaagaac
      121 tgaaaaaaca aaatgcaaaa tggtttttcc aagccttact atgcttggaa gtaggtgtca
      181 aaccaagcac tattaaacct tctgaatatc aagctttaga actaacgtat gggaaatttg
      241 tcgaaacgaa aaaagccaag actgtttcaa gtgaatggtt agattatttt gaaaatatca
      301 ataagtatgg cgcctattac accatgaaaa aggaggacaa cgaaaatgaa taaggtgatt
      361 tatcaactaa caacggaaga tgtgtcacac tttttaacaa acaaagaaca tttgaatgaa
      421 gtaatcagac ggattcaaaa agactttagt tgtatggaag aaatgaagta ctttattcaa
      481 agagtcgaag aacaattgta tttggaaagt gaaacgagtc aaacgaaggt cacagtcagc
      541 aataattatt tagacgtgta taaacatcgt cctgaaacgg taaaaaaagg aacggagctt
      601 ctacgactag aaacagaaaa atacatcatg aatgtttacc tagaaaggag tgaactggtc
      661 gaaaactttg tcagctgcac gatttgcagg aaacactatt actcagaatc agaatattat
      721 tcaatttttg agagcatgga attaatggaa gaagaaatgg aagagctaaa cagcaaaaat
      781 gcgacgatag acgattatta tcttgtattt actagatttt tgacgtgtgg aacggaatct
      841 atcgtgttaa tgggaatgga ttatgaactc gctgtacccg aagcattttt gagggaatat
      901 gtagaagaag tagataaccc aggcgacgac tggtacacga ctttaactga ttttttagat
      961 acctacactt acgacgatac agaagaaatc caaaatgaac ttgaccgtaa acgaatgcca
     1021 tatcaacgat ttgaaaggaa aaaaaggcaa taatcattta taccgaaaag tgagaatgtg
     1081 tgaaataaga acaaaaacct tgaaattaag ggaatggttc ttatttcgca ccaatcgctc
     1141 caaccgcccc cgccgcttag gtggtgcgaa ataagcgggc aaagcccgat aacctaagag
     1201 aaagaaggag atccatatga ataaaatcat tcctctgttg ttcgtactgt gtattggcga
     1261 gatacttatg cgtcatggtg cagctgtaca tttaaacttc gtagtattct taggaatact
     1321 agtattttgt ttgatttttt ggcgctttgt gttagccctt gtgagtctac tattcaagtt
     1381 gattgcagcc atatttttca tagggttatt tcgatgaaag gagagagtac taatgccaat
     1441 tgcaatagga aataaacggt tacccgtgac attagatgaa aagagacaaa aagaattgca
     1501 gcaactaaag cagaagtacg gaaaaagtga atctaagatt atgtgtattg cgttagatct
     1561 attgatcgcg caagaaaaag caggatttga tataccagca ctaaaaaagt gacgtcactt
     1621 ttcatttgaa gaaacaaaag tgatagcact taattgttcc tactatttag aatattttct
     1681 atgtcctttt tattccattt tgtatcaata actatgaaat ctttaaagta tccagatcaa
     1741 tttttttctt acctgattct aaagattttg ttttcttaaa catattatga tttcctttcg
     1801 actattttca tataaatgtt aacatagttt atggattcat ggaatgttaa tctaatttaa
     1861 tagaaaagga taattaagta tatacgtttt ttcttatgta tgttatacta tgtatataca
     1921 gaaagaggtg tctactatgg aaatgttacc tataaaaaaa tggggaaata gtaatggcct
     1981 tagattgcca aagtatatta tggaatatct tggaattcat acagaagaca aagtgaagat
     2041 aatacaagaa gaagtaaacg gtcagaagcg gctaattatc gaagcggcta atatagaaaa
     2101 tgaattaaca attgaacagt tatttgaaaa ttacactgat gaaagaaatc atgtgacgat
     2161 tcaaaattta ggtgaagcag taggtaatga aaaatggtga gaaaacctag acaaggcgat
     2221 attctattat tgaatacagc acctcgatct ggacacgaac agacaggtaa aagaccttat
     2281 attgttttaa gtcatgatat tattgcggat tatagtaacg ttgttacagt tgctccaatt
     2341 tctagtacaa ctagaaacta tccgctatat gtaaatataa actcagaata tgaaatgaag
     2401 acaacaggaa aagtattatt agatcaacta acgacaattg attatgaagc cagagagtgt
     2461 atttttttgg aaaaagcgca tgatagttta gttgaggagt tattgatgaa agttagaaca
     2521 gtttttcaaa aagtaagcaa ataaaataga aacagcagca tgatcaacta ttcgtgattg
     2581 accatgctgt ctttttttat tctatatacg gtttgtctcg taacattgta gtcttttgca
     2641 atcttagcga tcgcaacacc tttttttaga tcctcaacga tgtttttata aacaagacga
     2701 cgttggggat cttttgcatt ggcactgtat agcttaggac gtcctttata aacaccgttc
     2761 gcttttgcaa tcttaatgcc ttgtgcctga cgtcgtttag attcggtacg ttcttgttca
     2821 gcgatcatgg ccaaaatttg aatgatcaaa tctttaatga atttatccag gagaggattg
     2881 ccaattgctt cggccatgat cggtagactt gtgatgatca gctgcacatt tttcttcttc
     2941 aagtaattga ctgaagcgat gatctcgtcg taatttcttc caagtcgatc aatagcttcc
     3001 acaataaaaa tatcttgatc tcggacgaaa tccagtgctt cttgaaaaac aggtcgatga
     3061 gtaatcgttg cgccagattg tttctcaatg aaaattctct ctgcaccgaa ttttttcatt
     3121 tcttcaatct gccgttgttc attttgatcg atggatgaga cacgtatgta tgcaactctc
     3181 aaaattttta cctactttct gcaactattt aaaaaacacc ctaatcatac acgagaaaac
     3241 cagatttttc aatgtcgcgg tcgtgtctag ttagggtata ccttatatag acaaaaacta
     3301 atgatggagg aaatagtatg tgtcactttt ctttttaaat ggcaatattt tttgtaaata
     3361 aatgtcaatc aagaaaattt aaacgattat gacattaaaa atatatttta tgaattttct
     3421 agtatataac ttgatttatc tgttaagatt tattaagaaa acgttttctt atttttgatt
     3481 tcgaggtgat agacaatgaa aaataagttt attttatctt taggtatttt aactattgga
     3541 attagtgtaa ctggaactac aattcctaca tttgctgata gtacaaatga accaactact
     3601 gtagtagata ataaccaaga attaactcct ttagatagga acggaatagc cattggtaac
     3661 ccaactaacg acttaactgt tactgaaaat tatttaatag tttctccatt acttgctcga
     3721 gcagcttcta aaacgatacg agtgacagga acgatgattt ttgataaagt tggttggcct
     3781 tctagacctc ctcaatcacg gaattggaaa gaaaaaagaa atggttattg gtactatgga
     3841 aaattgtatt tacaaagtta taaatcagct ggaaacaatt ggattgcgac ttattcagga
     3901 accttaacta gaaagtaggg attttttatg ccagaatttg tgaacacacc aaatttttat
     3961 caagatagcg atattctaag taaaattaat ttaccgaaag aagaatcagc tttacaagtt
     4021 cagcgaactt tacaggagac acaaaaaatt caaaaatcaa tttctaatct agaagattct
     4081 gaagaaaaaa gaaaaaaaag agaccaaaaa acatatcaaa aagaaaaata atgattttaa
     4141 aaaaagagtg tctagtcgac attctttttt tctaattgaa agtgttcata aaatcaccca
     4201 tttctggaca cttccttttt ttgctttatt tttcaaaaaa acaattcatt tcatgttcat
     4261 aaacccataa caatatctat gttcagttaa actatatgga taaagttatg ttacaataaa
     4321 attaatgaag gagtgatttt tttgaaaata ggatacgccc gggtatctac tggtttacaa
     4381 aatttggatt tacaagaaga cagcctaaat aaatttggtt gtgaaaaaat ttttactgat
     4441 catatgagtg gggcaaaaag taatcgacca ggattagaaa tggccattga ttttgttcgc
     4501 tctggcgata cacttgtcgt ttggcgctta gatcgtttag gtagaaatat ggaagatttg
     4561 atttcaatcg tcaatcgact gaatgagcgt ggtgtgagtt ttcatagtat tcaagaaaat
     4621 attacgatgg acaaatcaag ttctacagga cagctcatgt ttcatttgtt tgcggcattt
     4681 gcagaatttg agcgtaattt gatcctggaa cgatccgcag caggacgagc agctgctcgt
     4741 gcaagaggac ggtttggtgg tcgtcctgaa aaattgtctg aacaagattt ggaattactg
     4801 aagactttag tggatagcgg tacacctatt aagactattg cggaacggtg gaacgtctca
     4861 agaaccacca tttatcgtta tttggcaaaa atggaggaga aaaatggaaa gacaaattct
     4921 cattagtttt tgtcatttaa tgctgaaaat ttttgccatt tatctagaaa agtgacaata
     4981 gtatgagaat tttttgtaag tgtctactga taacttatta tcaaatgttg taaggatttt
     5041 attcatttgt taatattaaa gaacggaact ccaaaaaagt ccgtactcta atttgcagtc
     5101 tctcactctt ttagagtgag agtttttatt agattttcaa attaattagt aaagtgatag
     5161 aataaattga tcatacaaat cataagaaga agcagggtga tagcatacct atgcttcttt
     5221 ttttatgtat ttagctattt cttctttaca acatcgaaca tatgtttgta taatgtggaa
     5281 gaatggagtg ttatttatga tggattattc aaaagagcca gtaaatgatt actttttaat
     5341 cgatatgaaa agcttttacg caagtgtcga atgtatagaa agaaatttag atccattaac
     5401 aacagaactt gttgttatga gtcgatctga taatactggt tcaggattga tattagcttc
     5461 ttctcctgaa gcaaaaaagc ggtatggtat tacaaatgtg agtagaccac gtgacttacc
     5521 acaaccattt cctaaaacac tacacgttgt tccaccacgt atgaacctat atatcaagcg
     5581 aaatatgcag gtaaataata ttttcagaag atatgtggct gatgaagatc tactgattta
     5641 ctcgatcgat gaatcgattt taaaagtgac aaaatcactg aatcttttta cgactgaaga
     5701 aacacgaagt cagcgaagga agaagctcgc tcaaatgatc caagaacgta ttaaagaaga
     5761 gttaggtttg attgctacgg taggcgtcgg cgataatccc cttttggcta aattagcctt
     5821 agacaatgaa gcaaagcata atgaaggatt tattgcggaa tggacgtacg aaaacgttcc
     5881 tgagaaagta tggaatattc ccgaaatgac ggacttttgg ggaattggtt ctcgaatgaa
     5941 aaaaaggctc aaccaaatgg gaattttgag cattagagac cttgctaact ggaatcctta
     6001 tacgattaag aatagattag gtgtgattgg attacagctg tacttccatg ctaacggaat
     6061 cgatcgaaca gatatagcaa tcccgccaga accgacaaag gaaaaatctt atggtaattc
     6121 acaagtgtta ccacgagatt atactagaag aaatgaaatc gagctggtgg taaaagaaat
     6181 ggcggaacaa gtagccattc gtatcaggca gcataattgt aaaacaggat gtgttcattt
     6241 aaacattggt acgtcgatct tagaaacgag accaggattt tcacaccaga tgaaaatacc
     6301 tatcacagat aatacaaagg aattgcagaa ttattgtctt ttcttgtttg ataagtatta
     6361 tgaaggacaa gaagtaaggc acgttggaat aacctatagc aagcttgtgt acaccgattc
     6421 gcttcagctg gatttattta gtgatccaca aaagcaaatt aacgaagaaa atttagataa
     6481 aattattgac aagattcggc aaaaatatgg ttttacgtcg attgtacatg cttcttcaat
     6541 gttagaaagc gctagaagca ttactagaag cacacttgtt ggtggtcatg cgggcggaaa
     6601 tgggggaatt aaaaatgatt gattacaatg atcgtggacg tttaaagtgg gcagggtttt
     6661 atttatctga tcatactgaa gaaattgatg ccgacaatga acaacgaacc agtcaaaatt
     6721 tagcaaaaga acaaatgacg actgaagaga ttgcggaagt attgaacgct gcagtcataa
     6781 aaaatagatc agtatctatt caaaaagaag aacgaaacgc tgaaggatac tatccagaag
     6841 atattgttgg caagatctta ggtagtgatg agctggggat ctacgttgga aaagacaaaa
     6901 ttcactacga cgaaatacgt catatcgaat tttaccagga taataaatgg agtcgattag
     6961 aatgaacggt tctgttgcaa agttttaaat aaagaataaa atcccttacg gtatctatga
     7021 tttaagct
//
LOCUS       DAZULR010000092         6644 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.097, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000092 DAZULR010000000
VERSION     DAZULR010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6644
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.097"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(1..859)
                     /locus_tag="ACG8ZV_002637"
                     /pseudo
     CDS             complement(1..859)
                     /locus_tag="ACG8ZV_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEfa10 family transposase"
     gene            1102..1557
                     /gene="tnpA"
                     /locus_tag="ACG8ZV_002638"
     CDS             1102..1557
                     /gene="tnpA"
                     /locus_tag="ACG8ZV_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HFS4997896.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            1822..1920
                     /locus_tag="ACG8ZV_002639"
                     /pseudo
     CDS             1822..1920
                     /locus_tag="ACG8ZV_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558064.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2143..2373)
                     /locus_tag="ACG8ZV_002640"
     CDS             complement(2143..2373)
                     /locus_tag="ACG8ZV_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HFS4997897.1"
                     /translation="MDEAMDHPLLNKFIKDLILQIFSMIDEQEPTESKRHRAQGIIKI
                     AKRMFSIKGVLSYTVLIQKIPNHLVYKNNVED"
     gene            complement(2603..3421)
                     /locus_tag="ACG8ZV_002641"
     CDS             complement(2603..3421)
                     /locus_tag="ACG8ZV_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFS4997898.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            3582..4271
                     /locus_tag="ACG8ZV_002642"
     CDS             3582..4271
                     /locus_tag="ACG8ZV_002642"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HFS4997899.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            4285..5787
                     /locus_tag="ACG8ZV_002643"
     CDS             4285..5787
                     /locus_tag="ACG8ZV_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFS4997900.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            5800..6276
                     /locus_tag="ACG8ZV_002644"
     CDS             5800..6276
                     /locus_tag="ACG8ZV_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFS4997901.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(6373..6483)
                     /locus_tag="ACG8ZV_002645"
                     /pseudo
     CDS             complement(6373..6483)
                     /locus_tag="ACG8ZV_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2172 a         1032 c         1204 g         2236 t
ORIGIN      
        1 acttgtcctc gataagaatt gtagcgccgt gatttacgtg tgtatgtcgt tacttttatt
       61 cctagcttct tgatcaggcg ctgaactttc tttttattga tagagaaacc gcggtttctt
      121 agttcattgg tcatccgtaa acagccataa tccttgtgct tctcccgaac tttaagcatt
      181 tccgcttcaa tctcttgatc tggattttta cggtccaatc gtttttgcca gtacataaag
      241 attgccttag ggaactttaa agtttctaga agctcaacta atttaaacgg tcctcggagg
      301 cttgcgatga ttcgtgcgat tgcttcattc gtcgttgttg ggcttcctgt tttcgcagct
      361 tcctcaattc ttttaaaaag gcattttcaa tttgaaggga acggactcgt ttctccaact
      421 cctcgatgcg ttcacgttct ttagacgttg ctttagttgt agattttttc ttatttttgg
      481 gttcattttt cttagacaag ataggtggac atcctttcgt ttttgagagt ccatcgatcc
      541 caccctcacg gaattgacgc atccaactag cgatcaaatt agggttgttc atgttaagtg
      601 tgttggcaac ttcacgatag gacagctcac ttgttagata taactctatc gcatccagct
      661 taaattgaac agaatatttt ttcttttgtc gctttcttac tagaccctct tcaccaaatt
      721 cttgataggc attgatccag cgcttcactt gtgatggagc cttaatggaa tatttctttg
      781 ccagataatc acttccgcct ttaccatcca agtaatcatg aacgatcttt aatttaagtt
      841 caaaagtata cttagccata aaaaataccg acctccaaaa gttagatttt ttggtctaac
      901 ttttgggggt cggtacaaaa cttaaaagtt ttagaccctt ttattttctt aatgacttca
      961 gtcagttttg tgcgtaaagc gtgcgaaaca agaaaaccgc gcgtttctac gcgtggaaga
     1021 agtatcttta gcgataaaaa ctcctttcga tatactagtg agtggctacc aaccgctcat
     1081 cagatcgaaa ggagtttttt catgtcaaat gacgataaaa gtttagcata tactcgttgg
     1141 aattgtaagt atcatattat ttttacacca aaatatcaac gaaaagtaat ctatgggcaa
     1201 ttacgaaaag atcttggaaa aatacttagg aagttgtgcg aaatgaaaga tgtggaaatc
     1261 atagaagcac atgcaatgct agatcatatt cacatgcttg ttcgagtacc accaaaaata
     1321 tgtatatcca gttttatggg gtatctgaaa ggtcgtagtg cggtactaat ccacgagcag
     1381 cacgcaaatc tcaaatataa atacggaaac aaatcctttt ggtcgaagag atactatgtg
     1441 agtacagtcg gattgaatca aaagacaaat gaaaaataca tccgtgaaca agaagctgat
     1501 gatcgcattc gatatattat aagtaaaaga gagtacgtag aaccatttaa aaaataaaga
     1561 gaagtaagtg agtgaagatg agcagttggc ggtcttttaa aaatcccctt ttaaggggca
     1621 gcgagtgtcg accccttcta gggggattaa aaatacaccc gtcctcacgg gtgtatgggt
     1681 tactgataga cttgatttta actggtgtca gaaacttatg tccagaaagg gtgatgaaat
     1741 tttggcaatt tacggctatt caagaattag cacaagcaac caagattaca aaacacaaat
     1801 tcaaacatta gaaaatgctg gcgcagaaat aatcttccta gaaaatcact ggattatcga
     1861 acacctttgg aagtattttt gagttacgta agtattgatg atctgtctaa cttaatttga
     1921 caattaagag tatatttact tcagatggta aggcaacaaa ataaaataca ataggcagat
     1981 gaactaataa ataaaatctg tattaaatac agataaatta atataaaaat caaaaggatc
     2041 ataaactttt aacaagtgat gaaatgggtg gaaattgatt cttatagaca gtttgtctca
     2101 taacattgaa gtattttgca attttagcat tgaaacactt ttttaatctt caacgttgtt
     2161 cttataaaca agatgattgg gaatcttttg aattaacact gtatagctta gaacaccctt
     2221 tatagaaaac attcgcttag caatcttaat aattccttgt gcccgatgtc gtttagattc
     2281 agtaggttcc tgctcatcga tcatggaaaa aatttgaagg atcagatcct taataaattt
     2341 atttaagaga ggatgatcca ttgcttcatc catactcgat aaactagtga taatgagcta
     2401 cacgtttttc tttcaagttg atcaatagct tccacgataa aaatatcttt agataaaatc
     2461 aagaaccgta ggaactacag ggatatttgg tcaataagag ccaccgctat tagtaaaaaa
     2521 taagctatca agtatgctct catcccaaga attgcctact tcaatcgtta aaaaccgtta
     2581 ggtttagcta agtgggggta gttcactcaa tacttttatc aataatagag cgcaaaactt
     2641 tttctcttaa ttcaactgaa tcaatattat tgttttgttc ataaccatga actaatagat
     2701 cacaaatata aagttgtgat atttttccag ctaaagatcc accattaaga aattcttcaa
     2761 tggctgtttg taaaactaag tctgcagact ttcctatagg tgaatgaata tagttagtta
     2821 tagcaataat ttttgcgcca ttttttttag ctattttcaa tgaatcataa gtatctttcg
     2881 ttttcccaga taaagaaaaa atgattacta aatcattaac tgttaataaa gaagcgactt
     2941 gggcttgaaa atgagggtct agtacagctt ttgcttgaac tcctacgcga agaaacatat
     3001 tttctaaatc aagactagta tttccactag atcccactcc aaatatatat atgttttttg
     3061 attgagtgat cattttaatg gcttcattca atttttcttc gtctaaaagc ctaatagtgg
     3121 aatagagagc ttctgttaaa ctattagcaa tttcatcata gtactttaca ctagtcggat
     3181 gttctttttt ttgactaaag tcttcctttg caatttcaat ttttaaatca gaaaaaccag
     3241 aaaaaccaat tttttgacaa aagcgaataa tagtagcatc gccaactttt gtgtttttct
     3301 taatatcact catcgtacta taaataatag ttttcccaga atttaaaata aaatcagcga
     3361 cttttttttc agacttcgtt aaaaatggat aattttcttt aattaaatag atataactca
     3421 tacaaactcc tctacaattt caacttttct ccattatact ccaaaataat aaaaaaaact
     3481 cctaaatact ccatttttat ctttactttt atgaaagcgg atgctatatt gtttttggag
     3541 ttgttatcca aaaataataa aaaattggag tgtttaggat aatggataaa aagaggtttt
     3601 tagatcttat ttcaaaaggt ttgattgttt cctgtcaagc attacctggt gaaccatttt
     3661 acaaagagga agaaagttta atgccttatt ttgctttggc tgctcaaagg gctggagcag
     3721 ttggtatacg tgcaaattct gttcgagata ttattgaaat tagaaagtgt gtatcattac
     3781 caatgattgg aattattaaa agagattatc caccagaatc tccattcatt actgccacta
     3841 tgagagaagt agatgaatta gtagaaaccg gtgttgaggt aatcgctctt gattgcactc
     3901 ttagaaatcg acatgatgga ctatctataa attcttttat tactaaaata aaagaaaaat
     3961 atcctcatca gttatttatg gcagatattt ctacatttga agaaggcaaa aatgcatata
     4021 aagcaggaat agattttgta ggaactactt taagtggata tactgaggaa agtaaaaaac
     4081 aagatgggcc agatatagat ttgattaaaa aattggtaga agaagggatt tgtgtaattg
     4141 ctgagggaag gattcatact ccagaacaag caaaagagat aaaaaaaata ggagttgcag
     4201 gtattgttgt gggtggtgct attactcgac cacaggaaat tgcatcaaga tttgttaaag
     4261 cattaagtta gggggagaaa taaaatgttt aaaaaatttt cacaattagg acgcgctttc
     4321 atgttaccaa ttgctatatt accagtagcc ggattactat tgggactggg aggagcgtta
     4381 acaaatgaga gtgctataaa tgcttatcca tttttagatc aaccgtggtt gcatacaatt
     4441 ttaagtatta tgagttatgc tggaaatgca gtttttgcaa acctagcact aatttttgca
     4501 attggtattg ctgtaggact tgcaaatgga gataaaggaa cagctggttt agctggtgga
     4561 gtagcttatc tagtatatac tgcaactatt agtgggtttc ttgaactttt ttcagcaaaa
     4621 gatgcaacac tagatacagg tgtagtggga tcaattgttg ttggtggtac tgttgcattt
     4681 ttacacaatc gttatagaaa aattgaatta ccacaattct taggtttttt tggaggatca
     4741 agatttattc cgattgtttc tagtttagct gcaatcatta ttggttcttt cttttattta
     4801 atttggccac caattcaaaa tggtttagta gttgctggtg aacaaattgc ccaaatgggt
     4861 agtttaggaa cttttttata tggtttttta ttgcgtttaa caggtgctgt tggactacac
     4921 cacaccattt accctttgtt ctggtataca tctttaggtg gtaccgaaac tgtagctgga
     4981 tcaacaattg ctggagccca aaatattttc tttgcccaac tagctgatcc aaaccacact
     5041 ggtctgttta cttatggtac tagatttttt gcaggaagat ttgcaacaat gatgtttgga
     5101 ttaccagcag catgttatgc aatgtatcgt gcaattccta agaaaaatcg taaaaagaat
     5161 ggtgggcttt attttagcgg ggcccttaca tcatttttaa ctggaattac tgaaccagtt
     5221 gaatatatgt ttttatttgt tgctccttgg ctttatgtga ttcatgcatt cttagatgga
     5281 ttatcttttt attttgctga tatcttaaat attcgtgtag ggaattcctt ttcaggtggt
     5341 ttgatcgact ttttattatt cggtgtactt caagggaatg acaaaactaa ttggttaaaa
     5401 ttaattcctt ttggtattgc atgggcattt atatatttct ttgtttttac attctttatc
     5461 aaaaaattta aggtagctat tcctggaatg gaagaagaat cagaagttca ttctgaaaaa
     5521 gtaataaaca aaaatacatc attacatgaa gagtctctta tcattattga agctcttggt
     5581 ggaaaagaaa atattgagtc tgttgaagct tgtgcaactc gtttgcgtgt tgctgttacg
     5641 aatggggaga ttattcaaaa acaaacaata aaagacactg gtgcaactgc tgtcttcgaa
     5701 gtgaagggtg gcatccaagc tgtttttgga gggaaagctg acttattaag tcaagaaatc
     5761 aatcaaatat taggaaaaga taattaggag gtttttaata tgtttgaaat tttcaaaaag
     5821 aaaaaacaag aaacttttta tgcaccttgt tccggaaaaa tcatttccat cacagaagta
     5881 aatgatcctg tcttttcaca aaaattacta ggtgatggtt ttgccgtcat acctgatggt
     5941 tcaaaaattt atgctccatt ggctggtcga gtaacaaata tatttcctac taaacatgct
     6001 attaatataa aaagcaactc aggcattgat tatttgattc atattggaat tgatacagtt
     6061 gaattacaag gagagccttt ttcgatttgt gttcaagaaa atgatgaggt tactcctgaa
     6121 acctcgttgg ttgatgtgga ttttgacaaa ataataaaat ctggtaaaga tacttctgtt
     6181 atagttgttt ttccggagaa aaatcagttc aatgatttaa taatagataa tggtcgaatt
     6241 gctcatggga attcatgtgg aaaaatcact ttttaaaaaa gtgtatataa aaagctataa
     6301 aataagctaa ataggatatt tgtcaaatga agttggtgaa cagaaagaac tgttttcttt
     6361 ctgttcattt ttttatttta ttagtaatga ttccccatgc caaatcatga tccgtaattt
     6421 aaagttataa aagcttcgaa atccattggc atttcgttgg aataccttga tatgattatt
     6481 caaatataaa atatagagag aagagagaga gggaagatat ttataaaggg caaagttatg
     6541 tttactcaac ttaggaaata gaaatagatc aatttatatt ctcttgtcaa tcgaatatga
     6601 accttagcac tatataccaa atatagtaaa atgctgaaag atgt
//
LOCUS       DAZULR010000093         6500 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.098, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000093 DAZULR010000000
VERSION     DAZULR010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6500
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.098"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(1..1099)
                     /locus_tag="ACG8ZV_002646"
                     /pseudo
     CDS             complement(1..1099)
                     /locus_tag="ACG8ZV_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element ISEfa7 family transposase"
     gene            1307..2281
                     /locus_tag="ACG8ZV_002647"
     CDS             1307..2281
                     /locus_tag="ACG8ZV_002647"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFS4997902.1"
                     /translation="MRQLHKEQIETAMAALKEKTIDHVYFTACGGSQAVLMAGQYLFD
                     KELTVPCHVYTANEFNYAIPKGLSENSLVITCSHSGTTPETVEATKKAREFGAMTICL
                     SNEEGSPLWEAAEYPVHYDWGKDVDASDLNKGILYGLLFNILLVLDGSKKWETCLNEF
                     DKLNDLVIAEKSKFEITAKEWGKNQKRDKIIYTIGSGINYGEIYSTAACWFMEMQWIN
                     SNAIHSGEFFHGPFEITDYDVPFILVKSIGDTRFLDQRVEDFTKKFSNKLMVLDQADF
                     DLESIDSVAKEYIAAVLSGVVIRQMVEAIAFERGHSLDVRRYMWQMKY"
     gene            2263..2724
                     /locus_tag="ACG8ZV_002648"
     CDS             2263..2724
                     /locus_tag="ACG8ZV_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFS4997903.1"
                     /translation="MANEILINRRLQKMANQLFHIVITTHSTLCEGYLKATKLILMND
                     ATGISAVPFKENTSPDDFEESMKEIISQHHLQPLIILTDLIGGTPNNVSIKQLNNNRI
                     QIIAGINLPLLLELLMAQSAGKSIEEIDFKELLNNSQKSMVHINSLLKDVS"
     gene            2774..3238
                     /locus_tag="ACG8ZV_002649"
     CDS             2774..3238
                     /locus_tag="ACG8ZV_002649"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFS4997904.1"
                     /translation="MIKLVRVDHRLLHGQVIFSWTKQYDINHIIVADNKVPGDPMSVM
                     ALTIAKPADCKLDIVKISDVKGIMETSPNDNYMILIKGPKEAFELVQNLPEIKEINFG
                     GVSKKSESKQYGKAVFLTPEELEATKKILDQEVKIFVQQVPSSSIENVDFSK"
     gene            3252..4001
                     /locus_tag="ACG8ZV_002650"
     CDS             3252..4001
                     /locus_tag="ACG8ZV_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFS4997905.1"
                     /translation="MLLKAILLGLVGVVAVIDSRLIGRQNIGRPLILSTLAGLVLGDL
                     HTGIVLGASLELISMGFVSIGAAGPPNMQLGSIIATAFAILTNSSTETALTIAIPVAV
                     AGEFMSIIMRMIIAQFGHAADKAIENNKFRKAQIIHIYWSFIFNAFVYFIPIFLTVYF
                     GADVVADLVDKIPEMITDALTVSGNMLSALGFAMLLSTMLSKKLYPYFIFGFFIVAYS
                     GLSLIGVTIFAALIAFVMDQVKYGKREEAHG"
     gene            4001..4831
                     /locus_tag="ACG8ZV_002651"
     CDS             4001..4831
                     /locus_tag="ACG8ZV_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFS4997906.1"
                     /translation="MENSTEKKRLITKKDLNKMCLRSWTIMCSWNYERQMHMGFMYGM
                     APILNKVYKNDEEKKREAYTRHMAFFNCTPQMTSFIMGLCASMEEQNAQAEEGNFNTE
                     SISMIKTSLMGPFAGIGDSFFQGTLRIITFGIGLSFAKQGSILGPILAVGLFAIPSIL
                     AVFYGGKLGYESGNKYLTKLYQEGLMDRVMQFASIIGLAVVGGMVASMVPIVTPLKFT
                     TGGTELVLQDLLDSIIPGLLPLVCTLGIYKLIKKNVSTNMLLLGCILAGFVLSIIGIL
                     "
     gene            4831..5478
                     /locus_tag="ACG8ZV_002652"
     CDS             4831..5478
                     /locus_tag="ACG8ZV_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFS4997907.1"
                     /translation="MIKALIFDMDGVLIDSEIMYQKWVFNFLKQENLSYPLYSYQKKI
                     GTTASIFDDIEKYNEGCNSLELKGKFTKYWKSQKIDYLDIFPNILIEQLEWLKKKKIK
                     MAIASSSPMDTINEVVTTCKIESYFDCLISGRDLPESKPNPTIFLKASEQLRIPVEEC
                     LVIEDSYNGIKAGKRANMKVLAIKDKRFSQDVSLADDVIYDIKYLRQEVQVKFGI"
     gene            complement(5576..6352)
                     /locus_tag="ACG8ZV_002653"
     CDS             complement(5576..6352)
                     /locus_tag="ACG8ZV_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFS4997908.1"
                     /translation="MNFQDNRPLYLQVEASIRNDIREKKYLPGEQLPTEEELCKIYGV
                     SKITIRKAFKLLAESGTVERLRGKGTFVTQKKESLKLAGVHGFSDSLSTRGHKIRYTV
                     LHSKIIKADEFLANKLQINVTDRVYNIKRLMWEDGAPMGIDNFFASEEKFPTLFEKGS
                     QYTSLYKLLEDDYDVKATSSIMEINGLSATPELSDLLQCIVGDPLFILEKVGKDKNNQ
                     PFHYSQSTVRCDRISYVIEVTENITLDTVHKNDSDPKVID"
BASE COUNT         2172 a          950 c         1182 g         2196 t
ORIGIN      
        1 tggtacattg gtttagcaga ggacagttca cacattcttt tggattggat ttgtattctc
       61 ggtacccttc tcgagtaacc gttgaaaaag cgagcatttg atcttgcgga caaatataac
      121 aatcaaaata ctcgtcatag agaaactcat tttttgataa tagccccttt ttccctttgg
      181 gccttgaata aggcaaacaa ggtcgaaggt tcaaatgagt caaaaagtga acaaacttag
      241 gtgtcttata cccagcatca gcgacaacac aattgatttc aggaaaaagt ctcttcgatt
      301 gtttgacgag ctgaaaggcg acttaactgt catgaatatt tccaggagtg atgattgtgc
      361 taagaataaa tccattgtcg tcgcatgaag tatgggcaga ataagcaaat tgtttttctt
      421 gttcgccttt gacgtagtag ccgctttccg gatcagcttt acttattttt ctttctttca
      481 gcttcacttc cttttctaag tccaaagtaa aagggcgttt tccagcctct attcgttgac
      541 gattgatctc atcttctaat tcatcctgat aggctttcgc ttcatcatgg gtcatttctt
      601 tcgtaaactt atgtttattg gcgttagctt tgatgtgggt agaatctaga tgaaaattat
      661 cctctgttac aaaacctgct ttaactgctt gttctaaaat ataggcaaaa atatcctcaa
      721 acaccgtcgt ttctctaaat cggcgaacat aattctttcc aaaagttgag aaatggggga
      781 ttttctcttc gaaggagtag cctaaaaacc agcggtaagc gacattggta tcgacttcct
      841 taatggtttg tcgcatggaa cggataccga ataaatactg aataaacacc aatttgatca
      901 gaatcactgg gtcgatactt gggcgaccta aatcggagta agtggcttcg acgattggat
      961 aaataaattc aaaatcaagc gcggcatcaa tctttcgaac gagatgatct tgaggaacta
     1021 gatcatcaat cgtaagcatc gcaaattgat ttctaccatt cgtattgttt ttagacatca
     1081 tagctatcac tccttgcatt cgttttcata aatctattat aaaagaaaag actgtagaca
     1141 tcatccataa aatggacttt gtctacagtc tggcatttta ttatataaaa ttgttataaa
     1201 aaaatttttt tgaaaaatag tattgcaaaa taaagcaatt tcatagataa taggtattgt
     1261 aaagttatat gactttataa tacttattag agtgagggat aaagaaatga gacaactaca
     1321 caaagaacag attgaaacag caatggcagc gttaaaggaa aagacaattg atcatgtata
     1381 ttttacagca tgtgggggtt cacaagccgt tttaatggct ggtcaatatc tatttgataa
     1441 agaattaact gtaccttgtc atgtttatac tgctaacgaa tttaactatg ctataccaaa
     1501 aggattatct gaaaattctt tagttatcac ttgttcccat tctggcacaa caccagaaac
     1561 tgtagaagca acaaaaaaag caagagaatt tggagcaatg actatttgtt tatctaatga
     1621 agaaggatct cctctatggg aagcagctga atatcctgtt cactatgatt ggggtaaaga
     1681 tgttgatgct agtgatttaa ataaaggaat tctttatggt ttattattta atattttact
     1741 tgttttagat ggctctaaaa aatgggaaac ttgcttgaat gaatttgata agttaaatga
     1801 tcttgttatt gctgaaaaga gcaaatttga aataactgct aaagaatggg gtaaaaacca
     1861 aaaacgagat aaaattattt acacaattgg tagcggtatc aattacggag aaatttactc
     1921 cacagcagct tgctggttca tggaaatgca atggattaat tctaatgcta ttcattctgg
     1981 ggaatttttc catggtcctt ttgaaatcac tgattatgat gtaccattca tcttagtgaa
     2041 aagtattgga gatacaagat ttttagatca acgggtagaa gacttcacta aaaaattcag
     2101 taataaatta atggttttag accaagctga ttttgactta gaatctatag atagtgtagc
     2161 gaaagaatat attgcagctg tacttagtgg cgttgttatt cgccaaatgg tagaagcgat
     2221 tgcttttgaa agaggccatt ccttagatgt tagacgctat atgtggcaaa tgaaatatta
     2281 attaatagga ggttgcaaaa gatggcaaat caattatttc acattgtgat tacaacacat
     2341 tctacccttt gtgagggtta tttaaaggca acaaaattaa ttttaatgaa tgacgccaca
     2401 ggtattagtg ctgttccatt taaagaaaat actagtccag atgattttga ggagagtatg
     2461 aaagaaataa ttagtcagca tcatttgcaa cctctaatta ttttaacgga tttaattgga
     2521 ggaacaccta ataatgtttc tattaaacag ttgaacaaca atagaattca aattattgct
     2581 gggattaatt tacctctttt actggagtta ttaatggccc agtcagctgg taaatctata
     2641 gaagaaatag attttaagga attactgaat aactctcaaa aaagtatggt tcatattaat
     2701 tcgcttttaa aagatgtcag ttaaggtggc aatttctatt ctataaattt taaaaattga
     2761 aggaggaaat agaatgatta aattagtgcg tgtagaccac agattacttc atggacaagt
     2821 aatattttct tggactaaac agtatgatat taaccatatt attgtggctg ataacaaagt
     2881 tccaggagat ccaatgtctg tgatggcttt gacaattgct aaacctgctg attgcaaatt
     2941 agacattgtt aaaattagtg atgttaaagg gattatggaa acatccccaa atgataatta
     3001 catgatttta attaaaggac ctaaggaagc ttttgaatta gttcaaaatt taccagaaat
     3061 taaagaaatt aattttggcg gtgtgtctaa gaaaagcgag tccaaacaat atggaaaggc
     3121 agtcttttta actcctgaag aattagaagc cacaaaaaaa attcttgatc aagaagtgaa
     3181 aatatttgtg caacaagtcc catcttcaag tattgaaaat gtagatttta gtaagtaagg
     3241 ggggaaaata aatgttatta aaagccattt tattaggttt agttggtgtg gtagctgtta
     3301 ttgactccag gttaattggt cgacaaaata ttggtagacc actaattttg agtacacttg
     3361 ccggacttgt gctaggtgac ttgcatacag ggattgttct tggggcatct ttagaattaa
     3421 tttctatggg attcgtctca attggggcgg ctggacctcc taatatgcaa cttggtagta
     3481 ttattgccac tgcttttgca attttaacta atagtagtac agaaacagcc ttaacaatag
     3541 ctatcccagt ggctgtagct ggtgaattta tgagtattat catgcgcatg ataattgctc
     3601 aatttggaca tgctgcagat aaagccattg aaaataataa atttagaaaa gctcaaatta
     3661 ttcatattta ttggtcattt atttttaatg cttttgttta ctttattcca atctttttaa
     3721 cagtatattt tggtgctgac gttgtggcag atttagtaga taaaattcca gaaatgatta
     3781 cagacgcctt gactgtctct ggaaatatgc tttccgcatt agggtttgca atgctattaa
     3841 gcacaatgtt gagtaaaaaa ttatatcctt actttatttt tggattcttt attgttgcct
     3901 attcaggtct ttcactaatt ggcgtgacaa tttttgcagc tctgattgcc tttgtaatgg
     3961 atcaagttaa atatggaaaa agagaagagg cgcatggtta atggaaaata gtacagaaaa
     4021 aaaacgttta atcacaaaaa aagatcttaa taagatgtgt cttcgttcat ggacaatcat
     4081 gtgttcgtgg aattatgaaa gacaaatgca tatgggattt atgtatggga tggcgccaat
     4141 tttaaataaa gtttataaaa atgatgaaga gaaaaaaaga gaagcttata ctcgtcatat
     4201 ggcatttttt aactgtacgc ctcaaatgac ttcatttatt atgggacttt gtgcttctat
     4261 ggaagaacaa aatgctcaag cagaagaagg aaactttaat actgaatcta tctccatgat
     4321 taaaaccagt ttaatgggtc cttttgctgg aattggtgat tcatttttcc aaggtacttt
     4381 aagaattatt acatttggga ttggattgtc ttttgctaag caaggtagta ttttaggacc
     4441 gattttagct gttggccttt ttgctatacc ttctatttta gctgtttttt acggcggtaa
     4501 attaggatat gagtctggca ataaatacct tactaaattg tatcaagaag gtcttatgga
     4561 tcgagtaatg caatttgctt ctatcattgg tttggctgta gtaggtggaa tggtggctag
     4621 catggtgcca attgtcaccc ctttaaaatt cactacaggg ggaacagaac ttgttttaca
     4681 agacttactt gattccatta ttcctggatt attaccactt gtatgtactt tgggaatata
     4741 taaattgatt aagaaaaatg ttagtacaaa tatgctctta ttaggttgta ttttggcagg
     4801 gtttgtttta agtataatag gtatcttata atgattaagg ctctaatttt tgatatggac
     4861 ggagttttaa ttgatagcga gattatgtat caaaagtggg tatttaattt tttaaaacaa
     4921 gaaaatttaa gctatccttt gtattcttat caaaaaaaga ttggaactac agcaagtatt
     4981 tttgatgata tagaaaagta caatgaggga tgtaacagtt tagaattgaa gggaaaattt
     5041 actaaatatt ggaaatcgca aaagattgat tacttggata tttttcctaa tatactaatt
     5101 gaacagcttg aatggttaaa aaagaaaaaa ataaaaatgg caattgcttc ttccagtcca
     5161 atggatacta taaatgaagt tgttaccact tgtaaaatag agtcatattt tgattgttta
     5221 attagcggaa gagatttgcc agaaagtaaa cctaatccta ctatattcct taaagcttca
     5281 gaacagctca gaattccagt tgaagaatgt ctggtgatag aagattctta taatggtata
     5341 aaagctggta aaagagcaaa tatgaaggtt cttgcaatta aagataaacg tttttctcaa
     5401 gatgtaagtc tagcagatga tgttatttac gatattaaat atctgcgaca agaagtacag
     5461 gtgaaatttg gaatataaat aagttttttg atgtatttag agaatattag taaaaataaa
     5521 aatcatgccc aaatctaatc aaaattgatt gctttgggta tgatttcttt taatatcaat
     5581 ctattacttt aggatctgaa tcatttttat gcaccgtatc taaagtgata ttttctgtga
     5641 cttcaataac ataactaatt ctatcacaac gaactgtgga ttgagaataa tgaaatggtt
     5701 gattattttt atctttgcca accttttcta aaataaatag cggatctcct actatacatt
     5761 gcaataagtc ggaaagctca ggtgttgcag ataaaccgtt tatttccata atagagctcg
     5821 tagctttgac atcatagtca tcttctagaa gtttatataa tgaagtatat tggctacctt
     5881 tttcaaataa agttggaaat ttttcttctg atgcgaaaaa attatcaatt cccatcgggg
     5941 caccgtcttc ccacattaaa cgtttaatat tgtaaactct atcagttaca ttgatttgta
     6001 atttattagc taaaaactca tcagccttta taattttaga atgtaaaaca gtatatctaa
     6061 ttttatgtcc tcgggtagaa agagaatcgc taaatccatg aactccagct aattttaaac
     6121 tttctttttt ttgagttaca aaggtccctt tcccccttaa tcgttcaact gttccacttt
     6181 ctgctaaaag tttaaaagct tttcgaatgg taatcttact tactccataa attttacata
     6241 attcttcttc tgtaggtaat tgctctcctg gaagatattt tttttcacga atatcgttac
     6301 gtatagaagc ttctacttgt aaatataatg gtctattatc ttgaaaattc atagtacact
     6361 ccctaaaaag ttatacttca ttatatcaca atttattaaa acgtcgattg taaaattaag
     6421 ctagacaact aaaaagatca tttgtgctac actcaaaata gttccgacca aagaattaat
     6481 aaggagtgag tacaaatgac
//
LOCUS       DAZULR010000094         6392 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.099, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000094 DAZULR010000000
VERSION     DAZULR010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6392
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.099"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..382
                     /locus_tag="ACG8ZV_002654"
     CDS             <1..382
                     /locus_tag="ACG8ZV_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HFS4997909.1"
                     /translation="NSLRYLEFREGAFDFQTSQQNLLTIPGAMSPTEIFKMFEMGADI
                     VKVFPANCLGPEYFNQVQAPLGSLPLMAVGGVDQTNAQNYLNNGASYVGIGSKFFEKS
                     AVHQLNYERLMELAESFIDSLRVE"
     gene            complement(776..1783)
                     /locus_tag="ACG8ZV_002655"
     CDS             complement(776..1783)
                     /locus_tag="ACG8ZV_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFS4997910.1"
                     /translation="MVTIRDIAKKSGYSTATISRLFKGDESLSITSDTKNKIIVTAKS
                     LGYDLTKIKTTLYKIAILFWISEEQLKKDVYYQHVKDDLKNYSKKANLDLIFISKNDG
                     VKSIPDDITGFIAIGQLTKKELYYLNQKGYKGVIRGINPLPEHFDTVEPDFHEMARQA
                     INYFINEGFTKIGFIGGNFFNLETGKEEIDSREYAFRYHLEKSGLLNEKYIFSQGSFT
                     VDEGYQLTLKMKAELNEDMPEACFIPSDTIAAGVLQGCHELGINIPKDMAVISINDDD
                     IAKFVAPPLTTFKIDIEEIAKTCVDLLSDQLVYSRDISKKTLIGAKLTVRKSFIPKEE
                     V"
     gene            2250..3656
                     /gene="lacG"
                     /locus_tag="ACG8ZV_002656"
     CDS             2250..3656
                     /gene="lacG"
                     /locus_tag="ACG8ZV_002656"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HFS4997911.1"
                     /translation="MNYKTLPEDFIMGGATAAYQAEGSTKEGGKGQVAWDTFLVEKGR
                     YTADPASDFYNQYPVDAELCKKFKIDSIRMSIAWSRIFPKGYGEVNQTGVEYYHKVFA
                     ELNKHGIIPFVTLHHFDTPKELFDNGDFLNRENVEHFVNYAQFCFDEFSEVHYWSTFN
                     EIYPVASNQYLIGSFPPEVQFDIEKTVTCLHNMMYAHAKTVNIFKDGGYKGEIGVVHS
                     LETKYPASDKEEDKHAAKLDDALSIKFLLDATYLGYYSDETMAHINEILAANGQSADI
                     DSNDFREMKKAANRNDFLGINNYGSHWVKEYKGESTLHYNTTGEKGSQVYCIKGIGER
                     IVREDLPKTDWDWIIYPKGLYDLLVRIQDEYPNYNKIYITENGLGYKDNFEDGIILDD
                     DRIDYLRQHFNAISDAIKMGVNVKGYFIWSLMDVFSWVNGYTKRYGLFYVDFDTQKRY
                     PKESAYWYKFVSETKTII"
     gene            3679..4002
                     /locus_tag="ACG8ZV_002657"
     CDS             3679..4002
                     /locus_tag="ACG8ZV_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFS4997912.1"
                     /translation="MDRKELQLLGFEIVAYAGDARSSLLTVLKEVREGNFDNVERLLA
                     DADENLTLAHNSQTKCLAEEASGNEMEVGVIFIHGQDHLMTTILLRELINDFVELYKE
                     KFAKA"
     gene            4013..5695
                     /locus_tag="ACG8ZV_002658"
     CDS             4013..5695
                     /locus_tag="ACG8ZV_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HFS4997913.1"
                     /translation="MNTIIKQIEKGKPFFEKISRNIYLGAIRDGFLTAMPAILFSSIF
                     IMIAAVPEVFNVTLPEAFSTWLWKVYGYSMGLVGLLVVATTARCLANSMNRQLSDSGK
                     QINEVSVMLASICGFVMMAADQIDGGIATDYLGTKGLLAAFVSAFVTVNVYKFCVKRD
                     LTIRMPKEVPGTITQMFRDIIPFSIAVFIAVLIDTGVRQFFGTSFAAGVIQLLQPLFS
                     AADGYVGIAIIWGAMAMFWFVGVHGPSIVEPAIAAIIYANVETNFELFKNGAQASKVL
                     TVGLGNFVGTMGGTGATLVVPFLFMLFAKSKQLKAVGKASFIPVSFAVNEPLLFATPI
                     ILNPYFLIPFLLAPIANVWIFKLFVDVLGMNSFISVLPWATPAPIGLVLGTGFSVLAI
                     VLAVVLIVVDAIIYLPFVKAYDSELVEQELKNIAAEEVKEELVEEIQEVGATAAVIVD
                     EAKASVGEGKRVLVLCAGAGTSAMLANALEEGAKETGVNLSAKAGAYGSHYDMMKNFD
                     LIVLAPQVNSYLDDLRKDADKLGIKVIATKGAEYINLTRDPKGAVDFVLKQF"
     gene            5901..6392
                     /locus_tag="ACG8ZV_002659"
                     /pseudo
     CDS             5901..6392
                     /locus_tag="ACG8ZV_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2034 a          981 c         1294 g         2083 t
ORIGIN      
        1 taacagccta agatatttgg agttcagaga gggcgcgttt gattttcaaa cttcgcaaca
       61 gaaccttcta acaattcctg gggccatgtc gcccacagag atattcaaaa tgtttgagat
      121 gggtgctgat attgttaagg tgttccccgc caactgtctt ggaccggaat atttcaatca
      181 agtgcaagcc cctttaggaa gtttaccttt gatggctgta ggaggggtag atcagactaa
      241 tgcacaaaac tatttgaaca atggagcctc ttatgtagga attggttcaa aattttttga
      301 aaaaagtgct gttcaccaac taaattacga gaggctaatg gagttggctg aatcttttat
      361 agatagttta agagttgaat agaacccatt tgcggaatac aacttgtttt ataatatggc
      421 gttatctgta taaaacatag tatcacagtg aatgagattg aactggtaga ttgatttttc
      481 gaccagttct ttttgcgcgc tctgatgctt gatatattcc caacgagata aaaaatcccc
      541 caagatacta agatgaagcg tttatccaac ctcatactta gataaaaagg aggaaatgtt
      601 ctgaatgata aacaaaaatt agcgcgcaca atttggcgat gaaaaaatca tattgtattt
      661 acgtcaaaat atcaccatca aattatttat ggaaaacata ataggcataa acccgattgc
      721 tcggctacta tgtggacaca attatagttt taaagataag tttcaattac ttattttaca
      781 cctcttcttt agggataaaa cttttcctaa cggtcaattt tgcgccgatt aatgttttct
      841 ttgatatgtc ccgcgaatat accagttgat cacttaataa atctacacag gttttagcta
      901 tctcttcgat atctatctta aaagttgtaa gtggtggtgc aacgaatttt gcgatgtcgt
      961 catcattaat acttattact gccatatctt tagggatgtt aatacccaat tcatggcagc
     1021 cctgaagaac gccggcagct atagtgtcag atggtatgaa acatgcctcg ggcatatctt
     1081 catttaactc agctttcatt ttaagagtta attgataccc ttcgtcaaca gtaaatgatc
     1141 cttgggagaa aatatacttt tcattgagta gtccgctctt ttctaaatga tatcggaagg
     1201 catattcacg gctatcaatc tcttctttac ccgtttctag gttaaagaaa tttcctccaa
     1261 taaatccaat ttttgtgaaa ccttcattaa taaagtagtt aattgcttgt ctggccattt
     1321 cgtggaaatc aggttctaca gtatcgaagt gttcaggtaa tgggtttatt cctcggatta
     1381 cccccttata ccctttttga tttaagtagt acaattcctt ttttgtcaat tgtcctattg
     1441 cgataaatcc agtaatatcg tcaggaatgc tttttacacc atcgttttta gagatgaaaa
     1501 tcaaatctag attagctttt ttactataat ttttcaaatc atctttgaca tgttgatagt
     1561 agacatcctt ttttaactgt tcctctgaga tccaaaaaag aatggcaatc ttgtacagag
     1621 tagtcttaat ttttgtcaga tcatatccta aagatttggc tgtaacgatt attttgtttt
     1681 tagtatcaga tgtaatagag agtgactcat cacctttaaa aagtcttgat atagtagccg
     1741 ttgagtaacc agattttttt gcaatatctc taatagtaac cattgttcat cctcctaggg
     1801 atataataat ccttttcttt gttaaagtaa atcgaaactg ctcttttagt aacttaaatt
     1861 actttttcta gcaggaaacg aaactctgat atcagcagag agcctaatcc attaacagag
     1921 aagattgaat cgataatgga tagccacttg gagaatgatt agtaggtggg attgatttta
     1981 gtgggaatca gtccgttttc ttgtttcgtg taaattaaat tagtaaaaag ataaatttat
     2041 tttacaaaaa aacgtttaca aaacggtttt tgaatggtat atttatttta catcaaggga
     2101 tataagtgct tgtatatcgc aataaaatag atattcgagg tcggtttttc gttgtgtaaa
     2161 aaaatttact tatacatgtt aaaattatgc tgaggtgatt tatggattat tggcatattg
     2221 atcaaactaa ttttcaagga gagattaaaa tgaattataa aactttacca gaagacttta
     2281 ttatgggagg agctacggca gcttatcaag cagaaggctc tacaaaagaa ggtggaaaag
     2341 ggcaagtagc gtgggatact ttccttgtag aaaagggacg ctatactgct gatccagcta
     2401 gtgattttta taatcaatat ccagttgatg ctgaattatg caaaaaattt aaaattgata
     2461 gtattaggat gtctattgca tggagccgta tttttccaaa aggctatggg gaagtgaacc
     2521 aaacaggagt ggaatattat cataaggtat ttgctgaatt gaataagcat ggtattattc
     2581 cttttgtaac tcttcatcat tttgataccc ctaaagaact atttgataat ggagattttt
     2641 taaatcgaga aaatgttgaa catttcgtaa actatgcaca gttctgtttc gatgaatttt
     2701 ctgaggttca ttattggagt acatttaatg agatttatcc agttgcttca aatcaatatt
     2761 tgatcggatc gtttcctcca gaagttcaat ttgatataga gaagactgta acttgtttac
     2821 acaacatgat gtatgcgcac gcaaagacag taaacatttt taaagatggt ggatataaag
     2881 gggaaattgg tgttgttcac tcgctagaga caaaatatcc agcaagtgac aaagaagaag
     2941 ataagcatgc tgcgaaatta gatgatgcgt tatcaattaa gttcttatta gatgctactt
     3001 atttagggta ttactcagat gaaacaatgg cacatattaa tgagatttta gcagcaaatg
     3061 ggcaatctgc agatattgat tctaatgatt ttagagagat gaaaaaagca gcaaatcgaa
     3121 atgattttct tggtatcaat aactatggta gccattgggt taaagagtac aaaggagaaa
     3181 gcacacttca ctacaacact accggagaaa aaggtagcca agtctattgc attaaaggga
     3241 ttggcgagag aatcgtgcgt gaggatcttc cgaaaaccga ttgggattgg atcatttatc
     3301 caaaagggtt atatgattta cttgtacgaa tccaagacga atatccaaat tataataaaa
     3361 tatacattac tgaaaacggg ctagggtata aggataattt tgaagatggg attattctag
     3421 atgatgatcg aatcgattat ttacgccagc attttaatgc gatttccgat gctatcaaaa
     3481 tgggagttaa tgtaaagggg tatttcattt ggtcattaat ggatgttttc tcttgggtta
     3541 atggatacac taagcgttat ggactattct atgtagattt cgatacacaa aaaagatatc
     3601 cgaaagagtc tgcatattgg tataaatttg ttagcgaaac aaaaacgata atataaaaat
     3661 agttaggagg gcaaggaaat ggataggaaa gaattgcaat tattaggatt tgaaattgtt
     3721 gcttatgcag gagatgccag aagttcatta ttaacagtgt tgaaggaagt gagagaaggt
     3781 aattttgata atgttgaacg attattagcg gatgctgatg aaaatttaac cttagcgcat
     3841 aactcacaaa cgaaatgttt agctgaagaa gcgtcaggga acgaaatgga agtaggcgta
     3901 atttttattc atgggcaaga ccatttaatg acaacgattc tattaagaga acttatcaat
     3961 gattttgttg aattgtacaa agaaaaattt gctaaagcat aggagaagaa aaatgaatac
     4021 gattattaag caaattgaga agggaaaacc gttttttgaa aaaatctcac gtaatattta
     4081 tttaggggca attcgcgatg gctttttaac tgctatgcca gctattctat tttcaagtat
     4141 ttttattatg attgcggctg ttccagaagt atttaacgtg acgttaccag aggcattctc
     4201 gacgtggctt tggaaagttt atggttattc aatgggatta gttggtcttt tggttgttgc
     4261 tacaacagct cgatgtttag ctaattcaat gaaccgtcaa ttatctgatt caggtaagca
     4321 gattaatgaa gtttctgtta tgttagcgtc aatttgtggt tttgtaatga tggcagctga
     4381 tcaaattgat ggtgggatag ctactgatta tttagggaca aagggattat tagcagcttt
     4441 cgtttctgcg tttgttactg taaatgtgta taaattctgt gttaaaagag atttgacgat
     4501 ccgtatgcca aaagaagttc ccggaacaat cacacagatg tttagagata ttatcccctt
     4561 ttcaattgca gtatttattg ccgttttgat tgatacggga gttcgtcaat tttttggaac
     4621 atcatttgca gcaggtgtaa ttcaattatt gcagccatta tttagtgctg ctgatggata
     4681 tgtcggtatt gcaatcattt ggggagccat ggcaatgttc tggtttgttg gtgttcatgg
     4741 accatcgatt gttgaaccag cgattgctgc aattatttat gcgaacgtag aaactaactt
     4801 tgaattattt aaaaacggtg cacaagcctc aaaagtatta acagttggtc taggaaactt
     4861 tgttggaacg atgggtggta ctggagcgac actagttgtt ccttttctgt tcatgttgtt
     4921 cgctaaatca aaacaattga aagcagttgg taaagcttca tttattccag tttcgtttgc
     4981 ggtaaatgaa ccgttactat ttgctactcc tattattttg aatccgtact ttctaattcc
     5041 atttttatta gcaccaatcg ctaacgtatg gatattcaaa ctttttgtcg atgtcttggg
     5101 gatgaatagc tttatatccg tattgccttg ggcgacgccc gcaccgattg gcttggtttt
     5161 aggaaccggg tttagtgtgt tggcgattgt attagcggta gtattgattg ttgtcgatgc
     5221 gattatttat ttaccttttg ttaaggccta tgattctgaa ttagtagaac aagagttaaa
     5281 aaacattgct gcagaagaag taaaagaaga attggtcgaa gaaatccaag aagttggtgc
     5341 aactgcggca gttatagttg atgaagcaaa agcatcggtt ggtgaaggaa agcgcgtttt
     5401 agtactttgt gctggtgccg gaacgagtgc aatgttggct aatgcattag aagagggcgc
     5461 aaaagagaca ggtgttaatc tttctgctaa agcaggagct tatggttctc attatgatat
     5521 gatgaaaaat tttgatttaa tcgttctagc acctcaagtg aattcctatt tggatgatct
     5581 ccgtaaagat gcagacaaat tagggataaa agtaattgca actaaaggtg cagaatatat
     5641 caatttaaca cgtgatccta aaggagcagt tgattttgta ttgaagcaat tttagagctt
     5701 gcttagatta ataaagcgct agccaactta gctagcgttt tatcttaaac acaatggtaa
     5761 gcgctatctt tttttgctgt ttaaatttcg ggtattcttt ttgaggcgtc gattgtaaaa
     5821 ttaagctaga caactaaaaa gatcatttgt gctacactca aaatagttcc gaccaaagaa
     5881 ttaataagga gtgagtacaa atgacctaca cccatcttac aacagacgaa ctagtaatca
     5941 tagagtctta tttcaatatc gagaaacctg tcgctcttgt cgcacaaagt ttaaatcgct
     6001 ctagacaaac catttataat gtttattcgt ttctcaaaca aggaaaaaag tgctagatta
     6061 ttaccgtcaa tacaaacaaa ataaatctcg ttgtggacga cgttcaaccg ttttatctga
     6121 tgaacaatca acatatgttc aagaaaaggt agctcaaggg tggtcacccg atgtgattat
     6181 cggccgtggc gagtttccaa ttgattgttc tgttcgtaca ctctatcgga tgtttaaaaa
     6241 aggccttttt gacacacagt cgttacctat gaaggggaaa cgtaaaccga ataatcatca
     6301 agaaaagcgt ggaaaacagg cctttcgcag aacgattcat gaacggaaca gtctctatcc
     6361 acacctgact aaagaatttg gtcatctcga ag
//
LOCUS       DAZULR010000095         6334 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.100, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000095 DAZULR010000000
VERSION     DAZULR010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6334
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.100"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(99..1229)
                     /locus_tag="ACG8ZV_002660"
     CDS             complement(99..1229)
                     /locus_tag="ACG8ZV_002660"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HFS4997914.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1878..3080)
                     /locus_tag="ACG8ZV_002661"
     CDS             complement(1878..3080)
                     /locus_tag="ACG8ZV_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFS4997915.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="ACG8ZV_002662"
     CDS             complement(3140..3343)
                     /locus_tag="ACG8ZV_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HFS4997916.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4552)
                     /locus_tag="ACG8ZV_002663"
     CDS             complement(3485..4552)
                     /locus_tag="ACG8ZV_002663"
                     /inference="COORDINATES: protein motif:HMM:NF014537.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFS4997917.1"
                     /translation="MLDSLQEEVVPVNRVLIDYLTIHFFSNQHLKLIEEIIEMPIERF
                     EELDYAPKGYIGQYVWNQVITIRYSIDDAVKGTVMEFSGQGCKHLARWLKTRKTNWQQ
                     FFRKVLDYQGNFTRIDFTLDDFVGSLSIPELKHKVILGHVWTTFQVSESHGGTDIINN
                     ESNGETLYLGSKKSQCRFCFYQKDHEQRKRRGIPLEEAKVKNRFELRYRKEKAQSLAK
                     IISKTHDLTKLFFELLNGAICFYDRDPNDLGAKVDAKWAAFISNYGAITISLDTIPQS
                     FEKTMSWLIHGVSPSLVFIAQVDQTFHSSLLPLIIEQGEMNPRQIKLLQNMKADPEYY
                     QEEVEYYERKLQSISNEKTSY"
     gene            complement(4610..4717)
                     /locus_tag="ACG8ZV_002664"
     CDS             complement(4610..4717)
                     /locus_tag="ACG8ZV_002664"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4997918.1"
                     /translation="MNQVNQHDLGEAIRVSREERGWTQRYLAEKVGISR"
     gene            4880..5692
                     /locus_tag="ACG8ZV_002665"
     CDS             4880..5692
                     /locus_tag="ACG8ZV_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4997919.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6066..6257)
                     /locus_tag="ACG8ZV_002666"
     CDS             complement(6066..6257)
                     /locus_tag="ACG8ZV_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997920.1"
                     /translation="MKQKFFIAIIATKKFHRGKRFGQKWKFPPKVTAPQLKSIKELEF
                     ENALVICMTCTDEVFRKHF"
BASE COUNT         1889 a         1300 c          998 g         2147 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag aaaa
//
LOCUS       DAZULR010000096         5851 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.101, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000096 DAZULR010000000
VERSION     DAZULR010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5851
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.101"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(96..437)
                     /locus_tag="ACG8ZV_002667"
     CDS             complement(96..437)
                     /locus_tag="ACG8ZV_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 family protein"
                     /protein_id="HFS4997921.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQKLTDNPIGFGLLPEDDEGNEWFKMTLTDDNGDELSVEDTWSYLSDYIVSV
                     EIIEFVADKEE"
     gene            complement(424..753)
                     /locus_tag="ACG8ZV_002668"
     CDS             complement(424..753)
                     /locus_tag="ACG8ZV_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997922.1"
                     /translation="MIQKFAKMSKTAWIEKLENDLSVMRLAPKKFKREIAEKEAILSV
                     LNAVDDKCPVKISFSDIATIIEGIYYGEVDEEISSTKDLLDFLDKNKDTFIVLTDYEE
                     VTTNEKL"
     gene            complement(1344..1676)
                     /gene="traE"
                     /locus_tag="ACG8ZV_002669"
     CDS             complement(1344..1676)
                     /gene="traE"
                     /locus_tag="ACG8ZV_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraE"
                     /protein_id="HFS4997923.1"
                     /translation="MSYTGILSLEDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIS"
     gene            complement(2513..3553)
                     /locus_tag="ACG8ZV_002670"
     CDS             complement(2513..3553)
                     /locus_tag="ACG8ZV_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HFS4997924.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDSTVIAKIANTAKPRKINDST
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMQEDSINTFVPENVLNLIKTFSSSYSEAQQTVQTIHNAKKKAEELEQTIVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(3902..4228)
                     /locus_tag="ACG8ZV_002671"
     CDS             complement(3902..4228)
                     /locus_tag="ACG8ZV_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997925.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNYKPKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(4215..5003)
                     /locus_tag="ACG8ZV_002672"
     CDS             complement(4215..5003)
                     /locus_tag="ACG8ZV_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFS4997926.1"
                     /translation="MARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVDIDPQG
                     NATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAEREFTQVG
                     SEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLKGLIKL
                     SETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTTAATEISRVIGAKIFKTYIRRT
                     ITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            5334..>5851
                     /locus_tag="ACG8ZV_002673"
     CDS             5334..>5851
                     /locus_tag="ACG8ZV_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HFS4997927.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMDATYIPLKRQT"
BASE COUNT         1810 a         1078 c          817 g         2146 t
ORIGIN      
        1 aaattcctta ctcaatgcct aaggtaatac taccttttta ttattcgtcg tgactccttc
       61 taagccttta tctgtaaaat ttattcctcc agtttttatt cttctttatc cgctacaaat
      121 tcaatgattt caacgctgac aatataatca ctcaaatatg accaagtatc ttcaacagat
      181 aattcgtctc cattatcatc cgtaagcgtc attttaaacc attcattacc ttcatcatct
      241 tcaggtagca agccgaatcc aattggatta tcagtcaatt tttgatcgta taaatcatcc
      301 tcgtctaatg ctaaaacatc taatccttta caatttccgc ctcttctaaa cgtcacaaat
      361 cctttgtaat cccaacgttg gaaagaaacc ttaatcgtat gtgtgcccaa tcgtatattc
      421 ggatcataat ttttcatttg ttgtaacctc ctcataatca gttagtacta taaaggtatc
      481 tttgttttta tccaaaaaat ctaataaatc ttttgtagaa gatatctctt catcaacttc
      541 accataataa ataccttcga taattgttgc tatatctgaa aaactaattt ttactggaca
      601 tttatcgtct accgcattca ataccgacaa aattgcttct ttttctgcaa tctctcgttt
      661 gaatttcttt ggagctaatc gcatgacact caagtcattt tcaagctttt caatccatgc
      721 agttttactc attttcgcaa atttttgaat cattcctcta ccacctttgc tatctactaa
      781 attagtttta cttcataacg aatatcttta tcgtttttcg ttcactcaaa aatatataaa
      841 ataaatcgac tcgtttatgg cgtccgaaac gagaaaccct agtagacagc ggtaaatgct
      901 cgattgatcc aatgatcaac gtcctcgcaa gtatctacat gtactgcagc acacgacaca
      961 atttcttgtg cgtcctcccc attacgagaa gacctactcc ttattccatg agtttgcgtc
     1021 aaagcctaga tcccttagta gctgctcatg attaatctag gcgctattct aacttgtcta
     1081 acttctaaat tccctcttgt ttactctgtg catattattt acacaaattc atttcaccac
     1141 tatccaaaca agggcattta ctcgattgac caatttttta cgttaccaat cgtaaaaacc
     1201 taccccgtca ctccccgaag ggaattgttg atagatcaag tctactcctt atttttctag
     1261 tgattctaag ttcctttaga agtctcgaca atattttcaa gcaagcgaaa aacgataaaa
     1321 tacaagttat gagaatgatc aattcagctg attaaacgcc ccatcccttt tgcggtacaa
     1381 cgcaagactc cattttttct tcgaccaatc agtacaccgt tttggtcata aacatgtttg
     1441 attgttggat atagctcttt taaagggata ggatctttta aaattatttg tttttgtttc
     1501 ccaatgtaat aaatcatttc ttctgagact ttgtctttct ggattatata tttcttacac
     1561 tgcacaacgg ttttactttg accagttgat agtttcttcg tgatcttttc tgtagcggta
     1621 caccgtttac cgtagtgaca aatatcttcg agactcaaaa ttcctgtata tgacataaaa
     1681 taatccaccc acttacttta aatattttta acaagttttt cttgttattt ttcaaaaata
     1741 gagaattgat tttcgttcat gacaaacaaa aaagagggaa cgcattcaaa catgcgttcc
     1801 ctctaatttc agcgttcgtc atacggcaaa gagccccacg gacattttta taacattatg
     1861 cttaggcata gattcatcgt aatatcacgt atttttaacc ttaacacagc caaaaaaagt
     1921 ggtatcactt ttgaatatct gttatactaa atccgttacg ggtaataccg taacactgaa
     1981 aggtaaacgc attaaggggt atagacttaa tgccacctgt ggacgtcgac gaaggttacc
     2041 agccttccga gtctcacagg gcctttcttt tttttgtatt ttcaattgtc caaatttatc
     2101 gtccaaaagt gcagaacgaa aatcaattca tcacaagcat agcagacaat taaatttaaa
     2161 acaactaaaa atatacaaaa aagtgtaatt gaatattagc agcactgcct gaaaagaagt
     2221 aatatcaggc ttttcagctt ggggaaataa gtgaattacc tctcttcatg aattattata
     2281 actcaaaaaa gcacatatgc aaacactagt tccctatttt tttgagtgaa aaataactaa
     2341 aatatctaac gattatgaat ttaaaaccta cgattgtgat tgttttcata aacttttaat
     2401 ctaaaaactc cggaatacta actatttatt tgtaatattt gtaataaaat taaaatcata
     2461 aaaaagttct aatttaaaat tgatcatttt tatagtaatt gctttttatc aactactcta
     2521 accaattttc cgtactaact gttggtaatt cgttaaatgt ttctctttgt tcgtttgcaa
     2581 gctttgccgc aatagctttt tcgacaaacc aattttttac ataaacgaaa attagattct
     2641 gcaaattgtt tactttttca gttttttgtt tttgataagc tttcagtaaa gtcatatata
     2701 atcctttgtc agcatcaatt ccataagatt ccagttcttc ataaacgaca atagtttgct
     2761 ctaattcttc agcttttttc tttgcattat gaatagtttg gacggtttgt tgagcttcac
     2821 tgtaacttga agaaaatgtt tttatcaagt ttaatacatt ttctggtaca aatgtattta
     2881 tactgtcctc ttgcatgatg tcgacgaagt tatctagcaa aacttgattt tgtaactggt
     2941 cagtttcagt gtctattatg tgtctattag tgtctataga attagaatag aatagattgt
     3001 ctgcgatttt cgcaattacg gttgagtcct tgatatgact ggattttgcc gtatttgcga
     3061 ttttcgcaat tacggtagaa tcattgattt ttcgcggttt tgccgtattt gcgattttcg
     3121 caattacggt ggaatcagta ttgtcttcct cttccatgat tttaaagacg tcttgattcg
     3181 taacttctgg cttgcctaag tacaataaat taggcataga ttcaatctta ccatcacgtt
     3241 tatttactct tcctctcttc tgtttcagaa gacctgcttt ttctaattct tttttgatct
     3301 tagatacttt accttcgcgg cattgtaaca atttcattaa ttcttcaact gtgaatatga
     3361 agaatatatt atcatcagaa tctacccagt tatttttgac tgaataatca aatcgatctt
     3421 taagtagcat ataagcaatt tttgcatcat ttgaaagatc catgtatttt tcgttagtaa
     3481 aaaatacctt aggcatttga taatattttt cacgataaat ttcttttgat ttgtaataat
     3541 taaaatcatt catagccaat cctctttctg taggatagcg ttttgttcaa aactatgtta
     3601 caatgaatta aacaaatata tctatccact atatattttt ctactgctga taagtcgcca
     3661 aactttgtta aagcagtagt ctttttttat ctttttttag tttaccttaa aaaataaatt
     3721 aaagcaaacc gctctatttc agggtttaag ctcatggtaa ctatatcacg atattacaat
     3781 aacattatat cacgatatcg taatattaca atatgaagat aagcgactta tcagctttga
     3841 tactactgat ttttataaaa aaaatatcac gatattatga tatcgtgata ttgaatgtaa
     3901 attaaatttt attttgtttc tttgctagtt tatatccttc aatcaagtat tcttcaggta
     3961 tggattttaa tagcgcatct tctataacgt ctggtttact tttgtctgat tcagcaatag
     4021 tcgtccaata tttgagtgct gacattagaa ttggatttat acgaatgcta tctgctgttc
     4081 ttacactact tccttgatct tttatgactt tacttatatt tttcttggtt aattcgattt
     4141 cttctacttc ttttggtttg tagttctttt tatttttatt tcctagtagt ctacttactg
     4201 cagcttgact gcgattatct tctgccatca aaatcaccaa cttcttttaa atattcttct
     4261 gtaaatgctt tatagtcatc ttcagctgtt gagggtttat taaaattgat tagatctgat
     4321 ccagcagctt gcgcttcgtc aacggttatt gttctacgaa tataagtttt gaaaattttt
     4381 gcaccaatga ctctagaaat ttcggttgct gcagtcgtca tttctttaga aatgttataa
     4441 cgcttattat acttagtaaa taggactcct cgtacttcaa gcttgtcgtt cgtatattct
     4501 tttaccgttt caatagtttc acttaacttt attagtcctt ttaatgagaa atacgcagct
     4561 tcaactggaa tgataatttc atcagaaaca gtaaatgcgt tgactgtaag cattcctaaa
     4621 cttggtggac aatcaattat aatataatca tagttgtcct tgattggttg aagtactctt
     4681 ttaagcctgt gttcacttcc tacttgagta aattccctct ctgcagaaga aagggctatg
     4741 tcggctggca aaacatcaat tcctttatag tccagaatag catctgtaat gtcagcctcc
     4801 ccttttaata cttcataaat tgtaggttgg tttgttccat ctatatcgaa acctacatta
     4861 tctgtagcat ttccctgagg atcaatgtcc actaaaagta catttttacc gtaaacaaat
     4921 ttcaaacatg ctgctaaatt aacgctagtc gtagttttag aaactccacc tttttgattg
     4981 gctactgaca atattcttgc cattaaaata tcccccattc atcttatatt ataatataat
     5041 tatatcataa tattgtgata ttgcaatatc gtatatgcat tatattgtaa tattgtgtga
     5101 ttattttgtt ttaaagatat atatcggttc ggatataaag attattcata tgttattcga
     5161 aagtaaaata atcacttttt attactttaa aattttttat taatcataag aaatatgttt
     5221 tgcgaggaga gtgtaaaata ttttgtgtaa atgaaaaaat ccatacaaaa aaggaagtcg
     5281 cttctgtaga ataaagttaa cgacaaccaa ttcacagaaa agaggacttc cctatgaatg
     5341 attttactac agaaattgtg caaactctag tcactaaagg cgatttaaat gaattattcc
     5401 gttcgcactt agaaaaagcg ataaacacac tcctacggac tgaattaacg gcttttttag
     5461 attacgaaaa atatgatcgc actggtttta attcaggtaa ttcgagaaac ggttcttact
     5521 ttcgatcaat caaaaccgaa tatggtgaat taacattgga aatacctaga gatcgtaatg
     5581 gtgagtttaa acaacaaact ttaccagcct acaaaagaac aaacgataca ttggaaacca
     5641 ctattatcca tttattcgaa aaaggtgtta cgatgtctga aattgctgat ttgatcgaaa
     5701 aaatgtacgg tcatcactat actccacaaa ccatgtccaa catgactaaa gttctgactg
     5761 aagaagtaaa tgcctttaaa tccagagcct taaatgataa gtatgtcgct atttttatgg
     5821 acgctactta cattccacta aaacgtcaaa c
//
LOCUS       DAZULR010000097         5809 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.102, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000097 DAZULR010000000
VERSION     DAZULR010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5809
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.102"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            450..1604
                     /locus_tag="ACG8ZV_002674"
     CDS             450..1604
                     /locus_tag="ACG8ZV_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C47 family peptidase"
                     /protein_id="HFS4997928.1"
                     /translation="MIILKPKNKIYLGLLFSLMIGIFSIGITNTYASENSNFNINSQP
                     IEEQAINFAKTDFEHSITSILLMENNTETDINYTLGSPFKMLDGENTANSSIFFPVFS
                     DADNTIKYVYTVKKNTNGEYSGSISQFLAKELQNLVDSNITDTTLFFQDNSIYYSDNG
                     QIKLLWKSPLSTEKNGVSSFTEKNDLISVNIKNKIKNFSKKQNFPAVKRVKSVSSGDN
                     FIMINWRIAETQTSFPWCAAYVEAAILCNKTDVRATSARAIMHYTYPNLNNSQIESKS
                     LNQDQIIKYANYCGVYPKKVARILNLSEVQTQLRKGNAIYMGTAGYGNYSNSRHALAL
                     FGWVNQGGYQTYYVWNPWYNYPTVISANAGPVTIPVPGGGFTWDNTITNW"
     gene            1577..2020
                     /locus_tag="ACG8ZV_002675"
     CDS             1577..2020
                     /locus_tag="ACG8ZV_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997929.1"
                     /translation="MGQYHYKLVNKPIVLVMGLVLVLFLTSCSKKQEIQKTELIPFLG
                     TWQTKDHSERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNL
                     LTLRSNKKQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
     gene            3143..4075
                     /locus_tag="ACG8ZV_002676"
     CDS             3143..4075
                     /locus_tag="ACG8ZV_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFS4997930.1"
                     /translation="MANEIVKYKPELNTIPLRKFTPIEMNLFFSIVSRMRDKGNQKIR
                     FYFDQLKDLSAYKQTAGEVFIKDLTRTYDHLMDLRFGKKSNGGLTIERFTMFTDFEIH
                     GEADNPYVDIKVHEKALPLLNNLESWVRFSLTEFRDLNSSYAKTMFRLLKQYRTQGWA
                     EFSKEDFLELLDIPKSYRQTNINQFVLKPIKEELTPLFKGLTIRKKYGKGRGKPVIGY
                     RFTWKAEINHADDFSKGKQEDLRTKLFNIEHNGELTQEEKWRAKDRILDLPLGTHEAN
                     FKKQQQTEKEEVEKQTLSNELKQDLLGNLQNLFD"
     gene            4092..4607
                     /locus_tag="ACG8ZV_002677"
     CDS             4092..4607
                     /locus_tag="ACG8ZV_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HFS4997931.1"
                     /translation="MADKTIKDLAEELGVSKTAINKKVSDENRKLWFAKIGNKFVINE
                     IGQKAIKSMFFTENENSNQQPVGEKSKTENHKNANQVSELELFFFLEKQLNQKDIQLQ
                     EKDEQLKQMQKLLDQQQQLTLQANQQIKKLHEQLQLTYAEESSEKEPLSVTEETQKGQ
                     NKEKKWWQFWQ"
     gene            4903..5184
                     /locus_tag="ACG8ZV_002678"
     CDS             4903..5184
                     /locus_tag="ACG8ZV_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000353845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997932.1"
                     /translation="MDILVRNINPKIITRVDKRCQELTTKTGEKWSRNKYLKVLIESD
                     FDRQLMNYKKEQFDLLLEKFIDIQTKNTETLNDYVHTNNQLIETLIGGI"
     gene            5186..5602
                     /locus_tag="ACG8ZV_002679"
     CDS             5186..5602
                     /locus_tag="ACG8ZV_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997933.1"
                     /translation="MRKTSVQKHVTLYPSHIDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EKQLNPSQRNQPKNRQKETSQTFTSKNFDPTNFLKR"
BASE COUNT         2228 a          961 c          930 g         1690 t
ORIGIN      
        1 aaaaaaaaag actgctcgaa agagcagtct caagcaaaaa ataaacgaac aaacgcaatt
       61 actcacgaac acaaacaaat acaataaaat acctaaataa tgaaaataag tgataaaaaa
      121 caagggtatt tatagtttaa caagcgctca taaaaataac aagtctttaa aaaatgacag
      181 ataaaaatgc acaaagaatc ggacacagat aaccgcgaaa aatcaagctt tagaaagttg
      241 tttttagcta gaccaatgaa aaatcacaaa gtccgcccct gtatccgttg gtagaggggc
      301 tacttggttt agtatacatt atgttaacta gctcgttaaa taacgattat gttcccaaaa
      361 caatatttta tgaactataa caaaaatttg ttatcgcata ttgtatattt taattatagg
      421 tgtatatcac ttaattttaa cacaaaggcg tgattatttt gaaacccaaa aataaaattt
      481 atctaggtct cctcttttcc ttgatgattg gaatttttag tataggaatt acaaatacct
      541 atgcttcaga aaattctaat ttcaatatca actcccaacc aattgaagaa caagcaatta
      601 attttgcgaa aactgatttt gaacactcca taacttcaat tcttttaatg gaaaataaca
      661 ctgaaactga tattaactat actcttggtt cgccatttaa aatgctcgat ggagaaaata
      721 cggcaaatag ttctattttc tttccagtat tttcagacgc tgataatacg attaaatatg
      781 tttataccgt caaaaaaaat acaaatggag aatattcagg aagtatttca caatttttag
      841 caaaagaact tcaaaatcta gtagatagca atataacaga tacaacctta ttttttcaag
      901 ataatagcat ttattattcc gataatggcc aaattaaact actttggaaa tcacctttaa
      961 gtacagaaaa aaatggtgtc tcttccttta cagaaaaaaa tgatcttata tccgtaaata
     1021 taaaaaataa aattaaaaat ttctctaaaa aacaaaattt tcctgcggtt aaacgtgtaa
     1081 aaagtgtctc ctccggagat aactttatta tgattaattg gcgtatagca gaaacccaaa
     1141 caagttttcc gtggtgcgct gcttacgtag aagctgctat cttatgtaat aaaacagatg
     1201 tacgcgctac ttcagctaga gccattatgc attataccta tcctaattta aacaacagtc
     1261 aaattgaatc aaaaagtctt aatcaagatc aaataataaa atatgcaaat tactgtggtg
     1321 tttatcctaa aaaagtagca cgaatactaa acctttcaga ggtccaaaca caactaagaa
     1381 aaggaaatgc catttatatg ggaactgctg gttatggaaa ttatagtaac agccgtcatg
     1441 cacttgcatt atttgggtgg gtcaatcaag gtggttatca aacttactat gtgtggaatc
     1501 cttggtataa ctacccaact gtaataagtg caaatgcagg gccagttaca attcctgtac
     1561 ctggaggtgg ttttacttgg gacaatacca ttacaaattg gtaaataaac ccattgtttt
     1621 agttatgggt ctagtgttag ttcttttctt aactagttgt tcaaaaaaac aagaaataca
     1681 aaagactgag ctgattcctt ttctaggaac ttggcaaact aaagatcact cagaacgtct
     1741 agtaatcact aatttaaata cttcaaaaaa tatagaacaa tataccatct tagtaaaaga
     1801 gaacaatcat aaaattcaaa tcattgataa aaatttaaat ataaatgaac aagttttcat
     1861 ttacaaagca acaaataatt tactaacact gcgctctaat aaaaaacaat tagattacac
     1921 ttttagtttg gattctccaa aaaagctcgt atttattttg acaacgaatg atgggacaga
     1981 agggacagct aaaccaattg aattttttaa agctgattga tgaatagttg tttgatatta
     2041 caaaacaata atttcaccga aggtgaaaca agcgaaactt tacaaaaagt ggctagcatt
     2101 tgctagcctt ttttgtattg cggagcgtga gttttgaggg ggattcaagg gggagtttct
     2161 cccctttgac aagcggttat ttgcaccaaa tacgaaggta tttggctagc aaatatagag
     2221 cttgccaaac cctttagtgt gttttgtaga aagggacctt atagtcactt tcacattaca
     2281 aacgatacgt cctatggacg tatcaaaagg gtgggactta tgagcaaatt aaagcaaaat
     2341 ttggctagca atccttctaa aaaatacacc tattgatcag agtcaaaata aatcagtttt
     2401 cgagtgagcg aatccgaatt tgcaaatctg aagctttgca aatgagtgtg ccggcttccg
     2461 taaaagtcta ggtaacatta gtcgatatat acataaggct ctaatttgcg ttttaaggcg
     2521 ttttaaacgt tctggtatgt aatttatacc aaagcgactt taaaacgcct taaaacgaat
     2581 tttataggtc ttgtaggacg tttcagggtt gttagggctt gccctgaccg cctgtaaggc
     2641 gctttaaaaa caagataagg gattttatct agacttgtct taaaacgccg tagatgagcg
     2701 ctcagagctt cttaaaggac tccttacgaa ctgtttttaa gcaaaggagc ctttaggcga
     2761 ctgcgcagtt caatgtgaga gcgtagcgat cacaccttta aagcgaccgt agggagcaga
     2821 ttcccagttt aggaaatttc gcgaacctgt ttggagaaaa aaagtaggaa atttttaggc
     2881 gggaaatttt gcccccctct tttataatct cttttataac ctctttttaa acctctttac
     2941 cgtcggctgt atccttactc tcccaaggcc tgtagctttt ttagggcatg aaattatctg
     3001 tttataggca tgaaattatc tgtttatagg catgaaatta tctgtttata ggcatgaaat
     3061 tatctgtttt aggtattgtt ttaagacata atatacctta aaattatgtc aataaaatta
     3121 gttagactgg agtatcaaat aaatggcaaa tgaaatcgta aaatataaac cagaattaaa
     3181 taccattcct ttaaggaaat ttactccaat agaaatgaac ttgttttttt ctattgtttc
     3241 tagaatgcgt gataaaggta atcaaaaaat acgcttttat ttcgatcagc ttaaagattt
     3301 aagtgcttat aagcaaactg ctggagaagt ctttataaaa gatttaacaa gaacatacga
     3361 tcatttaatg gatttacgtt ttggaaaaaa aagcaatggt ggattaacca tagaacgatt
     3421 tacaatgttt actgattttg aaattcatgg agaagccgat aacccttatg tggatataaa
     3481 agttcacgaa aaagctttgc ctttacttaa caatttagaa agttgggtac gtttctcttt
     3541 aacagaattt cgagatttaa atagcagtta tgctaaaaca atgtttagat tactaaaaca
     3601 ataccgaaca caaggatggg ctgaattttc caaggaagat tttttagaac tattagatat
     3661 tcctaaaagc tatagacaaa caaatataaa tcagtttgta ctcaaaccca taaaagaaga
     3721 actcacacca ttatttaaag gattaacgat tcgtaaaaaa tatggtaaag gccgaggcaa
     3781 acctgttatt ggttatcgtt ttacttggaa agctgaaatt aatcatgctg acgatttttc
     3841 aaaagggaag caagaagatt tacgtacaaa attatttaat attgaacaca atggagaatt
     3901 aacgcaagaa gaaaaatggc gcgctaaaga tcgaatacta gatcttccgt taggtactca
     3961 tgaagctaat tttaaaaaac aacaacaaac tgaaaaagaa gaagtggaaa aacaaacact
     4021 ttcaaacgaa cttaaacaag atttattagg aaatttacaa aacttattcg attaaagtat
     4081 aaggagtatt tatggcagat aaaacgatca aagaccttgc tgaagaatta ggagttagta
     4141 agacagctat taacaaaaaa gtttctgacg aaaatcgaaa actttggttt gcgaaaatcg
     4201 gaaacaagtt tgtgattaac gaaatcggtc aaaaagctat aaaatcaatg ttttttaccg
     4261 aaaacgaaaa ctcaaatcaa caaccagttg gcgaaaaatc gaaaaccgaa aaccataaaa
     4321 acgccaacca agtttccgaa ttagaactct tttttttcct agaaaaacaa ttaaatcaaa
     4381 aagatataca gctacaagaa aaagacgaac aattaaaaca aatgcaaaaa ttactcgacc
     4441 agcaacaaca actcacctta caagccaatc aacaaatcaa aaaacttcac gaacaactcc
     4501 agctaaccta tgcagaagaa tcttcagaaa aagaacccct ttctgttact gaagaaactc
     4561 aaaaaggaca aaacaaggag aaaaaatggt ggcaattctg gcaataaccc aacaattttt
     4621 attcataaaa attgttgggt tactttcttt ttttgctttt acaagcatag cgacatgatc
     4681 tcacgtcgct attttttaaa gagcataagg aaacgcggta tcactttctt acgaaaggtg
     4741 ctaggtaggc tgtgcctacc acgtttctaa gaaaaaaatt tgctatcact ttttcgccat
     4801 tgtggctagc ttatgtatag tatttcggta aaaaacagct atacaaatac tatatttgta
     4861 tgatatacat aaattataca cacataagaa aggacgtttt ctatggacat tttagttcga
     4921 aatatcaatc caaaaattat tacaagagta gataaacgtt gtcaggaact tacaaccaaa
     4981 acaggagaaa aatggagtcg aaataaatat ttaaaagtgc taatcgaaag tgattttgac
     5041 cgtcaactta tgaattacaa aaaagagcaa ttcgatttat tactcgaaaa atttatcgat
     5101 attcaaacaa aaaatactga aacattgaac gactatgttc atacaaacaa ccaactcatt
     5161 gaaacactta tcggaggaat ataacatgag aaaaacttct gttcaaaaac acgttaccct
     5221 ttatcccagt cacattgacg ttttagattc catcatcgaa aaaaatccag atatcaataa
     5281 ctactcggaa gccattcgct ttttatgtat gagttatgaa cctgatacca atacaacaac
     5341 taccagtaac caagccaaac taaatgcgat gggaaaagaa atttctatca tgaccgaaat
     5401 tatcgcagaa tttgctgatt tgtatttaaa agatacaggc gttcttatcg gtacaaactc
     5461 gaaagtatat caagaagtaa aagaaaaaat tgaaaaacag ctaaatccct cccaacgaaa
     5521 tcaaccaaag aatcgtcaaa aagaaacgag tcaaacattc acttctaaaa atttcgaccc
     5581 aaccaacttt ctaaaaagat aaaaaaataa accaggaaat ttttaatttc ctggtttatt
     5641 ttctagagag cggtcttcca ataagatttg caaatcgatc ccaatttgcg taaaaaaaaa
     5701 gctgctcgta cgagcagcta aacaagaaaa agtcagcttg ttttaagggt aaaataagtg
     5761 taacaaattt tgcgaatgca acgatctttt ttattatacg caaacaatc
//
LOCUS       DAZULR010000098         5727 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.103, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000098 DAZULR010000000
VERSION     DAZULR010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5727)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5727)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5727
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.103"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            196..921
                     /locus_tag="ACG8ZV_002680"
     CDS             196..921
                     /locus_tag="ACG8ZV_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997934.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHSQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWRLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            911..1420
                     /locus_tag="ACG8ZV_002681"
     CDS             911..1420
                     /locus_tag="ACG8ZV_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997935.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(1490..2938)
                     /locus_tag="ACG8ZV_002682"
     CDS             complement(1490..2938)
                     /locus_tag="ACG8ZV_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFS4997936.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(2938..3654)
                     /locus_tag="ACG8ZV_002683"
     CDS             complement(2938..3654)
                     /locus_tag="ACG8ZV_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HFS4997937.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAAVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            complement(3635..3985)
                     /locus_tag="ACG8ZV_002684"
     CDS             complement(3635..3985)
                     /locus_tag="ACG8ZV_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HFS4997938.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            4129..4902
                     /locus_tag="ACG8ZV_002685"
     CDS             4129..4902
                     /locus_tag="ACG8ZV_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFS4997939.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMDNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            5073..5439
                     /gene="ssrA"
                     /locus_tag="ACG8ZV_002686"
     tmRNA           5073..5439
                     /gene="ssrA"
                     /locus_tag="ACG8ZV_002686"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
BASE COUNT         1662 a         1124 c          994 g         1947 t
ORIGIN      
        1 aaaattattg tcgctgctcc tcttttcgaa taaacagtgt tcaaaagctt gcatctacgg
       61 taatagaata gggcagcttc ttcacaacct cttgcttttt acaaaatatt ttctggtttt
      121 aattcgtgat ttcactaaag gaatttcata ctttattcat attcattttc tatacttttt
      181 atagaggtga aaagtatgaa aataatccgc tatgctactg ctcgattaat ttattacaaa
      241 aagcagacaa tactctattg tttattttca agcttttctg cttttttatt gatagcatgc
      301 ctgactcttt accattcgca atcggcttta gccaatcaag tccaagatcg gctttcattt
      361 attggcgctt ctgcatctac agagcttctt ccggctttag aattagctag ccgattttat
      421 ataaaaggca tattcagttt attttttcta tttgccttcc tttttatctt tttcttttac
      481 tattcagtca ggcaaaacaa gcaggaattg atcaattggc gcctgactgg tctttctaaa
      541 accaaattat tcctttttat tttctggcag ctgttctttc ctctctttct ttgttgtatc
      601 ttggttttat tgtggatcgt cagcttccag tcagtttatg aagcgcttct tcaaaggatc
      661 aattttcttg tcttaaagac tactgaactg ccagatatcc gtgatatctt gacttcggta
      721 agcggactta caattccgat ggatcaacag acttttttta ccatcgattt ccaaaatgat
      781 ctttttttca cagatatact taagggattt gcccaaactc ttattgggct cagtggatgc
      841 tgtctcattc ttagtctatt ccctttcact ttttttatcc atcatttgca aagtaggagg
      901 cctggacgta atgaaacctg aatatttgat tcatgctgaa cacttgaccg ttattttgtg
      961 tcctctcgaa aaacagcata aaatattgga gcacttgaaa aaagaggttc ttgttgcaaa
     1021 actggataat tttgcgatca tccaaaaaaa ttggccgatg tttccttatc tgaatcttaa
     1081 agaccatgtc ctgttggatg taccggaaaa agaaatcaaa caagatcgtt tggcctatca
     1141 agaaaaactt gatatctctc cttccttgct taattgtgcg gcagctgagt tgacgtcttt
     1201 tgaaaaagta aagctgcaat tacttcatgc cttgctttcc aagcgaaaca atattgttat
     1261 tgaagataca tttgatgaac ttagtgtatt ggagatccaa gagctactcc acttgctttc
     1321 ttatttagct catgaagaaa atcaaggtat cttactcttt actcatgatg ctactattgc
     1381 tcaaagtcct tatattgatc gtttagagcc cgcgggctaa atcaatcatt ttatagtaaa
     1441 aacaagcggt atagaagatc gattcatgat cttttatacc gcttgttttt tactcttttt
     1501 tgatttctac gtcaggcaaa cgaacagcga attttgttcc ttttcctagt tcgctttcta
     1561 cttctaattt tcctttatgc aagcgtacaa gttgctgcac gattggtaaa cctaatcctg
     1621 attcaccata ttttgtattt tttcttgaag gatctacttt ataataacga tcccagatac
     1681 ttttcatttg ttgttcagac attccaattc ccgtatcttc aatcgtgatg atcgtttcaa
     1741 gatagccttt ttctaaagta atcgtgattt ggccgttttc agtaaactgt atcgcgtttt
     1801 gaataatatt gaccatgatt tggacaaatc ggtcataatc agcgtaaaca tcaatatcat
     1861 caacggcttt caatgtcaat gtatctcctg ctgcttctgc tttagcttct aactgtgcaa
     1921 caatattttt caatgtttct gttccattga attttttaat gaccatactg atttgattcg
     1981 tacggatttt ttcataatcc aagttttcat tcaccaaacg gatcagacgc tctgtttcat
     2041 ttttcatcaa tttaatcgcg ttttctcgct gattttcagg gattgcattg tattctaacc
     2101 cttccagaag tccgttgatt gtcgtaagag gtgttctcat ctcgtgagaa gcatctgcca
     2161 taaattgtct tcgacgattt tcttgttctt caatttctgc ttgagattct ttcaatgaat
     2221 tcgtcatttt attgaaatca tctgctaact catcaaattc atctttgtca tgtacgggga
     2281 gctgtacatc aaaattacca ttcgtcactt ctttcgtcgc attccttaac cgattgatac
     2341 gcttaacttg gaatgctgca aaagcatagc tggcaataac tgcaacgata ctggaaaaaa
     2401 taaatccttt gaacaggttc agtgtaattg gacgaacgct gttatcgata tttcgcgcag
     2461 gttgactaac tacaagtgct ccatagaatt catgattcaa attaaatggc acaagtgcgt
     2521 aagaggtcgc ctgtgcttgt cctaaaatat ttttattcga tgtgaatttt tcttgacgtc
     2581 cattcctcag atttttccat tgatcagctg ttaaggtaaa attcagtaaa gctgtattag
     2641 tcggataaat gacacgttcg tttttatcga taaatataaa gttcacattt tgttctgtca
     2701 gtacttgctc tgtcagcagc aatgcatttt gaaacgcctg atcttgacta aactgcggga
     2761 gcgtatcggc ataggtttgc gttgtctttt caactgattc agcatatcca aacagttgct
     2821 ggtaattgtt ttcttcaatc gtttgttttg tcagttgtgt aaaagaaact ccaacgatca
     2881 ataagatcaa cgcgaccatt ccgcaaaaag ctaagagttg ctgatacaaa taacgcatta
     2941 ggcaacacca gaatcatcga atttgtagcc gactccccaa acagtttgga tgacttgtgg
     3001 tccgaccttt tcgatttttt gtcgtaattt cttgatatgg gcgtccactg tccgttcatc
     3061 accaaagtac tgataatccc agactaattc aagcaactgc tcccgagaga atacttgacg
     3121 tggttttttt gctaaagtaa acaatagatc gaactcttta ggcgtcagtc cttcaattgg
     3181 ccggttgtcc agatacgctt ctcgtgtttt cgtattcatc ttgaaatgac tagtctcgat
     3241 atcaaaatga tcatctgaaa ctgctgcttc ttctcttgct tctgccaact cactacggcg
     3301 atgcaaagct ttcattcgag caataagcgt cagaggactg aaaggttttg tgacataatc
     3361 atctgccccc atctctaagc cgatcacctg atcgctttca gaatctctag ctgtcagcat
     3421 gataatcggc acagtacttg aaactttgcg gatctctctt cctactagca taccgtccag
     3481 tgtgggcaaa ttcaggtcta gtgtaatcat atcccaatgt tgtgggtttt ctaaaaaggc
     3541 atcgagccct tcttttccat catacttgaa agttgcttcc caaccttcat ttaagaaaaa
     3601 catctgcatc atttcagaaa cagattgatt atcttcaatc attaaaatat tcattatcgt
     3661 tccctccagt ttccaggtca tatttctgta atttcttttc tgtcataata aaaataggca
     3721 taattggaaa tactagcaga agcatttcaa tcagaaaata attcgtatgc ccagatgtct
     3781 ttaaataata gccgatcaat gccatcagta agcccataag aaaaaaccag tttccgcttg
     3841 tcttttgagc cagccgccaa tgagcgtctg tttttgcggc aagaggcgaa tgatacccat
     3901 aaaaaggcag atttcctttt gagggcagaa tccgaaaaag actgccaatt attaagaata
     3961 agataccaat actgaaaaaa atcattcttt ccctcctaaa ttctcttctt atagtatact
     4021 ctaaattgtt gactgaacca atatgttcag gaattcttca cgaaaggttt gtcttttgtt
     4081 cattctttgt taagataaac ttattccaat aaaaaaggag ttttatttgt gtcaaattat
     4141 cgtgcaatca ctttctttga tcttgatgga acattactag atgcgaaatc aaaaatcaca
     4201 cccgaagtgg caaaagctat gaacgcatta aaagaaaaca atgttctccc cgtcatcgct
     4261 acaggacgta cagaagcaga aatccactct atcatggaag atgcgggcat tacttctgcg
     4321 gtcaccatga atggttcttt cattcgagta gacggcgaag aaatctattc tcaaacattt
     4381 tcttcagaag aatgtcaaaa aatgtatgat catgtacagt tgaacggtca tgaactttct
     4441 tactataacg atcagaaaat ctggtgtacc ggtcatagcc aaacaatgat caatgcttac
     4501 gacttcattc attcagatgt tccggaaatt gatcctttag gctttaaaga aaacacagta
     4561 aatatgttgc tgatcttatc tcaatcaggt gacgaatact atcacgaaca ttttcctgag
     4621 ctaacttttt atcggaatgg tccttactcg atcgatacag tgaagaaagg aatctcaaaa
     4681 ggggcaggtg tcaaacgtct gcaaaaagaa cttcagctgg aaaaagttcc tacttttgga
     4741 tttggcgatg gtccgaatga ttttgccttg ttggaagctt gcgacaacaa aatcgctatg
     4801 gacaacgcct atgacggatt aaaagaactt tctaccttta tcacaaagaa aaatacagaa
     4861 ggcggaattg tccacgcatt gaagtatttt gatctgattt aagatctttt tttgaagcta
     4921 cctcttttct taagaaaatc gcttattttt tcttaagaaa ggggcagtta ttatataaat
     4981 aatgggatat gattcgcttt tttattgaat ttatcccaat atatgctata ctaattttgt
     5041 atgaaaaata cacgtaaccc ttgttagcta acggggacgt tacggattcg acaggcacag
     5101 tcgagcttga attgcgtttc gtaggttacg tctacgtaaa aacgttacag ttaaatataa
     5161 ctgctaaaaa cgaaaacaac tcttacgctt tagctgccta aaaacagtta gcgtagatcc
     5221 tctcggcatc gcccatgtgc tcgagtaagg gtcctaactt tagtgggata cgtttcaact
     5281 ttccgtctgt aagttgaaaa agagaacatc agactagcga tacagaatgc ctgtcactcg
     5341 gcaagctgta aagtgaatcc ttaaatgagt tgactatgaa cgtagatttt taagtggcga
     5401 tgtgtttgga cgcgggttcg actcccgccg tctccatata tgtatggttg agacagataa
     5461 acatgtatga aaaacgttgt taaatcaacg tttttttatt ttggtcaagg agagaaaagt
     5521 agagaaatac aaaatttttt gcattgattt tgcattcaaa aaaacattca aacatttaga
     5581 aatccccaat acgtattcag gaaaatctat tttaaggttt acaaaaagaa cttttgttcg
     5641 tacactcttt ttgaggtgaa cttttatgct gatggaagga aaaacacaat tatggtttaa
     5701 gcatgttcct tcaaataagt tttttta
//
LOCUS       DAZULR010000099         5691 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.104, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000099 DAZULR010000000
VERSION     DAZULR010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5691
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.104"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            58..510
                     /locus_tag="ACG8ZV_002687"
     CDS             58..510
                     /locus_tag="ACG8ZV_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997940.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            524..1213
                     /locus_tag="ACG8ZV_002688"
     CDS             524..1213
                     /locus_tag="ACG8ZV_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997941.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1338..3689
                     /locus_tag="ACG8ZV_002689"
     CDS             1338..3689
                     /locus_tag="ACG8ZV_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase domain-containing protein"
                     /protein_id="HFS4997942.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3769..4164
                     /locus_tag="ACG8ZV_002690"
     CDS             3769..4164
                     /locus_tag="ACG8ZV_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997943.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            4489..5106
                     /locus_tag="ACG8ZV_002691"
     CDS             4489..5106
                     /locus_tag="ACG8ZV_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFS4997944.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            5147..5446
                     /locus_tag="ACG8ZV_002692"
     CDS             5147..5446
                     /locus_tag="ACG8ZV_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HFS4997945.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            5480..5647
                     /locus_tag="ACG8ZV_002693"
     CDS             5480..5647
                     /locus_tag="ACG8ZV_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFS4997946.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
BASE COUNT         1996 a          751 c         1161 g         1783 t
ORIGIN      
        1 caattatctt atcgtagata tatattataa atttaataag aaagcgaggt gagaatcgtg
       61 aaaaaaacga tactaagtat tttttcagta tttacaatat taattggggg ctattttctt
      121 ttgaatttag attctgttaa ttcaaacgct caaataaaag atcaaagagt agctgaacat
      181 aataataaaa aaatgagttt gaccaaaaat atctattcta tgtcagatga agaattgtat
      241 aaagaatttg gtgatttatc cggggaacag ttagaagaaa gtattccagg aattagtgac
      301 tcagataaaa ttgttgtctt gtctgctggt gggcaattaa tgggagatgg caaatccgaa
      361 ttagttagtt ataaacaaaa tcacagacag tttattgatg ttaatactga ttccaacgct
      421 atttcgatta aggatctaaa agagctttta aatagtaaaa gaaatgaatt aaagcagata
      481 aaagaaacta attcagtgga attagagtaa aggaagattc attatgaaaa agatttttgg
      541 tgtttctgtt gggctactta tgatgttaac atttggaaat gcagtatatg ctgctgagaa
      601 agaagttatt tcagatccag agcagtacgc ctcacgatac tttgctgatt ttgaagaaga
      661 agataaagta cttgcattgc cagaaggtgg ttttttaaaa ggggaagcta aaattgtatc
      721 tatggataat ccagatataa ttcaaggttc atataattca gaaactgatc ctgcttcagt
      781 ttcagtgaca gaagcaaaaa aaattgttgc tgaaaaattc aaaaatgata ttgaaactac
      841 tccaattatg cctcgaggag catttccacc cgatgttggt actagcggac accttcttgt
      901 actagcagga ggaggaagct ataaatcaca gccatttagt ggtgcgggat ggcgttttgg
      961 aggtatgggt gtaaaaccag ctgatggtac aggcaacttt ttacgttgga aatcctacat
     1021 tgacgatgga agagtaggaa atgtaaatca agccaacgca actaaatctg gttctattca
     1081 aggaatggca ttgtatgctc gtgaaggatt caaatacttt gcaccaaacg ggcctggttg
     1141 gacaatgaat ataggtattt attacactta taatcctgtt gcaggtacgt attatgttgt
     1201 tcaaaatatt taataaaaca gcacaaagag atttctttgt gctgttttat tatttttagt
     1261 tgttgacaaa cactaaaata taaaatataa tcaacacata aacgaacgta tgttcggcaa
     1321 gaaagcaggg gatttttatg gatgagatgg ttttaagtac tcagaaatgg ctaaacaaga
     1381 aatacagtaa tgttacaggg tttgataagg ttccagaaaa tgggcgaaca gggtggccta
     1441 caatctatgg acttattgaa ggactacaag tagaacttgg tattactaat ctagtagcta
     1501 attttggacc taccactgaa aaaatgtacg ataatcaggt tactcctaaa tggggcaaaa
     1561 atctacctaa aaatattgta tttcttattc aaggtgcctt ttggtgtaag gggattaatc
     1621 caggtggctt cgatggggta tatactccat atttagatac tgctgtaaaa gagttgcaga
     1681 ctgatgcagg gtttaatgga agcgctgtaa ctggagtttt ggatgcgaaa tgggccaaag
     1741 cgttatttga tatgagtgct tttgttcttg ttcccggcgg agatagtaaa attagaaaaa
     1801 tgcagcaatg gttaaatgta aattatttag aatacacggg aataatgcct tgtgatggta
     1861 tttatcaaag aaattcaaat caagcattaa tttttgcatt acaagctgaa ctaggatatt
     1921 ctcccagtga agcaacaggg tcttatggta atgggacaac tagtaaaact tatcctgtgt
     1981 ctgaaggtaa ctcgggaaac tatgtaagaa taattcaata tggattatat gttaatggtt
     2041 attttgaaga cggtacattc gatggtattt tcactaaata tatgggttta gaagtactgg
     2101 cattccgaaa atttatggta ttgcctgaat atactgaaat agcagatgtt gttgtaataa
     2161 aaggactatt gtctagcgct ggagatatta gaagatctgc agatggcgca gatacttcta
     2221 cgcaattaac tagatctcaa atccaaacat tggttgataa tgatataaaa atagttggta
     2281 gatatcttac tggtactgtt ggaattggaa aagatgaacg aaataagtat ctaactacag
     2341 aggaattgaa taatattttt tctaaaaatt tatctgtgtt tcctatctat caagatggag
     2401 gtgcagcatt agcttatttt acttatgatc gtggcttatc agatggtaag aaggctatag
     2461 atgcagcaaa aaatctaaat ataccattaa caacagttat ttattttgct gttgatctag
     2521 acatgttagg ggaagaaatt cttgcatatg ctggagaata ttttaagggg gtatctgctg
     2581 taatgtcata tagcgggtat caaacgggtg tttacggaac aagaaatgtt tgttctcaaa
     2641 taatcaataa cgggtatgct tcgtttgcat ttgtttcaga tatgtcgact ggttatagtg
     2701 ggaatttagg ttttcctatg cctagacaat ggtcttttga tcaatttgtt gaatttacca
     2761 taggaagtgg caacggagct gttggtatcg atttaatcgc tacatcgggt agagatagcg
     2821 gatttaatga gttatcaaat gatactaata atgataatta cattgccaaa tacaatcaga
     2881 aggttataaa tcagatggta cgtgcgtatc aatatctatc acaagctggt cttgataatc
     2941 cttggaaccc tcatttgaca ttttatagat atgtaaatta ttctggtttg tcatgggaca
     3001 tcatttcttc tcctgtaaca gagcatgata gaaaaattta tgatgaatat aggaataaat
     3061 taactaatag cgagggcctg tataattatt ttatagatcc taatactggt tcaataatag
     3121 gtttgcctca cttaattgtg acgttacaat cacagatgtt tctagccgac acaatcaatg
     3181 atagtgtttc tgactttgca ggttggttag gagatttaat gacttgctgg ggtgaagtta
     3241 agaaattagg aatacaaatg gagcaaggtg tatttgcatt agtaggtacg gctgcaggtg
     3301 gaacatttag tctagaagat ttataccaag atgttgacgc ggtaaatgtt tataccttag
     3361 caaaaagaaa ttctgattca acagctttat cggctttaaa aacgtactat tgtgataagg
     3421 gtgctattga tagatttaat caatttgtta agaacagatt tggttcttca gataaaatcg
     3481 cttcagtaac aaatagttta ttagaaaatg acgaaacagt tgatatctta ggtgtaggga
     3541 taatttcatt tttcattgat aaaatagtta ataattcact tgggacagat tttacttatc
     3601 ttgattttat tggagatgag gggaaagttg caaatggatt ttctgaaaaa attattcaat
     3661 ttcaagaaaa tagaagtaaa cttaattaag aatcgtttac tatttaaaca gtgtcctttt
     3721 cctttttaaa tatatacgat aaaataagta tatgaattgt aaaaggacat gatgattatg
     3781 gaagaaatag aatggaataa tctgactcaa aataataaaa ataattctgg atgtggaatt
     3841 atctttatgt ttgttatagt tttgggaata gtagtacttt taataactgt caagatagta
     3901 gattactttg cgaatactcc tgaagaacaa atacagagaa aacttcctga gtttgaaaga
     3961 gtaccacctt atgatccaag agataattca tttcaagtaa aaaaattaaa agagtctcca
     4021 aatgaaatgt ggtttgaagt tacagttgaa tcaagcgact tcaaagaaaa aaagaaagaa
     4081 tacaattata ttgtaaaggc aaaagtatca aaaagattta tttttaaccc taaattagaa
     4141 atatatagtg ttgtaataga ataatagtgt taaaaaaatt gtaaaagtta aagaagtcaa
     4201 attctgatgt gaaaaataaa atataccatg gaagacataa aagaaaaact ggataactag
     4261 tttatttaat ggcagaccgt taaggcctgc catttttatg tattttagcg gaataaatat
     4321 aatcatgcgg gagtgtaaac ttactgtttc aaaaagtata ctttttgaca tgccttgatt
     4381 ttctttgttt atgtatggca taataaccac ataatacaat ttgaaacgtt tctgatttaa
     4441 tctgattgtt ttgaaacaat tttagtgaaa aaagggtaga taaaaacgat gagaaaattt
     4501 ttttatatcc gggtcagtag ttatgatcaa tcgatcgaac gacaactgat ttccgcgaag
     4561 gaattaggaa tccctgaaga atatatattt gtagaaaaag ccagcggcaa agattttaaa
     4621 cgccctgaat atcaattaat gaaacggatg tttcgaaaag gagatttact ctatctacaa
     4681 tcattagata gactaggcag aaataaacaa atgattttag aagaatggcg agaattaact
     4741 aaggaaaagc agattgatat ttctgtgtta gacatgcctc tgttagatac tgctagttac
     4801 aagcaactag atgggttaga gacgcttatc tctgacttaa ttctgcaatt actcagctat
     4861 atggccgaag acgagcggaa acgaattaat agccggcaaa gagaaggcgt agaagctgcg
     4921 aaacaaaagg gtgtaaaatt cggcagaaag aaaattgctt tacctcctga atttcctgcg
     4981 atctattctg actggaaagc aggaaagata actgcagtct atgctatgga tcaattgggc
     5041 atgaaacgaa atacctttta tcgacgggtg aaagaatatg aacatacctt gcaccacttt
     5101 tcttgataga tataacagct attagacggg aagggagagt ttgaaaatgg acttaacgaa
     5161 tcaaagggtc gtttttactg gaacgctgca gcaaatgaca cgaacccaag ccatcggttt
     5221 ggttcactct ttaaacggcc attgtcaatc aagtgttact tcaaaaacaa atttcctggt
     5281 ttgtggtcag tattctaagt cgttgtttga tgattctctc tatacaaaaa aggaacaaac
     5341 cgcgcgggac ttgattgcgt taggtcatga gattaccatt ttatcagaag tcgaatttta
     5401 tgcgttaatt agtcaacagt tgaaagaatg gcaacggtat ttataatcgt tagtaaaatt
     5461 tacaaggagg aaaattttta tgaagcgaaa atcttatgat cgttggggca ttgaaataac
     5521 tagttttaat cgaaatattg cttttcacgt ggagtgtgac tgtggggaat tagcaaaaag
     5581 tgtttatcaa aaaaattact tttactgtcc taaatgccat cgccgatacg gggtacatgg
     5641 aacatagaaa cgaaatagtg cggtagaaaa gcgaatgaat gtagtatatt t
//
LOCUS       DAZULR010000100         5243 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.106, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000100 DAZULR010000000
VERSION     DAZULR010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5243)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5243)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5243
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.106"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(3..1151)
                     /gene="nagA"
                     /locus_tag="ACG8ZV_002694"
     CDS             complement(3..1151)
                     /gene="nagA"
                     /locus_tag="ACG8ZV_002694"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HFS4997947.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1227..2063)
                     /locus_tag="ACG8ZV_002695"
     CDS             complement(1227..2063)
                     /locus_tag="ACG8ZV_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4997948.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2247..3464)
                     /locus_tag="ACG8ZV_002696"
     CDS             complement(2247..3464)
                     /locus_tag="ACG8ZV_002696"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFS4997949.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(3613..3774)
                     /locus_tag="ACG8ZV_002697"
     CDS             complement(3613..3774)
                     /locus_tag="ACG8ZV_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997950.1"
                     /translation="MEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGIAMDWAA
                     NLWNDYHDN"
     gene            3847..3930
                     /locus_tag="ACG8ZV_002698"
     tRNA            3847..3930
                     /locus_tag="ACG8ZV_002698"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3881..3883,aa:Leu,seq:gag)
     gene            complement(4170..>5243)
                     /locus_tag="ACG8ZV_002699"
     CDS             complement(4170..>5243)
                     /locus_tag="ACG8ZV_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997951.1"
                     /translation="YVFEKINVKNLLLVCSIYCLIPLTVMGETGWRATTLNYQWPVAF
                     SLLTFYPFFQLLRGEEINRKIYWVSIPLLIFLTNQEQVNACFFVLTSIVSLYLIVNGR
                     YNYKLSVFSIISLAELIFSLTTPGNALRAAHEINKWFPEYKNFNFLNKLDLGISSFGK
                     PFFLDMNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYFGNTMGQSFTYVN
                     GNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLIVGIYLSFDNKKT
                     SIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMAVKELMKSMSVQK
                     NEFMQFGLTVLGICTFIITVINR"
BASE COUNT         1622 a         1073 c          832 g         1716 t
ORIGIN      
        1 tattatgcgt ggaaacgttc cacgccatct agataagttg cttccaatgt catatcaggg
       61 ttcaatacga taaagtctgc atcgcgtcct tgagcgattt ttccacatgt atcatcgatt
      121 ttacagctga ttgctggaat cagactagcc atcatgactg cttgttctgg tgttgctaat
      181 ccccagtcta caacattttt aattgcttct ttcaatttca atatacttcc agctaagttg
      241 ccagattcta gacgtgctgt tccttctttt actactactg gaaattcgcc taaattgtaa
      301 tttccatcag gcatcccacc ggccatcata cagtctgtaa ttaatgcgac atgatcatgt
      361 cctgcttttt ccattaggat tcccgcagca tttggatgta catgatggcc atcacaaatc
      421 aattcagaaa agacatgttc taaagataat aacgcaccca ccatacctgg ttcgcgatga
      481 ttcaatccac gcataccatt gaaagcatgg acaaatacac ttgcgcctgc ttcaacagct
      541 ttttgcgctt cttctagtgt agcattactg tgtcctagag aaacaactac tccttcttca
      601 gtcacttgtt tgacaaactc ttctacacct tgacgttccg gtgctaaagc aatttttttg
      661 attaaaccac ctgaagcttc ttgccattca tggaaagtat ccaaatcagg atccccgaaa
      721 taacttgggt tttgtgcccc tttgtgttct tctgtgaaga aaggaccttc aaaatagatt
      781 cctttgattt tagctcctgg tgcttcctga tacattttgc cgattgtctc agctacatct
      841 tttaaacgtt ctttgcttga cgtcaatgtt gttggtaaaa atgaagtcac tccacaagat
      901 aacagacctt cagacatcac tttgatgcct tctgcatcat tatccattac atcatgattc
      961 atatagccgt gaatatgtgt atctaccaaa ccaggagcaa tccatttgcc gctttggtca
     1021 atgatgttga cttctccctc aggtagttct ttggtgtatt caccaaaaag tccatcggta
     1081 atttcaagat agcctgcatg tttgacacct gacgctaaaa agaatttgtc agcatagata
     1141 aaagttctca ttctattctc tccctttgtt tttctacctc taaagtactc ttatttagag
     1201 aagaagtcaa gaatggtcta caccatttac aaattttttg aaatttgttt cacagcttgt
     1261 gctaagcctt catagaatgc tgctctttct ggttcttctt tacgcttgta tattaagctt
     1321 ttaagcacaa ataaatcatt gaggtaatag tagctattct tctcttgagc ccaatagatt
     1381 ccttgattca cctgttctaa cgcttcgtcg atttcatttt gatggaataa gaaatttcca
     1441 taattataaa aaatttgcga aaattcactt tttgatcgtt catcagctga ttgatgcagc
     1501 agttggatgc ttcgactcaa atagtagcgt gcttcagccg tttttcctgc cacaccatat
     1561 atttttccga tacaactaat cagttgtatt tctgtgtcag aaacatggat tctttctttt
     1621 tggctagagt agcttaatgc ttctttcaaa taataaaggg actgagagat attttgacgc
     1681 aacgtgaatt cgcaaacacc gagataataa taatagcgtt gaaagtcagt tgcttgatac
     1741 agattttcag aaatatcaga agattttagt acttgttcta acttccgata atcacgtttt
     1801 tggaaacaac tatccaacag ttcaaataat ttatcgtttg tccgagtagt ttttcgagag
     1861 agattcatca catgatcaat cgttacccct agccgttgac aaatctgcat catcaccaat
     1921 acattcggca gttcctcatt attttcgatc cgacttaata cactttgtga acaaatatca
     1981 tgcgaaagca ttttttgcgt cattttttgt tcttttcgaa tctctttaat gatcgttcca
     2041 aaggactcga ttaacgtttc cataagtatc ctccccaaaa tatgcgtatt cgcattctat
     2101 tcgtatttta ctttaggaag tcgcaaactt caagaaaaga cttgcaacta aataatatac
     2161 tttagttatt taagaaaact ccactagaaa gagagcctca gtgtgtttgt ctgtggccct
     2221 cctactgaaa aatttggttt ttaaaatcat ttttggcgat aggttgctag gaattctctc
     2281 attttcttag ctgtttgttt caaatcatcc attttaggaa gataaacgat tcgaaaatga
     2341 tctggctggt tccaattaaa tccaccacca tgtacaagta gaatatgatg ttcatgtaaa
     2401 aagtccaaaa cgaatttttc atcatccaaa atattgaatc gctttgtatc aatttttggg
     2461 aatatataaa aagcagcttt tggttttacg gctgaaagac caggaatatc attgattgca
     2521 ttatagatat attctctttg ttcatagatc cttccgcctg gcaggagcag ctcatcgaca
     2581 ctttgataac cgcctagcgc ggtttggata atttgctgag acaatacatt ggaacacaaa
     2641 cgcatggagg acaacatatt cagcccttct atatagcctt tgacgtgtga cttatctcca
     2701 cttaggacca tccagcctac tcgaaatcct gctacacgat gagatttgga tagaccgttc
     2761 agcgtaacaa cgaacaaatc aggcgctaat gtagcaatcg gaatatgttc tagaccatcc
     2821 atcactaagc gatcatagat ttcgtcggaa taaataatca ggttattttg tcgagctact
     2881 tcaacgattt cttctaataa ttcttttgga taaagtgccc cagtaggatt attaggatta
     2941 atgataacaa tagcttttgt ccgactcgtt atttttgatt tgatatcatc aatatcagga
     3001 taccattctg cctcttcatc gcaaatataa tgaacaggtg tgcctccagc taatgcaata
     3061 gaagccgtcc acaacggata gtccggcatt ggaaccagta cttcatctcc attgtccagc
     3121 aacccctgca tacacatcgt gatcaattcg ctcactccgt tgccggtgta gatatcattg
     3181 atcgtcacat tcggaaaatg tttcagttgg caatattgct caattgcttt tctagcagaa
     3241 aagatcccct tggaatctga gtagccttct gagtcacggg cattcatgat caaatcacga
     3301 atgacttcgt ttggtgcttc aaatccaaaa ggtgcgggat ttcccgtgtt caattttaaa
     3361 atactaatgc cctcttcttg catccgctcc gcttcttcta gaacgggacc gcgaacatcg
     3421 taactgacac cttctaattt gttggatttt tcaaattctc tcatcactta gccaatccct
     3481 catttcaaaa agttagaact ttccaaattt tttgttattt actatttcaa tatcatactc
     3541 catcctagaa aattttgcca cttatttagg aaaaacgtaa gtattaaaaa aacacaaaca
     3601 agcgttgaga acttaattgt catgatagtc attccataga ttcgctgccc aatccattgc
     3661 aattccacaa atgattccta gcataaaacc aagcaaaaaa cgtccgaatg caagtccaat
     3721 caatacacct aagatcattc ccagtcctga aaattctccg tcatatttct ccatcttaat
     3781 aagtcctccc atttttgagc ttgacaacta tgtaaaacct cgctatcatt agtgtgttat
     3841 tattacgcag atgtgttgga attggcagac aagcatgatt gagggtcatg tgagcgttag
     3901 ctcgtgtggg ttcgagtccc atcatctgca ctacaactcg tgaagttaat tttgcttcac
     3961 gagttttttt gtttgaacgt ttctttatgc cattatatac atatcactgt atcctttaca
     4021 aaaagaacgt acaatcatgt aaacagcctg aggtgagtat atgaaggtcg gaaacaagct
     4081 actcgtagaa acttgcaagt gttaaaacaa ttaatcgaaa aacgagtaaa atccctcacc
     4141 taatactaaa gcgagggatt ttttgtatat tatctgttta tcaccgttat tataaaggta
     4201 caaataccaa gcacggttaa tccaaattgc ataaattcat ttttttgtac actcatgctt
     4261 ttcattagct ctttaactgc cattagtact aagatggcga taacaacata aagtatatag
     4321 tacgtccgca ttccggaagc ccatactgtg ggagaaaatc ccataattaa ccttgaacaa
     4381 aatcccatta tcatcaaaat aactaaaaaa atagaagttt tcttattgtc aaaacttaaa
     4441 taaattccaa caattaaaca tagtaataat gccaagacta ctaaagtagc tatccaagta
     4501 cctggataaa aaagtgacag tttcgttcct aactctgtaa agagattatt caggttacta
     4561 ctactccaaa tcattgccct tttatttcca ttgacgtaag taaagctttg acccattgta
     4621 ttaccaaaat aaataatcag gtttaagaaa aacggtaatg cagtcaatat acgcacataa
     4681 tagttttgac atttcctata tgttagaagg aaaattaaga aaaatagcaa taaaaataag
     4741 atattcatgt ctaaaaaaaa cggctttcca aatgatgaaa tacctaaatc taacttatta
     4801 agaaagttga aatttttata ttcaggaaac catttattaa tttcatgtgc agcacgtaat
     4861 gcattccctg gagttgtcaa agagaaaatt aattctgcta agcttattat tgaaaatact
     4921 gataacttat aattatatcg tccattgaca atcaaatata aactaactat acttgttaga
     4981 acaaaaaaac aggcgttgac ttgttcttga ttagttaaaa atatcaataa aggaatactt
     5041 acccaatata tttttctatt tatttcttct cctcttaaga gttgaaaaaa cggataaaaa
     5101 gttagtaaac taaatgctac tggccactga tagttcaagg tggttgctct ccaaccggtt
     5161 tcccccatta ctgtcaatgg tattaaacag tatatagagc aaaccaataa taaattttta
     5221 acatttattt tctcaaaaac ata
//
LOCUS       DAZULR010000101         5234 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.107, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000101 DAZULR010000000
VERSION     DAZULR010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5234)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5234)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5234
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.107"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            120..1754
                     /locus_tag="ACG8ZV_002700"
     CDS             120..1754
                     /locus_tag="ACG8ZV_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HFS4997952.1"
                     /translation="MRWYMNLKKIFSVKIFIVYAFVSLLYLFPAFKNMEIFGFYDTAF
                     HINRALSLESIFSSPINFETFRSYGMQVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLY
                     IVTLITLFICHYVMYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILPL
                     ILLGFIKLYDSKKESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEIF
                     LIIKLIKAAIVTLLLSLAFIGPMIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDS
                     ELLSFGIGLTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLN
                     IIQAPWRFMIFSTLFISFSVSLFISPQLEKFSYTRRRNFILLLILAISILNYSSVVNM
                     VKEMNFQGTYSNEQMENKLEEFENFDYVPIGYKKDQLLLKNHQVTEDGQVIYSSFSPN
                     KDEITFTFKSSKGKTIVLPVFRYKGLTVTVNSKNATVLKQGGPFVTVKSESGINKVTI
                     RYSYTFFSKISLFISIITLIVLLFYCIKLKIRTSHE"
     gene            complement(2021..3190)
                     /locus_tag="ACG8ZV_002701"
     CDS             complement(2021..3190)
                     /locus_tag="ACG8ZV_002701"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFS4997953.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            3394..4569
                     /gene="mltG"
                     /locus_tag="ACG8ZV_002702"
     CDS             3394..4569
                     /gene="mltG"
                     /locus_tag="ACG8ZV_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HFS4997954.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            4705..5184
                     /gene="greA"
                     /locus_tag="ACG8ZV_002703"
     CDS             4705..5184
                     /gene="greA"
                     /locus_tag="ACG8ZV_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HFS4997955.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
BASE COUNT         1797 a          770 c          897 g         1770 t
ORIGIN      
        1 aaacactact tttgtaatat aaaaaatatt ttattaataa taaaattaat cacattttat
       61 atagtgacta atctagtgtt ttaaaaaaat aaatgatact atatgtaata taaaaaaaca
      121 tgaggtggta tatgaatttg aaaaaaattt tttctgtaaa aatatttata gtttatgcat
      181 ttgttagttt attatattta tttccagcat ttaaaaacat ggaaatattt ggcttttatg
      241 atacggcatt tcacattaat cgtgcgttaa gtttagaatc tatttttagc tcccctatta
      301 attttgaaac gtttagatca tatggcatgc aagtaaataa tttttaccca tggttaactc
      361 tatatccttt atttttattg atcaagttta ctaatttagc aataggctat aacctttttc
      421 tttatattgt tacgctcatt actctattta tatgtcatta tgtaatgtat gaaattacca
      481 aaaaacatgt tactagctcc tttttcgcta ttatatatac aacatcttct tttaggagtg
      541 tagaaatatt tcttcgaggg gcaatggggg aattactcgc aatgtcaata cttcctctta
      601 ttttactcgg gtttataaag ctttacgact caaaaaaaga atcttgggtt atgttggcga
      661 ttagcatgac tttattaatt tacactcatg ttctttctgt agctatgact atggtaatga
      721 ttataattgc tttaattatt caattttatc ggaaaaagaa aatagaaatc ttcttaatta
      781 ttaaattaat aaaagctgct atagttactt tacttctttc actagcgttt ataggtccta
      841 tgattgagca gacattgtat caagatctga atagacctta tgtggatata ttacaaaaaa
      901 gagcaattta tctgggtaaa gagtttttga ttggaagtat agattcagaa ttactatcat
      961 ttggtattgg cttaactttg cttatttgtt taattatact aacatttaac tttaaaaaat
     1021 taggaatctt atctaaaatc acttatataa tgggtataat atctattcta ctttgtacaa
     1081 aaatatttcc atggtttgcc ttacaaaata ctcctttaaa tattattcaa gctccttggc
     1141 gttttatgat attttcaaca ttgttcatat ctttttcagt atctctattt atttctccac
     1201 agttggaaaa attttcttat acaaggagaa gaaattttat actattatta atattagcta
     1261 tttcaatttt aaattattca tcagtagtta acatggtgaa agaaatgaat tttcaaggaa
     1321 cttattctaa tgaacaaatg gaaaataaac ttgaagaatt tgagaatttt gattatgtac
     1381 ctataggcta taaaaaagat caattgcttt tgaaaaacca tcaagttaca gaagatggtc
     1441 aagttattta tagtagcttt tctccaaata aagatgaaat tacatttacg tttaaatctt
     1501 caaaaggcaa aacaatagtt ttacctgtat tccggtataa aggattaacg gttactgtta
     1561 attcaaaaaa tgctacagta ctaaaacaag gaggtccttt tgttacagta aaaagtgaaa
     1621 gtggaataaa taaagtaaca atcaggtatt catacacatt tttttctaaa atctcattat
     1681 ttatttctat aatcacgcta attgttcttc ttttttattg cataaaatta aaaataagaa
     1741 caagccatga atgatttgct agcacatatt ttagcaatct aaagatacta ttttagattt
     1801 aataggccct ttgtcaaata atgttggtaa agagaaatct tagaataatt tggacagaac
     1861 agaaagaaga acacctcttt ctgttctgtt tatttggaat taaagtctgt agcaaaaatt
     1921 gatttttaga tttgtcccac actctttcct acgtttagtc gagtactttt tttaagcaaa
     1981 tgctattcaa agaagtagta tttgctatct tttcatcata tcagctattt gccaacttag
     2041 tagttccttc catcaggtca tagatttggt ttcttagatc agcagtaggc agtttgatag
     2101 ttttgtcagc ttttatattg ctttccatga tgatagcatc ctgtgaatct ttgctaaata
     2161 tagcagatgt atcaaaagag tcgatatttc cttgcgacag gatataatta tctccgctat
     2221 ataccccacc actatatgga tgtccattcg cattttcacg ccataatgag aagagtaagt
     2281 ctttggaaac tagttttcca gataaaactt gtgtaaacag cgtatttaaa tcatagacgg
     2341 acatactgat attaccagtc cctaattcgt tatggatctc tgtttcagat tctgtcagtg
     2401 gtttaaagta atcatcctct ttagacattt gataggatag tgcatgattg gatgaatttt
     2461 tgacttggtc ataaaatttt gtatgctgta atcctaaagg ttcgatgata tcatcggtca
     2521 ataatttttc atacggttga tttgttaatt tgatcaaaat tccagtcaat atggtaaagt
     2581 tcaatgaatc ataatgagag gtctgataat ctgtaaattt taagtgctga atcgcaaatt
     2641 gaacgacttc ttcatcagtc atcggtatgg ttggagaagc agttcggtgc aagcctgagc
     2701 gcatatacag caagtcacgg atagtaattt gctggctgcc agcaatttgt ggatagaatt
     2761 gagccagctt agtatctaaa gaaaggtgcc cacgctcgac ttgttttaaa atcaaaagag
     2821 tagtcaatgc tttttgaacc gaaccaatct gataataaag agaaggatca tttggttgtt
     2881 gcgtgagttt attcgcatag ccatagcctt tttccatgat gatgcgatta tttttcttta
     2941 cgtaaattga gccaatataa tcattttttc ttaatagttg atcgattttt tcaacgagct
     3001 gttgttcatt ggtagtcagt atcaactttt tttgagctga ttgagcatgg gcaactatct
     3061 gagagtgttc attattgtaa aattgccatc caagaatagt tcctgtagag aacgcactaa
     3121 ggctaaacaa cacgacaacg atcattaaaa atgaatattt tcttttttta gcatgttttc
     3181 cttttttcat aatagtttat ttagtctcct ttctttttta cagaaagaat aaagctaaaa
     3241 tagcttgtat cttgataaca tttattttaa tcttatagta atggatttac tacttacatt
     3301 tttgatagaa tatttaaata aaatcattca cgccaattca aatatcatgt ataatgaata
     3361 aagttacgaa cttgatagta aggaggagtt gttttgtcag gaaacaaaca acacccaagt
     3421 aaagataaaa aagaagccag taaggcagct acagcagata taatcgacaa gcggagaaat
     3481 ctgcgtaaaa aagaagataa gattgtgagg aagatcattt tagtgattgc tcttacatta
     3541 ttgattattg gcggatttct tggatttacc gtgtatcgtt atgtagatag cgggttgaag
     3601 cctttagata aatcagatga ccaattagtc caagtcgaga tcccgagtgg ctcttctaac
     3661 aagcagattg gtgagatttt ggagaaggac aatattatta aaagcgggat tgttttcaat
     3721 tattatacaa aatttaaaaa tttaactggc tttcaagctg gctattatca gttagcgcct
     3781 aatatgactc ttgacgagat tggcaaacag ttgcaagaag gcggtacttc tgagccaaca
     3841 aaagttgcag atgggaaaat tgccattcca gaagggtacg atatcgatca gattgctgaa
     3901 cgggtagcga aggtaactgg taaagacaag aaagaatttt tagatttagt gaatgatgag
     3961 actttcttta acgagttgca ccaaaaattc ccagaactgt tggaaagtgc atctaaagct
     4021 gagaacacaa aataccgttt ggaaggttac ttattcccag ccacatatga ttattacacg
     4081 agtacttcgc ttaaggatct agtgattgaa atggtgaaca agacgaatac ggtcatgcaa
     4141 aactattatt cagctatcaa gcagaaaaat ttgactgtac aagaagtttt aactctagct
     4201 tctctagttg aaaaagaagg cgtaaaagaa aatgatcgta aaaacattgc acaagtcttc
     4261 tttaaccgaa tcaaagcaaa tatgccactt cagtcagata tctctgtttt atacgcatta
     4321 ggtgaacaca aagaattagt gacgtatgaa gatacagctg tagattcacc atataatttg
     4381 tataccaata ccggctatgg acctggacct tttgacaatc caagcgaaga ggcaatcaag
     4441 gcagtattag aaccagcaga aaatgactat tattatttcg tagcagatac gagcactgga
     4501 aatgtttatt tcgctaaaac ttatgaagaa catatggaat tagtggaaaa atatgtaaat
     4561 aattcttaga aaaacaggct ctagacattg atcattttta gaaaaacatt tacatttgaa
     4621 gaaaagcgtg gtaatctttt ttggactata ttcctcaaaa gattaccttt tgcggtattt
     4681 tatcgaaaaa aggagacgtt acacatggta gagaaagttt atccaatgac tctagaaggt
     4741 aaagaaaaat tagaaaaaga attagaagaa ctaaaaacag tcaaacgcgg agaaatcatt
     4801 gaacgaatca aaattgcccg cggtttcgga gatctttccg aaaactctga atatgaatca
     4861 gcgaaagatg aacaagcatt tgttgaagga agaatcacaa caattgaaaa tatgattcgt
     4921 tttgctcaaa tcatcgataa cgacggtgta gatgcagatg aggtatcaat tggtaaaaca
     4981 gttacattca tcgaactacc agatggagaa gaagaagagt acacgattgt cggaagcgct
     5041 gaagcagatc cgttttctgg caaaatttcc aatgattctc ctattgcgca agcattgatt
     5101 ggcaaacgta aaaatgatga agtaactatt gctactccag gtggcgatat gttagttaaa
     5161 atcgtcaaag tagaacaagc gtagtctgac tgaaagatct agagagttca tcttactgat
     5221 gatacactct agat
//
LOCUS       DAZULR010000102         5201 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.108, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000102 DAZULR010000000
VERSION     DAZULR010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5201)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5201)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5201
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.108"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            25..696
                     /locus_tag="ACG8ZV_002704"
     CDS             25..696
                     /locus_tag="ACG8ZV_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFS4997956.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            755..1195
                     /locus_tag="ACG8ZV_002705"
     CDS             755..1195
                     /locus_tag="ACG8ZV_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997957.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            1207..1875
                     /locus_tag="ACG8ZV_002706"
     CDS             1207..1875
                     /locus_tag="ACG8ZV_002706"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HFS4997958.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            1939..2562
                     /locus_tag="ACG8ZV_002707"
     CDS             1939..2562
                     /locus_tag="ACG8ZV_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HFS4997959.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            2618..3004
                     /locus_tag="ACG8ZV_002708"
     CDS             2618..3004
                     /locus_tag="ACG8ZV_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HFS4997960.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            3217..4608
                     /locus_tag="ACG8ZV_002709"
     CDS             3217..4608
                     /locus_tag="ACG8ZV_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HFS4997961.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
BASE COUNT         1729 a          861 c         1095 g         1516 t
ORIGIN      
        1 aatgatgaaa aaagggggag aaaaatgaat tttttagttg ttttaaaaga tactctgatt
       61 gagcgatcta catttctata tgttcaattg caggaaaata aaacattgct gcatttttca
      121 ccagagttcc atctagaggg gctaacatta ggagaaatct atcaagcaga agggctgtcg
      181 gctgttttgc acttttttaa ggtagaattg gaattaccag taaaagatta tatcgagctt
      241 tctcttgaat cttgggatcg agcagtggtt gaactgtttc cagaaggttt aatgatcgat
      301 acaaacgatg ggaagatcca tctgactgca gcagaactgc aaaaacaaat gcgttatcaa
      361 atagatgacg aaaattcttt ttctattttt agacgtcagc aaaagattct aaaaagcttt
      421 ttaaaagtga tcagtaaaaa acggaatctg atcaaaacga cacagctgtt gaaaaaatat
      481 ccaggtctgc ttcacacgtc tattcaattt cctcaattga ttacgatgat ccatcgtttt
      541 atacgtatgc aacagctacc atctaagaag ctgtttcttc cattgacgga cacatttcga
      601 gtagtcaaca gagaagataa aaagaaagtg attgtgattg actttaccag aaatcggaat
      661 gtccttcacc aagttgcaat ggaaaaggcc aattaaggct ttttcttttt ggattttttt
      721 gtcataataa atattagatg atggaggaga taatatgatg caaacatggt tagaaaggct
      781 aatacgattt cagcagaact atcacaaact tatgcaggga agatatgcga aatttgatca
      841 gttgaatcgc ggtctattga tcgctgcgct tgtctttagt ttgctaagtc gttggttgcc
      901 ctatagaatc ggacaattgt tgttcatcgt ctttttcgga tggatgatat ttcgtttcct
      961 atcaaaaaaa atctacccca gactaaatga gaatcaacgt tatttgaaat atcttgatag
     1021 agtcaaagaa aaatatcatc agataaaaaa caaaaagcaa gtcaaaatgg atcgaaaaag
     1081 ttatactttt tttgagtgcc cgaattgtca tcaaaagcag cgtgcaccta aaggaaaagg
     1141 acgaatacgt gtgacatgca aaacatgtgg tataaaattc gaaacgaatg tttaagggag
     1201 aaaagaatga aattagtatt attacgtcat ggcgaaagcg aagcaaattt tgaaaattac
     1261 tggacaggat ggctagatgt cgccttaaca gaaaaaggaa aagaacaagc agcagttgcc
     1321 ggtcaaaaaa tgcttgaagc cggacttcaa ttcgatgccg tttatacctc tgttttgaaa
     1381 cgtgcgattc ttaccggaca agtcgcacta gaagaaatgg gtcagttatg gcttcctata
     1441 ataaaaacat ggcgtctaaa tgaacggcat tatggggatc ttgtgggtaa aaacaaagat
     1501 aagatgaaag aaatatacgg aaaagatcaa gtaaaaacat ggcgcagagg atatacggaa
     1561 gttccgccgt taaccgcaga aaatagattt gaccgcagat atgatcactt ggatccgcat
     1621 ttgatcccat acggagaaag tctggaaatg acagtgaatc ggatcattcc cttatggcaa
     1681 gatcatctag caccaaaact aaaagatcgg caagatttac tagttgtggg tcatggtaat
     1741 agcatccgag cactgacaaa atatttagaa gatgttcctg aagatcaaat ggatacgatc
     1801 gatatcccaa atgcacaacc aatccagtat acattagcag atgatttgac aattctggac
     1861 aaaaaaatac tttaaagaac acctttatct aaaagtgaga gatagaaaaa agaagcaaag
     1921 gaatggaaca aaaggaacat gaaaaattat atatgggact ttgatggtac attgtttgat
     1981 acgtatcccg caatggtaga tggtgcatgg caagcactaa aagattttgg tatcagtatg
     2041 gacaaaaaag aaatctactt caaaatgaaa aagtattcta ctagttattt gatcaatgaa
     2101 tcaaacttga atgccagaga gtttaatgaa ttatttcacc gatatgaaaa agaaagtacg
     2161 gaagtttccc gtccatttcc agaaacgaaa caagtactgg aaatgctaaa agacaacggc
     2221 ggtcgtcatt tcatcctgac ccaccgtttg acagaatcaa catggggcct gttaaaagaa
     2281 catcgattgg cacatctgat tgaggaagta gtagggatcg atcaggactt tcctcgtaaa
     2341 cctgatccag catctttaaa ttatttgatc gatacttttc atttagaaag aacagacacg
     2401 atgatgatcg gcgatcgtcg tttagatatc gaagcaggga aaaatgcagg agtcgctact
     2461 tgtctttacg acatcgatca ttttctgggt gagatcccgg cagattatgt ggtaggaaat
     2521 ctgaatgaaa tccttacctt gcagagcatc attaaaaagt agtatcccct ttcaaaggag
     2581 atatgttata attttcataa aggagtgata aaattatatg gaaatcagaa gacaaaaaga
     2641 agttgtagaa gcatttcatt atgatatgag attgccgaac caagaagtag aaacagattt
     2701 gaaagtaggc ttctcgcctt taaaagaaac gatcgaaaac tatccgaaag aacatagcat
     2761 cgtaggagca cgcttagagt tccgtttagt gtttgataca tatgttttat ctggaagtgt
     2821 gagtcagatc aatcatatcc tcaatcggaa aattgaaggt caaaatgatg tcacacaaga
     2881 agaagtggac gagctagtag caccgttatt cgatatcgta cgccgaatgt cttatgaggt
     2941 gacagagatc gccttagatc agcctggggt aaaattgaat tttcaatcag aaaaacaaga
     3001 atagacagta aaaacatacc tgcgatagat taaagctatc acaggtatgt ttttttatta
     3061 ctaattgtaa gcaaaaagaa tgtcatttcg ataaaaatcg tctaaaatat aaaagtcact
     3121 gaaaaaaatt ttttcaggag gatggttgaa gaatcattct cgggaacctt tacttccttc
     3181 gatggacttg tcattaataa tatgaggagg agaaaaatga caacactcat cacagtttta
     3241 gtggttctag tttttgcggc attattatat gtgttctatc gtatgcaaaa gcgccataca
     3301 aaattttcaa cacgcgtctt tacagcatta ggagttggta tcgtctttgg cggtctgctt
     3361 caattgatct ttggtgtaga cgacaaagtc gttactcaat caatggaatg gatcgggatt
     3421 gtaggtcaag gatatgtatc attcttgcaa atgctagtta tgcctttagt gtttatttcg
     3481 atcattggtg cattcacaaa aatgaaagtt tctgaaaagc tagggaaaat tagtgcgact
     3541 gtattgactt ctttacttgg aacaacagct attgcagcat tgatcggaat tggttcaaca
     3601 atgctgttcg gactccaagg agctaaattc acacaaggag ctgcagaaac agcacgaatc
     3661 tctgaactgg caacacgtca ggaaacagtt gaaaacttat cgattccaca gcagatttta
     3721 tcctttatcc ctaaaaacgt ttttgctgat ttagcaggta gtcgtgcaac aagtacgatt
     3781 ggagtcgtta ttttcgcggc atttgtcgga atcgcttatc taggcgtgaa aagaaaagcg
     3841 ccaaaagaag cagcattctt ttcagattta gtcgacagtc tgtataaaat cattatgcgg
     3901 atcgtgacgc ttgttttgcg tttgacacct tatggagtat ttgctttgat gacaaacgtt
     3961 ttggcaacaa gtgattttgc agctatcgtc aatttaggta aatttgtcgt tgcttcttac
     4021 gtagcattgc ttgctgtttt gattgtccac tcactgattt tgattggtgc aaaagtcaat
     4081 ccaatcaact atttcaaaaa agcctttccg gtattgagct ttgcgtttac ttcacgttca
     4141 agtgctggag ctttgccatt gaatatcgag actcagacaa aagctttagg agtagatgat
     4201 gcaacagcta atttctcagc aagttttggt ttgtctattg gacaaaacgg ctgtgctggc
     4261 gtttatccag ctatgttggc aacgatcgtc gcaccagcag ctggagtgaa tgtctttagt
     4321 ttggaattta ttttgatgct tgtggcaatt gtaacaatca gttcttttgg tgtagctgga
     4381 gtcggtgggg gcgcaacatt tgcttcactg atcgttttag gggcaatgaa cttgccagta
     4441 gcaatcgttg ggttagttat ctctgttgaa ccattaatcg atatggcacg tacagcagta
     4501 aacgtcagcg gtagcatggt agctggtatc gtgacaagtg cacgcatcaa agatttagat
     4561 cgcgatgtca tcaatgatga ttctaaagtg atcgatgtga atgcatagtc aaaaagaggt
     4621 tgtgatagaa gtggtcagct ttaagaaata agaagaagtt tcctaaaaat agtttctcaa
     4681 atttttgtga aatttcggct tatttccgag aagctacttc tgaaacaccg tgaataagag
     4741 gttgtgaaaa agctgccctg catcaagtaa taagaacagc caaacaaaaa tagttcctca
     4801 tattttacgt ttggttgagc ttattaccgc agatgcaagc ttttgaacac cgtttaagaa
     4861 agaggtcgtg agcctgccgt ttcactctga gtcacaaaga gcaatttcaa aaaatagctt
     4921 ctcatgtttg ttgaatattg tgtcttgtga ccgaggagtt gtcaggagaa caccgtttac
     4981 cagaggttgt gacttgtttt tagtcacgac ctcttttttt atttattcca tataaataca
     5041 cattatttat tccgaaaagt gaaagcgcaa ataacaaaaa caaccaactt atttattatt
     5101 aaagaaaagc gtatttaagt aggacgattc tgttgagagc tttcgtagat tttcccattt
     5161 tcctatggta aactgacaaa gttgagaatg ttagaacaga t
//
LOCUS       DAZULR010000103         5168 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.109, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000103 DAZULR010000000
VERSION     DAZULR010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5168)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5168)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5168
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.109"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(128..1090)
                     /locus_tag="ACG8ZV_002710"
     CDS             complement(128..1090)
                     /locus_tag="ACG8ZV_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFS4997962.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1092..2531)
                     /locus_tag="ACG8ZV_002711"
     CDS             complement(1092..2531)
                     /locus_tag="ACG8ZV_002711"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004564 - beta-fructofuranosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HFS4997963.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2716..4662
                     /locus_tag="ACG8ZV_002712"
     CDS             2716..4662
                     /locus_tag="ACG8ZV_002712"
                     /EC_number="2.7.1.211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-specific PTS transporter subunit IIBC"
                     /protein_id="HFS4997964.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKINGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
     gene            4926..>5168
                     /locus_tag="ACG8ZV_002713"
     CDS             4926..>5168
                     /locus_tag="ACG8ZV_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFS4997965.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPK"
BASE COUNT         1667 a          875 c          853 g         1773 t
ORIGIN      
        1 ctccaaaaaa gtctaacttt tgggggtcac tacaagttga caactccttt ttgtttacaa
       61 atcaattgga tatctacaaa ttgtattttc taacgaattt tatagacatt aaaaaattaa
      121 tttaacgtta aatacttcct ccagaaagta ttgagattgg taaaatataa tccttatttg
      181 tcttttcgcc tttaattttt ttcagaagaa tatcaacaat aagacttgca atttcatcaa
      241 ttggttgtct tattgttgtc aattgtggga aaaatttctc aataaaagag gtaccatcgt
      301 atccaataat ttttaaatct tctgggatat taagtttaag ttgatgagca attttcatag
      361 tgagaatggc tgttaaatca tcagaaacaa aaataccatc tggtttgtga tttataatag
      421 ttgactttat ttccatttca cgacggatag tagacagatt attaggaatt ttgaaaattt
      481 ttccatttgg attttgaaaa gaaaaaccta gtgcacgtaa ttctgtggga gaatccgtgt
      541 tatcatttcc tgtaatcata atggtatttt gacaaccatt tttttgtaaa gtcttagctg
      601 caagttttcc cccttcaaag ttatctgaag aaacaatgga aacattagga gctaaatttc
      661 tatcaaaagc aacaataggt gctctcacac gctcataatc agcaattcca agattatggc
      721 ttgatgagat tatgccatca acttggttgg cttcaagcat ttcaatgtat tctctctctt
      781 tagcaggatc attttgacta ttgcaaataa tcgttttata tccatgttta aataactcta
      841 tttcgagata ctcaatgagt tcagagtaaa agatattact aatattagga aaaataagac
      901 caataagctg aggtgacttt ccttgaagtc cacgtgctaa attatttggt ttataaccaa
      961 gagttttcat agcttcatga actttttgtt ttgttttttc tgataaatat cccttattat
     1021 taatgacgcg tgaaacggtt gttgggctaa ctccagctaa ttcagcgaca tcagttaatt
     1081 ttgctaccat tttaatattt taattcaaag tattttccag taggttcgcc tgatttgatt
     1141 tgaataccat tttggtgatt ttcagggaat acacgactag taaacacttt ttctccttta
     1201 ttaataaaaa tctcaatgat tgagttatct acaaaaatgt tagcagttgt ttctttagta
     1261 tcaattgagc attcacgaat cgtaccaaag tcagtggcat attgaatgcc tgctttgctg
     1321 cgatctaaaa taatttttcc ttctttggta tctacaatca agctaagtcc atttccttta
     1381 ctatcagaga aaagaagtaa ctccgatttc tgatttggag gaaaagttag ttcaagctca
     1441 taagtattat ttgtttctgc ttttgctgta aattgttcag aactagcacg taatgatgta
     1501 atagcttcta ctggatattg gtaaagttta ccatctttta ttgaaagttc ttttacaaga
     1561 ctcattgctc cctgataatc atacttatca gttggataat cgatatcagg tagtccaatc
     1621 caactgacaa tcagagcacg accatcagga gtattgaatc cttgagtcgc atacgcttca
     1681 aatccataat caagattttg aatttctgaa gcgcccacaa gttttacttt ttctatgtca
     1741 agcgattgac agatcttaaa agtattcgga tagatattcc cataatttag ctcagattta
     1801 tccaaccctt gaggacaata aatgagaaca ggttttttgt ctacaaatac tagatttgga
     1861 cactcaatca tgtattctga accagtgccg ccaaaatcaa ggttgccaac ttcctcccat
     1921 gtttccacgt tattgtcatc cgctttgtaa agtttgataa agcctgattt ttctaaattt
     1981 tgtgctccaa caatcgcata caattgtcct tcataattaa acatttgtgg atcacgaaaa
     2041 tgatcagtta catcagcagg tttatgaata agaacattct cacctttcgt aatgttgtag
     2101 tctttatcca tccatgctcc gatttgaagt gtatcacgtt cccaattttc atttcgaacg
     2161 tttcctgtat agagtaagaa tagattcccc tctatttcat atgcagaacc ggaataagcg
     2221 ccgtggctat ctcgttttgt gtctggaaga agttctgctc ctgttacatg aaaatgaact
     2281 aaatcatctg attcattgtg tacccattct ttcaacccat gagcagctcc aaatggccaa
     2341 ttttgataaa aaagcgtata ttttccgtta aaaaaagaaa aaccattagg atcgtttaac
     2401 aatcctgttt taggttcgat atgatagcta gcacgccaag gtgatcgttt tacattatcc
     2461 ttaattttat ccatctcatc tttagtccaa tcagaataag cacgatatcg tatttctcga
     2521 ggtaagttca tattttactc cttcaattta tctttttaca actagtatgg taaacgtttt
     2581 ccgttgaaaa atcaatcatt tcatttaaaa aaataaacta tatgacaaac gtttgacata
     2641 tttttaagat atgctaaaat aaatttgcat ttcagtgaac cgttttcacg taaaaataaa
     2701 aaaggagtga ttcgaatgaa ttacagtaaa gtagcttccg acgtaataca agcggtcgga
     2761 aaagataacc ttattgcagc tgcacactgc gctacacgtc ttcgtctcgt actaaaagat
     2821 gacacgaaag tgaatcaaaa agctttagac gaaaatccag atgtgaaaag cacatttaaa
     2881 attaatggac aatatcaagt gattatcggt gcaggtgatg ttaatttcgt ttatgacgaa
     2941 cttatcaaaa aaactggact ttcggaaatt tcaacagatg atttaaaaca aattgctagt
     3001 aaagataaaa aattcaaccc cattatggca ttaattaaat tattatcaga tatttttgtt
     3061 ccaattatac ctgcccttgt tgcaggtggt ttattaatgg cattacaaaa ctttttaaca
     3121 gctgctggac tttttggacc aaaatcaatt gaagaaatgt atcctgcgat tgaaggtatt
     3181 tcctcaatga tccaactgat gtccgctgca ccattcatgt tcttaccaat tttagtaggt
     3241 atttcagctg ctaaacgttt tggagcaaac caatttcttg gtgctgcaat tggtatgatc
     3301 atgacaacac cagatcttgg tggctcaact gaatattgga atatttttgg ttatcatgtt
     3361 tcacaaacaa actatgctta tcaagttatt ccagttttag cagctgtttg gatattatct
     3421 atattagaaa aattctttca taaaaaattg ccatcatcta ttgactttac attcacgcca
     3481 ttattatcag taatgattac tggatttttg actttcacag ttattggccc tgtaatgtta
     3541 ttgttgtcta atggaattac agacattatt gtttggctat ataacactac tggatttatt
     3601 ggaatgggta tttttggagg aacatattca cttatagtca tgactggttt acatcaatca
     3661 tttccagcta ttgaaactca attactttca gcgtggacaa atggtatcgg acatggagac
     3721 tttatctttg tagttgcatc tatggcaaac gttgctcaag gtgctgcaac atttgccatt
     3781 tggttcttaa ctaaaaattc taagacaaaa agtcttgctt cctctgcggg tgtctcagca
     3841 cttcttggaa ttacagagcc tgccttgttc ggagttaact taaaataccg ctttccattc
     3901 ttttgtgctt taattggttc aggaattgct acagcagtag caggattact taaagtagtt
     3961 gctgtttcac ttggttcagc aggtttcttg ggatttcttt caattaatgc aacatctatt
     4021 ccattttacg tattgtgtga attgattagc tttgtagttg cttttgcaat tacttacttc
     4081 tacggtaaaa caaaagctgc tggtatcttt aaagcagaag aaattgctga acaaacacca
     4141 gttaattctt caaaagtagc aacaacagat ccaatatcta ctgatgttga atcaacacaa
     4201 acaaaagttt catcagaaac aattgttagt cccatttctg gtaaagtgat tagtctttct
     4261 tcagtaaatg atccagtctt ttcatcagaa gctatgggaa aagggattgc cattaaacca
     4321 aatggaaaca cggtccattc tccagtagat ggtactattc aactcacgtt tgaaactgga
     4381 catgcttatg gtattaaatc aaataatggt gctgaagttc taattcatat tggtattgat
     4441 actgtatcaa tgggaggaaa aggatttaca caaaaagtta ctactaatca aaaagttaga
     4501 aaaggcgata ttcttggagc atttgaccgt tcaatgattg agaaagaagg tcttgatgat
     4561 acaacaatga ttattgtgac caatacttcg gattattcag aagtaaatat agtagctgaa
     4621 aatacagtca ctgagggtac tgatttactt gaaatcaaat aaatatattt ccctgagtaa
     4681 agatggaatt ttctttccaa aatcaaataa tatagattaa tcaaatattt gagaataaca
     4741 ttttatttaa tcttttcata tatcaattgt atgaaaaatt attagaattt taaaaaatga
     4801 taaaaattca aaaagaaaaa atagtagtta tttacttgtc atgttactaa ataaaaaaat
     4861 aatttaaata tgatatatag tcatttattt agtgatttca ttctaaaata aagggagaaa
     4921 tgtctatgct atacggtgca attgaagcag gcggcacaaa atttgtgtgt gccattggcg
     4981 atgaagaaat gacgatcaag gaaagagtga gctttccgac aacgacacct gaggaaacaa
     5041 tgcctttagt cattgacttc ttcaaacaat accaagcaga tttagcaggg attgggattg
     5101 gctcatttgg gcctatcgat atccatcgcg attccgccac ttatgggtac attacctcga
     5161 ccccgaaa
//
LOCUS       DAZULR010000104         5074 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.110, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000104 DAZULR010000000
VERSION     DAZULR010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5074
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.110"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..564
                     /locus_tag="ACG8ZV_002714"
     CDS             <1..564
                     /locus_tag="ACG8ZV_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997966.1"
                     /translation="LPGVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDK
                     KKKEQVLTQKMEEFTTCYEDMNNIFVDQEKRLTDKNMKKLTRFYQNLPEKQQKEVQEK
                     YEQVKKDVQYFKDTQTEEACCNLFSDTIPFSTSEQERKERQQSVTYERYETLLQQATN
                     IQNPTKKETALNYLESVKEWLDQQQQN"
     gene            complement(685..771)
                     /locus_tag="ACG8ZV_002715"
     CDS             complement(685..771)
                     /locus_tag="ACG8ZV_002715"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HFS4997967.1"
                     /translation="MFERFICPLLVEVCVSLFSYWLNNRNKK"
     gene            1447..2397
                     /locus_tag="ACG8ZV_002716"
     CDS             1447..2397
                     /locus_tag="ACG8ZV_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HFS4997968.1"
                     /translation="MANEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMREKGDKTVR
                     LTFDQLKDLSNYKATANNRFINDLEMTYDKLMDLRFGKRSANGLDIDRFVMFSEFKIR
                     GTAKDPYVDIQVYEKALPLLNNLDEWVRYSLQQFNELQSSYAKTMFRLLKQYRTKGFA
                     YFSKEDFHELLDIPKSYWNNQANVDNRVIKPIRQELTAIFKGLSIKKKYGKGRGKPVV
                     GYQFTFKPEIKKADDFNKHAPTKEEQNKALALADKQKEYEEPATTINEKIKQKKRELE
                     LLQQIKQLEKEKEALEKQTESALSKKEKKSLLSDLDNLFQ"
     gene            2418..2951
                     /locus_tag="ACG8ZV_002717"
     CDS             2418..2951
                     /locus_tag="ACG8ZV_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HFS4997969.1"
                     /translation="MQPQETFTIKELSELFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLGNQMLLDRLHEYEQDNDKNVNIPSKNVVTNKLLDQLREENEFLRE
                     QLALREQNNSHIQKLLDQQQQLTLQANKQIEKLQEKLQLTYTEEAPENDSTTLSEATE
                     TIDKQIDTEKKWWQLWK"
     gene            2967..3137
                     /locus_tag="ACG8ZV_002718"
     CDS             2967..3137
                     /locus_tag="ACG8ZV_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997970.1"
                     /translation="MTRKNLLFGSILLGILGFSPMLLSVINKGNKHGELKLNPNYYNS
                     PNEELFVKETDK"
     gene            3587..4120
                     /locus_tag="ACG8ZV_002719"
     CDS             3587..4120
                     /locus_tag="ACG8ZV_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997971.1"
                     /translation="MKKFTLGVALLTIGAVVLPSTTIVYASENSQVVSLNENNATENV
                     VIEYTEDGMVVTKYEDGYSAEDFANSSDIMTRAAVARWGKKEYTNIAVTTGVAANAIN
                     AAFWAGGKASTSMFGIPGWAIGALLTGASWTKKGASPGNAVAKEWDKNGNGWIGFYYQ
                     RGYDAAGRVVATRYSTL"
     gene            4132..4335
                     /locus_tag="ACG8ZV_002720"
     CDS             4132..4335
                     /locus_tag="ACG8ZV_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997972.1"
                     /translation="MFLISKSLKSLKTFTKKNPQIATIRIFIFAIAVAIIVNMLSGGQ
                     LYKSGLFLVLILVVLDIIKSKKK"
     gene            4657..5037
                     /locus_tag="ACG8ZV_002721"
     CDS             4657..5037
                     /locus_tag="ACG8ZV_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HFS4997973.1"
                     /translation="MSEQHQNLASDHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVAPD
                     DAQRLSENLKIMQKELQKIWQQLK"
BASE COUNT         1841 a          854 c          953 g         1426 t
ORIGIN      
        1 ttgccagggg ttatatttac attatcaatc gttttaagtg gtttattcgg cgttttagag
       61 ggaaataaac gtatttcaag aagtatttta ttaggggata tcactcaaaa gtatgaagca
      121 gcatgtgata aaaagaaaaa ggagcaagtg ttaacacaaa aaatggaaga gtttaccact
      181 tgttatgagg acatgaacaa tatttttgtg gatcaagaga aacgtttaac agataaaaac
      241 atgaaaaaac tcactcgttt ttatcaaaac ttaccagaaa aacagcaaaa agaggtacaa
      301 gaaaaatatg agcaagtaaa aaaagacgtg caatatttta aagatacgca gacagaagaa
      361 gcttgttgta acttatttag cgatacaatc cctttttcaa ccagtgaaca agaacgaaaa
      421 gaacggcaac aatcggtcac atacgaacgt tatgaaacac tgcttcagca agcaacaaac
      481 atacaaaatc caacgaaaaa agaaacggca ttaaattatc tagaaagtgt caaggaatgg
      541 ttggatcagc aacaacaaaa ttgaatttga ttagcaatca tgttaaactg aacctgcaaa
      601 tgatcaaaca ttagatacac gaaagcccca gagaggtcgg attctctggg gctttttttc
      661 aggttgatgt cgcctttatt gattttactt cttgtttcgg ttattcaacc aataactgaa
      721 taaagagaca caaacttcta caagaagggg gcaaatgaac cgttcaaaca ttagatacac
      781 ctccttccag tcgcaagact gtcggatagg cgacaagtta ttatacctta caaaataaaa
      841 tctgtgtggt gtttttaagt atcccttatt ttcgggttgt tagggcttgc cctgaccgcc
      901 tgtaaggcgc tttaagaaca agataaggtt ttttacccaa gactgtctta aaacgactta
      961 gacgagctat cagaggcttc ccccacctcc gttactgact tgtttttagc aaaggagcct
     1021 ttaggcgact gcgcagtaca atgtgagagc atagcgatca cactttttta gcgaccgtag
     1081 ggagcaaggt tttgaattgg cagttttgaa aaatgcgcga acctgttggt agaaaaaaga
     1141 agtggttttt aggcgggaaa ttttgtcacc ctcttttata atctcttttt aaaccttttt
     1201 ttaaacctct ttaccgtcgg ctgtgtcctt actccttcaa tggatacagc gttttataaa
     1261 ctacattttg tctgctttta aactacattt tgtctgcttt taaactacat tttgtctgct
     1321 tttaaactac attttgtctg cttttaaact ctttttttgc actcacgtat gttataatat
     1381 gcattatcac agacaaaacg ttgtttataa cgtctgtatc cattgaagga gtaaggagga
     1441 atatctttgg caaatgaaat cgtgaaatac catcatgaat taaataccat tccgttgcgg
     1501 aaatttacac cagttgaaat gaatctattt ttctctattg tgtctagaat gcgcgaaaaa
     1561 ggcgataaaa cagtccgtct tacttttgac caactaaaag atttaagtaa ttataaagca
     1621 actgctaata atcgtttcat taatgattta gaaatgactt atgataaatt aatggattta
     1681 cgttttggta aaagaagtgc taatgggctc gatatagata gattcgttat gtttagtgag
     1741 tttaaaatac gtggaactgc taaagatcca tatgtagaca tacaagttta cgaaaaagct
     1801 ttacctttac taaacaattt agatgagtgg gttcgctatt cactccaaca atttaacgaa
     1861 ttacaaagta gctatgcaaa gactatgttt cgattactaa aacaatatcg aactaaaggt
     1921 tttgcttatt tttctaaaga ggattttcat gaactattag atattccaaa aagttactgg
     1981 aacaaccaag caaacgttga taatcgtgtt ataaagccta tacgacagga attaaccgca
     2041 atcttcaaag gattatcaat caaaaagaaa tacggaaaag ggcgaggaaa acctgtcgtt
     2101 ggctatcaat ttacgtttaa accagaaatc aaaaaagcag atgattttaa taaacatgca
     2161 ccaaccaaag aagaacaaaa taaagcattg gctttagctg ataaacaaaa agaatacgaa
     2221 gaacctgcta caacaattaa cgaaaaaatc aaacagaaga aacgagaact tgaactcctc
     2281 caacaaatca aacaactaga aaaagagaaa gaagctcttg aaaaacaaac agagtccgca
     2341 ctttcgaaaa aagagaaaaa aagtttatta tctgatttag ataatttatt ccagtagcaa
     2401 cctaggaggc aaccagtatg caaccacaag aaacctttac aataaaggaa ttgtcagaac
     2461 tttttaagat gagtaggcaa gcaatatcga aacatatcca aaaattagat tcttccatga
     2521 tagctaaaaa tgagcgtggt tataaggttg tattgcgttc tggagtattg caacttgctc
     2581 gcaacttagg caaccaaatg ttgctagata ggttgcacga gtacgaacaa gacaacgata
     2641 aaaatgttaa tataccaagc aaaaacgtgg ttacaaacaa gttgctagat cagttgcgtg
     2701 aagaaaatga atttttacga gaacaacttg ccctcagaga gcaaaataat tctcatatac
     2761 aaaaactact cgaccagcaa caacaactca ccctacaagc caacaaacaa atcgaaaaac
     2821 tgcaagaaaa actacagttg acttatacag aagaagctcc agagaatgac tcaacgactc
     2881 tttctgaagc aacagaaaca atagacaaac aaattgatac tgaaaaaaaa tggtggcaac
     2941 tttggaaata actggaggga acattcatga caagaaaaaa tcttctattc ggttctattt
     3001 tactaggaat tctaggattc agtccgatgt tattgtcagt gatcaataaa gggaataaac
     3061 atggtgaatt gaaattgaat ccaaattatt acaacagtcc taacgaagaa ttgtttgtaa
     3121 aagaaacaga taaataataa aaaagactgc tctttcgagc agccagttaa aaaataatga
     3181 gtgtttattc ttgaaaaagc aacgcgctta tgaagcgcta ccaaaaattt atcatatttt
     3241 attaaaaata acaacccagt aaaaaatgac tggtaaaaat tcacaaagaa acggaaagaa
     3301 gcaaccgcag aaaatcaagc ttaaaaagag cttttgacct agaccaatcg aaaatcacaa
     3361 agtgagcgcc tgtatctatt gctacaggcg ctacttggca tagtgtacat tatgtcaaca
     3421 agaatttaat ataacatatt ttcctaatgc attctaacta taccacatta tcaaaaatat
     3481 aaattatctt tactaaataa aatattgaca agcctatacc ttttgtttta tgattttcac
     3541 aaagaaaacg ttttctatat atttttctgt atcaggagga aattctatga aaaaatttac
     3601 tttaggggta gctttgttaa ctattggggc agttgtttta ccgtcaacta ctatagttta
     3661 tgcttcagaa aattcccaag tggtatcatt aaacgaaaac aatgctactg aaaatgtagt
     3721 tattgagtac actgaagatg gtatggtcgt aactaaatat gaggatggtt atagtgcgga
     3781 agattttgca aattcttcag atatcatgac aagagctgca gttgcaagat ggggcaaaaa
     3841 ggaatataca aatattgctg taaccactgg agtagctgct aatgctatta atgctgcctt
     3901 ttgggcagga gggaaagcta gcacttctat gtttggtatc ccaggttggg caattggtgc
     3961 tttgttaaca ggtgcaagtt ggactaaaaa aggtgcttct ccagggaatg cagttgcaaa
     4021 agaatgggac aaaaatggta atggctggat tggattttat taccaaaggg gatatgatgc
     4081 agctggaaga gttgtagcta ctagatattc aacgttataa gttaaggagt gatgtttttg
     4141 atatctaaat cattaaaatc attaaaaaca tttactaaaa agaatccgca aatagctact
     4201 attcgtattt ttatatttgc tatagctgtt gctataattg ttaatatgct aagcggaggg
     4261 caattataca aatctggttt atttttagtg ttaatcttag ttgtcttaga cataataaag
     4321 tctaaaaaaa aataaatcga tacattttag aagaataggg ttgtttgaat attacaaagc
     4381 aacaatttca ccttcggtga aataagcgaa actttacaaa aagtggctag caaatgctag
     4441 cctttttttg tattgtggag cgtggatttt gagggggatt caagggggag cttgcgctcc
     4501 tttgacaagc ggttatttgc accaaatacg gaggtatttg gctagcaaat atagagcttg
     4561 ccaaaccctt ttagtgagct ttactcattg taccttttta ggtacaatgg tattgcgaac
     4621 gatacgtccg taggacgtac tgaaagggtg ggacttatga gcgaacaaca tcaaaatttg
     4681 gctagcgatc attctaaaaa atatacctat cgatccgagc caaaacaaat cagttttcga
     4741 gtgagcgaat ccgaatttgc aaagctgaag cagtcagctg aagctttgca aatgagtgtg
     4801 ccggctttcg tgaaagccaa ggcacaaaac gcgcgtctgg tgacaccgaa agtggcgcca
     4861 gacattgccc aggcaatcgc gcgcgattta gccaaagctg gagggaatat caatcaaatt
     4921 gccaagtggt gcaatacaca ccaacacgac gttgctcctg atgatgctca acgtttatcc
     4981 gaaaacctaa aaatcatgca aaaggagcta caaaagatat ggcaacagtt aaagtaagtc
     5041 gaaccacttc atgtagccga gcaatcaatt acgc
//
LOCUS       DAZULR010000105         4944 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.111, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000105 DAZULR010000000
VERSION     DAZULR010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4944
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.111"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(38..418)
                     /locus_tag="ACG8ZV_002722"
     CDS             complement(38..418)
                     /locus_tag="ACG8ZV_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HFS4997974.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(868..1155)
                     /locus_tag="ACG8ZV_002723"
     CDS             complement(868..1155)
                     /locus_tag="ACG8ZV_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFS4997975.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(1175..1399)
                     /locus_tag="ACG8ZV_002724"
     CDS             complement(1175..1399)
                     /locus_tag="ACG8ZV_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HFS4997976.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(1854..2024)
                     /locus_tag="ACG8ZV_002725"
     CDS             complement(1854..2024)
                     /locus_tag="ACG8ZV_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997977.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(2039..2572)
                     /locus_tag="ACG8ZV_002726"
     CDS             complement(2039..2572)
                     /locus_tag="ACG8ZV_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HFS4997978.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(2593..3537)
                     /locus_tag="ACG8ZV_002727"
     CDS             complement(2593..3537)
                     /locus_tag="ACG8ZV_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HFS4997979.1"
                     /translation="MANEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMREKGDKTVR
                     FTFDQLKDLSNYKATANVRFVEDLKATYEKILSLRFGRRSESGLSYDMFVMFTEFKIN
                     GDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQFNELQSGYAKTMFRLLKQYRTKGFA
                     YFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKADDFNKHAPTKEDQNKALALADKQKEYEEPATTINEKIKQKKRELELL
                     QQIKQLEKEKKALEKQTESALSEKEKKSLLSDLDNLFQ"
     gene            4174..4260
                     /locus_tag="ACG8ZV_002728"
     CDS             4174..4260
                     /locus_tag="ACG8ZV_002728"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HFS4997980.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(4381..>4944)
                     /locus_tag="ACG8ZV_002729"
     CDS             complement(4381..>4944)
                     /locus_tag="ACG8ZV_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997981.1"
                     /translation="LPGVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDK
                     KKKEQVLTQKMEEFTTCYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDN
                     YERTKKDVQYFKDTQTEEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATN
                     IQNPTKKETALNYLKSVKEWLDQQQQN"
BASE COUNT         1349 a          933 c          802 g         1860 t
ORIGIN      
        1 gcgtaattga tcgctcggct acaagaagtg gttcggctta ctttaactgt tgccatatct
       61 tttgtagctc cttttgcatg atttttaggt tttcggataa gcgttgggcg tcgccaggat
      121 caacgtcgtg ttggtgtgtg ttgcaccact tggcaatttg attgatattc ccgccagctt
      181 tggctaaatc gcgcgcgatt gcctgagcaa tgtctggcgc cactttcggt gtcaccagac
      241 gcgcgttttg tgccttggct ttcacgaaag ccggcacact catttgcaaa gcttcagctg
      301 actgcttcag ctttgcaaat tcggattcgc tcactcgaaa actgatttgt tttggctcgg
      361 atcgataggt atatttttta gaatgattgc tagccaaata ttgattttgt tcgctcataa
      421 gtcccaccct ttcagtacgt cctacggacg tatcgttcgc aataccattg tacctaaaaa
      481 ggtacaataa gtaaagctca ctaaagctca ctaaagggct tggcaagctc tatatttgct
      541 agccaaatac ctacgtattt ggtgcaaata accgcttgtc aaaggggcgc aagctccccc
      601 ttgaatcccc ctccccccca ctctccacaa tacaaaaaag actagcaaat gctagccact
      661 ttttgtaaag tttcgcttgt ttcaccttcg gtgaaattgt tgcaaatcaa taattaggta
      721 gagctacatt tttttcgttg ttcaaagatt cttatgccat ttactattaa taaatctata
      781 aatatgataa tttttcggct ctataattta tgggactgat gaatcagaat tgattcttca
      841 gtcccatttt cattttattc caaagaatta actccaaata ccaatagaag cccatcctct
      901 atatacttga gattccttac taacaatttc ttgtaattct attaaagatt taggtaatcc
      961 aaatttatgt tttaaaatat atcttccaag aaaactactt aatttcatac taacttcacc
     1021 aacacttttt ccctcactga tttctttaga ataaagaaag agcttttctt ttaagtcagg
     1081 atagtcatct atagttgctt cattgtatac tttactaatt gcatttaaaa gtttttcttc
     1141 tttagtaaaa tccattataa taacctccct accactacct tctaggtgcc catggaccat
     1201 gattaaccca accattaaca ataatttttc caatttctcc tttagcttga ttccaatcta
     1261 cccaacattt ttctttgtta caataaagac catttccata gtaagtagct gcatcaactt
     1321 ttattcctgt accgatgcca gctagacaag ttcctaatat tcctagaata acacaatgtt
     1381 ttaatacttt ctttttcatg attgtttttc cttttcgttt ttttaaaatt gcttgttata
     1441 ttaaataatc ttagtaattt tattatataa cattttatta tataacaatg attaacgtca
     1501 taaaaagtag ttttgaattc ataatcgttt aaataaaatt ataagatcag ttatttaaac
     1561 agctagtaga cataatgtgt atactaccaa gtaacgcctg taccaaggga tccaggcgct
     1621 gattttgtga atttttattg gtctaggtta aaagctcttt ttaaggcttg gttttctgcg
     1681 gttgtttctt tctaattctt tgtgaatatt gatcggtcat tttttaaata cttgttattt
     1741 ttgtttgtgt ttgttatgct ttttacatat ctcatattca tttattattc ttttctaagg
     1801 ttaataatag gataatctct ttcagaaaga ctgctcgtac gagcagtctt ttcttattta
     1861 tcaagttttt ctacaaatac ttcctcattt tgactgttgt agtaattagg attgagtttt
     1921 agttcccctt ttttatttcc tttgttggcc actgataata acattgggct aaagcttaat
     1981 attcctagta ggatagaacc gaatagcaag tgtttttttg tcataagtat ttccttcttc
     2041 atttccatag ctgccaccat tttttccaat tctttgtttg ttcgtccatt gtttctgttg
     2101 cttcagaaag agtcgttgaa ctattctctg aagactcttc cgtataagtc aactgcagtt
     2161 gctcctgaag tttttcgatt tgttggttgg cttgcagggt gagttgttgt tgctggtcga
     2221 gtagtttttg tatatgagaa ttattttgct ctttgagggc aagttgttct cgtaaaaatt
     2281 cattttcttc acgcaactga tctagcaact tgtttgcaac cacgtttttg tttggtatat
     2341 aagcattttt atcgttgttt tgttcatgtt tatgcaactt atctagcaac ctttgattgt
     2401 ctaagttgcg agcaagttgc aatactccag aacgcaatac aaccttataa ccacgctcat
     2461 ttttagctat catggaagaa tctaattttt ggatatgttt cgatattgct tgcctactca
     2521 tcttaaaaag atctgacaat tcctttattg taaaggtttc ttgtggttgc atactggttg
     2581 cctcctaggt tgctactgga ataaattatc taaatcagat aataaacttt ttttctcttt
     2641 ttccgaaagt gcggactctg tttgtttttc aagagctttt ttctcttttt ctagttgttt
     2701 gatttgttgg aggagttcaa gttctcgttt cttctgtttg attttttcgt taattgttgt
     2761 agcgggttct tcgtattctt tttgtttatc agctaaagcc aatgctttat tttggtcttc
     2821 tttggttggt gcatgtttgt taaagtcgtc tgcttttttg atctcaggtt tgaacgtaaa
     2881 ttgatagcca ataacaggtt ttccccgtcc ttttccgtat ttctttttga ttgttagtcc
     2941 tttgaagatt gcagttagtt cttgacgtat aggttttata actcgtttat ctatatcagg
     3001 ttgcttataa cttttaggaa tatctaataa ttcaagaaag tcttctttgg agaaatatgc
     3061 gaaacctttg gttctgtatt gctttaacag acgaaacata gtctttgcat agccactttg
     3121 tagctcgttg aattgttgta aagaatagcg tacccactcg tctaaattat ttaacaaagg
     3181 cagtgctttt tcgtaaattc gtatatctac gtaaggattt tctacgtccc cgttgatttt
     3241 aaattctgta aacattacaa acatatcgta agaaagccca gactcacttc tacgaccaaa
     3301 gcgtaaagat aagatttttt cataagttgc ttttaaatct tctacaaatc gtacatttgc
     3361 agttgctttg tagttactta aatcttttag ttggtcaaac gtaaaacgaa ctgtcttatc
     3421 ccctttttca cgcattctag acacgatgga aaaaaacaaa ttcatttcaa ccggtgtaaa
     3481 ttttcttaaa ggaattgtat ttaattcatg gtggtatttt acaatctcat tagccatata
     3541 atcacctcaa tccaattatg aatgacattt tttaaatgtc aagacattca tatttgacgt
     3601 tcaaacagac aaaatgtcct tcataaacag acaaaatgtc cttcataaac agacaaaatg
     3661 tccttcataa acagacaaaa tgtccttcat aacattctgt atccattggt agagtaagga
     3721 cacagcttac ggtaaagagg tttaaaaaga ggtttaaaaa gagatataaa aagagggggg
     3781 ctaattttcc cgcctaaaaa ccacttcttt tttctttaaa caggttcgcg catttttcaa
     3841 aactgccaat ccaaaacctt gcttcctacg gtcgccaaaa aggtgtgatc gctacgctct
     3901 cacattgtac tgcgcagtcg cctaaaggct cctttgctaa aaacatgttg gtaaagaggc
     3961 ctttgagcgg ttctgaatgc ttatctaagc cgttttaaga cagtcttgga taaaaatcct
     4021 tatctagctt taaagcgcct tacaggcggt cagggcaagc cctaacaacc ctaaaataag
     4081 cgatacttaa aaacaccaca caagtttaat tttttaagat ataataactt gtcgcctatc
     4141 cgacagtctt gcgactggaa ggaggtgtat ctaatgtttg aattgttcat ttgccccctt
     4201 cttatagaag tttgtgtctc tttattcagt tattggttga ataaccgaaa caagaagtaa
     4261 aatcaataaa ggcgacatca acctgaaaaa aagccccaga gaatccgacc tctctggggc
     4321 tttcgtgtat ctaatgtttg atcatttgca tgtttagttt aacatgattg ccgatcaaat
     4381 tcaattttgc tgttgctgat ctaaccattc cttgacactt tttagataat ttaatgccgt
     4441 ttcttttttc gttggatttt gtatgttcgt tgcttgctga agcagtgctt tataacgttc
     4501 gtaggtaact gattgttgcc gttcttttcg ttcctgttca ctagttgaaa aagggattgt
     4561 atcactgaat aaattataac aagcttcttc tgtctgcgta tctttaaaat attgcacgtc
     4621 ttttttggtt cgctcatagt tgtcttgaac ctctttttgc tgtttttctg gcaagttttg
     4681 ataaagacga gtgagttttt ccatgttttt atccgtcaaa cgtttttctt gattcacaaa
     4741 aatatcgttc atttcctcat aacaagtggt aaactcttcc attttttgtg ttaacacttg
     4801 ctcctttttc tttttatcac atgctgcttc atacttttga gtgatatccc ctaataaaat
     4861 acttcttgaa atacgtttat ttccctctaa aacgccgaat aaaccactta aaacgattga
     4921 taatgtaaat ataacccctg gcaa
//
LOCUS       DAZULR010000106         4933 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.112, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000106 DAZULR010000000
VERSION     DAZULR010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4933
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.112"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            85..972
                     /locus_tag="ACG8ZV_002730"
     CDS             85..972
                     /locus_tag="ACG8ZV_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFS4997982.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1112..2038
                     /gene="cysK"
                     /locus_tag="ACG8ZV_002731"
     CDS             1112..2038
                     /gene="cysK"
                     /locus_tag="ACG8ZV_002731"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HFS4997983.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2274..2720
                     /locus_tag="ACG8ZV_002732"
     CDS             2274..2720
                     /locus_tag="ACG8ZV_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFS4997984.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2993..4345
                     /locus_tag="ACG8ZV_002733"
     CDS             2993..4345
                     /locus_tag="ACG8ZV_002733"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HFS4997985.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4516..4803
                     /locus_tag="ACG8ZV_002734"
     CDS             4516..4803
                     /locus_tag="ACG8ZV_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HFS4997986.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
BASE COUNT         1695 a          813 c         1030 g         1395 t
ORIGIN      
        1 aattaaaagt ataatttaat taattaagtt tgttttaaga agagaacttt ttattaagtt
       61 tttttatttt gaggaggaat ttgaatgcaa gagctgaaga cccgcagtgc ccggcaccat
      121 agacctaaaa gaaaaatggt gatcaataaa aaagcgattg ctcctttaat tggaacgagt
      181 cttttagttg ggccgatgat ggttacagcg gtaccgcaac atgttcatgc agatgaacaa
      241 ggatctcaaa cagtcgctga tcctcaagcg tttatcgatc aaatcggctg gtctgcgtca
      301 gaagttgctg caagtaatga cttgtatgct tcagtcatga tcgctcaagc gttgttggaa
      361 agtgcatatg gcacttccgg attagctagt gcgccaaatt ataatctatt cggtgtgaaa
      421 ggaagctata acggacaggt cgtttatatg gcaaccaaag aatatgtaaa cggacaatgg
      481 gtaacgatga atgagccatt ccgaaaatat tcttcttatt gggaatcctt ccaagaccat
      541 gcgaatgttc ttcgttcaac cagtttttcc acgggcgatt atcattatgc tggcgtgtgg
      601 aaaagcaata caacaagttt ttatgatgca acagcgtact tgacaggtcg ttatgctacc
      661 gatccaaatt atggggccaa attgaactca ttgattaata cttataattt aacccgtttt
      721 gatacgccat caacaggttc ggctacaaca accacaagta caacaacaac gactactacg
      781 acgacttcaa cgtcatcatc ttcaacaaca gatgtaaata caaataatgg tcagacatat
      841 acagtcgtgt caggtgatac gctatgggat attgcacaaa aatttggcat gtctgttgat
      901 gatctaatgg cgaaaaatgg catgtctatg tccagttatt ctttattagt tggtcaagaa
      961 ctaaacgttt gatttagata aaaaggcaaa gaaattacca tatatggtat atctttgtct
     1021 tttttttgct agtcaaagac gaatcactcg ccataaatga acagattgta ttatgataag
     1081 taagaagagc aaagacaagg aggaattgaa gatgacagct atctataact cagtcaccga
     1141 attgattggc aaaacgccaa tcgtcaaatt aaataaaatc gtaccagaag attcagcaga
     1201 tgtttttgta aagcttgagt tttttaatcc aggaggaagt gtaaaagatc gtattgcttt
     1261 aagtatgata gaaaaagcag aacacgatgg tctactgaaa ccaggtgata ctatcattga
     1321 acctacttct ggaaatacag gaatcggatt gtcgatggta ggagttgcaa aaggatataa
     1381 agtaatcatc gtgatgcctg agacgatgag tatcgaaaga cgtttattga tgaaagggta
     1441 cggcgcagag ttgattttga ctcctggtgc ggatggtatt tctggatcaa tcagagaagc
     1501 agaacgtttg gcaaaagaaa acggctactt tttaccatta caatttgaaa atgaagcaaa
     1561 tcctcttgtg catgagaaga cgactggtcc tgagatacat caagcatttg gagtaaatgg
     1621 cttggacgcg tttgttgcag gtatcggtac aggaggaacg atcactggcg ctggccgaga
     1681 attaaaacgt gtgtatccga aaatcgaatt aatcggggta gaaccagcag aatctgctat
     1741 tttagaaggg aaagaagcgg gacctcacaa aatccaagga atcggtacag gttttgttcc
     1801 taaaacactg gatacttctg tgtatgataa agtcctttct attagtggag acgaagcgat
     1861 ggaaacagct agagaagttg ggcgaaaaga agggatttta gtaggcatct catctggcgc
     1921 tgcaattgct gccgcgctaa aagtcgcaaa agaattagga aaaggcaaga aggtattagc
     1981 tgtggttccc gacaatggtg aacgttattt atctacagcc ctttaccaag agatataagg
     2041 cacttggttt ttctccagat aggtttatgt aaaaaacttt taaagatgaa aagaacacac
     2101 aaaaatttat gatgagaaaa attatttgaa tagagacgta gaatagtgaa cgcgactgtt
     2161 ttacgtcttt tttcattaaa atacaataaa attgaatttt cttttcatgt taagtggatt
     2221 ttaaaatgta aaaatagtat gataagacga gaataacaac gtggggtgtt tacatggaaa
     2281 ataagttagt cgaagaggtt atcgaaaagt taaaaaaaga gaacattcga atcacacctc
     2341 aacggtacgc ggttttagaa tatttgattg aacatcattc ccatccaacg gctgatgaga
     2401 tttataaagc acttgaacat cggtttccaa atatgagtgt tgcgactgtt tacaataacc
     2461 ttcgcttatt tacttcgatt ggatttgttc aagaaatgaa gtacggcgat gcttctagcc
     2521 gatttgattt cagttcaaag cgtcattatc atgtaatttg tgaaaactgc ggtaagattg
     2581 ttgattttca ttacccaggg cttgaagata tagaaatggc tgcaagcaga ctgactgatt
     2641 ttgagattaa tgaacatcgg ttggaattgt atggactctg tccggattgt aaagagtcag
     2701 caaaaaaggc gcaaatgtaa aaacagtttc tacaagtgtt atacctaaaa aaagctagct
     2761 gtgtaaaaaa aacgctagct tttttatttt tttgtctttt attcacaatc ttagatataa
     2821 aagtgaatat tattaaaata agaatcttgt agatattggg ttcttatgct tgaaaaggaa
     2881 tgaaactaca aacaaacctt tgtgaattca caagcattaa actgttgtat ccgttttatt
     2941 tctgttatag tagttttgtc gaaggacaaa atgttaatcg gagggaccat aaatgaaagt
     3001 agtagtaatt ggctgtactc atgcaggtac tgcagctgta aaaagtattt taaaaaatca
     3061 tccagaagca gaagtgacag tatatgaaag aaatgacaat atttctttct tatcttgcgg
     3121 tatcgcactt tatgtcggcg gagtagtaaa ggacccagca ggcttgttct actcaaatcc
     3181 tgaagaatta tcttcattag gagcaacagt taaaatggaa cacgatgtaa cagacgtcga
     3241 tacagaaaat aaaacagtaa cggcaaaaga tctgaaaaca ggagaaacag aaacggtttc
     3301 ttatgataaa ttagtgatga caactggttc atggcctatt atcccaccga ttagtggaat
     3361 cgatgcgaaa aatgtactcc tatgcaaaaa ctacaatcaa gcaaatgaaa ttattgcaca
     3421 agcgaaagaa gcaaaacgtg tagtaattgt tggtggtgga tatatcggta ttgaattagt
     3481 agaagctttt gtcgaatctg gaaaacaagt gacattgatt gatggattag atcgcatctt
     3541 gaataaatat ctagataaac cattcacaga tatcttagaa aaagaattga cagaccgcgg
     3601 tgttactctt gcgctaggcg aaaatgttac tgaatttatc acagatgaag aaggaaaagt
     3661 gaaacaagta gctacaccaa cagatacatt tgatacagat atggtcattt tatgtgtggg
     3721 cttccgtcca aatacaaaac tgatcgaagg aaaagtagat acactgccaa acggggcaat
     3781 caaagtgaat gaatacatgc agacaagtaa tccagacatt tttgcagctg gagactctgc
     3841 agtagtcaac tacaatccaa gtggcacgca aaactatatt cctttggcaa caaatgccgt
     3901 tcgtcaaggt ttgcttgtgg gaaataactt gacagatcat aaaatggcgt atcgtggtac
     3961 tcaaggaact tcaggacttt acctatttgg ctggacgatc ggttcgacag gtgtgaccaa
     4021 agaaagcgca actttgaacg atctagaagt ccaagcgact gtatttgaag ataattatcg
     4081 tccagagttc atgccaacta ctgaaaaagt aatgatggag ctagtctatg aaaaaggaac
     4141 gaatcgtatc gtaggtgctc agttcatgtc caaatacgac attacacaat cagcaaatac
     4201 catgtcttta gctgttcaaa ataaaatgac tgtagaagat ctcgcacttt cagatttctt
     4261 cttccaacca cattttgacc gcccatggaa ttacttgaac ctacttgcac aagcagcgct
     4321 aggcgaaatc gaaactgcac aataaagaaa aagggttgtg acacaatttt gtcacgaccc
     4381 tctgtctttt tttgtgaaaa gtacaattag ttgtctttct tcgaattttt tgtcacaata
     4441 agcagcaaag ataaagctgt tacataaaag aacaagcagc tttatttgat tttgaaaaga
     4501 aaggtgagaa agaagatgaa taaagaatat tttgtccaac aagatgcatt tttagaagat
     4561 tataaaagtg cttcgaagaa attaacgatc aatattgatg agttggcaga tcaagtactc
     4621 tctcagttga atgaaacgca agaggaatat tacacgatgc cagcaaatga cgccaaagat
     4681 aatgtttctc atcgttttcc tttcagtaga cgcatctact cagatgaaaa tgacggcaca
     4741 ttgaatacag agtacacata tgaaggtcag ccatatgtgc tagaaactga tgatgatctt
     4801 taaagacagt ttttgaaaag gccgctcatc cttaagtgat gacaaaaaat catcacaatt
     4861 accgatgact gtctctttac tatcttttaa tcagaaaaag gggttatgac aagctttgtc
     4921 aacccctttt ttt
//
LOCUS       DAZULR010000107         4722 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.114, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000107 DAZULR010000000
VERSION     DAZULR010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4722
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.114"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            51..746
                     /gene="vanR-A"
                     /locus_tag="ACG8ZV_002735"
     CDS             51..746
                     /gene="vanR-A"
                     /locus_tag="ACG8ZV_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-A"
                     /protein_id="HFS4997987.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            724..1878
                     /locus_tag="ACG8ZV_002736"
     CDS             724..1878
                     /locus_tag="ACG8ZV_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-A"
                     /protein_id="HFS4997988.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            2093..3061
                     /locus_tag="ACG8ZV_002737"
     CDS             2093..3061
                     /locus_tag="ACG8ZV_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HFS4997989.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            3054..4085
                     /gene="vanA"
                     /locus_tag="ACG8ZV_002738"
     CDS             3054..4085
                     /gene="vanA"
                     /locus_tag="ACG8ZV_002738"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HFS4997990.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            4091..4699
                     /locus_tag="ACG8ZV_002739"
     CDS             4091..4699
                     /locus_tag="ACG8ZV_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HFS4997991.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT         1456 a          907 c         1109 g         1250 t
ORIGIN      
        1 tataatctga taaattatta agggcaaact tatgtgaaag ggtgataact atgagcgata
       61 aaatacttat tgtggatgat gaacatgaaa ttgccgattt ggttgaatta tacttaaaaa
      121 acgagaatta tacggttttc aaatactata ccgccaaaga agcattggaa tgtatagaca
      181 agtctgagat tgaccttgcc atattggaca tcatgcttcc cggcacaagc ggccttacta
      241 tctgtcaaaa aataagggac aagcacacct atccgattat catgctgacc gggaaagata
      301 cagaggtaga taaaattaca gggttaacaa tcggcgcgga tgattatata acgaagccct
      361 ttcgcccact ggagttaatt gctcgggtaa aggcccagtt gcgccgatac aaaaaattca
      421 gtggagtaaa ggagcagaac gaaaatgtta tcgtccactc cggccttgtc attaatgtta
      481 acacccatga gtgttatctg aacgagaagc agttatccct tactcccacc gagttttcaa
      541 tactgcgaat cctctgtgaa aacaagggga atgtggttag ctccgagctg ctatttcatg
      601 agatatgggg cgacgaatat ttcagcaaga gcaacaacac catcaccgtg catatccggc
      661 atttgcgcga aaaaatgaac gacaccattg ataatccgaa atatataaaa acggtatggg
      721 gggttggtta taaaattgaa aaataaaaaa aacgactatt ccaaactaga acgaaaactt
      781 tacatgtata tcgttgcaat tgttgtggta gcaattgtat tcgtgttgta tattcgttca
      841 atgatccgag ggaaacttgg ggattggatc ttaagtattt tggaaaacaa atatgactta
      901 aatcacctgg acgcgatgaa attatatcaa tattccatac ggaacaatat agatatcttt
      961 atttatgtgg cgattgtcat tagtattctt attctatgtc gcgtcatgct ttcaaaattc
     1021 gcaaaatact ttgacgagat aaataccggc attgatgtac ttattcagaa cgaagataaa
     1081 caaattgagc tttctgcgga aatggatgtt atggaacaaa agctcaacac attaaaacgg
     1141 actctggaaa agcgagagca ggatgcaaag ctggccgaac aaagaaaaaa tgacgttgtt
     1201 atgtacttgg cgcacgatat taaaacgccc cttacatcca ttatcggtta tttgagcctg
     1261 cttgacgagg ctccagacat gccggtagat caaaaggcaa agtatgtgca tatcacgttg
     1321 gacaaagcgt atcgactcga acagctaatc gacgagtttt ttgagattac acggtataac
     1381 ctacaaacga taacgctaac aaaaacgcac atagacctat actatatgct ggtgcagatg
     1441 accgatgaat tttatcctca gctttccgca catggaaaac aggcggttat tcacgccccc
     1501 gaggatctga ccgtgtccgg cgaccctgat aaactcgcga gagtctttaa caacattttg
     1561 aaaaacgccg ctgcatacag tgaggataac agcatcattg acattaccgc gggcctctcc
     1621 ggggatgtgg tgtcaatcga attcaagaac actggaagca tcccaaaaga taagctagct
     1681 gccatatttg aaaagttcta taggctggac aatgctcgtt cttccgatac gggtggcgcg
     1741 ggacttggat tggcgattgc aaaagaaatt attgttcagc atggagggca gatttacgcg
     1801 gaaagcaatg ataactatac gacgtttagg gtagagcttc cagcgatgcc agacttggtt
     1861 gataaaagga ggtcctaaga gatgtatata attttttagg aaaatctcaa ggttatcttt
     1921 actttttctt aggaaattaa caatttaata ttaagaaacg gctcgttctt acacggtaga
     1981 cttaataccg taagaacgag ccgttttcgt tcttcagaga aagatttgac aagattacca
     2041 ttggcatccc cgttttattt ggtgcctttc acagaaaggg ttggtcttaa ttatgaataa
     2101 catcggcatt actgtttatg gatgtgagca ggatgaggca gatgcattcc atgctctttc
     2161 gcctcgcttt ggcgttatgg caacgataat taacgccaac gtgtcggaat ccaacgccaa
     2221 atccgcgcct ttcaatcaat gtatcagtgt gggacataaa tcagagattt ccgcctctat
     2281 tcttcttgcg ctgaagagag ccggtgtgaa atatatttct acccgaagca tcggctgcaa
     2341 tcatatagat acaactgctg ctaagagaat gggcatcact gtcgacaatg tggcgtactc
     2401 gccggatagc gttgccgatt atactatgat gctaattctt atggcagtac gcaacgtaaa
     2461 atcgattgtg cgctctgtgg aaaaacatga tttcaggttg gacagcgacc gtggcaaggt
     2521 actcagcgac atgacagttg gtgtggtggg aacgggccag ataggcaaag cggttattga
     2581 gcggctgcga ggatttggat gtaaagtgtt ggcttatagt cgcagccgaa gtatagaggt
     2641 aaactatgta ccgtttgatg agttgctgca aaatagcgat atcgttacgc ttcatgtgcc
     2701 gctcaatacg gatacgcact atattatcag ccacgaacaa atacagagaa tgaagcaagg
     2761 agcatttctt atcaatactg ggcgcggtcc acttgtagat acctatgagt tggttaaagc
     2821 attagaaaac gggaaactgg gcggtgccgc attggatgta ttggaaggag aggaagagtt
     2881 tttctactct gattgcaccc aaaaaccaat tgataatcaa tttttactta aacttcaaag
     2941 aatgcctaac gtgataatca caccgcatac ggcctattat accgagcaag cgttgcgtga
     3001 taccgttgaa aaaaccatta aaaactgttt ggattttgaa aggagacagg agcatgaata
     3061 gaataaaagt tgcaatactg tttgggggtt gctcagagga gcatgacgta tcggtaaaat
     3121 ctgcaataga gatagccgct aacattaata aagaaaaata cgagccgtta tacattggaa
     3181 ttacgaaatc tggtgtatgg aaaatgtgcg aaaaaccttg cgcggaatgg gaaaacgaca
     3241 attgctattc agctgtactc tcgccggata aaaaaatgca cggattactt gttaaaaaga
     3301 accatgaata tgaaatcaac catgttgatg tagcattttc agctttgcat ggcaagtcag
     3361 gtgaagatgg atccatacaa ggtctgtttg aattgtccgg tatccctttt gtaggctgcg
     3421 atattcaaag ctcagcaatt tgtatggaca aatcgttgac atacatcgtt gcgaaaaatg
     3481 ctgggatagc tactcccgcc ttttgggtta ttaataaaga tgataggccg gtggcagcta
     3541 cgtttaccta tcctgttttt gttaagccgg cgcgttcagg ctcatccttc ggtgtgaaaa
     3601 aagtcaatag cgcggacgaa ttggactacg caattgaatc ggcaagacaa tatgacagca
     3661 aaatcttaat tgagcaggct gtttcgggct gtgaggtcgg ttgtgcggta ttgggaaaca
     3721 gtgccgcgtt agttgttggc gaggtggacc aaatcaggct gcagtacgga atctttcgta
     3781 ttcatcagga agtcgagccg gaaaaaggct ctgaaaacgc agttataacc gttcccgcag
     3841 acctttcagc agaggagcga ggacggatac aggaaacggc aaaaaaaata tataaagcgc
     3901 tcggctgtag aggtctagcc cgtgtggata tgtttttaca agataacggc cgcattgtac
     3961 tgaacgaagt caatactctg cccggtttca cgtcatacag tcgttatccc cgtatgatgg
     4021 ccgctgcagg tattgcactt cccgaactga ttgaccgctt gatcgtatta gcgttaaagg
     4081 ggtgataagc atggaaatag gatttacttt tttagatgaa atagtacacg gtgttcgttg
     4141 ggacgctaaa tatgccactt gggataattt caccggaaaa ccggttgacg gttatgaagt
     4201 aaatcgcatt gtagggacat acgagttggc tgaatcgctt ttgaaggcaa aagaactggc
     4261 tgctacccaa gggtacggat tgcttctatg ggacggttac cgtcctaagc gtgctgtaaa
     4321 ctgttttatg caatgggctg cacagccgga aaataacctg acaaaggaaa gttattatcc
     4381 caatattgac cgaactgaga tgatttcaaa aggatacgtg gcttcaaaat caagccatag
     4441 ccgcggcagt gccattgatc ttacgcttta tcgattagac acgggtgagc ttgtaccaat
     4501 ggggagccga tttgatttta tggatgaacg ctctcatcat gcggcaaatg gaatatcatg
     4561 caatgaagcg caaaatcgca gacgtttgcg ctccatcatg gaaaacagtg ggtttgaagc
     4621 atatagcctc gaatggtggc actatgtatt aagagacgaa ccatacccca atagctattt
     4681 tgatttcccc gttaaataaa cttttaaccg ttgcacggac aa
//
LOCUS       DAZULR010000108         4608 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.115, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000108 DAZULR010000000
VERSION     DAZULR010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4608
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.115"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..505)
                     /locus_tag="ACG8ZV_002740"
     CDS             complement(<1..505)
                     /locus_tag="ACG8ZV_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFS4997992.1"
                     /translation="MDEKTELTVKYQNELNLVPLKNFNAKQMDLFFALCARMKDRGLK
                     KVRFSFEELKELSDYKMTATKAFVGDLEKLYKDMLNLTYRTEDEDSIRYFVLFTGFEI
                     NKTKKFVEVSVNPDLEYIINGLTAEFSRFELSAFTSLRSTYAKTLFRLLMQYRSTGYY
                     VVRIEEFR"
     gene            1167..1253
                     /locus_tag="ACG8ZV_002741"
     CDS             1167..1253
                     /locus_tag="ACG8ZV_002741"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HFS4997993.1"
                     /translation="MFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            1953..2249
                     /locus_tag="ACG8ZV_002742"
     CDS             1953..2249
                     /locus_tag="ACG8ZV_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997994.1"
                     /translation="MNVKIRDLDPKFISEIDRRCVELSNRTGNKWSRNDYLKLLVEND
                     FDRPLMEYKQEKFDQLLEKFSEIQSYNTKILEEYVSQNNRIIEILIEQNRGSEL"
     gene            2251..2673
                     /locus_tag="ACG8ZV_002743"
     CDS             2251..2673
                     /locus_tag="ACG8ZV_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997995.1"
                     /translation="MAKVIDKHIYFHQTHIDVLDETISTHAEVKNYSEAVRFLCMNYD
                     PEVEKKVNSNQAKLNGMSKEISILTEMVSEFADLHLKDTGILIGKNSTVYQEAKERVE
                     GKIKSNQTKKYSPQLKKPVNESVHARVDPFDPTKILKR"
     gene            2692..4284
                     /gene="mobP2"
                     /locus_tag="ACG8ZV_002744"
     CDS             2692..4284
                     /gene="mobP2"
                     /locus_tag="ACG8ZV_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobP2 family relaxase"
                     /protein_id="HFS4997996.1"
                     /translation="MTQSPSVILTCQFTLPNKKSFSTYIDYITREQALEEKERRTPEE
                     EQELQRIKNALEEFYIPEGETFSESKTGKEFSETSNEAQSLMEHGINFDKLEEQDFTN
                     YLSYMTRHYALEQKKELTQSEQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSIASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVVSHDHSYLEKIGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEVENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPDKRSEWNYGDEKRTKLSPYTREKLDELTKYVLTKEPEYQEYIQ
                     ISKALKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKRQDSQIKPLIESVD
                     QMQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            4305..>4608
                     /locus_tag="ACG8ZV_002745"
     CDS             4305..>4608
                     /locus_tag="ACG8ZV_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4997997.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLRNEQF
                     DPNQFLVVEYPATGVYCCNHVNGEKYFIIQEYEGKLAPYYTTWEMNEEGINNFPCKS"
BASE COUNT         1707 a          772 c          838 g         1291 t
ORIGIN      
        1 tcctaaactc ttcaatacga actacataat aaccagtaga acggtactgc ataagcagtc
       61 ggaatagagt ttttgcatac gtagaacgca acgacgtgaa agcagataat tcaaatctac
      121 taaattcagc tgttaaacca ttaataatat attctaggtc cggattaaca ctgacttcaa
      181 caaacttttt tgttttattg atttcaaaac cagtaaacaa aacaaagtag cgaatagaat
      241 cctcatcttc agtacggtaa gtaagattaa gcatatcttt atagagcttt tctaaatcac
      301 cgacaaaggc ttttgtagca gtcatcttat aatcacttaa ctcttttaat tcctcgaaag
      361 aaaatctaac ttttttcaaa ccacgatctt tcatacgagc gcataatgca aaaaataaat
      421 ccatctgctt agcattgaaa tttttcagcg gtactaaatt caattcattt tgatatttga
      481 ctgttaattc cgttttttca tccattcctt tcttcccccc ttacaaataa ataataacct
      541 ttaacaacca actcgtaaat aggttggttg ttattataca aaaggatatt agtactcaga
      601 taaaaagttg ttagtactca gataaaaagt tgttagtact cagataaaaa gttgttagta
      661 ctcagataaa aagttgttag tacccttctg tatccgttgg gagagtaagg ctcaactgcc
      721 ccctaaaaag ggttctaaaa aatctttaaa aaataaataa aataaacgcg cgcgcgcgag
      781 caaaatttcc cgccaaaaaa tcacccactt tttaaaataa acaggttcgc gcatgatatt
      841 aaactgccaa tctagctccc tatggtcgct gtaagaagga gtgatcgcta cgctctcaca
      901 ttttacttgc agcagtcgcc tttaggctcc ttcgccaaaa ataattcatt agggactcct
      961 ttgtggcgtc ctgagagctc gtctaagccg ttctaagaca agattcgata aaaactatgt
     1021 ccttcgttct aaagcgcctt acaggcggtc agggcaagcc ctaacaaccc caaggcaata
     1081 aaaaacttag gcttattttt gcttttttat tgtataattg attgtcgcct atccgacagt
     1141 cttgcgactg gaaggaggtg tgtttcgtgt tcactaactt tatttgctcc cttcttgttg
     1201 ggcttttaag cgctttgttc agttactggt tgaataaccg aaacaagaag taaaacttaa
     1261 ttaaggcgac tcagcccaca aaaaaagccc cagagaatcc gacctctctg gggatttcgt
     1321 gtgtttcgtg ttcacttatt tgcaatcaaa ttataacaga aataaatatt tatttcaaaa
     1381 atatcctaca aaagtctaaa atccgtaatt atttcttata tgcaacattt acaaataaag
     1441 tcgctctgag agctcgtatt tttcgattta agacgtttta tttagttttt ggtgtatttc
     1501 attggtccaa gctaaaaaac tcttagaagc gattttagag ccatttaaac ccacttaatt
     1561 atattctcca tgaaattcgc tccatgcgtc aaaagctgcg tctgaaattc cgccgtcttc
     1621 gttcactagt tgcattaatt tttccaacga tcgttttctt tcgggtgtca tatttttata
     1681 ttccaacaat ttttcgtctg ttaaatttgg ttatcgatta cacgtgcagc actccccccc
     1741 gaattttaaa gagcataagg aaacgtgacc ccacttttaa aaaaagtggt tggataggct
     1801 gtgcctatca cgtttctgaa aaaaataaat gaccccaaaa taccaatata taggatagta
     1861 caaggatagc aaaggatagt aaaaggatag aggtaggata gcgaaaagga taggatcctt
     1921 ttcactatcc tatattatat tggaggatat ttatgaatgt taaaattaga gatttagatc
     1981 caaaattcat ttctgaaatt gatcgaagat gcgttgaact aagtaatcgt acaggaaata
     2041 aatggagtcg taatgattat ttaaagctac tcgttgaaaa tgattttgat cgtcctttga
     2101 tggaatacaa acaagaaaag tttgaccagt tattagaaaa gttttcagaa attcaaagtt
     2161 ataacacaaa gatattagaa gaatatgtta gccaaaataa tcgtattata gaaatcttga
     2221 ttgagcaaaa tagaggaagt gaactttgat atggcaaagg ttatagacaa acacatttac
     2281 tttcaccaaa cacatatcga tgtattggat gaaactattt ctactcatgc agaggttaaa
     2341 aactatagtg aagctgttcg ctttttatgt atgaactatg atccagaagt ggagaaaaaa
     2401 gtaaattcca atcaagcaaa gttgaatgga atgagtaaag aaatttctat tttaaccgaa
     2461 atggtttcag aatttgcgga tcttcatttg aaagatacag gaatattaat tggtaaaaat
     2521 tcaactgttt atcaagaagc aaaagaacga gtggaaggaa aaattaaatc caatcaaaca
     2581 aaaaaatatt cccctcagtt gaagaaacct gtgaatgaat ctgttcatgc cagagtagat
     2641 ccatttgatc caacgaagat tctaaaaaga taaaaatgaa ggaggataat aatgactcaa
     2701 tcgccttcag ttattctcac ttgtcaattt actttgccga ataaaaagtc attttctact
     2761 tatattgact atattacaag ggaacaggct cttgaagaaa aggaacgacg tacgcccgaa
     2821 gaagaacagg aacttcaacg aatcaagaat gctttagagg agttttatat tcctgaagga
     2881 gaaacttttt cggagagtaa gacgggtaaa gaattcagtg aaacgtcgaa tgaagctcaa
     2941 tcgttgatgg aacatggaat caattttgac aagttagagg aacaagattt taccaattat
     3001 ctttcttata tgacacgtca ctatgcgtta gaacaaaaga aagaactgac gcaaagtgaa
     3061 caaaaagaat accaacgctt gaaccaagca atgaaaaaat atcaaacaga accccataaa
     3121 aaagcttcag gaaatcttcc tggagttttt tctatagctt cagacgaagt gaaaggaagt
     3181 gatctgaagg agattaagca aatcttccaa agaggacaac aaaaaggctc aatcatttat
     3241 caagatgttg tttctcatga tcattcgtat cttgaaaaaa taggattgta tgatcccaaa
     3301 acagatactt tagatgaaga agggttaaaa gcagctggaa gaaaaatgat ggagacatta
     3361 ttcgagaaag aacaattgaa tgaaacaggt tactggatgg caacgattca ccgtaacact
     3421 aaacatatcc atattcattt tgcagttgtt gaaaaagaaa atacgcgtaa accttacacg
     3481 gaggttgaaa atggtgtgag ttatatcgta ccgaaaggta agagaagaca agcaacatta
     3541 gacgcaatga agaccaatta tgtacatgag ttagaacgtt tttcttatga aaaggatcga
     3601 atgattggta tggagaaacg aaatttattg acgcggaaaa gtgatttgcg taacacctta
     3661 acaaaagtgg taaaagagcc agcgcgttac gatcgacacg cgatgaactt attaaatgaa
     3721 gtatataaaa ccctacctga caaacgttcg gaatggaatt acggggatga aaaacgaacc
     3781 aaactttcac catacacaag agagaaactc gatgagttaa ccaaatatgt tttaacaaaa
     3841 gaacctgaat atcaagaata tatacagatt tcaaaagcat tgaaagaaga agcaaaaagt
     3901 ctttatgggg aaagcaagag agaatcaaag gatgcagaga aaaatgctct ctttgattta
     3961 aaaaagcgca caggaaatgc catcctaaca gagctgaaga gacaggatag tcaaataaaa
     4021 ccattaatag aaagtgttga tcagatgcaa tctatttaca atgaacgatc ctttcgaacg
     4081 cttaaacaat tgccaacgaa tgaatacaaa tatagttacg aagaattcat gaagcgcagg
     4141 aaacaattcc aacaaagagt tgtcacgcag cggagtttgc gtcaattaaa tcgaacgatt
     4201 aatgcccatg aagaaaaata ccacgcaagt aaagcatacg aagagcaaca acgaagaatt
     4261 caaatggaac aagaaagaca gtaaagacag taggaggaat agcaatgaaa caatatttag
     4321 atcaatggaa agttatagaa ggatcattaa gagaagaacg aatcgaacaa cttcctgatt
     4381 gtttagaaaa agagcatttg ttccagataa gagaaatgtt gagaaacgaa cagtttgatc
     4441 caaatcaatt tttagtcgtt gagtacccag ctactggtgt gtattgttgt aatcatgtga
     4501 atggtgaaaa atattttatc attcaagaat atgagggcaa gttagcacct tattatacta
     4561 cttgggaaat gaatgaagag ggaatcaata actttccatg taaaagca
//
LOCUS       DAZULR010000109         4465 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.116, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000109 DAZULR010000000
VERSION     DAZULR010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4465
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.116"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            574..1008
                     /gene="bacA"
                     /locus_tag="ACG8ZV_002746"
     CDS             574..1008
                     /gene="bacA"
                     /locus_tag="ACG8ZV_002746"
                     /inference="COORDINATES: protein motif:HMM:NF041453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin 51 precursor BacA"
                     /protein_id="HFS4997998.1"
                     /translation="MKNKIIKIITCLFLFGMIVGASTPLNLFPFSARGIKVEAASSRY
                     NHNHRGFTCYKMNYYVTNKMCRDLKKNYNKLKTPAQIASFIPIGGVGTWVITNAFSSA
                     VDAMNVFVRAANQGKGVQLTYNAHFSNTTSYQYNDYARYVIK"
     gene            2298..3221
                     /locus_tag="ACG8ZV_002747"
     CDS             2298..3221
                     /locus_tag="ACG8ZV_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFS4997999.1"
                     /translation="MANEIVKYENRLNHIPLRKFNSREMNLFFSIASRVREKGVDEII
                     FSFHDLKKLSGYTERGEQFIKDLSSTYDKLLSINAWNDDGNTLTKFVAFTKYSIIRDK
                     QLVIISVNPEFKGLFNQLKNWTRFNLEQFTNLDSTYSKTMFRLLKQYRTQGWTEFSKE
                     KFFDLLDIPKSYWNSPSNIDKFILRPIKEELTPLFKGLTIRKKYGKGRGKPVIGYRFT
                     WKAEINHADDFSKGKQEDLRIKLFNIDHNGELTREEKWRAKDRILNLPLGTHEADFKQ
                     QQQTEEKQAEKRELSNKLKQDLLGNLQNLFD"
     gene            3237..3776
                     /locus_tag="ACG8ZV_002748"
     CDS             3237..3776
                     /locus_tag="ACG8ZV_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HFS4998000.1"
                     /translation="MADKTIKELAEELGVSKTAINKKVSDKNRKLWFAKNGNKFVINE
                     TGQKAIKSMFLVDNANLNRKLVGEKSKTKNHKNTNQVSELKLLSFLEKQLNRKDIQLQ
                     EKDNQIKQMQKLLDQQQQLTLQANQQIENLQEQLHLTYTEETPTTESTAFSEKKADNT
                     QPLIEKKWWQIWKSNRTNL"
BASE COUNT         1667 a          673 c          757 g         1368 t
ORIGIN      
        1 aaaaaaaact gtgttggtac tgggttctat ttctctagga atattaggtt ttagccccat
       61 gctattatcc gtaattggaa aaaacaattc caacggagaa cttaaattaa attcaaatta
      121 ttacaacagt cctaacgaag aattgtttgt aaaagagacg gataaataat aaaaaagact
      181 gctctttcga gcagccagtt aaaaaataat gagtgtttat tcttgaaaaa gcaacgcgct
      241 tatgaagcgc taccaaaaat ttatcatatt ttatgaaaaa taacacccca gtaaaaaatg
      301 actggtaaaa attcacaaag aaacggaaag aagcaactgc agaaaatcaa gccttaaaaa
      361 gagcttttga cttagaccaa tcgaaaatca caaagtgagc ccctgtatcc cttggtagag
      421 aggctacttg gcatagtata cattatgtct actaaccttt aaaataacac gttttataaa
      481 ataaaccctc ttgacaatat ttaattttct gattattcta aatatataca gaaagcgctt
      541 tcctaggatt ttatatctaa ggaggaagta acaatgaaaa ataaaattat taaaattatt
      601 acttgtctat ttttgttcgg tatgattgtt ggagcaagta ctccgttaaa tctgtttcct
      661 tttagtgcta gaggtataaa agtggaagct gcaagttcac gatataatca taatcatcgt
      721 ggatttactt gctataaaat gaactattat gttactaata aaatgtgtag agatttgaaa
      781 aaaaattata ataagctaaa gactcctgct caaattgcat cttttattcc tattggtgga
      841 gttggaacat gggttattac aaatgctttt agtagtgctg ttgatgcaat gaatgtcttt
      901 gtaagagctg caaatcaagg aaaaggtgta caattaacat ataatgctca ctttagcaat
      961 acaacatcat atcaatacaa tgattacgct cgttatgtaa taaaataatc agaaagtgaa
     1021 actatctcat gaataaaaag attttagctg taattatttc aataatagtt ttaatcacta
     1081 tgttcttcat atttaggcta attttcaata taagcttaca aaaaagtatt ctttatctaa
     1141 ttcctatagc atttatctta gcaattttta gaagtattta cggaaataaa aactctaaat
     1201 agctaaaaat aaatcatact aaattttaca aaaagtggct agcattttct agccactttt
     1261 tgtattgtgg agcgtgggtt ttgaggggga ttcaaggggg agcttgcgcc cctttgacaa
     1321 gcggttattt gcaccaaata cggaggtatt tggctagcaa atatagagct tgccaaaccc
     1381 ttttagtgag ttttgtagaa agtaccttta aaggtacttt cacattacga acgatacgtc
     1441 cgtaggacgt actgaaaggg tgggacttat gagcaaatta atgcaaaatt tggctagcaa
     1501 aaaagctaaa aaatatatgc taataatcga gcgaaataaa cactttttca agtgagcgaa
     1561 tccgccatga caaagctgaa gcagtttatt tcagctttgt catggcgtgt gccgactttt
     1621 ttaaaagtct aggcacacga gcaaatatct ttatcaagct ctaatttgcg ttttaagacg
     1681 tttgaaacgc ctaagtatat aaatatataa gaataggttt aagagtgctt aaatcgaatt
     1741 ttagagggca tttagacaat tttagggttg ttagggcttg ccctgaccgc ctgtaaggcg
     1801 ttttaagaac aagataaggg atttatacta ggactgtctt aaaatgtctt aaacgaacgc
     1861 tcagagcttc tcaaagggtt ccttatgaac ggcttttagc aaaggagccg gaggcgactg
     1921 cgcagtataa tgtgagagca gagcgatcac acctttttag cgaaccgtag ggagcaaggt
     1981 ttggaattgg cagttttgat aaattcgcga acctgtttag agaaaaaagg agtgattttt
     2041 taggcgggaa aattagcctc ccctcttttt atatctcttt ttatatctct ttttatatct
     2101 cttttatgtc ggctgtgtcc ttactctccc aagcaattca gagttttttc aagtaggttt
     2161 tctacgcttt tcaagtaggt tttctacgct tttcaagtag gttttctacg cttttcaagt
     2221 aggttttccg acattattga gtatttttat aaagtatgtt acttttattt catactttat
     2281 aaaagtagga gaagcttatg gcaaatgaaa ttgtaaaata tgaaaataga ttaaatcata
     2341 ttcctctgag aaaatttaat agtcgtgaaa tgaacttatt tttttcaatt gcttcacgtg
     2401 tacgtgaaaa aggtgtagat gagattattt tttcatttca cgatttgaaa aaactaagcg
     2461 gttatacaga acgtggggaa caatttataa aagatcttag tagcacgtat gacaaattat
     2521 taagtattaa tgcttggaat gatgatggaa atactttaac taaatttgtt gctttcacaa
     2581 aatatagcat tatacgagat aaacaacttg ttataatttc agttaatcca gaatttaaag
     2641 gactttttaa tcaattaaag aactggacaa gatttaatct agagcaattt actaatttgg
     2701 atagcacata ttcaaaaact atgtttcgat tattaaaaca atatcgaact caaggctgga
     2761 ctgaattttc caaagaaaaa ttttttgatt tactagatat tcctaaaagt tattggaata
     2821 gtccgtcaaa tattgacaaa tttatcttaa ggccaattaa agaagaactc actcccttat
     2881 ttaaaggatt aactattcgt aaaaaatatg gtaaaggtcg aggtaaacct gttatcggtt
     2941 atcgttttac ttggaaagct gaaattaacc atgctgacga tttttccaaa gggaaacaag
     3001 aagatttacg tataaaatta tttaatattg atcacaatgg agaattaaca cgagaagaaa
     3061 aatggcgcgc taaagatcga atactaaatc ttcccttagg cactcatgaa gctgatttta
     3121 aacaacaaca acaaactgaa gaaaaacagg cagaaaaacg agaactttca aacaaactca
     3181 aacaagattt actaggaaat ttacaaaact tattcgatta agcttaagga gtatttatgg
     3241 cagataaaac aatcaaagaa cttgcggaag aattaggagt tagtaaaaca gcaattaaca
     3301 aaaaagtttc tgacaaaaat cgaaaacttt ggtttgcaaa aaacggaaac aagtttgtga
     3361 ttaacgaaac cggtcaaaaa gctataaaat caatgttttt agtcgataac gcaaacttaa
     3421 atcgaaaact agttggcgaa aaatcaaaaa ccaaaaacca taaaaacacc aaccaagttt
     3481 ccgaattaaa actcctttct ttcctagaaa aacagttaaa tcgaaaagat atacagctac
     3541 aagaaaaaga taatcaaata aaacaaatgc aaaaattact cgaccagcaa caacaactca
     3601 ctctacaagc gaaccaacaa attgagaacc tacaagaaca gctccattta acttatacag
     3661 aagaaactcc aacaaccgaa tcaactgcct tttctgaaaa aaaagcagac aatacacaac
     3721 cacttattga aaaaaagtgg tggcaaattt ggaaatctaa tagaaccaat ctctaaaatt
     3781 ttctagaagt tagttcggat agtagaggaa aaagttgtac tacctgatgg ggagatcact
     3841 caaattttta tgagaaagaa aaaatagttt acaactgtaa acaatcaatg tttatagttg
     3901 taaactatca aactatatgg tgacttattg cttaaaatag gttgaaatct cactcaattt
     3961 ttggtggaaa aacaaaataa attctaatcg attttgttga aaaagtcata aaaaaacaaa
     4021 tgtgatttta acaaaatttc aaaaaaatcg tttgaaattt cgtttatttt ttttgagaat
     4081 tttgatcatc gtagggtcat tgtagaatca ttatgagatc atcgtgggat catcgaataa
     4141 agtatgggaa aggcttgcgg tgcttggtat taagggcatt ctccgcctcc caggttcttg
     4201 accattttct ctcaacgtgg taaaaatccc acttataaga gaaaatggtc aagaacctaa
     4261 acggtcggcg aagaaaacat accaagcacc acaagcaaaa aaagttagag taacttccaa
     4321 aaaagaaaaa ttttttagaa caacttttga aaatttaatt ttgatttata tccgttcaat
     4381 ttaaacattt gataaactga aggctagtat ttaaaatgtg tatacaagtg gtagcgttaa
     4441 aaaaagtgga ggtataacct atgtt
//
LOCUS       DAZULR010000110         4416 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.117, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000110 DAZULR010000000
VERSION     DAZULR010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4416
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.117"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            59..913
                     /locus_tag="ACG8ZV_002749"
     CDS             59..913
                     /locus_tag="ACG8ZV_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFS4998001.1"
                     /translation="MENSIYLVTEPNTQLKDCYFNFCGYSKTEPRHSFGPAIREQYLI
                     HIVLEGEGYYSINDQKYFLKKGQGFVIPPGVSTFYQADEKNPWSYVWLGLSGNLVEYY
                     LKEIGVGKNHLTFKVENLNSFKGLIFETLSYDQDNLVSELSRQKQVYKFLELLLNSAS
                     YLNEGIITKKMNPFVRQTIEIIRENAYQKLSVKDIAVSLSIHENYLSRLFKNDMGISI
                     KEYISEIKISIANDLLSSTEYSIQQISDKIGFSTVQSFSKAFKKANGVSPGVYRKRRL
                     GLGIINGE"
     gene            1010..3259
                     /locus_tag="ACG8ZV_002750"
     CDS             1010..3259
                     /locus_tag="ACG8ZV_002750"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HFS4998002.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKISEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            3262..>4416
                     /locus_tag="ACG8ZV_002751"
     CDS             3262..>4416
                     /locus_tag="ACG8ZV_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4998003.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTR"
BASE COUNT         1556 a          625 c          806 g         1429 t
ORIGIN      
        1 gtaataatat aaacataata aaacaaaaat tatccaaatc taacatagga gggtggatat
       61 ggaaaattct atatatttag taacagaacc taacactcag ctgaaagatt gttactttaa
      121 tttttgtggg tattcaaaaa cagaacctag acatagtttt ggaccagcta ttcgagaaca
      181 atacttaata cacatagtgc tagaaggtga aggctattat tcaattaatg atcaaaaata
      241 ttttctgaag aaaggccaag gatttgttat cccaccagga gtatctactt tttatcaagc
      301 agatgaaaaa aatccgtggt catatgtatg gttgggttta agtggcaatc ttgtagaata
      361 ctatctaaaa gaaattggtg ttggaaagaa tcatcttacc tttaaagtcg aaaatttaaa
      421 ttcatttaaa ggattaattt ttgaaacttt atcgtatgat caggacaatc tagtcagtga
      481 attgtccaga caaaaacaag tttataaatt tttagaactc ctcttaaatt cagctagtta
      541 tctgaacgaa gggataatta ctaaaaagat gaatcctttt gttcgtcaaa caattgaaat
      601 aatacgtgag aatgcgtatc aaaaattatc tgttaaagat attgctgtca gtctatcgat
      661 acacgaaaat tatttatcac gattgtttaa gaatgatatg ggaatatcaa taaaagagta
      721 tattagtgaa atcaaaattt ctattgcaaa cgatctgtta tcatcaactg aatattcaat
      781 ccagcaaatc agtgacaaga taggattctc aacagtacaa tctttttcta aagcctttaa
      841 gaaagcaaat ggtgtttcac cgggagtata tcgaaaacgt agattaggtc taggaatcat
      901 taatggtgaa taaactaaac atttgatttt gataaatatt cgttacttta aacgcttact
      961 atttatgtga gcgtttttta taatgcaata aagaaacgga ggagagctta tgtataagga
     1021 taatgaaatg aatattattt atcgatcaga aaaccaacaa tttcatttgt ttaatcagga
     1081 gataagttac atttttaaga tatcggaaga tggtaaatta ttgcatttat attatggtga
     1141 gaacttacca gataatgact atagtcatct aattgagatg catcatcggc ctatgacaac
     1201 ctatagaaat gaaaacgatt tgctatattc gttagagcac ttaaaacaag aatttcctga
     1261 atatggtaca acagatttta gacatcctgc tatttcatta ctacagaaaa atggctctcg
     1321 cttatcagat tttgtctatc aagggtacga agtggaagaa ggaaaaccta aactagaagg
     1381 tttacctgct acctatgttg ataataatga tgaaagcaaa acattgaaag tttatatttt
     1441 agattcagtt acaaatgttc aagtagaatt attatataca atttatagag attatcctgt
     1501 tattactcgt agcgcgcgag ttatgaataa aggaaaagat attcaaataa tcgagaatat
     1561 tagcagttta tcattggatt tacccgatgc aaattatgaa tggcaacaat tatctggtgc
     1621 ttggggtaga gaaagaacta ttaagtcgcg tactttacaa caaggaattc aatcaatcga
     1681 atctactcga ggtatttcaa gccatcagca taacccattt gttactttaa aaagaaaaaa
     1741 tactgatgaa aatcaaggag aagctattgg tgcagcacta gtttactcag gaaacttctt
     1801 aattcaagca gaagtagata catgggatgt tactagacta caagttggca tcaatccatt
     1861 tggatttaat tggaaactca atccaggaga aatatttaca gcaccagaag cgattctggt
     1921 ttattcaagt aagggtttaa atgccatgag tcaaactttt catcaactat ttagaaaacg
     1981 cttagctcgt ggtaagtggc gagaaaaaga ccgtcctgtc ttaattaata attgggaagc
     2041 aacatatttt gattttgacg aagaaaagtt ggtaaatatt gctaaaaaag catttgatgt
     2101 tggtattgaa ttatttgtat tagatgatgg ctggtttgga gaaagagaaa acgattgtgc
     2161 aggattagga gattggcatg taaatcctaa aagactacct agaggaatcg gcagcctttc
     2221 agaaaaaatt cgtagttttg gtatgaaatt tggtttatgg tttgaacctg aaatggtgaa
     2281 taaggatagt gagttatatc gcacacatcc gaattggatt atttctacac ctaatcgaaa
     2341 acctaatcat ggtaggaacc aatatgtatt aaattttggg ttagatgagg ttgttgaaaa
     2401 tattttcgat caaatgtgta aaatcattga tgaatcaaac ttagattaca ttaagtggga
     2461 tatgaatcgt ccattgactg atgtatttga cagtcacttg tcagcagatc aacaaggaga
     2521 agtattccac agatatgtac taggcgtata tcgcttatat gaaaaactta taacaaaata
     2581 tcctaacata ctatttgagt cttgttcatc aggtggtggg cgctttgatc ctggaatgct
     2641 tcactatgca cctcaagctt gggctagtga tgattcagat gcaattgaaa ggttaaaaat
     2701 tcaatatgga actagtatgc tgtatcctct ttcgtctatt ggtgctcatg tatcaattgt
     2761 tccaaatcat caaacaaacc gtataacacc tataaaaact agaggaaatg tagctttttt
     2821 tggtgcattt ggatatgagc ttgacttaaa tgaattaagt gaaggcgatt tgaggattgt
     2881 aaaagaacaa attgcctttt ataaaaaata tagaaccata attcataatg gtacttttta
     2941 tagactatta tcaccattcg atgatgataa tcaaaccgcg tggatggttg ttagtcatga
     3001 taagaaaacg gctattgttg ctcattataa aacattaaat gaggtaaatg ctccttaccg
     3061 ccgactgaaa ttaaaagggt tagataatga cggactttat aatgtaggac aaaatagttt
     3121 gcgatctgga atggaattga tgagagcagg actagtctgt tcagatgcat ctagtggaca
     3181 aataaatgat cagaatcgac gcccagaaac atttgatttt gattccaaga tttgggttat
     3241 aacacaggag gaaaagtaga gatgaataac caaaaaagct tacttcaaaa aggagcaatc
     3301 ttaagtattt cactaatgtt aacaagctct caagcaatta atggtgttat tccacaaatg
     3361 aaacagtctt tggggatatc acaaagtcaa agtgaacttt taggaactgc accaagtata
     3421 actgttattt tgtttatctt attatctagt tactttgcca aaagaatagg aatgaaaaag
     3481 acaataattt taggtttatt attagctggt ataggaggaa ttattccagt atttacagct
     3541 accttccaaa ccgttcttat tagtcgagta atattaggtg ccggtttagg agtatataat
     3601 tcattggctg tgacatatat cagctcttta tactctggca atactagagc aacgctatta
     3661 ggtattagaa attcaatgga agctttaggt cagacaatcc ttatttttct tgctggagtt
     3721 ttagtgaaca ttaattggac ggcttcgttt ttagtctatg caattgcgtt tcctgtagct
     3781 ctcttattcg cgctaaaagt tcctgaaatt agagatgaaa atagtgacat acctgaaaat
     3841 catgtaaaag aaaagatgaa tccaatggtt tttgccctag ttctatttgc aatcttactc
     3901 gtaatgaata gtattgctat ttctgtacga tttgcatcaa ttgcaactga aattaaaggg
     3961 gtaaacttta atgctagtaa ctatttagct ctaatgccta tcttaggaat actagcagga
     4021 tttatgtttg gaccaataaa taagtggata ggaaaaggaa ccctatactt gggaattata
     4081 ttctttataa tttcaaattt gttaattgct gtgtcaaacg gtaatatgac gttcctgcta
     4141 acgggtttat ttttatcaag tataacagga tcatggtgct tcccatttat ctttagtaac
     4201 ttagataaag tcactacaaa gaatacaatt aattttgcta cttcattgat ttttattggc
     4261 tgtaatattg gtaattttat agctcctatt gctatgcaat tagcacaatt tctaacaaga
     4321 agtacaaatt tgactgctcc attttttgta ttcgcaggaa tatttattgt gatcctattt
     4381 gtaacatttt ttgcgacaaa taaaaaaaat actaga
//
LOCUS       DAZULR010000111         4377 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.118, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000111 DAZULR010000000
VERSION     DAZULR010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4377
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.118"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            73..234
                     /locus_tag="ACG8ZV_002752"
     CDS             73..234
                     /locus_tag="ACG8ZV_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HFS4998004.1"
                     /translation="MQDKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPV
                     DAISYGVRK"
     gene            253..1530
                     /locus_tag="ACG8ZV_002753"
     CDS             253..1530
                     /locus_tag="ACG8ZV_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4998005.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            1540..2196
                     /locus_tag="ACG8ZV_002754"
     CDS             1540..2196
                     /locus_tag="ACG8ZV_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4998006.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            2196..3572
                     /locus_tag="ACG8ZV_002755"
     CDS             2196..3572
                     /locus_tag="ACG8ZV_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4998007.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGVVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            3702..4115
                     /locus_tag="ACG8ZV_002756"
     CDS             3702..4115
                     /locus_tag="ACG8ZV_002756"
                     /inference="COORDINATES: protein motif:HMM:NF013068.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFS4998008.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDIADCRQKLFQTRNSSLEQLFIYFVSNF"
     gene            complement(4140..4377)
                     /locus_tag="ACG8ZV_002757"
                     /pseudo
     CDS             complement(4140..4377)
                     /locus_tag="ACG8ZV_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611630.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1699 a          522 c          761 g         1395 t
ORIGIN      
        1 catgaaaaat cctccagtgt gttttttatt attctacaca ccttattttt tctgtctagt
       61 ctagtgtagc cgattcagga taaggataag tgtattaatt gtggaaaatg taaaaaagtt
      121 tgccaaatga ataaagattc agttgagaat tgcaatcatc tggagtgtat cagatgtgga
      181 cgatgtaaaa atgcttgtcc agtggatgca attagttatg gagtaagaaa atagagagga
      241 gtagttagga aagtgataaa aaatgctata gcatatatta caagaaagaa aaatagaact
      301 ttaataattt ttatcatatt aactatagtt ctttcttgct tgtattcttg tttaacaata
      361 atgaaatcaa gcaatgaaat agaaaaggct ttatatgaaa gttctaattc ttcaatatca
      421 ataacaaaaa aagatggtaa atattttaat gttaatcaat ttaaagatat tgaaaaatta
      481 aaagaaattg aagaaaaaat aattcaatat gatggattag caaaactaaa agatgctaaa
      541 gtagttagcg gagaacaaag aataaataga gaagatttat ctgacgaatt taagaatgtt
      601 gtttcactcg aagctacaaa taatactaaa agaaatattt tatttagtag tggagtattt
      661 acaattaaag aaggtaaaaa tatagaagaa aatgataaga attcaattat tgttcatgaa
      721 gaatttgcta aacaaaacaa tctaaaatta ggtgatgaag ttgatcttga attactagat
      781 attgaaaaaa gtggaaaaat aaaaagtcat aaatttaaaa ttatagggat cttttctggt
      841 aaaaaacagg aaacatatac aggattatct tctgatttta gtgaaaatat ggtgtttgta
      901 gattattcaa caagccaaga gatattaaat aattcagaaa ataatgaaat tgcaaataaa
      961 attttaatgt attctggtag tgcagaatct acagacttag ccttaaacaa attgaaagag
     1021 cttaaaattg atgagtcaaa gtattttgtt gaaaaagatt ctaatgcgtt tgaagagtct
     1081 ttagagtcag tgagtggaat aaaatatata ataaaagtaa tgacttattc tattatgtta
     1141 ggtgggatgg ttgttctttc attaatcttg attctatggt taagggaaag aatttatgaa
     1201 ataggtatat tcttatctat tggaacatct aagatacaaa ttataatgca atttatattc
     1261 gagttaatat tcatatcgat accaagtata atatcttcct tatttttagg aaatgtatta
     1321 ctaaaagtaa ttgtagatgg attcattaac tcagaggatt caatgatttc cggtggaagt
     1381 ttaataaata atagtagttt tatgtcaaat ataacaacac ttggacaaag ttatttaata
     1441 ttaataagta ttattgtttt atcagttgta tttgcttctt cattaatgtt aatcaagaag
     1501 cctaaagaaa tcttatcaaa aataagttag gagaaaataa tggatatatt agaaataaag
     1561 aatgtagcat atagttatgc aaattctaaa gaaaaagttt tgtcaggagt aaatcaaaaa
     1621 tttgaacttg ggaagtttta tgcgatagta ggaaagtcag gaacaggaaa atctacactt
     1681 ctttccttac ttgctggact tgataaacct caaacaggaa aaatattgtt taagaatgaa
     1741 gatatacaaa ataaaggata tagtaatcat agaaaaaata atatatcttt agtatttcaa
     1801 aactataatt taatagatta tttatcacca attgaaaata ttagattagt aaataaatca
     1861 gcagatgaaa gtatcttgtt tgaactaggt ttagataaaa aacaaataaa aagaaatgtt
     1921 atgaaattat ctggtggaca gcaacaaaga gtagctattg ctagagcatt ggtatcagat
     1981 gctccaataa tactagctga tgagcctact ggtaatctag acagtgttac tgctggagaa
     2041 ataattaata tattaaagac attagctaaa gatagaaata aatgtgtaat agttgtaaca
     2101 catagtaagg aagtagcaga ttctgcggat atcattttag aactaagtgg taaaaagttg
     2161 aaaaaagtaa ataaaatgaa tttggaggtt gaataatgat aaaaaatgca tttgcttatg
     2221 taactagaaa aagtttaaaa tcattaatta tcatattagt tattttatct atgtcaactt
     2281 taagtctcat tagtttatct attaaagatg ctacggacag agcttcaaaa gaaacatttg
     2341 ctaatataac aaatagtttt tctatggaga taaatagaca agtaaatcca ggaacaccta
     2401 gaggtggggg aaatgtaaaa ggtgaagata ttaaaaagat atctcaaaca gatagtatag
     2461 actcctatgt aaaaagaata aacagtgttg cagatttagt tgattatgat attattgaaa
     2521 ctcaagagac tcttgcgaat caatcacctg aaagagcaaa gaattttaaa agaacagtta
     2581 tgttaactgg ggttaacgac tcaacaaaag aaacaaaatt tgtatcagaa gcatataaat
     2641 tagtagaagg aaagcattta gaaaatgaag ataaaaataa aatcttaatg cataaagatt
     2701 tagctgaaaa aaataacctt aaagttggag ataagataaa aataaaatct aatttatttg
     2761 atgctgataa tgagaaaggt gcagatgaaa cagtagaagt agaaattaaa ggtctattcg
     2821 atgggcataa tagcggtgta gtaagtgcag cacaagaact atacgaaaat acattaatca
     2881 ctgatattca tacagctgct aaagtttatg gtaataccga agatacagct gtataccaag
     2941 atgcaacatt ctttgtaaaa ggtgataaga atcttgatag tgtaataaaa gatcttggga
     3001 aattagatat aaattggaga gaatataatt tgattaaaag ttcatcaaat taccctgcat
     3061 tacaacaatc tatatcaggt atttactcaa tttcaaataa attatttttt ggctcattaa
     3121 tatttgcagg agttgtagtt tcattattat tattcttatg gatgaatgct agaaagaaag
     3181 aaatagcagt attactatca ttaggtatat caaaattaga aatttttggt caattcctaa
     3241 ttgagatggt atttatatca atccccgcat tcgttggttc ctatttctta gctcaatata
     3301 cagctgacaa gcttgggaat aatatattga ataaggttac tggtgatata gctaaacaaa
     3361 tagctaaaca atctgcatct agccaattag gtggtggggc agaagctgaa ggatttaaca
     3421 agacattatc aagtttagat atcaatgtat tacctaaatt catgatttat gtagttatat
     3481 ttatgagttt agtacttctt gtatcattga ttatttcttc attcaatata ttaagaagga
     3541 atccaaaaga attattaatt gacaataatt aaaattttcg gtgcttttta gcaccaaaaa
     3601 tgagagtgta atataaaccg tgtaagtaac catcaatcct aggcgggtgg ttgcttcacg
     3661 gtttttattt ttctaaaata agatcaagag gtgattacac gatggctaga aagaaaagaa
     3721 atcctgatgc tgagaagtta gctgaatcca ttttgaatac ttatcaaccc gaatctgtag
     3781 aggatatgca agatgtttta aaagatgtgt ttggtccctt atttgaaaaa atgcttcaag
     3841 gagaattgaa taaccattta gggtatgacg cccattctaa agagccaaag aaacatgaca
     3901 atcgacgaaa cggttatggc aataagacgc ttaaaacgag ctttggtaaa gtaaacattg
     3961 atgttcccag agaccgggag gcttcttttg aacctgagtt gattcctaat agaaaacgag
     4021 atgtctccga catcgcagac tgtagacaaa agctgttcca aactcgtaac tcgagcttgg
     4081 aacagctttt tatctacttc gtttcgaatt tttgaacaaa aaaataaagg ctccttgcct
     4141 ttccatagcc aggtggctaa tttctttaaa ttcattgcag caaacactag catcgtatgc
     4201 gtcgcgactt tttccaagcc tcgatacttg gtccaacgca tcccatgctt ttcttttgca
     4261 tccgcaaata ttcgttcaat cgtttgtttc cgttttttgt aaattgattt attcagatct
     4321 gttaggcgaa gatgttccac ttcatccatc agatctcccc aaacatgtct cgtgatg
//
LOCUS       DAZULR010000112         4216 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.119, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000112 DAZULR010000000
VERSION     DAZULR010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4216
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.119"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(37..1257)
                     /locus_tag="ACG8ZV_002758"
     CDS             complement(37..1257)
                     /locus_tag="ACG8ZV_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFS4998009.1"
                     /translation="MKLIGIVGSAAELSYNRKLLTFIQKQYHELFNLEIIEIKDLPLF
                     NQDDDQTNSPAIQQLNRKILMADGVIIATPEHNHTVPAGLKSALEWLSFKIHPLENKP
                     VMVVGASYYDQGTSRAQLHLRQILDAPGVNALVMPGNEFLLGKAKEAFDQEDRLIDPR
                     TVDFLGSTLASFVKFIKVVSTLAGPKKLPPEDLHATGTIATTIPDVDMSDDHWLEKAS
                     EAVGAVSGNTYVKLNRGLLTVDQINYFLDSMPMELTFADNNNQFLYYNLRQEAKEMLA
                     ARVPGQVGNPLANCHPEKSYKNVEWVIQQLRSGATDAVRVHVPKQVPEKYIVHNYQAM
                     HDENGEYAGINEYILDFKPIIEWYLQQTGQQLVGNEDAVSSASVHGGKTDAVTSASTH
                     DETAVDAVSSASVK"
     gene            complement(1277..1888)
                     /locus_tag="ACG8ZV_002759"
     CDS             complement(1277..1888)
                     /locus_tag="ACG8ZV_002759"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HFS4998010.1"
                     /translation="MKMKFIGLVGTNSTRSTNRELLQFMKNYFVNEAEIEIVEIKELP
                     LFNKPENTELPNVVKEIAGKIEQADGVIISTPEYDHAVPASLINALNWLSYGIFPFVD
                     KPVMITGASYGTLGSSRAQAHLRQILDSPELKARIMPSSEFLLGHSLQAFDEQGRLID
                     EEQVAKLRELFKDFLLFVTITSQLQHAHQANKREAESFSWETI"
     gene            complement(1931..2863)
                     /locus_tag="ACG8ZV_002760"
     CDS             complement(1931..2863)
                     /locus_tag="ACG8ZV_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HFS4998011.1"
                     /translation="MNQVIEETKIWQMMGTTITLQVGHEEPSRLLAELGEWLHVYEHR
                     FSAHDATSELMAINQAAGRQAVIVHPELFELIKLGKAHSCARNSYLNIAIGPVVQKWH
                     IGFEDALVPTKAEITELLLLTDPHQIQLDEKMKTVFLTKPGMMIDLGALAKGYIADKL
                     ITHCRERNAAFALVNLGGNIVVFGESPRRSDGAWRIGLRNPKGSREESLAVVKLNNQS
                     LVTSGIYERYLQNGSSVYHHIIDPKTGFPVKNDVASLTILSDSSVDGEIWTTRLFGAS
                     SLEVLKALEEQPGIEGAVVTKENQFLYTKGFEKI"
     gene            complement(3284..4144)
                     /locus_tag="ACG8ZV_002761"
     CDS             complement(3284..4144)
                     /locus_tag="ACG8ZV_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFS4998012.1"
                     /translation="MNIEKFITARKAANLSQKEVSEGICTQATLSKFENNGQVPSLKI
                     LIKLCNRINLPLVELFSSMNVINTQLDEQLEKAEFSLITSEYEQLTQILAAIDPKVID
                     ESELIARYYYLKGFEMIFTNAPITDVLFHFDQLLMAETANTLFRLLAYTGIGMVYARE
                     KELEKAEVYFNRVFEKIYTYPIRTTEDIWRVLNIVFHCGVFFAQDGDLETSDALLNYA
                     IDICSDNHLTYYLARAAAQLAKNAQAKNKSKAEVLELIQDALAFAKINKNKKLIDELN
                     HMKKMILLIN"
BASE COUNT         1198 a          852 c          690 g         1476 t
ORIGIN      
        1 tttattcttt atttaaaact ttgcaacaga acctttttat tttacagaag cactcgaaac
       61 tgcatctact gcagtttcat cgtgtgtgct ggcgctggtt actgcatctg tttttccacc
      121 atgaacagat gcacttgaaa ccgcatcttc atttccaaca agttgttgac ccgtttgttg
      181 taaataccac tcaatgattg gtttgaaatc aagaatgtat tcattgattc cagcatactc
      241 tccattttca tcatgcattg cttggtaatt atgcacaata tatttttctg gcacttgttt
      301 tggtacatga acacgtaccg catctgttgc tccgcttcgc agttgttgaa ttacccactc
      361 tacattttta tacgattttt ctgggtgaca gttggctaat ggattcccta cctgaccggg
      421 cacacgagca gctaacatct ctttcgcttc ttggcgcaaa ttataatata aaaattggtt
      481 attattatct gcaaaagtta attccatcgg catcgaatct aaaaagtaat tgatttgatc
      541 cactgtcaat aacccacgat ttaatttgac gtaagtattt ccagaaacgg caccgactgc
      601 ttcagaagct ttttccaacc aatgatcatc tgacatatca acatcgggta ttgtcgtagc
      661 aattgttcct gtcgcatgca aatcttctgg tggaagcttt ttaggccctg ctaaggtaga
      721 cacgacttta atgaatttta caaaacttgc taatgtactg cctaaaaagt caacagttcg
      781 tggatcaatc aagcgatctt cttggtcaaa tgcttctttt gcttttccca ataaaaattc
      841 atttccgggc atcactaatg cattcacgcc tggtgcgtcc aaaatttggc gcaagtgtaa
      901 ttgcgcgcgt gaagttcctt gatcgtagta agaagcaccc acaaccatta caggtttatt
      961 ttcaagtgga tggattttaa atgatagcca ttcaagtgca cttttcaatc ctgctggaac
     1021 cgtatgattg tgttctggcg tagcaataat taccccatca gccattaaga ttttgcgatt
     1081 tagctgttga atagcaggac tatttgtttg atcatcatct tgattgaaca gaggtaaatc
     1141 tttgatttca atgatttcta aattaaatag ttcatgatat tgtttttgga taaatgttaa
     1201 taatttacgg ttatatgaaa gttcagctgc tgatccgacg atacctatta atttcatctt
     1261 tgtttgctcc cctcgattaa atcgtttccc atgaaaagct ttcggcttca cgtttatttg
     1321 cttggtgcgc atgttgcaat tgactagtga ttgtgacaaa gagtaagaaa tctttgaata
     1381 gttcacgtaa ttttgcgact tgttcttcat caatgagtcg tccttgctca tcaaaggctt
     1441 ggagtgaatg acccaataaa aattctgagc ttggcataat tcgtgccttt aactctggtg
     1501 aatccaatat ttggcgcaaa tgtgcttgtg cgcgtgaaga acctaacgtg ccataagacg
     1561 ctccggtaat catcactggt ttatccacaa acggaaaaat accatatgaa agccaattta
     1621 atgcgttaat caatgaagca ggaaccgcat ggtcatactc tggtgtgctg atgattacgc
     1681 catctgcttg ttcaattttt ccagcaattt ctttaacaac atttggtagt tctgtgtttt
     1741 caggtttgtt aaatagtggc agctccttga tttcgacaat ttcgatttct gcctcattta
     1801 caaaataatt tttcataaac tgtaataatt cacggtttgt tgaccgcgtt gaatttgttc
     1861 ctactaatcc aataaatttc atcttcattc tctttccttt ctaacatcga tttctgactg
     1921 ttcgcacgta ctaaattttt tcaaatcctt ttgtatacaa gaattgattc tcttttgtta
     1981 caactgctcc ctcgataccc ggctgttctt caagcgcttt caacacttct aaagaagatg
     2041 ctccaaataa acgtgtagtc cagatttctc catctacaga agaatcagac aaaatcgtca
     2101 ggcttgctac gtcattttta actggaaagc cagttttcgg atcaatgatg tgatgataca
     2161 ctgacgaacc attttgtaga taacgttcgt agattccaga ggtaactaaa gattggttgt
     2221 ttagtttaac caccgcaagc gactcttcac gtgaaccttt aggatttcgc aaaccaatac
     2281 gccaagcacc atccgaacgt cttggtgatt caccaaaaac aacgatattt cctcctaagt
     2341 taactaaagc aaacgctgca tttcgctctc ggcaatgtgt aattaattta tctgcaatgt
     2401 aaccttttgc taacgccccc aagtcaatca tcattcctgg tttggttaaa aaaacggttt
     2461 tcattttttc atctaattga atttggtgtg gatccgttag cagaagtaac tcagttatct
     2521 ctgcttttgt tggaaccaat gcatcttcaa atccaatgtg ccatttttgt acaaccggac
     2581 caatagcaat attcagataa ctatttcttg cacaactatg tgcttttcct aatttgatga
     2641 gctcaaaaag ttcaggatgt acaatcacag cttgtcgtcc agcagcttga ttgatggcca
     2701 ttaattcaga agttgcatca tgtgcgctga agcgatgttc ataaacgtgc aaccattcgc
     2761 ctaactctgc tagtaatcga ctaggctctt catgcccaac ttgtaatgta attgttgtcc
     2821 ccatcatttg ccagattttc gtttcttcga tcacctgatt cattttgtac cttctttact
     2881 tgaactacgg attacatgag taattagttt ttatttttgt tactgttttc acaaccagat
     2941 gatacgcctg ctagatttat ttgtcaaccg attttatata tttttttata taataaggta
     3001 attttaatat aaaattttat attgtaaaaa aacaaataag ggaaacaaac aacacatttt
     3061 tgtgtgttgc ttatttccct ctaactatcg ttttctattt gatggttaac ctacttaaaa
     3121 taaatactgc aacgacaaac ggagatcaag catgctttgt aacgtatttt acgataatta
     3181 cgactttatt ttattactct atcttgctgc catacccgtc tatccctaat catctttggt
     3241 gaattttttc aaagttagca taacaaaaat aagtattttt tccttagtta atcaatagta
     3301 tcattttttt catatgattt aattcatcaa ttaatttttt gtttttatta attttagcaa
     3361 aagctagtgc atcttgaatc aattcgagca cttctgcctt cgacttattt ttagcctgtg
     3421 cgttcttcgc taattgggca gcagctcgtg ctaagtaata agtcaaatgg ttatccgaac
     3481 aaatatcgat tgcgtaattt agtagtgcat cacttgtttc caaatcaccg tcttgcgcaa
     3541 aaaaaacacc acaatgaaag acgatattta acacccgcca gatatcttct gttgtacgaa
     3601 tcggatacgt ataaattttt tcaaacactc gattgaaata aacttctgct ttttccaact
     3661 ctttttctct agcatagacc attccaatac ctgtatatgc caataaacga aacaacgtgt
     3721 tggctgtttc tgccatcaac aactgatcaa aatggaacaa cacatccgta attggtgcat
     3781 tcgtaaaaat catttcaaat ccttttagat agtagtaacg tgcaatcagc tcagactcgt
     3841 caattacctt gggatcaatg gctgctaaaa tctgtgtcaa ttgttcatat tcactcgtaa
     3901 tcagtgaaaa ctctgctttt tctagctgtt catcaagttg tgtattgatc acgttcatcg
     3961 aagaaaaaag ttcaactaac ggaagattga ttcgattaca taatttgatt aaaattttta
     4021 acgaagggac ttgaccattg ttctcaaatt tacttaatgt tgcttgtgta caaattcctt
     4081 cagacacttc tttttgagat aagttggcag cctttcttgc cgtaataaat ttttcaatgt
     4141 tcattatttt ctctccaatc agacctcaca cgaaaatcat ttctgtctcg attttagcat
     4201 gttttctttg ggaatg
//
LOCUS       DAZULR010000113         4100 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.120, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000113 DAZULR010000000
VERSION     DAZULR010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4100
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.120"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            137..310
                     /locus_tag="ACG8ZV_002762"
     CDS             137..310
                     /locus_tag="ACG8ZV_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998013.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            950..1423
                     /locus_tag="ACG8ZV_002763"
     CDS             950..1423
                     /locus_tag="ACG8ZV_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HFS4998014.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1432..1659
                     /locus_tag="ACG8ZV_002764"
     CDS             1432..1659
                     /locus_tag="ACG8ZV_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4998015.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            2295..2666
                     /locus_tag="ACG8ZV_002765"
     CDS             2295..2666
                     /locus_tag="ACG8ZV_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998016.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
     gene            complement(2922..3164)
                     /locus_tag="ACG8ZV_002766"
     CDS             complement(2922..3164)
                     /locus_tag="ACG8ZV_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFS4998017.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(3196..4098)
                     /locus_tag="ACG8ZV_002767"
     CDS             complement(3196..4098)
                     /locus_tag="ACG8ZV_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFS4998018.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
BASE COUNT         1187 a          724 c          639 g         1550 t
ORIGIN      
        1 tttttcggag aattaaaaaa tacaataaat aactttagtt actttaatgc gttcttactt
       61 tatttttata ttatcatttt tcttattcac ttctttggtt tatactattc ttataaataa
      121 aaacgaggta tgtcctatga tgaaaagatt gtactattca ttgatcataa cgattggcta
      181 tttgattgta tcaaatctag gaaatatggt atttggtatc agtaaagaat tcagttggac
      241 tactacatta tgggaatctc tattcttttt catcttcgta tttttgttac aaaattatcg
      301 aaaaaaataa acatgtgcca tctatctgtt ggcacatgtt ttaggattta tggtactttt
      361 tattcggcaa tccattttat ttttctactt cttcttaata cctctaacac ttttgattta
      421 taaactaatc caatgcatct acttgcgctt attaagctat ttcagctaga tagtaccacc
      481 ccatgcgtca atgcttgatt ttccttttgt ataacattgt ataagcaata aaggacaaat
      541 aagtggtgat tacaccaaac cattgaataa gaaaaattct gatacgtaaa taaacatgaa
      601 cttgaaaaaa ttaatgaatc ggttagctac tacgtagttg tcttttttct catacagttc
      661 tgttaactta cacttctctt cgctagataa taaaaaatcc tccaactgta ttgtccaata
      721 taatcccagg catctaaact agcattatag aagagacaca catagaatct aaaataactg
      781 gttttaaatg tttcttacaa tcaaaaaaag ctgttaaatg cactccacac cttcatactc
      841 tatcattttt tataaacgat atatttttat tgtttttcga taaaaaatag ttgttttaca
      901 ataattattc tgctatattt tagctatcaa agataaaaga gggataaaaa tgaaatttaa
      961 aacattgcta ttaaaatttg tcgttttagg tataagtgcc gtatttattt tgttcggcgt
     1021 acttttttat actcagatcg ctacaagcga aaaaggattc aattttgatt ggcagaccac
     1081 attatttgtt tctgtcattt actttgccct tctcctaggg atcgttattg cttatttctt
     1141 attgaaacta ttgaaaaaaa tcgaagataa ccaagctttt tccactcaaa gcttaaacat
     1201 actaaaaaaa atcgaacgaa ccattttgtt tattggtttc gccttttttg gcttacttcc
     1261 taaatttatg aaagtagcgg atttagacga tgctccaggt ttgatgttgg taggaatcgc
     1321 tgtcgtattc attccttttg cagtatacac attaacaagc gtgctggaaa aactgcttga
     1381 acatgcgatt ttacttaaga cagatcatga tttgacagtg tgaggtgcga catggcaatt
     1441 atcgttaatt tagatgtagt attagctcaa aaaaaaatga gtgtgactga attgagtgag
     1501 aaagtgggca ttacgatggc aaacatctct attctaaaaa atggaaaagc aaaagccatc
     1561 cgtttttcca ctctcgaaaa aatctgccaa gttttggagt gtcaaccagg tgatttgttg
     1621 acctataaaa atgactcgaa tactatacca gaagaataaa ataaagtaga acaaacagta
     1681 aataaaaaat aatctgaatg atagatgtgt gagactttta gaagttattt acgtctatta
     1741 ttcagatttt ttatttcgat tgaataccgt tttatctata aataagatat gtactgactc
     1801 atacaaaggg ggccttttct tctccatgta ctatcacttt tcctgataca actggtttcc
     1861 tgttacgttg tagttggatc tgcttttagt ataatacttt attcattcca ccagactgat
     1921 agcagtttga gcagtctaaa taatcatgta gtattacagg ccattctgtt tcataccttg
     1981 aagtgcttaa aacttcagct aatggcccat tgtgttaact cttactccat tcttttttag
     2041 taagctccca tatatactgt aaagccttct atatattatg tcatgttgct ttttaacatt
     2101 tactatgtag ttttgataaa atgatttgaa taacagtgat ggacaattct tttttatttt
     2161 taacattatt ttgataataa tgattattta tttaaaaata cattagataa catttgttac
     2221 gacacgaaaa agcttcacaa acaaatatcg ttattttaaa atgagggcga actcacacaa
     2281 ttaggaggaa tagtatgcca tttattgttt acttttttct ttcattactc gtgatctata
     2341 ttccattacc aacatttttc ctgctcgtca atcgtctagc agagcaacat gatacgattg
     2401 ctgctcttac gaaactttgt ttacttctat ttgtttgtct agattacttt acgagctatt
     2461 attggctaaa acagacaaga gtaaaaaaga gatattattt cttccttgtc tttttcaatc
     2521 tctttgagtt tctgatccat tgctttttac ttcatcagta tcatacgatc catttgtgga
     2581 tcatctgggt tttcaaagtg gtcgtattat tttgtatgtt cacctttcct atctcaagaa
     2641 aatttaggga ggcattgttt tattaaagaa gcttctctgt atcaataaag acacatttaa
     2701 ggaaaaactt ttaaaaatct aattgggaat ttgcccgcat aaataagagg ctgtgacaaa
     2761 agtcttgtca cagcctctta ttccgtataa acagtgttca aaagcttgca tcttcgataa
     2821 tatgcccaac caaatgaaaa atatgagaag ctatttttgt ttggctgttc ttattacttg
     2881 atgaagaaca gctttttcac gacctctttt taaaagtctt tttacagttt tcgagcaaag
     2941 aatgatacga ttagtactaa aatgatggca ccaatcaatg atggcacgat tgccattcct
     3001 gcaatacttg gtccccaaga acctaataat gcttgaccaa gtgctgatcc aactaaacct
     3061 gctacgacat ttgcaataat ccccatcgaa gaacctttat tcgtgattgc tcctgcaatt
     3121 gctccgataa ttcctccgac gataagtgac caaataaatc ccatgtttcg ttcctcctaa
     3181 tgttttactt ccttattact gaacccgtgg ttctgtattt tcttttactt tttgtgcgcc
     3241 gcttccagct gctgatttta ctttatctgt ttgattcgaa gcaaattcac cggttttttt
     3301 cgctgcgtca gttactttgt cttgcaccgt ttcttgatct ttttcaaatt cttcttttgt
     3361 tttgatgtcc actacgttag cgttgacttc gatcacttct aaatgtgtca tattttttac
     3421 ttctttgccg attacttctt gcatttcttc aaagattttt tcgatatctt tgccatattc
     3481 cacaatgaca tccatatcaa ctgctacttg ttttttaccg acttctgttt cgatcccagc
     3541 cgttacatta tctgtattca caagttttcc tgccacatta gagaagaaac caccgtttgc
     3601 agataataaa ccgtctactt gttcaattgc gattccgatg attttttgca caactttatc
     3661 ttcataattc agctcaccgc gcattgaatc ttcctgttca gaatcatgct ttccttggtt
     3721 atttgtatga tcagaaccaa gttttccttg tccgtttgtg tggtcagaac taagtttttc
     3781 ttgtgctttc gcatggtcag aaggatgttt ttgctcttcc acaggtttag aaggatcgat
     3841 tgcatcatgt tgttctggaa ctttagattc tggagttcct ggatgatgag gtgcatgctt
     3901 ttctgcatca tgtttcttct cttctactcc ttgttgaacg ttagggacta ctggatctgg
     3961 atgtgcagat actggtgctg ttttgttctt ttcatcgttc acaccatttg attggtttgg
     4021 tgtcgttggg tctggatgtg cagacactgg tttttggttg ttcattttat tgttattatt
     4081 tttgttattg ttattcatgg
//
LOCUS       DAZULR010000114         4093 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.121, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000114 DAZULR010000000
VERSION     DAZULR010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4093
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.121"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..153)
                     /locus_tag="ACG8ZV_002768"
     CDS             complement(<1..153)
                     /locus_tag="ACG8ZV_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HFS4998019.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TTIYRWV"
     gene            complement(475..696)
                     /locus_tag="ACG8ZV_002769"
     CDS             complement(475..696)
                     /locus_tag="ACG8ZV_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998020.1"
                     /translation="MEEEKIFEKRWELASVEQRARYHNLMSSYRNIDWTYKEKKYLLW
                     LCQLDVNTFETFEVILDKIKNSNEKRADL"
     gene            complement(794..1039)
                     /locus_tag="ACG8ZV_002770"
     CDS             complement(794..1039)
                     /locus_tag="ACG8ZV_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998021.1"
                     /translation="MDFPEVVKEVQEIGATISDSRSSPMNYQDAHGIKIIDQERNVRK
                     YTTINECVINENLCRAPITKHIKNRSKAKDGRTFTTF"
     gene            1279..1893
                     /locus_tag="ACG8ZV_002771"
                     /pseudo
     CDS             1279..1893
                     /locus_tag="ACG8ZV_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337511.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(2263..3264)
                     /locus_tag="ACG8ZV_002772"
     CDS             complement(2263..3264)
                     /locus_tag="ACG8ZV_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="HFS4998022.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYINNSSGQSVINKQIVENSDILLAIFGHKLGSPVDNYRSGTIAEIDY
                     FYKNSKGEVGVFFLDEPVPQVLAEEYIEVKKYRDSLEDKGFYGTYSKDNIRRFLTKKV
                     NYLIEKAQNNLESKRFDLDSISYKTPSVINKKVTGTDKDFDDNLDIFDPIEFDNDERL
                     LLIYAFMDENSIFSTDNSTYRKVVQWESDNNLRSYLSDRVFDVLEKLSKSGILKEEYD
                     SSFDEYPSRYILISEDYKKFKRYFLKNEKKISVIMEKYKAPIQADPFSNLDESDLPF"
     gene            complement(3423..3689)
                     /locus_tag="ACG8ZV_002773"
     CDS             complement(3423..3689)
                     /locus_tag="ACG8ZV_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFS4998023.1"
                     /translation="MMIKKLIEEKQKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            complement(3679..4035)
                     /locus_tag="ACG8ZV_002774"
     CDS             complement(3679..4035)
                     /locus_tag="ACG8ZV_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFS4998024.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVVNGRYVITHGFTKKTEKTPISE
                     LKHAKELREEWFTNDD"
BASE COUNT         1294 a          745 c          542 g         1512 t
ORIGIN      
        1 tacccaacga taaatcgtag tatgacaaac atttattcca cgatcatata acaattcctg
       61 aacttcacga tagcttagat tgtaacgcag gtagtaacca acagcgacaa taatgacgtc
      121 ttttttgaat tgtttgcctt taaaatgatt cattactctg tcctctctgt cttttttctc
      181 aattttacac taaaatagat tttttggaaa actttgcaac agaaccgttt ttactatata
      241 cttcttccca gaacttgtcc gtctccttca aattatctct acctctcgag ttcattgggt
      301 ggtttgccca tttattaaac atggaatcac ctttctcata ctcatatatt tatgtcctat
      361 ttcaattata tttatatatg cttaaataaa tttgtatcct gaaatttatt gtaatatgaa
      421 gctgtatttt acatatagta accaaagagt taataaaata aaaagagcga accattatag
      481 atcagctctt ttttcattgc tgtttttaat cttatctaga atcacttcaa atgtttcaaa
      541 ggtatttaca tctaactgac ataaccaaag caagtacttc ttttctttgt aagtccaatc
      601 aatattacgg taagaggaca ttagattatg gtaccttgct ctttgttcaa ctgaagccaa
      661 ttcccagcgt ttttcaaata ttttttcttc ttccattatt gatccctcgc aagacgctac
      721 ctcaaactta aataatgggc agcgaaagtc taattcctta gatctaagta tagcaaacaa
      781 atatgaaaaa aacttagaag gtagtaaaag ttcttccgtc ttttgctttg cttctattct
      841 taatgtgttt cgttatcggt gccctacaaa gattttcatt aattacacac tcatttattg
      901 ttgtgtattt tctgacattt ctctcttgat caattatttt aattccatgg gcatcctgat
      961 agttcatagg agaggagcgg ctatcagaaa tagttgcacc tatctcttga acttctttta
     1021 caacttctgg aaaatccatc catcctgctt cagctgtcaa aagtaataat ctataatatt
     1081 tatctttcct tttcaatcta agaaatcgtc accccattct ttttcttcta ttataaacta
     1141 tttaactttt agaattcaaa aaccgtttgt ctatttagag tttaccctaa atagacaaaa
     1201 atataacatt gaaaaattta gagttctaac gtatgattag ggtgtattat aaacgttata
     1261 gaaaagtagg gaataaattt gaaaattgct tatattagag tttcatccat cgatcaaaat
     1321 gaacaacgtc aaattgaaga aatgaaaaag tttggcgctg aaaaaatttt tatcgaaaaa
     1381 caatctggag cgacgattag tcatcggccg attttccagg aagctttaga ttttgtcaga
     1441 gagcaagata tttttattgt agaagccatt gatcgacttg gacgcaatta tgacgagatt
     1501 atcgattcag tgaattatct aaagaagaag aatgtgcgac ttattatcac cagtttaccg
     1561 atcatggctg aagcaattgg aaatcctctc ctagataaat tcatccaaga cttaatcatt
     1621 taaatctcag ccatgattgc tgaacaagaa cgtactgaat cgaaacgacg ccaggcacaa
     1681 ggaattaaaa tcgctaaagc aaacggcgtc tataaaggtc gtcctaagtt atacagtgca
     1741 gacaccaaag atcctcaacg tcgccttgtc tataggagta tcgttcagga tcttgagaat
     1801 ggggttgcta tctcaaagat tgcaacagac tacaatgtga ctaggcaaac aatttaccga
     1861 ataaaaaaag aaatcgacca actaattgta tgatttcttt tttgaatcac gtaattatta
     1921 attagctttg tcatcaatac agacaatcat tttagattca tctagctaag ttgattacat
     1981 ttatgttaaa aagaatttag ttaacataaa tataattgat gcataaatcg tccttattta
     2041 aaggcattta acattgacaa cttagtataa tgtatcttat gtaaactaat aagatttgaa
     2101 ttttatttta tacacactcg ataatagatc aattttatgg tcccccgcat ttacgattgc
     2161 acaagagaaa cataaagtcg acctattagc atttcttttc aattcaaaca ttaaaaaagt
     2221 ttatacctct gctactaaaa aatgaaatta tctatttaaa atttaaaacg gtaaatctga
     2281 ttcatccaaa ttggaaaatg gatcagcctg tattggagct ttgtatttct ccataataac
     2341 agatatcttt ttttcatttt ttaaaaaata ccttttaaat ttcttatagt cctctgaaat
     2401 caaaatatag cgtgatggat actcatcaaa agaagaatcg tattcttcct ttaaaattcc
     2461 cgatttactt aatttttcta gtacatcaaa tactctatca ctcaagtaac tccttaaatt
     2521 gttatcactt tcccattgaa ctacttttct ataagttgaa ttatcagttg aaaagataga
     2581 attttcatcc ataaacgcat atattagcag caatctttca tcattgtcaa attctattgg
     2641 atcaaaaata tctaagttgt catcaaaatc tttatcagtt ccggtaactt ttttgttaat
     2701 tactgaaggt gtcttgtaag aaatagaatc taaatcaaag cgttttgatt ctaaattatt
     2761 ttgtgctttc tcaattaaat aattcacttt ttttgtgaga aaccttctga tattgtcttt
     2821 gctatatgtt ccataaaaac ccttatcttc taaagagtcc ctgtacttct taacttctat
     2881 atactcttca gccaaaactt gtggaactgg ttcatctaag aaaaaaaccc ctacctcgcc
     2941 tttgctattt ttataaaagt aatcaatttc tgctatagtt cccgatctat aattatcaac
     3001 tggagaaccc aacttatggc caaaaatcgc taataatata tcactatttt ctacaatttg
     3061 tttattaata acactttgcc cagagctatt atttatataa gtaggaatcg cattcgtttc
     3121 ccatcgaatt ggcatcaaaa ttacttttgt attatctgta ttttctatat tccatctata
     3181 tatggtttct tctacttcat tcctctttgc tgctatatca cctggtgatg ctataaatac
     3241 ttttattaga tttatggttt tcatttattg tacctttctc tttatgtctc tttaaagtaa
     3301 tttttgtata aaatttattg acttttacac tataggacaa cttttatcta tttagtacaa
     3361 aaaggcccac taaactaatt gattagttag gagcctatta caggtatatt ttcaactcgc
     3421 ttttaagcaa attctactac cagctttttg cctaatgccc tagcgatatc atcaagttta
     3481 tcgaaagata cgttatcccc tctctcaatt cgagcaatag tagattgagt tgtatgtgct
     3541 ttttgtgcaa gctccgcttg agttaggcct gcttcctccc gtgcatgata aagagcaacc
     3601 gcagtttcga gttttcttcc ttcacggtca tatgcttctg caaaatcttt gtctttttgc
     3661 ttttcttcaa tcaatttttt aatcatcatt tgtgaaccac tcctctctaa gttcttttgc
     3721 atgtttaagt tcacttattg gtgttttctc cgttttttta gtaaatccat gggtaatgac
     3781 ataccttcca ttgaccacat ggaaatagat agctctttgg atgtttgatc ctaccttact
     3841 tcttaattcg tacaaattag tgtctaattt tttcacccat ttcaaccgtt gagctactag
     3901 catcccattc ttttctgttt cttctattgt acgtaaaagc ttcgcactat ctttttttgg
     3961 taatgtttcc aaccattcta aaaattcatc atgaccatta ggtcttttaa atgtttcaaa
     4021 agatattttt tccataccca attatatcat atattgattt tatattatag tatataacat
     4081 aaaaattcga att
//
LOCUS       DAZULR010000115         3896 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.122, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000115 DAZULR010000000
VERSION     DAZULR010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3896)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3896)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3896
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.122"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            289..1104
                     /locus_tag="ACG8ZV_002775"
     CDS             289..1104
                     /locus_tag="ACG8ZV_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4998025.1"
                     /translation="MVKIAGLSKGGKTVSQLYKQNYRDWRQFRKNIKDSYFILPTELE
                     KYLPNNKAINLYLYYCFKAKNEGGDSWHSVNTIAESLGVTTKTINTWNKTLVDLGMIA
                     RIDDNHLSKSTILLPLSSYYKLALDSSLKDVTESTVHEIDGNLVAVYHLFEWRKNEAD
                     ENYNVPYNTLCCVFKRKTQKDTIYKFILVQDEKISNFELSTPSSKIYDDAYRFECQDL
                     EALLSANNLNNIEHENFVVNTRFNLVSEKDSDLLDLLIELTKNLDKKENITVL"
     gene            1230..1487
                     /locus_tag="ACG8ZV_002776"
     CDS             1230..1487
                     /locus_tag="ACG8ZV_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998026.1"
                     /translation="MANLYIENKGDLNAIITLIVVMVKSIGNITIGMLFIILAAVLIF
                     MIVIWFLNERSKDNQHRRDMEIKSIESIDYLSIITLKKPRS"
     gene            complement(1739..2311)
                     /locus_tag="ACG8ZV_002777"
     CDS             complement(1739..2311)
                     /locus_tag="ACG8ZV_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFS4998027.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(2327..2932)
                     /gene="fic"
                     /locus_tag="ACG8ZV_002778"
     CDS             complement(2327..2932)
                     /gene="fic"
                     /locus_tag="ACG8ZV_002778"
                     /EC_number="2.7.7.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_function: GO:0070733 - AMPylase activity [Evidence
                     IEA];
                     GO_process: GO:0018117 - protein adenylylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein adenylyltransferase Fic"
                     /protein_id="HFS4998028.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
     gene            complement(3333..>3896)
                     /locus_tag="ACG8ZV_002779"
     CDS             complement(3333..>3896)
                     /locus_tag="ACG8ZV_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFS4998029.1"
                     /translation="YFKSEKDTSSLTLTLEEGVEPDKVTSKVINQLKEKGSLKHLGEY
                     EVLDTAMLTKGIGQILSTITYFITAVAGISLFIAGVGVMNMMYISVSERTKEIGIRRA
                     LGATRKSIMLQFLLEGLILTLSGGLIGYLLGMALAYSVGSLIKVNVSLDLFTILLAVG
                     VSSVIGLVFSVMPASEAAKKDLIDILR"
BASE COUNT         1294 a          715 c          582 g         1305 t
ORIGIN      
        1 aaaaataaga aattcaaaaa agaaaaaact ttccttaaaa acaaaaaata ggagtattca
       61 gtttcttaat agttttgtaa tagttgtatg tagaagtttt cttaatagtt tttgtaataa
      121 tttattaatc gtagtttata taacttattt gtaagtgact agagaattaa ataaaaaata
      181 attactatct agtacgaaat taattacata ggataatata ttaaggtgct ggactacaag
      241 taaaaaatac tgtatgatca tgacagattc aagaaaggag caataagatt ggttaagata
      301 gcaggacttt ctaaaggtgg aaaaaccgtt tcacaacttt ataaacaaaa ctacagagac
      361 tggagacagt tcagaaaaaa cattaaggat tcttacttta ttctaccaac agaacttgaa
      421 aaatatttac cgaataacaa agctattaat ttatatctgt attactgttt taaggcaaag
      481 aatgaaggcg gggattcctg gcattcggtc aataccatag cagagtctct aggagtgaca
      541 actaaaacta taaacacctg gaataaaacc ttagttgatt taggtatgat tgcacgtata
      601 gacgataacc atctcagtaa atcgacaatt ttacttcctc tctctagtta ctataaatta
      661 gcccttgata gttctttaaa ggatgttacc gagagcactg tccatgaaat tgatggcaac
      721 ttggttgcag tttatcattt gtttgaatgg agaaaaaatg aggctgatga aaattataac
      781 gttccttata acacactctg ttgtgttttt aaaagaaaaa cacaaaaaga tactatctat
      841 aaatttatct tggtccaaga tgagaaaata agtaatttcg aattaagcac tccttctagt
      901 aagatttatg acgatgcata tagatttgaa tgtcaagatc tagaagccct cctttccgca
      961 aataatctaa acaatataga acatgaaaac tttgttgtaa acactagatt taatttagtt
     1021 tctgaaaagg actcagattt gttagatttg ctgatagagc ttactaaaaa tctagataag
     1081 aaagaaaaca ttactgtact ataactagca tcggtccatc attaagtttg gactattaga
     1141 acacttgcta ttacagaaaa aggtatgcta gccacgctta ctatttattg gtatcaaaca
     1201 agtatcttaa tttgaaagga agatgattta tggctaattt atatatagag aacaaaggag
     1261 acttgaatgc cattattact ttaatcgtag ttatggtaaa atcaataggt aatatcacaa
     1321 taggaatgct gtttattata ttagcagcag tgctgatttt tatgatagtt atttggttct
     1381 taaatgaaag atctaaagac aatcaacacc gtagggatat ggagataaaa tcaatagagt
     1441 caatagatta tttatcgata ataacactaa aaaagccacg ttcctaaacg tgacttacgc
     1501 tgaacgatat gtgttgtttg gtagacgaac aaatcgttca ttataaatat atgatggtat
     1561 cctaatatag taagcgtggc tagcatacct ttaattactt taccttttac agttaccata
     1621 cacatttttt gagcagaaat caagtaaata aaaaaatatt atatttcaca acatgctaat
     1681 agactcatat ctagaacgca ttaagtattt acctgtctgg ttcgctgaga cttctttttt
     1741 aactttcttc aattttcttc tttattctaa aaagcgtact gcgactgaaa ccggttatag
     1801 cttcaacttc cttatacgat ttacctgaag taagcagttc atatgcgtgc ctcttcttcg
     1861 gtgtgattgt tgctttcgga cgtccttctc tgaaattagg attattcttt cttgcaaaca
     1921 tttttccttc ttgggtacgt tccacaatca tatcacgttc catttctgct acactcaaca
     1981 acgtccgtgt caccattcgc cccatggacg tattttcaat cgttcctaga ttcaaaacct
     2041 tgatcgttac gttatcatcg agtaaaggtt caatgatctc taatgcttct ctcgtgttac
     2101 gagcaaatcg atcaagcttc gtaacaacta tttcatctcc aggcttcaga ccagccaaca
     2161 gctgattgaa ttttggccga tcccgttttg tacccgtaaa tttttctgaa aaaatattct
     2221 tcttctctac gccgttctca agcaactgtt gaatttgttc ttttgtactt tgagaagcgg
     2281 ttgagacacg tgcatatcca tatttcgtca tttggtccac ctacttttac aaatcatcta
     2341 tcgtatactc agaataccct tcatagaaat agctgacatc gattcctttc atatataact
     2401 cgcgatcgtc aattttatca gtcagagcat tggaaattag atagcgtatt tccaaatcgt
     2461 ttatgggact tcgctccatt gcagaaagat agtctgcttt atcgattaag ttccaatcta
     2521 caactttttg caattcttcc tttaaaatga gatccagcca aattctagta cttcggccat
     2581 ttccttctcg aaatgggtga gcgatattca tctccacata tttcttgata atctcttcaa
     2641 aagaagtttg tggcatctga tcaatatgct gtaacgaatg ttctaaatac ataactggtg
     2701 caaatcgaaa atttcctttt gcaatattga ccgatcggat ttttccggca aaatcgtaaa
     2761 tatccgaaaa tagaaattca tgaatttcag ataaaccttt aaatgtacca acttcgattt
     2821 catttatttt tccacaatcg tacaattctt tcgctttttg tttactgagt ttttcttcaa
     2881 ccttagccaa ctcaacttga ttggttaatc ccaatttatt ctctaaaatc atgcgaaatc
     2941 tccttaactt tatgacataa gtttatgaaa cactctcaac cccattatat cgcgattttg
     3001 tttatgtgtc aaaaactatt aagtttctga cccccgatag atttttcaag tgtctctatt
     3061 ttgcacagtc tagttgacct ttgatacacc tctatattta tagagaatct aaaacatcaa
     3121 catggcatac tcaaaattct aaatattagg gataaagaat tctcctatac aatcaaaaat
     3181 ttcctttatt tcgaactccg gtcacctaac tctattgatc tcttacaagc caaagaatat
     3241 ctctatacta caaagaaaca atagggtgcc tggttggtct ctttgtgttt tattttagaa
     3301 tctagaacgt aaatattctt gtcattctga ttttatctaa gaatatcaat taaatctttt
     3361 tttgcagcct ctgaagcggg cattacagaa aagaccagtc caataaccga agatacccca
     3421 accgctagta aaatagtaaa tagatcaagt gacacgttta cctttatcaa agaaccaaca
     3481 ctataagcaa gagccattcc taataaatag ccaattaacc ctcctgaaag agttaaaatc
     3541 aaaccttcta aaaggaactg cagcataatc gattttcgag tagctcctag ggctcttctt
     3601 ataccgatct cttttgttcg ttcagataca gatatataca tcatgttcat tacacctacc
     3661 cctgcgataa ataaagatat acctgctaca gctgttataa aataagtgat cgtactgagg
     3721 atttgaccaa ttcctttcgt taacatagcc gtatctaaca cttcatattc ccccaaatgt
     3781 ttcaaactac ctttttcttt caattggttt atcactttag aggtcacctt gtcaggttca
     3841 actccttcct ctaaagttaa cgttagagac gatgtatcct tttcagactt aaaata
//
LOCUS       DAZULR010000116         3680 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.123, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000116 DAZULR010000000
VERSION     DAZULR010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3680
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.123"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..276
                     /locus_tag="ACG8ZV_002780"
     CDS             <1..276
                     /locus_tag="ACG8ZV_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific recombinase"
                     /protein_id="HFS4998030.1"
                     /translation="ELIKLANKGQDYEHLADEIDELRDKRQLLLVEDASLSGENERIN
                     ELIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEEHFVISFKSGIEMEI"
     gene            419..640
                     /locus_tag="ACG8ZV_002781"
     CDS             419..640
                     /locus_tag="ACG8ZV_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4998031.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGNEIKIGN"
     gene            656..1498
                     /locus_tag="ACG8ZV_002782"
     CDS             656..1498
                     /locus_tag="ACG8ZV_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998032.1"
                     /translation="MKIITINDVEYAVFAANEGTSKPQPHIIETKSGTIPEGKQLSLL
                     KEYLKQNDISPIKGATTYWCIDKVLKLDSSKEKTISETIHKQKYLSLTEENIEKQHKF
                     VGASSNYGKEGLIIHDVLNAFPLHNDLNTIAMKIAVIDVTNSTHLSQYKSRLSLYDLA
                     KVILEIPNFDDRLAKGDPQLINIIARNIGAVNMFSFASKYCTYHNVEVCGRDDYSIFD
                     GIVKNTLPHYIQGLTTNKIDTWRRSFDYEAFNECVGKLLDENNIHIPFRRRKLDHFLW
                     YANR"
     gene            1561..3363
                     /locus_tag="ACG8ZV_002783"
     CDS             1561..3363
                     /locus_tag="ACG8ZV_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HFS4998033.1"
                     /translation="MGLFDFLKKKQGKVSKHVDYQLASSLFRTGKVFAEKLEVDISNV
                     DEFRKTFIAFDVETTGLNSSSDRIVEIGAVLFKEGVPIQSFGTLVNPKVRIAASASAI
                     NNITNEMLNSAPNEQEVYPQLVEFLGDALDGKITMCAHNASFDFGFLSNTFSRLGYDA
                     KIKYVDTLSLSRKHIKGIVNHKQETVAEYFGLINDTAHRAESDADICGKIFWGVLDII
                     EESLEEQKKQIEKMTPDIKELEACAFIQDIIEKKGCDTSWIRYRKNSNNYVDVTCLYT
                     FLKFKFAKKGNYIIIRKDATNGIDLPIEPCTVSEGGTTNVRVYFRSPFDLTPLSNYIF
                     SAYSDCYNSMNEYMSVSNYTKKEAEQSLSMLKSISKSAMKELLFDAKNRGYDETEVNL
                     NIEKVISREDVIINGLHNRVSLNKIRNIGNWEKGFDAGYPYWERGETARKNGKVDEAI
                     ALFDKARYNGYDAPALYDSYAKAYRKIKDYDNEILILDEGIMRKTRHDVGTLEARRDK
                     AIKLLFAKQEAERIAKEKSDFLKANKKEDAISEPSKKRGRQIIQMTDDGTIIKEFDTI
                     ASAVKEVGVNSKSIRDAANGVQKHAGGYYWKYKD"
     gene            complement(3422..>3680)
                     /locus_tag="ACG8ZV_002784"
     CDS             complement(3422..>3680)
                     /locus_tag="ACG8ZV_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HFS4998034.1"
                     /translation="GITISIPPRKNMDKSEKLDHSLLGKQRKTVGTVFSSLEKLGCQN
                     FNSRSVKGLESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT         1311 a          522 c          750 g         1097 t
ORIGIN      
        1 gaactcatca agctggctaa taagggtcaa gattatgaac atctagcaga tgagattgat
       61 gagctgagag acaagcgaca gctcctttta gtagaagatg cctccctcag tggcgagaac
      121 gagcgaatca atgagctgat tgaatttatc cgcaagaaca aattccgtac cttagagtac
      181 gatgataagc ttgtaaggaa gataatccag agcgttacag tctatgaaga acacttcgtc
      241 atatccttca aatctggcat cgaaatggaa atatgaaaac cagaagtaaa tagcccatga
      301 ttctacagta gagtcgtggg ttttcttttg cttgctgatt ataataatat tttaataact
      361 attgttatta taaaccaaat gatttataat attcttagcg taaacttgga ggtgctgtat
      421 gactacggca gaaatgatta aagaactgtg tgagcaaatg aatataagtg tttccgaact
      481 tgctagacgt attggacaga ctccacagaa tttcaataag aaattacaac gagaaacggt
      541 aaccttagat gagttgaaag cgattgctga tgtgctaggt gtcaagtttg tgcaggcttt
      601 tatattgcct gatggcaatg aaataaagat aggtaattag gaggtgtaat ttgtattgaa
      661 aatcataaca ataaatgatg ttgagtatgc tgtatttgct gctaatgaag gtacttccaa
      721 accacaacct catatcatag aaacgaaatc tggtactatt ccagaaggaa aacaactgag
      781 tttattaaaa gaatatctta agcagaatga tatttcccca ataaaaggag caacaacata
      841 ttggtgcatt gacaaggttc ttaagcttga ttcaagtaaa gaaaaaacta taagtgaaac
      901 aatccataaa caaaaatact tatctttaac tgaagaaaat attgagaaac agcataagtt
      961 tgtaggtgca agctctaatt atgggaaaga aggtctaata atacatgatg ttttgaatgc
     1021 atttcctctt cataatgatt taaatactat tgcgatgaag attgcggtaa ttgatgtaac
     1081 aaattcaaca catctttctc aatataagag caggttgtct ctatatgatt tggctaaagt
     1141 aattctggag attccaaatt ttgatgatcg gttggcaaaa ggagatcctc agttgataaa
     1201 tattatcgca aggaacattg gtgcagttaa tatgttctca tttgcatcca agtactgtac
     1261 atatcataat gtggaagtgt gtgggagaga tgattactcc atctttgatg gtatcgttaa
     1321 aaatactctt ccacactata tccaaggact aactacgaat aagattgata cgtggcgaag
     1381 aagttttgat tacgaggcat ttaacgaatg tgttggaaaa ctacttgatg aaaataatat
     1441 acatattcct tttagaagaa gaaagttaga tcacttcttg tggtatgcga ataggtagaa
     1501 tataagaaaa aggcatcgta aaagtgattc tggataaaat taatggggga ggaaataata
     1561 gtgggattat ttgattttct aaagaaaaaa caaggaaagg ttagtaaaca cgttgattat
     1621 caactggctt ctagtctatt tcgtactggt aaagtttttg ctgaaaaatt ggaagtggac
     1681 atatcaaatg tagatgagtt tcgtaaaact tttatcgctt ttgatgtgga aacaactggc
     1741 ctaaattctt cttcagatag aattgtagag attggtgcgg tgctatttaa agaaggagtt
     1801 ccaattcaat cattcggaac tcttgtcaat ccaaaagtta gaattgcagc ctcagcttcg
     1861 gcaataaata atataactaa tgaaatgcta aactctgctc caaatgagca ggaagtttac
     1921 ccccagttgg tagaattttt aggagatgca ctagatggaa aaatcactat gtgtgcacac
     1981 aatgcaagtt tcgattttgg atttttaagt aacacatttt ctagacttgg gtatgatgct
     2041 aaaattaagt atgttgatac tctgagtctc tctagaaaac atataaaagg cattgtaaat
     2101 cataagcaag agactgtagc ggaatatttc ggattaataa atgacactgc ccatagagcg
     2161 gaatcagatg cagatatatg cggaaagatt ttttggggtg ttttagatat tattgaggag
     2221 tcgttggaag aacaaaaaaa gcaaatagaa aagatgactc cagacataaa agaacttgaa
     2281 gcttgtgctt ttattcaaga tattattgag aaaaaaggat gcgacaccag ttggatcagg
     2341 tatcgaaaaa acagtaataa ttatgtcgat gtaacttgtc tatatacatt cttaaagttt
     2401 aagtttgcta agaagggaaa ttacatcatt attagaaaag atgctacaaa tggaattgat
     2461 ttacctatag aaccttgtac tgtaagtgaa ggcggtacaa caaatgtgcg agtctatttt
     2521 cgtagcccct ttgacttaac gcctctttca aattatattt tcagtgctta tagcgattgt
     2581 tataattcta tgaatgaata tatgagtgtt agtaattaca ctaaaaaaga agcagagcaa
     2641 agccttagta tgctgaaatc tatttcaaaa tcagcgatga aagagttatt attcgatgca
     2701 aaaaatcgtg gatatgatga gactgaagtt aacctaaata ttgaaaaagt gatatctaga
     2761 gaagatgtaa ttattaacgg gttgcataat cgagtttcat taaacaagat acgaaatata
     2821 gggaattggg agaaaggatt tgatgcaggt tatccatatt gggaacgtgg agaaactgct
     2881 aggaaaaatg gcaaagtaga tgaagctatt gcactttttg ataaagctcg atataacggc
     2941 tatgatgctc ctgcgctata tgattcttat gctaaagctt atcgaaaaat taaggattac
     3001 gataatgaaa ttctcattct tgatgaagga attatgcgta aaacacggca cgatgttggt
     3061 actttagagg ctcgtaggga taaggcaatt aagctattat ttgctaaaca agaggcagag
     3121 cggatagcta aggaaaaatc tgattttcta aaagcgaaca aaaaagagga tgcgattagt
     3181 gagcctagca agaagcgtgg aagacagatt attcaaatga ctgatgatgg aacaataata
     3241 aaagaattcg atactatagc ttctgctgta aaagaagttg gcgttaactc aaaaagtatt
     3301 agggatgctg caaatggagt tcaaaaacat gctggaggat actactggaa atacaaagat
     3361 tagcagataa tctaagataa cctaggatct tcttaataga tacccgtggt gctagttaat
     3421 tttaatatcc taaagaatat ctcaaagttc cttcaaaacg tcgttgtgct cgacttaata
     3481 gaacactgta agccagtaat atgctttcaa atctactctc tagcccttta acagaacgtg
     3541 agttgaaatt ttgacaacct aatttttcta aggaagaaaa aacagtccca actgtttttc
     3601 tttgttttcc aagtaagctg tggtctagtt tttctgattt atccatgttt ttacgtggcg
     3661 gaatggatat agtaatgccc
//
LOCUS       DAZULR010000117         3678 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.124, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000117 DAZULR010000000
VERSION     DAZULR010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3678)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3678)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3678
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.124"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(184..1503)
                     /locus_tag="ACG8ZV_002785"
     CDS             complement(184..1503)
                     /locus_tag="ACG8ZV_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HFS4998035.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
     gene            1760..2230
                     /locus_tag="ACG8ZV_002786"
     CDS             1760..2230
                     /locus_tag="ACG8ZV_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HFS4998036.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            2452..3555
                     /locus_tag="ACG8ZV_002787"
     CDS             2452..3555
                     /locus_tag="ACG8ZV_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HFS4998037.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLRDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
BASE COUNT         1182 a          629 c          789 g         1078 t
ORIGIN      
        1 aattctttgg cacattttat tgaaatatgt atcactaata tccctatcaa ctgattttga
       61 ctaaaaagtt acttcaaaca ttcactgttc aaaaatattg aggaataaat tttgggtgta
      121 aggcattttg agcatacttc tccctggata acttcccagt aaaaaaatcg ttagattgtt
      181 ggattagatc cattgactgg ctcgcctcag gcgagcaaag accctgtaga attcattctg
      241 atacacatga taactagata atttgagata gactcgtcta cccgtttgga ctaatttccc
      301 agcaactttc agaaacttca atcgaataga atgaatggtc attccctttt ggacttcttc
      361 aaagccaatc gttcttaaga agttgactaa gttgtaagct atcaagctga gcatcattcg
      421 gacatgattc tccaaaaagc gaggactgtc tgttttgtca aagtaaaagc cagctttcgc
      481 ttctttaatg aagttctcca ttgtgccacg tttggcatag atagaaaaga tggtatcagg
      541 agaaacattt tctgatagat tcgtcacgat aaattcatgt cgaaagagta gttcgcccgc
      601 ttcacgtgtt gagcgtatac acacgcgacg actttgtgac caggattgtg cttgataagt
      661 ggtcgagaag tactgaactt ctcgttcttc ccacttttga ttatcgccat aaagtactga
      721 tttctcagct atttgaccta gtctacgatt attcttcagt cgaataacat aatgactctt
      781 ttttgattca cacgaatcat acacaccagg tgtagcgaac ccgctgtctc cacgaaccaa
      841 gatgtcagtg tttggtagag agtgattata gtgctctaat aaaggtgtga gaaactcctt
      901 tacgcctttt gatgtatatt gatttcctga acgtagttca gcttttaaga agtcaccagt
      961 caatccgtca aaagctacca atggatggta accataggtt tggtagtgtg tattataatt
     1021 cgtttgttct tggtgaccaa atgtatctga atgggtcgaa tctaaatcaa tgattaattc
     1081 cgtatcatta cggatgaggc gtgctttatc gataagttct tggttcaaag cttgaagttc
     1141 atggatattc tcctcagata gtcgatctaa aaatcgggaa agtgaagatt gagaagcgag
     1201 ttctttccta tctaaaacag ctttaaacac aggatcttgt ctcaggagat tagctgcaga
     1261 atcagctgag taaccagcaa ttaattgcat aatgaactgc tcaagtatgg ataagttgtc
     1321 atgagtaaaa tacgctcgtt cgtcttcaat gtgaatgtgt tgcttagcca gttcagaaaa
     1381 accaaagatg ttcatcagct ctttcactag gacgagaccc gaatcactcg ataattgacc
     1441 acctgtatga gaaatagtga tatttgaatt gaattttact tggtttttgt gtaagctagt
     1501 catgaaaaga actcctttct tttggttggt ttagtcactt taaccatagc agaaaggggt
     1561 tcttttttca tcacttaacg ggtgaagatg aaaaagtaat tgtaagctgc cgtgaggcag
     1621 tttcacatgg ttttaattaa aagtatgaat tattcaggta gaatctctga agaataaatc
     1681 acgtgatcgt gacgataaaa tacacttacg tcaggtgata aaaaatacat aagtagaaaa
     1741 ctaagaggag gaacagaaaa tgaaagaagt tcaattgatc agaaaaagcg aactatcaga
     1801 aggtggttgc aatgcatgcg gcgtagtaga agcaacaagc tatacattaa agcttggtgc
     1861 caacaaagcg ataatctctg agttgacagt aggcggtctt gtggacagtc tggcgcttgc
     1921 tgaaggtttt attggagaag atatttatga gatgttttca gaaatccgtc agttaaaaaa
     1981 aggggaaaac tgcatagagg ttcatcatga gagcccgaat gtgagattca aacgtggtga
     2041 taatgagatg atcttcaata atcatgtgtc cgatcacacc gagctatatg gaatcgtgaa
     2101 tcaaatacta actgagcttt ttggattggg accttatgcg ttcaaggaag aaaacggtaa
     2161 tccaaaatta aacgaagaat ggcaagaaac gattgaaata caaagaaaca acccgcactt
     2221 atttcaatag gcatccacag tatttcgtaa aagggacttt gacacgactt ttgtcaaaat
     2281 cccatcgttt tttatctatt tgtgttctaa acatttcttt cagagtagta acaactggaa
     2341 tgactgaaat gtaaacagat tatttgcctg tatcaatacg gaagagtaat ataaagtgtg
     2401 taaacgctat catattattc attcaatttt ttatagaggg aaggcattga aatggaaaaa
     2461 acgtatcaag caggtacaaa tgaaggaata gtggatttta tcaatatgga agatttagaa
     2521 atagccgctt cacaagtgat tccagctggt ggttatggtt acatcagcag tggtgctggc
     2581 gacttattta cttatcaaga aaatgaacgg gcattcaatc atcagctgat tattcctcat
     2641 gtattaagag atgtagaatt acccgataca actacacatt ttgacaaaga aacgctgact
     2701 gcaccaatca tcatggcacc agttgctgct catggcttag ctcatgtgaa ggcggagaaa
     2761 gcttctgcaa aaggtgtagc agattttggg acgatctata cagcaagttc ttacgcttct
     2821 tgtacattag aagagataag agaagcaggc ggggagaaag caccgcaatg gtttcaattt
     2881 tatatgagca aagatgatgg gatcaatttg gatattcttg aagtggccaa gcgtaatgga
     2941 gcaaaagcaa tcgtattgac agcggatgca acagttggcg gaaaccgtga aacagaccgc
     3001 agaaatgggt ttaccttccc actgccaatg ccgatcgttc aggcttatca atcaggagta
     3061 ggccaaacga tggatgctgt gtacaaatct tccaaacaga agcttagtcc aaaagatgta
     3121 gaatttattg ctgctcattc tgatttgcca gtctatgtga aaggtgtcca gtcagaagaa
     3181 gatgtctatc gttcattaga atctggtgct ggcggaatct gggtatctaa tcatggtggc
     3241 cgtcaactag atggtggtcc agcagcgttt gattcgttgc aatatgtggc agaagcagta
     3301 gataaacgtg taccaatcgt gtttgacagc ggtgtacgac gcggacagca tgttttcaaa
     3361 gcaatcgcat caggtgcaga tcttgttgct attggcagac ccgttattta tggattgtct
     3421 ttaggaggaa gtacaggagt ccatcaagtg tttgatttct ttaaaacaga attggaaatg
     3481 gtcatgcaat tagctggaac acaaacagta gaagatatca aaaaaataaa attgcgtgag
     3541 aatcgtttta tttaagaaac aaatgacgaa aaaaatagga gtgcggcaga tgatgccgta
     3601 ctcctatttt tatagttcaa ggatgtcact aatagaataa tttgaaacga aaaaataaaa
     3661 ttgaaatatt ttttcata
//
LOCUS       DAZULR010000118         3467 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.125, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000118 DAZULR010000000
VERSION     DAZULR010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3467
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.125"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..2232)
                     /locus_tag="ACG8ZV_002788"
     CDS             complement(<1..2232)
                     /locus_tag="ACG8ZV_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFS4998038.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTSNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTG"
     gene            complement(2904..3172)
                     /locus_tag="ACG8ZV_002789"
                     /pseudo
     CDS             complement(2904..3172)
                     /locus_tag="ACG8ZV_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
BASE COUNT          974 a          766 c          549 g         1178 t
ORIGIN      
        1 accggtttgt agcgtttctc cttctcggtt ctgtaactca aaaacagctc cttgaaggac
       61 ttcaccactg ccttcagcat gtttaattag ttcaacacca cccgtatcaa ggatgttttc
      121 aatggttaac gtcacttctt ctatggagta ttcatttata aaaacatcat gtaccgtcgc
      181 atctaaaaga tacccttccg gtgcttctgt ttctcggact tgatagctac ctacaggaag
      241 cggttcactt aaaaattctc cgttttctgc cgttatacct tcttgtatca cttgtgaatc
      301 gcttgataaa atttcaaatt ttgctcctgc cagcctttgg ccattctcat cagttttaat
      361 tactttaata cgcccatcga ttttccttgt tcttacagta ctcgtattca atcgattgtc
      421 actattcaca agcgttgcaa agtttaaaat ttgatcgccg accgcatacg cctctacatt
      481 gaccttaaaa gagagggtaa aacttgtcgg accaccaatc gtattattcg cactgaaacg
      541 aactattcca ttattgactt cggcatcaat gaaagaggga atatctgata gaaatgacac
      601 aaattccatg ccttcttcca aaacatcttc aataacaagc gtattgcttg ttccagaaaa
      661 catcgagaca tgcagagtat acgttagttc attttcattg agattgataa catttttgtc
      721 cacacttttt cttaaagaga ttgccggaag attactttca gggattctca agcggtagtc
      781 tcggctcatt acctgattat tgtaggtcat actcgctcga ttccgagaaa acccatcctc
      841 ttgtcttcct tcattgaaca agtcgacatc ggtcacttca agagcatatt caataaaata
      901 cgattgaccc tctgctagat taccaaagtc cacaacaagt gtattcgttt ccttattaaa
      961 agatactttg tccacaaatt cctcggaaac ataatgagtt ctaacgtttg cttcacctgg
     1021 attcgttact tctgcgatcc gaaccccacc tgaaataggt tctctatttc cagtggaact
     1081 ccatgtagtc ggattcggtg ccaaagttgt tccttgcggt agtacatcgg taaccactac
     1141 accgtctttt cgtgatcctt cataatttac ctgcaaaata aatttattac tgttggtcac
     1201 gtcttgcccg tcaatcagca gattcccaag atttccttgg ctgtcgattt ctctagagcc
     1261 atagtataat ttcgaaaaaa tgggtcttga tgaaggaata ggcgtaattg aaaattccgt
     1321 gtttgctgct cgctcagcat aagtaagact cacttgaaag tcattatttg gctcagtacc
     1381 gcctgattga aagaaagcaa cttcaaacgt gatactgaat gtatacgact gagcggcttc
     1441 atttaatcct tcataatcaa aggtaaatgg aaaaacaacg tctgtgcctt cttggtaaaa
     1501 tgccagtggc tttaaaggtg aatcatcagc gacctccact ctaatgaact caattaagcc
     1561 aatcgatgct ctaggaactc gtacgaccat ctccccatat tcttcaagaa tatcgccagc
     1621 gcctccttga atgtatccct ttaacgtttg tgtatgcctg ctcggcaaag tggggcgctc
     1681 agcagagatg ccgatgtcat aattcaagag ctcctcttgt ctttcaatct gagattcctg
     1741 cgttatagat ggctcagatg atctggcttc attaaaagat tcacttaagc tttcttctgg
     1801 tatattaaaa gattcacttg tgctttcttc tggtacatta aaagactcac ttgtgctttc
     1861 ttctggtaca ctgatttcta ttgagaccgt atttgattga atatcaccgc ttcttgcggt
     1921 caattcgtat ttacctgaat gctgggaaga ataagtaatc agacgttcgt aatcattgag
     1981 ttgcttcact tccccttcaa tcaaatcctc actcttatca atgaccaatg catttagcag
     2041 gtctggtgtt cctctgactc gcaactggaa ctgctcaccc aaagcagcct cctcttgatc
     2101 aacttcgatc gtcagcgaac gctctggctg ttctgctaaa gactcagcta gaaccgttat
     2161 gttcccaaat tgattgatca caataagcat aactagaaac atacttaaca gtttatgaaa
     2221 tttgttcctc actattactc ccccttataa ttttgactaa acaacaaggt acccgataat
     2281 tttctaaaaa gattccccaa ctcaaaatgg ctgcgttacc tccctcgtat tttcggttca
     2341 actcaagcgt tgcaatgtaa gctgtaaaca aagctaatga ttgccgattg tcttctgttg
     2401 attgattcga tagctttgta tgacttttag ttgtccgtgt ggcttaacca taattatgat
     2461 ttcacgattc ctcctgccag tgccttgcac aagctggagc gtaaccctaa tagttatttt
     2521 gttaatgtac ttatatactt ttatactttt ccattagaaa caatcactaa atcgttgata
     2581 ccaaggtcag actctagaat ttcatcagtg agtccctgta ttggttaacc ttcatcaatc
     2641 ccaaaaaaat atatcaatgc ttagcatcaa aatgaatata tagtttagaa tacttgggat
     2701 tcatcgataa ctgatcgctt atttggccat attatttggc acttggttca actaaacgca
     2761 tttaggatgt tccttcattc tcgtcatgga tgttctcaaa ccgtcattac taataaactg
     2821 tccaccgaat cgatggttca tttcttgcat tttccacgtc caattactct ttttgctctt
     2881 tatttgggcg tagttttact ttcttaactt gtatcgtctt ccatcaactc cttaatcatc
     2941 ttcttagctt tattggctcg gtttccttgt aaaaggtatc tacaaatagt gacaatctgt
     3001 attaaatctt catcattttc tgtaatgtca ataatttcta tattctgtac catatattgc
     3061 aaagggtttc actaagttca taaccgaagc gaattaaaca acttttgtat agaataacta
     3121 ccttttctat ttttccattg gtaattctat ctattaattg gtttaatcct tttgttgtag
     3181 ttgattccac taccaagatg attctctcga attttaaagc ttgaagatgt attgctattt
     3241 ttgctaactg gcgtatttgc aactattttt cccttctatt cttccttcat tgattcccct
     3301 ctaaaattac tatccataaa aaattgcata aatgacaata gtatttatat tagtcatact
     3361 gctttttaac acagcaaatt ccagaaaaac attcgttaca tatttgtgaa tttttccaaa
     3421 aaataacatt tttataaaac aacgaaaaat aaatcactac cagtcaa
//
LOCUS       DAZULR010000119         3211 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.126, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000119 DAZULR010000000
VERSION     DAZULR010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3211
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.126"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..821
                     /locus_tag="ACG8ZV_002790"
     CDS             <1..821
                     /locus_tag="ACG8ZV_002790"
                     /inference="COORDINATES: protein motif:HMM:NF013235.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFS4998039.1"
                     /translation="TMVDSNGKPILNKYGKPKKVVKMPIDNSVTLSIQRLRHLASLGN
                     ESNKQIVDRYFSNQPEPLTINEQMELLQTGINLHSIYMVDENENEIITAPAIARWVIN
                     KHTLEVTARINPEYLEWFSEVVNQYILFNLRDFVKLKSKYSMILFLELSTFWNTGMYY
                     KRINDLREILGVNPTRNNRDFINNVLKPAIAALKEYFPELSLTVEKNSSDSRKITHVR
                     LKFDKLTITDMQERLRSSEGASLVEYQQELENMEGEEKAVNDPTPEIDLSNVEW"
     gene            935..1303
                     /locus_tag="ACG8ZV_002791"
     CDS             935..1303
                     /locus_tag="ACG8ZV_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998040.1"
                     /translation="MENTNQTPNTAPTNQTSPAERKADLIRLYSRLEGMKLQHVPTAP
                     KAPDGFPKSAESLEFFECKVCGSTFQTILRESVASGCPKCEHDRLGILADHLPEPDKN
                     SCLNNRKKPVTVMAMGFLCI"
     gene            1477..1785
                     /locus_tag="ACG8ZV_002792"
     CDS             1477..1785
                     /locus_tag="ACG8ZV_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998041.1"
                     /translation="MKEMKMKQVIYPVIIGVLAIALIILGVNCYNLSKENNQLETKNN
                     KQEIQIAKQAYVISDYKTYFRENYVDTVKYRSHFTDKQILNVYREALRDGKISDEGAN
                     "
     gene            2090..2368
                     /locus_tag="ACG8ZV_002793"
     CDS             2090..2368
                     /locus_tag="ACG8ZV_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998042.1"
                     /translation="MEKKEDLLNAFKNLDEKDQLKALLRLHDITYSDIAERLTVKKGE
                     REGQKGVSLVTVQKAFQSKTNLESDRWKEIVKVATKLIEERQNDQNKA"
     gene            2499..2708
                     /locus_tag="ACG8ZV_002794"
     CDS             2499..2708
                     /locus_tag="ACG8ZV_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998043.1"
                     /translation="MIRKLNNIKLSLAILTLFFGIYNNSRMALFFLTLLIFMNLIIHN
                     FKELENTAPAPSQGNQESEGMPHAW"
     gene            2698..2970
                     /locus_tag="ACG8ZV_002795"
     CDS             2698..2970
                     /locus_tag="ACG8ZV_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998044.1"
                     /translation="MLGSFKKDKEVKTRGALTPSQQNKLGTKATFHPVRDQANQKELI
                     GVCVGFTSEKFFPIIECKIHGITTREVARKVVKWHTSQTKTNHKKR"
     gene            3018..>3211
                     /locus_tag="ACG8ZV_002796"
     CDS             3018..>3211
                     /locus_tag="ACG8ZV_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998045.1"
                     /translation="MNNKNTKNTNTNHEKRSFFDKLFKKKKNGKVSILKMIGWIFLAF
                     FIVAVNSSGGDKKEAASKDTT"
BASE COUNT         1212 a          577 c          647 g          775 t
ORIGIN      
        1 taactatggt agatagtaac ggcaagccta tcttaaacaa atatggaaag ccgaaaaagg
       61 tagtaaaaat gccgatagat aactcggtta ctttgagtat tcagcgccta cggcacctag
      121 caagcttagg aaacgaaagc aacaaacaaa tagttgatcg ttacttttca aaccagccag
      181 aacctctgac aattaacgag caaatggaat tactccaaac ggggataaat ttacactcta
      241 tttatatggt agatgaaaat gaaaatgaga tcataaccgc gcccgctata gcaaggtggg
      301 taataaataa gcatacgcta gaagtaacag cgcggatcaa tccagaatat ttagagtggt
      361 tttcagaagt ggttaaccaa tacattttat ttaatctaag agactttgtg aagttaaaaa
      421 gtaagtactc catgatcctt ttcttagagc tttctacctt ttggaataca ggaatgtatt
      481 ataaaaggat taatgattta agagaaattt taggagtcaa tccaacgaga aataacagag
      541 attttataaa caacgttcta aagcctgcta tcgctgctct caaagagtac tttccagagc
      601 taagcctaac agtggaaaag aattctagcg actccagaaa gatcactcat gtaagattga
      661 agtttgataa gctaacaata accgatatgc aagaacgcct aagaagcagc gagggagctt
      721 ctttagtaga gtaccaacaa gagttggaaa atatggaagg agaggaaaaa gctgtcaacg
      781 atccaactcc agagatcgac ctttccaacg tggaatggta acacctgtca gcaatctaat
      841 ccaataaacc aaagtacttg taaggcgcga gggctccttt tagagccttc tagtcctata
      901 ccaaaccaag caaaataaag gagctataac caacatggaa aacactaacc aaacaccaaa
      961 tacagcacca actaaccaaa ctagcccagc cgaacgcaaa gccgatctta ttagattgta
     1021 ctcacgcctt gaaggtatga aactccaaca cgttccgacc gctccaaagg cgccagacgg
     1081 cttcccaaaa tcggcagaga gccttgagtt tttcgagtgt aaggtgtgcg gatcgacttt
     1141 tcaaacgatt ttaagggaat ccgttgcgag tggctgcccc aaatgtgaac atgatcgctt
     1201 aggaatttta gccgatcatt taccagaacc agacaaaaac agttgtttaa ataatcgaaa
     1261 aaaacctgta accgttatgg ctatggggtt tttgtgtatt tgagataatt tccaagggtt
     1321 atttatggat ttattttaaa aaatctatta aattatacta ccactggtag taatataaat
     1381 atatcgaaag ggtacgaggg ttaaagcgta atggcggaat gagtaccgtt ctcttttgaa
     1441 aataccaaac caaccaatta aaggagagaa agtaatatga aagaaatgaa aatgaagcaa
     1501 gtaatttatc ccgtgattat tggagtttta gctatcgctc ttattatcct tggtgtaaat
     1561 tgctataact taagcaagga aaataatcaa cttgagacca aaaacaacaa gcaagaaatc
     1621 caaatagcca agcaagctta cgttatcagc gattacaaga cttattttcg tgaaaactat
     1681 gtagacaccg tgaaatatcg ctcccacttc actgataaac aaattttaaa tgtttatcga
     1741 gaagctctta gagatggaaa aatcagcgat gagggagcta actagtggaa gagctcattt
     1801 tgctggctat gttattacag gaaaagaagc gtgaacgaga agcctaacag ctggaaagaa
     1861 tccgaatagg atatgaggaa gcagatcggg aaagagatca gaaaatagag gagctggaga
     1921 agcgtatcca agaactttcc aaaaactatg ataataacca agattgggaa caagagtggc
     1981 ggaaaatcgt tggtataaag gaaaatgaat acttagtgag aaagccgcca gaagaagagg
     2041 aagacccttg gagcgatttc taactaaaaa tcggaaggga ggtggtaagt tggagaaaaa
     2101 ggaagattta ttgaacgctt ttaagaacct agacgagaaa gatcaactta aagcgttatt
     2161 aaggcttcat gatataacat acagcgatat tgctgaaaga ttaaccgtta aaaaaggcga
     2221 gagggaagga caaaaaggtg ttagcctcgt gactgtacaa aaagctttcc aatcaaagac
     2281 caacttggag agtgatcgct ggaaagagat tgtaaaagtc gctaccaagc taattgaaga
     2341 gcgacaaaac gaccagaaca aagcataaaa aaagcccgtc catttaccgc tgaccaaagc
     2401 aataaaatga acgagccaca ccatttactt ttaggggtaa ccacacgccc taaaagctac
     2461 caaaccattt accaaataac cactaaggag atttagaaat gattagaaaa cttaataata
     2521 tcaagctttc tttggcaatt ttaacactat tttttggaat ttacaataat tccagaatgg
     2581 ctttgttttt tcttacgtta ttgatattca tgaacttaat tatccataat ttcaaggagt
     2641 tagaaaatac agctccagcg ccctctcaag gaaaccaaga aagtgagggc atgccacatg
     2701 cttggtagtt ttaaaaagga taaggaagta aaaacacgag gagcccttac accaagccag
     2761 caaaataagc ttggtacaaa agccactttc caccccgtcc gagatcaagc caaccaaaaa
     2821 gaactaattg gcgtttgtgt agggtttact tcagagaaat tttttccaat aatagagtgc
     2881 aaaatacacg ggatcacaac tagagaagtt gctagaaaag ttgtgaaatg gcacaccagc
     2941 caaaccaaaa ccaaccataa gaaacgttaa aaacgttcct aagagcgttt gaaaattaaa
     3001 ttaagggaga tttaagaatg aacaacaaaa acaccaaaaa taccaatact aaccacgaga
     3061 agagaagctt ctttgataag cttttcaaaa agaagaagaa tggaaaagta tctattttga
     3121 aaatgatcgg ctggatattt ttagcctttt tcatagttgc tgtgaacagt agcggcggtg
     3181 ataagaaaga ggctgcttca aaagatacca c
//
LOCUS       DAZULR010000120         3101 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.127, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000120 DAZULR010000000
VERSION     DAZULR010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3101
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.127"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(367..729)
                     /locus_tag="ACG8ZV_002797"
     CDS             complement(367..729)
                     /locus_tag="ACG8ZV_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998046.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(803..1183)
                     /locus_tag="ACG8ZV_002798"
     CDS             complement(803..1183)
                     /locus_tag="ACG8ZV_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvfD/Ygs/GSP13 family RNA-binding
                     post-transcriptional regulator"
                     /protein_id="HFS4998047.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1265..2440
                     /locus_tag="ACG8ZV_002799"
     CDS             1265..2440
                     /locus_tag="ACG8ZV_002799"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HFS4998048.1"
                     /translation="MIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADMDFLSPG
                     GVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVLTSLAAA
                     VQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDMEKKIEEN
                     NVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHTFTSMLT
                     IDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEINTFGLI
                     GTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLDFTAYIS
                     DDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYALETID"
     gene            complement(2516..3100)
                     /locus_tag="ACG8ZV_002800"
     CDS             complement(2516..3100)
                     /locus_tag="ACG8ZV_002800"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFS4998049.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
BASE COUNT          966 a          591 c          511 g         1033 t
ORIGIN      
        1 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcgt
       61 tagtaacatg tcaataacta ttttttaaat tttttagaaa tgtgatataa catccacttc
      121 agaatcaacg ctgttaaatt tatcatgtat ttcttccttg gtcaactata aattaagcat
      181 tactttgtga aatgattttt cgatcaatta ttattattcg ttatacaacc gttttcaaca
      241 tattttgaaa ataaaatgca ctaaaaaact atctttagca gaacatttca ttgtattttt
      301 tggaccaaac aataaaaaaa gaagtttgaa aaaaattcaa acttctttgt tcgcttaatc
      361 tgtattttag aagaaaggca ctccctctac ttcgtaagtt ccaagaacag agcgcatttg
      421 acctggttct tcccaaatat atccttcgcc taattcttct ctttgattct tttgttcagt
      481 ttcaaagaca aacaacggaa cattttcctc tttaatatgt gtatttgtca attccatcaa
      541 actaatcttg ctaacatcga tatgaactat ttcttttaag aaattaagta tattcgctaa
      601 accagtcttt ccttcagaaa gttccgctaa cgcaaattcc aacttgtcat caattgaatg
      661 gaccaaaaat tttttagtac catcctccaa atgcaacata attgtaccag caactctttt
      721 gcttgccaaa atttccacct cgatcaactt gttctatggc ttacataaaa attctagcac
      781 attttcagaa aaaatacact ttttatttct tattttcttt ccgttctagt tcagataatg
      841 cttcttctat ccaaataggt aactgctccg caatagtggt aaatccgatc ttacgatttt
      901 tattcgtgaa ataccttttt ctgcgatatg gaacagctgg atttgttttt tctaacgttc
      961 ttaaagataa actgattttt ttggaatatt catcaatgtc gatgatctga actgttactg
     1021 gctgtccgac ttttaacaat gaatggatat ttttcgtata accggattgt acttctgaaa
     1081 catgaataag tccttgcgtc tcgttatcaa gagaaacgaa tgcgccataa ggctgtatcc
     1141 ctgtcacttt tccttcaatt atttgtccaa ttttataagt catctacttc cctctcttcg
     1201 catttatcat tatactgtaa atagctcaaa aaaagaagcg acgaaaatga ctggaggtct
     1261 taagatgatc gaatttgata aacagatttc aagaaaagat acagaaagtg taaaatggga
     1321 cgcaattgct gagacatatc aaatggatga cttacttcct ttgtgggtag cagatatgga
     1381 cttcttgtct cccggtgggg tagctaaagc gtttagtgaa tacatcaaac atggaatctt
     1441 tggttatgcc actctgtctg ataaactata tcaggctatc attcattggg aacgccaaca
     1501 ccatgctgtg gagttgacga aagaaaatat cgtttttaca agtggtgtgt taaccagttt
     1561 agctgcagca gtacaaactt ttacaaaacc aggcgattct attttgattc atgacccagt
     1621 ttatcctcca ttttcctcta ttatagaaac aaatcaacgt cacatcgttc gaagctcttt
     1681 gctagaaaaa aataatcatt tcatcatgga cttgtctgac atggagaaaa aaatcgaaga
     1741 aaacaatgta aaagcaatga ttttatgcaa tcctcacaat cctggagggc gtgtttggag
     1801 caaagaagaa ttgaaacagt taagcgaatt gtgtttaaaa catcaagtga ttctgtttag
     1861 tgacgagatc catcaagatt taactttatt cgatcataca tttacttcca tgctaacgat
     1921 tgatcctaat ttagatgatc tactagttgc ttttacttcc gcaaccaaga ctttcaatct
     1981 agctgcaatc aaaaattcaa tggtatttat caaaaatcca gagatgaaag ctgattttga
     2041 aaaacattta gtgatgaacc aacagcacga aatcaacact tttggactga ttggaaccca
     2101 agcggcttat gagacgggtg gagaatggtt aagccaactg attccttatc tagaaaaaaa
     2161 tgttcaaaca gttaatcagt tttttgaaca gtatcttccg aaagtgagaa taatgaaccc
     2221 tgaaggaact tacttaatgt ggttagattt taccgcctat atttcagacg accaagaatt
     2281 ggagaacact cttgttcgga aaggaaaagt cgtattaaat cctggcatca cgtttggtcc
     2341 ttccggtcat gggcatatgc gcttgaatat tgcttgtcca gaagaaactt tactggaagg
     2401 acttaatcga atcaagtatg ctttagagac aatcgattaa atatttattc aaaataaaag
     2461 gacgagacct tactaggttt cgtccttttt cataattact ccgtaccata ccaaactatt
     2521 ctgaaatttc aattgtttca atcactacat catgtacagg tcggtcttgt ggaccacgtt
     2581 gtacatttgc gatttcatct actgtgtcca tcccttctag tacatgtcca aagactgtat
     2641 gtcggaaatc tagccaagga gttccgccac ctttatacgc ttcaatgatt tctgatggga
     2701 atccagcacc ttctagttgt ccaagcatat tagctggcac atttgtgtta tttacaataa
     2761 agaattggct tccgtttgtg tttggacctg aatttgccat agataaagct ccgcgaaggt
     2821 tgaacagttc acgactgaat tcatcttcaa aactttcgcc ataaatactt tcgccaccca
     2881 ttcctgttcc agttggatcg ccgccttgga tcatgaaatc aggaataacg cggtgaaaaa
     2941 tcacgccatc ataataacct tttttggaaa gttcaatgaa attttgaacc gtcttcggtg
     3001 ctagttcagg gaataattga acagtaatgt caccacggtt tgttttgata acagcttttg
     3061 gtcctttttc actttttaaa tctagttgtg ggaatgccat a
//
LOCUS       DAZULR010000121         3011 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.128, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000121 DAZULR010000000
VERSION     DAZULR010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3011
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.128"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..182
                     /locus_tag="ACG8ZV_002801"
     CDS             <1..182
                     /locus_tag="ACG8ZV_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998050.1"
                     /translation="FVYRHVNLFAEPLFVLYESNSSIVSELANLMIALLFTPALRVIT
                     ILVCLVLLFFVNKKK"
     gene            complement(366..1115)
                     /locus_tag="ACG8ZV_002802"
     CDS             complement(366..1115)
                     /locus_tag="ACG8ZV_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFS4998051.1"
                     /translation="MLKLERHQKILDLLNAEQKVIASDLSQRFNVSEDTIRRDLKDLD
                     SQGLLKRVHSGALRVGPPITNFNYRETVASEQKTALAHKALPFLKEESVIIIDGSTTN
                     LALAKEIPQDFRATIITNSPPIAIALAQHPNLEIINIGGTFYKQSMINIGVQAYKQLQ
                     NIRADLYIMGIYNIDLDVGTSVPTMQESDIKREMIRISTEVLGMITNDKFGTISNHIV
                     GPIEDLTYLISEEIPEKVRKEYNKQKIVLID"
     gene            1301..2005
                     /locus_tag="ACG8ZV_002803"
     CDS             1301..2005
                     /locus_tag="ACG8ZV_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HFS4998052.1"
                     /translation="MEKKIILSPSLMCGDLANLEGSIQELESIGMDSLHIDVIDGSFS
                     PSMPLGIETIKRIREITSMNFDVHIMAKDNDNEFFIGEMLKIGVESITFHYETSLHID
                     RYIQLIKNSGTKVGIALNPATPLNVLQYILPEIDRICLMLINPGFATNKSEKQVSYAL
                     KKITDLCQLVNEKELAVDIQVDGRVSLETIPGLLDAGATNLVLGSTSLFLKGNTLAEN
                     QKLLYQAMKQSVRKNQ"
     gene            2045..2602
                     /gene="hxlB"
                     /locus_tag="ACG8ZV_002804"
     CDS             2045..2602
                     /gene="hxlB"
                     /locus_tag="ACG8ZV_002804"
                     /EC_number="5.3.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_function: GO:0043800 - hexulose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-3-hexuloisomerase"
                     /protein_id="HFS4998053.1"
                     /translation="MSYKAAKQNIVREITETLDRISSKDVEQLIKKIEKAERVFFVGV
                     GRVLLALEGMAKRLGHLGIQTVVVGQITEPAITDKDLLIVGSGSGESAFPLTIAKKAK
                     EFGSQVAHIGSNPDSTMKEYSDLFIRIPVQTKLALPEEISSIQPMTSLFEQSVLLLGD
                     SIALVMIEEKAIDMSKLWQYHANLE"
     gene            2610..>3011
                     /locus_tag="ACG8ZV_002805"
     CDS             2610..>3011
                     /locus_tag="ACG8ZV_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HFS4998054.1"
                     /translation="MKAVHFGAGNIGRGLIGQILHQNGFDLCFIDTNPELIHQLNQDK
                     GYTIEIIDEMNRSDFIDHVVALNSLSELEEVITATKNADILTTSVGAINLVKIAPIIA
                     QALSKRFEQKHSINIVANENVINASDVLKKEI"
BASE COUNT         1001 a          441 c          607 g          962 t
ORIGIN      
        1 aatttgttta tagacatgtg aatttatttg cagaaccttt atttgtatta tacgaatcaa
       61 attcctcaat cgtcagtgaa cttgctaatt taatgatagc attgctgttt actcccgcgt
      121 tgagagtcat aactattttg gtctgtttag tgctattgtt ttttgttaat aaaaagaaat
      181 aacgtagtat ttcaaaagac aaagaagtgg gatgatgatt gctatagtat gttatacgtg
      241 gtgctaggta agtgagaata aacaaaaaag gaaacacgca ataaagttta tttcaaaact
      301 ttattgcgtg tttctttttt agatttttta tatctgttgc tttagtagtt accaatagtt
      361 ttcgcttaat caatcaaaac gattttttgt ttattgtatt ctttacgaac cttttcagga
      421 atttcttctg aaataagata ggtaaggtct tcaattggac cgacgatatg attactgatg
      481 gtgccgaatt tatcattagt tatcatccca agtacttcag tagaaatacg tatcatctca
      541 cgtttaatgt cggattcttg catagttggc acgctcgttc caacatctag atctatgtta
      601 taaataccca taatataaag gtcggctcga atgttttgta gttgcttata agcttgtacc
      661 ccaatattga tcatagattg tttataaaaa gtaccgccaa tattgataat ttccaaatta
      721 ggatgctgtg ctaatgctat ggcaatcggc gggctattgg taatgattgt tgcacgaaaa
      781 tcttgtggga tttcttttgc taaagccaag ttagttgtac ttccatcaat gatgatgaca
      841 gattcttctt ttaaaaaagg gagggcttta tgagctaatg cagttttttg ttcgctagct
      901 acagtttctc ggtagttaaa attggtaatt ggcggaccaa cacgtaaagc gccgctgtgt
      961 actcttttta agagaccttg gctatccaaa tctttcaaat ctcgtcgaat cgtgtcttcg
     1021 gatacattga aacgttgact taaatcacta gcgataactt tttgttctgc gtttaataaa
     1081 tctagaattt tttgatgacg ttctaatttc aacatgttgc gtgctccttc ttatttattc
     1141 ttgtttatca tgtcatttat gcgtttttat gtcaataatt tccgttttta atacactaaa
     1201 aaggcataaa caagcaaaaa caaaatattt ttatgcagtt ttatgttgac tagtatttgt
     1261 taagcggtta caatgagggg gtaattaaag gagggaatgt atggagaaaa aaattatttt
     1321 gtcgccttca cttatgtgtg gggatctagc aaatttggaa ggaagcatcc aagaactaga
     1381 aagtattggg atggattcct tgcatattga cgtgattgac ggttctttta gtcccagtat
     1441 gcctttaggg atcgaaacaa tcaaaagaat tagagaaatc acttcaatga attttgatgt
     1501 acacatcatg gctaaggata acgataacga attttttatt ggagaaatgt tgaaaattgg
     1561 cgtagagagc attacttttc attatgaaac aagcctccat attgatcgat atatccagct
     1621 catcaagaat tctggaacaa aagtagggat agctttgaat ccagcaactc cgttaaatgt
     1681 attacaatat attttacccg agattgatag gatttgtttg atgctgatta atccaggttt
     1741 tgcaacaaac aagtcagaaa aacaagtttc ttacgcgcta aaaaaaatta cagatctttg
     1801 ccagttagta aatgagaaag agttagcagt agatatccaa gtggatggac gggtatcgtt
     1861 agaaacgatc ccgggattat tagatgcagg cgcaacaaat ctggtattag gaagtacaag
     1921 tttgtttctt aaaggaaata cattagcaga aaatcaaaaa ctactttatc aagcgatgaa
     1981 gcaatcagtt aggaaaaatc aatagatgta gtggtcctga ataatagaaa tggaggggaa
     2041 atagttgagt tataaggcgg cgaaacaaaa tattgtaaga gaaattactg aaacattaga
     2101 ccgtatttct tcaaaagatg tggaacaatt gataaagaaa attgaaaaag cggaacgagt
     2161 ttttttcgtg ggggttggca gagtactgtt agcgctagaa ggaatggcaa aacgcttagg
     2221 gcatctagga attcagacag tagtcgtagg acaaatcact gaaccggcaa ttacagataa
     2281 agatttattg attgttggtt ctggtagtgg ggaaagtgct ttcccactaa ctattgcaaa
     2341 aaaagcaaag gaatttgggt cccaagttgc ccatatagga tcaaacccag acagcacaat
     2401 gaaagaatat tcagatcttt ttattcgtat acccgtacaa acaaaattag cgttaccaga
     2461 ggaaatttct tctatacagc caatgactag cctgtttgaa caaagtgttc ttttgttagg
     2521 agatagtatt gctttagtga tgatagaaga aaaagcaatt gatatgtcaa agttgtggca
     2581 ataccatgct aacttagagt aggtgaaaaa tgaaagcggt acattttgga gcagggaaca
     2641 tcggcagagg gcttattgga caaattctac atcagaatgg attcgatcta tgttttattg
     2701 atacgaatcc tgaactgatc catcaattaa atcaagataa gggttatact atcgaaatta
     2761 ttgatgaaat gaacaggagt gatttcattg atcatgttgt ggcactgaat agtttatccg
     2821 agctagaaga ggtgattaca gcaacaaaaa atgcagatat cttaacaaca tctgttggcg
     2881 caataaattt agtaaaaatt gcaccgatca ttgcgcaagc cttaagtaag cgatttgaac
     2941 aaaagcatag catcaatatc gtagctaatg aaaatgtgat aaatgcaagt gatgtgttga
     3001 aaaaagaaat t
//
LOCUS       DAZULR010000122         3007 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.129, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000122 DAZULR010000000
VERSION     DAZULR010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3007
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.129"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            681..>3007
                     /gene="esp"
                     /locus_tag="ACG8ZV_002806"
     CDS             681..>3007
                     /gene="esp"
                     /locus_tag="ACG8ZV_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HFS4998055.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKYFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAG"
BASE COUNT         1100 a          452 c          582 g          873 t
ORIGIN      
        1 tttttcagaa aagttaaaca actacaagtt aatagattat aagtatttga gtgaaagcaa
       61 ttaattattc atgtagagta ctagacactt taaatatgga caattcaatt ataaagaaaa
      121 agaatcaata atttaatgag gctgtgacaa atgtcatttt ttgtttcgct aaaaacgagt
      181 gaaaaaatgt tgataactcc aatcattcgt ttaagattct aggaatcatt cagaaatgct
      241 gtgaaaccga tactttataa ttataaagaa ggtgatttca aattccgaag aaggaatttg
      301 aagtcacctt tttacttatg tcacagtctc attcagtaat gcgggataag gctccttatt
      361 ccgttatttg aatactctga agtttaatct aagaaagggt aatattttga aaacatgctt
      421 catcgcatag aaatgaactt aatttcagaa agaatacata catatctttt tatatgtttt
      481 cagctgctga atggttaaaa agcacaaata tccgaaaaaa acatgaagaa atgtactttt
      541 tttgttgtaa tgttcatgaa attctctaag taaattagtt aacataaggt tagtaagatt
      601 cctattctgt gaataatacg tatcagattt atcttttatt cttactagga aagtaattat
      661 taagggagtt gatttgaata atggttagca agaataataa gagagtattt ctagaaaaaa
      721 caaagaaacg agtattgaag tacagtatca aaaaattaag tgttggggtt gcatctgttt
      781 tgattggtgt tggtcttgtc ttgggaacaa ctgaactagt taaagcacaa gatgaaattt
      841 ctccaagcag cccacttgaa acagcgataa gctccgtaca agtaggtgac aaagtagctt
      901 cggggaatac ttttcaggag aatcctggtt atacgaaaaa ttataacttt tcggatttac
      961 aatttagtcc tcaagaacta actggagaca cactaaaagg caatacaatt ggatttgaag
     1021 tttacggaaa acataatatt gcagcatcaa ctaaaaactg ggaaatccgt cttcaattag
     1081 atgaacgatt agctaaatat gtagaaaaaa ttcaggtcga tccaaagaaa ggaattggat
     1141 cttctagacg gacctttgta agaattaatg attcgctggg tagacctaca aatatttgga
     1201 aggtcaatta tattcgtgca agtgatggat tatttgctgg ggcagaaaca accgatacgc
     1261 aaaccgctcc taatggggta attacgtttg aaaagagcct agatgaaatt tttaaagaga
     1321 taggcataga caatctcaag accgatcgtt taatgtatcg aatctacttg gtaagtcatc
     1381 aagacgatga taaaattgta ccgggtattg atagtacggg ctacttttta acagattcag
     1441 atgatttcta taatagctta gatgtatctg aaaataatcc tgaccagttt aaacatggat
     1501 cagtaagtgc aaaatatgag aaacctaata ctcaaacaaa agatggttca ggatccacag
     1561 gtgctaatgg agctataatc ttagatcata agttaacgaa aaattataat ttctcatatt
     1621 catcttccgc aaagggcacg ccttggtatg ctaattacaa aattgatgaa cgattagttc
     1681 catatgtagc gggtatacag atgcacatgg ttcaggctga caaagtaaca tatgatgttt
     1741 cgtttgaatc cggaacaaaa gtagctgatt tagcaatcga gcgacgggaa ggtcatgaaa
     1801 attatggcat aggttcaata actaataatg atttaactaa acttatcgat tttgctaatg
     1861 caagtccacg tccagtcgtt attcgatatg ttttacaatt gactaagcca ttagatgaaa
     1921 tcttagaaga tatgaaagca acagcacaag ttgaagaaaa taaaccattt ggtgaagatt
     1981 tcatctttga ttcttggttg tcggatacga ataaaaaatt aatccagaac acttatggaa
     2041 caggttatta ttatttgcaa gatattgatg gtgatggaaa ccctgacgat aaagaagaga
     2101 gcggagacac gaatccatat atcgggaaac ctgaattaga agaagtatat gatgttgaca
     2161 caacagttaa ggggaaagta ttcatccacg agttagcggg aacaggtcac aaagcccaac
     2221 ttgttgataa agaaggtact gtattagcag aaaaaactat cgctccaaat gaaaaagatg
     2281 gggctccaat ttcagatact gtagaatttg aatttacggg tgtagattca agtaaattaa
     2341 tcgcgaaaga tgaattaaaa atccaaatcg tttctccagg ttttgataaa ccagaagaag
     2401 gttcaaccgt tattaaggaa tcaccaaaag cggttgataa acaaaccgtg gtagttggat
     2461 ttaaaccaga tgctaaagaa tcaattcgga ataataaaaa cttacctgaa gatgcagagt
     2521 attcatggaa aacagagcct gatacttcta acgttactga tagtacgaaa ggtattgtaa
     2581 ctgttaagat cggaaatcga actttcgacg tggatgtaga gtttgctgta aaagcttctc
     2641 aagctatgga aaatgatgca acatacgtac ctataacaac aactccagaa acgacagttc
     2701 aaagtggaaa acctacattt gataaaccag atgttccttt agctaaagat gccttttcaa
     2761 tttcagatgt ctataataag tacttcggta atgcaagtgt tgatgcaaac actggtattg
     2821 ttacattcac tccagctaaa ggtgtaggag aatcggagcc gattactgga acaattccta
     2881 ttaaaattgt ttaccaagat ggttctgtag gcacgaccga tttagcagta actgtaagta
     2941 aagatattta tgaaaatcca ggagaaaaca ttcctgcagg ctaccacaaa gtaaccttca
     3001 ccgcagg
//
LOCUS       DAZULR010000123         2911 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.130, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000123 DAZULR010000000
VERSION     DAZULR010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2911)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2911)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2911
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.130"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1470
                     /locus_tag="ACG8ZV_002807"
     CDS             <1..1470
                     /locus_tag="ACG8ZV_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rib/alpha-like domain-containing protein"
                     /protein_id="HFS4998056.1"
                     /translation="DTVKVPVEVTDNRSDADKYEPTVEGEKVEVGGTVDLTDNVTNLP
                     ALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSDADKYE
                     PTVEGEKVEIGGTVDLTDNVTNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYP
                     DGTKDTVKVPVEVTDNRSNADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYAW
                     KEKVDVSTAGNKKGTIVVTYPDGSSDEVEVDVTVTDTRSDADKYNPEGQKVTTDLNKE
                     PDASEGIKNKEDLPKGTTYTWKEKVDVSTAGNKKGTVVVTYPDGSKEEVEVTISVVDK
                     KAPNKPQVDPITEGDQIVTGKTEPNAEVTVTLPDGSQHHGTADKNGNFTVKVPKLEAG
                     TKVIVTATDESGNTSEPTNVVVSSNKKDSGKNGSKGSKTDNQGSNSNQDKNRGKSQSS
                     KVFPKTGESDSNIFTISGGLILLGTLGLLGYKNRKKENE"
     gene            1604..>2911
                     /locus_tag="ACG8ZV_002808"
     CDS             1604..>2911
                     /locus_tag="ACG8ZV_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFS4998057.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFI"
BASE COUNT         1139 a          401 c          573 g          798 t
ORIGIN      
        1 gatacagtga aagttccagt agaagtgaca gacaatcgtt ccgatgccga taaatatgaa
       61 ccaacagtag aaggcgaaaa agtagaagtt gggggcacag tagatctaac agataatgtt
      121 actaacttgc cagcgttacc agaaggaaca acagtaacag atgttactcc cggcggtaca
      181 attgatacca acacaccagg taattacgaa ggtgtcattg aagtaacgta tccagacggt
      241 acgaaagata cggtgaaagt tccagtagaa gtgacagaca atcgttctga cgccgataaa
      301 tatgaaccaa cagtagaagg cgaaaaagta gaaattggag gcacagtaga tttaacagat
      361 aatgttacta acttgccagc gttaccagaa ggaacaacag taacagatgt tactcccggc
      421 ggtacaattg ataccaacac accaggcaat tatgaaggtg tcattgaagt aacgtatcca
      481 gacggtacga aagatacggt gaaagttcca gtagaagtga cagacaatcg ttctaatgca
      541 gataaataca atcctgaagg acaaaaagtg actacagact taaataaaga gccagatgca
      601 tctgagggaa ttaagaacaa agaagattta ccaaaaggaa ctacttatgc ttggaaagag
      661 aaagtagatg ttagcacagc tggaaataaa aaaggtacta ttgtagtgac atatccagat
      721 ggatcatctg atgaagttga agtagacgtt acagtgacag atactcgttc cgatgcagat
      781 aaatataatc ctgaaggaca aaaagtgact acagacttaa ataaagagcc agatgcatct
      841 gagggaatta agaacaaaga agatctacca aaaggaacta cttatacttg gaaagaaaaa
      901 gtagatgtta gtacagctgg aaacaaaaaa ggtactgtag tagtaacata tccagatgga
      961 tctaaagaag aagtagaagt tactatttct gtagtagata aaaaagcacc gaataaacct
     1021 caagttgatc ctattacaga gggtgaccaa attgttactg gtaaaactga accaaatgca
     1081 gaggtgacag ttacattacc agacggaagt caacaccatg ggacagctga taaaaatggt
     1141 aattttacag ttaaagttcc taaattagag gcagggacaa aagtgatagt aactgcaact
     1201 gatgaatctg gtaatactag tgaacctact aatgtagttg tttcttccaa caaaaaagac
     1261 agtggaaaaa acggtagtaa aggtagtaag actgacaatc aaggtagcaa cagcaatcaa
     1321 gacaaaaata gaggcaaaag ccagtcctca aaagtttttc ctaagacggg agagagtgac
     1381 agtaatatct ttactattag cggtggttta atactgttag gaacgttagg attattaggg
     1441 tataaaaatc gaaaaaaaga gaatgaatag aaaatcaatt tcttaagtct tctctgagaa
     1501 gaggaagaat ctttttcttc ctctttttgc ttttttatga tgggaaataa gtgttagtta
     1561 aagatgaata tactttttat agaaaggaaa agaatgtaat taagtggaaa aaatagtaat
     1621 tattggttca aaccattcag ggctagccgc agctcgattt ctaaacttaa gcgattcaaa
     1681 ttatgaagtt attctaatcg ataaaaaatc agaaattagt tacttggaat gtgggacatc
     1741 gttatttata aaaggagaag taagtaattt agaagatctt ttttatcaaa atagaatgac
     1801 actaaattct gagataaaaa agttatttct agagacagaa gttgacaaaa ttgatattca
     1861 aaataaaaag attagttgtg taaaaaaaga tggtacaaga ttctctcaag aatatgacaa
     1921 agttatatta gctacaggtt caaagcaaat tatgctagat ataccgggga ataatttagc
     1981 taatattttt tcgataaaga attttccaaa tgcaaaagag atttttaaag ctttggatga
     2041 tagtactatt aaaaaagtag gaattattgg agcaggatat attggagttg aaattgctga
     2101 agccataaga aaaagaggga aagaagtata tcttttcgat gttgcagata gagtgttgtc
     2161 gacttattac gaccgtagtt tttcagataa agttgaagaa atactatcaa aaaatggaat
     2221 acatctttgt ctatcagaaa gtcctaaaaa atatttagga agaaaaaaga ttgaaaaaat
     2281 agtcactaca agtggtaccc aatactctat ggatatggtc gtacaagcta taggatttct
     2341 atctaatagt ccaattgggg aaaaggaact cttgagagat gttagtggag catatctaac
     2401 taatgaatac cagcaaacaa atataaaaga tatatatgct attggggatt gtgctacaac
     2461 tttttttacg tccattaata gaagtagtgt tgatttttct atttctaatg ctctaagaac
     2521 agcttatatt gcaactcaac atattaacaa tcaagatttt acaccttctg gttcccaatt
     2581 tacaaatggc ttttctatat ttaattacaa tttttacgca gcaggtttga atttaaaaac
     2641 agcacgatta ttaagtgagt ctatagatta tatagaaata gaagatttca ttagacctgc
     2701 ttttttgaga aaaaatagtc gtgtaaaatt aagaattagc tttgaaaaaa atacaaagag
     2761 aatagtaggt gtacaacttt gtagtcaaga agatttatct ggactattat caatgttttc
     2821 tcttgctata gaagaacaaa ttacattaga caaattgaaa atgttagatt atttatttca
     2881 tcctagtttt agccaaccct ataattttat t
//
LOCUS       DAZULR010000124         2719 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.132, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000124 DAZULR010000000
VERSION     DAZULR010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2719
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.132"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            700..2610
                     /gene="ltrA"
                     /locus_tag="ACG8ZV_002809"
     CDS             700..2610
                     /gene="ltrA"
                     /locus_tag="ACG8ZV_002809"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFS4998058.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
BASE COUNT         1065 a          420 c          556 g          678 t
ORIGIN      
        1 aaaagctaag gcactaataa aagaacgaaa aagtttggtt attaggagaa ctgataatct
       61 gacaggtgga atgatgaagt aacgctctga aacgcctgcc ctgagcctcc gacaagcatt
      121 gtatgaggaa actcagaatg tttgaagctc ggtaaagacg gctgaaagat accgtaatag
      181 ttgatgaaca tatatcttct atcgaaaact atccagaggt gggtagcgta tccaacaggt
      241 cgggggtcta taaaatatct atggttagaa tgttctataa ggaactgacg aaacagcgaa
      301 tgtacgggtc taaatttgaa ctttgtagaa atgcaaaggt acgagaaatc gtagctggtg
      361 tggcaaagta agaatatagg ttatgaaatg ccatataacg ttacaggcgg tatcaagcca
      421 gcaggcttat agctagtgac ctaaggatat atatgtatag ataagattat cggaacgagg
      481 aaaggtattg ggttctcatc aagagaataa actgacgaag aacaataagc agttgaacta
      541 atgctgaaaa gcagagggcg aacctaagaa attcttgtaa tgagaatgga ggaatgccct
      601 caagtcgtgt atatattaga aaagtattat gttgtttcaa taaggattac gagtaagata
      661 aaaaagctca ctcaatttca agtaaaggag tgaagcctta tgcctaaaaa taaaaatgaa
      721 acattgtgtg tagaagattt aagacacgct gaatattacg aaatgcaaaa cacctttgat
      781 gatttatatg ccaaaagtaa gaatggagat attttcactc atcttatgga tattatccta
      841 tcgagagaaa atatattact ggcatatcga aatatcaaag caaatgcagg cagtaaaaca
      901 gcaggaacag acggtacaat aattaaagat attggcaaat tgccagcaga aacagttgtc
      961 aaaaaagtaa gatacattgt tgcaggcagt ccacatgggt atcgacctaa gccagtgagg
     1021 cgaaaagaaa taccaaaacc aaatggtaaa accagacctc taggtattcc ttgtatgtgg
     1081 gacaggctta tacaacaatg tataaaacaa gtattagaac caatctgcga agctaaattt
     1141 agtgaaaaca gctatggttt tagacctaat aggtcagttg aaaatgcaat aaaagcaacc
     1201 tataaccgcc tacaaatcag ccagctacat tatgtgattg aatttgatat taagggtttc
     1261 tttgacaacg tgaaccattc caagctgata aaacagatat gggctatggg aatacgggac
     1321 aagcacttga tattcatttt aaaaaggata ttaaaagctc caatcaaaat gactaacggt
     1381 acaataacat atccagagaa aggaactccg caagggggaa taatatcccc actactagca
     1441 aacattgttc ttaatgagtt agaccattgg gtagaaagcc aatggcagga aaatcctgtt
     1501 acaaaaaact atgtggttca tatcaataaa agcggtagcc catgtaaaag caacgcttac
     1561 aaagaaatga agaaaacaaa gttaaaggaa atgtatatgg ttcgttatgc agatgatttt
     1621 agagttttct gccgctacaa ggaaagtgct gaaaaagcca aaatagcaat cactcaatgg
     1681 attgaacaac gattaaaatt ggaagtatca caagaaaaaa caagaattgt aaatgttaga
     1741 aaaagatact ccgactttct tggtttcaag attaaaatga taccgagaag aaagaagtta
     1801 gttgttaaat cacatataag tgataaacaa ttcaaaaacc aaaaagacaa gctggtatca
     1861 caggcaaaga aaattgcttc tccctcaaaa gggaaaacgg aattagaaga aacaagactt
     1921 tataattcaa tggtattagg tatgcaaaat tattatcaga ttgcaacgaa tgtaaatctg
     1981 gattgtatga aactgaatag agctgtaatg gctatcttca ctaacagatt aggtacaaac
     2041 aaaaggggca gattgagaaa aacaggcaga caacttacga caaaggaggc aacaagatat
     2101 ggtaaatcta aaatgcttcg gtatgttgct ggcgagggcg aacctatttt ccctgttgga
     2161 tatatccaac acagaaaacc aatggcaaag gtgtatttag cgaattgcta cactctagag
     2221 ggaagaaaat ttatccacac caatctaagt gttgataaat tactgatgta ccagttaatg
     2281 aaattatctt tggaaaatcg cacaatagaa tacgcagaca atcgaatttc gctattttct
     2341 gctcaacatg gaaaatgtgc tataactctg gaagaatttc aacaagctaa tgaaatacat
     2401 tgtcatcata ttgtaccaac tggagctggt ggaaatgacg attataaaaa tcttattttg
     2461 gtaaaagagg cggtacaccg tctaatacac gctaaaacag aagaaacaat acaaaaatat
     2521 atagctctat tgaagctaaa taaagtccag ctcataagac taaataaata tagagtatta
     2581 gctggcaatc aagaattaaa cttgatatag gtctactaca taaatacttt tcaatataaa
     2641 cacgatggaa cgcggagtgc ggtgaaagtc gcacgctccg tgtgaatggg gggaaaagtt
     2701 tgagatattt ataatatca
//
LOCUS       DAZULR010000125         2485 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.133, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000125 DAZULR010000000
VERSION     DAZULR010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2485
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.133"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..301)
                     /locus_tag="ACG8ZV_002810"
     CDS             complement(<1..301)
                     /locus_tag="ACG8ZV_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6056 family protein"
                     /protein_id="HFS4998059.1"
                     /translation="MNKHNRKITNNKELILLLIGIWGIFLLFNMYMPTMRADDVVYAS
                     RLDELGYLGASIEHYKTWSSRIIIELFLMFFSKHFMLWKLLNSTIMLGIVVLLCKY"
     gene            394..743
                     /locus_tag="ACG8ZV_002811"
                     /pseudo
     CDS             394..743
                     /locus_tag="ACG8ZV_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741963.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(1015..1305)
                     /locus_tag="ACG8ZV_002812"
     CDS             complement(1015..1305)
                     /locus_tag="ACG8ZV_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998060.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1513..2205)
                     /locus_tag="ACG8ZV_002813"
     CDS             complement(1513..2205)
                     /locus_tag="ACG8ZV_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFS4998061.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT          734 a          459 c          349 g          943 t
ORIGIN      
        1 catacttgca aagtaatact acaattccta acataatcgt agaatttaat aatttccata
       61 gcataaagtg tttagaaaag aacattaaga atagttctat aataattctt gaactccatg
      121 tcttataatg ttctatcgaa gcacccaaat agccaagttc atctaatcta cttgcataaa
      181 ctacgtcatc cgctctcata gtcggcatat acatattaaa gagtaaaaag ataccccaaa
      241 tccctattag taacaagatc agttctttgt tattcgttat ttttctatta tgtttgttca
      301 tttttatact ccttcttata tttcctaata gagtataaca tagctttaag cattacttaa
      361 agataactta aaagttatct tttaaatact taattgttaa ataccttatt tgatgcaaaa
      421 gaaatctacg atagtcaaca aaaaaatttt cattatatcc agaaaaattt ttcttagtta
      481 aggacctatg gattgcagta atgcagaatt cgtcgaataa actgccaaag acatacaatc
      541 atattgcttt taaaattgac gaacaagata tagattcgtt tgtctcaaaa atccaaatgt
      601 taggtttaac tgtcgaacca ggacgttctc gtgtgaaagg cgaggcttct tcaatttact
      661 tttacgacta tgataatcac ctcttcgagt tacataccgg tactctccag gaacgtttaa
      721 aatcctacaa ttccactacc tgagactagt aatgactagt ctctttttat ggcctctgat
      781 ccccccattg agcgaatact aatagggctt cgaattgatc tgttcaatct ttaagcaata
      841 tccctcaaat gagtttggaa agtttagtga ttcatcacaa atacttaaat acatgtagtt
      901 atatatagat tgaggttctt gtgagcgtat gctcgtgtgg gttcaaatcc catcgtctgc
      961 atccatcttt ccaaaacaag cggctaggac atttttgtct cagccgcttg ttttctagtt
     1021 tattctttca tcttgtcgga ccttttttct tgggtataga cttttctcat attctaccac
     1081 aattttgggt ttccctaaca catgatagga tctcacaaca aattgctttc tattattata
     1141 ataacctgta acgactaact tcatcccttc gtctacttca gctaggaagt tcaaactatg
     1201 ggaagcaatc aaacaattga ccccatttaa actgaaacgg atcaacggtc tggcactaac
     1261 ttgcaaagta cggatcttat ctactgttcc atattttttc tccataacct tcacctcaat
     1321 accattatac gaacatacat tccctttgta aagaagaaac tctgttttat ctttttgact
     1381 ttttgtctat tacctttctt aaaatcatat tggcacttcc tgcgaagatg aaggacatgt
     1441 actaaaaaaa agaggcagca gtatagatta ctgttgcttc tttactaatt taggtttact
     1501 tgttaagaaa gattatttac gcaaatgttc ttcaacaatt tgctgagatt tatcagctgt
     1561 atcttccact tcatcttttg ctttttctaa cttttgaata tattgtttca agcttgagtt
     1621 ttcagcagtt gcttcgtcta atttcttttg tgtatctgtt aactgagttt ctacatttgt
     1681 tttttcttgt gtcagtgttg cgatttgttg attcaaacca tttacagtat tttgtaattc
     1741 tgaaagtttt gcttgtgctt cttgtagtct tgctgtccaa tctgcattca gatgattgat
     1801 ttcatcattt ttttggttga tctcatctag tttgacattg atttcatttt gtttgctttg
     1861 tagttgtgca tccttgctga ctaattgact ttctaagttt tgtttttctg ctgccgattg
     1921 atttttttgg ttttctaatt catttacttt tgtttggtat tcttggacat ctgcctttga
     1981 atcttgcaat gtctgttctt tttgtgctag tcgagcggta agatctgtaa tcgcttgctc
     2041 tttatctgtc aatgtatgat caagctgtgt cagattctca ttgattgtat caatatctgt
     2101 ctctccaccc cacaaaataa tttcatttgc gtaccgcgtg cctgtgtagc caattagaca
     2161 tagaaatgca acgacaatcc caccagtaat aaatttcttt ttcatttgca tagctcctta
     2221 atccaatact tttacatgct aaaagtaagt gatctcaaac acaatgtcaa gcgtttttaa
     2281 attacatatg taattttaat ataaatacta tcaaatactc atttaatcct ccttttttat
     2341 ctatttaaaa aatctttttt atagagaaaa atgcaggtta atactttctt aaataaatat
     2401 ttatggtgaa caaaaacaaa aaagcaagtt ttattaaacg taaccctttt catttcatag
     2461 attactgtat ttattacaaa aaacg
//
LOCUS       DAZULR010000126         2469 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.134, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000126 DAZULR010000000
VERSION     DAZULR010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2469
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.134"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..353
                     /locus_tag="ACG8ZV_002814"
     CDS             <1..353
                     /locus_tag="ACG8ZV_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998062.1"
                     /translation="ETRVPKKHYKERLSVAVEEMIESGVEMNLIATYYRTLEELKKQN
                     GQWFFQALLCLEAGVKPNTIKPSEYQALELTYGKFVETKKAKTVSSEWLDYLENVNKY
                     GACYIMKKEDNENE"
     gene            346..1041
                     /locus_tag="ACG8ZV_002815"
     CDS             346..1041
                     /locus_tag="ACG8ZV_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998063.1"
                     /translation="MNKVIYQLTTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSNNYLDVYKRRPDTLKKGAELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEELNSKDATVDDYYLVFTKFLTCGTE
                     SIVLMGMDYELAVPEVFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNELDRK
                     RMPYQRFERKKGQ"
     gene            1206..1406
                     /locus_tag="ACG8ZV_002816"
     CDS             1206..1406
                     /locus_tag="ACG8ZV_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998064.1"
                     /translation="MNKIIPLLLVLFVGEILMRLSAAVHLNLAVFLVILMFCLIFWRF
                     VLALVSLLFKMIAAIFFIGLFR"
     gene            1422..1601
                     /locus_tag="ACG8ZV_002817"
                     /pseudo
     CDS             1422..1601
                     /locus_tag="ACG8ZV_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1663..1847
                     /locus_tag="ACG8ZV_002818"
                     /pseudo
     CDS             1663..1847
                     /locus_tag="ACG8ZV_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003027804.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
     gene            1881..2312
                     /locus_tag="ACG8ZV_002819"
     CDS             1881..2312
                     /locus_tag="ACG8ZV_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HFS4998065.1"
                     /translation="MLSEPLAKTYPAIFSPEEGGGYFIEFPDVQGAYTGINEDDISYG
                     IAMAQEVLGMVLADYIEHEDLLPEPTPINKISVEDDSFTTLIRVDVAKYLKDTELVKK
                     TLTIPQWADKLGKRAGINFSVLLTESIADKADNILRSGRNN"
BASE COUNT          878 a          387 c          513 g          691 t
ORIGIN      
        1 atgagacacg tgttccaaaa aaacattata aggaaagatt gtcggtagct gtggaagaaa
       61 tgattgaatc gggtgtcgaa atgaatctca ttgcgaccta ctatcgaacg cttgaagaac
      121 tgaaaaagca aaatggacaa tggtttttcc aagccttact atgcttggaa gcaggcgtca
      181 agccaaacac tatcaaacct tctgaatacc aagctttaga actaacgtat gggaaatttg
      241 tcgaaacgaa aaaagccaag actgtttcaa gtgaatggtt ggactactta gaaaatgtca
      301 acaagtatgg cgcatgttac atcatgaaaa aggaggacaa cgaaaatgaa taaggtgatt
      361 tatcaactaa caacggaaga tgtgtcacac tttttaacaa acaaagaaca tttgaatgaa
      421 gtaatcagac ggattcaaaa agactttagt tgtatggaag aaatgaagta ctttattcaa
      481 agagtcgaag aacaattgta tttggaaagt gaaacgagtc aaacgaaggt tacagtcagc
      541 aataattatt tagacgtgta taaacgtcgt cctgacacat taaaaaaagg agcggagctt
      601 ctacgactag aaacagaaaa atatatcatg aatgtttacc tagaaaggag tgaactggtc
      661 gaaaactttg tcagctacac gatttgcagg aaacactatt actcagaatc agaatattat
      721 tcaatttttg agagcatgga attaatggaa gagctaaaca gcaaagatgc gacggtagac
      781 gattattacc ttgtatttac taaatttttg acgtgtggga cggaatctat cgtgttaatg
      841 ggaatggatt atgaactcgc tgtacccgaa gtatttttga gggaatatgt agaagaagta
      901 gataacccag gcgacgactg gtacacgact ttaactgatt ttttagatac ctacacttac
      961 gacgatacag aagaaatcca aaatgaactt gaccgtaaac gaatgccata tcaacgattt
     1021 gaaaggaaaa aaggtcaata accatttata ccgaaaagtg agaatgtgtg aaataaaaac
     1081 aaaaaacctt gaaattaagg gaatggttct tatttcgcac caatcgctcc aaccgccccc
     1141 gccgcttagg tggtgcgaaa taagcgagca aagcccgaaa acctaagaga aagaaggaga
     1201 tttatatgaa caaaattatt cccttattat tagtcctatt tgttggagaa atacttatgc
     1261 gacttagtgc agctgtacat ttaaacctcg cagtattttt ggtaatacta atgttttgtt
     1321 tgatcttttg gcgatttgta ttagccctcg taagtctact attcaagatg attgcagcca
     1381 tatttttcat aggattattt cgatgaaagg agagagtacc aatgccaatt gcaataggaa
     1441 ataaacggtt acccgtgacg ttggatgaaa agagacaaaa agaattgcag taaccaaagc
     1501 agaagtacgg caaaagtgaa tccaggatta tgtgtattgc gttagattta ttgattgcgc
     1561 aagaaaaagc aggatttgac ataccagcac tcaaaaagtg atcgcacttt gcgcacgtgt
     1621 taatacgtgt tataattatt ttgtaaggag gtatagtgca caatgccact tacgggaaaa
     1681 gaaatgctta agttattgaa aaaaatggct gggttgagcg aaggcaagag ggatttcatc
     1741 atcatcttta taaggatggt gttagaatca ctgttcctgt tcatgccaat caagatcttg
     1801 gccgaggact tgagcgaaaa attttaaagg atgcgggatt gaaataatct cgcattcgat
     1861 taaagaaagg attgactgaa atgttaagtg agcctttagc aaaaacctat cctgctattt
     1921 ttagcccaga agaaggtggt gggtacttta ttgaatttcc tgatgttcaa ggtgcttaca
     1981 caggaattaa cgaagacgat atatcttatg gaattgctat ggcacaagag gtgttaggta
     2041 tggttttagc agattatatt gagcatgaag atctacttcc agaaccaaca ccaatcaata
     2101 agatttctgt tgaagatgat tcttttacta ctttaattcg tgtagatgtt gccaaatatt
     2161 tgaaagacac agaacttgtc aaaaaaacct taacaattcc tcaatgggcg gataagctag
     2221 gcaaaagggc tggcataaat ttttcagtcc ttctaacaga atcaattgca gataaagcag
     2281 ataacattct tcgttctgga agaaataatt agaactcaaa agggtcagaa acttaaaaat
     2341 ctttggcttc tttttttact acaaagatgg cttctttaaa ttatttgcct gattgattta
     2401 aaaaaattgc gcaaagacta cgagctaatt aagttgctcg tggtcttttt ttatgaaaac
     2461 tttttagat
//
LOCUS       DAZULR010000127         2453 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.135, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000127 DAZULR010000000
VERSION     DAZULR010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2453)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2453)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2453
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.135"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            71..1027
                     /locus_tag="ACG8ZV_002820"
                     /pseudo
     CDS             71..1027
                     /locus_tag="ACG8ZV_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1182..2261
                     /locus_tag="ACG8ZV_002821"
     CDS             1182..2261
                     /locus_tag="ACG8ZV_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006908283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFS4998066.1"
                     /translation="MTQNHDNTVSRKGKHLTYSERCQIAILKKENYSNRQVADVLGCV
                     PQTINNEIKRGTVTQLNRQNQNGKVYDYYHDVYDADAGQAAYEKNRLNCGRRPLWADT
                     DAFIEWADDMMLLEKWSPDVVVGFARKHELFDPAIIPGTTTLYQWIDRGIMKTKNMDL
                     LEKLSRKPKSSRHGNRPNKRVLGKSIEERPEAVGTRKTFGHWEVDTVVGNKTKSDAVL
                     LTLVERQTRFEVILKLAGKDAESVNQAVRQLRERAGAYFGQLFKTVTSDNGSEFAGLH
                     DALQDVANIYFSHPYASWERGTSENQHKLIRRFIPKGSPIGNVSENQILRIQRWMNDY
                     PRKILGYATPHDTFVQAFRQERLTA"
BASE COUNT          760 a          521 c          554 g          618 t
ORIGIN      
        1 gttgacaggg aatcctaaaa acattcggct ttttttatat aatcttttta actcaacaga
       61 gataagtttt gtggaattgt atacgctacc tataattata aaaacagaaa aaatgttaaa
      121 agatttaaaa cagtattatc ctctgtctgc ttatgaaaaa aagaaattat tccacttttt
      181 agcaatcaac ctgttggctg aacaagctga ttctttagat attgctagca atcagtcgct
      241 atttttttcg gatataggat tttaccactt aaaaggagta ttaggagaaa aatccgttat
      301 ttttatcaat aagacactct cttggcttta tcttcatgat aaattggatc aaaaatactt
      361 gagaaaaaat gaagatgaaa caatcgaatg gttgaatgaa tgattcattg aaagttttga
      421 aaatcagttt aatctgttgc gagaagagac gagccaattg atccgaagag agttaaccaa
      481 aatacatttt aaacttttgc attacactat taataaagct gatgaatttc cacttgatgt
      541 ttcttttttt agagaaaact atccagcatt ttattgctat ttgatagagt atataaatga
      601 tctaacgtca aaacgcaaag agttgcttca agataaattt tttctttttt tcagttattt
      661 attattattg atcaatcaca tacccattca actgatttct gaaccagtaa agatcatcat
      721 cgatttttct tatggtgctg cctataatca atttatcaag aaaaatttaa gcttgtacat
      781 taatctgaac acggaagtga tagaggcagg aaagcctgag ttcccggatg ttataatcac
      841 gaataggaat aatctatatg aagaaagtgc atctcaagta gtggtttggc tcgatccgcc
      901 aagagcagta gactggggga atcttacaaa gattttgttg actatccaag aagagaaata
      961 caaagacagc aaaattgaca agcaaataga cgattttcct gaagaaatca tcgacaggat
     1021 cgaatagtga acttctttta gaaagtccga ctgctttttc taaaaatatt atttgggcgg
     1081 attttataat taacttagcc atttggaaat aaaaaaacgc cacgtgaatt ccatgttata
     1141 ttgaagttac cacaactctc aatagacaag gatgaattca catgacgcaa aaccatgata
     1201 acacagtttc acgcaaggga aaacacctaa cctactcaga acgttgccaa atcgccatcc
     1261 tgaaaaagga aaactattcc aaccgtcagg ttgcggatgt cctgggctgc gtgccgcaga
     1321 ccataaacaa cgaaatcaaa cgcgggaccg ttactcagct taaccgccag aatcagaacg
     1381 ggaaggtcta cgactattat catgacgtct acgacgccga tgccgggcag gcggcctacg
     1441 agaagaaccg cttgaactgc ggcagacggc ccttatgggc cgacacggac gccttcattg
     1501 aatgggcgga cgacatgatg ctgttggaaa aatggtcccc ggacgtggtg gtgggctttg
     1561 ccagaaaaca cgaattgttc gacccggcca ttatccctgg gaccaccacc ctctatcagt
     1621 ggatcgaccg tggcatcatg aaaacgaaga atatggacct gctagaaaaa ctgtcccgca
     1681 aaccgaaatc gtcccgtcat ggcaaccgcc cgaataaacg ggtgctaggg aaatccattg
     1741 aagagcgccc ggaggcggtt ggtacccgga aaaccttcgg ccattgggaa gtcgacacgg
     1801 tcgtaggaaa caagaccaag tcggatgccg tgctgctgac gttggtggaa cggcagacac
     1861 gcttcgaggt cattctgaag ctggccggga aggatgccga atcggtcaac caagcggtcc
     1921 gacagctgag agaacgggct ggtgcgtact tcggccagct gttcaagacg gttacctcgg
     1981 acaacggctc ggagttcgcg ggactgcacg atgccttgca ggatgtggca aacatctact
     2041 tcagccaccc ctatgcttcc tgggagcgcg ggacgagcga aaaccaacac aagctgattc
     2101 gccgtttcat ccccaagggc agcccaatcg gcaacgtgag cgaaaaccaa atcttgcgga
     2161 ttcagcgttg gatgaacgat tacccgcgaa agattttggg ctatgcaacg ccgcatgaca
     2221 cgttcgtcca ggcatttagg caggaacggt tgacggcttg acacgtgggc ccttgacaac
     2281 gagcctccct cggcatggct tgtgtctgga aagctggccg gggccagcca gtcgggagac
     2341 taccatgcct cagctcattg tcaagggccc actcgattag aaaaattaga cggttggtgg
     2401 taacgagcaa ccgggtcacc atgggtggct aacttaaact tgaaatttac gaa
//
LOCUS       DAZULR010000128         2406 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.136, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000128 DAZULR010000000
VERSION     DAZULR010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2406
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.136"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..103)
                     /locus_tag="ACG8ZV_002822"
     CDS             complement(<1..103)
                     /locus_tag="ACG8ZV_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HFS4998067.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQEL"
     gene            complement(135..458)
                     /locus_tag="ACG8ZV_002823"
     CDS             complement(135..458)
                     /locus_tag="ACG8ZV_002823"
                     /inference="COORDINATES: protein motif:HMM:NF015824.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbU family protein"
                     /protein_id="HFS4998068.1"
                     /translation="MDSFQRLSLVNQFELLAKFEDQNRSYYERKIEILREGYEYHYDD
                     EIWSDLSEPFPKEDSRFVLDVLNMYRDINFSKSKLNLDENQITNSYYTHFGSVAKFSK
                     KSILV"
     gene            920..2302
                     /locus_tag="ACG8ZV_002824"
                     /pseudo
     CDS             920..2302
                     /locus_tag="ACG8ZV_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010726506.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          875 a          412 c          400 g          719 t
ORIGIN      
        1 acaattcctg aacttcacga tagcttagat tgtaacgcag gtagtaacca acagcgacaa
       61 taatgacgtc ttttttgaat tgtttgcctt taaaatgatt cattactctg tcctctctgt
      121 cttttttctc aattttacac taaaatagat tttttggaaa actttgcaac agaaccgaaa
      181 tgagtatagt atgaattagt aatttggttt tcatctaagt ttagctttga tttactaaaa
      241 ttgatatctc gatacatgtt caatacatct aatacaaatc gagaatcttc tttcggaaat
      301 ggctcagaaa gatcactcca aatttcatca tcataatgat actcgtaacc ttctctcaat
      361 atttcgattt ttctttcata ataagatctg ttttggtcct caaatttagc caataactca
      421 aattgattta ctagtgacaa tctctgaaaa ctgtccatta aatgtttctt cctatcttgt
      481 tcattaacaa aaaattataa gcccttacaa cgaatattat atattaaatt taattgtagg
      541 tgaacacgaa ttttataaat atttatggtg ttaatgacaa atgatatccg actcctcttc
      601 atacgttctg gactatttgc taatagatta aaatttcagc atctatttct gaccataaat
      661 aaatgagctg ccgaaaagct gccaaatcag acttgaaaat aaaggatcaa aaacttttaa
      721 gtttctgacc ccgtaactca cacttcaaaa tcttacttaa aaaggagtct gaaagaaaaa
      781 aagagtattc aaaatttttt tctaactagc tacatcacat ctatgcattg acactcaaag
      841 aaccagaata agtcatcaga aagcaagggg gtgcggacat aatcctggac gaaaaaataa
      901 acttaggagg aatgtccgtg tgttttccca caaagagcgt gtaagggcaa ttcagttatt
      961 tttaaaatac gattgctctt atgctgcaac cattcgagaa ttagggtatc cgtcgattgg
     1021 tgcactacgg aaatggtata aagagtattt ggaatccgga gagctccatc aggagcaccg
     1081 aaaaaaatca aagtattctg aagaacaaaa acgaatagcg gtgaatcatt attttgaata
     1141 tggtcaatgt tatgcacgaa ccattcgcat gcttggttat cctaatagag agtccttgcg
     1201 gcagcggtgt gaagaacttg caccaggagc tagaaaactc cgaaaaagtg cggtaaagtt
     1261 aacacaagat caaaaagaag ctgtgttgaa aaaattctat aaaccgcaaa ctaataggaa
     1321 aaatttagcc gaatctggag gaattagtag agttactcta tatcaatgga aaaacacggt
     1381 tcttggaaag gattttccat tgtgtatgac tttaaaaaat caggaaaaac aaaaagagct
     1441 acttttaaag gaagtagaag acttacaaaa acaagtacac caattacagc tcgaaaaagc
     1501 attactcgaa ggagcggctg aactgctaaa aaaagaaaaa ggcgtcaatc ttctttgtct
     1561 atcaaatcaa gaaaaaacga tattgattga tgccttacga aatcagttca ccttgaaaga
     1621 gcttcttcaa cagctccagt ttcctaaaag cagctatttt tatcaaaaac aagcacttga
     1681 gaaaccagat aagtattaca aagaacgtca aattaattat cacgattttc aatcataact
     1741 tctgtgcgta tggttaccgt agaattcacc aagctttaaa aaatatgggt aaaaagcttt
     1801 ctgaaaaagt tgtacgtaga ttgatgactg aggaaaatct atttgttaaa ttttctagac
     1861 gaaaaaagta ttcttcgtat gctggggaaa tttctcctgc acaccccaat ttattaaatc
     1921 ggaattttaa agcaaagaag ccaaatgaaa aatggttaac agatattact gaatttagaa
     1981 ttctcgcagg gaaaatctac ttatcaccac ttgtcgattg ttacgatggt gctattgtta
     2041 gttggactat tggaacaaag ccaacttgct tcactctatg tctaaaaaga gttattcacc
     2101 agataattca gcgtgcgaag gtttctttgg acgattaaaa aacgagatgt tttatcaacg
     2161 tgactggaag aatacaacaa tcaatcagtt tataaacaaa ttggatgatt atattcattg
     2221 gtataataat caacgaatta agttatcttt aggaaggcta agccctcttc aatatcggaa
     2281 gaagcaaaga tatatttgtt aaaaaggtcc aaaaaaaata tccgcacccc cttttttttg
     2341 taaaaaacta ttgcacaata caagtagcct acggctatcg aaatttccat aactttcgag
     2401 caagaa
//
LOCUS       DAZULR010000129         2395 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.137, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000129 DAZULR010000000
VERSION     DAZULR010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2395
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.137"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            316..570
                     /locus_tag="ACG8ZV_002825"
     CDS             316..570
                     /locus_tag="ACG8ZV_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFS4998069.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            571..888
                     /locus_tag="ACG8ZV_002826"
     CDS             571..888
                     /locus_tag="ACG8ZV_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFS4998070.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            1447..2382
                     /locus_tag="ACG8ZV_002827"
     CDS             1447..2382
                     /locus_tag="ACG8ZV_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998071.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNMNITSNKTSRVLLALMG
                     YGILYRDDQNGQILINRAGRSLLMKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRF
                     EVLKIQKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTD
                     VVMITDIYVEDEDIIKYMKPVIKLVNKNKGTRGAS"
BASE COUNT          861 a          339 c          453 g          742 t
ORIGIN      
        1 acaaaataaa aaggcaatac gccttagttg tcggtcttcg agttaccaac ggtaaccctc
       61 ataccgaacg gcattcatca cccacctata gaggatgggc gacttctgcc taattctgtt
      121 aaatggatgt taacggaagt gtatggtgag tagttcactc gtattttgat atcgtttgta
      181 tatgttttca gcgttctaag tggcttattt tgtccaataa taatatggag tggaatccct
      241 taagaaacac cgttggcaat tgttgttata acatgttata atttattcat caaaaactaa
      301 aaggagtgtg ataacatggg aaaagaacta aaggttagaa agatcggcaa tagcgtggga
      361 gtgatccttc caagctctct tggattaaaa agcggagaca ttatccaagc caaacaagaa
      421 ggcaacttat tcatattaga tactactcaa atagcaaaag aacacgatcg caaattgatt
      481 gaagaaagtt tccaagactt tgagaaaggt ttaacagttt cagaaattga aatggtaaaa
      541 gctttcggaa aatacggctg gagtgaatag atgaaagagt acacgctagt ttattctaaa
      601 agttttcaga ccagccttga aacgataata gaagaatggg aaaatgagct tgctctttct
      661 ccagccagca taaaaagatt tgtaggtgcg atccagaagg ctttagaact aaccaaaaat
      721 tttccaacta tgcatgagga agtttccgaa atctatggaa tggatatccc aacatatcgg
      781 atcgtgatcg gcaaaagcta tgccttattt tatcggatcg accatgaaaa aaaagagata
      841 cttgtaggac gtattttcca atctaaacaa atgaaactag gcttttaaca ataattagga
      901 aaaagtcgct catcctctac aggtgggtga ttaatgccgc tcgatatggt tgttaaccgt
      961 cggttactcg aagattgata tataagactt agtacctttt tattttgctc catgttatgg
     1021 ccgaaggtct aaagatacaa tcattagtct agagaaaaat taagaaccgt aggaactacg
     1081 gggatcgctt ggtgaataag agacactgct attagtgaaa aaataagata tcaagtacgc
     1141 tctattccca aaaatttcgt gactttactc atgagaggtt caagtagtat atttttaatc
     1201 aaaattgacg taacttttaa taaatactac ctaaataagg tagtatttat ttttgtgttt
     1261 taaaagagga agtccaatat atctatggga aacttcttaa atattatgtt ggtacatgaa
     1321 aatatacatc cctgctagac tatttacaac attttacttt gtacgtattc ttgttttaaa
     1381 aggaatggga taaaatatag gtacaataac tatttgatgc taaatataat taatggagga
     1441 gagatagtga acatacttaa tgaaaaaaga tatgtatggt ttgctggtaa aaaatatatt
     1501 actactttca aaagattatc cgagttaatg cagcagactg ttaaaagtgc tatgcctgaa
     1561 ggatacaagt ttaattttgt tcaatcttca gtatctactg aaagtatcta tttttcaatt
     1621 ctttctgaga gtaggctttt tcattttaga ataagttctc atgtaaagaa aactgatgtt
     1681 gatatatata cgttccgtac aaataattat aaaaatttaa atgatttgag tagaagtatc
     1741 agtgaatatc tcaaggggaa tagctatctc aagattcgat tttcacatat attaatttta
     1801 ctaccatatt tgaatgagaa tttcacccta attcaagtag ataagtcttt cattgcctca
     1861 ggtaatcaag gaaatatgaa tattacaagt aacaaaacgt cacgtgtgct attggcgttg
     1921 atgggttacg gaattcttta tagagatgac caaaatggcc agattctaat aaatcgggct
     1981 gggcgttcat tattaatgaa atatagaaaa tttataccgg aagattttca aaacttacag
     2041 ttagaaaaca tgcgtttaga agatttattt agattagcag aagatgataa gtatagattt
     2101 gaagttttga aaattcaaaa gaatgaacta ttgaataagt tatatcctga gaatgcgata
     2161 aaagcacatt ttggtgatgc taatcatatg tatagttggt tcattcctaa aagatttaga
     2221 gggaaaatca atgctggaga tcaagtgaaa gtactcaatc gaaatagtac agatgtcgta
     2281 atgataacag atatctatgt agaagatgaa gatataatca aatatatgaa gcctgtgata
     2341 aaacttgtta ataaaaataa aggaacccgt ggtgctagtt aattttttcc tagag
//
LOCUS       DAZULR010000130         2330 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.138, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000130 DAZULR010000000
VERSION     DAZULR010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2330
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.138"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..331)
                     /locus_tag="ACG8ZV_002828"
     CDS             complement(<1..331)
                     /locus_tag="ACG8ZV_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998072.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYK"
     gene            complement(333..1760)
                     /locus_tag="ACG8ZV_002829"
     CDS             complement(333..1760)
                     /locus_tag="ACG8ZV_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HFS4998073.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGAMISFILTIIINRENFLIPSIYNFGYLL
                     ITLIVIFPADFSQSEEEKKKKMVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPG
                     LLARQGFIEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQI
                     FYITLSSSRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFS
                     FGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIW
                     KAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLV
                     SSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFN
                     KRDVISIVFWYYLGSISYLYLKKEN"
     gene            complement(1753..>2330)
                     /locus_tag="ACG8ZV_002830"
     CDS             complement(1753..>2330)
                     /locus_tag="ACG8ZV_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="beta-1,6-N-acetylglucosaminyltransferase"
                     /protein_id="HFS4998074.1"
                     /translation="KEFYYKHIDVYQKHDYPRINRNNTTAFKIFRAIINRCLRMIKLP
                     PKIRHHKFDLYHGSQWWALSKECLTELIQMYEQNQQDYLNFKIGMFAPDEKFFHTLFF
                     NSSFKNKNVIGGPDLPLELKNIEETTLQTSKLANIHIIDPSMNKWFDERDIDQIKESE
                     KLFVRKVKSDYSDKLLNRIDKEILKVGNIDE"
BASE COUNT          877 a          370 c          276 g          807 t
ORIGIN      
        1 ttttgtaaac attggagaaa agtatttttg tgaaataatt ttccccctgt ataaaaattt
       61 catcataaac ggataaatca tccgagaaaa attgattatg gttagttaac aagttaattt
      121 tacgtttaaa ggaagaaccg attttccggt gattcacaaa aacaacatca ttaaatagcc
      181 ctaattcttt tatacgctca ctatatcttc tagcgttttc aaattcagaa taaataaata
      241 aatctccttt tgattctcgg taaaaatttt gataaacatt taatatatta atcaaatgta
      301 aaggagtcca agcaatgaaa gctgtcttca tattaattct ccttttttaa atacaagtaa
      361 gaaatgcttc ccaaataata ccagaaaaca attgaaatga catcgcgctt attgaaaagt
      421 acatgagcct ccaccatttc atctataaaa atagatagta taaaaattaa aacaatacca
      481 agaaacgcat aattcacttt acttctaaaa aatgttttga gtaaactaaa gatatttaac
      541 acatagaaag catagataca tataaaagca attataccac ttgatacaag tacttgaaga
      601 aatccattat gcatgtttcc atgtgctctt tttagttcat tcacatctgt agtatcaaga
      661 tctacttttt tcaaaaattt tgcatcgcta ttcccataga aatcggtctc tccataacca
      721 aataacaaag ttggtcttat aactttaagc gcagctttcc aaatcgtaaa acgaccagct
      781 gaaatttcgg agttatcact agaatgctgt aatattactt ctttttctgg aagtggagtt
      841 ttatctgatt catttgactc tataacttct acttttctat caatcgatac aggaattgtt
      901 gctaaaaaat ccttagcata attagtacca aaagaaaaat ataccaatag aactaataat
      961 atgcttacca tccatttgat ttttacaggt agtacttctc taatgctctt tctaaatttt
     1021 gaattggcaa acaacaaaag aaataatact aaaaaagaac aaattactac ctgggcacct
     1081 ctagacgaag aaagtgtaat ataaaatatt tgtacgataa aattcatcat ataaaaaaca
     1141 cgaatcgttt ttgttatttt tgaaattaat acactaatta aacttaaaat aatagaagta
     1201 tatccaaaca tagctccaac atttggactt gtatagacac caaataaccg atgttcaata
     1261 aaaccttgtc ttgcaagtaa tcctggcgtt cctgttggga catgataaga aatcaaaaaa
     1321 ataaattgat agatagatat tagcgcagct aaaaaaatta tgataatgaa aacattatta
     1381 aaatacacca tttttttctt tttttcctct tcactttgtg aaaagtctgc aggaaaaatt
     1441 actatcaaag taatcagcaa atatccaaaa ttataaatag atggaattaa aaaattttct
     1501 ctgttaatga ttatagttaa gataaaacta atcattgctc caatcagtag ccaagaaaaa
     1561 cgcattttaa aaaaattttt ctttataaaa acctcataca aaactataat tccaccccaa
     1621 gcaaaagcta ttttcatcgg gatattagtt acattaaaag tactaggcat aaaataaagc
     1681 agacaaatga ttaaatttat tactcgaaac gcatctcgac ttaataaact cttctctaaa
     1741 acaggtacta ttctattcat ctatatttcc aactttcaaa atttctttat caattctatt
     1801 taatagttta tcagagtaat ccgatttaac ttttcttaca aataattttt cactttcttt
     1861 tatttgatct atatcccttt catcaaacca tttgttcatg gaaggatcaa taatatgaat
     1921 atttgctaat ttcgaagttt gtaaagtagt ttcttcaata tttttcaatt caagtggtaa
     1981 atctggtcct ccaataacat ttttattttt gaacgaggaa ttaaaaaaaa gtgtatgaaa
     2041 aaatttttca tctggggcaa acatacctat tttaaaattc aggtagtctt gttgattttg
     2101 ttcatacatt tgtattaatt ctgttaggca ttctttcgac aaagcccacc attgagaacc
     2161 atgatacaaa tcaaatttat ggtgtctaat ttttggggga agtttaatca tcctcagaca
     2221 acgattaatt atagctctaa aaattttaaa tgcagttgtg ttattcctat taattctagg
     2281 ataatcatgt ttttgatata catctatatg tttataataa aattctttat
//
LOCUS       DAZULR010000131         2248 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.140, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000131 DAZULR010000000
VERSION     DAZULR010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2248)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2248)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2248
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.140"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            150..1190
                     /locus_tag="ACG8ZV_002831"
     CDS             150..1190
                     /locus_tag="ACG8ZV_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HFS4998075.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
     gene            2014..>2248
                     /locus_tag="ACG8ZV_002832"
     CDS             2014..>2248
                     /locus_tag="ACG8ZV_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HFS4998076.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPT"
BASE COUNT          865 a          317 c          372 g          694 t
ORIGIN      
        1 agtacataat tcattttatt tctgatttta ggtagtattt aattaaaaaa cagttttaat
       61 gcgtttgcat tttttattta tctttgctat tttcgaaaag agtaggtaat tttacataaa
      121 taaaacaacg tgaaagtaga ggatctacaa tgactgattt taaatttttt aaggcggata
      181 gagtttacaa cgaattattt tatcaatttc caaaagtctt tattgtttct gacgaataca
      241 aaaaaatgaa agattcaact aagattgcct atatgctttt aaaagcaaga ttagagatcg
      301 caatcagcaa acggcaaatc gatgaagaag gtaatgttta ttttacttat acgacaaatg
      361 aactatgtag agtattaaac tgccaaaaac aaaaagcgat agcaatcaaa aaagagttgg
      421 aatcctttgg tttattatta caaaagcaga tgggatttaa caaacagtta gggaaaaata
      481 atcctaatag actatatcta gcagaattaa aagtctcaga aaatgatatc tacttactcg
      541 aaaaatttga tagagagaat agggaaaacg ttgataaatc agagggtatg aaaatcatac
      601 ccaccctcga cgaaaaatca gacgctgaat cccttggggc tcaagagggt atgaaaatca
      661 taccgtgcca aaacgttgat aaatcagagg gtatgaaaat cataccagaa cttaataata
      721 atatattaga cactaataga cacaatatag acactgaaaa agaccgccta caagatcaat
      781 tgttgttaga caattttgag acaattatga caaacgacag cattgctacg tttgtccctg
      841 aacgagtatt aaatttgata aaaacatttt cttcaagtta cagtgaagct caaaaaaccg
      901 tccagactat tcataatgca aagaaaaaag ctgaaataga aagtgatatt tcgatagttt
      961 ttgaagaact cgatagttat tatgtcaatg cagaacaaga attatacacg acactgttaa
     1021 aagcctatca aaaattaaaa accgaaaaag tcgaaaatat ccagaacctg atttttgtct
     1081 atgtaaaaaa ttggtttatc gaaaaaccaa tagctgctaa agtatcaagt gaaaaacgtt
     1141 tgaattatgc aagctcccca agcactatta cgaaagactg gttagagtga aactttactg
     1201 acaaagtgat tgttgcttca tggagtaaca ttaaaattaa aaatttttta ttattctaat
     1261 tatattacga atattacaaa ataatagcta ttttaataga atttataagt taaaatatta
     1321 tgataaaaat cacaaacgta gccttttacg tcataagtgt taaaagaaat aattaatttc
     1381 aaatatagaa aagggaacgt atgtttgcat actccttttt tttgagttat aataatacgc
     1441 gaagagagat aatttcatta tttaaacaag ctaaaaatct tgatattact tcttttcagg
     1501 caatacgaat attattcgct tacatttttt gtataaattt aattgtctgc tatgcttgtg
     1561 atgaattgat tttcgttttg cacttttgga tgataaattt ggacaattga aaatacaaaa
     1621 aaaagaaagg cggtatgaac tcggaaggct ggtaaccttc gtcagcgttc atacacggca
     1681 ttaagatttg gcccttaatg cgttaacctt tcagtgttac ggtattaccc gcaatggatt
     1741 tagtataaca gatattcaaa agtgatacca ctttttttgg ctgtgttaag gttaaaaata
     1801 cgtgatatta cgatgaatct atgcctaagc ataatgttat aaaaatgtcc gtgtggctct
     1861 ttgccgtatg acgaacgctg aaattagagg gaacgcatgt ttggatgcgt tccctctttt
     1921 ttgtttgtca tgaacgaaaa tcaattctct atttttgaaa aataacaaga aaaacttgtt
     1981 aaaaatattt aaagaaattg ggtggtttat tttatgtcat atacaggaat tttgagtctc
     2041 aaagatattt gtcactacgg taaacggtgt accgctacag agaaaatcac gaagaaacta
     2101 tcaactggcc aaagtaaaac cgttgtgcag tgtaagaaat atataatcca gaaagacaaa
     2161 gtctcagagg aaatgattta ttacattggg aaacaaaagc aaataatttt aaaagatcct
     2221 atccccttaa aagagctata tccaacaa
//
LOCUS       DAZULR010000132         2226 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.141, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000132 DAZULR010000000
VERSION     DAZULR010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2226
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.141"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            5..397
                     /locus_tag="ACG8ZV_002833"
     CDS             5..397
                     /locus_tag="ACG8ZV_002833"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4998077.1"
                     /translation="MKLLFIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDEIVYVYDYEKGDK"
     gene            398..1837
                     /locus_tag="ACG8ZV_002834"
     CDS             398..1837
                     /locus_tag="ACG8ZV_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase
                     APH(2'')-Ia"
                     /protein_id="HFS4998078.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYDGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPI
                     ETIVYGIKNIKQEFIENGRKEIYKRTYKD"
     gene            complement(1967..>2226)
                     /locus_tag="ACG8ZV_002835"
     CDS             complement(1967..>2226)
                     /locus_tag="ACG8ZV_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFS4998079.1"
                     /translation="KYSKACASLDDGFEDAFQYTVQGNSHNRLKSTNLIERLNQEVRR
                     REKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
BASE COUNT          888 a          195 c          382 g          761 t
ORIGIN      
        1 cctattgaaa ctattgttta ttgatgataa tatggttttt gatattgata atttaaaagg
       61 atttcttaat gataccagtt catttgggtt tatagctaaa gaaaataata aaattatagg
      121 atttgcatat tgctatacac ttttaagacc tgatggaaaa acaatgtttt atttacactc
      181 aataggaatg ttacctaact atcaagacaa aggttatggt tcaaaattat tatcttttat
      241 taaggaatat tctaaagaga ttggttgttc tgaaatgttt ttaataactg ataaaggtaa
      301 tcctagagct tgccatgtat atgaaaaatt aggtggtaaa aatgattata aagatgaaat
      361 agtatatgta tatgattatg aaaaaggtga taaataaatg aatatagttg aaaatgaaat
      421 atgtataaga actttaatag atgatgattt tcctttgatg ttaaaatggt taactgatga
      481 aagagtatta gaattttatg atggtagaga taaaaaatat acattagaat cattaaaaaa
      541 acattataca gagccttggg aagatgaagt ttttagagta attattgaat ataacaatgt
      601 tcctattgga tatggacaaa tatataaaat gtatgatgag ttatatactg attatcatta
      661 tccaaaaact gatgagatag tctatggtat ggatcaattt ataggagagc caaattattg
      721 gagtaaagga attggtacaa gatatattaa attgattttt gaatttttga aaaaagaaag
      781 aaatgctaat gcagttattt tagaccctca taaaaataat ccaagagcaa taagggcata
      841 ccaaaaatct ggttttagaa ttattgaaga tttgccagaa catgaattac acgagggcaa
      901 aaaagaagat tgttatttaa tggaatatag atatgatgat aatgccacaa atgttaaggc
      961 aatgaaatat ttaattgagc attactttga taatttcaaa gtagatagta ttgaaataat
     1021 cggtagtggt tatgatagtg tggcatattt agttaataat gaatacattt ttaaaacaaa
     1081 atttagtact aataagaaaa aaggttatgc aaaagaaaaa gcaatatata attttttaaa
     1141 tacaaattta gaaactaatg taaaaattcc taatattgaa tattcgtata ttagtgatga
     1201 attatctata ctaggttata aagaaattaa aggaactttt ttaacaccag aaatttattc
     1261 tactatgtca gaagaagaac aaaatttgtt aaaacgagat attgccagtt ttttaagaca
     1321 aatgcacggt ttagattata cagatattag tgaatgtact attgataata aacaaaatgt
     1381 attagaagag tatatattgt tgcgtgaaac tatttataat gatttaactg atatagaaaa
     1441 agattatata gaaagtttta tggaaagact aaatgcaaca acagtttttg agggtaaaaa
     1501 gtgtttatgc cataatgatt ttagttgtaa tcatctattg ttagatggca ataatagatt
     1561 aactggaata attgattttg gagattctgg aattatagat gaatattgtg attttatata
     1621 cttacttgaa gatagtgaag aagaaatagg aacaaatttt ggagaagata tattaagaat
     1681 gtatggaaat atagatattg agaaagcaaa agaatatcaa gatatagttg aagaatatta
     1741 tcctattgaa actattgttt atggaattaa aaatattaaa caggaattta tcgaaaatgg
     1801 tagaaaagaa atttataaaa ggacttataa agattgatta tataatatat gaaaagctat
     1861 tataaaagac attagtatta aatagtttaa aaaaatgaaa aataataaag gaagtgagtc
     1921 aagtccagac tcctgtgtaa aatgctatac aatgttttta ccatttctac ttatcaaaat
     1981 tgatgtattt tcttgaagaa taaatccatt catcatgtag gtccataaga acggctccaa
     2041 ttaagcgatt ggctgatgtt tgattgggga agatgcgaat aatcttttct cttctgcgta
     2101 cttcttgatt cagtcgttca attagattgg tactctttag tcgattgtgg gaatttcctt
     2161 gtacggtata ttgaaaggcg tcttcgaatc catcatccaa tgatgcgcaa gcttttgaat
     2221 attttg
//
LOCUS       DAZULR010000133         1993 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.142, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000133 DAZULR010000000
VERSION     DAZULR010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1993
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.142"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            273..839
                     /gene="amaP"
                     /locus_tag="ACG8ZV_002836"
     CDS             273..839
                     /gene="amaP"
                     /locus_tag="ACG8ZV_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HFS4998080.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            852..1040
                     /locus_tag="ACG8ZV_002837"
     CDS             852..1040
                     /locus_tag="ACG8ZV_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HFS4998081.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            1053..1610
                     /locus_tag="ACG8ZV_002838"
     CDS             1053..1610
                     /locus_tag="ACG8ZV_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFS4998082.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            1642..1884
                     /locus_tag="ACG8ZV_002839"
     CDS             1642..1884
                     /locus_tag="ACG8ZV_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFS4998083.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
BASE COUNT          724 a          308 c          406 g          555 t
ORIGIN      
        1 aataaataga atcttgtaat aataactgag cataatcttt gcaattttta atcttgaata
       61 atatccttta agtatagcca gcaatcaaaa gtaaatagag aataagtaag caattgttat
      121 ttcagtatca gactggcaat aaaacgccgt tatgatccag caatgtttgg tagcgcttta
      181 tttactgatg ctatgctaac tgttcgctat ctatactgtg attgtcggta gagttattta
      241 cagggtaaaa ataagtttat aggaggtgga aaatgaataa ggggttaaaa ataatcggtg
      301 ttatcatgag tttactgcta ctttcagtat ttctagcgat tgcgttgatc aatgcgccgt
      361 atattatgcc tgaacaattg gaacgatttc gcttctttac tttaacgaat tactacatgc
      421 aacaatatat tttctgggca gctgtagtat ttgccgttct tgctattatc atcttgctag
      481 tcgttctttt ctatccaaag tcaagaggaa ctttcgttat gaaacgggaa gatggcaaac
      541 taacaatcga caaaaaagcg atcgaagggt tggtacgttc ccatttacac gaagaagagt
      601 tcattcattc acctaaagta cggatacgtt caacgaaaaa tcgaatccat atccatgtca
      661 acggagactt gaaacgaact tcttcattag tagggaaaac aggtgtattg atgcaagata
      721 tcgaagaaga agtaactaaa gtactcggaa caaaagaaac ggtcaaagtg gcagtcacat
      781 acagcggtta tgaagaacaa gaagatacaa gagactacaa gcactctcga gtggaatagg
      841 agggccaaat aatgaaagaa ctattttcag catacaagct ccctattatc tttgggggtc
      901 ttggactact gctagctgtt ttatggttaa cgattggatt tttcaagaca ttgttgatca
      961 taatcatgac agcaattggc gcaggaatcg gtttttattt gaaacagtca ggaatagttg
     1021 atcaattttt taaatcatag gaggaaacaa agatggaaaa caaaaacatg aatacaacaa
     1081 atggatcagt tttggcaaat gaaaaaggag aaaaccgcat gatgaatggt gaattgactt
     1141 atgaagacaa agtcatccaa aaaatcatcg gttatgcatt gaaagatgta gatggtctat
     1201 tgacattaga tggcggattt ttctcaaata tggctgaaaa attagtcaac acagataacg
     1261 taacagcagg tatcaataca gaagtaggta agaaacaagt agctgtggat ctagatgtga
     1321 tcgtagaata cggtaaagac atcgaagata tttacaacca aatcaaagaa ttgatcagta
     1381 ctgaagtaaa caatatgaca catttagatg ttatcgaagt gaatgtgaat gttgcagaca
     1441 tcaaaacaca agaagaatac caaaaagatc aagaaacagt acaagacaaa gtaacagaag
     1501 cagcaaaatc cacaggacaa tttgcttcac gccaaacaga taaagcaaaa tctgctgtag
     1561 gcaaaggtgc acaaaaagtc aaagaaaata acgaaccacg tgtacaataa gaagtaagaa
     1621 gtcagttagg aggaatttaa aatgggattt atttgggcat taatcgtcgg cggtatcatt
     1681 ggagcaattg caggagcaat cacgaataaa ggatcatcaa tggggatcat cgcaaacatc
     1741 attgctggtt tagtaggttc agcaattgga caagctttac taggaacttg gggaccaaca
     1801 attgcaggaa tggctatcat tccatcattg atcggtgcaa tcattttagt attagtcgtt
     1861 tcattctttg cacgtaaatt ataagcaaat tgaagaaaaa cttatgttga aatgaagaac
     1921 aaatttgaga accgtagcga cactcgctgc ggttcttttt tatatatttt atatgaagta
     1981 ttctttattc ctt
//
LOCUS       DAZULR010000134         1933 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.143, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000134 DAZULR010000000
VERSION     DAZULR010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1933
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.143"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..435
                     /locus_tag="ACG8ZV_002840"
     CDS             <1..435
                     /locus_tag="ACG8ZV_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HFS4998084.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPVQAEQPVVQET
                     VQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQL
                     DSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(759..842)
                     /locus_tag="ACG8ZV_002841"
     tRNA            complement(759..842)
                     /locus_tag="ACG8ZV_002841"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(806..808),aa:Leu,seq:cag)
     gene            1370..1870
                     /locus_tag="ACG8ZV_002842"
     CDS             1370..1870
                     /locus_tag="ACG8ZV_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4998085.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
BASE COUNT          626 a          364 c          329 g          614 t
ORIGIN      
        1 tactcaggac aacaattaac aatcccaaca gaaggctctg cacaagcagc tgctgaacct
       61 caagcagccg ttcaagaagc accagtccaa gctgaacctg ttcaagctga acaacctgtt
      121 gtacaagaaa cggttcaaac ggaaacacaa gcagcgcctg ttgctgaaac acaacctgct
      181 cctgctgtaa cagaaactgc tgctactcca gcaagtacaa gctctgcaaa agaatggatc
      241 gcacaaaaag aatcaagcgg ttcttacaca gcaacgaacg gacgttacat cggccgttac
      301 caattagatt cttcttactt aaatggtgac tactctgctg caaaccaaga aagagtagca
      361 gaacaatatg ttacttcacg ttatggttct tgggaagcgg cgaaagcatt ctgggaagca
      421 aacggttggt actaagattc attatttgaa cgtttaaaca cattcaaaat atagtaagag
      481 gtcatgcgat ttattctttc gcatgacctc tttttgagtt taagtttagt ctttattcct
      541 taactatcgt ttgccagtat ttcttgtatc agaatctata aatctactat ttgaatcaat
      601 ctattaggtt ttaaactgtc ccaccttcac acaaattttt tttgatttat ttgaatctgg
      661 ttccgttgtt taaaattttt cctatattct tttagataat atgttatttt ctttctcatc
      721 gctccaggtg taccttctct ttataaaaaa acaaattatg cggctaagaa gactcgaact
      781 tccacgaggt caccctcact agcgcctgaa gctagcgcgt ctgccaattc cgccatagcc
      841 gcatcacatc ttttagttta ggattacatg tgttttttgt caagaacata tttttgttct
      901 ttttcatttc tgtacgccct cccttatgcc atctacacaa ataattcatc cgagcaactc
      961 catcatctat tgagggttgg tgaaaaaatc tgttttatcc atatgatcga tttcaatgtt
     1021 aaacgaacga ctctgggatt agtaactatt ttattttttt cttcatttct tttttcctct
     1081 ttttctcgat tcagctatct tctttcattt ggatattgat tatttcttct gttgattact
     1141 atccttctgg aattctagac gctgaagtaa ttcacgtttt ctttcttcta gagatcataa
     1201 gtaacgaatg aacgaacttc aaataatttt tttattgtaa ttcatatttg tattgttcga
     1261 tgattcttaa tacgatatga cacaataaat aaaaataggc atggctattt acaacaatag
     1321 tgctatagta gaaaacaaat gaataaggtt acttaaagag gtgaatacga tgaaactgat
     1381 caaactatgg gaagcagatt taaagaaagc ttatcagcta caaactagct ttggaccaaa
     1441 tgagagtgga tttatcaaca atgcttatgg ctatacattt gctgaatttt tagattatgt
     1501 aaaaaaatgc gaaaaaacgt ctttaggaat cgatcttcct gagagttacg ttcccgcaac
     1561 cgtctttatt ttagaaagtg atgaacatga gtatgtagga atttttaatt tgcgccataa
     1621 actgaacgaa acattaagaa acggcgctgg ccatattggt tacggcatct cccctaatta
     1681 tcgtaaaaaa ggatatgcca cacaaggatt agcattagta ctacaagagg caaaaaaaat
     1741 cggcattgat gaggcacttt tgtctgtaaa taaaaaaaat cttggcagtc ttaaagcaca
     1801 acaaaaaaat ggggctgcga tttatcgtga agatgagaaa gaatactata cgaaaatcaa
     1861 actgatgtaa aaaagaagga ttccaaaagg aaagggattt gaatgtcctt tatcaataga
     1921 acacatttat tta
//
LOCUS       DAZULR010000135         1889 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.144, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000135 DAZULR010000000
VERSION     DAZULR010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1889)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1889)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1889
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.144"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(62..286)
                     /locus_tag="ACG8ZV_002843"
                     /pseudo
     CDS             complement(62..286)
                     /locus_tag="ACG8ZV_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877485.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(840..926)
                     /locus_tag="ACG8ZV_002844"
                     /pseudo
     CDS             complement(840..926)
                     /locus_tag="ACG8ZV_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
BASE COUNT          658 a          266 c          251 g          714 t
ORIGIN      
        1 taggtatttt tattatatat agatttaaca tatgtcggtc ggttgattga tatagctaaa
       61 gttataactc aaccgaagcc gattcatcta cacgaataaa gttgcgagtg ttctcggcta
      121 attcataaaa attgttatgt gttccatata gcaatactgg aataacttta ttttcttgaa
      181 tctcataagc aactctatac acggtgaccg catacttaaa tccattagac caattacctg
      241 ataaacctcc agttttttgc tcttacttaa atggatcaat ggcaatttca tcacaaacct
      301 atagaggatg agtgacttct gcctaattac gttaaaaaat attgaaagta actctatgta
      361 gcaaaaaata tctagaattt catttcctca aaactgatcg atattgtatc taaaaatata
      421 tactacctaa aataggtagt atatattaaa atatgtgctt ttgttagaaa aatcaataca
      481 taaattatca tatctgtata tgtcatttag gtatttcagt tatgttataa tagttttgct
      541 gtctgctacc ccggcctaat ctggcaaggg gaggaggaga tataatgaaa tacctttttg
      601 attttgtttt tgcaatcaag ccacttgcag atgtagtgtg cagttacctc tgcaaatggc
      661 ttgattgcaa aattgccaaa aaagacagta agcctacccg ttaattctat aatatagaaa
      721 cgtaaaaaaa accccatcag cctgcacgct gatggggttt ggtgatataa tgaaatacct
      781 ctttgttact cataattata ccataattag tcacgaatgc aaccaataga aaaaactact
      841 tagaacggta gatcatcgct aataacaatg cattgtccac caaatggatt ttgtgaagca
      901 ttaaatacat tgttattaat tgtcgctgct tttaactagg cctctcccct tctattataa
      961 aagaagatat atatcatttc ttaattacct actaccttaa accaaaattt aagtactacc
     1021 taatttaagt agtacttaaa caatctaaaa aatagttatc ccaattgtta tgcttttata
     1081 atacgattat ttgtaacaaa atgaatatta tataattaaa cactaccata tttaggtagt
     1141 gtttaattat tagcaaaaca aaaaatattt attctattct cttaacttca actaagttat
     1201 gctgcacacc tttatataaa tcatatgcaa ctcattagct agacaaacta caagcatgta
     1261 gttttatctg ttaattatgt actacctaaa taaagtagtt tataattagc aagtatatat
     1321 atttaaaaat ttaagattaa tttttttatg acttgtacaa atttatctga tattctctta
     1381 ttaagaacta cctaatttgg gtagttctta ttttttacat tttaagtagt atttaattgc
     1441 aatttggtag tattttttta ttatcttatt cttagaacgg tagtacttaa tataaatata
     1501 ggtagtatct aatttaagta ttaatggtag tatctaaatt aacaggtagt atgtaactac
     1561 tttaaagtaa tttttttcag attaacacag tagtatctta ttaaataagt taattttaat
     1621 ggtagtacat aattattata tatatctgac attggtagta cttattgtat tttttagtag
     1681 tatataatct attgttttct agcctaaagc cttgtcttat aagaataata taatatatac
     1741 tactgaaata aggtagtata tattactagt aatggtagta tgttttatat gcataaggta
     1801 gttcttaatt tattttttgt tttgacactg gtagtactta attatcttta attttaaaac
     1861 taaattttat tcatacgttt ttctggtag
//
LOCUS       DAZULR010000136         1732 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.145, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000136 DAZULR010000000
VERSION     DAZULR010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1732
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.145"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(156..1297)
                     /locus_tag="ACG8ZV_002845"
     CDS             complement(join(156..1069,1069..1297))
                     /locus_tag="ACG8ZV_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFS4998086.1"
                     /translation="MAKAKKKFDEDFKKMILDLNQSGQSVEELAAQYGIATQTIYRWK
                     KLHTKNVATGMTEAEILAMKKEMARMQEENTIPKKGFNHIRSKVKMSDVFEFIQSNVH
                     DHDVKQMCTVLEAPKSSYYDWKKKKPSKRQSENKRLNRLISGIYFENKGIYGAPKIHK
                     ILVGRGETLSLKKVQILMRKLGLRSVTLKKYKPGKQAKVKSEGRKNLLNQDFTTTSIN
                     QKWVTDITYIHTLKDGWTYLSTIQDLHTKKVIGWKFGKQMTKELVIETLDNALLNQTP
                     SENLIIHSDLGSQYTSEAYEAKLNELNIRHSFSRKGCPYDNAGIESFHASLKKEEVYP
                     SKAYENFEAAYLALFQYIEGFYNRKRIHSSINYLTPNQMEELALQA"
     gene            1545..>1732
                     /locus_tag="ACG8ZV_002846"
     CDS             1545..>1732
                     /locus_tag="ACG8ZV_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998087.1"
                     /translation="MVHSTIGVVVEKSRDNLVFVTEIQTGRSFVVTDKAAKAYQSSDI
                     LTLNLTTKTFVDATEDYP"
BASE COUNT          463 a          334 c          365 g          570 t
ORIGIN      
        1 gacacgattt gtgagaattt tttcgagatt ccagcgggtg agtatctcat cgtttcgacc
       61 agcggtcaaa ccaaaaccgt ttgaccgctg atcgaagcga tgaagttgaa accctgtgga
      121 aatctcgcca aaaaaatgta agtggtagct aggaactaag cttgcaatgc caactcctcc
      181 atctgatttg gtgttaaata gttgatacta ctatggattc gcttgcgatt gtaaaatcct
      241 tcaatgtatt gaaataacgc taaataagca gcttcaaagt tttcatacgc ttttgatgga
      301 tagacttctt cttttttgag tgaggcgtga aacgattcga taccggcatt atcgtaggga
      361 cagcccttac gactgaagga gtgccgaatg ttcaattcat tcagctttgc ctcataggct
      421 tcgctagtgt actgagaacc caaatctgag tggatgatca agttctcgga gggtgtttgg
      481 tttaagagcg cattgtcaag ggtttcgata accaattctt tcgtcatctg cttgccaaac
      541 ttccaaccga tgactttctt tgtgtggagg tcttgaatag tggagaggta ggtccagcca
      601 tcttttaggg tatgaatata ggtaatatct gtcacccatt tttgattgat cgacgtagtg
      661 gtaaaatctt ggtttaacag gtttttacgt ccttcacttt taactttcgc ttgtttgcca
      721 ggcttgtact tcttgagggt gactgaacgc aagcctaatt ttctcatcag tatttgtact
      781 ttctttaagg acaaggtctc gccacggcca acaagaatct tatgaatttt aggcgcacca
      841 tagataccct tgttttcaaa gtagattcct gaaatcaagc ggtttaagcg tttgttttct
      901 gattggcgct tggaaggttt ctttttcttc cagtcatagt agctggattt cggtgcttcc
      961 aaaacggtac acatttgttt tacgtcatga tcatgaacat ttgattgaat aaattcgaag
     1021 acatcactca tttttacttt tgagcgaata tggttaaagc cttttttagg atagtgtttt
     1081 cctcctgcat gcgggccatt tcctttttca tcgctaggat ttctgcctca gtcatgccgg
     1141 ttgctacatt ctttgtatga agcttcttcc aacgataaat cgtttgtgta gcgataccat
     1201 attgcgctgc cagttcttcg accgattggc cagactggtt taaatctaag atcatcttct
     1261 taaagtcttc atcaaatttt ttcttggctt ttgccatcgt ggacacgtcc ttttcttagt
     1321 agttagattc taccaaatcg tgtccatgaa atcatcctaa catcacattg aagagtccat
     1381 ttcactcaca gagtgttagt tgttaagtga ataaaagaag taaaagagtc ctgaacgtga
     1441 ttgtccagga ctcttttttt caatgaattg ttttccgcca actcattgag tggtgcgatt
     1501 tgcgactaca ttatatcaaa agaaagagaa gggaggaagc agaaatggtt cattcaacga
     1561 ttggagttgt tgttgaaaaa agcagagaca atctcgtttt tgtgacagaa attcaaacag
     1621 gcagatcttt tgtcgtcaca gacaaagcgg caaaagctta tcaaagtagc gatattttaa
     1681 cgttaaatct gactacgaag acgttcgtcg atgcgacaga agattatcca tt
//
LOCUS       DAZULR010000137         1536 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.146, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000137 DAZULR010000000
VERSION     DAZULR010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1536
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.146"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..>1536)
                     /locus_tag="ACG8ZV_002847"
     rRNA            complement(<1..>1536)
                     /locus_tag="ACG8ZV_002847"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          321 a          476 c          337 g          402 t
ORIGIN      
        1 gggaaatctc atcttgaggt gggcttcaca cttagatgct ttcagcgttt atcccttccc
       61 tacatagcta cccagcaatg cccttggcag aacaactggt acaccagcgg taagtccatc
      121 ccggtcctct cgtactaagg acagctcctc tcaaatttcc aacgcccgcg acggataggg
      181 accgaactgt ctcacgacgt tctgaaccca gctcgcgtgc cgctttaatg ggcgaacagc
      241 ccaacccttg ggaccgacta cagccccagg atgcgacgag ccgacatcga ggtgccaaac
      301 ctccccgtcg atgtggactc ttgggggaga taagcctgtt atccccaggg tagcttttat
      361 ccgttgagcg atggcccttc catgcggaac caccggatca ctaagcccga ctttcgtccc
      421 tgctcgactt gttggtctcg cagtcaagct cccttctgcc tttacactct tcgaatgatt
      481 tccaaccatt ctgagggaac ctttgggcgc ctccgttacc ttttaggagg cgaccgcccc
      541 agtcaaactg cccatctgac actgtctccc accacgatta gtggtgcggg ttagagtggc
      601 cataacgcag gggtagtatc ccaccagcgc ctccatcgaa actagcgttc cgatttctac
      661 ggctcctacc tatcctgtac atgcggtaca gacactcaat atcaaactac agtaaagctc
      721 catggggtct ttccgtcctg tcgcgggtaa cctgcatctt cacaggtact aaaatttcac
      781 cgagtctctc gttgagacag tgcccaaatc gttacgcctt tcgtgcgggt cggaacttac
      841 ccgacaagga atttcgctac cttaggaccg ttatagttac ggccgccgtt tactggggct
      901 tcaattcgta ccttcgcttg cgctaagcac tcctcttaac cttccagcac cgggcaggcg
      961 tcagccccta tacttcatct tacgattttg cagagacctg tgtttttgat aaacagtcgc
     1021 ttgggcctat tcactgcggc tgatcgtatg atcagcaccc cttctcccga agttacgggg
     1081 tcattttgcc gagttcctta acgagagttc tctcgctcac cttaggattc tctcctcgac
     1141 tacctgtgtc ggtttgcggt acgggccgct gttttctcac tagaagcttt tctcggcagt
     1201 gtgacatcag gaacttcggt actattattt ccctccccat cacagcttgt ccttaagaaa
     1261 agaagcattt gactcctctt cagacttact gcttggacag acatttccga tcgtctgcat
     1321 tccttagcct cctgcgtccc tccattgctc aaacaaaaac aacgggtaca ggaatatcaa
     1381 cctgttatcc atcgcctacg cctgtcggcc tcggcttagg tcccgactaa ccctgggcgg
     1441 acgagccttc cccaggaaac cttagtcatt cggtggacag gattctcacc tgtctttcgc
     1501 tactcatacc ggcattctca cttctaagcg ctccag
//
LOCUS       DAZULR010000138         1444 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.147, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000138 DAZULR010000000
VERSION     DAZULR010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1444
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.147"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(150..1337)
                     /locus_tag="ACG8ZV_002848"
     CDS             complement(150..1337)
                     /locus_tag="ACG8ZV_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HFS4998088.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          422 a          312 c          252 g          458 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttcact tttacacaat tatatggacg
     1441 taat
//
LOCUS       DAZULR010000139         1433 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.148, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000139 DAZULR010000000
VERSION     DAZULR010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1433
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.148"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            4..>1433
                     /locus_tag="ACG8ZV_002849"
     CDS             4..>1433
                     /locus_tag="ACG8ZV_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998089.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQKMTNGQ
                     PMNDKRNGRSWFNQQERIENKVQSLREEIKQQEEYVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESAFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     RPTDSMKEKENDHFYRVEFNENDPEKGLKSYGGEIVTFELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPY"
BASE COUNT          595 a          233 c          318 g          287 t
ORIGIN      
        1 aacatggcag aagaaaaaga accactagac aatagtcgtt tgggaaaatc caaaagaaaa
       61 ctagtacgat tgcaaaatga attaaacgaa caaattgaaa agatgtttga acaccaaaaa
      121 atgacgaacg gtcaaccaat gaacgacaag aggaatggcc gttcatggtt taaccagcaa
      181 gaacgaatcg aaaataaagt ccaaagtctg agagaagaga tcaagcaaca agaagaatac
      241 gtggaaaagc ttgaaagaca agaagagcta aaggaaatgg gctataacaa gtacggcgga
      301 ctggatatga cgatcgataa tattccaaga atcaaagaag aaatcgaacg ctttgaaaaa
      361 ggtgaatcgg ctttttcagc cgccacgatc cgaaaatacc aacggaagtt ggaaacatta
      421 gaacagctga aagaaaaatc agaaaaagga aaagaaaata tcctccctga agtacaagcg
      481 atcattgaca gcggacgagt gacgcaatgg aaaaaaaatc caaccattta ttttttgaaa
      541 ggctatcgaa aagttgcttt agaactgaat gaaaacgggg gatttgagga atcaaaaaaa
      601 taccaagcca cgtcggaaga ggaaaaagca gctgttcgtg aattacttga agaggctaga
      661 ccaactgatt ctatgaagga gaaagaaaac gatcatttct atcgagtaga attcaacgaa
      721 aatgatccag aaaaaggatt gaaaagttat ggtggggaga tcgtaacatt cgaattgatc
      781 gatcaactca aaacattgga taaccaatac gccgcagaag caggttatta taaattctat
      841 tttgaggaag tgaagaacgg agaagtagtc gatcagatcc gaatggatct aggggatggc
      901 gtcaacagta atcaaccaat ctatttagag ttagcaaaat tgtgcgaaca agtacctgag
      961 aaggaacaaa aacaatcggt caaaaatgaa cctgtttcga aagaacaaat gcagtcgaaa
     1021 gaaacaaaaa caaaacaaaa gggctatcaa aaacgaacgg cagaagagat taaacaagaa
     1081 gttaaatccc tttcgcaaca ggcactggat gcggtgaaaa agcataccca ttctcctgaa
     1141 gacgtcaaag aacttttgaa ctttatgtct cgttttccag aacgatcctt tagaaatcaa
     1201 ttattgattg aggaacaatt tccaggtgca acggcttgtt taggtcgtgc cgcgttgaaa
     1261 aaagaaggaa tctatatcaa aaaaggggaa caagggaaca agatctttgt cagaaaaacg
     1321 gtcaaagggt tttatgagaa aggacgtggc tttgttcgag aaacagaagc tacaccagaa
     1381 gataaaaaac gaatcgaaag tggtcaaatc gaagtgatca aaaaacctta cta
//
LOCUS       DAZULR010000140         1432 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.149, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000140 DAZULR010000000
VERSION     DAZULR010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1432
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.149"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            4..1432
                     /locus_tag="ACG8ZV_002850"
                     /pseudo
     CDS             4..1432
                     /locus_tag="ACG8ZV_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622812.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          593 a          225 c          318 g          296 t
ORIGIN      
        1 gtcatggcag aagaaaaaga accactagac aatagtcgtt tgggaaaatc caaaagaaaa
       61 ttagtacgat tgcaaaatga attaaacgaa caaattgaaa agatgtttga acaccagaga
      121 aagaccaacg gtcaaccaat gaacgataag agaaatgggc attcttggtt taggcaacaa
      181 gagcgaatcg aaaataaagt gcatagtctg agagaagaga tcaagcaaca agaaaaacaa
      241 gtagaaaaac ttgaaagaca agaagagata aaggaaatgg gctataacaa gtacggcgga
      301 ctggatatga cgatcgagaa tattccaaga atcaaagaag aaatcgaacg ctttgaaaaa
      361 ggtgaatcga ctttttcagc cgctacgatc cgaaaatacc aacggaaatt ggaaacatta
      421 gaacagctga aagaaagatc ggaaaaagga aaagaaaacc ttcttcctga agtacaagca
      481 atcattgaca gcggacgagt gacgcaatgg aaaaaaatcc gaccatttat tttctgaaag
      541 gctatcgaaa agtcgcttta gaactgaatg aaaacgggga atttgaggaa tctaaaaaat
      601 accaagccac gtcggaagag gaaaaagcag ctgttcgtga attacttgaa gaggctgtac
      661 caactgattt tttgaaggag aaagaaaacg atcattttta tcgagtagaa ttcaacgaaa
      721 atgatccaga aaaaggattg aaaagttatg gtggggagat cgtaacattc gaattgatcg
      781 atcaactcaa aacgttggat aaccaatacg ccgcagaagc aggttattat aaattctatt
      841 ttgaagaagt gaagaacgga gaagtagtcg atcagatccg aatggatcta ggggatggcg
      901 tcaacagtaa tcaacccatc tatttagagt tagcaaaatt gtgcgaacaa gtacctgaga
      961 aggaacaaaa acaatcggtc aaaaatgaac ctgtttcgaa agaacaaatg cagtcgaaag
     1021 aaacaaaaac aaaacaaaag ggctatcaaa aacgaacggc agaagagatt aaacaagaag
     1081 ttaaatccct ttcgcaacag gcactggatg cggtgaaaaa gcatactcat tctcctgaag
     1141 acgtcaaaga acttttgaac tttatgtctc gttttccaga acgatccttt agaaatcaat
     1201 tattgattga ggaacaattt ccaggtgcaa cggcttgttt aggtcgtgcc gcgttgaaaa
     1261 aagaaggaat ctatatcaaa aaaggggaac aagggaacaa gatctttgtc agaaaaacgg
     1321 tcaaaggatt ttatgagaaa ggacgtggct ttgttcgaga aatagaagct acaccagaag
     1381 ataaaaaacg aatcgaaagt ggtcaaatcg aagtgatcaa aaaaacttac ta
//
LOCUS       DAZULR010000141         1411 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.150, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000141 DAZULR010000000
VERSION     DAZULR010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1411
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.150"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            149..910
                     /locus_tag="ACG8ZV_002851"
     CDS             149..910
                     /locus_tag="ACG8ZV_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HFS4998090.1"
                     /translation="MHTPEEIMELSIHLGTKKIHKPILAKLILGFIGGAMISLGYLAY
                     VRVSASIPESMASLTSLVGASVFPIGLLVILLGGGELITGNMMAVAIAFMDKKVTFSQ
                     LVKNWSVITFANIIGAIFVAYFFGHFVGLTHSGVYLDQVIHIADHKIAVSWWQALGSG
                     IGCNWFVGLALWLSYGAKDAAGKVLTIWFPVMIFVAIGFQHSVANCFVIPAAIFEGQA
                     TWLEFLSNFIPVYIGNIIGGAIFVSGFYYVSYKHH"
     gene            1138..1332
                     /locus_tag="ACG8ZV_002852"
     CDS             1138..1332
                     /locus_tag="ACG8ZV_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998091.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
BASE COUNT          465 a          213 c          260 g          473 t
ORIGIN      
        1 ttttagaatc aaatgtgatt aaatagaaaa ttttacaata atatgcacat ataaataata
       61 agatgatata atcaacaaag aaaatgtgat ttttttcact atattttatc acatgaaaat
      121 tcattaagaa agtaggaatc gaagtattat gcacacacca gaagaaatta tggaactcag
      181 tattcatctt ggaacaaaaa aaatacataa acctatctta gctaaactga ttttaggttt
      241 tatcggagga gccatgattt ctctaggtta tttggcatac gtacgagtct ctgcttctat
      301 cccagaatct atggctagct tgactagttt agttggtgcc tcggtttttc ctatcggcct
      361 gctggtcatc cttcttggcg gtggtgaatt gatcaccgga aatatgatgg ctgtggcgat
      421 tgcctttatg gataaaaaag tcacattctc acagctggtt aagaattggt cagtgattac
      481 ttttgcaaat attattggtg caattttcgt tgcctatttc tttggacact ttgttggttt
      541 aactcattca ggtgtctatc tcgaccaagt gattcatatt gctgatcata aaatcgctgt
      601 ttcttggtgg caagcattag gctccggaat aggttgtaat tggtttgtcg gtttagcgtt
      661 atggttatca tatggagcaa aagatgcggc cggcaaagta ctaacgattt ggtttccagt
      721 catgattttt gtggcaatcg gtttccagca tagtgtggcc aactgttttg tgatacctgc
      781 tgccatattt gaaggtcaag cgacttggtt agaatttctc tcgaatttta tccccgttta
      841 tattggaaat atcatcggcg gagctatttt tgtttcaggt ttttattacg ttagttataa
      901 gcatcattaa gattgaaggt aatgttcatt cgagcattac cttcaatctc tttatatact
      961 atttatattt taagaacaat agccttttat tatatatatt attcaaatta gttatatcga
     1021 gtgaaaaaaa ctttcaaatt gattcttttt atttatcata aagatataga tacataatca
     1081 ttttcactta catatatttg aatattaact aaaaacagca agaaagaaga ggatcaaatg
     1141 tattatgtag aagtaaaaac aaaaggcgtc aaaaacaaac aatatgtgaa aggtatcagt
     1201 aacgaatatc ctttacttgg ttcatggaaa gaagctgctc ctttttccaa accatgtgcc
     1261 ataaaaataa agaacgagct agaaaaagaa ctgacttgtg gcaaagctgt tgtagatatc
     1321 atcgaaaagt aaatccaatg tatagaaagg aagatcacac atgaaaagcg acgtacaaat
     1381 tgctaagatt atagaattag aagaagaaga c
//
LOCUS       DAZULR010000142         1393 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.151, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000142 DAZULR010000000
VERSION     DAZULR010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1393
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.151"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            102..>1393
                     /locus_tag="ACG8ZV_002853"
     CDS             102..>1393
                     /locus_tag="ACG8ZV_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFS4998092.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFKLRIMIRHGKTFLT"
BASE COUNT          440 a          276 c          263 g          414 t
ORIGIN      
        1 ggtgaacttc accaacatct tttttgtata aaaaaatata gaaaagacac cctgaaatcc
       61 tttagaatta atttggctac caattcatag gaggattcaa gatgtctcat actcagctta
      121 tcaaagatac cctaaatatt ctagacctaa atatctattt cgaggaaaat tgtttaacta
      181 aagaaaaata caaagggcaa atttgcttga tttacaaagg aactcttctg tacaagccag
      241 aagagtgttc ccattgtctt tgtgtcgtcc cctctaggat cattcgttgg gggacgacaa
      301 ccgttcggtt gttactgaat gatgtgtctg agtatcgcac ttatctggag ctgaagaaac
      361 aacgatttaa atgtaagtct tgccaaagaa cattcgtagc ggatacctct gttgctgaaa
      421 aacactgttt cattagtcaa aaagttcgtt ggtctgtcat tgctcgctta aaagagaata
      481 cttccatgac ggaaatcgct cgtcagaaaa atatttccac ttcttcggtc tatcgtgtca
      541 tgaagcgatt ctaccgccca ttgaatcctt tcaaacagac tttgccaaag gtcttatgct
      601 ttgatgaatt caaatcggtt cgaagtgttg ccagtgcaat gagttttatc atgatggacg
      661 gacaaagcca tgcattattg gatattgtcg aaaatcgacg cttgccttat ttagaacgct
      721 atttttctcg gttttcatta gcgactcgtg aagccgttca attgattgtt attgatatgt
      781 atgcgcctta tgtttcgttg gtgaaaaagc ttttcccgaa tgctcagttg atcatcgatc
      841 gtttccacat cgtccaacat attggcagaa ctttcttgaa tcatcgagtg aaagaaacca
      901 cggtacgact taaaggaaat tcccactctc aacgagggtt agggaaaaaa ttgaagcgct
      961 attggaaact cctacaaaaa gaagaagcaa agttaaacta tgaaaaacgg gtttggcgtg
     1021 ccagttttaa agattatttg actgaaagtg agattgccga tcgactgtta gctgcttgtc
     1081 ccaacttacg ccaaggctat cagttatacc aagacattct ttatgcggta aagaaaagag
     1141 atcagtcact atttgaggat tgtttaacta gagacattag cggtctgcca gaaacctata
     1201 caaccacttt acgaacgttt aaaaagtttc tgccacagat ccaaaatgcg cttcactaca
     1261 gctattcaaa cggaccattg gaatgcttaa acaaccacat caaagtatta aaacgcaatg
     1321 cgtacggctt tcgcaacttt tacaatttca aactacgaat tatgattcgt catggcaaaa
     1381 catttttaac caa
//
LOCUS       DAZULR010000143         1368 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.152, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000143 DAZULR010000000
VERSION     DAZULR010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1368
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.152"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            82..>1368
                     /locus_tag="ACG8ZV_002854"
     CDS             82..>1368
                     /locus_tag="ACG8ZV_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HFS4998093.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQLIN"
BASE COUNT          467 a          263 c          257 g          381 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg atcaatcaat taatcaat
//
LOCUS       DAZULR010000144         1275 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.154, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000144 DAZULR010000000
VERSION     DAZULR010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1275
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.154"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(31..1203)
                     /locus_tag="ACG8ZV_002855"
     CDS             complement(31..1203)
                     /locus_tag="ACG8ZV_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS1542 family transposase"
                     /protein_id="HFS4998094.1"
                     /translation="MTQVHFTLNNEEVQSIIEHSVKDDVSKNILTTVFNQLMENQRTE
                     YIQADDYERSESRQSQRNGYYERDFTTRVGTLELKVPRTRDGEFSPTVFERYQRNEKA
                     LLASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLDPMVNEWQNRSLSGTN
                     YPYLMTDVLYIKVREDHRVLSKSCHIAIGITEGGDREIIGFMIQNEESDDTWSIFFEY
                     LKERGLKGTELIISDAHKGLVSAIRKSFTNASWQRCQVHFLRNIFSSIPKKNSKPFRE
                     AVKAIFKFTDIELARTAKNALVGEYIDQPKYTKACEILDNGFEDAFQYTVIGNSHNRL
                     KSTNLLERLNQEVRRREKIIRIFPNRTSANRLIGAVLMDLHDEWLSSTRKYIKFDQ"
BASE COUNT          345 a          265 c          245 g          420 t
ORIGIN      
        1 taaaatacta tacaatgttt taccggtctc tcattgatca aacttaatat attttcttgt
       61 agaactgagc cattcgtcat gaaggtccat aaggacagct ccaattaatc gattggcaga
      121 cgttcggttg ggaaaaatcc gaataatctt ttctcttctg cggacttcct ggttcagtcg
      181 ttcaagaagg ttggtgcttt ttagccgatt atgactattt ccgataaccg tgtattgaaa
      241 ggcatcttcg aagccattat ccaatatttc gcaggctttt gtatatttag gctggtcgat
      301 atattcaccg actaaggcat tcttagctgt tcgagcgagt tcaatatccg taaacttaaa
      361 gatcgctttt actgcttctc taaacggttt tgaattcttt tttggaatgg aactgaagat
      421 gtttcttaaa aaatggacct ggcatctctg ccaacttgcg ttggtaaatg acttacgaat
      481 cgcagacact aggcctttat gggcatcaga aatgatgagt tctgtcccct ttaggccgcg
      541 ttcttttaag tattcaaaga agatggacca tgtgtcatca ctttcttcat tttgaatcat
      601 gaagccaatg atttcacggt cgccaccttc tgttatcccg atcgcaatat ggcagctttt
      661 agaaagcact cgatggtcct cacggacttt tatgtagaga acatcagtca tcagataagg
      721 ataattcgta cctgagagtg aacggttctg ccattcgttg accatcgggt ctaactgctc
      781 agtcaggcta gaaacaaaag atttcgatac agattttcca catagctctt caacaatctt
      841 tgaaacttta cgtgtcgaaa cgcccgaaac atacatctca agcattgaag cgagcagtgc
      901 cttttcattt cgctgataac gctcaaacac cgtcggtgaa aattcaccat cacgtgttct
      961 aggcactttt aattcgagtg tacccacacg agtcgtaaag tctcgctcat aatagccatt
     1021 tctttgactc tgacgacttt ctgaacgttc atagtcatcg gcttgaatat attctgttcg
     1081 ttgattttcc atcaattggt tgaaaacagt ggttaaaata tttttagaaa catcatcttt
     1141 taccgaatgt tcaataatac tttgaacctc ttcgttgttc agtgtaaaat gtacttgggt
     1201 catgtaacgt cctcctgggt atgtttttgt ggttaaaaac attgtaccgt aaaagggctg
     1261 ttacatggcc tttta
//
LOCUS       DAZULR010000145         1263 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.155, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000145 DAZULR010000000
VERSION     DAZULR010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1263
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.155"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            47..106
                     /gene="ermCL"
                     /locus_tag="ACG8ZV_002856"
     CDS             47..106
                     /gene="ermCL"
                     /locus_tag="ACG8ZV_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002497446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methylase leader peptide ErmCL"
                     /protein_id="HFS4998095.1"
                     /translation="MGIFSIFVINTVHYQPNKK"
     gene            166..900
                     /locus_tag="ACG8ZV_002857"
     CDS             166..900
                     /locus_tag="ACG8ZV_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011282421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(T)"
                     /protein_id="HFS4998096.1"
                     /translation="MNKKNIKDSQNFITSKHHINEILRNVHLNTNDNIIEIGSGKGHF
                     TFELAKRCNYVTAIEIDPKLCRITKNKLIEYENFQVINKDILQFKFPKNKSYKIYGNI
                     PYNISTDIIRKIVFESTATESYLIVEYGFAKRLLNTNRSLALFLMTEVDISILSKIPR
                     EYFHPKPRVNSSLIVLKRHPSKISLKDRKQYENFVMKWVNKEYIKLFSKNQFYQALKY
                     ARIDDLNNISFEQFLSLFNSYKLFNR"
BASE COUNT          468 a          197 c          191 g          407 t
ORIGIN      
        1 gcttgtgcta taattattct aatttcataa aaaggagaat taatatatgg gcatttttag
       61 tatttttgta atcaacacag ttcattatca accaaacaaa aaataagtgg ttataatgga
      121 ttgttaatat aaacattcat tataacctca taggagtggg ttataatgaa caaaaaaaat
      181 ataaaagata gtcaaaactt tattacttca aagcatcata taaatgaaat tttgagaaat
      241 gtacatttaa atacaaatga taatattatt gagattggtt cagggaaagg tcatttcacg
      301 tttgaattag ctaaaaggtg taattatgta accgccattg aaatagatcc taaattatgt
      361 aggataacta aaaacaaact tattgaatat gagaacttcc aggttatcaa taaagatatt
      421 ttacaattta agtttcctaa aaataagtca tataagatat atggaaatat accctacaat
      481 ataagtacag atataattcg aaaaattgtt tttgaaagca cagctacaga aagttattta
      541 atagtggaat atggatttgc taaaaggttg ctaaatacaa atcgttcact agcactattt
      601 ttaatgacag aagttgatat atccatatta agtaaaatcc ctagagaata ctttcatcca
      661 aaacctagag ttaatagctc gttaattgta ttaaaaagac acccttcaaa aatatcactc
      721 aaagatagaa aacaatatga aaattttgtt atgaaatggg ttaacaaaga atacataaaa
      781 ctattttcca aaaaccaatt ttatcaagcc ttaaaatatg caagaattga cgatttaaac
      841 aatattagct ttgaacaatt cttgtctctt ttcaatagct ataaattatt taatagataa
      901 gttaaggggt gcataaactg catcccttaa cttatcttat tttgcttaaa caatcttggc
      961 ccgtaaactg cataactcat atgtaaatcg ctccttttta ggtggcacaa atgtgaggca
     1021 ttttcactat ttccggcaat tacttccatg taaagtataa cccactatac tttgcaagca
     1081 aagtgtgggc tcgccgaggg gtcttgcaga cggctctttc ggctcttttg agccgagtat
     1141 cagcgcaccc ttatggtgca attagctgat acctgtttga cgatttgctg ccctaccttt
     1201 tcggtaggta tgcaaacctc aaaccaaaat aaaaaccccc ttcgacttcg tcagggggtt
     1261 ttt
//
LOCUS       DAZULR010000146         1246 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.156, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000146 DAZULR010000000
VERSION     DAZULR010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.156"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            200..742
                     /locus_tag="ACG8ZV_002858"
     CDS             200..742
                     /locus_tag="ACG8ZV_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998097.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            898..>1246
                     /locus_tag="ACG8ZV_002859"
     CDS             898..>1246
                     /locus_tag="ACG8ZV_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="HFS4998098.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMP"
BASE COUNT          514 a          141 c          238 g          353 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tctggatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccag
//
LOCUS       DAZULR010000147         1205 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.157, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000147 DAZULR010000000
VERSION     DAZULR010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1205)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1205)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1205
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.157"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            330..1175
                     /locus_tag="ACG8ZV_002860"
     CDS             330..1175
                     /locus_tag="ACG8ZV_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFS4998099.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
BASE COUNT          453 a          140 c          200 g          412 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tctttttttg tttaaatctt ttgctaagtt
       61 gaactaatag agtcttttat gaatatcgaa gttagttttt cacctaactt cgttttttat
      121 agttggttat tataaaatag taatatagct gatttggatt caattcatat ttatttataa
      181 atcaaaaata cagagaatag tatataaatg tcctttccta ttcttaaaat gatgtttgta
      241 cttacttaaa ttaggtataa ttagtatatg ttttgtgaga aatttagact tacaataagc
      301 agtgaattta taatcaacgt ataggagaca tggatgaaat gaaactaatt ggtatagatt
      361 tagacggtac tcttttgaat tctgaccaga gcattagtca aaaaaatgca agaacaatga
      421 aacatttacc ggaagactgt tttccattca tttgttctgg aagagaagta gaagacatta
      481 ataatattct caaaaaatct ggtttaagga taccagcagt agggttaaat ggttctgttg
      541 gatttgatgg agaaaaaaag atatttgagt cttccttcga taaaaatgat gtaaaaaaaa
      601 ttgattctgt cctatcgaaa tttccaacca aaatatatac aaatctcgga agttatgaat
      661 ctcagaatta taaaaataaa atgaaaaaaa tttttcacga ggtagggagt gaattttcta
      721 tcaaagagct aaactatgag cttgagtatg aaaaatctat ttgttcaatc ccttataata
      781 atattgagga aattatagaa aaggatgcta tcagcattta caaatttttt atttttattc
      841 ctaatcgtca attgaaagct aatatattta accatttgaa aaagatgcta aatgtgtctg
      901 ttactgaatc ggcacctgta aatattgaaa tcgtacctca aaatgtatct aaaggtgtgg
      961 tgtttgatcg tttggaatca atctacaatt taaagaaacc tttgagaatc gcgatcggag
     1021 atagtttaaa tgacttatct atgtttgaaa gtgcagatat tagttttgca atgggaaata
     1081 gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt ttcaaatgat aaagacggag
     1141 tatctcaagc atttgaaaga attcttacca tataaactaa ttaaggtagt atagaacata
     1201 gaatt
//
LOCUS       DAZULR010000148         1185 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.158, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000148 DAZULR010000000
VERSION     DAZULR010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1185
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.158"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..837
                     /locus_tag="ACG8ZV_002861"
     CDS             <1..837
                     /locus_tag="ACG8ZV_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HFS4998100.1"
                     /translation="TGINCDIDYAKSEMKQIRMLYGKDDRVQAHLLIQSFRPGEITAE
                     KANQLGAEYAKKIAPDHQIAIYTHTDKDHIHNHIVINSVNLETGNKFQAHGQAFLNKC
                     YDLNDEICLEHDLTITERGKKPEKRTMSEIKLKEKNEPVWKDEIRFAIDQTMKNKKTR
                     TYNQFCDSLKTFGIHCLNRGKNFTYELIHKKKKVRSNKLGKDYEKETILHELDRRERA
                     YNQQRTNELRRARASIRETAKEVRREQRTLTTEQPEIRPTRRNHDQHVERGADYQQEL
                     SF"
     gene            797..1075
                     /locus_tag="ACG8ZV_002862"
     CDS             797..1075
                     /locus_tag="ACG8ZV_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998101.1"
                     /translation="MKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDS
                     QVKKFHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
BASE COUNT          471 a          231 c          210 g          273 t
ORIGIN      
        1 acagggataa actgtgacat tgattatgcc aaaagcgaaa tgaaacaaat tcgcatgctg
       61 tatggaaaag acgatcgtgt acaagcacac ttattgatcc agtcttttcg accaggagaa
      121 attaccgctg aaaaagccaa tcaactaggg gcagagtatg cgaaaaaaat agcccctgac
      181 caccaaatcg cgatttacac acatacagac aaagaccata ttcataacca cattgtcatt
      241 aactccgtca atctggaaac tgggaacaaa tttcaagccc atggtcaagc atttttaaac
      301 aaatgttatg acctaaatga cgagatttgt cttgaacatg acttaacaat cactgaacga
      361 gggaagaaac ccgaaaaacg aaccatgtct gaaatcaaat taaaagaaaa aaatgaacct
      421 gtttggaaag acgaaattcg gtttgcgatt gatcaaacaa tgaaaaacaa aaaaactcga
      481 acgtataacc aattttgtga ttctcttaaa acattcggca ttcattgctt gaatcgtggg
      541 aaaaatttta cttacgaatt gatccacaaa aagaaaaaag tacgatccaa caaactagga
      601 aaggattacg aaaaggagac gattttacat gagctggaca gacgagaacg agcctacaat
      661 caacaacgaa ccaacgagct acgaagagct cgagctagca ttcgcgaaac tgcaaaagaa
      721 gtacgaagag aacaacgaac tcttacgact gaacaaccgg aaattagacc gactcgaaga
      781 aaccatgacc aacacgttga aagaggagca gactaccaac aagaattatc gttctaaaac
      841 gttacaagac atagaaaatg aaataaagaa acaacgtgct tttcttgcac cttataccaa
      901 agaaagaata caaactacaa ttgattcaca agtcaaaaaa ttccaccatg cgctattaaa
      961 ccagcgaaat aaagaacaga aaaaagtaat tatgcagcga tcaatggata ttcttgcccc
     1021 cttatgttgc ttaatcatga cactgttagc cttttggctg gtatggggag aataaataga
     1081 aatggcattc tatttaccct atctactcat ttttgccagt attttaggaa ttatttggct
     1141 tagctataag gcttatcaaa caagatattc attaaaaggc tctaa
//
LOCUS       DAZULR010000149         1158 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.159, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000149 DAZULR010000000
VERSION     DAZULR010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1158
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.159"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            116..1135
                     /locus_tag="ACG8ZV_002863"
     CDS             116..1135
                     /locus_tag="ACG8ZV_002863"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HFS4998102.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
BASE COUNT          407 a          183 c          260 g          308 t
ORIGIN      
        1 aagtaaaaac gataaaagaa gtaaacaaac acttaaaaac aatggaaatt agtcccaact
       61 ttaagaaatg tatactataa tggaaattat caattattta tttggaggaa tatccatgaa
      121 acaaaaaatc gcagttcttg gtcctggatc ttggggcact gctttagcac aaacattggc
      181 agaaaacggg catgatgtcc gtatttgggg aaatgtacct gaacagattg atgaaatcaa
      241 taagtatcat acaaatcagc attttttacc tgatttgacg atcccagaat cgattatcgg
      301 atataaagaa ttggcagaag cagtggataa cgcagatgct attttatttg ttgttccaac
      361 aaaagcgatt cgttcagtcg cacaggaact tattggtaaa atgaatacta agccaatcat
      421 tatacatgca agtaaaggac tagaacaaga tacgcataaa cgaatctcag aagttttggc
      481 tgaagaaatt ccagaagaaa aaagacaggc aattgttgta ttatctggtc ctagccatgc
      541 tgaggaagtg gcagtacatg atatcacaac aattacagct gcaagtattg atcaaaaagc
      601 agcagcctat gtacaaaaac tgttcatgaa tgattatttc aggatttata caaataatga
      661 tgtgattggc gtagaaactg gtgcagcact gaaaaatatc attgcaattg gtgccggcgc
      721 tatccatgga ttaggattcg gagatgatgc aaaagcagca atcatgactc gaggattggc
      781 agaaatcagc cgtcttggtg tcgcgatggg tgccaatcct ctgacattta tcggtttgag
      841 tggtgtgggg gacttgatcg ttacttgtac aagtgttcat tctcgcaatt ggcgtgccgg
      901 taacttgtta ggacagggac ataagctgga agaagttcta gaaaacatgg gaatggtcgt
      961 tgagggtgtg gcaacgacaa aagcagcagt agagctagct caacagctag gtgttgagat
     1021 gccaattact caaacaatct ataatgtttt gtataatgga gaagatatca aaaaagcagc
     1081 aaaagaaatc atgttacgtg acggaaaaat ggagaatgaa ttttctcttc gttaaataga
     1141 tgatcaatag ttaatcgt
//
LOCUS       DAZULR010000150         1137 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.160, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000150 DAZULR010000000
VERSION     DAZULR010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1137
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.160"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..355
                     /locus_tag="ACG8ZV_002864"
     CDS             <1..355
                     /locus_tag="ACG8ZV_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998103.1"
                     /translation="GAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETNMTRDELL
                     RKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTTSQIKQDT
                     EDSLRKGWGMNNKVR"
     gene            615..910
                     /locus_tag="ACG8ZV_002865"
                     /pseudo
     CDS             615..910
                     /locus_tag="ACG8ZV_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            985..>1137
                     /locus_tag="ACG8ZV_002866"
     CDS             985..>1137
                     /locus_tag="ACG8ZV_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HFS4998104.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TTIYRWV"
BASE COUNT          431 a          135 c          237 g          334 t
ORIGIN      
        1 tggcgcacca atcagaaagt ttgataaggt ttattccacc aagcatcctt taaaactgtc
       61 gactttgtta aatgcgactt ccagagtttt agtagaaaag tatgagacta atatgacaag
      121 agatgaattg cttagaaaag ctttagatga gtatattaaa cagaatctta cgcaagaaga
      181 taagcaagat ttgtttaatg acgtggtgaa agaactagac ttgttcagag aaaaatatcc
      241 aattgttcca gaattagatg atcgtggaga aataataaga actaccagtc agataaaaca
      301 agataccgaa gactcactgc gcaaagggtg gggaatgaat aataaagtta gataataatc
      361 aaagaagaac taagtaacta cctttaaacg gtagttactt agttcttctt tgatttgcat
      421 gaaatagagg ggatttattt ttctggttac gtgattaaaa aatccaaaaa atgagcatag
      481 gaacggttat gattttaggg tgtgttttaa tgagatattg tgatttcatt aacaagtgta
      541 tgataatctg ttgttgagtt agtaaataag taatagagct aactctaaaa taaaactatt
      601 aggaggagat gtaggtgaaa aagtttaaaa agaaaatata tttaggattg gttgttgggg
      661 tgagtatgtt tgggttcatg gctcatacta aacaagtaac tgcagatact aaccaaaaag
      721 aaaggattat gagccaatta gatgactctc aaataagtat gtacccaatg agctaattgt
      781 cagtttaaag gctacacaaa gaatttcaac agagaaaaat aaaccgcaaa atttattggg
      841 tgtaaaagtt atggtggaaa aagatttgac tcttaggaca aatgaaagcg attgtaataa
      901 gcgagatcaa gggttctgtt gcaaagtttt ccaaaaaatc tattttagtg taaaattgag
      961 aaaaaagaca gagaggacag agtaatgaat cattttaaag gcaaacaatt caaaaaagac
     1021 gtcattattg tcgctgttgg ttactacctg cgttacaatc taagctatcg tgaagttcag
     1081 gaattgttat atgatcgtgg aataaatgtt tgtcatacta cgatttatcg ttgggta
//
LOCUS       DAZULR010000151         1112 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.161, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000151 DAZULR010000000
VERSION     DAZULR010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1112
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.161"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            154..417
                     /locus_tag="ACG8ZV_002867"
     CDS             154..417
                     /locus_tag="ACG8ZV_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFS4998105.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
     gene            417..689
                     /locus_tag="ACG8ZV_002868"
     CDS             417..689
                     /locus_tag="ACG8ZV_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HFS4998106.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            766..1095
                     /locus_tag="ACG8ZV_002869"
     CDS             766..1095
                     /locus_tag="ACG8ZV_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFS4998107.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
BASE COUNT          423 a          141 c          220 g          328 t
ORIGIN      
        1 ctctaggaaa aaattaacta gcaccacggg tataaaggaa acggataaca ctttacaatg
       61 ctgttttggt actccaattt aaacaaaaca atcgaattta cgtacttaat taagtacgtt
      121 agaatggaga tataaattag agggggagta gatatggcaa aaacagtctt aaatcctagc
      181 tcagcacgga aaaattttta taagttgttg aaagatgtaa atgagaatca tacggaaatt
      241 gaaatcatta gtgagcgcag tgaaaataat gcggtgctta ttggtttgga tgattggaaa
      301 gcaatcaaag aaacgctatt acttgagcaa ataggcactt tgggtgttgt tcgtaagcga
      361 gaaaaagatg atagtggatt tactaatgtt gatgaaattg attgggataa cttataatga
      421 ataactattc tgtgatgatt aaaaactcgg ctaaagctga tttaaagaaa atcaaacagt
      481 ctaatttgaa acctcaattt gagaaggtta ttcagacttt aaaggaagat ccctatctcc
      541 ctacccaatc atttgagaag ttaaaaccta cacatgaagg taggtattct agaagattga
      601 atagacaaca ccgggttgtt tataaggtag atgaagatga acacgtggtt gaaatttatt
      661 cagcaaggac gcattacgag tcacagtaat tacttgtaaa tacattatct cgtggtataa
      721 tgtatttact aagtaattac atactgttag aaatgaggga tttaaatgat tacaaaaaca
      781 agaaaacaag gcaattcaat catgttgaca gtacctaaag attttaatgt tcctaatgga
      841 gtcgaagttg aagcaaagtt ggtagagaat ggtattcttt atgaatttgt tgaaccacaa
      901 aaagaatttt atgattttag cgaagatatt ttgtctgata taattgcaga aggctacgat
      961 aaagatgaga ttcttgtaga atttaagaat agaaaaaaca aaatgcattc ttcctttaga
     1021 gatattgctg aagatacact tactaattct aaagtaatga ctaaagagga gttggcaaca
     1081 gaaattggct tatgaaatcg ttccttcaaa ac
//
LOCUS       DAZULR010000152         1091 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.162, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000152 DAZULR010000000
VERSION     DAZULR010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1091
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.162"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            6..980
                     /gene="bsh"
                     /locus_tag="ACG8ZV_002870"
     CDS             6..980
                     /gene="bsh"
                     /locus_tag="ACG8ZV_002870"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HFS4998108.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGETKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          384 a          135 c          187 g          385 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtta ctgttactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctgggctaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaaact aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgatga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgttggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaacatttt ttcttgatgt gatatccttg tcttttttgt
     1081 aatgttttta a
//
LOCUS       DAZULR010000153         1086 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.163, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000153 DAZULR010000000
VERSION     DAZULR010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1086
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.163"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            57..914
                     /locus_tag="ACG8ZV_002871"
     CDS             57..914
                     /locus_tag="ACG8ZV_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFS4998109.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
BASE COUNT          409 a          157 c          232 g          288 t
ORIGIN      
        1 ataaatatgt tataatagta tcaaatgaat attgctaaaa gaaaagaggt aggaacgtgg
       61 tagcgaagaa atatgtaatc ggtaatttta aaggtggcgt aggtaaaagt acgtgcgcgc
      121 aaatgttagg gtttgaatca gcagttaatg aaggaaaaag aaccttgata attgacttgg
      181 atatgcaagg aaatacttct gatgtgatga acttaacgca tatgaacttc actaacgaag
      241 aaggaggcgg agaaggtgaa ccgattgttt acgaaaatac tgtgactgac gtgttgataa
      301 acaatcttcc acctaaagag gctgtctata aagtaatcaa taacctctat atacttccag
      361 cagacatgtc ctttgaaatg tatgatgatt ggatcaaaga ccaatataat gattcattat
      421 cccaattcaa atatatgaaa gaaaagctag aaccattatt tgatgagttt gacgtcatct
      481 atttagatgt cccaccttct atttctgtat atagtaaatc cgcgatgtac attgcggatt
      541 gggcaatcgt cgtcttacag acccaagtaa aatcgatgag aaatgcgatg caatatcttg
      601 agtatatgga cttttttgtg aaagaatttg atacaaattt atatgttgct ggtgttattc
      661 ctttcatgtt ggaaagcggt gacgcagtag atcaggaaat gtataaacaa gcccaagaga
      721 tttatgggga acatttgatt aaaaatgttg tactcaaaaa tgcgcgctta aaacgatacg
      781 acggatcagg tattacgatg gagaagacaa agaaaggtct cttaaaacaa tgggatcgca
      841 aaagccacga attatttatc agtattttga aagaattgga agaacacgag aattggtatg
      901 cggaggtgga gtaattggct gacatcaaag gacttgatat ttttgggaac aacaaaggac
      961 tcgccaaaat aaaaaaagaa gcagaagcaa agaaaaagca gcaagcaatt acaccatctg
     1021 aaaataagca attagaagtg caccaagttc aagaaataaa aacttcctcc aatgttgaaa
     1081 gacaga
//
LOCUS       DAZULR010000154         1073 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.164, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000154 DAZULR010000000
VERSION     DAZULR010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1073
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.164"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>1073
                     /locus_tag="ACG8ZV_002872"
     rRNA            <1..>1073
                     /locus_tag="ACG8ZV_002872"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          329 a          214 c          308 g          222 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatctaccca tgtccaggtt gaaggtgcgg
      601 taaaacgcac tggaggaccg aacccacgta cgttgaaaag tgcggggatg aggtgtgggt
      661 agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc
      721 tagcctcgga attgagaatg atggaggtag agcactgttt ggactagggg cccatctcgg
      781 gttaccgaat tcagataaac tccgaatgcc attcattcat atccgggagt cagactgtga
      841 gtgataagat ccatagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
      901 tatgttaagt ggaaaaggat gtggggttgc acagacaact aggatgttgg cttagaagca
      961 gccaccattt aaagagtgcg taatagctca ctagtcgagt gaccctgcgc cgaaaatgta
     1021 ccggggctaa acatattacc gaagctgtgg agtacacctt taggtgtatt ggt
//
LOCUS       DAZULR010000155         1038 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.166, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000155 DAZULR010000000
VERSION     DAZULR010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1038
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.166"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>1038
                     /locus_tag="ACG8ZV_002873"
     CDS             <1..>1038
                     /locus_tag="ACG8ZV_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFS4998110.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKH"
BASE COUNT          361 a          204 c          187 g          286 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacacc
//
LOCUS       DAZULR010000156         1021 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.167, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000156 DAZULR010000000
VERSION     DAZULR010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1021
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.167"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..647
                     /locus_tag="ACG8ZV_002874"
     CDS             <1..647
                     /locus_tag="ACG8ZV_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HFS4998111.1"
                     /translation="LEYVKNGDIRNLENMVFNLSNGIIPSVSGDTIRSEKNYSIIVFE
                     KLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIVYYTKEIGKTKIEH
                     LSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMHITIYNYISKRKIS
                     TAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLGLVDNFNNIS"
     gene            664..>1021
                     /locus_tag="ACG8ZV_002875"
     CDS             664..>1021
                     /locus_tag="ACG8ZV_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998112.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDY"
BASE COUNT          375 a          108 c          186 g          352 t
ORIGIN      
        1 tactggaata tgttaaaaat ggagatattc gaaatttaga aaacatggtt tttaatctga
       61 gtaatggaat aattccaagt gttagtggag atacgattcg gtctgaaaaa aattattcta
      121 tcattgtttt tgaaaagtta gcacaaacgt ctataacatt aggaatggat ataatagaag
      181 cgtatcaaag tagagatgct ttgatacaag aaaacgaatt agctgtatcg ttacctgagg
      241 tcttaaaagt gagggattct gggattgttt attatactaa ggaaatcgga aaaactaaga
      301 tagagcatct ttctccctta atttcttctg tcgttcaatt catcggctta aatatctata
      361 aaagaattac tgtaaaggaa atagctaatt atttttctgt aagtgaaact aaattaagag
      421 aaagctttaa gaatgaaatg catattacga tttataatta tatctctaag cgaaaaattt
      481 ctacggctaa aataatgttg aaatcaaacc atactatcag tgaagtttct ttaggtttag
      541 gattttcaga ttcttcacac ttttcgagag tattcaaaaa gtacgcaggt gtatctccta
      601 agcaatatca attaggttta gtggacaatt tcaacaacat tagctgagag gttttatttt
      661 attatgagac tatatcattt acgtagtttg gaggagttga ggaaattgga ttttaacaaa
      721 aaattttttt gggaaatttc tgatttgagt tgtttcgtag aatctgagcg tctaagtaat
      781 ggtaataata gtgtgttaaa tgaatatgac aaagtagtaa ttaataaagt aaaaagttta
      841 tgtgaagaag ctagagaatc tatcagtcat attaatggta gcaattttaa acaaacatta
      901 tttaatctga ttaagctaga tgctaaaata tcaagttatt tattcttttt gatacatgat
      961 gaatttatgg attatcaaaa attggatcag ttaattgaaa gagaaagctg ggaagattat
     1021 t
//
LOCUS       DAZULR010000157         1002 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.168, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000157 DAZULR010000000
VERSION     DAZULR010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1002
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.168"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            369..1002
                     /locus_tag="ACG8ZV_002876"
                     /pseudo
     CDS             369..1002
                     /locus_tag="ACG8ZV_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          343 a          182 c          182 g          295 t
ORIGIN      
        1 tttcaaagtt agtagagaaa atgtagttat atatttaaat ttttaccaga aagaaatgaa
       61 caccttcaat tatctaaatc tcgaaaatgg ttagatgtaa tcatcaggaa aaacaatctt
      121 aaacgaatta ctattcatgg tcttagacac acacatgcta gcttgctttt agcaagctag
      181 tgcaaatatt aaagatgtgc aagagcgttt aggccactct tctattcaaa tcattatgga
      241 tctatatatt catattacag acaaaagaaa agaagaaacc gtagcgcaat tcgcaaaata
      301 taggctctat aatttatggg actgatgaat caaaattgat tcttcagtcc cattgttatt
      361 ttaggtatat gattcgtaca ttgaaagagt tgaaaaacta tcttccgaag ccgtcaaaaa
      421 ggaccctgcc aaaagtattg atggtggatg aatttcgttc gcacgcttca attgtggata
      481 aaatgagctt tatttgtgcg gatggcgaga ctggaaaact cattgatatt ttgcctacac
      541 gaaaattgtc tcgattaaca cactatttta gtcgctgtgc aaatcctgaa gcggtggaat
      601 atttagtgac agatatgaac gccgcctact tccaactgac aaaacgtgtc ttaccaaatg
      661 cgaaagtcgt cattgattgt tttcatatca tcaaacattt gaatcaggcg ttcaatgatt
      721 ttcgtgtaca agaaatgaaa agattacacc agttagggca acgacgggaa gccgagaaag
      781 tgaaaaagaa ctggcgcttt cttctaaaaa accgtcaaaa aatcaatcac tatgattaca
      841 aaacatggcg cagttttcgt gcacctaaat acccactact cactgaagca atgatgattg
      901 atcgattgct ggcattttca acgcctttaa aggacgccta tacttttttc catgagctga
      961 ccgaagcctt tagagacaag gaatcagact tattttttac ct
//
LOCUS       DAZULR010000158          994 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.169, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000158 DAZULR010000000
VERSION     DAZULR010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..994
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.169"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..>994)
                     /locus_tag="ACG8ZV_002877"
     rRNA            complement(<1..>994)
                     /locus_tag="ACG8ZV_002877"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          209 a          307 c          225 g          253 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc aggcggagtg
      361 cttaatgcgt tagctgcagc actgaagggc ggaaaccctc caacacttag cactcatcgt
      421 ttacggcgtg gactaccagg gtatctaatc ctgtttgctc cccacgcttt cgagcctcag
      481 cgtcagttac agaccagaga gccgccttcg ccactggtgt tcctccatat atctacgcat
      541 ttcaccgcta cacatggaat tccactctcc tcttctgcac tcaagtctcc cagtttccaa
      601 tgaccctccc cggttgagcc gggggctttc acatcagact taagaaaccg cctgcgctcg
      661 ctttacgccc aataaatccg gacaacgctt gccacctacg tattaccgcg gctgctggca
      721 cgtagttagc cgtggctttc tggttagata ccgtcaaggg atgaacagtt actctcatcc
      781 ttgttcttct ctaacaacag agttttacga tccgaaaacc ttcttcactc acgcggcgtt
      841 gctcggtcag actttcgtcc attgccgaag attccctact gctgcctccc gtaggagttt
      901 gggccgtgtc tcagtcccaa tgtggccgat caccctctca ggtcggctat gcatcgtggc
      961 cttggtgagc cgttacctca ccaactagct aatg
//
LOCUS       DAZULR010000159          811 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.171, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000159 DAZULR010000000
VERSION     DAZULR010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..811
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.171"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..672
                     /locus_tag="ACG8ZV_002878"
     CDS             <1..672
                     /locus_tag="ACG8ZV_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HFS4998113.1"
                     /translation="SGKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDN
                     NKFTSKMEKKLKREQRKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTD
                     FLNKLSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRK
                     IIKVDKWFPSSQICSECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLH
                     SMGLA"
BASE COUNT          298 a          126 c          152 g          235 t
ORIGIN      
        1 agcggtaaat actatatttc tttgttgtgt aaagaagaaa ttatcgaatt acctaaaact
       61 aattccacaa ttggtattga cttaggtatt atggactttg cgattctttc tgatggacaa
      121 aaaattgata ataataaatt cacgtccaaa atggaaaaga aactaaagcg tgaacaacgc
      181 aaattgtcta ggcgtgcttt attggctaaa aataaaggta ccaatctatt tgaagctaaa
      241 aattatcaaa aacaaaaacg caaagtagct agattgcatg aaaaagtaat gaatcaacgt
      301 actgattttc tgaataagtt gagtacagaa atgatcaaaa atcacgatat tatctgtatt
      361 gaagacttaa acacaaaagg tatgttgcga aatcataaat tagctaaaag tatttctgat
      421 gtttcttggt caaagtttgt gactaaatta caatacaagg ctgactggta tggacgaaaa
      481 atcatcaaag tagataaatg gtttccgtct agtcagattt gttcagagtg cggacataaa
      541 gatggcaaga aatctcttga aattcgagaa tggacttgtc ctgtttgtca tactcatcat
      601 gatcgtgata tcaatgctag tatcaatatt ctgaccgaag gtctaagact acattctatg
      661 ggattggctt agatccaatc atcaagaacc gtaggaacta cggggatagc ttggtaaata
      721 agagacaccg ctgttagtaa agaaatacgc tatcaagtat gctctattcc caagaagctc
      781 ccacttcaag cgttaagaac cgtcaggttt a
//
LOCUS       DAZULR010000160          787 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.172, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000160 DAZULR010000000
VERSION     DAZULR010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..787
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.172"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            363..761
                     /gene="spxA"
                     /locus_tag="ACG8ZV_002879"
     CDS             363..761
                     /gene="spxA"
                     /locus_tag="ACG8ZV_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SpxA"
                     /protein_id="HFS4998114.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT          296 a          108 c          139 g          244 t
ORIGIN      
        1 aagaacagta ttatttaaaa tgacagaaaa cattactatt aaagaaataa aaaacataaa
       61 aaatcttaag aaatcggttt catttagctt ttgagataaa ataatagtac agttttatac
      121 gctgtttcat atgtttagaa aatttgaatt agatttgaaa actctaattt ttaaatgata
      181 aaaaaagcga gaatgctggt tttactgtat attaacctta gataactttc atttttttaa
      241 aaaaattatg aaaaaaaggt agctatttaa aagttgatta tgtataatag aaacagatgg
      301 gagattatta tgatcttctg ttacaaaaaa gtgattctta tcacgaaaag gagtggtgca
      361 cgttgttaac attatatact tccccaagtt gtacttcctg cagaaaggct cgtgcgtggt
      421 tgcaagaaca tcagattcca tttgttgaac gtaatatttt ttcagaacca ttgaacagtt
      481 ctgaattaaa agcgatttta caaatgacag aagacggaac agaagaaatc atctcgacac
      541 gttccaaagt attccaaaaa ctgaacatgg atttagatga tctgccgtta caagaattat
      601 tggaacttgt gcaaaacaat cctggattgc ttcgccgtcc aatcatgatt gatgataaac
      661 gtctgcaagt tggttttaat gaagatgaaa ttcgtcggtt cctaccgcgc gatgtacgac
      721 aattagaatt acgtcaagca caattgatgg ctggattata gaaggataat acgaaacttg
      781 gaaaaga
//
LOCUS       DAZULR010000161          765 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.173, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000161 DAZULR010000000
VERSION     DAZULR010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..765
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.173"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..276)
                     /locus_tag="ACG8ZV_002880"
     CDS             complement(<1..276)
                     /locus_tag="ACG8ZV_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4998115.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDV"
BASE COUNT          259 a          128 c          128 g          250 t
ORIGIN      
        1 gacgtcaggc gtccaaccaa gagtgacttt ctctttaatg taatctactt catgagcagg
       61 taattgaatg acttttctac cacatttttt cttattttct ttatactggt gccaataatc
      121 aagagcagtc ttgccttgct tgaacttatt gactacatta taaatagttt gtatagcacg
      181 tcccattcgg ttagcgattt caaccggctt attatgttga agataatatg attctatcat
      241 tgtcagttcg tctatggtaa gatgtttgta ggtcatttat ggttacactc ctttgttttc
      301 tttcgtcgga aatacaattt gagtgtacca taaatgcctt tttatttttc taacttaatt
      361 ttacaattcg cgatatatta aacaacgttg tcgcgcttca ttgaaacatt ttatgaaaat
      421 tccaaaaaag agttgacaca tgtttttaga cgtgataaga taactaagtc gttaaaaaga
      481 accacttgcg aagcttgatt ctatcgaaaa aaaacttcaa aaaagttctt gacaaataac
      541 aaacgataag ttatgataaa tgagttgctg aaagatttcg aaaaacgaaa tcgaaaaaaa
      601 cttttaaaaa agagttgaca atcgcttgtc tctctgatat gatataaaag ttgctacggc
      661 agccaaaaac gaatcgggaa acactcccga tgaagtagat ctttgaaaac tgaacaaagt
      721 aagacaaacc aaatgtgtag ggcgtcttga ttcaattcaa gacaa
//
LOCUS       DAZULR010000162          755 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.174, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000162 DAZULR010000000
VERSION     DAZULR010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..755
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.174"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(150..440)
                     /locus_tag="ACG8ZV_002881"
     CDS             complement(150..440)
                     /locus_tag="ACG8ZV_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HFS4998116.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            complement(576..>755)
                     /locus_tag="ACG8ZV_002882"
     CDS             complement(576..>755)
                     /locus_tag="ACG8ZV_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998117.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLYI"
BASE COUNT          261 a          123 c          111 g          260 t
ORIGIN      
        1 gcgagcagca actagaataa tttaaacatt attaaactgt ctatattgtt actaataatt
       61 cccttcttat agtgcatttt cttagaaaaa aacaatatta cgatatcatg atattaagat
      121 atcgtaatat tatacaattg tgattgatat tatatatgtt tttttatttt tttatcatgt
      181 ttaatcttga aggaatcata ttctttttct aaagacagga gcttttcata aacatcagac
      241 atgtttaaac tagaggccag gcttaaatca taaacgaatg aagcaggtaa tgattttatt
      301 ctacgttgtc gggttatcca gcttgcaacc gttccttgtg ggtaggcata taactcacaa
      361 aattgttcta cagtgattcc taaattcttg ataatgtaaa cattgatcgg gtgcgagtaa
      421 acaaatgtat tgatagacat ggtgcgtaag cctactttct tttattattg cgtttgcaat
      481 aatagtttaa cacacgcatt attctagtat ctactcctat ttgtaaaaac aaaaaaggat
      541 tcatagagat aactctatag aatccgtaaa ataccttata tatataacgg gaaaatataa
      601 aacctaaaat tatgataacc tgctgcagct tctacataga aagagaagcg ctcaacacca
      661 acctcattta tcaaacgttg gccataaccc caaatctctt ctgatagctg atcaaaggtt
      721 atatacttta gctcatattg ctggataatg ttcat
//
LOCUS       DAZULR010000163          707 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.175, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000163 DAZULR010000000
VERSION     DAZULR010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 707)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 707)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..707
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.175"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..598
                     /locus_tag="ACG8ZV_002883"
     CDS             <1..598
                     /locus_tag="ACG8ZV_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFS4998118.1"
                     /translation="MKKEFPIPISWTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVG
                     GGALQEGRFIEGFSHPEMGHMLVVPHPKDDFAGSCPFHGNCLEGMAAGPAIEKRLGKK
                     GQEVAEDDPYWEIEASYIAQCAYNTTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLV
                     NGYVETPELSKYIVTPALEDNAGTLGCLALAREAVLHS"
BASE COUNT          199 a          139 c          180 g          189 t
ORIGIN      
        1 catgaaaaaa gaatttccga tcccgatttc ttggacaaca gatgtcaatg cggctgccta
       61 tggtgagtat gtcttcggca gtggcaaagg attgagcagt gtcgtttact atacgatcgg
      121 tacgggtgtt ggcggcggtg ccttacaaga agggcgcttt atcgaagggt ttagtcatcc
      181 agaaatgggg catatgctcg tcgtccctca tccaaaagat gactttgctg gcagctgtcc
      241 atttcatggc aactgtttag aagggatggc cgctggaccc gccatcgaaa aacgcttagg
      301 gaaaaaagga caagaggttg cagaagatga tccttattgg gaaatcgaag cctcctatat
      361 tgctcaatgt gcctacaata caaccttgat gttttctcca gatgtgatca tttttggcgg
      421 tggtgtgatg aaacaacgcc atatgctgca aaacgtccac gacgcatttg caaaattggt
      481 caatgggtat gtcgaaacac ctgagttaag caaatatatc gtgaccccag cattagaaga
      541 caacgctgga acgctcggtt gtttggcatt ggctcgagaa gcggtcttac attcataaac
      601 gaaaaaaggc tcttcgacat ttagtgttgg tagagaaaga tacaactgaa aatttagtca
      661 taaccagtta ggcagagtgc ttaactggtt tttgttttac ttggaag
//
LOCUS       DAZULR010000164          696 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.176, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000164 DAZULR010000000
VERSION     DAZULR010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..696
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.176"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(53..628)
                     /locus_tag="ACG8ZV_002884"
     CDS             complement(53..628)
                     /locus_tag="ACG8ZV_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytS/YhcK type 5TM receptor domain-containing
                     protein"
                     /protein_id="HFS4998119.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
BASE COUNT          229 a          151 c          125 g          191 t
ORIGIN      
        1 atgaaaaaac agagccagat tagcattatt ttgctaatcc agctctgttt attcagccta
       61 tttttctttt tgaatatatc aagcgttggg gcaacatagt gatgactaat gaaacaacga
      121 cgatagacaa caagcgatca aggtagtctg tacccgcctg taccaagatc acacttgttg
      181 tctgacttaa acctaaccca tgtaatagct gaacgatcat actggatcct gaggaggtga
      241 tcccgccaaa taactgaacg gtaatgatcg aagaaacgat cgttccaggt accgacaaaa
      301 tcaaagcgag taataacagt ttcaagctgt ttttatcttt gccgagatat cttggcaaaa
      361 tcaatccagc aagcaagcct gtgagaattt ggattggcga ataatacaga gaaaaaatat
      421 ctgtagtcac tccacttaaa ataccgctgg acaatcctgt cagcattcca ggtacaggcc
      481 caagcaatgc accagcaaaa atcgttccga tagaatcgag atagattggc aaacgaagcc
      541 ataaagcaat cgttcctcca atataattga tcccaataca caaagccatc actgtaagta
      601 cgcgagttgc cattttgttt ttattcattt tgttagccca tctttaacct ttccaaatct
      661 ttcataatcg tttcttcttg tgcatttaaa agaacg
//
LOCUS       DAZULR010000165          640 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.177, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000165 DAZULR010000000
VERSION     DAZULR010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..640
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.177"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..283
                     /locus_tag="ACG8ZV_002885"
     CDS             <1..283
                     /locus_tag="ACG8ZV_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFS4998120.1"
                     /translation="LIQDDLHHTHRLWLMNKINLYFGHSYVFAFYDYRTNITEVDLVI
                     SNYYIDTGKTPLLLMKNIPTERNWRLFEKTIYQLKKEKEVVKSAFCPEY"
BASE COUNT          218 a           89 c          119 g          214 t
ORIGIN      
        1 tttaatacaa gatgatttac accatacgca tcggttatgg ttaatgaata aaattaatct
       61 gtattttggg cattcttatg tttttgcttt ttatgattac aggacaaata taactgaagt
      121 agatttggtt atttctaatt actacatcga cactggaaaa acgccattac tgttaatgaa
      181 aaatatacct accgaaagaa actggcgttt gttcgagaaa acgatttatc aattgaaaaa
      241 agaaaaagag gttgtgaaat cagcgttttg tcctgagtat tagagaaaca aacggaaaaa
      301 tagtttttca tattttgccg tttttgagct aataccgagg gacagctgat tgaacaccat
      361 ttattgagag attgtgaaaa aactgtcctg catcaagtaa taagaacagc caagtaaaaa
      421 cagcttctca tgtttgttga atattgtgac ttgtgaccga ggagttggca agagaacacc
      481 gtttattcgg aaaaagggac tgtgacacta catgtcacag tccctttttg attgaattat
      541 ctcatttgtt ttctaatttt ttctttattt gagaaaatag ttgaactgga taaaaagtac
      601 tggacgtgtc aaaattattt tggatcaaat tagatctatt
//
LOCUS       DAZULR010000166          588 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.178, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000166 DAZULR010000000
VERSION     DAZULR010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..588
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.178"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(65..150)
                     /locus_tag="ACG8ZV_002886"
     tRNA            complement(65..150)
                     /locus_tag="ACG8ZV_002886"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(114..116),aa:Leu,seq:taa)
     gene            complement(167..238)
                     /locus_tag="ACG8ZV_002887"
     tRNA            complement(167..238)
                     /locus_tag="ACG8ZV_002887"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(204..206),aa:Gly,seq:gcc)
     gene            complement(250..322)
                     /locus_tag="ACG8ZV_002888"
     tRNA            complement(250..322)
                     /locus_tag="ACG8ZV_002888"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(287..289),aa:Thr,seq:tgt)
     gene            complement(340..421)
                     /locus_tag="ACG8ZV_002889"
     tRNA            complement(340..421)
                     /locus_tag="ACG8ZV_002889"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(385..387),aa:Leu,seq:tag)
     gene            complement(429..501)
                     /locus_tag="ACG8ZV_002890"
     tRNA            complement(429..501)
                     /locus_tag="ACG8ZV_002890"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(466..468),aa:Lys,seq:ttt)
     gene            complement(505..577)
                     /locus_tag="ACG8ZV_002891"
     tRNA            complement(505..577)
                     /locus_tag="ACG8ZV_002891"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(542..544),aa:Val,seq:tac)
BASE COUNT          149 a          169 c          138 g          132 t
ORIGIN      
        1 cccctaacct tttgatccgt agtcaaacac tctatccagt tgagctatgg gcgcatattt
       61 gaaatgccga ggaccggaat cgaaccggta cggtgatcac tcaccgcagg attttaagtc
      121 ctgtgcgtct gccagttccg ccaccccggc gcgattgctt tggcaaagcg gaaaacgggg
      181 ttcgaacccg cgacccccac cttggcaagg tggtgctcta ccactgagct atttccgcgt
      241 gtttaaagat gccggctaaa ggacttgaac cctcgaccct ctgattacaa atcagatgct
      301 ctaccaactg agctaagccg gcatgtaaaa cttaaattat gcgggtgaag ggacttgaac
      361 ccccacgccg taaggcgcta gatcctaaat ctagtgcgtc tgccaattcc gccacacccg
      421 caaaaatatg agccgtacag ggctcgaacc tgtgaccctc tgattaaaag tcagatgctc
      481 taccaactga gctaacggct catatggagg ttaacgggat cgaaccgctg accctctgct
      541 tgtaaggcag atgctctccc agctgagcta aacctccatg gataactt
//
LOCUS       DAZULR010000167          514 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.180, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000167 DAZULR010000000
VERSION     DAZULR010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..514
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.180"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..132)
                     /locus_tag="ACG8ZV_002892"
     CDS             complement(<1..132)
                     /locus_tag="ACG8ZV_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFS4998121.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          186 a           94 c           92 g          142 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaatagcaa attcccgttg gatcctttcc atacatccat tgtactctga
      421 gaaatcacac aatatcgaaa caaattccgt taggaatgtg ttattcaata aattttataa
      481 tctagaaaca ttttgaataa aaactattag acaa
//
LOCUS       DAZULR010000168          494 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.181, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000168 DAZULR010000000
VERSION     DAZULR010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.181"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..325
                     /locus_tag="ACG8ZV_002893"
     CDS             <1..325
                     /locus_tag="ACG8ZV_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4998122.1"
                     /translation="KASLKSLKDTWLDLSEDNPYSQFLITVMAGVNQLERDLIRMRQR
                     EGIELAKKEGKFKGRLKKYHKNHAGMNYAVKLYKEGNMTVNQICEITNVSRASLYRKL
                     SEVNN"
BASE COUNT          197 a           66 c           90 g          141 t
ORIGIN      
        1 aaaggcaagt ttaaaatcac taaaagatac atggcttgat ttatcagaag ataatccata
       61 cagccaattc ttaattactg taatggctgg tgttaaccaa ttagagcgag atcttattcg
      121 gatgagacaa cgtgaaggga ttgaattggc taagaaagaa ggaaagttta aaggtcgatt
      181 aaagaagtat cataaaaatc acgcaggaat gaattatgcg gtaaagctat ataaagaagg
      241 aaatatgact gtaaatcaaa tttgtgaaat tactaatgta tctagggctt cattatacag
      301 gaaattatca gaagtgaata attagccatt ctgtattccg ctaatgggca atatttttaa
      361 agaagaaaag gaaactataa aatattaaca gcctcctagc gatgccgaaa agccctttga
      421 taaaaaaaga atcatcatct taagaaattc ttagtcattt attatgtaaa tgcttataaa
      481 ttcggcccta taat
//
LOCUS       DAZULR010000169          468 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.182, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000169 DAZULR010000000
VERSION     DAZULR010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.182"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>468
                     /locus_tag="ACG8ZV_002894"
     CDS             <1..>468
                     /locus_tag="ACG8ZV_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS982-like element ISEfm1 family transposase"
                     /protein_id="HFS4998123.1"
                     /translation="CVIWGIINGYTSQRATYRAVCSVLFPNGDFPSRSRFTRLSSNLA
                     YTIKIIRYFFIKKLTKGELVGIIDSFPSPLCKPVRNRQAKLLNQIAKVGYNSTKKSYF
                     YGLKIHMIVTKTGFPITYSITNPGVHDVKVLETLSEEANLPNILGDKGYISHK"
BASE COUNT          155 a           86 c           83 g          144 t
ORIGIN      
        1 cttgtgttat atggggcata attaatggct atactagcca aagagccacg tatagagcgg
       61 tttgttccgt cttatttcct aatggtgact ttcctagtag gagtcgattc actcgcttaa
      121 gttcaaactt agcttacact atcaagatta ttcgatactt tttcatcaag aagctcacca
      181 aaggtgaact agtcggaatt atagatagtt ttcctagtcc attatgtaaa ccagttagaa
      241 atagacaagc aaaactattg aatcaaatag ccaaagttgg ctataactca acaaaaaaat
      301 cttattttta tggtcttaaa attcatatga tcgttactaa gactggcttt ccgattactt
      361 actcaatcac gaatccaggt gtccatgacg tgaaagtgtt agagacttta tcggaagaag
      421 cgaatcttcc caatatccta ggggacaaag gatatattag ccataaaa
//
LOCUS       DAZULR010000170          460 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.183, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000170 DAZULR010000000
VERSION     DAZULR010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.183"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..153)
                     /locus_tag="ACG8ZV_002895"
     CDS             complement(<1..153)
                     /locus_tag="ACG8ZV_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HFS4998124.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVREILYDRGINVSH
                     TTIYRWV"
     gene            complement(207..374)
                     /locus_tag="ACG8ZV_002896"
     CDS             complement(207..374)
                     /locus_tag="ACG8ZV_002896"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998125.1"
                     /translation="MIKINQLAGMNIHYLFYSLKEFFAYQQKIGISSVELWGGAPHFF
                     IDAFTGSVAKF"
BASE COUNT          167 a           85 c           71 g          137 t
ORIGIN      
        1 cacccaacga taaatcgtcg tatgagaaac gttaatgcca cgatcatata agatttctcg
       61 aacttcacga tagctaaggt tataacgaag atagtagccc acggctacaa taatcacatc
      121 ctgctgaaat tgctttcctt taaaatgatt catcgtcatt cctcctgcta tctttttcta
      181 ttattctacc ttatttgata gtagatttaa aactttgcaa cagaaccagt aaaagcatct
      241 atgaaaaaat gcggagcacc tccccaaagt tcaacagaag aaataccaat tttctgttga
      301 taagcgaaaa attctttgag agaataaaat aaatagtgga tattcattcc tgctaattga
      361 tttattttaa tcataactat tgcctcctat taatggatga ttaagactaa aagagtgtag
      421 caatgtataa caaaacagca gaaacaaggg ttaagatggc
//
LOCUS       DAZULR010000171          457 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.184, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000171 DAZULR010000000
VERSION     DAZULR010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..457
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.184"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>457
                     /locus_tag="ACG8ZV_002897"
     CDS             <1..>457
                     /locus_tag="ACG8ZV_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HFS4998126.1"
                     /translation="RGINVSHTTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIK
                     IKGKWHYLYRAIDADGLTLDIWLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSIT
                     SAFKKLKEYGFYQGTEHRTIKYLNNLIEQDHRPVKRRNKFYRSLRTASTT"
BASE COUNT          164 a           83 c           86 g          124 t
ORIGIN      
        1 atcgtggcat taacgtttct catacgacga tttatcgttg ggtgcaagaa tatggcaaac
       61 tactctatca aatttggaaa aagaaaaata aaaaatcctt ttattcatgg aaaatggatg
      121 aaacgtacat caaaattaaa ggaaaatggc attatttgta tcgagccatc gatgcagatg
      181 gtttaacctt ggatatttgg ttacgtaaaa aacgggacac acaagcagcc tatgcttttc
      241 ttaagcggtt agtgaagcag tttgatgaac cgaaggttgt agtcacagat aaagccccct
      301 ctattacaag tgcctttaag aaactaaaag aatacggctt ttatcaaggg acagaacatc
      361 gtaccattaa atacctgaat aatttgattg aacaagacca tcgtccagta aagagacgca
      421 ataaattcta tcgaagttta cgcactgcct ctaccac
//
LOCUS       DAZULR010000172          451 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.185, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000172 DAZULR010000000
VERSION     DAZULR010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..451
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.185"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>451
                     /locus_tag="ACG8ZV_002898"
     CDS             <1..>451
                     /locus_tag="ACG8ZV_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFS4998127.1"
                     /translation="FRKGITMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKVR
                     TLNDKYVAIFMDATYIPLKRQTVSKEAIYIAIGIREDGTKEVLSYAIAPTESTYVWNE
                     LLQDIYSRGVHDVLLFITDGLKGMKDTIHQIYPKAKYQHCCVHVSRN"
BASE COUNT          147 a           89 c           87 g          128 t
ORIGIN      
        1 tcttccgaaa aggtattacc atgtcggaaa tcgcagactt gattgagaaa atgtatgggc
       61 atcactacac gccccaaacc atgtccaaca tgactaaagt gctgactgaa gaagtaaatg
      121 catttaaagt tagaactcta aatgataagt atgtcgctat tttcatggat gctacttata
      181 ttccattaaa acggcaaacc gtctccaaag aagcaatcta tattgccatt ggtatacgag
      241 aagacggcac taaagaagta ctaagttatg cgattgctcc gactgaatcg acctacgttt
      301 ggaatgagtt gttacaggac atttactcca gaggggttca tgatgtctta ctgtttatta
      361 ccgatggctt aaaaggcatg aaagatacga ttcaccagat ttatcctaaa gctaaatacc
      421 aacattgctg tgttcacgtt tcccgtaata t
//
LOCUS       DAZULR010000173          443 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.186, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000173 DAZULR010000000
VERSION     DAZULR010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 443)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.186"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>443
                     /locus_tag="ACG8ZV_002899"
     CDS             <1..>443
                     /locus_tag="ACG8ZV_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rib/alpha-like domain-containing protein"
                     /protein_id="HFS4998128.1"
                     /translation="GTTVFAVKDGVSLPEDKLPVLKAKDGYTDAKWPEEATQPITADD
                     TEFVSSATKLDDKSDADKYNPEGQKVTTELNKEPDAFEGIKNKEDLPKDTKYTWKEKV
                     DVSAAGNKKGTVVVTYPDGSSDEVEVDVTVTDNRSDADKYEPTVEG"
BASE COUNT          179 a           67 c          103 g           94 t
ORIGIN      
        1 ggaacaacag tctttgcagt gaaagacggc gtaagcttac cagaagataa acttccagtg
       61 ttgaaagcaa aagatggtta tacagatgcg aaatggccag aggaagcaac tcaaccaatt
      121 acagcagatg atacagaatt tgtatcaagt gcaacaaaac tggatgataa atctgacgct
      181 gacaaatata atcctgaagg tcaaaaagtg actacagaat tgaataagga accagacgca
      241 tttgagggaa ttaagaacaa agaagattta ccaaaagata ctaagtatac ttggaaagaa
      301 aaagtagatg ttagcgcagc tggaaataaa aaagggactg ttgtagtgac atatccagat
      361 ggatcatctg atgaagttga agtagatgtt acagtgacag acaatcgttc tgacgccgat
      421 aaatatgagc caacagtaga agg
//
LOCUS       DAZULR010000174          424 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.187, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000174 DAZULR010000000
VERSION     DAZULR010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.187"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..421
                     /locus_tag="ACG8ZV_002900"
     CDS             <1..421
                     /locus_tag="ACG8ZV_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFS4998129.1"
                     /translation="SLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGNELLD
                     TAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQKRLV
                     FKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
BASE COUNT          159 a           65 c           86 g          114 t
ORIGIN      
        1 atcactagat cgtttaggaa gagattatga agatataaaa aatacagttg cttttatgaa
       61 acagaaaaaa gtagcgttaa aaatattaga tgcacagttt ttagatttta atactggaaa
      121 tgaactcctg gataccgcta tgttcgatat gtttttatca ctgctaagtt atattgcaca
      181 aaacgagcgt gagaaaattc gtgaacgtca gcggcaagga gtattattgg ctcaaaaagc
      241 cggccgatat aagggacgac caatcgagta ttctattaac tcaacagatc cgcaaaaacg
      301 cttagttttt aaaaccgtgg tggacatgtt aaagcaaggc attccagttg cagagattgc
      361 aaaagaaaac gggatctctc gaccaactat ttataaaata aagaaagcga atgatttgta
      421 gaaa
//
LOCUS       DAZULR010000175          415 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.188, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000175 DAZULR010000000
VERSION     DAZULR010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.188"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..339)
                     /locus_tag="ACG8ZV_002901"
     CDS             complement(<1..339)
                     /locus_tag="ACG8ZV_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4998130.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYT"
BASE COUNT          116 a           70 c           68 g          161 t
ORIGIN      
        1 tgtataactc tgaacaggat ttttcttact tttgaaacgt ggaaatccaa cggatttatc
       61 ccgaaaaaaa ttcttgtatg ctttatctaa attaagttgg gcattggcta aagcaaggct
      121 atcaatttct ttcaaaaacg gaaattcttt cttgtattta gctggtgtcg gaaaagtcat
      181 ttttttagaa gaatcatttt taacttcttc atacgccttt tttcggtcat caagcattag
      241 attgtagacc ttacggacac aaccaaaaga tttggcaaag aagatttctt gttcctctgt
      301 tggatagatt ctgaatttgt atgcttttag ttgttccata aagttcacct actttctatt
      361 tatgattgtt tccttgattt tggatatact tcttaatcac atcaattggt gcgcc
//
LOCUS       DAZULR010000176          406 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.189, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000176 DAZULR010000000
VERSION     DAZULR010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..406
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.189"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            1..406
                     /locus_tag="ACG8ZV_002902"
                     /pseudo
     CDS             1..406
                     /locus_tag="ACG8ZV_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          170 a           68 c           76 g           92 t
ORIGIN      
        1 agaaaaagat aatcttacgc ctgaacaaaa agaattgtta gaactacgta aaagaaacca
       61 gcaattagaa atggaaaatg atattttaaa gcaagcagcg ctgatattcg gacgaagaga
      121 caagtaatcg atgcgaataa gcatctttac cctatatcag cgatgtgcag aatattaggt
      181 ctatcacgtc agtcctatta ttatcaatca aaaccaaaga aagacgaatc agaacttgaa
      241 gaagtagtcg ctgaagaatt tatccgcagc cgaaaggcct acggctcaag aaaaataaaa
      301 aaagccttat caaaacgagg cattcagatc agccgacgaa aaattagtag aatcatgaaa
      361 aatagaggat taaaatcgag ctatactgtt gcttatttta aagtac
//
LOCUS       DAZULR010000177          376 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.190, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000177 DAZULR010000000
VERSION     DAZULR010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..376
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.190"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>376
                     /locus_tag="ACG8ZV_002903"
     CDS             <1..>376
                     /locus_tag="ACG8ZV_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HFS4998131.1"
                     /translation="ITQTQLKPEDYPKIFPNRVFDFQLDKKGQSELQAGIQAVANNIG
                     IQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNTRNTPTQHLATSIHELAHARM
                     HKFSELDTATKELQAEMTSYIVC"
BASE COUNT          140 a           69 c           74 g           93 t
ORIGIN      
        1 atcacacaaa cacagttaaa acctgaagac tatccgaaaa tctttccgaa ccgtgtcttt
       61 gattttcaat tggataaaaa aggacagtca gaacttcaag ctgggattca agcggtagcc
      121 aacaatattg gaatacaaat tcgagatatg acagaaagtg aagtctatca aagagaatta
      181 ggacaagcac gtggggcgta tgttcgtaac gaatttactg gcgaagaaga aatcgtcatg
      241 aatactcgaa atactcctac gcagcattta gctacaagta ttcatgaatt agcccatgca
      301 agaatgcaca aattttcaga attagatacc gcaactaaag aattgcaggc agaaatgact
      361 tcttatattg tgtgca
//
LOCUS       DAZULR010000178          349 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.191, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000178 DAZULR010000000
VERSION     DAZULR010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..349
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.191"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(44..>349)
                     /locus_tag="ACG8ZV_002904"
     CDS             complement(44..>349)
                     /locus_tag="ACG8ZV_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFS4998132.1"
                     /translation="TIHEILNGFGITRSLSRKGCPYDNAVVESTYKSVKVEFVHQYQF
                     ETLAQLRLELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSDTSGEAA"
BASE COUNT           98 a           86 c           64 g          101 t
ORIGIN      
        1 atcctcggat ctgattttct ccggcagaag cacaatcatt caattacgct gcctctccag
       61 aggtatcaga tccgcgctca ttatcaagga ttcgcttcgc caatctctgt tgtcgaattt
      121 ggatcggtgt ttcatacgcc aacgtgccat gtaagcgtag atagttccac caatgcacat
      181 aatcaaacaa ttctagacgt agctgtgcca gtgtctcaaa ttggtattga tgcacgaatt
      241 ctactttgac agatttatag gttgattcca caacggcatt atcatacgga caacccttcc
      301 tactcaatga acgagtaatt ccaaaaccat tcagaatctc atgaatggt
//
LOCUS       DAZULR010000179          343 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.192, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000179 DAZULR010000000
VERSION     DAZULR010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..343
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.192"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>343
                     /locus_tag="ACG8ZV_002905"
     CDS             <1..>343
                     /locus_tag="ACG8ZV_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS6-like element ISS1N family transposase"
                     /protein_id="HFS4998133.1"
                     /translation="WLRKKRDTQAAYAFLKRLHKQFGEPKAIVTDKAPSLGSAFRKLQ
                     SVGLYTKTEHRTVKYLNNLIEQDHRPIKRRNKFYQSLRTASSTIKGMETIRGIYKKNR
                     RNGTLFGFSVST"
BASE COUNT          115 a           72 c           70 g           86 t
ORIGIN      
        1 ctggttacga aagaaacggg atacgcaagc agcctatgct ttcttaaaac gactccataa
       61 acagtttggt gagccgaaag caattgtgac cgataaagca ccttctcttg gctccgcctt
      121 tagaaagtta cagagtgtgg gtttatatac taagacagag caccgaactg tgaagtatct
      181 taacaattta atagaacaag accatcgacc tattaaacga cgaaataaat tttatcaaag
      241 tctccgtaca gcctcttcca cgattaaggg catggagacc attcgaggaa tatataaaaa
      301 gaaccgaaga aatggaacgc tcttcggctt ttcggtgtct act
//
LOCUS       DAZULR010000180          340 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.193, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000180 DAZULR010000000
VERSION     DAZULR010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..340
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.193"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            42..164
                     /locus_tag="ACG8ZV_002906"
     CDS             42..164
                     /locus_tag="ACG8ZV_002906"
                     /inference="COORDINATES: protein motif:HMM:NF024811.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998134.1"
                     /translation="MHKPFPDPIQKAIDELGIKNKKRFILVIHYMTCKVRKLVG"
     gene            137..268
                     /locus_tag="ACG8ZV_002907"
     CDS             137..268
                     /locus_tag="ACG8ZV_002907"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998135.1"
                     /translation="MQSAKACGIAFGLAKWGAKNIENFQSVDIIIDSPQEILDLLEK"
BASE COUNT          122 a           46 c           64 g          108 t
ORIGIN      
        1 atctatattt tgatatacaa attacagctt cagatactaa gttgcataaa ccttttccgg
       61 accccataca aaaggcaatt gatgaattgg gcataaaaaa taagaaacga tttatattgg
      121 tgattcatta tatgacatgc aaagtgcgaa agcttgtggg atagcatttg gtttagctaa
      181 atggggagcc aaaaatatag aaaattttca aagtgtagat ataattattg attctcctca
      241 agaaatactt gatttgttag aaaaatagac aaagagcgtg agataaggat agggtctcac
      301 gctctttgtt tttcgccatt taaagattga aatttttgcc
//
LOCUS       DAZULR010000181          308 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.194, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000181 DAZULR010000000
VERSION     DAZULR010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..308
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.194"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..287
                     /locus_tag="ACG8ZV_002908"
     CDS             <1..287
                     /locus_tag="ACG8ZV_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFS4998136.1"
                     /translation="NYPKVTQSLIENQDLLTFYDFPPSIRRTIYSTNLIESFNKQIKR
                     YSRRKEQFQNEESLERFLVSIFDTYNQKFLNRSHKGFQQVTDTLVSMFTE"
BASE COUNT          118 a           58 c           43 g           89 t
ORIGIN      
        1 aaaactatcc taaagtgacg cagtcactca tagaaaacca agacttatta actttttatg
       61 attttccacc tagcattcgt agaaccattt actcaaccaa tctaatcgag tctttcaata
      121 agcaaattaa aagatacagc cgtagaaaag agcagtttca aaatgaagaa tcactagaac
      181 gctttctagt cagcattttt gatacataca atcaaaaatt tctaaacaga agccataaag
      241 gttttcaaca ggtaaccgat acattagttt caatgtttac tgagtaacta attattttgc
      301 aggaggac
//
LOCUS       DAZULR010000182          303 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.195, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000182 DAZULR010000000
VERSION     DAZULR010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 303)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 303)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..303
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.195"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="ACG8ZV_002909"
     CDS             complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="ACG8ZV_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HFS4998137.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLW"
BASE COUNT           95 a           45 c           50 g          113 t
ORIGIN      
        1 ttccaaagaa attgtttgac tcttggaaag tcacgtttta tcaatcttga gctggcactt
       61 ttataggcat tgatgaattt tgtcaattct gttttaggtt gagctttgaa cataatatga
      121 acgtggtctt tatcatgatt ccactccact aaagtaatgt gatacgattc tgaaattctt
      181 tcaaaagtag ttttggcata atcagatatt tcatcatcaa tcacttgtct acgatatttc
      241 gttactaaaa caaggtggta ataaagaaga aatactgaat gattatttgt atctaattcc
      301 atg
//
LOCUS       DAZULR010000183          294 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.196, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000183 DAZULR010000000
VERSION     DAZULR010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..294
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.196"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..216
                     /locus_tag="ACG8ZV_002910"
     CDS             <1..216
                     /locus_tag="ACG8ZV_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998138.1"
                     /translation="VVQILVDKEVISEKVAEALLIPRYWTIETPLVEDAPTMLFEDLV
                     KIAGYELHYQENMETYENEYWLTKLEN"
BASE COUNT          116 a           43 c           59 g           76 t
ORIGIN      
        1 gtcgttcaaa ttttggtgga caaagaagtc atttctgaaa aagtagcaga agctttactt
       61 attccgcggt actggacgat agaaacccct ttagtagagg atgcaccgac tatgctattt
      121 gaagacctag tgaagattgc aggatatgaa ctgcattatc aagaaaacat ggaaacttat
      181 gaaaacgaat attggttaac caaattagag aactaaaaag gagaaaaaaa tatggctcaa
      241 aattactatg acgaatttgt caaattacct ttggataaaa tggcacaaaa aatg
//
LOCUS       DAZULR010000184          279 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.denovo.197, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000184 DAZULR010000000
VERSION     DAZULR010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..279
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.denovo.197"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..>279)
                     /locus_tag="ACG8ZV_002911"
     CDS             complement(<1..>279)
                     /locus_tag="ACG8ZV_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFS4998139.1"
                     /translation="HKSAVITLVECLSKVIITLKPTGRRAEDIENRLNDWFKSMPKHL
                     FKSMTFDCGKEFSNWRSISNSNDIAIFFADPGTPSQRGLNEHSNGLLRR"
BASE COUNT           77 a           57 c           55 g           90 t
ORIGIN      
        1 cgtctaagca agccgtttga gtgctcattt agccctcttt gcgaaggtgt tcctggatct
       61 gcgaaaaaga tggcaatatc gttcgagtta cttatagatc gccagttgga aaattctttt
      121 ccacaatcaa atgtcatgga tttaaacaag tgtttaggca tggatttgaa ccaatcattt
      181 aacctgtttt cgatatcttc ggctcgtctg cctgtcggtt tcaaagtaat aataaccttg
      241 gataaacact caaccaatgt aataacagcg ctcttgtgt
//
LOCUS       DAZULR010000185        20943 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.guided.042, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000185 DAZULR010000000
VERSION     DAZULR010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20943
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.guided.042"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(101..544)
                     /locus_tag="ACG8ZV_002912"
     CDS             complement(101..544)
                     /locus_tag="ACG8ZV_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HFS4998140.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINAMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILTSKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(739..2079)
                     /locus_tag="ACG8ZV_002913"
     CDS             complement(739..2079)
                     /locus_tag="ACG8ZV_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFS4998141.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGIILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHAADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFAAYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLIIFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLTLRKGTLW
                     DKGISFFALAVLWLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            2361..3257
                     /locus_tag="ACG8ZV_002914"
     CDS             2361..3257
                     /locus_tag="ACG8ZV_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HFS4998142.1"
                     /translation="MNKNDVLLIAKNKSLYFFPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMDFSSSEPKTDLFFGATNNGRKERAEKYKQEFTKR
                     GVTTNYFILPLRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYQFYHSENIFLLQERDLDELPEFLHTPFQPIPSELLEFFDAENWAKR
                     FFTTDSAIYEQYEYDLSSVKNK"
     gene            complement(3400..4341)
                     /locus_tag="ACG8ZV_002915"
     CDS             complement(3400..4341)
                     /locus_tag="ACG8ZV_002915"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HFS4998143.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVVLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNKHVDLIVALTKANQLDDMFRSIQSIITENTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEAKLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAEGM
                     VRTIVSEFASIAAKEGITLDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAVWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            4467..5588
                     /locus_tag="ACG8ZV_002916"
     CDS             4467..5588
                     /locus_tag="ACG8ZV_002916"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFS4998144.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALGGTWRTIDGMDLLFRQRKISYLLTNWQGKNTAVIESAQVLGLDLLDKP
                     TDQTIRLASSYALGELIKDTLLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTRKLHLDRRNVLVSKVKVIIAADVTNPYTGQQGAAWQFGRQKGGTDTTLAFLD
                     KQAEKIAQQIKDVWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFELVSQITGLEKQI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDRELEGLFDFLPIV
                     LSIQLGPIDLEEAMEHRQTLEKTEILGQTLSRFFNILPK"
     gene            5846..7348
                     /gene="eat(A)"
                     /locus_tag="ACG8ZV_002917"
     CDS             5846..7348
                     /gene="eat(A)"
                     /locus_tag="ACG8ZV_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection-like protein
                     Eat(A)"
                     /protein_id="HFS4998145.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQAFVYFPQQTKDKERLTYYVLNEIMDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEIAKNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKKVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDALTMNSQVSHHKRLLSVENLQLGYENLLFEPVHF
                     TIEPHQRMAISGPNGAGKSSIIHYLLGTFNGKVVGEKSQPKHLTISYVRQNYEDNRGT
                     LAEFAKKNRVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYI
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLEKI"
     gene            7415..7942
                     /locus_tag="ACG8ZV_002918"
     CDS             7415..7942
                     /locus_tag="ACG8ZV_002918"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFS4998146.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQALAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVVDRLNLPMTADERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECMEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELISYE"
     gene            8154..9215
                     /locus_tag="ACG8ZV_002919"
     CDS             8154..9215
                     /locus_tag="ACG8ZV_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HFS4998147.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQNRLIELGSEAKKNKLELMVDISGEALKRAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPNDIDELKEAAADFSQIEAWHNYYPRLETGLDKEWYQEK
                     NQWLKTQGFLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSEHVQEQFASFQKEQTVLLHTEPVDEVFYEYILGKHTNRQDDARDVIRSADARF
                     REIPPIPVRNTAKRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            9218..10114
                     /gene="murQ"
                     /locus_tag="ACG8ZV_002920"
     CDS             9218..10114
                     /gene="murQ"
                     /locus_tag="ACG8ZV_002920"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016835 - carbon-oxygen lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA];
                     GO_process: GO:0046348 - amino sugar catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HFS4998148.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELPSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISEHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEAAQAKLAEANGFVKGTL"
     gene            10128..12110
                     /locus_tag="ACG8ZV_002921"
     CDS             10128..12110
                     /locus_tag="ACG8ZV_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose PTS transporter subunit IIA"
                     /protein_id="HFS4998149.1"
                     /translation="MAKNELTLEELAKQIYQGAGGMGNVESIVHCMTRVRMKVINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQEMVDLAGVKLGEKLPSASATTAS
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAGTWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALATGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKAVPQASA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVISSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAADK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(12180..12626)
                     /gene="nrdI"
                     /locus_tag="ACG8ZV_002922"
     CDS             complement(12180..12626)
                     /gene="nrdI"
                     /locus_tag="ACG8ZV_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HFS4998150.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEYEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQRFGFPFLADYELRGTPSDVTRVYQILAEKNK"
     gene            12837..14261
                     /locus_tag="ACG8ZV_002923"
     CDS             12837..14261
                     /locus_tag="ACG8ZV_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="basic amino acid/polyamine antiporter"
                     /protein_id="HFS4998151.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNVASIVMSTIFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFINNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGFLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(14438..15211)
                     /locus_tag="ACG8ZV_002924"
     CDS             complement(14438..15211)
                     /locus_tag="ACG8ZV_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFS4998152.1"
                     /translation="MTLLIKQELFKLIKKKSTAVLSVLLVALLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMESQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSIYLYLLAIIVTVLMKLILFPSISFTEKISTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIALFLALGYLVFKRKNV"
     gene            complement(15208..16113)
                     /locus_tag="ACG8ZV_002925"
     CDS             complement(15208..16113)
                     /locus_tag="ACG8ZV_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFS4998153.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSEGTIRIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVKQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDQAARTILTDAGYPLEDPDKIKLLKKNEELLGTVIQLLSAENVHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(16274..16594)
                     /locus_tag="ACG8ZV_002926"
     CDS             complement(16274..16594)
                     /locus_tag="ACG8ZV_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HFS4998154.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGLLLISIIGIKI
                     TSGH"
     gene            17067..17753
                     /locus_tag="ACG8ZV_002927"
     CDS             17067..17753
                     /locus_tag="ACG8ZV_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HFS4998155.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            17755..18699
                     /locus_tag="ACG8ZV_002928"
     CDS             17755..18699
                     /locus_tag="ACG8ZV_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HFS4998156.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            18898..19542
                     /gene="pcp"
                     /locus_tag="ACG8ZV_002929"
     CDS             18898..19542
                     /gene="pcp"
                     /locus_tag="ACG8ZV_002929"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HFS4998157.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            19621..20898
                     /locus_tag="ACG8ZV_002930"
     CDS             19621..20898
                     /locus_tag="ACG8ZV_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998158.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
BASE COUNT         6757 a         3774 c         4370 g         6042 t
ORIGIN      
        1 cacaacctct gattcacggt gttccagaag tagcttcttc ttatttcttg aagttgatca
       61 cttctggaac atcctctttt tttatttgga tggataatgg tcattccatt tctttgatca
      121 tttttttcat tttgtcgatt tcttcttctt gtgcctgaat gatttcttcc gctaattttt
      181 ttacttcagg atcttttaaa tcagctcgtt tacttgtcaa gatagcaata gagtgatgag
      241 ggatcatcgc cttcatccac gccgtatcgt tgacagttgt ttggcttcgt accataaata
      301 aggaaccggc aaaaacaaga agactagcgg ctaaaatcat agcatttatc tttttgtttt
      361 catacatttt ccacatgaac aacaacatga tgactgccat gactgcaccc atcatcaacg
      421 ccatgaatac acgtgtgcga ctgaagaaga tatgatcaag cgcataaaca ttcaaataca
      481 tcataccaaa catgactacc gtcgaaacac caatcatcaa caaaaacttc caatactttt
      541 tcatttaaaa caaactcctt tttcttcatt cctttcttct atcatgtcat gagcgtggag
      601 aacaatcaat taatctgcac agatggtttt tgaacaccgt ttattcggaa aaaagaactg
      661 caacaatttt tgtcgcagct cctttttttc aatagctcca gatattcaat ataaatagaa
      721 taaaattctc tattggtttc attcattcgt caagacgaaa gcatcattct ttttttgata
      781 actgaaataa atgaacaggt aaagcaaacc ggtcaataca gttaccccaa tggagttcgt
      841 gaataggata ccaaggaaaa tcaaccataa gactgctaat gcaaaaaagc tgattccttt
      901 gtcccataac gttcctttcc ttagtgtcag tacaaaggac gcagcactga taatgatcca
      961 gatcaataat actgtatagg aaagagaacc tgccagatag ccaaataatt tgtcaccgac
     1021 aaaataagaa agagccacac ctagataaag aacactggta caaaacagca cagcacgttg
     1081 cggtacttga tgcttgttta aaacagctag ttttctagag gaacctttcc gatctttcaa
     1141 gcggaagaac aaaattctcg aagaagcata tacacctgaa ttgatagacg agaacagagc
     1201 aagaacaatc acgaaattga cgatatctgc cgcaaatgga atattcattt tttcaaatac
     1261 catcacaaaa ggactaacgt tcgtgcctgc taaagtattc caaggaaaaa taatcaaaag
     1321 caaaaataaa ggaataatgt aaaaggaaat gattcttccc atgacgcctt tgattgcttt
     1381 aggaatcgca cgtttaggat catctgcttc gcttactgtg atagcaatca actcagaacc
     1441 gccgtaagaa tagataacta caagcaaaga actgatgatt cccttcatac cgtggggagt
     1501 aaaaccacca tgatcagtta attgttgaag ggtagggaaa acaccagtac ccaacatttg
     1561 ctgaccgaca agataagcag caaaaatgat caataggata atgacactga ttttagcaaa
     1621 ggccagccaa tattctgtct ctgcgaataa tcgtaccgaa taaagattga tgatagtagt
     1681 taaaacagcc aacataaaaa caaataccca agctgggatg tgggggaacc acaactgtaa
     1741 aaaggaagca gctgcaacag cttcagcaat gatattgata atccacatgg accagtagac
     1801 ccaatcggta aaatcggcag catgagcacc tagatatgga cgaatcaatc cagataatcc
     1861 gtggtgcgta tcaccaccac ttaaaacaat ttttcccaga cctttcatca cgatatataa
     1921 aattatgccg ccaatcaaaa aagcgatcaa tacagaaggg ccggcgattc caatcgcttc
     1981 gccacttcct ttaaatagac ctgcaccaat cgctccacct aaagctagca tggtgatatg
     2041 tcgggagcta agttgttttt tcaatttttt atcttccata aataacctct ttcttttaaa
     2101 ttcacaatca aaatgcatag taagaataaa tagtaagaat aaatagtaat aataataatg
     2161 actaatgata acaaattttc agataattac aactattcag aaaacttttg ggcatatttt
     2221 aatggaagaa tgatttattt catcgtattt tcatagaaat gttaaatttt tataaaaata
     2281 ataggaagcg ttttactggc tttttactat ttaaacaggc tatcatagga aaaagtgaca
     2341 gagaaagtga ggcggaacag atgaacaaaa acgacgtatt gctaattgcg aaaaataaat
     2401 cactttattt ttttccttcc atccgctctt tagatgtttg gtccggaaaa gatttactac
     2461 agtcggaatt cattaaatca gctcgacaac agttggcaaa ttatcagctg atcgtttttt
     2521 tagattatgg atttgatatg gagatggctc gacgcgtgcg tccatttacc aatgcaaaaa
     2581 tcgtgttatt tttttggaac cactttaaag cagaacacga ggcgatgctg aagcaggcac
     2641 aagatgaacc ggcaatcgat gagatttatc attttgattt tttagaagcg aaagaacttg
     2701 gactaaaaca taatagttcc ttttattcga aacatatgga tttttcttct agcgaaccaa
     2761 agacggatct attttttggt gcaacaaata acggcagaaa agaacgggca gaaaaatata
     2821 agcaggaatt tacaaaaaga ggtgttacga ccaattactt tattcttccg cttcgaggaa
     2881 atgaacaacc tggatacctt acttatgaag aatatctgaa aaaaaccggg gaatcgaggg
     2941 ggattctaga actgttgcgg gaagggcagc aaggagtgac tttgcgaacg tttgaatcta
     3001 tgtattttca aaagaaacta gtgacagata atcaagccat agctcattat cagttttatc
     3061 attctgaaaa tatttttttg cttcaagaac gtgatttaga tgaattaccg gaatttttgc
     3121 atacgccatt tcaaccaatc ccatcagaac tgttggaatt ttttgatgca gaaaattggg
     3181 caaaacgttt tttcactact gactccgcta tttatgaaca atatgaatac gatctttcct
     3241 ctgttaaaaa taaataaaag tgccaaccaa tcatagatga aaataaacaa gcgcaattct
     3301 tatggcaaca tgagaattgt gtttttcttt ttgaactttc atgggggtaa aaaaatgaga
     3361 accagctgct gatccagctg attctcatca gagagccttt tattctgcgc caaggattcc
     3421 ttcttttgca tggactaatt gggtcaaaaa ggcacaatat ggtgtagcaa tatcatattt
     3481 ttgtcctttt cgccaaacgg caccattgat gtagtcgatt tcagtcaaac gatggttttt
     3541 gatcaggtct tggtacatag atgggtaatg caacccgatg ttgtcaggat cataagtaga
     3601 agcaatatgt tggtacactt cttcttgatc taatgtgatt ccttcttttg ctgcgataga
     3661 agcaaactca gatacaatcg ttcgaaccat gccctctgcc gctttttgcg cacctaattc
     3721 agcaatatta caatccaata tcgtgcataa tccatttaat gttccgttta cacaagcttt
     3781 tcgccaaatg gaataacgaa cattatgact atagattgga ttcaattttg cttcttgaaa
     3841 gacttctaca actttttttg taaatgcttc gccttctggt tccaagttct ctagttcgat
     3901 ttctccatca cctaataatg tgacttttcc gggaccagct agaccagctg tccacatcgt
     3961 gatcccaaat aagatatttt tctttggtac atatttttcc agtacatctt catgacctaa
     4021 tccattcagt aaacacaaaa cataagtatt ctcagtaata atggattgga tcgaacgaaa
     4081 catatcatct aattgattcg cttttgtcaa ggctacgatc aaatccacgt gtttgttgct
     4141 ttcgatgatt tcttctggtg aatagattgg cagttttgca actacttctt tgccattaaa
     4201 gtcagcaatc aatccatttg tacgaatggc ttcaatgtga gcaggccagc gatcgatcaa
     4261 gacgacctca tttccgcttt gatgcaacat taatccgatt cggctgccca ttgctccggc
     4321 tccagctatt gcgattttca tgttttttct ctcctttatt caatgagttc ccttttagta
     4381 tatagaaaaa cagaagaaaa tagcattgtt ttgtttgaaa aaagtgaaaa aaagtgtctt
     4441 acttaagaag aaagtgaggg atatagatgg atattttggc ggcaatcgat tcatttaaag
     4501 gaagtgcttc ttcatttgaa ttaaatcagg cagttctaaa tggttgggaa gaccgtaaag
     4561 gaagaaaaat caatgtgccg attgcagatg gcggagaaaa tactgcagaa gcaatctatt
     4621 acgcgctcgg gggaacctgg cgtacgattg atgggatgga tctcttattt cgtcagcgaa
     4681 aaatcagtta tttattgacg aactggcaag gaaaaaatac cgcagtcatt gaatctgcac
     4741 aagtattagg attagattta cttgataaac caacggatca aaccatccga cttgcttcta
     4801 gttatgcctt gggagagctt atcaaagata cactgcttca agaagtggaa caaatcattg
     4861 tcactttagg aggaagcgga tgtagcgatg gtggtctagg attactccaa tctttgggtg
     4921 cttctttaga agggtacaca gaaggaaatc ctttgttatc tactagaaaa cttcatttgg
     4981 atcgaaggaa cgttcttgtt tctaaagtaa aagtgatcat cgctgcagac gtgaccaacc
     5041 catatacagg tcaacaagga gctgcttggc aatttggaag acaaaaagga ggaacggata
     5101 cgacgttagc tttcttggat aaacaagctg aaaagattgc tcagcagata aaagatgttt
     5161 gggaggtgga tttagatgac atcccaggaa gcggagcagc aggcggtatt ggcggagccc
     5221 tttttttgtt aggagcgaag atggtctctg gttttgagtt ggtcagccaa atcactggat
     5281 tagaaaaaca gatcgaacaa gcggatgtca tcattacagg agaagggcgg attgatcagc
     5341 aaacaatcca cggaaaagtt ccatatggcg tagcagtgct tgcaaaaaaa tatcgaaaac
     5401 caataatcgc tatttgcgga agtagagacc gagagctgga aggactcttt gattttctcc
     5461 ccattgtctt aagcattcaa ttaggaccaa tcgatttaga ggaagcaatg gaacacaggc
     5521 aaacattaga aaaaacagaa atcttaggac agacactcag cagatttttc aacattctcc
     5581 cgaagtagtt gacaaaaaca atttctttat gctatcgtaa tttcaaatat aggacaaagt
     5641 gagggatccg tgcattgaaa aattaagtcg attgatgaaa gctgcattca gactgtacct
     5701 tgtggagaca agggagcagt gtgcagattt tcgggattgg cttggttctt tcgatgtatg
     5761 ggtctttttg tgtgccccaa cccttgcatc ctctttagcc agttctgaaa ataggactgg
     5821 tcttttttta cgaggtgatg gaataatgtc taaaatcgaa ataaaaaatc tgacattcgg
     5881 ctatgacagc caaggcacat tattatttga acaagccaat ctaaactttg acacacaatg
     5941 gaaactagga cttatcggac gaaacggtcg aggaaagaca actttactga atatcctgca
     6001 aaacaaactc ccttatcaag ggcaagtgat ccatcagcaa gcgtttgtct atttcccgca
     6061 gcaaacaaaa gataaagagc gtttgaccta ttatgtgtta aatgagatta tggattttga
     6121 gatatgggaa attgaaagag agctccaact gatgcaaaca gatcctgaaa tcttatggag
     6181 agaattcagc acactatcag gaggagagaa gacaaaagtc ctactggcac tcttatttgt
     6241 ggatgacact catttcccgt taatcgatga accaacgaat catttggata tctctggcag
     6301 aaaacaagta gcggcttact tgaaaaagaa aaaacaagga ttcatcgtgg tgagtcatga
     6361 tcggggattt atcgatgaag tagtggacca tgttttagca atcgaaaaga gccaactgga
     6421 actttatcaa gggaatttct ctatctatga agaacagaaa aaacttcgtg atgaatttga
     6481 aatagctaaa aatgaaaaat tgaaaaaaga agtcagcagg ctaaagaaaa cagcagctga
     6541 aaaagcagaa tggtctcgtt cccgagaagg ggacaaaaca aagaaaaaag tcggattcat
     6601 cgatacggaa tctaggcgag tgaataaagg agcagtaggc gctgatgctg cacggacgat
     6661 gaaacgatct aaagcaatcg tgaatcggat ggaaacccag atcagtgaga aagaaaaatt
     6721 attaaaagat atcgagtata tcgatgcttt gacgatgaat agccaagtgt ctcatcataa
     6781 acggctgtta agcgtagaaa atcttcaatt agggtatgaa aatctgttat tcgagccagt
     6841 tcattttacg atcgaacctc atcagcggat ggcaatttca ggtcctaacg gcgcgggaaa
     6901 gtcatccatt atccattatc ttctggggac attcaacggc aaggttgtag gagaaaaatc
     6961 ccagcccaaa catttgacca ttagttacgt acgccaaaat tatgaagaca atcgagggac
     7021 attggcggaa ttcgcgaaga aaaaccgagt agactatcaa gcatttttga ataatctccg
     7081 aaagcttggg atggaaagag atgtttttca taataaaatc gaacagatga gtatgggaca
     7141 acggaaaaaa gtggaattgg ctaaatcttt atcccaacca gctgagctct atatatggga
     7201 tgaaccattg aattatttgg atgtcttcaa tcaagaacaa ttagaacaac tgattttgaa
     7261 cgtgaaacct gctatgttac tagtggaaca tgatcaaacc tttctagata aagtatctac
     7321 tgagattatt tctcttgaga aaatctaaac cttgtaatct caaagacaac aaggtatggt
     7381 taaggagaac tttgtcaacg aaggagagaa tcacatgctt tatgtaacga gacacggaga
     7441 aacaacttgg aacgcacaag gattagtttg cgggcgagca gatgtgccgc tgactgaaaa
     7501 aggacagatg caggcacagg cactagcaga aaaggtagta gatttgcctg ttccaatcac
     7561 gaaaatcatc cattcccctc ttcaacgagc aagagataca gcacaagcag tagttgatcg
     7621 tctcaatttg ccgatgaccg ctgatgagcg attggtagaa atggattttg gggattatga
     7681 cggactgcca agcaaagatg aaaactttca aaaagcgcgt ttagcgtttg ctgtacgttt
     7741 cccaaatgga gagtcggtct tagatgtgta cgcacggatc gttcctttat tgaaagaatg
     7801 catggaagac gaagaaaatg tctacttgtt agtctgtcat aatgccttga taagagtgat
     7861 caatgcttat tttcatccaa tgcctaatga agggttcttt acattcatgg tagacaatac
     7921 agaattaatt tcttatgagt aattagactt ttgtgttatt taaataaaat gtttcaaggc
     7981 actgcttttg cttagcagtg ccttttttgt ggctgtgtca attcttttgg cattataaat
     8041 ccaattttta gaaataaaat ttaattattt taacaaaagt attgaaattt tgtttcttta
     8101 gatatatact ctagtcatag aaatgaagac ggatacagaa aaagagggat aatatgtttg
     8161 gcttttcaat atttatgaat gattctttgt cagaagagaa gaaacagtat atccgccaaa
     8221 tggcatccaa tggctttgtc ggtattttca cttccatgca tataccggaa gatgatgttt
     8281 cggcttatca aaatcgattg atcgaactag gaagcgaagc gaaaaagaat aaactagagt
     8341 tgatggtcga tatttcagga gaggcattga aacgagctgg cttttcatta gaagatctaa
     8401 cacccttgaa agcaattggt gtaacagggt taagaatgga ttatcatatt tctaatcagc
     8461 agatcgccga ctggtcacat caattgaaaa tcagtttgaa tgccagcacg atcacgccta
     8521 atgatatcga tgagttgaaa gaagcagcgg ctgatttctc acagattgaa gcttggcata
     8581 attattatcc acgtcttgaa acagggttgg acaaagaatg gtatcaggaa aaaaatcaat
     8641 ggctcaaaac tcaaggattc cttgtacaag gctttgtacc aggagataca gagttgagag
     8701 gtccactgta tcaaggatta ccaactttgg aagaacatcg agggatccat cctctggcag
     8761 gtgctcttga tctattagca agtaacacgg atattgttta tatcggagat gcaggtctgt
     8821 cagaacacgt tcaggagcaa tttgcttctt tccaaaaaga acagacagtc ttgctccata
     8881 cggaacctgt agatgaagtt ttttacgaat atatattagg aaaacatacg aatcggcaag
     8941 atgatgcaag agatgtcata cgaagcgcag atgcgcgttt tcgagagatt ccgccaatcc
     9001 cagtaagaaa tacagctaag cgtatgaaag gatctattac tttagataac gaaaagtatt
     9061 tgcgctatat gggtgagatc caattaacta aatatgattt gccagcggat gaaaaagtga
     9121 atgtagtagc caaagtcatc aaagaagaac taccgctgat caaccaaatc aaagctggta
     9181 tgaactatca atttataaga aaagaaggaa gataaaaatg agcaaaatca atttagagaa
     9241 cctaacaacg gaacgcagaa accaagaaac ttttggatta gatgaaatga gtatttctca
     9301 agcagtccaa ctcatgaaca aagaagatca gaaagtggcc gctgctgttg aaaaagaact
     9361 gccaagtatc gagccagtga tcgccaacac gattgaatcc tttaaaaaag gtggtcgctt
     9421 gatttatatg ggagctggaa cgagtggtag acttggtgta ttagatgctg ctgaatgtgt
     9481 accgacattc ggtgtagaac cggaaatggt cataggccta attgctggtg gagaagaagc
     9541 aatgactgta gccgtcgaag gagccgaaga ttcttatgaa ttagggcaag aagatctaat
     9601 caagctgaat ttaacaaaaa atgatatagt tattggtatc gcagctagcg gtcgtacacc
     9661 atatgtgatt ggtggattag attacgcaaa atcgattggt gctgttacag gaacgatttc
     9721 ttgcaataaa caagcagaaa tcagcgagca tgcggatttc ccaatcgaag tcgatgcagg
     9781 accagaattt ttgacaggct ctactcgatt gaagtcagga acagcacaaa aactgatttt
     9841 gaatatgatt tctactatca gtatgatcgg tatcggtaaa gtattcaata acttgatggt
     9901 cgacgtcaaa ccaacaaatg aaaaactaat tgaacgctca aaacgaatca tcatgcaagc
     9961 gacagaagct gactacgaaa cagctgaaaa gtactttgag gaagcagatc aaaatgtcaa
    10021 actggctatc gtcatgattt tgacaaatag tgataaagag gcagctcaag caaaattagc
    10081 tgaagcaaac ggttttgtaa aaggaacctt atgaggggga aaagaccatg gcaaaaaacg
    10141 aattgacttt ggaagaactg gcaaaacaaa tttatcaagg agcaggcggt atgggcaatg
    10201 ttgaaagcat tgtccactgc atgactcgtg tacgtatgaa ggtcatcaat gatgatcttg
    10261 taaatgtctc ggaattaaaa gcgattccag gagtacttgg cgtagtagag gatgaacagc
    10321 tccaagtcat catcggacct gggaaagtga acaaagtagc gcaggaaatg gttgacttag
    10381 caggcgtgaa attaggagaa aaacttcctt ctgctagtgc aactacagca agttcttctg
    10441 catctggaaa agaccgtgta aacgaacggg cacaagaaat gaaagcggca caaaaatcga
    10501 aacaaaaacc ctctaaaatc aaatcggtat taaaagacat ctctaatatc tttgtaccaa
    10561 tgatccctgc atttgtcggc actgggatcg tggcagggat tgccgcagtt ttagcaaact
    10621 tagtcacagc tggaacacta gacgcaggaa catggcaaca atatatcgat gtgatgaaca
    10681 tcttgaaaaa cgggatgttt agctatctag ttatctatac aggtatcaat gctgcacaag
    10741 tttttggtgc aacgccaacg cttggtggag ttatcggggc tgttgtgatg ctgacaggga
    10801 tgaatccaga agcaccactg aaaaacttgt ttaccggtga agctcttgca actggacaag
    10861 gcgggatctt aggtgttatc ttcgcagttt ggttattgtc aatcgttgag aaaaaactgc
    10921 ataaagtagt acctgatgcg gtagatatca tcgttacgcc aactctttcc ctgattgcca
    10981 tcggtctgat cgaaattttc ttcatcatgc ctttagcagg gttcatttct gacggcatgg
    11041 tcggtgggat caactgggta cttggtgttg gaggagcatt tgccggcttc gttctaggta
    11101 cattattctt gccaatggtc atgttcggac tacatcagat cttgacgcca atccatgtac
    11161 aaatgattga tgaaactggt cgtaccttat tgcttccaat ccttgcgatg gccggagcag
    11221 gacaagtggg tgcagcattg gcattatgga tccgctgcaa aaaagacaaa gaattaacag
    11281 aaatgatcaa aggggcttta ccagtcggaa tcttaggaat cggcgaacca ttgatttacg
    11341 gagtaacatt acctctagga cgtccattta ttactgcttg tatcggtgga ggtatcggtg
    11401 gggcagtgat cggaatgatc ggaaatgtcg gagcaatcgc tattggacct tcaggagccg
    11461 ctttgattcc attgatctct gatggtaaat ggttaggcta tatccttggt ttattggctg
    11521 cttacgctgg tggcttcgtt gctacattct tcttcggtat tcctaaagac cgtttagaaa
    11581 aagaagaact agcgaccgaa acagccacag taaatgaagt acctgaaaaa gcagtacctc
    11641 aagcttcagc tgaaagtgtg actatcttat catcagttgc tgacggaaca gttgtttctt
    11701 tagataaagc aagtgaccca gtttttgcac aaaaaatgat gggtgaaggt tactttgtag
    11761 aaccagaaaa cggacatatc tattccccgg ttactggagt aataagttct gttttcccaa
    11821 caaaacatgc tatcggcatt acgacaccaa atggcttaga aatcttgctt cacatgggca
    11881 tcaacacagt tgacttaggc ggtacgccat tcgatgtgaa agtaacagaa ggacagcaag
    11941 tgacacctga tacgcttgta gcagaagctg acttagaagc aatcaaagca gcagacaaag
    12001 aaacctccat gatcgtcttg gtaaccaata tggatcgtgt aaaaaacttt gtcttggaaa
    12061 aaacaggtaa agcgaaagca aaagcacctg tgatggatgt caaagcttaa taagaataga
    12121 aacaatagag aacataaaaa gaagaagccg aaatttattt ttcagcttct tcttttgtgt
    12181 tatttatttt tttctgccaa aatttgataa acgcgtgtca catcagatgg tgttccccgt
    12241 aattcataat ctgccaagaa aggaaagccg aatctttgtg cgtattgttt ggctgtcaga
    12301 caatattgat tgttgaagtt tttattaccg ctaccgacta caccaaggca aagtttatga
    12361 ttgtcttcgt attccagata ttcgcgcatc gtttcggtca agatttctgt gtcaccgttg
    12421 tctaacccat tcccgccgtc taaataagta ggaacgaaag taaaaaatgg ttctgtttct
    12481 ttcgtaaaat cactattttc atggatttct tttaaagtaa cttcaggatt gacaggatct
    12541 tctgcatgca ttttttcagc atattctgct agatgtttgg caaaagcacg cgtatttcct
    12601 gaaatcgata tatataaaat gttcatggat catcccccaa ttctttccct ttagtatagc
    12661 atctttttaa gtttttttgg tggtgtaatt tggaaaggga ctaggcgctt tgcttgtata
    12721 atgagaaaaa agtcggtaga attatatttc tattaaagtt tttattaatt aagtaaaaat
    12781 aaaaaaggtt tgttatactt tttgataaaa gcggttttac tttggaggat gcttacatgg
    12841 atacagagca acagaaaaaa ggaattggtt tgattccact tgctgcctta gtgattggtt
    12901 cagcgattgg aggtggcgta tttggtatta tgacggacat ctccggatcg gctggtggcc
    12961 cagctatctt cagctgggta ctcgtaggaa cagcaatgtt gatgctctcc ttatcgatca
    13021 ataatatcaa taaaaaacgt ccagatttaa aaggcgggat ctttagttac gcagaagaag
    13081 gttttggccg tttcgctggt tttatcagcg gttggggtta ctggctcaca tgctggttag
    13141 gaaacgtggc gttcgcaaca ttgttgatga gtgcattagg ttatttcttc cccgtattcg
    13201 aaggtggtca aaatgtggca tcgatcgtga tgagtacgat cttcttatgg ggatatgcat
    13261 ggctagtgaa tcgtggagtt gaaaatgcta gctttgtcaa tgctatcgtc acattttgta
    13321 aattagtgcc attattttta tttattgtag tagctatcag caccttttcg atccaacaat
    13381 tcattaataa cttttctagc gatatcatat tgaatgcgaa tgggcagccg atcccgtttt
    13441 ctagtcaagt attgagttgc atcatggtga tgctctgggt attcgttggt attgaaggag
    13501 cttctgtcgt aggttcacga gcaaaaaaac aatcggatgt tgggaaagca acgattctag
    13561 gaatattcgg tttgatcatt atttacgtct tggtttccat gcttccatat ggcacaatga
    13621 cgatgaatca gctgcaaacg atcaaagcgc aacctgctat gggatatgta tttgaaatga
    13681 tggttggtaa atggggggcg gtcgtgatca acggcggttt gatcatttct ttagttgggg
    13741 tttggctctc atggacaatc ttgccgattg aaacaatggg gaatatggct gaggacggac
    13801 ttttgcctaa agcatgggga aaactcaaca aaaatggggc accaacttat gctatcgtat
    13861 tgacgacgtt atgtacgaat gtctttttac tttcattatt attcactgac agtgcatata
    13921 actttgctta tacacttggt acagcagcga ttttcttcac gtggcttttc ttagggctgt
    13981 accaaatgaa gctttcttat cagcggaaag agtgggtcca atttttagta gggtttttag
    14041 caagtgcttt tcaagtatgg gccatgctag ttgtagcctt taatgaagtg atgcttgttc
    14101 ttgttctttt cttaccaggt atttattttt acctcaaagc acgtaaagaa caaaacgaac
    14161 ctgtacaaca tatccactta gataagattt tacttatcgg tgtgacgatg gtcggagtaa
    14221 tcgcaatggt tttatttgcc actgggatgc ttcacgtata gaagtataaa gagaggctgt
    14281 gaagcctgtg gtttattcaa aaaagaagcg gtgacaacat tcgtgtcatc gcttcttttt
    14341 ttgaataaat ggtgttcaag aagtagcttc ttctaaaaat aagccgaaat ttcttgaaac
    14401 tggccacttc tgtcacaact tctttgttaa tgaaccatca tacatttttt cgcttgaata
    14461 cgaggtatcc caatgctaag aacaaagcaa tgtaagctaa attgccaaac agcatttgat
    14521 tagtagaaag atgagtcaat tgcttcataa tctcttcgtt gccaatttgg ttttgcagat
    14581 tcagcatact gattggattc catttgatcc actcccattt ttgaatgagt gcgatgagga
    14641 taccagatat gattgatgaa gcaaaataaa agacgatccc tgctgagatg gaggcaccgg
    14701 aactattgat aaaacaagca atcatcaaca ctaaacttaa aattagccat aaaccgatat
    14761 aactacccaa agtataagtg aataagcttt ggatcagtgt ctgaccagta gaaatcttct
    14821 ccgtaaagga aatcgaaggg aaaaggatca gtttcatcag cacggtgaca ataatagcta
    14881 aaaggtataa ataaatagaa taaataacta atgtgatcca tttacttact aatatttctc
    14941 ctcgagaata ctttcgataa aggagatttt tcaatgtacc atattgtgat tccattgaaa
    15001 tgatcgtact tgcagcagca atcatgataa agacaatcca agatgtggca ctgaaaagct
    15061 gagcagtcat ttcaactgga tcaatgatcg tcgtgtattt tttggctaga agtgctgttc
    15121 ctatgagcaa agcaactaat agaacagata aaacagcagt tgactttttc ttgatcaatt
    15181 taaataattc ttgttttata agcaacgtca tttttcttct tcccccttta ctgaatccag
    15241 aatttccaat agggaagatt ccaaatcatt cgtcagatgc tggacatctg tcacatggac
    15301 attttctgca gacaataact ggataacagt tcctaataac tcttcgtttt tttttagaag
    15361 cttgatttta tcaggatctt ccaagggata tccagcgtct gtcaagatcg ttcgagcagc
    15421 ttgatcattt gtcgtagaga taacgatgaa atcttgcgct gtttggttca attcagccat
    15481 tgtacattgt ttgatgattt ttccttgatt gatcaggatc agctcatcga ccattttttc
    15541 aagctcgctg agtaagtgac tggagatcaa gaaagaggtg ccctgagtag ccaagtcggt
    15601 aatgattttt cgcacatctc ttgttgcttg tggatccaaa ccgttcatcg gctcatctaa
    15661 aataacgata gacggatggt tcagtaaggc aagagcaatt cccaattttt gtttcattcc
    15721 cagcgagtag gatttcgctt ttttgtgaat gtatttttcc atcttgagct gtttcacgat
    15781 agtgtcgata gcagatacat cgtttgtttc agagaataac ttcagatgat cataacctgt
    15841 taagaatgga tagatacccg gatattcgat caatgctcct acttgttcta atcctttatg
    15901 actagaggga gaaatctcat tttcaccaat acggatcgtt ccttctgagt aatggatcag
    15961 tcctaaaata gctttcatga tcgttgtttt tccagcgcca ttaggaccta ctaatccaac
    16021 gattttgcca ggagataagc taaaactgac atcgctgagg gcttgtttgt gaccaaagtt
    16081 cttggataat tcttggaccg aaagactttt caaaaatatt cactcctttt ctatagatag
    16141 tacaagcata cacctgatga gtagagaagt cgctaggtca ttagtcttat tttcttgttt
    16201 tttcatagaa agaggaatat caaataaaaa gccccgcttt ttctgatcag tccttgtctg
    16261 cttgtctaag tatctagtga ccgctagtga ttttgatgcc aatgatgctg atgagcagca
    16321 acccgacaaa gaaccaagtg gaaagattca gcttatcatg aaacaagacc acaccaataa
    16381 tgaccgaacc aactgcgcca atccctgtcc aaataggata agagagactc ataggcaaac
    16441 ttttgattgc ctttgacaaa aagtaaaaac tagcaatcat tccaatcact gtgtaaaaag
    16501 aataattgat tttagaaaaa ccatcactcc atttcatcat cgttgaccag aatacttcca
    16561 aaattcctgc tatgattaat tccatccatg ccatacatac gttcctcctt caatataaaa
    16621 aatacacaaa aagaggagaa tcatcccttc aaagacctaa tggaatgatc atcctctttt
    16681 ttactacccg gtggcagatc gtatatcttt ttctgtagta tagcacacct atccagatat
    16741 cggcaatctc atacttttta gtaaagtgta acaagcattg acggatatat cgttagcaga
    16801 aaagaagatg aatgctttgc aatttcatag aaaggagttg ttatttatta atcatttaaa
    16861 aaaacagtaa ctagacctta tttttatata ttagcaggca ataaattaaa aaaagcttta
    16921 tcttacaata agtaaggtga attatataat aaaaaaataa cgaaaaatat ttaaaaatag
    16981 tgtctatttc gtgagaaaac aactatattt tttatgtgtt ttgctttata attaaaaaaa
    17041 tattgtcatt ttatggagga aaatatatgg aaaattatct tagcctttta ggcgtcttga
    17101 ttgttattct cgggtttgca tttaaattag actcgatatt gatcgtaatg gttgctttag
    17161 ttgttacagc tttgactggc ggtcttggca ttcaaggaat gttagaactt ttaggtacaa
    17221 gttttgtaaa caatcgcggg atggcgattt ttatcatcat tatgttggca acaggaacgc
    17281 ttgaaagaaa tggtctgaaa gaatcagcgg cttccttgat caagcgattc aagaaagtat
    17341 ctgctggtat gattgtagat atttatggga tctttcgaat gatctttgcg gcttttaacg
    17401 tgagttttgg tggagttgct ggatttgttc gtccaatcat tttaccgatg gcattgggga
    17461 ccatcgaatc aaaagggtta gaagtccatc ctaagcatga agaagaacta aaaggtatgg
    17521 cttcagctat ggaaaatgtc tgctggttct ttggccaagt actattcatc ggaggagcag
    17581 gggcgttgct agtccaatca acactgaaag atctaggata tgacgtaaca ttgggacagc
    17641 ttgctttagt ggaagttcca gtggctatca cggctttagt tgtggcaagt gtctacttct
    17701 atcttaaaga aaagaaatta gcgaagaaat attatccagg aaaggggcaa taagatggac
    17761 ttttttacaa atcctgatat tttattaggc gataaattac tggagatcct ttatatcgtg
    17821 atgggactcg tattgattta cactggagta agaaatttaa cagataaaac caatcctcat
    17881 cgttatgggt cagccttttt ctggacggtc ttaggggtag ttattgcagg aggaagatgg
    17941 cttccggcaa tcgtgaacgg tggcttgatc tttgcgatga ccataccagc aattgctaag
    18001 aaagtcagca aaggagaaag ccggcttcca tcaaaagaat atatggaaaa aatgtcagac
    18061 aaactaggaa tgaaaatttt tattccagct ttgagtatcg gtgtctttgc gatcttgttt
    18121 gctctattta ccaatttagg tgctttagtc ggcgtgggcg tcggtgtttt tgcagccatg
    18181 ctaatcttga tgttcttttc tcgagataat cgaccaagta catttttaga tgatgcagca
    18241 gatatgctgg gcacagtagg gccgttaagc atgttgccaa tgcttttagc ttctctaggt
    18301 gcggtattta caagcgctgg agttgggaca gtgatttcca atgcagtagg tacgatcgtt
    18361 ccagaaggaa atgtgaacat cggcatcatc atttacgctc ttggcatggt gatatttacg
    18421 gtaatcatgg ggaatgcatt tgcggccatc accgtgatga cggttgggat cggtgcacca
    18481 ttcgtattta gtcatggagc gaatccagcg ttaataggaa tggttgcatt gacttgcggt
    18541 ttttgtggga ccctgctgac accgatggct gctaacttca atatcgtgcc tgtagcgatg
    18601 ctggagatga aagacaaata cggagtgatc aaaaaccagt tgtttattgc gttatttatg
    18661 ctagttttcc aaattgctta tatgattcta tttaaataat agaagagagg ggttgtgaca
    18721 gaataattgt cgcaacctct tctaacattg tagtggaaca ctattttttt ataagaatat
    18781 attaagtttg atctgttatg ttatttaaac tattgtttcc tttatttacg ctgttcaagg
    18841 aaaatggtat gataaaagat aaccatatgt taaatcaatc ggacggagga acaacagatg
    18901 aaagtactag taacaggttt tgatccattt ggtggggaca aagtgaatcc agcctatgaa
    18961 gcagtaaaaa aaatgccaga tgaaatcagc ggtgctgaaa tcatcaaagt ggaagtaccg
    19021 accgtattcg aaaaaagcag tcaagtagtc aaagaagcca tccaacagca ccaaccagat
    19081 gtcgtgatct gtgtcggaca agcaggtggg cggtcagcag tctcgttcga acgtgtcgca
    19141 atcaatctag cagaagcaag aatccctgat aatgaaggaa atcagccatt cgatacggct
    19201 ttagaagaaa acggtccagc cgcttacttt acctcattgc caatcaaagc aatgacaaaa
    19261 aatgtacaag atcatggtct accagcgtac atctcttata cagcaggaac atttgtctgc
    19321 aatgatatca tgtatcgttt gcttcatttg atcgaaacac aattcccggc aattcgaggt
    19381 gggttcatcc acgtgccatt ctcacccgat caagtgatcg atcgtccagt gggtacgcct
    19441 tctatgtctt tagaagacat tgcttcttct ttgacttatg cagttgaagc agcagtagaa
    19501 aataaagaag atatttccgg aaatgccgga acaactcact aatttagcaa gaaacactgg
    19561 ctggttgcta acgttatgtt agtagccagc tttttgtaat tagaaaggaa agaaacagcc
    19621 gtggaagaat ggcaatccgt ctttgaagaa tggtttccaa aagaaatcag caaaagctat
    19681 cccatcaaaa tttctaaaca atacacaagc agtcaacgtt gggagatcta tgcaaaatta
    19741 acgaaaaaac agcgggaact agtcgataag caccgccgat atctaatcag ctctcgtttt
    19801 atggaagaac attatttagc tgcaacagat tgggtgtttt ctgacttcaa gatcaatccg
    19861 ttttttcgaa caaaacgaag ccagcaaaaa ttgtattgtg agtgtggtag agaattaaaa
    19921 gtgcaataca tcgttaaatc gccaaaaacc ggaaagatcc taaaactagg catcaaccac
    19981 tttgccgatc acctgcatgt ctctccgaca gtggcagctt cgatccatca gggaatgaca
    20041 aaagttgatc tggccttaga cgaattatta tggcttaagc agaagaatat cgattttcct
    20101 gaaggactat ggcaaaaata ctgttttgtc ttgtaccaaa atcgtcggat gaaacagcca
    20161 tatttaccgg atataaaatt agctcagcgg ctcgcagaat ttcgccaagt agaaatgccg
    20221 atttacatag cggattatca agcattggaa aatgaaatca agaaaataag tgaacacatc
    20281 aatgggcagt caaaaaagcg acagataaaa aaagaactat ttgacgactt tgcagaagaa
    20341 ttagtaaagg atgtagaaga attcttgatc aactatcgcg catttttacg taaagattgg
    20401 caatccatcg tatatgaaga agtgccagta catcctaatg cttattttga aacatttatt
    20461 tccgtgttga gaaagacaaa acgtcaacga acaccagaag tcactgctca gatggaatat
    20521 tttgcgaaaa accaacgatt catccaacca aaaatctatc tatttatttg gaagcaatat
    20581 tgtcgctatg gttttacaga agggttcttc gacagcattc ctcggatagt cagaaatggt
    20641 tttttaaaag tattgcgtaa agaacgagaa gctatacaat ctgctgataa gaaagaccgt
    20701 acagtctcaa aagaaaaatg gcaactagta gtgaaagata tccaatctgg aaatgtgcaa
    20761 gagacaatcg acaaatggaa aggaaaacat tatcgtttta ctgaagctca gaaacaagcg
    20821 ttggaatatt atcagaagtt agaagaatca ctgcgtttca atgatgaggc aagaaagtat
    20881 ctgaaggaat tactataaaa aatagaggct gggacagaag cgtttaactc caagaaataa
    20941 gaa
//
LOCUS       DAZULR010000186        13213 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.guided.064, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000186 DAZULR010000000
VERSION     DAZULR010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13213
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.guided.064"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(204..2162)
                     /gene="nagE"
                     /locus_tag="ACG8ZV_002931"
     CDS             complement(204..2162)
                     /gene="nagE"
                     /locus_tag="ACG8ZV_002931"
                     /EC_number="2.7.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015572 - N-acetylglucosamine
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-specific PTS transporter
                     subunit IIBC"
                     /protein_id="HFS4998159.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(2159..3031)
                     /locus_tag="ACG8ZV_002932"
     CDS             complement(2159..3031)
                     /locus_tag="ACG8ZV_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFS4998160.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(3373..4245)
                     /locus_tag="ACG8ZV_002933"
     CDS             complement(3373..4245)
                     /locus_tag="ACG8ZV_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFS4998161.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            4373..4942
                     /locus_tag="ACG8ZV_002934"
     CDS             4373..4942
                     /locus_tag="ACG8ZV_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DapH/DapD/GlmU-related protein"
                     /protein_id="HFS4998162.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            5009..5746
                     /locus_tag="ACG8ZV_002935"
     CDS             5009..5746
                     /locus_tag="ACG8ZV_002935"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFS4998163.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            5977..7245
                     /locus_tag="ACG8ZV_002936"
     CDS             5977..7245
                     /locus_tag="ACG8ZV_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFS4998164.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            7732..8196
                     /locus_tag="ACG8ZV_002937"
     CDS             7732..8196
                     /locus_tag="ACG8ZV_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFS4998165.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            8180..8809
                     /locus_tag="ACG8ZV_002938"
     CDS             8180..8809
                     /locus_tag="ACG8ZV_002938"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFS4998166.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            9163..10641
                     /gene="msr(C)"
                     /locus_tag="ACG8ZV_002939"
     CDS             9163..10641
                     /gene="msr(C)"
                     /locus_tag="ACG8ZV_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HFS4998167.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            10688..11134
                     /locus_tag="ACG8ZV_002940"
     CDS             10688..11134
                     /locus_tag="ACG8ZV_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HFS4998168.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(11333..11848)
                     /locus_tag="ACG8ZV_002941"
     CDS             complement(11333..11848)
                     /locus_tag="ACG8ZV_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFS4998169.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            11965..13167
                     /locus_tag="ACG8ZV_002942"
     CDS             11965..13167
                     /locus_tag="ACG8ZV_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFS4998170.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         4116 a         2424 c         2708 g         3965 t
ORIGIN      
        1 agaggttgta aaaaagctgt tctgcatcaa gtaataagaa gagtcaaata aaaaatagct
       61 cttcatatgt tacgtttggc tggacttatt accgcggagt tggcaggaga acgccgtttt
      121 tattcggaaa aaggagctga gacaagattt ttgtctcagc tcctgtttgt ttatcgataa
      181 aaaagtctgg ggaagacgat ggctcaggct ttgttggaaa cagagccgat tttatcattt
      241 gcttttacat cacgtgcggg ttcgatttct aagctttgga ctttgtcgcc atttgtgaat
      301 acaacgacca tatccgtgtt tttgcctgca gattgaatag cggcaagatc aactaaagca
      361 atcaattgac ctcttgcgac tttttgacct tcttttacat ataaagtgaa tggttcgcct
      421 tttaagtcaa cagtgttgat gcccatatga agcaagactt cgataccagc atctgtttgg
      481 attccgacag catgtttcgt tgggaaaatg tttgtgatcg taccagcgat tggagagaag
      541 atttctccat tttctggtaa tacagcatag ccgtcaccca tcattttttc cgcgaataca
      601 tcatctgaaa cttcagtgat tggaatcagt ttcccatttg cgatagcgta aatatcttgt
      661 tcgatcgttc caccggcaaa tgtttctgtt ttaaccacgg tgtttgtttg tgcaggtcgt
      721 gttgcagcac caccatgtag ttttgccatc tcatctgcaa cgaattgtac ttctgtacct
      781 acgatgactt gcgcattttt tccgtcgatg atcttcatac caggtacgcc agtggctttg
      841 attttatttt gatcgatcag gcctgtatct ttgacttgca aacgaaggcg tgtagtacag
      901 ttatcgatcg aagttacatt gtcggctccg cctaatgcag cgtagatttt gcttgcttgt
      961 gccgcatatt tattgtctga attagtcgtt gcagtatcgt catctgaaag atctgcttcc
     1021 tcgcggccag gagtcatcag atggaatttt ttgatagcaa agttaaagcc aaagtagtaa
     1081 atcactgctg ttactaatcc ttggacgatc aacatcaatg gctgattcgc aatcggattt
     1141 ttcaaagata ggaagtaatc gacaaatccg gcactaaagg caaatcctgc tgtccaatgg
     1201 aagaatgcac tcactgctaa agaaatccca gtgaaaattg catgcaagac atataatggc
     1261 caagcaacga acataaatga gaattcaagt ggttctgtta caccagtaaa gaatgaagca
     1321 aaagctgctg ctaacatcaa ggaagctgtt tttgctttgt tttctggacg tgcatttctg
     1381 taaatagcat atgctcctgc tggaagcccg aacatcatga ttgggaaaaa tccagcttga
     1441 tacattcctg ttacgccttt tgttccttca gaagccaaaa atttaccaat atcattgatt
     1501 cctgctacgt caaaccagaa cacggagttc attgcttgat gcaatcctgt agggatcagt
     1561 aaacggttga agaagccata aagacctgca ccaccccagc ctaaactcaa aatgaattta
     1621 gcaaaagaaa ctaaagcaga gtaaaccgga ggccatacga gcagtagcac tgcactgatc
     1681 agcaacatga caaaggcagc caagattggc actagacgct tgccgctaaa gaaagataaa
     1741 gccatcggta attttgcttc gtggaaacga ttataaagag ctgccgcaat caatccggca
     1801 ataataccaa taaatacgtt actgatctga gcaaaagatg gatcaactga ttctggtttg
     1861 atattcaata aagtagctac tgaatcagtt tttaaaacat ttactggaac ttcaaatgcg
     1921 accaaacctg ccaaggcagc agcacctgat ttgtccactg acatccctag tgctaaccca
     1981 acggcaaaca gcaaaggtaa ttgacctaaa actgcgttac cgccagcttg taaaaaatga
     2041 gcgacaatgt cgttactata agatgcccac cagtttccga tccctactag taaagcagca
     2101 gcaggtaaga ccgcaactgg aagttgaagg gaacgtccca ttcgttgtag atatgctttc
     2161 aatttttttc ctcctcatga ttgttaacat ttgtttgtac gattgcgctt cttaaacgct
     2221 cgatatggat ggccaagtaa cccagttctt ctttcgtgat cgcgagctgg tattctttgg
     2281 tcagcaacac acggattttt ttagaaatct tatagctttc tgggtatttt cgtttgacca
     2341 tttctacgat ttccgtgtct aaaacagcat attgttgcgc atgggttcgt tgtagaagca
     2401 gtcgtaaatg attcaccagt cttgaataat tcagtgaaaa tggttctgaa tggatatctg
     2461 tttccaattc tgattccact aaatggatga tgtcagatac aatcgtcact tcacggatac
     2521 tgcgatggtt attgttccga ccgcttcgtc cgctgtgaat atggattgcg atatatcctg
     2581 cttcgtcata agtatatgga atcccaagct cttttgtcag atactctact gcccattgag
     2641 caatactgaa ttcatcactg taaagcactt cgatttctct taaaagtttg ttgcggatga
     2701 cgataccgtt attaatgttc tccgcagaaa aagcaatgtg gtcggtcaaa gcgatcaata
     2761 catgttcatt caacttttcc atcaaaacag tttccgcatg atcaatgatc gtttctgctg
     2821 caaataaaaa gcgttcatca atctgattaa gtaaattttg caacttgatt tgaccttctg
     2881 gttccatgac aaatatccgt tcgacatcac gatcaaaaat caaatcattt ctttttctgt
     2941 caaatccaat cccttttcca atagctactt tttcctgtcc accgtcatct accaatactg
     3001 cattttgatt aaagatcttt ttgattttca tgcgcgcacc ctttttgaag atttggtttt
     3061 cacgtttgct agaccagttg attgcggcca aacaaaaata gacacgaaaa acctcctagg
     3121 gaaaccatgt tcctcagaga tttttcatgc ctagtatgat ctagtcacat gaaacgaatt
     3181 attgttaacg taatcaattt tatatagaca gttatgtttt gtcaattctt tttttataat
     3241 tatagtaatt tactggaatt atcagaaata aaaggaagga acaaattaag aaacttatgt
     3301 tatttaatca ttggatcttt tgcttaactt attcgttgtt aaaaagctga aagcgaagga
     3361 aaaaaactct acttaactgt atttctccgt taggacatct aaaaatttac gagcagcagg
     3421 agaaagaggc tggtcttttt tccaaatgag attcagtgaa gcttgtaatg gcggatcgag
     3481 tgggatgaat actttttccg tcccataagt attgatgatc ccatctagag ctaatgcacc
     3541 aaaagtcccg ttatcgacca tcaaagaagc attgtacaat aagttatatg ttccgacgat
     3601 cgataactga tctatgctga aacctagcca ttcagctagt tgactgtcca ctgacgtttg
     3661 ccgggaaatg atcaaaggaa cagttttcag ttcctgcgga tggatgactg tttgctttgc
     3721 taaaggatga ttccgatgta tcaaaagtcc ccaacgatct tgggctggca gtcgaaatga
     3781 ctggtatttt tgtttgtttg tcggttcgat tacgagtcca aaatcaagta atccgctatc
     3841 cagtttgtct atgatatcat ctgcattccc gctatataaa tgaaactgga tatcaggatg
     3901 cgccttgatc aacgaatgaa ggctatcaga aatgaaagag attgctttag tttcgcctcc
     3961 gccaatgtag atttctccag agatgattgc gtcatttgtt aaattgttcg ccgttttttc
     4021 taccaacgac aagatttctt ttccttttga ataaagatat cgaccagaat ccgtcaactg
     4081 tatctctcgg gagcctcgag tgaaaagtgt cacaccaagt tcttcttcta aatctttcag
     4141 ttgttttgag agagtaggtt gcgtgatatg cagagatttt gctgctcggc tgatattttt
     4201 ttctctagct actgctaaaa aatacgtcag tatacgaata tccatttttt ccctcctgtt
     4261 tttaaaaaag cataccacta agtatagtta aaaggaatag ttaagtatgt tttataagta
     4321 ttagacatca taagccgtcc gttataaagt aaggataaaa ggagggagca aaatgacaag
     4381 cctcatcgaa aaacaaatcg tcaataaaga gattcgagta acggatccgc tctttgaagt
     4441 gatccatcag atccaagcgg aaaacgaaga gcctttagca gcgctgaata ctgggtacca
     4501 tgaaccagca gatatccgca aacggctaga aaatatcatt agtgacaaag tagatgatac
     4561 ggtgactgtt ctgctgcctt tttatacaga tttcggcaaa catattagta tagggaaaaa
     4621 tgtctttatc aatcgtcaag tgatgttcgt tgacttaggt ggcatctgtt tagaagattc
     4681 agtattgatt ggtcctcgtg tcaacctcat cacggtgaac catctaaccg atccaaaaga
     4741 acgaagaggc ttgtcagtaa agccaatcca catcaagaaa aatgcttgga tcggagcagg
     4801 agcaactatt ctgccaggcg taacgattgg cgagaatgcc attgttgcag cgaatgcaac
     4861 tgttacgaaa gatgtcccag acaataccat cgttgcagga atccctgcca aaatcgtcaa
     4921 acctgtcgaa cggattattt gaacagtaag atgaaataag agatagtgag tataagcaag
     4981 agatttttca aaacaggagg agaatagaat gaatgattta tcagaaaaag tgattgtcat
     5041 catgggcgct tcaagcggaa tcggtgaagc aacaacgaag ctattagcag aaaaaggggc
     5101 taaactagtt atagctgcac gccgagaaga tcgcctaaaa gcaataaaag aatctttacc
     5161 agaagctgag ctatatattc aaacagcaga tgtaagagat tttgcacaag tccaagcagt
     5221 tatcgattta gcgatggaaa agttcggtcg aatcgatgta ttgtacaata atgcaggaat
     5281 catgccaacc gctccattag ttgaaggtca ccgtgatgaa tggcaaaata tgcttgatat
     5341 caacatcatg ggtgtgttaa atggaatttc cgccgtactt ccaatcatgg aaaaacaaaa
     5401 atctgggcat atcatttcaa ctgattctgt ggcgggacat gttgtttatc ctgattccgc
     5461 cgtttattgc ggaacaaaat ttgctgtccg tgcaatcatg gaaggattac gtcaagagca
     5521 acggcaaaat aacatcaaat ctacgatcat ctctccagga gctgttcaaa ctgaattata
     5581 tcaaaccatc agcgacaaaa aggctgctct tgaacttcat gaagcgcaaa aagaatgggg
     5641 attaacatct gaagatatag cttctgctgt agcatttgcg atagaaacgc cagaccggat
     5701 gtctgtcagc aacatgatta tccgtccgac gacacaggaa gtataatcca taacggataa
     5761 tatccagaga gaattacttg ttaaatagtt attcaaacga ccatcaattt aaggcgtgaa
     5821 tggagaagaa tattcttcat ttacgtcttt ttatgcagaa aaagcaaatt tattaaaaag
     5881 aaacaaatgt tatttaaata tggacattga cttgctttta cttttttagt tacactgtta
     5941 tttaggaaaa gtttcataat tcaaaggaga aaaaagatga aagcaaagaa tttattattt
     6001 agcgttattc ttttaggaaa tctagcagtt gccaacacaa cagtgctagc tgaagaatcg
     6061 acagaaactg tcgcaactca gacatcgagt tcttcagaaa caggaattga aaacgataca
     6121 gaaagtactt tgcagtcagc tactgtctca gaaaatacaa tttcaaccga agaaccaaca
     6181 actgaaacaa cagaacaaac acaaaccgaa gacagtacat cagcagaagc tcagaacaat
     6241 ccagagaatg cagaagaaat cacgaaccaa ttgacagatg ggcaaacatt gacacatacc
     6301 catcaagcag atttgtctga attcgaaaac tatactggct atgcttttta tgctcgctca
     6361 tctgctaatt ctcaacaagc gttcattgat agtattgcct caactgcaca aagtttggca
     6421 agtgccaatg acttatatgc atcagtcatg attgctcaag ccatcgttga aagtggctgg
     6481 gggaacagta ctttggcttc tgcccctaat tacaatctat ttgggattaa aggaagctat
     6541 aatggccaat ctgttacgat gcctacttcg gaatatgtga atgggcaatg gattacggtg
     6601 aatgccgctt ttagaaaata tccttcgtac aaagaatcat tgcaagataa cgtaacggta
     6661 ttgaagacga cttcttttca gccaggcgtt tactactatt ccggtgcatg gaaaagcaat
     6721 acgaactctt acaaagatgc tacggcttgg ctaacaggtc gttatgccac tgcgcctaat
     6781 tatggttcta cattgaacaa tgtaatcgaa acctataatc tgacacagta tgatacagca
     6841 ccaacttcaa cttctccgat gtatcgtctg tataaccgtc atacaggaga acatttatat
     6901 acattgaatg ccggagaaaa aaattatctg ccaactgtag gctgggaata tgaagggatt
     6961 gcttggcaag caccaaacag cggacaacct gtctaccgtt tatacaatcc ttacagtgga
     7021 gaccatcatt acacaatggc acaatctgag atcaactctt taacaaaaat cggttggcgt
     7081 tatgaaggtc taagttttta ttctggtggt tccaagccaa tttatcgact atttaatcca
     7141 aatgaaaaaa ctggtaccca tcactatacc ttgagtgcta aggaaagaga ttggctaaca
     7201 ccgatgggct ggagatatga aggaatagga ttttatggtt attaaaaaga ggtagtgaaa
     7261 aagctgccct gcatcaagta gtaagaacag ccaaacaaaa acagattttc atgttttttg
     7321 tttggttgaa cttattaccg cagatgcaag tttttgaaca ccgtttactc aaaaaaggtt
     7381 gtgacaacat cttgtcataa cttttttatt actgtttaag catactgatc caatttctaa
     7441 tattcgacgg gattcttgca aaaggcgatt tcggaaattt ttggcggtgt aaaattatct
     7501 actgcagaag agctatcttc tatagtttga taagaatcaa taatcttggt tttagcgttg
     7561 tgctttcttt atcatttttt ccgttcattc tacaaaaaat ttcttttctc tatacttttc
     7621 tattgagagc gtttttttta ttacacagct gattctttga cttttttctt tttttattct
     7681 attattgaca agtcaatcgt tgacgagtca attattagaa aggaggaaat tatgtcttta
     7741 gaagagatta gtcacctttt atatcaaatc aaattagccg atcaaaaaat cgtccagatc
     7801 tttgaagaaa atatcggtat aagtcttact agatacgaga tcatgatgag actgaaagaa
     7861 gaaaatccat tgctacaaag cagtttgcaa gaaaagttgc agattgatca aggagcagtt
     7921 actcgtcatc tgaaggtatt ggaagcaaat ggctatgttt cgcgtcagag aaatcctcag
     7981 aacaaccggg aagtgtatgt agcgctaaca gaaaaagccc agaagaaaat caagcattgt
     8041 gaaatggacc ataaagatac aggttccgtg ctatccccgg ctttcagcga tgtagaaatg
     8101 aaacaatttc taacactttt agataaattg aatacccaac tttgcaatat aacaacagaa
     8161 acgaaagagg ttaataataa tggaacaaaa aaatgatttt tcaacaatta tgactggtag
     8221 aagatccgtt cgcgtatatg atgaaacata caaaatccca cacgaagaaa tgctggaaat
     8281 gatcaaagaa gcgacgactg caccttcttc tgtcaatatg aaaccatggc gctttgtggt
     8341 cgctgaaagc gaggaagcaa aagaaatctt gcgtcctttg atccgtttca atacgagaca
     8401 aaatgatact tcttctgcaa tggtcatgat ttttggcgat atgcaatgtt acgaatatgg
     8461 cgaagaaatc tacaaccaag cttacgaatc agggaagatg ccaaaagaag tcagagatca
     8521 acaattagct gcgatcattc cttattacaa gagtttttca agagaagaaa tgaacgatgt
     8581 agtcaaagtc gattctagct tagcggctat gcaattcatg ttagttgcgc gtgatcatgg
     8641 ctatgaaaca aatccaattg gtggattcga agcagatcag ttggcagagg catttggttt
     8701 ggataaagac cgttatgttc cagttattat tttatcaata ggaaaagcgg tagaagaagg
     8761 ttacgagtct gttcgtttag caccagaaaa gatcactatg ttcgaataaa aggttttcag
     8821 ttactattca gtagctattg ctttttttga atcgtgtgtg gtaacctaat aaaaaaggag
     8881 gtcggaaaaa tgactgcatc gatgaaatta cgtttcgaac ttttgaataa caactaaata
     8941 aattcaaaag acatgtataa acaacaattt catggatgga gtatgtccat tttttcgaac
     9001 gacagtagaa taggtgaaag ctatgacaga tttggtgatt tagtcatagt tatttcgttc
     9061 agagtaggaa aagatgtgat gcagtttttt tgcaaacaga tttttctgct cttttttagt
     9121 atcgataatt gttgttttac atgaaatagg agtgtaaaac atatggaaaa tttagcagta
     9181 aatataacaa atctacaagt cagctttggc aaccagctag aactatctat tgattctctt
     9241 cgtgtctatc agcaagatcg tatagggatc ataggagaaa atggtgtcgg taaatcgact
     9301 ttgctcaaac taatagccgg tgaacttttt cccgatcatg ggaaaatcca aacagagatc
     9361 accttcaact acctgcctca attaacctat ctcgctgaag caaaggacct aaatttggaa
     9421 ttagccagtc atttccagtt aagactggaa gaaacttcag agcggaaatg gagcggaggg
     9481 gaagaacgaa agatcgagtt gatacgtctt ctttcttctt atgaacaagg gatgcttcta
     9541 gacgagccaa caacccatct agatagaaaa agtattgatc gactgattga agagcttcgt
     9601 tattattatg gtacgctggt ttttgttagt catgatcgct attttctaga tgagctagca
     9661 tcgaaaatct gggaagtaaa agacggagaa atccgagagt tttcggggaa ttatagtgcc
     9721 tatctcactc aaaaggaatt ggagaaaaag actcagctac gagaagcaga gtcgatcatg
     9781 aaagagaaaa aacgattgga aaaatcgatc caagaaaaga aaaaacaagc ggaaaagttg
     9841 gaaaaagtgt ccagtaaaaa gaaaaagcaa caaatcagac tggatcggtt gtcttcctct
     9901 aaacaaaaag acagtgtaca aaaagccatc caaaagaatg cgaaaacatt agagagaaga
     9961 ctccaaaaaa taggagaaac aaccaagccg cagcagatga aacaaatccg ttttccagta
    10021 ccaaaatctc ttgaactcca cagccgctat cccatcatgg gacaaaatgt ccaattggaa
    10081 agaagtggga gaacattact ggtaaatggt gattttcagt tttctttagg taaaaaaatc
    10141 gcgattgtcg gtgaaaatgg ttcaggtaag acaaccttat tagaacatat ccgcaaacaa
    10201 ggagaaggaa tccttctctc tccgaaagta agctttcaag tatatcagca aaagggttat
    10261 caaatgacat ctgaagaatc catcattcgt tttgtcatga gacaaacaga gttttcagaa
    10321 tcgcttgtcc gtagtttgct gaatcactta gggtttgctc aggaaacttt gacgaaaccg
    10381 ttatgtacat taagtggggg agaagcgacc cgtctgacga ttgctttgct ttttactaag
    10441 ccaagtaatg tgttgctgtt agatgaaccg actaatttta ttgatatggc aacgatcgaa
    10501 gctttagaga agctaatgca aatatatccg ggaacgattt tgtttacttc tcatgattct
    10561 tactttgtcg agcgtacggc tgatgaagtt tatgaaataa aagggcagaa aataaaaaaa
    10621 gtacttacga gaaattttta aatgtgctac gatgattttc gtgacaaatt taaaggagtg
    10681 gtacagattg cctacaaata aaaaagaagg aataattttt acaacaatga tgtgtttttt
    10741 gatggtcttg gggatgagcg cgtataattt atggctgcat caagatcttc atttatcaag
    10801 tttgttgatt ggtctagtgc ctggattcgt ggtggctttc attttggatg tcttcatcat
    10861 cggtgtgctg gcgaaaaaaa ttgcctttaa actaccagta aatccagaaa gcaaggtcca
    10921 aatgatctta actatttcat gcttgatggt tttaggaatg gtgacatgta tgtctttatt
    10981 cggtgtgatc atggaacaag gaatacctga tcaattattc tctgcttata tgaatgcttg
    11041 gaaaatgaat gtgattgccg ctttaccgtt gcagttgatc atcgttggcc cgctttcaag
    11101 aagtgtgcta aaagcaattc aaagtaatga atgatggaac actgttattt gaaaaaaggc
    11161 cttggcatgc tttttgtcat agtctcttga atgcagttct agaaaaatag tgatccgaac
    11221 gataggtttt ggcctgtcgt tcggatcgct ttttcttttc caactgtatt gctcttttat
    11281 tgaagataat ttgctcttca atagatattt ctagaaaggt tctgtttatc ccttactcaa
    11341 aaaactgctg catttgttct cttacttgct gacaccattg gagttcctgc tgacaaagca
    11401 taattctgcg ctggatcaca acataacgtc caaattcttg tttcttgtct agcgagaggt
    11461 cattcaattt tttttgattt ttttgcatga ttttgttcag ctgttgttct ctagtgaata
    11521 gcagtccagt agctgttgtt ttatcgagcg tcgaaaaagc atagattttt gctagaaatt
    11581 catctttttg cgtaggagcg ggagtttcct ctttgatcca ttcctctaca agagcacgtc
    11641 cttcatcagt caagtggtag atcttttttt gagagtgctc gtctttgtcc aaaacggtca
    11701 cataaccctg ctggtctaac ttggcaagcg ttgtatagat ctgactgtga tgggcttccc
    11761 aaaaaattgt gatcagctgc ttcaattcat acccagaacg tggtttggat aaaagcacgc
    11821 ataataatat ataggctaaa gtattcataa aaatcctacc tctcgtctta ttttctttat
    11881 tatatcacag taaagtttcc acgttttaca tgtgcatatt gacatgtaaa ataaatcatg
    11941 tatgatgcta atagagagaa agggatggaa atattggaga atcaaataga tatacaagaa
    12001 caaacaaatg aagaaacaaa ggggaaaagt tcagcgctag ttgtagcagc tacctgtatg
    12061 atcgctttta tgggagtggg tctagtagac ccaatcttaa aaacgattgc tgcacagtta
    12121 aacgctacgc cagctgaaac gaccctgtta tttactagtt acatgttagt cactggtgtg
    12181 gtgatgctat ttacaggttt cttatctagt cggatcggtt tgaaaaaaac attgatgaca
    12241 ggattgttta tcatcgttgt attcgctggt cttggcggat tatctgggaa tatcggaatg
    12301 ctgattgggt tacgtgccgg ctggggtgtc gggaatgctt tatttgtctc tactgcttta
    12361 gcaacgatcg tcagtatttt agttggtaac acagaaaaag caatcatgat gtatgaagca
    12421 gcacttggct gcggaatggc tgttggccct ctagtcggtg gggtcttggg cagtggttca
    12481 tggcgttatc cattttttgg ggtagcattt ttgatgtttt gcggttttat agccctagcg
    12541 gtacttttac ctgaaactga gaaaccaaag agaaaagtag gcctttggga aggtgtcaaa
    12601 gcgttaagca atcataaact tcgttcagtt ggactaatcg cattgttata taatttcgga
    12661 ttctttactt tacttgcgta tgcgccattt ttattgattg gctattctga attagaagtc
    12721 ggttttgtat tttttggctg gggtgtgctt ctggctattg cttcgatttt cgttgcaccg
    12781 gctcttgagc ggaagtttac gacttatcgg acaattttag cagcatttgt cttattcatt
    12841 atttgtttgc tgttattagg agctggaact tctatgccag tccttgtacc gatcagcatt
    12901 gtgttagcag gatttttcca aggaattatc aatacactgt tgacgacgat tgctatggaa
    12961 ataccaggtc tgcaacgaaa cgttgcttcg tccagctata gttttgtccg ctttttcggt
    13021 ggagctttag caccatttat tgcaggtgtg attggtgaac atattggtga aagctatgcg
    13081 ttttattttg caggtgccat tgttcttatc agtgtatgtt gtatcattta tcaccgtaat
    13141 tattttgcta caaatgaaga agaataagaa atcagaggtt gtgaaaaagc tgtcctgcat
    13201 caagtcataa gaa
//
LOCUS       DAZULR010000187        10809 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.guided.070, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000187 DAZULR010000000
VERSION     DAZULR010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10809
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.guided.070"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..2371
                     /locus_tag="ACG8ZV_002943"
     CDS             <1..2371
                     /locus_tag="ACG8ZV_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFS4998171.1"
                     /translation="VPYNYSFLSPEQKIQVHDSFRQLIAQNRDGKIHALQISTESSIL
                     SAQERSKNEVTGKLKTVAYDKIDQQTDALISMIGENQVDYRFFIGFKLLLNDQEFSMK
                     SLTVEAKNAFTDFVYDVNHKLMGDFVSMSNDEILRFQKMEKLLENKISRRFKIRRLDK
                     DDFGYLIEHLYGQTGTAYEEYEYPLSKKKLEHETLIKTYDLIKPTRCLVEEKQRYLKI
                     QQEDETAYVAYFTINSIVGELDFPSSEIFYYQQQQFTFPIDTSMNVEIVANRKALSTV
                     RNKKKELKDLDNHAWQSDNETSSNVAEALESVNELETNLDQSKESMYKLSYVVRVSAN
                     DLDELKRRCNEVKDFYDDLSVKLVRPFGDMLGLHEEFLPASKRYMNDYIQYVTSDFLA
                     GLGFGATQMLGENEGIYVGYSLDTGRNVYLKPALASQGVKGSVTNALASAFVGSLGGG
                     KSFANNLIVYYAVLYGAQAVIVDPKAERGRWKETLPEISHEINIVNLTSDEKNKGLLD
                     PYVIMKNTKDSESLAIDILTFLTGISSRDGERFPILRKAIRAVTNSEVRGLMKVIEEL
                     RVENTPLSTSIADHIESFTDYDFAHLLFSDGYVEQSISLEKQLNIIQVADLVLPDKET
                     SFEEYTTMELLSVAMLIVISTFALDFIHTDRSIFKIVDLDEAWSFLQVAQGKTLSMKL
                     VRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGLKFAFRSTDLNEIKKTLAFFGVDPEDE
                     NNQKRLRDLENGQCLISDLYGRVGVIQFHPVFEELLHAFDTRPPVRKEV"
     gene            2374..4557
                     /locus_tag="ACG8ZV_002944"
     CDS             2374..4557
                     /locus_tag="ACG8ZV_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HFS4998172.1"
                     /translation="MKPSILNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVTPSGLSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHALMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNMTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRM
                     MRKPRMLMHAHMHRLQRKLGRSVTALGAGSAIASATGKKGQSGSGSSASTQADHSRPN
                     GQEKSTLGKRIGQTIGTVADTKDRMVDTAGNLKEQVKDLPTNARYAVYQGKSKVTDNV
                     HDLTRSISQTKADKASGRKKQQEQRRKTIAERRSEMEQVKQKKQPASSVHERPATKQE
                     QSHDGQTSRQTTVQASYRESQQAKQERPTVKSDSSSLKTERQSNTVQERTVQKPVTST
                     APTDRASQRSITKERQSTVQRVPLQNTKSRPPIKTATIKKGSKKP"
     gene            4554..5555
                     /locus_tag="ACG8ZV_002945"
     CDS             4554..5555
                     /locus_tag="ACG8ZV_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HFS4998173.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDGGFSNIHYGGV
                     DVSAEVLAHKPMVEKVAKEYGIEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLGVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGDEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKFEGWKYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTRHIPLLEAKA
                     GDLVFFHSTYNAGSYITHIGIYLGDNRMFHAGDPIGYADLTSSYWQQHLVGAGRIKQ"
     gene            5570..6484
                     /locus_tag="ACG8ZV_002946"
     CDS             5570..6484
                     /locus_tag="ACG8ZV_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFS4998174.1"
                     /translation="MMKFGKNQNTEKQTPKEKKPRVYKVNPRKKVVIVLWVLLGLSFS
                     FAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWELNDKSIDNRIEN
                     LKAYLTEELQALNVDTVRKDIPVSSSVKGFQIWTVEADGDNQFDVTYSVDQLITEGEN
                     TKTVHSAYIVSVYVDSTGNMVLIKNPTITSIPKKSDYKPKAIESEGTVDSITTNEINE
                     FLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIYNRKDNQVTVSLTVEY
                     IDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            6798..6845
                     /locus_tag="ACG8ZV_002947"
                     /pseudo
     CDS             6798..6845
                     /locus_tag="ACG8ZV_002947"
                     /inference="COORDINATES: protein motif:HMM:NF011335.0"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            6861..8780
                     /gene="tet(M)"
                     /locus_tag="ACG8ZV_002948"
     CDS             6861..8780
                     /gene="tet(M)"
                     /locus_tag="ACG8ZV_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HFS4998175.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            8878..10251
                     /gene="tet(L)"
                     /locus_tag="ACG8ZV_002949"
     CDS             8878..10251
                     /gene="tet(L)"
                     /locus_tag="ACG8ZV_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008493 - tetracycline transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015904 - tetracycline transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HFS4998176.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT
                     SYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS
                     MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV
                     SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTS
                     FLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVY
                     KHSQRDF"
BASE COUNT         3410 a         1934 c         2269 g         3196 t
ORIGIN      
        1 tgttccctac aattactcat ttctaagtcc ggaacagaaa atacaagtac atgattcttt
       61 cagacagctt atcgcacaaa atcgtgatgg caagattcat gctttacaaa tcagtacaga
      121 atccagcata ctttctgcac aagaacgttc caaaaatgaa gtcactggaa agctcaaaac
      181 ggttgcctat gacaaaatcg accaacagac agacgcttta atatccatga ttggcgaaaa
      241 tcaagtggac taccgtttct ttatcggttt taagttgctt ctcaacgatc aggagttttc
      301 tatgaaaagt cttaccgttg aagcaaaaaa tgcttttact gattttgtct atgatgtgaa
      361 ccataagctg atgggcgatt ttgttagtat gagtaatgat gaaatcctgc gttttcagaa
      421 gatggaaaag cttttagaaa ataaaatctc ccgtcgtttc aaaatccgaa gattagataa
      481 ggatgacttc ggctatctga ttgaacacct ttacggacag acaggcactg cctatgaaga
      541 gtatgagtat cctctatcaa agaaaaagct ggaacatgaa acactgatta aaacctatga
      601 cctcattaag cctactcgct gtctggtgga agaaaaacag cgatatttga aaatccagca
      661 ggaagacgaa accgcctatg tagcttactt taccatcaac agtattgtcg gcgaactgga
      721 cttcccgtcc tctgaaatct tctactacca gcaacagcaa tttacctttc cgattgatac
      781 gtcaatgaat gtggaaattg tagcgaatcg taaagcccta tctactgtcc gcaataaaaa
      841 gaaagaactg aaagacttgg ataaccacgc ttggcaaagt gataatgaaa ccagctctaa
      901 tgtggcggaa gctctggaaa gtgtgaacga gctggaaacc aatttagacc aaagcaagga
      961 atctatgtat aagctgtcct atgttgtaag ggtatcagca aatgaccttg acgaacttaa
     1021 acgtcgttgt aatgaagtga aagatttcta tgatgatttg agcgtgaaac tggtacgacc
     1081 ttttggggat atgctgggct tacatgaaga atttttacct gccagcaaaa gatatatgaa
     1141 tgactatatt caatacgtga cctctgattt cctcgctggt ttaggttttg gtgctactca
     1201 aatgctgggt gaaaatgagg ggatttatgt tggctacagc ttagatactg gacgcaatgt
     1261 ctatctgaaa cctgctcttg ccagtcaagg ggttaagggt tcagtaacca atgcgttagc
     1321 gtctgccttt gtcggttcgc tgggtggtgg taaatccttt gcgaataacc ttatcgtcta
     1381 ttatgcagtg ctttatgggg cacaagcagt gattgtagac ccaaaagcag aacgtggcag
     1441 atggaaagaa accttgccag agatttccca tgaaatcaat atcgtcaatc tgacttctga
     1501 tgagaaaaac aaaggcttac ttgaccctta tgtaattatg aaaaatacca aagattctga
     1561 atcactggct attgatattt tgacattcct tacggggatt tcctctcgtg atggggaacg
     1621 cttcccaatc cttagaaaag ccattcgtgc agtaaccaat agtgaagtgc gagggttgat
     1681 gaaagtgatt gaagaattac gggttgagaa tacgccacta agtaccagca tagccgacca
     1741 tatcgaaagt tttacagact atgactttgc ccatctgctt tttagtgatg gttatgtaga
     1801 gcagtctatc agccttgaaa aacaactgaa cattatacag gttgccgact tggtacttcc
     1861 tgacaaggaa acttcctttg aggaatatac cacaatggag ttactatcgg tagcaatgct
     1921 gattgtcatt agtacctttg cgttggactt tatccataca gaccgaagta ttttcaagat
     1981 tgtagactta gacgaagcat ggagcttctt acaggtggca caagggaaaa cactatctat
     2041 gaagctggtt cgtgctggtc gtgctatgaa cgctggggta tatttcgtga cccaaaatac
     2101 agatgacctc ttagatgaaa aactgaaaaa taacctcggc ttaaaatttg cctttcgttc
     2161 cactgacctt aacgagatta aaaaaaccct tgcctttttt ggtgtagacc cagaggacga
     2221 aaacaatcag aagcgattgc gtgatttgga aaacgggcaa tgccttatca gtgatttata
     2281 tggtcgtgtc ggtgtgatac agttccaccc tgtatttgaa gaactgctcc atgcctttga
     2341 taccagacca cctgtgcgaa aagaggtgta aatgtgaaac catcaatatt aaacagaata
     2401 aaatcaaact ggacgctgaa acgtctaggt aaagtggcaa tgacagtggc tttcacactt
     2461 gtgattgcca tttttctttt agccatgctg ggaacggtgg ttcaagctgc gggcttggta
     2521 gatgatacgg tcaatgtggc aaatgaatac agccgatacc cacttgaaaa ctatcaactg
     2581 gatttttatg tggataatag ctggggctgg ctaccgtgga actggtcgga cggaattgga
     2641 aaacaagtca tgtatggact atatgccatt accaatttta tttggacaat cagtctttat
     2701 gtttccaatg cgacgggtta cttagtacag gaagcctatt ccttagactt catttccgct
     2761 acagcagatt ccattggcaa gaatatgcag acccttgcag gggttacgcc tagtggacta
     2821 tcaacagagg gtttctatgt tggattcctt ttactcttga ttttggttct tggggtttat
     2881 gttgcctata caggactgat aaagagagaa accacaaagg caattcatgc cctcatgaat
     2941 tttgtgctgg tttttatcct atcggcttcc tttattgcct acgctcccga ctacattaaa
     3001 aaaatcaatg acttttcatc agacatcagc aacgctagtt tgtcactggg tacaaaaatt
     3061 gtcatgcccc attcagatag tcaaggcaag gacagtgtgg acttgatacg tgacagccta
     3121 ttttccatac aggttcagca accgtggcta ctgcttcaat ataacagttc agacattgaa
     3181 agtattggta ttgaccgtgt ggaaagcctg ctctcaacca gtccagattc caacaatggg
     3241 gaagacagag aaaaaattgt tgcggaagaa attgaagata gaagcaatac caatatgacg
     3301 attacaaaga cgattaaccg tttaggtaca gtcttcttcc tatttgtctt caatattggg
     3361 atttccatat ttgtattcct attaacagga atcatgattt tctcgcaggt actttttatc
     3421 atctatgcta tgtttctgcc tgtgagcttt attttaagca tgattccatc atttgatggt
     3481 atgtcaaaac gagccataac aaagctcttt aataccattt tgacacgagc tggaatcaca
     3541 ttgattatta cgacagcatt tagtatttca accatgctct ataccttatc ggctggttat
     3601 ccgttctttt tgattgcttt tctacagatt gtgacctttg caggaatcta ctttaagctg
     3661 ggcgatttaa tgagtatgtt ttctctacag agtaacgatt ctcaaagtgt gggaagtcgt
     3721 atgatgagaa aacctcgtat gcttatgcac gctcacatgc accgtctaca gcggaaactt
     3781 ggacgctccg tgactgcttt aggggctggg tctgccattg ccagtgctac gggtaaaaaa
     3841 ggacagtcgg gttcgggaag ttctgcgagt acacaagcag atcactctcg accaaacggg
     3901 caggaaaaat caacactagg aaagcgtatc ggtcaaacca tcggtacagt agctgatacc
     3961 aaagacagaa tggtagatac tgctggtaat ttgaaagaac aggttaagga tttgccgacc
     4021 aatgcaagat atgcagtata tcaaggaaaa tctaaagtga cggataatgt ccatgattta
     4081 accagaagta tttctcaaac caaagcggat aaagccagtg gacgcaagaa acagcaggaa
     4141 caaagacgga aaaccattgc ggagcgtcgc tctgaaatgg aacaggtcaa acagaaaaaa
     4201 cagccagctt cttccgttca tgaaagacca gccactaagc aagaacaatc tcatgatgga
     4261 cagacttcaa ggcaaacaac tgtacaggct tcctataggg aatctcaaca agccaaacaa
     4321 gagcgtccaa cagttaagtc cgattcttca agtttaaaaa cggaacgtca aagtaataca
     4381 gttcaagaaa gaacggttca aaagccagta acttcaactg caccaacaga tagagcttca
     4441 caacgttcaa tcacaaaaga acgtcagtct actgttcaaa gagtaccact acaaaataca
     4501 aaaagtagac caccaatcaa aaccgccacc attaagaaag gcagtaagaa accatgaagc
     4561 tgaaaacttt agtgattggt ggttcgggat tattcttgat ggtcttctca ctgcttctgt
     4621 ttgtcgccat tttattttca gatgaacaag atggcggttt ttccaacatt cactatggcg
     4681 gtgtggatgt ttccgcagaa gtgctggctc ataagcctat ggtagaaaaa gttgccaaag
     4741 aatatggaat tgaagaatac gtcaatatac ttcttgcgat tatacaggtg gaatcgggtg
     4801 gtacagcaga agatgttatg cagtcctcgg aatccctcgg tcttccacct aattcattga
     4861 gtacagaaga atccattaag caaggtgtga agtatttcag tgagttatta gccagtagcg
     4921 aaaggcttgg tgtagattta gaatcggtta tccagtccta caattatggt ggtggtttct
     4981 taggatatgt ggctaatcgt gggaataaat atacctttga actggctcaa agtttctcaa
     5041 aagagtattc gggtgacgaa aaagtgtctt accccaatcc catagccata cctatcaatg
     5101 ggggctggcg atacaattac gggaatatgt tttatgtgca actggtaacg cagtatcttg
     5161 tcacaacaga gtttgatgat gatacagtac aagccatcat ggacgaagct ctgaaatttg
     5221 aaggctggaa gtatgtctat ggcggagctt ccccgactac ctcttttgat tgtagcggac
     5281 tgacacaatg gacgtatgga aaagctggaa tcaacttacc acgaacagca caacagcaat
     5341 atgatgtaac ccggcatatc ccattattgg aagcaaaagc cggcgatttg gttttctttc
     5401 attctaccta taacgctggc tcttatatta ctcatatcgg gatttattta ggcgataacc
     5461 gtatgtttca tgcaggcgac cctatcggtt atgccgactt aacaagctct tactggcaac
     5521 agcatttagt gggagcagga cgaatcaaac aataagaaag gacgattcaa tgatgaaatt
     5581 cggaaaaaat cagaatacag aaaaacagac accaaaggaa aagaaacctc gtgtctataa
     5641 ggtcaatcct cgtaaaaagg ttgtgattgt cctatgggta cttttaggac ttagtttcag
     5701 ctttgcgata ttcaagcact ttacagccat tgatacccat accattcatg aaaccaccat
     5761 catagaaaag gaatatgtcg atactcatca tgtggaaaat tttgtagaga actttgcgaa
     5821 agtctactat tcatgggaac taaacgacaa gtccattgat aatcgcatag aaaacctgaa
     5881 agcatatctg acagaggaac ttcaagctct gaatgtcgat acagttcgta aagatattcc
     5941 tgtatcgtct tctgtaaaag gatttcagat atggacggta gaagcagatg gcgacaatca
     6001 atttgatgta acctacagtg tagaccaact cattacagag ggggaaaata caaagaccgt
     6061 ccactctgct tatatagtga gtgtctatgt agacagtact ggaaatatgg tcctcattaa
     6121 gaatccgacc attactagca taccaaagaa atcagactat aaaccaaaag ctattgaaag
     6181 tgagggtacg gttgattcca ttacaaccaa tgaaatcaat gagtttttaa cgacgttctt
     6241 caagctctat cctacagcga cagccagtga actttcctac tatgtgaatg acgggatatt
     6301 aaaaccaatc ggaaaagagt acatctttca agaactggta aatcctattt acaatcgtaa
     6361 ggataatcaa gtcacggtat cgctgacagt ggagtatatc gaccagcaga ccaaagcaac
     6421 gcaggtatct caatttgatt tggtacttga aaagaacggg agtaattgga agattataga
     6481 ataacaaata ttggtacatt attacagcta ttttgtaatc acgtactctc tttgataaaa
     6541 aattggagat tcctttacaa atatgctctt acgtgctatt atttaagtat ctatttaaaa
     6601 ggagttaata aatatgcggc aaggtattct taaataaact gtcaatttga tagtgggaac
     6661 aaataattgg atgtcctttt ttaggagggc ttagtttttt gcacccagtt taagaatacc
     6721 tttatcatgt gattctaaag tatccggaga atatctgtat gctttgtatg cctatggtta
     6781 tgcataaaaa tcccagtgat aagagtattt atcactggga tttttatgcc cttttgggct
     6841 tttgaatgga ggaaaatcac atgaaaatta ttaatattgg agttttagct catgttgatg
     6901 cgggaaaaac taccttaaca gaaagcttat tatataacag tggagcgatt acagaattag
     6961 gaagcgtgga caaaggtaca acgaggacgg ataatacgct tttagaacgt cagagaggaa
     7021 ttacaattca gacaggaata acctcttttc agtgggaaaa tacgaaggtg aacatcatag
     7081 acacgccagg acatatggat ttcttagcag aagtatatcg ttcattatca gttttagatg
     7141 gggcaattct actgatttct gcaaaagatg gcgtacaagc acaaactcgt atattatttc
     7201 atgcacttag gaaaatgggg attcccacaa tcttttttat caataagatt gaccaaaatg
     7261 gaattgattt atcaacggtt tatcaggata ttaaagagaa actttctgcc gaaattgtaa
     7321 tcaaacagaa ggtagaactg tatcctaata tgtgtgtgac gaactttacc gaatctgaac
     7381 aatgggatac ggtaatagag ggaaacgatg accttttaga gaaatatatg tccggtaaat
     7441 cattagaagc attggaactc gaacaagagg aaagcataag atttcagaat tgctccttgt
     7501 accctgttta tcatggaagc gcaaaaagca acatagggat tgagcagctt atagaagtga
     7561 taacgaataa attttattca tcaacataca gaaagaagtc tgaactttgc ggaaatgtct
     7621 tcaaaattga atattcggaa gaaagacaac gtcttgcata tgtacgcctt tatggcggaa
     7681 tcctgcattt gcgggattcg gttagaatat cggaaaagga aaaaataaaa attacagaaa
     7741 tgtatacttc aataaatggt gaattatgta aaattgataa ggcttattcc ggggaaattg
     7801 ttattttgca aaatgagttt ttgaagctaa atagtgttct tggagataca aagctattgc
     7861 cacagagaga gagaattgaa aatccgctcc ctctgctgca aacaactgtt gaaccgagca
     7921 aacctcaaca aagggaaatg ttacttgatg cacttttaga aatctccgac agtgacccgc
     7981 ttctacaata ttatgtggat tctacgacac atgaaattat actttctttc ttagggaaag
     8041 tacaaatgga agtgattagt gcactgttgc aagaaaagta tcatgtggag atagaactaa
     8101 aagagcctac agtcatttat atggagagac cgttaaaaaa tgcagaatat accattcaca
     8161 tcgaagtgcc gccaaatcct ttctgggctt ccattggttt atctgtatca ccgcttccgt
     8221 tgggaagtgg aatgcagtat gagagctcgg tttctcttgg atacttaaat caatcatttc
     8281 aaaatgcagt tatggaaggg atacgctatg gttgcgaaca aggattatat ggttggaatg
     8341 tgacggattg taaaatctgt tttaagtatg gcttatacta tagccctgtt agtaccccag
     8401 cagattttcg gatgcttgct cctattgtat tggaacaagt cttaaaaaaa gctggaacag
     8461 aattgttaga gccatatctt agttttaaaa tttatgcgcc acaggaatat ctttcacgag
     8521 catacaacga tgctcctaaa tattgtgcga acatcgtaga cactcaattg aaaaataatg
     8581 aggtcattct tagtggagaa atccctgctc ggtgtattca agaatatcgt agtgatttaa
     8641 ctttctttac aaatggacgt agtgtttgtt taacagagtt aaaagggtac catgttacta
     8701 ccggtgaacc tgtttgccag ccccgtcgtc caaatagtcg gatagataaa gtacgatata
     8761 tgttcaataa aataacttag tgtattttat gttgttatat aaatatggtt tcttgttaaa
     8821 taagatgaaa tattttttaa taaagatttg aattaaagtg taaaggagga attaattatg
     8881 aagtgtaatg aatgtaacag ggttaaatac aaccaaattt taatttggct ttgcgtttta
     8941 tcttttttta gcgtattaaa tgaaatggtt ttgaacgtct cattacctga tattgcaaat
     9001 gattttaata aaccacctgc gagtacaaac tgggtgaaca cagcctttat gttaaccttt
     9061 tccattggaa cagctgtata tggaaagcta tctgatcaat taggcatcaa aaggttactc
     9121 ctatttggaa ttataataaa ttgtttcggg tcggtaattg ggtttgttgg ccattctttc
     9181 ttttccttac ttattatggc tcgttttatt caaggggctg gtgcagctgc atttccagca
     9241 ctcgtaatgg ttgtagttgc gcgctatatt ccaaaggaaa ataggggtaa agcatttggt
     9301 cttattggat cgatagtagc catgggagaa ggagtcggtc cagcgattgg tggaatgata
     9361 gcccattata ttcattggtc ctatcttcta ctcattccta tgataacaat tatcactgtt
     9421 ccgtttctta tgaaattatt aaagaaagaa gtaaggataa aaggtcattt tgatatcaaa
     9481 ggaattatac taatgtctgt aggcattgta ttttttatgt tgtttacaac atcatatagc
     9541 atttcttttc ttatcgttag cgtgctgtca ttcctgatat ttgtaaaaca tatcaggaaa
     9601 gtaacagatc cttttgttga tcccggatta gggaaaaata taccttttat gattggagtt
     9661 ctttgtgggg gaattatatt tggaacagta gcagggtttg tctctatggt tccttatatg
     9721 atgaaagatg ttcaccagct aagtactgcc gaaatcggaa gtgtaattat tttccctgga
     9781 acaatgagtg tcattatttt cggctacatt ggtgggatac ttgttgatag aagaggtcct
     9841 ttatacgtgt taaacatcgg agttacattt ctttctgtta gctttttaac tgcttccttt
     9901 cttttagaaa caacatcatg gttcatgaca attataatcg tatttgtttt aggtgggctt
     9961 tcgttcacca aaacagttat atcaacaatt gtttcaagta gcttgaaaca gcaggaagct
    10021 ggtgctggaa tgagtttgct taactttacc agctttttat cagagggaac aggtattgca
    10081 attgtaggtg gtttattatc cataccctta cttgatcaaa ggttgttacc tatggaagtt
    10141 gatcagtcaa cttatctgta tagtaatttg ttattacttt tttcaggaat cattgtcatt
    10201 agttggctgg ttaccttgaa tgtatataaa cattctcaaa gggatttcta aatcgttaag
    10261 ggatcaactt tgggagagag ttcaaaattg atcctttttt tataacagga attcaaatct
    10321 ttttgttcca ttaaagggcg cgattgctga ataaaagata cgagagacct ctcttgtatc
    10381 ttttttattt tgagtggttt tgtccgttac actagaaaac cgaaagacaa taaaaatttt
    10441 attcttgctg agtctggctt tcggtaagct agacaaaacg gacaaaataa aaattggcaa
    10501 gggtttaaag gtggagattt tttgagtgat cttctcaaaa aatactacct gtcccttgct
    10561 gatttttaaa cgagcacgag agcaaaaccc ccctttgctg aggtggcaga gggcaggttt
    10621 ttttgtttct tttttctcgt aaaaaaaaga aaggtcttaa aggttttatg gttttggtcg
    10681 gcactgccga cagcctcgca gagcacacac tttatgaata taaagtatag tgtgttatac
    10741 tttacttgga agtggttgcc ggaaagagcg aaaatgcctc acatttgtgc cacctaaaaa
    10801 ggagcgatt
//
LOCUS       DAZULR010000188         9271 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.guided.079, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000188 DAZULR010000000
VERSION     DAZULR010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9271
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.guided.079"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            260..1171
                     /locus_tag="ACG8ZV_002950"
     CDS             260..1171
                     /locus_tag="ACG8ZV_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HFS4998177.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            1324..1809
                     /gene="vanZ-A"
                     /locus_tag="ACG8ZV_002951"
     CDS             1324..1809
                     /gene="vanZ-A"
                     /locus_tag="ACG8ZV_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HFS4998178.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            2328..2612
                     /locus_tag="ACG8ZV_002952"
     CDS             2328..2612
                     /locus_tag="ACG8ZV_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFS4998179.1"
                     /translation="MELAFRESLKKMRGTKSKEKFSQELEMSRSNYSRIESGKSDPTI
                     KTLEQIAKLTNSTLVVDLIPNEPTEPEPETESEQVTLDLEMEEEKSNDFV"
     gene            2978..3277
                     /locus_tag="ACG8ZV_002953"
     CDS             2978..3277
                     /locus_tag="ACG8ZV_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998180.1"
                     /translation="MNHDECKTYIKNSLLEIRKLANIYTLETFKKELEKRNIYLETKS
                     DKYFSSEGEDYIYKLIENNKIIYSISGKKLTYKGKKSFSKHAILKQLNEKANQVN"
     gene            3320..4810
                     /locus_tag="ACG8ZV_002954"
     CDS             3320..4810
                     /locus_tag="ACG8ZV_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HFS4998181.1"
                     /translation="MNIPFVVETVLHDGLLKYKFKNSKIRSITTKPGKSKGAIFAYRS
                     KSSMIGGRGVVLTSEEAIQENQDTFTHWTPNVYRYGTYADENRSYTKGHSENNLRQIN
                     TFFIDFDIHTAKETISASDILTTAIDLGFMPTMIIKSDKGYQAYFVLETPVYVTSKSE
                     FKSVKAAKIISQNIREYFGKSLPVDLTCNHFGIARIPRTDNVEFFDPNYRYSFKEWQD
                     WSFKQTDNKGFTRSSLTVLSGTEGKKQVDEPWFNLLLHETKFSGEKGLIGRNNVMFTL
                     SLAYFSSGYSIETCEYNMFEFNNRLDQPLEEKEVIKIVRSAYSENYQGANREYITILC
                     KAWVSSDLTSKDLFVRQGWFKFKKKRSERQRVHLSEWKEDLMAYISEKSDVYKPYLVT
                     TKKEIREVLGIPERTLDKLLKVLKANQEIFFKIKPGRNGGIQLASVKSLLLSIIKVKK
                     EEKESYIKALTNSFDLEHTFIQETLNKLAERPKTDTQLDLFSYDTG"
     gene            5158..5328
                     /locus_tag="ACG8ZV_002955"
     CDS             5158..5328
                     /locus_tag="ACG8ZV_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998182.1"
                     /translation="MKKFIYRVLENDEVVAIFNEQQYAQDFIAYEKTISDKQFEIEKV
                     DIADWLLQPREF"
     gene            5342..5959
                     /locus_tag="ACG8ZV_002956"
     CDS             5342..5959
                     /locus_tag="ACG8ZV_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFS4998183.1"
                     /translation="MAKIGYARVSSKEQNLDRQLQALQGVSKVFSDKLSGQSVERPQL
                     QAMLNYIREGDIVIVTELDRLGRNNKELTELMNQIQIKGATLEVLNLPSMNGIEDENL
                     RRLINSLVIELYKYQAESERKKIKERQAQGIEIAKKKGKFKGRQHKFKENDPRLKHAF
                     DLFLNGLSDKEVEEQTGINRRTFRRYRARYNVTVDQRKNNEKRDS"
     gene            5959..6636
                     /locus_tag="ACG8ZV_002957"
                     /pseudo
     CDS             5959..6636
                     /locus_tag="ACG8ZV_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
     gene            6947..7444
                     /locus_tag="ACG8ZV_002958"
     CDS             6947..7444
                     /locus_tag="ACG8ZV_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombinase"
                     /protein_id="HFS4998184.1"
                     /translation="MLFLRDGEIKATLTTMMNKLAFSHKLILEPLFKSVSQIDEESDC
                     ERMDAIDKLMEQLLEERNTLIALMSKGFLEPALFNQERNVLDSEIKNLTTEKTNLVTN
                     SASGVLRANEIKDLINYVSADNFNGDYTEELFEEFVVNIIVNSRDELTFNLKCGLSLK
                     EKVVR"
     gene            7445..7861
                     /locus_tag="ACG8ZV_002959"
     CDS             7445..7861
                     /locus_tag="ACG8ZV_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HFS4998185.1"
                     /translation="MAYIPYGYKIQDGVVTVDEKAAGQVKVFFEKYISGLSLTVAGEQ
                     AGIEKTHSVMGRILKNVNYLGNDTYPAIIDKEIFDKAEEVRDKRAKDLGRVVELAAFT
                     SPPPKERFKMKKADNKMPVDPFERAEYLYSLIESEE"
     gene            7881..>9271
                     /locus_tag="ACG8ZV_002960"
     CDS             7881..>9271
                     /locus_tag="ACG8ZV_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018659190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFS4998186.1"
                     /translation="MVIPARKRVGSTAAKEKIKKLRVAAYCRVSTETEEQNSSYEVQV
                     SHYTEFIKKNNEWEFAGIFADDGISGTNTKKRDEFNRMIAECMDGNIDMVITKSISRF
                     ARNTLDCLQYIRQLKDKNISVYFEKENINTTDAKGEVLLTIMASLAQQESQSLSQNVK
                     LGLQYRYQQGKVQVNHKRFMGYTKDEDGNLTIVPEEAEIIKRIYREYLEGQSLVGIGR
                     ALEKDGILTAAGKPRWRPESVKKILQNEKYIGDALLQKTVTVDFLTKKRVKNEGHVPQ
                     YYVENSHEAIIPKELFLQAQEEIHRRSNIYTGEGKNKRIYSSKYALSAITFCGDCGDI
                     YRRVYWNIHGRKEFVWRCVTRIEQGPEVCKNRTVKEDELYGAVMTAINKLLAGGNNMI
                     KTLEENIHAVIGETTEYQISEINNSLEEKQKELIKLANKGQDYDHLADEIDELRDKRQ
                     ILLVEDASLSGEN"
BASE COUNT         3392 a         1429 c         1834 g         2616 t
ORIGIN      
        1 ccttatttga tagtagattt aaaactttgc aacagaaccc ccattgtcaa caggcagttc
       61 agcctcgtta aattcagcat gggtatcact tatgaaaatt catctacatt ggtgataata
      121 gtaaatccag tagggcgaaa taattgactg taatttacgg ggcaaaacgg cacaatctca
      181 aacgagattg tgccgtttaa ggggaagatt ctagaaatat ttcatacttc caactatata
      241 gttaaggagg agactgaaaa tgaagaagtt gtttttttta ttgttattgt tattcttaat
      301 atacttaggt tatgactacg ttaatgaagc actgttttct caggaaaaag tcgaatttca
      361 aaattatgat caaaatccca aagaacattt agaaaatagt gggacttctg aaaataccca
      421 agagaaaaca attacagaag aacaggttta tcaaggaaat ctgctattaa tcaatagtaa
      481 atatcctgtt cgccaagaaa gtgtgaagtc agatatcgtg aatttatcta aacatgacga
      541 attaataaat ggatacgggt tgcttgatag taatatttat atgtcaaaag aaatagcaca
      601 aaaattttca gagatggtca atgatgctgt aaagggtggc gttagtcatt ttattattaa
      661 tagtggctat cgagactttg atgagcaaag tgtgctttac caagaaatgg gggctgagta
      721 tgccttacca gcaggttata gtgagcataa ttcaggttta tcactagatg taggatcaag
      781 cttgacgaaa atggaacgag cccctgaagg aaagtggata gaagaaaatg cttggaaata
      841 cgggttcatt ttacgttatc cagaggacaa aacagagtta acaggaattc aatatgaacc
      901 atggcatatt cgctatgttg gtttaccaca tagtgcgatt atgaaagaaa agaatttcgt
      961 tctcgaggaa tatatggatt acctaaaaga agaaaaaacc atttctgtta gtgtaaatgg
     1021 ggaaaaatat gagatctttt attatcctgt tactaaaaat accaccattc atgtgccgac
     1081 taatcttcgt tatgagatat caggaaacaa tatagacggt gtaattgtga cagtgtttcc
     1141 cggatcaaca catactaatt caaggaggta aggatggcgg aatgaaacca acgaaattaa
     1201 tgaacagcat tattgtacta gcacttttgg ggtaacgtta gctttttaat ttaaaaccca
     1261 cgttaactag gacattgcta tactaatgat acaacttaaa caaaagaatt agaggaaatt
     1321 atattgggaa aaatattatc tagaggattg ctagctttat atttagtgac actaatctgg
     1381 ttagtgttat tcaaattaca atacaatatt ttatcagtat ttaattatca tcaaagaagt
     1441 cttaacttga ctccatttac tgctactggg aatttcagag agatgataga taatgttata
     1501 atctttattc catttggctt gcttttgaat gtcaatttta aagaaatcgg atttttacct
     1561 aagtttgctt ttgtactggt tttaagtctt acttttgaaa taattcaatt tatcttcgct
     1621 attggagcga cagacataac agatgtaatt acaaatactg ttggaggctt tcttggactg
     1681 aaattatatg gtttaagcaa taagcatatg aatcaaaaaa aattagacag agttattatt
     1741 tttgtaggta tacttttgct cgtattattg ctcgtttacc gtacccattt aagaataaat
     1801 tacgtgtaag atgtctaaat caagcaatct gatctttcat acacataaag atattgaatg
     1861 aattggatta gatggaaaac gggatgtggg gaaactcgcc cgtaggtgtg aagtgagggg
     1921 aaaaccggtg ataaagtaaa aagcttacct aacactatag taacaaagaa agcccaatta
     1981 tcaattttag tgctgaggaa ttggtctctt taataaattt ccttaacgtt gtaaatccgc
     2041 attttcctga cggtaccccc actagcagcc atgctttttt tgaatctttg taggacgttt
     2101 taaagagaat tacccacttt aaaattaaac atgcgcttag aatcgcttta ggaaacacga
     2161 tccagtccaa taatcgtcga taaaaacttt tgaaaaaggt tggtgaaatt acctactttt
     2221 ggaataatca caaatcacaa gtgattaatc acttgtttat taagatatta aaagctataa
     2281 tttaaataaa gcgtgaattt tattacacaa aaagaggggg gagaaacttg gaactagcat
     2341 ttagagaaag cttaaaaaag atgagaggta ccaaatcaaa agaaaaattc tcccaagaat
     2401 tagaaatgag tagatcaaat tattcacgaa tagaatcagg aaaatcagat ccaaccataa
     2461 aaacactaga acaaattgca aagttaacta actcaacgct agtagtggat ttaatcccaa
     2521 atgagccaac agaaccagaa ccagaaacag aatcagaaca agtaacattg gatttagaaa
     2581 tggaagaaga aaaaagcaat gacttcgtgt gaataatgca cgaaatcgtt gcttattttt
     2641 tttaaaagcg gtatactaga tataacgaaa caacgaactg aatagaaacg aaaaaagagc
     2701 catgacacat ttataaaatg tttgacgaca ttttataaat gcatagcccg ataagattgc
     2761 caaaccaacg cttatcagtt agtcagatga actcttccct cgtaagaagt tatttaatta
     2821 actttgtttg aagacggtat ataaccgtac tatcattata tagggaaatc agagagtttt
     2881 caagtatcta agctactgaa tttaagaatt gttaagcaat caatcggaaa tcgtttgatt
     2941 gctttttttg tattcattta tagaaggtgg agtttgtatg aatcatgatg aatgtaaaac
     3001 ttatataaaa aatagtttat tggagataag aaaattagca aatatctata cactagaaac
     3061 gtttaagaaa gagttagaaa agagaaatat ctacttagaa acaaaatcag ataagtattt
     3121 ttcttcggag ggggaagatt atatatataa gttaatagaa aataacaaaa taatttattc
     3181 gattagtgga aaaaaattga cttataaagg aaaaaaatct ttttcaaaac atgcaatatt
     3241 gaaacagttg aatgaaaaag caaaccaagt taattaaaca acctatttta taggatttat
     3301 aggaaaggag aacagctgaa tgaatatccc ttttgttgta gaaactgtgc ttcatgacgg
     3361 cttgttaaag tacaaattta aaaatagtaa aattcgctca atcactacca agccaggtaa
     3421 aagcaaaggg gctatttttg cgtatcgctc aaaatcaagc atgattggcg gtcgtggtgt
     3481 tgttctgact tccgaggaag cgattcaaga aaatcaagat acatttacac attggacacc
     3541 caacgtttat cgttatggaa cgtatgcaga cgaaaaccgt tcatacacga aaggacattc
     3601 tgaaaacaat ttaagacaaa tcaatacctt ctttattgat tttgatattc acacggcaaa
     3661 agaaactatt tcagcaagcg atattttaac aaccgctatt gatttaggtt ttatgcctac
     3721 tatgattatc aaatctgata aaggttatca agcatatttt gttttagaaa cgccagtcta
     3781 tgtgacttca aaatcagaat ttaaatctgt caaagcagcc aaaataattt cgcaaaatat
     3841 ccgagaatat tttggaaagt ctttgccagt tgatctaacg tgtaatcatt ttggtattgc
     3901 tcgcatacca agaacggaca atgtagaatt ttttgatcct aattaccgtt attctttcaa
     3961 agaatggcaa gattggtctt tcaaacaaac agataataag ggctttactc gttcaagtct
     4021 aacggtttta agcggtacag aaggcaaaaa acaagtagat gaaccctggt ttaatctctt
     4081 attgcacgaa acgaaatttt caggagaaaa gggtttaata gggcgtaata acgtcatgtt
     4141 taccctctct ttagcctact ttagttcagg ctattcaatc gaaacgtgcg aatataatat
     4201 gtttgagttt aataatcgat tagatcaacc cttagaagaa aaagaagtaa tcaaaattgt
     4261 tagaagtgcc tattcagaaa actatcaagg ggctaatagg gaatacatta ccattctttg
     4321 caaagcttgg gtatcaagtg atttaaccag taaagattta tttgtccgtc aagggtggtt
     4381 taaattcaag aaaaaaagaa gcgaacgtca acgtgttcat ttgtcagaat ggaaagaaga
     4441 tttaatggct tatattagcg aaaaaagcga tgtatacaag ccttatttag tgacgaccaa
     4501 aaaagagatt agagaagtgc taggcattcc tgaacggaca ttagataaat tgctgaaggt
     4561 actgaaggcg aatcaggaaa ttttctttaa gattaaacca ggaagaaatg gtggcattca
     4621 acttgctagt gttaaatcat tgttgctatc gatcattaaa gtaaaaaaag aagaaaaaga
     4681 aagctatata aaggcgctga caaattcttt tgacttagag catacattca ttcaagagac
     4741 tttaaacaag ctagcagaac gccctaaaac ggacacacaa ctcgatttgt ttagctatga
     4801 tacaggctga aaataaaacc cgcactatgc cattacattt atatctatga tacgtgtttg
     4861 ttttttcttt gctgtttagc gaatgattag cagaaatata cagagtaaga ttttaattaa
     4921 ttattagggg gagaaggaga gagtagcccg aaaactttta gttggcttgg actgaacgaa
     4981 gtgagggaaa ggctactaaa acgtcgaggg gcagtgagag cgaagcgaac acttgatttt
     5041 ttaattttct atcttttata ggtcattaga gtatacctat ttgtcctaat atgattttag
     5101 cagtataatt gacttggtga ataggtcatt taagttgggc ataataggag gagtaaaatg
     5161 aaaaaattta tttatcgagt tttagaaaat gacgaagtgg tggctatttt taatgagcaa
     5221 caatatgcgc aagattttat cgcttacgaa aagacaattt ctgataagca atttgaaatt
     5281 gaaaaagtag atattgctga ttggttattg caaccgagag aattttagag gttggttgaa
     5341 aatggctaaa attggttatg cacgtgtcag tagcaaagaa cagaacttag atcggcaatt
     5401 acaagcgtta cagggcgttt ctaaggtctt ttcagacaaa ttaagcggtc aatcggtcga
     5461 acgcccacaa ttacaagcta tgcttaacta tattcgtgaa ggggatattg ttattgttac
     5521 tgaattagat cgattaggac gaaataataa agaattaaca gaattgatga atcaaattca
     5581 aattaagggg gcaaccctgg aagtcttaaa tttaccctca atgaatggta ttgaagatga
     5641 aaatttaagg cgtttgatta atagccttgt cattgaattg tacaagtatc aagcagaatc
     5701 agaacgaaaa aaaattaagg aacgtcaggc acaaggaatc gaaattgcta agaaaaaagg
     5761 caaattcaaa ggtcgtcagc ataaatttaa agaaaatgat ccacgtttaa agcatgcttt
     5821 cgatttgttt ttgaatggtt tatccgataa agaagttgaa gaacaaactg gaatcaatcg
     5881 ccgaacgttt agaaggtatc gagcaagata taacgtgaca gtcgatcaaa gaaaaaacaa
     5941 tgaaaagagg gatagttaat gagtacggtt attttagctg aaaaaccaag ccaggcatta
     6001 gcctacgcaa gtgctttaaa acaaagcacc aaaaaagacg gttattttga gatcaaagac
     6061 ccactattta cagatgaaac gtttatcacc tttggttttg ggcatttagt ggaattagca
     6121 gaaccaggtc attatgacga aaagtggcaa aattggaaac ttgaatcttt gccgattttt
     6181 cctgatcgat acgattttga agttgcaaaa gataagggaa agcagtttaa aattgttgct
     6241 gaacttctca aaaaggcaaa tacaattatt gtcgcaacag atagcgacag agaaggtgaa
     6301 aatatcgcct ggtcgattat ccataaagca aatgcctttt ctaaagataa aacgtataaa
     6361 agattatgga tcaatagctt agaaaaagat gtgatccgaa gcggttttca aaatttgcaa
     6421 ccaggaatga attactatcc cttttatcaa gaagcgcaaa cacgccaaat tgccgattgg
     6481 ttgatcggca tgaacgcaag ccctttatat accttgaatt tacaacaaaa aggcgtacaa
     6541 ggtacatttt cattaggacg tgtacaaaca ccgactttat atctcattta tcaacgccag
     6601 gaagcaatag aaaactttaa aaaagaacct tttttcctga ataattcata gttttactaa
     6661 tagtctttcc taacattgat ttaatagtct ttaaagtatt ctgcttcatc acccattagg
     6721 tgatgaaaaa agaacccctt tctgatttag cggacaaata ctttgaccta atctcagaag
     6781 atataaaaga aaaaataata aaatatccga tttatacttt gtataaagaa ctaaagtagt
     6841 tagcaaatca tttacagcaa atcactatgt tccacatacc attttacata cttaccttat
     6901 ccacgacaca tgttgagata gtatcgaaga taaagaaagt tgctccatgt tgtttttgcg
     6961 agatggggaa atcaaagcca cattgacaac catgatgaat aagcttgctt tcagtcataa
     7021 gctaatccta gaaccacttt tcaagtcagt tagccaaatc gatgaagaaa gcgactgtga
     7081 aagaatggac gctattgata agctaatgga gcaactattg gaagaacgca atacccttat
     7141 tgcactgatg tccaaaggtt tcctagaacc tgctcttttt aatcaggaac gaaatgtttt
     7201 agatagtgag attaaaaatc ttactaccga aaaaacaaac ctggtaacga actctgcgag
     7261 tggggttttg cgagcaaacg agataaagga cctcattaat tatgtgtcag cagataattt
     7321 taatggtgac tacacggaag aactatttga agaatttgta gtgaacatca ttgtaaattc
     7381 cagggatgag ctgacattca atttgaaatg cggtctttcc ctgaaagaaa aggtggtgag
     7441 ataaatggca tatattccat atggatacaa aattcaagat ggagtggtta ctgtcgatga
     7501 aaaggcagca ggtcaagtaa aggtattctt tgagaaatac atatcaggac tatcccttac
     7561 agtggctggc gaacaggcag gtattgaaaa gacacattct gtgatggggc gcattttgaa
     7621 aaacgtcaac taccttggaa atgatacgta tccagcaatt attgataaag agatatttga
     7681 taaagctgaa gaagttagag ataaacgtgc aaaggattta ggacgagtgg tagagcttgc
     7741 cgctttcacc tctccccctc ccaaagaacg attcaaaatg aaaaaggcag ataataagat
     7801 gccagtggat ccttttgaac gagcagaata cttatacagt ctgatagaaa gcgaggaata
     7861 aagtgacaga gaaaaatata atggttattc ctgctcgtaa aagagtagga agtacagccg
     7921 caaaagaaaa gataaagaaa cttcgtgttg ctgcctattg ccgtgtttct acagaaacag
     7981 aagaacaaaa ttctagctat gaggttcagg tctcacacta tacagagttt ataaagaaaa
     8041 ataatgaatg ggagtttgct ggcatctttg cagatgatgg tatctctggt acgaacacta
     8101 aaaagcgtga cgaatttaat cgcatgattg cagagtgtat ggacggtaac atcgacatgg
     8161 ttattacaaa atccatcagc cgatttgcgc gtaacaccct agactgcctt caatacatta
     8221 gacagctcaa ggataagaac atatcagttt attttgagaa agagaacatc aacaccacgg
     8281 atgccaaagg tgaggttttg ctgactatta tggcatcttt ggcacagcag gaaagccaga
     8341 gcctttcaca aaacgttaag cttgggctac agtaccgata ccaacaagga aaggtgcagg
     8401 tcaaccataa gcgatttatg ggctacacga aagatgaaga tggaaattta actattgtcc
     8461 ccgaagaagc tgagattatc aaacgcatct accgagaata ccttgagggt cagagtctag
     8521 tgggcattgg tcgagccctt gaaaaggatg gtattttaac agcagcggga aaaccaagat
     8581 ggcgaccaga atcagttaag aagatacttc aaaacgaaaa atacatcgga gatgcccttc
     8641 tgcaaaagac tgtcacagta gattttctga ccaagaaacg agtgaaaaat gaagggcatg
     8701 ttccccaata ttatgttgaa aatagccatg aagcgattat tcctaaagag ttatttttgc
     8761 aggcgcaaga agaaattcat cggagaagca atatctacac aggagaaggc aagaacaaaa
     8821 gaatttacag tagcaagtac gctttaagtg ccatcacctt ctgtggagat tgtggcgata
     8881 tttatagacg ggtctattgg aatatccacg gaagaaaaga atttgtctgg cgatgcgtga
     8941 ctagaatcga gcaaggtcct gaagtttgta agaaccgaac cgtaaaagaa gatgaacttt
     9001 atggtgcagt aatgactgcg attaataagc tacttgcagg tgggaacaat atgataaaga
     9061 cactggaaga gaatattcat gctgtgattg gcgaaaccac agaataccaa atttcagaga
     9121 ttaacaactc actagaggaa aaacaaaaag aactaatcaa gctggcgaac aagggtcaag
     9181 actatgacca cttagcagat gagattgatg agctgagaga caagcgacag atccttttag
     9241 tagaagatgc ctccctcagt ggcgagaacg a
//
LOCUS       DAZULR010000189         8097 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.guided.086, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000189 DAZULR010000000
VERSION     DAZULR010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8097
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.guided.086"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            144..1580
                     /locus_tag="ACG8ZV_002961"
     CDS             144..1580
                     /locus_tag="ACG8ZV_002961"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFS4998187.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            1769..4216
                     /locus_tag="ACG8ZV_002962"
     CDS             1769..4216
                     /locus_tag="ACG8ZV_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HFS4998188.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            4446..5513
                     /gene="rlmN"
                     /locus_tag="ACG8ZV_002963"
     CDS             4446..5513
                     /gene="rlmN"
                     /locus_tag="ACG8ZV_002963"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HFS4998189.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            5503..5709
                     /locus_tag="ACG8ZV_002964"
     CDS             5503..5709
                     /locus_tag="ACG8ZV_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998190.1"
                     /translation="MPNNRILLVFSITIKGAVFLIKELFNLNKRKDSIAKAIKLFLTR
                     KTLIKQRNVLNLMTACLMGVLAII"
     gene            complement(5706..6809)
                     /locus_tag="ACG8ZV_002965"
     CDS             complement(5706..6809)
                     /locus_tag="ACG8ZV_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HFS4998191.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            7362..7910
                     /gene="aac(6')"
                     /locus_tag="ACG8ZV_002966"
     CDS             7362..7910
                     /gene="aac(6')"
                     /locus_tag="ACG8ZV_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HFS4998192.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         2709 a         1380 c         1755 g         2253 t
ORIGIN      
        1 ccattttcac aaaatttttc ttactactcg aaactaagcg actttttcac aacctccttt
       61 acataatttt attttgttgt ggaaggggtt tcgtgttatt ctaaaagagg aacgattgaa
      121 ggttatagga aaggaagaga tgaatggaac acaaagaact tacctcattt ccaaaagatt
      181 ttctgtgggg ctctgcttct gcagcgtatc aagtagaagg agcttggcaa gaagatggga
      241 aaggagaatc agtctgggat cgatttgtac ggatacctgg aaagacattt aaaggaacga
      301 acggtgattt ggcagtagac cactatcatc gttataaaga agatattgct ttaatgaaag
      361 aacaaggtct gaaagcttac cgcttctctg tagcttggac acggattttt cctaatggac
      421 gaggagaagt caatcaagct gggctcgctt tttatgagag attgatcgac gaattgattg
      481 aaaacgatat tgaacctatg ttgactttat atcattggga tcttccacaa gcattgcaag
      541 atgaatataa tggttgggaa tcacgtcaga tcattgaaga tttcactcat tatgcagaaa
      601 cattatttga ggcattccgc gggaaagtcc attactggat tagtttgaat gaacaaaata
      661 tcttcacttc attaggttat ttgttagcag cacatccgcc aggtgtgaca gacccgaaac
      721 gaatgtatga agttaaccat attgctaatt tagcaaatgc atctgtcatc aataaatttc
      781 acgagttaga aatgcctgga aaaatcggac caagctttgc gtatacgcca aattatccaa
      841 ttgacagtaa tcctgaaaat gttctggctg ctgaaaatgc agaagacctg atggccaatt
      901 attggatgga tgtctatatg tggggaaaat atccgattgc tgccatgagg ttcttagaag
      961 aaaaaggatg ggcaccaacg attgaagctg gcgatgcaga attgctagaa tctgctaaac
     1021 cagattttct tgggatcaat tactatcaaa cggcgacgaa tgcattcaat ccattaaacg
     1081 gagttggtgc tggaaaaatg aatacgacag gaaaaaaagg ttcatcagaa gaaactggag
     1141 ttcctggaat gtataaaaaa gttgagaatc catttgtcga acgaacaaat tgggactggg
     1201 agattgaccc agaaggatta aggatcggac tgcgtcgtat cacaagccgt taccgcatgc
     1261 cggtactgat tacggaaaat ggcttaggag agtatgacaa gttgacagaa gataaacaaa
     1321 tccatgacga ctatcgaatc aattacttac aaagccacgt caaagccatc aaagaagcaa
     1381 tttcggatgg agcagaagtc ctaggctatt gcacctggtc ttatacagat ttgcttagct
     1441 ggctgaacgg ttatcaaaag cgatatggat ttgtatatgt tgatcaagac gaaacacaag
     1501 aaggatcttt ggaacgatat aagaaagaca gttattactg gtaccaaaaa ctgattgaag
     1561 aaaatggaga gaacctttag ttcacatact taaaacaaga aggtacggct ggatatggcc
     1621 gtgccttttc ttgataaaat catttagaaa ttaagaaaaa ctgtaaaata agctgaaaaa
     1681 tgaaagaaag cgtcagttct ttcaaacaaa actttagttc ccttactttt ttttgtataa
     1741 tgaaacttga tgaaatgagg gataataaat ggcacaaaag aaacggccta ctaaaaaaag
     1801 gaaaaagacg aaaaaaacga aaaagcaaaa acagcagcag gaacaaatgc tgacgattgg
     1861 tgttgggttt gccttgattt tatttgctgt cttcggcttt ttaaaattag gttttttagg
     1921 aatattgatt gcaaacggct ttcggatcat tgcaggaaat acttaccaaa tcctctgtct
     1981 tttattagcc gtattaggat tttggattgt cattaagaat acagagtttt caattggtaa
     2041 aaaccgacgc tggtttggcg gcatactctt ttatttcggt atcttattat tgttacatgc
     2101 ccatttattt ggcaaactcc atactgggga accaaatatc atggggacga catgggattt
     2161 gttagccagt gatataaaac aaagtcaagt agacaataac gttggtggtg ggatgattgg
     2221 agcaatcctt tatcatttta cttacttctt gattgcacag cctggaagtt atttagcagc
     2281 agtgctatta ctggcaggag gagcattcct gttcagtaat ctggaaggct atcagctgtt
     2341 aaatggtatc caatcaattg gagaacgagt acaggaatta ttggaaggtg atcctgccaa
     2401 gcaagctcga aagcaagcgg caaaggaaga gagaatgaaa cagcgcgcag aagcgaaaga
     2461 agcaaggcgc ttagctgcaa aagaagctgc agaaaaagaa gctgcagaat atgagaagaa
     2521 aaaagcggtg agccagcaaa gggaaaatac tgctgatgaa tggcaggaac cagaaaatac
     2581 agagccggag cagctaagtt ttgttccaat cgacagtttt caagaaaata tccatcctgc
     2641 gaatctagag aaaccagtac cagatacacc aaaacagacc aatacagcag aaggtttttc
     2701 agatgagttg ccagaggatg acggtacctc attagaattt gagattgaag cagaacagga
     2761 aaatcaagac tatgaattac cgacagttga tttgcttgat tctataccaa ctgtggatca
     2821 aagtgatgag tataaaaaaa ttgaaaaaaa tatcggcgta ttagaacaaa ctttccaaag
     2881 tttcggtgtc gatgccaagg tcgtcaaagc cagcttagga ccatccgtca caaaattcga
     2941 agtccagccg gctgtagggg taaaagtaag taaaattgtg aacttaacag atgatatcgc
     3001 gcttgcttta gcggcgaaag atgtccggat ggaagcaccg attccaggta aatcactgat
     3061 tggtattgaa gtaccaaatg gaaagatcag tatggtttcc tttagagaaa tcatcgaagc
     3121 acaaccaaac cacccagata aattactaga agtaccttta ggacgtgatg tttctggacg
     3181 ggtacaaacg gctgatcttt cgaagatgcc tcacttactc gtggctggtt cgactggtag
     3241 tgggaagtca gtagcaatta atgggattat cacaagtata ttaatgcgtg ctaagcccca
     3301 tgaagtaaaa ctgatgatga tcgatccgaa aatggttgaa ttgaatatgt acaacggcat
     3361 acctcatctg ttgacgccgg tcgtgacgaa ccctagaaaa gcagcgcaag ccttacaaaa
     3421 agtagtacaa gaaatggaag aacgatatga aaaattcgcg gcaaccggag taagaaatat
     3481 ttctggttac aatgaatttg ttcaacagaa aaacttggaa aacggaacga aacatccaac
     3541 cttaccattc atcgtagtga tcgtagatga attagctgat ttgatgatgg tagccagcaa
     3601 tgaagttgaa gatgcgatta ttcgtttagc gcaaatggct cgggcagcgg ggattcatat
     3661 gatcctagct actcaacgtc caagtgtgga tgttatcaca ggaatcatca aagcaaatgt
     3721 accttccaga atggcatttg cggtatcaag cggtacagat tctcggacga tcattgattc
     3781 taatggggca gaaaagctct tagggcgagg agatatgcta ttcttgccaa tgggtgagaa
     3841 taaaccgatc cgtgtgcaag gagcattcat ttctgaccac gaagtagaac gggtcgttca
     3901 atttgttaca gatcagcaag aagctcatta tgaagagaaa atgatgccga cagatgaagt
     3961 tgaaacgaca ggtgctccag aacagccaca agatgagctg tttgaagaag caaaagcact
     4021 tgtcgttgaa atgcaaacgg caagtatttc ccttctccaa agaagatttc ggatcggtta
     4081 caaccgagca gcacgtttag tagatgaact ggaagctcat ggagttgttg gcccgtcaga
     4141 aggaagcaag cctcggaaag tattcattga gcaggaagaa acatcagaaa cgttgccgga
     4201 cgataatgac atgtaaaact tgtgtgatga agggttgaaa aacgaataac caataaaaag
     4261 acaaggcatg atgataccaa aagaaaaaat ggtttttttc catcttttct aatacggtat
     4321 gatgtcttgt ctttttagtt tttgtgagat taaagttcta ttcgatttat ttgtgaagta
     4381 ttgcattaag gaaatgaatc atgtatagta tgtagcgaaa ctttgagaaa aagagggaaa
     4441 atactttgga aaaacagtcc atttatggct tgacgaatga agaattaatc aattggttta
     4501 tagaaaacgg cgagaaaaaa ttccgagctg cccaagtttg ggaatggttg tatcaaaaac
     4561 gtgtaagtaa tttcacagaa atgacgaatc tatcgaaaca attgatcgaa aaattatcgg
     4621 agcattttat catcaatcct ctaaaacaga tggtcgtcca agaagcttcg gatggtacag
     4681 taaaatattt gtttgaactc cctgataaaa acatgattga gactgtactg atgagacaag
     4741 aatatggctt gtcagtttgt gtgacgacac aagtaggatg taatatcggc tgtacgtttt
     4801 gtgcaagcgg gctgctcaaa aagaaccgtg atctgactgc tggagaaatt gttgcacaga
     4861 tcatgatggt ccaacattat tttgatgagc gcaatcttgg cgaacgcgtt tcacatgtcg
     4921 ttgtaatggg gatcggtgag ccatttgata attacgacaa tgtaatggac tttttgcata
     4981 tcatcaatga tgccaaagga ttggcaattg gtgctcggca cattacagtt tccactagtg
     5041 gattagcaca caaaatcaag gaattcgcta ataacggctt gcaagtcaat ctggctattt
     5101 ccttgcacgc gccgaataat gaggtgcgaa catcgatcat gcggatcaac cgaagtttcc
     5161 caattgagaa attgatggaa gctgtggatg agtatttaga gaaaacaaac cgtcgaatca
     5221 cgtttgaata tatcatgttg aatcaagtaa atgatagacc agagcatgcg caacaattag
     5281 cagatctatt aaaagataag aaaaaattag catatgtcaa cttgattcca tataatccag
     5341 tcagtgaaca tgatcaatat tctcgcagtc caaaagctga tgtattgaga ttttatgatg
     5401 tattgaagaa aaacggcgta aactgtgtga tacgtaaaga acatggtaca gatattgatg
     5461 cagcttgcgg acaattgcga agcaagcaaa tgaaaaaaac agttgccaaa taatcgtatc
     5521 ctactcgttt tttcaattac cataaaagga gcagttttct taattaagga actgttcaac
     5581 ttaaataaga gaaaagattc tatagcgaaa gctataaagc tttttttgac aagaaaaacc
     5641 ctcatcaagc aaagaaatgt cctcaatttg atgacagcct gcttgatggg ggttttagca
     5701 attatttaac tgattttctt atatccttgc tggctttctt gtgtagcatg ataagtttct
     5761 acgtcaagaa tggcctgttt aaatttttct cgggtgattt cataaggcac atgtttaata
     5821 tcatttgttg ccatggcttt atctaagatt gcttctaaat cggtcgtgac attgagattc
     5881 atgtcggtta acgatactgg aagttggttc tttttcataa acacatagat tttatcaaac
     5941 aaatcgaact gctgatccat catcaataag gtcagtacac cataactgac agatgctccg
     6001 tgaaggtatc cctccatttt ttctagaaca gtcgtaccgt aatagaatga gtgtgccata
     6061 gcagaattat agttattgtt aactaaaaca gaaaccaatc cggtagtaac aatgatatcc
     6121 gaaacgactt gttcaattgc atatgaggga cgatcgtcgg cactatcttt caatgcttgc
     6181 gtaccataag tcaagagacg atcaatgcac atttttccga tttggattcc taatctatcc
     6241 gtgtagccta gatcatcgcc acgagcagaa aaagtagatt cgacttcttt ggataaagca
     6301 tcgccaatac ctgcccataa gtatttatca ggtgcttcgg caataattgc tgtatcaatg
     6361 aaggtgtgta caggtggttt tgaaggaaag aagagtccgt ccattacgcc ttcttcgtta
     6421 tagatgacac ataccgcagt gacgggcgaa cagttcgaac caatagtggg aaaggtgaag
     6481 actggtttag ctagtttttc accaatgact tttacagtat cgcaagcacg gccaccaccg
     6541 actgcaaaca ggacgtctgc tttttggaca ctttcatgct ggatcaactg ttcaatattt
     6601 ccataagttg aattaccccc gtaccagaga ctggcgacaa cctctatttc ctgtgtcaaa
     6661 gctactttta ttttgttttc tgcctttgaa agtgcagtct tccctccaat cagcactact
     6721 tttgtcccat attctttgac gattccattt gctttttcat acgcatctgt tccaatggta
     6781 taatttggta agaaaacact ttgactcata ttcatttcct tctttcttcg ttgaaacggg
     6841 ttaaaatttt aaagagtgat cgatctgact gcggctgtag atggagtaga ggtgaaccta
     6901 agacaggata agtgatgaat aaggtggcat gaacaccttg aaatcatcaa taagtatcct
     6961 aaaaacgaac aagtacaaaa acattgaaaa cgacaataat gaatttttgt tcctcttagt
     7021 atttctaccg attccctttg cttttttgta attatctaaa aattctaaaa attaagatta
     7081 ttatatgaaa acaggtttta tttgtcaatt cataattggt tttttttaaa gcaaaagata
     7141 atctatatca tgatgaacaa acagagtttt ttcctccaat tgatggcttt cctgatcttt
     7201 cctattttga ataaagtgtt tctgtataat ttttttattt tataagtaag ataaataatg
     7261 aaagaataga gatactgatt ggtagctaaa gatttttgag cgagaacatt tcgttttttc
     7321 aaaaggactg ttagaataag caagaacaag ggggaagacg tatgataatc agtgaatttg
     7381 accgtaataa tccagtattg aaagatcagc tttctgattt actgagactg acttggccgg
     7441 aagaatatgg agacagctcg gcagaagaag tagaagaaat gatgaatcca gaacgaatcg
     7501 cggtagcagc ggtagaccaa gatgagttag taggatttat tggtgcaatc cctcaatacg
     7561 gtatcacagg ttgggaattg catccattag ttgtagaaag ctcccgacga aagaaccaaa
     7621 taggtactcg attagtcaat tacttagaaa aagaagtagc ttccagagga ggaatcacga
     7681 tttatttagg tacggatgat ttagaccatg gaacaacgtt aagtcaaacg gacctgtatg
     7741 agcatacatt tgataaagtg gcttccatcc agaaccttcg tgaacatccg tatgaattct
     7801 atgaaaaatt aggttataaa atcgtaggtg tcttaccaaa tgcaaatggc tgggacaaac
     7861 cggatatttg gatggcaaaa acgattattc ctcgaccaaa ttctcaataa taaaaagagg
     7921 ttgtgacaga agtaatcagc ttcaagaaat aagaaggaat ttacgaaaat tacttcttga
     7981 atttttgtga aattccaact tatttccgaa gaagctactt ttggaacacc gtgtaccaga
     8041 ggttgtgaaa aagtcgctag tttcgagtag taagaaaaat tttgtgaaaa tggcttt
//
LOCUS       DAZULR010000190         5287 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.guided.105, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000190 DAZULR010000000
VERSION     DAZULR010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5287
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.guided.105"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            3..188
                     /locus_tag="ACG8ZV_002967"
     CDS             3..188
                     /locus_tag="ACG8ZV_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFS4998193.1"
                     /translation="MNISVSELARRIGQTPQNFNKKLQRETVTLDELKAIADVLGVKF
                     VQAFILPDGEEIKISNE"
     gene            203..1072
                     /locus_tag="ACG8ZV_002968"
     CDS             203..1072
                     /locus_tag="ACG8ZV_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HFS4998194.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDENRNNLVVPPGAWGDWVNGGGWLVINGCHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGAEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            1053..1787
                     /locus_tag="ACG8ZV_002969"
     CDS             1053..1787
                     /locus_tag="ACG8ZV_002969"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFS4998195.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            1820..2728
                     /locus_tag="ACG8ZV_002970"
     CDS             1820..2728
                     /locus_tag="ACG8ZV_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HFS4998196.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            2725..3267
                     /gene="sat4"
                     /locus_tag="ACG8ZV_002971"
     CDS             2725..3267
                     /gene="sat4"
                     /locus_tag="ACG8ZV_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HFS4998197.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            3360..4154
                     /locus_tag="ACG8ZV_002972"
                     /note="aph(3')-IIIa"
     CDS             3360..4154
                     /locus_tag="ACG8ZV_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HFS4998198.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            4430..4561
                     /locus_tag="ACG8ZV_002973"
                     /pseudo
     CDS             4430..4561
                     /locus_tag="ACG8ZV_002973"
                     /inference="COORDINATES: protein motif:HMM:NF024804.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
     gene            4637..5130
                     /locus_tag="ACG8ZV_002974"
                     /pseudo
     CDS             4637..5130
                     /locus_tag="ACG8ZV_002974"
                     /inference="COORDINATES: protein motif:HMM:NF024676.4"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
BASE COUNT         1821 a          795 c         1186 g         1485 t
ORIGIN      
        1 aaatgaatat aagtgtttcc gaacttgcta gacgtattgg ccagactcca cagaatttca
       61 ataaaaaatt acaacgagaa acagtaacct tggatgagtt gaaggccatt gctgatgtgc
      121 taggtgtcaa gtttgtgcag gcatttattt taccagatgg agaagaaata aaaatatcta
      181 acgaataaag gaggatgttt atatggtagg taatgttatt caaatagtaa cagagaaatt
      241 atcatctttg ccttttatag aaggcatcgt attagggggc tcacgtgcaa gaggcaccca
      301 tacagaaaat tctgatatag atatcggaat ctattacaat tcagactcat ttgacctgac
      361 agcgattaat caaattgcta cagagttgga tgatgagaat agaaacaacc ttgttgtacc
      421 tcccggagcg tggggtgatt gggttaatgg cggtggatgg ttagttataa acgggtgtca
      481 tgttgacttg atattacgtg atataaaacg ggtggaacaa ataatcaaag atacggagca
      541 aggaattgtt actgccaatt atcagaccgg gcatccccat ggttatataa gtgctatgta
      601 tcgtggagaa ttagcgatta gtaaaatact atatgctaag aacgaaagct tatgcgaatt
      661 aaaaaagcag gcagaaattt accctactgc tctaaagaaa agcttgatga acttttttat
      721 atttgaagct gaattctctt taatgtttgt aaaagcaaat gcgggggcag aggataaata
      781 ttatattgca ggccatgttt ttcgtattat ttcatgctta aatcaagtac tatttgcatg
      841 taataatgct tattgcatta acgaaaagaa agctataaaa ctgcttgaaa cttttgaata
      901 taaacctgaa aaatatgccg aaagagttaa tcatattttt gaagtactcg gtctttctct
      961 ttttgaatgc tacgacatga ccgagaaact ttataaagaa gtgaatgaaa ttgtatcgga
     1021 gataaataac tttttaaacg aggagagttc agatgaaaga aaacaaatat gatgataata
     1081 tattttttca aaaatacagt caaatgagtc gctcgcagaa aggactggct ggtgcgggag
     1141 aatgggagac tttgaaaaag atgctacctg attttaaggg taagcgtgtg cttgatttag
     1201 gatgcggcta tggatggcac tgtatatatg cgatggaaaa cggtgcttcc tctgtagtag
     1261 gtgttgatat ttctcataaa atgctcgaag tagcaaaagg aaaaacccat tttccacaga
     1321 ttgaatatga atgctgtgcc atagaagatg tggatttccc agaggagagc tttgatgtaa
     1381 tactaagttc gcttgcgttt cattatgtag cagactatga gaatttaata aaaaagatat
     1441 ataggatgct gaaggctggt ggcaatttag tttttacagt tgaacatcct gtttttactg
     1501 ctcatggaac acaagactgg tattataacg aaaaaggaga aatactgcat ttcccggtgg
     1561 acaattatta ttatgagggc aaacggacag ctatgttttt ggaagaaaag gttacaaaat
     1621 atcatagaac actgaccaca tatctaaata cactgctttc aaatagtttt ataataaatc
     1681 agattgtgga gccacagccg ccagagaaca tgatggatat tccggggatg gcggatgaaa
     1741 tgcgacgccc aatgatgctg attgtatcgg caaaaaagaa gatgtaataa tatagaaaaa
     1801 ataaacgagg agtatgtaaa tgagatcaga aaaagaaatg atggatttag tactttcttt
     1861 agcagaacag gatgaacgta ttcgaattgt gacccttgag gggtcacgcg caaatattaa
     1921 tatacctaaa gatgaatttc aggattatga tattacatat tttgtaagtg atatagaacc
     1981 gtttatatct aatgatgact ggcttaatca atttgggaat ataataatga tgcaaaagcc
     2041 ggaggatatg gaattattcc cacctgaaga aaagggattt tcctatctta tgctatttga
     2101 tgattacaat aaaattgatc ttaccttatt gcccttggaa gagttagata attacctaaa
     2161 gggcgataaa ttaataaagg ttctaattga taaagattgt agaattaaaa gggacatagt
     2221 tccgactgat atagattatc atgtaagaaa gccaagcgca agggagtatg atgattgctg
     2281 caatgaattt tggaatgtaa caccttatgt tattaaagga ttgtgccgta aggaaatttt
     2341 atttgctatt gatcatttta atcagattgt tcgccatgag ctgctgagaa tgatatcatg
     2401 gaaggtcggc atcgaaacag gctttaaatt aagtgtaggc aagaactata agtttattga
     2461 aaggtatata tccgaggatt tgtgggagaa acttttgtcc acctaccgga tggattccta
     2521 tgaaaacata tgggaagcat tatttctatg ccatcaattg ttcagggcgg tatccggtga
     2581 ggtggcggaa aggcttcatt atgcctatcc ggagtatgat aggaatataa caaaatatac
     2641 cagggacatg tataaaaaat acactggtaa aaccggctgc ctggatagca catatgccgc
     2701 tgatatagaa gagaggcggg aacagtgatt acagaaatga aagcagggca cctgaaagat
     2761 atcgataaac ccagcgaacc atttgaggtg ataggtaaga ttataccgag gtatgaaaac
     2821 gagaattgga cctttacaga attactctat gaagcgccat atttaaaaag ctaccaagac
     2881 gaagaggatg aagaggatga ggaggcagat tgccttgaat atattgacaa tactgataag
     2941 ataatatatc tttactacca agacgataaa tgcgtcggaa aagttaaact gcgaaaaaat
     3001 tggaaccggt acgcttatat agaagatatc gccgtatgta aggatttcag ggggcaaggc
     3061 ataggcagcg cgcttatcaa tatatctata gaatgggcaa agcataaaaa cttgcatgga
     3121 ctaatgcttg aaacccagga caataacctt atagcttgta aattctatca taattgtggt
     3181 ttcaaaatcg gctccgtcga tactatgtta tacgccaact ttgaaaacaa ctttgaaaaa
     3241 gctgttttct ggtatttaag gttttagaat gcaaggaaca gtgaattgga gttcgtcttg
     3301 ttataattag cttcttgggg tatctttaaa tactgtagaa aagaggaagg aaataataaa
     3361 tggctaaaat gagaatatca ccggaattga aaaaactgat cgaaaaatac cgctgcgtaa
     3421 aagatacgga aggaatgtct cctgctaagg tatataagct ggtgggagaa aatgaaaacc
     3481 tatatttaaa aatgacggac agccggtata aagggaccac ctatgatgtg gaacgggaaa
     3541 aggacatgat gctatggctg gaaggaaagc tgcctgttcc aaaggtcctg cactttgaac
     3601 ggcatgatgg ctggagcaat ctgctcatga gtgaggccga tggcgtcctt tgctcggaag
     3661 agtatgaaga tgaacaaagc cctgaaaaga ttatcgagct gtatgcggag tgcatcaggc
     3721 tctttcactc catcgacata tcggattgtc cctatacgaa tagcttagac agccgcttag
     3781 ccgaattgga ttacttactg aataacgatc tggccgatgt ggattgcgaa aactgggaag
     3841 aagacactcc atttaaagat ccgcgcgagc tgtatgattt tttaaagacg gaaaagcccg
     3901 aagaggaact tgtcttttcc cacggcgacc tgggagacag caacatcttt gtgaaagatg
     3961 gcaaagtaag tggctttatt gatcttggga gaagcggcag ggcggacaag tggtatgaca
     4021 ttgccttctg cgtccggtcg atcagggagg atatcgggga agaacagtat gtcgagctat
     4081 tttttgactt actggggatc aagcctgatt gggagaaaat aaaatattat attttactgg
     4141 atgaattgtt ttagtaccta gatttagatg tctaaaaagc tttaactaca agctttttag
     4201 acatctaatc ttttctgaag tacatccgca actgtccata ctctgatgtt ttatatcttt
     4261 tctaaaagtt cgctagatag agttctatat tagagatgta aagagttttg gtgaagaggt
     4321 ttgtgagtat ggcttttata accagggtgc aatgagaagc actaacagca gctagcttaa
     4381 gaacgcatag gatatacttt ttatggaagt cacagaggag gaataaaatt tgaacaggat
     4441 taacagagta acctctattc ttattcagct gcaatcaaaa aaaataattc ctgccaaaga
     4501 aattgcacag cgatttaata taagcttaag gacagtttac agagatatcc ggacacttga
     4561 agaagccgga ataccaattg gatctgaggc cggaaaagga tattttcttg tagagggctt
     4621 cctacttccg ccggtaatgt ttacagcggc ggaagtgggt gcattgatta cagcagggaa
     4681 atttttaaat tgccatggag atgaatcatt tataaaggat tttgattcag ctatgtataa
     4741 aatcaaatct attttgaagc atggtgaaaa aaactatgca caggagttgg agaacagtat
     4801 taacgtgtac agcacatctg gacagaaaaa tacattggcg gataacgtta ttgcagcaat
     4861 tcagactgca atctgcaata aaagggtaat atcaattcaa tatcctgcat caggagggca
     4921 agaaccggaa agcagaatga tagagcctat atcactgggg ttttatgaac agaactggta
     4981 cttaatcggt tttgcaggct aagaaatgaa tataggaatt ttcgtgtgga tcggattaaa
     5041 agcatttgca tagaagaaga gctctgtcaa agccatgatg gctctttgga acaaatatta
     5101 aaacaaatgc tttcatataa aaaactatat gccctacaat gccgttgtaa aaattgggga
     5161 aaagggatat attgatttta tatctttctc aaaataaata taaaagccct ttaaagaggg
     5221 cttttatata ttaatcacaa atcacttatc acaaatcaca agtgattaat cacaaatcac
     5281 ttgtgat
//
LOCUS       DAZULR010000191         4802 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.guided.113, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000191 DAZULR010000000
VERSION     DAZULR010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4802
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.guided.113"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            92..787
                     /gene="vanR-A"
                     /locus_tag="ACG8ZV_002975"
     CDS             92..787
                     /gene="vanR-A"
                     /locus_tag="ACG8ZV_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-A"
                     /protein_id="HFS4998199.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            765..1919
                     /locus_tag="ACG8ZV_002976"
     CDS             765..1919
                     /locus_tag="ACG8ZV_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-A"
                     /protein_id="HFS4998200.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            2134..3102
                     /locus_tag="ACG8ZV_002977"
     CDS             2134..3102
                     /locus_tag="ACG8ZV_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HFS4998201.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            3095..4126
                     /gene="vanA"
                     /locus_tag="ACG8ZV_002978"
     CDS             3095..4126
                     /gene="vanA"
                     /locus_tag="ACG8ZV_002978"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HFS4998202.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            4132..4740
                     /locus_tag="ACG8ZV_002979"
     CDS             4132..4740
                     /locus_tag="ACG8ZV_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HFS4998203.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT         1482 a          921 c         1119 g         1280 t
ORIGIN      
        1 catggccttt tatcttttac acaattatat ggactttatc ctataatctg ataaattatt
       61 aagggcaaac ttatgtgaaa gggtgataac tatgagcgat aaaatactta ttgtggatga
      121 tgaacatgaa attgccgatt tggttgaatt atacttaaaa aacgagaatt atacggtttt
      181 caaatactat accgccaaag aagcattgga atgtatagac aagtctgaga ttgaccttgc
      241 catattggac atcatgcttc ccggcacaag cggccttact atctgtcaaa aaataaggga
      301 caagcacacc tatccgatta tcatgctgac cgggaaagat acagaggtag ataaaattac
      361 agggttaaca atcggcgcgg atgattatat aacgaagccc tttcgcccac tggagttaat
      421 tgctcgggta aaggcccagt tgcgccgata caaaaaattc agtggagtaa aggagcagaa
      481 cgaaaatgtt atcgtccact ccggccttgt cattaatgtt aacacccatg agtgttatct
      541 gaacgagaag cagttatccc ttactcccac cgagttttca atactgcgaa tcctctgtga
      601 aaacaagggg aatgtggtta gctccgagct gctatttcat gagatatggg gcgacgaata
      661 tttcagcaag agcaacaaca ccatcaccgt gcatatccgg catttgcgcg aaaaaatgaa
      721 cgacaccatt gataatccga aatatataaa aacggtatgg ggggttggtt ataaaattga
      781 aaaataaaaa aaacgactat tccaaactag aacgaaaact ttacatgtat atcgttgcaa
      841 ttgttgtggt agcaattgta ttcgtgttgt atattcgttc aatgatccga gggaaacttg
      901 gggattggat cttaagtatt ttggaaaaca aatatgactt aaatcacctg gacgcgatga
      961 aattatatca atattccata cggaacaata tagatatctt tatttatgtg gcgattgtca
     1021 ttagtattct tattctatgt cgcgtcatgc tttcaaaatt cgcaaaatac tttgacgaga
     1081 taaataccgg cattgatgta cttattcaga acgaagataa acaaattgag ctttctgcgg
     1141 aaatggatgt tatggaacaa aagctcaaca cattaaaacg gactctggaa aagcgagagc
     1201 aggatgcaaa gctggccgaa caaagaaaaa atgacgttgt tatgtacttg gcgcacgata
     1261 ttaaaacgcc ccttacatcc attatcggtt atttgagcct gcttgacgag gctccagaca
     1321 tgccggtaga tcaaaaggca aagtatgtgc atatcacgtt ggacaaagcg tatcgactcg
     1381 aacagctaat cgacgagttt tttgagatta cacggtataa cctacaaacg ataacgctaa
     1441 caaaaacgca catagaccta tactatatgc tggtgcagat gaccgatgaa ttttatcctc
     1501 agctttccgc acatggaaaa caggcggtta ttcacgcccc cgaggatctg accgtgtccg
     1561 gcgaccctga taaactcgcg agagtcttta acaacatttt gaaaaacgcc gctgcataca
     1621 gtgaggataa cagcatcatt gacattaccg cgggcctctc cggggatgtg gtgtcaatcg
     1681 aattcaagaa cactggaagc atcccaaaag ataagctagc tgccatattt gaaaagttct
     1741 ataggctgga caatgctcgt tcttccgata cgggtggcgc gggacttgga ttggcgattg
     1801 caaaagaaat tattgttcag catggagggc agatttacgc ggaaagcaat gataactata
     1861 cgacgtttag ggtagagctt ccagcgatgc cagacttggt tgataaaagg aggtcctaag
     1921 agatgtatat aattttttag gaaaatctca aggttatctt tactttttct taggaaatta
     1981 acaatttaat attaagaaac ggctcgttct tacacggtag acttaatacc gtaagaacga
     2041 gccgttttcg ttcttcagag aaagatttga caagattacc attggcatcc ccgttttatt
     2101 tggtgccttt cacagaaagg gttggtctta attatgaata acatcggcat tactgtttat
     2161 ggatgtgagc aggatgaggc agatgcattc catgctcttt cgcctcgctt tggcgttatg
     2221 gcaacgataa ttaacgccaa cgtgtcggaa tccaacgcca aatccgcgcc tttcaatcaa
     2281 tgtatcagtg tgggacataa atcagagatt tccgcctcta ttcttcttgc gctgaagaga
     2341 gccggtgtga aatatatttc tacccgaagc atcggctgca atcatataga tacaactgct
     2401 gctaagagaa tgggcatcac tgtcgacaat gtggcgtact cgccggatag cgttgccgat
     2461 tatactatga tgctaattct tatggcagta cgcaacgtaa aatcgattgt gcgctctgtg
     2521 gaaaaacatg atttcaggtt ggacagcgac cgtggcaagg tactcagcga catgacagtt
     2581 ggtgtggtgg gaacgggcca gataggcaaa gcggttattg agcggctgcg aggatttgga
     2641 tgtaaagtgt tggcttatag tcgcagccga agtatagagg taaactatgt accgtttgat
     2701 gagttgctgc aaaatagcga tatcgttacg cttcatgtgc cgctcaatac ggatacgcac
     2761 tatattatca gccacgaaca aatacagaga atgaagcaag gagcatttct tatcaatact
     2821 gggcgcggtc cacttgtaga tacctatgag ttggttaaag cattagaaaa cgggaaactg
     2881 ggcggtgccg cattggatgt attggaagga gaggaagagt ttttctactc tgattgcacc
     2941 caaaaaccaa ttgataatca atttttactt aaacttcaaa gaatgcctaa cgtgataatc
     3001 acaccgcata cggcctatta taccgagcaa gcgttgcgtg ataccgttga aaaaaccatt
     3061 aaaaactgtt tggattttga aaggagacag gagcatgaat agaataaaag ttgcaatact
     3121 gtttgggggt tgctcagagg agcatgacgt atcggtaaaa tctgcaatag agatagccgc
     3181 taacattaat aaagaaaaat acgagccgtt atacattgga attacgaaat ctggtgtatg
     3241 gaaaatgtgc gaaaaacctt gcgcggaatg ggaaaacgac aattgctatt cagctgtact
     3301 ctcgccggat aaaaaaatgc acggattact tgttaaaaag aaccatgaat atgaaatcaa
     3361 ccatgttgat gtagcatttt cagctttgca tggcaagtca ggtgaagatg gatccataca
     3421 aggtctgttt gaattgtccg gtatcccttt tgtaggctgc gatattcaaa gctcagcaat
     3481 ttgtatggac aaatcgttga catacatcgt tgcgaaaaat gctgggatag ctactcccgc
     3541 cttttgggtt attaataaag atgataggcc ggtggcagct acgtttacct atcctgtttt
     3601 tgttaagccg gcgcgttcag gctcatcctt cggtgtgaaa aaagtcaata gcgcggacga
     3661 attggactac gcaattgaat cggcaagaca atatgacagc aaaatcttaa ttgagcaggc
     3721 tgtttcgggc tgtgaggtcg gttgtgcggt attgggaaac agtgccgcgt tagttgttgg
     3781 cgaggtggac caaatcaggc tgcagtacgg aatctttcgt attcatcagg aagtcgagcc
     3841 ggaaaaaggc tctgaaaacg cagttataac cgttcccgca gacctttcag cagaggagcg
     3901 aggacggata caggaaacgg caaaaaaaat atataaagcg ctcggctgta gaggtctagc
     3961 ccgtgtggat atgtttttac aagataacgg ccgcattgta ctgaacgaag tcaatactct
     4021 gcccggtttc acgtcataca gtcgttatcc ccgtatgatg gccgctgcag gtattgcact
     4081 tcccgaactg attgaccgct tgatcgtatt agcgttaaag gggtgataag catggaaata
     4141 ggatttactt ttttagatga aatagtacac ggtgttcgtt gggacgctaa atatgccact
     4201 tgggataatt tcaccggaaa accggttgac ggttatgaag taaatcgcat tgtagggaca
     4261 tacgagttgg ctgaatcgct tttgaaggca aaagaactgg ctgctaccca agggtacgga
     4321 ttgcttctat gggacggtta ccgtcctaag cgtgctgtaa actgttttat gcaatgggct
     4381 gcacagccgg aaaataacct gacaaaggaa agttattatc ccaatattga ccgaactgag
     4441 atgatttcaa aaggatacgt ggcttcaaaa tcaagccata gccgcggcag tgccattgat
     4501 cttacgcttt atcgattaga cacgggtgag cttgtaccaa tggggagccg atttgatttt
     4561 atggatgaac gctctcatca tgcggcaaat ggaatatcat gcaatgaagc gcaaaatcgc
     4621 agacgtttgc gctccatcat ggaaaacagt gggtttgaag catatagcct cgaatggtgg
     4681 cactatgtat taagagacga accatacccc aatagctatt ttgatttccc cgttaaataa
     4741 acttttaacc gttgcacgga caaacggttc tgttgcaaag ttttaaataa agaataaaat
     4801 cc
//
LOCUS       DAZULR010000192         2771 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.guided.131, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000192 DAZULR010000000
VERSION     DAZULR010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2771
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.guided.131"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            110..193
                     /locus_tag="ACG8ZV_002980"
     CDS             110..193
                     /locus_tag="ACG8ZV_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031556 - transcriptional attenuation by
                     ribosome [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HFS4998204.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            318..1055
                     /gene="erm(B)"
                     /locus_tag="ACG8ZV_002981"
     CDS             318..1055
                     /gene="erm(B)"
                     /locus_tag="ACG8ZV_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HFS4998205.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(1318..2181)
                     /locus_tag="ACG8ZV_002982"
     CDS             complement(1318..2181)
                     /locus_tag="ACG8ZV_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HFS4998206.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAL
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTP
                     PIPKTPKLPGI"
     gene            complement(2183..2455)
                     /locus_tag="ACG8ZV_002983"
     CDS             complement(2183..2455)
                     /locus_tag="ACG8ZV_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HFS4998207.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
     gene            complement(2472..2681)
                     /locus_tag="ACG8ZV_002984"
     CDS             complement(2472..2681)
                     /locus_tag="ACG8ZV_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HFS4998208.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
BASE COUNT          851 a          487 c          443 g          990 t
ORIGIN      
        1 ttatttgata gtagatttaa aactttgcaa cagaaccaaa attttgtata ataggaattg
       61 aagttaaatt agatgctaaa aatttgtaat taagaaggag ggattcgtca tgttggtatt
      121 ccaaatgcgt aatgtagata aaacatctac cgttttgaaa cagactaaaa acagtgatta
      181 cgcagataaa taaatacgtt agattaattc ctaccagtga ctaatcttat gactttttaa
      241 acagataact aaaattacaa acaaatcgtt taacttctgt atttatttat agatgtaatc
      301 acttcaggag tgattacatg aacaaaaata taaaatattc tcaaaacttt ttaacgagtg
      361 aaaaagtact caaccaaata ataaaacaat tgaatttaaa agaaaccgat accgtttacg
      421 aaattggaac aggtaaaggg catttaacga cgaaactggc taaaataagt aaacaggtaa
      481 cgtctattga attagacagt catctattca acttatcgtc agaaaaatta aaactgaaca
      541 ctcgtgtcac tttaattcac caagatattc tacagtttca attccctaac aaacagaggt
      601 ataaaattgt tgggaatatt ccttaccatt taagcacaca aattattaaa aaagtggttt
      661 ttgaaagcca tgcgtctgac atctatctga ttgttgaaga aggattctac aagcgtacct
      721 tggatattca ccgaacacta gggttgctct tgcacactca agtctcgatt cagcaattgc
      781 ttaagctgcc agcggaatgc tttcatccta aaccaaaagt aaacagtgtc ttaataaaac
      841 ttacccgcca taccacagat gttccagata aatattggaa gctatatacg tactttgttt
      901 caaaatgggt caatcgagaa tatcgtcaac tgtttactaa aaatcagttt catcaagcaa
      961 tgaaacacgc caaagtaaac aatttaagta ccgttactta tgagcaagta ttgtctattt
     1021 ttaatagtta tctattattt aacgggagga aataattcta tgagtcgctt ttgtaaattt
     1081 ggaaagttac acgttactaa agggaatgta gataaattat taggtatagg gcacctctaa
     1141 taactaccaa ttaattcacc tcaaaatgaa attagaaaaa aacagcgaaa tttttaaatc
     1201 tatttcttat cgatacaaat tcctcgtagg cgctcgggac cccaacatga ggaaatgttt
     1261 ttataaaaaa agagtagtta ccgttttttg gtaactactc ttttcctttt ttaaggttta
     1321 aatacctgga agtttaggtg ttttgggtat tggtggtgta ggtagctgca agctttccat
     1381 tttttgttga attgctttaa attcaggggt ttcttggtgt tgattttgaa ccattttttg
     1441 ctctattctc tccaaagtcg gttgaatttc tttccctgat actttacgat ttaattctct
     1501 ttctaaggtc tctttcggac taatggaagg cgtttctaag cttgaataga gtttcactcc
     1561 ttctctattg taaagcctta tatcgctaaa taagcccgtt ttatgaaggg tttctaaatt
     1621 ggtcggtaag tttttgacaa caatatcatg cgcttgtttt ggtgttgccc tagctgtcat
     1681 tggatcatct gcatacatgg tttcatatcg ttcaatcgtt cctaagtatg attcaatttt
     1741 cggtactgcc atgacgtata tttttgtttc ataaccttta gattgaagca ttgtggctgt
     1801 ttgaatggga acgtctgttg ttcgtcctgt tccttcaatc actaaattat agccttgatc
     1861 gcttaaacgg ctaataagtg cttctgtcat gcgattcgaa taaggggtaa cgtgttttac
     1921 tacgtctttt tcatagagtt tcactaattc gtcaaaattt gggtgctgtt gtttaaaggt
     1981 atcattatca atgacaataa cattcccttg tgtttcttca aaaattgctg atcgcaaact
     2041 ggttttccct gaccctggtt gcccaccaag taaaaaagcg gttggcgatt caaccgctag
     2101 tctattttta gttagtcgtt caacattctt ttctaaacga tcttcaaatt gcttttcggt
     2161 gaagtcagta atattcgcca tgttaagcca ctttctcttt attcaaaatt tgttttgaat
     2221 attgattcat tgaccgccaa tactcatgaa tagcttgtaa ttcttcaaat ggttgttgaa
     2281 ataaatcaac ttcttgtgcc acttctaatt gatttaaaag attcacttct agtaaacgag
     2341 tatttttagt atctagttca tgattcaaaa cataatttaa tacccgatta taaacacttg
     2401 ccgataactc attaatgatt tcaatttcaa atgttttttc atacgtaact gccatttcat
     2461 tttcactcct tttaaagttt gtcaggtaaa tatttccgta tatattcttc taaggcttga
     2521 tccataactt cttttacgtt tccgccattc tttgctgttt cgatttttat gatatggtgc
     2581 aagtcggcac gaacacgaac cgtcttatcc cccattatat ctttttttgc gctgattggc
     2641 gtatcatttc gttttgcttt ctgtgcgcct aaatttccca cgatcgctca cttctttcta
     2701 tttcttctta ctatttattt tatcatcacc tatcacaaat cacaagtgat ttgtgattaa
     2761 tcacttgtga t
//
LOCUS       DAZULR010000193         2308 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.guided.139, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000193 DAZULR010000000
VERSION     DAZULR010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2308
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.guided.139"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            46..438
                     /locus_tag="ACG8ZV_002985"
     CDS             46..438
                     /locus_tag="ACG8ZV_002985"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFS4998209.1"
                     /translation="MKLLFIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDEIVYVYDYEKGDK"
     gene            439..1878
                     /locus_tag="ACG8ZV_002986"
     CDS             439..1878
                     /locus_tag="ACG8ZV_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase
                     APH(2'')-Ia"
                     /protein_id="HFS4998210.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYDGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPI
                     ETIVYGIKNIKQEFIENGRKEIYKRTYKD"
     gene            complement(2008..>2308)
                     /locus_tag="ACG8ZV_002987"
     CDS             complement(2008..>2308)
                     /locus_tag="ACG8ZV_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015077585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFS4998211.1"
                     /translation="LFDSRFKTLQQNQPKYSKACASLDDGFEDAFQYTVQGNSHNRLK
                     STNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
BASE COUNT          918 a          207 c          394 g          789 t
ORIGIN      
        1 acactaaaat agattttttg gaaaactttg caacagaacc tcctattgaa actattgttt
       61 attgatgata atatggtttt tgatattgat aatttaaaag gatttcttaa tgataccagt
      121 tcatttgggt ttatagctaa agaaaataat aaaattatag gatttgcata ttgctataca
      181 cttttaagac ctgatggaaa aacaatgttt tatttacact caataggaat gttacctaac
      241 tatcaagaca aaggttatgg ttcaaaatta ttatctttta ttaaggaata ttctaaagag
      301 attggttgtt ctgaaatgtt tttaataact gataaaggta atcctagagc ttgccatgta
      361 tatgaaaaat taggtggtaa aaatgattat aaagatgaaa tagtatatgt atatgattat
      421 gaaaaaggtg ataaataaat gaatatagtt gaaaatgaaa tatgtataag aactttaata
      481 gatgatgatt ttcctttgat gttaaaatgg ttaactgatg aaagagtatt agaattttat
      541 gatggtagag ataaaaaata tacattagaa tcattaaaaa aacattatac agagccttgg
      601 gaagatgaag tttttagagt aattattgaa tataacaatg ttcctattgg atatggacaa
      661 atatataaaa tgtatgatga gttatatact gattatcatt atccaaaaac tgatgagata
      721 gtctatggta tggatcaatt tataggagag ccaaattatt ggagtaaagg aattggtaca
      781 agatatatta aattgatttt tgaatttttg aaaaaagaaa gaaatgctaa tgcagttatt
      841 ttagaccctc ataaaaataa tccaagagca ataagggcat accaaaaatc tggttttaga
      901 attattgaag atttgccaga acatgaatta cacgagggca aaaaagaaga ttgttattta
      961 atggaatata gatatgatga taatgccaca aatgttaagg caatgaaata tttaattgag
     1021 cattactttg ataatttcaa agtagatagt attgaaataa tcggtagtgg ttatgatagt
     1081 gtggcatatt tagttaataa tgaatacatt tttaaaacaa aatttagtac taataagaaa
     1141 aaaggttatg caaaagaaaa agcaatatat aattttttaa atacaaattt agaaactaat
     1201 gtaaaaattc ctaatattga atattcgtat attagtgatg aattatctat actaggttat
     1261 aaagaaatta aaggaacttt tttaacacca gaaatttatt ctactatgtc agaagaagaa
     1321 caaaatttgt taaaacgaga tattgccagt tttttaagac aaatgcacgg tttagattat
     1381 acagatatta gtgaatgtac tattgataat aaacaaaatg tattagaaga gtatatattg
     1441 ttgcgtgaaa ctatttataa tgatttaact gatatagaaa aagattatat agaaagtttt
     1501 atggaaagac taaatgcaac aacagttttt gagggtaaaa agtgtttatg ccataatgat
     1561 tttagttgta atcatctatt gttagatggc aataatagat taactggaat aattgatttt
     1621 ggagattctg gaattataga tgaatattgt gattttatat acttacttga agatagtgaa
     1681 gaagaaatag gaacaaattt tggagaagat atattaagaa tgtatggaaa tatagatatt
     1741 gagaaagcaa aagaatatca agatatagtt gaagaatatt atcctattga aactattgtt
     1801 tatggaatta aaaatattaa acaggaattt atcgaaaatg gtagaaaaga aatttataaa
     1861 aggacttata aagattgatt atataatata tgaaaagcta ttataaaaga cattagtatt
     1921 aaatagttta aaaaaatgaa aaataataaa ggaagtgagt caagtccaga ctcctgtgta
     1981 aaatgctata caatgttttt accatttcta cttatcaaaa ttgatgtatt ttcttgaaga
     2041 ataaatccat tcatcatgta ggtccataag aacggctcca attaagcgat tggctgatgt
     2101 ttgattgggg aagatgcgaa taatcttttc tcttctgcgt acttcttgat tcagtcgttc
     2161 aattagattg gtactcttta gtcgattgtg ggaatttcct tgtacggtat attgaaaggc
     2221 gtcttcgaat ccatcatcca atgatgcgca agcttttgaa tattttggtt ggttctgttg
     2281 caaagtttta aatctactat caaataag
//
LOCUS       DAZULR010000194         1313 bp    DNA     linear   BCT 26-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE5143
            SAMEA115707522-rid22580393.guided.153, whole genome shotgun
            sequence.
ACCESSION   DAZULR010000194 DAZULR010000000
VERSION     DAZULR010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115707522
            Sequence Read Archive: ERR13197251
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 04-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002288055.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002288055.1
            Genome Coverage       :: 186x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 11:03:56
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,990
            CDSs (total)                      :: 2,927
            Genes (coding)                    :: 2,836
            CDSs (with protein)               :: 2,836
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            CDSs (without protein)            :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 39 of 91
            Pseudo Genes (incomplete)         :: 47 of 91
            Pseudo Genes (internal stop)      :: 26 of 91
            Pseudo Genes (multiple problems)  :: 18 of 91
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1313
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115707522-rid22580393.guided.153"
                     /isolate="VRE5143"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            112..461
                     /locus_tag="ACG8ZV_002988"
                     /pseudo
     CDS             112..461
                     /locus_tag="ACG8ZV_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741963.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(733..1023)
                     /locus_tag="ACG8ZV_002989"
     CDS             complement(733..1023)
                     /locus_tag="ACG8ZV_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFS4998212.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1231..>1313)
                     /locus_tag="ACG8ZV_002990"
     CDS             complement(1231..>1313)
                     /locus_tag="ACG8ZV_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFS4998213.1"
                     /translation="KLEKAKDEVEDTADKSQQIVEEHLRK"
BASE COUNT          395 a          257 c          188 g          473 t
ORIGIN      
        1 ttctattatg tttgttcatt tttatactcc ttcttatatt tcctaataga gtataacata
       61 gctttaagca ttacttaaag ataacttaaa agttatcttt taaatactta attgttaaat
      121 accttatttg atgcaaaaga aatctacgat agtcaacaaa aaaattttca ttatatccag
      181 aaaaattttt cttagttaag gacctatgga ttgcagtaat gcagaattcg tcgaataaac
      241 tgccaaagac atacaatcat attgctttta aaattgacga acaagatata gattcgtttg
      301 tctcaaaaat ccaaatgtta ggtttaactg tcgaaccagg acgttctcgt gtgaaaggcg
      361 aggcttcttc aatttacttt tacgactatg ataatcacct cttcgagtta cataccggta
      421 ctctccagga acgtttaaaa tcctacaatt ccactacctg agactagtaa tgactagtct
      481 ctttttatgg cctctgatcc ccccattgag cgaatactaa tagggcttcg aattgatctg
      541 ttcaatcttt aagcaatatc cctcaaatga gtttggaaag tttagtgatt catcacaaat
      601 acttaaatac atgtagttat atatagattg aggttcttgt gagcgtatgc tcgtgtgggt
      661 tcaaatccca tcgtctgcat ccatctttcc aaaacaagcg gctaggacat ttttgtctca
      721 gccgcttgtt ttctagttta ttctttcatc ttgtcggacc ttttttcttg ggtatagact
      781 tttctcatat tctaccacaa ttttgggttt ccctaacaca tgataggatc tcacaacaaa
      841 ttgctttcta ttattataat aacctgtaac gactaacttc atcccttcgt ctacttcagc
      901 taggaagttc aaactatggg aagcaatcaa acaattgacc ccatttaaac tgaaacggat
      961 caacggtctg gcactaactt gcaaagtacg gatcttatct actgttccat attttttctc
     1021 cataaccttc acctcaatac cattatacga acatacattc cctttgtaaa gaagaaactc
     1081 tgttttatct ttttgacttt ttgtctatta cctttcttaa aatcatattg gcacttcctg
     1141 cgaagatgaa ggacatgtac taaaaaaaag aggcagcagt atagattact gttgcttctt
     1201 tactaattta ggtttacttg ttaagaaaga ttatttacgc aaatgttctt caacaatttg
     1261 ctgagattta tcagctgtat cttccacttc atcttttgct ttttctaact ttt
//
